-- dump date   	20250217_001036
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
83332000001	part of toxin-antitoxin (TA) operon with Rv0277c
83332000002	mcr19, fragment of putative small regulatory RNA (See DiChiara et al., 2010), cloned from M. bovis BCG~Pasteur; ends not mapped, 66-82 nt band detected by Northern blot in M. bovis BCG Pasteur.
83332000003	similar to insertion sequence element IS986/IS6110 transposase; Putative transposase for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990).
83332000004	mycolyl transferase pseudogene
83332000005	mpr5, fragment of putative small regulatory RNA (See DiChiara et al., 2010), ends not mapped, 100 nt band detected by Northern blot.
83332000006	Possible fragment of transposase (pseudogene). Identical to C-terminal part of S21394 transposase of putative Mycobacterium tuberculosis is element. The transposase described here may be made by a -1 frame shifting mechanism during translation that fuses Rv1149|MTCI65.16 and Rv1150|MTCI65.17. No evidence found to account for discrepancy with previously published sequence. Second copy is Rv1041c|MTCY10G2.08.
83332000007	ncrMT1234, fragment of putative small regulatory RNA (See Pelly et al., 2012), cloned from M. tuberculosis CDC1551; supported by RNA-seq in H37Rv (unpublished data).; Fragment of putative small regulatory RNA
83332000008	mpr6, fragment of putative small regulatory RNA (See DiChiara et al., 2010), ends not mapped, ~118 nt band detected by Northern blot in M. bovis BCG Pasteur.
83332000009	similar to insertion sequence element IS986/IS6110 transposase; Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990)
83332000010	Hypothetical unknown protein (pseudogene), Note that a deletion of DNA (RvD1 region) in Mycobacterium tuberculosis strain H37Rv resulted in a truncated CDS comparatively to Mycobacterium bovis or Mycobacterium tuberculosis strain CDC1551 genomes (see citations below).
83332000011	Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of ala-, gly-rich proteins
83332000012	Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of ala-, gly-rich proteins
83332000013	mcr5, fragment of putative small regulatory RNA (See DiChiara et al., 2010), cloned from M. bovis BCG Pasteur; ends not mapped, ~82 nt band detected by Northern blot.; Fragment of putative small regulatory RNA
83332000014	similar to insertion sequence element IS986/IS6110 transposase; Probable IS6110 transposase. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990)
83332000015	similar to insertion sequence element IS986/IS6110 transposase; Probable IS6110 transposase. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990).
83332000016	Rv2427A, Pseudogene oxyR', inactivated by multiple mutations; identical to sequence in u16243 (see Deretic et al., 1995).
83332000017	similar to insertion sequence element IS986/IS6110 transposase; Probable transposase for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990).
83332000018	mpr11, fragment of putative small regulatory RNA (See DiChiara et al., 2010), ends not mapped, 82-100 nt band detected by Northern blot in M. bovis BCG Pasteur.; Fragment of putative small regulatory RNA
83332000019	mpr12, fragment of putative small regulatory RNA (See DiChiara et al., 2010), ends not mapped, ~118 nt band detected by Northern blot in M. bovis BCG Pasteur.; Fragment of putative small regulatory RNA
83332000020	similar to insertion sequence element IS986/IS6110 transposase; Probable transposase for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990).
83332000021	similar to insertion sequence element IS6110 transposase(fragment); Putative Transposase for IS6110 (fragment). Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007 PMID:17545187).
83332000022	PPE47, Member of Mycobacterium tuberculosis PPE family. Should be continuation of upstream ORF MTV012.36c but is frameshifted due to missing base at 36448 in v012. Sequence has been checked but no error apparent.
83332000023	PPE48, Member of M. tuberculosis PPE family with frameshift due to missing bp in codon 82. The ORF continues in downstream MTV012.35c. The sequence has been checked and no errors were detected.
83332000024	This ORF corresponds to a fusion of MTCY164.38 and MTCY164.39c. Has in-frame amber stop codon
83332000025	similar to insertion sequence element IS986/IS6110 transposase; Probable IS6110 transposase. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (+ 16 aa). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007 PMID:17545187).
83332000026	acetyltransferase (2.3.1.-), contains GNAT domain (GCN5-like N-acetyltransferase. See Vetting et al. 2005), probably pseudogene as appears frameshifted due to 1bp insertion at position 3593438. Frameshift present in all sequenced tubercle bacilli. Start changed since first submission, extended by 50aa.
83332000027	Probable pseudogene moaB3,fragment of pterin-4-alpha-carbinolamine dehydratase,equivalent to C-terminus of MT3426|Q8VJ32 pterin-4-alpha-carbinolamine dehydratase from Mycobacterium tuberculosis strain CDC1551
83332000028	similar to insertion sequence element IS986/IS6110 transposase; Probable transposase for insertion element IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation,the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990).
83332000029	similar to insertion sequence element IS986/IS6110 transposase; Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990).
83332000030	similar to insertion sequence element IS986/IS6110 transposase; Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation, the sequence UUUUAAAG maybe responsible for such a frameshifting event (see McAdam et al., 1990).
83332000031	mpr17, fragment of putative small regulatory RNA (See DiChiara et al., 2010), ends not mapped, 82-118 nt bands detected by Northern blot in M. bovis BCG Pasteur.; Fragment of putative small regulatory RNA
83332000032	mpr18, fragment of putative small regulatory RNA (See DiChiara et al., 2010), ends not mapped, 82 and 100 nt bands detected by Northern blot in M. bovis BCG Pasteur.; Fragment of putative small regulatory RNA
83332000033	ncrMT3949, fragment of putative small regulatory RNA (See Pelly et al., 2012), cloned from M. tuberculosis CDC1551; supported by RNA-seq in H37Rv (unpublished data).; Fragment of putative small regulatory RNA