-- dump date 20140619_154558 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001281281.1 148659758 5211618 1..1524 1 NC_009525.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1524 dnaA 5211618 dnaA Mycobacterium tuberculosis H37Ra chromosomal replication initiation protein YP_001281281.1 1 D 419947 CDS YP_001281282.1 148659759 5212894 2052..3260 1 NC_009525.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3260 dnaN 5212894 dnaN Mycobacterium tuberculosis H37Ra DNA polymerase III subunit beta YP_001281282.1 2052 D 419947 CDS YP_001281283.1 148659760 5213978 3280..4437 1 NC_009525.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4437 recF 5213978 recF Mycobacterium tuberculosis H37Ra recombination protein F YP_001281283.1 3280 D 419947 CDS YP_001281284.1 148659761 5212895 4434..4997 1 NC_009525.1 hypothetical protein 4997 5212895 MRA_0004 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281284.1 4434 D 419947 CDS YP_001281285.1 148659762 5212896 5123..7267 1 NC_009525.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 7267 gyrB 5212896 gyrB Mycobacterium tuberculosis H37Ra DNA gyrase subunit B YP_001281285.1 5123 D 419947 CDS YP_001281286.1 148659763 5212897 7302..9818 1 NC_009525.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 9818 gyrA 5212897 gyrA Mycobacterium tuberculosis H37Ra DNA gyrase subunit A YP_001281286.1 7302 D 419947 CDS YP_001281287.1 148659764 5212898 9914..10828 1 NC_009525.1 hypothetical protein 10828 5212898 MRA_0007 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281287.1 9914 D 419947 CDS YP_001281288.1 148659765 5214732 complement(11874..12311) 1 NC_009525.1 hypothetical protein 12311 5214732 MRA_0008 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281288.1 11874 R 419947 CDS YP_001281289.1 148659766 5214733 12468..13016 1 NC_009525.1 iron-regulated peptidyl-prolyl cis-trans isomerase A 13016 ppiA 5214733 ppiA Mycobacterium tuberculosis H37Ra iron-regulated peptidyl-prolyl cis-trans isomerase A YP_001281289.1 12468 D 419947 CDS YP_001281290.1 148659767 5214734 complement(13133..13558) 1 NC_009525.1 hypothetical protein 13558 5214734 MRA_0010 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281290.1 13133 R 419947 CDS YP_001281291.1 148659768 5214735 complement(13665..14549) 1 NC_009525.1 IS6110 transposase 14549 5214735 MRA_0011 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001281291.1 13665 R 419947 CDS YP_001281292.1 148659769 5214736 complement(14600..14926) 1 NC_009525.1 IS6110 hypothetical protein 14926 5214736 MRA_0012 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001281292.1 14600 R 419947 CDS YP_001281293.1 148659770 5212131 complement(15072..15353) 1 NC_009525.1 integral membrane protein involved in inhibition of the Z-ring formation; septation inhibitor protein 15353 5212131 MRA_0013 Mycobacterium tuberculosis H37Ra septation inhibitor protein YP_001281293.1 15072 R 419947 CDS YP_001281294.1 148659771 5212132 15447..16235 1 NC_009525.1 hypothetical protein 16235 5212132 MRA_0014 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281294.1 15447 D 419947 CDS YP_001281295.1 148659772 5212133 16272..16970 1 NC_009525.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 16970 trpG 5212133 trpG Mycobacterium tuberculosis H37Ra para-aminobenzoate synthase component II YP_001281295.1 16272 D 419947 CDS YP_001281296.1 148659773 5212134 complement(16948..18828) 1 NC_009525.1 serine/threonine protein kinase 18828 pknB 5212134 pknB Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001281296.1 16948 R 419947 CDS YP_001281297.1 148659774 5212135 complement(18825..20120) 1 NC_009525.1 serine/threonine protein kinase 20120 pknA 5212135 pknA Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001281297.1 18825 R 419947 CDS YP_001281298.1 148659775 5212136 complement(20117..21592) 1 NC_009525.1 penicillin-binding protein PbpA 21592 pbpA 5212136 pbpA Mycobacterium tuberculosis H37Ra penicillin-binding protein PbpA YP_001281298.1 20117 R 419947 CDS YP_001281299.1 148659776 5212137 complement(21589..22998) 1 NC_009525.1 cell division protein FtsA 22998 rodA 5212137 rodA Mycobacterium tuberculosis H37Ra cell division protein FtsA YP_001281299.1 21589 R 419947 CDS YP_001281300.1 148659777 5212138 complement(22995..24539) 1 NC_009525.1 serine/threonine phosphatase Ppp 24539 ppp 5212138 ppp Mycobacterium tuberculosis H37Ra serine/threonine phosphatase Ppp YP_001281300.1 22995 R 419947 CDS YP_001281301.1 148659778 5214159 complement(24628..25095) 1 NC_009525.1 hypothetical protein 25095 5214159 MRA_0021 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281301.1 24628 R 419947 CDS YP_001281302.1 148659779 5214160 complement(25219..26802) 1 NC_009525.1 hypothetical protein 26802 5214160 MRA_0022 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281302.1 25219 R 419947 CDS YP_001281303.1 148659780 5214162 complement(27271..28239) 1 NC_009525.1 2-nitropropane dioxygenase 28239 5214162 MRA_0023 Mycobacterium tuberculosis H37Ra 2-nitropropane dioxygenase YP_001281303.1 27271 R 419947 CDS YP_001281304.1 148659781 5214163 28351..28659 1 NC_009525.1 hypothetical protein 28659 5214163 MRA_0024 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281304.1 28351 D 419947 CDS YP_001281305.1 148659782 5214088 complement(28381..28800) 1 NC_009525.1 transcriptional regulatory protein whib-like WhiB5 28800 whiB5 5214088 whiB5 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein whib-like WhiB5 YP_001281305.1 28381 R 419947 CDS YP_001281306.1 148659783 5214089 28953..29723 1 NC_009525.1 transcriptional regulatory protein 29723 5214089 MRA_0026 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281306.1 28953 D 419947 CDS YP_001281307.1 148659784 5214090 29720..30565 1 NC_009525.1 NLP/P60 family protein 30565 5214090 MRA_0027 Mycobacterium tuberculosis H37Ra NLP/P60 family protein YP_001281307.1 29720 D 419947 CDS YP_001281308.1 148659785 5214091 30603..30965 1 NC_009525.1 hypothetical protein 30965 5214091 MRA_0028 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281308.1 30603 D 419947 CDS YP_001281309.1 148659786 5214092 31080..32426 1 NC_009525.1 hypothetical protein 32426 5214092 MRA_0029 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281309.1 31080 D 419947 CDS YP_001281310.1 148659787 5214093 32547..32864 1 NC_009525.1 hypothetical protein 32864 5214093 MRA_0030 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281310.1 32547 D 419947 CDS YP_001281311.1 148659788 5214094 32872..33177 1 NC_009525.1 hypothetical protein 33177 5214094 MRA_0031 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281311.1 32872 D 419947 CDS YP_001281312.1 148659789 5214834 33415..34512 1 NC_009525.1 hypothetical protein 34512 5214834 MRA_0032 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281312.1 33415 D 419947 CDS YP_001281313.1 148659790 5214835 34582..34911 1 NC_009525.1 hypothetical protein 34911 5214835 MRA_0033 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281313.1 34582 D 419947 CDS YP_001281314.1 148659791 5214836 34940..35152 1 NC_009525.1 remnant of a transposase 35152 5214836 MRA_0034 Mycobacterium tuberculosis H37Ra remnant of a transposase YP_001281314.1 34940 D 419947 CDS YP_001281315.1 148659792 5214837 35653..37968 1 NC_009525.1 8-amino-7-oxononanoate synthase 37968 bioF2 5214837 bioF2 Mycobacterium tuberculosis H37Ra 8-amino-7-oxononanoate synthase YP_001281315.1 35653 D 419947 CDS YP_001281316.1 148659793 5214838 37965..38228 1 NC_009525.1 acyl carrier protein 38228 acpA 5214838 acpA Mycobacterium tuberculosis H37Ra acyl carrier protein YP_001281316.1 37965 D 419947 CDS YP_001281317.1 148659794 5214839 38225..38620 1 NC_009525.1 hypothetical protein 38620 5214839 MRA_0037 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281317.1 38225 D 419947 CDS YP_001281318.1 148659795 5212838 38617..40305 1 NC_009525.1 fatty-acid--CoA ligase 40305 fadD34 5212838 fadD34 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001281318.1 38617 D 419947 CDS YP_001281319.1 148659796 5212839 complement(40414..41187) 1 NC_009525.1 hypothetical protein 41187 5212839 MRA_0039 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281319.1 40414 R 419947 CDS YP_001281320.1 148659797 5212840 complement(41235..42560) 1 NC_009525.1 integral membrane protein 42560 5212840 MRA_0040 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281320.1 41235 R 419947 CDS YP_001281321.1 148659798 5212841 42662..43270 1 NC_009525.1 hypothetical protein 43270 5212841 MRA_0041 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281321.1 42662 D 419947 CDS YP_001281322.1 148659799 5212842 complement(43362..43709) 1 NC_009525.1 transmembrane protein 43709 5212842 MRA_0042 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281322.1 43362 R 419947 CDS YP_001281323.1 148659800 5212843 complement(43791..44723) 1 NC_009525.1 hypothetical protein 44723 mtc28 5212843 mtc28 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281323.1 43791 R 419947 CDS YP_001281324.1 148659801 5212844 44920..47829 1 NC_009525.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 47829 leuS 5212844 leuS Mycobacterium tuberculosis H37Ra leucyl-tRNA synthetase YP_001281324.1 44920 D 419947 CDS YP_001281325.1 148659802 5212672 complement(47939..48565) 1 NC_009525.1 MarR family transcriptional regulator 48565 5212672 MRA_0045 Mycobacterium tuberculosis H37Ra MarR family transcriptional regulator YP_001281325.1 47939 R 419947 CDS YP_001281326.1 148659803 5212673 complement(48724..49458) 1 NC_009525.1 GntR family transcriptional regulator 49458 5212673 MRA_0046 Mycobacterium tuberculosis H37Ra GntR family transcriptional regulator YP_001281326.1 48724 R 419947 CDS YP_001281327.1 148659804 5212674 complement(49591..50385) 1 NC_009525.1 oxidoreductase 50385 5212674 MRA_0047 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281327.1 49591 R 419947 CDS YP_001281328.1 148659805 5212675 complement(50401..51297) 1 NC_009525.1 hydrolase 51297 5212675 MRA_0048 Mycobacterium tuberculosis H37Ra hydrolase YP_001281328.1 50401 R 419947 CDS YP_001281329.1 148659806 5212676 complement(51379..52482) 1 NC_009525.1 1L-myo-inositol-1-phosphate synthase 52482 ino1 5212676 ino1 Mycobacterium tuberculosis H37Ra 1L-myo-inositol-1-phosphate synthase YP_001281329.1 51379 R 419947 CDS YP_001281330.1 148659807 5212677 complement(52543..53085) 1 NC_009525.1 hypothetical protein 53085 5212677 MRA_0050 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281330.1 52543 R 419947 CDS YP_001281331.1 148659808 5214394 complement(53186..54055) 1 NC_009525.1 hypothetical protein 54055 5214394 MRA_0051 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281331.1 53186 R 419947 CDS YP_001281332.1 148659809 5214395 54189..54602 1 NC_009525.1 hypothetical protein 54602 5214395 MRA_0052 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281332.1 54189 D 419947 CDS YP_001281333.1 148659810 5214396 55021..57057 1 NC_009525.1 bifunctional penicillin-binding protein 1A/1B PonA1 57057 ponA1 5214396 ponA1 Mycobacterium tuberculosis H37Ra bifunctional penicillin-binding protein 1A/1B PonA1 YP_001281333.1 55021 D 419947 CDS YP_001281334.1 148659811 5214397 57054..58736 1 NC_009525.1 transmembrane protein 58736 5214397 MRA_0054 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281334.1 57054 D 419947 CDS YP_001281335.1 148659812 5214398 58768..59331 1 NC_009525.1 hypothetical protein 59331 5214398 MRA_0055 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281335.1 58768 D 419947 CDS YP_001281336.1 148659813 5214399 59550..59840 1 NC_009525.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 59840 rpsF 5214399 rpsF Mycobacterium tuberculosis H37Ra 30S ribosomal protein S6 YP_001281336.1 59550 D 419947 CDS YP_001281337.1 148659814 5214400 59944..60438 1 NC_009525.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 60438 ssb 5214400 ssb Mycobacterium tuberculosis H37Ra single-stranded DNA-binding protein YP_001281337.1 59944 D 419947 CDS YP_001281338.1 148659815 5212963 60480..60734 1 NC_009525.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 60734 rpsR 5212963 rpsR Mycobacterium tuberculosis H37Ra 30S ribosomal protein S18 YP_001281338.1 60480 D 419947 CDS YP_001281339.1 148659816 5212964 60767..61225 1 NC_009525.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 61225 rplI 5212964 rplI Mycobacterium tuberculosis H37Ra 50S ribosomal protein L9 YP_001281339.1 60767 D 419947 CDS YP_001281340.1 148659817 5212965 61254..61775 1 NC_009525.1 hypothetical protein 61775 5212965 MRA_0059A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281340.1 61254 D 419947 CDS YP_001281341.1 148659818 5212966 61754..64378 1 NC_009525.1 unwinds double stranded DNA; these Mycobacterial enzymes appear to contain inteins; replicative DNA helicase 64378 dnaB 5212966 dnaB Mycobacterium tuberculosis H37Ra replicative DNA helicase YP_001281341.1 61754 D 419947 CDS YP_001281342.1 148659819 5212967 64558..65250 1 NC_009525.1 hypothetical protein 65250 5212967 MRA_0061 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281342.1 64558 D 419947 CDS YP_001281343.1 148659820 5212968 65267..66325 1 NC_009525.1 hypothetical protein 66325 5212968 MRA_0062 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281343.1 65267 D 419947 CDS YP_001281344.1 148659821 5211956 66349..66774 1 NC_009525.1 hypothetical protein 66774 5211956 MRA_0063 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281344.1 66349 D 419947 CDS YP_001281345.1 148659822 5211957 66910..68052 1 NC_009525.1 cellulase 68052 celA1 5211957 celA1 Mycobacterium tuberculosis H37Ra cellulase YP_001281345.1 66910 D 419947 CDS YP_001281346.1 148659823 5211958 68281..69720 1 NC_009525.1 oxidoreductase 69720 5211958 MRA_0065 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281346.1 68281 D 419947 CDS YP_001281347.1 148659824 5211959 69978..72917 1 NC_009525.1 hypothetical protein 72917 5211959 MRA_0066 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281347.1 69978 D 419947 CDS YP_001281348.1 148659825 5211960 73179..73580 1 NC_009525.1 hypothetical protein 73580 5211960 MRA_0067 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281348.1 73179 D 419947 CDS YP_001281349.1 148659826 5211961 complement(73632..75869) 1 NC_009525.1 isocitrate dehydrogenase (NADP) Icd2 75869 icd2 5211961 icd2 Mycobacterium tuberculosis H37Ra isocitrate dehydrogenase (NADP) Icd2 YP_001281349.1 73632 R 419947 CDS YP_001281350.1 148659827 5211962 complement(75987..76556) 1 NC_009525.1 TetR family transcriptional regulator 76556 5211962 MRA_0069 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001281350.1 75987 R 419947 CDS YP_001281351.1 148659828 5211681 76659..77570 1 NC_009525.1 short chain dehydrogenase 77570 5211681 MRA_0070 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001281351.1 76659 D 419947 CDS YP_001281352.1 148659829 5211682 complement(77595..78980) 1 NC_009525.1 L-serine dehydratase 78980 sdaA 5211682 sdaA Mycobacterium tuberculosis H37Ra L-serine dehydratase YP_001281352.1 77595 R 419947 CDS YP_001281353.1 148659830 5211683 complement(78977..80254) 1 NC_009525.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 80254 glyA 5211683 glyA Mycobacterium tuberculosis H37Ra serine hydroxymethyltransferase YP_001281353.1 78977 R 419947 CDS YP_001281354.1 148659831 5211684 80844..81551 1 NC_009525.1 maturase 81551 5211684 MRA_0073 Mycobacterium tuberculosis H37Ra maturase YP_001281354.1 80844 D 419947 CDS YP_001281355.1 148659832 5211685 81982..83031 1 NC_009525.1 glutamine-transport transmembrane protein ABC transporter 83031 5211685 MRA_0074 Mycobacterium tuberculosis H37Ra glutamine-transport transmembrane protein ABC transporter YP_001281355.1 81982 D 419947 CDS YP_001281356.1 148659833 5211686 83034..84026 1 NC_009525.1 glutamine-transport ATP-binding protein ABC transporter GlnQ 84026 glnQ1 5211686 glnQ1 Mycobacterium tuberculosis H37Ra glutamine-transport ATP-binding protein ABC transporter GlnQ YP_001281356.1 83034 D 419947 CDS YP_001281357.1 148659834 5211675 84106..85341 1 NC_009525.1 hypothetical protein 85341 5211675 MRA_0076 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281357.1 84106 D 419947 CDS YP_001281358.1 148659835 5211676 85354..86526 1 NC_009525.1 aminotransferase 86526 5211676 MRA_0077 Mycobacterium tuberculosis H37Ra aminotransferase YP_001281358.1 85354 D 419947 CDS YP_001281359.1 148659836 5211677 complement(86541..86930) 1 NC_009525.1 hypothetical protein 86930 5211677 MRA_0078 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281359.1 86541 R 419947 CDS YP_001281360.1 148659837 5211678 complement(86994..87824) 1 NC_009525.1 oxidoreductase 87824 5211678 MRA_0079 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281360.1 86994 R 419947 CDS YP_001281361.1 148659838 5211679 87886..88491 1 NC_009525.1 transcriptional regulatory protein 88491 5211679 MRA_0080 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281361.1 87886 D 419947 CDS YP_001281362.1 148659839 5211680 complement(88566..89159) 1 NC_009525.1 hypothetical protein 89159 5211680 MRA_0081 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281362.1 88566 R 419947 CDS YP_001281363.1 148659840 5214937 complement(89156..89362) 1 NC_009525.1 hypothetical protein 89362 5214937 MRA_0082 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281363.1 89156 R 419947 CDS YP_001281364.1 148659841 5214938 89562..90383 1 NC_009525.1 hypothetical protein 90383 5214938 MRA_0083 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281364.1 89562 D 419947 CDS YP_001281365.1 148659842 5214939 90380..90838 1 NC_009525.1 hypothetical protein 90838 5214939 MRA_0084 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281365.1 90380 D 419947 CDS YP_001281366.1 148659843 5214940 90933..91277 1 NC_009525.1 transcriptional regulatory protein 91277 5214940 MRA_0085 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281366.1 90933 D 419947 CDS YP_001281367.1 148659844 5214941 91282..91761 1 NC_009525.1 oxidoreductase 91761 5214941 MRA_0086 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281367.1 91282 D 419947 CDS YP_001281368.1 148659845 5214942 91758..93680 1 NC_009525.1 NADH-ubiquinone oxidoreductase 93680 5214942 MRA_0087 Mycobacterium tuberculosis H37Ra NADH-ubiquinone oxidoreductase YP_001281368.1 91758 D 419947 CDS YP_001281369.1 148659846 5214943 93686..94636 1 NC_009525.1 formate hydrogenlyase HycD 94636 hycD 5214943 hycD Mycobacterium tuberculosis H37Ra formate hydrogenlyase HycD YP_001281369.1 93686 D 419947 CDS YP_001281370.1 148659847 5215385 94647..95309 1 NC_009525.1 hydrogenase HycP 95309 hycP 5215385 hycP Mycobacterium tuberculosis H37Ra hydrogenase HycP YP_001281370.1 94647 D 419947 CDS YP_001281371.1 148659848 5215386 95309..96775 1 NC_009525.1 hydrogenase HycQ 96775 hycQ 5215386 hycQ Mycobacterium tuberculosis H37Ra hydrogenase HycQ YP_001281371.1 95309 D 419947 CDS YP_001281372.1 148659849 5215387 96772..98250 1 NC_009525.1 formate hydrogenase HycE 98250 hycE 5215387 hycE Mycobacterium tuberculosis H37Ra formate hydrogenase HycE YP_001281372.1 96772 D 419947 CDS YP_001281373.1 148659850 5215388 98285..98959 1 NC_009525.1 hypothetical protein 98959 5215388 MRA_0092 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281373.1 98285 D 419947 CDS YP_001281374.1 148659851 5215389 99116..99709 1 NC_009525.1 methyltransferase 99709 5215389 MRA_0093 Mycobacterium tuberculosis H37Ra methyltransferase YP_001281374.1 99116 D 419947 CDS YP_001281375.1 148659852 5215390 99838..100608 1 NC_009525.1 hypothetical protein 100608 5215390 MRA_0094 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281375.1 99838 D 419947 CDS YP_001281376.1 148659853 5214854 101042..101809 1 NC_009525.1 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase 101809 mtn 5214854 mtn Mycobacterium tuberculosis H37Ra 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase YP_001281376.1 101042 D 419947 CDS YP_001281377.1 148659854 5214855 101941..104226 1 NC_009525.1 cation transporter p-type ATPase A 104226 ctpA 5214855 ctpA Mycobacterium tuberculosis H37Ra cation transporter p-type ATPase A YP_001281377.1 101941 D 419947 CDS YP_001281378.1 148659855 5214856 complement(104173..105021) 1 NC_009525.1 hypothetical protein 105021 5214856 MRA_0097 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281378.1 104173 R 419947 CDS YP_001281379.1 148659856 5214857 complement(105068..106021) 1 NC_009525.1 hypothetical protein 106021 5214857 MRA_0098 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281379.1 105068 R 419947 CDS YP_001281380.1 148659857 5214858 complement(106163..106573) 1 NC_009525.1 hypothetical protein 106573 5214858 MRA_0099 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281380.1 106163 R 419947 CDS YP_001281381.1 148659858 5214859 106682..108073 1 NC_009525.1 PPE family protein 108073 5214859 MRA_0100 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281381.1 106682 D 419947 CDS YP_001281382.1 148659859 5214860 108092..108961 1 NC_009525.1 dioxygenase 108961 5214860 MRA_0101 Mycobacterium tuberculosis H37Ra dioxygenase YP_001281382.1 108092 D 419947 CDS YP_001281383.1 148659860 5214243 108958..109509 1 NC_009525.1 hypothetical protein 109509 5214243 MRA_0102 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281383.1 108958 D 419947 CDS YP_001281384.1 148659861 5214244 109514..111136 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 111136 fadD10 5214244 fadD10 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001281384.1 109514 D 419947 CDS YP_001281385.1 148659862 5214245 111141..111377 1 NC_009525.1 hypothetical protein 111377 5214245 MRA_0104 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281385.1 111141 D 419947 CDS YP_001281386.1 148659863 5214246 111359..111637 1 NC_009525.1 peptide synthetase 111637 nrp1 5214246 nrp1 Mycobacterium tuberculosis H37Ra peptide synthetase YP_001281386.1 111359 D 419947 CDS YP_001281387.1 148659864 5214247 111665..118897 1 NC_009525.1 peptide synthetase 118897 nrp2 5214247 nrp2 Mycobacterium tuberculosis H37Ra peptide synthetase YP_001281387.1 111665 D 419947 CDS YP_001281388.1 148659865 5214248 119072..121057 1 NC_009525.1 integral membrane protein 121057 5214248 MRA_0107 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281388.1 119072 D 419947 CDS YP_001281389.1 148659866 5213350 complement(121273..123531) 1 NC_009525.1 cation-transporting P-type ATPase B 123531 ctpB 5213350 ctpB Mycobacterium tuberculosis H37Ra cation-transporting P-type ATPase B YP_001281389.1 121273 R 419947 CDS YP_001281390.1 148659867 5213351 123675..125189 1 NC_009525.1 hypothetical protein 125189 5213351 MRA_0109 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281390.1 123675 D 419947 CDS YP_001281391.1 148659868 5213352 complement(125338..125622) 1 NC_009525.1 required for 70S ribosome assembly; 50S ribosomal protein L28 125622 rpmB 5213352 rpmB Mycobacterium tuberculosis H37Ra 50S ribosomal protein L28 YP_001281391.1 125338 R 419947 CDS YP_001281392.1 148659869 5213353 125732..126928 1 NC_009525.1 hypothetical protein 126928 5213353 MRA_0111 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281392.1 125732 D 419947 CDS YP_001281393.1 148659870 5213354 complement(127001..131899) 1 NC_009525.1 cation-transporter ATPase I CtpI 131899 ctpI2 5213354 ctpI2 Mycobacterium tuberculosis H37Ra cation-transporter ATPase I CtpI YP_001281393.1 127001 R 419947 CDS YP_001281394.1 148659871 5213355 complement(132253..132462) 1 NC_009525.1 hypothetical protein 132462 5213355 MRA_0114 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281394.1 132253 R 419947 CDS YP_001281395.1 148659872 5213356 132741..134231 1 NC_009525.1 PE-PGRS family protein 134231 5213356 MRA_0115 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001281395.1 132741 D 419947 CDS YP_001281396.1 148659873 5214710 134379..135128 1 NC_009525.1 rhomboid family protein 135128 5214710 MRA_0116 Mycobacterium tuberculosis H37Ra rhomboid family protein YP_001281396.1 134379 D 419947 CDS YP_001281397.1 148659874 5214711 135309..137366 1 NC_009525.1 transmembrane acyltransferase 137366 5214711 MRA_0117 Mycobacterium tuberculosis H37Ra transmembrane acyltransferase YP_001281397.1 135309 D 419947 CDS YP_001281398.1 148659875 5214712 137648..138604 1 NC_009525.1 GDP-D-mannose dehydratase 138604 gca 5214712 gca Mycobacterium tuberculosis H37Ra GDP-D-mannose dehydratase YP_001281398.1 137648 D 419947 CDS YP_001281399.1 148659876 5214713 138678..139268 1 NC_009525.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 139268 gmhA 5214713 gmhA Mycobacterium tuberculosis H37Ra phosphoheptose isomerase YP_001281399.1 138678 D 419947 CDS YP_001281400.1 148659877 5214714 139300..139872 1 NC_009525.1 D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB 139872 gmhB 5214714 gmhB Mycobacterium tuberculosis H37Ra D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB YP_001281400.1 139300 D 419947 CDS YP_001281401.1 148659878 5214715 139872..141032 1 NC_009525.1 D-alpha-D-heptose-7-phosphate kinase HddA 141032 hddA 5214715 hddA Mycobacterium tuberculosis H37Ra D-alpha-D-heptose-7-phosphate kinase HddA YP_001281401.1 139872 D 419947 CDS YP_001281402.1 148659879 5214492 141324..141503 1 NC_009525.1 hypothetical protein 141503 5214492 MRA_0122 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281402.1 141324 D 419947 CDS YP_001281403.1 148659880 5214493 complement(141626..142381) 1 NC_009525.1 hypothetical protein 142381 5214493 MRA_0123 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281403.1 141626 R 419947 CDS YP_001281404.1 148659881 5214494 142559..143503 1 NC_009525.1 oxidative stress response regulatory protein OxyS 143503 oxyS 5214494 oxyS Mycobacterium tuberculosis H37Ra oxidative stress response regulatory protein OxyS YP_001281404.1 142559 D 419947 CDS YP_001281405.1 148659882 5214495 complement(143487..145235) 1 NC_009525.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 145235 5214495 MRA_0125 Mycobacterium tuberculosis H37Ra oxalyl-CoA decarboxylase YP_001281405.1 143487 R 419947 CDS YP_001281406.1 148659883 5214496 145408..146985 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 146985 fadD7 5214496 fadD7 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001281406.1 145408 D 419947 CDS YP_001281407.1 148659884 5214497 complement(146986..149130) 1 NC_009525.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 149130 fusA2 5214497 fusA2 Mycobacterium tuberculosis H37Ra elongation factor G YP_001281407.1 146986 R 419947 CDS YP_001281408.1 148659885 5214498 complement(149267..149701) 1 NC_009525.1 hypothetical protein 149701 5214498 MRA_0128 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281408.1 149267 R 419947 CDS YP_001281409.1 148659886 5214017 149850..150218 1 NC_009525.1 hypothetical protein 150218 5214017 MRA_0129 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281409.1 149850 D 419947 CDS YP_001281410.1 148659887 5214018 150215..150583 1 NC_009525.1 hypothetical protein 150583 5214018 MRA_0130 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281410.1 150215 D 419947 CDS YP_001281411.1 148659888 5214019 150892..152355 1 NC_009525.1 PE-PGRS family protein 152355 5214019 MRA_0131 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001281411.1 150892 D 419947 CDS YP_001281412.1 148659889 5214020 152507..153574 1 NC_009525.1 serine protease 153574 pepA 5214020 pepA Mycobacterium tuberculosis H37Ra serine protease YP_001281412.1 152507 D 419947 CDS YP_001281413.1 148659890 5214021 153683..155488 1 NC_009525.1 trehalose synthase TreS 155488 treS 5214021 treS Mycobacterium tuberculosis H37Ra trehalose synthase TreS YP_001281413.1 153683 D 419947 CDS YP_001281414.1 148659891 5214022 155591..156958 1 NC_009525.1 hypothetical protein 156958 5214022 MRA_0134 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281414.1 155591 D 419947 CDS YP_001281415.1 148659892 5211979 157026..157805 1 NC_009525.1 transmembrane protein 157805 5211979 MRA_0135 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281415.1 157026 D 419947 CDS YP_001281416.1 148659893 5211980 complement(157937..158959) 1 NC_009525.1 secreted antigen 86-C FbpC 158959 fbpC 5211980 fbpC Mycobacterium tuberculosis H37Ra secreted antigen 86-C FbpC YP_001281416.1 157937 R 419947 CDS YP_001281417.1 148659894 5211981 159206..159661 1 NC_009525.1 hypothetical protein 159661 5211981 MRA_0137 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281417.1 159206 D 419947 CDS YP_001281418.1 148659895 5211982 complement(159674..161017) 1 NC_009525.1 acyl-CoA dehydrogenase 161017 fadE1 5211982 fadE1 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001281418.1 159674 R 419947 CDS YP_001281419.1 148659896 5211983 complement(161059..162141) 1 NC_009525.1 f420-dependent glucose-6-phosphate dehydrogenase Fgd2 162141 fgd2 5211983 fgd2 Mycobacterium tuberculosis H37Ra f420-dependent glucose-6-phosphate dehydrogenase Fgd2 YP_001281419.1 161059 R 419947 CDS YP_001281420.1 148659897 5211984 162228..162833 1 NC_009525.1 puromycin N-acetyltransferase 162833 5211984 MRA_0140 Mycobacterium tuberculosis H37Ra puromycin N-acetyltransferase YP_001281420.1 162228 D 419947 CDS YP_001281421.1 148659898 5211985 163130..164032 1 NC_009525.1 epoxide hydrolase 164032 ephF 5211985 ephF Mycobacterium tuberculosis H37Ra epoxide hydrolase YP_001281421.1 163130 D 419947 CDS YP_001281422.1 148659899 5211860 complement(164003..164608) 1 NC_009525.1 transcriptional regulatory protein 164608 5211860 MRA_0142 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281422.1 164003 R 419947 CDS YP_001281423.1 148659900 5211861 164725..166050 1 NC_009525.1 cytochrome p450 138 CYP138 166050 cyp138 5211861 cyp138 Mycobacterium tuberculosis H37Ra cytochrome p450 138 CYP138 YP_001281423.1 164725 D 419947 CDS YP_001281424.1 148659901 5211862 complement(166071..166619) 1 NC_009525.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 166619 msrA 5211862 msrA Mycobacterium tuberculosis H37Ra methionine sulfoxide reductase A YP_001281424.1 166071 R 419947 CDS YP_001281425.1 148659902 5211863 166682..167185 1 NC_009525.1 hypothetical protein 167185 5211863 MRA_0145 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281425.1 166682 D 419947 CDS YP_001281426.1 148659903 5211864 167186..168208 1 NC_009525.1 dihydroflavonol 4-reductase-related protein 168208 5211864 MRA_0146 Mycobacterium tuberculosis H37Ra dihydroflavonol 4-reductase-related protein YP_001281426.1 167186 D 419947 CDS YP_001281427.1 148659904 5211865 168269..168649 1 NC_009525.1 hypothetical protein 168649 5211865 MRA_0147 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281427.1 168269 D 419947 CDS YP_001281428.1 148659905 5215626 complement(168630..169040) 1 NC_009525.1 hypothetical protein 169040 5215626 MRA_0148 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281428.1 168630 R 419947 CDS YP_001281429.1 148659906 5215627 169070..169996 1 NC_009525.1 hypothetical protein 169996 5215627 MRA_0149 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281429.1 169070 D 419947 CDS YP_001281430.1 148659907 5215628 complement(170063..171541) 1 NC_009525.1 chloride channel 171541 5215628 MRA_0150 Mycobacterium tuberculosis H37Ra chloride channel YP_001281430.1 170063 R 419947 CDS YP_001281431.1 148659908 5215629 171643..172485 1 NC_009525.1 TetR family transcriptional regulator 172485 5215629 MRA_0151 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001281431.1 171643 D 419947 CDS YP_001281432.1 148659909 5215630 172574..173527 1 NC_009525.1 hypothetical protein 173527 5215630 MRA_0152 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281432.1 172574 D 419947 CDS YP_001281433.1 148659910 5215631 173570..174502 1 NC_009525.1 hypothetical protein 174502 5215631 MRA_0153 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281433.1 173570 D 419947 CDS YP_001281434.1 148659911 5215632 174597..176117 1 NC_009525.1 aldehyde dehydrogenase (NAD+) dependent 176117 5215632 MRA_0154 Mycobacterium tuberculosis H37Ra aldehyde dehydrogenase (NAD+) dependent YP_001281434.1 174597 D 419947 CDS YP_001281435.1 148659912 5215491 176192..177052 1 NC_009525.1 short-chain type dehydrogenase/reductase 177052 5215491 MRA_0155 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001281435.1 176192 D 419947 CDS YP_001281436.1 148659913 5215492 177059..178027 1 NC_009525.1 quinone oxidoreductase 178027 5215492 MRA_0156 Mycobacterium tuberculosis H37Ra quinone oxidoreductase YP_001281436.1 177059 D 419947 CDS YP_001281437.1 148659914 5215493 complement(178024..178311) 1 NC_009525.1 hypothetical protein 178311 5215493 MRA_0157 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281437.1 178024 R 419947 CDS YP_001281438.1 148659915 5215494 complement(178903..180669) 1 NC_009525.1 PE family protein 180669 5215494 MRA_0158 Mycobacterium tuberculosis H37Ra PE family protein YP_001281438.1 178903 R 419947 CDS YP_001281439.1 148659916 5215495 complement(180679..182256) 1 NC_009525.1 PE family protein 182256 5215495 MRA_0159 Mycobacterium tuberculosis H37Ra PE family protein YP_001281439.1 180679 R 419947 CDS YP_001281440.1 148659917 5215496 complement(182515..183345) 1 NC_009525.1 phosphotyrosine protein phosphatase PtpB 183345 ptbB 5215496 ptbB Mycobacterium tuberculosis H37Ra phosphotyrosine protein phosphatase PtpB YP_001281440.1 182515 R 419947 CDS YP_001281441.1 148659918 5214374 complement(183347..184558) 1 NC_009525.1 acyl-CoA dehydrogenase 184558 fadE2 5214374 fadE2 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001281441.1 183347 R 419947 CDS YP_001281442.1 148659919 5214375 184982..186082 1 NC_009525.1 NAD(P) transhydrogenase subunit alpha PntAa 186082 pntAa 5214375 pntAa Mycobacterium tuberculosis H37Ra NAD(P) transhydrogenase subunit alpha PntAa YP_001281442.1 184982 D 419947 CDS YP_001281443.1 148659920 5214376 186083..186415 1 NC_009525.1 NAD(P) transhydrogenase subunit alpha PntAb 186415 pntAb 5214376 pntAb Mycobacterium tuberculosis H37Ra NAD(P) transhydrogenase subunit alpha PntAb YP_001281443.1 186083 D 419947 CDS YP_001281444.1 148659921 5214377 186412..187839 1 NC_009525.1 NAD(P) transhydrogenase subunit beta 187839 pntB 5214377 pntB Mycobacterium tuberculosis H37Ra NAD(P) transhydrogenase subunit beta YP_001281444.1 186412 D 419947 CDS YP_001281445.1 148659922 5214378 188145..188789 1 NC_009525.1 TetR family transcriptional regulator 188789 5214378 MRA_0166 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001281445.1 188145 D 419947 CDS YP_001281446.1 148659923 5214379 complement(188793..190199) 1 NC_009525.1 PE family protein 190199 5214379 MRA_0167 Mycobacterium tuberculosis H37Ra PE family protein YP_001281446.1 188793 R 419947 CDS YP_001281447.1 148659924 5214380 complement(190291..191799) 1 NC_009525.1 PE family protein 191799 5214380 MRA_0168 Mycobacterium tuberculosis H37Ra PE family protein YP_001281447.1 190291 R 419947 CDS YP_001281448.1 148659925 5212233 191967..193316 1 NC_009525.1 oxidoreductase 193316 5212233 MRA_0169 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281448.1 191967 D 419947 CDS YP_001281449.1 148659926 5212234 complement(193344..194495) 1 NC_009525.1 zinc-type alcohol dehydrogenase subunit E 194495 adhE1 5212234 adhE1 Mycobacterium tuberculosis H37Ra zinc-type alcohol dehydrogenase subunit E YP_001281449.1 193344 R 419947 CDS YP_001281450.1 148659927 5212235 194477..194932 1 NC_009525.1 hypothetical protein 194932 5212235 MRA_0171 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281450.1 194477 D 419947 CDS YP_001281451.1 148659928 5212236 194986..195471 1 NC_009525.1 hypothetical protein 195471 5212236 MRA_0172 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281451.1 194986 D 419947 CDS YP_001281452.1 148659929 5212237 complement(195504..196298) 1 NC_009525.1 MarR family transcriptional regulator 196298 5212237 MRA_0173 Mycobacterium tuberculosis H37Ra MarR family transcriptional regulator YP_001281452.1 195504 R 419947 CDS YP_001281453.1 148659930 5212238 196353..198017 1 NC_009525.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 198017 fadD5 5212238 fadD5 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--CoA ligase YP_001281453.1 196353 D 419947 CDS YP_001281454.1 148659931 5215106 198221..199018 1 NC_009525.1 hypothetical protein 199018 yrbE1A 5215106 yrbE1A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281454.1 198221 D 419947 CDS YP_001281455.1 148659932 5215107 199020..199889 1 NC_009525.1 hypothetical protein 199889 yrbE1B 5215107 yrbE1B Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281455.1 199020 D 419947 CDS YP_001281456.1 148659933 5215108 199894..201258 1 NC_009525.1 MCE-family protein Mce1A 201258 mce1A 5215108 mce1A Mycobacterium tuberculosis H37Ra MCE-family protein Mce1A YP_001281456.1 199894 D 419947 CDS YP_001281457.1 148659934 5215109 201255..202295 1 NC_009525.1 MCE-family protein Mce1B 202295 mce1B 5215109 mce1B Mycobacterium tuberculosis H37Ra MCE-family protein Mce1B YP_001281457.1 201255 D 419947 CDS YP_001281458.1 148659935 5215110 202292..203839 1 NC_009525.1 MCE-family protein Mce1C 203839 mce1C 5215110 mce1C Mycobacterium tuberculosis H37Ra MCE-family protein Mce1C YP_001281458.1 202292 D 419947 CDS YP_001281459.1 148659936 5215111 203836..205428 1 NC_009525.1 MCE-family protein Mce1D 205428 mce1D 5215111 mce1D Mycobacterium tuberculosis H37Ra MCE-family protein Mce1D YP_001281459.1 203836 D 419947 CDS YP_001281460.1 148659937 5215112 205425..206597 1 NC_009525.1 MCE family lipoprotein LprK 206597 lprK 5215112 lprK Mycobacterium tuberculosis H37Ra MCE family lipoprotein LprK YP_001281460.1 205425 D 419947 CDS YP_001281461.1 148659938 5215134 206591..208138 1 NC_009525.1 MCE-family protein Mce1F 208138 mce1F 5215134 mce1F Mycobacterium tuberculosis H37Ra MCE-family protein Mce1F YP_001281461.1 206591 D 419947 CDS YP_001281462.1 148659939 5215135 208174..208815 1 NC_009525.1 Mce associated membrane protein 208815 5215135 MRA_0183 Mycobacterium tuberculosis H37Ra Mce associated membrane protein YP_001281462.1 208174 D 419947 CDS YP_001281463.1 148659940 5215136 208818..209780 1 NC_009525.1 Mce associated transmembrane protein 209780 5215136 MRA_0184 Mycobacterium tuberculosis H37Ra Mce associated transmembrane protein YP_001281463.1 208818 D 419947 CDS YP_001281464.1 148659941 5215137 209777..210331 1 NC_009525.1 Mce associated protein 210331 5215137 MRA_0185 Mycobacterium tuberculosis H37Ra Mce associated protein YP_001281464.1 209777 D 419947 CDS YP_001281465.1 148659942 5215138 210298..211032 1 NC_009525.1 Mce associated membrane protein 211032 5215138 MRA_0186 Mycobacterium tuberculosis H37Ra Mce associated membrane protein YP_001281465.1 210298 D 419947 CDS YP_001281466.1 148659943 5215139 complement(211063..212172) 1 NC_009525.1 lipoprotein LprO 212172 lprO 5215139 lprO Mycobacterium tuberculosis H37Ra lipoprotein LprO YP_001281466.1 211063 R 419947 CDS YP_001281467.1 148659944 5215270 complement(212252..213610) 1 NC_009525.1 transmembrane protein 213610 5215270 MRA_0188 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281467.1 212252 R 419947 CDS YP_001281468.1 148659945 5215271 complement(213637..214371) 1 NC_009525.1 hypothetical protein 214371 5215271 MRA_0189 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281468.1 213637 R 419947 CDS YP_001281469.1 148659946 5215272 complement(214388..215500) 1 NC_009525.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 215500 sigG 5215272 sigG Mycobacterium tuberculosis H37Ra RNA polymerase factor sigma-70 YP_001281469.1 214388 R 419947 CDS YP_001281470.1 148659947 5215273 215448..216287 1 NC_009525.1 lysophospholipase 216287 5215273 MRA_0191 Mycobacterium tuberculosis H37Ra lysophospholipase YP_001281470.1 215448 D 419947 CDS YP_001281471.1 148659948 5215274 216329..217078 1 NC_009525.1 hypothetical protein 217078 5215274 MRA_0192 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281471.1 216329 D 419947 CDS YP_001281472.1 148659949 5215275 217075..217584 1 NC_009525.1 hypothetical protein 217584 5215275 MRA_0193 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281472.1 217075 D 419947 CDS YP_001281473.1 148659950 5215276 217629..219704 1 NC_009525.1 beta-glucosidase 219704 bglS 5215276 bglS Mycobacterium tuberculosis H37Ra beta-glucosidase YP_001281473.1 217629 D 419947 CDS YP_001281474.1 148659951 5215560 220065..220727 1 NC_009525.1 O-methyltransferase 220727 5215560 MRA_0195 Mycobacterium tuberculosis H37Ra O-methyltransferase YP_001281474.1 220065 D 419947 CDS YP_001281475.1 148659952 5215561 220846..221277 1 NC_009525.1 transmembrane protein 221277 5215561 MRA_0196 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281475.1 220846 D 419947 CDS YP_001281476.1 148659953 5215562 complement(221356..223083) 1 NC_009525.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 223083 ilvD 5215562 ilvD Mycobacterium tuberculosis H37Ra dihydroxy-acid dehydratase YP_001281476.1 221356 R 419947 CDS YP_001281477.1 148659954 5215563 223231..223521 1 NC_009525.1 hypothetical protein 223521 5215563 MRA_0198 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281477.1 223231 D 419947 CDS YP_001281478.1 148659955 5215564 223649..224890 1 NC_009525.1 integral membrane protein 224890 5215564 MRA_0199 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281478.1 223649 D 419947 CDS YP_001281479.1 148659956 5215565 224924..226024 1 NC_009525.1 hypothetical protein 226024 5215565 MRA_0200 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281479.1 224924 D 419947 CDS YP_001281480.1 148659957 5212328 complement(226084..227931) 1 NC_009525.1 hypothetical protein 227931 5212328 MRA_0201 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281480.1 226084 R 419947 CDS YP_001281481.1 148659958 5212329 228238..231822 1 NC_009525.1 drugs ABC transporter ATP-binding protein 231822 5212329 MRA_0202 Mycobacterium tuberculosis H37Ra drugs ABC transporter ATP-binding protein YP_001281481.1 228238 D 419947 CDS YP_001281482.1 148659959 5212330 232259..232894 1 NC_009525.1 LuxR family transcriptional regulator 232894 5212330 MRA_0203 Mycobacterium tuberculosis H37Ra LuxR family transcriptional regulator YP_001281482.1 232259 D 419947 CDS YP_001281483.1 148659960 5212331 233007..233591 1 NC_009525.1 transcriptional regulatory protein 233591 5212331 MRA_0204 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281483.1 233007 D 419947 CDS YP_001281484.1 148659961 5212332 233591..235837 1 NC_009525.1 oxidoreductase 235837 5212332 MRA_0205 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281484.1 233591 D 419947 CDS YP_001281485.1 148659962 5212333 complement(235878..237869) 1 NC_009525.1 zinc metalloprotease 237869 5212333 MRA_0206 Mycobacterium tuberculosis H37Ra zinc metalloprotease YP_001281485.1 235878 R 419947 CDS YP_001281486.1 148659963 5212334 237912..238571 1 NC_009525.1 hypothetical protein 238571 5212334 MRA_0207 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281486.1 237912 D 419947 CDS YP_001281487.1 148659964 5212261 238568..239257 1 NC_009525.1 transmembrane protein 239257 5212261 MRA_0208 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281487.1 238568 D 419947 CDS YP_001281488.1 148659965 5212262 complement(239254..239757) 1 NC_009525.1 hypothetical protein 239757 5212262 MRA_0209 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281488.1 239254 R 419947 CDS YP_001281489.1 148659966 5212263 complement(239754..242654) 1 NC_009525.1 membrane protein MmpL11 242654 mmpL11 5212263 mmpL11 Mycobacterium tuberculosis H37Ra membrane protein MmpL11 YP_001281489.1 239754 R 419947 CDS YP_001281490.1 148659967 5212264 242876..243286 1 NC_009525.1 hypothetical protein 243286 5212264 MRA_0211 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281490.1 242876 D 419947 CDS YP_001281491.1 148659968 5212265 complement(243338..244621) 1 NC_009525.1 transmembrane protein 244621 5212265 MRA_0212 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281491.1 243338 R 419947 CDS YP_001281492.1 148659969 5212266 244746..245849 1 NC_009525.1 transmembrane protein 245849 5212266 MRA_0213 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281492.1 244746 D 419947 CDS YP_001281493.1 148659970 5215140 complement(245846..248680) 1 NC_009525.1 transmembrane transport protein MmpL3 248680 mmpL3 5215140 mmpL3 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL3 YP_001281493.1 245846 R 419947 CDS YP_001281494.1 148659971 5215141 complement(248746..249474) 1 NC_009525.1 hypothetical protein 249474 5215141 MRA_0215 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281494.1 248746 R 419947 CDS YP_001281495.1 148659972 5215142 complement(249477..250268) 1 NC_009525.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 250268 trmB 5215142 trmB Mycobacterium tuberculosis H37Ra tRNA (guanine-N(7)-)-methyltransferase YP_001281495.1 249477 R 419947 CDS YP_001281496.1 148659973 5215143 250400..251485 1 NC_009525.1 hypothetical protein 251485 5215143 MRA_0217 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281496.1 250400 D 419947 CDS YP_001281497.1 148659974 5215144 251482..252960 1 NC_009525.1 hypothetical protein 252960 5215144 MRA_0218 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281497.1 251482 D 419947 CDS YP_001281498.1 148659975 5215145 253144..254964 1 NC_009525.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 254964 pckA 5215145 pckA Mycobacterium tuberculosis H37Ra phosphoenolpyruvate carboxykinase YP_001281498.1 253144 D 419947 CDS YP_001281499.1 148659976 5215146 complement(255031..256002) 1 NC_009525.1 transcriptional regulatory protein NadR 256002 nadR 5215146 nadR Mycobacterium tuberculosis H37Ra transcriptional regulatory protein NadR YP_001281499.1 255031 R 419947 CDS YP_001281500.1 148659977 5214031 complement(255999..257312) 1 NC_009525.1 methyltransferase 257312 5214031 MRA_0221 Mycobacterium tuberculosis H37Ra methyltransferase YP_001281500.1 255999 R 419947 CDS YP_001281501.1 148659978 5214032 257426..259039 1 NC_009525.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 259039 fadD4 5214032 fadD4 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--CoA ligase YP_001281501.1 257426 D 419947 CDS YP_001281502.1 148659979 5214033 complement(259145..260218) 1 NC_009525.1 acyl-CoA dehydrogenase 260218 fadE3 5214033 fadE3 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001281502.1 259145 R 419947 CDS YP_001281503.1 148659980 5214034 260275..261288 1 NC_009525.1 hypothetical protein 261288 5214034 MRA_0224 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281503.1 260275 D 419947 CDS YP_001281504.1 148659981 5214035 complement(261285..262193) 1 NC_009525.1 esterase LipW 262193 lipW 5214035 lipW Mycobacterium tuberculosis H37Ra esterase LipW YP_001281504.1 261285 R 419947 CDS YP_001281505.1 148659982 5214036 262286..263614 1 NC_009525.1 transmembrane protein 263614 5214036 MRA_0226 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281505.1 262286 D 419947 CDS YP_001281506.1 148659983 5213059 263616..264164 1 NC_009525.1 transmembrane protein 264164 5213059 MRA_0227 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281506.1 263616 D 419947 CDS YP_001281507.1 148659984 5213060 264174..265385 1 NC_009525.1 esterase 265385 lipC 5213060 lipC Mycobacterium tuberculosis H37Ra esterase YP_001281507.1 264174 D 419947 CDS YP_001281508.1 148659985 5213061 265429..266838 1 NC_009525.1 hypothetical protein 266838 5213061 MRA_0229 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281508.1 265429 D 419947 CDS YP_001281509.1 148659986 5213062 266869..267657 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 267657 echA1 5213062 echA1 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001281509.1 266869 D 419947 CDS YP_001281510.1 148659987 5213063 complement(267663..269126) 1 NC_009525.1 aldehyde dehydrogenase 269126 5213063 MRA_0231 Mycobacterium tuberculosis H37Ra aldehyde dehydrogenase YP_001281510.1 267663 R 419947 CDS YP_001281511.1 148659988 5213064 complement(269225..269989) 1 NC_009525.1 methyltransferase 269989 5213064 MRA_0232 Mycobacterium tuberculosis H37Ra methyltransferase YP_001281511.1 269225 R 419947 CDS YP_001281512.1 148659989 5213065 270025..271179 1 NC_009525.1 glycosyltransferase 271179 5213065 MRA_0233 Mycobacterium tuberculosis H37Ra glycosyltransferase YP_001281512.1 270025 D 419947 CDS YP_001281513.1 148659990 5212532 complement(271196..272926) 1 NC_009525.1 transmembrane protein 272926 5212532 MRA_0234 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281513.1 271196 R 419947 CDS YP_001281514.1 148659991 5212533 complement(272936..274201) 1 NC_009525.1 hypothetical protein 274201 5212533 MRA_0235 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281514.1 272936 R 419947 CDS YP_001281515.1 148659992 5212534 274417..275640 1 NC_009525.1 integral membrane acyltransferase 275640 5212534 MRA_0236 Mycobacterium tuberculosis H37Ra integral membrane acyltransferase YP_001281515.1 274417 D 419947 CDS YP_001281516.1 148659993 5212535 complement(275668..276348) 1 NC_009525.1 hypothetical protein 276348 5212535 MRA_0237 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281516.1 275668 R 419947 CDS YP_001281517.1 148659994 5212536 complement(276345..277325) 1 NC_009525.1 parathion hydrolase; phosphotriesterase 277325 php 5212536 php Mycobacterium tuberculosis H37Ra phosphotriesterase YP_001281517.1 276345 R 419947 CDS YP_001281518.1 148659995 5212537 277420..279126 1 NC_009525.1 acyl-CoA dehydrogenase 279126 fadE4 5212537 fadE4 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001281518.1 277420 D 419947 CDS YP_001281519.1 148659996 5214188 279261..279950 1 NC_009525.1 TetR/AcrR-family transcriptional regulator 279950 5214188 MRA_0240 Mycobacterium tuberculosis H37Ra TetR/AcrR-family transcriptional regulator YP_001281519.1 279261 D 419947 CDS YP_001281520.1 148659997 5214189 279947..280891 1 NC_009525.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit beta 280891 nrdB 5214189 nrdB Mycobacterium tuberculosis H37Ra ribonucleotide-diphosphate reductase subunit beta YP_001281520.1 279947 D 419947 CDS YP_001281521.1 148659998 5214190 complement(280967..282502) 1 NC_009525.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase 282502 gabD1 5214190 gabD1 Mycobacterium tuberculosis H37Ra succinic semialdehyde dehydrogenase YP_001281521.1 280967 R 419947 CDS YP_001281522.1 148659999 5214191 complement(282528..283976) 1 NC_009525.1 transmembrane protein 283976 5214191 MRA_0243 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281522.1 282528 R 419947 CDS YP_001281523.1 148660000 5214192 complement(284011..288213) 1 NC_009525.1 transmembrane protein 288213 5214192 MRA_0244 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281523.1 284011 R 419947 CDS YP_001281524.1 148660001 5214193 complement(288260..288433) 1 NC_009525.1 small secreted protein 288433 5214193 MRA_0245 Mycobacterium tuberculosis H37Ra small secreted protein YP_001281524.1 288260 R 419947 CDS YP_001281525.1 148660002 5214194 288548..289714 1 NC_009525.1 lipoprotein LpqI 289714 lpqI 5214194 lpqI Mycobacterium tuberculosis H37Ra lipoprotein LpqI YP_001281525.1 288548 D 419947 CDS YP_001281526.1 148660003 5214931 289790..290404 1 NC_009525.1 TetR family transcriptional regulator 290404 5214931 MRA_0247 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001281526.1 289790 D 419947 CDS YP_001281527.1 148660004 5214932 290466..290699 1 NC_009525.1 hypothetical protein 290699 5214932 MRA_0248 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281527.1 290466 D 419947 CDS YP_001281528.1 148660005 5214933 290707..291144 1 NC_009525.1 hypothetical protein 291144 5214933 MRA_0249 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281528.1 290707 D 419947 CDS YP_001281529.1 148660006 5214934 complement(291174..292016) 1 NC_009525.1 hypothetical protein 292016 5214934 MRA_0250 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281529.1 291174 R 419947 CDS YP_001281530.1 148660007 5214935 complement(292027..293391) 1 NC_009525.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 293391 fabG 5214935 fabG Mycobacterium tuberculosis H37Ra 3-ketoacyl-ACP reductase YP_001281530.1 292027 R 419947 CDS YP_001281531.1 148660008 5214936 293533..294855 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 294855 fadA2 5214936 fadA2 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001281531.1 293533 D 419947 CDS YP_001281532.1 148660009 5211866 complement(295160..296995) 1 NC_009525.1 acyl-CoA dehydrogenase 296995 fadE5 5211866 fadE5 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001281532.1 295160 R 419947 CDS YP_001281533.1 148660010 5211867 297367..297855 1 NC_009525.1 oxidoreductase 297855 5211867 MRA_0254 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281533.1 297367 D 419947 CDS YP_001281534.1 148660011 5211868 298171..299481 1 NC_009525.1 integral membrane protein 299481 5211868 MRA_0255 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281534.1 298171 D 419947 CDS YP_001281535.1 148660012 5211869 complement(299478..300224) 1 NC_009525.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; fumarate reductase iron-sulfur subunit 300224 5211869 MRA_0256 Mycobacterium tuberculosis H37Ra fumarate reductase iron-sulfur subunit YP_001281535.1 299478 R 419947 CDS YP_001281536.1 148660013 5211870 complement(300225..302165) 1 NC_009525.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 302165 sdhA 5211870 sdhA Mycobacterium tuberculosis H37Ra succinate dehydrogenase flavoprotein subunit YP_001281536.1 300225 R 419947 CDS YP_001281537.1 148660014 5211871 complement(302196..303017) 1 NC_009525.1 succinate dehydrogenase 303017 5211871 MRA_0258 Mycobacterium tuberculosis H37Ra succinate dehydrogenase YP_001281537.1 302196 R 419947 CDS YP_001281538.1 148660015 5211872 complement(303097..303390) 1 NC_009525.1 hypothetical protein 303390 5211872 MRA_0259 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281538.1 303097 R 419947 CDS YP_001281539.1 148660016 5213637 complement(303535..304014) 1 NC_009525.1 heat shock protein Hsp 304014 hsp 5213637 hsp Mycobacterium tuberculosis H37Ra heat shock protein Hsp YP_001281539.1 303535 R 419947 CDS YP_001281540.1 148660017 5213638 304228..306789 1 NC_009525.1 NAD(P)H-dependent nitrite reductase large subunit 306789 nirB 5213638 nirB Mycobacterium tuberculosis H37Ra NAD(P)H-dependent nitrite reductase large subunit YP_001281540.1 304228 D 419947 CDS YP_001281541.1 148660018 5213639 306815..307171 1 NC_009525.1 nitrite reductase 307171 nirD 5213639 nirD Mycobacterium tuberculosis H37Ra nitrite reductase YP_001281541.1 306815 D 419947 CDS YP_001281542.1 148660019 5213640 complement(307187..307711) 1 NC_009525.1 cobinamide kinase/cobinamide phosphate guanylyltransferase 307711 cobU 5213640 cobU Mycobacterium tuberculosis H37Ra cobinamide kinase/cobinamide phosphate guanylyltransferase YP_001281542.1 307187 R 419947 CDS YP_001281543.1 148660020 5213641 complement(307736..309220) 1 NC_009525.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 309220 cobQ1 5213641 cobQ1 Mycobacterium tuberculosis H37Ra cobyric acid synthase YP_001281543.1 307736 R 419947 CDS YP_001281544.1 148660021 5213642 complement(309239..310801) 1 NC_009525.1 PPE family protein 310801 5213642 MRA_0265 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281544.1 309239 R 419947 CDS YP_001281545.1 148660022 5212687 311061..311435 1 NC_009525.1 hypothetical protein 311435 5212687 MRA_0265A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281545.1 311061 D 419947 CDS YP_001281546.1 148660023 5212688 complement(311656..312111) 1 NC_009525.1 hypothetical protein 312111 5212688 MRA_0266 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281546.1 311656 R 419947 CDS YP_001281547.1 148660024 5212689 complement(312136..312879) 1 NC_009525.1 hypothetical protein 312879 5212689 MRA_0267 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281547.1 312136 R 419947 CDS YP_001281548.1 148660025 5212690 complement(312876..314021) 1 NC_009525.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; bifunctional uroporphyrinogen-III synthetase/response regulator domain protein 314021 5212690 MRA_0268 Mycobacterium tuberculosis H37Ra bifunctional uroporphyrinogen-III synthetase/response regulator domain protein YP_001281548.1 312876 R 419947 CDS YP_001281549.1 148660026 5212691 complement(314121..315530) 1 NC_009525.1 integral membrane nitrite extrusion protein NarK3 315530 narK3 5212691 narK3 Mycobacterium tuberculosis H37Ra integral membrane nitrite extrusion protein NarK3 YP_001281549.1 314121 R 419947 CDS YP_001281550.1 148660027 5212692 complement(315671..316216) 1 NC_009525.1 aminoglycoside 2'-N-acetyltransferase 316216 aac 5212692 aac Mycobacterium tuberculosis H37Ra aminoglycoside 2'-N-acetyltransferase YP_001281550.1 315671 R 419947 CDS YP_001281551.1 148660028 5212693 complement(316226..317128) 1 NC_009525.1 hypothetical protein 317128 5212693 MRA_0271 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281551.1 316226 R 419947 CDS YP_001281552.1 148660029 5212087 complement(317145..317777) 1 NC_009525.1 hypothetical protein 317777 5212087 MRA_0272 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281552.1 317145 R 419947 CDS YP_001281553.1 148660030 5212088 complement(317873..318865) 1 NC_009525.1 iron ABC transporter substrate-binding protein 318865 5212088 MRA_0273 Mycobacterium tuberculosis H37Ra iron ABC transporter substrate-binding protein YP_001281553.1 317873 R 419947 CDS YP_001281554.1 148660031 5212089 complement(318887..322516) 1 NC_009525.1 5-oxoprolinase 322516 oplA 5212089 oplA Mycobacterium tuberculosis H37Ra 5-oxoprolinase YP_001281554.1 318887 R 419947 CDS YP_001281555.1 148660032 5212090 322693..324084 1 NC_009525.1 integral membrane nitrite extrusion protein NarU 324084 narU 5212090 narU Mycobacterium tuberculosis H37Ra integral membrane nitrite extrusion protein NarU YP_001281555.1 322693 D 419947 CDS YP_001281556.1 148660033 5212091 complement(324126..324635) 1 NC_009525.1 hypothetical protein 324635 5212091 MRA_0276 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281556.1 324126 R 419947 CDS YP_001281557.1 148660034 5212092 complement(324700..325893) 1 NC_009525.1 hypothetical protein 325893 5212092 MRA_0277 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281557.1 324700 R 419947 CDS YP_001281558.1 148660035 5212093 325929..327611 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 327611 fadD2 5212093 fadD2 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001281558.1 325929 D 419947 CDS YP_001281559.1 148660036 5212210 complement(327628..329823) 1 NC_009525.1 acyl-CoA dehydrogenase 329823 fadE6 5212210 fadE6 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001281559.1 327628 R 419947 CDS YP_001281560.1 148660037 5212211 complement(329937..331070) 1 NC_009525.1 hypothetical protein 331070 5212211 MRA_0280 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281560.1 329937 R 419947 CDS YP_001281561.1 148660038 5212212 complement(331067..331687) 1 NC_009525.1 transcriptional regulatory protein 331687 5212212 MRA_0281 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281561.1 331067 R 419947 CDS YP_001281562.1 148660039 5212213 331784..332365 1 NC_009525.1 hypothetical protein 332365 5212213 MRA_0282 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281562.1 331784 D 419947 CDS YP_001281563.1 148660040 5212214 complement(332295..333020) 1 NC_009525.1 MarR family transcriptional regulator 333020 5212214 MRA_0283 Mycobacterium tuberculosis H37Ra MarR family transcriptional regulator YP_001281563.1 332295 R 419947 CDS YP_001281564.1 148660041 5212215 333110..334030 1 NC_009525.1 hypothetical protein 334030 5212215 MRA_0284 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281564.1 333110 D 419947 CDS YP_001281565.1 148660042 5212216 complement(334070..334498) 1 NC_009525.1 hypothetical protein 334498 5212216 MRA_0285 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281565.1 334070 R 419947 CDS YP_001281566.1 148660043 5214355 complement(334522..334704) 1 NC_009525.1 hypothetical protein 334704 5214355 MRA_0286 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281566.1 334522 R 419947 CDS YP_001281567.1 148660044 5214356 complement(334799..337672) 1 NC_009525.1 PE-PGRS family protein 337672 5214356 MRA_0287 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001281567.1 334799 R 419947 CDS YP_001281568.1 148660045 5214357 complement(337922..340435) 1 NC_009525.1 PE-PGRS family protein 340435 5214357 MRA_0288 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001281568.1 337922 R 419947 CDS YP_001281569.1 148660046 5214358 340726..342336 1 NC_009525.1 PPE family protein 342336 5214358 MRA_0289 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281569.1 340726 D 419947 CDS YP_001281570.1 148660047 5214359 342360..343268 1 NC_009525.1 hypothetical protein 343268 5214359 MRA_0290 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281570.1 342360 D 419947 CDS YP_001281571.1 148660048 5214360 343492..345387 1 NC_009525.1 hypothetical protein 345387 5214360 MRA_0291 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281571.1 343492 D 419947 CDS YP_001281572.1 148660049 5212546 345384..347000 1 NC_009525.1 hypothetical protein 347000 5212546 MRA_0292 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281572.1 345384 D 419947 CDS YP_001281573.1 148660050 5212547 346997..350989 1 NC_009525.1 hypothetical protein 350989 5212547 MRA_0293 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281573.1 346997 D 419947 CDS YP_001281574.1 148660051 5212548 350986..351294 1 NC_009525.1 PE family protein 351294 5212548 MRA_0294 Mycobacterium tuberculosis H37Ra PE family protein YP_001281574.1 350986 D 419947 CDS YP_001281575.1 148660052 5212549 351345..352838 1 NC_009525.1 PPE family protein 352838 5212549 MRA_0295 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281575.1 351345 D 419947 CDS YP_001281576.1 148660053 5212550 352887..353180 1 NC_009525.1 PE family protein 353180 5212550 MRA_0296 Mycobacterium tuberculosis H37Ra PE family protein YP_001281576.1 352887 D 419947 CDS YP_001281577.1 148660054 5212551 353210..353500 1 NC_009525.1 antigen Esxh 353500 esxH 5212551 esxH Mycobacterium tuberculosis H37Ra antigen Esxh YP_001281577.1 353210 D 419947 CDS YP_001281578.1 148660055 5212552 353511..354398 1 NC_009525.1 hypothetical protein 354398 5212552 MRA_0298 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281578.1 353511 D 419947 CDS YP_001281579.1 148660056 5214764 354445..355863 1 NC_009525.1 transmembrane protein 355863 5214764 MRA_0299 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281579.1 354445 D 419947 CDS YP_001281580.1 148660057 5214765 355860..357245 1 NC_009525.1 membrane-anchored mycosin MycP3 357245 mycP3 5214765 mycP3 Mycobacterium tuberculosis H37Ra membrane-anchored mycosin MycP3 YP_001281580.1 355860 D 419947 CDS YP_001281581.1 148660058 5214766 357242..358237 1 NC_009525.1 transmembrane protein 358237 5214766 MRA_0301 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281581.1 357242 D 419947 CDS YP_001281582.1 148660059 5214767 complement(358224..359426) 1 NC_009525.1 hypothetical protein 359426 5214767 MRA_0302 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281582.1 358224 R 419947 CDS YP_001281583.1 148660060 5214768 359533..360318 1 NC_009525.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 360318 tam 5214768 tam Mycobacterium tuberculosis H37Ra trans-aconitate 2-methyltransferase YP_001281583.1 359533 D 419947 CDS YP_001281584.1 148660061 5214769 complement(360307..361110) 1 NC_009525.1 hypothetical protein 361110 5214769 MRA_0304 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281584.1 360307 R 419947 CDS YP_001281585.1 148660062 5214770 complement(361120..362517) 1 NC_009525.1 sulfatase 362517 5214770 MRA_0305 Mycobacterium tuberculosis H37Ra sulfatase YP_001281585.1 361120 R 419947 CDS YP_001281586.1 148660063 5214296 362696..364471 1 NC_009525.1 PE-PGRS family protein 364471 5214296 MRA_0306 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001281586.1 362696 D 419947 CDS YP_001281587.1 148660064 5214297 364614..364841 1 NC_009525.1 hypothetical protein 364841 5214297 MRA_0307 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281587.1 364614 D 419947 CDS YP_001281588.1 148660065 5214298 364838..365140 1 NC_009525.1 hypothetical protein 365140 5214298 MRA_0308 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281588.1 364838 D 419947 CDS YP_001281589.1 148660066 5214299 365188..365409 1 NC_009525.1 hypothetical protein 365409 5214299 MRA_0309 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281589.1 365188 D 419947 CDS YP_001281590.1 148660067 5214300 365406..365831 1 NC_009525.1 hypothetical protein 365831 5214300 MRA_0310 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281590.1 365406 D 419947 CDS YP_001281591.1 148660068 5214301 365967..366599 1 NC_009525.1 TetR/AcrR-family transcriptional regulator 366599 5214301 MRA_0311 Mycobacterium tuberculosis H37Ra TetR/AcrR-family transcriptional regulator YP_001281591.1 365967 D 419947 CDS YP_001281592.1 148660069 5211635 366596..367504 1 NC_009525.1 short-chain type dehydrogenase/reductase 367504 5211635 MRA_0312 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001281592.1 366596 D 419947 CDS YP_001281593.1 148660070 5211636 complement(367512..374633) 1 NC_009525.1 PPE family protein 374633 5211636 MRA_0313 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281593.1 367512 R 419947 CDS YP_001281594.1 148660071 5211637 complement(374182..377073) 1 NC_009525.1 PPE family protein 377073 5211637 MRA_0314 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281594.1 374182 R 419947 CDS YP_001281595.1 148660072 5211638 377276..377947 1 NC_009525.1 oxidoreductase 377947 5211638 MRA_0315 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281595.1 377276 D 419947 CDS YP_001281596.1 148660073 5211639 complement(377935..378417) 1 NC_009525.1 hypothetical protein 378417 5211639 MRA_0316 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281596.1 377935 R 419947 CDS YP_001281597.1 148660074 5211640 378475..379191 1 NC_009525.1 integral membrane protein 379191 5211640 MRA_0317 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281597.1 378475 D 419947 CDS YP_001281598.1 148660075 5211641 379293..379949 1 NC_009525.1 hypothetical protein 379949 5211641 MRA_0318 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281598.1 379293 D 419947 CDS YP_001281599.1 148660076 5212187 complement(380019..380510) 1 NC_009525.1 hypothetical protein 380510 5212187 MRA_0319 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281599.1 380019 R 419947 CDS YP_001281600.1 148660077 5212188 380534..381763 1 NC_009525.1 hypothetical protein 381763 5212188 MRA_0320 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281600.1 380534 D 419947 CDS YP_001281601.1 148660078 5212189 381918..383780 1 NC_009525.1 hypothetical protein 383780 5212189 MRA_0321 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281601.1 381918 D 419947 CDS YP_001281602.1 148660079 5212190 383852..384238 1 NC_009525.1 hypothetical protein 384238 5212190 MRA_0322 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281602.1 383852 D 419947 CDS YP_001281603.1 148660080 5212191 complement(384241..384903) 1 NC_009525.1 hypothetical protein 384903 5212191 MRA_0323 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281603.1 384241 R 419947 CDS YP_001281604.1 148660081 5212192 384964..385848 1 NC_009525.1 beta-glucanase 385848 5212192 MRA_0324 Mycobacterium tuberculosis H37Ra beta-glucanase YP_001281604.1 384964 D 419947 CDS YP_001281605.1 148660082 5211753 385897..386511 1 NC_009525.1 muconolactone isomerase 386511 5211753 MRA_0325 Mycobacterium tuberculosis H37Ra muconolactone isomerase YP_001281605.1 385897 D 419947 CDS YP_001281606.1 148660083 5211754 complement(386535..387305) 1 NC_009525.1 glycerophosphodiester phosphodiesterase; glycerophosphoryl diester phosphodiesterase; GlpQ2 387305 glpQ2 5211754 glpQ2 Mycobacterium tuberculosis H37Ra GlpQ2 YP_001281606.1 386535 R 419947 CDS YP_001281607.1 148660084 5211756 complement(387667..388461) 1 NC_009525.1 hypothetical protein 388461 5211756 MRA_0327 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281607.1 387667 R 419947 CDS YP_001281608.1 148660085 5211757 388510..389178 1 NC_009525.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 389178 pcp 5211757 pcp Mycobacterium tuberculosis H37Ra pyrrolidone-carboxylate peptidase YP_001281608.1 388510 D 419947 CDS YP_001281609.1 148660086 5211758 389250..389912 1 NC_009525.1 hypothetical protein 389912 5211758 MRA_0329 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281609.1 389250 D 419947 CDS YP_001281610.1 148660087 5214388 389944..390516 1 NC_009525.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 390516 dcd 5214388 dcd Mycobacterium tuberculosis H37Ra deoxycytidine triphosphate deaminase YP_001281610.1 389944 D 419947 CDS YP_001281611.1 148660088 5214389 390622..391953 1 NC_009525.1 UDP-glucose 6-dehydrogenase 391953 udgA 5214389 udgA Mycobacterium tuberculosis H37Ra UDP-glucose 6-dehydrogenase YP_001281611.1 390622 D 419947 CDS YP_001281612.1 148660089 5214390 complement(391942..392613) 1 NC_009525.1 hypothetical protein 392613 5214390 MRA_0332 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281612.1 391942 R 419947 CDS YP_001281613.1 148660090 5214391 392714..393394 1 NC_009525.1 transcription regulator ArsR 393394 5214391 MRA_0333 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001281613.1 392714 D 419947 CDS YP_001281614.1 148660091 5214392 393401..393625 1 NC_009525.1 hypothetical protein 393625 5214392 MRA_0334 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281614.1 393401 D 419947 CDS YP_001281615.1 148660092 5214393 393635..394090 1 NC_009525.1 hypothetical protein 394090 5214393 MRA_0335 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281615.1 393635 D 419947 CDS YP_001281616.1 148660093 5211717 complement(394058..395407) 1 NC_009525.1 cytochrome p450 135A1 Cyp135A1 395407 cyp135A1 5211717 cyp135A1 Mycobacterium tuberculosis H37Ra cytochrome p450 135A1 Cyp135A1 YP_001281616.1 394058 R 419947 CDS YP_001281617.1 148660094 5211718 395473..396075 1 NC_009525.1 TetR/AcrR-family transcriptional regulator 396075 5211718 MRA_0337 Mycobacterium tuberculosis H37Ra TetR/AcrR-family transcriptional regulator YP_001281617.1 395473 D 419947 CDS YP_001281618.1 148660095 5211719 complement(396056..396682) 1 NC_009525.1 hypothetical protein 396682 5211719 MRA_0338 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281618.1 396056 R 419947 CDS YP_001281619.1 148660096 5211720 complement(396709..397449) 1 NC_009525.1 hypothetical protein 397449 5211720 MRA_0339 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281619.1 396709 R 419947 CDS YP_001281620.1 148660097 5211721 397563..398729 1 NC_009525.1 phage tail component protein 398729 5211721 MRA_0340 Mycobacterium tuberculosis H37Ra phage tail component protein YP_001281620.1 397563 D 419947 CDS YP_001281621.1 148660098 5211722 398804..399589 1 NC_009525.1 hypothetical protein 399589 5211722 MRA_0341 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281621.1 398804 D 419947 CDS YP_001281622.1 148660099 5211723 399616..399990 1 NC_009525.1 hypothetical protein 399990 5211723 MRA_0342 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281622.1 399616 D 419947 CDS YP_001281623.1 148660100 5212878 400020..400886 1 NC_009525.1 glucose-1-phosphate thymidylyltransferase 400886 rmlA 5212878 rmlA Mycobacterium tuberculosis H37Ra glucose-1-phosphate thymidylyltransferase YP_001281623.1 400020 D 419947 CDS YP_001281624.1 148660101 5212879 complement(400897..401412) 1 NC_009525.1 PE family protein 401412 5212879 MRA_0344 Mycobacterium tuberculosis H37Ra PE family protein YP_001281624.1 400897 R 419947 CDS YP_001281625.1 148660102 5212880 401554..403065 1 NC_009525.1 hypothetical protein 403065 5212880 MRA_0345 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281625.1 401554 D 419947 CDS YP_001281626.1 148660103 5212881 complement(403235..404524) 1 NC_009525.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 404524 aspC 5212881 aspC Mycobacterium tuberculosis H37Ra aminotransferase YP_001281626.1 403235 R 419947 CDS YP_001281627.1 148660104 5212882 complement(404555..407203) 1 NC_009525.1 iron-sulfur-binding reductase 407203 5212882 MRA_0347 Mycobacterium tuberculosis H37Ra iron-sulfur-binding reductase YP_001281627.1 404555 R 419947 CDS YP_001281628.1 148660105 5212883 complement(407312..409810) 1 NC_009525.1 LuxR family transcriptional regulator 409810 5212883 MRA_0348 Mycobacterium tuberculosis H37Ra LuxR family transcriptional regulator YP_001281628.1 407312 R 419947 CDS YP_001281629.1 148660106 5212884 409996..410535 1 NC_009525.1 hypothetical protein 410535 5212884 MRA_0349 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281629.1 409996 D 419947 CDS YP_001281630.1 148660107 5211710 410724..412163 1 NC_009525.1 isoniazid inductible gene protein IniB 412163 iniB 5211710 iniB Mycobacterium tuberculosis H37Ra isoniazid inductible gene protein IniB YP_001281630.1 410724 D 419947 CDS YP_001281631.1 148660108 5211711 412200..414122 1 NC_009525.1 isoniazid inductible gene protein IniA 414122 iniA 5211711 iniA Mycobacterium tuberculosis H37Ra isoniazid inductible gene protein IniA YP_001281631.1 412200 D 419947 CDS YP_001281632.1 148660109 5211712 414119..415600 1 NC_009525.1 isoniazid inductible gene protein IniC 415600 iniC 5211712 iniC Mycobacterium tuberculosis H37Ra isoniazid inductible gene protein IniC YP_001281632.1 414119 D 419947 CDS YP_001281633.1 148660110 5211713 complement(415743..416303) 1 NC_009525.1 lipoprotein LpqJ 416303 lpqJ 5211713 lpqJ Mycobacterium tuberculosis H37Ra lipoprotein LpqJ YP_001281633.1 415743 R 419947 CDS YP_001281634.1 148660111 5211714 416412..416822 1 NC_009525.1 hypothetical protein 416822 5211714 MRA_0354 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281634.1 416412 D 419947 CDS YP_001281635.1 148660112 5211715 complement(416864..418327) 1 NC_009525.1 L-asparagine permease 418327 ansP2 5211715 ansP2 Mycobacterium tuberculosis H37Ra L-asparagine permease YP_001281635.1 416864 R 419947 CDS YP_001281636.1 148660113 5211716 418666..419652 1 NC_009525.1 hypothetical protein 419652 5211716 MRA_0356 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281636.1 418666 D 419947 CDS YP_001281637.1 148660114 5211724 419655..420308 1 NC_009525.1 transcriptional regulatory protein 420308 5211724 MRA_0357 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281637.1 419655 D 419947 CDS YP_001281638.1 148660115 5211725 420311..420970 1 NC_009525.1 hypothetical protein 420970 5211725 MRA_0358 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281638.1 420311 D 419947 CDS YP_001281639.1 148660116 5211726 421197..423074 1 NC_009525.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 423074 dnaK 5211726 dnaK Mycobacterium tuberculosis H37Ra molecular chaperone DnaK YP_001281639.1 421197 D 419947 CDS YP_001281640.1 148660117 5211727 423071..423778 1 NC_009525.1 Hsp-70 cofactor; with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 423778 grpE 5211727 grpE Mycobacterium tuberculosis H37Ra heat shock protein GrpE YP_001281640.1 423071 D 419947 CDS YP_001281641.1 148660118 5211728 423814..425001 1 NC_009525.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 425001 dnaJ1 5211728 dnaJ1 Mycobacterium tuberculosis H37Ra molecular chaperone DnaJ YP_001281641.1 423814 D 419947 CDS YP_001281642.1 148660119 5211729 425001..425381 1 NC_009525.1 heat shock protein transcriptional repressor HspR 425381 hspR 5211729 hspR Mycobacterium tuberculosis H37Ra heat shock protein transcriptional repressor HspR YP_001281642.1 425001 D 419947 CDS YP_001281643.1 148660120 5212080 complement(425506..426063) 1 NC_009525.1 PPE family protein 426063 5212080 MRA_0363 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281643.1 425506 R 419947 CDS YP_001281644.1 148660121 5212081 complement(426140..436042) 1 NC_009525.1 PPE family protein 436042 5212081 MRA_0364 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281644.1 426140 R 419947 CDS YP_001281645.1 148660122 5212082 complement(436193..436837) 1 NC_009525.1 hypothetical protein 436837 5212082 MRA_0365 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281645.1 436193 R 419947 CDS YP_001281646.1 148660123 5212083 complement(436834..438132) 1 NC_009525.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 438132 purA 5212083 purA Mycobacterium tuberculosis H37Ra adenylosuccinate synthetase YP_001281646.1 436834 R 419947 CDS YP_001281647.1 148660124 5212084 438223..438870 1 NC_009525.1 hypothetical protein 438870 5212084 MRA_0367 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281647.1 438223 D 419947 CDS YP_001281648.1 148660125 5212085 438881..439660 1 NC_009525.1 integral membrane protein 439660 5212085 MRA_0368 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281648.1 438881 D 419947 CDS YP_001281649.1 148660126 5212086 complement(439665..440102) 1 NC_009525.1 hypothetical protein 440102 5212086 MRA_0369 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281649.1 439665 R 419947 CDS YP_001281650.1 148660127 5212985 440185..441012 1 NC_009525.1 hypothetical protein 441012 5212985 MRA_0370 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281650.1 440185 D 419947 CDS YP_001281651.1 148660128 5212986 441234..442616 1 NC_009525.1 Mg2+ transport transmembrane protein MgtE 442616 mgtE 5212986 mgtE Mycobacterium tuberculosis H37Ra Mg2+ transport transmembrane protein MgtE YP_001281651.1 441234 D 419947 CDS YP_001281652.1 148660129 5212987 complement(442628..443662) 1 NC_009525.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 443662 fba 5212987 fba Mycobacterium tuberculosis H37Ra fructose-bisphosphate aldolase YP_001281652.1 442628 R 419947 CDS YP_001281653.1 148660130 5212988 443758..444441 1 NC_009525.1 transmembrane protein 444441 5212988 MRA_0373 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281653.1 443758 D 419947 CDS YP_001281654.1 148660131 5212989 complement(444430..445560) 1 NC_009525.1 hypothetical protein 445560 5212989 MRA_0374 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281654.1 444430 R 419947 CDS YP_001281655.1 148660132 5212990 complement(445585..446178) 1 NC_009525.1 hypothetical protein 446178 5212990 MRA_0375 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281655.1 445585 R 419947 CDS YP_001281656.1 148660133 5212991 446189..446617 1 NC_009525.1 hypothetical protein 446617 5212991 MRA_0376 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281656.1 446189 D 419947 CDS YP_001281657.1 148660134 5214916 complement(446677..447888) 1 NC_009525.1 hypothetical protein 447888 5214916 MRA_0377 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281657.1 446677 R 419947 CDS YP_001281658.1 148660135 5214917 complement(447894..448409) 1 NC_009525.1 membrane oxidoreductase 448409 5214917 MRA_0378 Mycobacterium tuberculosis H37Ra membrane oxidoreductase YP_001281658.1 447894 R 419947 CDS YP_001281659.1 148660136 5214918 complement(448510..449406) 1 NC_009525.1 oxidoreductase 449406 5214918 MRA_0379 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281659.1 448510 R 419947 CDS YP_001281660.1 148660137 5214919 complement(449403..449996) 1 NC_009525.1 hypothetical protein 449996 5214919 MRA_0380 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281660.1 449403 R 419947 CDS YP_001281661.1 148660138 5214920 complement(449993..450748) 1 NC_009525.1 hypothetical protein 450748 5214920 MRA_0381 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281661.1 449993 R 419947 CDS YP_001281662.1 148660139 5214921 complement(450767..453166) 1 NC_009525.1 carbon monoxide dehydrogenase large subunit 453166 5214921 MRA_0382 Mycobacterium tuberculosis H37Ra carbon monoxide dehydrogenase large subunit YP_001281662.1 450767 R 419947 CDS YP_001281663.1 148660140 5215075 complement(453163..453642) 1 NC_009525.1 carbon monoxide dehydrogenase small subunit 453642 5215075 MRA_0383 Mycobacterium tuberculosis H37Ra carbon monoxide dehydrogenase small subunit YP_001281663.1 453163 R 419947 CDS YP_001281664.1 148660141 5215076 complement(453657..454517) 1 NC_009525.1 carbon monoxide dehydrogenase medium subunit 454517 5215076 MRA_0384 Mycobacterium tuberculosis H37Ra carbon monoxide dehydrogenase medium subunit YP_001281664.1 453657 R 419947 CDS YP_001281665.1 148660142 5215077 complement(454593..455735) 1 NC_009525.1 hypothetical protein 455735 5215077 MRA_0385 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281665.1 454593 R 419947 CDS YP_001281666.1 148660143 5215078 455784..456749 1 NC_009525.1 LysR family transcriptional regulator 456749 5215078 MRA_0386 Mycobacterium tuberculosis H37Ra LysR family transcriptional regulator YP_001281666.1 455784 D 419947 CDS YP_001281667.1 148660144 5215079 457000..457221 1 NC_009525.1 hypothetical protein 457221 5215079 MRA_0386A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281667.1 457000 D 419947 CDS YP_001281668.1 148660145 5215080 457340..457555 1 NC_009525.1 protein transport protein SecE2 457555 secE2 5215080 secE2 Mycobacterium tuberculosis H37Ra protein transport protein SecE2 YP_001281668.1 457340 D 419947 CDS YP_001281669.1 148660146 5215081 complement(457631..458293) 1 NC_009525.1 RNA methyltransferase 458293 5215081 MRA_0388 Mycobacterium tuberculosis H37Ra RNA methyltransferase YP_001281669.1 457631 R 419947 CDS YP_001281670.1 148660147 5215544 complement(458278..459186) 1 NC_009525.1 hypothetical protein 459186 5215544 MRA_0389 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281670.1 458278 R 419947 CDS YP_001281671.1 148660148 5215545 complement(459204..459743) 1 NC_009525.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 459743 pyrE 5215545 pyrE Mycobacterium tuberculosis H37Ra orotate phosphoribosyltransferase YP_001281671.1 459204 R 419947 CDS YP_001281672.1 148660149 5215546 complement(459824..460678) 1 NC_009525.1 hypothetical protein 460678 5215546 MRA_0391 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281672.1 459824 R 419947 CDS YP_001281673.1 148660150 5215547 complement(460764..463310) 1 NC_009525.1 ATP-dependent Clp protease ATP-binding subunit ClpB 463310 clpB 5215547 clpB Mycobacterium tuberculosis H37Ra ATP-dependent Clp protease ATP-binding subunit ClpB YP_001281673.1 460764 R 419947 CDS YP_001281674.1 148660151 5215548 463443..464615 1 NC_009525.1 hypothetical protein 464615 5215548 MRA_0393 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281674.1 463443 D 419947 CDS YP_001281675.1 148660152 5215549 464719..467976 1 NC_009525.1 LuxR family transcriptional regulator 467976 5215549 MRA_0394 Mycobacterium tuberculosis H37Ra LuxR family transcriptional regulator YP_001281675.1 464719 D 419947 CDS YP_001281676.1 148660153 5215550 complement(467980..469311) 1 NC_009525.1 PPE family protein 469311 5215550 MRA_0395 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281676.1 467980 R 419947 CDS YP_001281677.1 148660154 5213888 469645..470904 1 NC_009525.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 470904 purT 5213888 purT Mycobacterium tuberculosis H37Ra phosphoribosylglycinamide formyltransferase 2 YP_001281677.1 469645 D 419947 CDS YP_001281678.1 148660155 5213889 470901..471323 1 NC_009525.1 hypothetical protein 471323 5213889 MRA_0397 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281678.1 470901 D 419947 CDS YP_001281679.1 148660156 5213890 471320..472540 1 NC_009525.1 O-succinylhomoserine sulfhydrylase 472540 metZ 5213890 metZ Mycobacterium tuberculosis H37Ra O-succinylhomoserine sulfhydrylase YP_001281679.1 471320 D 419947 CDS YP_001281680.1 148660157 5213891 complement(472537..473949) 1 NC_009525.1 membrane NADH dehydrogenase NdhA 473949 ndhA 5213891 ndhA Mycobacterium tuberculosis H37Ra membrane NADH dehydrogenase NdhA YP_001281680.1 472537 R 419947 CDS YP_001281681.1 148660158 5213892 474091..475416 1 NC_009525.1 hypothetical protein 475416 5213892 MRA_0400 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281681.1 474091 D 419947 CDS YP_001281682.1 148660159 5213893 complement(475432..476151) 1 NC_009525.1 secreted protein 476151 5213893 MRA_0401 Mycobacterium tuberculosis H37Ra secreted protein YP_001281682.1 475432 R 419947 CDS YP_001281683.1 148660160 5213894 476250..476654 1 NC_009525.1 hypothetical protein 476654 5213894 MRA_0401A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281683.1 476250 D 419947 CDS YP_001281684.1 148660161 5212491 476660..477052 1 NC_009525.1 hypothetical protein 477052 5212491 MRA_0402 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281684.1 476660 D 419947 CDS YP_001281685.1 148660162 5212492 complement(477093..477563) 1 NC_009525.1 hypothetical protein 477563 5212492 MRA_0403 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281685.1 477093 R 419947 CDS YP_001281686.1 148660163 5212493 complement(477989..478630) 1 NC_009525.1 secreted protein 478630 5212493 MRA_0404 Mycobacterium tuberculosis H37Ra secreted protein YP_001281686.1 477989 R 419947 CDS YP_001281687.1 148660164 5212494 complement(478637..479866) 1 NC_009525.1 lipoprotein LpqK 479866 lpqK 5212494 lpqK Mycobacterium tuberculosis H37Ra lipoprotein LpqK YP_001281687.1 478637 R 419947 CDS YP_001281688.1 148660165 5212495 complement(479876..481063) 1 NC_009525.1 glutaryl-CoA dehydrogenase 481063 fadE7 5212495 fadE7 Mycobacterium tuberculosis H37Ra glutaryl-CoA dehydrogenase YP_001281688.1 479876 R 419947 CDS YP_001281689.1 148660166 5212496 481099..481470 1 NC_009525.1 transmembrane protein 481470 5212496 MRA_0407 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281689.1 481099 D 419947 CDS YP_001281690.1 148660167 5212992 complement(481665..484541) 1 NC_009525.1 transmembrane transport protein MmpL1 484541 mmpL1 5212992 mmpL1 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL1 YP_001281690.1 481665 R 419947 CDS YP_001281691.1 148660168 5212993 complement(484538..484966) 1 NC_009525.1 membrane protein MmpS1 484966 mmpS1 5212993 mmpS1 Mycobacterium tuberculosis H37Ra membrane protein MmpS1 YP_001281691.1 484538 R 419947 CDS YP_001281692.1 148660169 5212994 485287..487044 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 487044 fadD30 5212994 fadD30 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001281692.1 485287 D 419947 CDS YP_001281693.1 148660170 5212995 487041..491249 1 NC_009525.1 membrane bound polyketide synthase Pks6 491249 pks6 5212995 pks6 Mycobacterium tuberculosis H37Ra membrane bound polyketide synthase Pks6 YP_001281693.1 487041 D 419947 CDS YP_001281694.1 148660171 5212996 complement(491197..492015) 1 NC_009525.1 beta lactamase like protein 492015 5212996 MRA_0412 Mycobacterium tuberculosis H37Ra beta lactamase like protein YP_001281694.1 491197 R 419947 CDS YP_001281695.1 148660172 5212997 492093..493103 1 NC_009525.1 f420-dependent glucose-6-phosphate dehydrogenase Fgd1 493103 fgd1 5212997 fgd1 Mycobacterium tuberculosis H37Ra f420-dependent glucose-6-phosphate dehydrogenase Fgd1 YP_001281695.1 492093 D 419947 CDS YP_001281696.1 148660173 5212998 493096..495168 1 NC_009525.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 495168 pta 5212998 pta Mycobacterium tuberculosis H37Ra phosphate acetyltransferase YP_001281696.1 493096 D 419947 CDS YP_001281697.1 148660174 5214249 495161..496318 1 NC_009525.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 496318 ackA 5214249 ackA Mycobacterium tuberculosis H37Ra acetate kinase YP_001281697.1 495161 D 419947 CDS YP_001281698.1 148660175 5214250 complement(496372..498624) 1 NC_009525.1 serine/threonine protein kinase 498624 pknG 5214250 pknG Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001281698.1 496372 R 419947 CDS YP_001281699.1 148660176 5214251 complement(498624..499610) 1 NC_009525.1 amino acid ABC transporter substrate-binding protein 499610 glnH 5214251 glnH Mycobacterium tuberculosis H37Ra amino acid ABC transporter substrate-binding protein YP_001281699.1 498624 R 419947 CDS YP_001281700.1 148660177 5214252 complement(499610..500929) 1 NC_009525.1 hypothetical protein 500929 5214252 MRA_0418 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281700.1 499610 R 419947 CDS YP_001281701.1 148660178 5214253 501023..501676 1 NC_009525.1 mutator protein MutT3 501676 mutT3 5214253 mutT3 Mycobacterium tuberculosis H37Ra mutator protein MutT3 YP_001281701.1 501023 D 419947 CDS YP_001281702.1 148660179 5214254 complement(501660..502328) 1 NC_009525.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 502328 thiE 5214254 thiE Mycobacterium tuberculosis H37Ra thiamine-phosphate pyrophosphorylase YP_001281702.1 501660 R 419947 CDS YP_001281703.1 148660180 5214255 502458..503480 1 NC_009525.1 amino acid oxidase flavoprotein ThiO 503480 thiO 5214255 thiO Mycobacterium tuberculosis H37Ra amino acid oxidase flavoprotein ThiO YP_001281703.1 502458 D 419947 CDS YP_001281704.1 148660181 5215113 503477..503683 1 NC_009525.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 503683 thiS 5215113 thiS Mycobacterium tuberculosis H37Ra sulfur carrier protein ThiS YP_001281704.1 503477 D 419947 CDS YP_001281705.1 148660182 5215114 503676..504434 1 NC_009525.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 504434 thiG 5215114 thiG Mycobacterium tuberculosis H37Ra thiazole synthase YP_001281705.1 503676 D 419947 CDS YP_001281706.1 148660183 5215115 504806..506308 1 NC_009525.1 lipoprotein aminopeptidase LpqL 506308 lpqL 5215115 lpqL Mycobacterium tuberculosis H37Ra lipoprotein aminopeptidase LpqL YP_001281706.1 504806 D 419947 CDS YP_001281707.1 148660184 5215116 506396..507892 1 NC_009525.1 lipoprotein peptidase LpqM 507892 lpqM 5215116 lpqM Mycobacterium tuberculosis H37Ra lipoprotein peptidase LpqM YP_001281707.1 506396 D 419947 CDS YP_001281708.1 148660185 5215117 complement(507871..508281) 1 NC_009525.1 transmembrane protein 508281 5215117 MRA_0426 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281708.1 507871 R 419947 CDS YP_001281709.1 148660186 5215118 complement(508442..509071) 1 NC_009525.1 hypothetical protein 509071 5215118 MRA_0427 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281709.1 508442 R 419947 CDS YP_001281710.1 148660187 5215681 complement(509068..509865) 1 NC_009525.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 509865 thiD 5215681 thiD Mycobacterium tuberculosis H37Ra phosphomethylpyrimidine kinase YP_001281710.1 509068 R 419947 CDS YP_001281711.1 148660188 5215682 complement(509892..511535) 1 NC_009525.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 511535 thiC 5215682 thiC Mycobacterium tuberculosis H37Ra thiamine biosynthesis protein ThiC YP_001281711.1 509892 R 419947 CDS YP_001281712.1 148660189 5215683 complement(511687..511962) 1 NC_009525.1 hypothetical protein 511962 5215683 MRA_0429A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281712.1 511687 R 419947 CDS YP_001281713.1 148660190 5215684 complement(512012..516631) 1 NC_009525.1 metal cation transporting P-type ATPase CtpH 516631 ctpH 5215684 ctpH Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpH YP_001281713.1 512012 R 419947 CDS YP_001281714.1 148660191 5215685 complement(516683..517126) 1 NC_009525.1 hypothetical protein 517126 5215685 MRA_0431 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281714.1 516683 R 419947 CDS YP_001281715.1 148660192 5215686 complement(517327..518202) 1 NC_009525.1 exodeoxyribonuclease III 518202 xthA 5215686 xthA Mycobacterium tuberculosis H37Ra exodeoxyribonuclease III YP_001281715.1 517327 R 419947 CDS YP_001281716.1 148660193 5215687 complement(518205..519113) 1 NC_009525.1 hypothetical protein 519113 5215687 MRA_0433 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281716.1 518205 R 419947 CDS YP_001281717.1 148660194 5213565 complement(519113..519706) 1 NC_009525.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 519706 def 5213565 def Mycobacterium tuberculosis H37Ra peptide deformylase YP_001281717.1 519113 R 419947 CDS YP_001281718.1 148660195 5213566 520043..520351 1 NC_009525.1 hypothetical protein 520351 5213566 MRA_0435 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281718.1 520043 D 419947 CDS YP_001281719.1 148660196 5213567 520383..520877 1 NC_009525.1 tuberculin related peptide 520877 5213567 MRA_0436 Mycobacterium tuberculosis H37Ra tuberculin related peptide YP_001281719.1 520383 D 419947 CDS YP_001281720.1 148660197 5213568 520910..521632 1 NC_009525.1 superoxide dismutase 521632 sodC 5213568 sodC Mycobacterium tuberculosis H37Ra superoxide dismutase YP_001281720.1 520910 D 419947 CDS YP_001281721.1 148660198 5213569 521634..522764 1 NC_009525.1 ATP-dependent carboxylate-amine ligase; carboxylate-amine ligase 522764 5213569 MRA_0438 Mycobacterium tuberculosis H37Ra carboxylate-amine ligase YP_001281721.1 521634 D 419947 CDS YP_001281722.1 148660199 5213570 522824..523477 1 NC_009525.1 hypothetical protein 523477 5213570 MRA_0439 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281722.1 522824 D 419947 CDS YP_001281723.1 148660200 5213571 complement(523657..525843) 1 NC_009525.1 cell division control protein 525843 5213571 MRA_0440 Mycobacterium tuberculosis H37Ra cell division control protein YP_001281723.1 523657 R 419947 CDS YP_001281724.1 148660201 5214289 complement(525840..526700) 1 NC_009525.1 CDP-diacylglycerol--serine O-phosphatidyltransferase 526700 pssA 5214289 pssA Mycobacterium tuberculosis H37Ra CDP-diacylglycerol--serine O-phosphatidyltransferase YP_001281724.1 525840 R 419947 CDS YP_001281725.1 148660202 5214290 complement(526697..527392) 1 NC_009525.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 527392 psd 5214290 psd Mycobacterium tuberculosis H37Ra phosphatidylserine decarboxylase YP_001281725.1 526697 R 419947 CDS YP_001281726.1 148660203 5214291 complement(527453..528670) 1 NC_009525.1 molybdopterin biosynthesis protein MoeA2 528670 moeA2 5214291 moeA2 Mycobacterium tuberculosis H37Ra molybdopterin biosynthesis protein MoeA2 YP_001281726.1 527453 R 419947 CDS YP_001281727.1 148660204 5214292 complement(528689..529624) 1 NC_009525.1 short chain dehydrogenase 529624 5214292 MRA_0444 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001281727.1 528689 R 419947 CDS YP_001281728.1 148660205 5214293 529918..531540 1 NC_009525.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 531540 groEL 5214293 groEL Mycobacterium tuberculosis H37Ra molecular chaperone GroEL YP_001281728.1 529918 D 419947 CDS YP_001281729.1 148660206 5214294 complement(531606..532034) 1 NC_009525.1 hypothetical protein 532034 5214294 MRA_0446 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281729.1 531606 R 419947 CDS YP_001281730.1 148660207 5214295 complement(532061..533524) 1 NC_009525.1 PPE family protein 533524 5214295 MRA_0447 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281730.1 532061 R 419947 CDS YP_001281731.1 148660208 5215055 533706..534221 1 NC_009525.1 hypothetical protein 534221 5215055 MRA_0448 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281731.1 533706 D 419947 CDS YP_001281732.1 148660209 5215056 complement(534401..535099) 1 NC_009525.1 hypothetical protein 535099 5215056 MRA_0449 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281732.1 534401 R 419947 CDS YP_001281733.1 148660210 5215057 complement(535143..535706) 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; RNA polymerase sigma factor SigK 535706 sigK 5215057 sigK Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigK YP_001281733.1 535143 R 419947 CDS YP_001281734.1 148660211 5215058 complement(535755..536525) 1 NC_009525.1 hypothetical protein 536525 5215058 MRA_0451 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281734.1 535755 R 419947 CDS YP_001281735.1 148660212 5215059 complement(536534..537817) 1 NC_009525.1 cyclopropane-fatty-acyl-phospholipid synthase UfaA1 537817 ufaA1 5215059 ufaA1 Mycobacterium tuberculosis H37Ra cyclopropane-fatty-acyl-phospholipid synthase UfaA1 YP_001281735.1 536534 R 419947 CDS YP_001281736.1 148660213 5215060 complement(537814..538479) 1 NC_009525.1 hypothetical protein 538479 5215060 MRA_0453 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281736.1 537814 R 419947 CDS YP_001281737.1 148660214 5215201 complement(538539..539858) 1 NC_009525.1 hypothetical protein 539858 5215201 MRA_0454 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281737.1 538539 R 419947 CDS YP_001281738.1 148660215 5215202 complement(539898..542801) 1 NC_009525.1 transmembrane transport protein MmpL4 542801 mmpL4 5215202 mmpL4 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL4 YP_001281738.1 539898 R 419947 CDS YP_001281739.1 148660216 5215203 complement(542798..543220) 1 NC_009525.1 membrane protein MmpS4 543220 mmpS4 5215203 mmpS4 Mycobacterium tuberculosis H37Ra membrane protein MmpS4 YP_001281739.1 542798 R 419947 CDS YP_001281740.1 148660217 5215204 543452..544162 1 NC_009525.1 transcriptional regulatory protein 544162 5215204 MRA_0457 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281740.1 543452 D 419947 CDS YP_001281741.1 148660218 5215205 544505..546040 1 NC_009525.1 PPE family protein 546040 5215205 MRA_0458 Mycobacterium tuberculosis H37Ra PPE family protein YP_001281741.1 544505 D 419947 CDS YP_001281742.1 148660219 5215206 complement(546046..546600) 1 NC_009525.1 hypothetical protein 546600 5215206 MRA_0459 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281742.1 546046 R 419947 CDS YP_001281743.1 148660220 5215207 complement(546685..547131) 1 NC_009525.1 hypothetical protein 547131 5215207 MRA_0460 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281743.1 546685 R 419947 CDS YP_001281744.1 148660221 5215537 complement(547199..548113) 1 NC_009525.1 catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 548113 echA2 5215537 echA2 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001281744.1 547199 R 419947 CDS YP_001281745.1 148660222 5215538 complement(548386..548667) 1 NC_009525.1 hypothetical protein 548667 5215538 MRA_0462 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281745.1 548386 R 419947 CDS YP_001281746.1 148660223 5215539 complement(548896..550917) 1 NC_009525.1 prolyl oligopeptidase 550917 5215539 MRA_0463 Mycobacterium tuberculosis H37Ra prolyl oligopeptidase YP_001281746.1 548896 R 419947 CDS YP_001281747.1 148660224 5215540 550985..552508 1 NC_009525.1 aldehyde dehydrogenase 552508 5215540 MRA_0464 Mycobacterium tuberculosis H37Ra aldehyde dehydrogenase YP_001281747.1 550985 D 419947 CDS YP_001281748.1 148660225 5215541 552508..552999 1 NC_009525.1 hypothetical protein 552999 5215541 MRA_0465 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281748.1 552508 D 419947 CDS YP_001281749.1 148660226 5215542 553059..553298 1 NC_009525.1 hypothetical protein 553298 5215542 MRA_0466 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281749.1 553059 D 419947 CDS YP_001281750.1 148660227 5215543 553336..553860 1 NC_009525.1 hypothetical protein 553860 5215543 MRA_0467 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281750.1 553336 D 419947 CDS YP_001281751.1 148660228 5215573 553924..555318 1 NC_009525.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; dihydrolipoamide dehydrogenase 555318 lpd 5215573 lpd Mycobacterium tuberculosis H37Ra dihydrolipoamide dehydrogenase YP_001281751.1 553924 D 419947 CDS YP_001281752.1 148660229 5215574 555326..555619 1 NC_009525.1 hypothetical protein 555619 5215574 MRA_0469 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281752.1 555326 D 419947 CDS YP_001281753.1 148660230 5215575 complement(555623..556195) 1 NC_009525.1 hypothetical protein 556195 5215575 MRA_0470 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281753.1 555623 R 419947 CDS YP_001281754.1 148660231 5215576 complement(556192..557616) 1 NC_009525.1 transcriptional regulatory protein 557616 5215576 MRA_0471 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281754.1 556192 R 419947 CDS YP_001281755.1 148660232 5215577 557768..558562 1 NC_009525.1 hypothetical protein 558562 5215577 MRA_0472 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281755.1 557768 D 419947 CDS YP_001281756.1 148660233 5215578 558837..560123 1 NC_009525.1 isocitrate lyase Icl 560123 icl 5215578 icl Mycobacterium tuberculosis H37Ra isocitrate lyase Icl YP_001281756.1 558837 D 419947 CDS YP_001281757.1 148660234 5215579 560205..561065 1 NC_009525.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 561065 fadB2 5215579 fadB2 Mycobacterium tuberculosis H37Ra 3-hydroxybutyryl-CoA dehydrogenase YP_001281757.1 560205 D 419947 CDS YP_001281758.1 148660235 5215612 561198..562058 1 NC_009525.1 mycolic acid synthase UmaA 562058 umaA 5215612 umaA Mycobacterium tuberculosis H37Ra mycolic acid synthase UmaA YP_001281758.1 561198 D 419947 CDS YP_001281759.1 148660236 5215613 complement(562158..563021) 1 NC_009525.1 mycolic acid synthase PcaA 563021 pcaA 5215613 pcaA Mycobacterium tuberculosis H37Ra mycolic acid synthase PcaA YP_001281759.1 562158 R 419947 CDS YP_001281760.1 148660237 5215614 complement(563164..563604) 1 NC_009525.1 hypothetical protein 563604 5215614 MRA_0477 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281760.1 563164 R 419947 CDS YP_001281761.1 148660238 5215615 complement(563535..564023) 1 NC_009525.1 hypothetical protein 564023 5215615 MRA_0478 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281761.1 563535 R 419947 CDS YP_001281762.1 148660239 5215616 complement(564033..564737) 1 NC_009525.1 TetR family transcriptional regulator 564737 5215616 MRA_0479 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001281762.1 564033 R 419947 CDS YP_001281763.1 148660240 5215617 564874..566244 1 NC_009525.1 hypothetical protein 566244 5215617 MRA_0480 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281763.1 564874 D 419947 CDS YP_001281764.1 148660241 5211813 566331..566753 1 NC_009525.1 PbsX family transcriptional regulator 566753 5211813 MRA_0481 Mycobacterium tuberculosis H37Ra PbsX family transcriptional regulator YP_001281764.1 566331 D 419947 CDS YP_001281765.1 148660242 5211814 567107..567706 1 NC_009525.1 iron-regulated heparin binding hemagglutinin Hbha 567706 hbhA 5211814 hbhA Mycobacterium tuberculosis H37Ra iron-regulated heparin binding hemagglutinin Hbha YP_001281765.1 567107 D 419947 CDS YP_001281766.1 148660243 5211815 567818..568081 1 NC_009525.1 transmembrane protein 568081 5211815 MRA_0483 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281766.1 567818 D 419947 CDS YP_001281767.1 148660244 5211816 568086..568532 1 NC_009525.1 hypothetical protein 568532 5211816 MRA_0484 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281767.1 568086 D 419947 CDS YP_001281768.1 148660245 5211817 568532..569206 1 NC_009525.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 569206 deoC 5211817 deoC Mycobacterium tuberculosis H37Ra deoxyribose-phosphate aldolase YP_001281768.1 568532 D 419947 CDS YP_001281769.1 148660246 5211818 complement(569231..570277) 1 NC_009525.1 hypothetical protein 570277 5211818 MRA_0486 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281769.1 569231 R 419947 CDS YP_001281770.1 148660247 5211819 complement(570274..571116) 1 NC_009525.1 carbon-nitrogen hydrolase 571116 5211819 MRA_0487 Mycobacterium tuberculosis H37Ra carbon-nitrogen hydrolase YP_001281770.1 570274 R 419947 CDS YP_001281771.1 148660248 5212254 complement(571298..571822) 1 NC_009525.1 hypothetical protein 571822 5212254 MRA_0488 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281771.1 571298 R 419947 CDS YP_001281772.1 148660249 5212255 571849..572958 1 NC_009525.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 572958 murB 5212255 murB Mycobacterium tuberculosis H37Ra UDP-N-acetylenolpyruvoylglucosamine reductase YP_001281772.1 571849 D 419947 CDS YP_001281773.1 148660250 5212256 573020..574375 1 NC_009525.1 lipoprotein LprQ 574375 lprQ 5212256 lprQ Mycobacterium tuberculosis H37Ra lipoprotein LprQ YP_001281773.1 573020 D 419947 CDS YP_001281774.1 148660251 5212257 complement(574356..575111) 1 NC_009525.1 short-chain type dehydrogenase/reductase 575111 5212257 MRA_0491 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001281774.1 574356 R 419947 CDS YP_001281775.1 148660252 5212258 575294..576610 1 NC_009525.1 NagC-related protein 576610 5212258 MRA_0492 Mycobacterium tuberculosis H37Ra NagC-related protein YP_001281775.1 575294 D 419947 CDS YP_001281776.1 148660253 5212259 576658..578100 1 NC_009525.1 glycosyl transferase 578100 5212259 MRA_0493 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001281776.1 576658 D 419947 CDS YP_001281777.1 148660254 5212260 578097..578648 1 NC_009525.1 hypothetical protein 578648 5212260 MRA_0494 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281777.1 578097 D 419947 CDS YP_001281778.1 148660255 5212267 578974..579579 1 NC_009525.1 integral membrane protein 579579 5212267 MRA_0495 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281778.1 578974 D 419947 CDS YP_001281779.1 148660256 5212268 579736..580485 1 NC_009525.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 580485 gpmA 5212268 gpmA Mycobacterium tuberculosis H37Ra phosphoglyceromutase YP_001281779.1 579736 D 419947 CDS YP_001281780.1 148660257 5212269 580659..581891 1 NC_009525.1 two component sensor histidine kinase SenX3 581891 senX3 5212269 senX3 Mycobacterium tuberculosis H37Ra two component sensor histidine kinase SenX3 YP_001281780.1 580659 D 419947 CDS YP_001281781.1 148660258 5212270 582119..582802 1 NC_009525.1 two component sensory transduction protein RegX3 582802 regX3 5212270 regX3 Mycobacterium tuberculosis H37Ra two component sensory transduction protein RegX3 YP_001281781.1 582119 D 419947 CDS YP_001281782.1 148660259 5212271 complement(582799..584688) 1 NC_009525.1 GMC-type oxidoreductase 584688 5212271 MRA_0499 Mycobacterium tuberculosis H37Ra GMC-type oxidoreductase YP_001281782.1 582799 R 419947 CDS YP_001281783.1 148660260 5212272 complement(584685..585014) 1 NC_009525.1 hypothetical protein 585014 5212272 MRA_0499A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281783.1 584685 R 419947 CDS YP_001281784.1 148660261 5212273 complement(585011..586000) 1 NC_009525.1 hypothetical protein 586000 5212273 MRA_0500 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281784.1 585011 R 419947 CDS YP_001281785.1 148660262 5215437 586005..586733 1 NC_009525.1 GntR family transcriptional regulator 586733 5215437 MRA_0501 Mycobacterium tuberculosis H37Ra GntR family transcriptional regulator YP_001281785.1 586005 D 419947 CDS YP_001281786.1 148660263 5215438 complement(586734..587624) 1 NC_009525.1 hypothetical protein 587624 5215438 MRA_0502 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281786.1 586734 R 419947 CDS YP_001281787.1 148660264 5215439 587704..588690 1 NC_009525.1 hypothetical protein 588690 5215439 MRA_0503 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281787.1 587704 D 419947 CDS YP_001281788.1 148660265 5215440 588687..589619 1 NC_009525.1 transmembrane protein 589619 5215440 MRA_0504 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281788.1 588687 D 419947 CDS YP_001281789.1 148660266 5215441 589635..590477 1 NC_009525.1 hypothetical protein 590477 5215441 MRA_0505 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281789.1 589635 D 419947 CDS YP_001281790.1 148660267 5215442 590493..591368 1 NC_009525.1 hypothetical protein 591368 5215442 MRA_0506 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281790.1 590493 D 419947 CDS YP_001281791.1 148660268 5214181 591393..592280 1 NC_009525.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 592280 proC 5214181 proC Mycobacterium tuberculosis H37Ra pyrroline-5-carboxylate reductase YP_001281791.1 591393 D 419947 CDS YP_001281792.1 148660269 5214182 592421..592657 1 NC_009525.1 hypothetical protein 592657 5214182 MRA_0508 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281792.1 592421 D 419947 CDS YP_001281793.1 148660270 5214183 592964..594094 1 NC_009525.1 NAD-dependent epimerase/dehydratase 594094 galE2 5214183 galE2 Mycobacterium tuberculosis H37Ra NAD-dependent epimerase/dehydratase YP_001281793.1 592964 D 419947 CDS YP_001281794.1 148660271 5214184 594101..595177 1 NC_009525.1 hypothetical protein 595177 5214184 MRA_0510 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281794.1 594101 D 419947 CDS YP_001281795.1 148660272 5214185 complement(595181..596089) 1 NC_009525.1 cyclopropane-fatty-acyl-phospholipid synthase 2 596089 cmaA2 5214185 cmaA2 Mycobacterium tuberculosis H37Ra cyclopropane-fatty-acyl-phospholipid synthase 2 YP_001281795.1 595181 R 419947 CDS YP_001281796.1 148660273 5214186 complement(596112..596612) 1 NC_009525.1 hypothetical protein 596612 5214186 MRA_0512 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281796.1 596112 R 419947 CDS YP_001281797.1 148660274 5214187 complement(596774..597895) 1 NC_009525.1 o-phosphoserine phosphohydrolase; phosphoserine phosphatase SerB1 597895 serB1 5214187 serB1 Mycobacterium tuberculosis H37Ra phosphoserine phosphatase SerB1 YP_001281797.1 596774 R 419947 CDS YP_001281798.1 148660275 5213066 598069..598512 1 NC_009525.1 membrane protein MmpS2 598512 mmpS2 5213066 mmpS2 Mycobacterium tuberculosis H37Ra membrane protein MmpS2 YP_001281798.1 598069 D 419947 CDS YP_001281799.1 148660276 5213067 598509..601415 1 NC_009525.1 transmembrane transport protein MmpL2 601415 mmpL2 5213067 mmpL2 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL2 YP_001281799.1 598509 D 419947 CDS YP_001281800.1 148660277 5213068 601408..601701 1 NC_009525.1 hypothetical protein 601701 5213068 MRA_0515A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281800.1 601408 D 419947 CDS YP_001281801.1 148660278 5213069 601751..603157 1 NC_009525.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 603157 hemA 5213069 hemA Mycobacterium tuberculosis H37Ra glutamyl-tRNA reductase YP_001281801.1 601751 D 419947 CDS YP_001281802.1 148660279 5213070 603167..604096 1 NC_009525.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 604096 hemC 5213070 hemC Mycobacterium tuberculosis H37Ra porphobilinogen deaminase YP_001281802.1 603167 D 419947 CDS YP_001281803.1 148660280 5213071 604129..605826 1 NC_009525.1 uroporphyrin-III C-methyltransferase 605826 hemD 5213071 hemD Mycobacterium tuberculosis H37Ra uroporphyrin-III C-methyltransferase YP_001281803.1 604129 D 419947 CDS YP_001281804.1 148660281 5213072 605912..606901 1 NC_009525.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 606901 hemB 5213072 hemB Mycobacterium tuberculosis H37Ra delta-aminolevulinic acid dehydratase YP_001281804.1 605912 D 419947 CDS YP_001281805.1 148660282 5212444 606914..607462 1 NC_009525.1 transmembrane protein 607462 5212444 MRA_0520 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281805.1 606914 D 419947 CDS YP_001281806.1 148660283 5212445 607459..607758 1 NC_009525.1 transmembrane protein 607758 5212445 MRA_0521 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281806.1 607459 D 419947 CDS YP_001281807.1 148660284 5212446 607861..609372 1 NC_009525.1 hypothetical protein 609372 5212446 MRA_0522 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281807.1 607861 D 419947 CDS YP_001281808.1 148660285 5212447 complement(609369..609845) 1 NC_009525.1 hypothetical protein 609845 5212447 MRA_0523 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281808.1 609369 R 419947 CDS YP_001281809.1 148660286 5212448 610056..611366 1 NC_009525.1 membrane acyltransferase 611366 5212448 MRA_0524 Mycobacterium tuberculosis H37Ra membrane acyltransferase YP_001281809.1 610056 D 419947 CDS YP_001281810.1 148660287 5212449 611498..612193 1 NC_009525.1 hypothetical protein 612193 5212449 MRA_0525 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281810.1 611498 D 419947 CDS YP_001281811.1 148660288 5212450 complement(612482..613384) 1 NC_009525.1 hypothetical protein 613384 5212450 MRA_0526 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281811.1 612482 R 419947 CDS YP_001281812.1 148660289 5214840 613565..613915 1 NC_009525.1 methyltransferase/methylase 613915 5214840 MRA_0527 Mycobacterium tuberculosis H37Ra methyltransferase/methylase YP_001281812.1 613565 D 419947 CDS YP_001281813.1 148660290 5214841 613908..614213 1 NC_009525.1 hypothetical protein 614213 5214841 MRA_0528 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281813.1 613908 D 419947 CDS YP_001281814.1 148660291 5214842 614348..615652 1 NC_009525.1 4-amino butyrate transport carrier; gaba permease GabP 615652 gabP 5214842 gabP Mycobacterium tuberculosis H37Ra gaba permease GabP YP_001281814.1 614348 D 419947 CDS YP_001281815.1 148660292 5214843 complement(615636..616031) 1 NC_009525.1 hypothetical protein 616031 5214843 MRA_0530 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281815.1 615636 R 419947 CDS YP_001281816.1 148660293 5214844 616145..617533 1 NC_009525.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 617533 hemL 5214844 hemL Mycobacterium tuberculosis H37Ra glutamate-1-semialdehyde aminotransferase YP_001281816.1 616145 D 419947 CDS YP_001281817.1 148660294 5214845 617533..618141 1 NC_009525.1 hypothetical protein 618141 5214845 MRA_0532 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281817.1 617533 D 419947 CDS YP_001281818.1 148660295 5212139 618156..618806 1 NC_009525.1 thiol-disulfide interchange protein; thioredoxin protein 618806 5212139 MRA_0533 Mycobacterium tuberculosis H37Ra thioredoxin protein YP_001281818.1 618156 D 419947 CDS YP_001281819.1 148660296 5212140 618803..619582 1 NC_009525.1 cytochrome C biogenesis protein 619582 ccdA 5212140 ccdA Mycobacterium tuberculosis H37Ra cytochrome C biogenesis protein YP_001281819.1 618803 D 419947 CDS YP_001281820.1 148660297 5212141 619615..621204 1 NC_009525.1 transmembrane protein 621204 5212141 MRA_0535 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281820.1 619615 D 419947 CDS YP_001281821.1 148660298 5212142 621201..622175 1 NC_009525.1 cytochrome c assembly family protein 622175 ccsA 5212142 ccsA Mycobacterium tuberculosis H37Ra cytochrome c assembly family protein YP_001281821.1 621201 D 419947 CDS YP_001281822.1 148660299 5212143 622217..623434 1 NC_009525.1 hypothetical protein 623434 5212143 MRA_0537 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281822.1 622217 D 419947 CDS YP_001281823.1 148660300 5212144 623639..623956 1 NC_009525.1 hypothetical protein 623956 5212144 MRA_0538 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281823.1 623639 D 419947 CDS YP_001281824.1 148660301 5212145 624103..625887 1 NC_009525.1 PE-PGRS family protein 625887 5212145 MRA_0539 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001281824.1 624103 D 419947 CDS YP_001281825.1 148660302 5215061 complement(625783..626790) 1 NC_009525.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 626790 fabH 5215061 fabH Mycobacterium tuberculosis H37Ra 3-oxoacyl-ACP synthase YP_001281825.1 625783 R 419947 CDS YP_001281826.1 148660303 5215062 complement(626872..627750) 1 NC_009525.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 627750 menA 5215062 menA Mycobacterium tuberculosis H37Ra 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001281826.1 626872 R 419947 CDS YP_001281827.1 148660304 5215063 627767..628561 1 NC_009525.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate; 5'-methylthioadenosine phosphorylase 628561 pnp 5215063 pnp Mycobacterium tuberculosis H37Ra 5'-methylthioadenosine phosphorylase YP_001281827.1 627767 D 419947 CDS YP_001281828.1 148660305 5215064 628558..629598 1 NC_009525.1 NAD-dependent epimerase/dehydratase 629598 galE3 5215064 galE3 Mycobacterium tuberculosis H37Ra NAD-dependent epimerase/dehydratase YP_001281828.1 628558 D 419947 CDS YP_001281829.1 148660306 5215065 complement(629608..631041) 1 NC_009525.1 integral membrane protein 631041 5215065 MRA_0544 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281829.1 629608 R 419947 CDS YP_001281830.1 148660307 5215066 631350..632996 1 NC_009525.1 hypothetical protein 632996 5215066 MRA_0545 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281830.1 631350 D 419947 CDS YP_001281831.1 148660308 5215067 633029..633685 1 NC_009525.1 glycosyl transferase 633685 5215067 MRA_0546 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001281831.1 633029 D 419947 CDS YP_001281832.1 148660309 5215414 633682..634344 1 NC_009525.1 hypothetical protein 634344 5215414 MRA_0547 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281832.1 633682 D 419947 CDS YP_001281833.1 148660310 5215415 complement(634365..635714) 1 NC_009525.1 integral membrane protein 635714 5215415 MRA_0548 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281833.1 634365 R 419947 CDS YP_001281834.1 148660311 5215416 complement(635726..636814) 1 NC_009525.1 O-succinylbenzoic acid--CoA ligase 636814 menE 5215416 menE Mycobacterium tuberculosis H37Ra O-succinylbenzoic acid--CoA ligase YP_001281834.1 635726 R 419947 CDS YP_001281835.1 148660312 5215417 complement(636883..637185) 1 NC_009525.1 hypothetical protein 637185 5215417 MRA_0550 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281835.1 636883 R 419947 CDS YP_001281836.1 148660313 5215418 complement(637245..637523) 1 NC_009525.1 transmembrane protein 637523 5215418 MRA_0551 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281836.1 637245 R 419947 CDS YP_001281837.1 148660314 5215419 complement(637520..638773) 1 NC_009525.1 low-affinity inorganic phosphate transporter integral membrane protein PitA 638773 pitA 5215419 pitA Mycobacterium tuberculosis H37Ra low-affinity inorganic phosphate transporter integral membrane protein PitA YP_001281837.1 637520 R 419947 CDS YP_001281838.1 148660315 5215420 complement(638893..639279) 1 NC_009525.1 hypothetical protein 639279 5215420 MRA_0553 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281838.1 638893 R 419947 CDS YP_001281839.1 148660316 5211627 complement(639342..640349) 1 NC_009525.1 short chain dehydrogenase 640349 5211627 MRA_0554 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001281839.1 639342 R 419947 CDS YP_001281840.1 148660317 5211628 complement(640322..641266) 1 NC_009525.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 641266 menB 5211628 menB Mycobacterium tuberculosis H37Ra naphthoate synthase YP_001281840.1 640322 R 419947 CDS YP_001281841.1 148660318 5211629 complement(641538..641951) 1 NC_009525.1 hypothetical protein 641951 5211629 MRA_0556 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281841.1 641538 R 419947 CDS YP_001281842.1 148660319 5211630 complement(641948..642214) 1 NC_009525.1 hypothetical protein 642214 5211630 MRA_0557 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281842.1 641948 R 419947 CDS YP_001281843.1 148660320 5211631 complement(642406..644121) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 644121 fadD8 5211631 fadD8 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001281843.1 642406 R 419947 CDS YP_001281844.1 148660321 5211632 644199..645803 1 NC_009525.1 hypothetical protein 645803 5211632 MRA_0559 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281844.1 644199 D 419947 CDS YP_001281845.1 148660322 5211633 645800..646780 1 NC_009525.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 646780 menC 5211633 menC Mycobacterium tuberculosis H37Ra O-succinylbenzoate synthase YP_001281845.1 645800 D 419947 CDS YP_001281846.1 148660323 5214044 646777..647565 1 NC_009525.1 bromoperoxidase 647565 bpoC 5214044 bpoC Mycobacterium tuberculosis H37Ra bromoperoxidase YP_001281846.1 646777 D 419947 CDS YP_001281847.1 148660324 5214045 647608..649272 1 NC_009525.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 649272 menD 5214045 menD Mycobacterium tuberculosis H37Ra 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_001281847.1 647608 D 419947 CDS YP_001281848.1 148660325 5214046 649269..649784 1 NC_009525.1 transmembrane protein 649784 5214046 MRA_0563 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281848.1 649269 D 419947 CDS YP_001281849.1 148660326 5214047 649846..650982 1 NC_009525.1 mannosyltransferase 650982 pimB 5214047 pimB Mycobacterium tuberculosis H37Ra mannosyltransferase YP_001281849.1 649846 D 419947 CDS YP_001281850.1 148660327 5214048 650999..651703 1 NC_009525.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 651703 ubiE 5214048 ubiE Mycobacterium tuberculosis H37Ra ubiquinone/menaquinone biosynthesis methyltransferase YP_001281850.1 650999 D 419947 CDS YP_001281851.1 148660328 5214049 complement(651717..652055) 1 NC_009525.1 hypothetical protein 652055 5214049 MRA_0566 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281851.1 651717 R 419947 CDS YP_001281852.1 148660329 5214128 complement(652089..652814) 1 NC_009525.1 benzoquinone methyltransferase 652814 5214128 MRA_0567 Mycobacterium tuberculosis H37Ra benzoquinone methyltransferase YP_001281852.1 652089 R 419947 CDS YP_001281853.1 148660330 5214129 complement(652839..654065) 1 NC_009525.1 oxidoreductase 654065 5214129 MRA_0568 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001281853.1 652839 R 419947 CDS YP_001281854.1 148660331 5214130 654081..655088 1 NC_009525.1 polyprenyl-diphosphate synthase GrcC1 655088 grcC1 5214130 grcC1 Mycobacterium tuberculosis H37Ra polyprenyl-diphosphate synthase GrcC1 YP_001281854.1 654081 D 419947 CDS YP_001281855.1 148660332 5214131 655189..656049 1 NC_009525.1 metalloprotease; heat shock protein HtpX 656049 htpX 5214131 htpX Mycobacterium tuberculosis H37Ra heat shock protein HtpX YP_001281855.1 655189 D 419947 CDS YP_001281856.1 148660333 5214132 complement(656234..657259) 1 NC_009525.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 657259 gpsA1 5214132 gpsA1 Mycobacterium tuberculosis H37Ra NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001281856.1 656234 R 419947 CDS YP_001281857.1 148660334 5214133 complement(657320..658780) 1 NC_009525.1 monooxygenase 658780 5214133 MRA_0572 Mycobacterium tuberculosis H37Ra monooxygenase YP_001281857.1 657320 R 419947 CDS YP_001281858.1 148660335 5214134 complement(658858..659349) 1 NC_009525.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 659349 5214134 MRA_0573 Mycobacterium tuberculosis H37Ra nucleotide-binding protein YP_001281858.1 658858 R 419947 CDS YP_001281859.1 148660336 5214955 659631..660650 1 NC_009525.1 tetracenpmycin polyketide synthesis 8-o-methyltransferase 660650 5214955 MRA_0574 Mycobacterium tuberculosis H37Ra tetracenpmycin polyketide synthesis 8-o-methyltransferase YP_001281859.1 659631 D 419947 CDS YP_001281860.1 148660337 5214956 660760..662178 1 NC_009525.1 cytochrome p450 135B1 Cyp135B1 662178 cyp135B1 5214956 cyp135B1 Mycobacterium tuberculosis H37Ra cytochrome p450 135B1 Cyp135B1 YP_001281860.1 660760 D 419947 CDS YP_001281861.1 148660338 5214957 662313..662579 1 NC_009525.1 hypothetical protein 662579 5214957 MRA_0576 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281861.1 662313 D 419947 CDS YP_001281862.1 148660339 5214958 662605..664683 1 NC_009525.1 ribonucleoside-diphosphate reductase subunit alpha 664683 nrdZ 5214958 nrdZ Mycobacterium tuberculosis H37Ra ribonucleoside-diphosphate reductase subunit alpha YP_001281862.1 662605 D 419947 CDS YP_001281863.1 148660340 5214959 complement(664797..666128) 1 NC_009525.1 hypothetical protein 666128 5214959 MRA_0578 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281863.1 664797 R 419947 CDS YP_001281864.1 148660341 5214968 complement(666352..666693) 1 NC_009525.1 hypothetical protein 666693 5214968 MRA_0579 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281864.1 666352 R 419947 CDS YP_001281865.1 148660342 5214969 complement(667161..668552) 1 NC_009525.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 668552 5214969 MRA_0580 Mycobacterium tuberculosis H37Ra nicotinate phosphoribosyltransferase YP_001281865.1 667161 R 419947 CDS YP_001281866.1 148660343 5214970 complement(668562..669704) 1 NC_009525.1 hypothetical protein 669704 5214970 MRA_0581 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281866.1 668562 R 419947 CDS YP_001281867.1 148660344 5214971 complement(669889..671055) 1 NC_009525.1 hypothetical protein 671055 5214971 MRA_0582 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281867.1 669889 R 419947 CDS YP_001281868.1 148660345 5214972 671158..672462 1 NC_009525.1 transcription regulator ArsR 672462 5214972 MRA_0583 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001281868.1 671158 D 419947 CDS YP_001281869.1 148660346 5214973 672476..673261 1 NC_009525.1 hypothetical protein 673261 5214973 MRA_0584 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281869.1 672476 D 419947 CDS YP_001281870.1 148660347 5214974 complement(673306..677226) 1 NC_009525.1 PE-PGRS family protein 677226 5214974 MRA_0585 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001281870.1 673306 R 419947 CDS YP_001281871.1 148660348 5213148 677548..678306 1 NC_009525.1 hypothetical protein 678306 5213148 MRA_0586 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281871.1 677548 D 419947 CDS YP_001281872.1 148660349 5213149 complement(678435..678926) 1 NC_009525.1 hypothetical protein 678926 5213149 MRA_0587 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281872.1 678435 R 419947 CDS YP_001281873.1 148660350 5213150 679020..679235 1 NC_009525.1 hypothetical protein 679235 5213150 MRA_0588 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281873.1 679020 D 419947 CDS YP_001281874.1 148660351 5213151 complement(679037..679885) 1 NC_009525.1 hypothetical protein 679885 5213151 MRA_0589 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281874.1 679037 R 419947 CDS YP_001281875.1 148660352 5213152 complement(679699..680385) 1 NC_009525.1 lipoprotein LpqN 680385 lpqN 5213152 lpqN Mycobacterium tuberculosis H37Ra lipoprotein LpqN YP_001281875.1 679699 R 419947 CDS YP_001281876.1 148660353 5213153 680539..683172 1 NC_009525.1 hypothetical protein 683172 5213153 MRA_0591 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281876.1 680539 D 419947 CDS YP_001281877.1 148660354 5211746 complement(683195..685582) 1 NC_009525.1 integral membrane protein 685582 5211746 MRA_0592 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281877.1 683195 R 419947 CDS YP_001281878.1 148660355 5211747 685720..686442 1 NC_009525.1 GntR family transcriptional regulator 686442 5211747 MRA_0593 Mycobacterium tuberculosis H37Ra GntR family transcriptional regulator YP_001281878.1 685720 D 419947 CDS YP_001281879.1 148660356 5211748 686439..687236 1 NC_009525.1 hypothetical protein 687236 yrbE2A 5211748 yrbE2A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281879.1 686439 D 419947 CDS YP_001281880.1 148660357 5211749 687238..688125 1 NC_009525.1 hypothetical protein 688125 yrbE2B 5211749 yrbE2B Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281880.1 687238 D 419947 CDS YP_001281881.1 148660358 5211750 688131..689345 1 NC_009525.1 MCE-family protein Mce2A 689345 mce2A 5211750 mce2A Mycobacterium tuberculosis H37Ra MCE-family protein Mce2A YP_001281881.1 688131 D 419947 CDS YP_001281882.1 148660359 5211751 689342..690169 1 NC_009525.1 MCE-family protein Mce2B 690169 mce2B 5211751 mce2B Mycobacterium tuberculosis H37Ra MCE-family protein Mce2B YP_001281882.1 689342 D 419947 CDS YP_001281883.1 148660360 5211752 690118..690372 1 NC_009525.1 MCE family-like protein 690372 5211752 MRA_0598 Mycobacterium tuberculosis H37Ra MCE family-like protein YP_001281883.1 690118 D 419947 CDS YP_001281884.1 148660361 5211767 690369..691814 1 NC_009525.1 MCE-family protein Mce2C 691814 mce2C 5211767 mce2C Mycobacterium tuberculosis H37Ra MCE-family protein Mce2C YP_001281884.1 690369 D 419947 CDS YP_001281885.1 148660362 5211768 691811..693337 1 NC_009525.1 MCE-family protein Mce2D 693337 mce2D 5211768 mce2D Mycobacterium tuberculosis H37Ra MCE-family protein Mce2D YP_001281885.1 691811 D 419947 CDS YP_001281886.1 148660363 5211769 693334..694542 1 NC_009525.1 MCE family lipoprotein LprL 694542 lprL 5211769 lprL Mycobacterium tuberculosis H37Ra MCE family lipoprotein LprL YP_001281886.1 693334 D 419947 CDS YP_001281887.1 148660364 5211770 694547..696097 1 NC_009525.1 MCE-family protein Mce2F 696097 mce2F 5211770 mce2F Mycobacterium tuberculosis H37Ra MCE-family protein Mce2F YP_001281887.1 694547 D 419947 CDS YP_001281888.1 148660365 5211771 complement(696149..696541) 1 NC_009525.1 hypothetical protein 696541 5211771 MRA_0603 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281888.1 696149 R 419947 CDS YP_001281889.1 148660366 5211772 complement(696538..696795) 1 NC_009525.1 hypothetical protein 696795 5211772 MRA_0604 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281889.1 696538 R 419947 CDS YP_001281890.1 148660367 5211773 complement(696978..698213) 1 NC_009525.1 hypothetical protein 698213 5211773 MRA_0605 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281890.1 696978 R 419947 CDS YP_001281891.1 148660368 5213607 complement(698464..698877) 1 NC_009525.1 hypothetical protein 698877 5213607 MRA_0606 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281891.1 698464 R 419947 CDS YP_001281892.1 148660369 5213608 complement(698874..699110) 1 NC_009525.1 hypothetical protein 699110 5213608 MRA_0607 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281892.1 698874 R 419947 CDS YP_001281893.1 148660370 5213609 complement(699214..699720) 1 NC_009525.1 two component sensor kinase 699720 5213609 MRA_0608 Mycobacterium tuberculosis H37Ra two component sensor kinase YP_001281893.1 699214 R 419947 CDS YP_001281894.1 148660371 5213610 complement(699834..700304) 1 NC_009525.1 two component sensor kinase 700304 5213610 MRA_0608A Mycobacterium tuberculosis H37Ra two component sensor kinase YP_001281894.1 699834 R 419947 CDS YP_001281895.1 148660372 5213611 complement(700348..701109) 1 NC_009525.1 two component DNA binding transcriptional regulatory protein TcrA 701109 tcrA 5213611 tcrA Mycobacterium tuberculosis H37Ra two component DNA binding transcriptional regulatory protein TcrA YP_001281895.1 700348 R 419947 CDS YP_001281896.1 148660373 5213612 701166..701477 1 NC_009525.1 hypothetical protein 701477 5213612 MRA_0610 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281896.1 701166 D 419947 CDS YP_001281897.1 148660374 5213613 701549..702499 1 NC_009525.1 lipoprotein LpqO 702499 lpqO 5213613 lpqO Mycobacterium tuberculosis H37Ra lipoprotein LpqO YP_001281897.1 701549 D 419947 CDS YP_001281898.1 148660375 5213550 702716..703324 1 NC_009525.1 IS1536 resolvase 703324 5213550 MRA_0612 Mycobacterium tuberculosis H37Ra IS1536 resolvase YP_001281898.1 702716 D 419947 CDS YP_001281899.1 148660376 5213551 703326..704069 1 NC_009525.1 truncated IS1536 transposase 704069 5213551 MRA_0613 Mycobacterium tuberculosis H37Ra truncated IS1536 transposase YP_001281899.1 703326 D 419947 CDS YP_001281900.1 148660377 5213552 704123..704509 1 NC_009525.1 hypothetical protein 704509 5213552 MRA_0614 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281900.1 704123 D 419947 CDS YP_001281901.1 148660378 5213553 704554..704799 1 NC_009525.1 hypothetical protein 704799 5213553 MRA_0615 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281901.1 704554 D 419947 CDS YP_001281902.1 148660379 5213554 704796..705197 1 NC_009525.1 hypothetical protein 705197 5213554 MRA_0616 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281902.1 704796 D 419947 CDS YP_001281903.1 148660380 5213555 705140..705367 1 NC_009525.1 hypothetical protein 705367 5213555 MRA_0617 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281903.1 705140 D 419947 CDS YP_001281904.1 148660381 5213556 705650..706069 1 NC_009525.1 hypothetical protein 706069 5213556 MRA_0618 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281904.1 705650 D 419947 CDS YP_001281905.1 148660382 5215231 complement(706062..707219) 1 NC_009525.1 hypothetical protein 707219 5215231 MRA_0619 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281905.1 706062 R 419947 CDS YP_001281906.1 148660383 5215232 complement(707271..707654) 1 NC_009525.1 hypothetical protein 707654 5215232 MRA_0620 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281906.1 707271 R 419947 CDS YP_001281907.1 148660384 5215233 707634..708239 1 NC_009525.1 hypothetical protein 708239 5215233 MRA_0621 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281907.1 707634 D 419947 CDS YP_001281908.1 148660385 5215234 complement(708258..710825) 1 NC_009525.1 hypothetical protein 710825 5215234 MRA_0622 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281908.1 708258 R 419947 CDS YP_001281909.1 148660386 5215235 710666..711658 1 NC_009525.1 hypothetical protein 711658 5215235 MRA_0623 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281909.1 710666 D 419947 CDS YP_001281910.1 148660387 5215236 711655..711897 1 NC_009525.1 integral membrane protein 711897 5215236 MRA_0624 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281910.1 711655 D 419947 CDS YP_001281911.1 148660388 5215237 complement(711894..712160) 1 NC_009525.1 hypothetical protein 712160 5215237 MRA_0625 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281911.1 711894 R 419947 CDS YP_001281912.1 148660389 5212300 712316..712717 1 NC_009525.1 hypothetical protein 712717 5212300 MRA_0626 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281912.1 712316 D 419947 CDS YP_001281913.1 148660390 5212301 712846..713541 1 NC_009525.1 galactose-1-phosphate uridylyltransferase GalTa 713541 galTa 5212301 galTa Mycobacterium tuberculosis H37Ra galactose-1-phosphate uridylyltransferase GalTa YP_001281913.1 712846 D 419947 CDS YP_001281914.1 148660391 5212302 713538..714029 1 NC_009525.1 galactose-1-phosphate uridylyltransferase GalTb 714029 galTb 5212302 galTb Mycobacterium tuberculosis H37Ra galactose-1-phosphate uridylyltransferase GalTb YP_001281914.1 713538 D 419947 CDS YP_001281915.1 148660392 5212303 714026..715117 1 NC_009525.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 715117 galK 5212303 galK Mycobacterium tuberculosis H37Ra galactokinase YP_001281915.1 714026 D 419947 CDS YP_001281916.1 148660393 5212304 715512..716576 1 NC_009525.1 hypothetical protein 716576 5212304 MRA_0630 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281916.1 715512 D 419947 CDS YP_001281917.1 148660394 5212305 716680..717627 1 NC_009525.1 hypothetical protein 717627 5212305 MRA_0631 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281917.1 716680 D 419947 CDS YP_001281918.1 148660395 5212642 717720..717974 1 NC_009525.1 hypothetical protein 717974 5212642 MRA_0632 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281918.1 717720 D 419947 CDS YP_001281919.1 148660396 5212643 717974..718369 1 NC_009525.1 hypothetical protein 718369 5212643 MRA_0633 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281919.1 717974 D 419947 CDS YP_001281920.1 148660397 5212644 complement(718463..719203) 1 NC_009525.1 transmembrane protein 719203 5212644 MRA_0634 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281920.1 718463 R 419947 CDS YP_001281921.1 148660398 5212645 719335..719595 1 NC_009525.1 hypothetical protein 719595 5212645 MRA_0635 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281921.1 719335 D 419947 CDS YP_001281922.1 148660399 5212646 719592..719999 1 NC_009525.1 hypothetical protein 719999 5212646 MRA_0636 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281922.1 719592 D 419947 CDS YP_001281923.1 148660400 5212647 complement(720071..721222) 1 NC_009525.1 hypothetical protein 721222 5212647 MRA_0637 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281923.1 720071 R 419947 CDS YP_001281924.1 148660401 5212648 complement(721315..723042) 1 NC_009525.1 RecD; exonuclease V alpha chain 723042 recD 5212648 recD Mycobacterium tuberculosis H37Ra exonuclease V alpha chain YP_001281924.1 721315 R 419947 CDS YP_001281925.1 148660402 5211829 complement(723039..726323) 1 NC_009525.1 exodeoxyribonuclease V subunit beta 726323 recB 5211829 recB Mycobacterium tuberculosis H37Ra exodeoxyribonuclease V subunit beta YP_001281925.1 723039 R 419947 CDS YP_001281926.1 148660403 5211830 complement(726323..729616) 1 NC_009525.1 exodeoxyribonuclease V subunit gamma 729616 recC 5211830 recC Mycobacterium tuberculosis H37Ra exodeoxyribonuclease V subunit gamma YP_001281926.1 726323 R 419947 CDS YP_001281927.1 148660404 5211831 complement(729893..730588) 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 730588 echA3 5211831 echA3 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001281927.1 729893 R 419947 CDS YP_001281928.1 148660405 5211832 complement(730637..731476) 1 NC_009525.1 hypothetical protein 731476 5211832 MRA_0642 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281928.1 730637 R 419947 CDS YP_001281929.1 148660406 5211833 complement(731630..732343) 1 NC_009525.1 glyoxalase II 732343 5211833 MRA_0643 Mycobacterium tuberculosis H37Ra glyoxalase II YP_001281929.1 731630 R 419947 CDS YP_001281930.1 148660407 5211834 732423..732674 1 NC_009525.1 hypothetical protein 732674 5211834 MRA_0644 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281930.1 732423 D 419947 CDS YP_001281931.1 148660408 5213987 733022..733189 1 NC_009525.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 733189 rpmG 5213987 rpmG Mycobacterium tuberculosis H37Ra 50S ribosomal protein L33 YP_001281931.1 733022 D 419947 CDS YP_001281932.1 148660409 5213988 733240..733698 1 NC_009525.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadA 733698 5213988 MRA_0646 Mycobacterium tuberculosis H37Ra (3R)-hydroxyacyl-ACP dehydratase subunit HadA YP_001281932.1 733240 D 419947 CDS YP_001281933.1 148660410 5213989 733698..734126 1 NC_009525.1 functions as a heterodimer along with HadA or HadC in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadB 734126 5213989 MRA_0647 Mycobacterium tuberculosis H37Ra (3R)-hydroxyacyl-ACP dehydratase subunit HadB YP_001281933.1 733698 D 419947 CDS YP_001281934.1 148660411 5213990 734212..734631 1 NC_009525.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadC 734631 5213990 MRA_0648 Mycobacterium tuberculosis H37Ra (3R)-hydroxyacyl-ACP dehydratase subunit HadC YP_001281934.1 734212 D 419947 CDS YP_001281935.1 148660412 5215697 735043..735528 1 NC_009525.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 735528 secE 5215697 secE Mycobacterium tuberculosis H37Ra preprotein translocase subunit SecE YP_001281935.1 735043 D 419947 CDS YP_001281936.1 148660413 5215698 735560..736276 1 NC_009525.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 736276 nusG 5215698 nusG Mycobacterium tuberculosis H37Ra transcription antitermination protein NusG YP_001281936.1 735560 D 419947 CDS YP_001281937.1 148660414 5215699 736328..736756 1 NC_009525.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 736756 rplK 5215699 rplK Mycobacterium tuberculosis H37Ra 50S ribosomal protein L11 YP_001281937.1 736328 D 419947 CDS YP_001281938.1 148660415 5215700 736823..737530 1 NC_009525.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 737530 rplA 5215700 rplA Mycobacterium tuberculosis H37Ra 50S ribosomal protein L1 YP_001281938.1 736823 D 419947 CDS YP_001281939.1 148660416 5215701 complement(737604..738509) 1 NC_009525.1 methoxy mycolic acid synthase 4 738509 mmaA4 5215701 mmaA4 Mycobacterium tuberculosis H37Ra methoxy mycolic acid synthase 4 YP_001281939.1 737604 R 419947 CDS YP_001281940.1 148660417 5211739 complement(738574..739455) 1 NC_009525.1 methoxy mycolic acid synthase 3 739455 mmaA3 5211739 mmaA3 Mycobacterium tuberculosis H37Ra methoxy mycolic acid synthase 3 YP_001281940.1 738574 R 419947 CDS YP_001281941.1 148660418 5211740 complement(739603..740466) 1 NC_009525.1 methoxy mycolic acid synthase 2 740466 mmaA2 5211740 mmaA2 Mycobacterium tuberculosis H37Ra methoxy mycolic acid synthase 2 YP_001281941.1 739603 R 419947 CDS YP_001281942.1 148660419 5211741 complement(740633..741493) 1 NC_009525.1 methoxy mycolic acid synthase 1 741493 mmaA1 5211741 mmaA1 Mycobacterium tuberculosis H37Ra methoxy mycolic acid synthase 1 YP_001281942.1 740633 R 419947 CDS YP_001281943.1 148660420 5211742 complement(741540..742445) 1 NC_009525.1 hypothetical protein 742445 lipG 5211742 lipG Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281943.1 741540 R 419947 CDS YP_001281944.1 148660421 5211743 complement(742457..743923) 1 NC_009525.1 hypothetical protein 743923 5211743 MRA_0658 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281944.1 742457 R 419947 CDS YP_001281945.1 148660422 5211744 744025..747672 1 NC_009525.1 alpha-mannosidase 747672 5211744 MRA_0659 Mycobacterium tuberculosis H37Ra alpha-mannosidase YP_001281945.1 744025 D 419947 CDS YP_001281946.1 148660423 5211745 747669..748343 1 NC_009525.1 malonyl CoA acyl carrier protein transacylase FabD2 748343 fabD2 5211745 fabD2 Mycobacterium tuberculosis H37Ra malonyl CoA acyl carrier protein transacylase FabD2 YP_001281946.1 747669 D 419947 CDS YP_001281947.1 148660424 5213769 748343..749251 1 NC_009525.1 glucokinase 749251 5213769 MRA_0661 Mycobacterium tuberculosis H37Ra glucokinase YP_001281947.1 748343 D 419947 CDS YP_001281948.1 148660425 5213770 749582..750118 1 NC_009525.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 750118 rplJ 5213770 rplJ Mycobacterium tuberculosis H37Ra 50S ribosomal protein L10 YP_001281948.1 749582 D 419947 CDS YP_001281949.1 148660426 5213771 750155..750547 1 NC_009525.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 750547 rplL 5213771 rplL Mycobacterium tuberculosis H37Ra 50S ribosomal protein L7/L12 YP_001281949.1 750155 D 419947 CDS YP_001281950.1 148660427 5213772 complement(750540..751235) 1 NC_009525.1 transcriptional repressor 751235 5213772 MRA_0664 Mycobacterium tuberculosis H37Ra transcriptional repressor YP_001281950.1 750540 R 419947 CDS YP_001281951.1 148660428 5213773 751306..752811 1 NC_009525.1 dioxygenase 752811 5213773 MRA_0665 Mycobacterium tuberculosis H37Ra dioxygenase YP_001281951.1 751306 D 419947 CDS YP_001281952.1 148660429 5213774 752823..753902 1 NC_009525.1 ribonucleotide ABC transporter ATP-binding protein Mkl 753902 mkl 5213774 mkl Mycobacterium tuberculosis H37Ra ribonucleotide ABC transporter ATP-binding protein Mkl YP_001281952.1 752823 D 419947 CDS YP_001281953.1 148660430 5213775 complement(754290..754673) 1 NC_009525.1 hypothetical protein 754673 5213775 MRA_0667 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281953.1 754290 R 419947 CDS YP_001281954.1 148660431 5212451 complement(754768..754923) 1 NC_009525.1 hypothetical protein 754923 5212451 MRA_0667A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281954.1 754768 R 419947 CDS YP_001281955.1 148660432 5212452 complement(754999..755715) 1 NC_009525.1 integral membrane protein 755715 5212452 MRA_0668 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001281955.1 754999 R 419947 CDS YP_001281956.1 148660433 5212453 complement(755991..756299) 1 NC_009525.1 hypothetical protein 756299 5212453 MRA_0669 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281956.1 755991 R 419947 CDS YP_001281957.1 148660434 5212454 complement(756286..756531) 1 NC_009525.1 hypothetical protein 756531 5212454 MRA_0670 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281957.1 756286 R 419947 CDS YP_001281958.1 148660435 5212455 complement(756641..757078) 1 NC_009525.1 hypothetical protein 757078 5212455 MRA_0671 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281958.1 756641 R 419947 CDS YP_001281959.1 148660436 5212456 complement(757075..757443) 1 NC_009525.1 hypothetical protein 757443 5212456 MRA_0672 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281959.1 757075 R 419947 CDS YP_001281960.1 148660437 5212457 757443..759806 1 NC_009525.1 arylsulfatase 759806 atsD 5212457 atsD Mycobacterium tuberculosis H37Ra arylsulfatase YP_001281960.1 757443 D 419947 CDS YP_001281961.1 148660438 5211642 759838..760110 1 NC_009525.1 hypothetical protein 760110 5211642 MRA_0673A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281961.1 759838 D 419947 CDS YP_001281962.1 148660439 5211643 760107..760445 1 NC_009525.1 hypothetical protein 760445 5211643 MRA_0674 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281962.1 760107 D 419947 CDS YP_001281963.1 148660440 5211644 760442..760615 1 NC_009525.1 hypothetical protein 760615 5211644 MRA_0675 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281963.1 760442 D 419947 CDS YP_001281964.1 148660441 5211645 761113..764631 1 NC_009525.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 764631 rpoB 5211645 rpoB Mycobacterium tuberculosis H37Ra DNA-directed RNA polymerase subunit beta YP_001281964.1 761113 D 419947 CDS YP_001281965.1 148660442 5211646 764676..768626 1 NC_009525.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 768626 rpoC 5211646 rpoC Mycobacterium tuberculosis H37Ra DNA-directed RNA polymerase subunit beta' YP_001281965.1 764676 D 419947 CDS YP_001281966.1 148660443 5211647 complement(768623..769126) 1 NC_009525.1 hypothetical protein 769126 5211647 MRA_0678 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281966.1 768623 R 419947 CDS YP_001281967.1 148660444 5211648 complement(768990..770903) 1 NC_009525.1 hydrolase 770903 5211648 MRA_0679 Mycobacterium tuberculosis H37Ra hydrolase YP_001281967.1 768990 R 419947 CDS YP_001281968.1 148660445 5213474 771098..771856 1 NC_009525.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 771856 end 5213474 end Mycobacterium tuberculosis H37Ra endonuclease IV YP_001281968.1 771098 D 419947 CDS YP_001281969.1 148660446 5213475 771888..772730 1 NC_009525.1 lipoprotein LpqP 772730 lpqP 5213475 lpqP Mycobacterium tuberculosis H37Ra lipoprotein LpqP YP_001281969.1 771888 D 419947 CDS YP_001281970.1 148660447 5213476 772790..774418 1 NC_009525.1 acyl-CoA dehydrogenase 774418 fadE8 5213476 fadE8 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001281970.1 772790 D 419947 CDS YP_001281971.1 148660448 5213477 774429..775367 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 775367 echA4 5213477 echA4 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001281971.1 774429 D 419947 CDS YP_001281972.1 148660449 5213478 775370..776092 1 NC_009525.1 hypothetical protein 776092 5213478 MRA_0684 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281972.1 775370 D 419947 CDS YP_001281973.1 148660450 5213479 776089..776880 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 776880 echA5 5213479 echA5 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001281973.1 776089 D 419947 CDS YP_001281974.1 148660451 5215277 complement(776892..779786) 1 NC_009525.1 transmembrane transport protein MmpL5 779786 mmpL5 5215277 mmpL5 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL5 YP_001281974.1 776892 R 419947 CDS YP_001281975.1 148660452 5215278 complement(779783..780211) 1 NC_009525.1 hypothetical protein 780211 5215278 MRA_0687 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281975.1 779783 R 419947 CDS YP_001281976.1 148660453 5215279 780296..780793 1 NC_009525.1 hypothetical protein 780793 5215279 MRA_0687A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281976.1 780296 D 419947 CDS YP_001281977.1 148660454 5215280 complement(780849..781346) 1 NC_009525.1 threonine rich protein 781346 5215280 MRA_0688 Mycobacterium tuberculosis H37Ra threonine rich protein YP_001281977.1 780849 R 419947 CDS YP_001281978.1 148660455 5215281 complement(781348..781722) 1 NC_009525.1 transmembrane protein 781722 5215281 MRA_0689 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001281978.1 781348 R 419947 CDS YP_001281979.1 148660456 5215282 782027..782617 1 NC_009525.1 TetR family transcriptional regulator 782617 5215282 MRA_0690 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001281979.1 782027 D 419947 CDS YP_001281980.1 148660457 5215283 782866..783240 1 NC_009525.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 783240 rpsL 5215283 rpsL Mycobacterium tuberculosis H37Ra 30S ribosomal protein S12 YP_001281980.1 782866 D 419947 CDS YP_001281981.1 148660458 5215497 783240..783710 1 NC_009525.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 783710 rpsG 5215497 rpsG Mycobacterium tuberculosis H37Ra 30S ribosomal protein S7 YP_001281981.1 783240 D 419947 CDS YP_001281982.1 148660459 5215498 783791..785896 1 NC_009525.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 785896 fusA1 5215498 fusA1 Mycobacterium tuberculosis H37Ra elongation factor G YP_001281982.1 783791 D 419947 CDS YP_001281983.1 148660460 5215499 786127..787317 1 NC_009525.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 787317 tuf 5215499 tuf Mycobacterium tuberculosis H37Ra elongation factor Tu YP_001281983.1 786127 D 419947 CDS YP_001281984.1 148660461 5215500 787455..788252 1 NC_009525.1 hypothetical protein 788252 5215500 MRA_0695 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281984.1 787455 D 419947 CDS YP_001281985.1 148660462 5215501 788405..789232 1 NC_009525.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 789232 fabG 5215501 fabG Mycobacterium tuberculosis H37Ra 3-ketoacyl-ACP reductase YP_001281985.1 788405 D 419947 CDS YP_001281986.1 148660463 5215502 789246..790466 1 NC_009525.1 ferredoxin reductase 790466 5215502 MRA_0697 Mycobacterium tuberculosis H37Ra ferredoxin reductase YP_001281986.1 789246 D 419947 CDS YP_001281987.1 148660464 5215503 complement(790463..790717) 1 NC_009525.1 hypothetical protein 790717 5215503 MRA_0698 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281987.1 790463 R 419947 CDS YP_001281988.1 148660465 5215224 complement(791330..792379) 1 NC_009525.1 hypothetical protein 792379 5215224 MRA_0699 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281988.1 791330 R 419947 CDS YP_001281989.1 148660466 5215225 complement(792376..792972) 1 NC_009525.1 transcriptional regulatory protein 792972 5215225 MRA_0700 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001281989.1 792376 R 419947 CDS YP_001281990.1 148660467 5215226 793137..793466 1 NC_009525.1 hypothetical protein 793466 5215226 MRA_0700A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281990.1 793137 D 419947 CDS YP_001281991.1 148660468 5215227 793463..794638 1 NC_009525.1 coenzyme PQQ synthesis protein E 794638 pqqE 5215227 pqqE Mycobacterium tuberculosis H37Ra coenzyme PQQ synthesis protein E YP_001281991.1 793463 D 419947 CDS YP_001281992.1 148660469 5215228 794641..795831 1 NC_009525.1 FMN-dependent alpha-hydroxy acid dehydrogenase 795831 lldD1 5215228 lldD1 Mycobacterium tuberculosis H37Ra FMN-dependent alpha-hydroxy acid dehydrogenase YP_001281992.1 794641 D 419947 CDS YP_001281993.1 148660470 5215229 796021..796776 1 NC_009525.1 hypothetical protein 796776 5215229 MRA_0703 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281993.1 796021 D 419947 CDS YP_001281994.1 148660471 5215230 796825..798237 1 NC_009525.1 glycosyl transferase 798237 5215230 MRA_0704 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001281994.1 796825 D 419947 CDS YP_001281995.1 148660472 5213141 798239..799678 1 NC_009525.1 dehydrogenase 799678 5213141 MRA_0705 Mycobacterium tuberculosis H37Ra dehydrogenase YP_001281995.1 798239 D 419947 CDS YP_001281996.1 148660473 5213142 800139..800750 1 NC_009525.1 hypothetical protein 800750 5213142 MRA_0706 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281996.1 800139 D 419947 CDS YP_001281997.1 148660474 5213143 800935..801156 1 NC_009525.1 hypothetical protein 801156 5213143 MRA_0707 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001281997.1 800935 D 419947 CDS YP_001281998.1 148660475 5213144 801793..802098 1 NC_009525.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 802098 rpsJ 5213144 rpsJ Mycobacterium tuberculosis H37Ra 30S ribosomal protein S10 YP_001281998.1 801793 D 419947 CDS YP_001281999.1 148660476 5213145 802115..802768 1 NC_009525.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 802768 rplC 5213145 rplC Mycobacterium tuberculosis H37Ra 50S ribosomal protein L3 YP_001281999.1 802115 D 419947 CDS YP_001282000.1 148660477 5213146 802768..803439 1 NC_009525.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 803439 rplD 5213146 rplD Mycobacterium tuberculosis H37Ra 50S ribosomal protein L4 YP_001282000.1 802768 D 419947 CDS YP_001282001.1 148660478 5213147 803439..803741 1 NC_009525.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 803741 rplW 5213147 rplW Mycobacterium tuberculosis H37Ra 50S ribosomal protein L23 YP_001282001.1 803439 D 419947 CDS YP_001282002.1 148660479 5214585 803834..804676 1 NC_009525.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 804676 rplB 5214585 rplB Mycobacterium tuberculosis H37Ra 50S ribosomal protein L2 YP_001282002.1 803834 D 419947 CDS YP_001282003.1 148660480 5214586 804717..804998 1 NC_009525.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 804998 rpsS 5214586 rpsS Mycobacterium tuberculosis H37Ra 30S ribosomal protein S19 YP_001282003.1 804717 D 419947 CDS YP_001282004.1 148660481 5214587 804995..805588 1 NC_009525.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 805588 rplV 5214587 rplV Mycobacterium tuberculosis H37Ra 50S ribosomal protein L22 YP_001282004.1 804995 D 419947 CDS YP_001282005.1 148660482 5214588 805588..806412 1 NC_009525.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 806412 rpsC 5214588 rpsC Mycobacterium tuberculosis H37Ra 30S ribosomal protein S3 YP_001282005.1 805588 D 419947 CDS YP_001282006.1 148660483 5214589 806416..806832 1 NC_009525.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 806832 rplP 5214589 rplP Mycobacterium tuberculosis H37Ra 50S ribosomal protein L16 YP_001282006.1 806416 D 419947 CDS YP_001282007.1 148660484 5214590 806832..807065 1 NC_009525.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 807065 rpmC 5214590 rpmC Mycobacterium tuberculosis H37Ra 50S ribosomal protein L29 YP_001282007.1 806832 D 419947 CDS YP_001282008.1 148660485 5214591 807062..807472 1 NC_009525.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 807472 rpsQ 5214591 rpsQ Mycobacterium tuberculosis H37Ra 30S ribosomal protein S17 YP_001282008.1 807062 D 419947 CDS YP_001282009.1 148660486 5213652 807641..810004 1 NC_009525.1 arylsulfatase AtsA 810004 atsA 5213652 atsA Mycobacterium tuberculosis H37Ra arylsulfatase AtsA YP_001282009.1 807641 D 419947 CDS YP_001282010.1 148660487 5213653 810052..810951 1 NC_009525.1 hypothetical protein 810951 5213653 MRA_0720 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282010.1 810052 D 419947 CDS YP_001282011.1 148660488 5213654 811252..812193 1 NC_009525.1 transmembrane protein 812193 5213654 MRA_0721 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282011.1 811252 D 419947 CDS YP_001282012.1 148660489 5213655 812679..813047 1 NC_009525.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 813047 rplN 5213655 rplN Mycobacterium tuberculosis H37Ra 50S ribosomal protein L14 YP_001282012.1 812679 D 419947 CDS YP_001282013.1 148660490 5213656 813048..813365 1 NC_009525.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 813365 rplX 5213656 rplX Mycobacterium tuberculosis H37Ra 50S ribosomal protein L24 YP_001282013.1 813048 D 419947 CDS YP_001282014.1 148660491 5213657 813365..813928 1 NC_009525.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 813928 rplE 5213657 rplE Mycobacterium tuberculosis H37Ra 50S ribosomal protein L5 YP_001282014.1 813365 D 419947 CDS YP_001282015.1 148660492 5213658 813933..814118 1 NC_009525.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 814118 rpsN 5213658 rpsN Mycobacterium tuberculosis H37Ra 30S ribosomal protein S14 YP_001282015.1 813933 D 419947 CDS YP_001282016.1 148660493 5213194 814282..814680 1 NC_009525.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 814680 rpsH 5213194 rpsH Mycobacterium tuberculosis H37Ra 30S ribosomal protein S8 YP_001282016.1 814282 D 419947 CDS YP_001282017.1 148660494 5213195 814704..815243 1 NC_009525.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 815243 rplF 5213195 rplF Mycobacterium tuberculosis H37Ra 50S ribosomal protein L6 YP_001282017.1 814704 D 419947 CDS YP_001282018.1 148660495 5213196 815246..815614 1 NC_009525.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 815614 rplR 5213196 rplR Mycobacterium tuberculosis H37Ra 50S ribosomal protein L18 YP_001282018.1 815246 D 419947 CDS YP_001282019.1 148660496 5213197 815634..816296 1 NC_009525.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 816296 rpsE 5213197 rpsE Mycobacterium tuberculosis H37Ra 30S ribosomal protein S5 YP_001282019.1 815634 D 419947 CDS YP_001282020.1 148660497 5213198 816299..816496 1 NC_009525.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 816496 rpmD 5213198 rpmD Mycobacterium tuberculosis H37Ra 50S ribosomal protein L30 YP_001282020.1 816299 D 419947 CDS YP_001282021.1 148660498 5213199 816496..816936 1 NC_009525.1 late assembly protein; 50S ribosomal protein L15 816936 rplO 5213199 rplO Mycobacterium tuberculosis H37Ra 50S ribosomal protein L15 YP_001282021.1 816496 D 419947 CDS YP_001282022.1 148660499 5213200 816969..818840 1 NC_009525.1 signal peptide peptidase; endopeptidase iv; hypothetical protein 818840 sppA 5213200 sppA Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282022.1 816969 D 419947 CDS YP_001282023.1 148660500 5215292 complement(818845..819750) 1 NC_009525.1 hypothetical protein 819750 5215292 MRA_0733 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282023.1 818845 R 419947 CDS YP_001282024.1 148660501 5215293 complement(819843..820946) 1 NC_009525.1 hypothetical protein 820946 5215293 MRA_0734 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282024.1 819843 R 419947 CDS YP_001282025.1 148660502 5215294 complement(821149..821805) 1 NC_009525.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose-phosphate aldolase 821805 fucA 5215294 fucA Mycobacterium tuberculosis H37Ra L-fuculose-phosphate aldolase YP_001282025.1 821149 R 419947 CDS YP_001282026.1 148660503 5215295 complement(821802..822782) 1 NC_009525.1 2-hydroxyacid dehydrogenase 822782 serA2 5215295 serA2 Mycobacterium tuberculosis H37Ra 2-hydroxyacid dehydrogenase YP_001282026.1 821802 R 419947 CDS YP_001282027.1 148660504 5215296 822813..824159 1 NC_009525.1 D-xylulose kinase 824159 xylB 5215296 xylB Mycobacterium tuberculosis H37Ra D-xylulose kinase YP_001282027.1 822813 D 419947 CDS YP_001282028.1 148660505 5215297 824172..824900 1 NC_009525.1 hypothetical protein 824900 5215297 MRA_0738 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282028.1 824172 D 419947 CDS YP_001282029.1 148660506 5215298 complement(824989..825945) 1 NC_009525.1 hypothetical protein 825945 5215298 MRA_0739 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282029.1 824989 R 419947 CDS YP_001282030.1 148660507 5212239 826106..827431 1 NC_009525.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 827431 secY 5212239 secY Mycobacterium tuberculosis H37Ra preprotein translocase subunit SecY YP_001282030.1 826106 D 419947 CDS YP_001282031.1 148660508 5212240 827428..827973 1 NC_009525.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 827973 adk 5212240 adk Mycobacterium tuberculosis H37Ra adenylate kinase YP_001282031.1 827428 D 419947 CDS YP_001282032.1 148660509 5212241 827976..828776 1 NC_009525.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 828776 mapA 5212241 mapA Mycobacterium tuberculosis H37Ra methionine aminopeptidase YP_001282032.1 827976 D 419947 CDS YP_001282033.1 148660510 5212242 828849..829382 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and secreted or membrane proteins; RNA polymerase sigma factor SigL 829382 sigL 5212242 sigL Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigL YP_001282033.1 828849 D 419947 CDS YP_001282034.1 148660511 5212243 829446..830198 1 NC_009525.1 hypothetical protein 830198 5212243 MRA_0744 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282034.1 829446 D 419947 CDS YP_001282035.1 148660512 5212244 830253..830465 1 NC_009525.1 hypothetical protein 830465 5212244 MRA_0745 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282035.1 830253 D 419947 CDS YP_001282036.1 148660513 5212245 830513..831010 1 NC_009525.1 transcriptional regulatory protein 831010 5212245 MRA_0746 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282036.1 830513 D 419947 CDS YP_001282037.1 148660514 5212321 831368..831916 1 NC_009525.1 hypothetical protein 831916 5212321 MRA_0747 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282037.1 831368 D 419947 CDS YP_001282038.1 148660515 5212322 832161..832967 1 NC_009525.1 hypothetical protein 832967 5212322 MRA_0748 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282038.1 832161 D 419947 CDS YP_001282039.1 148660516 5212323 833082..833609 1 NC_009525.1 hypothetical protein 833609 5212323 MRA_0749 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282039.1 833082 D 419947 CDS YP_001282040.1 148660517 5212324 833840..834154 1 NC_009525.1 transposase 834154 5212324 MRA_0750 Mycobacterium tuberculosis H37Ra transposase YP_001282040.1 833840 D 419947 CDS YP_001282041.1 148660518 5212325 834296..834814 1 NC_009525.1 PE-PGRS family protein 834814 5212325 MRA_0751 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282041.1 834296 D 419947 CDS YP_001282042.1 148660519 5212326 complement(835192..835749) 1 NC_009525.1 hypothetical protein 835749 5212326 MRA_0752 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282042.1 835192 R 419947 CDS YP_001282043.1 148660520 5212327 complement(835746..836252) 1 NC_009525.1 transcriptional regulatory protein 836252 5212327 MRA_0753 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282043.1 835746 R 419947 CDS YP_001282044.1 148660521 5214275 837007..839358 1 NC_009525.1 PE-PGRS family protein 839358 5214275 MRA_0754 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282044.1 837007 D 419947 CDS YP_001282045.1 148660522 5214276 839757..842162 1 NC_009525.1 PE-PGRS family protein 842162 5214276 MRA_0755 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282045.1 839757 D 419947 CDS YP_001282046.1 148660523 5214277 842253..842510 1 NC_009525.1 hypothetical protein 842510 5214277 MRA_0756 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282046.1 842253 D 419947 CDS YP_001282047.1 148660524 5214278 842534..842962 1 NC_009525.1 hypothetical protein 842962 5214278 MRA_0757 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282047.1 842534 D 419947 CDS YP_001282048.1 148660525 5214279 complement(843043..843180) 1 NC_009525.1 hypothetical protein 843180 5214279 MRA_0758 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282048.1 843043 R 419947 CDS YP_001282049.1 148660526 5214280 843315..843584 1 NC_009525.1 hypothetical protein 843584 5214280 MRA_0759 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282049.1 843315 D 419947 CDS YP_001282050.1 148660527 5214281 complement(843653..844537) 1 NC_009525.1 3-hydroxyisobutyrate dehydrogenase 844537 mmsB 5214281 mmsB Mycobacterium tuberculosis H37Ra 3-hydroxyisobutyrate dehydrogenase YP_001282050.1 843653 R 419947 CDS YP_001282051.1 148660528 5214499 complement(844548..845720) 1 NC_009525.1 acyl-CoA dehydrogenase 845720 fadE9 5214499 fadE9 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001282051.1 844548 R 419947 CDS YP_001282052.1 148660529 5214500 complement(845727..847259) 1 NC_009525.1 methylmalonic acid semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase; MmsA 847259 mmsA 5214500 mmsA Mycobacterium tuberculosis H37Ra MmsA YP_001282052.1 845727 R 419947 CDS YP_001282053.1 148660530 5214501 847474..849219 1 NC_009525.1 PE-PGRS family protein 849219 5214501 MRA_0763 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282053.1 847474 D 419947 CDS YP_001282054.1 148660531 5214502 complement(849409..851346) 1 NC_009525.1 PPE family protein 851346 5214502 MRA_0764 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282054.1 849409 R 419947 CDS YP_001282055.1 148660532 5214503 complement(851648..851833) 1 NC_009525.1 ISMav2-like transposase 851833 5214503 MRA_0765 Mycobacterium tuberculosis H37Ra ISMav2-like transposase YP_001282055.1 851648 R 419947 CDS YP_001282056.1 148660533 5214505 complement(852047..852772) 1 NC_009525.1 hypothetical protein 852772 5214505 MRA_0766 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282056.1 852047 R 419947 CDS YP_001282057.1 148660534 5215306 852914..853657 1 NC_009525.1 two component system response transcriptional positive regulator PhoP 853657 phoP 5215306 phoP Mycobacterium tuberculosis H37Ra two component system response transcriptional positive regulator PhoP YP_001282057.1 852914 D 419947 CDS YP_001282058.1 148660535 5215307 853702..855159 1 NC_009525.1 two component system response sensor kinase membrane associated PhoR 855159 phoR 5215307 phoR Mycobacterium tuberculosis H37Ra two component system response sensor kinase membrane associated PhoR YP_001282058.1 853702 D 419947 CDS YP_001282059.1 148660536 5215308 complement(855131..855532) 1 NC_009525.1 hypothetical protein 855532 5215308 MRA_0769 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282059.1 855131 R 419947 CDS YP_001282060.1 148660537 5215309 complement(855573..855992) 1 NC_009525.1 hypothetical protein 855992 5215309 MRA_0770 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282060.1 855573 R 419947 CDS YP_001282061.1 148660538 5215310 complement(856005..857132) 1 NC_009525.1 zinc-containing alcohol dehydrogenase NAD dependent AdhB 857132 adhB 5215310 adhB Mycobacterium tuberculosis H37Ra zinc-containing alcohol dehydrogenase NAD dependent AdhB YP_001282061.1 856005 R 419947 CDS YP_001282062.1 148660539 5215311 complement(857231..857776) 1 NC_009525.1 hypothetical protein 857776 5215311 MRA_0771A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282062.1 857231 R 419947 CDS YP_001282063.1 148660540 5214074 complement(857779..857985) 1 NC_009525.1 ferredoxin 857985 5214074 MRA_0772 Mycobacterium tuberculosis H37Ra ferredoxin YP_001282063.1 857779 R 419947 CDS YP_001282064.1 148660541 5214075 complement(857988..859343) 1 NC_009525.1 cytochrome p450 51 cyp51 859343 cyp51 5214075 cyp51 Mycobacterium tuberculosis H37Ra cytochrome p450 51 cyp51 YP_001282064.1 857988 R 419947 CDS YP_001282065.1 148660542 5214076 complement(859343..860170) 1 NC_009525.1 short chain dehydrogenase 860170 5214076 MRA_0774 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001282065.1 859343 R 419947 CDS YP_001282066.1 148660543 5214077 complement(860170..861378) 1 NC_009525.1 cytochrome p450 123 CYP123 861378 cyp123 5214077 cyp123 Mycobacterium tuberculosis H37Ra cytochrome p450 123 CYP123 YP_001282066.1 860170 R 419947 CDS YP_001282067.1 148660544 5214078 complement(861375..862016) 1 NC_009525.1 hypothetical protein 862016 5214078 MRA_0776 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282067.1 861375 R 419947 CDS YP_001282068.1 148660545 5214079 862218..863687 1 NC_009525.1 NAD-dependent aldehyde dehydrogenase AldA 863687 aldA 5214079 aldA Mycobacterium tuberculosis H37Ra NAD-dependent aldehyde dehydrogenase AldA YP_001282068.1 862218 D 419947 CDS YP_001282069.1 148660546 5214080 863718..864464 1 NC_009525.1 short chain dehydrogenase 864464 5214080 MRA_0778 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001282069.1 863718 D 419947 CDS YP_001282070.1 148660547 5212649 864604..865449 1 NC_009525.1 dehydrogenase/reductase 865449 5212649 MRA_0779 Mycobacterium tuberculosis H37Ra dehydrogenase/reductase YP_001282070.1 864604 D 419947 CDS YP_001282071.1 148660548 5212650 865446..865880 1 NC_009525.1 4-carboxymuconolactone decarboxylase 865880 5212650 MRA_0780 Mycobacterium tuberculosis H37Ra 4-carboxymuconolactone decarboxylase YP_001282071.1 865446 D 419947 CDS YP_001282072.1 148660549 5212651 865892..867160 1 NC_009525.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 867160 purD 5212651 purD Mycobacterium tuberculosis H37Ra phosphoribosylamine--glycine ligase YP_001282072.1 865892 D 419947 CDS YP_001282073.1 148660550 5212652 complement(867157..868695) 1 NC_009525.1 bifunctional acylase GgtA 868695 ggtA 5212652 ggtA Mycobacterium tuberculosis H37Ra bifunctional acylase GgtA YP_001282073.1 867157 R 419947 CDS YP_001282074.1 148660551 5212653 complement(868746..869657) 1 NC_009525.1 hypothetical protein 869657 5212653 MRA_0783 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282074.1 868746 R 419947 CDS YP_001282075.1 148660552 5212654 869713..870336 1 NC_009525.1 hypothetical protein 870336 5212654 MRA_0784 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282075.1 869713 D 419947 CDS YP_001282076.1 148660553 5212655 complement(870290..871069) 1 NC_009525.1 hypothetical protein 871069 5212655 MRA_0785 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282076.1 870290 R 419947 CDS YP_001282077.1 148660554 5212908 871314..872732 1 NC_009525.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 872732 purB 5212908 purB Mycobacterium tuberculosis H37Ra adenylosuccinate lyase YP_001282077.1 871314 D 419947 CDS YP_001282078.1 148660555 5212909 872737..873981 1 NC_009525.1 cytochrome p450 126 CYP126 873981 cyp126 5212909 cyp126 Mycobacterium tuberculosis H37Ra cytochrome p450 126 CYP126 YP_001282078.1 872737 D 419947 CDS YP_001282079.1 148660556 5212910 complement(873978..874598) 1 NC_009525.1 transmembrane protein 874598 5212910 MRA_0788 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282079.1 873978 R 419947 CDS YP_001282080.1 148660557 5212911 874649..875542 1 NC_009525.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 875542 hemH 5212911 hemH Mycobacterium tuberculosis H37Ra phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001282080.1 874649 D 419947 CDS YP_001282081.1 148660558 5212912 875539..876249 1 NC_009525.1 protease II PtrBa 876249 ptrBa 5212912 ptrBa Mycobacterium tuberculosis H37Ra protease II PtrBa YP_001282081.1 875539 D 419947 CDS YP_001282082.1 148660559 5212913 876038..877696 1 NC_009525.1 protease II PtrBb 877696 ptrBb 5212913 ptrBb Mycobacterium tuberculosis H37Ra protease II PtrBb YP_001282082.1 876038 D 419947 CDS YP_001282083.1 148660560 5212914 complement(878124..879746) 1 NC_009525.1 multidrug resistance integral membrane efflux protein EmrB 879746 emrB 5212914 emrB Mycobacterium tuberculosis H37Ra multidrug resistance integral membrane efflux protein EmrB YP_001282083.1 878124 R 419947 CDS YP_001282084.1 148660561 5214909 879944..880630 1 NC_009525.1 hypothetical protein 880630 5214909 MRA_0793 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282084.1 879944 D 419947 CDS YP_001282085.1 148660562 5214910 880646..882346 1 NC_009525.1 proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 882346 5214910 MRA_0794 Mycobacterium tuberculosis H37Ra FAD-binding dehydrogenase YP_001282085.1 880646 D 419947 CDS YP_001282086.1 148660563 5214911 complement(882381..883019) 1 NC_009525.1 hypothetical protein 883019 5214911 MRA_0795 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282086.1 882381 R 419947 CDS YP_001282087.1 148660564 5214912 882765..883724 1 NC_009525.1 hypothetical protein 883724 5214912 MRA_0796 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282087.1 882765 D 419947 CDS YP_001282088.1 148660565 5214913 883830..884069 1 NC_009525.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS 884069 purS 5214913 purS Mycobacterium tuberculosis H37Ra phosphoribosylformylglycinamidine synthase subunit PurS YP_001282088.1 883830 D 419947 CDS YP_001282089.1 148660566 5214914 884066..884740 1 NC_009525.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 884740 purQ 5214914 purQ Mycobacterium tuberculosis H37Ra phosphoribosylformylglycinamidine synthase I YP_001282089.1 884066 D 419947 CDS YP_001282090.1 148660567 5214915 complement(884757..885356) 1 NC_009525.1 hypothetical protein 885356 5214915 MRA_0799 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282090.1 884757 R 419947 CDS YP_001282091.1 148660568 5214870 complement(885378..886106) 1 NC_009525.1 hypothetical protein 886106 5214870 MRA_0800 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282091.1 885378 R 419947 CDS YP_001282092.1 148660569 5214871 complement(886103..887146) 1 NC_009525.1 hypothetical protein 887146 5214871 MRA_0801 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282092.1 886103 R 419947 CDS YP_001282093.1 148660570 5214872 complement(887143..887952) 1 NC_009525.1 GntR family transcriptional regulator 887952 5214872 MRA_0802 Mycobacterium tuberculosis H37Ra GntR family transcriptional regulator YP_001282093.1 887143 R 419947 CDS YP_001282094.1 148660571 5214873 888025..888330 1 NC_009525.1 hypothetical protein 888330 5214873 MRA_0803 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282094.1 888025 D 419947 CDS YP_001282095.1 148660572 5214874 complement(888443..889942) 1 NC_009525.1 oxidoreductase 889942 5214874 MRA_0804 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001282095.1 888443 R 419947 CDS YP_001282096.1 148660573 5214875 890378..890704 1 NC_009525.1 IS6110 hypothetical protein 890704 5214875 MRA_0805 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001282096.1 890378 D 419947 CDS YP_001282097.1 148660574 5214876 890755..891639 1 NC_009525.1 IS6110 transposase 891639 5214876 MRA_0806 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001282097.1 890755 D 419947 CDS YP_001282098.1 148660575 5211806 891694..892788 1 NC_009525.1 IS1547 transposase 892788 5211806 MRA_0807 Mycobacterium tuberculosis H37Ra IS1547 transposase YP_001282098.1 891694 D 419947 CDS YP_001282099.1 148660576 5211807 complement(892778..893575) 1 NC_009525.1 antigen Cfp29 893575 cfp29 5211807 cfp29 Mycobacterium tuberculosis H37Ra antigen Cfp29 YP_001282099.1 892778 R 419947 CDS YP_001282100.1 148660577 5211808 complement(893572..894579) 1 NC_009525.1 hypothetical protein 894579 5211808 MRA_0809 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282100.1 893572 R 419947 CDS YP_001282101.1 148660578 5211809 894624..895925 1 NC_009525.1 catalyzes the removal of amino acids from the N termini of peptides; aminopeptidase 2 895925 pepC 5211809 pepC Mycobacterium tuberculosis H37Ra aminopeptidase 2 YP_001282101.1 894624 D 419947 CDS YP_001282102.1 148660579 5211810 895937..896284 1 NC_009525.1 hypothetical protein 896284 5211810 MRA_0811 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282102.1 895937 D 419947 CDS YP_001282103.1 148660580 5211811 complement(896278..896934) 1 NC_009525.1 hypothetical protein 896934 5211811 MRA_0812 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282103.1 896278 R 419947 CDS YP_001282104.1 148660581 5211812 897126..899390 1 NC_009525.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 899390 purL 5211812 purL Mycobacterium tuberculosis H37Ra phosphoribosylformylglycinamidine synthase II YP_001282104.1 897126 D 419947 CDS YP_001282105.1 148660582 5214311 899387..900016 1 NC_009525.1 hypothetical protein 900016 5214311 MRA_0814 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282105.1 899387 D 419947 CDS YP_001282106.1 148660583 5214312 900137..901093 1 NC_009525.1 hypothetical protein 901093 5214312 MRA_0815 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282106.1 900137 D 419947 CDS YP_001282107.1 148660584 5214313 complement(901038..902636) 1 NC_009525.1 UDP-glucose-4-epimerase 902636 cpsY 5214313 cpsY Mycobacterium tuberculosis H37Ra UDP-glucose-4-epimerase YP_001282107.1 901038 R 419947 CDS YP_001282108.1 148660585 5214314 902941..903330 1 NC_009525.1 hypothetical protein 903330 5214314 MRA_0817 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282108.1 902941 D 419947 CDS YP_001282109.1 148660586 5214315 903417..905000 1 NC_009525.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 905000 purF 5214315 purF Mycobacterium tuberculosis H37Ra amidophosphoribosyltransferase YP_001282109.1 903417 D 419947 CDS YP_001282110.1 148660587 5214316 905031..906125 1 NC_009525.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 906125 purM 5214316 purM Mycobacterium tuberculosis H37Ra phosphoribosylaminoimidazole synthetase YP_001282110.1 905031 D 419947 CDS YP_001282111.1 148660588 5214317 complement(906211..906393) 1 NC_009525.1 hypothetical protein 906393 5214317 MRA_0820 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282111.1 906211 R 419947 CDS YP_001282112.1 148660589 5214341 complement(906540..907646) 1 NC_009525.1 hypothetical protein 907646 5214341 MRA_0821 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282112.1 906540 R 419947 CDS YP_001282113.1 148660590 5214342 907729..908598 1 NC_009525.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 908598 5214342 MRA_0822 Mycobacterium tuberculosis H37Ra 4-amino-4-deoxychorismate lyase YP_001282113.1 907729 D 419947 CDS YP_001282114.1 148660591 5214343 complement(908644..909324) 1 NC_009525.1 hypothetical protein 909324 5214343 MRA_0823 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282114.1 908644 R 419947 CDS YP_001282115.1 148660592 5214344 complement(909487..909789) 1 NC_009525.1 hypothetical protein 909789 sseC1-1 5214344 sseC1-1 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282115.1 909487 R 419947 CDS YP_001282116.1 148660593 5214345 complement(909791..910624) 1 NC_009525.1 thiosulfate sulfurtransferase CysA2 910624 cysA2 5214345 cysA2 Mycobacterium tuberculosis H37Ra thiosulfate sulfurtransferase CysA2 YP_001282116.1 909791 R 419947 CDS YP_001282117.1 148660594 5214346 complement(910917..911339) 1 NC_009525.1 thioredoxin ThiX 911339 thiX 5214346 thiX Mycobacterium tuberculosis H37Ra thioredoxin ThiX YP_001282117.1 910917 R 419947 CDS YP_001282118.1 148660595 5214347 complement(911336..912148) 1 NC_009525.1 hypothetical protein 912148 5214347 MRA_0827 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282118.1 911336 R 419947 CDS YP_001282119.1 148660596 5214381 912278..913045 1 NC_009525.1 transcriptional regulator 913045 5214381 MRA_0828 Mycobacterium tuberculosis H37Ra transcriptional regulator YP_001282119.1 912278 D 419947 CDS YP_001282120.1 148660597 5214382 913042..913989 1 NC_009525.1 hypothetical protein 913989 5214382 MRA_0829 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282120.1 913042 D 419947 CDS YP_001282121.1 148660598 5214383 914032..914808 1 NC_009525.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 914808 phoT 5214383 phoT Mycobacterium tuberculosis H37Ra phosphate transporter ATP-binding protein YP_001282121.1 914032 D 419947 CDS YP_001282122.1 148660599 5214384 complement(914864..915505) 1 NC_009525.1 phosphate transport system regulatory protein 915505 phoY2 5214384 phoY2 Mycobacterium tuberculosis H37Ra phosphate transport system regulatory protein YP_001282122.1 914864 R 419947 CDS YP_001282123.1 148660600 5214385 complement(915563..917617) 1 NC_009525.1 hypothetical protein 917617 5214385 MRA_0832 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282123.1 915563 R 419947 CDS YP_001282124.1 148660601 5214386 complement(917783..918952) 1 NC_009525.1 NifR3/SMM1 family protein 918952 5214386 MRA_0833 Mycobacterium tuberculosis H37Ra NifR3/SMM1 family protein YP_001282124.1 917783 R 419947 CDS YP_001282125.1 148660602 5214387 complement(919040..920056) 1 NC_009525.1 fatty acid desaturase 920056 desA1 5214387 desA1 Mycobacterium tuberculosis H37Ra fatty acid desaturase YP_001282125.1 919040 R 419947 CDS YP_001282126.1 148660603 5212780 complement(920218..920859) 1 NC_009525.1 hypothetical protein 920859 5212780 MRA_0835 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282126.1 920218 R 419947 CDS YP_001282127.1 148660604 5212781 920940..921995 1 NC_009525.1 hypothetical protein 921995 5212781 MRA_0836 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282127.1 920940 D 419947 CDS YP_001282128.1 148660605 5212782 complement(922047..922439) 1 NC_009525.1 transcription regulator ArsR 922439 5212782 MRA_0837 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001282128.1 922047 R 419947 CDS YP_001282129.1 148660606 5212783 complement(922497..922919) 1 NC_009525.1 deaminase 922919 5212783 MRA_0838 Mycobacterium tuberculosis H37Ra deaminase YP_001282129.1 922497 R 419947 CDS YP_001282130.1 148660607 5212784 923276..924181 1 NC_009525.1 hypothetical protein 924181 5212784 MRA_0839 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282130.1 923276 D 419947 CDS YP_001282131.1 148660608 5212785 complement(924200..925015) 1 NC_009525.1 hypothetical protein 925015 5212785 MRA_0840 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282131.1 924200 R 419947 CDS YP_001282132.1 148660609 5214475 926257..926670 1 NC_009525.1 PE-PGRS family protein 926670 5214475 MRA_0841 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282132.1 926257 D 419947 CDS YP_001282133.1 148660610 5213614 926667..928916 1 NC_009525.1 PE-PGRS family protein 928916 5213614 MRA_0841A Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282133.1 926667 D 419947 CDS YP_001282134.1 148660611 5213615 complement(929143..931791) 1 NC_009525.1 PE-PGRS family protein 931791 5213615 MRA_0842 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282134.1 929143 R 419947 CDS YP_001282135.1 148660612 5213616 932259..932903 1 NC_009525.1 lipoprotein LpqQ 932903 lpqQ 5213616 lpqQ Mycobacterium tuberculosis H37Ra lipoprotein LpqQ YP_001282135.1 932259 D 419947 CDS YP_001282136.1 148660613 5213617 complement(933585..934238) 1 NC_009525.1 hypothetical protein 934238 5213617 MRA_0844 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282136.1 933585 R 419947 CDS YP_001282137.1 148660614 5213618 complement(934309..935337) 1 NC_009525.1 hypothetical protein 935337 5213618 MRA_0845 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282137.1 934309 R 419947 CDS YP_001282138.1 148660615 5213619 936026..936796 1 NC_009525.1 D-alanyl-D-alanine dipeptidase 936796 lpqR 5213619 lpqR Mycobacterium tuberculosis H37Ra D-alanyl-D-alanine dipeptidase YP_001282138.1 936026 D 419947 CDS YP_001282139.1 148660616 5213691 936883..937695 1 NC_009525.1 hypothetical protein 937695 5213691 MRA_0847 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282139.1 936883 D 419947 CDS YP_001282140.1 148660617 5213692 complement(937763..938623) 1 NC_009525.1 proline iminopeptidase 938623 pip 5213692 pip Mycobacterium tuberculosis H37Ra proline iminopeptidase YP_001282140.1 937763 R 419947 CDS YP_001282141.1 148660618 5213693 938899..939141 1 NC_009525.1 transmembrane protein 939141 5213693 MRA_0849 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282141.1 938899 D 419947 CDS YP_001282142.1 148660619 5213694 939418..940710 1 NC_009525.1 hypothetical protein 940710 5213694 MRA_0850 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282142.1 939418 D 419947 CDS YP_001282143.1 148660620 5213695 940694..941698 1 NC_009525.1 dehydrogenase E1 component 941698 5213695 MRA_0851 Mycobacterium tuberculosis H37Ra dehydrogenase E1 component YP_001282143.1 940694 D 419947 CDS YP_001282144.1 148660621 5213696 complement(941762..942412) 1 NC_009525.1 nitrate/nitrite response transcriptional regulatory protein NarL 942412 narL 5213696 narL Mycobacterium tuberculosis H37Ra nitrate/nitrite response transcriptional regulatory protein NarL YP_001282144.1 941762 R 419947 CDS YP_001282145.1 148660622 5213697 942496..943773 1 NC_009525.1 two component sensor kinase 943773 5213697 MRA_0853 Mycobacterium tuberculosis H37Ra two component sensor kinase YP_001282145.1 942496 D 419947 CDS YP_001282146.1 148660623 5212609 complement(943986..945500) 1 NC_009525.1 copper-binding protein 945500 5212609 MRA_0854 Mycobacterium tuberculosis H37Ra copper-binding protein YP_001282146.1 943986 R 419947 CDS YP_001282147.1 148660624 5212610 945649..946041 1 NC_009525.1 lipoprotein LpqS 946041 lpqS 5212610 lpqS Mycobacterium tuberculosis H37Ra lipoprotein LpqS YP_001282147.1 945649 D 419947 CDS YP_001282148.1 148660625 5212611 946244..947362 1 NC_009525.1 cysteine synthase A CysK2 947362 cysK2 5212611 cysK2 Mycobacterium tuberculosis H37Ra cysteine synthase A CysK2 YP_001282148.1 946244 D 419947 CDS YP_001282149.1 148660626 5212612 947362..948621 1 NC_009525.1 integral membrane transport protein 948621 5212612 MRA_0857 Mycobacterium tuberculosis H37Ra integral membrane transport protein YP_001282149.1 947362 D 419947 CDS YP_001282150.1 148660627 5212613 948618..948950 1 NC_009525.1 transposase 948950 5212613 MRA_0858 Mycobacterium tuberculosis H37Ra transposase YP_001282150.1 948618 D 419947 CDS YP_001282151.1 148660628 5212614 complement(948947..949774) 1 NC_009525.1 short chain dehydrogenase 949774 5212614 MRA_0859 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001282151.1 948947 R 419947 CDS YP_001282152.1 148660629 5212615 949865..950701 1 NC_009525.1 fatty-acid--CoA ligase 950701 fadD16 5212615 fadD16 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001282152.1 949865 D 419947 CDS YP_001282153.1 148660630 5214646 complement(950742..952424) 1 NC_009525.1 indolepyruvate decarboxylase 952424 pdc 5214646 pdc Mycobacterium tuberculosis H37Ra indolepyruvate decarboxylase YP_001282153.1 950742 R 419947 CDS YP_001282154.1 148660631 5214647 952489..952932 1 NC_009525.1 hypothetical protein 952932 5214647 MRA_0862 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282154.1 952489 D 419947 CDS YP_001282155.1 148660632 5214648 952938..954017 1 NC_009525.1 fatty-acid-CoA racemase 954017 far 5214648 far Mycobacterium tuberculosis H37Ra fatty-acid-CoA racemase YP_001282155.1 952938 D 419947 CDS YP_001282156.1 148660633 5214649 954131..954535 1 NC_009525.1 hypothetical protein 954535 5214649 MRA_0864 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282156.1 954131 D 419947 CDS YP_001282157.1 148660634 5214650 954563..955036 1 NC_009525.1 hypothetical protein 955036 5214650 MRA_0865 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282157.1 954563 D 419947 CDS YP_001282158.1 148660635 5214651 complement(955033..956226) 1 NC_009525.1 aminotransferase 956226 5214651 MRA_0866 Mycobacterium tuberculosis H37Ra aminotransferase YP_001282158.1 955033 R 419947 CDS YP_001282159.1 148660636 5214652 956383..957594 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 957594 fadA 5214652 fadA Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001282159.1 956383 D 419947 CDS YP_001282160.1 148660637 5211986 957599..959761 1 NC_009525.1 fatty oxidation complex subunit alpha 959761 fadB 5211986 fadB Mycobacterium tuberculosis H37Ra fatty oxidation complex subunit alpha YP_001282160.1 957599 D 419947 CDS YP_001282161.1 148660638 5211987 complement(959829..961457) 1 NC_009525.1 ATP-dependent DNA helicase 961457 ercc3 5211987 ercc3 Mycobacterium tuberculosis H37Ra ATP-dependent DNA helicase YP_001282161.1 959829 R 419947 CDS YP_001282162.1 148660639 5211988 complement(961648..963918) 1 NC_009525.1 hypothetical protein 963918 5211988 MRA_0870 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282162.1 961648 R 419947 CDS YP_001282163.1 148660640 5211989 963905..964186 1 NC_009525.1 hypothetical protein 964186 5211989 MRA_0870A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282163.1 963905 D 419947 CDS YP_001282164.1 148660641 5211990 964196..964699 1 NC_009525.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 964699 moaC 5211990 moaC Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein MoaC YP_001282164.1 964196 D 419947 CDS YP_001282165.1 148660642 5211991 964696..965178 1 NC_009525.1 molybdopterin biosynthesis Mog protein 965178 mog 5211991 mog Mycobacterium tuberculosis H37Ra molybdopterin biosynthesis Mog protein YP_001282165.1 964696 D 419947 CDS YP_001282166.1 148660643 5211992 965175..965600 1 NC_009525.1 molybdenum cofactor biosynthesis protein E2 965600 moaE2 5211992 moaE2 Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein E2 YP_001282166.1 965175 D 419947 CDS YP_001282167.1 148660644 5213979 complement(965618..966841) 1 NC_009525.1 resuscitation-promoting factor RpfA 966841 rpfA 5213979 rpfA Mycobacterium tuberculosis H37Ra resuscitation-promoting factor RpfA YP_001282167.1 965618 R 419947 CDS YP_001282168.1 148660645 5213980 complement(967289..967567) 1 NC_009525.1 molybdenum cofactor biosynthesis protein D2 967567 moaD2 5213980 moaD2 Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein D2 YP_001282168.1 967289 R 419947 CDS YP_001282169.1 148660646 5213981 complement(967571..968653) 1 NC_009525.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 968653 moaA 5213981 moaA Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein A YP_001282169.1 967571 R 419947 CDS YP_001282170.1 148660647 5213982 complement(968650..969039) 1 NC_009525.1 hypothetical protein 969039 5213982 MRA_0877 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282170.1 968650 R 419947 CDS YP_001282171.1 148660648 5213983 969204..969611 1 NC_009525.1 cold-shock domain-contain protein 969611 cspB 5213983 cspB Mycobacterium tuberculosis H37Ra cold-shock domain-contain protein YP_001282171.1 969204 D 419947 CDS YP_001282172.1 148660649 5213984 complement(969730..971550) 1 NC_009525.1 PE-PGRS family protein 971550 5213984 MRA_0879 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282172.1 969730 R 419947 CDS YP_001282173.1 148660650 5213985 971811..973763 1 NC_009525.1 acyl-CoA dehydrogenase 973763 fadE10 5213985 fadE10 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001282173.1 971811 D 419947 CDS YP_001282174.1 148660651 5213082 complement(973852..975012) 1 NC_009525.1 hypothetical protein 975012 5213082 MRA_0881 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282174.1 973852 R 419947 CDS YP_001282175.1 148660652 5213083 complement(975112..975600) 1 NC_009525.1 hypothetical protein 975600 5213083 MRA_0882 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282175.1 975112 R 419947 CDS YP_001282176.1 148660653 5213084 complement(975597..977243) 1 NC_009525.1 hypothetical protein 977243 5213084 MRA_0883 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282176.1 975597 R 419947 CDS YP_001282177.1 148660654 5213085 977381..978169 1 NC_009525.1 hypothetical protein 978169 5213085 MRA_0884 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282177.1 977381 D 419947 CDS YP_001282178.1 148660655 5213086 complement(978164..979510) 1 NC_009525.1 PPE family protein 979510 5213086 MRA_0885 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282178.1 978164 R 419947 CDS YP_001282179.1 148660656 5213087 complement(979788..980063) 1 NC_009525.1 transmembrane protein 980063 5213087 MRA_0886 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282179.1 979788 R 419947 CDS YP_001282180.1 148660657 5213088 980241..980672 1 NC_009525.1 MarR family transcriptional regulator 980672 5213088 MRA_0887 Mycobacterium tuberculosis H37Ra MarR family transcriptional regulator YP_001282180.1 980241 D 419947 CDS YP_001282181.1 148660658 5214716 980669..981535 1 NC_009525.1 rRNA methyltransferase 981535 5214716 MRA_0888 Mycobacterium tuberculosis H37Ra rRNA methyltransferase YP_001282181.1 980669 D 419947 CDS YP_001282182.1 148660659 5214717 981532..981816 1 NC_009525.1 transmembrane protein 981816 5214717 MRA_0889 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282182.1 981532 D 419947 CDS YP_001282183.1 148660660 5214718 complement(981813..982574) 1 NC_009525.1 hypothetical protein 982574 5214718 MRA_0890 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282183.1 981813 R 419947 CDS YP_001282184.1 148660661 5214719 complement(982731..983861) 1 NC_009525.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 983861 serC 5214719 serC Mycobacterium tuberculosis H37Ra phosphoserine aminotransferase YP_001282184.1 982731 R 419947 CDS YP_001282185.1 148660662 5214720 984069..985091 1 NC_009525.1 hypothetical protein 985091 5214720 MRA_0892 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282185.1 984069 D 419947 CDS YP_001282186.1 148660663 5214721 985110..986837 1 NC_009525.1 ferredoxin/ferredoxin--NADP reductase 986837 fprB 5214721 fprB Mycobacterium tuberculosis H37Ra ferredoxin/ferredoxin--NADP reductase YP_001282186.1 985110 D 419947 CDS YP_001282187.1 148660664 5214722 complement(986820..987278) 1 NC_009525.1 hypothetical protein 987278 5214722 MRA_0894 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282187.1 986820 R 419947 CDS YP_001282188.1 148660665 5213962 complement(988041..988229) 1 NC_009525.1 hypothetical protein 988229 5213962 MRA_0895 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282188.1 988041 R 419947 CDS YP_001282189.1 148660666 5213963 988540..990012 1 NC_009525.1 hypothetical protein 990012 5213963 MRA_0896 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282189.1 988540 D 419947 CDS YP_001282190.1 148660667 5213964 complement(990047..991168) 1 NC_009525.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; citrate synthase 2 991168 citA 5213964 citA Mycobacterium tuberculosis H37Ra citrate synthase 2 YP_001282190.1 990047 R 419947 CDS YP_001282191.1 148660668 5213965 complement(991255..993903) 1 NC_009525.1 LuxR family transcriptional regulator 993903 5213965 MRA_0898 Mycobacterium tuberculosis H37Ra LuxR family transcriptional regulator YP_001282191.1 991255 R 419947 CDS YP_001282192.1 148660669 5213966 complement(993905..994762) 1 NC_009525.1 transcriptional regulatory protein 994762 5213966 MRA_0899 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282192.1 993905 R 419947 CDS YP_001282193.1 148660670 5213967 995160..996647 1 NC_009525.1 monooxygenase 996647 5213967 MRA_0900 Mycobacterium tuberculosis H37Ra monooxygenase YP_001282193.1 995160 D 419947 CDS YP_001282194.1 148660671 5213968 complement(996625..997602) 1 NC_009525.1 hypothetical protein 997602 5213968 MRA_0901 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282194.1 996625 R 419947 CDS YP_001282195.1 148660672 5214703 997831..999012 1 NC_009525.1 MarR family transcriptional regulator 999012 5214703 MRA_0902 Mycobacterium tuberculosis H37Ra MarR family transcriptional regulator YP_001282195.1 997831 D 419947 CDS YP_001282196.1 148660673 5214704 999089..1000606 1 NC_009525.1 hypothetical protein 1000606 5214704 MRA_0903 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282196.1 999089 D 419947 CDS YP_001282197.1 148660674 5214705 1000779..1002074 1 NC_009525.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1002074 gltA 5214705 gltA Mycobacterium tuberculosis H37Ra type II citrate synthase YP_001282197.1 1000779 D 419947 CDS YP_001282198.1 148660675 5214706 complement(1002115..1003722) 1 NC_009525.1 oxidoreductase 1003722 5214706 MRA_0905 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001282198.1 1002115 R 419947 CDS YP_001282199.1 148660676 5214707 complement(1003748..1004011) 1 NC_009525.1 hypothetical protein 1004011 5214707 MRA_0905A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282199.1 1003748 R 419947 CDS YP_001282200.1 148660677 5214708 1004119..1005099 1 NC_009525.1 outer membrane protein A 1005099 ompA 5214708 ompA Mycobacterium tuberculosis H37Ra outer membrane protein A YP_001282200.1 1004119 D 419947 CDS YP_001282201.1 148660678 5214709 1005112..1005264 1 NC_009525.1 hypothetical protein 1005264 5214709 MRA_0907 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282201.1 1005112 D 419947 CDS YP_001282202.1 148660679 5214361 1005264..1005791 1 NC_009525.1 hypothetical protein 1005791 5214361 MRA_0908 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282202.1 1005264 D 419947 CDS YP_001282203.1 148660680 5214362 complement(1005808..1007148) 1 NC_009525.1 two component sensor histidine kinase PrrB 1007148 prrB 5214362 prrB Mycobacterium tuberculosis H37Ra two component sensor histidine kinase PrrB YP_001282203.1 1005808 R 419947 CDS YP_001282204.1 148660681 5214363 complement(1007159..1007869) 1 NC_009525.1 two component response transcriptional regulatory protein PrrA 1007869 prrA 5214363 prrA Mycobacterium tuberculosis H37Ra two component response transcriptional regulatory protein PrrA YP_001282204.1 1007159 R 419947 CDS YP_001282205.1 148660682 5214364 complement(1008000..1009487) 1 NC_009525.1 acetyl-CoA carboxylase carboxyl transferase subunit beta 1009487 accD3 5214364 accD3 Mycobacterium tuberculosis H37Ra acetyl-CoA carboxylase carboxyl transferase subunit beta YP_001282205.1 1008000 R 419947 CDS YP_001282206.1 148660683 5214365 1009514..1010245 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1010245 echA6 5214365 echA6 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001282206.1 1009514 D 419947 CDS YP_001282207.1 148660684 5214366 1010251..1011369 1 NC_009525.1 hypothetical protein 1011369 5214366 MRA_0913 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282207.1 1010251 D 419947 CDS YP_001282208.1 148660685 5214367 1011354..1013042 1 NC_009525.1 penicillin-binding protein 4 1013042 5214367 MRA_0914 Mycobacterium tuberculosis H37Ra penicillin-binding protein 4 YP_001282208.1 1011354 D 419947 CDS YP_001282209.1 148660686 5213668 1013039..1015432 1 NC_009525.1 metal cation transporting P-type ATPase CtpE 1015432 ctpE 5213668 ctpE Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpE YP_001282209.1 1013039 D 419947 CDS YP_001282210.1 148660687 5213669 1015989..1016168 1 NC_009525.1 hypothetical protein 1016168 5213669 MRA_0916 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282210.1 1015989 D 419947 CDS YP_001282211.1 148660688 5213670 1016174..1016608 1 NC_009525.1 hypothetical protein 1016608 5213670 MRA_0917 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282211.1 1016174 D 419947 CDS YP_001282212.1 148660689 5213671 1016706..1017479 1 NC_009525.1 hypothetical protein 1017479 5213671 MRA_0918 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282212.1 1016706 D 419947 CDS YP_001282213.1 148660690 5213672 1017544..1017993 1 NC_009525.1 transmembrane protein 1017993 5213672 MRA_0919 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282213.1 1017544 D 419947 CDS YP_001282214.1 148660691 5213673 complement(1018525..1020033) 1 NC_009525.1 dioxygenase 1020033 5213673 MRA_0920 Mycobacterium tuberculosis H37Ra dioxygenase YP_001282214.1 1018525 R 419947 CDS YP_001282215.1 148660692 5213674 complement(1020035..1021273) 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1021273 5213674 MRA_0921 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001282215.1 1020035 R 419947 CDS YP_001282216.1 148660693 5213450 complement(1021366..1022637) 1 NC_009525.1 PPE family protein 1022637 5213450 MRA_0922 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282216.1 1021366 R 419947 CDS YP_001282217.1 148660694 5213451 complement(1022652..1022951) 1 NC_009525.1 PE family protein 1022951 5213451 MRA_0923 Mycobacterium tuberculosis H37Ra PE family protein YP_001282217.1 1022652 R 419947 CDS YP_001282218.1 148660695 5213452 1023395..1025176 1 NC_009525.1 glycine betaine transport integral membrane protein BetP 1025176 betP 5213452 betP Mycobacterium tuberculosis H37Ra glycine betaine transport integral membrane protein BetP YP_001282218.1 1023395 D 419947 CDS YP_001282219.1 148660696 5213453 1025173..1025430 1 NC_009525.1 hypothetical protein 1025430 5213453 MRA_0925 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282219.1 1025173 D 419947 CDS YP_001282220.1 148660697 5213454 1025519..1025995 1 NC_009525.1 hypothetical protein 1025995 5213454 MRA_0926 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282220.1 1025519 D 419947 CDS YP_001282221.1 148660698 5213455 1025992..1026492 1 NC_009525.1 hypothetical protein 1026492 5213455 MRA_0927 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282221.1 1025992 D 419947 CDS YP_001282222.1 148660699 5213336 complement(1026805..1028124) 1 NC_009525.1 IS2606-like transposase 1028124 5213336 MRA_0928 Mycobacterium tuberculosis H37Ra IS2606-like transposase YP_001282222.1 1026805 R 419947 CDS YP_001282223.1 148660700 5213337 1028412..1028993 1 NC_009525.1 IS1535 resolvase 1028993 5213337 MRA_0929 Mycobacterium tuberculosis H37Ra IS1535 resolvase YP_001282223.1 1028412 D 419947 CDS YP_001282224.1 148660701 5213338 1028993..1030645 1 NC_009525.1 IS1535 transposase 1030645 5213338 MRA_0930 Mycobacterium tuberculosis H37Ra IS1535 transposase YP_001282224.1 1028993 D 419947 CDS YP_001282225.1 148660702 5213339 complement(1030821..1031885) 1 NC_009525.1 hypothetical protein 1031885 5213339 MRA_0931 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282225.1 1030821 R 419947 CDS YP_001282226.1 148660703 5213340 complement(1031886..1033172) 1 NC_009525.1 manganese transport protein MntH 1033172 mntH 5213340 mntH Mycobacterium tuberculosis H37Ra manganese transport protein MntH YP_001282226.1 1031886 R 419947 CDS YP_001282227.1 148660704 5213341 complement(1033204..1033941) 1 NC_009525.1 hypothetical protein 1033941 5213341 MRA_0933 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282227.1 1033204 R 419947 CDS YP_001282228.1 148660705 5215452 complement(1034018..1035094) 1 NC_009525.1 hypothetical protein 1035094 5215452 MRA_0934 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282228.1 1034018 R 419947 CDS YP_001282229.1 148660706 5215453 complement(1035148..1035939) 1 NC_009525.1 short chain dehydrogenase 1035939 5215453 MRA_0935 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001282229.1 1035148 R 419947 CDS YP_001282230.1 148660707 5215454 1036211..1037323 1 NC_009525.1 phosphate ABC transporter substrate-binding protein PstS3 1037323 pstS3 5215454 pstS3 Mycobacterium tuberculosis H37Ra phosphate ABC transporter substrate-binding protein PstS3 YP_001282230.1 1036211 D 419947 CDS YP_001282231.1 148660708 5215455 1037336..1038310 1 NC_009525.1 phosphate ABC transporter permease PstC2 1038310 pstC2 5215455 pstC2 Mycobacterium tuberculosis H37Ra phosphate ABC transporter permease PstC2 YP_001282231.1 1037336 D 419947 CDS YP_001282232.1 148660709 5215456 1038307..1039221 1 NC_009525.1 phosphate ABC transporter permease PstA1 1039221 pstA1 5215456 pstA1 Mycobacterium tuberculosis H37Ra phosphate ABC transporter permease PstA1 YP_001282232.1 1038307 D 419947 CDS YP_001282233.1 148660710 5215457 complement(1039228..1041222) 1 NC_009525.1 serine/threonine protein kinase 1041222 pknD 5215457 pknD Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001282233.1 1039228 R 419947 CDS YP_001282234.1 148660711 5215458 complement(1041244..1042356) 1 NC_009525.1 phosphate ABC transporter substrate-binding protein PstS2 1042356 pstS2 5215458 pstS2 Mycobacterium tuberculosis H37Ra phosphate ABC transporter substrate-binding protein PstS2 YP_001282234.1 1041244 R 419947 CDS YP_001282235.1 148660712 5212871 1042572..1043402 1 NC_009525.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 1043402 pstB 5212871 pstB Mycobacterium tuberculosis H37Ra phosphate ABC transporter ATP-binding protein YP_001282235.1 1042572 D 419947 CDS YP_001282236.1 148660713 5212872 1043423..1044547 1 NC_009525.1 phosphate ABC transporter substrate-binding protein PstS1 1044547 pstS1 5212872 pstS1 Mycobacterium tuberculosis H37Ra phosphate ABC transporter substrate-binding protein PstS1 YP_001282236.1 1043423 D 419947 CDS YP_001282237.1 148660714 5212873 1044607..1045623 1 NC_009525.1 phosphate ABC transporter permease PstC1 1045623 pstC1 5212873 pstC1 Mycobacterium tuberculosis H37Ra phosphate ABC transporter permease PstC1 YP_001282237.1 1044607 D 419947 CDS YP_001282238.1 148660715 5212874 1045625..1046530 1 NC_009525.1 phosphate ABC transporter permease PstA2 1046530 pstA2 5212874 pstA2 Mycobacterium tuberculosis H37Ra phosphate ABC transporter permease PstA2 YP_001282238.1 1045625 D 419947 CDS YP_001282239.1 148660716 5212875 complement(1046507..1047328) 1 NC_009525.1 hypothetical protein 1047328 5212875 MRA_0945 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282239.1 1046507 R 419947 CDS YP_001282240.1 148660717 5212876 1047444..1049723 1 NC_009525.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; ATP-dependent DNA ligase 1049723 5212876 MRA_0946 Mycobacterium tuberculosis H37Ra ATP-dependent DNA ligase YP_001282240.1 1047444 D 419947 CDS YP_001282241.1 148660718 5212877 1049720..1051654 1 NC_009525.1 fumarylacetoacetate hydrolase/metallo-beta-lactamase superfamily protein 1051654 5212877 MRA_0947 Mycobacterium tuberculosis H37Ra fumarylacetoacetate hydrolase/metallo-beta-lactamase superfamily protein YP_001282241.1 1049720 D 419947 CDS YP_001282242.1 148660719 5214059 complement(1051901..1052767) 1 NC_009525.1 FMNH2-dependent monooxygenase-related protein 1052767 5214059 MRA_0948 Mycobacterium tuberculosis H37Ra FMNH2-dependent monooxygenase-related protein YP_001282242.1 1051901 R 419947 CDS YP_001282243.1 148660720 5214060 complement(1052852..1053625) 1 NC_009525.1 hypothetical protein 1053625 5214060 MRA_0949 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282243.1 1052852 R 419947 CDS YP_001282244.1 148660721 5214061 1053668..1053946 1 NC_009525.1 hypothetical protein 1053946 5214061 MRA_0949A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282244.1 1053668 D 419947 CDS YP_001282245.1 148660722 5214062 complement(1054004..1055044) 1 NC_009525.1 hypothetical protein 1055044 5214062 MRA_0950 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282245.1 1054004 R 419947 CDS YP_001282246.1 148660723 5214063 1055073..1055549 1 NC_009525.1 formamidopyrimidine-DNA-glycosylase 1055549 5214063 MRA_0951 Mycobacterium tuberculosis H37Ra formamidopyrimidine-DNA-glycosylase YP_001282246.1 1055073 D 419947 CDS YP_001282247.1 148660724 5214064 1055555..1056316 1 NC_009525.1 short chain dehydrogenase 1056316 5214064 MRA_0952 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001282247.1 1055555 D 419947 CDS YP_001282248.1 148660725 5214065 complement(1056332..1057993) 1 NC_009525.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1057993 pgi 5214065 pgi Mycobacterium tuberculosis H37Ra glucose-6-phosphate isomerase YP_001282248.1 1056332 R 419947 CDS YP_001282249.1 148660726 5214195 complement(1058608..1058937) 1 NC_009525.1 hypothetical protein 1058937 5214195 MRA_0954 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282249.1 1058608 R 419947 CDS YP_001282250.1 148660727 5214196 complement(1058954..1059271) 1 NC_009525.1 hypothetical protein 1059271 5214196 MRA_0955 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282250.1 1058954 R 419947 CDS YP_001282251.1 148660728 5214197 1059568..1061883 1 NC_009525.1 ATP dependent DNA helicase UvrD1 1061883 uvrD1 5214197 uvrD1 Mycobacterium tuberculosis H37Ra ATP dependent DNA helicase UvrD1 YP_001282251.1 1059568 D 419947 CDS YP_001282252.1 148660729 5214198 complement(1061964..1062962) 1 NC_009525.1 hypothetical protein 1062962 5214198 MRA_0957 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282252.1 1061964 R 419947 CDS YP_001282253.1 148660730 5214199 1063272..1064435 1 NC_009525.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1064435 sucC 5214199 sucC Mycobacterium tuberculosis H37Ra succinyl-CoA synthetase subunit beta YP_001282253.1 1063272 D 419947 CDS YP_001282254.1 148660731 5214200 1064448..1065359 1 NC_009525.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1065359 sucD 5214200 sucD Mycobacterium tuberculosis H37Ra succinyl-CoA synthetase subunit alpha YP_001282254.1 1064448 D 419947 CDS YP_001282255.1 148660732 5214201 complement(1065422..1066270) 1 NC_009525.1 oxidoreductase 1066270 5214201 MRA_0960 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001282255.1 1065422 R 419947 CDS YP_001282256.1 148660733 5214514 1066435..1067346 1 NC_009525.1 transmembrane protein 1067346 5214514 MRA_0961 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282256.1 1066435 D 419947 CDS YP_001282257.1 148660734 5214515 1067386..1068753 1 NC_009525.1 integral membrane protein 1068753 5214515 MRA_0962 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001282257.1 1067386 D 419947 CDS YP_001282258.1 148660735 5214516 1068869..1069516 1 NC_009525.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 1069516 purN 5214516 purN Mycobacterium tuberculosis H37Ra phosphoribosylglycinamide formyltransferase YP_001282258.1 1068869 D 419947 CDS YP_001282259.1 148660736 5214517 1069513..1071084 1 NC_009525.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1071084 purH 5214517 purH Mycobacterium tuberculosis H37Ra bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001282259.1 1069513 D 419947 CDS YP_001282260.1 148660737 5214518 1071191..1072570 1 NC_009525.1 magnesium chelatase 1072570 5214518 MRA_0965 Mycobacterium tuberculosis H37Ra magnesium chelatase YP_001282260.1 1071191 D 419947 CDS YP_001282261.1 148660738 5214519 1072563..1074581 1 NC_009525.1 hypothetical protein 1074581 5214519 MRA_0966 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282261.1 1072563 D 419947 CDS YP_001282262.1 148660739 5214520 1074635..1074856 1 NC_009525.1 hypothetical protein 1074856 5214520 MRA_0967 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282262.1 1074635 D 419947 CDS YP_001282263.1 148660740 5215217 1074853..1075236 1 NC_009525.1 hypothetical protein 1075236 5215217 MRA_0968 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282263.1 1074853 D 419947 CDS YP_001282264.1 148660741 5215218 1075388..1075729 1 NC_009525.1 integral membrane protein 1075729 5215218 MRA_0969 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001282264.1 1075388 D 419947 CDS YP_001282265.1 148660742 5215219 complement(1075748..1076422) 1 NC_009525.1 lipoprotein LprP 1076422 lprP 5215219 lprP Mycobacterium tuberculosis H37Ra lipoprotein LprP YP_001282265.1 1075748 R 419947 CDS YP_001282266.1 148660743 5215220 complement(1076605..1077405) 1 NC_009525.1 hypothetical protein 1077405 5215220 MRA_0971 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282266.1 1076605 R 419947 CDS YP_001282267.1 148660744 5215221 complement(1077504..1077986) 1 NC_009525.1 hypothetical protein 1077986 5215221 MRA_0971A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282267.1 1077504 R 419947 CDS YP_001282268.1 148660745 5215222 complement(1078086..1078505) 1 NC_009525.1 hypothetical protein 1078505 5215222 MRA_0972 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282268.1 1078086 R 419947 CDS YP_001282269.1 148660746 5215223 complement(1078541..1079143) 1 NC_009525.1 hypothetical protein 1079143 5215223 MRA_0973 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282269.1 1078541 R 419947 CDS YP_001282270.1 148660747 5215299 1079283..1079642 1 NC_009525.1 hypothetical protein 1079642 5215299 MRA_0974 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282270.1 1079283 D 419947 CDS YP_001282271.1 148660748 5215300 1079699..1079995 1 NC_009525.1 hypothetical protein 1079995 5215300 MRA_0975 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282271.1 1079699 D 419947 CDS YP_001282272.1 148660749 5215301 1080051..1082363 1 NC_009525.1 metal cation transporting P-type ATPase CtpV 1082363 ctpV 5215301 ctpV Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpV YP_001282272.1 1080051 D 419947 CDS YP_001282273.1 148660750 5215302 1082360..1082992 1 NC_009525.1 integral membrane protein 1082992 5215302 MRA_0977 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001282273.1 1082360 D 419947 CDS YP_001282274.1 148660751 5215303 complement(1083083..1083892) 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1083892 echA7 5215303 echA7 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001282274.1 1083083 R 419947 CDS YP_001282275.1 148660752 5215304 complement(1083892..1085058) 1 NC_009525.1 acyl-CoA dehydrogenase 1085058 fadE12 5215304 fadE12 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001282275.1 1083892 R 419947 CDS YP_001282276.1 148660753 5215305 complement(1085055..1087058) 1 NC_009525.1 acetyl-/propionyl-coenzyme A carboxylase subunit alpha 1087058 accA2 5215305 accA2 Mycobacterium tuberculosis H37Ra acetyl-/propionyl-coenzyme A carboxylase subunit alpha YP_001282276.1 1085055 R 419947 CDS YP_001282277.1 148660754 5213729 complement(1087064..1088653) 1 NC_009525.1 propionyl-CoA carboxylase subunit beta 1088653 accD2 5213729 accD2 Mycobacterium tuberculosis H37Ra propionyl-CoA carboxylase subunit beta YP_001282277.1 1087064 R 419947 CDS YP_001282278.1 148660755 5213730 complement(1088656..1089804) 1 NC_009525.1 acyl-CoA dehydrogenase 1089804 fadE13 5213730 fadE13 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001282278.1 1088656 R 419947 CDS YP_001282279.1 148660756 5213731 complement(1089801..1091483) 1 NC_009525.1 hypothetical protein 1091483 5213731 MRA_0983 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282279.1 1089801 R 419947 CDS YP_001282280.1 148660757 5213732 1091681..1094452 1 NC_009525.1 PE-PGRS family protein 1094452 5213732 MRA_0984 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282280.1 1091681 D 419947 CDS YP_001282281.1 148660758 5213733 complement(1094669..1095664) 1 NC_009525.1 PE-PGRS family protein 1095664 5213733 MRA_0985 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282281.1 1094669 R 419947 CDS YP_001282282.1 148660759 5213734 complement(1095978..1096172) 1 NC_009525.1 hypothetical protein 1096172 5213734 MRA_0985A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282282.1 1095978 R 419947 CDS YP_001282283.1 148660760 5213735 1096194..1096367 1 NC_009525.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1096367 rpmF 5213735 rpmF Mycobacterium tuberculosis H37Ra 50S ribosomal protein L32 YP_001282283.1 1096194 D 419947 CDS YP_001282284.1 148660761 5212586 complement(1096386..1097759) 1 NC_009525.1 PE-PGRS family protein 1097759 5212586 MRA_0987 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282284.1 1096386 R 419947 CDS YP_001282285.1 148660762 5212587 1098124..1098816 1 NC_009525.1 two component response transcriptional regulatory protein MprA 1098816 mprA 5212587 mprA Mycobacterium tuberculosis H37Ra two component response transcriptional regulatory protein MprA YP_001282285.1 1098124 D 419947 CDS YP_001282286.1 148660763 5212588 1098816..1100330 1 NC_009525.1 two component sensor kinase MprB 1100330 mprB 5212588 mprB Mycobacterium tuberculosis H37Ra two component sensor kinase MprB YP_001282286.1 1098816 D 419947 CDS YP_001282287.1 148660764 5212589 1100374..1101768 1 NC_009525.1 serine protease PepD 1101768 pepD 5212589 pepD Mycobacterium tuberculosis H37Ra serine protease PepD YP_001282287.1 1100374 D 419947 CDS YP_001282288.1 148660765 5212590 1101768..1102313 1 NC_009525.1 pterin-4-alpha-carbinolamine dehydratase 1102313 moaB2 5212590 moaB2 Mycobacterium tuberculosis H37Ra pterin-4-alpha-carbinolamine dehydratase YP_001282288.1 1101768 D 419947 CDS YP_001282289.1 148660766 5212591 complement(1102333..1102788) 1 NC_009525.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 1102788 mscL 5212591 mscL Mycobacterium tuberculosis H37Ra large-conductance mechanosensitive channel YP_001282289.1 1102333 R 419947 CDS YP_001282290.1 148660767 5212592 1103111..1103857 1 NC_009525.1 adhesion component ABC transporter ATP-binding protein 1103857 5212592 MRA_0993 Mycobacterium tuberculosis H37Ra adhesion component ABC transporter ATP-binding protein YP_001282290.1 1103111 D 419947 CDS YP_001282291.1 148660768 5214485 1103850..1106417 1 NC_009525.1 adhesion component ABC transporter permease 1106417 5214485 MRA_0994 Mycobacterium tuberculosis H37Ra adhesion component ABC transporter permease YP_001282291.1 1103850 D 419947 CDS YP_001282292.1 148660769 5214486 1106424..1107584 1 NC_009525.1 hypothetical protein 1107584 5214486 MRA_0995 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282292.1 1106424 D 419947 CDS YP_001282293.1 148660770 5214487 complement(1107713..1108690) 1 NC_009525.1 polyprenyl synthetase 1108690 grcC2 5214487 grcC2 Mycobacterium tuberculosis H37Ra polyprenyl synthetase YP_001282293.1 1107713 R 419947 CDS YP_001282294.1 148660771 5214488 complement(1108751..1109407) 1 NC_009525.1 hypothetical protein 1109407 5214488 MRA_0997 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282294.1 1108751 R 419947 CDS YP_001282295.1 148660772 5214489 complement(1109480..1109812) 1 NC_009525.1 serine rich protein 1109812 5214489 MRA_0998 Mycobacterium tuberculosis H37Ra serine rich protein YP_001282295.1 1109480 R 419947 CDS YP_001282296.1 148660773 5214490 complement(1109886..1110479) 1 NC_009525.1 hypothetical protein 1110479 5214490 MRA_0999 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282296.1 1109886 R 419947 CDS YP_001282297.1 148660774 5214491 1110580..1111500 1 NC_009525.1 UTP-glucose-1-phosphate uridylyltransferase 1111500 galU 5214491 galU Mycobacterium tuberculosis H37Ra UTP-glucose-1-phosphate uridylyltransferase YP_001282297.1 1110580 D 419947 CDS YP_001282298.1 148660775 5212352 1111577..1112857 1 NC_009525.1 molybdopterin biosynthesis protein MoeA1 1112857 moeA1 5212352 moeA1 Mycobacterium tuberculosis H37Ra molybdopterin biosynthesis protein MoeA1 YP_001282298.1 1111577 D 419947 CDS YP_001282299.1 148660776 5212353 1112920..1113531 1 NC_009525.1 ribosomal-protein-alanine acetyltransferase RimJ 1113531 rimJ 5212353 rimJ Mycobacterium tuberculosis H37Ra ribosomal-protein-alanine acetyltransferase RimJ YP_001282299.1 1112920 D 419947 CDS YP_001282300.1 148660777 5212354 1113692..1114768 1 NC_009525.1 transmembrane protein 1114768 5212354 MRA_1003 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282300.1 1113692 D 419947 CDS YP_001282301.1 148660778 5212356 1115169..1115420 1 NC_009525.1 hypothetical protein 1115420 5212356 MRA_1004 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282301.1 1115169 D 419947 CDS YP_001282302.1 148660779 5212357 1115601..1116032 1 NC_009525.1 hypothetical protein 1116032 5212357 MRA_1006 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282302.1 1115601 D 419947 CDS YP_001282303.1 148660780 5215421 1116056..1117057 1 NC_009525.1 hypothetical protein 1117057 5215421 MRA_1007 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282303.1 1116056 D 419947 CDS YP_001282304.1 148660781 5215422 1117075..1117833 1 NC_009525.1 hypothetical protein 1117833 5215422 MRA_1008 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282304.1 1117075 D 419947 CDS YP_001282305.1 148660782 5215423 complement(1117839..1118456) 1 NC_009525.1 hypothetical protein 1118456 5215423 MRA_1009 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282305.1 1117839 R 419947 CDS YP_001282306.1 148660783 5215424 1118493..1119701 1 NC_009525.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 1119701 arcA 5215424 arcA Mycobacterium tuberculosis H37Ra arginine deiminase YP_001282306.1 1118493 D 419947 CDS YP_001282307.1 148660784 5215425 complement(1119736..1121247) 1 NC_009525.1 hypothetical protein 1121247 5215425 MRA_1011 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282307.1 1119736 R 419947 CDS YP_001282308.1 148660785 5215426 1121330..1122187 1 NC_009525.1 hypothetical protein 1122187 5215426 MRA_1012 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282308.1 1121330 D 419947 CDS YP_001282309.1 148660786 5215427 complement(1122197..1123495) 1 NC_009525.1 hypothetical protein 1123495 5215427 MRA_1013 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282309.1 1122197 R 419947 CDS YP_001282310.1 148660787 5212306 complement(1123530..1124906) 1 NC_009525.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase component I 1124906 pabB 5212306 pabB Mycobacterium tuberculosis H37Ra aminodeoxychorismate synthase component I YP_001282310.1 1123530 R 419947 CDS YP_001282311.1 148660788 5212307 1125022..1126725 1 NC_009525.1 hypothetical protein 1126725 5212307 MRA_1015 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282311.1 1125022 D 419947 CDS YP_001282312.1 148660789 5212308 complement(1126752..1128311) 1 NC_009525.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1128311 metG 5212308 metG Mycobacterium tuberculosis H37Ra methionyl-tRNA synthetase YP_001282312.1 1126752 R 419947 CDS YP_001282313.1 148660790 5212309 1128397..1129191 1 NC_009525.1 YjjV protein; deoxyribonuclease TatD 1129191 tatD 5212309 tatD Mycobacterium tuberculosis H37Ra deoxyribonuclease TatD YP_001282313.1 1128397 D 419947 CDS YP_001282314.1 148660791 5212310 1129399..1130487 1 NC_009525.1 resuscitation-promoting factor RpfB 1130487 rpfB 5212310 rpfB Mycobacterium tuberculosis H37Ra resuscitation-promoting factor RpfB YP_001282314.1 1129399 D 419947 CDS YP_001282315.1 148660792 5212311 1130460..1131413 1 NC_009525.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1131413 ksgA 5212311 ksgA Mycobacterium tuberculosis H37Ra dimethyladenosine transferase YP_001282315.1 1130460 D 419947 CDS YP_001282316.1 148660793 5212312 1131499..1132419 1 NC_009525.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1132419 ispE 5212312 ispE Mycobacterium tuberculosis H37Ra 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001282316.1 1131499 D 419947 CDS YP_001282317.1 148660794 5212956 1132436..1132729 1 NC_009525.1 hypothetical protein 1132729 5212956 MRA_1020A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282317.1 1132436 D 419947 CDS YP_001282318.1 148660795 5212957 1132933..1134567 1 NC_009525.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1134567 pks16 5212957 pks16 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--CoA ligase YP_001282318.1 1132933 D 419947 CDS YP_001282319.1 148660796 5212958 complement(1134641..1135216) 1 NC_009525.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1135216 pth 5212958 pth Mycobacterium tuberculosis H37Ra peptidyl-tRNA hydrolase YP_001282319.1 1134641 R 419947 CDS YP_001282320.1 148660797 5212959 complement(1135229..1135876) 1 NC_009525.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1135876 rplY 5212959 rplY Mycobacterium tuberculosis H37Ra 50S ribosomal protein L25 YP_001282320.1 1135229 R 419947 CDS YP_001282321.1 148660798 5212960 complement(1136093..1136773) 1 NC_009525.1 lipoprotein LpqT 1136773 lpqT 5212960 lpqT Mycobacterium tuberculosis H37Ra lipoprotein LpqT YP_001282321.1 1136093 R 419947 CDS YP_001282322.1 148660799 5212961 complement(1136809..1137789) 1 NC_009525.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1137789 prsA 5212961 prsA Mycobacterium tuberculosis H37Ra ribose-phosphate pyrophosphokinase YP_001282322.1 1136809 R 419947 CDS YP_001282323.1 148660800 5212962 complement(1137881..1139368) 1 NC_009525.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 1139368 glmU 5212962 glmU Mycobacterium tuberculosis H37Ra bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001282323.1 1137881 R 419947 CDS YP_001282324.1 148660801 5214369 1139623..1140216 1 NC_009525.1 TetR family transcriptional regulator 1140216 5214369 MRA_1027 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001282324.1 1139623 D 419947 CDS YP_001282325.1 148660802 5214370 1140275..1143979 1 NC_009525.1 transcription-repair coupling factor 1143979 mfd 5214370 mfd Mycobacterium tuberculosis H37Ra transcription-repair coupling factor YP_001282325.1 1140275 D 419947 CDS YP_001282326.1 148660803 5214371 1143979..1144956 1 NC_009525.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase 1144956 5214371 MRA_1029 Mycobacterium tuberculosis H37Ra nucleoside triphosphate pyrophosphohydrolase YP_001282326.1 1143979 D 419947 CDS YP_001282327.1 148660804 5214372 1145044..1145775 1 NC_009525.1 lipoprotein LpqU 1145775 lpqU 5214372 lpqU Mycobacterium tuberculosis H37Ra lipoprotein LpqU YP_001282327.1 1145044 D 419947 CDS YP_001282328.1 148660805 5214373 1145872..1147161 1 NC_009525.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1147161 eno 5214373 eno Mycobacterium tuberculosis H37Ra phosphopyruvate hydratase YP_001282328.1 1145872 D 419947 CDS YP_001282329.1 148660806 5213684 1147166..1147852 1 NC_009525.1 hypothetical protein 1147852 5213684 MRA_1032 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282329.1 1147166 D 419947 CDS YP_001282330.1 148660807 5213685 1147869..1148336 1 NC_009525.1 hypothetical protein 1148336 5213685 MRA_1033 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282330.1 1147869 D 419947 CDS YP_001282331.1 148660808 5213686 1148327..1149286 1 NC_009525.1 hypothetical protein 1149286 5213686 MRA_1034 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282331.1 1148327 D 419947 CDS YP_001282332.1 148660809 5213687 complement(1149735..1150415) 1 NC_009525.1 transcriptional regulatory protein KdpE 1150415 kdpE 5213687 kdpE Mycobacterium tuberculosis H37Ra transcriptional regulatory protein KdpE YP_001282332.1 1149735 R 419947 CDS YP_001282333.1 148660810 5213688 complement(1150412..1152994) 1 NC_009525.1 sensor histidine kinase KdpD 1152994 kdpD 5213688 kdpD Mycobacterium tuberculosis H37Ra sensor histidine kinase KdpD YP_001282333.1 1150412 R 419947 CDS YP_001282334.1 148660811 5213689 1153228..1153320 1 NC_009525.1 membrane protein KdpF 1153320 kdpF 5213689 kdpF Mycobacterium tuberculosis H37Ra membrane protein KdpF YP_001282334.1 1153228 D 419947 CDS YP_001282335.1 148660812 5213690 1153320..1155035 1 NC_009525.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 1155035 kdpA 5213690 kdpA Mycobacterium tuberculosis H37Ra potassium-transporting ATPase subunit A YP_001282335.1 1153320 D 419947 CDS YP_001282336.1 148660813 5211791 1155032..1157161 1 NC_009525.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 1157161 kdpB 5211791 kdpB Mycobacterium tuberculosis H37Ra potassium-transporting ATPase subunit B YP_001282336.1 1155032 D 419947 CDS YP_001282337.1 148660814 5211792 1157161..1157730 1 NC_009525.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 1157730 kdpC 5211792 kdpC Mycobacterium tuberculosis H37Ra potassium-transporting ATPase subunit C YP_001282337.1 1157161 D 419947 CDS YP_001282338.1 148660815 5211793 complement(1157734..1159263) 1 NC_009525.1 two component sensor histidine kinase TrcS 1159263 trcS 5211793 trcS Mycobacterium tuberculosis H37Ra two component sensor histidine kinase TrcS YP_001282338.1 1157734 R 419947 CDS YP_001282339.1 148660816 5211794 complement(1159271..1160044) 1 NC_009525.1 DNA-binding response regulator TrcR 1160044 trcR 5211794 trcR Mycobacterium tuberculosis H37Ra DNA-binding response regulator TrcR YP_001282339.1 1159271 R 419947 CDS YP_001282340.1 148660817 5211795 complement(1160226..1160615) 1 NC_009525.1 transposase 1160615 5211795 MRA_1042 Mycobacterium tuberculosis H37Ra transposase YP_001282340.1 1160226 R 419947 CDS YP_001282341.1 148660818 5211796 complement(1160683..1161369) 1 NC_009525.1 transposase 1161369 5211796 MRA_1043 Mycobacterium tuberculosis H37Ra transposase YP_001282341.1 1160683 R 419947 CDS YP_001282342.1 148660819 5211797 complement(1161403..1161741) 1 NC_009525.1 truncated IS1560 transposase 1161741 5211797 MRA_1044 Mycobacterium tuberculosis H37Ra truncated IS1560 transposase YP_001282342.1 1161403 R 419947 CDS YP_001282343.1 148660820 5214424 complement(1161852..1162136) 1 NC_009525.1 esat-6 like protein EsxV 1162136 esxV1 5214424 esxV1 Mycobacterium tuberculosis H37Ra esat-6 like protein EsxV YP_001282343.1 1161852 R 419947 CDS YP_001282344.1 148660821 5214425 complement(1162163..1162459) 1 NC_009525.1 esat-6 like protein EsxJ 1162459 esxJ 5214425 esxJ Mycobacterium tuberculosis H37Ra esat-6 like protein EsxJ YP_001282344.1 1162163 R 419947 CDS YP_001282345.1 148660822 5214426 complement(1162605..1163780) 1 NC_009525.1 PPE family protein 1163780 5214426 MRA_1047 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282345.1 1162605 R 419947 CDS YP_001282346.1 148660823 5214427 complement(1163857..1164684) 1 NC_009525.1 PE family protein 1164684 5214427 MRA_1048 Mycobacterium tuberculosis H37Ra PE family protein YP_001282346.1 1163857 R 419947 CDS YP_001282347.1 148660824 5214428 complement(1165472..1165780) 1 NC_009525.1 hypothetical protein 1165780 5214428 MRA_1049 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282347.1 1165472 R 419947 CDS YP_001282348.1 148660825 5214429 complement(1165880..1166743) 1 NC_009525.1 ISMt1 transposase B 1166743 5214429 MRA_1050 Mycobacterium tuberculosis H37Ra ISMt1 transposase B YP_001282348.1 1165880 R 419947 CDS YP_001282349.1 148660826 5214430 complement(1166400..1166807) 1 NC_009525.1 ISMt1 transposase A 1166807 5214430 MRA_1051 Mycobacterium tuberculosis H37Ra ISMt1 transposase A YP_001282349.1 1166400 R 419947 CDS YP_001282350.1 148660827 5212164 complement(1167089..1168114) 1 NC_009525.1 hypothetical protein 1168114 5212164 MRA_1052 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282350.1 1167089 R 419947 CDS YP_001282351.1 148660828 5212165 1168361..1168984 1 NC_009525.1 hypothetical protein 1168984 5212165 MRA_1053 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282351.1 1168361 D 419947 CDS YP_001282352.1 148660829 5212166 1168981..1169862 1 NC_009525.1 hypothetical protein 1169862 5212166 MRA_1054 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282352.1 1168981 D 419947 CDS YP_001282353.1 148660830 5212167 complement(1169944..1170537) 1 NC_009525.1 hypothetical protein 1170537 5212167 MRA_1055 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282353.1 1169944 R 419947 CDS YP_001282354.1 148660831 5212168 1170732..1171979 1 NC_009525.1 IS1081 transposase 1171979 5212168 MRA_1056 Mycobacterium tuberculosis H37Ra IS1081 transposase YP_001282354.1 1170732 D 419947 CDS YP_001282355.1 148660832 5212169 complement(1172347..1173462) 1 NC_009525.1 hypothetical protein 1173462 5212169 MRA_1057 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282355.1 1172347 R 419947 CDS YP_001282356.1 148660833 5212170 1173695..1174141 1 NC_009525.1 transcriptional repressor protein 1174141 5212170 MRA_1058 Mycobacterium tuberculosis H37Ra transcriptional repressor protein YP_001282356.1 1173695 D 419947 CDS YP_001282357.1 148660834 5212729 1174190..1175095 1 NC_009525.1 short-chain type dehydrogenase/reductase 1175095 5212729 MRA_1059 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001282357.1 1174190 D 419947 CDS YP_001282358.1 148660835 5212730 complement(1175254..1176009) 1 NC_009525.1 hypothetical protein 1176009 5212730 MRA_1060 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282358.1 1175254 R 419947 CDS YP_001282359.1 148660836 5212731 1177032..1177421 1 NC_009525.1 hypothetical protein 1177421 5212731 MRA_1061 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282359.1 1177032 D 419947 CDS YP_001282360.1 148660837 5212732 complement(1177320..1177595) 1 NC_009525.1 hypothetical protein 1177595 5212732 MRA_1062 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282360.1 1177320 R 419947 CDS YP_001282361.1 148660838 5212733 1178237..1178551 1 NC_009525.1 hypothetical protein 1178551 5212733 MRA_1063 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282361.1 1178237 D 419947 CDS YP_001282362.1 148660839 5212734 1178404..1178682 1 NC_009525.1 integrase 1178682 5212734 MRA_1064 Mycobacterium tuberculosis H37Ra integrase YP_001282362.1 1178404 D 419947 CDS YP_001282363.1 148660840 5214640 1178937..1179701 1 NC_009525.1 hypothetical protein 1179701 5214640 MRA_1065 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282363.1 1178937 D 419947 CDS YP_001282364.1 148660841 5214641 complement(1179913..1180059) 1 NC_009525.1 hypothetical protein 1180059 5214641 MRA_1066 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282364.1 1179913 R 419947 CDS YP_001282365.1 148660842 5214642 1180705..1181886 1 NC_009525.1 hypothetical protein 1181886 5214642 MRA_1067 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282365.1 1180705 D 419947 CDS YP_001282366.1 148660843 5214643 1181993..1183624 1 NC_009525.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1183624 fadD14 5214643 fadD14 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--CoA ligase YP_001282366.1 1181993 D 419947 CDS YP_001282367.1 148660844 5214644 1183700..1184764 1 NC_009525.1 hypothetical protein 1184764 5214644 MRA_1069 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282367.1 1183700 D 419947 CDS YP_001282368.1 148660845 5214645 1184817..1185290 1 NC_009525.1 hypothetical protein 1185290 5214645 MRA_1070 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282368.1 1184817 D 419947 CDS YP_001282369.1 148660846 5214447 1185324..1186187 1 NC_009525.1 hypothetical protein 1186187 5214447 MRA_1071 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282369.1 1185324 D 419947 CDS YP_001282370.1 148660847 5214448 1186192..1187049 1 NC_009525.1 hypothetical protein 1187049 5214448 MRA_1072 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282370.1 1186192 D 419947 CDS YP_001282371.1 148660848 5214449 complement(1187050..1188132) 1 NC_009525.1 hypothetical protein 1188132 5214449 MRA_1073 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282371.1 1187050 R 419947 CDS YP_001282372.1 148660849 5214450 complement(1188213..1188632) 1 NC_009525.1 lipoprotein LpqV 1188632 lpqV 5214450 lpqV Mycobacterium tuberculosis H37Ra lipoprotein LpqV YP_001282372.1 1188213 R 419947 CDS YP_001282373.1 148660850 5214451 1188744..1189310 1 NC_009525.1 hypothetical protein 1189310 5214451 MRA_1075 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282373.1 1188744 D 419947 CDS YP_001282374.1 148660851 5214452 1189307..1189702 1 NC_009525.1 hypothetical protein 1189702 5214452 MRA_1076 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282374.1 1189307 D 419947 CDS YP_001282375.1 148660852 5214453 complement(1189730..1191733) 1 NC_009525.1 PE-PGRS family protein 1191733 5214453 MRA_1077 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282375.1 1189730 R 419947 CDS YP_001282376.1 148660853 5214454 complement(1192066..1193457) 1 NC_009525.1 PE-PGRS family protein 1193457 5214454 MRA_1078 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282376.1 1192066 R 419947 CDS YP_001282377.1 148660854 5215119 complement(1193819..1195582) 1 NC_009525.1 hypothetical protein 1195582 5215119 MRA_1079 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282377.1 1193819 R 419947 CDS YP_001282378.1 148660855 5215120 complement(1195579..1196352) 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1196352 echA8 5215120 echA8 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001282378.1 1195579 R 419947 CDS YP_001282379.1 148660856 5215121 complement(1196364..1197401) 1 NC_009525.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 1197401 echA9 5215121 echA9 Mycobacterium tuberculosis H37Ra 3-hydroxyisobutyryl-CoA hydrolase YP_001282379.1 1196364 R 419947 CDS YP_001282380.1 148660857 5215122 1197588..1198424 1 NC_009525.1 transmembrane protein 1198424 5215122 MRA_1082 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282380.1 1197588 D 419947 CDS YP_001282381.1 148660858 5215123 1198540..1199391 1 NC_009525.1 hypothetical protein 1199391 5215123 MRA_1083 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282381.1 1198540 D 419947 CDS YP_001282382.1 148660859 5215124 complement(1199465..1200682) 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1200682 fadA3 5215124 fadA3 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001282382.1 1199465 R 419947 CDS YP_001282383.1 148660860 5215125 complement(1200735..1201679) 1 NC_009525.1 hypothetical protein 1201679 5215125 MRA_1085 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282383.1 1200735 R 419947 CDS YP_001282384.1 148660861 5211703 1202076..1202969 1 NC_009525.1 esterase 1202969 lipU 5211703 lipU Mycobacterium tuberculosis H37Ra esterase YP_001282384.1 1202076 D 419947 CDS YP_001282385.1 148660862 5211704 1203026..1204420 1 NC_009525.1 cysteine synthase/cystathionine beta-synthase 1204420 cbs 5211704 cbs Mycobacterium tuberculosis H37Ra cysteine synthase/cystathionine beta-synthase YP_001282385.1 1203026 D 419947 CDS YP_001282386.1 148660863 5211705 1204622..1205344 1 NC_009525.1 proline rich antigen-like protein 1205344 pra 5211705 pra Mycobacterium tuberculosis H37Ra proline rich antigen-like protein YP_001282386.1 1204622 D 419947 CDS YP_001282387.1 148660864 5211706 1205376..1206542 1 NC_009525.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 1206542 metB 5211706 metB Mycobacterium tuberculosis H37Ra cystathionine gamma-synthase YP_001282387.1 1205376 D 419947 CDS YP_001282388.1 148660865 5211707 complement(1206613..1207107) 1 NC_009525.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1207107 greA 5211707 greA Mycobacterium tuberculosis H37Ra transcription elongation factor GreA YP_001282388.1 1206613 R 419947 CDS YP_001282389.1 148660866 5211708 complement(1207293..1207727) 1 NC_009525.1 hypothetical protein 1207727 5211708 MRA_1091 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282389.1 1207293 R 419947 CDS YP_001282390.1 148660867 5211709 1207829..1208695 1 NC_009525.1 mycothiol conjugate amidase Mca 1208695 mca 5211709 mca Mycobacterium tuberculosis H37Ra mycothiol conjugate amidase Mca YP_001282390.1 1207829 D 419947 CDS YP_001282391.1 148660868 5213707 1208692..1208958 1 NC_009525.1 hypothetical protein 1208958 5213707 MRA_1093 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282391.1 1208692 D 419947 CDS YP_001282392.1 148660869 5213708 1208945..1210966 1 NC_009525.1 hypothetical protein 1210966 5213708 MRA_1094 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282392.1 1208945 D 419947 CDS YP_001282393.1 148660870 5213709 complement(1211065..1211793) 1 NC_009525.1 hemolysin-like protein 1211793 5213709 MRA_1095 Mycobacterium tuberculosis H37Ra hemolysin-like protein YP_001282393.1 1211065 R 419947 CDS YP_001282394.1 148660871 5213710 1211904..1212692 1 NC_009525.1 undecaprenyl diphosphate synthase 1212692 5213710 MRA_1096 Mycobacterium tuberculosis H37Ra undecaprenyl diphosphate synthase YP_001282394.1 1211904 D 419947 CDS YP_001282395.1 148660872 5213711 1212869..1215172 1 NC_009525.1 PE-PGRS family protein 1215172 5213711 MRA_1097 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282395.1 1212869 D 419947 CDS YP_001282396.1 148660873 5213712 1215349..1215669 1 NC_009525.1 hypothetical protein 1215669 5213712 MRA_1098 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282396.1 1215349 D 419947 CDS YP_001282397.1 148660874 5213713 1215804..1216256 1 NC_009525.1 PE family protein 1216256 5213713 MRA_1099 Mycobacterium tuberculosis H37Ra PE family protein YP_001282397.1 1215804 D 419947 CDS YP_001282398.1 148660875 5213015 1216826..1216930 1 NC_009525.1 cellulase CelA2a 1216930 celA2a 5213015 celA2a Mycobacterium tuberculosis H37Ra cellulase CelA2a YP_001282398.1 1216826 D 419947 CDS YP_001282399.1 148660876 5213016 1216908..1217363 1 NC_009525.1 cellulase CelA2b 1217363 celA2b 5213016 celA2b Mycobacterium tuberculosis H37Ra cellulase CelA2b YP_001282399.1 1216908 D 419947 CDS YP_001282400.1 148660877 5213017 1217778..1219517 1 NC_009525.1 PE-PGRS family protein 1219517 5213017 MRA_1102 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282400.1 1217778 D 419947 CDS YP_001282401.1 148660878 5213018 complement(1220558..1221496) 1 NC_009525.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1221496 coaA 5213018 coaA Mycobacterium tuberculosis H37Ra pantothenate kinase YP_001282401.1 1220558 R 419947 CDS YP_001282402.1 148660879 5213019 1221884..1223164 1 NC_009525.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1223164 glyA 5213019 glyA Mycobacterium tuberculosis H37Ra serine hydroxymethyltransferase YP_001282402.1 1221884 D 419947 CDS YP_001282403.1 148660880 5213020 1223269..1224096 1 NC_009525.1 acyl-(acyl-carrier-protein) desaturase 1224096 desA2 5213020 desA2 Mycobacterium tuberculosis H37Ra acyl-(acyl-carrier-protein) desaturase YP_001282403.1 1223269 D 419947 CDS YP_001282404.1 148660881 5213021 1224307..1225608 1 NC_009525.1 PhoH-like protein PhoH2 1225608 phoH2 5213021 phoH2 Mycobacterium tuberculosis H37Ra PhoH-like protein PhoH2 YP_001282404.1 1224307 D 419947 CDS YP_001282405.1 148660882 5212101 1225695..1226570 1 NC_009525.1 polysaccharide deacetylase 1226570 5212101 MRA_1107 Mycobacterium tuberculosis H37Ra polysaccharide deacetylase YP_001282405.1 1225695 D 419947 CDS YP_001282406.1 148660883 5212102 complement(1226573..1227454) 1 NC_009525.1 glycine and proline rich membrane protein 1227454 5212102 MRA_1108 Mycobacterium tuberculosis H37Ra glycine and proline rich membrane protein YP_001282406.1 1226573 R 419947 CDS YP_001282407.1 148660884 5212103 complement(1227451..1228875) 1 NC_009525.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1228875 fumC 5212103 fumC Mycobacterium tuberculosis H37Ra fumarate hydratase YP_001282407.1 1227451 R 419947 CDS YP_001282408.1 148660885 5212104 complement(1228906..1229892) 1 NC_009525.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 1229892 glpX 5212104 glpX Mycobacterium tuberculosis H37Ra fructose 1,6-bisphosphatase II YP_001282408.1 1228906 R 419947 CDS YP_001282409.1 148660886 5212105 1229993..1230694 1 NC_009525.1 hypothetical protein 1230694 5212105 MRA_1111 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282409.1 1229993 D 419947 CDS YP_001282410.1 148660887 5212106 complement(1230701..1231858) 1 NC_009525.1 hypothetical protein 1231858 5212106 MRA_1112 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282410.1 1230701 R 419947 CDS YP_001282411.1 148660888 5212107 complement(1231970..1232281) 1 NC_009525.1 hypothetical protein 1232281 5212107 MRA_1113 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282411.1 1231970 R 419947 CDS YP_001282412.1 148660889 5214975 complement(1232281..1232601) 1 NC_009525.1 hypothetical protein 1232601 5214975 MRA_1114 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282412.1 1232281 R 419947 CDS YP_001282413.1 148660890 5214976 1232611..1233300 1 NC_009525.1 para-nitrobenzyl esterase 1233300 5214976 MRA_1115 Mycobacterium tuberculosis H37Ra para-nitrobenzyl esterase YP_001282413.1 1232611 D 419947 CDS YP_001282414.1 148660891 5214977 1233621..1234136 1 NC_009525.1 para-nitrobenzyl esterase 1234136 5214977 MRA_1116 Mycobacterium tuberculosis H37Ra para-nitrobenzyl esterase YP_001282414.1 1233621 D 419947 CDS YP_001282415.1 148660892 5214978 complement(1234154..1235266) 1 NC_009525.1 3-beta hydroxysteroid dehydrogenase/isomerase 1235266 5214978 MRA_1117 Mycobacterium tuberculosis H37Ra 3-beta hydroxysteroid dehydrogenase/isomerase YP_001282415.1 1234154 R 419947 CDS YP_001282416.1 148660893 5214979 complement(1235276..1235533) 1 NC_009525.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1235533 xseB 5214979 xseB Mycobacterium tuberculosis H37Ra exodeoxyribonuclease VII small subunit YP_001282416.1 1235276 R 419947 CDS YP_001282417.1 148660894 5214980 complement(1235523..1236770) 1 NC_009525.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1236770 xseA 5214980 xseA Mycobacterium tuberculosis H37Ra exodeoxyribonuclease VII large subunit YP_001282417.1 1235523 R 419947 CDS YP_001282418.1 148660895 5214981 complement(1236767..1237405) 1 NC_009525.1 hypothetical protein 1237405 5214981 MRA_1120 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282418.1 1236767 R 419947 CDS YP_001282419.1 148660896 5215068 1237495..1238502 1 NC_009525.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1238502 ispH 5215068 ispH Mycobacterium tuberculosis H37Ra 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001282419.1 1237495 D 419947 CDS YP_001282420.1 148660897 5215069 complement(1238519..1239502) 1 NC_009525.1 hypothetical protein 1239502 5215069 MRA_1122 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282420.1 1238519 R 419947 CDS YP_001282421.1 148660898 5215070 1239565..1240638 1 NC_009525.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1240638 5215070 MRA_1123 Mycobacterium tuberculosis H37Ra GTP-dependent nucleic acid-binding protein EngD YP_001282421.1 1239565 D 419947 CDS YP_001282422.1 148660899 5215071 1240726..1240923 1 NC_009525.1 hypothetical protein 1240923 5215071 MRA_1123A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282422.1 1240726 D 419947 CDS YP_001282423.1 148660900 5215072 1240920..1241294 1 NC_009525.1 hypothetical protein 1241294 5215072 MRA_1124 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282423.1 1240920 D 419947 CDS YP_001282424.1 148660901 5215073 1241497..1242195 1 NC_009525.1 hypothetical protein 1242195 5215073 MRA_1125 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282424.1 1241497 D 419947 CDS YP_001282425.1 148660902 5215074 complement(1242425..1242700) 1 NC_009525.1 hypothetical protein 1242700 5215074 MRA_1126 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282425.1 1242425 R 419947 CDS YP_001282426.1 148660903 5215156 1242943..1243266 1 NC_009525.1 hypothetical protein 1243266 5215156 MRA_1127 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282426.1 1242943 D 419947 CDS YP_001282427.1 148660904 5215157 complement(1243281..1244141) 1 NC_009525.1 hypothetical protein 1244141 5215157 MRA_1128 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282427.1 1243281 R 419947 CDS YP_001282428.1 148660905 5215158 complement(1244174..1244323) 1 NC_009525.1 hypothetical protein 1244323 5215158 MRA_1128A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282428.1 1244174 R 419947 CDS YP_001282429.1 148660906 5215159 complement(1244320..1244814) 1 NC_009525.1 hypothetical protein 1244814 5215159 MRA_1129 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282429.1 1244320 R 419947 CDS YP_001282430.1 148660907 5215160 1245017..1246417 1 NC_009525.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1246417 zwf1 5215160 zwf1 Mycobacterium tuberculosis H37Ra glucose-6-phosphate 1-dehydrogenase YP_001282430.1 1245017 D 419947 CDS YP_001282431.1 148660908 5215161 1246439..1247461 1 NC_009525.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 1247461 gnd2 5215161 gnd2 Mycobacterium tuberculosis H37Ra 6-phosphogluconate dehydrogenase YP_001282431.1 1246439 D 419947 CDS YP_001282432.1 148660909 5215162 complement(1247454..1248362) 1 NC_009525.1 non-haem peroxidase; peroxidase BpoB 1248362 bpoB 5215162 bpoB Mycobacterium tuberculosis H37Ra peroxidase BpoB YP_001282432.1 1247454 R 419947 CDS YP_001282433.1 148660910 5215170 1248437..1249387 1 NC_009525.1 epoxide hydrolase EphC 1249387 ephC 5215170 ephC Mycobacterium tuberculosis H37Ra epoxide hydrolase EphC YP_001282433.1 1248437 D 419947 CDS YP_001282434.1 148660911 5215171 1249392..1250636 1 NC_009525.1 hypothetical protein 1250636 5215171 MRA_1134 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282434.1 1249392 D 419947 CDS YP_001282435.1 148660912 5215172 complement(1250640..1251245) 1 NC_009525.1 hypothetical protein 1251245 5215172 MRA_1135 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282435.1 1250640 R 419947 CDS YP_001282436.1 148660913 5215173 complement(1251242..1252714) 1 NC_009525.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 1252714 ppdK 5215173 ppdK Mycobacterium tuberculosis H37Ra pyruvate phosphate dikinase YP_001282436.1 1251242 R 419947 CDS YP_001282437.1 148660914 5215174 complement(1252927..1254282) 1 NC_009525.1 hypothetical protein 1254282 5215174 MRA_1137 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282437.1 1252927 R 419947 CDS YP_001282438.1 148660915 5215175 complement(1254384..1255844) 1 NC_009525.1 transcriptional regulator protein 1255844 5215175 MRA_1138 Mycobacterium tuberculosis H37Ra transcriptional regulator protein YP_001282438.1 1254384 R 419947 CDS YP_001282439.1 148660916 5215176 1255865..1257445 1 NC_009525.1 MmgE/PrpD family protein 1257445 5215176 MRA_1139 Mycobacterium tuberculosis H37Ra MmgE/PrpD family protein YP_001282439.1 1255865 D 419947 CDS YP_001282440.1 148660917 5215353 1257442..1258623 1 NC_009525.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 1258623 gltA1 5215353 gltA1 Mycobacterium tuberculosis H37Ra citrate synthase YP_001282440.1 1257442 D 419947 CDS YP_001282441.1 148660918 5215354 1258635..1260365 1 NC_009525.1 hypothetical protein 1260365 5215354 MRA_1141 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282441.1 1258635 D 419947 CDS YP_001282442.1 148660919 5215355 complement(1260377..1262656) 1 NC_009525.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1262656 metE 5215355 metE Mycobacterium tuberculosis H37Ra 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_001282442.1 1260377 R 419947 CDS YP_001282443.1 148660920 5215356 1263232..1263468 1 NC_009525.1 hypothetical protein 1263468 5215356 MRA_1143 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282443.1 1263232 D 419947 CDS YP_001282444.1 148660921 5215357 complement(1263582..1265438) 1 NC_009525.1 PPE family protein 1265438 5215357 MRA_1144 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282444.1 1263582 R 419947 CDS YP_001282445.1 148660922 5215358 1265624..1265866 1 NC_009525.1 acetyl-CoA acetyltransferase 1265866 5215358 MRA_1145 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001282445.1 1265624 D 419947 CDS YP_001282446.1 148660923 5215359 1265916..1266257 1 NC_009525.1 enoyl-CoA hydratase 1266257 5215359 MRA_1146 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001282446.1 1265916 D 419947 CDS YP_001282447.1 148660924 5211906 1266344..1266748 1 NC_009525.1 hypothetical protein 1266748 5211906 MRA_1147 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282447.1 1266344 D 419947 CDS YP_001282448.1 148660925 5211907 complement(1266782..1267798) 1 NC_009525.1 oxidoreductase 1267798 5211907 MRA_1148 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001282448.1 1266782 R 419947 CDS YP_001282449.1 148660926 5211908 complement(1267795..1268295) 1 NC_009525.1 hypothetical protein 1268295 5211908 MRA_1149 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282449.1 1267795 R 419947 CDS YP_001282450.1 148660927 5211909 1268657..1269505 1 NC_009525.1 hypothetical protein 1269505 5211909 MRA_1150 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282450.1 1268657 D 419947 CDS YP_001282451.1 148660928 5211910 complement(1269513..1270319) 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1270319 echA11 5211910 echA11 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001282451.1 1269513 R 419947 CDS YP_001282452.1 148660929 5211911 complement(1270462..1271268) 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1271268 echA10 5211911 echA10 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001282452.1 1270462 R 419947 CDS YP_001282453.1 148660930 5211912 1271372..1272454 1 NC_009525.1 alpha-methylacyl-CoA racemase Mcr 1272454 mcr 5211912 mcr Mycobacterium tuberculosis H37Ra alpha-methylacyl-CoA racemase Mcr YP_001282453.1 1271372 D 419947 CDS YP_001282454.1 148660931 5213714 1272466..1273218 1 NC_009525.1 short-chain type dehydrogenase/reductase 1273218 5213714 MRA_1154 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001282454.1 1272466 D 419947 CDS YP_001282455.1 148660932 5213715 1273733..1274644 1 NC_009525.1 transmembrane transport protein MmpL13a 1274644 mmpL13a 5213715 mmpL13a Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL13a YP_001282455.1 1273733 D 419947 CDS YP_001282456.1 148660933 5213716 1274578..1276077 1 NC_009525.1 transmembrane transport protein MmpL13b 1276077 mmpL13b 5213716 mmpL13b Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL13b YP_001282456.1 1274578 D 419947 CDS YP_001282457.1 148660934 5213717 1276210..1276860 1 NC_009525.1 hypothetical protein 1276860 5213717 MRA_1157 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282457.1 1276210 D 419947 CDS YP_001282458.1 148660935 5213718 complement(1277610..1279058) 1 NC_009525.1 hypothetical protein 1279058 5213718 MRA_1158 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282458.1 1277610 R 419947 CDS YP_001282459.1 148660936 5213719 1279203..1279610 1 NC_009525.1 ISMt1 transposase A 1279610 5213719 MRA_1159 Mycobacterium tuberculosis H37Ra ISMt1 transposase A YP_001282459.1 1279203 D 419947 CDS YP_001282460.1 148660937 5213720 1279267..1280130 1 NC_009525.1 ISMt1 transposase B 1280130 5213720 MRA_1160 Mycobacterium tuberculosis H37Ra ISMt1 transposase B YP_001282460.1 1279267 D 419947 CDS YP_001282461.1 148660938 5213955 complement(1280214..1280927) 1 NC_009525.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1280927 5213955 MRA_1161 Mycobacterium tuberculosis H37Ra NAD-dependent deacetylase YP_001282461.1 1280214 R 419947 CDS YP_001282462.1 148660939 5213956 1280965..1281330 1 NC_009525.1 GntR family transcriptional regulator 1281330 5213956 MRA_1162 Mycobacterium tuberculosis H37Ra GntR family transcriptional regulator YP_001282462.1 1280965 D 419947 CDS YP_001282463.1 148660940 5213957 complement(1281308..1282156) 1 NC_009525.1 O-methyltransferase 1282156 omt 5213957 omt Mycobacterium tuberculosis H37Ra O-methyltransferase YP_001282463.1 1281308 R 419947 CDS YP_001282464.1 148660941 5213958 complement(1282153..1282794) 1 NC_009525.1 hypothetical protein 1282794 5213958 MRA_1164 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282464.1 1282153 R 419947 CDS YP_001282465.1 148660942 5213959 1282739..1283182 1 NC_009525.1 hypothetical protein 1283182 5213959 MRA_1165 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282465.1 1282739 D 419947 CDS YP_001282466.1 148660943 5213960 1283616..1284203 1 NC_009525.1 hypothetical protein 1284203 5213960 MRA_1166 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282466.1 1283616 D 419947 CDS YP_001282467.1 148660944 5213961 complement(1284366..1285481) 1 NC_009525.1 hypothetical protein 1285481 5213961 MRA_1167 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282467.1 1284366 R 419947 CDS YP_001282468.1 148660945 5214334 complement(1285489..1286172) 1 NC_009525.1 hypothetical protein 1286172 5214334 MRA_1168 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282468.1 1285489 R 419947 CDS YP_001282469.1 148660946 5214335 1286302..1287597 1 NC_009525.1 involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis; mannosyltransferase 1287597 pimE 5214335 pimE Mycobacterium tuberculosis H37Ra mannosyltransferase YP_001282469.1 1286302 D 419947 CDS YP_001282470.1 148660947 5214336 complement(1287594..1287878) 1 NC_009525.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 1287878 phhB 5214336 phhB Mycobacterium tuberculosis H37Ra pterin-4-alpha-carbinolamine dehydratase YP_001282470.1 1287594 R 419947 CDS YP_001282471.1 148660948 5214337 1287905..1288330 1 NC_009525.1 mutator protein MutT2 1288330 mutT2 5214337 mutT2 Mycobacterium tuberculosis H37Ra mutator protein MutT2 YP_001282471.1 1287905 D 419947 CDS YP_001282472.1 148660949 5214338 1288638..1292336 1 NC_009525.1 respiratory nitrate reductase alpha chain NarG 1292336 narG 5214338 narG Mycobacterium tuberculosis H37Ra respiratory nitrate reductase alpha chain NarG YP_001282472.1 1288638 D 419947 CDS YP_001282473.1 148660950 5214339 1292375..1294051 1 NC_009525.1 respiratory nitrate reductase subunit beta NarH 1294051 narH 5214339 narH Mycobacterium tuberculosis H37Ra respiratory nitrate reductase subunit beta NarH YP_001282473.1 1292375 D 419947 CDS YP_001282474.1 148660951 5214340 1294108..1294713 1 NC_009525.1 respiratory nitrate reductase delta chain NarJ 1294713 narJ 5214340 narJ Mycobacterium tuberculosis H37Ra respiratory nitrate reductase delta chain NarJ YP_001282474.1 1294108 D 419947 CDS YP_001282475.1 148660952 5215566 1294716..1295456 1 NC_009525.1 respiratory nitrate reductase gamma chain NarI 1295456 narI 5215566 narI Mycobacterium tuberculosis H37Ra respiratory nitrate reductase gamma chain NarI YP_001282475.1 1294716 D 419947 CDS YP_001282476.1 148660953 5215567 1295478..1297364 1 NC_009525.1 GTP-binding elongation factor family protein 1297364 typA 5215567 typA Mycobacterium tuberculosis H37Ra GTP-binding elongation factor family protein YP_001282476.1 1295478 D 419947 CDS YP_001282477.1 148660954 5215568 1297462..1299369 1 NC_009525.1 lipoprotein LpqW 1299369 lpqW 5215568 lpqW Mycobacterium tuberculosis H37Ra lipoprotein LpqW YP_001282477.1 1297462 D 419947 CDS YP_001282478.1 148660955 5215569 complement(1299397..1300002) 1 NC_009525.1 transcriptional regulatory protein 1300002 5215569 MRA_1178 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282478.1 1299397 R 419947 CDS YP_001282479.1 148660956 5215570 complement(1300074..1301114) 1 NC_009525.1 PPE family protein 1301114 5215570 MRA_1179 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282479.1 1300074 R 419947 CDS YP_001282480.1 148660957 5215571 complement(1301132..1301434) 1 NC_009525.1 PE family protein 1301434 5215571 MRA_1180 Mycobacterium tuberculosis H37Ra PE family protein YP_001282480.1 1301132 R 419947 CDS YP_001282481.1 148660958 5215572 1301614..1302525 1 NC_009525.1 N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB 1302525 mshB 5215572 mshB Mycobacterium tuberculosis H37Ra N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB YP_001282481.1 1301614 D 419947 CDS YP_001282482.1 148660959 5211882 1302617..1303057 1 NC_009525.1 hypothetical protein 1303057 5211882 MRA_1182 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282482.1 1302617 D 419947 CDS YP_001282483.1 148660960 5211883 complement(1303065..1303991) 1 NC_009525.1 PE family protein 1303991 5211883 MRA_1183 Mycobacterium tuberculosis H37Ra PE family protein YP_001282483.1 1303065 R 419947 CDS YP_001282484.1 148660961 5211884 1304241..1306811 1 NC_009525.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; FO synthase 1306811 fbiC 5211884 fbiC Mycobacterium tuberculosis H37Ra FO synthase YP_001282484.1 1304241 D 419947 CDS YP_001282485.1 148660962 5211885 complement(1306979..1307311) 1 NC_009525.1 T-cell antigen 1307311 5211885 MRA_1185 Mycobacterium tuberculosis H37Ra T-cell antigen YP_001282485.1 1306979 R 419947 CDS YP_001282486.1 148660963 5211886 complement(1307512..1309536) 1 NC_009525.1 2,4-dienoyl-CoA reductase 1309536 fadH 5211886 fadH Mycobacterium tuberculosis H37Ra 2,4-dienoyl-CoA reductase YP_001282486.1 1307512 R 419947 CDS YP_001282487.1 148660964 5211887 complement(1309533..1310102) 1 NC_009525.1 hypothetical protein 1310102 5211887 MRA_1187 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282487.1 1309533 R 419947 CDS YP_001282488.1 148660965 5211888 1310315..1310641 1 NC_009525.1 ferredoxin FdxC 1310641 fdxC 5211888 fdxC Mycobacterium tuberculosis H37Ra ferredoxin FdxC YP_001282488.1 1310315 D 419947 CDS YP_001282489.1 148660966 5214037 1310674..1311762 1 NC_009525.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase 1311762 5214037 MRA_1189 Mycobacterium tuberculosis H37Ra N-succinyldiaminopimelate aminotransferase YP_001282489.1 1310674 D 419947 CDS YP_001282490.1 148660967 5214038 complement(1311790..1314609) 1 NC_009525.1 hypothetical protein 1314609 5214038 MRA_1190 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282490.1 1311790 R 419947 CDS YP_001282491.1 148660968 5214039 1315036..1321293 1 NC_009525.1 polyketide beta-ketoacyl synthase Pks3 1321293 pks3 5214039 pks3 Mycobacterium tuberculosis H37Ra polyketide beta-ketoacyl synthase Pks3 YP_001282491.1 1315036 D 419947 CDS YP_001282492.1 148660969 5214040 1321346..1322764 1 NC_009525.1 polyketide synthase associated protein PapA3 1322764 papA3 5214040 papA3 Mycobacterium tuberculosis H37Ra polyketide synthase associated protein PapA3 YP_001282492.1 1321346 D 419947 CDS YP_001282493.1 148660970 5214041 1322831..1325839 1 NC_009525.1 transmembrane transport protein MmpL10 1325839 mmpL10 5214041 mmpL10 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL10 YP_001282493.1 1322831 D 419947 CDS YP_001282494.1 148660971 5214042 complement(1325843..1326922) 1 NC_009525.1 hypothetical protein 1326922 5214042 MRA_1194 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282494.1 1325843 R 419947 CDS YP_001282495.1 148660972 5214043 complement(1327087..1328823) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1328823 fadD21 5214043 fadD21 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001282495.1 1327087 R 419947 CDS YP_001282496.1 148660973 5214318 complement(1329000..1330616) 1 NC_009525.1 hypothetical protein 1330616 5214318 MRA_1196 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282496.1 1329000 R 419947 CDS YP_001282497.1 148660974 5214319 1330701..1332332 1 NC_009525.1 delta-1-pyrroline-5-carboxylate dehydrogenase 1332332 rocA 5214319 rocA Mycobacterium tuberculosis H37Ra delta-1-pyrroline-5-carboxylate dehydrogenase YP_001282497.1 1330701 D 419947 CDS YP_001282498.1 148660975 5214320 1332332..1333321 1 NC_009525.1 proline dehydrogenase 1333321 5214320 MRA_1198 Mycobacterium tuberculosis H37Ra proline dehydrogenase YP_001282498.1 1332332 D 419947 CDS YP_001282499.1 148660976 5214321 1333403..1334275 1 NC_009525.1 member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigI 1334275 sigI 5214321 sigI Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigI YP_001282499.1 1333403 D 419947 CDS YP_001282500.1 148660977 5214322 1334291..1335169 1 NC_009525.1 hypothetical protein 1335169 5214322 MRA_1200 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282500.1 1334291 D 419947 CDS YP_001282501.1 148660978 5214323 1335242..1336156 1 NC_009525.1 hypothetical protein 1336156 5214323 MRA_1201 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282501.1 1335242 D 419947 CDS YP_001282502.1 148660979 5214324 1336238..1337065 1 NC_009525.1 hypothetical protein 1337065 5214324 MRA_1202 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282502.1 1336238 D 419947 CDS YP_001282503.1 148660980 5212665 1337105..1338526 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1338526 fadD36 5212665 fadD36 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001282503.1 1337105 D 419947 CDS YP_001282504.1 148660981 5212666 complement(1338559..1339824) 1 NC_009525.1 hypothetical protein 1339824 5212666 MRA_1204 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282504.1 1338559 R 419947 CDS YP_001282505.1 148660982 5212667 1340266..1340613 1 NC_009525.1 PE family protein 1340613 5212667 MRA_1205 Mycobacterium tuberculosis H37Ra PE family protein YP_001282505.1 1340266 D 419947 CDS YP_001282506.1 148660983 5212668 1340660..1341679 1 NC_009525.1 PPE family protein 1341679 5212668 MRA_1205A Mycobacterium tuberculosis H37Ra PPE family protein YP_001282506.1 1340660 D 419947 CDS YP_001282507.1 148660984 5212669 1341969..1342265 1 NC_009525.1 esat-6 like protein EsxK 1342265 esxK 5212669 esxK Mycobacterium tuberculosis H37Ra esat-6 like protein EsxK YP_001282507.1 1341969 D 419947 CDS YP_001282508.1 148660985 5212670 1342316..1342600 1 NC_009525.1 esat-6 like protein EsxL 1342600 esxL 5212670 esxL Mycobacterium tuberculosis H37Ra esat-6 like protein EsxL YP_001282508.1 1342316 D 419947 CDS YP_001282509.1 148660986 5212671 complement(1342668..1343915) 1 NC_009525.1 IS1081 transposase 1343915 5212671 MRA_1208 Mycobacterium tuberculosis H37Ra IS1081 transposase YP_001282509.1 1342668 R 419947 CDS YP_001282510.1 148660987 5215039 1344252..1345529 1 NC_009525.1 integral membrane transport protein 1345529 5215039 MRA_1209 Mycobacterium tuberculosis H37Ra integral membrane transport protein YP_001282510.1 1344252 D 419947 CDS YP_001282511.1 148660988 5215040 complement(1345526..1346479) 1 NC_009525.1 tetrahydrodipicolinate N-succinyltransferase 1346479 5215040 MRA_1210 Mycobacterium tuberculosis H37Ra tetrahydrodipicolinate N-succinyltransferase YP_001282511.1 1345526 R 419947 CDS YP_001282512.1 148660989 5215041 1346570..1347634 1 NC_009525.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 1347634 dapE 5215041 dapE Mycobacterium tuberculosis H37Ra succinyl-diaminopimelate desuccinylase YP_001282512.1 1346570 D 419947 CDS YP_001282513.1 148660990 5215042 complement(1347631..1348215) 1 NC_009525.1 hypothetical protein 1348215 5215042 MRA_1212 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282513.1 1347631 R 419947 CDS YP_001282514.1 148660991 5215043 complement(1348246..1349934) 1 NC_009525.1 hypothetical protein 1349934 5215043 MRA_1213 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282514.1 1348246 R 419947 CDS YP_001282515.1 148660992 5215044 1350029..1350592 1 NC_009525.1 hypothetical protein 1350592 5215044 MRA_1214 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282515.1 1350029 D 419947 CDS YP_001282516.1 148660993 5215045 1350642..1352435 1 NC_009525.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; long-chain-acyl-CoA synthetase 1352435 fadD6 5215045 fadD6 Mycobacterium tuberculosis H37Ra long-chain-acyl-CoA synthetase YP_001282516.1 1350642 D 419947 CDS YP_001282517.1 148660994 5215046 1352501..1353457 1 NC_009525.1 dihydropteroate synthase 1353457 folP2 5215046 folP2 Mycobacterium tuberculosis H37Ra dihydropteroate synthase YP_001282517.1 1352501 D 419947 CDS YP_001282518.1 148660995 5215185 1353454..1354428 1 NC_009525.1 glucosyl-3-phosphoglycerate synthase 1354428 5215185 MRA_1217 Mycobacterium tuberculosis H37Ra glucosyl-3-phosphoglycerate synthase YP_001282518.1 1353454 D 419947 CDS YP_001282519.1 148660996 5215186 1354467..1354835 1 NC_009525.1 hypothetical protein 1354835 5215186 MRA_1218 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282519.1 1354467 D 419947 CDS YP_001282520.1 148660997 5215187 1354832..1355446 1 NC_009525.1 DNA-3-methyladenine glycosidase I 1355446 tagA 5215187 tagA Mycobacterium tuberculosis H37Ra DNA-3-methyladenine glycosidase I YP_001282520.1 1354832 D 419947 CDS YP_001282521.1 148660998 5215188 1355553..1355780 1 NC_009525.1 hypothetical protein 1355780 5215188 MRA_1220 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282521.1 1355553 D 419947 CDS YP_001282522.1 148660999 5215189 complement(1355808..1356971) 1 NC_009525.1 glycogen synthase 1356971 5215189 MRA_1221 Mycobacterium tuberculosis H37Ra glycogen synthase YP_001282522.1 1355808 R 419947 CDS YP_001282523.1 148661000 5215190 1357146..1358360 1 NC_009525.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1358360 glgC 5215190 glgC Mycobacterium tuberculosis H37Ra glucose-1-phosphate adenylyltransferase YP_001282523.1 1357146 D 419947 CDS YP_001282524.1 148661001 5215191 complement(1358603..1358935) 1 NC_009525.1 PE family protein 1358935 5215191 MRA_1223 Mycobacterium tuberculosis H37Ra PE family protein YP_001282524.1 1358603 R 419947 CDS YP_001282525.1 148661002 5215192 complement(1359069..1360754) 1 NC_009525.1 hypothetical protein 1360754 5215192 MRA_1224 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282525.1 1359069 R 419947 CDS YP_001282526.1 148661003 5215377 complement(1360782..1361456) 1 NC_009525.1 integral membrane protein 1361456 5215377 MRA_1225 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001282526.1 1360782 R 419947 CDS YP_001282527.1 148661004 5215378 complement(1361465..1363111) 1 NC_009525.1 tetronasin ABC transporter permease 1363111 5215378 MRA_1226 Mycobacterium tuberculosis H37Ra tetronasin ABC transporter permease YP_001282527.1 1361465 R 419947 CDS YP_001282528.1 148661005 5215379 complement(1363108..1364043) 1 NC_009525.1 tetronasin ABC transporter ATP-binding protein 1364043 5215379 MRA_1227 Mycobacterium tuberculosis H37Ra tetronasin ABC transporter ATP-binding protein YP_001282528.1 1363108 R 419947 CDS YP_001282529.1 148661006 5215380 complement(1364033..1364671) 1 NC_009525.1 transcriptional regulatory protein 1364671 5215380 MRA_1228 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282529.1 1364033 R 419947 CDS YP_001282530.1 148661007 5215381 complement(1364813..1365460) 1 NC_009525.1 O-methyltransferase 1365460 5215381 MRA_1229 Mycobacterium tuberculosis H37Ra O-methyltransferase YP_001282530.1 1364813 R 419947 CDS YP_001282531.1 148661008 5215382 1365723..1366496 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence; RNA polymerase sigma factor SigE 1366496 sigE 5215382 sigE Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigE YP_001282531.1 1365723 D 419947 CDS YP_001282532.1 148661009 5215383 1366459..1367118 1 NC_009525.1 hypothetical protein 1367118 5215383 MRA_1231 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282532.1 1366459 D 419947 CDS YP_001282533.1 148661010 5215384 1367185..1368771 1 NC_009525.1 heat shock protein HtrA 1368771 htrA 5215384 htrA Mycobacterium tuberculosis H37Ra heat shock protein HtrA YP_001282533.1 1367185 D 419947 CDS YP_001282534.1 148661011 5211759 1368773..1369168 1 NC_009525.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 1369168 tatB 5211759 tatB Mycobacterium tuberculosis H37Ra sec-independent translocase YP_001282534.1 1368773 D 419947 CDS YP_001282535.1 148661012 5211760 complement(1369201..1370031) 1 NC_009525.1 hypothetical protein 1370031 5211760 MRA_1234 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282535.1 1369201 R 419947 CDS YP_001282536.1 148661013 5211761 complement(1370142..1371605) 1 NC_009525.1 transmembrane protein 1371605 5211761 MRA_1235 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282536.1 1370142 R 419947 CDS YP_001282537.1 148661014 5211762 complement(1371602..1372135) 1 NC_009525.1 transmembrane protein 1372135 5211762 MRA_1236 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282537.1 1371602 R 419947 CDS YP_001282538.1 148661015 5211763 1372230..1372787 1 NC_009525.1 lipoprotein LpqX 1372787 lpqX 5211763 lpqX Mycobacterium tuberculosis H37Ra lipoprotein LpqX YP_001282538.1 1372230 D 419947 CDS YP_001282539.1 148661016 5211764 complement(1373087..1374259) 1 NC_009525.1 MRP-related protein 1374259 mrp 5211764 mrp Mycobacterium tuberculosis H37Ra MRP-related protein YP_001282539.1 1373087 R 419947 CDS YP_001282540.1 148661017 5211765 complement(1374272..1375507) 1 NC_009525.1 hypothetical protein 1375507 5211765 MRA_1239 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282540.1 1374272 R 419947 CDS YP_001282541.1 148661018 5211766 complement(1375632..1376174) 1 NC_009525.1 hypothetical protein 1376174 5211766 MRA_1240 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282541.1 1375632 R 419947 CDS YP_001282542.1 148661019 5211913 complement(1376171..1377478) 1 NC_009525.1 hypothetical protein 1377478 5211913 MRA_1241 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282542.1 1376171 R 419947 CDS YP_001282543.1 148661020 5211914 complement(1377540..1378136) 1 NC_009525.1 hypothetical protein 1378136 5211914 MRA_1242 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282543.1 1377540 R 419947 CDS YP_001282544.1 148661021 5211915 1378286..1378813 1 NC_009525.1 transmembrane protein 1378813 5211915 MRA_1243 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282544.1 1378286 D 419947 CDS YP_001282545.1 148661022 5211916 1378834..1380240 1 NC_009525.1 sugar ABC transporter substrate-binding protein 1380240 lpqY 5211916 lpqY Mycobacterium tuberculosis H37Ra sugar ABC transporter substrate-binding protein YP_001282545.1 1378834 D 419947 CDS YP_001282546.1 148661023 5211917 1380237..1381160 1 NC_009525.1 sugar ABC transporter permease SugA 1381160 sugA 5211917 sugA Mycobacterium tuberculosis H37Ra sugar ABC transporter permease SugA YP_001282546.1 1380237 D 419947 CDS YP_001282547.1 148661024 5211918 1381165..1381989 1 NC_009525.1 sugar ABC transporter permease SugB 1381989 sugB 5211918 sugB Mycobacterium tuberculosis H37Ra sugar ABC transporter permease SugB YP_001282547.1 1381165 D 419947 CDS YP_001282548.1 148661025 5211919 1381994..1383175 1 NC_009525.1 sugar ABC transporter ATP-binding protein SugC 1383175 sugC 5211919 sugC Mycobacterium tuberculosis H37Ra sugar ABC transporter ATP-binding protein SugC YP_001282548.1 1381994 D 419947 CDS YP_001282549.1 148661026 5211920 complement(1383252..1384352) 1 NC_009525.1 CorA family transport protein 1384352 corA 5211920 corA Mycobacterium tuberculosis H37Ra CorA family transport protein YP_001282549.1 1383252 R 419947 CDS YP_001282550.1 148661027 5214226 1384523..1385512 1 NC_009525.1 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 1385512 mdh 5214226 mdh Mycobacterium tuberculosis H37Ra malate dehydrogenase YP_001282550.1 1384523 D 419947 CDS YP_001282551.1 148661028 5214227 1385588..1385848 1 NC_009525.1 hypothetical protein 1385848 5214227 MRA_1250 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282551.1 1385588 D 419947 CDS YP_001282552.1 148661029 5214228 1385845..1386276 1 NC_009525.1 hypothetical protein 1386276 5214228 MRA_1251 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282552.1 1385845 D 419947 CDS YP_001282553.1 148661030 5214229 complement(1386299..1387987) 1 NC_009525.1 PE-PGRS family protein 1387987 5214229 MRA_1252 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282553.1 1386299 R 419947 CDS YP_001282554.1 148661031 5214230 1388167..1389027 1 NC_009525.1 lipoprotein LpqZ 1389027 lpqZ 5214230 lpqZ Mycobacterium tuberculosis H37Ra lipoprotein LpqZ YP_001282554.1 1388167 D 419947 CDS YP_001282555.1 148661032 5214231 complement(1389108..1389938) 1 NC_009525.1 short-chain type dehydrogenase/reductase 1389938 5214231 MRA_1254 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001282555.1 1389108 R 419947 CDS YP_001282556.1 148661033 5214232 complement(1389995..1390288) 1 NC_009525.1 hypothetical protein 1390288 5214232 MRA_1255 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282556.1 1389995 R 419947 CDS YP_001282557.1 148661034 5214233 complement(1390285..1390554) 1 NC_009525.1 hypothetical protein 1390554 5214233 MRA_1255A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282557.1 1390285 R 419947 CDS YP_001282558.1 148661035 5214632 complement(1390667..1394311) 1 NC_009525.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase 1394311 kgd 5214632 kgd Mycobacterium tuberculosis H37Ra alpha-ketoglutarate decarboxylase YP_001282558.1 1390667 R 419947 CDS YP_001282559.1 148661036 5214633 complement(1394504..1395292) 1 NC_009525.1 hypothetical protein 1395292 5214633 MRA_1257 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282559.1 1394504 R 419947 CDS YP_001282560.1 148661037 5214634 1395489..1397228 1 NC_009525.1 drug-transport integral membrane protein 1397228 5214634 MRA_1258 Mycobacterium tuberculosis H37Ra drug-transport integral membrane protein YP_001282560.1 1395489 D 419947 CDS YP_001282561.1 148661038 5214635 complement(1397131..1400550) 1 NC_009525.1 hypothetical protein 1400550 5214635 MRA_1259 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282561.1 1397131 R 419947 CDS YP_001282562.1 148661039 5214636 complement(1400606..1401214) 1 NC_009525.1 lipoprotein LprE 1401214 lprE 5214636 lprE Mycobacterium tuberculosis H37Ra lipoprotein LprE YP_001282562.1 1400606 R 419947 CDS YP_001282563.1 148661040 5214637 1401280..1402971 1 NC_009525.1 ATP-dependent RNA helicase DeaD 1402971 deaD 5214637 deaD Mycobacterium tuberculosis H37Ra ATP-dependent RNA helicase DeaD YP_001282563.1 1401280 D 419947 CDS YP_001282564.1 148661041 5214638 1402968..1404119 1 NC_009525.1 acyltransferase 1404119 5214638 MRA_1262 Mycobacterium tuberculosis H37Ra acyltransferase YP_001282564.1 1402968 D 419947 CDS YP_001282565.1 148661042 5214639 complement(1404088..1404696) 1 NC_009525.1 transcriptional regulatory protein 1404696 5214639 MRA_1263 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282565.1 1404088 R 419947 CDS YP_001282566.1 148661043 5214624 complement(1404696..1405913) 1 NC_009525.1 cytochrome p450 130 CYP130 1405913 cyp130 5214624 cyp130 Mycobacterium tuberculosis H37Ra cytochrome p450 130 CYP130 YP_001282566.1 1404696 R 419947 CDS YP_001282567.1 148661044 5214625 complement(1406027..1407394) 1 NC_009525.1 oxidoreductase 1407394 5214625 MRA_1265 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001282567.1 1406027 R 419947 CDS YP_001282568.1 148661045 5214626 complement(1407391..1408650) 1 NC_009525.1 multidrug resistance efflux protein 1408650 5214626 MRA_1266 Mycobacterium tuberculosis H37Ra multidrug resistance efflux protein YP_001282568.1 1407391 R 419947 CDS YP_001282569.1 148661046 5214627 1408649..1409548 1 NC_009525.1 hypothetical protein 1409548 5214627 MRA_1267 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282569.1 1408649 D 419947 CDS YP_001282570.1 148661047 5214628 1409550..1410668 1 NC_009525.1 hypothetical protein 1410668 5214628 MRA_1268 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282570.1 1409550 D 419947 CDS YP_001282571.1 148661048 5214629 complement(1410794..1411243) 1 NC_009525.1 hypothetical protein 1411243 5214629 MRA_1269 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282571.1 1410794 R 419947 CDS YP_001282572.1 148661049 5214630 complement(1411248..1411682) 1 NC_009525.1 HIT family protein 1411682 5214630 MRA_1270 Mycobacterium tuberculosis H37Ra HIT family protein YP_001282572.1 1411248 R 419947 CDS YP_001282573.1 148661050 5214631 1411741..1413129 1 NC_009525.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1413129 amiB2 5214631 amiB2 Mycobacterium tuberculosis H37Ra amidase YP_001282573.1 1411741 D 419947 CDS YP_001282574.1 148661051 5213227 1413204..1414397 1 NC_009525.1 adenylate cyclase 1414397 5213227 MRA_1272 Mycobacterium tuberculosis H37Ra adenylate cyclase YP_001282574.1 1413204 D 419947 CDS YP_001282575.1 148661052 5213228 1414570..1415250 1 NC_009525.1 hypothetical protein 1415250 5213228 MRA_1273 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282575.1 1414570 D 419947 CDS YP_001282576.1 148661053 5213229 complement(1415270..1417150) 1 NC_009525.1 serine/threonine protein kinase 1417150 pknH 5213229 pknH Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001282576.1 1415270 R 419947 CDS YP_001282577.1 148661054 5213230 complement(1417491..1418657) 1 NC_009525.1 transcriptional regulatory protein EmbR 1418657 embR 5213230 embR Mycobacterium tuberculosis H37Ra transcriptional regulatory protein EmbR YP_001282577.1 1417491 R 419947 CDS YP_001282578.1 148661055 5213231 complement(1418968..1419666) 1 NC_009525.1 hypothetical protein 1419666 5213231 MRA_1276 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282578.1 1418968 R 419947 CDS YP_001282579.1 148661056 5213232 complement(1419889..1420263) 1 NC_009525.1 hypothetical protein 1420263 5213232 MRA_1277 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282579.1 1419889 R 419947 CDS YP_001282580.1 148661057 5213233 complement(1420324..1421058) 1 NC_009525.1 lipoprotein LprA 1421058 lprA 5213233 lprA Mycobacterium tuberculosis H37Ra lipoprotein LprA YP_001282580.1 1420324 R 419947 CDS YP_001282581.1 148661058 5213234 complement(1421271..1421612) 1 NC_009525.1 hypothetical protein 1421612 5213234 MRA_1279 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282581.1 1421271 R 419947 CDS YP_001282582.1 148661059 5211695 complement(1421720..1423615) 1 NC_009525.1 drugs ABC transporter ATP-binding protein 1423615 5211695 MRA_1280 Mycobacterium tuberculosis H37Ra drugs ABC transporter ATP-binding protein YP_001282582.1 1421720 R 419947 CDS YP_001282583.1 148661060 5211696 complement(1423612..1425360) 1 NC_009525.1 drugs ABC transporter ATP-binding protein 1425360 5211696 MRA_1281 Mycobacterium tuberculosis H37Ra drugs ABC transporter ATP-binding protein YP_001282583.1 1423612 R 419947 CDS YP_001282584.1 148661061 5211697 1425507..1426064 1 NC_009525.1 lipoprotein LprB 1426064 lprB 5211697 lprB Mycobacterium tuberculosis H37Ra lipoprotein LprB YP_001282584.1 1425507 D 419947 CDS YP_001282585.1 148661062 5211698 1426061..1426603 1 NC_009525.1 lipoprotein LprC 1426603 lprC 5211698 lprC Mycobacterium tuberculosis H37Ra lipoprotein LprC YP_001282585.1 1426061 D 419947 CDS YP_001282586.1 148661063 5211699 complement(1426748..1427224) 1 NC_009525.1 hypothetical protein 1427224 5211699 MRA_1284 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282586.1 1426748 R 419947 CDS YP_001282587.1 148661064 5211700 1427474..1428727 1 NC_009525.1 hypothetical protein 1428727 5211700 MRA_1285 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282587.1 1427474 D 419947 CDS YP_001282588.1 148661065 5211701 1428724..1431351 1 NC_009525.1 hypothetical protein 1431351 5211701 MRA_1286 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282588.1 1428724 D 419947 CDS YP_001282589.1 148661066 5211702 1431372..1432958 1 NC_009525.1 dehydrogenase FAD flavoprotein GMC oxidoreductase 1432958 5211702 MRA_1287 Mycobacterium tuberculosis H37Ra dehydrogenase FAD flavoprotein GMC oxidoreductase YP_001282589.1 1431372 D 419947 CDS YP_001282590.1 148661067 5211852 complement(1432975..1434750) 1 NC_009525.1 peptide ABC transporter substrate-binding protein 1434750 oppA 5211852 oppA Mycobacterium tuberculosis H37Ra peptide ABC transporter substrate-binding protein YP_001282590.1 1432975 R 419947 CDS YP_001282591.1 148661068 5211853 complement(1434743..1436581) 1 NC_009525.1 peptide ABC transporter ATP-binding protein 1436581 oppD 5211853 oppD Mycobacterium tuberculosis H37Ra peptide ABC transporter ATP-binding protein YP_001282591.1 1434743 R 419947 CDS YP_001282592.1 148661069 5211854 complement(1436578..1437453) 1 NC_009525.1 peptide ABC transporter permease 1437453 oppC 5211854 oppC Mycobacterium tuberculosis H37Ra peptide ABC transporter permease YP_001282592.1 1436578 R 419947 CDS YP_001282593.1 148661070 5211855 complement(1437450..1438427) 1 NC_009525.1 peptide ABC transporter permease 1438427 oppB 5211855 oppB Mycobacterium tuberculosis H37Ra peptide ABC transporter permease YP_001282593.1 1437450 R 419947 CDS YP_001282594.1 148661071 5211856 1438634..1439125 1 NC_009525.1 beta-carbonic anhydrase 1439125 5211856 MRA_1292 Mycobacterium tuberculosis H37Ra beta-carbonic anhydrase YP_001282594.1 1438634 D 419947 CDS YP_001282595.1 148661072 5211857 1439219..1440217 1 NC_009525.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 1440217 cysD 5211857 cysD Mycobacterium tuberculosis H37Ra sulfate adenylyltransferase subunit 2 YP_001282595.1 1439219 D 419947 CDS YP_001282596.1 148661073 5211858 1440217..1442061 1 NC_009525.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase 1442061 cysN 5211858 cysN Mycobacterium tuberculosis H37Ra bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase YP_001282596.1 1440217 D 419947 CDS YP_001282597.1 148661074 5211859 1442115..1442600 1 NC_009525.1 hypothetical protein 1442600 5211859 MRA_1295 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282597.1 1442115 D 419947 CDS YP_001282598.1 148661075 5212932 1442658..1444028 1 NC_009525.1 hypothetical protein 1444028 5212932 MRA_1296 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282598.1 1442658 D 419947 CDS YP_001282599.1 148661076 5212933 1444077..1444709 1 NC_009525.1 hypothetical protein 1444709 5212933 MRA_1297 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282599.1 1444077 D 419947 CDS YP_001282600.1 148661077 5212934 complement(1444792..1446357) 1 NC_009525.1 hypothetical protein 1446357 5212934 MRA_1298 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282600.1 1444792 R 419947 CDS YP_001282601.1 148661078 5212935 1446368..1446682 1 NC_009525.1 hypothetical protein 1446682 5212935 MRA_1298A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282601.1 1446368 D 419947 CDS YP_001282602.1 148661079 5212936 complement(1446809..1447144) 1 NC_009525.1 hypothetical protein 1447144 5212936 MRA_1299 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282602.1 1446809 R 419947 CDS YP_001282603.1 148661080 5212938 1447689..1449341 1 NC_009525.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1449341 argS 5212938 argS Mycobacterium tuberculosis H37Ra arginyl-tRNA synthetase YP_001282603.1 1447689 D 419947 CDS YP_001282604.1 148661081 5212123 1449338..1450681 1 NC_009525.1 diaminopimelate decarboxylase 1450681 lysA 5212123 lysA Mycobacterium tuberculosis H37Ra diaminopimelate decarboxylase YP_001282604.1 1449338 D 419947 CDS YP_001282605.1 148661082 5212124 1450685..1452010 1 NC_009525.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1452010 thrA 5212124 thrA Mycobacterium tuberculosis H37Ra homoserine dehydrogenase YP_001282605.1 1450685 D 419947 CDS YP_001282606.1 148661083 5212125 1452007..1453089 1 NC_009525.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1453089 thrC 5212125 thrC Mycobacterium tuberculosis H37Ra threonine synthase YP_001282606.1 1452007 D 419947 CDS YP_001282607.1 148661084 5212126 1453307..1454257 1 NC_009525.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1454257 thrB 5212126 thrB Mycobacterium tuberculosis H37Ra homoserine kinase YP_001282607.1 1453307 D 419947 CDS YP_001282608.1 148661085 5212127 1454514..1456322 1 NC_009525.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1456322 rho 5212127 rho Mycobacterium tuberculosis H37Ra transcription termination factor Rho YP_001282608.1 1454514 D 419947 CDS YP_001282609.1 148661086 5212128 1456473..1456715 1 NC_009525.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1456715 rpmE 5212128 rpmE Mycobacterium tuberculosis H37Ra 50S ribosomal protein L31 YP_001282609.1 1456473 D 419947 CDS YP_001282610.1 148661087 5212129 1456805..1457878 1 NC_009525.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1457878 prfA 5212129 prfA Mycobacterium tuberculosis H37Ra peptide chain release factor 1 YP_001282610.1 1456805 D 419947 CDS YP_001282611.1 148661088 5212130 1457875..1458852 1 NC_009525.1 hypothetical protein 1458852 hemK 5212130 hemK Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282611.1 1457875 D 419947 CDS YP_001282612.1 148661089 5214901 1458868..1459521 1 NC_009525.1 hypothetical protein 1459521 5214901 MRA_1309 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282612.1 1458868 D 419947 CDS YP_001282613.1 148661090 5214902 1459605..1460819 1 NC_009525.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1460819 rfe 5214902 rfe Mycobacterium tuberculosis H37Ra undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_001282613.1 1459605 D 419947 CDS YP_001282614.1 148661091 5214903 1461076..1461561 1 NC_009525.1 hypothetical protein 1461561 5214903 MRA_1311 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282614.1 1461076 D 419947 CDS YP_001282615.1 148661092 5214904 1461554..1462306 1 NC_009525.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 1462306 atpB 5214904 atpB Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit A YP_001282615.1 1461554 D 419947 CDS YP_001282616.1 148661093 5214905 1462355..1462600 1 NC_009525.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 1462600 atpE 5214905 atpE Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit C YP_001282616.1 1462355 D 419947 CDS YP_001282617.1 148661094 5214906 1462631..1463146 1 NC_009525.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 1463146 atpF 5214906 atpF Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit B YP_001282617.1 1462631 D 419947 CDS YP_001282618.1 148661095 5214907 1463153..1464493 1 NC_009525.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 1464493 atpH 5214907 atpH Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit delta YP_001282618.1 1463153 D 419947 CDS YP_001282619.1 148661096 5214908 1464538..1466187 1 NC_009525.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1466187 atpA 5214908 atpA Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit alpha YP_001282619.1 1464538 D 419947 CDS YP_001282620.1 148661097 5212193 1466194..1467111 1 NC_009525.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1467111 atpG 5212193 atpG Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit gamma YP_001282620.1 1466194 D 419947 CDS YP_001282621.1 148661098 5212194 1467151..1468611 1 NC_009525.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1468611 atpD 5212194 atpD Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit beta YP_001282621.1 1467151 D 419947 CDS YP_001282622.1 148661099 5212195 1468625..1468990 1 NC_009525.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 1468990 atpC 5212195 atpC Mycobacterium tuberculosis H37Ra ATP synthase F0F1 subunit epsilon YP_001282622.1 1468625 D 419947 CDS YP_001282623.1 148661100 5212196 1468998..1469441 1 NC_009525.1 hypothetical protein 1469441 5212196 MRA_1320 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282623.1 1468998 D 419947 CDS YP_001282624.1 148661101 5212197 complement(1469481..1470815) 1 NC_009525.1 transposase 1470815 5212197 MRA_1321 Mycobacterium tuberculosis H37Ra transposase YP_001282624.1 1469481 R 419947 CDS YP_001282625.1 148661102 5212198 complement(1470981..1471562) 1 NC_009525.1 hypothetical protein 1471562 5212198 MRA_1322 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282625.1 1470981 R 419947 CDS YP_001282626.1 148661103 5212199 1471631..1472887 1 NC_009525.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1472887 murA 5212199 murA Mycobacterium tuberculosis H37Ra UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001282626.1 1471631 D 419947 CDS YP_001282627.1 148661104 5214612 complement(1478444..1478941) 1 NC_009525.1 methylated-DNA--protein-cysteine methyltransferase 1478941 ogt 5214612 ogt Mycobacterium tuberculosis H37Ra methylated-DNA--protein-cysteine methyltransferase YP_001282627.1 1478444 R 419947 CDS YP_001282628.1 148661105 5214613 complement(1478938..1480428) 1 NC_009525.1 ada regulatory protein AlkA 1480428 alkA 5214613 alkA Mycobacterium tuberculosis H37Ra ada regulatory protein AlkA YP_001282628.1 1478938 R 419947 CDS YP_001282629.1 148661106 5214614 complement(1480509..1482134) 1 NC_009525.1 adenylate cyclase 1482134 5214614 MRA_1326 Mycobacterium tuberculosis H37Ra adenylate cyclase YP_001282629.1 1480509 R 419947 CDS YP_001282630.1 148661107 5215475 complement(1482204..1483811) 1 NC_009525.1 adenylate cyclase 1483811 5215475 MRA_1327 Mycobacterium tuberculosis H37Ra adenylate cyclase YP_001282630.1 1482204 R 419947 CDS YP_001282631.1 148661108 5215476 complement(1483824..1485527) 1 NC_009525.1 adenylate cyclase 1485527 5215476 MRA_1328 Mycobacterium tuberculosis H37Ra adenylate cyclase YP_001282631.1 1483824 R 419947 CDS YP_001282632.1 148661109 5215477 1485589..1486269 1 NC_009525.1 hypothetical protein 1486269 5215477 MRA_1329 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282632.1 1485589 D 419947 CDS YP_001282633.1 148661110 5215478 1486292..1486588 1 NC_009525.1 hypothetical protein 1486588 5215478 MRA_1329A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282633.1 1486292 D 419947 CDS YP_001282634.1 148661111 5215479 complement(1486623..1487081) 1 NC_009525.1 hypothetical protein 1487081 5215479 MRA_1330 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282634.1 1486623 R 419947 CDS YP_001282635.1 148661112 5215480 1487172..1488341 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 1488341 fadA4 5215480 fadA4 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001282635.1 1487172 D 419947 CDS YP_001282636.1 148661113 5215481 1488471..1489385 1 NC_009525.1 thioredoxin-related protein 1489385 5215481 MRA_1332 Mycobacterium tuberculosis H37Ra thioredoxin-related protein YP_001282636.1 1488471 D 419947 CDS YP_001282637.1 148661114 5215482 complement(1489464..1491275) 1 NC_009525.1 PE-PGRS family protein 1491275 5215482 MRA_1333 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282637.1 1489464 R 419947 CDS YP_001282638.1 148661115 5213433 complement(1491427..1493622) 1 NC_009525.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1493622 glgB 5213433 glgB Mycobacterium tuberculosis H37Ra glycogen branching enzyme YP_001282638.1 1491427 R 419947 CDS YP_001282639.1 148661116 5213434 complement(1493630..1495735) 1 NC_009525.1 glucanase GlgE 1495735 glgE 5213434 glgE Mycobacterium tuberculosis H37Ra glucanase GlgE YP_001282639.1 1493630 R 419947 CDS YP_001282640.1 148661117 5213435 1495874..1498465 1 NC_009525.1 glycogen phosphorylase 1498465 glgP 5213435 glgP Mycobacterium tuberculosis H37Ra glycogen phosphorylase YP_001282640.1 1495874 D 419947 CDS YP_001282641.1 148661118 5213436 complement(1498505..1500499) 1 NC_009525.1 ATP-dependent helicase DinG 1500499 dinG 5213436 dinG Mycobacterium tuberculosis H37Ra ATP-dependent helicase DinG YP_001282641.1 1498505 R 419947 CDS YP_001282642.1 148661119 5213437 complement(1500523..1501869) 1 NC_009525.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1501869 5213437 MRA_1338 Mycobacterium tuberculosis H37Ra nicotinate phosphoribosyltransferase YP_001282642.1 1500523 R 419947 CDS YP_001282643.1 148661120 5213438 1501971..1502276 1 NC_009525.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1502276 clpS 5213438 clpS Mycobacterium tuberculosis H37Ra ATP-dependent Clp protease adaptor protein ClpS YP_001282643.1 1501971 D 419947 CDS YP_001282644.1 148661121 5213439 1502236..1502892 1 NC_009525.1 transcriptional regulatory protein 1502892 5213439 MRA_1340 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282644.1 1502236 D 419947 CDS YP_001282645.1 148661122 5213440 1502909..1503943 1 NC_009525.1 hydrolase 1503943 5213440 MRA_1341 Mycobacterium tuberculosis H37Ra hydrolase YP_001282645.1 1502909 D 419947 CDS YP_001282646.1 148661123 5214112 1503951..1504391 1 NC_009525.1 hypothetical protein 1504391 5214112 MRA_1342 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282646.1 1503951 D 419947 CDS YP_001282647.1 148661124 5214113 1504413..1504694 1 NC_009525.1 antigen Cfp10A 1504694 cfp10a 5214113 cfp10a Mycobacterium tuberculosis H37Ra antigen Cfp10A YP_001282647.1 1504413 D 419947 CDS YP_001282648.1 148661125 5214114 1504704..1505675 1 NC_009525.1 cysteine synthase 1505675 cysM 5214114 cysM Mycobacterium tuberculosis H37Ra cysteine synthase YP_001282648.1 1504704 D 419947 CDS YP_001282649.1 148661126 5214115 1505666..1506388 1 NC_009525.1 integral membrane protein 1506388 5214115 MRA_1345 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001282649.1 1505666 D 419947 CDS YP_001282650.1 148661127 5214116 1506385..1507200 1 NC_009525.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1507200 murI 5214116 murI Mycobacterium tuberculosis H37Ra glutamate racemase YP_001282650.1 1506385 D 419947 CDS YP_001282651.1 148661128 5214117 1507227..1508048 1 NC_009525.1 hypothetical protein 1508048 5214117 MRA_1347 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282651.1 1507227 D 419947 CDS YP_001282652.1 148661129 5214118 1508065..1508844 1 NC_009525.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1508844 rph 5214118 rph Mycobacterium tuberculosis H37Ra ribonuclease PH YP_001282652.1 1508065 D 419947 CDS YP_001282653.1 148661130 5214119 1508883..1509497 1 NC_009525.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 1509497 5214119 MRA_1349 Mycobacterium tuberculosis H37Ra deoxyribonucleotide triphosphate pyrophosphatase YP_001282653.1 1508883 D 419947 CDS YP_001282654.1 148661131 5215633 complement(1509494..1509856) 1 NC_009525.1 hypothetical protein 1509856 5215633 MRA_1350 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282654.1 1509494 R 419947 CDS YP_001282655.1 148661132 5215634 complement(1509853..1510233) 1 NC_009525.1 lipoprotein LprD 1510233 lprD 5215634 lprD Mycobacterium tuberculosis H37Ra lipoprotein LprD YP_001282655.1 1509853 R 419947 CDS YP_001282656.1 148661133 5215635 1510278..1510598 1 NC_009525.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1510598 5215635 MRA_1352 Mycobacterium tuberculosis H37Ra acyl carrier protein YP_001282656.1 1510278 D 419947 CDS YP_001282657.1 148661134 5215636 1510591..1512156 1 NC_009525.1 converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; long-chain-fatty-acid--[acyl-carrier-protein] ligase 1512156 fadD33 5215636 fadD33 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--[acyl-carrier-protein] ligase YP_001282657.1 1510591 D 419947 CDS YP_001282658.1 148661135 5215637 1512156..1513316 1 NC_009525.1 acyl-CoA dehydrogenase 1513316 fadE14 5215637 fadE14 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001282658.1 1512156 D 419947 CDS YP_001282659.1 148661136 5215638 complement(1513283..1513915) 1 NC_009525.1 lysine N-acyltransferase MbtK 1513915 mbtK 5215638 mbtK Mycobacterium tuberculosis H37Ra lysine N-acyltransferase MbtK YP_001282659.1 1513283 R 419947 CDS YP_001282660.1 148661137 5215640 1514357..1516936 1 NC_009525.1 drugs ABC transporter ATP-binding protein 1516936 5215640 MRA_1356 Mycobacterium tuberculosis H37Ra drugs ABC transporter ATP-binding protein YP_001282660.1 1514357 D 419947 CDS YP_001282661.1 148661138 5212094 1516933..1518672 1 NC_009525.1 drugs ABC transporter ATP-binding protein 1518672 5212094 MRA_1357 Mycobacterium tuberculosis H37Ra drugs ABC transporter ATP-binding protein YP_001282661.1 1516933 D 419947 CDS YP_001282662.1 148661139 5212095 1518801..1519544 1 NC_009525.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1519544 fabG 5212095 fabG Mycobacterium tuberculosis H37Ra 3-ketoacyl-ACP reductase YP_001282662.1 1518801 D 419947 CDS YP_001282663.1 148661140 5212096 1519541..1519870 1 NC_009525.1 hypothetical protein 1519870 5212096 MRA_1359 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282663.1 1519541 D 419947 CDS YP_001282664.1 148661141 5212097 1520073..1520444 1 NC_009525.1 hypothetical protein 1520444 5212097 MRA_1360 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282664.1 1520073 D 419947 CDS YP_001282665.1 148661142 5212098 complement(1520510..1521295) 1 NC_009525.1 TetR/AcrR family transcriptional regulator 1521295 5212098 MRA_1361 Mycobacterium tuberculosis H37Ra TetR/AcrR family transcriptional regulator YP_001282665.1 1520510 R 419947 CDS YP_001282666.1 148661143 5212099 complement(1521315..1523186) 1 NC_009525.1 hypothetical protein 1523186 5212099 MRA_1362 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282666.1 1521315 R 419947 CDS YP_001282667.1 148661144 5212100 complement(1523195..1525342) 1 NC_009525.1 hypothetical protein 1525342 moeY 5212100 moeY Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282667.1 1523195 R 419947 CDS YP_001282668.1 148661145 5214464 complement(1525339..1526130) 1 NC_009525.1 hypothetical protein 1526130 5214464 MRA_1364 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282668.1 1525339 R 419947 CDS YP_001282669.1 148661146 5214465 complement(1526603..1527526) 1 NC_009525.1 hypothetical protein 1527526 5214465 MRA_1365 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282669.1 1526603 R 419947 CDS YP_001282670.1 148661147 5214466 1527922..1531401 1 NC_009525.1 LuxR family transcriptional regulator 1531401 5214466 MRA_1366 Mycobacterium tuberculosis H37Ra LuxR family transcriptional regulator YP_001282670.1 1527922 D 419947 CDS YP_001282671.1 148661148 5214467 1531483..1532235 1 NC_009525.1 transcriptional regulatory protein 1532235 5214467 MRA_1367 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282671.1 1531483 D 419947 CDS YP_001282672.1 148661149 5214468 complement(1532283..1532507) 1 NC_009525.1 hypothetical protein 1532507 5214468 MRA_1368 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282672.1 1532283 R 419947 CDS YP_001282673.1 148661150 5214469 1532658..1533680 1 NC_009525.1 N5,N10-methylenetetrahydromethanopterin reductase-related protein 1533680 5214469 MRA_1369 Mycobacterium tuberculosis H37Ra N5,N10-methylenetetrahydromethanopterin reductase-related protein YP_001282673.1 1532658 D 419947 CDS YP_001282674.1 148661151 5214470 complement(1533753..1534943) 1 NC_009525.1 PPE family protein 1534943 5214470 MRA_1370 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282674.1 1533753 R 419947 CDS YP_001282675.1 148661152 5214471 complement(1535258..1535920) 1 NC_009525.1 hypothetical protein 1535920 5214471 MRA_1371 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282675.1 1535258 R 419947 CDS YP_001282676.1 148661153 5213328 complement(1535917..1536702) 1 NC_009525.1 hypothetical protein 1536702 5213328 MRA_1372 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282676.1 1535917 R 419947 CDS YP_001282677.1 148661154 5213329 complement(1536993..1538954) 1 NC_009525.1 hypothetical protein 1538954 5213329 MRA_1373 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282677.1 1536993 R 419947 CDS YP_001282678.1 148661155 5213330 complement(1539093..1539479) 1 NC_009525.1 anti-anti-sigma factor RsfA 1539479 rsfA 5213330 rsfA Mycobacterium tuberculosis H37Ra anti-anti-sigma factor RsfA YP_001282678.1 1539093 R 419947 CDS YP_001282679.1 148661156 5213331 1539700..1540521 1 NC_009525.1 hypothetical protein 1540521 5213331 MRA_1375 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282679.1 1539700 D 419947 CDS YP_001282680.1 148661157 5213332 1540490..1540750 1 NC_009525.1 hypothetical protein 1540750 5213332 MRA_1376 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282680.1 1540490 D 419947 CDS YP_001282681.1 148661158 5213333 complement(1540822..1541955) 1 NC_009525.1 hypothetical protein 1541955 5213333 MRA_1377 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282681.1 1540822 R 419947 CDS YP_001282682.1 148661159 5213334 1542330..1543115 1 NC_009525.1 lipoprotein LprF 1543115 lprF 5213334 lprF Mycobacterium tuberculosis H37Ra lipoprotein LprF YP_001282682.1 1542330 D 419947 CDS YP_001282683.1 148661160 5213335 complement(1543304..1544188) 1 NC_009525.1 IS6110 transposase 1544188 5213335 MRA_1379 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001282683.1 1543304 R 419947 CDS YP_001282684.1 148661161 5215099 complement(1544239..1544565) 1 NC_009525.1 IS6110 hypothetical protein 1544565 5215099 MRA_1380 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001282684.1 1544239 R 419947 CDS YP_001282685.1 148661162 5215100 1544669..1546138 1 NC_009525.1 desaturase-related protein 1546138 5215100 MRA_1381 Mycobacterium tuberculosis H37Ra desaturase-related protein YP_001282685.1 1544669 D 419947 CDS YP_001282686.1 148661163 5215101 1546135..1547316 1 NC_009525.1 hypothetical protein 1547316 5215101 MRA_1382 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282686.1 1546135 D 419947 CDS YP_001282687.1 148661164 5215102 1547322..1548302 1 NC_009525.1 glycolipid sulfotransferase 1548302 5215102 MRA_1383 Mycobacterium tuberculosis H37Ra glycolipid sulfotransferase YP_001282687.1 1547322 D 419947 CDS YP_001282688.1 148661165 5215103 complement(1548382..1548840) 1 NC_009525.1 hypothetical protein 1548840 5215103 MRA_1383A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282688.1 1548382 R 419947 CDS YP_001282689.1 148661166 5215104 1549142..1550461 1 NC_009525.1 hypothetical protein 1550461 5215104 MRA_1384 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282689.1 1549142 D 419947 CDS YP_001282690.1 148661167 5215105 1550458..1551951 1 NC_009525.1 hypothetical protein 1551951 5215105 MRA_1385 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282690.1 1550458 D 419947 CDS YP_001282691.1 148661168 5212064 complement(1551889..1552527) 1 NC_009525.1 hypothetical protein 1552527 5212064 MRA_1386 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282691.1 1551889 R 419947 CDS YP_001282692.1 148661169 5212065 complement(1552538..1553965) 1 NC_009525.1 hypothetical protein 1553965 5212065 MRA_1387 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282692.1 1552538 R 419947 CDS YP_001282693.1 148661170 5212066 1553964..1554545 1 NC_009525.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 1554545 pyrR 5212066 pyrR Mycobacterium tuberculosis H37Ra bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_001282693.1 1553964 D 419947 CDS YP_001282694.1 148661171 5212067 1554542..1555501 1 NC_009525.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1555501 pyrB 5212067 pyrB Mycobacterium tuberculosis H37Ra aspartate carbamoyltransferase YP_001282694.1 1554542 D 419947 CDS YP_001282695.1 148661172 5212068 1555498..1556790 1 NC_009525.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1556790 pyrC 5212068 pyrC Mycobacterium tuberculosis H37Ra dihydroorotase YP_001282695.1 1555498 D 419947 CDS YP_001282696.1 148661173 5212069 1556787..1557284 1 NC_009525.1 export protein 1557284 5212069 MRA_1391 Mycobacterium tuberculosis H37Ra export protein YP_001282696.1 1556787 D 419947 CDS YP_001282697.1 148661174 5212070 1557281..1558411 1 NC_009525.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1558411 carA 5212070 carA Mycobacterium tuberculosis H37Ra carbamoyl phosphate synthase small subunit YP_001282697.1 1557281 D 419947 CDS YP_001282698.1 148661175 5212071 1558411..1561758 1 NC_009525.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1561758 carB 5212071 carB Mycobacterium tuberculosis H37Ra carbamoyl phosphate synthase large subunit YP_001282698.1 1558411 D 419947 CDS YP_001282699.1 148661176 5212358 1561755..1562579 1 NC_009525.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1562579 pyrF 5212358 pyrF Mycobacterium tuberculosis H37Ra orotidine 5'-phosphate decarboxylase YP_001282699.1 1561755 D 419947 CDS YP_001282700.1 148661177 5212359 1562774..1563082 1 NC_009525.1 PE family protein 1563082 5212359 MRA_1395 Mycobacterium tuberculosis H37Ra PE family protein YP_001282700.1 1562774 D 419947 CDS YP_001282701.1 148661178 5212360 1563079..1564698 1 NC_009525.1 PPE family protein 1564698 5212360 MRA_1396 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282701.1 1563079 D 419947 CDS YP_001282702.1 148661179 5212361 1565004..1565576 1 NC_009525.1 integration host factor MihF 1565576 mihF 5212361 mihF Mycobacterium tuberculosis H37Ra integration host factor MihF YP_001282702.1 1565004 D 419947 CDS YP_001282703.1 148661180 5212362 1565711..1566337 1 NC_009525.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1566337 gmk 5212362 gmk Mycobacterium tuberculosis H37Ra guanylate kinase YP_001282703.1 1565711 D 419947 CDS YP_001282704.1 148661181 5212363 1566403..1566735 1 NC_009525.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1566735 rpoZ 5212363 rpoZ Mycobacterium tuberculosis H37Ra DNA-directed RNA polymerase subunit omega YP_001282704.1 1566403 D 419947 CDS YP_001282705.1 148661182 5212364 1566751..1568007 1 NC_009525.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1568007 dfp 5212364 dfp Mycobacterium tuberculosis H37Ra bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001282705.1 1566751 D 419947 CDS YP_001282706.1 148661183 5213043 1568135..1569346 1 NC_009525.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1569346 metK 5213043 metK Mycobacterium tuberculosis H37Ra S-adenosylmethionine synthetase YP_001282706.1 1568135 D 419947 CDS YP_001282707.1 148661184 5213044 complement(1569419..1570897) 1 NC_009525.1 monooxygenase 1570897 5213044 MRA_1402 Mycobacterium tuberculosis H37Ra monooxygenase YP_001282707.1 1569419 R 419947 CDS YP_001282708.1 148661185 5213045 complement(1570894..1572279) 1 NC_009525.1 cytochrome p450 132 CYP132 1572279 cyp132 5213045 cyp132 Mycobacterium tuberculosis H37Ra cytochrome p450 132 CYP132 YP_001282708.1 1570894 R 419947 CDS YP_001282709.1 148661186 5213046 1572357..1573391 1 NC_009525.1 transcriptional regulatory protein 1573391 5213046 MRA_1404 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282709.1 1572357 D 419947 CDS YP_001282710.1 148661187 5213047 complement(1573437..1575230) 1 NC_009525.1 PE-PGRS family protein 1575230 5213047 MRA_1405 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282710.1 1573437 R 419947 CDS YP_001282711.1 148661188 5213048 complement(1575422..1575823) 1 NC_009525.1 hypothetical protein 1575823 5213048 MRA_1406 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282711.1 1575422 R 419947 CDS YP_001282712.1 148661189 5213049 complement(1575820..1576077) 1 NC_009525.1 hypothetical protein 1576077 5213049 MRA_1407 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282712.1 1575820 R 419947 CDS YP_001282713.1 148661190 5213050 complement(1576160..1577119) 1 NC_009525.1 lipase LipH 1577119 lipH 5213050 lipH Mycobacterium tuberculosis H37Ra lipase LipH YP_001282713.1 1576160 R 419947 CDS YP_001282714.1 148661191 5214431 complement(1577144..1578106) 1 NC_009525.1 lipase/esterase 1578106 lipI 5214431 lipI Mycobacterium tuberculosis H37Ra lipase/esterase YP_001282714.1 1577144 R 419947 CDS YP_001282715.1 148661192 5214432 1578240..1578842 1 NC_009525.1 hypothetical protein 1578842 5214432 MRA_1410 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282715.1 1578240 D 419947 CDS YP_001282716.1 148661193 5214433 1578923..1580890 1 NC_009525.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1580890 priA 5214433 priA Mycobacterium tuberculosis H37Ra primosome assembly protein PriA YP_001282716.1 1578923 D 419947 CDS YP_001282717.1 148661194 5214434 complement(1580908..1581732) 1 NC_009525.1 methyltransferase 1581732 5214434 MRA_1412 Mycobacterium tuberculosis H37Ra methyltransferase YP_001282717.1 1580908 R 419947 CDS YP_001282718.1 148661195 5214435 1581901..1582383 1 NC_009525.1 transcriptional regulatory protein 1582383 5214435 MRA_1413 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282718.1 1581901 D 419947 CDS YP_001282719.1 148661196 5214436 complement(1582455..1583279) 1 NC_009525.1 methyltransferase 1583279 5214436 MRA_1414 Mycobacterium tuberculosis H37Ra methyltransferase YP_001282719.1 1582455 R 419947 CDS YP_001282720.1 148661197 5214437 1583476..1584414 1 NC_009525.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1584414 fmt 5214437 fmt Mycobacterium tuberculosis H37Ra methionyl-tRNA formyltransferase YP_001282720.1 1583476 D 419947 CDS YP_001282721.1 148661198 5213342 1584411..1585784 1 NC_009525.1 Fmu protein 1585784 fmu 5213342 fmu Mycobacterium tuberculosis H37Ra Fmu protein YP_001282721.1 1584411 D 419947 CDS YP_001282722.1 148661199 5213343 1585809..1586507 1 NC_009525.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1586507 rpe 5213343 rpe Mycobacterium tuberculosis H37Ra ribulose-phosphate 3-epimerase YP_001282722.1 1585809 D 419947 CDS YP_001282723.1 148661200 5213344 1586504..1587523 1 NC_009525.1 riboflavin-specific deaminase 1587523 ribG 5213344 ribG Mycobacterium tuberculosis H37Ra riboflavin-specific deaminase YP_001282723.1 1586504 D 419947 CDS YP_001282724.1 148661201 5213345 complement(1587520..1589076) 1 NC_009525.1 aminoglycosides/tetracycline-transport integral membrane protein 1589076 5213345 MRA_1419 Mycobacterium tuberculosis H37Ra aminoglycosides/tetracycline-transport integral membrane protein YP_001282724.1 1587520 R 419947 CDS YP_001282725.1 148661202 5213346 complement(1589082..1589792) 1 NC_009525.1 lipoprotein LprG 1589792 lprG 5213346 lprG Mycobacterium tuberculosis H37Ra lipoprotein LprG YP_001282725.1 1589082 R 419947 CDS YP_001282726.1 148661203 5213347 1589877..1590482 1 NC_009525.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1590482 ribC 5213347 ribC Mycobacterium tuberculosis H37Ra riboflavin synthase subunit alpha YP_001282726.1 1589877 D 419947 CDS YP_001282727.1 148661204 5213348 1590696..1591211 1 NC_009525.1 hypothetical protein 1591211 5213348 MRA_1422 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282727.1 1590696 D 419947 CDS YP_001282728.1 148661205 5213349 1591201..1591602 1 NC_009525.1 hypothetical protein 1591602 5213349 MRA_1423 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282728.1 1591201 D 419947 CDS YP_001282729.1 148661206 5212108 1591707..1592984 1 NC_009525.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 1592984 ribA2 5212108 ribA2 Mycobacterium tuberculosis H37Ra bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein YP_001282729.1 1591707 D 419947 CDS YP_001282730.1 148661207 5212109 1592999..1593463 1 NC_009525.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1593463 ribH 5212109 ribH Mycobacterium tuberculosis H37Ra 6,7-dimethyl-8-ribityllumazine synthase YP_001282730.1 1592999 D 419947 CDS YP_001282731.1 148661208 5212110 1593460..1593924 1 NC_009525.1 hypothetical protein 1593924 5212110 MRA_1426 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282731.1 1593460 D 419947 CDS YP_001282732.1 148661209 5212111 1593949..1594635 1 NC_009525.1 lipoprotein LprH 1594635 lprH 5212111 lprH Mycobacterium tuberculosis H37Ra lipoprotein LprH YP_001282732.1 1593949 D 419947 CDS YP_001282733.1 148661210 5212112 1594815..1595288 1 NC_009525.1 hypothetical protein 1595288 5212112 MRA_1428 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282733.1 1594815 D 419947 CDS YP_001282734.1 148661211 5212113 1595352..1597292 1 NC_009525.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1597292 uvrC 5212113 uvrC Mycobacterium tuberculosis H37Ra excinuclease ABC subunit C YP_001282734.1 1595352 D 419947 CDS YP_001282735.1 148661212 5212114 1597289..1598194 1 NC_009525.1 hypothetical protein 1598194 5212114 MRA_1430 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282735.1 1597289 D 419947 CDS YP_001282736.1 148661213 5215688 1598191..1599219 1 NC_009525.1 hypothetical protein 1599219 5215688 MRA_1431 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282736.1 1598191 D 419947 CDS YP_001282737.1 148661214 5215689 1599216..1600193 1 NC_009525.1 transcriptional regulatory protein WhiA 1600193 whiA 5215689 whiA Mycobacterium tuberculosis H37Ra transcriptional regulatory protein WhiA YP_001282737.1 1599216 D 419947 CDS YP_001282738.1 148661215 5215690 complement(1600203..1600964) 1 NC_009525.1 hypothetical protein 1600964 5215690 MRA_1433 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282738.1 1600203 R 419947 CDS YP_001282739.1 148661216 5215691 1600968..1602347 1 NC_009525.1 hypothetical protein 1602347 5215691 MRA_1434 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282739.1 1600968 D 419947 CDS YP_001282740.1 148661217 5215692 complement(1602369..1603631) 1 NC_009525.1 esterase 1603631 lipO 5215692 lipO Mycobacterium tuberculosis H37Ra esterase YP_001282740.1 1602369 R 419947 CDS YP_001282741.1 148661218 5215693 complement(1603631..1605238) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1605238 fadD12 5215693 fadD12 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001282741.1 1603631 R 419947 CDS YP_001282742.1 148661219 5215694 complement(1605242..1606069) 1 NC_009525.1 hypothetical protein 1606069 5215694 MRA_1437 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282742.1 1605242 R 419947 CDS YP_001282743.1 148661220 5215695 1606188..1607456 1 NC_009525.1 hypothetical protein 1607456 5215695 MRA_1438 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282743.1 1606188 D 419947 CDS YP_001282744.1 148661221 5211774 1607696..1609282 1 NC_009525.1 PE family protein 1609282 5211774 MRA_1439 Mycobacterium tuberculosis H37Ra PE family protein YP_001282744.1 1607696 D 419947 CDS YP_001282745.1 148661222 5211775 1609393..1611162 1 NC_009525.1 hypothetical protein 1611162 5211775 MRA_1440 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282745.1 1609393 D 419947 CDS YP_001282746.1 148661223 5211776 1611159..1612580 1 NC_009525.1 dehydrogenase 1612580 5211776 MRA_1441 Mycobacterium tuberculosis H37Ra dehydrogenase YP_001282746.1 1611159 D 419947 CDS YP_001282747.1 148661224 5211777 1612744..1613559 1 NC_009525.1 hypothetical protein 1613559 5211777 MRA_1442 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282747.1 1612744 D 419947 CDS YP_001282748.1 148661225 5211778 1613566..1613703 1 NC_009525.1 hypothetical protein 1613703 5211778 MRA_1442A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282748.1 1613566 D 419947 CDS YP_001282749.1 148661226 5211779 complement(1613652..1614260) 1 NC_009525.1 hypothetical protein 1614260 5211779 MRA_1443 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282749.1 1613652 R 419947 CDS YP_001282750.1 148661227 5211780 1614617..1615636 1 NC_009525.1 glyceraldehyde-3-phosphate dehydrogenase 1615636 gap 5211780 gap Mycobacterium tuberculosis H37Ra glyceraldehyde-3-phosphate dehydrogenase YP_001282750.1 1614617 D 419947 CDS YP_001282751.1 148661228 5211781 1615639..1616877 1 NC_009525.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1616877 pgk 5211781 pgk Mycobacterium tuberculosis H37Ra phosphoglycerate kinase YP_001282751.1 1615639 D 419947 CDS YP_001282752.1 148661229 5213557 1616874..1617659 1 NC_009525.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1617659 tpiA 5213557 tpiA Mycobacterium tuberculosis H37Ra triosephosphate isomerase YP_001282752.1 1616874 D 419947 CDS YP_001282753.1 148661230 5213558 complement(1618271..1618696) 1 NC_009525.1 hypothetical protein 1618696 5213558 MRA_1447 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282753.1 1618271 R 419947 CDS YP_001282754.1 148661231 5213559 1618967..1619380 1 NC_009525.1 protein-export membrane protein 1619380 secG 5213559 secG Mycobacterium tuberculosis H37Ra protein-export membrane protein YP_001282754.1 1618967 D 419947 CDS YP_001282755.1 148661232 5213560 complement(1619519..1620982) 1 NC_009525.1 PE-PGRS family protein 1620982 5213560 MRA_1449 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282755.1 1619519 R 419947 CDS YP_001282756.1 148661233 5213561 1621101..1623401 1 NC_009525.1 biotin sulfoxide reductase BisC 1623401 bisC 5213561 bisC Mycobacterium tuberculosis H37Ra biotin sulfoxide reductase BisC YP_001282756.1 1621101 D 419947 CDS YP_001282757.1 148661234 5213562 complement(1623517..1624002) 1 NC_009525.1 hypothetical protein 1624002 5213562 MRA_1451 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282757.1 1623517 R 419947 CDS YP_001282758.1 148661235 5213563 1624078..1624317 1 NC_009525.1 hypothetical protein 1624317 5213563 MRA_1452 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282758.1 1624078 D 419947 CDS YP_001282759.1 148661236 5213564 complement(1624597..1625007) 1 NC_009525.1 hypothetical protein 1625007 5213564 MRA_1453 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282759.1 1624597 R 419947 CDS YP_001282760.1 148661237 5215346 complement(1625024..1625767) 1 NC_009525.1 6-phosphogluconolactonase 1625767 devB 5215346 devB Mycobacterium tuberculosis H37Ra 6-phosphogluconolactonase YP_001282760.1 1625024 R 419947 CDS YP_001282761.1 148661238 5215347 complement(1625764..1626675) 1 NC_009525.1 oxppcycle protein OpcA 1626675 opcA 5215347 opcA Mycobacterium tuberculosis H37Ra oxppcycle protein OpcA YP_001282761.1 1625764 R 419947 CDS YP_001282762.1 148661239 5215348 complement(1626728..1628272) 1 NC_009525.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1628272 zwf2 5215348 zwf2 Mycobacterium tuberculosis H37Ra glucose-6-phosphate 1-dehydrogenase YP_001282762.1 1626728 R 419947 CDS YP_001282763.1 148661240 5215349 complement(1628269..1629390) 1 NC_009525.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 1629390 tal 5215349 tal Mycobacterium tuberculosis H37Ra transaldolase YP_001282763.1 1628269 R 419947 CDS YP_001282764.1 148661241 5215350 complement(1629407..1631509) 1 NC_009525.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1631509 tkt 5215350 tkt Mycobacterium tuberculosis H37Ra transketolase YP_001282764.1 1629407 R 419947 CDS YP_001282765.1 148661242 5215351 complement(1631948..1636144) 1 NC_009525.1 PE-PGRS family protein 1636144 5215351 MRA_1459 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282765.1 1631948 R 419947 CDS YP_001282766.1 148661243 5215352 1636546..1637472 1 NC_009525.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 1637472 ctaB 5215352 ctaB Mycobacterium tuberculosis H37Ra protoheme IX farnesyltransferase YP_001282766.1 1636546 D 419947 CDS YP_001282767.1 148661244 5215459 complement(1637521..1639746) 1 NC_009525.1 PE-PGRS family protein 1639746 5215459 MRA_1461 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282767.1 1637521 R 419947 CDS YP_001282768.1 148661245 5215460 1639898..1641163 1 NC_009525.1 hypothetical protein 1641163 5215460 MRA_1462 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282768.1 1639898 D 419947 CDS YP_001282769.1 148661246 5215461 complement(1641191..1642177) 1 NC_009525.1 quinone reductase Qor 1642177 qor 5215461 qor Mycobacterium tuberculosis H37Ra quinone reductase Qor YP_001282769.1 1641191 R 419947 CDS YP_001282770.1 148661247 5215462 1642197..1643060 1 NC_009525.1 hypothetical protein 1643060 5215462 MRA_1464 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282770.1 1642197 D 419947 CDS YP_001282771.1 148661248 5215463 complement(1643010..1643942) 1 NC_009525.1 antibiotic ABC transporter permease 1643942 5215463 MRA_1465 Mycobacterium tuberculosis H37Ra antibiotic ABC transporter permease YP_001282771.1 1643010 R 419947 CDS YP_001282772.1 148661249 5215464 complement(1644054..1644839) 1 NC_009525.1 antibiotic ABC transporter permease 1644839 5215464 MRA_1466 Mycobacterium tuberculosis H37Ra antibiotic ABC transporter permease YP_001282772.1 1644054 R 419947 CDS YP_001282773.1 148661250 5215465 complement(1644836..1645777) 1 NC_009525.1 antibiotic ABC transporter ATP-binding protein 1645777 5215465 MRA_1467 Mycobacterium tuberculosis H37Ra antibiotic ABC transporter ATP-binding protein YP_001282773.1 1644836 R 419947 CDS YP_001282774.1 148661251 5215466 complement(1645880..1647655) 1 NC_009525.1 integral membrane protein 1647655 5215466 MRA_1468 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001282774.1 1645880 R 419947 CDS YP_001282775.1 148661252 5212217 1647703..1648509 1 NC_009525.1 transcriptional regulatory protein 1648509 5212217 MRA_1469 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282775.1 1647703 D 419947 CDS YP_001282776.1 148661253 5212218 1648506..1651046 1 NC_009525.1 iron-regulated ABC transporter permease 1651046 5212218 MRA_1470 Mycobacterium tuberculosis H37Ra iron-regulated ABC transporter permease YP_001282776.1 1648506 D 419947 CDS YP_001282777.1 148661254 5212219 1651043..1652236 1 NC_009525.1 hypothetical protein 1652236 5212219 MRA_1471 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282777.1 1651043 D 419947 CDS YP_001282778.1 148661255 5212220 1652233..1653033 1 NC_009525.1 iron-regulated ABC transporter ATP-binding protein 1653033 5212220 MRA_1472 Mycobacterium tuberculosis H37Ra iron-regulated ABC transporter ATP-binding protein YP_001282778.1 1652233 D 419947 CDS YP_001282779.1 148661256 5212221 1653035..1654288 1 NC_009525.1 cysteine desulfurase Csd 1654288 csd 5212221 csd Mycobacterium tuberculosis H37Ra cysteine desulfurase Csd YP_001282779.1 1653035 D 419947 CDS YP_001282780.1 148661257 5212222 1654285..1654773 1 NC_009525.1 nitrogen fixation protein NifU-related protein 1654773 5212222 MRA_1474 Mycobacterium tuberculosis H37Ra nitrogen fixation protein NifU-related protein YP_001282780.1 1654285 D 419947 CDS YP_001282781.1 148661258 5212223 1654748..1655095 1 NC_009525.1 hypothetical protein 1655095 5212223 MRA_1475 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282781.1 1654748 D 419947 CDS YP_001282782.1 148661259 5212224 complement(1655190..1657019) 1 NC_009525.1 acyl-CoA dehydrogenase 1657019 fadE15 5212224 fadE15 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001282782.1 1655190 R 419947 CDS YP_001282783.1 148661260 5213736 complement(1657126..1658238) 1 NC_009525.1 PE-PGRS family protein 1658238 5213736 MRA_1477 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282783.1 1657126 R 419947 CDS YP_001282784.1 148661261 5213737 1658480..1660453 1 NC_009525.1 metal cation transporting P-type ATPase CtpD 1660453 ctpD 5213737 ctpD Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpD YP_001282784.1 1658480 D 419947 CDS YP_001282785.1 148661262 5213738 1660497..1660871 1 NC_009525.1 thioredoxin TrxA 1660871 trxA 5213738 trxA Mycobacterium tuberculosis H37Ra thioredoxin TrxA YP_001282785.1 1660497 D 419947 CDS YP_001282786.1 148661263 5213739 1660887..1661258 1 NC_009525.1 thioredoxin TrxB1 1661258 trxB1 5213739 trxB1 Mycobacterium tuberculosis H37Ra thioredoxin TrxB1 YP_001282786.1 1660887 D 419947 CDS YP_001282787.1 148661264 5213740 1661280..1662137 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1662137 echA12 5213740 echA12 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001282787.1 1661280 D 419947 CDS YP_001282788.1 148661265 5213741 1662173..1663801 1 NC_009525.1 macrolide ABC transporter ATP-binding protein 1663801 5213741 MRA_1482 Mycobacterium tuberculosis H37Ra macrolide ABC transporter ATP-binding protein YP_001282788.1 1662173 D 419947 CDS YP_001282789.1 148661266 5213742 1663898..1664089 1 NC_009525.1 transcriptional regulatory protein 1664089 5213742 MRA_1483 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282789.1 1663898 D 419947 CDS YP_001282790.1 148661267 5213244 complement(1664158..1664721) 1 NC_009525.1 transcriptional regulatory protein 1664721 5213244 MRA_1484 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001282790.1 1664158 R 419947 CDS YP_001282791.1 148661268 5213245 complement(1664732..1667563) 1 NC_009525.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1667563 acn 5213245 acn Mycobacterium tuberculosis H37Ra aconitate hydratase YP_001282791.1 1664732 R 419947 CDS YP_001282792.1 148661269 5213246 1667721..1668281 1 NC_009525.1 hypothetical protein 1668281 5213246 MRA_1486 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282792.1 1667721 D 419947 CDS YP_001282793.1 148661270 5213247 1668507..1669925 1 NC_009525.1 invasion protein 1669925 5213247 MRA_1487 Mycobacterium tuberculosis H37Ra invasion protein YP_001282793.1 1668507 D 419947 CDS YP_001282794.1 148661271 5213248 1669936..1670661 1 NC_009525.1 invasion protein 1670661 5213248 MRA_1488 Mycobacterium tuberculosis H37Ra invasion protein YP_001282794.1 1669936 D 419947 CDS YP_001282795.1 148661272 5213249 1670800..1671933 1 NC_009525.1 transcriptional regulatory protein MoxR1 1671933 moxR1 5213249 moxR1 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein MoxR1 YP_001282795.1 1670800 D 419947 CDS YP_001282796.1 148661273 5213250 1671930..1672883 1 NC_009525.1 hypothetical protein 1672883 5213250 MRA_1490 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282796.1 1671930 D 419947 CDS YP_001282797.1 148661274 5213251 1672894..1673901 1 NC_009525.1 hypothetical protein 1673901 5213251 MRA_1491 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282797.1 1672894 D 419947 CDS YP_001282798.1 148661275 5215047 complement(1673974..1674816) 1 NC_009525.1 hypothetical protein 1674816 5215047 MRA_1492 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282798.1 1673974 R 419947 CDS YP_001282799.1 148661276 5215048 1674957..1675700 1 NC_009525.1 3-oxoacyl-ACP reductase 1675700 fabG1 5215048 fabG1 Mycobacterium tuberculosis H37Ra 3-oxoacyl-ACP reductase YP_001282799.1 1674957 D 419947 CDS YP_001282800.1 148661277 5215049 1675719..1676528 1 NC_009525.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1676528 inhA 5215049 inhA Mycobacterium tuberculosis H37Ra enoyl-ACP reductase YP_001282800.1 1675719 D 419947 CDS YP_001282801.1 148661278 5215050 1676534..1677568 1 NC_009525.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1677568 hemH 5215050 hemH Mycobacterium tuberculosis H37Ra ferrochelatase YP_001282801.1 1676534 D 419947 CDS YP_001282802.1 148661279 5215051 complement(1677534..1678400) 1 NC_009525.1 hypothetical protein 1678400 5215051 MRA_1495A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282802.1 1677534 R 419947 CDS YP_001282803.1 148661280 5215052 1678458..1678892 1 NC_009525.1 hypothetical protein 1678892 5215052 MRA_1496 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282803.1 1678458 D 419947 CDS YP_001282804.1 148661281 5215053 1678914..1680059 1 NC_009525.1 hypothetical protein 1680059 5215053 MRA_1497 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282804.1 1678914 D 419947 CDS YP_001282805.1 148661282 5215054 1680069..1680425 1 NC_009525.1 hypothetical protein 1680425 5215054 MRA_1498 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282805.1 1680069 D 419947 CDS YP_001282806.1 148661283 5215246 1680459..1680689 1 NC_009525.1 hypothetical protein 1680689 5215246 MRA_1499 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282806.1 1680459 D 419947 CDS YP_001282807.1 148661284 5215247 1680839..1682146 1 NC_009525.1 hypothetical protein 1682146 5215247 MRA_1500 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282807.1 1680839 D 419947 CDS YP_001282808.1 148661285 5215248 complement(1682725..1683483) 1 NC_009525.1 hypothetical protein 1683483 5215248 MRA_1501 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282808.1 1682725 R 419947 CDS YP_001282809.1 148661286 5215249 1683674..1685521 1 NC_009525.1 methylmalonyl-CoA mutase small subunit MutA 1685521 mutA 5215249 mutA Mycobacterium tuberculosis H37Ra methylmalonyl-CoA mutase small subunit MutA YP_001282809.1 1683674 D 419947 CDS YP_001282810.1 148661287 5215250 1685522..1687774 1 NC_009525.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 1687774 mutB 5215250 mutB Mycobacterium tuberculosis H37Ra methylmalonyl-CoA mutase YP_001282810.1 1685522 D 419947 CDS YP_001282811.1 148661288 5215251 1687788..1688090 1 NC_009525.1 hypothetical protein 1688090 5215251 MRA_1504 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282811.1 1687788 D 419947 CDS YP_001282812.1 148661289 5215252 1688087..1688404 1 NC_009525.1 hypothetical protein 1688404 5215252 MRA_1505 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282812.1 1688087 D 419947 CDS YP_001282813.1 148661290 5215398 1688401..1689405 1 NC_009525.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 1689405 5215398 MRA_1506 Mycobacterium tuberculosis H37Ra arginine/ornithine transport system ATPase YP_001282813.1 1688401 D 419947 CDS YP_001282814.1 148661291 5215399 1689458..1690747 1 NC_009525.1 esterase LipL 1690747 lipL 5215399 lipL Mycobacterium tuberculosis H37Ra esterase LipL YP_001282814.1 1689458 D 419947 CDS YP_001282815.1 148661292 5215400 complement(1690820..1691437) 1 NC_009525.1 methyltransferase 1691437 5215400 MRA_1508 Mycobacterium tuberculosis H37Ra methyltransferase YP_001282815.1 1690820 R 419947 CDS YP_001282816.1 148661293 5215401 complement(1691651..1691863) 1 NC_009525.1 hypothetical protein 1691863 5215401 MRA_1509 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282816.1 1691651 R 419947 CDS YP_001282817.1 148661294 5215402 1691924..1692322 1 NC_009525.1 hypothetical protein 1692322 5215402 MRA_1510 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282817.1 1691924 D 419947 CDS YP_001282818.1 148661295 5215403 1692367..1693395 1 NC_009525.1 dolichol-phosphate mannosyltransferase 1693395 5215403 MRA_1511 Mycobacterium tuberculosis H37Ra dolichol-phosphate mannosyltransferase YP_001282818.1 1692367 D 419947 CDS YP_001282819.1 148661296 5215404 1693407..1694228 1 NC_009525.1 hypothetical protein 1694228 5215404 MRA_1512 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282819.1 1693407 D 419947 CDS YP_001282820.1 148661297 5215405 1694441..1695340 1 NC_009525.1 hypothetical protein 1695340 5215405 MRA_1513 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282820.1 1694441 D 419947 CDS YP_001282821.1 148661298 5213252 complement(1695513..1695953) 1 NC_009525.1 hypothetical protein 1695953 5213252 MRA_1514 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282821.1 1695513 R 419947 CDS YP_001282822.1 148661299 5213253 complement(1696062..1696661) 1 NC_009525.1 hypothetical protein 1696661 5213253 MRA_1515 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282822.1 1696062 R 419947 CDS YP_001282823.1 148661300 5213254 complement(1696798..1697463) 1 NC_009525.1 hypothetical protein 1697463 5213254 MRA_1516 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282823.1 1696798 R 419947 CDS YP_001282824.1 148661301 5213255 complement(1697460..1697960) 1 NC_009525.1 hypothetical protein 1697960 5213255 MRA_1517 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282824.1 1697460 R 419947 CDS YP_001282825.1 148661302 5213256 complement(1698244..1698939) 1 NC_009525.1 hypothetical protein 1698939 5213256 MRA_1518 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282825.1 1698244 R 419947 CDS YP_001282826.1 148661303 5213257 complement(1699612..1701411) 1 NC_009525.1 hypothetical protein 1701411 5213257 MRA_1519 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282826.1 1699612 R 419947 CDS YP_001282827.1 148661304 5213258 1701383..1701745 1 NC_009525.1 hypothetical protein 1701745 5213258 MRA_1520 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282827.1 1701383 D 419947 CDS YP_001282828.1 148661305 5213259 1701729..1702610 1 NC_009525.1 hypothetical protein 1702610 5213259 MRA_1521 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282828.1 1701729 D 419947 CDS YP_001282829.1 148661306 5212009 1702812..1704110 1 NC_009525.1 hypothetical protein 1704110 5212009 MRA_1522 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282829.1 1702812 D 419947 CDS YP_001282830.1 148661307 5212010 1704591..1705613 1 NC_009525.1 GDP-D-mannose dehydratase 1705613 gmdA 5212010 gmdA Mycobacterium tuberculosis H37Ra GDP-D-mannose dehydratase YP_001282830.1 1704591 D 419947 CDS YP_001282831.1 148661308 5212011 1705610..1706578 1 NC_009525.1 fucose synthetase 1706578 epiA 5212011 epiA Mycobacterium tuberculosis H37Ra fucose synthetase YP_001282831.1 1705610 D 419947 CDS YP_001282832.1 148661309 5212012 1706575..1707306 1 NC_009525.1 hypothetical protein 1707306 5212012 MRA_1525 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282832.1 1706575 D 419947 CDS YP_001282833.1 148661310 5212013 complement(1707324..1708112) 1 NC_009525.1 hypothetical protein 1708112 5212013 MRA_1526 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282833.1 1707324 R 419947 CDS YP_001282834.1 148661311 5212014 complement(1708147..1709043) 1 NC_009525.1 hypothetical protein 1709043 5212014 MRA_1527 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282834.1 1708147 R 419947 CDS YP_001282835.1 148661312 5212015 complement(1709046..1710056) 1 NC_009525.1 glycosyl transferase 1710056 5212015 MRA_1528 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001282835.1 1709046 R 419947 CDS YP_001282836.1 148661313 5212016 1710388..1711152 1 NC_009525.1 hypothetical protein 1711152 5212016 MRA_1529 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282836.1 1710388 D 419947 CDS YP_001282837.1 148661314 5214211 1711161..1712120 1 NC_009525.1 hypothetical protein 1712120 5214211 MRA_1530 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282837.1 1711161 D 419947 CDS YP_001282838.1 148661315 5214212 1712250..1712519 1 NC_009525.1 hypothetical protein 1712519 5214212 MRA_1531 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282838.1 1712250 D 419947 CDS YP_001282839.1 148661316 5214213 1712545..1713585 1 NC_009525.1 glycosyl transferase 1713585 5214213 MRA_1532 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001282839.1 1712545 D 419947 CDS YP_001282840.1 148661317 5214214 1713819..1715570 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1715570 fadD25 5214214 fadD25 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001282840.1 1713819 D 419947 CDS YP_001282841.1 148661318 5214215 complement(1715689..1719129) 1 NC_009525.1 transmembrane transport protein MmpL12 1719129 mmpL12 5214215 mmpL12 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL12 YP_001282841.1 1715689 R 419947 CDS YP_001282842.1 148661319 5214216 1719170..1720213 1 NC_009525.1 methyltransferase 1720213 5214216 MRA_1535 Mycobacterium tuberculosis H37Ra methyltransferase YP_001282842.1 1719170 D 419947 CDS YP_001282843.1 148661320 5214217 1720243..1721487 1 NC_009525.1 glycosyl transferase 1721487 5214217 MRA_1536 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001282843.1 1720243 D 419947 CDS YP_001282844.1 148661321 5213743 1721534..1722319 1 NC_009525.1 rhamnosyl transferase WbbL2 1722319 wbbL2 5213743 wbbL2 Mycobacterium tuberculosis H37Ra rhamnosyl transferase WbbL2 YP_001282844.1 1721534 D 419947 CDS YP_001282845.1 148661322 5213744 complement(1722297..1723577) 1 NC_009525.1 glycosyl transferase 1723577 5213744 MRA_1538 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001282845.1 1722297 R 419947 CDS YP_001282846.1 148661323 5213745 complement(1723600..1729926) 1 NC_009525.1 polyketide synthase pks5 1729926 pks5 5213745 pks5 Mycobacterium tuberculosis H37Ra polyketide synthase pks5 YP_001282846.1 1723600 R 419947 CDS YP_001282847.1 148661324 5213746 complement(1730470..1730967) 1 NC_009525.1 polyketide synthase associated protein PapA4 1730967 papA4 5213746 papA4 Mycobacterium tuberculosis H37Ra polyketide synthase associated protein PapA4 YP_001282847.1 1730470 R 419947 CDS YP_001282848.1 148661325 5213747 1731019..1732773 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1732773 fadD24 5213747 fadD24 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001282848.1 1731019 D 419947 CDS YP_001282849.1 148661326 5213748 1732890..1733993 1 NC_009525.1 alcohol dehydrogenase 1733993 adh 5213748 adh Mycobacterium tuberculosis H37Ra alcohol dehydrogenase YP_001282849.1 1732890 D 419947 CDS YP_001282850.1 148661327 5213749 1733990..1734556 1 NC_009525.1 hypothetical protein 1734556 5213749 MRA_1543 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282850.1 1733990 D 419947 CDS YP_001282851.1 148661328 5213750 complement(1734633..1735067) 1 NC_009525.1 hypothetical protein 1735067 5213750 MRA_1544 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282851.1 1734633 R 419947 CDS YP_001282852.1 148661329 5214885 1735127..1736254 1 NC_009525.1 hypothetical protein 1736254 5214885 MRA_1545 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282852.1 1735127 D 419947 CDS YP_001282853.1 148661330 5214886 1736251..1736928 1 NC_009525.1 transcriptional regulator 1736928 5214886 MRA_1546 Mycobacterium tuberculosis H37Ra transcriptional regulator YP_001282853.1 1736251 D 419947 CDS YP_001282854.1 148661331 5214887 1737493..1737729 1 NC_009525.1 hypothetical protein 1737729 5214887 MRA_1547 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282854.1 1737493 D 419947 CDS YP_001282855.1 148661332 5214888 1738036..1741161 1 NC_009525.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 1741161 ileS 5214888 ileS Mycobacterium tuberculosis H37Ra isoleucyl-tRNA synthetase YP_001282855.1 1738036 D 419947 CDS YP_001282856.1 148661333 5214889 1741373..1742764 1 NC_009525.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1742764 dinX 5214889 dinX Mycobacterium tuberculosis H37Ra DNA polymerase IV YP_001282856.1 1741373 D 419947 CDS YP_001282857.1 148661334 5214890 complement(1742729..1743709) 1 NC_009525.1 L-asparaginase 1743709 ansA 5214890 ansA Mycobacterium tuberculosis H37Ra L-asparaginase YP_001282857.1 1742729 R 419947 CDS YP_001282858.1 148661335 5214891 1743761..1744369 1 NC_009525.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1744369 lspA 5214891 lspA Mycobacterium tuberculosis H37Ra lipoprotein signal peptidase YP_001282858.1 1743761 D 419947 CDS YP_001282859.1 148661336 5214892 1744362..1745288 1 NC_009525.1 pseudouridine synthase 1745288 5214892 MRA_1552 Mycobacterium tuberculosis H37Ra pseudouridine synthase YP_001282859.1 1744362 D 419947 CDS YP_001282860.1 148661337 5215284 complement(1745295..1745888) 1 NC_009525.1 lipoprotein LprI 1745888 lprI 5215284 lprI Mycobacterium tuberculosis H37Ra lipoprotein LprI YP_001282860.1 1745295 R 419947 CDS YP_001282861.1 148661338 5215285 complement(1745943..1746353) 1 NC_009525.1 hypothetical protein 1746353 glbN 5215285 glbN Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282861.1 1745943 R 419947 CDS YP_001282862.1 148661339 5215286 1746581..1747606 1 NC_009525.1 fatty acyl-CoA reductase 1747606 5215286 MRA_1555 Mycobacterium tuberculosis H37Ra fatty acyl-CoA reductase YP_001282862.1 1746581 D 419947 CDS YP_001282863.1 148661340 5215287 1747611..1748414 1 NC_009525.1 short-chain type dehydrogenase/reductase 1748414 5215287 MRA_1556 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001282863.1 1747611 D 419947 CDS YP_001282864.1 148661341 5215288 1748436..1748663 1 NC_009525.1 hypothetical protein 1748663 5215288 MRA_1557 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282864.1 1748436 D 419947 CDS YP_001282865.1 148661342 5215289 1748712..1749143 1 NC_009525.1 hypothetical protein 1749143 5215289 MRA_1558 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282865.1 1748712 D 419947 CDS YP_001282866.1 148661343 5215290 1749211..1752765 1 NC_009525.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1752765 dnaE 5215290 dnaE Mycobacterium tuberculosis H37Ra DNA polymerase III subunit alpha YP_001282866.1 1749211 D 419947 CDS YP_001282867.1 148661344 5215291 complement(1752814..1754850) 1 NC_009525.1 PPE family protein 1754850 5215291 MRA_1560 Mycobacterium tuberculosis H37Ra PPE family protein YP_001282867.1 1752814 R 419947 CDS YP_001282868.1 148661345 5212475 1755027..1755554 1 NC_009525.1 fatty-acid--CoA ligase 1755554 fadD11.1 5212475 fadD11.1 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001282868.1 1755027 D 419947 CDS YP_001282869.1 148661346 5212476 1755233..1756948 1 NC_009525.1 fatty-acid--CoA ligase 1756948 fadD11 5212476 fadD11 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001282869.1 1755233 D 419947 CDS YP_001282870.1 148661347 5212477 1756962..1758827 1 NC_009525.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 1758827 plsB1 5212477 plsB1 Mycobacterium tuberculosis H37Ra glycerol-3-phosphate acyltransferase YP_001282870.1 1756962 D 419947 CDS YP_001282871.1 148661348 5212478 1759198..1760949 1 NC_009525.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 1760949 frdA 5212478 frdA Mycobacterium tuberculosis H37Ra fumarate reductase flavoprotein subunit YP_001282871.1 1759198 D 419947 CDS YP_001282872.1 148661349 5212479 1760952..1761695 1 NC_009525.1 fumarate reductase iron-sulfur subunit FrdB 1761695 frdB 5212479 frdB Mycobacterium tuberculosis H37Ra fumarate reductase iron-sulfur subunit FrdB YP_001282872.1 1760952 D 419947 CDS YP_001282873.1 148661350 5212480 1761692..1762072 1 NC_009525.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 1762072 frdC 5212480 frdC Mycobacterium tuberculosis H37Ra fumarate reductase subunit C YP_001282873.1 1761692 D 419947 CDS YP_001282874.1 148661351 5212481 1762069..1762446 1 NC_009525.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 1762446 frdD 5212481 frdD Mycobacterium tuberculosis H37Ra fumarate reductase subunit D YP_001282874.1 1762069 D 419947 CDS YP_001282875.1 148661352 5213880 1762514..1763122 1 NC_009525.1 regulatory protein 1763122 5213880 MRA_1568 Mycobacterium tuberculosis H37Ra regulatory protein YP_001282875.1 1762514 D 419947 CDS YP_001282876.1 148661353 5213881 1763261..1764454 1 NC_009525.1 transmembrane transport protein MmpL6 1764454 mmpL6 5213881 mmpL6 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL6 YP_001282876.1 1763261 D 419947 CDS YP_001282877.1 148661354 5213882 1764464..1764910 1 NC_009525.1 hypothetical protein 1764910 5213882 MRA_1570 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282877.1 1764464 D 419947 CDS YP_001282878.1 148661355 5213883 1764945..1766234 1 NC_009525.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1766234 ilvA 5213883 ilvA Mycobacterium tuberculosis H37Ra threonine dehydratase YP_001282878.1 1764945 D 419947 CDS YP_001282879.1 148661356 5213884 1766272..1766490 1 NC_009525.1 hypothetical protein 1766490 5213884 MRA_1572 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282879.1 1766272 D 419947 CDS YP_001282880.1 148661357 5213885 1766496..1766900 1 NC_009525.1 hypothetical protein 1766900 5213885 MRA_1573 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282880.1 1766496 D 419947 CDS YP_001282881.1 148661358 5213886 complement(1766917..1768659) 1 NC_009525.1 maltooligosyl trehalose trehalohydrolase 1768659 treZ 5213886 treZ Mycobacterium tuberculosis H37Ra maltooligosyl trehalose trehalohydrolase YP_001282881.1 1766917 R 419947 CDS YP_001282882.1 148661359 5213887 complement(1768652..1770949) 1 NC_009525.1 maltooligosyl trehalose synthase 1770949 treY 5213887 treY Mycobacterium tuberculosis H37Ra maltooligosyl trehalose synthase YP_001282882.1 1768652 R 419947 CDS YP_001282883.1 148661360 5212410 complement(1770953..1773118) 1 NC_009525.1 glycogen operon protein 1773118 treX 5212410 treX Mycobacterium tuberculosis H37Ra glycogen operon protein YP_001282883.1 1770953 R 419947 CDS YP_001282884.1 148661361 5212411 complement(1773157..1775346) 1 NC_009525.1 lipopolysaccharide biosynthesis protein WbpC 1775346 5212411 MRA_1577 Mycobacterium tuberculosis H37Ra lipopolysaccharide biosynthesis protein WbpC YP_001282884.1 1773157 R 419947 CDS YP_001282885.1 148661362 5212412 complement(1775445..1776137) 1 NC_009525.1 inv protein 1776137 5212412 MRA_1578 Mycobacterium tuberculosis H37Ra inv protein YP_001282885.1 1775445 R 419947 CDS YP_001282886.1 148661363 5212413 complement(1776377..1776661) 1 NC_009525.1 hypothetical protein 1776661 5212413 MRA_1579 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282886.1 1776377 R 419947 CDS YP_001282887.1 148661364 5212414 1776909..1778222 1 NC_009525.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1778222 bioA 5212414 bioA Mycobacterium tuberculosis H37Ra adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001282887.1 1776909 D 419947 CDS YP_001282888.1 148661365 5212415 1778219..1779379 1 NC_009525.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1779379 bioF1 5212415 bioF1 Mycobacterium tuberculosis H37Ra 8-amino-7-oxononanoate synthase YP_001282888.1 1778219 D 419947 CDS YP_001282889.1 148661366 5212416 1779376..1780056 1 NC_009525.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1780056 bioD 5212416 bioD Mycobacterium tuberculosis H37Ra dithiobiotin synthetase YP_001282889.1 1779376 D 419947 CDS YP_001282890.1 148661367 5212417 1780056..1780565 1 NC_009525.1 hypothetical protein 1780565 5212417 MRA_1583 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282890.1 1780056 D 419947 CDS YP_001282891.1 148661368 5213201 1780831..1781241 1 NC_009525.1 phiRv1 phage protein 1781241 5213201 MRA_1584 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282891.1 1780831 D 419947 CDS YP_001282892.1 148661369 5213202 1781447..1781758 1 NC_009525.1 hypothetical protein 1781758 5213202 MRA_1585 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282892.1 1781447 D 419947 CDS YP_001282893.1 148661370 5213203 1781716..1782171 1 NC_009525.1 phiRv1 phage protein 1782171 5213203 MRA_1586 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282893.1 1781716 D 419947 CDS YP_001282894.1 148661371 5213204 complement(1782161..1783582) 1 NC_009525.1 phiRv1 phage protein 1783582 5213204 MRA_1587 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282894.1 1782161 R 419947 CDS YP_001282895.1 148661372 5213205 complement(1783590..1784102) 1 NC_009525.1 phiRv1 phage protein 1784102 5213205 MRA_1588 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282895.1 1783590 R 419947 CDS YP_001282896.1 148661373 5213206 complement(1784276..1784746) 1 NC_009525.1 hypothetical protein 1784746 5213206 MRA_1589 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282896.1 1784276 R 419947 CDS YP_001282897.1 148661374 5213207 complement(1784827..1785141) 1 NC_009525.1 phiRv1 phage protein 1785141 5213207 MRA_1590 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282897.1 1784827 R 419947 CDS YP_001282898.1 148661375 5213208 complement(1785138..1785410) 1 NC_009525.1 phiRv1 phage protein 1785410 5213208 MRA_1591 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282898.1 1785138 R 419947 CDS YP_001282899.1 148661376 5213921 complement(1785424..1785819) 1 NC_009525.1 phiRv1 phage protein 1785819 5213921 MRA_1592 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282899.1 1785424 R 419947 CDS YP_001282900.1 148661377 5213922 complement(1786015..1787430) 1 NC_009525.1 phiRv1 phage protein 1787430 5213922 MRA_1593 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282900.1 1786015 R 419947 CDS YP_001282901.1 148661378 5213923 complement(1787430..1787828) 1 NC_009525.1 phiRv1 phage protein 1787828 5213923 MRA_1594 Mycobacterium tuberculosis H37Ra phiRv1 phage protein YP_001282901.1 1787430 R 419947 CDS YP_001282902.1 148661379 5213924 complement(1787825..1788046) 1 NC_009525.1 phiRv1 prophage protein 1788046 5213924 MRA_1595 Mycobacterium tuberculosis H37Ra phiRv1 prophage protein YP_001282902.1 1787825 R 419947 CDS YP_001282903.1 148661380 5213925 complement(1788102..1788617) 1 NC_009525.1 phiRv1 prophage protein 1788617 5213925 MRA_1596 Mycobacterium tuberculosis H37Ra phiRv1 prophage protein YP_001282903.1 1788102 R 419947 CDS YP_001282904.1 148661381 5213926 complement(1788614..1790023) 1 NC_009525.1 integrase 1790023 5213926 MRA_1597 Mycobacterium tuberculosis H37Ra integrase YP_001282904.1 1788614 R 419947 CDS YP_001282905.1 148661382 5213927 complement(1789680..1790681) 1 NC_009525.1 REP13E12 repeat-containing protein 1790681 5213927 MRA_1598 Mycobacterium tuberculosis H37Ra REP13E12 repeat-containing protein YP_001282905.1 1789680 R 419947 CDS YP_001282906.1 148661383 5213629 complement(1790686..1791354) 1 NC_009525.1 REP13E12 repeat-containing protein 1791354 5213629 MRA_1598A Mycobacterium tuberculosis H37Ra REP13E12 repeat-containing protein YP_001282906.1 1790686 R 419947 CDS YP_001282907.1 148661384 5213630 1791802..1792851 1 NC_009525.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase 1792851 bioB 5213630 bioB Mycobacterium tuberculosis H37Ra biotin synthase YP_001282907.1 1791802 D 419947 CDS YP_001282908.1 148661385 5213631 1792852..1793091 1 NC_009525.1 hypothetical protein 1793091 5213631 MRA_1600 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282908.1 1792852 D 419947 CDS YP_001282909.1 148661386 5213632 1793088..1793753 1 NC_009525.1 transmembrane protein 1793753 5213632 MRA_1601 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282909.1 1793088 D 419947 CDS YP_001282910.1 148661387 5213633 complement(1793918..1795258) 1 NC_009525.1 hypothetical protein 1795258 5213633 MRA_1602 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282910.1 1793918 R 419947 CDS YP_001282911.1 148661388 5213634 complement(1795515..1796225) 1 NC_009525.1 hypothetical protein 1796225 5213634 MRA_1603 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282911.1 1795515 R 419947 CDS YP_001282912.1 148661389 5213635 1796274..1797323 1 NC_009525.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1797323 nadA 5213635 nadA Mycobacterium tuberculosis H37Ra quinolinate synthetase YP_001282912.1 1796274 D 419947 CDS YP_001282913.1 148661390 5213636 1797323..1798906 1 NC_009525.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 1798906 nadB 5213636 nadB Mycobacterium tuberculosis H37Ra L-aspartate oxidase YP_001282913.1 1797323 D 419947 CDS YP_001282914.1 148661391 5211619 1798906..1799763 1 NC_009525.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1799763 nadC 5211619 nadC Mycobacterium tuberculosis H37Ra nicotinate-nucleotide pyrophosphorylase YP_001282914.1 1798906 D 419947 CDS YP_001282915.1 148661392 5211620 1799812..1800570 1 NC_009525.1 hypothetical protein 1800570 5211620 MRA_1607 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282915.1 1799812 D 419947 CDS YP_001282916.1 148661393 5211621 complement(1800591..1801001) 1 NC_009525.1 hypothetical protein 1801001 5211621 MRA_1608 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282916.1 1800591 R 419947 CDS YP_001282917.1 148661394 5211622 1801101..1802417 1 NC_009525.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1802417 hisD 5211622 hisD Mycobacterium tuberculosis H37Ra histidinol dehydrogenase YP_001282917.1 1801101 D 419947 CDS YP_001282918.1 148661395 5211623 1802414..1803556 1 NC_009525.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1803556 hisC1 5211623 hisC1 Mycobacterium tuberculosis H37Ra histidinol-phosphate aminotransferase YP_001282918.1 1802414 D 419947 CDS YP_001282919.1 148661396 5211624 1803553..1804185 1 NC_009525.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1804185 hisB 5211624 hisB Mycobacterium tuberculosis H37Ra imidazoleglycerol-phosphate dehydratase YP_001282919.1 1803553 D 419947 CDS YP_001282920.1 148661397 5211625 1804182..1804802 1 NC_009525.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1804802 hisH 5211625 hisH Mycobacterium tuberculosis H37Ra imidazole glycerol phosphate synthase subunit HisH YP_001282920.1 1804182 D 419947 CDS YP_001282921.1 148661398 5211626 1804812..1805549 1 NC_009525.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A 1805549 hisA 5211626 hisA Mycobacterium tuberculosis H37Ra phosphoribosyl isomerase A YP_001282921.1 1804812 D 419947 CDS YP_001282922.1 148661399 5215369 1805557..1806369 1 NC_009525.1 inositol-monophosphatase ImpA 1806369 impA 5215369 impA Mycobacterium tuberculosis H37Ra inositol-monophosphatase ImpA YP_001282922.1 1805557 D 419947 CDS YP_001282923.1 148661400 5215370 1806371..1807174 1 NC_009525.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1807174 hisF 5215370 hisF Mycobacterium tuberculosis H37Ra imidazole glycerol phosphate synthase subunit HisF YP_001282923.1 1806371 D 419947 CDS YP_001282924.1 148661401 5215371 1807171..1807518 1 NC_009525.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 1807518 hisI 5215371 hisI Mycobacterium tuberculosis H37Ra phosphoribosyl-AMP cyclohydrolase YP_001282924.1 1807171 D 419947 CDS YP_001282925.1 148661402 5215372 1807699..1808781 1 NC_009525.1 cation/proton antiporter 1808781 chaA 5215372 chaA Mycobacterium tuberculosis H37Ra cation/proton antiporter YP_001282925.1 1807699 D 419947 CDS YP_001282926.1 148661403 5215373 complement(1808816..1809280) 1 NC_009525.1 peroxidoxin BcpB 1809280 bcpB 5215373 bcpB Mycobacterium tuberculosis H37Ra peroxidoxin BcpB YP_001282926.1 1808816 R 419947 CDS YP_001282927.1 148661404 5215374 1809421..1810971 1 NC_009525.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1810971 trpE 5215374 trpE Mycobacterium tuberculosis H37Ra anthranilate synthase component I YP_001282927.1 1809421 D 419947 CDS YP_001282928.1 148661405 5215375 1810961..1811668 1 NC_009525.1 hypothetical protein 1811668 5215375 MRA_1620 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282928.1 1810961 D 419947 CDS YP_001282929.1 148661406 5215376 1811758..1812576 1 NC_009525.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 1812576 trpC 5215376 trpC Mycobacterium tuberculosis H37Ra indole-3-glycerol phosphate synthase YP_001282929.1 1811758 D 419947 CDS YP_001282930.1 148661407 5215163 1812645..1813877 1 NC_009525.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1813877 trpB 5215163 trpB Mycobacterium tuberculosis H37Ra tryptophan synthase subunit beta YP_001282930.1 1812645 D 419947 CDS YP_001282931.1 148661408 5215164 1813877..1814689 1 NC_009525.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1814689 trpA 5215164 trpA Mycobacterium tuberculosis H37Ra tryptophan synthase subunit alpha YP_001282931.1 1813877 D 419947 CDS YP_001282932.1 148661409 5215165 1814689..1816095 1 NC_009525.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1816095 lgt 5215165 lgt Mycobacterium tuberculosis H37Ra prolipoprotein diacylglyceryl transferase YP_001282932.1 1814689 D 419947 CDS YP_001282933.1 148661410 5215166 1816771..1817211 1 NC_009525.1 hypothetical protein 1817211 5215166 MRA_1625 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282933.1 1816771 D 419947 CDS YP_001282934.1 148661411 5215167 1817201..1817599 1 NC_009525.1 hypothetical protein 1817599 5215167 MRA_1626 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282934.1 1817201 D 419947 CDS YP_001282935.1 148661412 5215168 1817707..1819125 1 NC_009525.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1819125 pykA 5215168 pykA Mycobacterium tuberculosis H37Ra pyruvate kinase YP_001282935.1 1817707 D 419947 CDS YP_001282936.1 148661413 5215169 1819133..1820035 1 NC_009525.1 acyl-CoA thioesterase 1820035 tesB1 5215169 tesB1 Mycobacterium tuberculosis H37Ra acyl-CoA thioesterase YP_001282936.1 1819133 D 419947 CDS YP_001282937.1 148661414 5214877 1820093..1821547 1 NC_009525.1 hypothetical protein 1821547 5214877 MRA_1629 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282937.1 1820093 D 419947 CDS YP_001282938.1 148661415 5214878 complement(1821481..1823211) 1 NC_009525.1 component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC 1823211 cydC 5214878 cydC Mycobacterium tuberculosis H37Ra component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC YP_001282938.1 1821481 R 419947 CDS YP_001282939.1 148661416 5214879 complement(1823208..1824791) 1 NC_009525.1 component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydD 1824791 cydD 5214879 cydD Mycobacterium tuberculosis H37Ra component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydD YP_001282939.1 1823208 R 419947 CDS YP_001282940.1 148661417 5214880 complement(1824878..1825918) 1 NC_009525.1 cytochrome d ubiquinol oxidase subunit II 1825918 cydB 5214880 cydB Mycobacterium tuberculosis H37Ra cytochrome d ubiquinol oxidase subunit II YP_001282940.1 1824878 R 419947 CDS YP_001282941.1 148661418 5214881 complement(1825948..1827405) 1 NC_009525.1 cytochrome d ubiquinol oxidase subunit I 1827405 cydA 5214881 cydA Mycobacterium tuberculosis H37Ra cytochrome d ubiquinol oxidase subunit I YP_001282941.1 1825948 R 419947 CDS YP_001282942.1 148661419 5214882 complement(1827516..1828103) 1 NC_009525.1 hypothetical protein 1828103 5214882 MRA_1634 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282942.1 1827516 R 419947 CDS YP_001282943.1 148661420 5214883 complement(1828132..1829463) 1 NC_009525.1 membrane-anchored adenylyl cyclase Cya 1829463 cya 5214883 cya Mycobacterium tuberculosis H37Ra membrane-anchored adenylyl cyclase Cya YP_001282943.1 1828132 R 419947 CDS YP_001282944.1 148661421 5213801 1829698..1830315 1 NC_009525.1 two-component system transcriptional regulator 1830315 5213801 MRA_1636 Mycobacterium tuberculosis H37Ra two-component system transcriptional regulator YP_001282944.1 1829698 D 419947 CDS YP_001282945.1 148661422 5213802 complement(1830383..1831591) 1 NC_009525.1 lipid-transfer protein 1831591 5213802 MRA_1637 Mycobacterium tuberculosis H37Ra lipid-transfer protein YP_001282945.1 1830383 R 419947 CDS YP_001282946.1 148661423 5213803 complement(1831588..1832079) 1 NC_009525.1 hypothetical protein 1832079 5213803 MRA_1638 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282946.1 1831588 R 419947 CDS YP_001282947.1 148661424 5213804 1832183..1834897 1 NC_009525.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1834897 polA 5213804 polA Mycobacterium tuberculosis H37Ra DNA polymerase I YP_001282947.1 1832183 D 419947 CDS YP_001282948.1 148661425 5213805 1835060..1836505 1 NC_009525.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1836505 rpsA 5213805 rpsA Mycobacterium tuberculosis H37Ra 30S ribosomal protein S1 YP_001282948.1 1835060 D 419947 CDS YP_001282949.1 148661426 5213806 1836531..1837754 1 NC_009525.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain; dephospho-CoA kinase/protein folding accessory domain-containing protein 1837754 coaE 5213806 coaE Mycobacterium tuberculosis H37Ra dephospho-CoA kinase/protein folding accessory domain-containing protein YP_001282949.1 1836531 D 419947 CDS YP_001282950.1 148661427 5213807 complement(1837905..1838348) 1 NC_009525.1 hypothetical protein 1838348 5213807 MRA_1642 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282950.1 1837905 R 419947 CDS YP_001282951.1 148661428 5212601 1838593..1840689 1 NC_009525.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1840689 uvrB 5212601 uvrB Mycobacterium tuberculosis H37Ra excinuclease ABC subunit B YP_001282951.1 1838593 D 419947 CDS YP_001282952.1 148661429 5212602 1840686..1842101 1 NC_009525.1 drug transporter 1842101 5212602 MRA_1644 Mycobacterium tuberculosis H37Ra drug transporter YP_001282952.1 1840686 D 419947 CDS YP_001282953.1 148661430 5212603 complement(1842090..1843760) 1 NC_009525.1 transmembrane protein 1843760 5212603 MRA_1645 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282953.1 1842090 R 419947 CDS YP_001282954.1 148661431 5212604 1843969..1844409 1 NC_009525.1 hypothetical protein 1844409 5212604 MRA_1646 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282954.1 1843969 D 419947 CDS YP_001282955.1 148661432 5212605 complement(1844416..1845210) 1 NC_009525.1 hypothetical protein 1845210 5212605 MRA_1647 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282955.1 1844416 R 419947 CDS YP_001282956.1 148661433 5212606 1845259..1848177 1 NC_009525.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1848177 uvrA 5212606 uvrA Mycobacterium tuberculosis H37Ra excinuclease ABC subunit A YP_001282956.1 1845259 D 419947 CDS YP_001282957.1 148661434 5212607 complement(1848234..1848491) 1 NC_009525.1 hypothetical protein 1848491 5212607 MRA_1649 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282957.1 1848234 R 419947 CDS YP_001282958.1 148661435 5212608 complement(1848507..1849976) 1 NC_009525.1 hypothetical protein 1849976 5212608 MRA_1650 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282958.1 1848507 R 419947 CDS YP_001282959.1 148661436 5214401 complement(1850035..1853553) 1 NC_009525.1 catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 1853553 lysS 5214401 lysS Mycobacterium tuberculosis H37Ra lysyl-tRNA synthetase YP_001282959.1 1850035 R 419947 CDS YP_001282960.1 148661437 5214402 1853728..1854396 1 NC_009525.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1854396 infC 5214402 infC Mycobacterium tuberculosis H37Ra translation initiation factor IF-3 YP_001282960.1 1853728 D 419947 CDS YP_001282961.1 148661438 5214403 1854446..1854640 1 NC_009525.1 50S ribosomal protein L35 1854640 rpmI 5214403 rpmI Mycobacterium tuberculosis H37Ra 50S ribosomal protein L35 YP_001282961.1 1854446 D 419947 CDS YP_001282962.1 148661439 5214404 1854702..1855091 1 NC_009525.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1855091 rplT 5214404 rplT Mycobacterium tuberculosis H37Ra 50S ribosomal protein L20 YP_001282962.1 1854702 D 419947 CDS YP_001282963.1 148661440 5214405 1855124..1855906 1 NC_009525.1 23S rRNA methyltransferase TsnR 1855906 tsnR 5214405 tsnR Mycobacterium tuberculosis H37Ra 23S rRNA methyltransferase TsnR YP_001282963.1 1855124 D 419947 CDS YP_001282964.1 148661441 5214406 complement(1855917..1856972) 1 NC_009525.1 hypothetical protein 1856972 5214406 MRA_1656 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282964.1 1855917 R 419947 CDS YP_001282965.1 148661442 5214407 1857282..1858214 1 NC_009525.1 PE family protein 1858214 5214407 MRA_1657 Mycobacterium tuberculosis H37Ra PE family protein YP_001282965.1 1857282 D 419947 CDS YP_001282966.1 148661443 5215193 1858292..1859242 1 NC_009525.1 hypothetical protein 1859242 5215193 MRA_1658 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282966.1 1858292 D 419947 CDS YP_001282967.1 148661444 5215194 1859249..1860055 1 NC_009525.1 transmembrane protein 1860055 5215194 MRA_1659 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001282967.1 1859249 D 419947 CDS YP_001282968.1 148661445 5215195 1860251..1861276 1 NC_009525.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1861276 pheS 5215195 pheS Mycobacterium tuberculosis H37Ra phenylalanyl-tRNA synthetase subunit alpha YP_001282968.1 1860251 D 419947 CDS YP_001282969.1 148661446 5215196 1861276..1863771 1 NC_009525.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1863771 pheT 5215196 pheT Mycobacterium tuberculosis H37Ra phenylalanyl-tRNA synthetase subunit beta YP_001282969.1 1861276 D 419947 CDS YP_001282970.1 148661447 5215197 complement(1863865..1866900) 1 NC_009525.1 PE-PGRS family protein 1866900 5215197 MRA_1662 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001282970.1 1863865 R 419947 CDS YP_001282971.1 148661448 5215198 1867094..1868152 1 NC_009525.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 1868152 argC 5215198 argC Mycobacterium tuberculosis H37Ra N-acetyl-gamma-glutamyl-phosphate reductase YP_001282971.1 1867094 D 419947 CDS YP_001282972.1 148661449 5215199 1868149..1869363 1 NC_009525.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 1869363 argJ 5215199 argJ Mycobacterium tuberculosis H37Ra bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_001282972.1 1868149 D 419947 CDS YP_001282973.1 148661450 5215200 1869360..1870244 1 NC_009525.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1870244 argB 5215200 argB Mycobacterium tuberculosis H37Ra acetylglutamate kinase YP_001282973.1 1869360 D 419947 CDS YP_001282974.1 148661451 5215521 1870241..1871443 1 NC_009525.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 1871443 argD 5215521 argD Mycobacterium tuberculosis H37Ra acetylornithine aminotransferase YP_001282974.1 1870241 D 419947 CDS YP_001282975.1 148661452 5215522 1871440..1872363 1 NC_009525.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1872363 argF 5215522 argF Mycobacterium tuberculosis H37Ra ornithine carbamoyltransferase YP_001282975.1 1871440 D 419947 CDS YP_001282976.1 148661453 5215523 1872360..1872872 1 NC_009525.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 1872872 argR 5215523 argR Mycobacterium tuberculosis H37Ra arginine repressor ArgR YP_001282976.1 1872360 D 419947 CDS YP_001282977.1 148661454 5215524 1872881..1874077 1 NC_009525.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 1874077 argG 5215524 argG Mycobacterium tuberculosis H37Ra argininosuccinate synthase YP_001282977.1 1872881 D 419947 CDS YP_001282978.1 148661455 5215525 1874157..1875569 1 NC_009525.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1875569 argH 5215525 argH Mycobacterium tuberculosis H37Ra argininosuccinate lyase YP_001282978.1 1874157 D 419947 CDS YP_001282979.1 148661456 5215526 1875678..1876739 1 NC_009525.1 chalcone synthase Pks10 1876739 pks10 5215526 pks10 Mycobacterium tuberculosis H37Ra chalcone synthase Pks10 YP_001282979.1 1875678 D 419947 CDS YP_001282980.1 148661457 5215527 1876822..1883202 1 NC_009525.1 polyketide synthase Pks7 1883202 pks7 5215527 pks7 Mycobacterium tuberculosis H37Ra polyketide synthase Pks7 YP_001282980.1 1876822 D 419947 CDS YP_001282981.1 148661458 5215528 1883222..1888030 1 NC_009525.1 polyketide synthase Pks8 1888030 pks8 5215528 pks8 Mycobacterium tuberculosis H37Ra polyketide synthase Pks8 YP_001282981.1 1883222 D 419947 CDS YP_001282982.1 148661459 5212001 1888030..1889538 1 NC_009525.1 polyketide synthase Pks17 1889538 pks17 5212001 pks17 Mycobacterium tuberculosis H37Ra polyketide synthase Pks17 YP_001282982.1 1888030 D 419947 CDS YP_001282983.1 148661460 5212002 1889544..1892597 1 NC_009525.1 polyketide synthase Pks9 1892597 pks9 5212002 pks9 Mycobacterium tuberculosis H37Ra polyketide synthase Pks9 YP_001282983.1 1889544 D 419947 CDS YP_001282984.1 148661461 5212003 1892744..1893805 1 NC_009525.1 chalcone synthase Pks11 1893805 pks11 5212003 pks11 Mycobacterium tuberculosis H37Ra chalcone synthase Pks11 YP_001282984.1 1892744 D 419947 CDS YP_001282985.1 148661462 5212004 complement(1893788..1895080) 1 NC_009525.1 cytochrome P450 139 CYP139 1895080 cyp139 5212004 cyp139 Mycobacterium tuberculosis H37Ra cytochrome P450 139 CYP139 YP_001282985.1 1893788 R 419947 CDS YP_001282986.1 148661463 5212005 complement(1895095..1895748) 1 NC_009525.1 macrolide ABC transporter ATP-binding protein 1895748 5212005 MRA_1678 Mycobacterium tuberculosis H37Ra macrolide ABC transporter ATP-binding protein YP_001282986.1 1895095 R 419947 CDS YP_001282987.1 148661464 5212006 complement(1895742..1896860) 1 NC_009525.1 macrolide ABC transporter ATP-binding protein 1896860 5212006 MRA_1679 Mycobacterium tuberculosis H37Ra macrolide ABC transporter ATP-binding protein YP_001282987.1 1895742 R 419947 CDS YP_001282988.1 148661465 5212007 1897243..1897605 1 NC_009525.1 hypothetical protein 1897605 5212007 MRA_1679A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282988.1 1897243 D 419947 CDS YP_001282989.1 148661466 5212008 1897638..1897985 1 NC_009525.1 hypothetical protein 1897985 5212008 MRA_1680 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282989.1 1897638 D 419947 CDS YP_001282990.1 148661467 5212625 1897993..1898385 1 NC_009525.1 hypothetical protein 1898385 5212625 MRA_1681 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282990.1 1897993 D 419947 CDS YP_001282991.1 148661468 5212626 complement(1898394..1899725) 1 NC_009525.1 phthalate permease 1899725 5212626 MRA_1682 Mycobacterium tuberculosis H37Ra phthalate permease YP_001282991.1 1898394 R 419947 CDS YP_001282992.1 148661469 5212627 complement(1899818..1900750) 1 NC_009525.1 hypothetical protein 1900750 5212627 MRA_1683 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282992.1 1899818 R 419947 CDS YP_001282993.1 148661470 5212628 complement(1900778..1901434) 1 NC_009525.1 transcription regulator ArsR 1901434 5212628 MRA_1684 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001282993.1 1900778 R 419947 CDS YP_001282994.1 148661471 5212629 1901490..1901765 1 NC_009525.1 hypothetical protein 1901765 5212629 MRA_1685 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282994.1 1901490 D 419947 CDS YP_001282995.1 148661472 5212630 complement(1901759..1902493) 1 NC_009525.1 Crp/Fnr family transcriptional regulator 1902493 5212630 MRA_1686 Mycobacterium tuberculosis H37Ra Crp/Fnr family transcriptional regulator YP_001282995.1 1901759 R 419947 CDS YP_001282996.1 148661473 5212631 1902565..1903269 1 NC_009525.1 hypothetical protein 1903269 5212631 MRA_1687 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282996.1 1902565 D 419947 CDS YP_001282997.1 148661474 5212632 1903266..1903814 1 NC_009525.1 lipoprotein DsbF 1903814 dsbF 5212632 dsbF Mycobacterium tuberculosis H37Ra lipoprotein DsbF YP_001282997.1 1903266 D 419947 CDS YP_001282998.1 148661475 5213533 1903915..1904817 1 NC_009525.1 hypothetical protein 1904817 5213533 MRA_1689 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001282998.1 1903915 D 419947 CDS YP_001282999.1 148661476 5213534 1904817..1905938 1 NC_009525.1 acyl-CoA dehydrogenase 1905938 fadE16 5213534 fadE16 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001282999.1 1904817 D 419947 CDS YP_001283000.1 148661477 5213535 1905947..1906771 1 NC_009525.1 hypothetical protein 1906771 5213535 MRA_1691 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283000.1 1905947 D 419947 CDS YP_001283001.1 148661478 5213536 1906768..1907760 1 NC_009525.1 molybdopterin biosynthesis protein MoeX 1907760 moeX 5213536 moeX Mycobacterium tuberculosis H37Ra molybdopterin biosynthesis protein MoeX YP_001283001.1 1906768 D 419947 CDS YP_001283002.1 148661479 5213537 1907921..1908838 1 NC_009525.1 hypothetical protein 1908838 5213537 MRA_1693 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283002.1 1907921 D 419947 CDS YP_001283003.1 148661480 5213538 1909112..1912111 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1912111 5213538 MRA_1694 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001283003.1 1909112 D 419947 CDS YP_001283004.1 148661481 5213539 1912104..1912328 1 NC_009525.1 hypothetical protein 1912328 5213539 MRA_1694A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283004.1 1912104 D 419947 CDS YP_001283005.1 148661482 5213540 complement(1912294..1912917) 1 NC_009525.1 hypothetical protein 1912917 5213540 MRA_1695 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283005.1 1912294 R 419947 CDS YP_001283006.1 148661483 5214282 complement(1912919..1913599) 1 NC_009525.1 multidrug resistance ABC transporter permease 1913599 5214282 MRA_1696 Mycobacterium tuberculosis H37Ra multidrug resistance ABC transporter permease YP_001283006.1 1912919 R 419947 CDS YP_001283007.1 148661484 5214283 complement(1913671..1914438) 1 NC_009525.1 multidrug resistance ABC transporter ATP-binding protein 1914438 5214283 MRA_1697 Mycobacterium tuberculosis H37Ra multidrug resistance ABC transporter ATP-binding protein YP_001283007.1 1913671 R 419947 CDS YP_001283008.1 148661485 5214284 1914497..1915108 1 NC_009525.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 1915108 mpg 5214284 mpg Mycobacterium tuberculosis H37Ra 3-methyladenine DNA glycosylase YP_001283008.1 1914497 D 419947 CDS YP_001283009.1 148661486 5214285 1915120..1916394 1 NC_009525.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1916394 tyrS 5214285 tyrS Mycobacterium tuberculosis H37Ra tyrosyl-tRNA synthetase YP_001283009.1 1915120 D 419947 CDS YP_001283010.1 148661487 5214286 1917045..1917428 1 NC_009525.1 lipoprotein LprJ 1917428 lprJ 5214286 lprJ Mycobacterium tuberculosis H37Ra lipoprotein LprJ YP_001283010.1 1917045 D 419947 CDS YP_001283011.1 148661488 5214287 1917467..1918219 1 NC_009525.1 hypothetical protein 1918219 5214287 MRA_1701 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283011.1 1917467 D 419947 CDS YP_001283012.1 148661489 5214288 1918216..1919277 1 NC_009525.1 phosphatase 1919277 5214288 MRA_1702 Mycobacterium tuberculosis H37Ra phosphatase YP_001283012.1 1918216 D 419947 CDS YP_001283013.1 148661490 5215126 1919274..1919450 1 NC_009525.1 hypothetical protein 1919450 5215126 MRA_1702A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283013.1 1919274 D 419947 CDS YP_001283014.1 148661491 5215127 1919458..1920264 1 NC_009525.1 cytotoxin/hemolysin 1920264 tlyA 5215127 tlyA Mycobacterium tuberculosis H37Ra cytotoxin/hemolysin YP_001283014.1 1919458 D 419947 CDS YP_001283015.1 148661492 5215128 1920264..1921187 1 NC_009525.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1921187 ppnK 5215128 ppnK Mycobacterium tuberculosis H37Ra inorganic polyphosphate/ATP-NAD kinase YP_001283015.1 1920264 D 419947 CDS YP_001283016.1 148661493 5215129 1921201..1922964 1 NC_009525.1 DNA repair protein RecN 1922964 recN 5215129 recN Mycobacterium tuberculosis H37Ra DNA repair protein RecN YP_001283016.1 1921201 D 419947 CDS YP_001283017.1 148661494 5215130 1923060..1924241 1 NC_009525.1 hypothetical protein 1924241 5215130 MRA_1706 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283017.1 1923060 D 419947 CDS YP_001283018.1 148661495 5215131 1924263..1925207 1 NC_009525.1 hypothetical protein 1925207 5215131 MRA_1707 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283018.1 1924263 D 419947 CDS YP_001283019.1 148661496 5215132 1925347..1927107 1 NC_009525.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1927107 pyrG 5215132 pyrG Mycobacterium tuberculosis H37Ra CTP synthetase YP_001283019.1 1925347 D 419947 CDS YP_001283020.1 148661497 5215133 1927100..1927723 1 NC_009525.1 MutT/nudix family protein 1927723 5215133 MRA_1709 Mycobacterium tuberculosis H37Ra MutT/nudix family protein YP_001283020.1 1927100 D 419947 CDS YP_001283021.1 148661498 5215312 1927720..1928655 1 NC_009525.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1928655 xerD 5215312 xerD Mycobacterium tuberculosis H37Ra site-specific tyrosine recombinase XerD YP_001283021.1 1927720 D 419947 CDS YP_001283022.1 148661499 5215313 complement(1928729..1930093) 1 NC_009525.1 hypothetical protein 1930093 5215313 MRA_1711 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283022.1 1928729 R 419947 CDS YP_001283023.1 148661500 5215314 complement(1930649..1931239) 1 NC_009525.1 catechol-O-methyltransferase 1931239 5215314 MRA_1712 Mycobacterium tuberculosis H37Ra catechol-O-methyltransferase YP_001283023.1 1930649 R 419947 CDS YP_001283024.1 148661501 5215315 complement(1931304..1932974) 1 NC_009525.1 D-serine/alanine/glycine transporter protein CycA 1932974 cycA 5215315 cycA Mycobacterium tuberculosis H37Ra D-serine/alanine/glycine transporter protein CycA YP_001283024.1 1931304 R 419947 CDS YP_001283025.1 148661502 5215316 complement(1933015..1934172) 1 NC_009525.1 PPE family protein 1934172 5215316 MRA_1714 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283025.1 1933015 R 419947 CDS YP_001283026.1 148661503 5215317 complement(1934212..1935396) 1 NC_009525.1 PPE family protein 1935396 5215317 MRA_1715 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283026.1 1934212 R 419947 CDS YP_001283027.1 148661504 5215318 complement(1936000..1936167) 1 NC_009525.1 hypothetical protein 1936167 5215318 MRA_1716 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283027.1 1936000 R 419947 CDS YP_001283028.1 148661505 5215319 1936400..1937860 1 NC_009525.1 sulfate transporter 1937860 5215319 MRA_1717 Mycobacterium tuberculosis H37Ra sulfate transporter YP_001283028.1 1936400 D 419947 CDS YP_001283029.1 148661506 5215338 1937878..1938834 1 NC_009525.1 initiation inhibitor protein 1938834 5215338 MRA_1718 Mycobacterium tuberculosis H37Ra initiation inhibitor protein YP_001283029.1 1937878 D 419947 CDS YP_001283030.1 148661507 5215339 1938831..1939667 1 NC_009525.1 segregation and condensation protein 1939667 5215339 MRA_1719 Mycobacterium tuberculosis H37Ra segregation and condensation protein YP_001283030.1 1938831 D 419947 CDS YP_001283031.1 148661508 5215340 1939664..1940359 1 NC_009525.1 hypothetical protein 1940359 5215340 MRA_1720 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283031.1 1939664 D 419947 CDS YP_001283032.1 148661509 5215341 1940356..1941120 1 NC_009525.1 RNA pseudouridylate synthase 1941120 5215341 MRA_1721 Mycobacterium tuberculosis H37Ra RNA pseudouridylate synthase YP_001283032.1 1940356 D 419947 CDS YP_001283033.1 148661510 5215342 1941117..1941809 1 NC_009525.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1941809 cmk 5215342 cmk Mycobacterium tuberculosis H37Ra cytidylate kinase YP_001283033.1 1941117 D 419947 CDS YP_001283034.1 148661511 5215343 1941806..1943197 1 NC_009525.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1943197 engA 5215343 engA Mycobacterium tuberculosis H37Ra GTP-binding protein EngA YP_001283034.1 1941806 D 419947 CDS YP_001283035.1 148661512 5215344 1943371..1944183 1 NC_009525.1 oxidoreductase 1944183 5215344 MRA_1724 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001283035.1 1943371 D 419947 CDS YP_001283036.1 148661513 5215345 1944177..1945091 1 NC_009525.1 3-hydroxyacyl-CoA dehydrogenase 1945091 fadB3 5215345 fadB3 Mycobacterium tuberculosis H37Ra 3-hydroxyacyl-CoA dehydrogenase YP_001283036.1 1944177 D 419947 CDS YP_001283037.1 148661514 5215391 1945094..1945924 1 NC_009525.1 hypothetical protein 1945924 5215391 MRA_1726 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283037.1 1945094 D 419947 CDS YP_001283038.1 148661515 5215392 1945924..1946274 1 NC_009525.1 hypothetical protein 1946274 5215392 MRA_1727 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283038.1 1945924 D 419947 CDS YP_001283039.1 148661516 5215393 1946327..1947145 1 NC_009525.1 hypothetical protein 1947145 5215393 MRA_1728 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283039.1 1946327 D 419947 CDS YP_001283040.1 148661517 5215394 1947159..1947938 1 NC_009525.1 Crp family transcriptional regulator 1947938 5215394 MRA_1729 Mycobacterium tuberculosis H37Ra Crp family transcriptional regulator YP_001283040.1 1947159 D 419947 CDS YP_001283041.1 148661518 5215396 complement(1948548..1948937) 1 NC_009525.1 hypothetical protein 1948937 5215396 MRA_1730 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283041.1 1948548 R 419947 CDS YP_001283042.1 148661519 5215397 complement(1948934..1949161) 1 NC_009525.1 hypothetical protein 1949161 5215397 MRA_1731 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283042.1 1948934 R 419947 CDS YP_001283043.1 148661520 5215529 1949379..1950863 1 NC_009525.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase-like protein 1950863 5215529 MRA_1732 Mycobacterium tuberculosis H37Ra biotin carboxylase-like protein YP_001283043.1 1949379 D 419947 CDS YP_001283044.1 148661521 5215530 1950860..1952107 1 NC_009525.1 hydrolase 1952107 5215530 MRA_1733 Mycobacterium tuberculosis H37Ra hydrolase YP_001283044.1 1950860 D 419947 CDS YP_001283045.1 148661522 5215531 complement(1952150..1952569) 1 NC_009525.1 hypothetical protein 1952569 5215531 MRA_1734 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283045.1 1952150 R 419947 CDS YP_001283046.1 148661523 5215532 complement(1952559..1953269) 1 NC_009525.1 hypothetical protein 1953269 5215532 MRA_1735 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283046.1 1952559 R 419947 CDS YP_001283047.1 148661524 5215533 1953370..1954755 1 NC_009525.1 oxidoreductase 1954755 5215533 MRA_1736 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001283047.1 1953370 D 419947 CDS YP_001283048.1 148661525 5215534 1954788..1955357 1 NC_009525.1 hypothetical protein 1955357 5215534 MRA_1737 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283048.1 1954788 D 419947 CDS YP_001283049.1 148661526 5215535 complement(1955382..1956152) 1 NC_009525.1 hypothetical protein 1956152 5215535 MRA_1738 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283049.1 1955382 R 419947 CDS YP_001283050.1 148661527 5215536 complement(1956149..1957087) 1 NC_009525.1 hypothetical protein 1957087 5215536 MRA_1739 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283050.1 1956149 R 419947 CDS YP_001283051.1 148661528 5211889 complement(1957210..1958763) 1 NC_009525.1 penicillin-binding protein 1958763 5211889 MRA_1740 Mycobacterium tuberculosis H37Ra penicillin-binding protein YP_001283051.1 1957210 R 419947 CDS YP_001283052.1 148661529 5211890 1959195..1960751 1 NC_009525.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase 1960751 gabD2 5211890 gabD2 Mycobacterium tuberculosis H37Ra succinic semialdehyde dehydrogenase YP_001283052.1 1959195 D 419947 CDS YP_001283053.1 148661530 5211891 complement(1960761..1961309) 1 NC_009525.1 hypothetical protein 1961309 5211891 MRA_1742 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283053.1 1960761 R 419947 CDS YP_001283054.1 148661531 5211892 complement(1961373..1962005) 1 NC_009525.1 transmembrane protein 1962005 5211892 MRA_1743 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283054.1 1961373 R 419947 CDS YP_001283055.1 148661532 5211893 complement(1962292..1962534) 1 NC_009525.1 hypothetical protein 1962534 5211893 MRA_1744 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283055.1 1962292 R 419947 CDS YP_001283056.1 148661533 5211894 complement(1962809..1963306) 1 NC_009525.1 hypothetical protein 1963306 5211894 MRA_1745 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283056.1 1962809 R 419947 CDS YP_001283057.1 148661534 5211895 complement(1963405..1963647) 1 NC_009525.1 hypothetical protein 1963647 5211895 MRA_1746 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283057.1 1963405 R 419947 CDS YP_001283058.1 148661535 5211896 complement(1963746..1965704) 1 NC_009525.1 nitrate reductase NarX 1965704 narX 5211896 narX Mycobacterium tuberculosis H37Ra nitrate reductase NarX YP_001283058.1 1963746 R 419947 CDS YP_001283059.1 148661536 5212524 complement(1965701..1966888) 1 NC_009525.1 nitrate/nitrite transporter NarK2 1966888 narK2 5212524 narK2 Mycobacterium tuberculosis H37Ra nitrate/nitrite transporter NarK2 YP_001283059.1 1965701 R 419947 CDS YP_001283060.1 148661537 5212525 1967127..1967459 1 NC_009525.1 hypothetical protein 1967459 5212525 MRA_1749 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283060.1 1967127 D 419947 CDS YP_001283061.1 148661538 5212526 complement(1967473..1969155) 1 NC_009525.1 sulfate transporter 1969155 5212526 MRA_1750 Mycobacterium tuberculosis H37Ra sulfate transporter YP_001283061.1 1967473 R 419947 CDS YP_001283062.1 148661539 5212527 1969223..1969435 1 NC_009525.1 hypothetical protein 1969435 5212527 MRA_1751 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283062.1 1969223 D 419947 CDS YP_001283063.1 148661540 5212528 1969435..1969683 1 NC_009525.1 hypothetical protein 1969683 5212528 MRA_1752 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283063.1 1969435 D 419947 CDS YP_001283064.1 148661541 5212529 1969691..1970428 1 NC_009525.1 hypothetical protein 1970428 5212529 MRA_1753 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283064.1 1969691 D 419947 CDS YP_001283065.1 148661542 5212530 1970522..1972222 1 NC_009525.1 serine/threonine protein kinase 1972222 pknE 5212530 pknE Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001283065.1 1970522 D 419947 CDS YP_001283066.1 148661543 5212531 complement(1972507..1972908) 1 NC_009525.1 hypothetical protein 1972908 5212531 MRA_1755 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283066.1 1972507 R 419947 CDS YP_001283067.1 148661544 5211798 complement(1972898..1973509) 1 NC_009525.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 1973509 idi 5211798 idi Mycobacterium tuberculosis H37Ra isopentenyl-diphosphate delta-isomerase YP_001283067.1 1972898 R 419947 CDS YP_001283068.1 148661545 5211799 1973656..1975086 1 NC_009525.1 serine/threonine protein kinase 1975086 pknF 5211799 pknF Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001283068.1 1973656 D 419947 CDS YP_001283069.1 148661546 5211800 1975148..1977745 1 NC_009525.1 ABC transporter ATP-binding protein 1977745 5211800 MRA_1758 Mycobacterium tuberculosis H37Ra ABC transporter ATP-binding protein YP_001283069.1 1975148 D 419947 CDS YP_001283070.1 148661547 5211801 1978118..1978849 1 NC_009525.1 hypothetical protein 1978849 5211801 MRA_1759 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283070.1 1978118 D 419947 CDS YP_001283071.1 148661548 5211802 complement(1978846..1979403) 1 NC_009525.1 integral membrane protein 1979403 5211802 MRA_1760 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283071.1 1978846 R 419947 CDS YP_001283072.1 148661549 5211803 complement(1979487..1981085) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1981085 fadD1 5211803 fadD1 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001283072.1 1979487 R 419947 CDS YP_001283073.1 148661550 5211804 1981139..1982521 1 NC_009525.1 hypothetical protein 1982521 5211804 MRA_1762 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283073.1 1981139 D 419947 CDS YP_001283074.1 148661551 5211805 1982648..1983097 1 NC_009525.1 hypothetical protein 1983097 5211805 MRA_1763 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283074.1 1982648 D 419947 CDS YP_001283075.1 148661552 5212115 complement(1983132..1986293) 1 NC_009525.1 PPE family protein 1986293 5212115 MRA_1764 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283075.1 1983132 R 419947 CDS YP_001283076.1 148661553 5212116 complement(1986497..1988188) 1 NC_009525.1 hypothetical protein 1988188 5212116 MRA_1765 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283076.1 1986497 R 419947 CDS YP_001283077.1 148661554 5212117 complement(1988372..1989403) 1 NC_009525.1 phospholipase C 4 PlcD 1989403 plcD 5212117 plcD Mycobacterium tuberculosis H37Ra phospholipase C 4 PlcD YP_001283077.1 1988372 R 419947 CDS YP_001283078.1 148661555 5212118 complement(1989483..1990367) 1 NC_009525.1 IS6110 transposase 1990367 5212118 MRA_1767 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283078.1 1989483 R 419947 CDS YP_001283079.1 148661556 5212119 complement(1990418..1990744) 1 NC_009525.1 IS6110 hypothetical protein 1990744 5212119 MRA_1768 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283079.1 1990418 R 419947 CDS YP_001283080.1 148661557 5212120 complement(1990519..1991274) 1 NC_009525.1 hypothetical protein 1991274 5212120 MRA_1768A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283080.1 1990519 R 419947 CDS YP_001283081.1 148661558 5212121 complement(1991403..1992548) 1 NC_009525.1 hypothetical protein 1992548 5212121 MRA_1768B Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283081.1 1991403 R 419947 CDS YP_001283082.1 148661559 5212122 1992738..1993877 1 NC_009525.1 sulfite oxidase 1993877 5212122 MRA_1768C Mycobacterium tuberculosis H37Ra sulfite oxidase YP_001283082.1 1992738 D 419947 CDS YP_001283083.1 148661560 5215580 1994078..1996915 1 NC_009525.1 transmembrane transport protein MmpL14 1996915 mmpL14 5215580 mmpL14 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL14 YP_001283083.1 1994078 D 419947 CDS YP_001283084.1 148661561 5215581 complement(1997429..1998313) 1 NC_009525.1 IS6110 transposase 1998313 5215581 MRA_1769 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283084.1 1997429 R 419947 CDS YP_001283085.1 148661562 5215582 complement(1998364..1998690) 1 NC_009525.1 IS6110 hypothetical protein 1998690 5215582 MRA_1770 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283085.1 1998364 R 419947 CDS YP_001283086.1 148661563 5215583 1998726..1999250 1 NC_009525.1 cutinase Cut1 1999250 cut1 5215583 cut1 Mycobacterium tuberculosis H37Ra cutinase Cut1 YP_001283086.1 1998726 D 419947 CDS YP_001283087.1 148661564 5215584 complement(2001912..2002382) 1 NC_009525.1 PE-PGRS family protein 2002382 5215584 MRA_1772 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283087.1 2001912 R 419947 CDS YP_001283088.1 148661565 5215585 2002424..2002657 1 NC_009525.1 hypothetical protein 2002657 5215585 MRA_1773 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283088.1 2002424 D 419947 CDS YP_001283089.1 148661566 5215586 2002838..2004346 1 NC_009525.1 hypothetical protein 2004346 5215586 MRA_1774 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283089.1 2002838 D 419947 CDS YP_001283090.1 148661567 5212787 complement(2004356..2004739) 1 NC_009525.1 hypothetical protein 2004739 5212787 MRA_1775 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283090.1 2004356 R 419947 CDS YP_001283091.1 148661568 5212788 complement(2004739..2005527) 1 NC_009525.1 hypothetical protein 2005527 5212788 MRA_1776 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283091.1 2004739 R 419947 CDS YP_001283092.1 148661569 5212789 2005837..2006163 1 NC_009525.1 IS6110 hypothetical protein 2006163 5212789 MRA_1777 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283092.1 2005837 D 419947 CDS YP_001283093.1 148661570 5212790 2006214..2007098 1 NC_009525.1 IS6110 transposase 2007098 5212790 MRA_1778 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283093.1 2006214 D 419947 CDS YP_001283094.1 148661571 5212791 2006965..2007345 1 NC_009525.1 truncated IS6110 transposase 2007345 5212791 MRA_1779 Mycobacterium tuberculosis H37Ra truncated IS6110 transposase YP_001283094.1 2006965 D 419947 CDS YP_001283095.1 148661572 5212792 complement(2007350..2008447) 1 NC_009525.1 hypothetical protein 2008447 5212792 MRA_1780 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283095.1 2007350 R 419947 CDS YP_001283096.1 148661573 5212793 complement(2009074..2009289) 1 NC_009525.1 transposase 2009289 5212793 MRA_1781 Mycobacterium tuberculosis H37Ra transposase YP_001283096.1 2009074 R 419947 CDS YP_001283097.1 148661574 5212794 2009669..2009938 1 NC_009525.1 hypothetical protein 2009938 5212794 MRA_1782 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283097.1 2009669 D 419947 CDS YP_001283098.1 148661575 5214023 2010006..2010365 1 NC_009525.1 hypothetical protein 2010365 5214023 MRA_1783 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283098.1 2010006 D 419947 CDS YP_001283099.1 148661576 5214024 2010546..2012402 1 NC_009525.1 PE-PGRS family protein 2012402 5214024 MRA_1784 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283099.1 2010546 D 419947 CDS YP_001283100.1 148661577 5214025 2012558..2013802 1 NC_009525.1 hypothetical protein 2013802 5214025 MRA_1785 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283100.1 2012558 D 419947 CDS YP_001283101.1 148661578 5214026 2013810..2015096 1 NC_009525.1 hypothetical protein 2015096 5214026 MRA_1786 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283101.1 2013810 D 419947 CDS YP_001283102.1 148661579 5214027 2015093..2016379 1 NC_009525.1 oxidoreductase 2016379 5214027 MRA_1787 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001283102.1 2015093 D 419947 CDS YP_001283103.1 148661580 5214028 2016568..2016879 1 NC_009525.1 hypothetical protein 2016879 5214028 MRA_1788 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283103.1 2016568 D 419947 CDS YP_001283104.1 148661581 5214029 complement(2016952..2017698) 1 NC_009525.1 IclR family transcriptional regulator 2017698 5214029 MRA_1789 Mycobacterium tuberculosis H37Ra IclR family transcriptional regulator YP_001283104.1 2016952 R 419947 CDS YP_001283105.1 148661582 5214030 2017764..2019104 1 NC_009525.1 oxidoreductase 2019104 5214030 MRA_1790 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001283105.1 2017764 D 419947 CDS YP_001283106.1 148661583 5214506 2019104..2019922 1 NC_009525.1 hypothetical protein 2019922 5214506 MRA_1791 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283106.1 2019104 D 419947 CDS YP_001283107.1 148661584 5214507 complement(2019927..2020487) 1 NC_009525.1 transcriptional regulatory protein 2020487 5214507 MRA_1792 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283107.1 2019927 R 419947 CDS YP_001283108.1 148661585 5214508 2020588..2021892 1 NC_009525.1 cytochrome p450 144 CYP144 2021892 cyp144 5214508 cyp144 Mycobacterium tuberculosis H37Ra cytochrome p450 144 CYP144 YP_001283108.1 2020588 D 419947 CDS YP_001283109.1 148661586 5214509 complement(2022013..2022462) 1 NC_009525.1 hypothetical protein 2022462 5214509 MRA_1794 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283109.1 2022013 R 419947 CDS YP_001283110.1 148661587 5214510 complement(2022618..2024411) 1 NC_009525.1 hypothetical protein 2024411 5214510 MRA_1795 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283110.1 2022618 R 419947 CDS YP_001283111.1 148661588 5214511 2024631..2025194 1 NC_009525.1 hypothetical protein 2025194 5214511 MRA_1795A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283111.1 2024631 D 419947 CDS YP_001283112.1 148661589 5214512 complement(2025234..2027408) 1 NC_009525.1 4-alpha-glucanotransferase 2027408 malQ 5214512 malQ Mycobacterium tuberculosis H37Ra 4-alpha-glucanotransferase YP_001283112.1 2025234 R 419947 CDS YP_001283113.1 148661590 5214513 2027672..2029192 1 NC_009525.1 hypothetical protein 2029192 5214513 MRA_1797 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283113.1 2027672 D 419947 CDS YP_001283114.1 148661591 5215504 2029189..2033364 1 NC_009525.1 DNA translocase FtsK 2033364 5215504 MRA_1798 Mycobacterium tuberculosis H37Ra DNA translocase FtsK YP_001283114.1 2029189 D 419947 CDS YP_001283115.1 148661592 5215505 complement(2033379..2034560) 1 NC_009525.1 cytochrome p450 143 CYP143 2034560 cyp143 5215505 cyp143 Mycobacterium tuberculosis H37Ra cytochrome p450 143 CYP143 YP_001283115.1 2033379 R 419947 CDS YP_001283116.1 148661593 5215506 2034760..2034963 1 NC_009525.1 ferredoxin 2034963 5215506 MRA_1800 Mycobacterium tuberculosis H37Ra ferredoxin YP_001283116.1 2034760 D 419947 CDS YP_001283117.1 148661594 5215507 2035113..2036330 1 NC_009525.1 PPE family protein 2036330 5215507 MRA_1801 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283117.1 2035113 D 419947 CDS YP_001283118.1 148661595 5215508 2036409..2036708 1 NC_009525.1 PE family protein 2036708 5215508 MRA_1802 Mycobacterium tuberculosis H37Ra PE family protein YP_001283118.1 2036409 D 419947 CDS YP_001283119.1 148661596 5215509 2036722..2037903 1 NC_009525.1 PPE family protein 2037903 5215509 MRA_1803 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283119.1 2036722 D 419947 CDS YP_001283120.1 148661597 5215510 2038357..2039409 1 NC_009525.1 PPE family protein 2039409 5215510 MRA_1804 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283120.1 2038357 D 419947 CDS YP_001283121.1 148661598 5215511 2039836..2040135 1 NC_009525.1 PE family protein 2040135 5215511 MRA_1805 Mycobacterium tuberculosis H37Ra PE family protein YP_001283121.1 2039836 D 419947 CDS YP_001283122.1 148661599 5212171 2040626..2040910 1 NC_009525.1 esat-6 like protein EsxN 2040910 esxN 5212171 esxN Mycobacterium tuberculosis H37Ra esat-6 like protein EsxN YP_001283122.1 2040626 D 419947 CDS YP_001283123.1 148661600 5212172 2040998..2041900 1 NC_009525.1 hypothetical protein 2041900 5212172 MRA_1807 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283123.1 2040998 D 419947 CDS YP_001283124.1 148661601 5212173 2042172..2043683 1 NC_009525.1 hypothetical protein 2043683 5212173 MRA_1808 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283124.1 2042172 D 419947 CDS YP_001283125.1 148661602 5212174 2043661..2045418 1 NC_009525.1 proline rich membrane-anchored mycosin MycP5 2045418 mycP5 5212174 mycP5 Mycobacterium tuberculosis H37Ra proline rich membrane-anchored mycosin MycP5 YP_001283125.1 2043661 D 419947 CDS YP_001283126.1 148661603 5212175 2045415..2046635 1 NC_009525.1 hypothetical protein 2046635 5212175 MRA_1810 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283126.1 2045415 D 419947 CDS YP_001283127.1 148661604 5212176 2046632..2048464 1 NC_009525.1 hypothetical protein 2048464 5212176 MRA_1811 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283127.1 2046632 D 419947 CDS YP_001283128.1 148661605 5212177 2049091..2049282 1 NC_009525.1 lipoprotein LppT 2049282 lppT 5212177 lppT Mycobacterium tuberculosis H37Ra lipoprotein LppT YP_001283128.1 2049091 D 419947 CDS YP_001283129.1 148661606 5212178 2049385..2051352 1 NC_009525.1 PPE family protein 2051352 5212178 MRA_1813 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283129.1 2049385 D 419947 CDS YP_001283130.1 148661607 5214164 2051933..2053204 1 NC_009525.1 PPE family protein 2053204 5214164 MRA_1814 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283130.1 2051933 D 419947 CDS YP_001283131.1 148661608 5214165 2053316..2054707 1 NC_009525.1 PPE family protein 2054707 5214165 MRA_1815 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283131.1 2053316 D 419947 CDS YP_001283132.1 148661609 5214166 complement(2054855..2056807) 1 NC_009525.1 PE-PGRS family protein 2056807 5214166 MRA_1816 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283132.1 2054855 R 419947 CDS YP_001283133.1 148661610 5214167 complement(2056955..2057281) 1 NC_009525.1 hypothetical protein 2057281 5214167 MRA_1817 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283133.1 2056955 R 419947 CDS YP_001283134.1 148661611 5214168 complement(2057619..2057966) 1 NC_009525.1 hypothetical protein 2057966 5214168 MRA_1817A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283134.1 2057619 R 419947 CDS YP_001283135.1 148661612 5214169 2058004..2058303 1 NC_009525.1 PE family protein 2058303 5214169 MRA_1818 Mycobacterium tuberculosis H37Ra PE family protein YP_001283135.1 2058004 D 419947 CDS YP_001283136.1 148661613 5214170 2058318..2059529 1 NC_009525.1 PPE family protein 2059529 5214170 MRA_1819 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283136.1 2058318 D 419947 CDS YP_001283137.1 148661614 5214171 2059853..2061082 1 NC_009525.1 PPE family protein 2061082 5214171 MRA_1820 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283137.1 2059853 D 419947 CDS YP_001283138.1 148661615 5211634 2061214..2062620 1 NC_009525.1 PPE family protein 2062620 5211634 MRA_1821 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283138.1 2061214 D 419947 CDS YP_001283139.1 148661616 5211667 2062865..2063221 1 NC_009525.1 hypothetical protein 2063221 5211667 MRA_1822 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283139.1 2062865 D 419947 CDS YP_001283140.1 148661617 5211668 2063375..2064079 1 NC_009525.1 Mg2+ transport P-type ATPase C 2064079 mgtC 5211668 mgtC Mycobacterium tuberculosis H37Ra Mg2+ transport P-type ATPase C YP_001283140.1 2063375 D 419947 CDS YP_001283141.1 148661618 5211669 complement(2064089..2065291) 1 NC_009525.1 dehydrogenase 2065291 5211669 MRA_1824 Mycobacterium tuberculosis H37Ra dehydrogenase YP_001283141.1 2064089 R 419947 CDS YP_001283142.1 148661619 5211670 complement(2065613..2066044) 1 NC_009525.1 hypothetical protein 2066044 5211670 MRA_1825 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283142.1 2065613 R 419947 CDS YP_001283143.1 148661620 5211671 2066453..2067355 1 NC_009525.1 sterol desaturase-related protein 2067355 erg3 5211671 erg3 Mycobacterium tuberculosis H37Ra sterol desaturase-related protein YP_001283143.1 2066453 D 419947 CDS YP_001283144.1 148661621 5211672 2067460..2068125 1 NC_009525.1 hypothetical protein 2068125 5211672 MRA_1827 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283144.1 2067460 D 419947 CDS YP_001283145.1 148661622 5211673 2068188..2068892 1 NC_009525.1 transcriptional regulatory protein 2068892 5211673 MRA_1828 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283145.1 2068188 D 419947 CDS YP_001283146.1 148661623 5211674 2069527..2070990 1 NC_009525.1 hypothetical protein 2070990 5211674 MRA_1829 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283146.1 2069527 D 419947 CDS YP_001283147.1 148661624 5213457 complement(2071110..2072606) 1 NC_009525.1 PE-PGRS family protein 2072606 5213457 MRA_1830 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283147.1 2071110 R 419947 CDS YP_001283148.1 148661625 5213458 complement(2072741..2074660) 1 NC_009525.1 ABC transporter ATP-binding protein 2074660 5213458 MRA_1831 Mycobacterium tuberculosis H37Ra ABC transporter ATP-binding protein YP_001283148.1 2072741 R 419947 CDS YP_001283149.1 148661626 5213459 2074731..2076374 1 NC_009525.1 hypothetical protein 2076374 ilvG 5213459 ilvG Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283149.1 2074731 D 419947 CDS YP_001283150.1 148661627 5213460 2076389..2078815 1 NC_009525.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 2078815 secA2 5213460 secA2 Mycobacterium tuberculosis H37Ra preprotein translocase subunit SecA YP_001283150.1 2076389 D 419947 CDS YP_001283151.1 148661628 5213461 2079012..2079641 1 NC_009525.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2079641 pgsA2 5213461 pgsA2 Mycobacterium tuberculosis H37Ra CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001283151.1 2079012 D 419947 CDS YP_001283152.1 148661629 5213462 2079634..2080557 1 NC_009525.1 hypothetical protein 2080557 5213462 MRA_1835 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283152.1 2079634 D 419947 CDS YP_001283153.1 148661630 5213463 2080586..2080951 1 NC_009525.1 small basic protein 2080951 5213463 MRA_1836 Mycobacterium tuberculosis H37Ra small basic protein YP_001283153.1 2080586 D 419947 CDS YP_001283154.1 148661631 5213464 2080968..2081846 1 NC_009525.1 hypothetical protein 2081846 5213464 MRA_1837 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283154.1 2080968 D 419947 CDS YP_001283155.1 148661632 5211844 2081884..2082288 1 NC_009525.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 2082288 gcvH 5211844 gcvH Mycobacterium tuberculosis H37Ra glycine cleavage system protein H YP_001283155.1 2081884 D 419947 CDS YP_001283156.1 148661633 5211845 2082528..2083016 1 NC_009525.1 hypothetical protein 2083016 cfp17 5211845 cfp17 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283156.1 2082528 D 419947 CDS YP_001283157.1 148661634 5211846 2083013..2083756 1 NC_009525.1 hypothetical protein 2083756 5211846 MRA_1840 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283157.1 2083013 D 419947 CDS YP_001283158.1 148661635 5211847 2083875..2084369 1 NC_009525.1 hypothetical protein 2084369 5211847 MRA_1841 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283158.1 2083875 D 419947 CDS YP_001283159.1 148661636 5211848 2084773..2085450 1 NC_009525.1 hypothetical protein 2085450 5211848 MRA_1842 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283159.1 2084773 D 419947 CDS YP_001283160.1 148661637 5211849 2085503..2085760 1 NC_009525.1 hypothetical protein 2085760 5211849 MRA_1842A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283160.1 2085503 D 419947 CDS YP_001283161.1 148661638 5211850 2085809..2088634 1 NC_009525.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 2088634 gcvB 5211850 gcvB Mycobacterium tuberculosis H37Ra glycine dehydrogenase YP_001283161.1 2085809 D 419947 CDS YP_001283162.1 148661639 5211851 complement(2088861..2089721) 1 NC_009525.1 haloalkane dehalogenase 2089721 5211851 MRA_1844 Mycobacterium tuberculosis H37Ra haloalkane dehalogenase YP_001283162.1 2088861 R 419947 CDS YP_001283163.1 148661640 5213826 2089762..2090628 1 NC_009525.1 hydrolase 2090628 5213826 MRA_1845 Mycobacterium tuberculosis H37Ra hydrolase YP_001283163.1 2089762 D 419947 CDS YP_001283164.1 148661641 5213827 complement(2090633..2092519) 1 NC_009525.1 hypothetical protein 2092519 5213827 MRA_1846 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283164.1 2090633 R 419947 CDS YP_001283165.1 148661642 5213828 complement(2092535..2094568) 1 NC_009525.1 hypothetical protein 2094568 5213828 MRA_1847 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283165.1 2092535 R 419947 CDS YP_001283166.1 148661643 5213829 complement(2094688..2096913) 1 NC_009525.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 2096913 glcB 5213829 glcB Mycobacterium tuberculosis H37Ra malate synthase G YP_001283166.1 2094688 R 419947 CDS YP_001283167.1 148661644 5213830 complement(2097189..2097584) 1 NC_009525.1 hypothetical protein 2097584 5213830 MRA_1849 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283167.1 2097189 R 419947 CDS YP_001283168.1 148661645 5213831 complement(2097581..2097844) 1 NC_009525.1 hypothetical protein 2097844 5213831 MRA_1850 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283168.1 2097581 R 419947 CDS YP_001283169.1 148661646 5213832 complement(2097903..2099450) 1 NC_009525.1 PE-PGRS family protein 2099450 5213832 MRA_1851 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283169.1 2097903 R 419947 CDS YP_001283170.1 148661647 5213833 complement(2099613..2100650) 1 NC_009525.1 hypothetical protein 2100650 5213833 MRA_1852 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283170.1 2099613 R 419947 CDS YP_001283171.1 148661648 5214416 complement(2100650..2102017) 1 NC_009525.1 hypothetical protein 2102017 5214416 MRA_1853 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283171.1 2100650 R 419947 CDS YP_001283172.1 148661649 5214417 complement(2102191..2103630) 1 NC_009525.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 2103630 guaB1 5214417 guaB1 Mycobacterium tuberculosis H37Ra inosine 5-monophosphate dehydrogenase YP_001283172.1 2102191 R 419947 CDS YP_001283173.1 148661650 5214418 complement(2103663..2105120) 1 NC_009525.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2105120 gnd1 5214418 gnd1 Mycobacterium tuberculosis H37Ra 6-phosphogluconate dehydrogenase YP_001283173.1 2103663 R 419947 CDS YP_001283174.1 148661651 5214419 complement(2105150..2106100) 1 NC_009525.1 hypothetical protein 2106100 5214419 MRA_1856 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283174.1 2105150 R 419947 CDS YP_001283175.1 148661652 5214420 complement(2106115..2106531) 1 NC_009525.1 transcriptional regulatory protein 2106531 5214420 MRA_1857 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283175.1 2106115 R 419947 CDS YP_001283176.1 148661653 5214421 2106809..2107231 1 NC_009525.1 hypothetical protein 2107231 5214421 MRA_1858 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283176.1 2106809 D 419947 CDS YP_001283177.1 148661654 5214422 2107280..2107582 1 NC_009525.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 2107582 ureA 5214422 ureA Mycobacterium tuberculosis H37Ra urease subunit gamma YP_001283177.1 2107280 D 419947 CDS YP_001283178.1 148661655 5214423 2107579..2107893 1 NC_009525.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); urease subunit beta 2107893 ureB 5214423 ureB Mycobacterium tuberculosis H37Ra urease subunit beta YP_001283178.1 2107579 D 419947 CDS YP_001283179.1 148661656 5215091 2107893..2109626 1 NC_009525.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 2109626 ureC 5215091 ureC Mycobacterium tuberculosis H37Ra urease subunit alpha YP_001283179.1 2107893 D 419947 CDS YP_001283180.1 148661657 5215092 2109626..2110261 1 NC_009525.1 urease accessory protein UreF 2110261 ureF 5215092 ureF Mycobacterium tuberculosis H37Ra urease accessory protein UreF YP_001283180.1 2109626 D 419947 CDS YP_001283181.1 148661658 5215093 2110272..2110946 1 NC_009525.1 urease accessory protein UreG 2110946 ureG 5215093 ureG Mycobacterium tuberculosis H37Ra urease accessory protein UreG YP_001283181.1 2110272 D 419947 CDS YP_001283182.1 148661659 5215094 2110954..2111580 1 NC_009525.1 urease accessory protein UreD 2111580 ureD 5215094 ureD Mycobacterium tuberculosis H37Ra urease accessory protein UreD YP_001283182.1 2110954 D 419947 CDS YP_001283183.1 148661660 5215095 complement(2111583..2112974) 1 NC_009525.1 NADH dehydrogenase Ndh 2112974 ndh 5215095 ndh Mycobacterium tuberculosis H37Ra NADH dehydrogenase Ndh YP_001283183.1 2111583 R 419947 CDS YP_001283184.1 148661661 5215096 complement(2113116..2114039) 1 NC_009525.1 oxidoreductase 2114039 5215096 MRA_1866 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001283184.1 2113116 R 419947 CDS YP_001283185.1 148661662 5215097 complement(2114078..2114755) 1 NC_009525.1 short chain dehydrogenase 2114755 5215097 MRA_1867 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001283185.1 2114078 R 419947 CDS YP_001283186.1 148661663 5215098 2114917..2115702 1 NC_009525.1 molybdate ABC transporter substrate-binding protein 2115702 modA 5215098 modA Mycobacterium tuberculosis H37Ra molybdate ABC transporter substrate-binding protein YP_001283186.1 2114917 D 419947 CDS YP_001283187.1 148661664 5212538 2115705..2116499 1 NC_009525.1 molybdate ABC transporter permease 2116499 modB 5212538 modB Mycobacterium tuberculosis H37Ra molybdate ABC transporter permease YP_001283187.1 2115705 D 419947 CDS YP_001283188.1 148661665 5212539 2116506..2117615 1 NC_009525.1 molybdate ABC transporter ATP-binding protein 2117615 modC 5212539 modC Mycobacterium tuberculosis H37Ra molybdate ABC transporter ATP-binding protein YP_001283188.1 2116506 D 419947 CDS YP_001283189.1 148661666 5212540 2117668..2118645 1 NC_009525.1 fibronectin attachment protein; hypothetical protein 2118645 apa 5212540 apa Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283189.1 2117668 D 419947 CDS YP_001283190.1 148661667 5212541 2119097..2119402 1 NC_009525.1 transmembrane protein 2119402 5212541 MRA_1872 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283190.1 2119097 D 419947 CDS YP_001283191.1 148661668 5212542 2119476..2120516 1 NC_009525.1 alcohol dehydrogenase 2120516 adhA 5212542 adhA Mycobacterium tuberculosis H37Ra alcohol dehydrogenase YP_001283191.1 2119476 D 419947 CDS YP_001283192.1 148661669 5212543 complement(2120523..2121293) 1 NC_009525.1 integral membrane protein 2121293 5212543 MRA_1874 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283192.1 2120523 R 419947 CDS YP_001283193.1 148661670 5212544 complement(2121286..2122041) 1 NC_009525.1 hypothetical protein 2122041 5212544 MRA_1875 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283193.1 2121286 R 419947 CDS YP_001283194.1 148661671 5212545 complement(2122038..2122898) 1 NC_009525.1 short chain dehydrogenase 2122898 5212545 MRA_1876 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001283194.1 2122038 R 419947 CDS YP_001283195.1 148661672 5214521 2122994..2125408 1 NC_009525.1 hypothetical protein 2125408 5214521 MRA_1877 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283195.1 2122994 D 419947 CDS YP_001283196.1 148661673 5214522 2125696..2127180 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 2127180 5214522 MRA_1878 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001283196.1 2125696 D 419947 CDS YP_001283197.1 148661674 5214523 2127279..2129378 1 NC_009525.1 hypothetical protein 2129378 5214523 MRA_1879 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283197.1 2127279 D 419947 CDS YP_001283198.1 148661675 5214524 complement(2129392..2130627) 1 NC_009525.1 ferredoxin reductase 2130627 5214524 MRA_1880 Mycobacterium tuberculosis H37Ra ferredoxin reductase YP_001283198.1 2129392 R 419947 CDS YP_001283199.1 148661676 5214525 complement(2130727..2131362) 1 NC_009525.1 hypothetical protein 2131362 5214525 MRA_1881 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283199.1 2130727 R 419947 CDS YP_001283200.1 148661677 5214526 complement(2131427..2131816) 1 NC_009525.1 hypothetical protein 2131816 5214526 MRA_1882 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283200.1 2131427 R 419947 CDS YP_001283201.1 148661678 5214527 complement(2131839..2133083) 1 NC_009525.1 L-lactate dehydrogenase 2133083 lldD2 5214527 lldD2 Mycobacterium tuberculosis H37Ra L-lactate dehydrogenase YP_001283201.1 2131839 R 419947 CDS YP_001283202.1 148661679 5214528 2133106..2133543 1 NC_009525.1 hypothetical protein 2133543 5214528 MRA_1884 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283202.1 2133106 D 419947 CDS YP_001283203.1 148661680 5212179 2133616..2134302 1 NC_009525.1 hypothetical protein 2134302 5212179 MRA_1885 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283203.1 2133616 D 419947 CDS YP_001283204.1 148661681 5212180 2134313..2134756 1 NC_009525.1 hypothetical protein 2134756 5212180 MRA_1886 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283204.1 2134313 D 419947 CDS YP_001283205.1 148661682 5212181 2135272..2135751 1 NC_009525.1 bacterioferritin 2135751 bfrA 5212181 bfrA Mycobacterium tuberculosis H37Ra bacterioferritin YP_001283205.1 2135272 D 419947 CDS YP_001283206.1 148661683 5212182 2135836..2137899 1 NC_009525.1 integral membrane protein 2137899 5212182 MRA_1888 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283206.1 2135836 D 419947 CDS YP_001283207.1 148661684 5212183 2137954..2139306 1 NC_009525.1 glutamine synthetase 2139306 glnA3 5212183 glnA3 Mycobacterium tuberculosis H37Ra glutamine synthetase YP_001283207.1 2137954 D 419947 CDS YP_001283208.1 148661685 5212184 2139309..2140445 1 NC_009525.1 hypothetical protein 2140445 5212184 MRA_1890 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283208.1 2139309 D 419947 CDS YP_001283209.1 148661686 5212185 complement(2140473..2141789) 1 NC_009525.1 cytochrome p450 140 CYP140 2141789 cyp140 5212185 cyp140 Mycobacterium tuberculosis H37Ra cytochrome p450 140 CYP140 YP_001283209.1 2140473 R 419947 CDS YP_001283210.1 148661687 5212186 complement(2141839..2142261) 1 NC_009525.1 lipoprotein LppE 2142261 lppE 5212186 lppE Mycobacterium tuberculosis H37Ra lipoprotein LppE YP_001283210.1 2141839 R 419947 CDS YP_001283211.1 148661688 5213277 complement(2142302..2143135) 1 NC_009525.1 short chain dehydrogenase 2143135 5213277 MRA_1893 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001283211.1 2142302 R 419947 CDS YP_001283212.1 148661689 5213278 complement(2143163..2143624) 1 NC_009525.1 hypothetical protein 2143624 5213278 MRA_1894 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283212.1 2143163 R 419947 CDS YP_001283213.1 148661690 5213279 complement(2143663..2144193) 1 NC_009525.1 resuscitation-promoting factor RpfC 2144193 rpfC 5213279 rpfC Mycobacterium tuberculosis H37Ra resuscitation-promoting factor RpfC YP_001283213.1 2143663 R 419947 CDS YP_001283214.1 148661691 5213280 complement(2144205..2144804) 1 NC_009525.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 2144804 5213280 MRA_1896 Mycobacterium tuberculosis H37Ra chorismate mutase YP_001283214.1 2144205 R 419947 CDS YP_001283215.1 148661692 5213281 complement(2144822..2145799) 1 NC_009525.1 secreted antigen 85-B FbpB 2145799 fbpB 5213281 fbpB Mycobacterium tuberculosis H37Ra secreted antigen 85-B FbpB YP_001283215.1 2144822 R 419947 CDS YP_001283216.1 148661693 5213282 2146190..2147332 1 NC_009525.1 hypothetical protein 2147332 5213282 MRA_1898 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283216.1 2146190 D 419947 CDS YP_001283217.1 148661694 5213283 complement(2147451..2148011) 1 NC_009525.1 transmembrane protein 2148011 5213283 MRA_1899 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283217.1 2147451 R 419947 CDS YP_001283218.1 148661695 5213284 complement(2148376..2148549) 1 NC_009525.1 hypothetical protein 2148549 5213284 MRA_1899A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283218.1 2148376 R 419947 CDS YP_001283219.1 148661696 5212146 complement(2148593..2148949) 1 NC_009525.1 hypothetical protein 2148949 5212146 MRA_1900 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283219.1 2148593 R 419947 CDS YP_001283220.1 148661697 5212147 complement(2149008..2149619) 1 NC_009525.1 hypothetical protein 2149619 5212147 MRA_1901 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283220.1 2149008 R 419947 CDS YP_001283221.1 148661698 5212148 2149673..2150080 1 NC_009525.1 hypothetical protein 2150080 5212148 MRA_1902 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283221.1 2149673 D 419947 CDS YP_001283222.1 148661699 5212149 2150097..2150408 1 NC_009525.1 hypothetical protein 2150408 5212149 MRA_1903 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283222.1 2150097 D 419947 CDS YP_001283223.1 148661700 5212150 2150418..2150636 1 NC_009525.1 hypothetical protein 2150636 5212150 MRA_1904 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283223.1 2150418 D 419947 CDS YP_001283224.1 148661701 5212151 complement(2150671..2151801) 1 NC_009525.1 hypothetical protein 2151801 5212151 MRA_1905 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283224.1 2150671 R 419947 CDS YP_001283225.1 148661702 5212152 2151874..2152305 1 NC_009525.1 hypothetical protein 2152305 5212152 MRA_1906 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283225.1 2151874 D 419947 CDS YP_001283226.1 148661703 5212153 2152453..2153607 1 NC_009525.1 dehydrogenase 2153607 5212153 MRA_1907 Mycobacterium tuberculosis H37Ra dehydrogenase YP_001283226.1 2152453 D 419947 CDS YP_001283227.1 148661704 5213007 complement(2153467..2154378) 1 NC_009525.1 hypothetical protein 2154378 5213007 MRA_1908 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283227.1 2153467 R 419947 CDS YP_001283228.1 148661705 5213008 complement(2154383..2154814) 1 NC_009525.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2154814 5213008 MRA_1909 Mycobacterium tuberculosis H37Ra D-tyrosyl-tRNA(Tyr) deacylase YP_001283228.1 2154383 R 419947 CDS YP_001283229.1 148661706 5213009 2154872..2155180 1 NC_009525.1 hypothetical protein 2155180 5213009 MRA_1909A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283229.1 2154872 D 419947 CDS YP_001283230.1 148661707 5213010 complement(2155146..2156177) 1 NC_009525.1 lipoprotein LppD 2156177 lppD 5213010 lppD Mycobacterium tuberculosis H37Ra lipoprotein LppD YP_001283230.1 2155146 R 419947 CDS YP_001283231.1 148661708 5213011 complement(2156177..2157565) 1 NC_009525.1 lignin peroxidase LipJ 2157565 lipJ 5213011 lipJ Mycobacterium tuberculosis H37Ra lignin peroxidase LipJ YP_001283231.1 2156177 R 419947 CDS YP_001283232.1 148661709 5213012 2157594..2158886 1 NC_009525.1 competence damage-inducible protein A 2158886 cinA 5213012 cinA Mycobacterium tuberculosis H37Ra competence damage-inducible protein A YP_001283232.1 2157594 D 419947 CDS YP_001283233.1 148661710 5213013 complement(2158938..2160206) 1 NC_009525.1 sialic acid-transport integral membrane protein NanT 2160206 nanT 5213013 nanT Mycobacterium tuberculosis H37Ra sialic acid-transport integral membrane protein NanT YP_001283233.1 2158938 R 419947 CDS YP_001283234.1 148661711 5213014 2160296..2160700 1 NC_009525.1 hypothetical protein 2160700 5213014 MRA_1914 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283234.1 2160296 D 419947 CDS YP_001283235.1 148661712 5214408 2160886..2161317 1 NC_009525.1 hypothetical protein 2161317 5214408 MRA_1915 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283235.1 2160886 D 419947 CDS YP_001283236.1 148661713 5214409 complement(2161365..2162327) 1 NC_009525.1 D-amino acid oxidase 2162327 aao 5214409 aao Mycobacterium tuberculosis H37Ra D-amino acid oxidase YP_001283236.1 2161365 R 419947 CDS YP_001283237.1 148661714 5214410 complement(2162357..2162827) 1 NC_009525.1 hypothetical protein 2162827 5214410 MRA_1917 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283237.1 2162357 R 419947 CDS YP_001283238.1 148661715 5214411 complement(2163167..2163814) 1 NC_009525.1 hypothetical protein 2163814 5214411 MRA_1918 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283238.1 2163167 R 419947 CDS YP_001283239.1 148661716 5214412 complement(2163821..2166043) 1 NC_009525.1 catalase-peroxidase 2166043 katG 5214412 katG Mycobacterium tuberculosis H37Ra catalase-peroxidase YP_001283239.1 2163821 R 419947 CDS YP_001283240.1 148661717 5214413 complement(2166081..2166533) 1 NC_009525.1 ferric uptake regulation protein FurA 2166533 furA 5214413 furA Mycobacterium tuberculosis H37Ra ferric uptake regulation protein FurA YP_001283240.1 2166081 R 419947 CDS YP_001283241.1 148661718 5214414 complement(2166638..2167231) 1 NC_009525.1 phosphatidylethanolamine-binding protein 2167231 5214414 MRA_1921 Mycobacterium tuberculosis H37Ra phosphatidylethanolamine-binding protein YP_001283241.1 2166638 R 419947 CDS YP_001283242.1 148661719 5214415 complement(2167314..2167919) 1 NC_009525.1 lipoprotein LppC 2167919 lppC 5214415 lppC Mycobacterium tuberculosis H37Ra lipoprotein LppC YP_001283242.1 2167314 R 419947 CDS YP_001283243.1 148661720 5213408 complement(2168019..2169023) 1 NC_009525.1 oxidoreductase FadB5 2169023 fadB5 5213408 fadB5 Mycobacterium tuberculosis H37Ra oxidoreductase FadB5 YP_001283243.1 2168019 R 419947 CDS YP_001283244.1 148661721 5213409 2169123..2169875 1 NC_009525.1 hypothetical protein 2169875 5213409 MRA_1924 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283244.1 2169123 D 419947 CDS YP_001283245.1 148661722 5213410 complement(2169853..2170260) 1 NC_009525.1 hypothetical protein 2170260 5213410 MRA_1925 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283245.1 2169853 R 419947 CDS YP_001283246.1 148661723 5213411 2170395..2171498 1 NC_009525.1 isocitrate lyase AceAa 2171498 aceAa 5213411 aceAa Mycobacterium tuberculosis H37Ra isocitrate lyase AceAa YP_001283246.1 2170395 D 419947 CDS YP_001283247.1 148661724 5213412 2171498..2172694 1 NC_009525.1 isocitrate lyase AceAb 2172694 aceAb 5213412 aceAb Mycobacterium tuberculosis H37Ra isocitrate lyase AceAb YP_001283247.1 2171498 D 419947 CDS YP_001283248.1 148661725 5213413 complement(2172864..2177243) 1 NC_009525.1 PPE family protein 2177243 5213413 MRA_1928 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283248.1 2172864 R 419947 CDS YP_001283249.1 148661726 5213414 complement(2177581..2180544) 1 NC_009525.1 PPE family protein 2180544 5213414 MRA_1929 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283249.1 2177581 R 419947 CDS YP_001283250.1 148661727 5213415 complement(2180993..2181457) 1 NC_009525.1 hypothetical protein 2181457 5213415 MRA_1930 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283250.1 2180993 R 419947 CDS YP_001283251.1 148661728 5213269 2181555..2182418 1 NC_009525.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 2182418 5213269 MRA_1931 Mycobacterium tuberculosis H37Ra 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001283251.1 2181555 D 419947 CDS YP_001283252.1 148661729 5213270 complement(2182456..2183727) 1 NC_009525.1 lipoprotein LppF 2183727 lppF 5213270 lppF Mycobacterium tuberculosis H37Ra lipoprotein LppF YP_001283252.1 2182456 R 419947 CDS YP_001283253.1 148661730 5213271 2183999..2185114 1 NC_009525.1 peptidase 2185114 5213271 MRA_1933 Mycobacterium tuberculosis H37Ra peptidase YP_001283253.1 2183999 D 419947 CDS YP_001283254.1 148661731 5213272 2185105..2186445 1 NC_009525.1 lipase LipD 2186445 lipD 5213272 lipD Mycobacterium tuberculosis H37Ra lipase LipD YP_001283254.1 2185105 D 419947 CDS YP_001283255.1 148661732 5213273 complement(2186482..2186862) 1 NC_009525.1 hypothetical protein 2186862 5213273 MRA_1935 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283255.1 2186482 R 419947 CDS YP_001283256.1 148661733 5213274 2187019..2188881 1 NC_009525.1 activates fatty acids by binding to coenzyme A; fatty-acid--CoA ligase 2188881 fadD31 5213274 fadD31 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001283256.1 2187019 D 419947 CDS YP_001283257.1 148661734 5213275 complement(2188889..2189368) 1 NC_009525.1 hypothetical protein 2189368 mpt63 5213275 mpt63 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283257.1 2188889 R 419947 CDS YP_001283258.1 148661735 5213276 2189605..2190378 1 NC_009525.1 hypothetical protein 2190378 5213276 MRA_1938 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283258.1 2189605 D 419947 CDS YP_001283259.1 148661736 5213776 complement(2190382..2191149) 1 NC_009525.1 short chain dehydrogenase 2191149 5213776 MRA_1939 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001283259.1 2190382 R 419947 CDS YP_001283260.1 148661737 5213777 complement(2191194..2191805) 1 NC_009525.1 hypothetical protein 2191805 5213777 MRA_1940 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283260.1 2191194 R 419947 CDS YP_001283261.1 148661738 5213778 complement(2191817..2192341) 1 NC_009525.1 hypothetical protein 2192341 5213778 MRA_1940A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283261.1 2191817 R 419947 CDS YP_001283262.1 148661739 5213779 complement(2192359..2193138) 1 NC_009525.1 transcriptional regulatory protein 2193138 5213779 MRA_1941 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283262.1 2192359 R 419947 CDS YP_001283263.1 148661740 5213780 2193271..2193768 1 NC_009525.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 2193768 tpx 5213780 tpx Mycobacterium tuberculosis H37Ra thiol peroxidase YP_001283263.1 2193271 D 419947 CDS YP_001283264.1 148661741 5213781 complement(2193765..2194856) 1 NC_009525.1 acyl-CoA dehydrogenase 2194856 fadE18 5213781 fadE18 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001283264.1 2193765 R 419947 CDS YP_001283265.1 148661742 5213782 complement(2194858..2196087) 1 NC_009525.1 acyl-CoA dehydrogenase 2196087 fadE17 5213782 fadE17 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001283265.1 2194858 R 419947 CDS YP_001283266.1 148661743 5213783 complement(2196102..2197058) 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2197058 echA13 5213783 echA13 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001283266.1 2196102 R 419947 CDS YP_001283267.1 148661744 5215031 2197283..2198392 1 NC_009525.1 monooxygenase 2198392 5215031 MRA_1946 Mycobacterium tuberculosis H37Ra monooxygenase YP_001283267.1 2197283 D 419947 CDS YP_001283268.1 148661745 5215032 2198395..2200914 1 NC_009525.1 oxygenase 2200914 5215032 MRA_1947 Mycobacterium tuberculosis H37Ra oxygenase YP_001283268.1 2198395 D 419947 CDS YP_001283269.1 148661746 5215033 2200926..2201996 1 NC_009525.1 epoxide hydrolase 2201996 ephB 5215033 ephB Mycobacterium tuberculosis H37Ra epoxide hydrolase YP_001283269.1 2200926 D 419947 CDS YP_001283270.1 148661747 5215034 2201993..2202508 1 NC_009525.1 dimerase 2202508 5215034 MRA_1949 Mycobacterium tuberculosis H37Ra dimerase YP_001283270.1 2201993 D 419947 CDS YP_001283271.1 148661748 5215035 2202505..2203566 1 NC_009525.1 3,4-dihydroxy-2-butanone-4-phosphate synthase 2203566 ribA1 5215035 ribA1 Mycobacterium tuberculosis H37Ra 3,4-dihydroxy-2-butanone-4-phosphate synthase YP_001283271.1 2202505 D 419947 CDS YP_001283272.1 148661749 5215036 2203563..2204333 1 NC_009525.1 short-chain type dehydrogenase/reductase 2204333 5215036 MRA_1951 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001283272.1 2203563 D 419947 CDS YP_001283273.1 148661750 5215037 complement(2204543..2204872) 1 NC_009525.1 hypothetical protein 2204872 5215037 MRA_1952 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283273.1 2204543 R 419947 CDS YP_001283274.1 148661751 5215038 complement(2204869..2205246) 1 NC_009525.1 hypothetical protein 2205246 5215038 MRA_1953 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283274.1 2204869 R 419947 CDS YP_001283275.1 148661752 5215596 complement(2205243..2205833) 1 NC_009525.1 hypothetical protein 2205833 5215596 MRA_1954 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283275.1 2205243 R 419947 CDS YP_001283276.1 148661753 5215597 2205804..2207252 1 NC_009525.1 hypothetical protein 2207252 5215597 MRA_1955 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283276.1 2205804 D 419947 CDS YP_001283277.1 148661754 5215598 complement(2207407..2207859) 1 NC_009525.1 lipoprotein LppG 2207859 lppG 5215598 lppG Mycobacterium tuberculosis H37Ra lipoprotein LppG YP_001283277.1 2207407 R 419947 CDS YP_001283278.1 148661755 5215599 2207923..2208324 1 NC_009525.1 hypothetical protein 2208324 5215599 MRA_1957 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283278.1 2207923 D 419947 CDS YP_001283279.1 148661756 5215600 complement(2208613..2208963) 1 NC_009525.1 hypothetical protein 2208963 5215600 MRA_1958 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283279.1 2208613 R 419947 CDS YP_001283280.1 148661757 5215601 complement(2208974..2209876) 1 NC_009525.1 hypothetical protein 2209876 5215601 MRA_1959 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283280.1 2208974 R 419947 CDS YP_001283281.1 148661758 5215602 complement(2209897..2210088) 1 NC_009525.1 hypothetical protein 2210088 5215602 MRA_1960 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283281.1 2209897 R 419947 CDS YP_001283282.1 148661759 5215603 complement(2210089..2210385) 1 NC_009525.1 hypothetical protein 2210385 5215603 MRA_1961 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283282.1 2210089 R 419947 CDS YP_001283283.1 148661760 5212072 2210625..2210840 1 NC_009525.1 hypothetical protein 2210840 5212072 MRA_1962 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283283.1 2210625 D 419947 CDS YP_001283284.1 148661761 5212073 2210837..2211148 1 NC_009525.1 hypothetical protein 2211148 5212073 MRA_1963 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283284.1 2210837 D 419947 CDS YP_001283285.1 148661762 5212074 2211483..2211995 1 NC_009525.1 hypothetical protein 2211995 5212074 MRA_1964 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283285.1 2211483 D 419947 CDS YP_001283286.1 148661763 5212075 2212037..2212486 1 NC_009525.1 transcriptional regulatory protein 2212486 5212075 MRA_1965 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283286.1 2212037 D 419947 CDS YP_001283287.1 148661764 5212076 2212483..2213028 1 NC_009525.1 hypothetical protein 2213028 5212076 MRA_1966 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283287.1 2212483 D 419947 CDS YP_001283288.1 148661765 5212077 complement(2212917..2213531) 1 NC_009525.1 hypothetical protein 2213531 5212077 MRA_1967 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283288.1 2212917 R 419947 CDS YP_001283289.1 148661766 5212078 complement(2213580..2213876) 1 NC_009525.1 hypothetical protein 2213876 5212078 MRA_1968 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283289.1 2213580 R 419947 CDS YP_001283290.1 148661767 5212079 complement(2213873..2214124) 1 NC_009525.1 hypothetical protein 2214124 5212079 MRA_1969 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283290.1 2213873 R 419947 CDS YP_001283291.1 148661768 5211939 2214111..2214605 1 NC_009525.1 hypothetical protein 2214605 5211939 MRA_1970 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283291.1 2214111 D 419947 CDS YP_001283292.1 148661769 5211940 complement(2214765..2215172) 1 NC_009525.1 hypothetical protein 2215172 5211940 MRA_1971 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283292.1 2214765 R 419947 CDS YP_001283293.1 148661770 5211941 complement(2215176..2215448) 1 NC_009525.1 hypothetical protein 2215448 5211941 MRA_1972 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283293.1 2215176 R 419947 CDS YP_001283294.1 148661771 5211942 complement(2215481..2216701) 1 NC_009525.1 TetR family transcriptional regulator 2216701 mce3R 5211942 mce3R Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001283294.1 2215481 R 419947 CDS YP_001283295.1 148661772 5211943 2216849..2217106 1 NC_009525.1 hypothetical protein 2217106 5211943 MRA_1974 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283295.1 2216849 D 419947 CDS YP_001283296.1 148661773 5211944 2217600..2218397 1 NC_009525.1 hypothetical protein 2218397 yrbE3A 5211944 yrbE3A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283296.1 2217600 D 419947 CDS YP_001283297.1 148661774 5211945 2218407..2219222 1 NC_009525.1 hypothetical protein 2219222 yrbE3B 5211945 yrbE3B Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283297.1 2218407 D 419947 CDS YP_001283298.1 148661775 5211946 2219227..2220504 1 NC_009525.1 MCE-family protein Mce3A 2220504 mce3A 5211946 mce3A Mycobacterium tuberculosis H37Ra MCE-family protein Mce3A YP_001283298.1 2219227 D 419947 CDS YP_001283299.1 148661776 5212999 2220501..2221529 1 NC_009525.1 MCE-family protein Mce3B 2221529 mce3B 5212999 mce3B Mycobacterium tuberculosis H37Ra MCE-family protein Mce3B YP_001283299.1 2220501 D 419947 CDS YP_001283300.1 148661777 5213000 2221526..2222758 1 NC_009525.1 MCE-family protein Mce3C 2222758 mce3C 5213000 mce3C Mycobacterium tuberculosis H37Ra MCE-family protein Mce3C YP_001283300.1 2221526 D 419947 CDS YP_001283301.1 148661778 5213001 2222755..2224026 1 NC_009525.1 MCE-family protein Mce3D 2224026 mce3D 5213001 mce3D Mycobacterium tuberculosis H37Ra MCE-family protein Mce3D YP_001283301.1 2222755 D 419947 CDS YP_001283302.1 148661779 5213002 2224023..2225156 1 NC_009525.1 MCE family lipoprotein LprM 2225156 lprM 5213002 lprM Mycobacterium tuberculosis H37Ra MCE family lipoprotein LprM YP_001283302.1 2224023 D 419947 CDS YP_001283303.1 148661780 5213003 2225157..2226470 1 NC_009525.1 MCE-family protein Mce3F 2226470 mce3F 5213003 mce3F Mycobacterium tuberculosis H37Ra MCE-family protein Mce3F YP_001283303.1 2225157 D 419947 CDS YP_001283304.1 148661781 5213004 2226492..2227067 1 NC_009525.1 Mce associated membrane protein 2227067 5213004 MRA_1983 Mycobacterium tuberculosis H37Ra Mce associated membrane protein YP_001283304.1 2226492 D 419947 CDS YP_001283305.1 148661782 5213005 2227064..2227546 1 NC_009525.1 Mce associated membrane protein 2227546 5213005 MRA_1984 Mycobacterium tuberculosis H37Ra Mce associated membrane protein YP_001283305.1 2227064 D 419947 CDS YP_001283306.1 148661783 5213006 2227559..2227936 1 NC_009525.1 hypothetical protein 2227936 5213006 MRA_1985 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283306.1 2227559 D 419947 CDS YP_001283307.1 148661784 5212553 2227952..2228617 1 NC_009525.1 hypothetical protein 2228617 5212553 MRA_1986 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283307.1 2227952 D 419947 CDS YP_001283308.1 148661785 5212554 complement(2228744..2229151) 1 NC_009525.1 hypothetical protein 2229151 5212554 MRA_1987 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283308.1 2228744 R 419947 CDS YP_001283309.1 148661786 5212555 2229654..2230700 1 NC_009525.1 hypothetical protein 2230700 5212555 MRA_1988 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283309.1 2229654 D 419947 CDS YP_001283310.1 148661787 5212556 2230808..2231656 1 NC_009525.1 hypothetical protein 2231656 5212556 MRA_1989 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283310.1 2230808 D 419947 CDS YP_001283311.1 148661788 5212557 complement(2231619..2233064) 1 NC_009525.1 amino acid permease 2233064 5212557 MRA_1990 Mycobacterium tuberculosis H37Ra amino acid permease YP_001283311.1 2231619 R 419947 CDS YP_001283312.1 148661789 5212558 complement(2233243..2233929) 1 NC_009525.1 hypothetical protein 2233929 mpt64 5212558 mpt64 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283312.1 2233243 R 419947 CDS YP_001283313.1 148661790 5212559 complement(2234120..2235088) 1 NC_009525.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2235088 nrdF1 5212559 nrdF1 Mycobacterium tuberculosis H37Ra ribonucleotide-diphosphate reductase subunit beta YP_001283313.1 2234120 R 419947 CDS YP_001283314.1 148661791 5212560 complement(2235313..2235732) 1 NC_009525.1 hypothetical protein 2235732 5212560 MRA_1993 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283314.1 2235313 R 419947 CDS YP_001283315.1 148661792 5213599 complement(2235741..2236001) 1 NC_009525.1 hypothetical protein 2236001 5213599 MRA_1994 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283315.1 2235741 R 419947 CDS YP_001283316.1 148661793 5213600 2236144..2237820 1 NC_009525.1 PE-PGRS family protein 2237820 5213600 MRA_1995 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283316.1 2236144 D 419947 CDS YP_001283317.1 148661794 5213601 complement(2237808..2238461) 1 NC_009525.1 cutinase precursor Cfp21 2238461 cfp21 5213601 cfp21 Mycobacterium tuberculosis H37Ra cutinase precursor Cfp21 YP_001283317.1 2237808 R 419947 CDS YP_001283318.1 148661795 5213602 2238576..2238806 1 NC_009525.1 PE-PGRS family protein 2238806 5213602 MRA_1997 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283318.1 2238576 D 419947 CDS YP_001283319.1 148661796 5213603 complement(2238891..2239802) 1 NC_009525.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 2239802 5213603 MRA_1998 Mycobacterium tuberculosis H37Ra chromosome replication initiation inhibitor protein YP_001283319.1 2238891 R 419947 CDS YP_001283320.1 148661797 5213604 2239911..2240510 1 NC_009525.1 integral membrane protein 2240510 5213604 MRA_1999 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283320.1 2239911 D 419947 CDS YP_001283321.1 148661798 5213605 2240926..2241354 1 NC_009525.1 chitinase 2241354 5213605 MRA_2000 Mycobacterium tuberculosis H37Ra chitinase YP_001283321.1 2240926 D 419947 CDS YP_001283322.1 148661799 5213606 2241580..2242119 1 NC_009525.1 rRNA adenine N-6-methyltransferase 2242119 5213606 MRA_2001 Mycobacterium tuberculosis H37Ra rRNA adenine N-6-methyltransferase YP_001283322.1 2241580 D 419947 CDS YP_001283323.1 148661800 5214669 2242299..2242571 1 NC_009525.1 hypothetical protein 2242571 5214669 MRA_2002 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283323.1 2242299 D 419947 CDS YP_001283324.1 148661801 5214670 complement(2242639..2243199) 1 NC_009525.1 hypothetical protein 2243199 5214670 MRA_2003 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283324.1 2242639 R 419947 CDS YP_001283325.1 148661802 5214671 complement(2243196..2243537) 1 NC_009525.1 transcriptional regulatory protein 2243537 5214671 MRA_2004 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283325.1 2243196 R 419947 CDS YP_001283326.1 148661803 5214672 complement(2243781..2244116) 1 NC_009525.1 dehydrogenase 2244116 5214672 MRA_2005 Mycobacterium tuberculosis H37Ra dehydrogenase YP_001283326.1 2243781 R 419947 CDS YP_001283327.1 148661804 5214673 complement(2244205..2244549) 1 NC_009525.1 hypothetical protein 2244549 5214673 MRA_2006 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283327.1 2244205 R 419947 CDS YP_001283328.1 148661805 5214674 complement(2244543..2244791) 1 NC_009525.1 hypothetical protein 2244791 5214674 MRA_2007 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283328.1 2244543 R 419947 CDS YP_001283329.1 148661806 5214675 complement(2244891..2247206) 1 NC_009525.1 metal cation transporting P-type ATPase CtpG 2247206 ctpG 5214675 ctpG Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpG YP_001283329.1 2244891 R 419947 CDS YP_001283330.1 148661807 5214676 complement(2247203..2247475) 1 NC_009525.1 hypothetical protein 2247475 5214676 MRA_2009 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283330.1 2247203 R 419947 CDS YP_001283331.1 148661808 5214846 complement(2247528..2247884) 1 NC_009525.1 transcription regulator ArsR 2247884 5214846 MRA_2010 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001283331.1 2247528 R 419947 CDS YP_001283332.1 148661809 5214847 2248041..2248808 1 NC_009525.1 hypothetical protein 2248808 5214847 MRA_2011 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283332.1 2248041 D 419947 CDS YP_001283333.1 148661810 5214848 2248904..2249857 1 NC_009525.1 hypothetical protein 2249857 5214848 MRA_2012 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283333.1 2248904 D 419947 CDS YP_001283334.1 148661811 5214849 2250059..2252776 1 NC_009525.1 metal cation transporting P-type ATPase CtpF 2252776 ctpF 5214849 ctpF Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpF YP_001283334.1 2250059 D 419947 CDS YP_001283335.1 148661812 5214850 complement(2252845..2253621) 1 NC_009525.1 hypothetical protein 2253621 5214850 MRA_2014 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283335.1 2252845 R 419947 CDS YP_001283336.1 148661813 5214851 complement(2253716..2255038) 1 NC_009525.1 integral membrane protein 2255038 5214851 MRA_2015 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283336.1 2253716 R 419947 CDS YP_001283337.1 148661814 5214852 2255109..2256722 1 NC_009525.1 hypothetical protein 2256722 5214852 MRA_2016 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283337.1 2255109 D 419947 CDS YP_001283338.1 148661815 5214853 2256732..2257484 1 NC_009525.1 hypothetical protein 2257484 5214853 MRA_2017 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283338.1 2256732 D 419947 CDS YP_001283339.1 148661816 5211836 2257560..2258342 1 NC_009525.1 20-beta-hydroxysteroid dehydrogenase FabG3 2258342 fabG3-1 5211836 fabG3-1 Mycobacterium tuberculosis H37Ra 20-beta-hydroxysteroid dehydrogenase FabG3 YP_001283339.1 2257560 D 419947 CDS YP_001283340.1 148661817 5211837 complement(2258463..2259320) 1 NC_009525.1 hypothetical protein 2259320 5211837 MRA_2019 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283340.1 2258463 R 419947 CDS YP_001283341.1 148661818 5211838 complement(2259378..2260874) 1 NC_009525.1 hypothetical protein 2260874 5211838 MRA_2020 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283341.1 2259378 R 419947 CDS YP_001283342.1 148661819 5211839 complement(2260896..2261783) 1 NC_009525.1 hypothetical protein 2261783 5211839 MRA_2021 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283342.1 2260896 R 419947 CDS YP_001283343.1 148661820 5211840 2261902..2265885 1 NC_009525.1 glycosyl hydrolase 2265885 otsB1 5211840 otsB1 Mycobacterium tuberculosis H37Ra glycosyl hydrolase YP_001283343.1 2261902 D 419947 CDS YP_001283344.1 148661821 5211841 complement(2265984..2266328) 1 NC_009525.1 ferredoxin FdxA 2266328 fdxA 5211841 fdxA Mycobacterium tuberculosis H37Ra ferredoxin FdxA YP_001283344.1 2265984 R 419947 CDS YP_001283345.1 148661822 5211842 complement(2266517..2267842) 1 NC_009525.1 hypothetical protein 2267842 5211842 MRA_2024 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283345.1 2266517 R 419947 CDS YP_001283346.1 148661823 5211843 2267930..2268172 1 NC_009525.1 hypothetical protein 2268172 5211843 MRA_2025 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283346.1 2267930 D 419947 CDS YP_001283347.1 148661824 5213162 2268173..2268571 1 NC_009525.1 hypothetical protein 2268571 5213162 MRA_2026 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283347.1 2268173 D 419947 CDS YP_001283348.1 148661825 5213163 complement(2268754..2269185) 1 NC_009525.1 hypothetical protein 2269185 5213163 MRA_2027 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283348.1 2268754 R 419947 CDS YP_001283349.1 148661826 5213164 2269226..2269720 1 NC_009525.1 hypothetical protein 2269720 5213164 MRA_2028 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283349.1 2269226 D 419947 CDS YP_001283350.1 148661827 5213165 2270565..2271044 1 NC_009525.1 transposase 2271044 5213165 MRA_2029 Mycobacterium tuberculosis H37Ra transposase YP_001283350.1 2270565 D 419947 CDS YP_001283351.1 148661828 5213166 2270998..2271588 1 NC_009525.1 transposase 2271588 5213166 MRA_2030 Mycobacterium tuberculosis H37Ra transposase YP_001283351.1 2270998 D 419947 CDS YP_001283352.1 148661829 5213167 complement(2271716..2272972) 1 NC_009525.1 hypothetical protein 2272972 5213167 MRA_2031 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283352.1 2271716 R 419947 CDS YP_001283353.1 148661830 5213168 2273326..2273901 1 NC_009525.1 hypothetical protein 2273901 5213168 MRA_2032 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283353.1 2273326 D 419947 CDS YP_001283354.1 148661831 5213169 2273898..2274938 1 NC_009525.1 transcriptional regulatory protein 2274938 5213169 MRA_2033 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283354.1 2273898 D 419947 CDS YP_001283355.1 148661832 5212977 2275180..2275899 1 NC_009525.1 hypothetical protein 2275899 5212977 MRA_2034 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283355.1 2275180 D 419947 CDS YP_001283356.1 148661833 5212978 2275889..2276305 1 NC_009525.1 hypothetical protein 2276305 5212978 MRA_2035 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283356.1 2275889 D 419947 CDS YP_001283357.1 148661834 5212979 complement(2276321..2276620) 1 NC_009525.1 hypothetical protein 2276620 5212979 MRA_2036 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283357.1 2276321 R 419947 CDS YP_001283358.1 148661835 5212980 complement(2276705..2277010) 1 NC_009525.1 transcriptional regulatory protein 2277010 5212980 MRA_2037 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283358.1 2276705 R 419947 CDS YP_001283359.1 148661836 5212981 complement(2277019..2277624) 1 NC_009525.1 hypothetical protein 2277624 5212981 MRA_2038 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283359.1 2277019 R 419947 CDS YP_001283360.1 148661837 5212982 complement(2277649..2278008) 1 NC_009525.1 hypothetical protein 2278008 5212982 MRA_2038A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283360.1 2277649 R 419947 CDS YP_001283361.1 148661838 5212983 complement(2278593..2280140) 1 NC_009525.1 hypothetical protein 2280140 5212983 MRA_2039 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283361.1 2278593 R 419947 CDS YP_001283362.1 148661839 5212984 complement(2280650..2281648) 1 NC_009525.1 cation efflux system protein 2281648 5212984 MRA_2040 Mycobacterium tuberculosis H37Ra cation efflux system protein YP_001283362.1 2280650 R 419947 CDS YP_001283363.1 148661840 5212335 complement(2281763..2282647) 1 NC_009525.1 hypothetical protein 2282647 5212335 MRA_2041 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283363.1 2281763 R 419947 CDS YP_001283364.1 148661841 5212336 complement(2282687..2284408) 1 NC_009525.1 histidine kinase response regulator 2284408 5212336 MRA_2042 Mycobacterium tuberculosis H37Ra histidine kinase response regulator YP_001283364.1 2282687 R 419947 CDS YP_001283365.1 148661842 5212337 complement(2284469..2285308) 1 NC_009525.1 hypothetical protein 2285308 5212337 MRA_2043 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283365.1 2284469 R 419947 CDS YP_001283366.1 148661843 5212338 complement(2285305..2286324) 1 NC_009525.1 phosphofructokinase PfkB 2286324 pfkB 5212338 pfkB Mycobacterium tuberculosis H37Ra phosphofructokinase PfkB YP_001283366.1 2285305 R 419947 CDS YP_001283367.1 148661844 5212339 complement(2286341..2288386) 1 NC_009525.1 hypothetical protein 2288386 5212339 MRA_2045 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283367.1 2286341 R 419947 CDS YP_001283368.1 148661845 5212340 complement(2288398..2288832) 1 NC_009525.1 antigen Hsp20 2288832 hspX 5212340 hspX Mycobacterium tuberculosis H37Ra antigen Hsp20 YP_001283368.1 2288398 R 419947 CDS YP_001283369.1 148661846 5212341 2289029..2290024 1 NC_009525.1 hypothetical protein 2290024 acg 5212341 acg Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283369.1 2289029 D 419947 CDS YP_001283370.1 148661847 5212342 complement(2290140..2290982) 1 NC_009525.1 hypothetical protein 2290982 5212342 MRA_2048 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283370.1 2290140 R 419947 CDS YP_001283371.1 148661848 5215604 2291194..2291517 1 NC_009525.1 transcription regulator ArsR 2291517 5215604 MRA_2049 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001283371.1 2291194 D 419947 CDS YP_001283372.1 148661849 5215605 2291514..2292002 1 NC_009525.1 hypothetical protein 2292002 5215605 MRA_2050 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283372.1 2291514 D 419947 CDS YP_001283373.1 148661850 5215606 2291999..2292640 1 NC_009525.1 hypothetical protein 2292640 5215606 MRA_2051 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283373.1 2291999 D 419947 CDS YP_001283374.1 148661851 5215607 complement(2292647..2293621) 1 NC_009525.1 hypothetical protein 2293621 5215607 MRA_2052 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283374.1 2292647 R 419947 CDS YP_001283375.1 148661852 5215608 complement(2293623..2294696) 1 NC_009525.1 sugar ABC transporter ATP-binding protein 2294696 5215608 MRA_2053 Mycobacterium tuberculosis H37Ra sugar ABC transporter ATP-binding protein YP_001283375.1 2293623 R 419947 CDS YP_001283376.1 148661853 5215609 complement(2294699..2295541) 1 NC_009525.1 sugar ABC transporter permease 2295541 5215609 MRA_2054 Mycobacterium tuberculosis H37Ra sugar ABC transporter permease YP_001283376.1 2294699 R 419947 CDS YP_001283377.1 148661854 5215610 complement(2295528..2296430) 1 NC_009525.1 sugar ABC transporter permease 2296430 5215610 MRA_2055 Mycobacterium tuberculosis H37Ra sugar ABC transporter permease YP_001283377.1 2295528 R 419947 CDS YP_001283378.1 148661855 5215611 complement(2296427..2297746) 1 NC_009525.1 sugar-binding lipoprotein 2297746 5215611 MRA_2056 Mycobacterium tuberculosis H37Ra sugar-binding lipoprotein YP_001283378.1 2296427 R 419947 CDS YP_001283379.1 148661856 5211921 complement(2297784..2298581) 1 NC_009525.1 hypothetical protein 2298581 5211921 MRA_2057 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283379.1 2297784 R 419947 CDS YP_001283380.1 148661857 5211922 complement(2298581..2299141) 1 NC_009525.1 pyrazinamidase/nicotinamidase 2299141 pncA 5211922 pncA Mycobacterium tuberculosis H37Ra pyrazinamidase/nicotinamidase YP_001283380.1 2298581 R 419947 CDS YP_001283381.1 148661858 5211923 complement(2299182..2299499) 1 NC_009525.1 hypothetical protein 2299499 5211923 MRA_2059 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283381.1 2299182 R 419947 CDS YP_001283382.1 148661859 5211924 complement(2299585..2301120) 1 NC_009525.1 carboxylesterase LipT 2301120 lipT 5211924 lipT Mycobacterium tuberculosis H37Ra carboxylesterase LipT YP_001283382.1 2299585 R 419947 CDS YP_001283383.1 148661860 5211925 2301169..2301825 1 NC_009525.1 lipoprotein LppI 2301825 lppI 5211925 lppI Mycobacterium tuberculosis H37Ra lipoprotein LppI YP_001283383.1 2301169 D 419947 CDS YP_001283384.1 148661861 5211926 complement(2301862..2304426) 1 NC_009525.1 hypothetical protein 2304426 5211926 MRA_2062 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283384.1 2301862 R 419947 CDS YP_001283385.1 148661862 5211927 complement(2304431..2316886) 1 NC_009525.1 polyketide synthase 2316886 pks12 5211927 pks12 Mycobacterium tuberculosis H37Ra polyketide synthase YP_001283385.1 2304431 R 419947 CDS YP_001283386.1 148661863 5211928 complement(2317193..2317417) 1 NC_009525.1 hypothetical protein 2317417 5211928 MRA_2064 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283386.1 2317193 R 419947 CDS YP_001283387.1 148661864 5213154 2317721..2318056 1 NC_009525.1 hypothetical protein 2318056 5213154 MRA_2065 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283387.1 2317721 D 419947 CDS YP_001283388.1 148661865 5213155 complement(2318031..2320655) 1 NC_009525.1 polyprenol-monophosphomannose synthase Ppm1 2320655 ppm1 5213155 ppm1 Mycobacterium tuberculosis H37Ra polyprenol-monophosphomannose synthase Ppm1 YP_001283388.1 2318031 R 419947 CDS YP_001283389.1 148661866 5213156 complement(2320813..2322417) 1 NC_009525.1 hypothetical protein 2322417 5213156 MRA_2067 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283389.1 2320813 R 419947 CDS YP_001283390.1 148661867 5213157 complement(2322422..2322949) 1 NC_009525.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 2322949 fxsA 5213157 fxsA Mycobacterium tuberculosis H37Ra FxsA YP_001283390.1 2322422 R 419947 CDS YP_001283391.1 148661868 5213158 2323025..2323738 1 NC_009525.1 hypothetical protein 2323738 5213158 MRA_2069 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283391.1 2323025 D 419947 CDS YP_001283392.1 148661869 5213159 complement(2323987..2324253) 1 NC_009525.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 2324253 rpsR2 5213159 rpsR2 Mycobacterium tuberculosis H37Ra 30S ribosomal protein S18 YP_001283392.1 2323987 R 419947 CDS YP_001283393.1 148661870 5213160 complement(2324254..2324559) 1 NC_009525.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 2324559 rpsN 5213160 rpsN Mycobacterium tuberculosis H37Ra 30S ribosomal protein S14 YP_001283393.1 2324254 R 419947 CDS YP_001283394.1 148661871 5213161 complement(2324561..2324725) 1 NC_009525.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2324725 rpmG 5213161 rpmG Mycobacterium tuberculosis H37Ra 50S ribosomal protein L33 YP_001283394.1 2324561 R 419947 CDS YP_001283395.1 148661872 5212830 complement(2324725..2324961) 1 NC_009525.1 required for 70S ribosome assembly; 50S ribosomal protein L28 2324961 rpmB 5212830 rpmB Mycobacterium tuberculosis H37Ra 50S ribosomal protein L28 YP_001283395.1 2324725 R 419947 CDS YP_001283396.1 148661873 5212831 2325074..2326609 1 NC_009525.1 hypothetical protein 2326609 5212831 MRA_2074 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283396.1 2325074 D 419947 CDS YP_001283397.1 148661874 5212832 complement(2326581..2326985) 1 NC_009525.1 hypothetical protein 2326985 5212832 MRA_2074A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283397.1 2326581 R 419947 CDS YP_001283398.1 148661875 5212833 complement(2327069..2330653) 1 NC_009525.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 2330653 cobN 5212833 cobN Mycobacterium tuberculosis H37Ra cobaltochelatase subunit CobN YP_001283398.1 2327069 R 419947 CDS YP_001283399.1 148661876 5212834 2330731..2330964 1 NC_009525.1 hypothetical protein 2330964 5212834 MRA_2076 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283399.1 2330731 D 419947 CDS YP_001283400.1 148661877 5212835 2330957..2331367 1 NC_009525.1 hypothetical protein 2331367 5212835 MRA_2077 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283400.1 2330957 D 419947 CDS YP_001283401.1 148661878 5212836 2331351..2332442 1 NC_009525.1 CobG-related protein 2332442 cobG 5212836 cobG Mycobacterium tuberculosis H37Ra CobG-related protein YP_001283401.1 2331351 D 419947 CDS YP_001283402.1 148661879 5212837 2332452..2333078 1 NC_009525.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase 2333078 cobH 5212837 cobH Mycobacterium tuberculosis H37Ra precorrin-8X methylmutase YP_001283402.1 2332452 D 419947 CDS YP_001283403.1 148661880 5212561 2333075..2334601 1 NC_009525.1 S-adenosyl-L-methionine--precorrin-2 methyltransferase/precorrin-3b c17-methyltransferase 2334601 cobI 5212561 cobI Mycobacterium tuberculosis H37Ra S-adenosyl-L-methionine--precorrin-2 methyltransferase/precorrin-3b c17-methyltransferase YP_001283403.1 2333075 D 419947 CDS YP_001283404.1 148661881 5212562 complement(2334547..2335770) 1 NC_009525.1 hypothetical protein 2335770 5212562 MRA_2081 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283404.1 2334547 R 419947 CDS YP_001283405.1 148661882 5212563 complement(2335786..2336709) 1 NC_009525.1 beta-lactamase 2336709 blaC 5212563 blaC Mycobacterium tuberculosis H37Ra beta-lactamase YP_001283405.1 2335786 R 419947 CDS YP_001283406.1 148661883 5212564 2336844..2337401 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigC 2337401 sigC 5212564 sigC Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigC YP_001283406.1 2336844 D 419947 CDS YP_001283407.1 148661884 5212565 complement(2337391..2338125) 1 NC_009525.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 2338125 cobK 5212565 cobK Mycobacterium tuberculosis H37Ra cobalt-precorrin-6x reductase YP_001283407.1 2337391 R 419947 CDS YP_001283408.1 148661885 5212566 complement(2338122..2338877) 1 NC_009525.1 precorrin-4 C11-methyltransferase 2338877 cobM 5212566 cobM Mycobacterium tuberculosis H37Ra precorrin-4 C11-methyltransferase YP_001283408.1 2338122 R 419947 CDS YP_001283409.1 148661886 5212567 complement(2338874..2340046) 1 NC_009525.1 precorrin-6y c5,15-methyltransferase 2340046 cobL 5212567 cobL Mycobacterium tuberculosis H37Ra precorrin-6y c5,15-methyltransferase YP_001283409.1 2338874 R 419947 CDS YP_001283410.1 148661887 5212568 complement(2340114..2340863) 1 NC_009525.1 short-chain type dehydrogenase/reductase 2340863 5212568 MRA_2087 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001283410.1 2340114 R 419947 CDS YP_001283411.1 148661888 5214998 2340893..2341306 1 NC_009525.1 hypothetical protein 2341306 5214998 MRA_2088 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283411.1 2340893 D 419947 CDS YP_001283412.1 148661889 5214999 complement(2341316..2342779) 1 NC_009525.1 hypothetical protein 2342779 5214999 MRA_2089 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283412.1 2341316 R 419947 CDS YP_001283413.1 148661890 5215000 complement(2342937..2343188) 1 NC_009525.1 hypothetical protein 2343188 5215000 MRA_2090 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283413.1 2342937 R 419947 CDS YP_001283414.1 148661891 5215001 complement(2343223..2344194) 1 NC_009525.1 transmembrane protein 2344194 5215001 MRA_2091 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283414.1 2343223 R 419947 CDS YP_001283415.1 148661892 5215002 complement(2344195..2344494) 1 NC_009525.1 hypothetical protein 2344494 5215002 MRA_2091A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283415.1 2344195 R 419947 CDS YP_001283416.1 148661893 5215003 2344959..2345273 1 NC_009525.1 hypothetical protein 2345273 5215003 MRA_2092 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283416.1 2344959 D 419947 CDS YP_001283417.1 148661894 5215004 2345255..2347225 1 NC_009525.1 hypothetical protein 2347225 5215004 MRA_2093 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283417.1 2345255 D 419947 CDS YP_001283418.1 148661895 5215005 2347206..2347769 1 NC_009525.1 lipoprotein LppJ 2347769 lppJ 5215005 lppJ Mycobacterium tuberculosis H37Ra lipoprotein LppJ YP_001283418.1 2347206 D 419947 CDS YP_001283419.1 148661896 5215006 2347690..2348088 1 NC_009525.1 hypothetical protein 2348088 5215006 MRA_2095 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283419.1 2347690 D 419947 CDS YP_001283420.1 148661897 5215657 complement(2347965..2348405) 1 NC_009525.1 transmembrane protein 2348405 5215657 MRA_2096 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283420.1 2347965 R 419947 CDS YP_001283421.1 148661898 5215658 2348609..2350774 1 NC_009525.1 hypothetical protein 2350774 5215658 MRA_2098 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283421.1 2348609 D 419947 CDS YP_001283422.1 148661899 5215659 2350771..2351715 1 NC_009525.1 hypothetical protein 2351715 5215659 MRA_2099 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283422.1 2350771 D 419947 CDS YP_001283423.1 148661900 5215660 2351708..2352844 1 NC_009525.1 hypothetical protein 2352844 5215660 MRA_2100 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283423.1 2351708 D 419947 CDS YP_001283424.1 148661901 5215661 2352927..2353232 1 NC_009525.1 transposase 2353232 5215661 MRA_2101 Mycobacterium tuberculosis H37Ra transposase YP_001283424.1 2352927 D 419947 CDS YP_001283425.1 148661902 5215662 2353211..2353816 1 NC_009525.1 hypothetical protein 2353816 5215662 MRA_2102 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283425.1 2353211 D 419947 CDS YP_001283426.1 148661903 5215663 2354311..2356080 1 NC_009525.1 serine/threonine protein kinase 2356080 pknJ 5215663 pknJ Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001283426.1 2354311 D 419947 CDS YP_001283427.1 148661904 5215664 complement(2356097..2357224) 1 NC_009525.1 Xaa-Pro dipeptidase 2357224 pepE 5215664 pepE Mycobacterium tuberculosis H37Ra Xaa-Pro dipeptidase YP_001283427.1 2356097 R 419947 CDS YP_001283428.1 148661905 5215665 2357273..2358454 1 NC_009525.1 5'-3' exonuclease 2358454 5215665 MRA_2105 Mycobacterium tuberculosis H37Ra 5'-3' exonuclease YP_001283428.1 2357273 D 419947 CDS YP_001283429.1 148661906 5215666 complement(2358458..2359192) 1 NC_009525.1 hypothetical protein 2359192 5215666 MRA_2106 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283429.1 2358458 R 419947 CDS YP_001283430.1 148661907 5215667 complement(2359234..2361954) 1 NC_009525.1 ATP-dependent DNA helicase HelY 2361954 helY 5215667 helY Mycobacterium tuberculosis H37Ra ATP-dependent DNA helicase HelY YP_001283430.1 2359234 R 419947 CDS YP_001283431.1 148661908 5215668 complement(2362003..2362929) 1 NC_009525.1 twin arginine-targeting protein translocase TatC 2362929 tatC 5215668 tatC Mycobacterium tuberculosis H37Ra twin arginine-targeting protein translocase TatC YP_001283431.1 2362003 R 419947 CDS YP_001283432.1 148661909 5215669 complement(2362946..2363197) 1 NC_009525.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 2363197 tatA 5215669 tatA Mycobacterium tuberculosis H37Ra twin arginine translocase A YP_001283432.1 2362946 R 419947 CDS YP_001283433.1 148661910 5215670 complement(2363265..2364215) 1 NC_009525.1 hypothetical protein 2364215 5215670 MRA_2110 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283433.1 2363265 R 419947 CDS YP_001283434.1 148661911 5215671 complement(2364212..2365210) 1 NC_009525.1 hypothetical protein 2365210 5215671 MRA_2111 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283434.1 2364212 R 419947 CDS YP_001283435.1 148661912 5215672 complement(2365219..2366577) 1 NC_009525.1 hypothetical protein 2366577 5215672 MRA_2112 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283435.1 2365219 R 419947 CDS YP_001283436.1 148661913 5213125 complement(2366826..2367875) 1 NC_009525.1 PE-PGRS family protein 2367875 5213125 MRA_2113 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283436.1 2366826 R 419947 CDS YP_001283437.1 148661914 5213126 2368291..2369943 1 NC_009525.1 hypothetical protein 2369943 5213126 MRA_2114 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283437.1 2368291 D 419947 CDS YP_001283438.1 148661915 5213127 2370142..2373183 1 NC_009525.1 helicase HelZ 2373183 helZ 5213127 helZ Mycobacterium tuberculosis H37Ra helicase HelZ YP_001283438.1 2370142 D 419947 CDS YP_001283439.1 148661916 5213128 2373293..2374009 1 NC_009525.1 hypothetical protein 2374009 5213128 MRA_2116 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283439.1 2373293 D 419947 CDS YP_001283440.1 148661917 5213129 complement(2373988..2374422) 1 NC_009525.1 hypothetical protein 2374422 5213129 MRA_2117 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283440.1 2373988 R 419947 CDS YP_001283441.1 148661918 5213130 complement(2374429..2374683) 1 NC_009525.1 hypothetical protein 2374683 5213130 MRA_2118 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283441.1 2374429 R 419947 CDS YP_001283442.1 148661919 5213131 complement(2374699..2374956) 1 NC_009525.1 hypothetical protein 2374956 5213131 MRA_2119 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283442.1 2374699 R 419947 CDS YP_001283443.1 148661920 5213132 2375367..2375693 1 NC_009525.1 IS6110 hypothetical protein 2375693 5213132 MRA_2120 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283443.1 2375367 D 419947 CDS YP_001283444.1 148661921 5211993 2375744..2376628 1 NC_009525.1 IS6110 transposase 2376628 5211993 MRA_2121 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283444.1 2375744 D 419947 CDS YP_001283445.1 148661922 5211994 2377261..2377557 1 NC_009525.1 PE family protein 2377557 5211994 MRA_2122 Mycobacterium tuberculosis H37Ra PE family protein YP_001283445.1 2377261 D 419947 CDS YP_001283446.1 148661923 5211995 2377613..2378344 1 NC_009525.1 PPE family protein 2378344 5211995 MRA_2123 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283446.1 2377613 D 419947 CDS YP_001283447.1 148661924 5211996 complement(2378885..2379631) 1 NC_009525.1 proteasome subunit alpha 2379631 prcA 5211996 prcA Mycobacterium tuberculosis H37Ra proteasome subunit alpha YP_001283447.1 2378885 R 419947 CDS YP_001283448.1 148661925 5211997 complement(2379628..2380503) 1 NC_009525.1 proteasome subunit beta 2380503 prcB 5211997 prcB Mycobacterium tuberculosis H37Ra proteasome subunit beta YP_001283448.1 2379628 R 419947 CDS YP_001283449.1 148661926 5211998 complement(2380500..2380694) 1 NC_009525.1 hypothetical protein 2380694 5211998 MRA_2126 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283449.1 2380500 R 419947 CDS YP_001283450.1 148661927 5211999 complement(2380807..2382471) 1 NC_009525.1 hypothetical protein 2382471 5211999 MRA_2127 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283450.1 2380807 R 419947 CDS YP_001283451.1 148661928 5212000 2382532..2383725 1 NC_009525.1 integral membrane protein 2383725 5212000 MRA_2128 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283451.1 2382532 D 419947 CDS YP_001283452.1 148661929 5213133 2383736..2384359 1 NC_009525.1 hypothetical protein 2384359 5213133 MRA_2129 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283452.1 2383736 D 419947 CDS YP_001283453.1 148661930 5213134 complement(2384363..2386192) 1 NC_009525.1 ATPase AAA 2386192 5213134 MRA_2130 Mycobacterium tuberculosis H37Ra ATPase AAA YP_001283453.1 2384363 R 419947 CDS YP_001283454.1 148661931 5213135 2386473..2387042 1 NC_009525.1 lipoprotein LppK 2387042 lppK 5213135 lppK Mycobacterium tuberculosis H37Ra lipoprotein LppK YP_001283454.1 2386473 D 419947 CDS YP_001283455.1 148661932 5213136 2387050..2387343 1 NC_009525.1 hypothetical protein 2387343 5213136 MRA_2132 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283455.1 2387050 D 419947 CDS YP_001283456.1 148661933 5213137 complement(2387372..2388214) 1 NC_009525.1 RNA methyltransferase 2388214 5213137 MRA_2133 Mycobacterium tuberculosis H37Ra RNA methyltransferase YP_001283456.1 2387372 R 419947 CDS YP_001283457.1 148661934 5213138 2388288..2389124 1 NC_009525.1 hypothetical protein 2389124 5213138 MRA_2134 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283457.1 2388288 D 419947 CDS YP_001283458.1 148661935 5213139 complement(2389147..2389629) 1 NC_009525.1 integral membrane protein 2389629 5213139 MRA_2135 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283458.1 2389147 R 419947 CDS YP_001283459.1 148661936 5213140 complement(2389708..2390562) 1 NC_009525.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2390562 hisG 5213140 hisG Mycobacterium tuberculosis H37Ra ATP phosphoribosyltransferase YP_001283459.1 2389708 R 419947 CDS YP_001283460.1 148661937 5212225 complement(2390565..2390846) 1 NC_009525.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2390846 hisE 5212225 hisE Mycobacterium tuberculosis H37Ra phosphoribosyl-ATP pyrophosphatase YP_001283460.1 2390565 R 419947 CDS YP_001283461.1 148661938 5212226 2390973..2392394 1 NC_009525.1 PPE family protein 2392394 5212226 MRA_2138 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283461.1 2390973 D 419947 CDS YP_001283462.1 148661939 5212227 complement(2392391..2395969) 1 NC_009525.1 methionine synthase, vitamin-b12 dependent isozyme; hypothetical protein 2395969 metH 5212227 metH Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283462.1 2392391 R 419947 CDS YP_001283463.1 148661940 5212228 2396195..2397073 1 NC_009525.1 hypothetical protein 2397073 5212228 MRA_2140 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283463.1 2396195 D 419947 CDS YP_001283464.1 148661941 5212229 complement(2397104..2397874) 1 NC_009525.1 PE-PGRS family protein 2397874 5212229 MRA_2140A Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283464.1 2397104 R 419947 CDS YP_001283465.1 148661942 5212230 2398518..2399987 1 NC_009525.1 L-asparagine permease AnsP1 2399987 ansP1 5212230 ansP1 Mycobacterium tuberculosis H37Ra L-asparagine permease AnsP1 YP_001283465.1 2398518 D 419947 CDS YP_001283466.1 148661943 5212231 2399987..2400190 1 NC_009525.1 transmembrane protein 2400190 5212231 MRA_2142 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283466.1 2399987 D 419947 CDS YP_001283467.1 148661944 5212232 complement(2400210..2401091) 1 NC_009525.1 short chain dehydrogenase 2401091 5212232 MRA_2143 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001283467.1 2400210 R 419947 CDS YP_001283468.1 148661945 5212969 complement(2401117..2402361) 1 NC_009525.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2402361 cysS1 5212969 cysS1 Mycobacterium tuberculosis H37Ra cysteinyl-tRNA synthetase YP_001283468.1 2401117 R 419947 CDS YP_001283469.1 148661946 5212970 complement(2402419..2403222) 1 NC_009525.1 monophosphatase CysQ 2403222 cysQ 5212970 cysQ Mycobacterium tuberculosis H37Ra monophosphatase CysQ YP_001283469.1 2402419 R 419947 CDS YP_001283470.1 148661947 5212971 2403313..2403543 1 NC_009525.1 hypothetical protein 2403543 5212971 MRA_2146 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283470.1 2403313 D 419947 CDS YP_001283471.1 148661948 5212972 complement(2403753..2404541) 1 NC_009525.1 hypothetical protein 2404541 5212972 MRA_2147 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283471.1 2403753 R 419947 CDS YP_001283472.1 148661949 5212973 complement(2404552..2405139) 1 NC_009525.1 hypothetical protein 2405139 5212973 MRA_2148 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283472.1 2404552 R 419947 CDS YP_001283473.1 148661950 5212974 complement(2405203..2405913) 1 NC_009525.1 hypothetical protein 2405913 5212974 MRA_2149 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283473.1 2405203 R 419947 CDS YP_001283474.1 148661951 5212975 complement(2405910..2406740) 1 NC_009525.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 2406740 uppP 5212975 uppP Mycobacterium tuberculosis H37Ra undecaprenyl pyrophosphate phosphatase YP_001283474.1 2405910 R 419947 CDS YP_001283475.1 148661952 5212976 complement(2406804..2407217) 1 NC_009525.1 hypothetical protein 2407217 5212976 MRA_2151 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283475.1 2406804 R 419947 CDS YP_001283476.1 148661953 5214723 2407232..2408308 1 NC_009525.1 lipoprotein LppL 2408308 lppL 5214723 lppL Mycobacterium tuberculosis H37Ra lipoprotein LppL YP_001283476.1 2407232 D 419947 CDS YP_001283477.1 148661954 5214724 2408622..2409695 1 NC_009525.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2409695 pyrD 5214724 pyrD Mycobacterium tuberculosis H37Ra dihydroorotate dehydrogenase 2 YP_001283477.1 2408622 D 419947 CDS YP_001283478.1 148661955 5214725 complement(2409700..2410230) 1 NC_009525.1 hypothetical protein 2410230 5214725 MRA_2154 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283478.1 2409700 R 419947 CDS YP_001283479.1 148661956 5214726 complement(2410278..2411624) 1 NC_009525.1 hypothetical protein 2411624 5214726 MRA_2155 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283479.1 2410278 R 419947 CDS YP_001283480.1 148661957 5214728 complement(2412095..2412412) 1 NC_009525.1 hypothetical protein 2412412 5214728 MRA_2156 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283480.1 2412095 R 419947 CDS YP_001283481.1 148661958 5214729 complement(2412409..2412624) 1 NC_009525.1 hypothetical protein 2412624 5214729 MRA_2157 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283481.1 2412409 R 419947 CDS YP_001283482.1 148661959 5215406 2412879..2413937 1 NC_009525.1 hypothetical protein 2413937 5215406 MRA_2158 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283482.1 2412879 D 419947 CDS YP_001283483.1 148661960 5215407 complement(2414067..2414423) 1 NC_009525.1 transmembrane protein 2414423 5215407 MRA_2159 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283483.1 2414067 R 419947 CDS YP_001283484.1 148661961 5215408 complement(2414518..2415300) 1 NC_009525.1 hypothetical protein 2415300 wag31 5215408 wag31 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283484.1 2414518 R 419947 CDS YP_001283485.1 148661962 5215409 complement(2415568..2415858) 1 NC_009525.1 transmembrane protein 2415858 5215409 MRA_2161 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283485.1 2415568 R 419947 CDS YP_001283486.1 148661963 5215410 complement(2416020..2416745) 1 NC_009525.1 hypothetical protein 2416745 5215410 MRA_2162 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283486.1 2416020 R 419947 CDS YP_001283487.1 148661964 5215411 complement(2416742..2417518) 1 NC_009525.1 hypothetical protein 2417518 5215411 MRA_2163 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283487.1 2416742 R 419947 CDS YP_001283488.1 148661965 5215412 complement(2417524..2418276) 1 NC_009525.1 hypothetical protein 2418276 yfiH 5215412 yfiH Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283488.1 2417524 R 419947 CDS YP_001283489.1 148661966 5215413 complement(2418287..2419426) 1 NC_009525.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2419426 ftsZ 5215413 ftsZ Mycobacterium tuberculosis H37Ra cell division protein FtsZ YP_001283489.1 2418287 R 419947 CDS YP_001283490.1 148661967 5215649 complement(2419599..2420543) 1 NC_009525.1 cell division protein FtsQ 2420543 ftsQ 5215649 ftsQ Mycobacterium tuberculosis H37Ra cell division protein FtsQ YP_001283490.1 2419599 R 419947 CDS YP_001283491.1 148661968 5215650 complement(2420540..2422024) 1 NC_009525.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2422024 murC 5215650 murC Mycobacterium tuberculosis H37Ra UDP-N-acetylmuramate--L-alanine ligase YP_001283491.1 2420540 R 419947 CDS YP_001283492.1 148661969 5215651 complement(2422021..2423253) 1 NC_009525.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 2423253 murG 5215651 murG Mycobacterium tuberculosis H37Ra undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001283492.1 2422021 R 419947 CDS YP_001283493.1 148661970 5215652 complement(2423250..2424824) 1 NC_009525.1 cell division protein FtsW 2424824 ftsW 5215652 ftsW Mycobacterium tuberculosis H37Ra cell division protein FtsW YP_001283493.1 2423250 R 419947 CDS YP_001283494.1 148661971 5215653 complement(2424836..2426296) 1 NC_009525.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 2426296 murD 5215653 murD Mycobacterium tuberculosis H37Ra UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001283494.1 2424836 R 419947 CDS YP_001283495.1 148661972 5215654 complement(2426298..2427377) 1 NC_009525.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2427377 mraY 5215654 mraY Mycobacterium tuberculosis H37Ra phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001283495.1 2426298 R 419947 CDS YP_001283496.1 148661973 5215655 complement(2427374..2428906) 1 NC_009525.1 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 2428906 murF 5215655 murF Mycobacterium tuberculosis H37Ra UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF YP_001283496.1 2427374 R 419947 CDS YP_001283497.1 148661974 5215656 complement(2428903..2430510) 1 NC_009525.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 2430510 murE 5215656 murE Mycobacterium tuberculosis H37Ra UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001283497.1 2428903 R 419947 CDS YP_001283498.1 148661975 5212948 complement(2430533..2431567) 1 NC_009525.1 hypothetical protein 2431567 5212948 MRA_2174 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283498.1 2430533 R 419947 CDS YP_001283499.1 148661976 5212949 complement(2431564..2431905) 1 NC_009525.1 hypothetical protein 2431905 5212949 MRA_2175 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283499.1 2431564 R 419947 CDS YP_001283500.1 148661977 5212950 complement(2432173..2433039) 1 NC_009525.1 hypothetical protein 2433039 5212950 MRA_2176 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283500.1 2432173 R 419947 CDS YP_001283501.1 148661978 5212951 complement(2433142..2434740) 1 NC_009525.1 PE-PGRS family protein 2434740 5212951 MRA_2177 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283501.1 2433142 R 419947 CDS YP_001283502.1 148661979 5212952 complement(2434950..2436989) 1 NC_009525.1 penicillin-binding membrane protein PbpB 2436989 pbpB 5212952 pbpB Mycobacterium tuberculosis H37Ra penicillin-binding membrane protein PbpB YP_001283502.1 2434950 R 419947 CDS YP_001283503.1 148661980 5212953 complement(2436986..2438140) 1 NC_009525.1 hypothetical protein 2438140 5212953 MRA_2179 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283503.1 2436986 R 419947 CDS YP_001283504.1 148661981 5212954 complement(2438137..2439327) 1 NC_009525.1 S-adenosyl-methyltransferase MraW 2439327 mraW 5212954 mraW Mycobacterium tuberculosis H37Ra S-adenosyl-methyltransferase MraW YP_001283504.1 2438137 R 419947 CDS YP_001283505.1 148661982 5212955 complement(2439329..2439760) 1 NC_009525.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 2439760 5212955 MRA_2181 Mycobacterium tuberculosis H37Ra cell division protein MraZ YP_001283505.1 2439329 R 419947 CDS YP_001283506.1 148661983 5211687 complement(2440061..2440945) 1 NC_009525.1 IS6110 transposase 2440945 5211687 MRA_2182 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283506.1 2440061 R 419947 CDS YP_001283507.1 148661984 5211688 complement(2440996..2441322) 1 NC_009525.1 IS6110 hypothetical protein 2441322 5211688 MRA_2183 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283507.1 2440996 R 419947 CDS YP_001283508.1 148661985 5211689 complement(2441467..2441871) 1 NC_009525.1 transmembrane protein 2441871 5211689 MRA_2184 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283508.1 2441467 R 419947 CDS YP_001283509.1 148661986 5211690 2442137..2442757 1 NC_009525.1 hypothetical protein 2442757 5211690 MRA_2185 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283509.1 2442137 D 419947 CDS YP_001283510.1 148661987 5211691 2442853..2443536 1 NC_009525.1 lipoprotein LppM 2443536 lppM 5211691 lppM Mycobacterium tuberculosis H37Ra lipoprotein LppM YP_001283510.1 2442853 D 419947 CDS YP_001283511.1 148661988 5211692 complement(2443533..2444438) 1 NC_009525.1 hypothetical protein 2444438 5211692 MRA_2187 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283511.1 2443533 R 419947 CDS YP_001283512.1 148661989 5211693 2444749..2445807 1 NC_009525.1 geranylgeranyl pyrophosphate synthetase IdsA2 2445807 idsA2 5211693 idsA2 Mycobacterium tuberculosis H37Ra geranylgeranyl pyrophosphate synthetase IdsA2 YP_001283512.1 2444749 D 419947 CDS YP_001283513.1 148661990 5211694 2445811..2447361 1 NC_009525.1 integral membrane protein 2447361 5211694 MRA_2189 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283513.1 2445811 D 419947 CDS YP_001283514.1 148661991 5212845 complement(2447348..2447788) 1 NC_009525.1 hypothetical protein 2447788 5212845 MRA_2190 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283514.1 2447348 R 419947 CDS YP_001283515.1 148661992 5212846 2447843..2449042 1 NC_009525.1 serine/threonine protein kinase 2449042 pknL 5212846 pknL Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001283515.1 2447843 D 419947 CDS YP_001283516.1 148661993 5212847 complement(2449184..2449849) 1 NC_009525.1 transposase 2449849 5212847 MRA_2192 Mycobacterium tuberculosis H37Ra transposase YP_001283516.1 2449184 R 419947 CDS YP_001283517.1 148661994 5212848 complement(2450234..2451622) 1 NC_009525.1 phospho-2-dehydro-3-deoxyheptonate aldolase 2451622 aroG 5212848 aroG Mycobacterium tuberculosis H37Ra phospho-2-dehydro-3-deoxyheptonate aldolase YP_001283517.1 2450234 R 419947 CDS YP_001283518.1 148661995 5212849 complement(2451713..2452219) 1 NC_009525.1 hypothetical protein 2452219 5212849 MRA_2194 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283518.1 2451713 R 419947 CDS YP_001283519.1 148661996 5212850 complement(2452229..2453116) 1 NC_009525.1 integral membrane protein 2453116 5212850 MRA_2195 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283519.1 2452229 R 419947 CDS YP_001283520.1 148661997 5212851 2453204..2454487 1 NC_009525.1 integral membrane protein 2454487 5212851 MRA_2196 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283520.1 2453204 D 419947 CDS YP_001283521.1 148661998 5212852 complement(2454488..2455231) 1 NC_009525.1 1-acylglycerol-3-phosphate O-acyltransferase 2455231 5212852 MRA_2197 Mycobacterium tuberculosis H37Ra 1-acylglycerol-3-phosphate O-acyltransferase YP_001283521.1 2454488 R 419947 CDS YP_001283522.1 148661999 5214558 complement(2455317..2455712) 1 NC_009525.1 hypothetical protein 2455712 5214558 MRA_2198 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283522.1 2455317 R 419947 CDS YP_001283523.1 148662000 5214559 complement(2455709..2456848) 1 NC_009525.1 hypothetical protein 2456848 5214559 MRA_2199 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283523.1 2455709 R 419947 CDS YP_001283524.1 148662001 5214560 complement(2456968..2457402) 1 NC_009525.1 hypothetical protein 2457402 5214560 MRA_2200 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283524.1 2456968 R 419947 CDS YP_001283525.1 148662002 5214561 complement(2457507..2457896) 1 NC_009525.1 hypothetical protein 2457896 5214561 MRA_2201 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283525.1 2457507 R 419947 CDS YP_001283526.1 148662003 5214562 2458062..2459864 1 NC_009525.1 long-chain-fatty-acid--CoA ligase 2459864 fadD15 5214562 fadD15 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--CoA ligase YP_001283526.1 2458062 D 419947 CDS YP_001283527.1 148662004 5214563 complement(2459895..2461052) 1 NC_009525.1 glycosyl transferase 2461052 5214563 MRA_2203 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001283527.1 2459895 R 419947 CDS YP_001283528.1 148662005 5214564 complement(2461149..2461922) 1 NC_009525.1 hypothetical protein 2461922 5214564 MRA_2204 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283528.1 2461149 R 419947 CDS YP_001283529.1 148662006 5214565 complement(2462017..2463174) 1 NC_009525.1 hypothetical protein 2463174 5214565 MRA_2205 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283529.1 2462017 R 419947 CDS YP_001283530.1 148662007 5212694 complement(2463360..2463611) 1 NC_009525.1 hypothetical protein 2463611 5212694 MRA_2206 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283530.1 2463360 R 419947 CDS YP_001283531.1 148662008 5212695 2463721..2465658 1 NC_009525.1 contains 3'-5'exonuclease domain; hypothetical protein 2465658 5212695 MRA_2207 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283531.1 2463721 D 419947 CDS YP_001283532.1 148662009 5212696 complement(2465533..2466645) 1 NC_009525.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 2466645 trpD 5212696 trpD Mycobacterium tuberculosis H37Ra anthranilate phosphoribosyltransferase YP_001283532.1 2465533 R 419947 CDS YP_001283533.1 148662010 5212697 2466803..2467414 1 NC_009525.1 cytochrome c oxidase subunit III 2467414 ctaE 5212697 ctaE Mycobacterium tuberculosis H37Ra cytochrome c oxidase subunit III YP_001283533.1 2466803 D 419947 CDS YP_001283534.1 148662011 5212698 2467455..2468297 1 NC_009525.1 cytochrome c family protein 2468297 qcrC 5212698 qcrC Mycobacterium tuberculosis H37Ra cytochrome c family protein YP_001283534.1 2467455 D 419947 CDS YP_001283535.1 148662012 5212699 2468294..2469583 1 NC_009525.1 iron-sulfur protein 2469583 qcrA 5212699 qcrA Mycobacterium tuberculosis H37Ra iron-sulfur protein YP_001283535.1 2468294 D 419947 CDS YP_001283536.1 148662013 5212700 2469580..2471229 1 NC_009525.1 ubiquinol-cytochrome C reductase QcrB 2471229 qcrB 5212700 qcrB Mycobacterium tuberculosis H37Ra ubiquinol-cytochrome C reductase QcrB YP_001283536.1 2469580 D 419947 CDS YP_001283537.1 148662014 5212701 complement(2471406..2472050) 1 NC_009525.1 transmembrane protein 2472050 5212701 MRA_2213 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283537.1 2471406 R 419947 CDS YP_001283538.1 148662015 5214746 complement(2472050..2472949) 1 NC_009525.1 membrane protein MmpS3 2472949 mmpS3 5214746 mmpS3 Mycobacterium tuberculosis H37Ra membrane protein MmpS3 YP_001283538.1 2472050 R 419947 CDS YP_001283539.1 148662016 5214747 complement(2473135..2473554) 1 NC_009525.1 integral membrane protein 2473554 5214747 MRA_2215 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283539.1 2473135 R 419947 CDS YP_001283540.1 148662017 5214748 complement(2473562..2474653) 1 NC_009525.1 cytochrome c oxidase subunit II 2474653 ctaC 5214748 ctaC Mycobacterium tuberculosis H37Ra cytochrome c oxidase subunit II YP_001283540.1 2473562 R 419947 CDS YP_001283541.1 148662018 5214749 2474899..2476857 1 NC_009525.1 asparagine synthetase 2476857 asnB 5214749 asnB Mycobacterium tuberculosis H37Ra asparagine synthetase YP_001283541.1 2474899 D 419947 CDS YP_001283542.1 148662019 5214750 complement(2476955..2477929) 1 NC_009525.1 carbohydrate kinase CbhK 2477929 cbhK 5214750 cbhK Mycobacterium tuberculosis H37Ra carbohydrate kinase CbhK YP_001283542.1 2476955 R 419947 CDS YP_001283543.1 148662020 5214751 2478133..2478825 1 NC_009525.1 hypothetical protein 2478825 5214751 MRA_2219 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283543.1 2478133 D 419947 CDS YP_001283544.1 148662021 5214752 complement(2478833..2479189) 1 NC_009525.1 hypothetical protein 2479189 5214752 MRA_2220 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283544.1 2478833 R 419947 CDS YP_001283545.1 148662022 5214753 complement(2479289..2480575) 1 NC_009525.1 hypothetical protein 2480575 5214753 MRA_2221 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283545.1 2479289 R 419947 CDS YP_001283546.1 148662023 5214893 2480524..2481234 1 NC_009525.1 transmembrane protein 2481234 5214893 MRA_2222 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283546.1 2480524 D 419947 CDS YP_001283547.1 148662024 5214894 2481313..2482398 1 NC_009525.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2482398 cobT 5214894 cobT Mycobacterium tuberculosis H37Ra nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_001283547.1 2481313 D 419947 CDS YP_001283548.1 148662025 5214895 2482395..2483144 1 NC_009525.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2483144 cobS 5214895 cobS Mycobacterium tuberculosis H37Ra cobalamin synthase YP_001283548.1 2482395 D 419947 CDS YP_001283549.1 148662026 5214896 2483302..2484840 1 NC_009525.1 integral membrane protein 2484840 5214896 MRA_2225 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283549.1 2483302 D 419947 CDS YP_001283550.1 148662027 5214897 complement(2484766..2485872) 1 NC_009525.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 2485872 ilvE 5214897 ilvE Mycobacterium tuberculosis H37Ra branched-chain amino acid aminotransferase YP_001283550.1 2484766 R 419947 CDS YP_001283551.1 148662028 5214898 complement(2485944..2487083) 1 NC_009525.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 2487083 gcvT 5214898 gcvT Mycobacterium tuberculosis H37Ra glycine cleavage system aminomethyltransferase T YP_001283551.1 2485944 R 419947 CDS YP_001283552.1 148662029 5214899 2487092..2488228 1 NC_009525.1 hypothetical protein 2488228 5214899 MRA_2228 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283552.1 2487092 D 419947 CDS YP_001283553.1 148662030 5214900 2488240..2489787 1 NC_009525.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 2489787 pepB 5214900 pepB Mycobacterium tuberculosis H37Ra leucyl aminopeptidase YP_001283553.1 2488240 D 419947 CDS YP_001283554.1 148662031 5214960 complement(2489825..2491603) 1 NC_009525.1 short chain dehydrogenase 2491603 ephD 5214960 ephD Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001283554.1 2489825 R 419947 CDS YP_001283555.1 148662032 5214961 2491867..2493528 1 NC_009525.1 E2 component of pyruvate; dihydrolipoamide acetyltransferase 2493528 dlaT 5214961 dlaT Mycobacterium tuberculosis H37Ra dihydrolipoamide acetyltransferase YP_001283555.1 2491867 D 419947 CDS YP_001283556.1 148662033 5214962 2493528..2494433 1 NC_009525.1 hypothetical protein 2494433 5214962 MRA_2232 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283556.1 2493528 D 419947 CDS YP_001283557.1 148662034 5214963 2494486..2495178 1 NC_009525.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 2495178 lipB 5214963 lipB Mycobacterium tuberculosis H37Ra lipoate-protein ligase B YP_001283557.1 2494486 D 419947 CDS YP_001283558.1 148662035 5214964 2495175..2496110 1 NC_009525.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2496110 lipA 5214964 lipA Mycobacterium tuberculosis H37Ra lipoyl synthase YP_001283558.1 2495175 D 419947 CDS YP_001283559.1 148662036 5214965 2496137..2496889 1 NC_009525.1 transmembrane protein 2496889 5214965 MRA_2235 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283559.1 2496137 D 419947 CDS YP_001283560.1 148662037 5214966 complement(2496896..2497318) 1 NC_009525.1 hypothetical protein 2497318 5214966 MRA_2236 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283560.1 2496896 R 419947 CDS YP_001283561.1 148662038 5214967 2497517..2498953 1 NC_009525.1 glutamine synthetase 2498953 glnA1 5214967 glnA1 Mycobacterium tuberculosis H37Ra glutamine synthetase YP_001283561.1 2497517 D 419947 CDS YP_001283562.1 148662039 5215467 complement(2499271..2502255) 1 NC_009525.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 2502255 glnE 5215467 glnE Mycobacterium tuberculosis H37Ra bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_001283562.1 2499271 R 419947 CDS YP_001283563.1 148662040 5215468 complement(2502304..2503644) 1 NC_009525.1 glutamine synthetase 2503644 glnA2 5215468 glnA2 Mycobacterium tuberculosis H37Ra glutamine synthetase YP_001283563.1 2502304 R 419947 CDS YP_001283564.1 148662041 5215469 complement(2503739..2505301) 1 NC_009525.1 proteinase 2505301 5215469 MRA_2240 Mycobacterium tuberculosis H37Ra proteinase YP_001283564.1 2503739 R 419947 CDS YP_001283565.1 148662042 5215470 complement(2505363..2506925) 1 NC_009525.1 exported protease 2506925 5215470 MRA_2241 Mycobacterium tuberculosis H37Ra exported protease YP_001283565.1 2505363 R 419947 CDS YP_001283566.1 148662043 5215471 complement(2507127..2507348) 1 NC_009525.1 hypothetical protein 2507348 5215471 MRA_2242 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283566.1 2507127 R 419947 CDS YP_001283567.1 148662044 5215472 2507644..2508489 1 NC_009525.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 2508489 panB 5215472 panB Mycobacterium tuberculosis H37Ra 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001283567.1 2507644 D 419947 CDS YP_001283568.1 148662045 5215473 2508734..2510275 1 NC_009525.1 hypothetical protein 2510275 5215473 MRA_2244 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283568.1 2508734 D 419947 CDS YP_001283569.1 148662046 5214662 2510768..2511052 1 NC_009525.1 hypothetical protein 2511052 5214662 MRA_2245 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283569.1 2510768 D 419947 CDS YP_001283570.1 148662047 5214663 complement(2511238..2511540) 1 NC_009525.1 hypothetical protein 2511540 5214663 MRA_2246 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283570.1 2511238 R 419947 CDS YP_001283571.1 148662048 5214664 complement(2511546..2512640) 1 NC_009525.1 bifunctional RNase H/acid phosphatase 2512640 5214664 MRA_2247 Mycobacterium tuberculosis H37Ra bifunctional RNase H/acid phosphatase YP_001283571.1 2511546 R 419947 CDS YP_001283572.1 148662049 5214665 complement(2512637..2513374) 1 NC_009525.1 hypothetical protein 2513374 5214665 MRA_2248 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283572.1 2512637 R 419947 CDS YP_001283573.1 148662050 5214666 complement(2513371..2514510) 1 NC_009525.1 hypothetical protein 2514510 5214666 MRA_2249 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283573.1 2513371 R 419947 CDS YP_001283574.1 148662051 5214667 complement(2514507..2515601) 1 NC_009525.1 hypothetical protein 2515601 cobC 5214667 cobC Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283574.1 2514507 R 419947 CDS YP_001283575.1 148662052 5214668 complement(2515616..2515987) 1 NC_009525.1 hypothetical protein 2515987 5214668 MRA_2251 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283575.1 2515616 R 419947 CDS YP_001283576.1 148662053 5213366 2516180..2517055 1 NC_009525.1 hypothetical protein 2517055 5213366 MRA_2252 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283576.1 2516180 D 419947 CDS YP_001283577.1 148662054 5213367 2517048..2517539 1 NC_009525.1 protein tyrosine phosphatase 2517539 ptpA 5213367 ptpA Mycobacterium tuberculosis H37Ra protein tyrosine phosphatase YP_001283577.1 2517048 D 419947 CDS YP_001283578.1 148662055 5213368 2517539..2518354 1 NC_009525.1 surfeit locus protein 1 2518354 surF1 5213368 surF1 Mycobacterium tuberculosis H37Ra surfeit locus protein 1 YP_001283578.1 2517539 D 419947 CDS YP_001283579.1 148662056 5213369 complement(2518336..2519277) 1 NC_009525.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 2519277 cobD 5213369 cobD Mycobacterium tuberculosis H37Ra cobalamin biosynthesis protein YP_001283579.1 2518336 R 419947 CDS YP_001283580.1 148662057 5213370 2519391..2520158 1 NC_009525.1 hypothetical protein 2520158 5213370 MRA_2256 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283580.1 2519391 D 419947 CDS YP_001283581.1 148662058 5213371 complement(2520253..2520489) 1 NC_009525.1 hypothetical protein 2520489 5213371 MRA_2257 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283581.1 2520253 R 419947 CDS YP_001283582.1 148662059 5213373 complement(2520617..2521078) 1 NC_009525.1 AhpC/TSA family protein 2521078 ahpE 5213373 ahpE Mycobacterium tuberculosis H37Ra AhpC/TSA family protein YP_001283582.1 2520617 R 419947 CDS YP_001283583.1 148662060 5213383 complement(2521078..2521554) 1 NC_009525.1 hypothetical protein 2521554 5213383 MRA_2259 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283583.1 2521078 R 419947 CDS YP_001283584.1 148662061 5213384 complement(2521592..2522389) 1 NC_009525.1 hypothetical protein 2522389 5213384 MRA_2260 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283584.1 2521592 R 419947 CDS YP_001283585.1 148662062 5213385 2522441..2525146 1 NC_009525.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 2525146 aceE 5213385 aceE Mycobacterium tuberculosis H37Ra pyruvate dehydrogenase subunit E1 YP_001283585.1 2522441 D 419947 CDS YP_001283586.1 148662063 5213386 2525206..2526450 1 NC_009525.1 hypothetical protein 2526450 5213386 MRA_2262 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283586.1 2525206 D 419947 CDS YP_001283587.1 148662064 5213387 2526689..2527597 1 NC_009525.1 malonyl CoA acyl carrier protein transacylase FabD 2527597 fabD 5213387 fabD Mycobacterium tuberculosis H37Ra malonyl CoA acyl carrier protein transacylase FabD YP_001283587.1 2526689 D 419947 CDS YP_001283588.1 148662065 5213388 2527673..2528020 1 NC_009525.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 2528020 acpP 5213388 acpP Mycobacterium tuberculosis H37Ra acyl carrier protein YP_001283588.1 2527673 D 419947 CDS YP_001283589.1 148662066 5213389 2528017..2529267 1 NC_009525.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2529267 kasA 5213389 kasA Mycobacterium tuberculosis H37Ra 3-oxoacyl-ACP synthase YP_001283589.1 2528017 D 419947 CDS YP_001283590.1 148662067 5212822 2529298..2530614 1 NC_009525.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2530614 kasB 5212822 kasB Mycobacterium tuberculosis H37Ra 3-oxoacyl-ACP synthase YP_001283590.1 2529298 D 419947 CDS YP_001283591.1 148662068 5212823 2530645..2532066 1 NC_009525.1 propionyl-CoA carboxylase subunit beta 2532066 accD6 5212823 accD6 Mycobacterium tuberculosis H37Ra propionyl-CoA carboxylase subunit beta YP_001283591.1 2530645 D 419947 CDS YP_001283592.1 148662069 5212824 2532262..2533077 1 NC_009525.1 hypothetical protein 2533077 5212824 MRA_2268 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283592.1 2532262 D 419947 CDS YP_001283593.1 148662070 5212825 complement(2533146..2534696) 1 NC_009525.1 glycerol-3-phosphate dehydrogenase Glpd1 2534696 glpD1 5212825 glpD1 Mycobacterium tuberculosis H37Ra glycerol-3-phosphate dehydrogenase Glpd1 YP_001283593.1 2533146 R 419947 CDS YP_001283594.1 148662071 5212826 complement(2534690..2535259) 1 NC_009525.1 transcriptional regulatory protein 2535259 5212826 MRA_2270 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283594.1 2534690 R 419947 CDS YP_001283595.1 148662072 5212827 2535307..2536896 1 NC_009525.1 flavoprotein 2536896 5212827 MRA_2271 Mycobacterium tuberculosis H37Ra flavoprotein YP_001283595.1 2535307 D 419947 CDS YP_001283596.1 148662073 5212828 2536893..2537822 1 NC_009525.1 involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); the enzyme from Mycobacterium tuberculosis can phosphorylate a variety of amphipathic lipids; diacylglycerol kinase 2537822 5212828 MRA_2272 Mycobacterium tuberculosis H37Ra diacylglycerol kinase YP_001283596.1 2536893 D 419947 CDS YP_001283597.1 148662074 5212829 2537888..2538391 1 NC_009525.1 secreted protein 2538391 5212829 MRA_2273 Mycobacterium tuberculosis H37Ra secreted protein YP_001283597.1 2537888 D 419947 CDS YP_001283598.1 148662075 5213293 complement(2538424..2538879) 1 NC_009525.1 integral membrane protein 2538879 5213293 MRA_2274 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283598.1 2538424 R 419947 CDS YP_001283599.1 148662076 5213294 complement(2538884..2539078) 1 NC_009525.1 hypothetical protein 2539078 5213294 MRA_2275 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283599.1 2538884 R 419947 CDS YP_001283600.1 148662077 5213295 2538998..2539216 1 NC_009525.1 hypothetical protein 2539216 5213295 MRA_2276 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283600.1 2538998 D 419947 CDS YP_001283601.1 148662078 5213296 complement(2539245..2539778) 1 NC_009525.1 hypothetical protein 2539778 5213296 MRA_2277 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283601.1 2539245 R 419947 CDS YP_001283602.1 148662079 5213297 complement(2539908..2540726) 1 NC_009525.1 hypothetical protein 2540726 5213297 MRA_2278 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283602.1 2539908 R 419947 CDS YP_001283603.1 148662080 5213298 complement(2540740..2541801) 1 NC_009525.1 transcriptional regulatory protein 2541801 5213298 MRA_2279 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283603.1 2540740 R 419947 CDS YP_001283604.1 148662081 5213299 2542149..2543234 1 NC_009525.1 zinc-dependent alcohol dehydrogenase AdhE2 2543234 adhE2 5213299 adhE2 Mycobacterium tuberculosis H37Ra zinc-dependent alcohol dehydrogenase AdhE2 YP_001283604.1 2542149 D 419947 CDS YP_001283605.1 148662082 5213300 2543234..2543869 1 NC_009525.1 hypothetical protein 2543869 5213300 MRA_2281 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283605.1 2543234 D 419947 CDS YP_001283606.1 148662083 5215177 complement(2543946..2544368) 1 NC_009525.1 hypothetical protein 2544368 5215177 MRA_2281A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283606.1 2543946 R 419947 CDS YP_001283607.1 148662084 5215178 complement(2544374..2545456) 1 NC_009525.1 apolipoprotein N-acyltransferase 2545456 5215178 MRA_2282 Mycobacterium tuberculosis H37Ra apolipoprotein N-acyltransferase YP_001283607.1 2544374 R 419947 CDS YP_001283608.1 148662085 5215179 2545545..2546498 1 NC_009525.1 short chain dehydrogenase 2546498 5215179 MRA_2283 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001283608.1 2545545 D 419947 CDS YP_001283609.1 148662086 5215180 complement(2546476..2548254) 1 NC_009525.1 hypothetical protein 2548254 5215180 MRA_2284 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283609.1 2546476 R 419947 CDS YP_001283610.1 148662087 5215181 2548604..2549833 1 NC_009525.1 integral membrane protein 2549833 5215181 MRA_2285 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283610.1 2548604 D 419947 CDS YP_001283611.1 148662088 5215182 2550008..2551294 1 NC_009525.1 cytochrome p450 124 CYP124 2551294 cyp124 5215182 cyp124 Mycobacterium tuberculosis H37Ra cytochrome p450 124 CYP124 YP_001283611.1 2550008 D 419947 CDS YP_001283612.1 148662089 5215183 complement(2551548..2552714) 1 NC_009525.1 hypothetical protein 2552714 5215183 MRA_2287 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283612.1 2551548 R 419947 CDS YP_001283613.1 148662090 5215184 complement(2552711..2554180) 1 NC_009525.1 cytochrome p450 128 CYP128 2554180 cyp128 5215184 cyp128 Mycobacterium tuberculosis H37Ra cytochrome p450 128 CYP128 YP_001283613.1 2552711 R 419947 CDS YP_001283614.1 148662091 5215641 complement(2554193..2554525) 1 NC_009525.1 hypothetical protein 2554525 5215641 MRA_2288A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283614.1 2554193 R 419947 CDS YP_001283615.1 148662092 5215642 2554602..2555129 1 NC_009525.1 lipoprotein LppN 2555129 lppN 5215642 lppN Mycobacterium tuberculosis H37Ra lipoprotein LppN YP_001283615.1 2554602 D 419947 CDS YP_001283616.1 148662093 5215643 2555236..2555535 1 NC_009525.1 hypothetical protein 2555535 5215643 MRA_2290 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283616.1 2555236 D 419947 CDS YP_001283617.1 148662094 5215644 2555641..2556009 1 NC_009525.1 transmembrane protein 2556009 5215644 MRA_2291 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283617.1 2555641 D 419947 CDS YP_001283618.1 148662095 5215645 2556006..2556335 1 NC_009525.1 transmembrane protein 2556335 5215645 MRA_2292 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283618.1 2556006 D 419947 CDS YP_001283619.1 148662096 5215646 complement(2556392..2556709) 1 NC_009525.1 hypothetical protein 2556709 5215646 MRA_2293 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283619.1 2556392 R 419947 CDS YP_001283620.1 148662097 5215647 2556787..2557656 1 NC_009525.1 hypothetical protein 2557656 5215647 MRA_2294 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283620.1 2556787 D 419947 CDS YP_001283621.1 148662098 5215648 2557653..2558843 1 NC_009525.1 cytochrome p450 121 cyp121 2558843 cyp121 5215648 cyp121 Mycobacterium tuberculosis H37Ra cytochrome p450 121 cyp121 YP_001283621.1 2557653 D 419947 CDS YP_001283622.1 148662099 5215673 complement(2559028..2559933) 1 NC_009525.1 glycerolphosphodiesterase 2559933 5215673 MRA_2296 Mycobacterium tuberculosis H37Ra glycerolphosphodiesterase YP_001283622.1 2559028 R 419947 CDS YP_001283623.1 148662100 5215674 2559969..2560295 1 NC_009525.1 IS6110 hypothetical protein 2560295 5215674 MRA_2297 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283623.1 2559969 D 419947 CDS YP_001283624.1 148662101 5215675 2560346..2561230 1 NC_009525.1 IS6110 transposase 2561230 5215675 MRA_2298 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283624.1 2560346 D 419947 CDS YP_001283625.1 148662102 5215676 2561464..2562843 1 NC_009525.1 dehydrogenase 2562843 5215676 MRA_2299 Mycobacterium tuberculosis H37Ra dehydrogenase YP_001283625.1 2561464 D 419947 CDS YP_001283626.1 148662103 5215677 2563077..2564735 1 NC_009525.1 phosphate-transport permease PitB 2564735 pitB 5215677 pitB Mycobacterium tuberculosis H37Ra phosphate-transport permease PitB YP_001283626.1 2563077 D 419947 CDS YP_001283627.1 148662104 5215678 complement(2564842..2565780) 1 NC_009525.1 LysR family transcriptional regulator 2565780 5215678 MRA_2301 Mycobacterium tuberculosis H37Ra LysR family transcriptional regulator YP_001283627.1 2564842 R 419947 CDS YP_001283628.1 148662105 5215679 2565845..2566039 1 NC_009525.1 hypothetical protein 2566039 5215679 MRA_2301A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283628.1 2565845 D 419947 CDS YP_001283629.1 148662106 5215680 2566049..2567344 1 NC_009525.1 esterase 2567344 lipM 5215680 lipM Mycobacterium tuberculosis H37Ra esterase YP_001283629.1 2566049 D 419947 CDS YP_001283630.1 148662107 5213793 2567377..2568714 1 NC_009525.1 hypothetical protein 2568714 5213793 MRA_2303 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283630.1 2567377 D 419947 CDS YP_001283631.1 148662108 5213794 complement(2568781..2569473) 1 NC_009525.1 hypothetical protein 2569473 5213794 MRA_2304 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283631.1 2568781 R 419947 CDS YP_001283632.1 148662109 5213795 2569607..2571235 1 NC_009525.1 Na+/H+ exchanger 2571235 yjcE 5213795 yjcE Mycobacterium tuberculosis H37Ra Na+/H+ exchanger YP_001283632.1 2569607 D 419947 CDS YP_001283633.1 148662110 5213796 2571232..2571609 1 NC_009525.1 hypothetical protein 2571609 5213796 MRA_2305A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283633.1 2571232 D 419947 CDS YP_001283634.1 148662111 5213797 2571579..2572361 1 NC_009525.1 CDP-diacylglycerol pyrophosphatase 2572361 cdh 5213797 cdh Mycobacterium tuberculosis H37Ra CDP-diacylglycerol pyrophosphatase YP_001283634.1 2571579 D 419947 CDS YP_001283635.1 148662112 5213798 2572503..2573018 1 NC_009525.1 lipoprotein LppO 2573018 lppO 5213798 lppO Mycobacterium tuberculosis H37Ra lipoprotein LppO YP_001283635.1 2572503 D 419947 CDS YP_001283636.1 148662113 5213799 2573078..2573932 1 NC_009525.1 thiosulfate sulfurtransferase SseB 2573932 sseB 5213799 sseB Mycobacterium tuberculosis H37Ra thiosulfate sulfurtransferase SseB YP_001283636.1 2573078 D 419947 CDS YP_001283637.1 148662114 5213800 complement(2573933..2574157) 1 NC_009525.1 hypothetical protein 2574157 5213800 MRA_2309 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283637.1 2573933 R 419947 CDS YP_001283638.1 148662115 5212436 complement(2574196..2574936) 1 NC_009525.1 hypothetical protein 2574936 5212436 MRA_2310 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283638.1 2574196 R 419947 CDS YP_001283639.1 148662116 5212437 2575231..2576454 1 NC_009525.1 aminotransferase 2576454 5212437 MRA_2311 Mycobacterium tuberculosis H37Ra aminotransferase YP_001283639.1 2575231 D 419947 CDS YP_001283640.1 148662117 5212438 2576676..2577314 1 NC_009525.1 hypothetical protein 2577314 5212438 MRA_2312 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283640.1 2576676 D 419947 CDS YP_001283641.1 148662118 5212439 2577408..2578310 1 NC_009525.1 haloalkane dehalogenase 2578310 5212439 MRA_2313 Mycobacterium tuberculosis H37Ra haloalkane dehalogenase YP_001283641.1 2577408 D 419947 CDS YP_001283642.1 148662119 5212440 2578342..2578794 1 NC_009525.1 hypothetical protein 2578794 5212440 MRA_2314 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283642.1 2578342 D 419947 CDS YP_001283643.1 148662120 5212441 2578986..2579957 1 NC_009525.1 oxidoreductase 2579957 5212441 MRA_2315 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001283643.1 2578986 D 419947 CDS YP_001283644.1 148662121 5212442 complement(2579963..2581906) 1 NC_009525.1 molecular chaperone; heat shock protein 90 2581906 htpG 5212442 htpG Mycobacterium tuberculosis H37Ra heat shock protein 90 YP_001283644.1 2579963 R 419947 CDS YP_001283645.1 148662122 5212443 complement(2581980..2582912) 1 NC_009525.1 hypothetical protein 2582912 5212443 MRA_2317 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283645.1 2581980 R 419947 CDS YP_001283646.1 148662123 5213507 2582919..2583611 1 NC_009525.1 cutinase Cut2 2583611 cut2 5213507 cut2 Mycobacterium tuberculosis H37Ra cutinase Cut2 YP_001283646.1 2582919 D 419947 CDS YP_001283647.1 148662124 5213508 2583717..2583959 1 NC_009525.1 hypothetical protein 2583959 5213508 MRA_2318A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283647.1 2583717 D 419947 CDS YP_001283648.1 148662125 5213509 complement(2584000..2584923) 1 NC_009525.1 antibiotic-resistance protein 2584923 5213509 MRA_2319 Mycobacterium tuberculosis H37Ra antibiotic-resistance protein YP_001283648.1 2584000 R 419947 CDS YP_001283649.1 148662126 5213510 complement(2584920..2585129) 1 NC_009525.1 hypothetical protein 2585129 5213510 MRA_2320 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283649.1 2584920 R 419947 CDS YP_001283650.1 148662127 5213511 2585713..2587002 1 NC_009525.1 hypothetical protein 2587002 5213511 MRA_2321 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283650.1 2585713 D 419947 CDS YP_001283651.1 148662128 5213512 2587392..2587826 1 NC_009525.1 hypothetical protein 2587826 5213512 MRA_2322 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283651.1 2587392 D 419947 CDS YP_001283652.1 148662129 5213513 complement(2587755..2588600) 1 NC_009525.1 hypothetical protein 2588600 5213513 MRA_2323 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283652.1 2587755 R 419947 CDS YP_001283653.1 148662130 5213514 complement(2589132..2589323) 1 NC_009525.1 hypothetical protein 2589323 5213514 MRA_2324 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283653.1 2589132 R 419947 CDS YP_001283654.1 148662131 5214348 complement(2589408..2589839) 1 NC_009525.1 hypothetical protein 2589839 5214348 MRA_2325 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283654.1 2589408 R 419947 CDS YP_001283655.1 148662132 5214349 complement(2589942..2590181) 1 NC_009525.1 hypothetical protein 2590181 5214349 MRA_2326 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283655.1 2589942 R 419947 CDS YP_001283656.1 148662133 5214350 2590323..2591039 1 NC_009525.1 hypothetical protein 2591039 5214350 MRA_2327 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283656.1 2590323 D 419947 CDS YP_001283657.1 148662134 5214351 2591112..2591381 1 NC_009525.1 hypothetical protein 2591381 5214351 MRA_2328 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283657.1 2591112 D 419947 CDS YP_001283658.1 148662135 5214353 complement(2591747..2592202) 1 NC_009525.1 integrase 2592202 5214353 MRA_2329 Mycobacterium tuberculosis H37Ra integrase YP_001283658.1 2591747 R 419947 CDS YP_001283659.1 148662136 5214354 2592949..2593236 1 NC_009525.1 hypothetical protein 2593236 5214354 MRA_2329A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283659.1 2592949 D 419947 CDS YP_001283660.1 148662137 5212458 2593339..2593683 1 NC_009525.1 excisionase 2593683 5212458 MRA_2330 Mycobacterium tuberculosis H37Ra excisionase YP_001283660.1 2593339 D 419947 CDS YP_001283661.1 148662138 5212459 2593788..2594312 1 NC_009525.1 hypothetical protein 2594312 5212459 MRA_2331 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283661.1 2593788 D 419947 CDS YP_001283662.1 148662139 5212460 2594390..2594659 1 NC_009525.1 hypothetical protein 2594659 5212460 MRA_2332 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283662.1 2594390 D 419947 CDS YP_001283663.1 148662140 5212461 complement(2594956..2595810) 1 NC_009525.1 hypothetical protein 2595810 5212461 MRA_2333 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283663.1 2594956 R 419947 CDS YP_001283664.1 148662141 5212462 complement(2595821..2597194) 1 NC_009525.1 hypothetical protein 2597194 5212462 MRA_2334 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283664.1 2595821 R 419947 CDS YP_001283665.1 148662142 5212463 complement(2597191..2598708) 1 NC_009525.1 hypothetical protein 2598708 5212463 MRA_2335 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283665.1 2597191 R 419947 CDS YP_001283666.1 148662143 5212464 2598742..2599614 1 NC_009525.1 sugar ABC transporter permease UspA 2599614 uspA 5212464 uspA Mycobacterium tuberculosis H37Ra sugar ABC transporter permease UspA YP_001283666.1 2598742 D 419947 CDS YP_001283667.1 148662144 5212465 2599601..2600425 1 NC_009525.1 sugar ABC transporter permease UspB 2600425 uspB 5212465 uspB Mycobacterium tuberculosis H37Ra sugar ABC transporter permease UspB YP_001283667.1 2599601 D 419947 CDS YP_001283668.1 148662145 5214771 2600422..2601744 1 NC_009525.1 sugar ABC transporter substrate-binding protein UspC 2601744 uspC 5214771 uspC Mycobacterium tuberculosis H37Ra sugar ABC transporter substrate-binding protein UspC YP_001283668.1 2600422 D 419947 CDS YP_001283669.1 148662146 5214772 complement(2601752..2602630) 1 NC_009525.1 hypothetical protein 2602630 5214772 MRA_2339 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283669.1 2601752 R 419947 CDS YP_001283670.1 148662147 5214773 complement(2602627..2604057) 1 NC_009525.1 cationic amino acid transport integral membrane protein RocE 2604057 rocE 5214773 rocE Mycobacterium tuberculosis H37Ra cationic amino acid transport integral membrane protein RocE YP_001283670.1 2602627 R 419947 CDS YP_001283671.1 148662148 5214774 complement(2604058..2604603) 1 NC_009525.1 ornithine aminotransferase RocD2 2604603 rocD2 5214774 rocD2 Mycobacterium tuberculosis H37Ra ornithine aminotransferase RocD2 YP_001283671.1 2604058 R 419947 CDS YP_001283672.1 148662149 5214775 complement(2604603..2605268) 1 NC_009525.1 ornithine aminotransferase RocD1 2605268 rocD1 5214775 rocD1 Mycobacterium tuberculosis H37Ra ornithine aminotransferase RocD1 YP_001283672.1 2604603 R 419947 CDS YP_001283673.1 148662150 5214776 complement(2605265..2606173) 1 NC_009525.1 hypothetical protein 2606173 5214776 MRA_2343 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283673.1 2605265 R 419947 CDS YP_001283674.1 148662151 5214777 2606238..2606684 1 NC_009525.1 transcription regulator AsnC 2606684 5214777 MRA_2344 Mycobacterium tuberculosis H37Ra transcription regulator AsnC YP_001283674.1 2606238 D 419947 CDS YP_001283675.1 148662152 5214778 complement(2606913..2607761) 1 NC_009525.1 hypothetical protein 2607761 5214778 MRA_2345 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283675.1 2606913 R 419947 CDS YP_001283676.1 148662153 5214686 complement(2607758..2609851) 1 NC_009525.1 cobalt ABC transporter ATP-binding protein 2609851 5214686 MRA_2346 Mycobacterium tuberculosis H37Ra cobalt ABC transporter ATP-binding protein YP_001283676.1 2607758 R 419947 CDS YP_001283677.1 148662154 5214687 2609892..2610383 1 NC_009525.1 hypothetical protein 2610383 5214687 MRA_2347 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283677.1 2609892 D 419947 CDS YP_001283678.1 148662155 5214688 2610635..2611783 1 NC_009525.1 PE family protein 2611783 5214688 MRA_2348 Mycobacterium tuberculosis H37Ra PE family protein YP_001283678.1 2610635 D 419947 CDS YP_001283679.1 148662156 5214689 complement(2611818..2613365) 1 NC_009525.1 nitrite extrusion protein 1 NarK1 2613365 narK1 5214689 narK1 Mycobacterium tuberculosis H37Ra nitrite extrusion protein 1 NarK1 YP_001283679.1 2611818 R 419947 CDS YP_001283680.1 148662157 5214690 complement(2613599..2614126) 1 NC_009525.1 lipoprotein LppP 2614126 lppP 5214690 lppP Mycobacterium tuberculosis H37Ra lipoprotein LppP YP_001283680.1 2613599 R 419947 CDS YP_001283681.1 148662158 5214691 2614201..2614587 1 NC_009525.1 hypothetical protein 2614587 5214691 MRA_2351 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283681.1 2614201 D 419947 CDS YP_001283682.1 148662159 5214692 2614644..2614982 1 NC_009525.1 hypothetical protein 2614982 5214692 MRA_2351A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283682.1 2614644 D 419947 CDS YP_001283683.1 148662160 5214693 2615012..2616658 1 NC_009525.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 2616658 mez 5214693 mez Mycobacterium tuberculosis H37Ra malate dehydrogenase YP_001283683.1 2615012 D 419947 CDS YP_001283684.1 148662161 5215253 complement(2616612..2618225) 1 NC_009525.1 integral membrane transport protein 2618225 5215253 MRA_2353 Mycobacterium tuberculosis H37Ra integral membrane transport protein YP_001283684.1 2616612 R 419947 CDS YP_001283685.1 148662162 5215254 2618700..2619632 1 NC_009525.1 cysteine synthase 2619632 cysK1 5215254 cysK1 Mycobacterium tuberculosis H37Ra cysteine synthase YP_001283685.1 2618700 D 419947 CDS YP_001283686.1 148662163 5215255 2619636..2620325 1 NC_009525.1 serine acetyltransferase CysE 2620325 cysE 5215255 cysE Mycobacterium tuberculosis H37Ra serine acetyltransferase CysE YP_001283686.1 2619636 D 419947 CDS YP_001283687.1 148662164 5215256 2620741..2621709 1 NC_009525.1 hypothetical protein 2621709 5215256 MRA_2356 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283687.1 2620741 D 419947 CDS YP_001283688.1 148662165 5215257 complement(2621773..2622891) 1 NC_009525.1 hypothetical protein 2622891 5215257 MRA_2357 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283688.1 2621773 R 419947 CDS YP_001283689.1 148662166 5215258 complement(2623011..2623967) 1 NC_009525.1 hypothetical protein 2623967 moeW 5215258 moeW Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283689.1 2623011 R 419947 CDS YP_001283690.1 148662167 5215259 2624597..2627485 1 NC_009525.1 transmembrane transport protein MmpL9 2627485 mmpL9 5215259 mmpL9 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL9 YP_001283690.1 2624597 D 419947 CDS YP_001283691.1 148662168 5215260 complement(2627571..2628812) 1 NC_009525.1 PE-PGRS family protein 2628812 5215260 MRA_2360 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283691.1 2627571 R 419947 CDS YP_001283692.1 148662169 5213179 2629501..2629920 1 NC_009525.1 lipoprotein LppQ 2629920 lppQ 5213179 lppQ Mycobacterium tuberculosis H37Ra lipoprotein LppQ YP_001283692.1 2629501 D 419947 CDS YP_001283693.1 148662170 5213180 2630176..2630433 1 NC_009525.1 hypothetical protein 2630433 5213180 MRA_2362 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283693.1 2630176 D 419947 CDS YP_001283694.1 148662171 5213181 complement(2630437..2632356) 1 NC_009525.1 synthesizes RNA primers at the replication forks; DNA primase 2632356 dnaG 5213181 dnaG Mycobacterium tuberculosis H37Ra DNA primase YP_001283694.1 2630437 R 419947 CDS YP_001283695.1 148662172 5213182 complement(2632361..2633656) 1 NC_009525.1 dGTPase type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 2633656 dgt 5213182 dgt Mycobacterium tuberculosis H37Ra deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_001283695.1 2632361 R 419947 CDS YP_001283696.1 148662173 5213183 2633725..2635707 1 NC_009525.1 transmembrane protein 2635707 5213183 MRA_2365 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283696.1 2633725 D 419947 CDS YP_001283697.1 148662174 5213184 complement(2635792..2636076) 1 NC_009525.1 esat-6 like protein EsxO 2636076 esxO 5213184 esxO Mycobacterium tuberculosis H37Ra esat-6 like protein EsxO YP_001283697.1 2635792 R 419947 CDS YP_001283698.1 148662175 5212283 complement(2636127..2636423) 1 NC_009525.1 esat-6 like protein EsxP 2636423 esxP 5212283 esxP Mycobacterium tuberculosis H37Ra esat-6 like protein EsxP YP_001283698.1 2636127 R 419947 CDS YP_001283699.1 148662176 5212284 complement(2636558..2636884) 1 NC_009525.1 hypothetical protein 2636884 5212284 MRA_2368 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283699.1 2636558 R 419947 CDS YP_001283700.1 148662177 5212285 complement(2637076..2638602) 1 NC_009525.1 phospholipase C 3 PlcC 2638602 plcC 5212285 plcC Mycobacterium tuberculosis H37Ra phospholipase C 3 PlcC YP_001283700.1 2637076 R 419947 CDS YP_001283701.1 148662178 5212286 complement(2638685..2640223) 1 NC_009525.1 membrane-associated phospholipase C 2 2640223 plcB 5212286 plcB Mycobacterium tuberculosis H37Ra membrane-associated phospholipase C 2 YP_001283701.1 2638685 R 419947 CDS YP_001283702.1 148662179 5212287 complement(2640441..2641979) 1 NC_009525.1 membrane-associated phospholipase C 1 2641979 plcA 5212287 plcA Mycobacterium tuberculosis H37Ra membrane-associated phospholipase C 1 YP_001283702.1 2640441 R 419947 CDS YP_001283703.1 148662180 5212288 2642469..2642696 1 NC_009525.1 hypothetical protein 2642696 5212288 MRA_2372 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283703.1 2642469 D 419947 CDS YP_001283704.1 148662181 5212289 complement(2642827..2644002) 1 NC_009525.1 PPE family protein 2644002 5212289 MRA_2373 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283704.1 2642827 R 419947 CDS YP_001283705.1 148662182 5212290 complement(2644204..2644488) 1 NC_009525.1 esat-6 like protein 2644488 5212290 MRA_2374 Mycobacterium tuberculosis H37Ra esat-6 like protein YP_001283705.1 2644204 R 419947 CDS YP_001283706.1 148662183 5213425 complement(2644503..2644826) 1 NC_009525.1 esat-6 like protein 2644826 5213425 MRA_2375 Mycobacterium tuberculosis H37Ra esat-6 like protein YP_001283706.1 2644503 R 419947 CDS YP_001283707.1 148662184 5213426 complement(2644891..2646066) 1 NC_009525.1 PPE family protein 2646066 5213426 MRA_2376 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283707.1 2644891 R 419947 CDS YP_001283708.1 148662185 5213427 complement(2646496..2647560) 1 NC_009525.1 PPE family protein 2647560 5213427 MRA_2377 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283708.1 2646496 R 419947 CDS YP_001283709.1 148662186 5213428 2647596..2647922 1 NC_009525.1 IS6110 hypothetical protein 2647922 5213428 MRA_2378 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283709.1 2647596 D 419947 CDS YP_001283710.1 148662187 5213429 2647973..2648857 1 NC_009525.1 IS6110 transposase 2648857 5213429 MRA_2379 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283710.1 2647973 D 419947 CDS YP_001283711.1 148662188 5213430 complement(2649656..2651503) 1 NC_009525.1 PPE family protein 2651503 5213430 MRA_2380 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283711.1 2649656 R 419947 CDS YP_001283712.1 148662189 5213431 complement(2651641..2653032) 1 NC_009525.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 2653032 glyS 5213431 glyS Mycobacterium tuberculosis H37Ra glycyl-tRNA synthetase YP_001283712.1 2651641 R 419947 CDS YP_001283713.1 148662190 5213432 2653214..2653621 1 NC_009525.1 transcription regulator ArsR 2653621 5213432 MRA_2382 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001283713.1 2653214 D 419947 CDS YP_001283714.1 148662191 5212771 2653618..2654010 1 NC_009525.1 ferric uptake regulation protein FurB 2654010 furB 5212771 furB Mycobacterium tuberculosis H37Ra ferric uptake regulation protein FurB YP_001283714.1 2653618 D 419947 CDS YP_001283715.1 148662192 5212772 complement(2654118..2654546) 1 NC_009525.1 hypothetical protein 2654546 5212772 MRA_2384 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283715.1 2654118 R 419947 CDS YP_001283716.1 148662193 5212773 complement(2654546..2655436) 1 NC_009525.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 2655436 5212773 MRA_2385 Mycobacterium tuberculosis H37Ra undecaprenyl pyrophosphate synthase YP_001283716.1 2654546 R 419947 CDS YP_001283717.1 148662194 5212774 complement(2655429..2656226) 1 NC_009525.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2656226 recO 5212774 recO Mycobacterium tuberculosis H37Ra DNA repair protein RecO YP_001283717.1 2655429 R 419947 CDS YP_001283718.1 148662195 5212775 2656288..2657742 1 NC_009525.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 2657742 amiA2 5212775 amiA2 Mycobacterium tuberculosis H37Ra amidase YP_001283718.1 2656288 D 419947 CDS YP_001283719.1 148662196 5212776 complement(2657739..2658641) 1 NC_009525.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2658641 era 5212776 era Mycobacterium tuberculosis H37Ra GTP-binding protein Era YP_001283719.1 2657739 R 419947 CDS YP_001283720.1 148662197 5212777 complement(2658715..2659056) 1 NC_009525.1 hypothetical protein 2659056 5212777 MRA_2389 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283720.1 2658715 R 419947 CDS YP_001283721.1 148662198 5212778 complement(2659028..2660335) 1 NC_009525.1 transmembrane protein 2660335 5212778 MRA_2390 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283721.1 2659028 R 419947 CDS YP_001283722.1 148662199 5212578 complement(2660332..2660880) 1 NC_009525.1 metalloprotease 2660880 5212578 MRA_2391 Mycobacterium tuberculosis H37Ra metalloprotease YP_001283722.1 2660332 R 419947 CDS YP_001283723.1 148662200 5212579 complement(2660884..2661942) 1 NC_009525.1 PhoH-like protein PhoH1 2661942 phoH1 5212579 phoH1 Mycobacterium tuberculosis H37Ra PhoH-like protein PhoH1 YP_001283723.1 2660884 R 419947 CDS YP_001283724.1 148662201 5212580 complement(2661914..2662216) 1 NC_009525.1 hypothetical protein 2662216 5212580 MRA_2392A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283724.1 2661914 R 419947 CDS YP_001283725.1 148662202 5212581 complement(2662213..2663526) 1 NC_009525.1 hypothetical protein 2663526 5212581 MRA_2393 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283725.1 2662213 R 419947 CDS YP_001283726.1 148662203 5212582 2663619..2663906 1 NC_009525.1 PE-PGRS family protein 2663906 5212582 MRA_2394 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283726.1 2663619 D 419947 CDS YP_001283727.1 148662204 5212583 complement(2664005..2664793) 1 NC_009525.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2664793 5212583 MRA_2395 Mycobacterium tuberculosis H37Ra 16S ribosomal RNA methyltransferase RsmE YP_001283727.1 2664005 R 419947 CDS YP_001283728.1 148662205 5212584 complement(2664807..2665955) 1 NC_009525.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 2665955 dnaJ2 5212584 dnaJ2 Mycobacterium tuberculosis H37Ra molecular chaperone DnaJ YP_001283728.1 2664807 R 419947 CDS YP_001283729.1 148662206 5212585 complement(2666030..2667061) 1 NC_009525.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 2667061 hrcA 5212585 hrcA Mycobacterium tuberculosis H37Ra heat-inducible transcription repressor YP_001283729.1 2666030 R 419947 CDS YP_001283730.1 148662207 5213895 2667233..2667550 1 NC_009525.1 hypothetical protein 2667550 5213895 MRA_2398 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283730.1 2667233 D 419947 CDS YP_001283731.1 148662208 5213896 complement(2667577..2668083) 1 NC_009525.1 antigen Cfp2 2668083 cfp2 5213896 cfp2 Mycobacterium tuberculosis H37Ra antigen Cfp2 YP_001283731.1 2667577 R 419947 CDS YP_001283732.1 148662209 5213897 complement(2668183..2668398) 1 NC_009525.1 protein MbtH 2668398 mbtH 5213897 mbtH Mycobacterium tuberculosis H37Ra protein MbtH YP_001283732.1 2668183 R 419947 CDS YP_001283733.1 148662210 5213898 complement(2668376..2669671) 1 NC_009525.1 lysine-N-oxygenase Mbtg 2669671 mbtG 5213898 mbtG Mycobacterium tuberculosis H37Ra lysine-N-oxygenase Mbtg YP_001283733.1 2668376 R 419947 CDS YP_001283734.1 148662211 5213899 complement(2669668..2674053) 1 NC_009525.1 peptide synthetase 2674053 mbtF 5213899 mbtF Mycobacterium tuberculosis H37Ra peptide synthetase YP_001283734.1 2669668 R 419947 CDS YP_001283735.1 148662212 5213900 complement(2674035..2679083) 1 NC_009525.1 peptide synthetase 2679083 mbtE 5213900 mbtE Mycobacterium tuberculosis H37Ra peptide synthetase YP_001283735.1 2674035 R 419947 CDS YP_001283736.1 148662213 5213901 complement(2679223..2682237) 1 NC_009525.1 polyketide synthase MbtD 2682237 mbtD 5213901 mbtD Mycobacterium tuberculosis H37Ra polyketide synthase MbtD YP_001283736.1 2679223 R 419947 CDS YP_001283737.1 148662214 5213902 complement(2682237..2683571) 1 NC_009525.1 polyketide synthase 2683571 mbtC 5213902 mbtC Mycobacterium tuberculosis H37Ra polyketide synthase YP_001283737.1 2682237 R 419947 CDS YP_001283738.1 148662215 5214000 complement(2683561..2687805) 1 NC_009525.1 dihydroaeruginoic acid synthetase 2687805 mbtB 5214000 mbtB Mycobacterium tuberculosis H37Ra dihydroaeruginoic acid synthetase YP_001283738.1 2683561 R 419947 CDS YP_001283739.1 148662216 5214001 2687904..2689601 1 NC_009525.1 2,3-dihydroxybenzoate-AMP ligase 2689601 mbtA 5214001 mbtA Mycobacterium tuberculosis H37Ra 2,3-dihydroxybenzoate-AMP ligase YP_001283739.1 2687904 D 419947 CDS YP_001283740.1 148662217 5214002 2689697..2690617 1 NC_009525.1 acetyl hydrolase MbtJ 2690617 mbtJ 5214002 mbtJ Mycobacterium tuberculosis H37Ra acetyl hydrolase MbtJ YP_001283740.1 2689697 D 419947 CDS YP_001283741.1 148662218 5214003 complement(2690621..2691973) 1 NC_009525.1 catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function; salicylate synthase MbtI 2691973 mbtI 5214003 mbtI Mycobacterium tuberculosis H37Ra salicylate synthase MbtI YP_001283741.1 2690621 R 419947 CDS YP_001283742.1 148662219 5214004 2692426..2692635 1 NC_009525.1 hypothetical protein 2692635 5214004 MRA_2410 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283742.1 2692426 D 419947 CDS YP_001283743.1 148662220 5214005 2692733..2693986 1 NC_009525.1 hypothetical protein 2693986 5214005 MRA_2411 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283743.1 2692733 D 419947 CDS YP_001283744.1 148662221 5214006 complement(2693983..2695110) 1 NC_009525.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 2695110 hemN 5214006 hemN Mycobacterium tuberculosis H37Ra coproporphyrinogen III oxidase YP_001283744.1 2693983 R 419947 CDS YP_001283745.1 148662222 5214007 complement(2695216..2695680) 1 NC_009525.1 resuscitation-promoting factor RpfD 2695680 rpfD 5214007 rpfD Mycobacterium tuberculosis H37Ra resuscitation-promoting factor RpfD YP_001283745.1 2695216 R 419947 CDS YP_001283746.1 148662223 5213170 complement(2695677..2696234) 1 NC_009525.1 hypothetical protein 2696234 5213170 MRA_2414 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283746.1 2695677 R 419947 CDS YP_001283747.1 148662224 5213171 2696647..2698338 1 NC_009525.1 nitrite reductase 2698338 nirA 5213171 nirA Mycobacterium tuberculosis H37Ra nitrite reductase YP_001283747.1 2696647 D 419947 CDS YP_001283748.1 148662225 5213172 2698335..2699099 1 NC_009525.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 2699099 cysH 5213172 cysH Mycobacterium tuberculosis H37Ra phosphoadenosine phosphosulfate reductase YP_001283748.1 2698335 D 419947 CDS YP_001283749.1 148662226 5213173 2699096..2699941 1 NC_009525.1 hypothetical protein 2699941 5213173 MRA_2417 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283749.1 2699096 D 419947 CDS YP_001283750.1 148662227 5213174 2699978..2701909 1 NC_009525.1 gamma-glutamyltranspeptidase precursor GgtB 2701909 ggtB 5213174 ggtB Mycobacterium tuberculosis H37Ra gamma-glutamyltranspeptidase precursor GgtB YP_001283750.1 2699978 D 419947 CDS YP_001283751.1 148662228 5213175 2702040..2704043 1 NC_009525.1 integral membrane protein 2704043 5213175 MRA_2419 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283751.1 2702040 D 419947 CDS YP_001283752.1 148662229 5213176 2704767..2705852 1 NC_009525.1 PE-PGRS family protein 2705852 5213176 MRA_2420 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283752.1 2704767 D 419947 CDS YP_001283753.1 148662230 5213177 complement(2705877..2706932) 1 NC_009525.1 sulfate ABC transporter ATP-binding protein CysA1 2706932 cysA1 5213177 cysA1 Mycobacterium tuberculosis H37Ra sulfate ABC transporter ATP-binding protein CysA1 YP_001283753.1 2705877 R 419947 CDS YP_001283754.1 148662231 5213218 complement(2706949..2707767) 1 NC_009525.1 sulfate ABC transporter permease CysW 2707767 cysW 5213218 cysW Mycobacterium tuberculosis H37Ra sulfate ABC transporter permease CysW YP_001283754.1 2706949 R 419947 CDS YP_001283755.1 148662232 5213219 complement(2707764..2708615) 1 NC_009525.1 sulfate ABC transporter permease CysT 2708615 cysT 5213219 cysT Mycobacterium tuberculosis H37Ra sulfate ABC transporter permease CysT YP_001283755.1 2707764 R 419947 CDS YP_001283756.1 148662233 5213220 complement(2708612..2709682) 1 NC_009525.1 sulfate ABC transporter substrate-binding protein 2709682 subI 5213220 subI Mycobacterium tuberculosis H37Ra sulfate ABC transporter substrate-binding protein YP_001283756.1 2708612 R 419947 CDS YP_001283757.1 148662234 5213221 complement(2710010..2710213) 1 NC_009525.1 hypothetical protein 2710213 5213221 MRA_2425 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283757.1 2710010 R 419947 CDS YP_001283758.1 148662235 5213222 2710497..2712425 1 NC_009525.1 hypothetical protein 2712425 5213222 MRA_2426 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283758.1 2710497 D 419947 CDS YP_001283759.1 148662236 5213223 complement(2712503..2713258) 1 NC_009525.1 lipoprotein LppR 2713258 lppR 5213223 lppR Mycobacterium tuberculosis H37Ra lipoprotein LppR YP_001283759.1 2712503 R 419947 CDS YP_001283760.1 148662237 5213224 complement(2713255..2715216) 1 NC_009525.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2715216 lepA 5213224 lepA Mycobacterium tuberculosis H37Ra GTP-binding protein LepA YP_001283760.1 2713255 R 419947 CDS YP_001283761.1 148662238 5213225 2715237..2715806 1 NC_009525.1 hypothetical protein 2715806 5213225 MRA_2429 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283761.1 2715237 D 419947 CDS YP_001283762.1 148662239 5213226 complement(2715977..2716405) 1 NC_009525.1 hypothetical protein 2716405 5213226 MRA_2430 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283762.1 2715977 R 419947 CDS YP_001283763.1 148662240 5212418 2716665..2717486 1 NC_009525.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2717486 5212418 MRA_2431 Mycobacterium tuberculosis H37Ra ribonuclease Z YP_001283763.1 2716665 D 419947 CDS YP_001283764.1 148662241 5212419 complement(2717454..2717726) 1 NC_009525.1 hypothetical protein 2717726 5212419 MRA_2432 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283764.1 2717454 R 419947 CDS YP_001283765.1 148662242 5212420 2717730..2718704 1 NC_009525.1 PE family protein 2718704 5212420 MRA_2433 Mycobacterium tuberculosis H37Ra PE family protein YP_001283765.1 2717730 D 419947 CDS YP_001283766.1 148662243 5212421 complement(2718462..2719301) 1 NC_009525.1 hypothetical protein 2719301 5212421 MRA_2434 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283766.1 2718462 R 419947 CDS YP_001283767.1 148662244 5212422 complement(2719301..2720278) 1 NC_009525.1 hypothetical protein 2720278 5212422 MRA_2435 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283767.1 2719301 R 419947 CDS YP_001283768.1 148662245 5212423 complement(2720278..2721933) 1 NC_009525.1 hypothetical protein 2721933 5212423 MRA_2436 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283768.1 2720278 R 419947 CDS YP_001283769.1 148662246 5212424 2722043..2722303 1 NC_009525.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2722303 rpsT 5212424 rpsT Mycobacterium tuberculosis H37Ra 30S ribosomal protein S20 YP_001283769.1 2722043 D 419947 CDS YP_001283770.1 148662247 5212425 complement(2722319..2723269) 1 NC_009525.1 hypothetical protein 2723269 5212425 MRA_2438 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283770.1 2722319 R 419947 CDS YP_001283771.1 148662248 5212426 complement(2723300..2724844) 1 NC_009525.1 hypothetical protein 2724844 5212426 MRA_2439 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283771.1 2723300 R 419947 CDS YP_001283772.1 148662249 5212885 complement(2724859..2725752) 1 NC_009525.1 hypothetical protein 2725752 5212885 MRA_2440 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283772.1 2724859 R 419947 CDS YP_001283773.1 148662250 5212886 complement(2726092..2727300) 1 NC_009525.1 hypothetical protein 2727300 eis 5212886 eis Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283773.1 2726092 R 419947 CDS YP_001283774.1 148662251 5212887 complement(2727440..2728282) 1 NC_009525.1 hypothetical protein 2728282 5212887 MRA_2443 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283774.1 2727440 R 419947 CDS YP_001283775.1 148662252 5212888 complement(2728363..2729106) 1 NC_009525.1 hypothetical protein 2729106 5212888 MRA_2444 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283775.1 2728363 R 419947 CDS YP_001283776.1 148662253 5212889 complement(2729096..2729767) 1 NC_009525.1 phosphoglycerate mutase 2729767 5212889 MRA_2445 Mycobacterium tuberculosis H37Ra phosphoglycerate mutase YP_001283776.1 2729096 R 419947 CDS YP_001283777.1 148662254 5212890 complement(2729764..2730144) 1 NC_009525.1 iojap-related protein 2730144 5212890 MRA_2446 Mycobacterium tuberculosis H37Ra iojap-related protein YP_001283777.1 2729764 R 419947 CDS YP_001283778.1 148662255 5212891 complement(2730141..2730776) 1 NC_009525.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 2730776 nadD 5212891 nadD Mycobacterium tuberculosis H37Ra nicotinic acid mononucleotide adenylyltransferase YP_001283778.1 2730141 R 419947 CDS YP_001283779.1 148662256 5212892 2731051..2731323 1 NC_009525.1 hypothetical protein 2731323 5212892 MRA_2448 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283779.1 2731051 D 419947 CDS YP_001283780.1 148662257 5212893 2731565..2732611 1 NC_009525.1 hypothetical protein 2732611 5212893 MRA_2449 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283780.1 2731565 D 419947 CDS YP_001283781.1 148662258 5214576 complement(2732744..2733745) 1 NC_009525.1 transposase 2733745 5214576 MRA_2450 Mycobacterium tuberculosis H37Ra transposase YP_001283781.1 2732744 R 419947 CDS YP_001283782.1 148662259 5214577 complement(2733834..2735276) 1 NC_009525.1 hypothetical protein 2735276 5214577 MRA_2451 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283782.1 2733834 R 419947 CDS YP_001283783.1 148662260 5214578 complement(2735276..2736151) 1 NC_009525.1 hypothetical protein 2736151 5214578 MRA_2452 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283783.1 2735276 R 419947 CDS YP_001283784.1 148662261 5214579 complement(2736198..2737445) 1 NC_009525.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 2737445 proA 5214579 proA Mycobacterium tuberculosis H37Ra gamma-glutamyl phosphate reductase YP_001283784.1 2736198 R 419947 CDS YP_001283785.1 148662262 5214580 2737546..2737815 1 NC_009525.1 hypothetical protein 2737815 5214580 MRA_2454 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283785.1 2737546 D 419947 CDS YP_001283786.1 148662263 5214581 2738161..2738748 1 NC_009525.1 hypothetical protein 2738748 ahpC 5214581 ahpC Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283786.1 2738161 D 419947 CDS YP_001283787.1 148662264 5214582 2738774..2739307 1 NC_009525.1 alkyl hydroperoxide reductase D; AhpD 2739307 ahpD 5214582 ahpD Mycobacterium tuberculosis H37Ra AhpD YP_001283787.1 2738774 D 419947 CDS YP_001283788.1 148662265 5214583 complement(2739304..2739888) 1 NC_009525.1 PPE family protein 2739888 5214583 MRA_2457 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283788.1 2739304 R 419947 CDS YP_001283789.1 148662266 5214584 complement(2739935..2740234) 1 NC_009525.1 PE family protein 2740234 5214584 MRA_2458 Mycobacterium tuberculosis H37Ra PE family protein YP_001283789.1 2739935 R 419947 CDS YP_001283790.1 148662267 5212862 complement(2740405..2740815) 1 NC_009525.1 hypothetical protein 2740815 5212862 MRA_2458A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283790.1 2740405 R 419947 CDS YP_001283791.1 148662268 5212863 complement(2740812..2741102) 1 NC_009525.1 hypothetical protein 2741102 5212863 MRA_2459 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283791.1 2740812 R 419947 CDS YP_001283792.1 148662269 5212864 complement(2741083..2742528) 1 NC_009525.1 transmembrane protein 2742528 5212864 MRA_2460 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283792.1 2741083 R 419947 CDS YP_001283793.1 148662270 5212865 complement(2742525..2744717) 1 NC_009525.1 adenylate cyclase 2744717 5212865 MRA_2461 Mycobacterium tuberculosis H37Ra adenylate cyclase YP_001283793.1 2742525 R 419947 CDS YP_001283794.1 148662271 5212866 2745198..2746112 1 NC_009525.1 ribokinase 2746112 rbsK 5212866 rbsK Mycobacterium tuberculosis H37Ra ribokinase YP_001283794.1 2745198 D 419947 CDS YP_001283795.1 148662272 5212867 2746344..2746763 1 NC_009525.1 hypothetical protein 2746763 5212867 MRA_2463 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283795.1 2746344 D 419947 CDS YP_001283796.1 148662273 5212868 complement(2746760..2748799) 1 NC_009525.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2748799 nadE 5212868 nadE Mycobacterium tuberculosis H37Ra NAD synthetase YP_001283796.1 2746760 R 419947 CDS YP_001283797.1 148662274 5212869 complement(2749085..2750215) 1 NC_009525.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 2750215 proB 5212869 proB Mycobacterium tuberculosis H37Ra gamma-glutamyl kinase YP_001283797.1 2749085 R 419947 CDS YP_001283798.1 148662275 5212870 complement(2750215..2751654) 1 NC_009525.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 2751654 obgE 5212870 obgE Mycobacterium tuberculosis H37Ra GTPase ObgE YP_001283798.1 2750215 R 419947 CDS YP_001283799.1 148662276 5214825 complement(2751740..2752000) 1 NC_009525.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 2752000 rpmA 5214825 rpmA Mycobacterium tuberculosis H37Ra 50S ribosomal protein L27 YP_001283799.1 2751740 R 419947 CDS YP_001283800.1 148662277 5214826 complement(2752015..2752329) 1 NC_009525.1 50S ribosomal protein L21 2752329 rplU 5214826 rplU Mycobacterium tuberculosis H37Ra 50S ribosomal protein L21 YP_001283800.1 2752015 R 419947 CDS YP_001283801.1 148662278 5214827 2752677..2754152 1 NC_009525.1 C4-dicarboxylate transport protein 2754152 dctA 5214827 dctA Mycobacterium tuberculosis H37Ra C4-dicarboxylate transport protein YP_001283801.1 2752677 D 419947 CDS YP_001283802.1 148662279 5214828 complement(2754091..2756952) 1 NC_009525.1 cytoplasmic axial filament protein 2756952 rne 5214828 rne Mycobacterium tuberculosis H37Ra cytoplasmic axial filament protein YP_001283802.1 2754091 R 419947 CDS YP_001283803.1 148662280 5214829 complement(2757282..2757692) 1 NC_009525.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2757692 ndk 5214829 ndk Mycobacterium tuberculosis H37Ra nucleoside diphosphate kinase YP_001283803.1 2757282 R 419947 CDS YP_001283804.1 148662281 5214830 complement(2757735..2758106) 1 NC_009525.1 integral membrane protein 2758106 5214830 MRA_2472 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283804.1 2757735 R 419947 CDS YP_001283805.1 148662282 5214831 complement(2758103..2759566) 1 NC_009525.1 folylpolyglutamate synthase 2759566 folC 5214831 folC Mycobacterium tuberculosis H37Ra folylpolyglutamate synthase YP_001283805.1 2758103 R 419947 CDS YP_001283806.1 148662283 5214832 complement(2759563..2762193) 1 NC_009525.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 2762193 valS 5214832 valS Mycobacterium tuberculosis H37Ra valyl-tRNA synthetase YP_001283806.1 2759563 R 419947 CDS YP_001283807.1 148662284 5214833 complement(2762281..2763540) 1 NC_009525.1 hypothetical protein 2763540 5214833 MRA_2475 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283807.1 2762281 R 419947 CDS YP_001283808.1 148662285 5213026 complement(2763630..2764148) 1 NC_009525.1 resuscitation-promoting factor RpfE 2764148 rpfE 5213026 rpfE Mycobacterium tuberculosis H37Ra resuscitation-promoting factor RpfE YP_001283808.1 2763630 R 419947 CDS YP_001283809.1 148662286 5213027 2764230..2764628 1 NC_009525.1 hypothetical protein 2764628 5213027 MRA_2477 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283809.1 2764230 D 419947 CDS YP_001283810.1 148662287 5213028 complement(2764816..2764962) 1 NC_009525.1 hypothetical protein 2764962 5213028 MRA_2478 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283810.1 2764816 R 419947 CDS YP_001283811.1 148662288 5213029 complement(2764986..2765591) 1 NC_009525.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 2765591 mobA 5213029 mobA Mycobacterium tuberculosis H37Ra molybdopterin-guanine dinucleotide biosynthesis protein A YP_001283811.1 2764986 R 419947 CDS YP_001283812.1 148662289 5213030 complement(2765593..2766714) 1 NC_009525.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 2766714 5213030 MRA_2480 Mycobacterium tuberculosis H37Ra 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_001283812.1 2765593 R 419947 CDS YP_001283813.1 148662290 5213031 complement(2766711..2768672) 1 NC_009525.1 ferredoxin oxidoreductase subunit alpha 2768672 5213031 MRA_2481 Mycobacterium tuberculosis H37Ra ferredoxin oxidoreductase subunit alpha YP_001283813.1 2766711 R 419947 CDS YP_001283814.1 148662291 5213032 complement(2768904..2770160) 1 NC_009525.1 integral membrane transport protein 2770160 5213032 MRA_2482 Mycobacterium tuberculosis H37Ra integral membrane transport protein YP_001283814.1 2768904 R 419947 CDS YP_001283815.1 148662292 5213033 complement(2770176..2771456) 1 NC_009525.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 2771456 clpX 5213033 clpX Mycobacterium tuberculosis H37Ra ATP-dependent protease ATP-binding subunit ClpX YP_001283815.1 2770176 R 419947 CDS YP_001283816.1 148662293 5213034 2771747..2772655 1 NC_009525.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 2772655 mmuM 5213034 mmuM Mycobacterium tuberculosis H37Ra homocysteine methyltransferase YP_001283816.1 2771747 D 419947 CDS YP_001283817.1 148662294 5211963 2772822..2774348 1 NC_009525.1 transmembrane transport protein 2774348 5211963 MRA_2485 Mycobacterium tuberculosis H37Ra transmembrane transport protein YP_001283817.1 2772822 D 419947 CDS YP_001283818.1 148662295 5211964 complement(2774499..2775143) 1 NC_009525.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2775143 clpP2 5211964 clpP2 Mycobacterium tuberculosis H37Ra ATP-dependent Clp protease proteolytic subunit YP_001283818.1 2774499 R 419947 CDS YP_001283819.1 148662296 5211965 complement(2775140..2775742) 1 NC_009525.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2775742 clpP 5211965 clpP Mycobacterium tuberculosis H37Ra ATP-dependent Clp protease proteolytic subunit YP_001283819.1 2775140 R 419947 CDS YP_001283820.1 148662297 5211966 complement(2775859..2777259) 1 NC_009525.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 2777259 tig 5211966 tig Mycobacterium tuberculosis H37Ra trigger factor YP_001283820.1 2775859 R 419947 CDS YP_001283821.1 148662298 5211969 2777623..2778807 1 NC_009525.1 esterase 2778807 lipP 5211969 lipP Mycobacterium tuberculosis H37Ra esterase YP_001283821.1 2777623 D 419947 CDS YP_001283822.1 148662299 5215007 complement(2778827..2779633) 1 NC_009525.1 formamidopyrimidine-DNA glycosylase 2779633 5215007 MRA_2490 Mycobacterium tuberculosis H37Ra formamidopyrimidine-DNA glycosylase YP_001283822.1 2778827 R 419947 CDS YP_001283823.1 148662300 5215008 complement(2779639..2780127) 1 NC_009525.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 2780127 5215008 MRA_2491 Mycobacterium tuberculosis H37Ra ribose-5-phosphate isomerase B YP_001283823.1 2779639 R 419947 CDS YP_001283824.1 148662301 5215009 2780199..2781005 1 NC_009525.1 hypothetical protein 2781005 5215009 MRA_2492 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283824.1 2780199 D 419947 CDS YP_001283825.1 148662302 5215010 2780954..2783539 1 NC_009525.1 aminopeptidase 2783539 pepN 5215010 pepN Mycobacterium tuberculosis H37Ra aminopeptidase YP_001283825.1 2780954 D 419947 CDS YP_001283826.1 148662303 5215011 complement(2783612..2784115) 1 NC_009525.1 hypothetical protein 2784115 5215011 MRA_2494 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283826.1 2783612 R 419947 CDS YP_001283827.1 148662304 5215012 complement(2784335..2785003) 1 NC_009525.1 hypothetical protein 2785003 5215012 MRA_2495 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283827.1 2784335 R 419947 CDS YP_001283828.1 148662305 5215013 2785146..2785532 1 NC_009525.1 hypothetical protein 2785532 glbO 5215013 glbO Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283828.1 2785146 D 419947 CDS YP_001283829.1 148662306 5213374 2785532..2787172 1 NC_009525.1 alpha-glucosidase 2787172 aglA 5213374 aglA Mycobacterium tuberculosis H37Ra alpha-glucosidase YP_001283829.1 2785532 D 419947 CDS YP_001283830.1 148662307 5213375 2787240..2787533 1 NC_009525.1 hypothetical protein 2787533 5213375 MRA_2498 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283830.1 2787240 D 419947 CDS YP_001283831.1 148662308 5213376 2787536..2788252 1 NC_009525.1 hypothetical protein 2788252 5213376 MRA_2499 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283831.1 2787536 D 419947 CDS YP_001283832.1 148662309 5213377 complement(2788284..2788937) 1 NC_009525.1 hypothetical protein 2788937 5213377 MRA_2500 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283832.1 2788284 R 419947 CDS YP_001283833.1 148662310 5213378 complement(2788943..2789359) 1 NC_009525.1 hypothetical protein 2789359 5213378 MRA_2500A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283833.1 2788943 R 419947 CDS YP_001283834.1 148662311 5213379 complement(2789356..2794230) 1 NC_009525.1 NAD-dependent glutamate dehydrogenase Gdh 2794230 gdh 5213379 gdh Mycobacterium tuberculosis H37Ra NAD-dependent glutamate dehydrogenase Gdh YP_001283834.1 2789356 R 419947 CDS YP_001283835.1 148662312 5213380 complement(2794334..2796010) 1 NC_009525.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 2796010 5213380 MRA_2502 Mycobacterium tuberculosis H37Ra ABC transporter ATP-binding protein YP_001283835.1 2794334 R 419947 CDS YP_001283836.1 148662313 5213381 complement(2796091..2796576) 1 NC_009525.1 hypothetical protein 2796576 5213381 MRA_2503 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283836.1 2796091 R 419947 CDS YP_001283837.1 148662314 5213382 complement(2796625..2797509) 1 NC_009525.1 IS6110 transposase 2797509 5213382 MRA_2504 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001283837.1 2796625 R 419947 CDS YP_001283838.1 148662315 5213853 complement(2797560..2797886) 1 NC_009525.1 IS6110 hypothetical protein 2797886 5213853 MRA_2505 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001283838.1 2797560 R 419947 CDS YP_001283839.1 148662316 5213854 complement(2798543..2798866) 1 NC_009525.1 hypothetical protein 2798866 5213854 MRA_2506 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283839.1 2798543 R 419947 CDS YP_001283840.1 148662317 5213855 complement(2798882..2801251) 1 NC_009525.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 2801251 plsB2 5213855 plsB2 Mycobacterium tuberculosis H37Ra glycerol-3-phosphate acyltransferase YP_001283840.1 2798882 R 419947 CDS YP_001283841.1 148662318 5213856 complement(2801248..2802990) 1 NC_009525.1 bifunctional transmembrane phospholipid biosynthesis enzyme PlsC 2802990 plsC 5213856 plsC Mycobacterium tuberculosis H37Ra bifunctional transmembrane phospholipid biosynthesis enzyme PlsC YP_001283841.1 2801248 R 419947 CDS YP_001283842.1 148662319 5213857 complement(2802987..2804462) 1 NC_009525.1 hypothetical protein 2804462 5213857 MRA_2509 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283842.1 2802987 R 419947 CDS YP_001283843.1 148662320 5213858 complement(2804691..2805956) 1 NC_009525.1 carboxylesterase LipQ 2805956 lipQ 5213858 lipQ Mycobacterium tuberculosis H37Ra carboxylesterase LipQ YP_001283843.1 2804691 R 419947 CDS YP_001283844.1 148662321 5213860 2806318..2807088 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2807088 echA14 5213860 echA14 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001283844.1 2806318 D 419947 CDS YP_001283845.1 148662322 5214135 complement(2807269..2809353) 1 NC_009525.1 PE-PGRS family protein 2809353 5214135 MRA_2512 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283845.1 2807269 R 419947 CDS YP_001283846.1 148662323 5214136 complement(2809435..2812848) 1 NC_009525.1 LuxR family transcriptional regulator 2812848 5214136 MRA_2513 Mycobacterium tuberculosis H37Ra LuxR family transcriptional regulator YP_001283846.1 2809435 R 419947 CDS YP_001283847.1 148662324 5214137 complement(2812814..2813113) 1 NC_009525.1 hypothetical protein 2813113 5214137 MRA_2514 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283847.1 2812814 R 419947 CDS YP_001283848.1 148662325 5214138 complement(2813222..2818204) 1 NC_009525.1 PE-PGRS family protein 2818204 5214138 MRA_2515 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283848.1 2813222 R 419947 CDS YP_001283849.1 148662326 5214139 complement(2818291..2818497) 1 NC_009525.1 hypothetical protein 2818497 5214139 MRA_2516 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283849.1 2818291 R 419947 CDS YP_001283850.1 148662327 5214140 2818633..2819256 1 NC_009525.1 hypothetical protein 2819256 5214140 MRA_2517 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283850.1 2818633 D 419947 CDS YP_001283851.1 148662328 5214141 2819246..2819998 1 NC_009525.1 hypothetical protein 2819998 5214141 MRA_2518 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283851.1 2819246 D 419947 CDS YP_001283852.1 148662329 5215208 2820051..2820272 1 NC_009525.1 hypothetical protein 2820272 5215208 MRA_2519 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283852.1 2820051 D 419947 CDS YP_001283853.1 148662330 5215209 2820278..2820703 1 NC_009525.1 hypothetical protein 2820703 5215209 MRA_2520 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283853.1 2820278 D 419947 CDS YP_001283854.1 148662331 5215210 complement(2820726..2821907) 1 NC_009525.1 branched-chain alpha-keto acid dehydrogenase subunit E2 2821907 pdhC 5215210 pdhC Mycobacterium tuberculosis H37Ra branched-chain alpha-keto acid dehydrogenase subunit E2 YP_001283854.1 2820726 R 419947 CDS YP_001283855.1 148662332 5215211 complement(2821904..2822950) 1 NC_009525.1 2-oxoisovalerate dehydrogenase E1 component subunit beta 2822950 pdhB 5215211 pdhB Mycobacterium tuberculosis H37Ra 2-oxoisovalerate dehydrogenase E1 component subunit beta YP_001283855.1 2821904 R 419947 CDS YP_001283856.1 148662333 5215212 complement(2822961..2824064) 1 NC_009525.1 2-oxoisovalerate dehydrogenase E1 component subunit alpha 2824064 pdhA 5215212 pdhA Mycobacterium tuberculosis H37Ra 2-oxoisovalerate dehydrogenase E1 component subunit alpha YP_001283856.1 2822961 R 419947 CDS YP_001283857.1 148662334 5215213 complement(2824323..2825144) 1 NC_009525.1 citrate lyase subunit beta 2825144 citE 5215213 citE Mycobacterium tuberculosis H37Ra citrate lyase subunit beta YP_001283857.1 2824323 R 419947 CDS YP_001283858.1 148662335 5215214 complement(2825141..2825698) 1 NC_009525.1 oxidase regulatory-related protein 2825698 5215214 MRA_2525 Mycobacterium tuberculosis H37Ra oxidase regulatory-related protein YP_001283858.1 2825141 R 419947 CDS YP_001283859.1 148662336 5215215 complement(2825695..2826879) 1 NC_009525.1 acyl-CoA dehydrogenase 2826879 fadE19 5215215 fadE19 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001283859.1 2825695 R 419947 CDS YP_001283860.1 148662337 5215216 complement(2826884..2828848) 1 NC_009525.1 acetyl-/propionyl-coenzyme A carboxylase subunit alpha 2828848 accA1 5215216 accA1 Mycobacterium tuberculosis H37Ra acetyl-/propionyl-coenzyme A carboxylase subunit alpha YP_001283860.1 2826884 R 419947 CDS YP_001283861.1 148662338 5215587 complement(2828853..2830442) 1 NC_009525.1 propionyl-CoA carboxylase subunit beta 2830442 accD1 5215587 accD1 Mycobacterium tuberculosis H37Ra propionyl-CoA carboxylase subunit beta YP_001283861.1 2828853 R 419947 CDS YP_001283862.1 148662339 5215588 complement(2830439..2831095) 1 NC_009525.1 succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B 2831095 scoB 5215588 scoB Mycobacterium tuberculosis H37Ra succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B YP_001283862.1 2830439 R 419947 CDS YP_001283863.1 148662340 5215589 complement(2831092..2831838) 1 NC_009525.1 succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A 2831838 scoA 5215589 scoA Mycobacterium tuberculosis H37Ra succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A YP_001283863.1 2831092 R 419947 CDS YP_001283864.1 148662341 5215590 complement(2831921..2833564) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; AMP-binding protein 2833564 fadD35 5215590 fadD35 Mycobacterium tuberculosis H37Ra AMP-binding protein YP_001283864.1 2831921 R 419947 CDS YP_001283865.1 148662342 5215591 2833680..2834327 1 NC_009525.1 TetR family transcriptional regulator 2834327 5215591 MRA_2532 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001283865.1 2833680 D 419947 CDS YP_001283866.1 148662343 5215592 2834406..2835227 1 NC_009525.1 hypothetical protein 2835227 5215592 MRA_2533 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283866.1 2834406 D 419947 CDS YP_001283867.1 148662344 5215593 complement(2835224..2836561) 1 NC_009525.1 leucine and alanine rich integral membrane protein 2836561 5215593 MRA_2534 Mycobacterium tuberculosis H37Ra leucine and alanine rich integral membrane protein YP_001283867.1 2835224 R 419947 CDS YP_001283868.1 148662345 5215594 2836646..2837452 1 NC_009525.1 short-chain type dehydrogenase/reductase 2837452 5215594 MRA_2535 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001283868.1 2836646 D 419947 CDS YP_001283869.1 148662346 5215595 complement(2837456..2839057) 1 NC_009525.1 hypothetical protein 2839057 5215595 MRA_2536 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283869.1 2837456 R 419947 CDS YP_001283870.1 148662347 5212246 2839125..2839772 1 NC_009525.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 2839772 orn 5212246 orn Mycobacterium tuberculosis H37Ra oligoribonuclease YP_001283870.1 2839125 D 419947 CDS YP_001283871.1 148662348 5212248 complement(2840524..2841771) 1 NC_009525.1 IS1081 transposase 2841771 5212248 MRA_2538 Mycobacterium tuberculosis H37Ra IS1081 transposase YP_001283871.1 2840524 R 419947 CDS YP_001283872.1 148662349 5212249 2841922..2842107 1 NC_009525.1 hypothetical protein 2842107 5212249 MRA_2539 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283872.1 2841922 D 419947 CDS YP_001283873.1 148662350 5212250 2842129..2842551 1 NC_009525.1 hypothetical protein 2842551 5212250 MRA_2540 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283873.1 2842129 D 419947 CDS YP_001283874.1 148662351 5212251 complement(2842845..2843306) 1 NC_009525.1 hypothetical protein 2843306 5212251 MRA_2541 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283874.1 2842845 R 419947 CDS YP_001283875.1 148662352 5212252 complement(2843312..2844559) 1 NC_009525.1 hypothetical protein 2844559 5212252 MRA_2542 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283875.1 2843312 R 419947 CDS YP_001283876.1 148662353 5212253 complement(2844678..2845481) 1 NC_009525.1 hypothetical protein 2845481 5212253 MRA_2543 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283876.1 2844678 R 419947 CDS YP_001283877.1 148662354 5214151 complement(2845478..2845729) 1 NC_009525.1 hypothetical protein 2845729 5214151 MRA_2544 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283877.1 2845478 R 419947 CDS YP_001283878.1 148662355 5214152 complement(2846077..2847303) 1 NC_009525.1 lipoprotein LppS 2847303 lppS 5214152 lppS Mycobacterium tuberculosis H37Ra lipoprotein LppS YP_001283878.1 2846077 R 419947 CDS YP_001283879.1 148662356 5214154 2847753..2849231 1 NC_009525.1 PE family protein 2849231 5214154 MRA_2546 Mycobacterium tuberculosis H37Ra PE family protein YP_001283879.1 2847753 D 419947 CDS YP_001283880.1 148662357 5214155 complement(2849356..2849583) 1 NC_009525.1 hypothetical protein 2849583 5214155 MRA_2547 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283880.1 2849356 R 419947 CDS YP_001283881.1 148662358 5214156 2849652..2850125 1 NC_009525.1 bacterioferritin comigratory protein Bcp 2850125 bcp 5214156 bcp Mycobacterium tuberculosis H37Ra bacterioferritin comigratory protein Bcp YP_001283881.1 2849652 D 419947 CDS YP_001283882.1 148662359 5214157 complement(2850097..2851509) 1 NC_009525.1 hypothetical protein 2851509 5214157 MRA_2549 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283882.1 2850097 R 419947 CDS YP_001283883.1 148662360 5214158 complement(2851506..2851898) 1 NC_009525.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2851898 acpS 5214158 acpS Mycobacterium tuberculosis H37Ra 4'-phosphopantetheinyl transferase YP_001283883.1 2851506 R 419947 CDS YP_001283884.1 148662361 5213489 complement(2852091..2861300) 1 NC_009525.1 fatty-acid synthase 2861300 fas 5213489 fas Mycobacterium tuberculosis H37Ra fatty-acid synthase YP_001283884.1 2852091 R 419947 CDS YP_001283885.1 148662362 5213490 complement(2861820..2862542) 1 NC_009525.1 hypothetical protein 2862542 5213490 MRA_2552 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283885.1 2861820 R 419947 CDS YP_001283886.1 148662363 5213491 2863059..2863286 1 NC_009525.1 hypothetical protein 2863286 5213491 MRA_2553 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283886.1 2863059 D 419947 CDS YP_001283887.1 148662364 5213492 2863283..2863684 1 NC_009525.1 hypothetical protein 2863684 5213492 MRA_2554 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283887.1 2863283 D 419947 CDS YP_001283888.1 148662365 5213493 complement(2863719..2864639) 1 NC_009525.1 restriction system protein Mrr 2864639 mrr 5213493 mrr Mycobacterium tuberculosis H37Ra restriction system protein Mrr YP_001283888.1 2863719 R 419947 CDS YP_001283889.1 148662366 5213494 2864843..2866234 1 NC_009525.1 hypothetical protein 2866234 5213494 MRA_2556 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283889.1 2864843 D 419947 CDS YP_001283890.1 148662367 5213495 complement(2866235..2866654) 1 NC_009525.1 hypothetical protein 2866654 5213495 MRA_2557 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283890.1 2866235 R 419947 CDS YP_001283891.1 148662368 5213496 complement(2866651..2866875) 1 NC_009525.1 hypothetical protein 2866875 5213496 MRA_2558 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283891.1 2866651 R 419947 CDS YP_001283892.1 148662369 5213497 complement(2866906..2869749) 1 NC_009525.1 Orn/Lys/Arg family decarboxylase 2869749 5213497 MRA_2559 Mycobacterium tuberculosis H37Ra Orn/Lys/Arg family decarboxylase YP_001283892.1 2866906 R 419947 CDS YP_001283893.1 148662370 5212720 complement(2869821..2870222) 1 NC_009525.1 hypothetical protein 2870222 5212720 MRA_2560 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283893.1 2869821 R 419947 CDS YP_001283894.1 148662371 5212721 complement(2870222..2870692) 1 NC_009525.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 2870692 nusB 5212721 nusB Mycobacterium tuberculosis H37Ra transcription antitermination protein NusB YP_001283894.1 2870222 R 419947 CDS YP_001283895.1 148662372 5212722 complement(2870695..2871258) 1 NC_009525.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 2871258 efp 5212722 efp Mycobacterium tuberculosis H37Ra elongation factor P YP_001283895.1 2870695 R 419947 CDS YP_001283896.1 148662373 5212723 complement(2871268..2872386) 1 NC_009525.1 Xaa-Pro dipeptidase 2872386 pepQ 5212723 pepQ Mycobacterium tuberculosis H37Ra Xaa-Pro dipeptidase YP_001283896.1 2871268 R 419947 CDS YP_001283897.1 148662374 5212724 2872420..2873112 1 NC_009525.1 transmembrane protein 2873112 5212724 MRA_2564 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283897.1 2872420 D 419947 CDS YP_001283898.1 148662375 5212725 complement(2873116..2873559) 1 NC_009525.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 2873559 aroD 5212725 aroD Mycobacterium tuberculosis H37Ra 3-dehydroquinate dehydratase YP_001283898.1 2873116 R 419947 CDS YP_001283899.1 148662376 5212726 complement(2873556..2874644) 1 NC_009525.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 2874644 aroB 5212726 aroB Mycobacterium tuberculosis H37Ra 3-dehydroquinate synthase YP_001283899.1 2873556 R 419947 CDS YP_001283900.1 148662377 5212727 complement(2874641..2875171) 1 NC_009525.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 2875171 aroK 5212727 aroK Mycobacterium tuberculosis H37Ra shikimate kinase YP_001283900.1 2874641 R 419947 CDS YP_001283901.1 148662378 5212728 complement(2875175..2876380) 1 NC_009525.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2876380 aroF 5212728 aroF Mycobacterium tuberculosis H37Ra chorismate synthase YP_001283901.1 2875175 R 419947 CDS YP_001283902.1 148662379 5212569 2876395..2876802 1 NC_009525.1 hypothetical protein 2876802 5212569 MRA_2569 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283902.1 2876395 D 419947 CDS YP_001283903.1 148662380 5212570 2877098..2878309 1 NC_009525.1 hypothetical protein 2878309 5212570 MRA_2570 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283903.1 2877098 D 419947 CDS YP_001283904.1 148662381 5212571 2878436..2879095 1 NC_009525.1 lipoprotein LppA 2879095 lppA 5212571 lppA Mycobacterium tuberculosis H37Ra lipoprotein LppA YP_001283904.1 2878436 D 419947 CDS YP_001283905.1 148662382 5212572 2879092..2879754 1 NC_009525.1 lipoprotein LppB 2879754 lppB 5212572 lppB Mycobacterium tuberculosis H37Ra lipoprotein LppB YP_001283905.1 2879092 D 419947 CDS YP_001283906.1 148662383 5212573 2879751..2880029 1 NC_009525.1 hypothetical protein 2880029 5212573 MRA_2573 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283906.1 2879751 D 419947 CDS YP_001283907.1 148662384 5212574 2880122..2880535 1 NC_009525.1 hypothetical protein 2880535 5212574 MRA_2574 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283907.1 2880122 D 419947 CDS YP_001283908.1 148662385 5212575 2880574..2880831 1 NC_009525.1 hypothetical protein 2880831 5212575 MRA_2575 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283908.1 2880574 D 419947 CDS YP_001283909.1 148662386 5212576 2880828..2881205 1 NC_009525.1 hypothetical protein 2881205 5212576 MRA_2576 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283909.1 2880828 D 419947 CDS YP_001283910.1 148662387 5212577 complement(2881221..2881595) 1 NC_009525.1 hypothetical protein 2881595 5212577 MRA_2577 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283910.1 2881221 R 419947 CDS YP_001283911.1 148662388 5212633 complement(2881695..2882090) 1 NC_009525.1 hypothetical protein 2882090 5212633 MRA_2578 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283911.1 2881695 R 419947 CDS YP_001283912.1 148662389 5212634 complement(2882087..2882332) 1 NC_009525.1 hypothetical protein 2882332 5212634 MRA_2579 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283912.1 2882087 R 419947 CDS YP_001283913.1 148662390 5212635 complement(2882743..2883162) 1 NC_009525.1 hypothetical protein 2883162 5212635 MRA_2580 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283913.1 2882743 R 419947 CDS YP_001283914.1 148662391 5212636 complement(2883174..2883983) 1 NC_009525.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 2883983 aroE 5212636 aroE Mycobacterium tuberculosis H37Ra shikimate 5-dehydrogenase YP_001283914.1 2883174 R 419947 CDS YP_001283915.1 148662392 5212637 complement(2883980..2885233) 1 NC_009525.1 hypothetical protein 2885233 5212637 MRA_2582 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283915.1 2883980 R 419947 CDS YP_001283916.1 148662393 5212638 complement(2885226..2885738) 1 NC_009525.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2885738 5212638 MRA_2583 Mycobacterium tuberculosis H37Ra Holliday junction resolvase-like protein YP_001283916.1 2885226 R 419947 CDS YP_001283917.1 148662394 5212639 complement(2885739..2888453) 1 NC_009525.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2888453 alaS 5212639 alaS Mycobacterium tuberculosis H37Ra alanyl-tRNA synthetase YP_001283917.1 2885739 R 419947 CDS YP_001283918.1 148662395 5212640 complement(2888544..2888933) 1 NC_009525.1 hypothetical protein 2888933 5212640 MRA_2585 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283918.1 2888544 R 419947 CDS YP_001283919.1 148662396 5212641 2889040..2889714 1 NC_009525.1 hypothetical protein 2889714 5212641 MRA_2586 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283919.1 2889040 D 419947 CDS YP_001283920.1 148662397 5213861 2889799..2890509 1 NC_009525.1 hypothetical protein 2890509 5213861 MRA_2587 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283920.1 2889799 D 419947 CDS YP_001283921.1 148662398 5213862 complement(2890539..2891897) 1 NC_009525.1 recombination factor protein RarA 2891897 5213862 MRA_2588 Mycobacterium tuberculosis H37Ra recombination factor protein RarA YP_001283921.1 2890539 R 419947 CDS YP_001283922.1 148662399 5213863 2892043..2893020 1 NC_009525.1 proline and glycine rich transmembrane protein 2893020 5213863 MRA_2589 Mycobacterium tuberculosis H37Ra proline and glycine rich transmembrane protein YP_001283922.1 2892043 D 419947 CDS YP_001283923.1 148662400 5213864 complement(2892933..2893256) 1 NC_009525.1 hypothetical protein 2893256 5213864 MRA_2590 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283923.1 2892933 R 419947 CDS YP_001283924.1 148662401 5213865 2893585..2894115 1 NC_009525.1 hypothetical protein 2894115 5213865 MRA_2591 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283924.1 2893585 D 419947 CDS YP_001283925.1 148662402 5213866 2894258..2895307 1 NC_009525.1 glutamine ABC transporter permease 2895307 5213866 MRA_2592 Mycobacterium tuberculosis H37Ra glutamine ABC transporter permease YP_001283925.1 2894258 D 419947 CDS YP_001283926.1 148662403 5213867 2895310..2896302 1 NC_009525.1 glutamine ABC transporter ATP-binding protein GlnQ 2896302 glnQ2 5213867 glnQ2 Mycobacterium tuberculosis H37Ra glutamine ABC transporter ATP-binding protein GlnQ YP_001283926.1 2895310 D 419947 CDS YP_001283927.1 148662404 5213868 2896579..2898330 1 NC_009525.1 hypothetical protein 2898330 5213868 MRA_2594 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283927.1 2896579 D 419947 CDS YP_001283928.1 148662405 5213869 2898341..2901763 1 NC_009525.1 transglutaminase 2901763 5213869 MRA_2595 Mycobacterium tuberculosis H37Ra transglutaminase YP_001283928.1 2898341 D 419947 CDS YP_001283929.1 148662406 5213185 2901763..2904417 1 NC_009525.1 hypothetical protein 2904417 5213185 MRA_2596 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283929.1 2901763 D 419947 CDS YP_001283930.1 148662407 5213186 complement(2904414..2905439) 1 NC_009525.1 hypothetical protein 2905439 5213186 MRA_2597 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283930.1 2904414 R 419947 CDS YP_001283931.1 148662408 5213187 complement(2905432..2906376) 1 NC_009525.1 hypothetical protein 2906376 5213187 MRA_2598 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283931.1 2905432 R 419947 CDS YP_001283932.1 148662409 5213188 2906480..2906869 1 NC_009525.1 hypothetical protein 2906869 5213188 MRA_2599 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283932.1 2906480 D 419947 CDS YP_001283933.1 148662410 5213189 complement(2906861..2907928) 1 NC_009525.1 alanine,valine and leucine rich transmembrane protein 2907928 5213189 MRA_2600 Mycobacterium tuberculosis H37Ra alanine,valine and leucine rich transmembrane protein YP_001283933.1 2906861 R 419947 CDS YP_001283934.1 148662411 5213190 complement(2907981..2909771) 1 NC_009525.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2909771 aspS 5213190 aspS Mycobacterium tuberculosis H37Ra aspartyl-tRNA synthetase YP_001283934.1 2907981 R 419947 CDS YP_001283935.1 148662412 5213191 2910011..2910751 1 NC_009525.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2910751 5213191 MRA_2602 Mycobacterium tuberculosis H37Ra 2-dehydropantoate 2-reductase YP_001283935.1 2910011 D 419947 CDS YP_001283936.1 148662413 5213192 2910774..2911277 1 NC_009525.1 hypothetical protein 2911277 5213192 MRA_2603 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283936.1 2910774 D 419947 CDS YP_001283937.1 148662414 5213193 2911307..2912188 1 NC_009525.1 glycine rich membrane protein 2912188 5213193 MRA_2604 Mycobacterium tuberculosis H37Ra glycine rich membrane protein YP_001283937.1 2911307 D 419947 CDS YP_001283938.1 148662415 5213480 complement(2912194..2912658) 1 NC_009525.1 hypothetical protein 2912658 5213480 MRA_2605 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283938.1 2912194 R 419947 CDS YP_001283939.1 148662416 5213481 2912886..2914475 1 NC_009525.1 hypothetical protein 2914475 5213481 MRA_2606 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283939.1 2912886 D 419947 CDS YP_001283940.1 148662417 5213482 complement(2914477..2915499) 1 NC_009525.1 hypothetical protein 2915499 5213482 MRA_2607 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283940.1 2914477 R 419947 CDS YP_001283941.1 148662418 5213483 2915607..2916509 1 NC_009525.1 catalyzes the cleavage of carbon-halogen bonds in aliphatic compounds forming a primary alcohol and a halide; haloalkane dehalogenase 2916509 dhaA 5213483 dhaA Mycobacterium tuberculosis H37Ra haloalkane dehalogenase YP_001283941.1 2915607 D 419947 CDS YP_001283942.1 148662419 5213484 complement(2916789..2918060) 1 NC_009525.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2918060 hisS 5213484 hisS Mycobacterium tuberculosis H37Ra histidyl-tRNA synthetase YP_001283942.1 2916789 R 419947 CDS YP_001283943.1 148662420 5213485 complement(2918057..2918731) 1 NC_009525.1 glyoxalase II 2918731 5213485 MRA_2610 Mycobacterium tuberculosis H37Ra glyoxalase II YP_001283943.1 2918057 R 419947 CDS YP_001283944.1 148662421 5213486 2918782..2919708 1 NC_009525.1 peptidyl-prolyl cis-trans isomerase B 2919708 ppiB 5213486 ppiB Mycobacterium tuberculosis H37Ra peptidyl-prolyl cis-trans isomerase B YP_001283944.1 2918782 D 419947 CDS YP_001283945.1 148662422 5213487 complement(2919794..2922166) 1 NC_009525.1 GTP pyrophosphokinase 2922166 relA 5213487 relA Mycobacterium tuberculosis H37Ra GTP pyrophosphokinase YP_001283945.1 2919794 R 419947 CDS YP_001283946.1 148662423 5213488 complement(2922197..2922868) 1 NC_009525.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 2922868 apt 5213488 apt Mycobacterium tuberculosis H37Ra adenine phosphoribosyltransferase YP_001283946.1 2922197 R 419947 CDS YP_001283947.1 148662424 5213310 complement(2922972..2924645) 1 NC_009525.1 ABC transporter substrate-binding protein 2924645 5213310 MRA_2614 Mycobacterium tuberculosis H37Ra ABC transporter substrate-binding protein YP_001283947.1 2922972 R 419947 CDS YP_001283948.1 148662425 5213311 complement(2924651..2925979) 1 NC_009525.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 2925979 secF 5213311 secF Mycobacterium tuberculosis H37Ra preprotein translocase subunit SecF YP_001283948.1 2924651 R 419947 CDS YP_001283949.1 148662426 5213312 complement(2925983..2927704) 1 NC_009525.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 2927704 secD 5213312 secD Mycobacterium tuberculosis H37Ra preprotein translocase subunit SecD YP_001283949.1 2925983 R 419947 CDS YP_001283950.1 148662427 5213313 complement(2927814..2928161) 1 NC_009525.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 2928161 yajC 5213313 yajC Mycobacterium tuberculosis H37Ra preprotein translocase subunit YajC YP_001283950.1 2927814 R 419947 CDS YP_001283951.1 148662428 5213314 2928328..2929677 1 NC_009525.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2929677 gabT 5213314 gabT Mycobacterium tuberculosis H37Ra 4-aminobutyrate aminotransferase YP_001283951.1 2928328 D 419947 CDS YP_001283952.1 148662429 5213315 2929839..2933345 1 NC_009525.1 fatty-acid--CoA ligase 2933345 fadD9 5213315 fadD9 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001283952.1 2929839 D 419947 CDS YP_001283953.1 148662430 5213316 2933489..2935150 1 NC_009525.1 PE-PGRS family protein 2935150 5213316 MRA_2620 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283953.1 2933489 D 419947 CDS YP_001283954.1 148662431 5213317 complement(2935167..2936201) 1 NC_009525.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2936201 ruvB 5213317 ruvB Mycobacterium tuberculosis H37Ra Holliday junction DNA helicase RuvB YP_001283954.1 2935167 R 419947 CDS YP_001283955.1 148662432 5213318 complement(2936198..2936788) 1 NC_009525.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2936788 ruvA 5213318 ruvA Mycobacterium tuberculosis H37Ra Holliday junction DNA helicase RuvA YP_001283955.1 2936198 R 419947 CDS YP_001283956.1 148662433 5213399 complement(2936785..2937351) 1 NC_009525.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2937351 ruvC 5213399 ruvC Mycobacterium tuberculosis H37Ra Holliday junction resolvase YP_001283956.1 2936785 R 419947 CDS YP_001283957.1 148662434 5213400 2937460..2937705 1 NC_009525.1 hypothetical protein 2937705 5213400 MRA_2623A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283957.1 2937460 D 419947 CDS YP_001283958.1 148662435 5213401 2937702..2938106 1 NC_009525.1 hypothetical protein 2938106 5213401 MRA_2624 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283958.1 2937702 D 419947 CDS YP_001283959.1 148662436 5213402 2938323..2938943 1 NC_009525.1 hypothetical protein 2938943 5213402 MRA_2625 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283959.1 2938323 D 419947 CDS YP_001283960.1 148662437 5213403 2938954..2939448 1 NC_009525.1 hypothetical protein 2939448 5213403 MRA_2626 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283960.1 2938954 D 419947 CDS YP_001283961.1 148662438 5213404 2939445..2939876 1 NC_009525.1 hypothetical protein 2939876 5213404 MRA_2627 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283961.1 2939445 D 419947 CDS YP_001283962.1 148662439 5213405 2939958..2940359 1 NC_009525.1 integral membrane protein 2940359 5213405 MRA_2628 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001283962.1 2939958 D 419947 CDS YP_001283963.1 148662440 5213406 2940356..2941927 1 NC_009525.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 2941927 speE 5213406 speE Mycobacterium tuberculosis H37Ra spermidine synthase YP_001283963.1 2940356 D 419947 CDS YP_001283964.1 148662441 5213407 2942038..2942325 1 NC_009525.1 hypothetical protein 2942325 5213407 MRA_2629A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283964.1 2942038 D 419947 CDS YP_001283965.1 148662442 5212046 2942312..2942752 1 NC_009525.1 hypothetical protein 2942752 5212046 MRA_2630 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283965.1 2942312 D 419947 CDS YP_001283966.1 148662443 5212047 complement(2942773..2943528) 1 NC_009525.1 hypothetical protein 2943528 5212047 MRA_2631 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283966.1 2942773 R 419947 CDS YP_001283967.1 148662444 5212048 complement(2943661..2944257) 1 NC_009525.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 2944257 5212048 MRA_2632 Mycobacterium tuberculosis H37Ra glutamine amidotransferase subunit PdxT YP_001283967.1 2943661 R 419947 CDS YP_001283968.1 148662445 5212049 complement(2944265..2945110) 1 NC_009525.1 acyl-CoA thioesterase 2945110 tesB2 5212049 tesB2 Mycobacterium tuberculosis H37Ra acyl-CoA thioesterase YP_001283968.1 2944265 R 419947 CDS YP_001283969.1 148662446 5212050 complement(2945139..2946038) 1 NC_009525.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 2946038 5212050 MRA_2634 Mycobacterium tuberculosis H37Ra pyridoxal biosynthesis lyase PdxS YP_001283969.1 2945139 R 419947 CDS YP_001283970.1 148662447 5212051 2946166..2946840 1 NC_009525.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2946840 pdxH 5212051 pdxH Mycobacterium tuberculosis H37Ra pyridoxamine 5'-phosphate oxidase YP_001283970.1 2946166 D 419947 CDS YP_001283971.1 148662448 5212052 2947014..2948756 1 NC_009525.1 PPE family protein 2948756 5212052 MRA_2636 Mycobacterium tuberculosis H37Ra PPE family protein YP_001283971.1 2947014 D 419947 CDS YP_001283972.1 148662449 5212053 complement(2948778..2949833) 1 NC_009525.1 hypothetical protein 2949833 5212053 MRA_2637 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283972.1 2948778 R 419947 CDS YP_001283973.1 148662450 5212054 complement(2949833..2950969) 1 NC_009525.1 alpha-mannosyltransferase PimA 2950969 pimA 5212054 pimA Mycobacterium tuberculosis H37Ra alpha-mannosyltransferase PimA YP_001283973.1 2949833 R 419947 CDS YP_001283974.1 148662451 5213260 complement(2950980..2951930) 1 NC_009525.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 2951930 5213260 MRA_2639 Mycobacterium tuberculosis H37Ra lipid A biosynthesis lauroyl acyltransferase YP_001283974.1 2950980 R 419947 CDS YP_001283975.1 148662452 5213261 complement(2951927..2952580) 1 NC_009525.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2952580 pgsA1 5213261 pgsA1 Mycobacterium tuberculosis H37Ra CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001283975.1 2951927 R 419947 CDS YP_001283976.1 148662453 5213262 complement(2952577..2953164) 1 NC_009525.1 hypothetical protein 2953164 5213262 MRA_2641 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283976.1 2952577 R 419947 CDS YP_001283977.1 148662454 5213263 complement(2953157..2955235) 1 NC_009525.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2955235 thrS 5213263 thrS Mycobacterium tuberculosis H37Ra threonyl-tRNA synthetase YP_001283977.1 2953157 R 419947 CDS YP_001283978.1 148662455 5213264 complement(2955568..2956953) 1 NC_009525.1 PE-PGRS family protein 2956953 5213264 MRA_2643 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283978.1 2955568 R 419947 CDS YP_001283979.1 148662456 5213265 2957298..2957798 1 NC_009525.1 hypothetical protein 2957798 5213265 MRA_2644 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283979.1 2957298 D 419947 CDS YP_001283980.1 148662457 5213266 complement(2957815..2958255) 1 NC_009525.1 transmembrane protein 2958255 5213266 MRA_2645 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283980.1 2957815 R 419947 CDS YP_001283981.1 148662458 5213267 2958402..2959079 1 NC_009525.1 hypothetical protein 2959079 5213267 MRA_2646 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283981.1 2958402 D 419947 CDS YP_001283982.1 148662459 5213268 complement(2959064..2959417) 1 NC_009525.1 hypothetical protein 2959417 5213268 MRA_2647 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283982.1 2959064 R 419947 CDS YP_001283983.1 148662460 5212923 complement(2959430..2959855) 1 NC_009525.1 transmembrane protein 2959855 5212923 MRA_2648 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001283983.1 2959430 R 419947 CDS YP_001283984.1 148662461 5212924 complement(2959852..2960526) 1 NC_009525.1 transcriptional regulatory protein 2960526 5212924 MRA_2649 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001283984.1 2959852 R 419947 CDS YP_001283985.1 148662462 5212925 2960604..2961425 1 NC_009525.1 methyltransferase 2961425 5212925 MRA_2650 Mycobacterium tuberculosis H37Ra methyltransferase YP_001283985.1 2960604 D 419947 CDS YP_001283986.1 148662463 5212926 2961561..2962454 1 NC_009525.1 hypothetical protein 2962454 5212926 MRA_2651 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283986.1 2961561 D 419947 CDS YP_001283987.1 148662464 5212927 complement(2962457..2963275) 1 NC_009525.1 hypothetical protein 2963275 5212927 MRA_2652 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283987.1 2962457 R 419947 CDS YP_001283988.1 148662465 5212928 complement(2963290..2964471) 1 NC_009525.1 alanine and leucine rich transmembrane protein 2964471 5212928 MRA_2653 Mycobacterium tuberculosis H37Ra alanine and leucine rich transmembrane protein YP_001283988.1 2963290 R 419947 CDS YP_001283989.1 148662466 5212929 complement(2964530..2964961) 1 NC_009525.1 hypothetical protein 2964961 5212929 MRA_2654 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283989.1 2964530 R 419947 CDS YP_001283990.1 148662467 5212930 complement(2965475..2966716) 1 NC_009525.1 hypothetical protein 2966716 5212930 MRA_2655 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283990.1 2965475 R 419947 CDS YP_001283991.1 148662468 5212931 2967026..2967388 1 NC_009525.1 hypothetical protein 2967388 5212931 MRA_2656 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283991.1 2967026 D 419947 CDS YP_001283992.1 148662469 5213073 2967735..2968859 1 NC_009525.1 hypothetical protein 2968859 5213073 MRA_2657 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283992.1 2967735 D 419947 CDS YP_001283993.1 148662470 5213074 2968861..2969400 1 NC_009525.1 hypothetical protein 2969400 5213074 MRA_2658 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283993.1 2968861 D 419947 CDS YP_001283994.1 148662471 5213075 2969540..2970838 1 NC_009525.1 hypothetical protein 2970838 5213075 MRA_2659 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283994.1 2969540 D 419947 CDS YP_001283995.1 148662472 5213076 complement(2970877..2971158) 1 NC_009525.1 hypothetical protein 2971158 5213076 MRA_2660 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283995.1 2970877 R 419947 CDS YP_001283996.1 148662473 5213077 complement(2971303..2971788) 1 NC_009525.1 hypothetical protein 2971788 5213077 MRA_2661 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283996.1 2971303 R 419947 CDS YP_001283997.1 148662474 5213078 complement(2971815..2972069) 1 NC_009525.1 hypothetical protein 2972069 5213078 MRA_2662 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283997.1 2971815 R 419947 CDS YP_001283998.1 148662475 5213079 complement(2972073..2974373) 1 NC_009525.1 PE-PGRS family protein 2974373 5213079 MRA_2663 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001283998.1 2972073 R 419947 CDS YP_001283999.1 148662476 5213080 2974438..2974680 1 NC_009525.1 hypothetical protein 2974680 5213080 MRA_2664 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001283999.1 2974438 D 419947 CDS YP_001284000.1 148662477 5213081 2974681..2975358 1 NC_009525.1 hypothetical protein 2975358 5213081 MRA_2665 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284000.1 2974681 D 419947 CDS YP_001284001.1 148662478 5213357 2975554..2976210 1 NC_009525.1 DedA family protein 2976210 dedA 5213357 dedA Mycobacterium tuberculosis H37Ra DedA family protein YP_001284001.1 2975554 D 419947 CDS YP_001284002.1 148662479 5213358 2976373..2976819 1 NC_009525.1 hypothetical protein 2976819 5213358 MRA_2667 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284002.1 2976373 D 419947 CDS YP_001284003.1 148662480 5213359 complement(2976994..2977326) 1 NC_009525.1 hypothetical protein 2977326 5213359 MRA_2668 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284003.1 2976994 R 419947 CDS YP_001284004.1 148662481 5213360 complement(2977446..2977805) 1 NC_009525.1 transcription regulator ArsR 2977805 5213360 MRA_2669 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001284004.1 2977446 R 419947 CDS YP_001284005.1 148662482 5213361 2977907..2978365 1 NC_009525.1 cadmium inducible protein CadI 2978365 cadI 5213361 cadI Mycobacterium tuberculosis H37Ra cadmium inducible protein CadI YP_001284005.1 2977907 D 419947 CDS YP_001284006.1 148662483 5213362 2978501..2978881 1 NC_009525.1 transcription regulator ArsR 2978881 5213362 MRA_2671 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001284006.1 2978501 D 419947 CDS YP_001284007.1 148662484 5213363 2978878..2980374 1 NC_009525.1 arsenical resistance protein/arsenate reductase 2980374 arsC 5213363 arsC Mycobacterium tuberculosis H37Ra arsenical resistance protein/arsenate reductase YP_001284007.1 2978878 D 419947 CDS YP_001284008.1 148662485 5213364 2980378..2980800 1 NC_009525.1 hypothetical protein 2980800 5213364 MRA_2673 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284008.1 2980378 D 419947 CDS YP_001284009.1 148662486 5213025 2982091..2982522 1 NC_009525.1 hypothetical protein 2982522 5213025 MRA_2674 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284009.1 2982091 D 419947 CDS YP_001284010.1 148662487 5214438 2982519..2983517 1 NC_009525.1 phage integrase 2983517 5214438 MRA_2675 Mycobacterium tuberculosis H37Ra phage integrase YP_001284010.1 2982519 D 419947 CDS YP_001284011.1 148662488 5214439 2983627..2983995 1 NC_009525.1 hypothetical protein 2983995 5214439 MRA_2676 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284011.1 2983627 D 419947 CDS YP_001284012.1 148662489 5214440 2984128..2984454 1 NC_009525.1 IS6110 hypothetical protein 2984454 5214440 MRA_2677 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001284012.1 2984128 D 419947 CDS YP_001284013.1 148662490 5214441 2984505..2985389 1 NC_009525.1 IS6110 transposase 2985389 5214441 MRA_2678 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001284013.1 2984505 D 419947 CDS YP_001284014.1 148662491 5214442 2985386..2985592 1 NC_009525.1 hypothetical protein 2985592 5214442 MRA_2679 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284014.1 2985386 D 419947 CDS YP_001284015.1 148662492 5214443 complement(2985763..2987202) 1 NC_009525.1 phiRv2 prophage protein 2987202 5214443 MRA_2680 Mycobacterium tuberculosis H37Ra phiRv2 prophage protein YP_001284015.1 2985763 R 419947 CDS YP_001284016.1 148662493 5214444 complement(2987210..2987743) 1 NC_009525.1 phage prohead protease 2987743 5214444 MRA_2681 Mycobacterium tuberculosis H37Ra phage prohead protease YP_001284016.1 2987210 R 419947 CDS YP_001284017.1 148662494 5214445 complement(2987896..2988522) 1 NC_009525.1 phiRv2 prophage protein 2988522 5214445 MRA_2682 Mycobacterium tuberculosis H37Ra phiRv2 prophage protein YP_001284017.1 2987896 R 419947 CDS YP_001284018.1 148662495 5214446 complement(2988554..2988877) 1 NC_009525.1 phiRv2 prophage protein 2988877 5214446 MRA_2683 Mycobacterium tuberculosis H37Ra phiRv2 prophage protein YP_001284018.1 2988554 R 419947 CDS YP_001284019.1 148662496 5214861 complement(2988957..2989202) 1 NC_009525.1 phiRv2 prophage protein 2989202 5214861 MRA_2684 Mycobacterium tuberculosis H37Ra phiRv2 prophage protein YP_001284019.1 2988957 R 419947 CDS YP_001284020.1 148662497 5214862 complement(2989199..2990626) 1 NC_009525.1 phiRv2 prophage protein 2990626 5214862 MRA_2685 Mycobacterium tuberculosis H37Ra phiRv2 prophage protein YP_001284020.1 2989199 R 419947 CDS YP_001284021.1 148662498 5214863 complement(2990628..2991020) 1 NC_009525.1 phiRv2 prophage protein 2991020 5214863 MRA_2686 Mycobacterium tuberculosis H37Ra phiRv2 prophage protein YP_001284021.1 2990628 R 419947 CDS YP_001284022.1 148662499 5214864 complement(2991017..2991277) 1 NC_009525.1 phiRv2 prophage protein 2991277 5214864 MRA_2687 Mycobacterium tuberculosis H37Ra phiRv2 prophage protein YP_001284022.1 2991017 R 419947 CDS YP_001284023.1 148662500 5214865 complement(2991294..2991656) 1 NC_009525.1 hypothetical protein 2991656 5214865 MRA_2688 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284023.1 2991294 R 419947 CDS YP_001284024.1 148662501 5214866 complement(2991659..2992786) 1 NC_009525.1 integrase 2992786 5214866 MRA_2689 Mycobacterium tuberculosis H37Ra integrase YP_001284024.1 2991659 R 419947 CDS YP_001284025.1 148662502 5214867 complement(2992931..2993398) 1 NC_009525.1 hypothetical protein 2993398 5214867 MRA_2690 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284025.1 2992931 R 419947 CDS YP_001284026.1 148662503 5214868 2993450..2993722 1 NC_009525.1 hypothetical protein 2993722 5214868 MRA_2690A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284026.1 2993450 D 419947 CDS YP_001284027.1 148662504 5214869 2993821..2994054 1 NC_009525.1 hypothetical protein 2994054 5214869 MRA_2691 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284027.1 2993821 D 419947 CDS YP_001284028.1 148662505 5213441 2994065..2994319 1 NC_009525.1 hypothetical protein 2994319 5213441 MRA_2692 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284028.1 2994065 D 419947 CDS YP_001284029.1 148662506 5213442 2994667..2994948 1 NC_009525.1 hypothetical protein 2994948 5213442 MRA_2693 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284029.1 2994667 D 419947 CDS YP_001284030.1 148662507 5213443 2995039..2995842 1 NC_009525.1 truncated IS1081 transposase 2995842 5213443 MRA_2694 Mycobacterium tuberculosis H37Ra truncated IS1081 transposase YP_001284030.1 2995039 D 419947 CDS YP_001284031.1 148662508 5213444 2995864..2996622 1 NC_009525.1 ATP-dependent protease ATP-binding subunit ClpC2 2996622 clpC2 5213444 clpC2 Mycobacterium tuberculosis H37Ra ATP-dependent protease ATP-binding subunit ClpC2 YP_001284031.1 2995864 D 419947 CDS YP_001284032.1 148662509 5213445 2996701..2997222 1 NC_009525.1 alanine and valine rich exported protein 2997222 5213445 MRA_2696 Mycobacterium tuberculosis H37Ra alanine and valine rich exported protein YP_001284032.1 2996701 D 419947 CDS YP_001284033.1 148662510 5213446 2997251..2997721 1 NC_009525.1 hypothetical protein 2997721 5213446 MRA_2697 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284033.1 2997251 D 419947 CDS YP_001284034.1 148662511 5213447 complement(2997699..2998808) 1 NC_009525.1 hypothetical protein 2998808 5213447 MRA_2698 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284034.1 2997699 R 419947 CDS YP_001284035.1 148662512 5213448 2998807..2999583 1 NC_009525.1 hypothetical protein 2999583 ribD 5213448 ribD Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284035.1 2998807 D 419947 CDS YP_001284036.1 148662513 5213449 2999650..3001236 1 NC_009525.1 proteinase 3001236 5213449 MRA_2700 Mycobacterium tuberculosis H37Ra proteinase YP_001284036.1 2999650 D 419947 CDS YP_001284037.1 148662514 5213572 3001259..3002560 1 NC_009525.1 integral membrane protein 3002560 5213572 MRA_2701 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284037.1 3001259 D 419947 CDS YP_001284038.1 148662515 5213573 3002674..3003084 1 NC_009525.1 hypothetical protein 3003084 5213573 MRA_2702 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284038.1 3002674 D 419947 CDS YP_001284039.1 148662516 5213574 complement(3003152..3003904) 1 NC_009525.1 hypothetical protein 3003904 5213574 MRA_2703 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284039.1 3003152 R 419947 CDS YP_001284040.1 148662517 5213575 complement(3003901..3004596) 1 NC_009525.1 hypothetical protein 3004596 5213575 MRA_2704 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284040.1 3003901 R 419947 CDS YP_001284041.1 148662518 5213576 complement(3004602..3005960) 1 NC_009525.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX; protoporphyrinogen oxidase 3005960 hemY 5213576 hemY Mycobacterium tuberculosis H37Ra protoporphyrinogen oxidase YP_001284041.1 3004602 R 419947 CDS YP_001284042.1 148662519 5213577 complement(3005957..3007030) 1 NC_009525.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 3007030 hemE 5213577 hemE Mycobacterium tuberculosis H37Ra uroporphyrinogen decarboxylase YP_001284042.1 3005957 R 419947 CDS YP_001284043.1 148662520 5213578 3007083..3007913 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3007913 echA15 5213578 echA15 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001284043.1 3007083 D 419947 CDS YP_001284044.1 148662521 5213579 3008073..3008705 1 NC_009525.1 hypothetical protein 3008705 5213579 MRA_2708 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284044.1 3008073 D 419947 CDS YP_001284045.1 148662522 5213580 3008707..3010023 1 NC_009525.1 ribonuclease D 3010023 5213580 MRA_2709 Mycobacterium tuberculosis H37Ra ribonuclease D YP_001284045.1 3008707 D 419947 CDS YP_001284046.1 148662523 5213834 complement(3010020..3011936) 1 NC_009525.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3011936 dxs1 5213834 dxs1 Mycobacterium tuberculosis H37Ra 1-deoxy-D-xylulose-5-phosphate synthase YP_001284046.1 3010020 R 419947 CDS YP_001284047.1 148662524 5213835 3012080..3012577 1 NC_009525.1 hypothetical protein 3012577 5213835 MRA_2711 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284047.1 3012080 D 419947 CDS YP_001284048.1 148662525 5213836 3012582..3013871 1 NC_009525.1 arsenic-transport integral membrane protein ArsA 3013871 arsA 5213836 arsA Mycobacterium tuberculosis H37Ra arsenic-transport integral membrane protein ArsA YP_001284048.1 3012582 D 419947 CDS YP_001284049.1 148662526 5213837 3013951..3015237 1 NC_009525.1 arsenic-transport integral membrane protein ArsB1 3015237 arsB1 5213837 arsB1 Mycobacterium tuberculosis H37Ra arsenic-transport integral membrane protein ArsB1 YP_001284049.1 3013951 D 419947 CDS YP_001284050.1 148662527 5213838 complement(3015248..3016006) 1 NC_009525.1 antibiotic ABC transporter permease 3016006 5213838 MRA_2714 Mycobacterium tuberculosis H37Ra antibiotic ABC transporter permease YP_001284050.1 3015248 R 419947 CDS YP_001284051.1 148662528 5213839 complement(3016003..3016716) 1 NC_009525.1 antibiotic ABC transporter permease 3016716 5213839 MRA_2715 Mycobacterium tuberculosis H37Ra antibiotic ABC transporter permease YP_001284051.1 3016003 R 419947 CDS YP_001284052.1 148662529 5213840 complement(3016713..3017618) 1 NC_009525.1 antibiotic ABC transporter ATP-binding protein 3017618 5213840 MRA_2716 Mycobacterium tuberculosis H37Ra antibiotic ABC transporter ATP-binding protein YP_001284052.1 3016713 R 419947 CDS YP_001284053.1 148662530 5213841 complement(3017813..3019030) 1 NC_009525.1 hypothetical protein 3019030 5213841 MRA_2717 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284053.1 3017813 R 419947 CDS YP_001284054.1 148662531 5213842 complement(3019204..3021177) 1 NC_009525.1 alanine,valine and leucine rich integral membrane protein 3021177 5213842 MRA_2718 Mycobacterium tuberculosis H37Ra alanine,valine and leucine rich integral membrane protein YP_001284054.1 3019204 R 419947 CDS YP_001284055.1 148662532 5212343 3021312..3021995 1 NC_009525.1 trk system potassium uptake protein CeoB 3021995 ceoB 5212343 ceoB Mycobacterium tuberculosis H37Ra trk system potassium uptake protein CeoB YP_001284055.1 3021312 D 419947 CDS YP_001284056.1 148662533 5212344 3021992..3022654 1 NC_009525.1 potassium uptake protein 3022654 ceoC 5212344 ceoC Mycobacterium tuberculosis H37Ra potassium uptake protein YP_001284056.1 3021992 D 419947 CDS YP_001284057.1 148662534 5212345 complement(3022665..3023336) 1 NC_009525.1 alanine and leucine rich integral membrane protein 3023336 5212345 MRA_2721 Mycobacterium tuberculosis H37Ra alanine and leucine rich integral membrane protein YP_001284057.1 3022665 R 419947 CDS YP_001284058.1 148662535 5212346 complement(3023367..3023735) 1 NC_009525.1 hypothetical protein 3023735 5212346 MRA_2722 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284058.1 3023367 R 419947 CDS YP_001284059.1 148662536 5212347 3023884..3024591 1 NC_009525.1 hypothetical protein 3024591 5212347 MRA_2723 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284059.1 3023884 D 419947 CDS YP_001284060.1 148662537 5212348 complement(3024797..3025576) 1 NC_009525.1 hypothetical protein 3025576 5212348 MRA_2724 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284060.1 3024797 R 419947 CDS YP_001284061.1 148662538 5212349 complement(3025651..3026115) 1 NC_009525.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3026115 dut 5212349 dut Mycobacterium tuberculosis H37Ra deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001284061.1 3025651 R 419947 CDS YP_001284062.1 148662539 5212350 3026141..3026626 1 NC_009525.1 alanine rich transmembrane protein 3026626 5212350 MRA_2726 Mycobacterium tuberculosis H37Ra alanine rich transmembrane protein YP_001284062.1 3026141 D 419947 CDS YP_001284063.1 148662540 5212351 complement(3026631..3026933) 1 NC_009525.1 hypothetical protein 3026933 5212351 MRA_2727 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284063.1 3026631 R 419947 CDS YP_001284064.1 148662541 5212593 3027171..3027821 1 NC_009525.1 alanine rich secreted protein 3027821 5212593 MRA_2728 Mycobacterium tuberculosis H37Ra alanine rich secreted protein YP_001284064.1 3027171 D 419947 CDS YP_001284065.1 148662542 5212594 complement(3027831..3028703) 1 NC_009525.1 extragenic suppressor protein SuhB 3028703 suhB 5212594 suhB Mycobacterium tuberculosis H37Ra extragenic suppressor protein SuhB YP_001284065.1 3027831 R 419947 CDS YP_001284066.1 148662543 5212595 3028826..3029623 1 NC_009525.1 polyphosphate glucokinase 3029623 ppgK 5212595 ppgK Mycobacterium tuberculosis H37Ra polyphosphate glucokinase YP_001284066.1 3028826 D 419947 CDS YP_001284067.1 148662544 5212596 3029803..3031389 1 NC_009525.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 3031389 sigA 5212596 sigA Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor YP_001284067.1 3029803 D 419947 CDS YP_001284068.1 148662545 5212597 3031426..3031854 1 NC_009525.1 hypothetical protein 3031854 5212597 MRA_2732 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284068.1 3031426 D 419947 CDS YP_001284069.1 148662546 5212598 complement(3031782..3032171) 1 NC_009525.1 hypothetical protein 3032171 5212598 MRA_2733 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284069.1 3031782 R 419947 CDS YP_001284070.1 148662547 5212599 complement(3032168..3032425) 1 NC_009525.1 hypothetical protein 3032425 5212599 MRA_2734 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284070.1 3032168 R 419947 CDS YP_001284071.1 148662548 5212600 3032541..3033515 1 NC_009525.1 alanine and leucine rich transmembrane protein 3033515 5212600 MRA_2735 Mycobacterium tuberculosis H37Ra alanine and leucine rich transmembrane protein YP_001284071.1 3032541 D 419947 CDS YP_001284072.1 148662549 5214601 complement(3033516..3033764) 1 NC_009525.1 hypothetical protein 3033764 5214601 MRA_2736 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284072.1 3033516 R 419947 CDS YP_001284073.1 148662550 5214602 3033807..3034253 1 NC_009525.1 transmembrane protein 3034253 5214602 MRA_2737 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284073.1 3033807 D 419947 CDS YP_001284074.1 148662551 5214603 3034429..3035400 1 NC_009525.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase; RNA polymerase sigma factor SigB 3035400 sigB 5214603 sigB Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigB YP_001284074.1 3034429 D 419947 CDS YP_001284075.1 148662552 5214604 3035533..3036225 1 NC_009525.1 iron-dependent repressor IdeR 3036225 ideR 5214604 ideR Mycobacterium tuberculosis H37Ra iron-dependent repressor IdeR YP_001284075.1 3035533 D 419947 CDS YP_001284076.1 148662553 5214605 complement(3036238..3037296) 1 NC_009525.1 hypothetical protein 3037296 5214605 MRA_2740 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284076.1 3036238 R 419947 CDS YP_001284077.1 148662554 5214606 3037409..3038815 1 NC_009525.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 3038815 sthA 5214606 sthA Mycobacterium tuberculosis H37Ra soluble pyridine nucleotide transhydrogenase YP_001284077.1 3037409 D 419947 CDS YP_001284078.1 148662555 5214607 3039033..3040007 1 NC_009525.1 hypothetical protein 3040007 5214607 MRA_2742 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284078.1 3039033 D 419947 CDS YP_001284079.1 148662556 5214608 3040066..3041091 1 NC_009525.1 hydrolase 3041091 5214608 MRA_2743 Mycobacterium tuberculosis H37Ra hydrolase YP_001284079.1 3040066 D 419947 CDS YP_001284080.1 148662557 5214609 3041140..3041826 1 NC_009525.1 hypothetical protein 3041826 5214609 MRA_2744 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284080.1 3041140 D 419947 CDS YP_001284081.1 148662558 5213035 complement(3041835..3042329) 1 NC_009525.1 hypothetical protein 3042329 5213035 MRA_2745 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284081.1 3041835 R 419947 CDS YP_001284082.1 148662559 5213036 complement(3042381..3042845) 1 NC_009525.1 transcriptional regulator NrdR 3042845 nrdR 5213036 nrdR Mycobacterium tuberculosis H37Ra transcriptional regulator NrdR YP_001284082.1 3042381 R 419947 CDS YP_001284083.1 148662560 5213037 complement(3043008..3043505) 1 NC_009525.1 hypothetical protein 3043505 5213037 MRA_2747 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284083.1 3043008 R 419947 CDS YP_001284084.1 148662561 5213038 3043813..3044466 1 NC_009525.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 3044466 lexA 5213038 lexA Mycobacterium tuberculosis H37Ra LexA repressor YP_001284084.1 3043813 D 419947 CDS YP_001284085.1 148662562 5213039 complement(3044488..3046587) 1 NC_009525.1 alanine and glycine rich transmembrane protein 3046587 5213039 MRA_2749 Mycobacterium tuberculosis H37Ra alanine and glycine rich transmembrane protein YP_001284085.1 3044488 R 419947 CDS YP_001284086.1 148662563 5213040 3046603..3046851 1 NC_009525.1 hypothetical protein 3046851 5213040 MRA_2749A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284086.1 3046603 D 419947 CDS YP_001284087.1 148662564 5213041 3046877..3048070 1 NC_009525.1 integral membrane protein 3048070 5213041 MRA_2750 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284087.1 3046877 D 419947 CDS YP_001284088.1 148662565 5213042 complement(3048099..3049259) 1 NC_009525.1 acyl-CoA dehydrogenase 3049259 fadE20 5213042 fadE20 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284088.1 3048099 R 419947 CDS YP_001284089.1 148662566 5214172 complement(3049395..3050882) 1 NC_009525.1 GTP-binding protein HflX 3050882 hflX 5214172 hflX Mycobacterium tuberculosis H37Ra GTP-binding protein HflX YP_001284089.1 3049395 R 419947 CDS YP_001284090.1 148662567 5214173 complement(3050899..3051768) 1 NC_009525.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 3051768 dapF 5214173 dapF Mycobacterium tuberculosis H37Ra diaminopimelate epimerase YP_001284090.1 3050899 R 419947 CDS YP_001284091.1 148662568 5214174 complement(3051793..3052737) 1 NC_009525.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 3052737 miaA 5214174 miaA Mycobacterium tuberculosis H37Ra tRNA delta(2)-isopentenylpyrophosphate transferase YP_001284091.1 3051793 R 419947 CDS YP_001284092.1 148662569 5214175 complement(3052734..3053429) 1 NC_009525.1 hypothetical protein 3053429 5214175 MRA_2755 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284092.1 3052734 R 419947 CDS YP_001284093.1 148662570 5214176 complement(3053538..3054443) 1 NC_009525.1 alanine,valine and leucine rich integral membrane protein 3054443 5214176 MRA_2756 Mycobacterium tuberculosis H37Ra alanine,valine and leucine rich integral membrane protein YP_001284093.1 3053538 R 419947 CDS YP_001284094.1 148662571 5214177 3054510..3054986 1 NC_009525.1 hypothetical protein 3054986 5214177 MRA_2756A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284094.1 3054510 D 419947 CDS YP_001284095.1 148662572 5214178 3054994..3056346 1 NC_009525.1 hypothetical protein 3056346 5214178 MRA_2757 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284095.1 3054994 D 419947 CDS YP_001284096.1 148662573 5214179 complement(3056343..3056957) 1 NC_009525.1 transmembrane protein 3056957 5214179 MRA_2758 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284096.1 3056343 R 419947 CDS YP_001284097.1 148662574 5214180 complement(3056954..3058492) 1 NC_009525.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 3058492 5214180 MRA_2759 Mycobacterium tuberculosis H37Ra (dimethylallyl)adenosine tRNA methylthiotransferase YP_001284097.1 3056954 R 419947 CDS YP_001284098.1 148662575 5213937 3058789..3059643 1 NC_009525.1 hypothetical protein 3059643 5213937 MRA_2760 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284098.1 3058789 D 419947 CDS YP_001284099.1 148662576 5213938 complement(3059528..3060520) 1 NC_009525.1 hypothetical protein 3060520 5213938 MRA_2761 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284099.1 3059528 R 419947 CDS YP_001284100.1 148662577 5213939 complement(3060530..3061054) 1 NC_009525.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3061054 recX 5213939 recX Mycobacterium tuberculosis H37Ra recombination regulator RecX YP_001284100.1 3060530 R 419947 CDS YP_001284101.1 148662578 5213940 complement(3061020..3063392) 1 NC_009525.1 these RecA proteins contain inteins; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; DNA recombination protein RecA 3063392 recA 5213940 recA Mycobacterium tuberculosis H37Ra DNA recombination protein RecA YP_001284101.1 3061020 R 419947 CDS YP_001284102.1 148662579 5213941 3063587..3063760 1 NC_009525.1 hypothetical protein 3063760 5213941 MRA_2764 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284102.1 3063587 D 419947 CDS YP_001284103.1 148662580 5213942 complement(3063774..3063980) 1 NC_009525.1 hypothetical protein 3063980 5213942 MRA_2765 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284103.1 3063774 R 419947 CDS YP_001284104.1 148662581 5213943 complement(3063991..3065157) 1 NC_009525.1 hypothetical protein 3065157 5213943 MRA_2766 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284104.1 3063991 R 419947 CDS YP_001284105.1 148662582 5213944 3065201..3065650 1 NC_009525.1 hypothetical protein 3065650 5213944 MRA_2766A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284105.1 3065201 D 419947 CDS YP_001284106.1 148662583 5213945 3065780..3067459 1 NC_009525.1 PE-PGRS family protein 3067459 5213945 MRA_2767 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284106.1 3065780 D 419947 CDS YP_001284107.1 148662584 5213721 complement(3067483..3068316) 1 NC_009525.1 hypothetical protein 3068316 5213721 MRA_2768 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284107.1 3067483 R 419947 CDS YP_001284108.1 148662585 5213722 complement(3068388..3069200) 1 NC_009525.1 alanine rich transmembrane protein 3069200 5213722 MRA_2769 Mycobacterium tuberculosis H37Ra alanine rich transmembrane protein YP_001284108.1 3068388 R 419947 CDS YP_001284109.1 148662586 5213723 complement(3069219..3070031) 1 NC_009525.1 hypothetical protein 3070031 5213723 MRA_2770 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284109.1 3069219 R 419947 CDS YP_001284110.1 148662587 5213724 complement(3070161..3070499) 1 NC_009525.1 transcriptional regulatory protein 3070499 5213724 MRA_2771 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001284110.1 3070161 R 419947 CDS YP_001284111.1 148662588 5213725 complement(3070570..3071199) 1 NC_009525.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3071199 pgsA3 5213725 pgsA3 Mycobacterium tuberculosis H37Ra CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001284111.1 3070570 R 419947 CDS YP_001284112.1 148662589 5213726 3071230..3071754 1 NC_009525.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase 3071754 5213726 MRA_2773 Mycobacterium tuberculosis H37Ra N-acetylglutamate synthase YP_001284112.1 3071230 D 419947 CDS YP_001284113.1 148662590 5213727 complement(3071823..3074474) 1 NC_009525.1 DNA translocase FtsK 3074474 ftsK 5213727 ftsK Mycobacterium tuberculosis H37Ra DNA translocase FtsK YP_001284113.1 3071823 R 419947 CDS YP_001284114.1 148662591 5213728 3074473..3074787 1 NC_009525.1 hypothetical protein 3074787 5213728 MRA_2774A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284114.1 3074473 D 419947 CDS YP_001284115.1 148662592 5213590 3074784..3075602 1 NC_009525.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 3075602 5213590 MRA_2775 Mycobacterium tuberculosis H37Ra 3-ketoacyl-ACP reductase YP_001284115.1 3074784 D 419947 CDS YP_001284116.1 148662593 5213591 3075606..3076496 1 NC_009525.1 hypothetical protein 3076496 5213591 MRA_2776 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284116.1 3075606 D 419947 CDS YP_001284117.1 148662594 5213592 complement(3076483..3078159) 1 NC_009525.1 hypothetical protein 3078159 5213592 MRA_2777 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284117.1 3076483 R 419947 CDS YP_001284118.1 148662595 5213593 complement(3078190..3079092) 1 NC_009525.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3079092 dapA 5213593 dapA Mycobacterium tuberculosis H37Ra dihydrodipicolinate synthase YP_001284118.1 3078190 R 419947 CDS YP_001284119.1 148662596 5213594 complement(3079161..3079913) 1 NC_009525.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 3079913 thyX 5213594 thyX Mycobacterium tuberculosis H37Ra FAD-dependent thymidylate synthase YP_001284119.1 3079161 R 419947 CDS YP_001284120.1 148662597 5213595 complement(3080157..3080432) 1 NC_009525.1 type I restriction/modification system specificity determinant HsdS' 3080432 hsdS' 5213595 hsdS' Mycobacterium tuberculosis H37Ra type I restriction/modification system specificity determinant HsdS' YP_001284120.1 3080157 R 419947 CDS YP_001284121.1 148662598 5213596 complement(3080429..3082051) 1 NC_009525.1 type I restriction/modification system DNA methylase HsdM 3082051 hsdM 5213596 hsdM Mycobacterium tuberculosis H37Ra type I restriction/modification system DNA methylase HsdM YP_001284121.1 3080429 R 419947 CDS YP_001284122.1 148662599 5213597 complement(3082138..3082554) 1 NC_009525.1 hypothetical protein 3082554 5213597 MRA_2782 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284122.1 3082138 R 419947 CDS YP_001284123.1 148662600 5213598 complement(3082551..3082817) 1 NC_009525.1 hypothetical protein 3082817 5213598 MRA_2783 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284123.1 3082551 R 419947 CDS YP_001284124.1 148662601 5212313 complement(3082843..3083238) 1 NC_009525.1 hypothetical protein 3083238 5212313 MRA_2784 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284124.1 3082843 R 419947 CDS YP_001284125.1 148662602 5212314 complement(3083235..3083504) 1 NC_009525.1 hypothetical protein 3083504 5212314 MRA_2785 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284125.1 3083235 R 419947 CDS YP_001284126.1 148662603 5212315 complement(3083514..3084608) 1 NC_009525.1 type I restriction system specificity protein 3084608 hsdS 5212315 hsdS Mycobacterium tuberculosis H37Ra type I restriction system specificity protein YP_001284126.1 3083514 R 419947 CDS YP_001284127.1 148662604 5212316 complement(3084605..3085024) 1 NC_009525.1 hypothetical protein 3085024 5212316 MRA_2787 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284127.1 3084605 R 419947 CDS YP_001284128.1 148662605 5212317 complement(3085098..3085577) 1 NC_009525.1 dihydrofolate reductase 3085577 dfrA 5212317 dfrA Mycobacterium tuberculosis H37Ra dihydrofolate reductase YP_001284128.1 3085098 R 419947 CDS YP_001284129.1 148662606 5212318 complement(3085648..3086439) 1 NC_009525.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3086439 thyA 5212318 thyA Mycobacterium tuberculosis H37Ra thymidylate synthase YP_001284129.1 3085648 R 419947 CDS YP_001284130.1 148662607 5212319 3086604..3087341 1 NC_009525.1 carboxymethylenebutenolidase 3087341 5212319 MRA_2790 Mycobacterium tuberculosis H37Ra carboxymethylenebutenolidase YP_001284130.1 3086604 D 419947 CDS YP_001284131.1 148662608 5212320 complement(3087556..3088338) 1 NC_009525.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 3088338 fabG 5212320 fabG Mycobacterium tuberculosis H37Ra 3-ketoacyl-ACP reductase YP_001284131.1 3087556 R 419947 CDS YP_001284132.1 148662609 5212201 complement(3088335..3088688) 1 NC_009525.1 hypothetical protein 3088688 5212201 MRA_2792 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284132.1 3088335 R 419947 CDS YP_001284133.1 148662610 5212202 complement(3088862..3090046) 1 NC_009525.1 PPE family protein 3090046 5212202 MRA_2793 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284133.1 3088862 R 419947 CDS YP_001284134.1 148662611 5212203 complement(3090126..3090953) 1 NC_009525.1 PE family protein 3090953 5212203 MRA_2794 Mycobacterium tuberculosis H37Ra PE family protein YP_001284134.1 3090126 R 419947 CDS YP_001284135.1 148662612 5212204 complement(3091277..3092425) 1 NC_009525.1 PPE family protein 3092425 5212204 MRA_2795 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284135.1 3091277 R 419947 CDS YP_001284136.1 148662613 5212205 complement(3092549..3093001) 1 NC_009525.1 hypothetical protein 3093001 5212205 MRA_2796 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284136.1 3092549 R 419947 CDS YP_001284137.1 148662614 5212206 complement(3093087..3093560) 1 NC_009525.1 transmembrane protein 3093560 5212206 MRA_2797 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284137.1 3093087 R 419947 CDS YP_001284138.1 148662615 5212207 complement(3093572..3094309) 1 NC_009525.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 3094309 dapB 5212207 dapB Mycobacterium tuberculosis H37Ra dihydrodipicolinate reductase YP_001284138.1 3093572 R 419947 CDS YP_001284139.1 148662616 5212208 complement(3094320..3094724) 1 NC_009525.1 hypothetical protein 3094724 5212208 MRA_2798A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284139.1 3094320 R 419947 CDS YP_001284140.1 148662617 5212209 3094877..3095338 1 NC_009525.1 hypothetical protein 3095338 5212209 MRA_2799 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284140.1 3094877 D 419947 CDS YP_001284141.1 148662618 5215238 complement(3095342..3096271) 1 NC_009525.1 oxidoreductase 3096271 5215238 MRA_2800 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284141.1 3095342 R 419947 CDS YP_001284142.1 148662619 5215239 complement(3096453..3097523) 1 NC_009525.1 hypothetical protein 3097523 5215239 MRA_2801 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284142.1 3096453 R 419947 CDS YP_001284143.1 148662620 5215240 complement(3097681..3098151) 1 NC_009525.1 hypothetical protein 3098151 5215240 MRA_2802 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284143.1 3097681 R 419947 CDS YP_001284144.1 148662621 5215241 complement(3098183..3098722) 1 NC_009525.1 transcription regulator AsnC 3098722 5215241 MRA_2803 Mycobacterium tuberculosis H37Ra transcription regulator AsnC YP_001284144.1 3098183 R 419947 CDS YP_001284145.1 148662622 5215242 3098788..3099903 1 NC_009525.1 alanine dehydrogenase 3099903 ald 5215242 ald Mycobacterium tuberculosis H37Ra alanine dehydrogenase YP_001284145.1 3098788 D 419947 CDS YP_001284146.1 148662623 5215243 complement(3099918..3100952) 1 NC_009525.1 2-nitropropane dioxygenase 3100952 5215243 MRA_2805 Mycobacterium tuberculosis H37Ra 2-nitropropane dioxygenase YP_001284146.1 3099918 R 419947 CDS YP_001284147.1 148662624 5215244 complement(3101013..3102329) 1 NC_009525.1 zinc protease PepR 3102329 pepR 5215244 pepR Mycobacterium tuberculosis H37Ra zinc protease PepR YP_001284147.1 3101013 R 419947 CDS YP_001284148.1 148662625 5215245 complement(3102307..3104565) 1 NC_009525.1 polynucleotide phosphorylase 3104565 gpsI 5215245 gpsI Mycobacterium tuberculosis H37Ra polynucleotide phosphorylase YP_001284148.1 3102307 R 419947 CDS YP_001284149.1 148662626 5212678 complement(3104919..3105434) 1 NC_009525.1 lipoprotein LppU 3105434 lppU 5212678 lppU Mycobacterium tuberculosis H37Ra lipoprotein LppU YP_001284149.1 3104919 R 419947 CDS YP_001284150.1 148662627 5212679 complement(3105447..3105716) 1 NC_009525.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3105716 rpsO 5212679 rpsO Mycobacterium tuberculosis H37Ra 30S ribosomal protein S15 YP_001284150.1 3105447 R 419947 CDS YP_001284151.1 148662628 5212680 complement(3105873..3106868) 1 NC_009525.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 3106868 ribF 5212680 ribF Mycobacterium tuberculosis H37Ra bifunctional riboflavin kinase/FMN adenylyltransferase YP_001284151.1 3105873 R 419947 CDS YP_001284152.1 148662629 5212681 3107079..3108842 1 NC_009525.1 hypothetical protein 3108842 5212681 MRA_2811 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284152.1 3107079 D 419947 CDS YP_001284153.1 148662630 5212682 3108927..3109613 1 NC_009525.1 iron repressor protein 3109613 sirR 5212682 sirR Mycobacterium tuberculosis H37Ra iron repressor protein YP_001284153.1 3108927 D 419947 CDS YP_001284154.1 148662631 5212683 complement(3109674..3110906) 1 NC_009525.1 acyl-CoA dehydrogenase 3110906 fadE21 5212683 fadE21 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284154.1 3109674 R 419947 CDS YP_001284155.1 148662632 5212684 complement(3110932..3112137) 1 NC_009525.1 lipid-transfer protein 3112137 ltp1 5212684 ltp1 Mycobacterium tuberculosis H37Ra lipid-transfer protein YP_001284155.1 3110932 R 419947 CDS YP_001284156.1 148662633 5212685 complement(3112170..3113549) 1 NC_009525.1 IS1602 transposase 3113549 5212685 MRA_2815 Mycobacterium tuberculosis H37Ra IS1602 transposase YP_001284156.1 3112170 R 419947 CDS YP_001284157.1 148662634 5212686 complement(3113549..3114130) 1 NC_009525.1 IS1602 resolvase 3114130 5212686 MRA_2816 Mycobacterium tuberculosis H37Ra IS1602 resolvase YP_001284157.1 3113549 R 419947 CDS YP_001284158.1 148662635 5214677 complement(3114332..3115228) 1 NC_009525.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3115228 truB 5214677 truB Mycobacterium tuberculosis H37Ra tRNA pseudouridine synthase B YP_001284158.1 3114332 R 419947 CDS YP_001284159.1 148662636 5214678 complement(3115225..3115908) 1 NC_009525.1 hypothetical protein 3115908 5214678 MRA_2818 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284159.1 3115225 R 419947 CDS YP_001284160.1 148662637 5214679 complement(3115905..3116879) 1 NC_009525.1 hypothetical protein 3116879 5214679 MRA_2819 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284160.1 3115905 R 419947 CDS YP_001284161.1 148662638 5214680 complement(3117024..3117587) 1 NC_009525.1 lipoprotein LppV 3117587 lppV 5214680 lppV Mycobacterium tuberculosis H37Ra lipoprotein LppV YP_001284161.1 3117024 R 419947 CDS YP_001284162.1 148662639 5214681 complement(3117587..3119275) 1 NC_009525.1 hypothetical protein 3119275 5214681 MRA_2821 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284162.1 3117587 R 419947 CDS YP_001284163.1 148662640 5214682 complement(3119279..3119605) 1 NC_009525.1 hypothetical protein 3119605 5214682 MRA_2822 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284163.1 3119279 R 419947 CDS YP_001284164.1 148662641 5214683 3119736..3120365 1 NC_009525.1 hypothetical protein 3120365 5214683 MRA_2823 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284164.1 3119736 D 419947 CDS YP_001284165.1 148662642 5214684 3120384..3122033 1 NC_009525.1 diester hydrolase 3122033 5214684 MRA_2824 Mycobacterium tuberculosis H37Ra diester hydrolase YP_001284165.1 3120384 D 419947 CDS YP_001284166.1 148662643 5214685 complement(3122135..3122491) 1 NC_009525.1 hypothetical protein 3122491 5214685 MRA_2825 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284166.1 3122135 R 419947 CDS YP_001284167.1 148662644 5212427 complement(3122748..3123791) 1 NC_009525.1 hypothetical protein 3123791 5212427 MRA_2826 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284167.1 3122748 R 419947 CDS YP_001284168.1 148662645 5212428 3123790..3124257 1 NC_009525.1 hypothetical protein 3124257 5212428 MRA_2827 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284168.1 3123790 D 419947 CDS YP_001284169.1 148662646 5212429 complement(3124433..3125062) 1 NC_009525.1 hypothetical protein 3125062 5212429 MRA_2828 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284169.1 3124433 R 419947 CDS YP_001284170.1 148662647 5212430 3124835..3125239 1 NC_009525.1 hypothetical protein 3125239 5212430 MRA_2829 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284170.1 3124835 D 419947 CDS YP_001284171.1 148662648 5212431 3125236..3125427 1 NC_009525.1 hypothetical protein 3125427 5212431 MRA_2830 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284171.1 3125236 D 419947 CDS YP_001284172.1 148662649 5212432 3125626..3126780 1 NC_009525.1 hypothetical protein 3126780 5212432 MRA_2831 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284172.1 3125626 D 419947 CDS YP_001284173.1 148662650 5212433 3127014..3127271 1 NC_009525.1 hypothetical protein 3127271 5212433 MRA_2832 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284173.1 3127014 D 419947 CDS YP_001284174.1 148662651 5212434 3127376..3127687 1 NC_009525.1 hypothetical protein 3127687 5212434 MRA_2833 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284174.1 3127376 D 419947 CDS YP_001284175.1 148662652 5212435 complement(3127709..3128026) 1 NC_009525.1 transposase 3128026 5212435 MRA_2834 Mycobacterium tuberculosis H37Ra transposase YP_001284175.1 3127709 R 419947 CDS YP_001284176.1 148662653 5213991 3128107..3128715 1 NC_009525.1 hypothetical protein 3128715 5213991 MRA_2835 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284176.1 3128107 D 419947 CDS YP_001284177.1 148662654 5213992 3128786..3130195 1 NC_009525.1 transposase 3130195 5213992 MRA_2836 Mycobacterium tuberculosis H37Ra transposase YP_001284177.1 3128786 D 419947 CDS YP_001284178.1 148662655 5213993 3130192..3131004 1 NC_009525.1 hypothetical protein 3131004 5213993 MRA_2837 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284178.1 3130192 D 419947 CDS YP_001284179.1 148662656 5213994 complement(3132534..3133418) 1 NC_009525.1 IS6110 transposase 3133418 5213994 MRA_2838 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001284179.1 3132534 R 419947 CDS YP_001284180.1 148662657 5213995 complement(3133469..3133795) 1 NC_009525.1 IS6110 hypothetical protein 3133795 5213995 MRA_2839 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001284180.1 3133469 R 419947 CDS YP_001284181.1 148662658 5213996 complement(3135616..3135957) 1 NC_009525.1 hypothetical protein 3135957 5213996 MRA_2840 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284181.1 3135616 R 419947 CDS YP_001284182.1 148662659 5213997 complement(3135958..3136974) 1 NC_009525.1 hypothetical protein 3136974 5213997 MRA_2841 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284182.1 3135958 R 419947 CDS YP_001284183.1 148662660 5213998 complement(3136987..3138135) 1 NC_009525.1 hypothetical protein 3138135 5213998 MRA_2842 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284183.1 3136987 R 419947 CDS YP_001284184.1 148662661 5213999 complement(3138231..3139358) 1 NC_009525.1 hypothetical protein 3139358 5213999 MRA_2843 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284184.1 3138231 R 419947 CDS YP_001284185.1 148662662 5215014 complement(3139355..3140263) 1 NC_009525.1 hypothetical protein 3140263 5215014 MRA_2844 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284185.1 3139355 R 419947 CDS YP_001284186.1 148662663 5215015 complement(3140244..3140954) 1 NC_009525.1 hypothetical protein 3140954 5215015 MRA_2845 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284186.1 3140244 R 419947 CDS YP_001284187.1 148662664 5215016 complement(3140964..3141338) 1 NC_009525.1 hypothetical protein 3141338 5215016 MRA_2846 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284187.1 3140964 R 419947 CDS YP_001284188.1 148662665 5215017 complement(3141335..3143764) 1 NC_009525.1 hypothetical protein 3143764 5215017 MRA_2847 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284188.1 3141335 R 419947 CDS YP_001284189.1 148662666 5215018 complement(3143761..3144705) 1 NC_009525.1 hypothetical protein 3144705 5215018 MRA_2848 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284189.1 3143761 R 419947 CDS YP_001284190.1 148662667 5215019 complement(3144883..3145530) 1 NC_009525.1 hypothetical protein 3145530 5215019 MRA_2849 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284190.1 3144883 R 419947 CDS YP_001284191.1 148662668 5215020 complement(3145701..3146585) 1 NC_009525.1 hypothetical protein 3146585 5215020 MRA_2850 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284191.1 3145701 R 419947 CDS YP_001284192.1 148662669 5215021 complement(3146588..3147475) 1 NC_009525.1 hypothetical protein 3147475 5215021 MRA_2851 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284192.1 3146588 R 419947 CDS YP_001284193.1 148662670 5215022 complement(3147780..3148325) 1 NC_009525.1 hypothetical protein 3148325 5215022 MRA_2852 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284193.1 3147780 R 419947 CDS YP_001284194.1 148662671 5215023 complement(3148322..3149047) 1 NC_009525.1 hypothetical protein 3149047 5215023 MRA_2853 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284194.1 3148322 R 419947 CDS YP_001284195.1 148662672 5215024 3149263..3150012 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3150012 echA16 5215024 echA16 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001284195.1 3149263 D 419947 CDS YP_001284196.1 148662673 5215025 complement(3150091..3151173) 1 NC_009525.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC 3151173 ugpC 5215025 ugpC Mycobacterium tuberculosis H37Ra sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC YP_001284196.1 3150091 R 419947 CDS YP_001284197.1 148662674 5215026 complement(3151166..3152476) 1 NC_009525.1 sn-glycerol-3-phosphate ABC transporter substrate-binding protein UspB 3152476 ugpB 5215026 ugpB Mycobacterium tuberculosis H37Ra sn-glycerol-3-phosphate ABC transporter substrate-binding protein UspB YP_001284197.1 3151166 R 419947 CDS YP_001284198.1 148662675 5215027 complement(3152479..3153306) 1 NC_009525.1 sn-glycerol-3-phosphate ABC transporter permease UgpE 3153306 ugpE 5215027 ugpE Mycobacterium tuberculosis H37Ra sn-glycerol-3-phosphate ABC transporter permease UgpE YP_001284198.1 3152479 R 419947 CDS YP_001284199.1 148662676 5215028 complement(3153303..3154214) 1 NC_009525.1 sn-glycerol-3-phosphate ABC transporter permease UgpA 3154214 ugpA 5215028 ugpA Mycobacterium tuberculosis H37Ra sn-glycerol-3-phosphate ABC transporter permease UgpA YP_001284199.1 3153303 R 419947 CDS YP_001284200.1 148662677 5215029 complement(3154301..3155620) 1 NC_009525.1 DNA-damage-inducible protein F 3155620 dinF 5215029 dinF Mycobacterium tuberculosis H37Ra DNA-damage-inducible protein F YP_001284200.1 3154301 R 419947 CDS YP_001284201.1 148662678 5215030 complement(3155627..3156637) 1 NC_009525.1 hypothetical protein 3156637 5215030 MRA_2860 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284201.1 3155627 R 419947 CDS YP_001284202.1 148662679 5213675 complement(3156612..3157163) 1 NC_009525.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3157163 rbfA 5213675 rbfA Mycobacterium tuberculosis H37Ra ribosome-binding factor A YP_001284202.1 3156612 R 419947 CDS YP_001284203.1 148662680 5213676 complement(3157163..3159865) 1 NC_009525.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3159865 infB 5213676 infB Mycobacterium tuberculosis H37Ra translation initiation factor IF-2 YP_001284203.1 3157163 R 419947 CDS YP_001284204.1 148662681 5213677 complement(3159951..3160250) 1 NC_009525.1 hypothetical protein 3160250 5213677 MRA_2863 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284204.1 3159951 R 419947 CDS YP_001284205.1 148662682 5213678 complement(3160377..3161420) 1 NC_009525.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3161420 nusA 5213678 nusA Mycobacterium tuberculosis H37Ra transcription elongation factor NusA YP_001284205.1 3160377 R 419947 CDS YP_001284206.1 148662683 5213679 complement(3161417..3161968) 1 NC_009525.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3161968 5213679 MRA_2865 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284206.1 3161417 R 419947 CDS YP_001284207.1 148662684 5213680 3162163..3162708 1 NC_009525.1 alanine rich transmembrane protein 3162708 5213680 MRA_2866 Mycobacterium tuberculosis H37Ra alanine rich transmembrane protein YP_001284207.1 3162163 D 419947 CDS YP_001284208.1 148662685 5213681 3162705..3163193 1 NC_009525.1 hypothetical protein 3163193 5213681 MRA_2867 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284208.1 3162705 D 419947 CDS YP_001284209.1 148662686 5213682 complement(3163194..3164942) 1 NC_009525.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 3164942 proS 5213682 proS Mycobacterium tuberculosis H37Ra prolyl-tRNA synthetase YP_001284209.1 3163194 R 419947 CDS YP_001284210.1 148662687 5213683 complement(3165031..3166623) 1 NC_009525.1 efflux protein 3166623 efpA 5213683 efpA Mycobacterium tuberculosis H37Ra efflux protein YP_001284210.1 3165031 R 419947 CDS YP_001284211.1 148662688 5212402 complement(3166646..3167863) 1 NC_009525.1 uroporphyrinogen III methyltransferase 3167863 cysG 5212402 cysG Mycobacterium tuberculosis H37Ra uroporphyrinogen III methyltransferase YP_001284211.1 3166646 R 419947 CDS YP_001284212.1 148662689 5212403 complement(3168140..3169513) 1 NC_009525.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 3169513 cobB 5212403 cobB Mycobacterium tuberculosis H37Ra cobyrinic acid a,c-diamide synthase YP_001284212.1 3168140 R 419947 CDS YP_001284213.1 148662690 5212404 complement(3169513..3170136) 1 NC_009525.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 3170136 cobO 5212404 cobO Mycobacterium tuberculosis H37Ra cob(I)yrinic acid a,c-diamide adenosyltransferase YP_001284213.1 3169513 R 419947 CDS YP_001284214.1 148662691 5212405 complement(3170157..3172046) 1 NC_009525.1 magnesium chelatase 3172046 5212405 MRA_2873 Mycobacterium tuberculosis H37Ra magnesium chelatase YP_001284214.1 3170157 R 419947 CDS YP_001284215.1 148662692 5212406 complement(3172043..3172513) 1 NC_009525.1 hypothetical protein 3172513 5212406 MRA_2874 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284215.1 3172043 R 419947 CDS YP_001284216.1 148662693 5212407 complement(3172572..3174053) 1 NC_009525.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 3174053 mqo 5212407 mqo Mycobacterium tuberculosis H37Ra malate:quinone oxidoreductase YP_001284216.1 3172572 R 419947 CDS YP_001284217.1 148662694 5212408 3174263..3176107 1 NC_009525.1 PE-PGRS family protein 3176107 5212408 MRA_2876 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284217.1 3174263 D 419947 CDS YP_001284218.1 148662695 5212409 3176144..3177184 1 NC_009525.1 hypothetical protein 3177184 5212409 MRA_2877 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284218.1 3176144 D 419947 CDS YP_001284219.1 148662696 5212374 3177197..3178576 1 NC_009525.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; mycothione reductase 3178576 mtr 5212374 mtr Mycobacterium tuberculosis H37Ra mycothione reductase YP_001284219.1 3177197 D 419947 CDS YP_001284220.1 148662697 5212375 3178676..3179794 1 NC_009525.1 HoxN/HupN/NixA family nickel transporter 3179794 nicT 5212375 nicT Mycobacterium tuberculosis H37Ra HoxN/HupN/NixA family nickel transporter YP_001284220.1 3178676 D 419947 CDS YP_001284221.1 148662698 5212376 3179860..3180192 1 NC_009525.1 hypothetical protein 3180192 5212376 MRA_2880 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284221.1 3179860 D 419947 CDS YP_001284222.1 148662699 5212377 3180204..3180419 1 NC_009525.1 hypothetical protein 3180419 5212377 MRA_2881 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284222.1 3180204 D 419947 CDS YP_001284223.1 148662700 5212378 complement(3180575..3181351) 1 NC_009525.1 short chain dehydrogenase 3181351 5212378 MRA_2882 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284223.1 3180575 R 419947 CDS YP_001284224.1 148662701 5212379 complement(3181348..3182715) 1 NC_009525.1 aldehyde dehydrogenase 3182715 aldC 5212379 aldC Mycobacterium tuberculosis H37Ra aldehyde dehydrogenase YP_001284224.1 3181348 R 419947 CDS YP_001284225.1 148662702 5212380 complement(3182712..3183638) 1 NC_009525.1 amidotransferase 3183638 5212380 MRA_2884 Mycobacterium tuberculosis H37Ra amidotransferase YP_001284225.1 3182712 R 419947 CDS YP_001284226.1 148662703 5212381 complement(3183619..3184992) 1 NC_009525.1 glutamine synthetase 3184992 glnA4 5212381 glnA4 Mycobacterium tuberculosis H37Ra glutamine synthetase YP_001284226.1 3183619 R 419947 CDS YP_001284227.1 148662704 5212382 complement(3185152..3186009) 1 NC_009525.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase 3186009 mapB 5212382 mapB Mycobacterium tuberculosis H37Ra methionine aminopeptidase YP_001284227.1 3185152 R 419947 CDS YP_001284228.1 148662705 5212017 complement(3186051..3186635) 1 NC_009525.1 hypothetical protein 3186635 5212017 MRA_2887 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284228.1 3186051 R 419947 CDS YP_001284229.1 148662706 5212018 3186984..3187364 1 NC_009525.1 hypothetical protein 3187364 5212018 MRA_2888 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284229.1 3186984 D 419947 CDS YP_001284230.1 148662707 5212019 complement(3187446..3189257) 1 NC_009525.1 penicillin-binding lipoprotein 3189257 5212019 MRA_2889 Mycobacterium tuberculosis H37Ra penicillin-binding lipoprotein YP_001284230.1 3187446 R 419947 CDS YP_001284231.1 148662708 5212020 3189529..3189810 1 NC_009525.1 hypothetical protein 3189810 5212020 MRA_2890 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284231.1 3189529 D 419947 CDS YP_001284232.1 148662709 5212021 3189814..3190077 1 NC_009525.1 hypothetical protein 3190077 5212021 MRA_2891 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284232.1 3189814 D 419947 CDS YP_001284233.1 148662710 5212022 complement(3190450..3191304) 1 NC_009525.1 hypothetical protein 3191304 5212022 MRA_2892 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284233.1 3190450 R 419947 CDS YP_001284234.1 148662711 5212023 complement(3191360..3192523) 1 NC_009525.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3192523 ispG 5212023 ispG Mycobacterium tuberculosis H37Ra 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001284234.1 3191360 R 419947 CDS YP_001284235.1 148662712 5212024 complement(3192540..3193754) 1 NC_009525.1 transmembrane protein 3193754 5212024 MRA_2894 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284235.1 3192540 R 419947 CDS YP_001284236.1 148662713 5212025 complement(3193762..3195003) 1 NC_009525.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3195003 dxr 5212025 dxr Mycobacterium tuberculosis H37Ra 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001284236.1 3193762 R 419947 CDS YP_001284237.1 148662714 5213116 3195130..3195387 1 NC_009525.1 hypothetical protein 3195387 5213116 MRA_2895A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284237.1 3195130 D 419947 CDS YP_001284238.1 148662715 5213117 3195374..3195817 1 NC_009525.1 hypothetical protein 3195817 5213117 MRA_2896 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284238.1 3195374 D 419947 CDS YP_001284239.1 148662716 5213118 3195897..3196559 1 NC_009525.1 cell surface lipoprotein Mpt83 3196559 mpt83 5213118 mpt83 Mycobacterium tuberculosis H37Ra cell surface lipoprotein Mpt83 YP_001284239.1 3195897 D 419947 CDS YP_001284240.1 148662717 5213119 3196655..3196846 1 NC_009525.1 hypothetical protein 3196846 5213119 MRA_2898 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284240.1 3196655 D 419947 CDS YP_001284241.1 148662718 5213120 3196839..3198926 1 NC_009525.1 integral membrane c-type cytochrome biogenesis protein DipZ 3198926 dipZ 5213120 dipZ Mycobacterium tuberculosis H37Ra integral membrane c-type cytochrome biogenesis protein DipZ YP_001284241.1 3196839 D 419947 CDS YP_001284242.1 148662719 5213121 3199022..3199603 1 NC_009525.1 antigen Mpt70 3199603 mpt70 5213121 mpt70 Mycobacterium tuberculosis H37Ra antigen Mpt70 YP_001284242.1 3199022 D 419947 CDS YP_001284243.1 148662720 5213122 3199655..3199969 1 NC_009525.1 transmembrane protein 3199969 5213122 MRA_2901 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284243.1 3199655 D 419947 CDS YP_001284244.1 148662721 5213123 complement(3200000..3200863) 1 NC_009525.1 mercury resistance transport protein 3200863 5213123 MRA_2902 Mycobacterium tuberculosis H37Ra mercury resistance transport protein YP_001284244.1 3200000 R 419947 CDS YP_001284245.1 148662722 5213124 complement(3200868..3201389) 1 NC_009525.1 soluble secreted antigen Mpt53 precursor 3201389 mpt53 5213124 mpt53 Mycobacterium tuberculosis H37Ra soluble secreted antigen Mpt53 precursor YP_001284245.1 3200868 R 419947 CDS YP_001284246.1 148662723 5213051 complement(3201575..3202162) 1 NC_009525.1 hypothetical protein 3202162 5213051 MRA_2904 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284246.1 3201575 R 419947 CDS YP_001284247.1 148662724 5213052 complement(3201843..3202670) 1 NC_009525.1 hypothetical protein 3202670 5213052 MRA_2905 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284247.1 3201843 R 419947 CDS YP_001284248.1 148662725 5213053 complement(3202693..3203613) 1 NC_009525.1 phosphatidate cytidylyltransferase 3203613 cdsA 5213053 cdsA Mycobacterium tuberculosis H37Ra phosphatidate cytidylyltransferase YP_001284248.1 3202693 R 419947 CDS YP_001284249.1 148662726 5213054 complement(3203636..3204193) 1 NC_009525.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 3204193 frr 5213054 frr Mycobacterium tuberculosis H37Ra ribosome recycling factor YP_001284249.1 3203636 R 419947 CDS YP_001284250.1 148662727 5213055 complement(3204365..3205150) 1 NC_009525.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 3205150 pyrH 5213055 pyrH Mycobacterium tuberculosis H37Ra uridylate kinase YP_001284250.1 3204365 R 419947 CDS YP_001284251.1 148662728 5213056 3205385..3206143 1 NC_009525.1 transcriptional regulatory protein 3206143 5213056 MRA_2909 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001284251.1 3205385 D 419947 CDS YP_001284252.1 148662729 5213057 complement(3206158..3207540) 1 NC_009525.1 IS1539 transposase 3207540 5213057 MRA_2910 Mycobacterium tuberculosis H37Ra IS1539 transposase YP_001284252.1 3206158 R 419947 CDS YP_001284253.1 148662730 5213058 complement(3207537..3208424) 1 NC_009525.1 IS1539 resolvase 3208424 5213058 MRA_2911 Mycobacterium tuberculosis H37Ra IS1539 resolvase YP_001284253.1 3207537 R 419947 CDS YP_001284254.1 148662731 5214592 3208423..3208842 1 NC_009525.1 transcriptional regulatory protein 3208842 5214592 MRA_2912 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001284254.1 3208423 D 419947 CDS YP_001284255.1 148662732 5214593 complement(3208856..3210277) 1 NC_009525.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 3210277 amiC 5214593 amiC Mycobacterium tuberculosis H37Ra amidase YP_001284255.1 3208856 R 419947 CDS YP_001284256.1 148662733 5214594 complement(3210284..3211099) 1 NC_009525.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 3211099 tsf 5214594 tsf Mycobacterium tuberculosis H37Ra elongation factor Ts YP_001284256.1 3210284 R 419947 CDS YP_001284257.1 148662734 5214595 complement(3211111..3211974) 1 NC_009525.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 3211974 rpsB 5214595 rpsB Mycobacterium tuberculosis H37Ra 30S ribosomal protein S2 YP_001284257.1 3211111 R 419947 CDS YP_001284258.1 148662735 5214596 3212258..3213007 1 NC_009525.1 hypothetical protein 3213007 5214596 MRA_2916 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284258.1 3212258 D 419947 CDS YP_001284259.1 148662736 5214597 complement(3212786..3214012) 1 NC_009525.1 PPE family protein 3214012 5214597 MRA_2917 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284259.1 3212786 R 419947 CDS YP_001284260.1 148662737 5214598 3214412..3215389 1 NC_009525.1 oxidoreductase 3215389 5214598 MRA_2918 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284260.1 3214412 D 419947 CDS YP_001284261.1 148662738 5214599 complement(3215386..3216282) 1 NC_009525.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 3216282 xerC 5214599 xerC Mycobacterium tuberculosis H37Ra site-specific tyrosine recombinase XerC YP_001284261.1 3215386 R 419947 CDS YP_001284262.1 148662739 5214600 complement(3216373..3217224) 1 NC_009525.1 siderophore utilization protein 3217224 viuB 5214600 viuB Mycobacterium tuberculosis H37Ra siderophore utilization protein YP_001284262.1 3216373 R 419947 CDS YP_001284263.1 148662740 5213698 complement(3217257..3218426) 1 NC_009525.1 hypothetical protein 3218426 5213698 MRA_2921 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284263.1 3217257 R 419947 CDS YP_001284264.1 148662741 5213699 complement(3218423..3219934) 1 NC_009525.1 magnesium chelatase 3219934 5213699 MRA_2922 Mycobacterium tuberculosis H37Ra magnesium chelatase YP_001284264.1 3218423 R 419947 CDS YP_001284265.1 148662742 5213700 complement(3219934..3220320) 1 NC_009525.1 hypothetical protein 3220320 5213700 MRA_2923 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284265.1 3219934 R 419947 CDS YP_001284266.1 148662743 5213701 complement(3220568..3221398) 1 NC_009525.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 3221398 fdhD 5213701 fdhD Mycobacterium tuberculosis H37Ra formate dehydrogenase accessory protein YP_001284266.1 3220568 R 419947 CDS YP_001284267.1 148662744 5213702 complement(3221398..3223737) 1 NC_009525.1 formate dehydrogenease subunit alpha 3223737 fdhF 5213702 fdhF Mycobacterium tuberculosis H37Ra formate dehydrogenease subunit alpha YP_001284267.1 3221398 R 419947 CDS YP_001284268.1 148662745 5213703 complement(3223795..3224100) 1 NC_009525.1 hypothetical protein 3224100 5213703 MRA_2926 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284268.1 3223795 R 419947 CDS YP_001284269.1 148662746 5213704 complement(3224154..3224948) 1 NC_009525.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 3224948 rnhB 5213704 rnhB Mycobacterium tuberculosis H37Ra ribonuclease HII YP_001284269.1 3224154 R 419947 CDS YP_001284270.1 148662747 5213705 complement(3224962..3225846) 1 NC_009525.1 signal peptidase I 3225846 lepB 5213705 lepB Mycobacterium tuberculosis H37Ra signal peptidase I YP_001284270.1 3224962 R 419947 CDS YP_001284271.1 148662748 5213706 complement(3225904..3226245) 1 NC_009525.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 3226245 rplS 5213706 rplS Mycobacterium tuberculosis H37Ra 50S ribosomal protein L19 YP_001284271.1 3225904 R 419947 CDS YP_001284272.1 148662749 5213784 3226620..3227564 1 NC_009525.1 alanine rich lipoprotein LppW 3227564 lppW 5213784 lppW Mycobacterium tuberculosis H37Ra alanine rich lipoprotein LppW YP_001284272.1 3226620 D 419947 CDS YP_001284273.1 148662750 5213785 complement(3227657..3228349) 1 NC_009525.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 3228349 trmD 5213785 trmD Mycobacterium tuberculosis H37Ra tRNA (guanine-N(1)-)-methyltransferase YP_001284273.1 3227657 R 419947 CDS YP_001284274.1 148662751 5213786 complement(3228353..3228883) 1 NC_009525.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 3228883 rimM 5213786 rimM Mycobacterium tuberculosis H37Ra 16S rRNA-processing protein RimM YP_001284274.1 3228353 R 419947 CDS YP_001284275.1 148662752 5213787 complement(3228897..3229139) 1 NC_009525.1 hypothetical protein 3229139 5213787 MRA_2933 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284275.1 3228897 R 419947 CDS YP_001284276.1 148662753 5213788 complement(3229147..3229635) 1 NC_009525.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 3229635 rpsP 5213788 rpsP Mycobacterium tuberculosis H37Ra 30S ribosomal protein S16 YP_001284276.1 3229147 R 419947 CDS YP_001284277.1 148662754 5213789 complement(3229819..3230262) 1 NC_009525.1 hypothetical protein 3230262 5213789 MRA_2935 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284277.1 3229819 R 419947 CDS YP_001284278.1 148662755 5213790 3230331..3231206 1 NC_009525.1 D-alanyl-D-alanine carboxypeptidase DacB2 3231206 dacB2 5213790 dacB2 Mycobacterium tuberculosis H37Ra D-alanyl-D-alanine carboxypeptidase DacB2 YP_001284278.1 3230331 D 419947 CDS YP_001284279.1 148662756 5213791 complement(3231266..3231853) 1 NC_009525.1 TetR family transcriptional regulator 3231853 5213791 MRA_2937 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284279.1 3231266 R 419947 CDS YP_001284280.1 148662757 5213792 complement(3231855..3233690) 1 NC_009525.1 D-amino acid aminohydrolase 3233690 5213792 MRA_2938 Mycobacterium tuberculosis H37Ra D-amino acid aminohydrolase YP_001284280.1 3231855 R 419947 CDS YP_001284281.1 148662758 5215483 complement(3233759..3235516) 1 NC_009525.1 serine/threonine protein kinase 3235516 pknI 5215483 pknI Mycobacterium tuberculosis H37Ra serine/threonine protein kinase YP_001284281.1 3233759 R 419947 CDS YP_001284282.1 148662759 5215484 complement(3235560..3236672) 1 NC_009525.1 hypothetical protein 3236672 5215484 MRA_2940 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284282.1 3235560 R 419947 CDS YP_001284283.1 148662760 5215485 complement(3236700..3238277) 1 NC_009525.1 signal recognition particle protein Ffh 3238277 ffh 5215485 ffh Mycobacterium tuberculosis H37Ra signal recognition particle protein Ffh YP_001284283.1 3236700 R 419947 CDS YP_001284284.1 148662761 5215486 3238355..3240235 1 NC_009525.1 hypothetical protein 3240235 5215486 MRA_2942 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284284.1 3238355 D 419947 CDS YP_001284285.1 148662762 5215487 complement(3240246..3242672) 1 NC_009525.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK; PII uridylyl-transferase 3242672 glnD 5215487 glnD Mycobacterium tuberculosis H37Ra PII uridylyl-transferase YP_001284285.1 3240246 R 419947 CDS YP_001284286.1 148662763 5215488 complement(3242730..3243068) 1 NC_009525.1 nitrogen regulatory protein P-II GlnB 3243068 glnB 5215488 glnB Mycobacterium tuberculosis H37Ra nitrogen regulatory protein P-II GlnB YP_001284286.1 3242730 R 419947 CDS YP_001284287.1 148662764 5215489 complement(3243065..3244498) 1 NC_009525.1 ammonium-transport integral membrane protein Amt 3244498 amt 5215489 amt Mycobacterium tuberculosis H37Ra ammonium-transport integral membrane protein Amt YP_001284287.1 3243065 R 419947 CDS YP_001284288.1 148662765 5215490 complement(3244863..3246131) 1 NC_009525.1 signal recognition particle FtsY 3246131 ftsY 5215490 ftsY Mycobacterium tuberculosis H37Ra signal recognition particle FtsY YP_001284288.1 3244863 R 419947 CDS YP_001284289.1 148662766 5212656 complement(3246181..3249798) 1 NC_009525.1 chromosome segregation SMC protein 3249798 smc 5212656 smc Mycobacterium tuberculosis H37Ra chromosome segregation SMC protein YP_001284289.1 3246181 R 419947 CDS YP_001284290.1 148662767 5212657 complement(3249810..3250091) 1 NC_009525.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 3250091 acyP 5212657 acyP Mycobacterium tuberculosis H37Ra acylphosphatase YP_001284290.1 3249810 R 419947 CDS YP_001284291.1 148662768 5212658 complement(3250078..3250491) 1 NC_009525.1 hypothetical protein 3250491 5212658 MRA_2949 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284291.1 3250078 R 419947 CDS YP_001284292.1 148662769 5212659 complement(3250593..3251462) 1 NC_009525.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 3251462 fpg 5212659 fpg Mycobacterium tuberculosis H37Ra formamidopyrimidine-DNA glycosylase YP_001284292.1 3250593 R 419947 CDS YP_001284293.1 148662770 5212660 complement(3251507..3251698) 1 NC_009525.1 hypothetical protein 3251698 5212660 MRA_2951 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284293.1 3251507 R 419947 CDS YP_001284294.1 148662771 5212661 complement(3251821..3252543) 1 NC_009525.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 3252543 rnc 5212661 rnc Mycobacterium tuberculosis H37Ra ribonuclease III YP_001284294.1 3251821 R 419947 CDS YP_001284295.1 148662772 5212662 complement(3252540..3253163) 1 NC_009525.1 hypothetical protein 3253163 5212662 MRA_2953 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284295.1 3252540 R 419947 CDS YP_001284296.1 148662773 5212663 complement(3253214..3253951) 1 NC_009525.1 hypothetical protein 3253951 5212663 MRA_2954 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284296.1 3253214 R 419947 CDS YP_001284297.1 148662774 5212664 3254190..3254975 1 NC_009525.1 thioesterase 3254975 tesA 5212664 tesA Mycobacterium tuberculosis H37Ra thioesterase YP_001284297.1 3254190 D 419947 CDS YP_001284298.1 148662775 5212515 3254962..3255273 1 NC_009525.1 hypothetical protein 3255273 5212515 MRA_2955A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284298.1 3254962 D 419947 CDS YP_001284299.1 148662776 5212516 3255689..3257440 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3257440 fadD26 5212516 fadD26 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001284299.1 3255689 D 419947 CDS YP_001284300.1 148662777 5212517 3257437..3263067 1 NC_009525.1 phenolpthiocerol synthesis type-I polyketide synthase PpsA 3263067 ppsA 5212517 ppsA Mycobacterium tuberculosis H37Ra phenolpthiocerol synthesis type-I polyketide synthase PpsA YP_001284300.1 3257437 D 419947 CDS YP_001284301.1 148662778 5212518 3263064..3267680 1 NC_009525.1 phenolpthiocerol synthesis type-I polyketide synthase PpsB 3267680 ppsB 5212518 ppsB Mycobacterium tuberculosis H37Ra phenolpthiocerol synthesis type-I polyketide synthase PpsB YP_001284301.1 3263064 D 419947 CDS YP_001284302.1 148662779 5212519 3267677..3274243 1 NC_009525.1 phenolpthiocerol synthesis type-I polyketide synthase PpsC 3274243 ppsC 5212519 ppsC Mycobacterium tuberculosis H37Ra phenolpthiocerol synthesis type-I polyketide synthase PpsC YP_001284302.1 3267677 D 419947 CDS YP_001284303.1 148662780 5212520 3274240..3279723 1 NC_009525.1 phenolpthiocerol synthesis type-I polyketide synthase PpsD 3279723 ppsD 5212520 ppsD Mycobacterium tuberculosis H37Ra phenolpthiocerol synthesis type-I polyketide synthase PpsD YP_001284303.1 3274240 D 419947 CDS YP_001284304.1 148662781 5212521 3279729..3284195 1 NC_009525.1 phenolpthiocerol synthesis type-I polyketide synthase PpsD 3284195 ppsE 5212521 ppsE Mycobacterium tuberculosis H37Ra phenolpthiocerol synthesis type-I polyketide synthase PpsD YP_001284304.1 3279729 D 419947 CDS YP_001284305.1 148662782 5212522 3284206..3285201 1 NC_009525.1 daunorubicin-dim ABC transporter ATP-binding protein DrrA 3285201 drrA 5212522 drrA Mycobacterium tuberculosis H37Ra daunorubicin-dim ABC transporter ATP-binding protein DrrA YP_001284305.1 3284206 D 419947 CDS YP_001284306.1 148662783 5212523 3285198..3286067 1 NC_009525.1 daunorubicin-dim ABC transporter permease DrrB 3286067 drrB 5212523 drrB Mycobacterium tuberculosis H37Ra daunorubicin-dim ABC transporter permease DrrB YP_001284306.1 3285198 D 419947 CDS YP_001284307.1 148662784 5213524 3286064..3286894 1 NC_009525.1 daunorubicin-dim ABC transporter permease DrrC 3286894 drrC 5213524 drrC Mycobacterium tuberculosis H37Ra daunorubicin-dim ABC transporter permease DrrC YP_001284307.1 3286064 D 419947 CDS YP_001284308.1 148662785 5213525 3286941..3288209 1 NC_009525.1 required for PDIM synthesis; phthiocerol and phthiodiolone dimycocerosate esters are scaffolds used for virulence-enhancing lipids; proposed to catalyze diesterification of phthiocerol and phthiodolone with mycocerosate; functions in polyketide synthesis; acyltransferase 3288209 papA5 5213525 papA5 Mycobacterium tuberculosis H37Ra acyltransferase YP_001284308.1 3286941 D 419947 CDS YP_001284309.1 148662786 5213526 complement(3288372..3294707) 1 NC_009525.1 multifunctional mycocerosic acid synthase membrane-associated Mas 3294707 mas 5213526 mas Mycobacterium tuberculosis H37Ra multifunctional mycocerosic acid synthase membrane-associated Mas YP_001284309.1 3288372 R 419947 CDS YP_001284310.1 148662787 5213527 3295327..3297069 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3297069 fadD28 5213527 fadD28 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001284310.1 3295327 D 419947 CDS YP_001284311.1 148662788 5213528 3297062..3299824 1 NC_009525.1 transmembrane transport protein MmpL7 3299824 mmpL7 5213528 mmpL7 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL7 YP_001284311.1 3297062 D 419947 CDS YP_001284312.1 148662789 5213529 3300456..3301697 1 NC_009525.1 ISMt3 transposase A 3301697 5213529 MRA_2969 Mycobacterium tuberculosis H37Ra ISMt3 transposase A YP_001284312.1 3300456 D 419947 CDS YP_001284313.1 148662790 5213530 3301697..3302227 1 NC_009525.1 ISMt3 transposase B1 3302227 5213530 MRA_2970 Mycobacterium tuberculosis H37Ra ISMt3 transposase B1 YP_001284313.1 3301697 D 419947 CDS YP_001284314.1 148662791 5213531 3301782..3302498 1 NC_009525.1 ISMt3 transposase B2 3302498 5213531 MRA_2971 Mycobacterium tuberculosis H37Ra ISMt3 transposase B2 YP_001284314.1 3301782 D 419947 CDS YP_001284315.1 148662792 5213532 complement(3302616..3303317) 1 NC_009525.1 lipoprotein LppX 3303317 lppX 5213532 lppX Mycobacterium tuberculosis H37Ra lipoprotein LppX YP_001284315.1 3302616 R 419947 CDS YP_001284316.1 148662793 5212915 complement(3303495..3308345) 1 NC_009525.1 polyketide synthase Pks1 3308345 pks1 5212915 pks1 Mycobacterium tuberculosis H37Ra polyketide synthase Pks1 YP_001284316.1 3303495 R 419947 CDS YP_001284317.1 148662794 5212916 complement(3308342..3309832) 1 NC_009525.1 polyketide synthase 3309832 pks15 5212916 pks15 Mycobacterium tuberculosis H37Ra polyketide synthase YP_001284317.1 3308342 R 419947 CDS YP_001284318.1 148662795 5212917 complement(3309829..3311946) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3311946 fadD22 5212917 fadD22 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001284318.1 3309829 R 419947 CDS YP_001284319.1 148662796 5212918 complement(3311963..3312562) 1 NC_009525.1 hypothetical protein 3312562 5212918 MRA_2976 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284319.1 3311963 R 419947 CDS YP_001284320.1 148662797 5212919 complement(3312588..3314447) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3314447 fadD29 5212919 fadD29 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001284320.1 3312588 R 419947 CDS YP_001284321.1 148662798 5212920 complement(3315095..3316240) 1 NC_009525.1 N5,N10-methylenetetrahydromethanopterin reductase-related protein 3316240 5212920 MRA_2978 Mycobacterium tuberculosis H37Ra N5,N10-methylenetetrahydromethanopterin reductase-related protein YP_001284321.1 3315095 R 419947 CDS YP_001284322.1 148662799 5212921 3316433..3317245 1 NC_009525.1 methyltransferase 3317245 5212921 MRA_2979 Mycobacterium tuberculosis H37Ra methyltransferase YP_001284322.1 3316433 D 419947 CDS YP_001284323.1 148662800 5212922 3317271..3318527 1 NC_009525.1 hypothetical protein 3318527 5212922 MRA_2980 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284323.1 3317271 D 419947 CDS YP_001284324.1 148662801 5212466 complement(3318658..3319383) 1 NC_009525.1 hypothetical protein 3319383 5212466 MRA_2981 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284324.1 3318658 R 419947 CDS YP_001284325.1 148662802 5212467 complement(3319572..3320537) 1 NC_009525.1 hypothetical protein 3320537 5212467 MRA_2982 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284325.1 3319572 R 419947 CDS YP_001284326.1 148662803 5212468 3320660..3321391 1 NC_009525.1 hypothetical protein 3321391 5212468 MRA_2983 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284326.1 3320660 D 419947 CDS YP_001284327.1 148662804 5212469 3321462..3322289 1 NC_009525.1 glycosyl transferase 3322289 5212469 MRA_2984 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001284327.1 3321462 D 419947 CDS YP_001284328.1 148662805 5212470 complement(3322706..3323992) 1 NC_009525.1 UDP-glucoronosyl and UDP-glucosyltransferase 3323992 5212470 MRA_2985 Mycobacterium tuberculosis H37Ra UDP-glucoronosyl and UDP-glucosyltransferase YP_001284328.1 3322706 R 419947 CDS YP_001284329.1 148662806 5212471 complement(3324093..3324830) 1 NC_009525.1 methyltransferase 3324830 5212471 MRA_2986 Mycobacterium tuberculosis H37Ra methyltransferase YP_001284329.1 3324093 R 419947 CDS YP_001284330.1 148662807 5212472 complement(3324945..3325193) 1 NC_009525.1 hypothetical protein 3325193 5212472 MRA_2987 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284330.1 3324945 R 419947 CDS YP_001284331.1 148662808 5212473 complement(3325308..3325721) 1 NC_009525.1 hypothetical protein 3325721 5212473 MRA_2988 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284331.1 3325308 R 419947 CDS YP_001284332.1 148662809 5212474 complement(3325765..3327114) 1 NC_009525.1 UDP-glucoronosyl and UDP-glucosyltransferase 3327114 5212474 MRA_2989 Mycobacterium tuberculosis H37Ra UDP-glucoronosyl and UDP-glucosyltransferase YP_001284332.1 3325765 R 419947 CDS YP_001284333.1 148662810 5211873 3327228..3328448 1 NC_009525.1 integral membrane protein 3328448 5211873 MRA_2990 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284333.1 3327228 D 419947 CDS YP_001284334.1 148662811 5211874 3328521..3329453 1 NC_009525.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 3329453 purU 5211874 purU Mycobacterium tuberculosis H37Ra formyltetrahydrofolate deformylase YP_001284334.1 3328521 D 419947 CDS YP_001284335.1 148662812 5211875 3329907..3330278 1 NC_009525.1 hypothetical protein 3330278 5211875 MRA_2992 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284335.1 3329907 D 419947 CDS YP_001284336.1 148662813 5211876 complement(3330322..3330807) 1 NC_009525.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3330807 coaD 5211876 coaD Mycobacterium tuberculosis H37Ra phosphopantetheine adenylyltransferase YP_001284336.1 3330322 R 419947 CDS YP_001284337.1 148662814 5211877 complement(3330893..3331459) 1 NC_009525.1 methyltransferase 3331459 5211877 MRA_2994 Mycobacterium tuberculosis H37Ra methyltransferase YP_001284337.1 3330893 R 419947 CDS YP_001284338.1 148662815 5211878 complement(3331655..3335038) 1 NC_009525.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 3335038 pca 5211878 pca Mycobacterium tuberculosis H37Ra pyruvate carboxylase YP_001284338.1 3331655 R 419947 CDS YP_001284339.1 148662816 5211879 complement(3335063..3335695) 1 NC_009525.1 integral membrane protein 3335695 5211879 MRA_2996 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284339.1 3335063 R 419947 CDS YP_001284340.1 148662817 5211880 complement(3335701..3336468) 1 NC_009525.1 hypothetical protein 3336468 5211880 MRA_2997 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284340.1 3335701 R 419947 CDS YP_001284341.1 148662818 5211881 complement(3336565..3337695) 1 NC_009525.1 lipase/esterase 3337695 lipN 5211881 lipN Mycobacterium tuberculosis H37Ra lipase/esterase YP_001284341.1 3336565 R 419947 CDS YP_001284342.1 148662819 5212365 3337926..3338096 1 NC_009525.1 hypothetical protein 3338096 5212365 MRA_2998A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284342.1 3337926 D 419947 CDS YP_001284343.1 148662820 5212366 3338093..3338941 1 NC_009525.1 oxidoreductase 3338941 5212366 MRA_2999 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284343.1 3338093 D 419947 CDS YP_001284344.1 148662821 5212367 complement(3339015..3339728) 1 NC_009525.1 hypothetical protein 3339728 5212367 MRA_3000 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284344.1 3339015 R 419947 CDS YP_001284345.1 148662822 5212368 complement(3339725..3341938) 1 NC_009525.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3341938 recG 5212368 recG Mycobacterium tuberculosis H37Ra ATP-dependent DNA helicase RecG YP_001284345.1 3339725 R 419947 CDS YP_001284346.1 148662823 5212369 complement(3341941..3343353) 1 NC_009525.1 hypothetical protein 3343353 5212369 MRA_3002 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284346.1 3341941 R 419947 CDS YP_001284347.1 148662824 5212370 complement(3343350..3343604) 1 NC_009525.1 hypothetical protein 3343604 5212370 MRA_3003 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284347.1 3343350 R 419947 CDS YP_001284348.1 148662825 5212371 3343846..3344040 1 NC_009525.1 required for 70S ribosome assembly; 50S ribosomal protein L28 3344040 rpmB 5212371 rpmB Mycobacterium tuberculosis H37Ra 50S ribosomal protein L28 YP_001284348.1 3343846 D 419947 CDS YP_001284349.1 148662826 5212372 complement(3344063..3344746) 1 NC_009525.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3344746 ung 5212372 ung Mycobacterium tuberculosis H37Ra uracil-DNA glycosylase YP_001284349.1 3344063 R 419947 CDS YP_001284350.1 148662827 5212373 complement(3344779..3345780) 1 NC_009525.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 3345780 thiL 5212373 thiL Mycobacterium tuberculosis H37Ra thiamine monophosphate kinase YP_001284350.1 3344779 R 419947 CDS YP_001284351.1 148662828 5213903 complement(3345777..3347156) 1 NC_009525.1 IS1538 transposase 3347156 5213903 MRA_3007 Mycobacterium tuberculosis H37Ra IS1538 transposase YP_001284351.1 3345777 R 419947 CDS YP_001284352.1 148662829 5213904 complement(3347156..3347740) 1 NC_009525.1 IS1538 resolvase 3347740 5213904 MRA_3008 Mycobacterium tuberculosis H37Ra IS1538 resolvase YP_001284352.1 3347156 R 419947 CDS YP_001284353.1 148662830 5213905 3347952..3348497 1 NC_009525.1 hypothetical protein 3348497 5213905 MRA_3009 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284353.1 3347952 D 419947 CDS YP_001284354.1 148662831 5213906 complement(3348965..3350086) 1 NC_009525.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 3350086 ddl 5213906 ddl Mycobacterium tuberculosis H37Ra D-alanyl-alanine synthetase A YP_001284354.1 3348965 R 419947 CDS YP_001284355.1 148662832 5213907 complement(3350164..3351168) 1 NC_009525.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3351168 gpsA 5213907 gpsA Mycobacterium tuberculosis H37Ra NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001284355.1 3350164 R 419947 CDS YP_001284356.1 148662833 5213908 3351287..3351931 1 NC_009525.1 hypothetical protein 3351931 5213908 MRA_3012 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284356.1 3351287 D 419947 CDS YP_001284357.1 148662834 5213909 3352023..3354251 1 NC_009525.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3354251 ppk 5213909 ppk Mycobacterium tuberculosis H37Ra polyphosphate kinase YP_001284357.1 3352023 D 419947 CDS YP_001284358.1 148662835 5213910 3354334..3355287 1 NC_009525.1 hydrolase MutT1 3355287 mutT1 5213910 mutT1 Mycobacterium tuberculosis H37Ra hydrolase MutT1 YP_001284358.1 3354334 D 419947 CDS YP_001284359.1 148662836 5213911 complement(3355345..3355989) 1 NC_009525.1 histone-like protein; DNA-binding protein hupB 3355989 hupB 5213911 hupB Mycobacterium tuberculosis H37Ra DNA-binding protein hupB YP_001284359.1 3355345 R 419947 CDS YP_001284360.1 148662837 5214120 complement(3356202..3356798) 1 NC_009525.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 3356798 leuD 5214120 leuD Mycobacterium tuberculosis H37Ra isopropylmalate isomerase small subunit YP_001284360.1 3356202 R 419947 CDS YP_001284361.1 148662838 5214121 complement(3356823..3358244) 1 NC_009525.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 3358244 leuC 5214121 leuC Mycobacterium tuberculosis H37Ra isopropylmalate isomerase large subunit YP_001284361.1 3356823 R 419947 CDS YP_001284362.1 148662839 5214122 3358316..3359017 1 NC_009525.1 IclR family transcriptional regulator 3359017 5214122 MRA_3018 Mycobacterium tuberculosis H37Ra IclR family transcriptional regulator YP_001284362.1 3358316 D 419947 CDS YP_001284363.1 148662840 5214123 complement(3359028..3359888) 1 NC_009525.1 hypothetical protein 3359888 5214123 MRA_3019 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284363.1 3359028 R 419947 CDS YP_001284364.1 148662841 5214124 3360151..3360642 1 NC_009525.1 hypothetical protein 3360642 5214124 MRA_3020 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284364.1 3360151 D 419947 CDS YP_001284365.1 148662842 5214127 complement(3360974..3362446) 1 NC_009525.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 3362446 gltX 5214127 gltX Mycobacterium tuberculosis H37Ra glutamyl-tRNA synthetase YP_001284365.1 3360974 R 419947 CDS YP_001284366.1 148662843 5214991 complement(3362443..3363162) 1 NC_009525.1 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 3363162 5214991 MRA_3022 Mycobacterium tuberculosis H37Ra 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase YP_001284366.1 3362443 R 419947 CDS YP_001284367.1 148662844 5214992 3363438..3364775 1 NC_009525.1 integral membrane protein 3364775 5214992 MRA_3023 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284367.1 3363438 D 419947 CDS YP_001284368.1 148662845 5214993 complement(3364627..3365637) 1 NC_009525.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 3365637 leuB 5214993 leuB Mycobacterium tuberculosis H37Ra 3-isopropylmalate dehydrogenase YP_001284368.1 3364627 R 419947 CDS YP_001284369.1 148662846 5214994 complement(3365652..3367238) 1 NC_009525.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3367238 serA1 5214994 serA1 Mycobacterium tuberculosis H37Ra D-3-phosphoglycerate dehydrogenase YP_001284369.1 3365652 R 419947 CDS YP_001284370.1 148662847 5214995 3367268..3368710 1 NC_009525.1 alanine rich dehydrogenase 3368710 5214995 MRA_3026 Mycobacterium tuberculosis H37Ra alanine rich dehydrogenase YP_001284370.1 3367268 D 419947 CDS YP_001284371.1 148662848 5214996 3368984..3369445 1 NC_009525.1 hypothetical protein 3369445 5214996 MRA_3027 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284371.1 3368984 D 419947 CDS YP_001284372.1 148662849 5214997 3369771..3370736 1 NC_009525.1 lipoprotein LppY 3370736 lppY 5214997 lppY Mycobacterium tuberculosis H37Ra lipoprotein LppY YP_001284372.1 3369771 D 419947 CDS YP_001284373.1 148662850 5215320 3370781..3371440 1 NC_009525.1 transmembrane protein 3371440 5215320 MRA_3029 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284373.1 3370781 D 419947 CDS YP_001284374.1 148662851 5215321 complement(3371489..3371707) 1 NC_009525.1 hypothetical protein 3371707 5215321 MRA_3030 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284374.1 3371489 R 419947 CDS YP_001284375.1 148662852 5215322 complement(3371754..3372755) 1 NC_009525.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 3372755 ilvC 5215322 ilvC Mycobacterium tuberculosis H37Ra ketol-acid reductoisomerase YP_001284375.1 3371754 R 419947 CDS YP_001284376.1 148662853 5215323 complement(3372793..3373299) 1 NC_009525.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 3373299 ilvH 5215323 ilvH Mycobacterium tuberculosis H37Ra acetolactate synthase 3 regulatory subunit YP_001284376.1 3372793 R 419947 CDS YP_001284377.1 148662854 5215324 complement(3373299..3375155) 1 NC_009525.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit 3375155 ilvB1 5215324 ilvB1 Mycobacterium tuberculosis H37Ra acetolactate synthase 1 catalytic subunit YP_001284377.1 3373299 R 419947 CDS YP_001284378.1 148662855 5215325 3375517..3375855 1 NC_009525.1 antigen Cfp6 3375855 cfp6 5215325 cfp6 Mycobacterium tuberculosis H37Ra antigen Cfp6 YP_001284378.1 3375517 D 419947 CDS YP_001284379.1 148662856 5215326 complement(3375862..3376701) 1 NC_009525.1 hypothetical protein 3376701 5215326 MRA_3035 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284379.1 3375862 R 419947 CDS YP_001284380.1 148662857 5215327 3376878..3377999 1 NC_009525.1 lipoprotein LppZ 3377999 lppZ 5215327 lppZ Mycobacterium tuberculosis H37Ra lipoprotein LppZ YP_001284380.1 3376878 D 419947 CDS YP_001284381.1 148662858 5215328 complement(3378005..3378619) 1 NC_009525.1 oxidoreductase 3378619 5215328 MRA_3037 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284381.1 3378005 R 419947 CDS YP_001284382.1 148662859 5215443 3378813..3379436 1 NC_009525.1 hypothetical protein 3379436 5215443 MRA_3038 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284382.1 3378813 D 419947 CDS YP_001284383.1 148662860 5215444 complement(3379433..3380962) 1 NC_009525.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 3380962 gatB 5215444 gatB Mycobacterium tuberculosis H37Ra aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001284383.1 3379433 R 419947 CDS YP_001284384.1 148662861 5215445 complement(3380992..3382023) 1 NC_009525.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 3382023 pfkA 5215445 pfkA Mycobacterium tuberculosis H37Ra 6-phosphofructokinase YP_001284384.1 3380992 R 419947 CDS YP_001284385.1 148662862 5215446 complement(3382119..3383603) 1 NC_009525.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 3383603 gatA 5215446 gatA Mycobacterium tuberculosis H37Ra aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001284385.1 3382119 R 419947 CDS YP_001284386.1 148662863 5215447 complement(3383600..3383899) 1 NC_009525.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 3383899 gatC 5215447 gatC Mycobacterium tuberculosis H37Ra aspartyl/glutamyl-tRNA amidotransferase subunit C YP_001284386.1 3383600 R 419947 CDS YP_001284387.1 148662864 5215448 3383984..3384640 1 NC_009525.1 hypothetical protein 3384640 5215448 MRA_3043 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284387.1 3383984 D 419947 CDS YP_001284388.1 148662865 5215449 complement(3384714..3386789) 1 NC_009525.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 3386789 ligA 5215449 ligA Mycobacterium tuberculosis H37Ra NAD-dependent DNA ligase LigA YP_001284388.1 3384714 R 419947 CDS YP_001284389.1 148662866 5215450 complement(3386820..3387833) 1 NC_009525.1 hypothetical protein 3387833 5215450 MRA_3045 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284389.1 3386820 R 419947 CDS YP_001284390.1 148662867 5215451 3387927..3388556 1 NC_009525.1 lipoprotein LpqA 3388556 lpqA 5215451 lpqA Mycobacterium tuberculosis H37Ra lipoprotein LpqA YP_001284390.1 3387927 D 419947 CDS YP_001284391.1 148662868 5211897 complement(3388659..3389021) 1 NC_009525.1 esat-6 like protein EsxQ 3389021 esxQ 5211897 esxQ Mycobacterium tuberculosis H37Ra esat-6 like protein EsxQ YP_001284391.1 3388659 R 419947 CDS YP_001284392.1 148662869 5211898 complement(3389108..3390412) 1 NC_009525.1 PPE family protein 3390412 5211898 MRA_3048 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284392.1 3389108 R 419947 CDS YP_001284393.1 148662870 5211899 complement(3390498..3390782) 1 NC_009525.1 PPE family protein 3390782 5211899 MRA_3049 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284393.1 3390498 R 419947 CDS YP_001284394.1 148662871 5211900 complement(3390880..3391170) 1 NC_009525.1 secreted esat-6 like protein EsxR 3391170 esxR 5211900 esxR Mycobacterium tuberculosis H37Ra secreted esat-6 like protein EsxR YP_001284394.1 3390880 R 419947 CDS YP_001284395.1 148662872 5211901 complement(3391205..3391498) 1 NC_009525.1 PE family protein 3391498 5211901 MRA_3051 Mycobacterium tuberculosis H37Ra PE family protein YP_001284395.1 3391205 R 419947 CDS YP_001284396.1 148662873 5211902 complement(3391545..3392852) 1 NC_009525.1 PPE family protein 3392852 5211902 MRA_3052 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284396.1 3391545 R 419947 CDS YP_001284397.1 148662874 5211903 complement(3392849..3393163) 1 NC_009525.1 PE family protein 3393163 5211903 MRA_3053 Mycobacterium tuberculosis H37Ra PE family protein YP_001284397.1 3392849 R 419947 CDS YP_001284398.1 148662875 5211904 complement(3393545..3394792) 1 NC_009525.1 IS1081 transposase 3394792 5211904 MRA_3054 Mycobacterium tuberculosis H37Ra IS1081 transposase YP_001284398.1 3393545 R 419947 CDS YP_001284399.1 148662876 5211905 complement(3394955..3396058) 1 NC_009525.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 3396058 mnmA 5211905 mnmA Mycobacterium tuberculosis H37Ra tRNA-specific 2-thiouridylase MnmA YP_001284399.1 3394955 R 419947 CDS YP_001284400.1 148662877 5211970 complement(3396055..3397236) 1 NC_009525.1 cysteine desulfurase IscS 3397236 iscS 5211970 iscS Mycobacterium tuberculosis H37Ra cysteine desulfurase IscS YP_001284400.1 3396055 R 419947 CDS YP_001284401.1 148662878 5211971 complement(3397333..3398247) 1 NC_009525.1 hypothetical protein 3398247 5211971 MRA_3057 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284401.1 3397333 R 419947 CDS YP_001284402.1 148662879 5211972 complement(3398244..3398984) 1 NC_009525.1 hypothetical protein 3398984 5211972 MRA_3058 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284402.1 3398244 R 419947 CDS YP_001284403.1 148662880 5211973 complement(3399245..3400201) 1 NC_009525.1 electron transfer flavoprotein subunit alpha 3400201 fixB 5211973 fixB Mycobacterium tuberculosis H37Ra electron transfer flavoprotein subunit alpha YP_001284403.1 3399245 R 419947 CDS YP_001284404.1 148662881 5211974 complement(3400240..3401040) 1 NC_009525.1 electron transfer flavoprotein subunit beta 3401040 fixA 5211974 fixA Mycobacterium tuberculosis H37Ra electron transfer flavoprotein subunit beta YP_001284404.1 3400240 R 419947 CDS YP_001284405.1 148662882 5211975 3401271..3402095 1 NC_009525.1 hypothetical protein 3402095 5211975 MRA_3061 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284405.1 3401271 D 419947 CDS YP_001284406.1 148662883 5211976 3402092..3403672 1 NC_009525.1 hypothetical protein 3403672 5211976 MRA_3062 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284406.1 3402092 D 419947 CDS YP_001284407.1 148662884 5211977 3403704..3404948 1 NC_009525.1 glycosyl transferase 3404948 5211977 MRA_3063 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001284407.1 3403704 D 419947 CDS YP_001284408.1 148662885 5211978 3404982..3405371 1 NC_009525.1 hypothetical protein 3405371 5211978 MRA_3064 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284408.1 3404982 D 419947 CDS YP_001284409.1 148662886 5212055 3405550..3406098 1 NC_009525.1 hypothetical protein 3406098 5212055 MRA_3065 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284409.1 3405550 D 419947 CDS YP_001284410.1 148662887 5212056 complement(3406189..3407091) 1 NC_009525.1 hexapeptide transferase 3407091 5212056 MRA_3066 Mycobacterium tuberculosis H37Ra hexapeptide transferase YP_001284410.1 3406189 R 419947 CDS YP_001284411.1 148662888 5212057 3407549..3408631 1 NC_009525.1 hypothetical protein 3408631 5212057 MRA_3067 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284411.1 3407549 D 419947 CDS YP_001284412.1 148662889 5212058 complement(3408628..3409311) 1 NC_009525.1 hypothetical protein 3409311 5212058 MRA_3068 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284412.1 3408628 R 419947 CDS YP_001284413.1 148662890 5212059 complement(3409384..3410460) 1 NC_009525.1 hypothetical protein 3410460 5212059 MRA_3069 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284413.1 3409384 R 419947 CDS YP_001284414.1 148662891 5212060 complement(3410595..3411578) 1 NC_009525.1 hypothetical protein 3411578 5212060 MRA_3070 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284414.1 3410595 R 419947 CDS YP_001284415.1 148662892 5212061 complement(3411589..3412353) 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3412353 echA17 5212061 echA17 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001284415.1 3411589 R 419947 CDS YP_001284416.1 148662893 5212062 complement(3412362..3413228) 1 NC_009525.1 hypothetical protein 3413228 5212062 MRA_3072 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284416.1 3412362 R 419947 CDS YP_001284417.1 148662894 5212063 complement(3413225..3414088) 1 NC_009525.1 ABC transporter ATP-binding protein 3414088 5212063 MRA_3073 Mycobacterium tuberculosis H37Ra ABC transporter ATP-binding protein YP_001284417.1 3413225 R 419947 CDS YP_001284418.1 148662895 5214066 complement(3414103..3415332) 1 NC_009525.1 phosphoserine phosphatase 3415332 serB2 5214066 serB2 Mycobacterium tuberculosis H37Ra phosphoserine phosphatase YP_001284418.1 3414103 R 419947 CDS YP_001284419.1 148662896 5214067 complement(3415370..3417091) 1 NC_009525.1 cytochrome c oxidase subunit I 3417091 ctaD 5214067 ctaD Mycobacterium tuberculosis H37Ra cytochrome c oxidase subunit I YP_001284419.1 3415370 R 419947 CDS YP_001284420.1 148662897 5214068 3417306..3418385 1 NC_009525.1 iron ABC transporter substrate-binding protein 3418385 fecB 5214068 fecB Mycobacterium tuberculosis H37Ra iron ABC transporter substrate-binding protein YP_001284420.1 3417306 D 419947 CDS YP_001284421.1 148662898 5214069 3418455..3419495 1 NC_009525.1 NADP-dependent alcohol dehydrogenase 3419495 adhC 5214069 adhC Mycobacterium tuberculosis H37Ra NADP-dependent alcohol dehydrogenase YP_001284421.1 3418455 D 419947 CDS YP_001284422.1 148662899 5214070 complement(3419484..3419858) 1 NC_009525.1 hypothetical protein 3419858 5214070 MRA_3078 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284422.1 3419484 R 419947 CDS YP_001284423.1 148662900 5214071 complement(3420192..3420476) 1 NC_009525.1 hypothetical protein 3420476 5214071 MRA_3079 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284423.1 3420192 R 419947 CDS YP_001284424.1 148662901 5214072 complement(3420574..3421548) 1 NC_009525.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3421548 nrdF2 5214072 nrdF2 Mycobacterium tuberculosis H37Ra ribonucleotide-diphosphate reductase subunit beta YP_001284424.1 3420574 R 419947 CDS YP_001284425.1 148662902 5214073 complement(3421679..3423253) 1 NC_009525.1 monooxygenase 3423253 5214073 MRA_3081 Mycobacterium tuberculosis H37Ra monooxygenase YP_001284425.1 3421679 R 419947 CDS YP_001284426.1 148662903 5213581 complement(3423387..3424127) 1 NC_009525.1 transcription regulator AsnC 3424127 5213581 MRA_3082 Mycobacterium tuberculosis H37Ra transcription regulator AsnC YP_001284426.1 3423387 R 419947 CDS YP_001284427.1 148662904 5213582 complement(3424255..3426336) 1 NC_009525.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3426336 nrdE 5213582 nrdE Mycobacterium tuberculosis H37Ra ribonucleotide-diphosphate reductase subunit alpha YP_001284427.1 3424255 R 419947 CDS YP_001284428.1 148662905 5213583 complement(3426402..3426854) 1 NC_009525.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3426854 nrdI 5213583 nrdI Mycobacterium tuberculosis H37Ra ribonucleotide reductase stimulatory protein YP_001284428.1 3426402 R 419947 CDS YP_001284429.1 148662906 5213584 complement(3426889..3427128) 1 NC_009525.1 glutaredoxin NrdH 3427128 nrdH 5213584 nrdH Mycobacterium tuberculosis H37Ra glutaredoxin NrdH YP_001284429.1 3426889 R 419947 CDS YP_001284430.1 148662907 5213585 complement(3427591..3428145) 1 NC_009525.1 hypothetical protein 3428145 5213585 MRA_3086 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284430.1 3427591 R 419947 CDS YP_001284431.1 148662908 5213586 3428237..3428851 1 NC_009525.1 TetR family transcriptional regulator 3428851 5213586 MRA_3087 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284431.1 3428237 D 419947 CDS YP_001284432.1 148662909 5213587 3428861..3429901 1 NC_009525.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 3429901 dinP 5213587 dinP Mycobacterium tuberculosis H37Ra DNA polymerase IV YP_001284432.1 3428861 D 419947 CDS YP_001284433.1 148662910 5213588 complement(3429955..3430818) 1 NC_009525.1 short chain dehydrogenase 3430818 5213588 MRA_3089 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284433.1 3429955 R 419947 CDS YP_001284434.1 148662911 5213589 complement(3430882..3431532) 1 NC_009525.1 TetR family transcriptional regulator 3431532 5213589 MRA_3090 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284434.1 3430882 R 419947 CDS YP_001284435.1 148662912 5214807 3431648..3433126 1 NC_009525.1 cytochrome p450 136 CYP136 3433126 cyp136 5214807 cyp136 Mycobacterium tuberculosis H37Ra cytochrome p450 136 CYP136 YP_001284435.1 3431648 D 419947 CDS YP_001284436.1 148662913 5214808 complement(3433897..3435369) 1 NC_009525.1 GntR family transcriptional regulator 3435369 5214808 MRA_3092 Mycobacterium tuberculosis H37Ra GntR family transcriptional regulator YP_001284436.1 3433897 R 419947 CDS YP_001284437.1 148662914 5214809 complement(3435418..3437583) 1 NC_009525.1 acyl-CoA dehydrogenase 3437583 fadE22 5214809 fadE22 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284437.1 3435418 R 419947 CDS YP_001284438.1 148662915 5214810 3437740..3439263 1 NC_009525.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase 3439263 ligB 5214810 ligB Mycobacterium tuberculosis H37Ra ATP-dependent DNA ligase YP_001284438.1 3437740 D 419947 CDS YP_001284439.1 148662916 5214811 3439399..3441675 1 NC_009525.1 carbon starvation protein A 3441675 cstA 5214811 cstA Mycobacterium tuberculosis H37Ra carbon starvation protein A YP_001284439.1 3439399 D 419947 CDS YP_001284440.1 148662917 5214812 3441724..3441906 1 NC_009525.1 hypothetical protein 3441906 5214812 MRA_3096 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284440.1 3441724 D 419947 CDS YP_001284441.1 148662918 5214813 complement(3441981..3442406) 1 NC_009525.1 integral membrane protein 3442406 5214813 MRA_3097 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284441.1 3441981 R 419947 CDS YP_001284442.1 148662919 5214814 3442543..3442866 1 NC_009525.1 multidrugs-transport integral membrane protein Mmr 3442866 mmr 5214814 mmr Mycobacterium tuberculosis H37Ra multidrugs-transport integral membrane protein Mmr YP_001284442.1 3442543 D 419947 CDS YP_001284443.1 148662920 5214815 3442863..3443471 1 NC_009525.1 DeoR family transcriptional regulator 3443471 5214815 MRA_3099 Mycobacterium tuberculosis H37Ra DeoR family transcriptional regulator YP_001284443.1 3442863 D 419947 CDS YP_001284444.1 148662921 5215618 3443584..3443994 1 NC_009525.1 hypothetical protein 3443994 5215618 MRA_3100 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284444.1 3443584 D 419947 CDS YP_001284445.1 148662922 5215620 complement(3444135..3445778) 1 NC_009525.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 3445778 pgmA 5215620 pgmA Mycobacterium tuberculosis H37Ra phosphoglucomutase YP_001284445.1 3444135 R 419947 CDS YP_001284446.1 148662923 5215621 3445848..3446246 1 NC_009525.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 3446246 ccrB1 5215621 ccrB1 Mycobacterium tuberculosis H37Ra camphor resistance protein CrcB YP_001284446.1 3445848 D 419947 CDS YP_001284447.1 148662924 5215622 3446243..3446623 1 NC_009525.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 3446623 ccrB2 5215622 ccrB2 Mycobacterium tuberculosis H37Ra camphor resistance protein CrcB YP_001284447.1 3446243 D 419947 CDS YP_001284448.1 148662925 5215623 3446620..3447729 1 NC_009525.1 hypothetical protein 3447729 5215623 MRA_3104 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284448.1 3446620 D 419947 CDS YP_001284449.1 148662926 5215624 complement(3447954..3448478) 1 NC_009525.1 hypothetical protein 3448478 5215624 MRA_3105 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284449.1 3447954 R 419947 CDS YP_001284450.1 148662927 5215625 complement(3448485..3448841) 1 NC_009525.1 hypothetical protein 3448841 5215625 MRA_3106 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284450.1 3448485 R 419947 CDS YP_001284451.1 148662928 5213912 3448935..3450209 1 NC_009525.1 hypothetical protein 3450209 5213912 MRA_3107 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284451.1 3448935 D 419947 CDS YP_001284452.1 148662929 5213913 complement(3450206..3451129) 1 NC_009525.1 hypothetical protein 3451129 5213913 MRA_3108 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284452.1 3450206 R 419947 CDS YP_001284453.1 148662930 5213914 3451228..3451704 1 NC_009525.1 hypothetical protein 3451704 5213914 MRA_3109 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284453.1 3451228 D 419947 CDS YP_001284454.1 148662931 5213915 3451697..3453508 1 NC_009525.1 hydrolase 3453508 5213915 MRA_3110 Mycobacterium tuberculosis H37Ra hydrolase YP_001284454.1 3451697 D 419947 CDS YP_001284455.1 148662932 5213916 3453509..3453910 1 NC_009525.1 hydroxylaminobenzene mutase 3453910 hab 5213916 hab Mycobacterium tuberculosis H37Ra hydroxylaminobenzene mutase YP_001284455.1 3453509 D 419947 CDS YP_001284456.1 148662933 5213917 complement(3453926..3454753) 1 NC_009525.1 hypothetical protein 3454753 5213917 MRA_3112 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284456.1 3453926 R 419947 CDS YP_001284457.1 148662934 5213918 complement(3454812..3458144) 1 NC_009525.1 serine/threonine protein kinase / MalT-related protein 3458144 pknK 5213918 pknK Mycobacterium tuberculosis H37Ra serine/threonine protein kinase / MalT-related protein YP_001284457.1 3454812 R 419947 CDS YP_001284458.1 148662935 5213919 3458196..3459434 1 NC_009525.1 hypothetical protein 3459434 5213919 MRA_3113A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284458.1 3458196 D 419947 CDS YP_001284459.1 148662936 5213920 complement(3459560..3460582) 1 NC_009525.1 AraC family transcriptional regulator 3460582 virS 5213920 virS Mycobacterium tuberculosis H37Ra AraC family transcriptional regulator YP_001284459.1 3459560 R 419947 CDS YP_001284460.1 148662937 5212754 3460660..3462147 1 NC_009525.1 monooxygenase 3462147 5212754 MRA_3115 Mycobacterium tuberculosis H37Ra monooxygenase YP_001284460.1 3460660 D 419947 CDS YP_001284461.1 148662938 5212755 3462153..3463079 1 NC_009525.1 acetyl-hydrolase 3463079 lipR 5212755 lipR Mycobacterium tuberculosis H37Ra acetyl-hydrolase YP_001284461.1 3462153 D 419947 CDS YP_001284462.1 148662939 5212756 3463076..3463906 1 NC_009525.1 short-chain type dehydrogenase/reductase 3463906 5212756 MRA_3117 Mycobacterium tuberculosis H37Ra short-chain type dehydrogenase/reductase YP_001284462.1 3463076 D 419947 CDS YP_001284463.1 148662940 5212757 3463937..3465043 1 NC_009525.1 zinc-type alcohol dehydrogenase AdhD 3465043 adhD 5212757 adhD Mycobacterium tuberculosis H37Ra zinc-type alcohol dehydrogenase AdhD YP_001284463.1 3463937 D 419947 CDS YP_001284464.1 148662941 5212758 3465081..3466499 1 NC_009525.1 hypothetical protein 3466499 5212758 MRA_3119 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284464.1 3465081 D 419947 CDS YP_001284465.1 148662942 5212759 3466496..3467920 1 NC_009525.1 hypothetical protein 3467920 5212759 MRA_3120 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284465.1 3466496 D 419947 CDS YP_001284466.1 148662943 5212760 3467917..3469428 1 NC_009525.1 fatty-acid--CoA ligase 3469428 fadD13 5212760 fadD13 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001284466.1 3467917 D 419947 CDS YP_001284467.1 148662944 5212761 3470367..3471254 1 NC_009525.1 hypothetical protein 3471254 5212761 MRA_3122 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284467.1 3470367 D 419947 CDS YP_001284468.1 148662945 5212762 3471272..3472963 1 NC_009525.1 hypothetical protein 3472963 5212762 MRA_3123 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284468.1 3471272 D 419947 CDS YP_001284469.1 148662946 5214266 complement(3472970..3473890) 1 NC_009525.1 integral membrane protein 3473890 5214266 MRA_3124 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284469.1 3472970 R 419947 CDS YP_001284470.1 148662947 5214267 complement(3473916..3474920) 1 NC_009525.1 oxidoreductase 3474920 5214267 MRA_3125 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284470.1 3473916 R 419947 CDS YP_001284471.1 148662948 5214268 complement(3474917..3476047) 1 NC_009525.1 hypothetical protein 3476047 5214268 MRA_3126 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284471.1 3474917 R 419947 CDS YP_001284472.1 148662949 5214269 3476129..3476605 1 NC_009525.1 transcriptional regulatory protein 3476605 5214269 MRA_3127 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001284472.1 3476129 D 419947 CDS YP_001284473.1 148662950 5214270 3476703..3477842 1 NC_009525.1 hypothetical protein 3477842 5214270 MRA_3128 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284473.1 3476703 D 419947 CDS YP_001284474.1 148662951 5214271 complement(3477934..3479247) 1 NC_009525.1 PE-PGRS family protein 3479247 5214271 MRA_3129 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284474.1 3477934 R 419947 CDS YP_001284475.1 148662952 5214272 complement(3479366..3479818) 1 NC_009525.1 hypothetical protein 3479818 5214272 MRA_3130 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284475.1 3479366 R 419947 CDS YP_001284476.1 148662953 5214274 complement(3480569..3481420) 1 NC_009525.1 hypothetical protein 3481420 5214274 MRA_3131 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284476.1 3480569 R 419947 CDS YP_001284477.1 148662954 5212763 complement(3481457..3481939) 1 NC_009525.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3481939 smpB 5212763 smpB Mycobacterium tuberculosis H37Ra SsrA-binding protein YP_001284477.1 3481457 R 419947 CDS YP_001284478.1 148662955 5212764 complement(3481942..3482835) 1 NC_009525.1 cell division protein FtsX 3482835 ftsX 5212764 ftsX Mycobacterium tuberculosis H37Ra cell division protein FtsX YP_001284478.1 3481942 R 419947 CDS YP_001284479.1 148662956 5212765 complement(3482836..3483525) 1 NC_009525.1 cell division ATP-binding protein 3483525 ftsE 5212765 ftsE Mycobacterium tuberculosis H37Ra cell division ATP-binding protein YP_001284479.1 3482836 R 419947 CDS YP_001284480.1 148662957 5212766 complement(3483569..3484006) 1 NC_009525.1 hypothetical protein 3484006 5212766 MRA_3135 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284480.1 3483569 R 419947 CDS YP_001284481.1 148662958 5212767 complement(3484008..3484934) 1 NC_009525.1 transmembrane protein 3484934 5212767 MRA_3136 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284481.1 3484008 R 419947 CDS YP_001284482.1 148662959 5212768 complement(3484924..3486060) 1 NC_009525.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 3486060 prfB 5212768 prfB Mycobacterium tuberculosis H37Ra peptide chain release factor 2 YP_001284482.1 3484924 R 419947 CDS YP_001284483.1 148662960 5212769 3486163..3487533 1 NC_009525.1 ferredoxin-NADP reductase 3487533 fprA 5212769 fprA Mycobacterium tuberculosis H37Ra ferredoxin-NADP reductase YP_001284483.1 3486163 D 419947 CDS YP_001284484.1 148662961 5212770 complement(3487534..3489117) 1 NC_009525.1 alkyldihydroxyacetonephosphate synthase AgpS 3489117 agpS 5212770 agpS Mycobacterium tuberculosis H37Ra alkyldihydroxyacetonephosphate synthase AgpS YP_001284484.1 3487534 R 419947 CDS YP_001284485.1 148662962 5212853 3489216..3489656 1 NC_009525.1 hypothetical protein 3489656 5212853 MRA_3140 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284485.1 3489216 D 419947 CDS YP_001284486.1 148662963 5212854 3489805..3490884 1 NC_009525.1 molybdenum cofactor biosynthesis protein A1 3490884 moaA1 5212854 moaA1 Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein A1 YP_001284486.1 3489805 D 419947 CDS YP_001284487.1 148662964 5212855 3490935..3491330 1 NC_009525.1 pterin-4-alpha-carbinolamine dehydratase 3491330 moaB1 5212855 moaB1 Mycobacterium tuberculosis H37Ra pterin-4-alpha-carbinolamine dehydratase YP_001284487.1 3490935 D 419947 CDS YP_001284488.1 148662965 5212856 3491327..3491839 1 NC_009525.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 3491839 moaC 5212856 moaC Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein MoaC YP_001284488.1 3491327 D 419947 CDS YP_001284489.1 148662966 5212857 3491856..3492107 1 NC_009525.1 molybdenum cofactor biosynthesis protein D1 3492107 moaD1 5212857 moaD1 Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein D1 YP_001284489.1 3491856 D 419947 CDS YP_001284490.1 148662967 5212858 3492230..3492898 1 NC_009525.1 HAD family hydrolase 3492898 5212858 MRA_3145 Mycobacterium tuberculosis H37Ra HAD family hydrolase YP_001284490.1 3492230 D 419947 CDS YP_001284491.1 148662968 5212859 3492915..3493445 1 NC_009525.1 hypothetical protein 3493445 5212859 MRA_3146 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284491.1 3492915 D 419947 CDS YP_001284492.1 148662969 5212860 3493607..3494854 1 NC_009525.1 IS1081 transposase 3494854 5212860 MRA_3147 Mycobacterium tuberculosis H37Ra IS1081 transposase YP_001284492.1 3493607 D 419947 CDS YP_001284493.1 148662970 5212861 3494932..3496101 1 NC_009525.1 molybdenum cofactor biosynthesis protein MoeB2 3496101 moeB2 5212861 moeB2 Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein MoeB2 YP_001284493.1 3494932 D 419947 CDS YP_001284494.1 148662971 5214539 3496130..3496963 1 NC_009525.1 thiosulfate sulfurtransferase CysA3 3496963 cysA3 5214539 cysA3 Mycobacterium tuberculosis H37Ra thiosulfate sulfurtransferase CysA3 YP_001284494.1 3496130 D 419947 CDS YP_001284495.1 148662972 5214540 3496965..3497267 1 NC_009525.1 hypothetical protein 3497267 sseC1-2 5214540 sseC1-2 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284495.1 3496965 D 419947 CDS YP_001284496.1 148662973 5214541 3497288..3497731 1 NC_009525.1 molybdenum cofactor biosynthesis protein E1 3497731 moaE1 5214541 moaE1 Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein E1 YP_001284496.1 3497288 D 419947 CDS YP_001284497.1 148662974 5214542 3497728..3498330 1 NC_009525.1 hypothetical protein 3498330 5214542 MRA_3152 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284497.1 3497728 D 419947 CDS YP_001284498.1 148662975 5214543 3498665..3499867 1 NC_009525.1 cytochrome p450 141 CYP141 3499867 cyp141 5214543 cyp141 Mycobacterium tuberculosis H37Ra cytochrome p450 141 CYP141 YP_001284498.1 3498665 D 419947 CDS YP_001284499.1 148662976 5214544 3500245..3500715 1 NC_009525.1 hypothetical protein 3500715 5214544 MRA_3154 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284499.1 3500245 D 419947 CDS YP_001284500.1 148662977 5214545 3500725..3501219 1 NC_009525.1 hypothetical protein 3501219 5214545 MRA_3155 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284500.1 3500725 D 419947 CDS YP_001284501.1 148662978 5214546 3501662..3502531 1 NC_009525.1 transcriptional regulatory protein 3502531 5214546 MRA_3156 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001284501.1 3501662 D 419947 CDS YP_001284502.1 148662979 5214547 complement(3502632..3503807) 1 NC_009525.1 PPE family protein 3503807 5214547 MRA_3157 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284502.1 3502632 R 419947 CDS YP_001284503.1 148662980 5212291 complement(3503964..3504278) 1 NC_009525.1 hypothetical protein 3504278 5212291 MRA_3158 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284503.1 3503964 R 419947 CDS YP_001284504.1 148662981 5212292 3504303..3505337 1 NC_009525.1 hypothetical protein 3505337 5212292 MRA_3159 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284504.1 3504303 D 419947 CDS YP_001284505.1 148662982 5212293 complement(3505756..3506337) 1 NC_009525.1 hypothetical protein 3506337 5212293 MRA_3160 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284505.1 3505756 R 419947 CDS YP_001284506.1 148662983 5212294 3506816..3507148 1 NC_009525.1 hypothetical protein 3507148 5212294 MRA_3161 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284506.1 3506816 D 419947 CDS YP_001284507.1 148662984 5212295 complement(3507131..3508522) 1 NC_009525.1 hypothetical protein 3508522 5212295 MRA_3162 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284507.1 3507131 R 419947 CDS YP_001284508.1 148662985 5212296 3508707..3509705 1 NC_009525.1 hypothetical protein 3509705 5212296 MRA_3163 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284508.1 3508707 D 419947 CDS YP_001284509.1 148662986 5212297 complement(3509685..3511421) 1 NC_009525.1 two component sensor histidine kinase DevS 3511421 devS 5212297 devS Mycobacterium tuberculosis H37Ra two component sensor histidine kinase DevS YP_001284509.1 3509685 R 419947 CDS YP_001284510.1 148662987 5212298 complement(3511418..3512071) 1 NC_009525.1 two component transcriptional regulatory protein DevR 3512071 devR 5212298 devR Mycobacterium tuberculosis H37Ra two component transcriptional regulatory protein DevR YP_001284510.1 3511418 R 419947 CDS YP_001284511.1 148662988 5212299 complement(3512099..3512905) 1 NC_009525.1 hypothetical protein 3512905 5212299 MRA_3166 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284511.1 3512099 R 419947 CDS YP_001284512.1 148662989 5212274 3513490..3513888 1 NC_009525.1 PPE family protein 3513888 5212274 MRA_3167 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284512.1 3513490 D 419947 CDS YP_001284513.1 148662990 5212275 3513950..3515092 1 NC_009525.1 PPE family protein 3515092 5212275 MRA_3168 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284513.1 3513950 D 419947 CDS YP_001284514.1 148662991 5212276 complement(3515101..3515415) 1 NC_009525.1 hypothetical protein 3515415 5212276 MRA_3169 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284514.1 3515101 R 419947 CDS YP_001284515.1 148662992 5212277 3515549..3516331 1 NC_009525.1 monophosphatase 3516331 5212277 MRA_3170 Mycobacterium tuberculosis H37Ra monophosphatase YP_001284515.1 3515549 D 419947 CDS YP_001284516.1 148662993 5212278 3516351..3517439 1 NC_009525.1 pyruvate formate lyase-activating enzyme 3517439 pflA 5212278 pflA Mycobacterium tuberculosis H37Ra pyruvate formate lyase-activating enzyme YP_001284516.1 3516351 D 419947 CDS YP_001284517.1 148662994 5212279 3517519..3518925 1 NC_009525.1 acyl-CoA dehydrogenase 3518925 fadE24 5212279 fadE24 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284517.1 3517519 D 419947 CDS YP_001284518.1 148662995 5212280 3518946..3520151 1 NC_009525.1 acyl-CoA dehydrogenase 3520151 fadE23 5212280 fadE23 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284518.1 3518946 D 419947 CDS YP_001284519.1 148662996 5212281 3520251..3521222 1 NC_009525.1 NADPH quinone oxidoreductase FadB4 3521222 fadB4 5212281 fadB4 Mycobacterium tuberculosis H37Ra NADPH quinone oxidoreductase FadB4 YP_001284519.1 3520251 D 419947 CDS YP_001284520.1 148662997 5212282 complement(3521274..3521702) 1 NC_009525.1 hypothetical protein 3521702 5212282 MRA_3175 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284520.1 3521274 R 419947 CDS YP_001284521.1 148662998 5213751 3521810..3522211 1 NC_009525.1 hypothetical protein 3522211 5213751 MRA_3176 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284521.1 3521810 D 419947 CDS YP_001284522.1 148662999 5213752 complement(3522244..3523473) 1 NC_009525.1 PPE family protein 3523473 5213752 MRA_3177 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284522.1 3522244 R 419947 CDS YP_001284523.1 148663000 5213753 3523838..3524224 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 3524224 nuoA 5213753 nuoA Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit A YP_001284523.1 3523838 D 419947 CDS YP_001284524.1 148663001 5213754 3524233..3524787 1 NC_009525.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 3524787 nuoB 5213754 nuoB Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit B YP_001284524.1 3524233 D 419947 CDS YP_001284525.1 148663002 5213755 3524784..3525494 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 3525494 nuoC 5213755 nuoC Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit C YP_001284525.1 3524784 D 419947 CDS YP_001284526.1 148663003 5213756 3525494..3526816 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 3526816 nuoD 5213756 nuoD Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit D YP_001284526.1 3525494 D 419947 CDS YP_001284527.1 148663004 5213757 3526813..3527571 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 3527571 nuoE 5213757 nuoE Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit E YP_001284527.1 3526813 D 419947 CDS YP_001284528.1 148663005 5213758 3527568..3528905 1 NC_009525.1 NADH dehydrogenase subunit F 3528905 nuoF 5213758 nuoF Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit F YP_001284528.1 3527568 D 419947 CDS YP_001284529.1 148663006 5213759 3528902..3531322 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 3531322 nuoG 5213759 nuoG Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit G YP_001284529.1 3528902 D 419947 CDS YP_001284530.1 148663007 5213760 3531438..3532670 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 3532670 nuoH 5213760 nuoH Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit H YP_001284530.1 3531438 D 419947 CDS YP_001284531.1 148663008 5213761 3532663..3533298 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 3533298 nuoI 5213761 nuoI Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit I YP_001284531.1 3532663 D 419947 CDS YP_001284532.1 148663009 5213762 3533295..3534083 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 3534083 nuoJ 5213762 nuoJ Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit J YP_001284532.1 3533295 D 419947 CDS YP_001284533.1 148663010 5213763 3534080..3534379 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 3534379 nuoK 5213763 nuoK Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit K YP_001284533.1 3534080 D 419947 CDS YP_001284534.1 148663011 5213764 3534390..3536291 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 3536291 nuoL 5213764 nuoL Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit L YP_001284534.1 3534390 D 419947 CDS YP_001284535.1 148663012 5213765 3536288..3537949 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 3537949 nuoM 5213765 nuoM Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit M YP_001284535.1 3536288 D 419947 CDS YP_001284536.1 148663013 5213766 3537946..3539541 1 NC_009525.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 3539541 nuoN 5213766 nuoN Mycobacterium tuberculosis H37Ra NADH dehydrogenase subunit N YP_001284536.1 3537946 D 419947 CDS YP_001284537.1 148663014 5213767 complement(3539547..3541319) 1 NC_009525.1 PPE family protein 3541319 5213767 MRA_3192 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284537.1 3539547 R 419947 CDS YP_001284538.1 148663015 5213768 complement(3541494..3542135) 1 NC_009525.1 TetR family transcriptional regulator 3542135 5213768 MRA_3193 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284538.1 3541494 R 419947 CDS YP_001284539.1 148663016 5212506 complement(3542146..3543294) 1 NC_009525.1 Rieske 2Fe-2S family protein 3543294 5212506 MRA_3194 Mycobacterium tuberculosis H37Ra Rieske 2Fe-2S family protein YP_001284539.1 3542146 R 419947 CDS YP_001284540.1 148663017 5212507 complement(3543364..3543801) 1 NC_009525.1 integral membrane protein 3543801 5212507 MRA_3195 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284540.1 3543364 R 419947 CDS YP_001284541.1 148663018 5212508 complement(3543798..3545069) 1 NC_009525.1 hypothetical protein 3545069 5212508 MRA_3196 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284541.1 3543798 R 419947 CDS YP_001284542.1 148663019 5212509 complement(3545099..3546061) 1 NC_009525.1 methanol dehydrogenase transcriptional regulatory protein MoxR3 3546061 moxR3 5212509 moxR3 Mycobacterium tuberculosis H37Ra methanol dehydrogenase transcriptional regulatory protein MoxR3 YP_001284542.1 3545099 R 419947 CDS YP_001284543.1 148663020 5212510 complement(3546069..3546551) 1 NC_009525.1 hypothetical protein 3546551 5212510 MRA_3198 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284543.1 3546069 R 419947 CDS YP_001284544.1 148663021 5212511 complement(3546548..3547507) 1 NC_009525.1 hypothetical protein 3547507 5212511 MRA_3199 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284544.1 3546548 R 419947 CDS YP_001284545.1 148663022 5212512 complement(3547587..3548213) 1 NC_009525.1 TetR family transcriptional regulator 3548213 5212512 MRA_3200 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284545.1 3547587 R 419947 CDS YP_001284546.1 148663023 5212513 3548258..3549394 1 NC_009525.1 hypothetical protein 3549394 5212513 MRA_3201 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284546.1 3548258 D 419947 CDS YP_001284547.1 148663024 5212514 3549394..3550518 1 NC_009525.1 hypothetical protein 3550518 5212514 MRA_3202 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284547.1 3549394 D 419947 CDS YP_001284548.1 148663025 5214302 3550661..3552007 1 NC_009525.1 flavin-containing amine oxidase 3552007 aofH 5214302 aofH Mycobacterium tuberculosis H37Ra flavin-containing amine oxidase YP_001284548.1 3550661 D 419947 CDS YP_001284549.1 148663026 5214303 complement(3552002..3552901) 1 NC_009525.1 non-heme haloperoxidase Hpx 3552901 hpx 5214303 hpx Mycobacterium tuberculosis H37Ra non-heme haloperoxidase Hpx YP_001284549.1 3552002 R 419947 CDS YP_001284550.1 148663027 5214304 complement(3553038..3553520) 1 NC_009525.1 hypothetical protein 3553520 5214304 MRA_3205 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284550.1 3553038 R 419947 CDS YP_001284551.1 148663028 5214305 complement(3553599..3554201) 1 NC_009525.1 TetR/AcrR-family transcriptional regulator 3554201 5214305 MRA_3206 Mycobacterium tuberculosis H37Ra TetR/AcrR-family transcriptional regulator YP_001284551.1 3553599 R 419947 CDS YP_001284552.1 148663029 5214306 3554294..3555001 1 NC_009525.1 short chain dehydrogenase 3555001 5214306 MRA_3207 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284552.1 3554294 D 419947 CDS YP_001284553.1 148663030 5214307 3555016..3556503 1 NC_009525.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 3556503 5214307 MRA_3208 Mycobacterium tuberculosis H37Ra amidase YP_001284553.1 3555016 D 419947 CDS YP_001284554.1 148663031 5214308 complement(3556500..3557456) 1 NC_009525.1 epoxide hydrolase 3557456 mesT 5214308 mesT Mycobacterium tuberculosis H37Ra epoxide hydrolase YP_001284554.1 3556500 R 419947 CDS YP_001284555.1 148663032 5214309 3557603..3558463 1 NC_009525.1 non-haem peroxidase; peroxidase 3558463 5214309 MRA_3210 Mycobacterium tuberculosis H37Ra peroxidase YP_001284555.1 3557603 D 419947 CDS YP_001284556.1 148663033 5214310 3558594..3558953 1 NC_009525.1 hypothetical protein 3558953 5214310 MRA_3211 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284556.1 3558594 D 419947 CDS YP_001284557.1 148663034 5213498 3559190..3559486 1 NC_009525.1 hypothetical protein 3559486 5213498 MRA_3212 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284557.1 3559190 D 419947 CDS YP_001284558.1 148663035 5213499 3559774..3561063 1 NC_009525.1 hypothetical protein 3561063 5213499 MRA_3213 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284558.1 3559774 D 419947 CDS YP_001284559.1 148663036 5213500 complement(3561410..3561844) 1 NC_009525.1 hypothetical protein 3561844 5213500 MRA_3214 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284559.1 3561410 R 419947 CDS YP_001284560.1 148663037 5213501 complement(3561847..3562299) 1 NC_009525.1 hypothetical protein 3562299 5213501 MRA_3215 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284560.1 3561847 R 419947 CDS YP_001284561.1 148663038 5213502 3562530..3562874 1 NC_009525.1 hypothetical protein 3562874 5213502 MRA_3216 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284561.1 3562530 D 419947 CDS YP_001284562.1 148663039 5213503 3562871..3563200 1 NC_009525.1 transcriptional regulatory protein 3563200 5213503 MRA_3217 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001284562.1 3562871 D 419947 CDS YP_001284563.1 148663040 5213504 3563562..3563888 1 NC_009525.1 IS6110 hypothetical protein 3563888 5213504 MRA_3218 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001284563.1 3563562 D 419947 CDS YP_001284564.1 148663041 5213505 3563939..3564823 1 NC_009525.1 IS6110 transposase 3564823 5213505 MRA_3219 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001284564.1 3563939 D 419947 CDS YP_001284565.1 148663042 5213506 3565096..3565443 1 NC_009525.1 hypothetical protein 3565443 5213506 MRA_3220 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284565.1 3565096 D 419947 CDS YP_001284566.1 148663043 5213285 3565440..3566060 1 NC_009525.1 hypothetical protein 3566060 5213285 MRA_3221 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284566.1 3565440 D 419947 CDS YP_001284567.1 148663044 5213286 complement(3566220..3567485) 1 NC_009525.1 hypothetical protein 3567485 5213286 MRA_3222 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284567.1 3566220 R 419947 CDS YP_001284568.1 148663045 5213287 3567653..3567862 1 NC_009525.1 hypothetical protein 3567862 5213287 MRA_3223 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284568.1 3567653 D 419947 CDS YP_001284569.1 148663046 5213288 complement(3568109..3569143) 1 NC_009525.1 transposase 3569143 5213288 MRA_3224 Mycobacterium tuberculosis H37Ra transposase YP_001284569.1 3568109 R 419947 CDS YP_001284570.1 148663047 5213289 complement(3569427..3569636) 1 NC_009525.1 hypothetical protein 3569636 5213289 MRA_3225 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284570.1 3569427 R 419947 CDS YP_001284571.1 148663048 5213291 3570346..3570807 1 NC_009525.1 hypothetical protein 3570807 5213291 MRA_3226 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284571.1 3570346 D 419947 CDS YP_001284572.1 148663049 5213292 complement(3570977..3573955) 1 NC_009525.1 hypothetical protein 3573955 5213292 MRA_3227 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284572.1 3570977 R 419947 CDS YP_001284573.1 148663050 5215082 complement(3574047..3575069) 1 NC_009525.1 hypothetical protein 3575069 5215082 MRA_3228 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284573.1 3574047 R 419947 CDS YP_001284574.1 148663051 5215083 3575147..3576565 1 NC_009525.1 hypothetical protein 3576565 5215083 MRA_3229 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284574.1 3575147 D 419947 CDS YP_001284575.1 148663052 5215084 3576571..3577470 1 NC_009525.1 hypothetical protein 3577470 5215084 MRA_3230 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284575.1 3576571 D 419947 CDS YP_001284576.1 148663053 5215085 complement(3577479..3577679) 1 NC_009525.1 hypothetical protein 3577679 5215085 MRA_3231 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284576.1 3577479 R 419947 CDS YP_001284577.1 148663054 5215086 3577807..3579150 1 NC_009525.1 ABC transporter ATP-binding protein 3579150 5215086 MRA_3232 Mycobacterium tuberculosis H37Ra ABC transporter ATP-binding protein YP_001284577.1 3577807 D 419947 CDS YP_001284578.1 148663055 5215087 complement(3579184..3579462) 1 NC_009525.1 transcriptional regulatory protein whib-like WhiB7 3579462 whiB7 5215087 whiB7 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein whib-like WhiB7 YP_001284578.1 3579184 R 419947 CDS YP_001284579.1 148663056 5215088 complement(3579892..3581994) 1 NC_009525.1 ATP dependent DNA helicase UvrD2 3581994 uvrD2 5215088 uvrD2 Mycobacterium tuberculosis H37Ra ATP dependent DNA helicase UvrD2 YP_001284579.1 3579892 R 419947 CDS YP_001284580.1 148663057 5215089 3582118..3582372 1 NC_009525.1 glutaredoxin protein 3582372 5215089 MRA_3235 Mycobacterium tuberculosis H37Ra glutaredoxin protein YP_001284580.1 3582118 D 419947 CDS YP_001284581.1 148663058 5215090 complement(3582385..3583326) 1 NC_009525.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 3583326 nudC 5215090 nudC Mycobacterium tuberculosis H37Ra NADH pyrophosphatase YP_001284581.1 3582385 R 419947 CDS YP_001284582.1 148663059 5215551 complement(3583385..3584452) 1 NC_009525.1 transmembrane cation transporter 3584452 5215551 MRA_3237 Mycobacterium tuberculosis H37Ra transmembrane cation transporter YP_001284582.1 3583385 R 419947 CDS YP_001284583.1 148663060 5215552 complement(3584514..3587819) 1 NC_009525.1 UvrD/REP helicase 3587819 5215552 MRA_3238 Mycobacterium tuberculosis H37Ra UvrD/REP helicase YP_001284583.1 3584514 R 419947 CDS YP_001284584.1 148663061 5215553 complement(3587816..3590983) 1 NC_009525.1 UvrD/REP helicase 3590983 5215553 MRA_3239 Mycobacterium tuberculosis H37Ra UvrD/REP helicase YP_001284584.1 3587816 R 419947 CDS YP_001284585.1 148663062 5215554 3591069..3591278 1 NC_009525.1 hypothetical protein 3591278 5215554 MRA_3240 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284585.1 3591069 D 419947 CDS YP_001284586.1 148663063 5215555 3591420..3592094 1 NC_009525.1 lipase LipV 3592094 lipV 5215555 lipV Mycobacterium tuberculosis H37Ra lipase LipV YP_001284586.1 3591420 D 419947 CDS YP_001284587.1 148663064 5215556 3592097..3592402 1 NC_009525.1 6-O-methylguanine DNA methyltransferase 3592402 5215556 MRA_3242 Mycobacterium tuberculosis H37Ra 6-O-methylguanine DNA methyltransferase YP_001284587.1 3592097 D 419947 CDS YP_001284588.1 148663065 5215557 complement(3592409..3593287) 1 NC_009525.1 hypothetical protein 3593287 5215557 MRA_3243 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284588.1 3592409 R 419947 CDS YP_001284589.1 148663066 5215558 complement(3593314..3594492) 1 NC_009525.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; molybdopterin biosynthesis-like protein MoeZ 3594492 moeB1 5215558 moeB1 Mycobacterium tuberculosis H37Ra molybdopterin biosynthesis-like protein MoeZ YP_001284589.1 3593314 R 419947 CDS YP_001284590.1 148663067 5215559 complement(3594583..3595440) 1 NC_009525.1 hypothetical protein 3595440 5215559 MRA_3245 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284590.1 3594583 R 419947 CDS YP_001284591.1 148663068 5213928 3595786..3596472 1 NC_009525.1 TetR family transcriptional regulator 3596472 5213928 MRA_3246 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284591.1 3595786 D 419947 CDS YP_001284592.1 148663069 5213929 complement(3596459..3596731) 1 NC_009525.1 hypothetical protein 3596731 5213929 MRA_3247 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284592.1 3596459 R 419947 CDS YP_001284593.1 148663070 5213930 3597056..3597616 1 NC_009525.1 hypothetical protein 3597616 5213930 MRA_3248 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284593.1 3597056 D 419947 CDS YP_001284594.1 148663071 5213931 complement(3597626..3598321) 1 NC_009525.1 hypothetical protein 3598321 5213931 MRA_3249 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284594.1 3597626 R 419947 CDS YP_001284595.1 148663072 5213932 3598580..3600163 1 NC_009525.1 ATP-dependent RNA helicase RhlE 3600163 rhlE 5213932 rhlE Mycobacterium tuberculosis H37Ra ATP-dependent RNA helicase RhlE YP_001284595.1 3598580 D 419947 CDS YP_001284596.1 148663073 5213933 3600176..3601399 1 NC_009525.1 hypothetical protein 3601399 5213933 MRA_3251 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284596.1 3600176 D 419947 CDS YP_001284597.1 148663074 5213934 complement(3601475..3602275) 1 NC_009525.1 soj/parA-related protein 3602275 5213934 MRA_3252 Mycobacterium tuberculosis H37Ra soj/parA-related protein YP_001284597.1 3601475 R 419947 CDS YP_001284598.1 148663075 5213935 3602429..3603040 1 NC_009525.1 forms a homodimer in Mycobacterium tuberculosis; belongs to the dPGM superfamily; acid phosphatase 3603040 gpm2 5213935 gpm2 Mycobacterium tuberculosis H37Ra acid phosphatase YP_001284598.1 3602429 D 419947 CDS YP_001284599.1 148663076 5213936 3603037..3604155 1 NC_009525.1 isochorismate synthase EntC 3604155 entC 5213936 entC Mycobacterium tuberculosis H37Ra isochorismate synthase EntC YP_001284599.1 3603037 D 419947 CDS YP_001284600.1 148663077 5214142 3604303..3604635 1 NC_009525.1 acetyltransferase 3604635 5214142 MRA_3255 Mycobacterium tuberculosis H37Ra acetyltransferase YP_001284600.1 3604303 D 419947 CDS YP_001284601.1 148663078 5214143 complement(3604587..3605018) 1 NC_009525.1 integral membrane protein 3605018 5214143 MRA_3256 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284601.1 3604587 R 419947 CDS YP_001284602.1 148663079 5214144 3605251..3606216 1 NC_009525.1 hypothetical protein 3606216 5214144 MRA_3257 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284602.1 3605251 D 419947 CDS YP_001284603.1 148663080 5214145 3606496..3606750 1 NC_009525.1 transcriptional regulatory protein whib-like WhiB1 3606750 whiB1 5214145 whiB1 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein whib-like WhiB1 YP_001284603.1 3606496 D 419947 CDS YP_001284604.1 148663081 5214146 complement(3606812..3608317) 1 NC_009525.1 two component sensor kinase 3608317 5214146 MRA_3259 Mycobacterium tuberculosis H37Ra two component sensor kinase YP_001284604.1 3606812 R 419947 CDS YP_001284605.1 148663082 5214147 complement(3608334..3608549) 1 NC_009525.1 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3608549 5214147 MRA_3260 Mycobacterium tuberculosis H37Ra acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_001284605.1 3608334 R 419947 CDS YP_001284606.1 148663083 5214148 complement(3608834..3609139) 1 NC_009525.1 anti-sigma factor 3609139 5214148 MRA_3261 Mycobacterium tuberculosis H37Ra anti-sigma factor YP_001284606.1 3608834 R 419947 CDS YP_001284607.1 148663084 5214149 complement(3609136..3609687) 1 NC_009525.1 hypothetical protein 3609687 5214149 MRA_3262 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284607.1 3609136 R 419947 CDS YP_001284608.1 148663085 5214150 complement(3609684..3610334) 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 3610334 sigH 5214150 sigH Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor RpoE YP_001284608.1 3609684 R 419947 CDS YP_001284609.1 148663086 5214234 3610634..3611482 1 NC_009525.1 short chain dehydrogenase 3611482 5214234 MRA_3264 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284609.1 3610634 D 419947 CDS YP_001284610.1 148663087 5214235 complement(3611578..3611805) 1 NC_009525.1 hypothetical protein 3611805 5214235 MRA_3265 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284610.1 3611578 R 419947 CDS YP_001284611.1 148663088 5214236 complement(3611799..3613223) 1 NC_009525.1 transferase 3613223 5214236 MRA_3266 Mycobacterium tuberculosis H37Ra transferase YP_001284611.1 3611799 R 419947 CDS YP_001284612.1 148663089 5214237 complement(3613347..3614105) 1 NC_009525.1 hypothetical protein 3614105 5214237 MRA_3267 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284612.1 3613347 R 419947 CDS YP_001284613.1 148663090 5214238 3614160..3615512 1 NC_009525.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 3615512 aroA 5214238 aroA Mycobacterium tuberculosis H37Ra 3-phosphoshikimate 1-carboxyvinyltransferase YP_001284613.1 3614160 D 419947 CDS YP_001284614.1 148663091 5214239 3615509..3616501 1 NC_009525.1 hypothetical protein 3616501 5214239 MRA_3269 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284614.1 3615509 D 419947 CDS YP_001284615.1 148663092 5214240 complement(3616534..3617817) 1 NC_009525.1 linoleoyl-CoA desaturase 3617817 5214240 MRA_3270 Mycobacterium tuberculosis H37Ra linoleoyl-CoA desaturase YP_001284615.1 3616534 R 419947 CDS YP_001284616.1 148663093 5214241 complement(3617895..3619037) 1 NC_009525.1 oxidoreductase 3619037 5214241 MRA_3271 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284616.1 3617895 R 419947 CDS YP_001284617.1 148663094 5214242 complement(3619147..3619656) 1 NC_009525.1 hypothetical protein 3619656 5214242 MRA_3272 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284617.1 3619147 R 419947 CDS YP_001284618.1 148663095 5215261 complement(3619653..3620540) 1 NC_009525.1 RNA polymerase sigma factor 3620540 pvdS 5215261 pvdS Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor YP_001284618.1 3619653 R 419947 CDS YP_001284619.1 148663096 5215262 complement(3620564..3621154) 1 NC_009525.1 hypothetical protein 3621154 5215262 MRA_3274 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284619.1 3620564 R 419947 CDS YP_001284620.1 148663097 5215263 complement(3621157..3621972) 1 NC_009525.1 hypothetical protein 3621972 5215263 MRA_3275 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284620.1 3621157 R 419947 CDS YP_001284621.1 148663098 5215264 3622083..3622724 1 NC_009525.1 hypothetical protein 3622724 5215264 MRA_3276 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284621.1 3622083 D 419947 CDS YP_001284622.1 148663099 5215265 complement(3622742..3623899) 1 NC_009525.1 cation/proton antiporter 3623899 5215265 MRA_3277 Mycobacterium tuberculosis H37Ra cation/proton antiporter YP_001284622.1 3622742 R 419947 CDS YP_001284623.1 148663100 5215266 complement(3623904..3624386) 1 NC_009525.1 hypothetical protein 3624386 5215266 MRA_3278 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284623.1 3623904 R 419947 CDS YP_001284624.1 148663101 5215267 complement(3624447..3625181) 1 NC_009525.1 integral membrane protein 3625181 5215267 MRA_3279 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284624.1 3624447 R 419947 CDS YP_001284625.1 148663102 5215268 complement(3625240..3628386) 1 NC_009525.1 integral membrane transport protein 3628386 5215268 MRA_3280 Mycobacterium tuberculosis H37Ra integral membrane transport protein YP_001284625.1 3625240 R 419947 CDS YP_001284626.1 148663103 5215269 complement(3628465..3631314) 1 NC_009525.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 3631314 secA1 5215269 secA1 Mycobacterium tuberculosis H37Ra preprotein translocase subunit SecA YP_001284626.1 3628465 R 419947 CDS YP_001284627.1 148663104 5213541 complement(3631393..3632037) 1 NC_009525.1 S30AE family protein 3632037 5213541 MRA_3282 Mycobacterium tuberculosis H37Ra S30AE family protein YP_001284627.1 3631393 R 419947 CDS YP_001284628.1 148663105 5213542 complement(3632353..3632994) 1 NC_009525.1 hypothetical protein 3632994 5213542 MRA_3283 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284628.1 3632353 R 419947 CDS YP_001284629.1 148663106 5213543 complement(3633032..3633874) 1 NC_009525.1 hypothetical protein 3633874 5213543 MRA_3284 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284629.1 3633032 R 419947 CDS YP_001284630.1 148663107 5213544 complement(3633942..3635693) 1 NC_009525.1 lipoprotein LpqB 3635693 lpqB 5213544 lpqB Mycobacterium tuberculosis H37Ra lipoprotein LpqB YP_001284630.1 3633942 R 419947 CDS YP_001284631.1 148663108 5213545 complement(3635693..3637396) 1 NC_009525.1 two component sensory transduction histidine kinase MtrB 3637396 mtrB 5213545 mtrB Mycobacterium tuberculosis H37Ra two component sensory transduction histidine kinase MtrB YP_001284631.1 3635693 R 419947 CDS YP_001284632.1 148663109 5213546 complement(3637446..3638132) 1 NC_009525.1 two component sensory transduction transcriptional regulatory protein MtrA 3638132 mtrA 5213546 mtrA Mycobacterium tuberculosis H37Ra two component sensory transduction transcriptional regulatory protein MtrA YP_001284632.1 3637446 R 419947 CDS YP_001284633.1 148663110 5213547 complement(3638202..3638846) 1 NC_009525.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 3638846 tmk 5213547 tmk Mycobacterium tuberculosis H37Ra thymidylate kinase YP_001284633.1 3638202 R 419947 CDS YP_001284634.1 148663111 5213548 complement(3638943..3640430) 1 NC_009525.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 3640430 sahH 5213548 sahH Mycobacterium tuberculosis H37Ra S-adenosyl-L-homocysteine hydrolase YP_001284634.1 3638943 R 419947 CDS YP_001284635.1 148663112 5213549 complement(3640535..3641170) 1 NC_009525.1 MarR family transcriptional regulator 3641170 5213549 MRA_3290 Mycobacterium tuberculosis H37Ra MarR family transcriptional regulator YP_001284635.1 3640535 R 419947 CDS YP_001284636.1 148663113 5213107 complement(3641167..3641349) 1 NC_009525.1 rubredoxin RubB 3641349 rubB 5213107 rubB Mycobacterium tuberculosis H37Ra rubredoxin RubB YP_001284636.1 3641167 R 419947 CDS YP_001284637.1 148663114 5213108 complement(3641354..3641521) 1 NC_009525.1 rubredoxin RubA 3641521 rubA 5213108 rubA Mycobacterium tuberculosis H37Ra rubredoxin RubA YP_001284637.1 3641354 R 419947 CDS YP_001284638.1 148663115 5213109 complement(3641521..3642771) 1 NC_009525.1 transmembrane alkane 1-monooxygenase AlkB 3642771 alkB 5213109 alkB Mycobacterium tuberculosis H37Ra transmembrane alkane 1-monooxygenase AlkB YP_001284638.1 3641521 R 419947 CDS YP_001284639.1 148663116 5213110 complement(3642880..3644367) 1 NC_009525.1 amino acid permease 3644367 5213110 MRA_3294 Mycobacterium tuberculosis H37Ra amino acid permease YP_001284639.1 3642880 R 419947 CDS YP_001284640.1 148663117 5213111 3644458..3645846 1 NC_009525.1 hypothetical protein 3645846 5213111 MRA_3295 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284640.1 3644458 D 419947 CDS YP_001284641.1 148663118 5213112 complement(3645824..3647050) 1 NC_009525.1 mannose-6-phosphate isomerase 3647050 manA 5213112 manA Mycobacterium tuberculosis H37Ra mannose-6-phosphate isomerase YP_001284641.1 3645824 R 419947 CDS YP_001284642.1 148663119 5213113 complement(3647058..3648098) 1 NC_009525.1 hypothetical protein 3648098 5213113 MRA_3297 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284642.1 3647058 R 419947 CDS YP_001284643.1 148663120 5213114 complement(3648095..3649492) 1 NC_009525.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase/phosphoglucomutase 3649492 manB 5213114 manB Mycobacterium tuberculosis H37Ra phosphomannomutase/phosphoglucomutase YP_001284643.1 3648095 R 419947 CDS YP_001284644.1 148663121 5213115 complement(3649594..3650085) 1 NC_009525.1 hypothetical protein 3650085 5213115 MRA_3299 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284644.1 3649594 R 419947 CDS YP_001284645.1 148663122 5213301 3650208..3650627 1 NC_009525.1 hypothetical protein 3650627 5213301 MRA_3300 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284645.1 3650208 D 419947 CDS YP_001284646.1 148663123 5213302 complement(3650655..3650924) 1 NC_009525.1 WhiB-related protein 3650924 whiB2 5213302 whiB2 Mycobacterium tuberculosis H37Ra WhiB-related protein YP_001284646.1 3650655 R 419947 CDS YP_001284647.1 148663124 5213303 3651326..3652321 1 NC_009525.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); LPPG:FO 2-phospho-L-lactate transferase 3652321 fbiA 5213303 fbiA Mycobacterium tuberculosis H37Ra LPPG:FO 2-phospho-L-lactate transferase YP_001284647.1 3651326 D 419947 CDS YP_001284648.1 148663125 5213304 3652318..3653664 1 NC_009525.1 catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); F420-0--gamma-glutamyl ligase 3653664 fbiB 5213304 fbiB Mycobacterium tuberculosis H37Ra F420-0--gamma-glutamyl ligase YP_001284648.1 3652318 D 419947 CDS YP_001284649.1 148663126 5213305 3653960..3655621 1 NC_009525.1 DNA methylase 3655621 5213305 MRA_3304 Mycobacterium tuberculosis H37Ra DNA methylase YP_001284649.1 3653960 D 419947 CDS YP_001284650.1 148663127 5213306 complement(3655681..3656760) 1 NC_009525.1 mannose-1-phosphate guanylyltransferase 3656760 manB 5213306 manB Mycobacterium tuberculosis H37Ra mannose-1-phosphate guanylyltransferase YP_001284650.1 3655681 R 419947 CDS YP_001284651.1 148663128 5213307 complement(3656762..3657667) 1 NC_009525.1 dTDP-RHA:A-D-GlcNAc-diphosphoryl polyprenol,A-3-L-rhamnosyltransferase WbbL1 3657667 wbbL1 5213307 wbbL1 Mycobacterium tuberculosis H37Ra dTDP-RHA:A-D-GlcNAc-diphosphoryl polyprenol,A-3-L-rhamnosyltransferase WbbL1 YP_001284651.1 3656762 R 419947 CDS YP_001284652.1 148663129 5213308 complement(3657678..3658592) 1 NC_009525.1 dTDP-4-dehydrorhamnose reductase 3658592 rmlD 5213308 rmlD Mycobacterium tuberculosis H37Ra dTDP-4-dehydrorhamnose reductase YP_001284652.1 3657678 R 419947 CDS YP_001284653.1 148663130 5213309 3658668..3660164 1 NC_009525.1 CpsA-related protein; hypothetical protein 3660164 5213309 MRA_3308 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284653.1 3658668 D 419947 CDS YP_001284654.1 148663131 5213808 3660203..3660892 1 NC_009525.1 hypothetical protein 3660892 5213808 MRA_3309 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284654.1 3660203 D 419947 CDS YP_001284655.1 148663132 5213809 3661017..3661298 1 NC_009525.1 hypothetical protein 3661298 5213809 MRA_3310 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284655.1 3661017 D 419947 CDS YP_001284656.1 148663133 5213810 3661309..3663465 1 NC_009525.1 metal cation transporting P-type ATPase CtpC 3663465 ctpC 5213810 ctpC Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpC YP_001284656.1 3661309 D 419947 CDS YP_001284657.1 148663134 5213811 complement(3663462..3664130) 1 NC_009525.1 integral membrane protein 3664130 5213811 MRA_3312 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284657.1 3663462 R 419947 CDS YP_001284658.1 148663135 5213812 3664231..3665415 1 NC_009525.1 hypothetical protein 3665415 5213812 MRA_3313 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284658.1 3664231 D 419947 CDS YP_001284659.1 148663136 5213813 3665420..3667714 1 NC_009525.1 sulfate transporter/carbonic anhydrase 3667714 5213813 MRA_3314 Mycobacterium tuberculosis H37Ra sulfate transporter/carbonic anhydrase YP_001284659.1 3665420 D 419947 CDS YP_001284660.1 148663137 5213814 complement(3667703..3668872) 1 NC_009525.1 acyl-CoA dehydrogenase 3668872 fadE25 5213814 fadE25 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284660.1 3667703 R 419947 CDS YP_001284661.1 148663138 5213815 complement(3668897..3669421) 1 NC_009525.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 3669421 purE 5213815 purE Mycobacterium tuberculosis H37Ra phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001284661.1 3668897 R 419947 CDS YP_001284662.1 148663139 5213816 complement(3669418..3670707) 1 NC_009525.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 3670707 purK 5213816 purK Mycobacterium tuberculosis H37Ra phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001284662.1 3669418 R 419947 CDS YP_001284663.1 148663140 5214737 3670661..3671479 1 NC_009525.1 transmembrane protein 3671479 5214737 MRA_3318 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284663.1 3670661 D 419947 CDS YP_001284664.1 148663141 5214738 complement(3671434..3671952) 1 NC_009525.1 transmembrane protein 3671952 5214738 MRA_3319 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284664.1 3671434 R 419947 CDS YP_001284665.1 148663142 5214739 complement(3671995..3672795) 1 NC_009525.1 biotin operon repressor/biotin--(acetyl-coa-carboxylase) synthetase; bifunctional protein BirA 3672795 birA 5214739 birA Mycobacterium tuberculosis H37Ra bifunctional protein BirA YP_001284665.1 3671995 R 419947 CDS YP_001284666.1 148663143 5214740 3672845..3674491 1 NC_009525.1 propionyl-CoA carboxylase subunit beta 3674491 accD5 5214740 accD5 Mycobacterium tuberculosis H37Ra propionyl-CoA carboxylase subunit beta YP_001284666.1 3672845 D 419947 CDS YP_001284667.1 148663144 5214741 3674472..3675005 1 NC_009525.1 hypothetical protein 3675005 5214741 MRA_3322 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284667.1 3674472 D 419947 CDS YP_001284668.1 148663145 5214742 3675002..3675670 1 NC_009525.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3675670 maf 5214742 maf Mycobacterium tuberculosis H37Ra Maf-like protein YP_001284668.1 3675002 D 419947 CDS YP_001284669.1 148663146 5214743 3675711..3676604 1 NC_009525.1 thiosulfate sulfurtransferase SseA 3676604 sseA 5214743 sseA Mycobacterium tuberculosis H37Ra thiosulfate sulfurtransferase SseA YP_001284669.1 3675711 D 419947 CDS YP_001284670.1 148663147 5214744 3676601..3677032 1 NC_009525.1 hypothetical protein 3677032 5214744 MRA_3325 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284670.1 3676601 D 419947 CDS YP_001284671.1 148663148 5214745 3677140..3678942 1 NC_009525.1 AccA3; bifunctional protein; acetyl-/propionyl-coenzyme A carboxylase alpha chain biotin carboxylase/biotin carboxyl carrier protein 3678942 accA3 5214745 accA3 Mycobacterium tuberculosis H37Ra acetyl-/propionyl-coenzyme A carboxylase alpha chain biotin carboxylase/biotin carboxyl carrier protein YP_001284671.1 3677140 D 419947 CDS YP_001284672.1 148663149 5213235 complement(3678952..3679737) 1 NC_009525.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is a general stress response regulator; expressed in stationary phase and under nitrogen depletion and cold shock; RNA polymerase sigma factor SigF 3679737 sigF 5213235 sigF Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigF YP_001284672.1 3678952 R 419947 CDS YP_001284673.1 148663150 5213236 complement(3679734..3680171) 1 NC_009525.1 anti-sigma factor RsbW 3680171 rsbW 5213236 rsbW Mycobacterium tuberculosis H37Ra anti-sigma factor RsbW YP_001284673.1 3679734 R 419947 CDS YP_001284674.1 148663151 5213237 complement(3680369..3680782) 1 NC_009525.1 protein UsfY 3680782 usfY 5213237 usfY Mycobacterium tuberculosis H37Ra protein UsfY YP_001284674.1 3680369 R 419947 CDS YP_001284675.1 148663152 5213238 complement(3680817..3681194) 1 NC_009525.1 transmembrane protein 3681194 5213238 MRA_3330 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284675.1 3680817 R 419947 CDS YP_001284676.1 148663153 5213239 complement(3681228..3682577) 1 NC_009525.1 catalyzes the formation of 2-aminoadipate 6-semiladehyde and glutamate from lysine and 2-oxoglutarate; L-lysine aminotransferase 3682577 lat 5213239 lat Mycobacterium tuberculosis H37Ra L-lysine aminotransferase YP_001284676.1 3681228 R 419947 CDS YP_001284677.1 148663154 5213240 complement(3682628..3683080) 1 NC_009525.1 leucine-responsive regulatory protein 3683080 5213240 MRA_3332 Mycobacterium tuberculosis H37Ra leucine-responsive regulatory protein YP_001284677.1 3682628 R 419947 CDS YP_001284678.1 148663155 5213241 3683111..3684358 1 NC_009525.1 hypothetical protein 3684358 5213241 MRA_3333 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284678.1 3683111 D 419947 CDS YP_001284679.1 148663156 5213242 3684385..3685869 1 NC_009525.1 piperideine-6-carboxylic acid dehydrogenase 3685869 pcd 5213242 pcd Mycobacterium tuberculosis H37Ra piperideine-6-carboxylic acid dehydrogenase YP_001284679.1 3684385 D 419947 CDS YP_001284680.1 148663157 5213243 complement(3685969..3686778) 1 NC_009525.1 hypothetical protein 3686778 5213243 MRA_3335 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284680.1 3685969 R 419947 CDS YP_001284681.1 148663158 5213620 3686849..3687514 1 NC_009525.1 TetR family transcriptional regulator 3687514 5213620 MRA_3336 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284681.1 3686849 D 419947 CDS YP_001284682.1 148663159 5213621 3687558..3692099 1 NC_009525.1 ATP-dependent helicase Lhr 3692099 lhr 5213621 lhr Mycobacterium tuberculosis H37Ra ATP-dependent helicase Lhr YP_001284682.1 3687558 D 419947 CDS YP_001284683.1 148663160 5213622 3692103..3692870 1 NC_009525.1 endonuclease VIII 3692870 nei 5213622 nei Mycobacterium tuberculosis H37Ra endonuclease VIII YP_001284683.1 3692103 D 419947 CDS YP_001284684.1 148663161 5213623 complement(3692893..3693807) 1 NC_009525.1 esterase lipoprotein LpqC 3693807 lpqC 5213623 lpqC Mycobacterium tuberculosis H37Ra esterase lipoprotein LpqC YP_001284684.1 3692893 R 419947 CDS YP_001284685.1 148663162 5213624 complement(3693834..3696746) 1 NC_009525.1 aryl-sulfate sulphohydrolase; arylsulfatase AtsB 3696746 atsB 5213624 atsB Mycobacterium tuberculosis H37Ra arylsulfatase AtsB YP_001284685.1 3693834 R 419947 CDS YP_001284686.1 148663163 5213625 complement(3696766..3697683) 1 NC_009525.1 hypothetical protein 3697683 5213625 MRA_3341 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284686.1 3696766 R 419947 CDS YP_001284687.1 148663164 5213626 complement(3697695..3698360) 1 NC_009525.1 phosphate transport system regulator PhoU-related protein 3698360 phoY1 5213626 phoY1 Mycobacterium tuberculosis H37Ra phosphate transport system regulator PhoU-related protein YP_001284687.1 3697695 R 419947 CDS YP_001284688.1 148663165 5213627 complement(3698468..3700225) 1 NC_009525.1 glycerol-3-phosphate dehydrogenase Glpd2 3700225 glpD2 5213627 glpD2 Mycobacterium tuberculosis H37Ra glycerol-3-phosphate dehydrogenase Glpd2 YP_001284688.1 3698468 R 419947 CDS YP_001284689.1 148663166 5213628 complement(3700240..3701721) 1 NC_009525.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase 3701721 lpdA 5213628 lpdA Mycobacterium tuberculosis H37Ra flavoprotein disulfide reductase YP_001284689.1 3700240 R 419947 CDS YP_001284690.1 148663167 5212939 3701982..3702461 1 NC_009525.1 hypothetical protein 3702461 5212939 MRA_3345 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284690.1 3701982 D 419947 CDS YP_001284691.1 148663168 5212940 complement(3702480..3703649) 1 NC_009525.1 N-acyl-L-amino acid amidohydrolase AmiA1 3703649 amiA1 5212940 amiA1 Mycobacterium tuberculosis H37Ra N-acyl-L-amino acid amidohydrolase AmiA1 YP_001284691.1 3702480 R 419947 CDS YP_001284692.1 148663169 5212941 complement(3703646..3704830) 1 NC_009525.1 amidase AmiB1 3704830 amiB1 5212941 amiB1 Mycobacterium tuberculosis H37Ra amidase AmiB1 YP_001284692.1 3703646 R 419947 CDS YP_001284693.1 148663170 5212942 3704895..3705701 1 NC_009525.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 3705701 deoD 5212942 deoD Mycobacterium tuberculosis H37Ra purine nucleoside phosphorylase YP_001284693.1 3704895 D 419947 CDS YP_001284694.1 148663171 5212943 3705705..3707309 1 NC_009525.1 phosphomannomutase PmmB 3707309 pmmB 5212943 pmmB Mycobacterium tuberculosis H37Ra phosphomannomutase PmmB YP_001284694.1 3705705 D 419947 CDS YP_001284695.1 148663172 5212944 complement(3707311..3707934) 1 NC_009525.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 3707934 upp 5212944 upp Mycobacterium tuberculosis H37Ra uracil phosphoribosyltransferase YP_001284695.1 3707311 R 419947 CDS YP_001284696.1 148663173 5212945 3708039..3708938 1 NC_009525.1 acid phosphatase 3708938 5212945 MRA_3351 Mycobacterium tuberculosis H37Ra acid phosphatase YP_001284696.1 3708039 D 419947 CDS YP_001284697.1 148663174 5212946 3708962..3710224 1 NC_009525.1 hypothetical protein 3710224 5212946 MRA_3352 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284697.1 3708962 D 419947 CDS YP_001284698.1 148663175 5212947 complement(3710245..3711171) 1 NC_009525.1 hypothetical protein 3711171 5212947 MRA_3353 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284698.1 3710245 R 419947 CDS YP_001284699.1 148663176 5212803 complement(3711546..3711857) 1 NC_009525.1 secreted protein antigen 3711857 5212803 MRA_3354 Mycobacterium tuberculosis H37Ra secreted protein antigen YP_001284699.1 3711546 R 419947 CDS YP_001284700.1 148663177 5212804 complement(3711928..3713025) 1 NC_009525.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 3713025 add 5212804 add Mycobacterium tuberculosis H37Ra adenosine deaminase YP_001284700.1 3711928 R 419947 CDS YP_001284701.1 148663178 5212805 complement(3713025..3714308) 1 NC_009525.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 3714308 deoA 5212805 deoA Mycobacterium tuberculosis H37Ra thymidine phosphorylase YP_001284701.1 3713025 R 419947 CDS YP_001284702.1 148663179 5212806 complement(3714305..3714706) 1 NC_009525.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 3714706 cdd 5212806 cdd Mycobacterium tuberculosis H37Ra cytidine deaminase YP_001284702.1 3714305 R 419947 CDS YP_001284703.1 148663180 5212807 3714943..3715281 1 NC_009525.1 succinate dehydrogenase cytochrome B-556 subunit SdhC 3715281 sdhC 5212807 sdhC Mycobacterium tuberculosis H37Ra succinate dehydrogenase cytochrome B-556 subunit SdhC YP_001284703.1 3714943 D 419947 CDS YP_001284704.1 148663181 5212808 3715278..3715712 1 NC_009525.1 succinate dehydrogenase hydrophobic membrane anchor subunit SdhD 3715712 sdhD 5212808 sdhD Mycobacterium tuberculosis H37Ra succinate dehydrogenase hydrophobic membrane anchor subunit SdhD YP_001284704.1 3715278 D 419947 CDS YP_001284705.1 148663182 5212809 3715841..3717613 1 NC_009525.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 3717613 sdhA 5212809 sdhA Mycobacterium tuberculosis H37Ra succinate dehydrogenase flavoprotein subunit YP_001284705.1 3715841 D 419947 CDS YP_001284706.1 148663183 5212810 3717613..3718404 1 NC_009525.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 3718404 sdhB 5212810 sdhB Mycobacterium tuberculosis H37Ra succinate dehydrogenase iron-sulfur subunit YP_001284706.1 3717613 D 419947 CDS YP_001284707.1 148663184 5212811 complement(3718483..3718911) 1 NC_009525.1 hypothetical protein 3718911 5212811 MRA_3362 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284707.1 3718483 R 419947 CDS YP_001284708.1 148663185 5211649 complement(3718915..3719157) 1 NC_009525.1 hypothetical protein 3719157 5211649 MRA_3363 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284708.1 3718915 R 419947 CDS YP_001284709.1 148663186 5211650 complement(3719279..3719893) 1 NC_009525.1 methyltransferase 3719893 5211650 MRA_3364 Mycobacterium tuberculosis H37Ra methyltransferase YP_001284709.1 3719279 R 419947 CDS YP_001284710.1 148663187 5211651 complement(3719890..3720555) 1 NC_009525.1 MoaD-MoaE fusion protein MoaX 3720555 moaX 5211651 moaX Mycobacterium tuberculosis H37Ra MoaD-MoaE fusion protein MoaX YP_001284710.1 3719890 R 419947 CDS YP_001284711.1 148663188 5211652 complement(3720556..3721089) 1 NC_009525.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 3721089 moaC 5211652 moaC Mycobacterium tuberculosis H37Ra molybdenum cofactor biosynthesis protein MoaC YP_001284711.1 3720556 R 419947 CDS YP_001284712.1 148663189 5211653 3721274..3721600 1 NC_009525.1 IS6110 hypothetical protein 3721600 5211653 MRA_3367 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001284712.1 3721274 D 419947 CDS YP_001284713.1 148663190 5211654 3721651..3722535 1 NC_009525.1 IS6110 transposase 3722535 5211654 MRA_3368 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001284713.1 3721651 D 419947 CDS YP_001284714.1 148663191 5211655 3722590..3724302 1 NC_009525.1 IS1547 transposase 3724302 5211655 MRA_3369 Mycobacterium tuberculosis H37Ra IS1547 transposase YP_001284714.1 3722590 D 419947 CDS YP_001284715.1 148663192 5211656 complement(3724235..3725173) 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigJ 3725173 sigJ 5211656 sigJ Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigJ YP_001284715.1 3724235 R 419947 CDS YP_001284716.1 148663193 5211657 3725233..3726549 1 NC_009525.1 hypothetical protein 3726549 5211657 MRA_3371 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284716.1 3725233 D 419947 CDS YP_001284717.1 148663194 5215329 3726618..3727835 1 NC_009525.1 penicillin-binding protein DacB1 3727835 dacB1 5215329 dacB1 Mycobacterium tuberculosis H37Ra penicillin-binding protein DacB1 YP_001284717.1 3726618 D 419947 CDS YP_001284718.1 148663195 5215330 3727931..3729439 1 NC_009525.1 sugar-transport integral membrane protein SugI 3729439 sugI 5215330 sugI Mycobacterium tuberculosis H37Ra sugar-transport integral membrane protein SugI YP_001284718.1 3727931 D 419947 CDS YP_001284719.1 148663196 5215331 3729436..3730587 1 NC_009525.1 N-acetylglucosamine-6-phosphate deacetylase 3730587 nagA 5215331 nagA Mycobacterium tuberculosis H37Ra N-acetylglucosamine-6-phosphate deacetylase YP_001284719.1 3729436 D 419947 CDS YP_001284720.1 148663197 5215332 complement(3730778..3731623) 1 NC_009525.1 hypothetical protein 3731623 5215332 MRA_3375 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284720.1 3730778 R 419947 CDS YP_001284721.1 148663198 5215333 3732098..3732538 1 NC_009525.1 MerR family transcriptional regulator 3732538 5215333 MRA_3376 Mycobacterium tuberculosis H37Ra MerR family transcriptional regulator YP_001284721.1 3732098 D 419947 CDS YP_001284722.1 148663199 5215334 complement(3732572..3733441) 1 NC_009525.1 integral membrane protein 3733441 5215334 MRA_3377 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284722.1 3732572 R 419947 CDS YP_001284723.1 148663200 5215335 complement(3733462..3734472) 1 NC_009525.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3734472 trpS 5215335 trpS Mycobacterium tuberculosis H37Ra tryptophanyl-tRNA synthetase YP_001284723.1 3733462 R 419947 CDS YP_001284724.1 148663201 5215336 3734745..3735389 1 NC_009525.1 hypothetical protein 3735389 5215336 MRA_3379 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284724.1 3734745 D 419947 CDS YP_001284725.1 148663202 5215337 complement(3735456..3736685) 1 NC_009525.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 3736685 icd1 5215337 icd1 Mycobacterium tuberculosis H37Ra isocitrate dehydrogenase YP_001284725.1 3735456 R 419947 CDS YP_001284726.1 148663203 5211947 3736968..3738317 1 NC_009525.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 3738317 metC 5211947 metC Mycobacterium tuberculosis H37Ra O-acetylhomoserine aminocarboxypropyltransferase YP_001284726.1 3736968 D 419947 CDS YP_001284727.1 148663204 5211948 3738329..3739468 1 NC_009525.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 3739468 metX 5211948 metX Mycobacterium tuberculosis H37Ra homoserine O-acetyltransferase YP_001284727.1 3738329 D 419947 CDS YP_001284728.1 148663205 5211949 3739465..3740196 1 NC_009525.1 methyltransferase 3740196 5211949 MRA_3383 Mycobacterium tuberculosis H37Ra methyltransferase YP_001284728.1 3739465 D 419947 CDS YP_001284729.1 148663206 5211950 complement(3740205..3746048) 1 NC_009525.1 PPE family protein 3746048 5211950 MRA_3384 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284729.1 3740205 R 419947 CDS YP_001284730.1 148663207 5211951 complement(3747271..3751887) 1 NC_009525.1 PE-PGRS family protein 3751887 5211951 MRA_3385 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284730.1 3747271 R 419947 CDS YP_001284731.1 148663208 5211952 complement(3752311..3752568) 1 NC_009525.1 hypothetical protein 3752568 5211952 MRA_3386 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284731.1 3752311 R 419947 CDS YP_001284732.1 148663209 5211953 complement(3752824..3762261) 1 NC_009525.1 PPE family protein 3762261 5211953 MRA_3387 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284732.1 3752824 R 419947 CDS YP_001284733.1 148663210 5211954 3762878..3763369 1 NC_009525.1 transposase 3763369 5211954 MRA_3388 Mycobacterium tuberculosis H37Ra transposase YP_001284733.1 3762878 D 419947 CDS YP_001284734.1 148663211 5211955 complement(3763406..3764146) 1 NC_009525.1 transposase 3764146 5211955 MRA_3389 Mycobacterium tuberculosis H37Ra transposase YP_001284734.1 3763406 R 419947 CDS YP_001284735.1 148663212 5213659 complement(3765065..3776089) 1 NC_009525.1 PPE family protein 3776089 5213659 MRA_3390 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284735.1 3765065 R 419947 CDS YP_001284736.1 148663213 5213660 complement(3776109..3776417) 1 NC_009525.1 PPE family protein 3776417 5213660 MRA_3391 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284736.1 3776109 R 419947 CDS YP_001284737.1 148663214 5213661 complement(3776460..3777254) 1 NC_009525.1 hypothetical protein 3777254 5213661 MRA_3392 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284737.1 3776460 R 419947 CDS YP_001284738.1 148663215 5213662 complement(3777336..3777707) 1 NC_009525.1 oxidoreductase 3777707 5213662 MRA_3393 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284738.1 3777336 R 419947 CDS YP_001284739.1 148663216 5213663 complement(3777850..3778110) 1 NC_009525.1 hypothetical protein 3778110 5213663 MRA_3393A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284739.1 3777850 R 419947 CDS YP_001284740.1 148663217 5213664 3778225..3778614 1 NC_009525.1 hypothetical protein 3778614 5213664 MRA_3394 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284740.1 3778225 D 419947 CDS YP_001284741.1 148663218 5213665 complement(3778628..3778921) 1 NC_009525.1 hypothetical protein 3778921 5213665 MRA_3395 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284741.1 3778628 R 419947 CDS YP_001284742.1 148663219 5213666 complement(3778918..3779763) 1 NC_009525.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3779763 folD 5213666 folD Mycobacterium tuberculosis H37Ra bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001284742.1 3778918 R 419947 CDS YP_001284743.1 148663220 5213667 3779887..3780162 1 NC_009525.1 hypothetical protein 3780162 5213667 MRA_3397 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284743.1 3779887 D 419947 CDS YP_001284744.1 148663221 5213969 3780159..3780416 1 NC_009525.1 hypothetical protein 3780416 5213969 MRA_3398 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284744.1 3780159 D 419947 CDS YP_001284745.1 148663222 5213970 3780458..3781648 1 NC_009525.1 oxidoreductase 3781648 5213970 MRA_3399 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284745.1 3780458 D 419947 CDS YP_001284746.1 148663223 5213971 3781765..3782133 1 NC_009525.1 hypothetical protein 3782133 5213971 MRA_3400 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284746.1 3781765 D 419947 CDS YP_001284747.1 148663224 5213972 complement(3782130..3782681) 1 NC_009525.1 hypothetical protein 3782681 5213972 MRA_3401 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284747.1 3782130 R 419947 CDS YP_001284748.1 148663225 5213973 complement(3782688..3783269) 1 NC_009525.1 ATP/GTP-binding protein 3783269 5213973 MRA_3402 Mycobacterium tuberculosis H37Ra ATP/GTP-binding protein YP_001284748.1 3782688 R 419947 CDS YP_001284749.1 148663226 5213974 complement(3783250..3783618) 1 NC_009525.1 hypothetical protein 3783618 5213974 MRA_3403 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284749.1 3783250 R 419947 CDS YP_001284750.1 148663227 5213975 complement(3783596..3783988) 1 NC_009525.1 hypothetical protein 3783988 5213975 MRA_3404 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284750.1 3783596 R 419947 CDS YP_001284751.1 148663228 5213976 complement(3783985..3786615) 1 NC_009525.1 hypothetical protein 3786615 5213976 MRA_3405 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284751.1 3783985 R 419947 CDS YP_001284752.1 148663229 5213977 3786851..3787315 1 NC_009525.1 tRNA/rRNA methylase SpoU 3787315 spoU 5213977 spoU Mycobacterium tuberculosis H37Ra tRNA/rRNA methylase SpoU YP_001284752.1 3786851 D 419947 CDS YP_001284753.1 148663230 5212497 3787682..3789457 1 NC_009525.1 PE-PGRS family protein 3789457 5212497 MRA_3407 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284753.1 3787682 D 419947 CDS YP_001284754.1 148663231 5212498 complement(3789458..3790102) 1 NC_009525.1 oxidoreductase 3790102 5212498 MRA_3408 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284754.1 3789458 R 419947 CDS YP_001284755.1 148663232 5212499 3790101..3790535 1 NC_009525.1 hypothetical protein 3790535 5212499 MRA_3409 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284755.1 3790101 D 419947 CDS YP_001284756.1 148663233 5212500 complement(3790624..3793863) 1 NC_009525.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase 3793863 dnaE2 5212500 dnaE2 Mycobacterium tuberculosis H37Ra error-prone DNA polymerase YP_001284756.1 3790624 R 419947 CDS YP_001284757.1 148663234 5212501 3794055..3795395 1 NC_009525.1 hypothetical protein 3795395 5212501 MRA_3411 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284757.1 3794055 D 419947 CDS YP_001284758.1 148663235 5212502 3795437..3796612 1 NC_009525.1 trehalose-phosphatase 3796612 otsB2 5212502 otsB2 Mycobacterium tuberculosis H37Ra trehalose-phosphatase YP_001284758.1 3795437 D 419947 CDS YP_001284759.1 148663236 5212503 3796849..3797490 1 NC_009525.1 enoyl-CoA hydratase 3797490 echA18 5212503 echA18 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001284759.1 3796849 D 419947 CDS YP_001284760.1 148663237 5212504 3797491..3797739 1 NC_009525.1 enoyl-CoA hydratase 3797739 echA18.1 5212504 echA18.1 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001284760.1 3797491 D 419947 CDS YP_001284761.1 148663238 5212505 3797744..3799171 1 NC_009525.1 amidase 3799171 amiD 5212505 amiD Mycobacterium tuberculosis H37Ra amidase YP_001284761.1 3797744 D 419947 CDS YP_001284762.1 148663239 5214816 3799279..3799932 1 NC_009525.1 hypothetical protein 3799932 5214816 MRA_3416 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284762.1 3799279 D 419947 CDS YP_001284763.1 148663240 5214817 complement(3799971..3801476) 1 NC_009525.1 cyclase 3801476 5214817 MRA_3417 Mycobacterium tuberculosis H37Ra cyclase YP_001284763.1 3799971 R 419947 CDS YP_001284764.1 148663241 5214818 complement(3801481..3802371) 1 NC_009525.1 hypothetical protein 3802371 5214818 MRA_3418 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284764.1 3801481 R 419947 CDS YP_001284765.1 148663242 5214819 complement(3802380..3803990) 1 NC_009525.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3803990 dxs2 5214819 dxs2 Mycobacterium tuberculosis H37Ra 1-deoxy-D-xylulose-5-phosphate synthase YP_001284765.1 3802380 R 419947 CDS YP_001284766.1 148663243 5214820 complement(3804223..3805107) 1 NC_009525.1 IS6110 transposase 3805107 5214820 MRA_3420 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001284766.1 3804223 R 419947 CDS YP_001284767.1 148663244 5214821 complement(3805158..3805484) 1 NC_009525.1 IS6110 hypothetical protein 3805484 5214821 MRA_3421 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001284767.1 3805158 R 419947 CDS YP_001284768.1 148663245 5214822 complement(3805571..3806560) 1 NC_009525.1 lytB-related protein LytB1 3806560 lytB1 5214822 lytB1 Mycobacterium tuberculosis H37Ra lytB-related protein LytB1 YP_001284768.1 3805571 R 419947 CDS YP_001284769.1 148663246 5214823 complement(3806560..3807612) 1 NC_009525.1 polyprenyl synthetase IdsB 3807612 idsB 5214823 idsB Mycobacterium tuberculosis H37Ra polyprenyl synthetase IdsB YP_001284769.1 3806560 R 419947 CDS YP_001284770.1 148663247 5214824 complement(3808366..3808758) 1 NC_009525.1 hypothetical protein 3808758 5214824 MRA_3424 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284770.1 3808366 R 419947 CDS YP_001284771.1 148663248 5214653 complement(3808758..3809066) 1 NC_009525.1 hypothetical protein 3809066 5214653 MRA_3425 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284771.1 3808758 R 419947 CDS YP_001284772.1 148663249 5214654 3809215..3809919 1 NC_009525.1 transposase 3809919 5214654 MRA_3426 Mycobacterium tuberculosis H37Ra transposase YP_001284772.1 3809215 D 419947 CDS YP_001284773.1 148663250 5214655 3809909..3810586 1 NC_009525.1 transposase 3810586 5214655 MRA_3427 Mycobacterium tuberculosis H37Ra transposase YP_001284773.1 3809909 D 419947 CDS YP_001284774.1 148663251 5214656 complement(3810668..3813469) 1 NC_009525.1 hypothetical protein 3813469 5214656 MRA_3428A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284774.1 3810668 R 419947 CDS YP_001284775.1 148663252 5214657 3810776..3812524 1 NC_009525.1 PE-PGRS family protein 3812524 5214657 MRA_3428 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284775.1 3810776 D 419947 CDS YP_001284776.1 148663253 5214658 3813543..3814253 1 NC_009525.1 lipoprotein LpqD 3814253 lpqD 5214658 lpqD Mycobacterium tuberculosis H37Ra lipoprotein LpqD YP_001284776.1 3813543 D 419947 CDS YP_001284777.1 148663254 5214659 3814299..3816251 1 NC_009525.1 short chain dehydrogenase 3816251 acrA1 5214659 acrA1 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284777.1 3814299 D 419947 CDS YP_001284778.1 148663255 5214660 complement(3816252..3817115) 1 NC_009525.1 cyclopropane-fatty-acyl-phospholipid synthase 1 3817115 cmaA1 5214660 cmaA1 Mycobacterium tuberculosis H37Ra cyclopropane-fatty-acyl-phospholipid synthase 1 YP_001284778.1 3816252 R 419947 CDS YP_001284779.1 148663256 5214661 3817139..3818065 1 NC_009525.1 inosine-uridine preferring nucleoside hydrolase 3818065 iunH 5214661 iunH Mycobacterium tuberculosis H37Ra inosine-uridine preferring nucleoside hydrolase YP_001284779.1 3817139 D 419947 CDS YP_001284780.1 148663257 5215512 complement(3818120..3819703) 1 NC_009525.1 hypothetical protein 3819703 5215512 MRA_3433 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284780.1 3818120 R 419947 CDS YP_001284781.1 148663258 5215513 complement(3819700..3820314) 1 NC_009525.1 hypothetical protein 3820314 5215513 MRA_3434 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284781.1 3819700 R 419947 CDS YP_001284782.1 148663259 5215514 3820397..3821023 1 NC_009525.1 hypothetical protein 3821023 5215514 MRA_3435 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284782.1 3820397 D 419947 CDS YP_001284783.1 148663260 5215515 complement(3821179..3822756) 1 NC_009525.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 3822756 guaA 5215515 guaA Mycobacterium tuberculosis H37Ra GMP synthase YP_001284783.1 3821179 R 419947 CDS YP_001284784.1 148663261 5215516 complement(3822768..3823676) 1 NC_009525.1 phytoene synthase 3823676 phyA 5215516 phyA Mycobacterium tuberculosis H37Ra phytoene synthase YP_001284784.1 3822768 R 419947 CDS YP_001284785.1 148663262 5215517 complement(3823705..3824784) 1 NC_009525.1 multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 3824784 idsA1 5215517 idsA1 Mycobacterium tuberculosis H37Ra multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 YP_001284785.1 3823705 R 419947 CDS YP_001284786.1 148663263 5215518 3824807..3825853 1 NC_009525.1 hypothetical protein 3825853 5215518 MRA_3439 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284786.1 3824807 D 419947 CDS YP_001284787.1 148663264 5215519 3825917..3826705 1 NC_009525.1 HAD family hydrolase 3826705 5215519 MRA_3440 Mycobacterium tuberculosis H37Ra HAD family hydrolase YP_001284787.1 3825917 D 419947 CDS YP_001284788.1 148663265 5215520 3826720..3829080 1 NC_009525.1 hypothetical protein 3829080 5215520 MRA_3441 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284788.1 3826720 D 419947 CDS YP_001284789.1 148663266 5213416 complement(3829331..3830569) 1 NC_009525.1 hypothetical protein 3830569 5213416 MRA_3442 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284789.1 3829331 R 419947 CDS YP_001284790.1 148663267 5213417 complement(3830940..3832541) 1 NC_009525.1 hypothetical protein 3832541 5213417 MRA_3443 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284790.1 3830940 R 419947 CDS YP_001284791.1 148663268 5213418 complement(3832558..3833262) 1 NC_009525.1 hypothetical protein 3833262 5213418 MRA_3444 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284791.1 3832558 R 419947 CDS YP_001284792.1 148663269 5213419 complement(3833380..3833946) 1 NC_009525.1 transcriptional regulatory protein 3833946 5213419 MRA_3445 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001284792.1 3833380 R 419947 CDS YP_001284793.1 148663270 5213420 3834008..3834895 1 NC_009525.1 dioxygenase 3834895 5213420 MRA_3446 Mycobacterium tuberculosis H37Ra dioxygenase YP_001284793.1 3834008 D 419947 CDS YP_001284794.1 148663271 5213421 3834930..3835229 1 NC_009525.1 hypothetical protein 3835229 5213421 MRA_3447 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284794.1 3834930 D 419947 CDS YP_001284795.1 148663272 5213422 3835226..3835636 1 NC_009525.1 hypothetical protein 3835636 5213422 MRA_3448 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284795.1 3835226 D 419947 CDS YP_001284796.1 148663273 5213423 complement(3835669..3837405) 1 NC_009525.1 cholesterol-o2 oxidoreductase; cholesterol oxidase precursor ChoD 3837405 choD 5213423 choD Mycobacterium tuberculosis H37Ra cholesterol oxidase precursor ChoD YP_001284796.1 3835669 R 419947 CDS YP_001284797.1 148663274 5213424 complement(3837461..3838588) 1 NC_009525.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 3838588 guaB3 5213424 guaB3 Mycobacterium tuberculosis H37Ra inosine 5-monophosphate dehydrogenase YP_001284797.1 3837461 R 419947 CDS YP_001284798.1 148663275 5211730 complement(3838608..3840197) 1 NC_009525.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 3840197 guaB2 5211730 guaB2 Mycobacterium tuberculosis H37Ra inosine 5'-monophosphate dehydrogenase YP_001284798.1 3838608 R 419947 CDS YP_001284799.1 148663276 5211731 3840404..3840814 1 NC_009525.1 hypothetical protein 3840814 5211731 MRA_3452 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284799.1 3840404 D 419947 CDS YP_001284800.1 148663277 5211732 complement(3840824..3841723) 1 NC_009525.1 hypothetical protein 3841723 5211732 MRA_3453 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284800.1 3840824 R 419947 CDS YP_001284801.1 148663278 5211733 complement(3841716..3842354) 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase; RNA polymerase sigma factor SigD 3842354 sigD 5211733 sigD Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigD YP_001284801.1 3841716 R 419947 CDS YP_001284802.1 148663279 5211734 complement(3842372..3843199) 1 NC_009525.1 hypothetical protein 3843199 5211734 MRA_3455 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284802.1 3842372 R 419947 CDS YP_001284803.1 148663280 5211735 3843570..3843878 1 NC_009525.1 transcriptional regulatory protein whib-like WhiB3 3843878 whiB3 5211735 whiB3 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein whib-like WhiB3 YP_001284803.1 3843570 D 419947 CDS YP_001284804.1 148663281 5211736 complement(3843950..3845569) 1 NC_009525.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; molecular chaperone GroEL 3845569 groEL 5211736 groEL Mycobacterium tuberculosis H37Ra molecular chaperone GroEL YP_001284804.1 3843950 R 419947 CDS YP_001284805.1 148663282 5211737 complement(3845664..3845966) 1 NC_009525.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 3845966 groES 5211737 groES Mycobacterium tuberculosis H37Ra co-chaperonin GroES YP_001284805.1 3845664 R 419947 CDS YP_001284806.1 148663283 5211738 complement(3846233..3847267) 1 NC_009525.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3847267 gcp 5211738 gcp Mycobacterium tuberculosis H37Ra DNA-binding/iron metalloprotein/AP endonuclease YP_001284806.1 3846233 R 419947 CDS YP_001284807.1 148663284 5213089 complement(3847264..3847740) 1 NC_009525.1 ribosomal-protein-alanine acetyltransferase RimI 3847740 rimI 5213089 rimI Mycobacterium tuberculosis H37Ra ribosomal-protein-alanine acetyltransferase RimI YP_001284807.1 3847264 R 419947 CDS YP_001284808.1 148663285 5213090 complement(3847737..3848372) 1 NC_009525.1 hypothetical protein 3848372 5213090 MRA_3461 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284808.1 3847737 R 419947 CDS YP_001284809.1 148663286 5213091 complement(3848369..3848875) 1 NC_009525.1 hypothetical protein 3848875 5213091 MRA_3462 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284809.1 3848369 R 419947 CDS YP_001284810.1 148663287 5213092 complement(3848872..3850098) 1 NC_009525.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 3850098 alr 5213092 alr Mycobacterium tuberculosis H37Ra alanine racemase YP_001284810.1 3848872 R 419947 CDS YP_001284811.1 148663288 5213093 complement(3850392..3850754) 1 NC_009525.1 hypothetical protein 3850754 5213093 MRA_3464 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284811.1 3850392 R 419947 CDS YP_001284812.1 148663289 5213094 3850917..3851447 1 NC_009525.1 PPE family protein 3851447 5213094 MRA_3465 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284812.1 3850917 D 419947 CDS YP_001284813.1 148663290 5213095 3851714..3852412 1 NC_009525.1 PPE family protein 3852412 5213095 MRA_3466 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284813.1 3851714 D 419947 CDS YP_001284814.1 148663291 5213096 complement(3852563..3853318) 1 NC_009525.1 ISMt2 transposase B 3853318 5213096 MRA_3467 Mycobacterium tuberculosis H37Ra ISMt2 transposase B YP_001284814.1 3852563 R 419947 CDS YP_001284815.1 148663292 5213097 complement(3853416..3854648) 1 NC_009525.1 ISMt2 transposase A 3854648 5213097 MRA_3468 Mycobacterium tuberculosis H37Ra ISMt2 transposase A YP_001284815.1 3853416 R 419947 CDS YP_001284816.1 148663293 5214982 3855843..3856379 1 NC_009525.1 PPE family protein 3856379 5214982 MRA_3469 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284816.1 3855843 D 419947 CDS YP_001284817.1 148663294 5214983 complement(3856320..3857483) 1 NC_009525.1 IS1141-like transposase 3857483 5214983 MRA_3470 Mycobacterium tuberculosis H37Ra IS1141-like transposase YP_001284817.1 3856320 R 419947 CDS YP_001284818.1 148663295 5214984 complement(3857702..3857944) 1 NC_009525.1 hypothetical protein 3857944 5214984 MRA_3471 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284818.1 3857702 R 419947 CDS YP_001284819.1 148663296 5214985 complement(3857972..3858817) 1 NC_009525.1 transposase 3858817 5214985 MRA_3472 Mycobacterium tuberculosis H37Ra transposase YP_001284819.1 3857972 R 419947 CDS YP_001284820.1 148663297 5214986 complement(3859050..3860432) 1 NC_009525.1 glutamate decarboxylase 3860432 gadB 5214986 gadB Mycobacterium tuberculosis H37Ra glutamate decarboxylase YP_001284820.1 3859050 R 419947 CDS YP_001284821.1 148663298 5214987 complement(3860470..3861891) 1 NC_009525.1 hypothetical protein 3861891 5214987 MRA_3474 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284821.1 3860470 R 419947 CDS YP_001284822.1 148663299 5214988 complement(3861893..3862606) 1 NC_009525.1 transmembrane protein 3862606 5214988 MRA_3475 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284822.1 3861893 R 419947 CDS YP_001284823.1 148663300 5214989 complement(3862617..3863471) 1 NC_009525.1 hypothetical protein 3863471 5214989 MRA_3476 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284823.1 3862617 R 419947 CDS YP_001284824.1 148663301 5214990 complement(3863693..3865567) 1 NC_009525.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 3865567 glmS 5214990 glmS Mycobacterium tuberculosis H37Ra glucosamine--fructose-6-phosphate aminotransferase YP_001284824.1 3863693 R 419947 CDS YP_001284825.1 148663302 5215360 3865589..3866065 1 NC_009525.1 transmembrane protein 3866065 5215360 MRA_3478 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284825.1 3865589 D 419947 CDS YP_001284826.1 148663303 5215361 3866075..3866917 1 NC_009525.1 hypothetical protein 3866917 5215361 MRA_3479 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284826.1 3866075 D 419947 CDS YP_001284827.1 148663304 5215362 complement(3866937..3868340) 1 NC_009525.1 hypothetical protein 3868340 5215362 MRA_3480 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284827.1 3866937 R 419947 CDS YP_001284828.1 148663305 5215363 complement(3868343..3868654) 1 NC_009525.1 hypothetical protein 3868654 5215363 MRA_3481 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284828.1 3868343 R 419947 CDS YP_001284829.1 148663306 5215364 complement(3868702..3870048) 1 NC_009525.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3870048 glmM 5215364 glmM Mycobacterium tuberculosis H37Ra phosphoglucosamine mutase YP_001284829.1 3868702 R 419947 CDS YP_001284830.1 148663307 5215365 complement(3870173..3870628) 1 NC_009525.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3870628 rpsI 5215365 rpsI Mycobacterium tuberculosis H37Ra 30S ribosomal protein S9 YP_001284830.1 3870173 R 419947 CDS YP_001284831.1 148663308 5215366 complement(3870625..3871068) 1 NC_009525.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3871068 rplM 5215366 rplM Mycobacterium tuberculosis H37Ra 50S ribosomal protein L13 YP_001284831.1 3870625 R 419947 CDS YP_001284832.1 148663309 5215367 complement(3871301..3871603) 1 NC_009525.1 esat-6 like protein EsxT 3871603 esxT 5215367 esxT Mycobacterium tuberculosis H37Ra esat-6 like protein EsxT YP_001284832.1 3871301 R 419947 CDS YP_001284833.1 148663310 5215368 complement(3871624..3872001) 1 NC_009525.1 esat-6 like protein EsxU 3872001 esxU 5215368 esxU Mycobacterium tuberculosis H37Ra esat-6 like protein EsxU YP_001284833.1 3871624 R 419947 CDS YP_001284834.1 148663311 5211782 complement(3871994..3873208) 1 NC_009525.1 hypothetical protein 3873208 5211782 MRA_3487 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284834.1 3871994 R 419947 CDS YP_001284835.1 148663312 5211783 complement(3873205..3876915) 1 NC_009525.1 hypothetical protein 3876915 5211783 MRA_3488 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284835.1 3873205 R 419947 CDS YP_001284836.1 148663313 5211784 3877029..3878432 1 NC_009525.1 integral membrane protein 3878432 5211784 MRA_3489 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001284836.1 3877029 D 419947 CDS YP_001284837.1 148663314 5211785 3878429..3879796 1 NC_009525.1 membrane-anchored mycosin MycP4 3879796 mycP4 5211785 mycP4 Mycobacterium tuberculosis H37Ra membrane-anchored mycosin MycP4 YP_001284837.1 3878429 D 419947 CDS YP_001284838.1 148663315 5211786 complement(3879761..3881173) 1 NC_009525.1 hypothetical protein 3881173 5211786 MRA_3491 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284838.1 3879761 R 419947 CDS YP_001284839.1 148663316 5211787 3881294..3882082 1 NC_009525.1 cutinase precursor Cut3 3882082 cut3 5211787 cut3 Mycobacterium tuberculosis H37Ra cutinase precursor Cut3 YP_001284839.1 3881294 D 419947 CDS YP_001284840.1 148663317 5211788 3882129..3882809 1 NC_009525.1 cutinase precursor Cut4 3882809 cut4 5211788 cut4 Mycobacterium tuberculosis H37Ra cutinase precursor Cut4 YP_001284840.1 3882129 D 419947 CDS YP_001284841.1 148663318 5211789 3883081..3883413 1 NC_009525.1 transmembrane protein 3883413 5211789 MRA_3494 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001284841.1 3883081 D 419947 CDS YP_001284842.1 148663319 5211790 3883436..3884767 1 NC_009525.1 hypothetical protein 3884767 5211790 MRA_3495 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284842.1 3883436 D 419947 CDS YP_001284843.1 148663320 5214325 complement(3884729..3885499) 1 NC_009525.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 3885499 truA 5214325 truA Mycobacterium tuberculosis H37Ra tRNA pseudouridine synthase A YP_001284843.1 3884729 R 419947 CDS YP_001284844.1 148663321 5214326 complement(3885567..3886109) 1 NC_009525.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3886109 rplQ 5214326 rplQ Mycobacterium tuberculosis H37Ra 50S ribosomal protein L17 YP_001284844.1 3885567 R 419947 CDS YP_001284845.1 148663322 5214327 complement(3886141..3887184) 1 NC_009525.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3887184 rpoA 5214327 rpoA Mycobacterium tuberculosis H37Ra DNA-directed RNA polymerase subunit alpha YP_001284845.1 3886141 R 419947 CDS YP_001284846.1 148663323 5214328 complement(3887336..3887941) 1 NC_009525.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3887941 rpsD 5214328 rpsD Mycobacterium tuberculosis H37Ra 30S ribosomal protein S4 YP_001284846.1 3887336 R 419947 CDS YP_001284847.1 148663324 5214329 complement(3887950..3888369) 1 NC_009525.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3888369 rpsK 5214329 rpsK Mycobacterium tuberculosis H37Ra 30S ribosomal protein S11 YP_001284847.1 3887950 R 419947 CDS YP_001284848.1 148663325 5214330 complement(3888373..3888747) 1 NC_009525.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3888747 rpsM 5214330 rpsM Mycobacterium tuberculosis H37Ra 30S ribosomal protein S13 YP_001284848.1 3888373 R 419947 CDS YP_001284849.1 148663326 5214331 complement(3888963..3889076) 1 NC_009525.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3889076 rpmJ 5214331 rpmJ Mycobacterium tuberculosis H37Ra 50S ribosomal protein L36 YP_001284849.1 3888963 R 419947 CDS YP_001284850.1 148663327 5214332 complement(3889109..3889330) 1 NC_009525.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 3889330 infA 5214332 infA Mycobacterium tuberculosis H37Ra translation initiation factor IF-1 YP_001284850.1 3889109 R 419947 CDS YP_001284851.1 148663328 5214333 3889584..3890441 1 NC_009525.1 hypothetical protein 3890441 5214333 MRA_3504 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284851.1 3889584 D 419947 CDS YP_001284852.1 148663329 5212482 3890514..3891509 1 NC_009525.1 dTDP-glucose-4,6-dehydratase 3891509 rmlB 5212482 rmlB Mycobacterium tuberculosis H37Ra dTDP-glucose-4,6-dehydratase YP_001284852.1 3890514 D 419947 CDS YP_001284853.1 148663330 5212483 3891511..3892119 1 NC_009525.1 dTDP-4-dehydrorhamnose 3,5-epimerase 3892119 rmlC 5212483 rmlC Mycobacterium tuberculosis H37Ra dTDP-4-dehydrorhamnose 3,5-epimerase YP_001284853.1 3891511 D 419947 CDS YP_001284854.1 148663331 5212484 3892641..3893594 1 NC_009525.1 hypothetical protein 3893594 5212484 MRA_3507 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284854.1 3892641 D 419947 CDS YP_001284855.1 148663332 5212485 complement(3893652..3894746) 1 NC_009525.1 dTDP-glucose-4,6-dehydratase-related protein 3894746 5212485 MRA_3508 Mycobacterium tuberculosis H37Ra dTDP-glucose-4,6-dehydratase-related protein YP_001284855.1 3893652 R 419947 CDS YP_001284856.1 148663333 5212486 complement(3894750..3895760) 1 NC_009525.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 3895760 mhpE 5212486 mhpE Mycobacterium tuberculosis H37Ra 4-hydroxy-2-ketovalerate aldolase YP_001284856.1 3894750 R 419947 CDS YP_001284857.1 148663334 5212487 complement(3895821..3897479) 1 NC_009525.1 acetolactate synthase large subunit 3897479 ilvB2 5212487 ilvB2 Mycobacterium tuberculosis H37Ra acetolactate synthase large subunit YP_001284857.1 3895821 R 419947 CDS YP_001284858.1 148663335 5212488 complement(3897485..3898018) 1 NC_009525.1 hypothetical protein 3898018 5212488 MRA_3511 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284858.1 3897485 R 419947 CDS YP_001284859.1 148663336 5212489 3898039..3898545 1 NC_009525.1 hypothetical protein 3898545 5212489 MRA_3512 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284859.1 3898039 D 419947 CDS YP_001284860.1 148663337 5212490 complement(3898625..3899410) 1 NC_009525.1 non-haem peroxidase; peroxidase BpoA 3899410 bpoA 5212490 bpoA Mycobacterium tuberculosis H37Ra peroxidase BpoA YP_001284860.1 3898625 R 419947 CDS YP_001284861.1 148663338 5211658 3899507..3899833 1 NC_009525.1 IS6110 hypothetical protein 3899833 5211658 MRA_3514 Mycobacterium tuberculosis H37Ra IS6110 hypothetical protein YP_001284861.1 3899507 D 419947 CDS YP_001284862.1 148663339 5211659 3899884..3900768 1 NC_009525.1 IS6110 transposase 3900768 5211659 MRA_3515 Mycobacterium tuberculosis H37Ra IS6110 transposase YP_001284862.1 3899884 D 419947 CDS YP_001284863.1 148663340 5211660 complement(3901048..3902397) 1 NC_009525.1 dicarboxylic acid transport integral membrane protein KgtP 3902397 kgtP 5211660 kgtP Mycobacterium tuberculosis H37Ra dicarboxylic acid transport integral membrane protein KgtP YP_001284863.1 3901048 R 419947 CDS YP_001284864.1 148663341 5211661 3902770..3903066 1 NC_009525.1 PE family protein 3903066 5211661 MRA_3517 Mycobacterium tuberculosis H37Ra PE family protein YP_001284864.1 3902770 D 419947 CDS YP_001284865.1 148663342 5211662 3903103..3904284 1 NC_009525.1 PPE family protein 3904284 5211662 MRA_3518 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284865.1 3903103 D 419947 CDS YP_001284866.1 148663343 5211663 3904497..3907562 1 NC_009525.1 hypothetical protein 3907562 5211663 MRA_3519 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284866.1 3904497 D 419947 CDS YP_001284867.1 148663344 5211664 complement(3907586..3909079) 1 NC_009525.1 hypothetical protein 3909079 5211664 MRA_3520 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284867.1 3907586 R 419947 CDS YP_001284868.1 148663345 5211665 complement(3909170..3909859) 1 NC_009525.1 hypothetical protein 3909859 5211665 MRA_3521 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284868.1 3909170 R 419947 CDS YP_001284869.1 148663346 5211666 complement(3910001..3910783) 1 NC_009525.1 hypothetical protein 3910783 5211666 MRA_3522 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284869.1 3910001 R 419947 CDS YP_001284870.1 148663347 5212736 complement(3910827..3911489) 1 NC_009525.1 hypothetical protein 3911489 5212736 MRA_3523 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284870.1 3910827 R 419947 CDS YP_001284871.1 148663348 5212737 3911755..3913293 1 NC_009525.1 hypothetical protein 3913293 cpsA 5212737 cpsA Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284871.1 3911755 D 419947 CDS YP_001284872.1 148663349 5212738 complement(3913299..3914243) 1 NC_009525.1 short chain dehydrogenase 3914243 5212738 MRA_3525 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284872.1 3913299 R 419947 CDS YP_001284873.1 148663350 5212739 3914449..3914898 1 NC_009525.1 hypothetical protein 3914898 5212739 MRA_3526 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284873.1 3914449 D 419947 CDS YP_001284874.1 148663351 5212740 complement(3914851..3915684) 1 NC_009525.1 esterase 3915684 lipF 5212740 lipF Mycobacterium tuberculosis H37Ra esterase YP_001284874.1 3914851 R 419947 CDS YP_001284875.1 148663352 5212741 3916344..3916667 1 NC_009525.1 hypothetical protein 3916667 5212741 MRA_3528 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284875.1 3916344 D 419947 CDS YP_001284876.1 148663353 5212742 3916749..3916913 1 NC_009525.1 hypothetical protein 3916913 5212742 MRA_3529 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284876.1 3916749 D 419947 CDS YP_001284877.1 148663354 5212743 3916913..3918415 1 NC_009525.1 alpha, alpha-trehalose-phosphate synthase 3918415 otsA 5212743 otsA Mycobacterium tuberculosis H37Ra alpha, alpha-trehalose-phosphate synthase YP_001284877.1 3916913 D 419947 CDS YP_001284878.1 148663355 5212744 3918567..3919145 1 NC_009525.1 hypothetical protein 3919145 5212744 MRA_3531 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284878.1 3918567 D 419947 CDS YP_001284879.1 148663356 5214694 complement(3919142..3919624) 1 NC_009525.1 Mce associated protein 3919624 5214694 MRA_3532 Mycobacterium tuberculosis H37Ra Mce associated protein YP_001284879.1 3919142 R 419947 CDS YP_001284880.1 148663357 5214695 complement(3919624..3920352) 1 NC_009525.1 Mce associated alanine and valine rich protein 3920352 5214695 MRA_3533 Mycobacterium tuberculosis H37Ra Mce associated alanine and valine rich protein YP_001284880.1 3919624 R 419947 CDS YP_001284881.1 148663358 5214696 complement(3920352..3922046) 1 NC_009525.1 MCE-family protein Mce4F 3922046 mce4F 5214696 mce4F Mycobacterium tuberculosis H37Ra MCE-family protein Mce4F YP_001284881.1 3920352 R 419947 CDS YP_001284882.1 148663359 5214697 complement(3922057..3923211) 1 NC_009525.1 MCE family lipoprotein LprN 3923211 lprN 5214697 lprN Mycobacterium tuberculosis H37Ra MCE family lipoprotein LprN YP_001284882.1 3922057 R 419947 CDS YP_001284883.1 148663360 5214698 complement(3923208..3924563) 1 NC_009525.1 MCE-family protein Mce4D 3924563 mce4D 5214698 mce4D Mycobacterium tuberculosis H37Ra MCE-family protein Mce4D YP_001284883.1 3923208 R 419947 CDS YP_001284884.1 148663361 5214699 complement(3924560..3925633) 1 NC_009525.1 MCE-family protein Mce4C 3925633 mce4C 5214699 mce4C Mycobacterium tuberculosis H37Ra MCE-family protein Mce4C YP_001284884.1 3924560 R 419947 CDS YP_001284885.1 148663362 5214700 complement(3925623..3926675) 1 NC_009525.1 MCE-family protein Mce4B 3926675 mce4B 5214700 mce4B Mycobacterium tuberculosis H37Ra MCE-family protein Mce4B YP_001284885.1 3925623 R 419947 CDS YP_001284886.1 148663363 5214701 complement(3926675..3927877) 1 NC_009525.1 MCE-family protein Mce4A 3927877 mce4A 5214701 mce4A Mycobacterium tuberculosis H37Ra MCE-family protein Mce4A YP_001284886.1 3926675 R 419947 CDS YP_001284887.1 148663364 5214702 complement(3927897..3928739) 1 NC_009525.1 hypothetical protein 3928739 yrbE4B 5214702 yrbE4B Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284887.1 3927897 R 419947 CDS YP_001284888.1 148663365 5212899 complement(3928774..3929538) 1 NC_009525.1 hypothetical protein 3929538 yrbE4A 5212899 yrbE4A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284888.1 3928774 R 419947 CDS YP_001284889.1 148663366 5212900 complement(3929764..3930717) 1 NC_009525.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 3930717 fabG 5212900 fabG Mycobacterium tuberculosis H37Ra 3-ketoacyl-ACP reductase YP_001284889.1 3929764 R 419947 CDS YP_001284890.1 148663367 5212901 complement(3930742..3930933) 1 NC_009525.1 ferredoxin FdxD 3930933 fdxD 5212901 fdxD Mycobacterium tuberculosis H37Ra ferredoxin FdxD YP_001284890.1 3930742 R 419947 CDS YP_001284891.1 148663368 5212902 3931148..3932350 1 NC_009525.1 acyl-CoA dehydrogenase 3932350 fadE26 5212902 fadE26 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284891.1 3931148 D 419947 CDS YP_001284892.1 148663369 5212903 3932375..3933496 1 NC_009525.1 acyl-CoA dehydrogenase 3933496 fadE27 5212903 fadE27 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284892.1 3932375 D 419947 CDS YP_001284893.1 148663370 5212904 3933567..3935075 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3935075 fadD17 5212904 fadD17 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001284893.1 3933567 D 419947 CDS YP_001284894.1 148663371 5212905 3935246..3939391 1 NC_009525.1 PE-PGRS family protein 3939391 5212905 MRA_3547 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284894.1 3935246 D 419947 CDS YP_001284895.1 148663372 5212906 3939682..3944319 1 NC_009525.1 PE-PGRS family protein 3944319 5212906 MRA_3548 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284895.1 3939682 D 419947 CDS YP_001284896.1 148663373 5212907 complement(3946368..3947915) 1 NC_009525.1 thiamine-pyrophosphate requiring enzyme; hypothetical protein 3947915 ilvX 5212907 ilvX Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284896.1 3946368 R 419947 CDS YP_001284897.1 148663374 5212383 complement(3947912..3948748) 1 NC_009525.1 hypothetical protein 3948748 5212383 MRA_3550 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284897.1 3947912 R 419947 CDS YP_001284898.1 148663375 5212384 3949108..3951261 1 NC_009525.1 PE-PGRS family protein 3951261 5212384 MRA_3551 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284898.1 3949108 D 419947 CDS YP_001284899.1 148663376 5212385 complement(3954592..3955248) 1 NC_009525.1 fatty-acid--CoA ligase 3955248 fadD18 5212385 fadD18 Mycobacterium tuberculosis H37Ra fatty-acid--CoA ligase YP_001284899.1 3954592 R 419947 CDS YP_001284900.1 148663377 5212386 3955294..3958929 1 NC_009525.1 PE-PGRS family protein 3958929 5212386 MRA_3553 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284900.1 3955294 D 419947 CDS YP_001284901.1 148663378 5212387 complement(3959490..3961136) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; acyl-CoA synthetase 3961136 fadD19 5212387 fadD19 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001284901.1 3959490 R 419947 CDS YP_001284902.1 148663379 5212388 3961210..3962001 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3962001 echA19 5212388 echA19 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001284902.1 3961210 D 419947 CDS YP_001284903.1 148663380 5212389 3962097..3962936 1 NC_009525.1 hypothetical protein 3962936 5212389 MRA_3556 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284903.1 3962097 D 419947 CDS YP_001284904.1 148663381 5212390 complement(3962991..3964187) 1 NC_009525.1 cytochrome p450 monooxygenase 142 CYP142 3964187 cyp142 5212390 cyp142 Mycobacterium tuberculosis H37Ra cytochrome p450 monooxygenase 142 CYP142 YP_001284904.1 3962991 R 419947 CDS YP_001284905.1 148663382 5212391 3964216..3964926 1 NC_009525.1 hypothetical protein 3964926 5212391 MRA_3558 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284905.1 3964216 D 419947 CDS YP_001284906.1 148663383 5212616 complement(3964991..3966034) 1 NC_009525.1 N5,N10-methylenetetrahydromethanopterin reductase-related protein 3966034 5212616 MRA_3559 Mycobacterium tuberculosis H37Ra N5,N10-methylenetetrahydromethanopterin reductase-related protein YP_001284906.1 3964991 R 419947 CDS YP_001284907.1 148663384 5212617 3966187..3967098 1 NC_009525.1 hypothetical protein 3967098 5212617 MRA_3560 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284907.1 3966187 D 419947 CDS YP_001284908.1 148663385 5212618 3967114..3968178 1 NC_009525.1 lipid-transfer protein 3968178 ltp4 5212618 ltp4 Mycobacterium tuberculosis H37Ra lipid-transfer protein YP_001284908.1 3967114 D 419947 CDS YP_001284909.1 148663386 5212619 3968195..3969379 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3969379 ltp3 5212619 ltp3 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001284909.1 3968195 D 419947 CDS YP_001284910.1 148663387 5212620 3969421..3970452 1 NC_009525.1 hypothetical protein 3970452 5212620 MRA_3563 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284910.1 3969421 D 419947 CDS YP_001284911.1 148663388 5212621 complement(3970466..3970990) 1 NC_009525.1 siderophore binding protein 3970990 5212621 MRA_3564 Mycobacterium tuberculosis H37Ra siderophore binding protein YP_001284911.1 3970466 R 419947 CDS YP_001284912.1 148663389 5212622 3971105..3972265 1 NC_009525.1 oxidoreductase 3972265 5212622 MRA_3565 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284912.1 3971105 D 419947 CDS YP_001284913.1 148663390 5212623 3972271..3972720 1 NC_009525.1 hypothetical protein 3972720 5212623 MRA_3566 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284913.1 3972271 D 419947 CDS YP_001284914.1 148663391 5212624 complement(3973145..3973858) 1 NC_009525.1 hypothetical protein 3973858 5212624 MRA_3567 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284914.1 3973145 R 419947 CDS YP_001284915.1 148663392 5213465 complement(3974550..3975704) 1 NC_009525.1 hypothetical protein 3975704 5213465 MRA_3568 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284915.1 3974550 R 419947 CDS YP_001284916.1 148663393 5213466 complement(3975704..3976486) 1 NC_009525.1 short chain dehydrogenase 3976486 5213466 MRA_3569 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284916.1 3975704 R 419947 CDS YP_001284917.1 148663394 5213467 complement(3976483..3977610) 1 NC_009525.1 hypothetical protein 3977610 5213467 MRA_3570 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284917.1 3976483 R 419947 CDS YP_001284918.1 148663395 5213468 3978009..3979229 1 NC_009525.1 PPE family protein 3979229 5213468 MRA_3571 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284918.1 3978009 D 419947 CDS YP_001284919.1 148663396 5213469 complement(3979371..3981119) 1 NC_009525.1 PPE family protein 3981119 5213469 MRA_3572 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284919.1 3979371 R 419947 CDS YP_001284920.1 148663397 5213470 complement(3981218..3982258) 1 NC_009525.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 3982258 bphI 5213470 bphI Mycobacterium tuberculosis H37Ra 4-hydroxy-2-ketovalerate aldolase YP_001284920.1 3981218 R 419947 CDS YP_001284921.1 148663398 5213471 complement(3982255..3983166) 1 NC_009525.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 3983166 mhpF 5213471 mhpF Mycobacterium tuberculosis H37Ra acetaldehyde dehydrogenase YP_001284921.1 3982255 R 419947 CDS YP_001284922.1 148663399 5213472 complement(3983177..3983962) 1 NC_009525.1 2-keto-4-pentenoate hydratase 3983962 mhpD 5213472 mhpD Mycobacterium tuberculosis H37Ra 2-keto-4-pentenoate hydratase YP_001284922.1 3983177 R 419947 CDS YP_001284923.1 148663400 5213473 3984035..3985726 1 NC_009525.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 3985726 5213473 MRA_3576 Mycobacterium tuberculosis H37Ra 3-ketosteroid-delta-1-dehydrogenase YP_001284923.1 3984035 D 419947 CDS YP_001284924.1 148663401 5213515 3985728..3986588 1 NC_009525.1 MaoC-like dehydratase 3986588 5213515 MRA_3577 Mycobacterium tuberculosis H37Ra MaoC-like dehydratase YP_001284924.1 3985728 D 419947 CDS YP_001284925.1 148663402 5213516 3986725..3988164 1 NC_009525.1 PPE family protein 3988164 5213516 MRA_3578 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284925.1 3986725 D 419947 CDS YP_001284926.1 148663403 5213517 complement(3988165..3989325) 1 NC_009525.1 lipid-transfer protein 3989325 ltp2 5213517 ltp2 Mycobacterium tuberculosis H37Ra lipid-transfer protein YP_001284926.1 3988165 R 419947 CDS YP_001284927.1 148663404 5213518 complement(3989325..3989714) 1 NC_009525.1 hypothetical protein 3989714 5213518 MRA_3580 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284927.1 3989325 R 419947 CDS YP_001284928.1 148663405 5213519 complement(3989711..3990646) 1 NC_009525.1 hypothetical protein 3990646 5213519 MRA_3581 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284928.1 3989711 R 419947 CDS YP_001284929.1 148663406 5213520 complement(3990643..3991806) 1 NC_009525.1 acyl-CoA dehydrogenase 3991806 fadE29 5213520 fadE29 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284929.1 3990643 R 419947 CDS YP_001284930.1 148663407 5213521 complement(3991791..3992810) 1 NC_009525.1 acyl-CoA dehydrogenase 3992810 fadE28 5213521 fadE28 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284930.1 3991791 R 419947 CDS YP_001284931.1 148663408 5213522 complement(3992810..3994111) 1 NC_009525.1 cytochrome p450 125 CYP125 3994111 cyp125 5213522 cyp125 Mycobacterium tuberculosis H37Ra cytochrome p450 125 CYP125 YP_001284931.1 3992810 R 419947 CDS YP_001284932.1 148663409 5213523 3994223..3995398 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3995398 fadA5 5213523 fadA5 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001284932.1 3994223 D 419947 CDS YP_001284933.1 148663410 5213946 3995510..3995965 1 NC_009525.1 hypothetical protein 3995965 5213946 MRA_3586 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284933.1 3995510 D 419947 CDS YP_001284934.1 148663411 5213947 complement(3996048..3996962) 1 NC_009525.1 short chain dehydrogenase 3996962 5213947 MRA_3587 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284934.1 3996048 R 419947 CDS YP_001284935.1 148663412 5213948 complement(3996985..3997764) 1 NC_009525.1 short chain dehydrogenase 3997764 5213948 MRA_3588 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284935.1 3996985 R 419947 CDS YP_001284936.1 148663413 5213949 3997819..3998562 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3998562 echA20 5213949 echA20 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001284936.1 3997819 D 419947 CDS YP_001284937.1 148663414 5213950 3998562..3999440 1 NC_009525.1 CoA-transferase subunit alpha 3999440 5213950 MRA_3590 Mycobacterium tuberculosis H37Ra CoA-transferase subunit alpha YP_001284937.1 3998562 D 419947 CDS YP_001284938.1 148663415 5213951 3999437..4000189 1 NC_009525.1 CoA-transferase subunit beta 4000189 5213951 MRA_3591 Mycobacterium tuberculosis H37Ra CoA-transferase subunit beta YP_001284938.1 3999437 D 419947 CDS YP_001284939.1 148663416 5213952 4000287..4001354 1 NC_009525.1 oxidoreductase 4001354 5213952 MRA_3592 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284939.1 4000287 D 419947 CDS YP_001284940.1 148663417 5213953 4001351..4003408 1 NC_009525.1 electron transfer protein FdxB 4003408 fdxB 5213953 fdxB Mycobacterium tuberculosis H37Ra electron transfer protein FdxB YP_001284940.1 4001351 D 419947 CDS YP_001284941.1 148663418 5213954 complement(4003496..4004365) 1 NC_009525.1 hypothetical protein 4004365 5213954 MRA_3594 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284941.1 4003496 R 419947 CDS YP_001284942.1 148663419 5214008 complement(4004470..4005630) 1 NC_009525.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 4005630 fadA6 5214008 fadA6 Mycobacterium tuberculosis H37Ra acetyl-CoA acetyltransferase YP_001284942.1 4004470 R 419947 CDS YP_001284943.1 148663420 5214009 complement(4005695..4006297) 1 NC_009525.1 TetR family transcriptional regulator 4006297 5214009 MRA_3596 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284943.1 4005695 R 419947 CDS YP_001284944.1 148663421 5214010 4006646..4008304 1 NC_009525.1 PPE family protein 4008304 5214010 MRA_3597 Mycobacterium tuberculosis H37Ra PPE family protein YP_001284944.1 4006646 D 419947 CDS YP_001284945.1 148663422 5214011 complement(4008313..4009101) 1 NC_009525.1 short chain dehydrogenase 4009101 5214011 MRA_3598 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001284945.1 4008313 R 419947 CDS YP_001284946.1 148663423 5214012 complement(4009098..4010255) 1 NC_009525.1 acyl-CoA dehydrogenase 4010255 fadE30 5214012 fadE30 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284946.1 4009098 R 419947 CDS YP_001284947.1 148663424 5214013 4010303..4011826 1 NC_009525.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 4011826 fadD3 5214013 fadD3 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--CoA ligase YP_001284947.1 4010303 D 419947 CDS YP_001284948.1 148663425 5214014 4011827..4012960 1 NC_009525.1 acyl-CoA dehydrogenase 4012960 fadE31 5214014 fadE31 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284948.1 4011827 D 419947 CDS YP_001284949.1 148663426 5214015 4012957..4013916 1 NC_009525.1 acyl-CoA dehydrogenase 4013916 fadE32 5214015 fadE32 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284949.1 4012957 D 419947 CDS YP_001284950.1 148663427 5214016 4013913..4014869 1 NC_009525.1 acyl-CoA dehydrogenase 4014869 fadE33 5214016 fadE33 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284950.1 4013913 D 419947 CDS YP_001284951.1 148663428 5214050 4014866..4016032 1 NC_009525.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 4016032 aspB 5214050 aspB Mycobacterium tuberculosis H37Ra aspartate aminotransferase YP_001284951.1 4014866 D 419947 CDS YP_001284952.1 148663429 5214051 complement(4015997..4016848) 1 NC_009525.1 arylamine N-acetyltransferase 4016848 nat 5214051 nat Mycobacterium tuberculosis H37Ra arylamine N-acetyltransferase YP_001284952.1 4015997 R 419947 CDS YP_001284953.1 148663430 5214052 complement(4016833..4017099) 1 NC_009525.1 hypothetical protein 4017099 5214052 MRA_3605A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284953.1 4016833 R 419947 CDS YP_001284954.1 148663431 5214053 complement(4017385..4017948) 1 NC_009525.1 oxidoreductase 4017948 5214053 MRA_3606 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001284954.1 4017385 R 419947 CDS YP_001284955.1 148663432 5214054 complement(4017963..4018865) 1 NC_009525.1 extradiol ring-cleavage dioxygenase 4018865 bphC 5214054 bphC Mycobacterium tuberculosis H37Ra extradiol ring-cleavage dioxygenase YP_001284955.1 4017963 R 419947 CDS YP_001284956.1 148663433 5214055 complement(4018862..4019737) 1 NC_009525.1 2-hydroxy-6-phenylhexa-2,4-dienoic acid hydrolase 4019737 bphD 5214055 bphD Mycobacterium tuberculosis H37Ra 2-hydroxy-6-phenylhexa-2,4-dienoic acid hydrolase YP_001284956.1 4018862 R 419947 CDS YP_001284957.1 148663434 5214056 complement(4019752..4020936) 1 NC_009525.1 hydroxylase 4020936 5214056 MRA_3609 Mycobacterium tuberculosis H37Ra hydroxylase YP_001284957.1 4019752 R 419947 CDS YP_001284958.1 148663435 5214057 4021083..4022159 1 NC_009525.1 hemoglobine-related protein Hmp 4022159 hmp 5214057 hmp Mycobacterium tuberculosis H37Ra hemoglobine-related protein Hmp YP_001284958.1 4021083 D 419947 CDS YP_001284959.1 148663436 5214058 4022177..4022707 1 NC_009525.1 hypothetical protein 4022707 5214058 MRA_3611 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284959.1 4022177 D 419947 CDS YP_001284960.1 148663437 5214103 complement(4022743..4024878) 1 NC_009525.1 acyl-CoA dehydrogenase 4024878 fadE34 5214103 fadE34 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001284960.1 4022743 R 419947 CDS YP_001284961.1 148663438 5214104 4025150..4025749 1 NC_009525.1 TetR family transcriptional regulator 4025749 5214104 MRA_3613 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001284961.1 4025150 D 419947 CDS YP_001284962.1 148663439 5214105 complement(4025755..4026834) 1 NC_009525.1 LacI family transcriptional regulator 4026834 5214105 MRA_3614 Mycobacterium tuberculosis H37Ra LacI family transcriptional regulator YP_001284962.1 4025755 R 419947 CDS YP_001284963.1 148663440 5214106 4027024..4027737 1 NC_009525.1 lipoprotein LppH 4027737 lppH 5214106 lppH Mycobacterium tuberculosis H37Ra lipoprotein LppH YP_001284963.1 4027024 D 419947 CDS YP_001284964.1 148663441 5214107 4027928..4028794 1 NC_009525.1 hypothetical protein 4028794 5214107 MRA_3616 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284964.1 4027928 D 419947 CDS YP_001284965.1 148663442 5214108 4028808..4030049 1 NC_009525.1 arsenical pump integral membrane protein ArsB2 4030049 arsB2 5214108 arsB2 Mycobacterium tuberculosis H37Ra arsenical pump integral membrane protein ArsB2 YP_001284965.1 4028808 D 419947 CDS YP_001284966.1 148663443 5214109 complement(4030091..4031059) 1 NC_009525.1 tRNA/rRNA methyltransferase 4031059 5214109 MRA_3618 Mycobacterium tuberculosis H37Ra tRNA/rRNA methyltransferase YP_001284966.1 4030091 R 419947 CDS YP_001284967.1 148663444 5214110 complement(4031060..4032469) 1 NC_009525.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 4032469 cysS 5214110 cysS Mycobacterium tuberculosis H37Ra cysteinyl-tRNA synthetase YP_001284967.1 4031060 R 419947 CDS YP_001284968.1 148663445 5214111 complement(4032534..4033013) 1 NC_009525.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4033013 ispF 5214111 ispF Mycobacterium tuberculosis H37Ra 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001284968.1 4032534 R 419947 CDS YP_001284969.1 148663446 5214922 complement(4033010..4033705) 1 NC_009525.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4033705 ispD 5214922 ispD Mycobacterium tuberculosis H37Ra 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001284969.1 4033010 R 419947 CDS YP_001284970.1 148663447 5214923 complement(4033722..4034210) 1 NC_009525.1 transcription factor 4034210 5214923 MRA_3622 Mycobacterium tuberculosis H37Ra transcription factor YP_001284970.1 4033722 R 419947 CDS YP_001284971.1 148663448 5214924 4034496..4035044 1 NC_009525.1 lipoprotein LpqE 4035044 lpqE 5214924 lpqE Mycobacterium tuberculosis H37Ra lipoprotein LpqE YP_001284971.1 4034496 D 419947 CDS YP_001284972.1 148663449 5214925 4035110..4036552 1 NC_009525.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4036552 radA 5214925 radA Mycobacterium tuberculosis H37Ra DNA repair protein RadA YP_001284972.1 4035110 D 419947 CDS YP_001284973.1 148663450 5214926 4036557..4037633 1 NC_009525.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 4037633 5214926 MRA_3625 Mycobacterium tuberculosis H37Ra DNA integrity scanning protein DisA YP_001284973.1 4036557 D 419947 CDS YP_001284974.1 148663451 5214927 complement(4037634..4038428) 1 NC_009525.1 hypothetical protein 4038428 5214927 MRA_3626 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284974.1 4037634 R 419947 CDS YP_001284975.1 148663452 5214928 complement(4038537..4039160) 1 NC_009525.1 carbonic anhydrase 4039160 5214928 MRA_3627 Mycobacterium tuberculosis H37Ra carbonic anhydrase YP_001284975.1 4038537 R 419947 CDS YP_001284976.1 148663453 5214929 4039159..4040073 1 NC_009525.1 A/G-specific adenine glycosylase 4040073 mutY 5214929 mutY Mycobacterium tuberculosis H37Ra A/G-specific adenine glycosylase YP_001284976.1 4039159 D 419947 CDS YP_001284977.1 148663454 5214930 complement(4040070..4041824) 1 NC_009525.1 PE-PGRS family protein 4041824 5214930 MRA_3629 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284977.1 4040070 R 419947 CDS YP_001284978.1 148663455 5215147 complement(4041935..4042708) 1 NC_009525.1 alpha/beta hydrolase 4042708 5215147 MRA_3630 Mycobacterium tuberculosis H37Ra alpha/beta hydrolase YP_001284978.1 4041935 R 419947 CDS YP_001284979.1 148663456 5215148 4042723..4043040 1 NC_009525.1 hypothetical protein 4043040 5215148 MRA_3631 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284979.1 4042723 D 419947 CDS YP_001284980.1 148663457 5215149 4043018..4044376 1 NC_009525.1 lipoprotein LpqF 4044376 lpqF 5215149 lpqF Mycobacterium tuberculosis H37Ra lipoprotein LpqF YP_001284980.1 4043018 D 419947 CDS YP_001284981.1 148663458 5215150 4044523..4045350 1 NC_009525.1 hypothetical protein 4045350 5215150 MRA_3633 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284981.1 4044523 D 419947 CDS YP_001284982.1 148663459 5215151 complement(4045264..4045962) 1 NC_009525.1 PE-PGRS family protein 4045962 5215151 MRA_3634 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284982.1 4045264 R 419947 CDS YP_001284983.1 148663460 5215152 complement(4045999..4046715) 1 NC_009525.1 PE-PGRS family protein 4046715 5215152 MRA_3635 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001284983.1 4045999 R 419947 CDS YP_001284984.1 148663461 5215153 complement(4046823..4049369) 1 NC_009525.1 ATP-dependent Clp protease ATP-binding subunit ClpC 4049369 clpC1 5215153 clpC1 Mycobacterium tuberculosis H37Ra ATP-dependent Clp protease ATP-binding subunit ClpC YP_001284984.1 4046823 R 419947 CDS YP_001284985.1 148663462 5215154 complement(4049646..4049984) 1 NC_009525.1 iron-regulated Lsr2 protein precursor 4049984 lsr2 5215154 lsr2 Mycobacterium tuberculosis H37Ra iron-regulated Lsr2 protein precursor YP_001284985.1 4049646 R 419947 CDS YP_001284986.1 148663463 5215155 complement(4050088..4051605) 1 NC_009525.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4051605 lysS 5215155 lysS Mycobacterium tuberculosis H37Ra lysyl-tRNA synthetase YP_001284986.1 4050088 R 419947 CDS YP_001284987.1 148663464 5214615 complement(4051706..4052524) 1 NC_009525.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 4052524 5214615 MRA_3639 Mycobacterium tuberculosis H37Ra pantothenate kinase YP_001284987.1 4051706 R 419947 CDS YP_001284988.1 148663465 5214616 complement(4052527..4052946) 1 NC_009525.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 4052946 panD 5214616 panD Mycobacterium tuberculosis H37Ra aspartate alpha-decarboxylase YP_001284988.1 4052527 R 419947 CDS YP_001284989.1 148663466 5214617 complement(4052946..4053875) 1 NC_009525.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 4053875 panC 5214617 panC Mycobacterium tuberculosis H37Ra pantoate--beta-alanine ligase YP_001284989.1 4052946 R 419947 CDS YP_001284990.1 148663467 5214618 complement(4053872..4054783) 1 NC_009525.1 hypothetical protein 4054783 5214618 MRA_3642 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284990.1 4053872 R 419947 CDS YP_001284991.1 148663468 5214619 complement(4054968..4056161) 1 NC_009525.1 alanine, arginine and proline rich transmembrane protein 4056161 5214619 MRA_3643 Mycobacterium tuberculosis H37Ra alanine, arginine and proline rich transmembrane protein YP_001284991.1 4054968 R 419947 CDS YP_001284992.1 148663469 5214620 complement(4056370..4056846) 1 NC_009525.1 hypothetical protein 4056846 5214620 MRA_3644 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284992.1 4056370 R 419947 CDS YP_001284993.1 148663470 5214621 complement(4056846..4057412) 1 NC_009525.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 4057412 folK 5214621 folK Mycobacterium tuberculosis H37Ra 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001284993.1 4056846 R 419947 CDS YP_001284994.1 148663471 5214622 complement(4057409..4057810) 1 NC_009525.1 dihydroneopterin aldolase 4057810 folB 5214622 folB Mycobacterium tuberculosis H37Ra dihydroneopterin aldolase YP_001284994.1 4057409 R 419947 CDS YP_001284995.1 148663472 5214623 complement(4057803..4058645) 1 NC_009525.1 dihydropteroate synthase 4058645 folP1 5214623 folP1 Mycobacterium tuberculosis H37Ra dihydropteroate synthase YP_001284995.1 4057803 R 419947 CDS YP_001284996.1 148663473 5215428 complement(4058642..4059250) 1 NC_009525.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 4059250 folE 5215428 folE Mycobacterium tuberculosis H37Ra GTP cyclohydrolase I YP_001284996.1 4058642 R 419947 CDS YP_001284997.1 148663474 5215429 complement(4059266..4061548) 1 NC_009525.1 cell division protein FtsH 4061548 ftsH 5215429 ftsH Mycobacterium tuberculosis H37Ra cell division protein FtsH YP_001284997.1 4059266 R 419947 CDS YP_001284998.1 148663475 5215430 complement(4061965..4062294) 1 NC_009525.1 hypothetical protein 4062294 5215430 MRA_3649A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284998.1 4061965 R 419947 CDS YP_001284999.1 148663476 5215431 complement(4062328..4062489) 1 NC_009525.1 hypothetical protein 4062489 5215431 MRA_3649B Mycobacterium tuberculosis H37Ra hypothetical protein YP_001284999.1 4062328 R 419947 CDS YP_001285000.1 148663477 5215432 complement(4062589..4063143) 1 NC_009525.1 hypothetical protein 4063143 5215432 MRA_3650 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285000.1 4062589 R 419947 CDS YP_001285001.1 148663478 5215433 complement(4063259..4063570) 1 NC_009525.1 hypothetical protein 4063570 5215433 MRA_3651 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285001.1 4063259 R 419947 CDS YP_001285002.1 148663479 5215434 complement(4063644..4064822) 1 NC_009525.1 hypothetical protein 4064822 5215434 MRA_3652 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285002.1 4063644 R 419947 CDS YP_001285003.1 148663480 5215435 4066180..4067148 1 NC_009525.1 epoxide hydrolase 4067148 ephA 5215435 ephA Mycobacterium tuberculosis H37Ra epoxide hydrolase YP_001285003.1 4066180 D 419947 CDS YP_001285004.1 148663481 5215436 4067145..4068332 1 NC_009525.1 monooxygenase 4068332 5215436 MRA_3654 Mycobacterium tuberculosis H37Ra monooxygenase YP_001285004.1 4067145 D 419947 CDS YP_001285005.1 148663482 5213209 complement(4068431..4068715) 1 NC_009525.1 esat-6 like protein EsxV 4068715 esxV2 5213209 esxV2 Mycobacterium tuberculosis H37Ra esat-6 like protein EsxV YP_001285005.1 4068431 R 419947 CDS YP_001285006.1 148663483 5213210 complement(4068742..4069038) 1 NC_009525.1 esat-6 like protein EsxW 4069038 esxW 5213210 esxW Mycobacterium tuberculosis H37Ra esat-6 like protein EsxW YP_001285006.1 4068742 R 419947 CDS YP_001285007.1 148663484 5213211 complement(4069095..4070336) 1 NC_009525.1 PPE family protein 4070336 5213211 MRA_3657 Mycobacterium tuberculosis H37Ra PPE family protein YP_001285007.1 4069095 R 419947 CDS YP_001285008.1 148663485 5213212 complement(4070346..4070645) 1 NC_009525.1 PE family protein 4070645 5213212 MRA_3658 Mycobacterium tuberculosis H37Ra PE family protein YP_001285008.1 4070346 R 419947 CDS YP_001285009.1 148663486 5213213 4070974..4071696 1 NC_009525.1 lipoprotein LpqG 4071696 lpqG 5213213 lpqG Mycobacterium tuberculosis H37Ra lipoprotein LpqG YP_001285009.1 4070974 D 419947 CDS YP_001285010.1 148663487 5213214 complement(4071701..4072351) 1 NC_009525.1 hypoxanthine-guanine phosphoribosyltransferase 4072351 hpt 5213214 hpt Mycobacterium tuberculosis H37Ra hypoxanthine-guanine phosphoribosyltransferase YP_001285010.1 4071701 R 419947 CDS YP_001285011.1 148663488 5213215 complement(4072348..4073319) 1 NC_009525.1 cell cycle protein MesJ 4073319 mesJ 5213215 mesJ Mycobacterium tuberculosis H37Ra cell cycle protein MesJ YP_001285011.1 4072348 R 419947 CDS YP_001285012.1 148663489 5213216 complement(4073298..4074350) 1 NC_009525.1 hypothetical protein 4074350 5213216 MRA_3662 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285012.1 4073298 R 419947 CDS YP_001285013.1 148663490 5213217 complement(4074347..4075732) 1 NC_009525.1 D-alanyl-D-alanine carboxypeptidase 4075732 5213217 MRA_3663 Mycobacterium tuberculosis H37Ra D-alanyl-D-alanine carboxypeptidase YP_001285013.1 4074347 R 419947 CDS YP_001285014.1 148663491 5213817 4075870..4076358 1 NC_009525.1 inorganic pyrophosphatase 4076358 ppa 5213817 ppa Mycobacterium tuberculosis H37Ra inorganic pyrophosphatase YP_001285014.1 4075870 D 419947 CDS YP_001285015.1 148663492 5213818 complement(4076404..4077501) 1 NC_009525.1 hypothetical protein 4077501 5213818 MRA_3665 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285015.1 4076404 R 419947 CDS YP_001285016.1 148663493 5213819 4077622..4078917 1 NC_009525.1 integral membrane protein 4078917 5213819 MRA_3666 Mycobacterium tuberculosis H37Ra integral membrane protein YP_001285016.1 4077622 D 419947 CDS YP_001285017.1 148663494 5213820 4078961..4079686 1 NC_009525.1 glycosyl transferase 4079686 5213820 MRA_3667 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001285017.1 4078961 D 419947 CDS YP_001285018.1 148663495 5213821 4079683..4080027 1 NC_009525.1 hypothetical protein 4080027 5213821 MRA_3668 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285018.1 4079683 D 419947 CDS YP_001285019.1 148663496 5213822 4080238..4081113 1 NC_009525.1 hypothetical protein 4081113 5213822 MRA_3669 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285019.1 4080238 D 419947 CDS YP_001285020.1 148663497 5213823 complement(4081114..4082058) 1 NC_009525.1 NAD-dependent epimerase/dehydratase 4082058 galE1 5213823 galE1 Mycobacterium tuberculosis H37Ra NAD-dependent epimerase/dehydratase YP_001285020.1 4081114 R 419947 CDS YP_001285021.1 148663498 5213824 4082081..4083856 1 NC_009525.1 hypothetical protein 4083856 5213824 MRA_3671 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285021.1 4082081 D 419947 CDS YP_001285022.1 148663499 5213825 4084199..4084546 1 NC_009525.1 ISMt3-like transposase A1 4084546 5213825 MRA_3672 Mycobacterium tuberculosis H37Ra ISMt3-like transposase A1 YP_001285022.1 4084199 D 419947 CDS YP_001285023.1 148663500 5212745 4084931..4085431 1 NC_009525.1 ISMt3-like transposase A2 4085431 5212745 MRA_3673 Mycobacterium tuberculosis H37Ra ISMt3-like transposase A2 YP_001285023.1 4084931 D 419947 CDS YP_001285024.1 148663501 5212746 4085431..4086177 1 NC_009525.1 transposase 4086177 5212746 MRA_3674 Mycobacterium tuberculosis H37Ra transposase YP_001285024.1 4085431 D 419947 CDS YP_001285025.1 148663502 5212747 complement(4086331..4086897) 1 NC_009525.1 hypothetical protein 4086897 5212747 MRA_3675 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285025.1 4086331 R 419947 CDS YP_001285026.1 148663503 5212748 complement(4086967..4088196) 1 NC_009525.1 IS1245-like transposase 4088196 5212748 MRA_3676 Mycobacterium tuberculosis H37Ra IS1245-like transposase YP_001285026.1 4086967 R 419947 CDS YP_001285027.1 148663504 5212749 complement(4088372..4089007) 1 NC_009525.1 cell filamentation protein Fic 4089007 fic 5212749 fic Mycobacterium tuberculosis H37Ra cell filamentation protein Fic YP_001285027.1 4088372 R 419947 CDS YP_001285028.1 148663505 5212750 complement(4089018..4089212) 1 NC_009525.1 hypothetical protein 4089212 5212750 MRA_3677A Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285028.1 4089018 R 419947 CDS YP_001285029.1 148663506 5212751 4089607..4089798 1 NC_009525.1 hypothetical protein 4089798 5212751 MRA_3678 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285029.1 4089607 D 419947 CDS YP_001285030.1 148663507 5212753 complement(4089963..4091168) 1 NC_009525.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 4091168 5212753 MRA_3679 Mycobacterium tuberculosis H37Ra DNA polymerase III subunit delta' YP_001285030.1 4089963 R 419947 CDS YP_001285031.1 148663508 5212712 4091254..4092903 1 NC_009525.1 adenylate cyclase 4092903 5212712 MRA_3680 Mycobacterium tuberculosis H37Ra adenylate cyclase YP_001285031.1 4091254 D 419947 CDS YP_001285032.1 148663509 5212713 complement(4092900..4095704) 1 NC_009525.1 omega-protein; catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 4095704 topA 5212713 topA Mycobacterium tuberculosis H37Ra DNA topoisomerase I YP_001285032.1 4092900 R 419947 CDS YP_001285033.1 148663510 5212714 complement(4096057..4096635) 1 NC_009525.1 hypothetical protein 4096635 5212714 MRA_3682 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285033.1 4096057 R 419947 CDS YP_001285034.1 148663511 5212715 complement(4096775..4096978) 1 NC_009525.1 cold shock protein A 4096978 cspA 5212715 cspA Mycobacterium tuberculosis H37Ra cold shock protein A YP_001285034.1 4096775 R 419947 CDS YP_001285035.1 148663512 5212716 4097228..4099543 1 NC_009525.1 DeaD/DeaH box family ATP-dependent RNA helicase 4099543 5212716 MRA_3684 Mycobacterium tuberculosis H37Ra DeaD/DeaH box family ATP-dependent RNA helicase YP_001285035.1 4097228 D 419947 CDS YP_001285036.1 148663513 5212717 4099680..4099964 1 NC_009525.1 PE family protein 4099964 5212717 MRA_3685 Mycobacterium tuberculosis H37Ra PE family protein YP_001285036.1 4099680 D 419947 CDS YP_001285037.1 148663514 5212718 4100288..4101325 1 NC_009525.1 hypothetical protein 4101325 5212718 MRA_3686 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285037.1 4100288 D 419947 CDS YP_001285038.1 148663515 5212719 complement(4101840..4102085) 1 NC_009525.1 hypothetical protein 4102085 5212719 MRA_3687 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285038.1 4101840 R 419947 CDS YP_001285039.1 148663516 5213390 4102246..4102974 1 NC_009525.1 PE-PGRS family protein 4102974 5213390 MRA_3688 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001285039.1 4102246 D 419947 CDS YP_001285040.1 148663517 5213391 complement(4103107..4103430) 1 NC_009525.1 hypothetical protein 4103430 5213391 MRA_3689 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285040.1 4103107 R 419947 CDS YP_001285041.1 148663518 5213392 complement(4103447..4103989) 1 NC_009525.1 hypothetical protein 4103989 5213392 MRA_3690 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285041.1 4103447 R 419947 CDS YP_001285042.1 148663519 5213393 complement(4103986..4104666) 1 NC_009525.1 alanine rich membrane protein 4104666 5213393 MRA_3691 Mycobacterium tuberculosis H37Ra alanine rich membrane protein YP_001285042.1 4103986 R 419947 CDS YP_001285043.1 148663520 5213394 complement(4104585..4105385) 1 NC_009525.1 transmembrane protein 4105385 5213394 MRA_3692 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285043.1 4104585 R 419947 CDS YP_001285044.1 148663521 5213395 complement(4105382..4106440) 1 NC_009525.1 secretory protein 4106440 5213395 MRA_3693 Mycobacterium tuberculosis H37Ra secretory protein YP_001285044.1 4105382 R 419947 CDS YP_001285045.1 148663522 5213396 complement(4106542..4107594) 1 NC_009525.1 hypothetical protein 4107594 5213396 MRA_3694 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285045.1 4106542 R 419947 CDS YP_001285046.1 148663523 5213397 4108093..4108956 1 NC_009525.1 hypothetical protein 4108956 5213397 MRA_3695 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285046.1 4108093 D 419947 CDS YP_001285047.1 148663524 5213398 complement(4109711..4110481) 1 NC_009525.1 hypothetical protein 4110481 5213398 MRA_3696 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285047.1 4109711 R 419947 CDS YP_001285048.1 148663525 5213319 complement(4110478..4112124) 1 NC_009525.1 peptide ABC transporter ATP-binding protein 4112124 dppD 5213319 dppD Mycobacterium tuberculosis H37Ra peptide ABC transporter ATP-binding protein YP_001285048.1 4110478 R 419947 CDS YP_001285049.1 148663526 5213320 complement(4112121..4112921) 1 NC_009525.1 peptide ABC transporter permease 4112921 dppC 5213320 dppC Mycobacterium tuberculosis H37Ra peptide ABC transporter permease YP_001285049.1 4112121 R 419947 CDS YP_001285050.1 148663527 5213321 complement(4112977..4113903) 1 NC_009525.1 peptide ABC transporter permease 4113903 dppB 5213321 dppB Mycobacterium tuberculosis H37Ra peptide ABC transporter permease YP_001285050.1 4112977 R 419947 CDS YP_001285051.1 148663528 5213322 complement(4113905..4115530) 1 NC_009525.1 peptide ABC transporter permease 4115530 dppA 5213322 dppA Mycobacterium tuberculosis H37Ra peptide ABC transporter permease YP_001285051.1 4113905 R 419947 CDS YP_001285052.1 148663529 5213323 4115616..4115972 1 NC_009525.1 peptide ABC transporter substrate-binding protein 4115972 5213323 MRA_3701 Mycobacterium tuberculosis H37Ra peptide ABC transporter substrate-binding protein YP_001285052.1 4115616 D 419947 CDS YP_001285053.1 148663530 5213324 4116238..4118193 1 NC_009525.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4118193 acs 5213324 acs Mycobacterium tuberculosis H37Ra acetyl-CoA synthetase YP_001285053.1 4116238 D 419947 CDS YP_001285054.1 148663531 5213325 complement(4118229..4118927) 1 NC_009525.1 protease 4118927 5213325 MRA_3703 Mycobacterium tuberculosis H37Ra protease YP_001285054.1 4118229 R 419947 CDS YP_001285055.1 148663532 5213326 4119273..4119791 1 NC_009525.1 transmembrane protein 4119791 5213326 MRA_3704 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285055.1 4119273 D 419947 CDS YP_001285056.1 148663533 5213327 4119792..4120775 1 NC_009525.1 epoxide hydrolase EphE 4120775 ephE 5213327 ephE Mycobacterium tuberculosis H37Ra epoxide hydrolase EphE YP_001285056.1 4119792 D 419947 CDS YP_001285057.1 148663534 5213643 complement(4120768..4121961) 1 NC_009525.1 membrane-associated serine protease 4121961 5213643 MRA_3706 Mycobacterium tuberculosis H37Ra membrane-associated serine protease YP_001285057.1 4120768 R 419947 CDS YP_001285058.1 148663535 5213644 complement(4121967..4122788) 1 NC_009525.1 hypothetical protein 4122788 5213644 MRA_3707 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285058.1 4121967 R 419947 CDS YP_001285059.1 148663536 5213645 complement(4122920..4123603) 1 NC_009525.1 thioredoxin-related protein 4123603 5213645 MRA_3708 Mycobacterium tuberculosis H37Ra thioredoxin-related protein YP_001285059.1 4122920 R 419947 CDS YP_001285060.1 148663537 5213646 complement(4123603..4124340) 1 NC_009525.1 ultraviolet N-glycosylase/AP lyase 4124340 nth 5213646 nth Mycobacterium tuberculosis H37Ra ultraviolet N-glycosylase/AP lyase YP_001285060.1 4123603 R 419947 CDS YP_001285061.1 148663538 5213647 4124448..4124825 1 NC_009525.1 hypothetical protein 4124825 5213647 MRA_3710 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285061.1 4124448 D 419947 CDS YP_001285062.1 148663539 5213648 4124924..4125598 1 NC_009525.1 Crp/Fnr family transcriptional regulator 4125598 5213648 MRA_3711 Mycobacterium tuberculosis H37Ra Crp/Fnr family transcriptional regulator YP_001285062.1 4124924 D 419947 CDS YP_001285063.1 148663540 5213649 complement(4125704..4126498) 1 NC_009525.1 hydrolase 4126498 5213649 MRA_3712 Mycobacterium tuberculosis H37Ra hydrolase YP_001285063.1 4125704 R 419947 CDS YP_001285064.1 148663541 5213650 complement(4126505..4126960) 1 NC_009525.1 hypothetical protein 4126960 5213650 MRA_3713 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285064.1 4126505 R 419947 CDS YP_001285065.1 148663542 5213651 4127222..4128244 1 NC_009525.1 anion transporter ATPase 4128244 5213651 MRA_3714 Mycobacterium tuberculosis H37Ra anion transporter ATPase YP_001285065.1 4127222 D 419947 CDS YP_001285066.1 148663543 5214218 4128241..4129401 1 NC_009525.1 anion transporter ATPase 4129401 5214218 MRA_3715 Mycobacterium tuberculosis H37Ra anion transporter ATPase YP_001285066.1 4128241 D 419947 CDS YP_001285067.1 148663544 5214219 complement(4129644..4130000) 1 NC_009525.1 WhiB-related protein 4130000 whiB4 5214219 whiB4 Mycobacterium tuberculosis H37Ra WhiB-related protein YP_001285067.1 4129644 R 419947 CDS YP_001285068.1 148663545 5214220 4130362..4132794 1 NC_009525.1 bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 4132794 ponA2 5214220 ponA2 Mycobacterium tuberculosis H37Ra bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 YP_001285068.1 4130362 D 419947 CDS YP_001285069.1 148663546 5214221 4132863..4133822 1 NC_009525.1 hypothetical protein 4133822 5214221 MRA_3718 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285069.1 4132863 D 419947 CDS YP_001285070.1 148663547 5214222 4133885..4134925 1 NC_009525.1 cysteine synthase/cystathionine beta-synthase 4134925 5214222 MRA_3719 Mycobacterium tuberculosis H37Ra cysteine synthase/cystathionine beta-synthase YP_001285070.1 4133885 D 419947 CDS YP_001285071.1 148663548 5214224 complement(4135741..4137171) 1 NC_009525.1 cytochrome p450 137 CYP137 4137171 cyp137 5214224 cyp137 Mycobacterium tuberculosis H37Ra cytochrome p450 137 CYP137 YP_001285071.1 4135741 R 419947 CDS YP_001285072.1 148663549 5214225 complement(4137197..4137529) 1 NC_009525.1 hypothetical protein 4137529 5214225 MRA_3721 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285072.1 4137197 R 419947 CDS YP_001285073.1 148663550 5214455 complement(4137769..4138137) 1 NC_009525.1 anti-anti-sigma factor RsfB 4138137 rsfB 5214455 rsfB Mycobacterium tuberculosis H37Ra anti-anti-sigma factor RsfB YP_001285073.1 4137769 R 419947 CDS YP_001285074.1 148663551 5214456 complement(4138339..4138803) 1 NC_009525.1 hypothetical protein 4138803 5214456 MRA_3723 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285074.1 4138339 R 419947 CDS YP_001285075.1 148663552 5214457 4138803..4140158 1 NC_009525.1 transmembrane protein 4140158 5214457 MRA_3724 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285075.1 4138803 D 419947 CDS YP_001285076.1 148663553 5214458 4140185..4140838 1 NC_009525.1 hypothetical protein 4140838 5214458 MRA_3725 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285076.1 4140185 D 419947 CDS YP_001285077.1 148663554 5214459 4140964..4141965 1 NC_009525.1 hypothetical protein 4141965 5214459 MRA_3726 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285077.1 4140964 D 419947 CDS YP_001285078.1 148663555 5214460 4141962..4143038 1 NC_009525.1 methanol dehydrogenase transcriptional regulatory protein MoxR2 4143038 moxR2 5214460 moxR2 Mycobacterium tuberculosis H37Ra methanol dehydrogenase transcriptional regulatory protein MoxR2 YP_001285078.1 4141962 D 419947 CDS YP_001285079.1 148663556 5214461 4143172..4144494 1 NC_009525.1 hypothetical protein 4144494 5214461 MRA_3728 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285079.1 4143172 D 419947 CDS YP_001285080.1 148663557 5214462 complement(4144568..4145560) 1 NC_009525.1 hypothetical protein 4145560 5214462 MRA_3729 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285080.1 4144568 R 419947 CDS YP_001285081.1 148663558 5214463 4145652..4146584 1 NC_009525.1 hypothetical protein 4146584 5214463 MRA_3730 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285081.1 4145652 D 419947 CDS YP_001285082.1 148663559 5214476 complement(4146648..4148201) 1 NC_009525.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4148201 glpK 5214476 glpK Mycobacterium tuberculosis H37Ra glycerol kinase YP_001285082.1 4146648 R 419947 CDS YP_001285083.1 148663560 5214477 complement(4148251..4148688) 1 NC_009525.1 hypothetical protein 4148688 5214477 MRA_3732 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285083.1 4148251 R 419947 CDS YP_001285084.1 148663561 5214478 complement(4148685..4148909) 1 NC_009525.1 hypothetical protein 4148909 5214478 MRA_3733 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285084.1 4148685 R 419947 CDS YP_001285085.1 148663562 5214479 4148939..4150468 1 NC_009525.1 hypothetical protein 4150468 5214479 MRA_3734 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285085.1 4148939 D 419947 CDS YP_001285086.1 148663563 5214480 4150490..4151191 1 NC_009525.1 hypothetical protein 4151191 5214480 MRA_3735 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285086.1 4150490 D 419947 CDS YP_001285087.1 148663564 5214481 complement(4151194..4152366) 1 NC_009525.1 pyridoxal-phosphate-dependent transferase 4152366 5214481 MRA_3736 Mycobacterium tuberculosis H37Ra pyridoxal-phosphate-dependent transferase YP_001285087.1 4151194 R 419947 CDS YP_001285088.1 148663565 5214482 complement(4152397..4153362) 1 NC_009525.1 hypothetical protein 4153362 5214482 MRA_3737 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285088.1 4152397 R 419947 CDS YP_001285089.1 148663566 5214483 complement(4153359..4154060) 1 NC_009525.1 hypothetical protein 4154060 5214483 MRA_3738 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285089.1 4153359 R 419947 CDS YP_001285090.1 148663567 5214484 complement(4154060..4155337) 1 NC_009525.1 hypothetical protein 4155337 5214484 MRA_3739 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285090.1 4154060 R 419947 CDS YP_001285091.1 148663568 5214779 complement(4155334..4156632) 1 NC_009525.1 glutamate--cysteine ligase 4156632 gshA 5214779 gshA Mycobacterium tuberculosis H37Ra glutamate--cysteine ligase YP_001285091.1 4155334 R 419947 CDS YP_001285092.1 148663569 5214780 complement(4156764..4157408) 1 NC_009525.1 hypothetical protein 4157408 5214780 MRA_3741 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285092.1 4156764 R 419947 CDS YP_001285093.1 148663570 5214781 complement(4157537..4157926) 1 NC_009525.1 hypothetical protein 4157926 5214781 MRA_3742 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285093.1 4157537 R 419947 CDS YP_001285094.1 148663571 5214782 complement(4158037..4158357) 1 NC_009525.1 hypothetical protein 4158357 5214782 MRA_3743 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285094.1 4158037 R 419947 CDS YP_001285095.1 148663572 5214783 complement(4158476..4159486) 1 NC_009525.1 hypothetical protein 4159486 5214783 MRA_3744 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285095.1 4158476 R 419947 CDS YP_001285096.1 148663573 5214784 complement(4159626..4160663) 1 NC_009525.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4160663 asd 5214784 asd Mycobacterium tuberculosis H37Ra aspartate-semialdehyde dehydrogenase YP_001285096.1 4159626 R 419947 CDS YP_001285097.1 148663574 5214785 complement(4160664..4161929) 1 NC_009525.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 4161929 ask 5214785 ask Mycobacterium tuberculosis H37Ra aspartate kinase YP_001285097.1 4160664 R 419947 CDS YP_001285098.1 148663575 5214786 4162186..4164120 1 NC_009525.1 2-isopropylmalate synthase 4164120 leuA 5214786 leuA Mycobacterium tuberculosis H37Ra 2-isopropylmalate synthase YP_001285098.1 4162186 D 419947 CDS YP_001285099.1 148663576 5214787 complement(4164186..4165175) 1 NC_009525.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 4165175 dnaQ 5214787 dnaQ Mycobacterium tuberculosis H37Ra DNA polymerase III subunit epsilon YP_001285099.1 4164186 R 419947 CDS YP_001285100.1 148663577 5214202 4165427..4166668 1 NC_009525.1 ligase 4166668 5214202 MRA_3749 Mycobacterium tuberculosis H37Ra ligase YP_001285100.1 4165427 D 419947 CDS YP_001285101.1 148663578 5214203 4166673..4167368 1 NC_009525.1 cobyric acid synthase 4167368 cobQ2 5214203 cobQ2 Mycobacterium tuberculosis H37Ra cobyric acid synthase YP_001285101.1 4166673 D 419947 CDS YP_001285102.1 148663579 5214204 complement(4167377..4168267) 1 NC_009525.1 hypothetical protein 4168267 5214204 MRA_3751 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285102.1 4167377 R 419947 CDS YP_001285103.1 148663580 5214205 complement(4168335..4168946) 1 NC_009525.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 4168946 recR 5214205 recR Mycobacterium tuberculosis H37Ra recombination protein RecR YP_001285103.1 4168335 R 419947 CDS YP_001285104.1 148663581 5214206 complement(4168958..4169359) 1 NC_009525.1 hypothetical protein 4169359 5214206 MRA_3753 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285104.1 4168958 R 419947 CDS YP_001285105.1 148663582 5214207 4169494..4170219 1 NC_009525.1 hypothetical protein 4170219 5214207 MRA_3754 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285105.1 4169494 D 419947 CDS YP_001285106.1 148663583 5214208 complement(4170261..4170704) 1 NC_009525.1 hypothetical protein 4170704 5214208 MRA_3755 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285106.1 4170261 R 419947 CDS YP_001285107.1 148663584 5214209 4170752..4172164 1 NC_009525.1 hypothetical protein 4172164 5214209 MRA_3756 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285107.1 4170752 D 419947 CDS YP_001285108.1 148663585 5214210 4172182..4173444 1 NC_009525.1 fatty acid synthase 4173444 5214210 MRA_3757 Mycobacterium tuberculosis H37Ra fatty acid synthase YP_001285108.1 4172182 D 419947 CDS YP_001285109.1 148663586 5212795 complement(4173441..4175177) 1 NC_009525.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 4175177 dnaZX 5212795 dnaZX Mycobacterium tuberculosis H37Ra DNA polymerase III subunits gamma and tau YP_001285109.1 4173441 R 419947 CDS YP_001285110.1 148663587 5212796 complement(4175267..4176574) 1 NC_009525.1 hypothetical protein 4176574 5212796 MRA_3759 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285110.1 4175267 R 419947 CDS YP_001285111.1 148663588 5212798 4176982..4177746 1 NC_009525.1 transmembrane protein 4177746 5212798 MRA_3760 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285111.1 4176982 D 419947 CDS YP_001285112.1 148663589 5212799 4177913..4178155 1 NC_009525.1 cutinase precursor Cut5a 4178155 cut5a 5212799 cut5a Mycobacterium tuberculosis H37Ra cutinase precursor Cut5a YP_001285112.1 4177913 D 419947 CDS YP_001285113.1 148663590 5212800 4178052..4178615 1 NC_009525.1 cutinase Cut5b 4178615 cut5b 5212800 cut5b Mycobacterium tuberculosis H37Ra cutinase Cut5b YP_001285113.1 4178052 D 419947 CDS YP_001285114.1 148663591 5212801 4178660..4179589 1 NC_009525.1 oxidoreductase 4179589 5212801 MRA_3763 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001285114.1 4178660 D 419947 CDS YP_001285115.1 148663592 5212802 4179867..4181060 1 NC_009525.1 dehydrogenase 4181060 5212802 MRA_3764 Mycobacterium tuberculosis H37Ra dehydrogenase YP_001285115.1 4179867 D 419947 CDS YP_001285116.1 148663593 5213098 4181401..4183209 1 NC_009525.1 oxidoreductase 4183209 5213098 MRA_3765 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001285116.1 4181401 D 419947 CDS YP_001285117.1 148663594 5213099 4183319..4186516 1 NC_009525.1 hypothetical protein 4186516 5213099 MRA_3766 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285117.1 4183319 D 419947 CDS YP_001285118.1 148663595 5213100 4186731..4189061 1 NC_009525.1 transferase 4189061 5213100 MRA_3767 Mycobacterium tuberculosis H37Ra transferase YP_001285118.1 4186731 D 419947 CDS YP_001285119.1 148663596 5213101 complement(4189126..4190166) 1 NC_009525.1 hypothetical protein 4190166 5213101 MRA_3768 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285119.1 4189126 R 419947 CDS YP_001285120.1 148663597 5213102 4190204..4191280 1 NC_009525.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; ATP-dependent DNA ligase 4191280 ligC 5213102 ligC Mycobacterium tuberculosis H37Ra ATP-dependent DNA ligase YP_001285120.1 4190204 D 419947 CDS YP_001285121.1 148663598 5213103 4191380..4192438 1 NC_009525.1 hypothetical protein 4192438 5213103 MRA_3770 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285121.1 4191380 D 419947 CDS YP_001285122.1 148663599 5213104 complement(4192458..4192958) 1 NC_009525.1 hypothetical protein 4192958 5213104 MRA_3771 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285122.1 4192458 R 419947 CDS YP_001285123.1 148663600 5213105 complement(4192972..4194336) 1 NC_009525.1 hypothetical protein 4194336 5213105 MRA_3772 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285123.1 4192972 R 419947 CDS YP_001285124.1 148663601 5213106 4194535..4195023 1 NC_009525.1 hypothetical protein 4195023 5213106 MRA_3773 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285124.1 4194535 D 419947 CDS YP_001285125.1 148663602 5214788 4195080..4196141 1 NC_009525.1 AraC family transcriptional regulator 4196141 5214788 MRA_3774 Mycobacterium tuberculosis H37Ra AraC family transcriptional regulator YP_001285125.1 4195080 D 419947 CDS YP_001285126.1 148663603 5214789 4196145..4197734 1 NC_009525.1 transmembrane protein 4197734 5214789 MRA_3775 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285126.1 4196145 D 419947 CDS YP_001285127.1 148663604 5214790 complement(4197731..4198678) 1 NC_009525.1 PPE family protein 4198678 5214790 MRA_3776 Mycobacterium tuberculosis H37Ra PPE family protein YP_001285127.1 4197731 R 419947 CDS YP_001285128.1 148663605 5214791 complement(4198730..4198963) 1 NC_009525.1 PPE family protein 4198963 5214791 MRA_3777 Mycobacterium tuberculosis H37Ra PPE family protein YP_001285128.1 4198730 R 419947 CDS YP_001285129.1 148663606 5214792 complement(4199279..4200625) 1 NC_009525.1 hypothetical protein 4200625 5214792 MRA_3778 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285129.1 4199279 R 419947 CDS YP_001285130.1 148663607 5214793 complement(4200625..4201299) 1 NC_009525.1 oxidoreductase 4201299 5214793 MRA_3779 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001285130.1 4200625 R 419947 CDS YP_001285131.1 148663608 5214794 complement(4201296..4201691) 1 NC_009525.1 oxidoreductase 4201691 5214794 MRA_3780 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001285131.1 4201296 R 419947 CDS YP_001285132.1 148663609 5214795 complement(4201837..4203819) 1 NC_009525.1 metal cation transporting P-type ATPase CtpJ 4203819 ctpJ 5214795 ctpJ Mycobacterium tuberculosis H37Ra metal cation transporting P-type ATPase CtpJ YP_001285132.1 4201837 R 419947 CDS YP_001285133.1 148663610 5214796 4203886..4204248 1 NC_009525.1 transcription regulator ArsR 4204248 5214796 MRA_3782 Mycobacterium tuberculosis H37Ra transcription regulator ArsR YP_001285133.1 4203886 D 419947 CDS YP_001285134.1 148663611 5211820 complement(4204332..4204544) 1 NC_009525.1 hypothetical protein 4204544 5211820 MRA_3783 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285134.1 4204332 R 419947 CDS YP_001285135.1 148663612 5211821 complement(4204617..4204952) 1 NC_009525.1 PE family protein 4204952 5211821 MRA_3784 Mycobacterium tuberculosis H37Ra PE family protein YP_001285135.1 4204617 R 419947 CDS YP_001285136.1 148663613 5211822 4205170..4205553 1 NC_009525.1 hypothetical protein 4205553 5211822 MRA_3785 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285136.1 4205170 D 419947 CDS YP_001285137.1 148663614 5211823 4205682..4206041 1 NC_009525.1 hypothetical protein 4206041 5211823 MRA_3786 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285137.1 4205682 D 419947 CDS YP_001285138.1 148663615 5211824 complement(4206074..4206583) 1 NC_009525.1 hypothetical protein 4206583 5211824 MRA_3787 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285138.1 4206074 R 419947 CDS YP_001285139.1 148663616 5211825 complement(4206651..4207043) 1 NC_009525.1 excisionase 4207043 5211825 MRA_3788 Mycobacterium tuberculosis H37Ra excisionase YP_001285139.1 4206651 R 419947 CDS YP_001285140.1 148663617 5211826 4207320..4207535 1 NC_009525.1 integrase 4207535 5211826 MRA_3789 Mycobacterium tuberculosis H37Ra integrase YP_001285140.1 4207320 D 419947 CDS YP_001285141.1 148663618 5211828 complement(4207693..4208151) 1 NC_009525.1 cytidine and deoxycytidylate deaminase 4208151 5211828 MRA_3790 Mycobacterium tuberculosis H37Ra cytidine and deoxycytidylate deaminase YP_001285141.1 4207693 R 419947 CDS YP_001285142.1 148663619 5212154 complement(4208167..4208667) 1 NC_009525.1 hypothetical protein 4208667 5212154 MRA_3791 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285142.1 4208167 R 419947 CDS YP_001285143.1 148663620 5212155 4208867..4209772 1 NC_009525.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 4209772 tyrA 5212155 tyrA Mycobacterium tuberculosis H37Ra prephenate dehydrogenase YP_001285143.1 4208867 D 419947 CDS YP_001285144.1 148663621 5212156 complement(4209735..4210334) 1 NC_009525.1 hypothetical protein 4210334 5212156 MRA_3793 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285144.1 4209735 R 419947 CDS YP_001285145.1 148663622 5212157 complement(4210340..4211059) 1 NC_009525.1 amino acid ABC transporter permease 4211059 proZ 5212157 proZ Mycobacterium tuberculosis H37Ra amino acid ABC transporter permease YP_001285145.1 4210340 R 419947 CDS YP_001285146.1 148663623 5212158 complement(4211056..4211745) 1 NC_009525.1 amino acid ABC transporter permease 4211745 proW 5212158 proW Mycobacterium tuberculosis H37Ra amino acid ABC transporter permease YP_001285146.1 4211056 R 419947 CDS YP_001285147.1 148663624 5212159 complement(4211733..4212863) 1 NC_009525.1 amino acid ABC transporter ATP-binding protein 4212863 proV 5212159 proV Mycobacterium tuberculosis H37Ra amino acid ABC transporter ATP-binding protein YP_001285147.1 4211733 R 419947 CDS YP_001285148.1 148663625 5212160 complement(4212872..4213819) 1 NC_009525.1 amino acid ABC transporter substrate-binding protein 4213819 proX 5212160 proX Mycobacterium tuberculosis H37Ra amino acid ABC transporter substrate-binding protein YP_001285148.1 4212872 R 419947 CDS YP_001285149.1 148663626 5212161 4213984..4214286 1 NC_009525.1 hypothetical protein 4214286 5212161 MRA_3798 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285149.1 4213984 D 419947 CDS YP_001285150.1 148663627 5212162 complement(4214308..4215363) 1 NC_009525.1 acyl-CoA dehydrogenase FadE36 4215363 fadE36 5212162 fadE36 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase FadE36 YP_001285150.1 4214308 R 419947 CDS YP_001285151.1 148663628 5212163 complement(4215442..4217322) 1 NC_009525.1 hydrolase 4217322 5212163 MRA_3800 Mycobacterium tuberculosis H37Ra hydrolase YP_001285151.1 4215442 R 419947 CDS YP_001285152.1 148663629 5213843 4217493..4217972 1 NC_009525.1 lipoprotein LpqH 4217972 lpqH 5213843 lpqH Mycobacterium tuberculosis H37Ra lipoprotein LpqH YP_001285152.1 4217493 D 419947 CDS YP_001285153.1 148663630 5213844 complement(4218028..4219455) 1 NC_009525.1 two component sensor kinase 4219455 5213844 MRA_3802 Mycobacterium tuberculosis H37Ra two component sensor kinase YP_001285153.1 4218028 R 419947 CDS YP_001285154.1 148663631 5213845 complement(4219526..4220230) 1 NC_009525.1 DNA-binding response regulator 4220230 5213845 MRA_3803 Mycobacterium tuberculosis H37Ra DNA-binding response regulator YP_001285154.1 4219526 R 419947 CDS YP_001285155.1 148663632 5213846 4220739..4221428 1 NC_009525.1 hypothetical protein 4221428 5213846 MRA_3804 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285155.1 4220739 D 419947 CDS YP_001285156.1 148663633 5213847 complement(4221442..4222386) 1 NC_009525.1 hypothetical protein 4222386 5213847 MRA_3805 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285156.1 4221442 R 419947 CDS YP_001285157.1 148663634 5213848 4222516..4222875 1 NC_009525.1 hypothetical protein 4222875 5213848 MRA_3806 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285157.1 4222516 D 419947 CDS YP_001285158.1 148663635 5213849 4223061..4223333 1 NC_009525.1 hypothetical protein 4223333 5213849 MRA_3807 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285158.1 4223061 D 419947 CDS YP_001285159.1 148663636 5213850 complement(4223646..4224221) 1 NC_009525.1 hypothetical protein 4224221 5213850 MRA_3808 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285159.1 4223646 R 419947 CDS YP_001285160.1 148663637 5213851 complement(4224327..4224509) 1 NC_009525.1 remnant of a transposase 4224509 5213851 MRA_3809 Mycobacterium tuberculosis H37Ra remnant of a transposase YP_001285160.1 4224327 R 419947 CDS YP_001285161.1 148663638 5213852 complement(4224524..4224715) 1 NC_009525.1 remnant of a transposase 4224715 5213852 MRA_3810 Mycobacterium tuberculosis H37Ra remnant of a transposase YP_001285161.1 4224524 R 419947 CDS YP_001285162.1 148663639 5214081 complement(4224850..4225176) 1 NC_009525.1 hypothetical protein 4225176 5214081 MRA_3811 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285162.1 4224850 R 419947 CDS YP_001285163.1 148663640 5214084 4225580..4226641 1 NC_009525.1 aminotransferase 4226641 hisC2 5214084 hisC2 Mycobacterium tuberculosis H37Ra aminotransferase YP_001285163.1 4225580 D 419947 CDS YP_001285164.1 148663641 5214085 complement(4226687..4227271) 1 NC_009525.1 hypothetical protein 4227271 5214085 MRA_3813 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285164.1 4226687 R 419947 CDS YP_001285165.1 148663642 5214086 4227295..4228119 1 NC_009525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4228119 echA21 5214086 echA21 Mycobacterium tuberculosis H37Ra enoyl-CoA hydratase YP_001285165.1 4227295 D 419947 CDS YP_001285166.1 148663643 5214087 4228131..4229378 1 NC_009525.1 lipase LipE 4229378 lipE 5214087 lipE Mycobacterium tuberculosis H37Ra lipase LipE YP_001285166.1 4228131 D 419947 CDS YP_001285167.1 148663644 5214095 4229535..4231094 1 NC_009525.1 hypothetical protein 4231094 5214095 MRA_3816 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285167.1 4229535 D 419947 CDS YP_001285168.1 148663645 5214097 4231140..4232126 1 NC_009525.1 oxidoreductase 4232126 5214097 MRA_3817 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001285168.1 4231140 D 419947 CDS YP_001285169.1 148663646 5214098 complement(4232145..4233341) 1 NC_009525.1 aminotransferase 4233341 5214098 MRA_3818 Mycobacterium tuberculosis H37Ra aminotransferase YP_001285169.1 4232145 R 419947 CDS YP_001285170.1 148663647 5214099 4233431..4235431 1 NC_009525.1 alanine and leucine rich transmembrane protein 4235431 5214099 MRA_3819 Mycobacterium tuberculosis H37Ra alanine and leucine rich transmembrane protein YP_001285170.1 4233431 D 419947 CDS YP_001285171.1 148663648 5214100 4235435..4235971 1 NC_009525.1 hypothetical protein 4235971 5214100 MRA_3820 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285171.1 4235435 D 419947 CDS YP_001285172.1 148663649 5214101 4235975..4236796 1 NC_009525.1 O-antigen/lipopolysaccharide ABC transporter ATP-binding protein RfbE 4236796 rfbE 5214101 rfbE Mycobacterium tuberculosis H37Ra O-antigen/lipopolysaccharide ABC transporter ATP-binding protein RfbE YP_001285172.1 4235975 D 419947 CDS YP_001285173.1 148663650 5214102 4236793..4237707 1 NC_009525.1 glycosyl transferase 4237707 5214102 MRA_3822 Mycobacterium tuberculosis H37Ra glycosyl transferase YP_001285173.1 4236793 D 419947 CDS YP_001285174.1 148663651 5214529 4237704..4238546 1 NC_009525.1 O-antigen/lipopolysaccharide ABC transporter permease RfbD 4238546 rfbD 5214529 rfbD Mycobacterium tuberculosis H37Ra O-antigen/lipopolysaccharide ABC transporter permease RfbD YP_001285174.1 4237704 D 419947 CDS YP_001285175.1 148663652 5214530 4238702..4239682 1 NC_009525.1 dTDP-glucose 4,6-dehydratase 4239682 5214530 MRA_3824 Mycobacterium tuberculosis H37Ra dTDP-glucose 4,6-dehydratase YP_001285175.1 4238702 D 419947 CDS YP_001285176.1 148663653 5214531 4239766..4240839 1 NC_009525.1 hypothetical protein 4240839 5214531 MRA_3825 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285176.1 4239766 D 419947 CDS YP_001285177.1 148663654 5214532 complement(4240820..4242043) 1 NC_009525.1 hypothetical protein 4242043 5214532 MRA_3826 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285177.1 4240820 R 419947 CDS YP_001285178.1 148663655 5214533 complement(4242056..4242982) 1 NC_009525.1 hypothetical protein 4242982 5214533 MRA_3827 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285178.1 4242056 R 419947 CDS YP_001285179.1 148663656 5214534 4243226..4243711 1 NC_009525.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 4243711 5214534 MRA_3828 Mycobacterium tuberculosis H37Ra nucleoside diphosphate kinase regulator YP_001285179.1 4243226 D 419947 CDS YP_001285180.1 148663657 5214535 4243820..4244185 1 NC_009525.1 hypothetical protein 4244185 5214535 MRA_3829 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285180.1 4243820 D 419947 CDS YP_001285181.1 148663658 5214536 4244225..4245610 1 NC_009525.1 oxidoreductase 4245610 5214536 MRA_3830 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001285181.1 4244225 D 419947 CDS YP_001285182.1 148663659 5214537 4245611..4246375 1 NC_009525.1 short chain dehydrogenase 4246375 5214537 MRA_3831 Mycobacterium tuberculosis H37Ra short chain dehydrogenase YP_001285182.1 4245611 D 419947 CDS YP_001285183.1 148663660 5214538 4246378..4248309 1 NC_009525.1 transmembrane protein 4248309 5214538 MRA_3832 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285183.1 4246378 D 419947 CDS YP_001285184.1 148663661 5212036 4248309..4251593 1 NC_009525.1 arabinosyl transferase C 4251593 embC 5212036 embC Mycobacterium tuberculosis H37Ra arabinosyl transferase C YP_001285184.1 4248309 D 419947 CDS YP_001285185.1 148663662 5212037 4251679..4254963 1 NC_009525.1 arabinosyl transferase A 4254963 embA 5212037 embA Mycobacterium tuberculosis H37Ra arabinosyl transferase A YP_001285185.1 4251679 D 419947 CDS YP_001285186.1 148663663 5212038 4254960..4258256 1 NC_009525.1 arabinosyl transferase B 4258256 embB 5212038 embB Mycobacterium tuberculosis H37Ra arabinosyl transferase B YP_001285186.1 4254960 D 419947 CDS YP_001285187.1 148663664 5212039 4258324..4259451 1 NC_009525.1 hypothetical protein 4259451 5212039 MRA_3836 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285187.1 4258324 D 419947 CDS YP_001285188.1 148663665 5212040 4259531..4261312 1 NC_009525.1 acyl-CoA dehydrogenase 4261312 fadE35 5212040 fadE35 Mycobacterium tuberculosis H37Ra acyl-CoA dehydrogenase YP_001285188.1 4259531 D 419947 CDS YP_001285189.1 148663666 5212041 4261439..4262773 1 NC_009525.1 transposase 4262773 5212041 MRA_3838 Mycobacterium tuberculosis H37Ra transposase YP_001285189.1 4261439 D 419947 CDS YP_001285190.1 148663667 5212042 complement(4262826..4264394) 1 NC_009525.1 propionyl-CoA carboxylase subunit beta 4264394 accD4 5212042 accD4 Mycobacterium tuberculosis H37Ra propionyl-CoA carboxylase subunit beta YP_001285190.1 4262826 R 419947 CDS YP_001285191.1 148663668 5212043 complement(4264391..4269592) 1 NC_009525.1 polyketide synthase 4269592 pks13 5212043 pks13 Mycobacterium tuberculosis H37Ra polyketide synthase YP_001285191.1 4264391 R 419947 CDS YP_001285192.1 148663669 5212044 complement(4269599..4271512) 1 NC_009525.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 4271512 fadD32 5212044 fadD32 Mycobacterium tuberculosis H37Ra long-chain-fatty-acid--CoA ligase YP_001285192.1 4269599 R 419947 CDS YP_001285193.1 148663670 5212045 complement(4271801..4272811) 1 NC_009525.1 hypothetical protein 4272811 5212045 MRA_3842 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285193.1 4271801 R 419947 CDS YP_001285194.1 148663671 5214566 complement(4273009..4273908) 1 NC_009525.1 secreted mpt51/mpb51 antigen protein FbpD 4273908 fbpD 5214566 fbpD Mycobacterium tuberculosis H37Ra secreted mpt51/mpb51 antigen protein FbpD YP_001285194.1 4273009 R 419947 CDS YP_001285195.1 148663672 5214567 complement(4274088..4275104) 1 NC_009525.1 secreted antigen 85-A FbpA 4275104 fbpA 5214567 fbpA Mycobacterium tuberculosis H37Ra secreted antigen 85-A FbpA YP_001285195.1 4274088 R 419947 CDS YP_001285196.1 148663673 5214568 complement(4275399..4277282) 1 NC_009525.1 transmembrane protein 4277282 5214568 MRA_3845 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285196.1 4275399 R 419947 CDS YP_001285197.1 148663674 5214569 complement(4277371..4278279) 1 NC_009525.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase 4278279 5214569 MRA_3846 Mycobacterium tuberculosis H37Ra phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase YP_001285197.1 4277371 R 419947 CDS YP_001285198.1 148663675 5214570 complement(4278286..4278783) 1 NC_009525.1 transmembrane protein 4278783 5214570 MRA_3847 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285198.1 4278286 R 419947 CDS YP_001285199.1 148663676 5214571 complement(4278812..4280725) 1 NC_009525.1 bifunctional udp-galactofuranosyl transferase 4280725 glfT 5214571 glfT Mycobacterium tuberculosis H37Ra bifunctional udp-galactofuranosyl transferase YP_001285199.1 4278812 R 419947 CDS YP_001285200.1 148663677 5214572 complement(4280722..4281921) 1 NC_009525.1 UDP-galactopyranose mutase 4281921 glf 5214572 glf Mycobacterium tuberculosis H37Ra UDP-galactopyranose mutase YP_001285200.1 4280722 R 419947 CDS YP_001285201.1 148663678 5214573 4282185..4283039 1 NC_009525.1 exported repetitive protein precursor PirG 4283039 pirG 5214573 pirG Mycobacterium tuberculosis H37Ra exported repetitive protein precursor PirG YP_001285201.1 4282185 D 419947 CDS YP_001285202.1 148663679 5214574 4283244..4284863 1 NC_009525.1 hypothetical protein 4284863 5214574 MRA_3851 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285202.1 4283244 D 419947 CDS YP_001285203.1 148663680 5214575 4285017..4286531 1 NC_009525.1 PE-PGRS family protein 4286531 5214575 MRA_3852 Mycobacterium tuberculosis H37Ra PE-PGRS family protein YP_001285203.1 4285017 D 419947 CDS YP_001285204.1 148663681 5214256 complement(4286840..4287661) 1 NC_009525.1 hypothetical protein 4287661 5214256 MRA_3853 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285204.1 4286840 R 419947 CDS YP_001285205.1 148663682 5214257 complement(4287676..4288461) 1 NC_009525.1 acyltransferase 4288461 5214257 MRA_3854 Mycobacterium tuberculosis H37Ra acyltransferase YP_001285205.1 4287676 R 419947 CDS YP_001285206.1 148663683 5214258 complement(4288479..4289234) 1 NC_009525.1 acyltransferase 4289234 5214258 MRA_3855 Mycobacterium tuberculosis H37Ra acyltransferase YP_001285206.1 4288479 R 419947 CDS YP_001285207.1 148663684 5214259 complement(4289238..4290017) 1 NC_009525.1 acyltransferase 4290017 5214259 MRA_3856 Mycobacterium tuberculosis H37Ra acyltransferase YP_001285207.1 4289238 R 419947 CDS YP_001285208.1 148663685 5214260 4290093..4290848 1 NC_009525.1 aminoglycoside 3-N-acetyltransferase 4290848 aph 5214260 aph Mycobacterium tuberculosis H37Ra aminoglycoside 3-N-acetyltransferase YP_001285208.1 4290093 D 419947 CDS YP_001285209.1 148663686 5214261 4290895..4292445 1 NC_009525.1 hypothetical protein 4292445 5214261 MRA_3858 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285209.1 4290895 D 419947 CDS YP_001285210.1 148663687 5214262 4292442..4292777 1 NC_009525.1 hypothetical protein 4292777 5214262 MRA_3859 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285210.1 4292442 D 419947 CDS YP_001285211.1 148663688 5214263 complement(4292865..4294271) 1 NC_009525.1 polyketide synthase associated protein PapA2 4294271 papA2 5214263 papA2 Mycobacterium tuberculosis H37Ra polyketide synthase associated protein PapA2 YP_001285211.1 4292865 R 419947 CDS YP_001285212.1 148663689 5214264 4294419..4295132 1 NC_009525.1 hypothetical protein 4295132 5214264 MRA_3861 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285212.1 4294419 D 419947 CDS YP_001285213.1 148663690 5214265 4295167..4296381 1 NC_009525.1 hypothetical protein 4296381 5214265 MRA_3862 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285213.1 4295167 D 419947 CDS YP_001285214.1 148663691 5214944 complement(4296706..4299975) 1 NC_009525.1 transmembrane transport protein MmpL8 4299975 mmpL8 5214944 mmpL8 Mycobacterium tuberculosis H37Ra transmembrane transport protein MmpL8 YP_001285214.1 4296706 R 419947 CDS YP_001285215.1 148663692 5214945 complement(4300085..4301620) 1 NC_009525.1 polyketide synthase associated protein PapA1 4301620 papA1 5214945 papA1 Mycobacterium tuberculosis H37Ra polyketide synthase associated protein PapA1 YP_001285215.1 4300085 R 419947 CDS YP_001285216.1 148663693 5214946 complement(4301671..4308051) 1 NC_009525.1 polyketide synthase 4308051 pks2 5214946 pks2 Mycobacterium tuberculosis H37Ra polyketide synthase YP_001285216.1 4301671 R 419947 CDS YP_001285217.1 148663694 5214947 4308258..4310012 1 NC_009525.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 4310012 fadD23 5214947 fadD23 Mycobacterium tuberculosis H37Ra acyl-CoA synthetase YP_001285217.1 4308258 D 419947 CDS YP_001285218.1 148663695 5214948 complement(4310009..4311235) 1 NC_009525.1 IS1537 transposase 4311235 5214948 MRA_3867 Mycobacterium tuberculosis H37Ra IS1537 transposase YP_001285218.1 4310009 R 419947 CDS YP_001285219.1 148663696 5214949 complement(4311232..4311843) 1 NC_009525.1 IS1537 resolvase 4311843 5214949 MRA_3868 Mycobacterium tuberculosis H37Ra IS1537 resolvase YP_001285219.1 4311232 R 419947 CDS YP_001285220.1 148663697 5214950 complement(4311844..4313454) 1 NC_009525.1 oxidoreductase 4313454 5214950 MRA_3869 Mycobacterium tuberculosis H37Ra oxidoreductase YP_001285220.1 4311844 R 419947 CDS YP_001285221.1 148663698 5214951 complement(4313502..4314131) 1 NC_009525.1 TetR family transcriptional regulator 4314131 5214951 MRA_3870 Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001285221.1 4313502 R 419947 CDS YP_001285222.1 148663699 5214952 4314203..4314685 1 NC_009525.1 hypothetical protein 4314685 5214952 MRA_3871 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285222.1 4314203 D 419947 CDS YP_001285223.1 148663700 5214953 complement(4314682..4315257) 1 NC_009525.1 hypothetical protein 4315257 5214953 MRA_3872 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285223.1 4314682 R 419947 CDS YP_001285224.1 148663701 5211929 4315313..4316104 1 NC_009525.1 AraC family transcriptional regulator 4316104 5211929 MRA_3873 Mycobacterium tuberculosis H37Ra AraC family transcriptional regulator YP_001285224.1 4315313 D 419947 CDS YP_001285225.1 148663702 5211930 complement(4316101..4317360) 1 NC_009525.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 4317360 serS 5211930 serS Mycobacterium tuberculosis H37Ra seryl-tRNA synthetase YP_001285225.1 4316101 R 419947 CDS YP_001285226.1 148663703 5211931 4317493..4318842 1 NC_009525.1 hypothetical protein 4318842 5211931 MRA_3875 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285226.1 4317493 D 419947 CDS YP_001285227.1 148663704 5211932 4318847..4319260 1 NC_009525.1 hypothetical protein 4319260 5211932 MRA_3876 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285227.1 4318847 D 419947 CDS YP_001285228.1 148663705 5211933 complement(4319455..4320153) 1 NC_009525.1 phosphoglycerate mutase 4320153 5211933 MRA_3877 Mycobacterium tuberculosis H37Ra phosphoglycerate mutase YP_001285228.1 4319455 R 419947 CDS YP_001285229.1 148663706 5211934 complement(4320150..4321115) 1 NC_009525.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 4321115 pheA 5211934 pheA Mycobacterium tuberculosis H37Ra prephenate dehydratase YP_001285229.1 4320150 R 419947 CDS YP_001285230.1 148663707 5211935 4321211..4321987 1 NC_009525.1 hypothetical protein 4321987 5211935 MRA_3879 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285230.1 4321211 D 419947 CDS YP_001285231.1 148663708 5211936 4322013..4322426 1 NC_009525.1 transcriptional regulatory protein 4322426 5211936 MRA_3880 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein YP_001285231.1 4322013 D 419947 CDS YP_001285232.1 148663709 5211937 4322624..4323169 1 NC_009525.1 ferritin 4323169 bfrB 5211937 bfrB Mycobacterium tuberculosis H37Ra ferritin YP_001285232.1 4322624 D 419947 CDS YP_001285233.1 148663710 5211938 complement(4323184..4324008) 1 NC_009525.1 glycerophosphoryl diester phosphodiesterase 4324008 glpQ1 5211938 glpQ1 Mycobacterium tuberculosis H37Ra glycerophosphoryl diester phosphodiesterase YP_001285233.1 4323184 R 419947 CDS YP_001285234.1 148663711 5213870 complement(4324014..4325042) 1 NC_009525.1 transmembrane protein 4325042 5213870 MRA_3883 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285234.1 4324014 R 419947 CDS YP_001285235.1 148663712 5213871 4327221..4327712 1 NC_009525.1 transposase 4327712 5213871 MRA_3884 Mycobacterium tuberculosis H37Ra transposase YP_001285235.1 4327221 D 419947 CDS YP_001285236.1 148663713 5213872 4327727..4328086 1 NC_009525.1 hypothetical protein 4328086 5213872 MRA_3885 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285236.1 4327727 D 419947 CDS YP_001285237.1 148663714 5213873 4329150..4329773 1 NC_009525.1 superoxide dismutase 4329773 sodA 5213873 sodA Mycobacterium tuberculosis H37Ra superoxide dismutase YP_001285237.1 4329150 D 419947 CDS YP_001285238.1 148663715 5213874 4329984..4330517 1 NC_009525.1 hypothetical protein 4330517 5213874 MRA_3887 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285238.1 4329984 D 419947 CDS YP_001285239.1 148663716 5213875 4330772..4331680 1 NC_009525.1 transmembrane protein 4331680 5213875 MRA_3888 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285239.1 4330772 D 419947 CDS YP_001285240.1 148663717 5213876 4331945..4332343 1 NC_009525.1 hypothetical protein 4332343 5213876 MRA_3889 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285240.1 4331945 D 419947 CDS YP_001285241.1 148663718 5213877 4332461..4333117 1 NC_009525.1 hypothetical protein 4333117 5213877 MRA_3890 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285241.1 4332461 D 419947 CDS YP_001285242.1 148663719 5213878 4333129..4333413 1 NC_009525.1 hypothetical protein 4333413 5213878 MRA_3891 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285242.1 4333129 D 419947 CDS YP_001285243.1 148663720 5213879 4333520..4333924 1 NC_009525.1 histone-like protein Hns 4333924 hns 5213879 hns Mycobacterium tuberculosis H37Ra histone-like protein Hns YP_001285243.1 4333520 D 419947 CDS YP_001285244.1 148663721 5212702 4333941..4334414 1 NC_009525.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4334414 menG 5212702 menG Mycobacterium tuberculosis H37Ra ribonuclease activity regulator protein RraA YP_001285244.1 4333941 D 419947 CDS YP_001285245.1 148663722 5212703 complement(4334450..4335919) 1 NC_009525.1 monooxygenase EthA 4335919 ethA 5212703 ethA Mycobacterium tuberculosis H37Ra monooxygenase EthA YP_001285245.1 4334450 R 419947 CDS YP_001285246.1 148663723 5212704 4335995..4336645 1 NC_009525.1 TetR family transcriptional regulator 4336645 ethR 5212704 ethR Mycobacterium tuberculosis H37Ra TetR family transcriptional regulator YP_001285246.1 4335995 D 419947 CDS YP_001285247.1 148663724 5212705 complement(4336847..4337854) 1 NC_009525.1 hypothetical protein 4337854 5212705 MRA_3896 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285247.1 4336847 R 419947 CDS YP_001285248.1 148663725 5212706 complement(4337863..4338060) 1 NC_009525.1 hypothetical protein 4338060 5212706 MRA_3897 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285248.1 4337863 R 419947 CDS YP_001285249.1 148663726 5212707 complement(4338485..4339951) 1 NC_009525.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 4339951 gltD 5212707 gltD Mycobacterium tuberculosis H37Ra glutamate synthase subunit beta YP_001285249.1 4338485 R 419947 CDS YP_001285250.1 148663727 5212708 complement(4339944..4344527) 1 NC_009525.1 glutamate synthase large subunit 4344527 gltB 5212708 gltB Mycobacterium tuberculosis H37Ra glutamate synthase large subunit YP_001285250.1 4339944 R 419947 CDS YP_001285251.1 148663728 5212709 4345223..4346395 1 NC_009525.1 hypothetical protein 4346395 5212709 MRA_3900 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285251.1 4345223 D 419947 CDS YP_001285252.1 148663729 5212710 complement(4346617..4346967) 1 NC_009525.1 transcriptional regulatory protein whib-like WhiB6 4346967 whiB6 5212710 whiB6 Mycobacterium tuberculosis H37Ra transcriptional regulatory protein whib-like WhiB6 YP_001285252.1 4346617 R 419947 CDS YP_001285253.1 148663730 5212711 4347295..4348473 1 NC_009525.1 hypothetical protein 4348473 5212711 MRA_3902 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285253.1 4347295 D 419947 CDS YP_001285254.1 148663731 5212812 4348716..4349924 1 NC_009525.1 hypothetical protein 4349924 5212812 MRA_3903 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285254.1 4348716 D 419947 CDS YP_001285255.1 148663732 5212813 4350012..4350323 1 NC_009525.1 hypothetical protein 4350323 5212813 MRA_3904 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285255.1 4350012 D 419947 CDS YP_001285256.1 148663733 5212814 4350326..4351177 1 NC_009525.1 hypothetical protein 4351177 5212814 MRA_3905 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285256.1 4350326 D 419947 CDS YP_001285257.1 148663734 5212815 4351216..4351767 1 NC_009525.1 hypothetical protein 4351767 5212815 MRA_3906 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285257.1 4351216 D 419947 CDS YP_001285258.1 148663735 5212816 4351760..4353481 1 NC_009525.1 hypothetical protein 4353481 5212816 MRA_3907 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285258.1 4351760 D 419947 CDS YP_001285259.1 148663736 5212817 4353485..4354927 1 NC_009525.1 hypothetical protein 4354927 5212817 MRA_3908 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285259.1 4353485 D 419947 CDS YP_001285260.1 148663737 5212818 4354927..4357170 1 NC_009525.1 transmembrane protein 4357170 5212818 MRA_3909 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285260.1 4354927 D 419947 CDS YP_001285261.1 148663738 5212819 4357273..4359048 1 NC_009525.1 hypothetical protein 4359048 5212819 MRA_3910 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285261.1 4357273 D 419947 CDS YP_001285262.1 148663739 5212820 4359191..4359490 1 NC_009525.1 PPE family protein 4359490 5212820 MRA_3911 Mycobacterium tuberculosis H37Ra PPE family protein YP_001285262.1 4359191 D 419947 CDS YP_001285263.1 148663740 5212821 4359521..4360627 1 NC_009525.1 PPE family protein 4360627 5212821 MRA_3912 Mycobacterium tuberculosis H37Ra PPE family protein YP_001285263.1 4359521 D 419947 CDS YP_001285264.1 148663741 5214548 4360720..4361022 1 NC_009525.1 antigen EsxB 4361022 esxB 5214548 esxB Mycobacterium tuberculosis H37Ra antigen EsxB YP_001285264.1 4360720 D 419947 CDS YP_001285265.1 148663742 5214549 4361055..4361342 1 NC_009525.1 early secretory antigenic target EsxA 4361342 esxA 5214549 esxA Mycobacterium tuberculosis H37Ra early secretory antigenic target EsxA YP_001285265.1 4361055 D 419947 CDS YP_001285266.1 148663743 5214550 4361456..4363456 1 NC_009525.1 hypothetical protein 4363456 5214550 MRA_3915 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285266.1 4361456 D 419947 CDS YP_001285267.1 148663744 5214551 4363453..4364988 1 NC_009525.1 transmembrane protein 4364988 5214551 MRA_3916 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285267.1 4363453 D 419947 CDS YP_001285268.1 148663745 5214552 4365139..4365981 1 NC_009525.1 hypothetical protein 4365981 5214552 MRA_3917 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285268.1 4365139 D 419947 CDS YP_001285269.1 148663746 5214553 complement(4366039..4368228) 1 NC_009525.1 hypothetical protein 4368228 5214553 MRA_3918 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285269.1 4366039 R 419947 CDS YP_001285270.1 148663747 5214554 complement(4368645..4368992) 1 NC_009525.1 hypothetical protein 4368992 5214554 MRA_3919 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285270.1 4368645 R 419947 CDS YP_001285271.1 148663748 5214555 complement(4368989..4370371) 1 NC_009525.1 hypothetical protein 4370371 5214555 MRA_3920 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285271.1 4368989 R 419947 CDS YP_001285272.1 148663749 5214556 complement(4370478..4371866) 1 NC_009525.1 hypothetical protein 4371866 5214556 MRA_3921 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285272.1 4370478 R 419947 CDS YP_001285273.1 148663750 5214557 complement(4371863..4373203) 1 NC_009525.1 membrane-anchored mycosin Mycp1 4373203 mycP1 5214557 mycP1 Mycobacterium tuberculosis H37Ra membrane-anchored mycosin Mycp1 YP_001285273.1 4371863 R 419947 CDS YP_001285274.1 148663751 5214754 complement(4373425..4375284) 1 NC_009525.1 CbxX/CfqX family protein 4375284 5214754 MRA_3923 Mycobacterium tuberculosis H37Ra CbxX/CfqX family protein YP_001285274.1 4373425 R 419947 CDS YP_001285275.1 148663752 5214755 complement(4375354..4376967) 1 NC_009525.1 hypothetical protein 4376967 5214755 MRA_3924 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285275.1 4375354 R 419947 CDS YP_001285276.1 148663753 5214756 complement(4376964..4378616) 1 NC_009525.1 serine protease; alanine and proline rich membrane-anchored mycosin MycP2 4378616 mycP2 5214756 mycP2 Mycobacterium tuberculosis H37Ra alanine and proline rich membrane-anchored mycosin MycP2 YP_001285276.1 4376964 R 419947 CDS YP_001285277.1 148663754 5214757 complement(4378601..4380130) 1 NC_009525.1 transmembrane protein 4380130 5214757 MRA_3926 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285277.1 4378601 R 419947 CDS YP_001285278.1 148663755 5214758 complement(4380127..4381152) 1 NC_009525.1 hypothetical protein 4381152 5214758 MRA_3927 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285278.1 4380127 R 419947 CDS YP_001285279.1 148663756 5214759 complement(4381246..4382076) 1 NC_009525.1 hypothetical protein 4382076 5214759 MRA_3928 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285279.1 4381246 R 419947 CDS YP_001285280.1 148663757 5214760 complement(4382172..4382459) 1 NC_009525.1 esat-6 like protein EsxC 4382459 esxC 5214760 esxC Mycobacterium tuberculosis H37Ra esat-6 like protein EsxC YP_001285280.1 4382172 R 419947 CDS YP_001285281.1 148663758 5214761 complement(4382495..4382818) 1 NC_009525.1 esat-6 like protein EsxD 4382818 esxD 5214761 esxD Mycobacterium tuberculosis H37Ra esat-6 like protein EsxD YP_001285281.1 4382495 R 419947 CDS YP_001285282.1 148663759 5214762 complement(4382930..4384129) 1 NC_009525.1 PPE family protein 4384129 5214762 MRA_3931 Mycobacterium tuberculosis H37Ra PPE family protein YP_001285282.1 4382930 R 419947 CDS YP_001285283.1 148663760 5214763 complement(4384208..4384441) 1 NC_009525.1 PE family protein 4384441 5214763 MRA_3932 Mycobacterium tuberculosis H37Ra PE family protein YP_001285283.1 4384208 R 419947 CDS YP_001285284.1 148663761 5212026 complement(4384708..4388898) 1 NC_009525.1 hypothetical protein 4388898 5212026 MRA_3933 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285284.1 4384708 R 419947 CDS YP_001285285.1 148663762 5212027 complement(4388899..4390386) 1 NC_009525.1 hypothetical protein 4390386 5212027 MRA_3934 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285285.1 4388899 R 419947 CDS YP_001285286.1 148663763 5212028 complement(4390389..4391297) 1 NC_009525.1 hypothetical protein 4391297 5212028 MRA_3935 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285286.1 4390389 R 419947 CDS YP_001285287.1 148663764 5212029 complement(4391454..4392086) 1 NC_009525.1 hypothetical protein 4392086 5212029 MRA_3936 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285287.1 4391454 R 419947 CDS YP_001285288.1 148663765 5212030 complement(4392099..4392431) 1 NC_009525.1 hypothetical protein 4392431 5212030 MRA_3937 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285288.1 4392099 R 419947 CDS YP_001285289.1 148663766 5212031 complement(4392593..4393825) 1 NC_009525.1 hypothetical protein 4393825 5212031 MRA_3938 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285289.1 4392593 R 419947 CDS YP_001285290.1 148663767 5212032 complement(4393819..4394754) 1 NC_009525.1 hypothetical protein 4394754 5212032 MRA_3939 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285290.1 4393819 R 419947 CDS YP_001285291.1 148663768 5212033 complement(4394811..4395260) 1 NC_009525.1 hypothetical protein 4395260 5212033 MRA_3940 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285291.1 4394811 R 419947 CDS YP_001285292.1 148663769 5212034 complement(4395811..4396341) 1 NC_009525.1 hypothetical protein 4396341 5212034 MRA_3941 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285292.1 4395811 R 419947 CDS YP_001285293.1 148663770 5212035 complement(4396338..4398878) 1 NC_009525.1 hypothetical protein 4398878 5212035 MRA_3942 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285293.1 4396338 R 419947 CDS YP_001285294.1 148663771 5214797 complement(4398883..4399155) 1 NC_009525.1 esat-6 like protein EsxE 4399155 esxE 5214797 esxE Mycobacterium tuberculosis H37Ra esat-6 like protein EsxE YP_001285294.1 4398883 R 419947 CDS YP_001285295.1 148663772 5214798 complement(4399166..4399477) 1 NC_009525.1 esat-6 like protein EsxF 4399477 esxF 5214798 esxF Mycobacterium tuberculosis H37Ra esat-6 like protein EsxF YP_001285295.1 4399166 R 419947 CDS YP_001285296.1 148663773 5214799 complement(4399543..4400052) 1 NC_009525.1 hypothetical protein 4400052 5214799 MRA_3945 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285296.1 4399543 R 419947 CDS YP_001285297.1 148663774 5214800 complement(4400077..4401519) 1 NC_009525.1 poly(A) polymerase 4401519 pcnA 5214800 pcnA Mycobacterium tuberculosis H37Ra poly(A) polymerase YP_001285297.1 4400077 R 419947 CDS YP_001285298.1 148663775 5214801 4401895..4402641 1 NC_009525.1 hypothetical protein 4402641 5214801 MRA_3947 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285298.1 4401895 D 419947 CDS YP_001285299.1 148663776 5214802 4402638..4405046 1 NC_009525.1 hypothetical protein 4405046 5214802 MRA_3948 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285299.1 4402638 D 419947 CDS YP_001285300.1 148663777 5214803 4405043..4408597 1 NC_009525.1 transmembrane protein 4408597 5214803 MRA_3949 Mycobacterium tuberculosis H37Ra transmembrane protein YP_001285300.1 4405043 D 419947 CDS YP_001285301.1 148663778 5214804 4408632..4409222 1 NC_009525.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase; RNA polymerase sigma factor SigM 4409222 sigM 5214804 sigM Mycobacterium tuberculosis H37Ra RNA polymerase sigma factor SigM YP_001285301.1 4408632 D 419947 CDS YP_001285302.1 148663779 5214805 4409315..4410079 1 NC_009525.1 hypothetical protein 4410079 5214805 MRA_3951 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285302.1 4409315 D 419947 CDS YP_001285303.1 148663780 5214806 4410173..4411180 1 NC_009525.1 thioredoxin reductase TrxB2 4411180 trxB2 5214806 trxB2 Mycobacterium tuberculosis H37Ra thioredoxin reductase TrxB2 YP_001285303.1 4410173 D 419947 CDS YP_001285304.1 148663781 5212392 4411177..4411527 1 NC_009525.1 thioredoxin TrxC 4411527 trxC 5212392 trxC Mycobacterium tuberculosis H37Ra thioredoxin TrxC YP_001285304.1 4411177 D 419947 CDS YP_001285305.1 148663782 5212393 4411637..4412857 1 NC_009525.1 N-acetymuramyl-L-alanine amidase-related protein 4412857 5212393 MRA_3954 Mycobacterium tuberculosis H37Ra N-acetymuramyl-L-alanine amidase-related protein YP_001285305.1 4411637 D 419947 CDS YP_001285306.1 148663783 5212394 complement(4412878..4413612) 1 NC_009525.1 hypothetical protein 4413612 5212394 MRA_3955 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285306.1 4412878 R 419947 CDS YP_001285307.1 148663784 5212395 complement(4413902..4414936) 1 NC_009525.1 chromosome partitioning protein ParB 4414936 parB 5212395 parB Mycobacterium tuberculosis H37Ra chromosome partitioning protein ParB YP_001285307.1 4413902 R 419947 CDS YP_001285308.1 148663785 5212396 complement(4414933..4415976) 1 NC_009525.1 chromosome partitioning protein ParA 4415976 parA 5212396 parA Mycobacterium tuberculosis H37Ra chromosome partitioning protein ParA YP_001285308.1 4414933 R 419947 CDS YP_001285309.1 148663786 5212397 complement(4415973..4416647) 1 NC_009525.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4416647 gidB 5212397 gidB Mycobacterium tuberculosis H37Ra 16S rRNA methyltransferase GidB YP_001285309.1 4415973 R 419947 CDS YP_001285310.1 148663787 5212398 complement(4416779..4417342) 1 NC_009525.1 Jag protein 4417342 5212398 MRA_3959 Mycobacterium tuberculosis H37Ra Jag protein YP_001285310.1 4416779 R 419947 CDS YP_001285311.1 148663788 5212399 complement(4417414..4418514) 1 NC_009525.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4418514 5212399 MRA_3960 Mycobacterium tuberculosis H37Ra inner membrane protein translocase component YidC YP_001285311.1 4417414 R 419947 CDS YP_001285312.1 148663789 5212400 complement(4418498..4418860) 1 NC_009525.1 hypothetical protein 4418860 5212400 MRA_3961 Mycobacterium tuberculosis H37Ra hypothetical protein YP_001285312.1 4418498 R 419947 CDS YP_001285313.1 148663790 5212401 complement(4418857..4419234) 1 NC_009525.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4419234 rnpA 5212401 rnpA Mycobacterium tuberculosis H37Ra ribonuclease P YP_001285313.1 4418857 R 419947 CDS YP_001285314.1 148663791 5212779 complement(4419231..4419374) 1 NC_009525.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4419374 rpmH 5212779 rpmH Mycobacterium tuberculosis H37Ra 50S ribosomal protein L34 YP_001285314.1 4419231 R 419947 CDS