-- dump date 20140619_154917 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 478434000001 SEQ_END SEQ_END NC_012943.1 4398250 4398250 DR NC_012943.1; contig end 4398250..4398250 Mycobacterium tuberculosis KZN 1435 YP_003029917.1 CDS dnaA NC_012943.1 103 1626 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 103..1626 Mycobacterium tuberculosis KZN 1435 8161237 YP_003029918.1 CDS TBMG_00002 NC_012943.1 2154 3362 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2154..3362 Mycobacterium tuberculosis KZN 1435 8163707 YP_003029919.1 CDS recF NC_012943.1 3382 4539 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3382..4539 Mycobacterium tuberculosis KZN 1435 8163708 YP_003029920.1 CDS TBMG_00004 NC_012943.1 4536 5099 D hypothetical protein 4536..5099 Mycobacterium tuberculosis KZN 1435 8163709 YP_003029921.1 CDS gyrB NC_012943.1 5225 7369 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 5225..7369 Mycobacterium tuberculosis KZN 1435 8163710 YP_003029922.1 CDS TBMG_00006 NC_012943.1 7404 9920 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 7404..9920 Mycobacterium tuberculosis KZN 1435 8163711 YP_003029923.1 CDS TBMG_00007 NC_012943.1 10016 10930 D hypothetical protein 10016..10930 Mycobacterium tuberculosis KZN 1435 8163712 YP_003029924.1 CDS TBMG_00008 NC_012943.1 11976 12413 R hypothetical protein complement(11976..12413) Mycobacterium tuberculosis KZN 1435 8163715 YP_003029925.1 CDS TBMG_00009 NC_012943.1 12570 13118 D iron-regulated peptidyl-prolyl-cis-trans-isomerase A ppiA 12570..13118 Mycobacterium tuberculosis KZN 1435 8163716 YP_003029926.1 CDS TBMG_00010 NC_012943.1 13235 13660 R hypothetical protein complement(13235..13660) Mycobacterium tuberculosis KZN 1435 8163717 YP_003029927.1 CDS TBMG_00011 NC_012943.1 13816 14097 R integral membrane protein involved in inhibition of the Z-ring formation; septation inhibitor protein complement(13816..14097) Mycobacterium tuberculosis KZN 1435 8163718 YP_003029928.1 CDS TBMG_00012 NC_012943.1 14191 14979 D hypothetical protein 14191..14979 Mycobacterium tuberculosis KZN 1435 8163719 YP_003029929.1 CDS TBMG_00013 NC_012943.1 15016 15714 D aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 15016..15714 Mycobacterium tuberculosis KZN 1435 8163720 YP_003029930.1 CDS TBMG_00014 NC_012943.1 15692 17572 R Ser/Thr protein kinase complement(15692..17572) Mycobacterium tuberculosis KZN 1435 8163721 YP_003029931.1 CDS TBMG_00015 NC_012943.1 17569 18846 R Ser/Thr protein kinase complement(17569..18846) Mycobacterium tuberculosis KZN 1435 8163722 YP_003029932.1 CDS TBMG_00016 NC_012943.1 18861 20336 R penicillin-binding protein pbpA complement(18861..20336) Mycobacterium tuberculosis KZN 1435 8163723 YP_003029933.1 CDS TBMG_00017 NC_012943.1 20333 21742 R cell division protein rodA complement(20333..21742) Mycobacterium tuberculosis KZN 1435 8163724 YP_003029934.1 CDS TBMG_00018 NC_012943.1 21739 23283 R serine/threonine phosphatase ppp complement(21739..23283) Mycobacterium tuberculosis KZN 1435 8163725 YP_003029935.1 CDS TBMG_00019 NC_012943.1 23372 23839 R hypothetical protein complement(23372..23839) Mycobacterium tuberculosis KZN 1435 8163726 YP_003029936.1 CDS TBMG_00020 NC_012943.1 23963 25546 R hypothetical protein complement(23963..25546) Mycobacterium tuberculosis KZN 1435 8163727 YP_003029937.1 CDS TBMG_00021 NC_012943.1 26015 26980 R hypothetical protein complement(26015..26980) Mycobacterium tuberculosis KZN 1435 8163729 YP_003029938.1 CDS TBMG_00022 NC_012943.1 27125 27544 R transcriptional regulator whib-like whiB5 complement(27125..27544) Mycobacterium tuberculosis KZN 1435 8163730 YP_003029939.1 CDS TBMG_00023 NC_012943.1 27697 28467 D transcriptional regulator 27697..28467 Mycobacterium tuberculosis KZN 1435 8163731 YP_003029940.1 CDS TBMG_00024 NC_012943.1 28464 29309 D hypothetical protein 28464..29309 Mycobacterium tuberculosis KZN 1435 8163732 YP_003029941.1 CDS TBMG_00025 NC_012943.1 29347 29709 D hypothetical protein 29347..29709 Mycobacterium tuberculosis KZN 1435 8163733 YP_003029942.1 CDS TBMG_00026 NC_012943.1 29824 31170 D hypothetical protein 29824..31170 Mycobacterium tuberculosis KZN 1435 8163734 YP_003029943.1 CDS TBMG_00027 NC_012943.1 31291 31608 D hypothetical protein 31291..31608 Mycobacterium tuberculosis KZN 1435 8163735 YP_003029944.1 CDS TBMG_00028 NC_012943.1 31616 31921 D hypothetical protein 31616..31921 Mycobacterium tuberculosis KZN 1435 8163736 YP_003029945.1 CDS TBMG_03973 NC_012943.1 31926 32069 R hypothetical protein complement(31926..32069) Mycobacterium tuberculosis KZN 1435 8163737 YP_003029946.1 CDS TBMG_00029 NC_012943.1 32159 33256 D hypothetical protein 32159..33256 Mycobacterium tuberculosis KZN 1435 8163738 YP_003029947.1 CDS TBMG_00030 NC_012943.1 33326 33901 D transposase 33326..33901 Mycobacterium tuberculosis KZN 1435 8163739 YP_003029948.1 CDS TBMG_00031 NC_012943.1 34409 36643 D 8-amino-7-oxononanoate synthase 34409..36643 Mycobacterium tuberculosis KZN 1435 8163740 YP_003029949.1 CDS TBMG_00032 NC_012943.1 36710 36973 D acyl carrier protein 36710..36973 Mycobacterium tuberculosis KZN 1435 8163741 YP_003029950.1 CDS TBMG_00033 NC_012943.1 36970 37365 D hypothetical protein 36970..37365 Mycobacterium tuberculosis KZN 1435 8163742 YP_003029951.1 CDS TBMG_00034 NC_012943.1 37362 39050 D fatty-acid-CoA ligase fadD34 37362..39050 Mycobacterium tuberculosis KZN 1435 8163743 YP_003029952.1 CDS TBMG_00035 NC_012943.1 39159 39932 R hypothetical protein complement(39159..39932) Mycobacterium tuberculosis KZN 1435 8163744 YP_003029953.1 CDS TBMG_00036 NC_012943.1 39980 41305 R hypothetical protein complement(39980..41305) Mycobacterium tuberculosis KZN 1435 8163745 YP_003029954.1 CDS TBMG_00037 NC_012943.1 41407 42015 D hypothetical protein 41407..42015 Mycobacterium tuberculosis KZN 1435 8163746 YP_003029955.1 CDS TBMG_00038 NC_012943.1 42107 42454 R hypothetical protein complement(42107..42454) Mycobacterium tuberculosis KZN 1435 8163747 YP_003029956.1 CDS TBMG_00039 NC_012943.1 42536 43468 R hypothetical protein complement(42536..43468) Mycobacterium tuberculosis KZN 1435 8163748 YP_003029957.1 CDS leuS NC_012943.1 43665 46574 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 43665..46574 Mycobacterium tuberculosis KZN 1435 8163749 YP_003029958.1 CDS TBMG_00041 NC_012943.1 46684 47310 R transcriptional regulator, marR-family complement(46684..47310) Mycobacterium tuberculosis KZN 1435 8163750 YP_003029959.1 CDS TBMG_00042 NC_012943.1 47469 48203 R GntR family transcriptional regulator complement(47469..48203) Mycobacterium tuberculosis KZN 1435 8163751 YP_003029960.1 CDS TBMG_00043 NC_012943.1 48336 49130 R oxidoreductase complement(48336..49130) Mycobacterium tuberculosis KZN 1435 8163752 YP_003029961.1 CDS TBMG_00044 NC_012943.1 49146 50042 R hydrolase complement(49146..50042) Mycobacterium tuberculosis KZN 1435 8163753 YP_003029962.1 CDS TBMG_00045 NC_012943.1 50124 51227 R myo-inositol-1-phosphate synthase ino1 complement(50124..51227) Mycobacterium tuberculosis KZN 1435 8163754 YP_003029963.1 CDS TBMG_00046 NC_012943.1 51288 51830 R hypothetical protein complement(51288..51830) Mycobacterium tuberculosis KZN 1435 8163755 YP_003029964.1 CDS TBMG_00047 NC_012943.1 51931 52800 R hypothetical protein complement(51931..52800) Mycobacterium tuberculosis KZN 1435 8163756 YP_003029965.1 CDS TBMG_00048 NC_012943.1 52913 53347 D hypothetical protein 52913..53347 Mycobacterium tuberculosis KZN 1435 8163757 YP_003029966.1 CDS TBMG_00049 NC_012943.1 53340 55802 D bifunctional penicillin-binding protein ponA1 53340..55802 Mycobacterium tuberculosis KZN 1435 8163758 YP_003029967.1 CDS TBMG_00050 NC_012943.1 55799 57481 D hypothetical protein 55799..57481 Mycobacterium tuberculosis KZN 1435 8163759 YP_003029968.1 CDS TBMG_00051 NC_012943.1 57438 58076 D hypothetical protein 57438..58076 Mycobacterium tuberculosis KZN 1435 8163760 YP_003029969.1 CDS rpsF NC_012943.1 58295 58585 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 58295..58585 Mycobacterium tuberculosis KZN 1435 8163761 YP_003029970.1 CDS TBMG_00053 NC_012943.1 58689 59183 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 58689..59183 Mycobacterium tuberculosis KZN 1435 8163762 YP_003029971.1 CDS rpsR NC_012943.1 59225 59479 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 59225..59479 Mycobacterium tuberculosis KZN 1435 8163763 YP_003029972.1 CDS rplI NC_012943.1 59512 59970 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 59512..59970 Mycobacterium tuberculosis KZN 1435 8163764 YP_003029973.1 CDS TBMG_00056 NC_012943.1 59999 60520 D hypothetical protein 59999..60520 Mycobacterium tuberculosis KZN 1435 8163765 YP_003029974.1 CDS TBMG_00057 NC_012943.1 60499 63123 D unwinds double stranded DNA; these Mycobacterial enzymes appear to contain inteins; replicative DNA helicase 60499..63123 Mycobacterium tuberculosis KZN 1435 8163766 YP_003029975.1 CDS TBMG_00058 NC_012943.1 63303 63995 D hypothetical protein 63303..63995 Mycobacterium tuberculosis KZN 1435 8163767 YP_003029976.1 CDS TBMG_00059 NC_012943.1 64012 65070 D hypothetical protein 64012..65070 Mycobacterium tuberculosis KZN 1435 8163768 YP_003029977.1 CDS TBMG_00060 NC_012943.1 65115 65495 R hypothetical protein complement(65115..65495) Mycobacterium tuberculosis KZN 1435 8163769 YP_003029978.1 CDS TBMG_00061 NC_012943.1 65655 66797 D cellulase celA1 65655..66797 Mycobacterium tuberculosis KZN 1435 8163770 YP_003029979.1 CDS TBMG_00062 NC_012943.1 67026 68465 D oxidoreductase 67026..68465 Mycobacterium tuberculosis KZN 1435 8163771 YP_003029980.1 CDS TBMG_03974 NC_012943.1 68521 68682 D hypothetical protein 68521..68682 Mycobacterium tuberculosis KZN 1435 8163772 YP_003029981.1 CDS TBMG_00063 NC_012943.1 68723 71662 D hypothetical protein 68723..71662 Mycobacterium tuberculosis KZN 1435 8163773 YP_003029982.1 CDS TBMG_00064 NC_012943.1 71729 71968 D antitoxin 71729..71968 Mycobacterium tuberculosis KZN 1435 8163774 YP_003029983.1 CDS TBMG_00065 NC_012943.1 71961 72362 D toxin 71961..72362 Mycobacterium tuberculosis KZN 1435 8163775 YP_003029984.1 CDS TBMG_00066 NC_012943.1 72414 74651 R isocitrate dehydrogenase [NADP] icd2 complement(72414..74651) Mycobacterium tuberculosis KZN 1435 8163776 YP_003029985.1 CDS TBMG_00067 NC_012943.1 74769 75338 R TetR family transcriptional regulator complement(74769..75338) Mycobacterium tuberculosis KZN 1435 8163777 YP_003029986.1 CDS TBMG_00068 NC_012943.1 75441 76352 D short chain dehydrogenase 75441..76352 Mycobacterium tuberculosis KZN 1435 8163778 YP_003029987.1 CDS TBMG_00069 NC_012943.1 76377 77762 R L-serine dehydratase sdaA complement(76377..77762) Mycobacterium tuberculosis KZN 1435 8163779 YP_003029988.1 CDS glyA NC_012943.1 77759 79036 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(77759..79036) Mycobacterium tuberculosis KZN 1435 8163780 YP_003029989.1 CDS TBMG_00071 NC_012943.1 79626 80324 D maturase 79626..80324 Mycobacterium tuberculosis KZN 1435 8163781 YP_003029990.1 CDS TBMG_00072 NC_012943.1 80755 81804 D hypothetical protein 80755..81804 Mycobacterium tuberculosis KZN 1435 8163782 YP_003029991.1 CDS TBMG_00073 NC_012943.1 81807 82799 D glutamine-transport ATP-binding protein ABC transporter 81807..82799 Mycobacterium tuberculosis KZN 1435 8163783 YP_003029992.1 CDS TBMG_00074 NC_012943.1 82879 84114 D hypothetical protein 82879..84114 Mycobacterium tuberculosis KZN 1435 8163784 YP_003029993.1 CDS TBMG_00075 NC_012943.1 84127 85299 D aminotransferase 84127..85299 Mycobacterium tuberculosis KZN 1435 8163785 YP_003029994.1 CDS TBMG_00076 NC_012943.1 85314 85703 R hypothetical protein complement(85314..85703) Mycobacterium tuberculosis KZN 1435 8163786 YP_003029995.1 CDS TBMG_00077 NC_012943.1 85767 86621 R oxidoreductase complement(85767..86621) Mycobacterium tuberculosis KZN 1435 8163787 YP_003029996.1 CDS TBMG_00078 NC_012943.1 86659 87264 D transcriptional regulator 86659..87264 Mycobacterium tuberculosis KZN 1435 8162985 YP_003029997.1 CDS TBMG_00079 NC_012943.1 87339 87932 R hypothetical protein complement(87339..87932) Mycobacterium tuberculosis KZN 1435 8162986 YP_003029998.1 CDS TBMG_00080 NC_012943.1 88335 89156 D hypothetical protein 88335..89156 Mycobacterium tuberculosis KZN 1435 8162987 YP_003029999.1 CDS TBMG_00081 NC_012943.1 89153 89611 D hypothetical protein 89153..89611 Mycobacterium tuberculosis KZN 1435 8162988 YP_003030000.1 CDS TBMG_00082 NC_012943.1 89706 90050 D transcriptional regulator 89706..90050 Mycobacterium tuberculosis KZN 1435 8162989 YP_003030001.1 CDS TBMG_00083 NC_012943.1 90055 90534 D oxidoreductase 90055..90534 Mycobacterium tuberculosis KZN 1435 8162990 YP_003030002.1 CDS TBMG_00084 NC_012943.1 90531 92453 D oxidoreductase 90531..92453 Mycobacterium tuberculosis KZN 1435 8162991 YP_003030003.1 CDS TBMG_00085 NC_012943.1 92459 93409 D formate hydrogenlyase hycD 92459..93409 Mycobacterium tuberculosis KZN 1435 8162992 YP_003030004.1 CDS TBMG_00086 NC_012943.1 93420 94082 D hydrogenase hycP 93420..94082 Mycobacterium tuberculosis KZN 1435 8162993 YP_003030005.1 CDS TBMG_00087 NC_012943.1 94082 95548 D hydrogenase hycQ 94082..95548 Mycobacterium tuberculosis KZN 1435 8162994 YP_003030006.1 CDS TBMG_00088 NC_012943.1 95545 97023 D formate hydrogenase hycE 95545..97023 Mycobacterium tuberculosis KZN 1435 8162995 YP_003030007.1 CDS TBMG_00089 NC_012943.1 97058 97732 D hypothetical protein 97058..97732 Mycobacterium tuberculosis KZN 1435 8162996 YP_003030008.1 CDS TBMG_00090 NC_012943.1 97889 98482 D methyltransferase/methylase 97889..98482 Mycobacterium tuberculosis KZN 1435 8162997 YP_003030009.1 CDS TBMG_00091 NC_012943.1 98611 99381 D hypothetical protein 98611..99381 Mycobacterium tuberculosis KZN 1435 8162998 YP_003030010.1 CDS TBMG_00092 NC_012943.1 99815 100582 D bifunctional nucleosidase mtn 99815..100582 Mycobacterium tuberculosis KZN 1435 8162999 YP_003030011.1 CDS TBMG_00093 NC_012943.1 100714 102999 D cation transporter P-type ATPase A ctpA 100714..102999 Mycobacterium tuberculosis KZN 1435 8163000 YP_003030012.1 CDS TBMG_00094 NC_012943.1 102946 103794 R hypothetical protein complement(102946..103794) Mycobacterium tuberculosis KZN 1435 8163001 YP_003030013.1 CDS TBMG_00095 NC_012943.1 103841 104800 R hypothetical protein complement(103841..104800) Mycobacterium tuberculosis KZN 1435 8163002 YP_003030014.1 CDS TBMG_00096 NC_012943.1 104936 105346 R hypothetical protein complement(104936..105346) Mycobacterium tuberculosis KZN 1435 8163003 YP_003030015.1 CDS TBMG_00097 NC_012943.1 105455 106846 D PPE family protein 105455..106846 Mycobacterium tuberculosis KZN 1435 8163004 YP_003030016.1 CDS TBMG_00098 NC_012943.1 106865 107734 D oxidoreductase 106865..107734 Mycobacterium tuberculosis KZN 1435 8163005 YP_003030017.1 CDS TBMG_00099 NC_012943.1 107731 108282 D hypothetical protein 107731..108282 Mycobacterium tuberculosis KZN 1435 8163006 YP_003030018.1 CDS TBMG_00100 NC_012943.1 108287 109909 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 108287..109909 Mycobacterium tuberculosis KZN 1435 8163007 YP_003030019.1 CDS TBMG_00101 NC_012943.1 109914 110150 D hypothetical protein 109914..110150 Mycobacterium tuberculosis KZN 1435 8163008 YP_003030020.1 CDS TBMG_00102 NC_012943.1 110132 117670 D peptide synthetase nrp 110132..117670 Mycobacterium tuberculosis KZN 1435 8163009 YP_003030021.1 CDS TBMG_00103 NC_012943.1 117845 119830 D hypothetical protein 117845..119830 Mycobacterium tuberculosis KZN 1435 8163010 YP_003030022.1 CDS TBMG_00104 NC_012943.1 120046 122304 R cation-transporter P-type ATPase B ctpB complement(120046..122304) Mycobacterium tuberculosis KZN 1435 8163011 YP_003030023.1 CDS TBMG_00105 NC_012943.1 122448 123962 D hypothetical protein 122448..123962 Mycobacterium tuberculosis KZN 1435 8163012 YP_003030024.1 CDS rpmB NC_012943.1 124111 124395 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(124111..124395) Mycobacterium tuberculosis KZN 1435 8163013 YP_003030025.1 CDS TBMG_00107 NC_012943.1 124505 125701 D hypothetical protein 124505..125701 Mycobacterium tuberculosis KZN 1435 8163014 YP_003030026.1 CDS TBMG_00108 NC_012943.1 125796 130673 R cation-transporting ATPase complement(125796..130673) Mycobacterium tuberculosis KZN 1435 8163015 YP_003030027.1 CDS TBMG_00109 NC_012943.1 131027 131260 R hypothetical protein complement(131027..131260) Mycobacterium tuberculosis KZN 1435 8163016 YP_003030028.1 CDS TBMG_00110 NC_012943.1 131404 133005 D PE-PGRS family protein 131404..133005 Mycobacterium tuberculosis KZN 1435 8163017 YP_003030029.1 CDS TBMG_00111 NC_012943.1 133048 133902 D hypothetical protein 133048..133902 Mycobacterium tuberculosis KZN 1435 8163018 YP_003030030.1 CDS TBMG_00112 NC_012943.1 134083 136140 D transmembrane acyltransferase 134083..136140 Mycobacterium tuberculosis KZN 1435 8163019 YP_003030031.1 CDS TBMG_00113 NC_012943.1 136422 137378 D GDP-mannose 4,6-dehydratase gca 136422..137378 Mycobacterium tuberculosis KZN 1435 8163020 YP_003030032.1 CDS TBMG_00114 NC_012943.1 137452 138042 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 137452..138042 Mycobacterium tuberculosis KZN 1435 8163021 YP_003030033.1 CDS TBMG_00115 NC_012943.1 138074 138646 D D-alpha,beta-D-heptose-1,7-biphosphate phosphatase gmhB 138074..138646 Mycobacterium tuberculosis KZN 1435 8163022 YP_003030034.1 CDS TBMG_00116 NC_012943.1 138646 139806 D D-alpha-D-heptose-7-phosphate kinase hddA 138646..139806 Mycobacterium tuberculosis KZN 1435 8163023 YP_003030035.1 CDS TBMG_00117 NC_012943.1 140400 141155 R hypothetical protein complement(140400..141155) Mycobacterium tuberculosis KZN 1435 8163024 YP_003030036.1 CDS TBMG_00118 NC_012943.1 141327 142277 D oxidative stress response regulatory protein oxyS 141327..142277 Mycobacterium tuberculosis KZN 1435 8163025 YP_003030037.1 CDS TBMG_00119 NC_012943.1 142261 144018 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(142261..144018) Mycobacterium tuberculosis KZN 1435 8163026 YP_003030038.1 CDS TBMG_00120 NC_012943.1 144131 145759 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 144131..145759 Mycobacterium tuberculosis KZN 1435 8163027 YP_003030039.1 CDS TBMG_00121 NC_012943.1 145760 147904 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(145760..147904) Mycobacterium tuberculosis KZN 1435 8163028 YP_003030040.1 CDS TBMG_00122 NC_012943.1 148041 148475 R F420-dependent enzyme complement(148041..148475) Mycobacterium tuberculosis KZN 1435 8163029 YP_003030041.1 CDS TBMG_00123 NC_012943.1 148624 148992 D hypothetical protein 148624..148992 Mycobacterium tuberculosis KZN 1435 8163030 YP_003030042.1 CDS TBMG_00124 NC_012943.1 148989 149357 D hypothetical protein 148989..149357 Mycobacterium tuberculosis KZN 1435 8163031 YP_003030043.1 CDS TBMG_03975 NC_012943.1 149624 150769 D PE-PGRS family protein 149624..150769 Mycobacterium tuberculosis KZN 1435 8163032 YP_003030044.1 CDS TBMG_03976 NC_012943.1 150714 151310 D PE-PGRS family protein 150714..151310 Mycobacterium tuberculosis KZN 1435 8163033 YP_003030045.1 CDS TBMG_00126 NC_012943.1 151501 152529 D serine protease pepA 151501..152529 Mycobacterium tuberculosis KZN 1435 8163034 YP_003030046.1 CDS TBMG_00127 NC_012943.1 152638 154443 D trehalose synthase treS 152638..154443 Mycobacterium tuberculosis KZN 1435 8163035 YP_003030047.1 CDS TBMG_00128 NC_012943.1 154493 155860 D hypothetical protein 154493..155860 Mycobacterium tuberculosis KZN 1435 8163036 YP_003030048.1 CDS TBMG_00129 NC_012943.1 155928 156707 D hypothetical protein 155928..156707 Mycobacterium tuberculosis KZN 1435 8163037 YP_003030049.1 CDS TBMG_00130 NC_012943.1 156839 157861 R secreted fibronectin-binding protein C antigen 85-C fbpC complement(156839..157861) Mycobacterium tuberculosis KZN 1435 8163038 YP_003030050.1 CDS TBMG_00131 NC_012943.1 158108 158563 D hypothetical protein 158108..158563 Mycobacterium tuberculosis KZN 1435 8163039 YP_003030051.1 CDS TBMG_00132 NC_012943.1 158576 159919 R acyl-CoA dehydrogenase complement(158576..159919) Mycobacterium tuberculosis KZN 1435 8163040 YP_003030052.1 CDS TBMG_00133 NC_012943.1 159961 161043 R F420-dependent glucose-6-phosphate dehydrogenase complement(159961..161043) Mycobacterium tuberculosis KZN 1435 8163041 YP_003030053.1 CDS TBMG_00134 NC_012943.1 161130 161735 D acetyltransferase 161130..161735 Mycobacterium tuberculosis KZN 1435 8163042 YP_003030054.1 CDS TBMG_00135 NC_012943.1 162032 162934 D epoxide hydrolase ephF 162032..162934 Mycobacterium tuberculosis KZN 1435 8163043 YP_003030055.1 CDS TBMG_00136 NC_012943.1 162905 163510 R transcriptional regulator complement(162905..163510) Mycobacterium tuberculosis KZN 1435 8163044 YP_003030056.1 CDS TBMG_00137 NC_012943.1 163627 164952 D cytochrome P450 138 cyp138 163627..164952 Mycobacterium tuberculosis KZN 1435 8163045 YP_003030057.1 CDS TBMG_00138 NC_012943.1 164973 165521 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(164973..165521) Mycobacterium tuberculosis KZN 1435 8163046 YP_003030058.1 CDS TBMG_00139 NC_012943.1 165584 166087 D hypothetical protein 165584..166087 Mycobacterium tuberculosis KZN 1435 8163047 YP_003030059.1 CDS TBMG_00140 NC_012943.1 166088 167110 D oxidoreductase 166088..167110 Mycobacterium tuberculosis KZN 1435 8163048 YP_003030060.1 CDS TBMG_00141 NC_012943.1 167171 167551 D hypothetical protein 167171..167551 Mycobacterium tuberculosis KZN 1435 8163049 YP_003030061.1 CDS TBMG_00142 NC_012943.1 167532 167942 R hypothetical protein complement(167532..167942) Mycobacterium tuberculosis KZN 1435 8163050 YP_003030062.1 CDS TBMG_00143 NC_012943.1 167972 168898 D hypothetical protein 167972..168898 Mycobacterium tuberculosis KZN 1435 8163051 YP_003030063.1 CDS TBMG_00144 NC_012943.1 168965 170443 R hypothetical protein complement(168965..170443) Mycobacterium tuberculosis KZN 1435 8163052 YP_003030064.1 CDS TBMG_00145 NC_012943.1 170545 171387 D TetR family transcriptional regulator 170545..171387 Mycobacterium tuberculosis KZN 1435 8163053 YP_003030065.1 CDS TBMG_00146 NC_012943.1 171476 171733 D hypothetical protein 171476..171733 Mycobacterium tuberculosis KZN 1435 8163054 YP_003030066.1 CDS TBMG_03977 NC_012943.1 171742 172107 D hypothetical protein 171742..172107 Mycobacterium tuberculosis KZN 1435 8163055 YP_003030067.1 CDS TBMG_00147 NC_012943.1 172141 173082 D hypothetical protein 172141..173082 Mycobacterium tuberculosis KZN 1435 8163056 YP_003030068.1 CDS TBMG_00148 NC_012943.1 173177 174697 D aldehyde dehydrogenase 173177..174697 Mycobacterium tuberculosis KZN 1435 8163057 YP_003030069.1 CDS TBMG_00149 NC_012943.1 174772 175632 D short-chain type dehydrogenase/reductase 174772..175632 Mycobacterium tuberculosis KZN 1435 8163058 YP_003030070.1 CDS TBMG_00150 NC_012943.1 175639 176607 D quinone oxidoreductase 175639..176607 Mycobacterium tuberculosis KZN 1435 8163059 YP_003030071.1 CDS TBMG_00151 NC_012943.1 176604 176891 R hypothetical protein complement(176604..176891) Mycobacterium tuberculosis KZN 1435 8163060 YP_003030072.1 CDS TBMG_00152 NC_012943.1 177482 179248 R PE family protein complement(177482..179248) Mycobacterium tuberculosis KZN 1435 8163061 YP_003030073.1 CDS TBMG_00153 NC_012943.1 179258 180859 R PE family protein complement(179258..180859) Mycobacterium tuberculosis KZN 1435 8163062 YP_003030074.1 CDS TBMG_00154 NC_012943.1 181094 181924 R phosphotyrosine protein phosphatase ptpb complement(181094..181924) Mycobacterium tuberculosis KZN 1435 8163063 YP_003030075.1 CDS TBMG_00155 NC_012943.1 181926 183149 R acyl-CoA dehydrogenase complement(181926..183149) Mycobacterium tuberculosis KZN 1435 8163788 YP_003030076.1 CDS TBMG_03978 NC_012943.1 183354 183500 D response regulator receiver domain-containing protein 183354..183500 Mycobacterium tuberculosis KZN 1435 8163789 YP_003030077.1 CDS TBMG_00156 NC_012943.1 183561 184661 D NAD(P) transhydrogenase alpha subunit pntAa 183561..184661 Mycobacterium tuberculosis KZN 1435 8163790 YP_003030078.1 CDS TBMG_00157 NC_012943.1 184662 184994 D NAD(P) transhydrogenase alpha subunit pntAb 184662..184994 Mycobacterium tuberculosis KZN 1435 8163791 YP_003030079.1 CDS TBMG_00158 NC_012943.1 184991 186418 D NAD(P) transhydrogenase beta subunit pntB 184991..186418 Mycobacterium tuberculosis KZN 1435 8163792 YP_003030080.1 CDS TBMG_03979 NC_012943.1 186434 186559 R hypothetical protein complement(186434..186559) Mycobacterium tuberculosis KZN 1435 8163793 YP_003030081.1 CDS TBMG_00159 NC_012943.1 186724 187368 D TetR family transcriptional regulator 186724..187368 Mycobacterium tuberculosis KZN 1435 8163794 YP_003030082.1 CDS TBMG_00160 NC_012943.1 187372 188778 R PE family protein complement(187372..188778) Mycobacterium tuberculosis KZN 1435 8161809 YP_003030083.1 CDS TBMG_00161 NC_012943.1 188870 190378 R PE family protein complement(188870..190378) Mycobacterium tuberculosis KZN 1435 8161810 YP_003030084.1 CDS TBMG_00162 NC_012943.1 190546 191895 D oxidoreductase 190546..191895 Mycobacterium tuberculosis KZN 1435 8161811 YP_003030085.1 CDS TBMG_00163 NC_012943.1 191923 193074 R zinc-type alcohol dehydrogenase E subunit adhE complement(191923..193074) Mycobacterium tuberculosis KZN 1435 8161812 YP_003030086.1 CDS TBMG_00164 NC_012943.1 193056 193511 D hypothetical protein 193056..193511 Mycobacterium tuberculosis KZN 1435 8161814 YP_003030087.1 CDS TBMG_00165 NC_012943.1 193565 194050 D hypothetical protein 193565..194050 Mycobacterium tuberculosis KZN 1435 8161813 YP_003030088.1 CDS TBMG_00166 NC_012943.1 194083 194877 R GntR family transcriptional regulator complement(194083..194877) Mycobacterium tuberculosis KZN 1435 8161815 YP_003030089.1 CDS TBMG_00167 NC_012943.1 194932 196596 D activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 194932..196596 Mycobacterium tuberculosis KZN 1435 8161816 YP_003030090.1 CDS TBMG_00168 NC_012943.1 196800 197597 D hypothetical protein 196800..197597 Mycobacterium tuberculosis KZN 1435 8161817 YP_003030091.1 CDS TBMG_00169 NC_012943.1 197599 198468 D hypothetical protein 197599..198468 Mycobacterium tuberculosis KZN 1435 8161818 YP_003030092.1 CDS TBMG_00170 NC_012943.1 198473 199837 D MCE-family protein mce1A 198473..199837 Mycobacterium tuberculosis KZN 1435 8161819 YP_003030093.1 CDS TBMG_00171 NC_012943.1 199834 200874 D MCE-family protein mce1B 199834..200874 Mycobacterium tuberculosis KZN 1435 8161820 YP_003030094.1 CDS TBMG_00172 NC_012943.1 200913 202418 D MCE-family protein mce1C 200913..202418 Mycobacterium tuberculosis KZN 1435 8161821 YP_003030095.1 CDS TBMG_00173 NC_012943.1 202415 204007 D MCE-family protein mce1D 202415..204007 Mycobacterium tuberculosis KZN 1435 8161822 YP_003030096.1 CDS TBMG_00174 NC_012943.1 204007 205176 D MCE-family lipoprotein mce1E 204007..205176 Mycobacterium tuberculosis KZN 1435 8161823 YP_003030097.1 CDS TBMG_00175 NC_012943.1 205170 206717 D MCE-family protein mce1F 205170..206717 Mycobacterium tuberculosis KZN 1435 8161824 YP_003030098.1 CDS TBMG_00176 NC_012943.1 206753 207394 D hypothetical protein 206753..207394 Mycobacterium tuberculosis KZN 1435 8161825 YP_003030099.1 CDS TBMG_00177 NC_012943.1 207397 208359 D hypothetical protein 207397..208359 Mycobacterium tuberculosis KZN 1435 8161826 YP_003030100.1 CDS TBMG_00178 NC_012943.1 208356 208910 D MCE-associated protein 208356..208910 Mycobacterium tuberculosis KZN 1435 8161827 YP_003030101.1 CDS TBMG_00179 NC_012943.1 208877 209611 D hypothetical protein 208877..209611 Mycobacterium tuberculosis KZN 1435 8161828 YP_003030102.1 CDS TBMG_00180 NC_012943.1 209642 210751 R hypothetical protein complement(209642..210751) Mycobacterium tuberculosis KZN 1435 8161829 YP_003030103.1 CDS TBMG_00181 NC_012943.1 210831 212189 R hypothetical protein complement(210831..212189) Mycobacterium tuberculosis KZN 1435 8161830 YP_003030104.1 CDS TBMG_00182 NC_012943.1 212216 212950 R hypothetical protein complement(212216..212950) Mycobacterium tuberculosis KZN 1435 8161831 YP_003030105.1 CDS TBMG_00183 NC_012943.1 212967 214079 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 complement(212967..214079) Mycobacterium tuberculosis KZN 1435 8161832 YP_003030106.1 CDS TBMG_00184 NC_012943.1 214027 214866 D lysophospholipase 214027..214866 Mycobacterium tuberculosis KZN 1435 8161834 YP_003030107.1 CDS TBMG_00185 NC_012943.1 214908 215657 D hypothetical protein 214908..215657 Mycobacterium tuberculosis KZN 1435 8161833 YP_003030108.1 CDS TBMG_00186 NC_012943.1 215654 216163 D hypothetical protein 215654..216163 Mycobacterium tuberculosis KZN 1435 8161835 YP_003030109.1 CDS TBMG_00187 NC_012943.1 216208 218283 D beta-glucosidase bglS 216208..218283 Mycobacterium tuberculosis KZN 1435 8161836 YP_003030110.1 CDS TBMG_00188 NC_012943.1 218644 219306 D O-methyltransferase 218644..219306 Mycobacterium tuberculosis KZN 1435 8161837 YP_003030111.1 CDS TBMG_00189 NC_012943.1 219425 219856 D hypothetical protein 219425..219856 Mycobacterium tuberculosis KZN 1435 8161838 YP_003030112.1 CDS TBMG_00190 NC_012943.1 219935 221662 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(219935..221662) Mycobacterium tuberculosis KZN 1435 8161839 YP_003030113.1 CDS TBMG_00191 NC_012943.1 221810 222100 D hypothetical protein 221810..222100 Mycobacterium tuberculosis KZN 1435 8161840 YP_003030114.1 CDS TBMG_00192 NC_012943.1 222228 223469 D hypothetical protein 222228..223469 Mycobacterium tuberculosis KZN 1435 8161841 YP_003030115.1 CDS TBMG_00193 NC_012943.1 223503 224603 D hypothetical protein 223503..224603 Mycobacterium tuberculosis KZN 1435 8161842 YP_003030116.1 CDS TBMG_00194 NC_012943.1 224663 226510 R hypothetical protein complement(224663..226510) Mycobacterium tuberculosis KZN 1435 8161843 YP_003030117.1 CDS TBMG_00195 NC_012943.1 226817 230401 D drugs-transport transmembrane ATP-binding protein ABC transporter 226817..230401 Mycobacterium tuberculosis KZN 1435 8161844 YP_003030118.1 CDS TBMG_00196 NC_012943.1 230775 231473 D two component system transcriptional regulator, luxR-family 230775..231473 Mycobacterium tuberculosis KZN 1435 8161845 YP_003030119.1 CDS TBMG_00197 NC_012943.1 231586 232170 D transcriptional regulator 231586..232170 Mycobacterium tuberculosis KZN 1435 8161846 YP_003030120.1 CDS TBMG_00198 NC_012943.1 232167 234416 D oxidoreductase 232167..234416 Mycobacterium tuberculosis KZN 1435 8161847 YP_003030121.1 CDS TBMG_00199 NC_012943.1 234457 236448 R zinc metalloprotease complement(234457..236448) Mycobacterium tuberculosis KZN 1435 8161848 YP_003030122.1 CDS TBMG_00200 NC_012943.1 236491 237150 D hypothetical protein 236491..237150 Mycobacterium tuberculosis KZN 1435 8161849 YP_003030123.1 CDS TBMG_00201 NC_012943.1 237147 237836 D hypothetical protein 237147..237836 Mycobacterium tuberculosis KZN 1435 8161850 YP_003030124.1 CDS TBMG_00202 NC_012943.1 237833 238330 R hypothetical protein complement(237833..238330) Mycobacterium tuberculosis KZN 1435 8161851 YP_003030125.1 CDS TBMG_00203 NC_012943.1 238333 241233 R transmembrane transporter mmpL11 complement(238333..241233) Mycobacterium tuberculosis KZN 1435 8161852 YP_003030126.1 CDS TBMG_00204 NC_012943.1 241455 241865 D hypothetical protein 241455..241865 Mycobacterium tuberculosis KZN 1435 8161853 YP_003030127.1 CDS TBMG_00205 NC_012943.1 241917 243200 R hypothetical protein complement(241917..243200) Mycobacterium tuberculosis KZN 1435 8161854 YP_003030128.1 CDS TBMG_00206 NC_012943.1 243325 244428 D hypothetical protein 243325..244428 Mycobacterium tuberculosis KZN 1435 8161855 YP_003030129.1 CDS TBMG_00207 NC_012943.1 244425 247259 R transmembrane transporter mmpL3 complement(244425..247259) Mycobacterium tuberculosis KZN 1435 8161856 YP_003030130.1 CDS TBMG_00208 NC_012943.1 247325 248059 R hypothetical protein complement(247325..248059) Mycobacterium tuberculosis KZN 1435 8161857 YP_003030131.1 CDS trmB NC_012943.1 248056 248847 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(248056..248847) Mycobacterium tuberculosis KZN 1435 8161858 YP_003030132.1 CDS TBMG_00210 NC_012943.1 248979 250064 D hypothetical protein 248979..250064 Mycobacterium tuberculosis KZN 1435 8161859 YP_003030133.1 CDS TBMG_00211 NC_012943.1 250061 251539 D hypothetical protein 250061..251539 Mycobacterium tuberculosis KZN 1435 8161860 YP_003030134.1 CDS TBMG_00212 NC_012943.1 251723 253543 D catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 251723..253543 Mycobacterium tuberculosis KZN 1435 8161861 YP_003030135.1 CDS TBMG_00213 NC_012943.1 253610 254581 R AsnC family transcriptional regulator complement(253610..254581) Mycobacterium tuberculosis KZN 1435 8161862 YP_003030136.1 CDS TBMG_00214 NC_012943.1 254578 255909 R methyltransferase/methylase complement(254578..255909) Mycobacterium tuberculosis KZN 1435 8161863 YP_003030137.1 CDS TBMG_00215 NC_012943.1 256005 257618 D activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 256005..257618 Mycobacterium tuberculosis KZN 1435 8161864 YP_003030138.1 CDS TBMG_00216 NC_012943.1 257724 258845 R acyl-CoA dehydrogenase complement(257724..258845) Mycobacterium tuberculosis KZN 1435 8161865 YP_003030139.1 CDS TBMG_00217 NC_012943.1 258854 259867 D hypothetical protein 258854..259867 Mycobacterium tuberculosis KZN 1435 8161866 YP_003030140.1 CDS TBMG_00218 NC_012943.1 259864 260772 R esterase lipW complement(259864..260772) Mycobacterium tuberculosis KZN 1435 8161867 YP_003030141.1 CDS TBMG_00219 NC_012943.1 260865 262193 D hypothetical protein 260865..262193 Mycobacterium tuberculosis KZN 1435 8161868 YP_003030142.1 CDS TBMG_00220 NC_012943.1 262195 262743 D hypothetical protein 262195..262743 Mycobacterium tuberculosis KZN 1435 8161869 YP_003030143.1 CDS TBMG_00221 NC_012943.1 262753 263964 D esterase lipC 262753..263964 Mycobacterium tuberculosis KZN 1435 8161870 YP_003030144.1 CDS TBMG_00222 NC_012943.1 264008 265417 D hypothetical protein 264008..265417 Mycobacterium tuberculosis KZN 1435 8161871 YP_003030145.1 CDS TBMG_00223 NC_012943.1 265448 266236 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 265448..266236 Mycobacterium tuberculosis KZN 1435 8161872 YP_003030146.1 CDS TBMG_00224 NC_012943.1 266242 267705 R aldehyde dehydrogenase complement(266242..267705) Mycobacterium tuberculosis KZN 1435 8161873 YP_003030147.1 CDS TBMG_00225 NC_012943.1 267804 268568 R methyltransferase/methylase complement(267804..268568) Mycobacterium tuberculosis KZN 1435 8161874 YP_003030148.1 CDS TBMG_00226 NC_012943.1 268604 269758 D hypothetical protein 268604..269758 Mycobacterium tuberculosis KZN 1435 8161875 YP_003030149.1 CDS TBMG_00227 NC_012943.1 269775 271505 R hypothetical protein complement(269775..271505) Mycobacterium tuberculosis KZN 1435 8161876 YP_003030150.1 CDS TBMG_00228 NC_012943.1 271515 272780 R hypothetical protein complement(271515..272780) Mycobacterium tuberculosis KZN 1435 8161877 YP_003030151.1 CDS TBMG_00229 NC_012943.1 272996 274219 D membrane acyltransferase 272996..274219 Mycobacterium tuberculosis KZN 1435 8161878 YP_003030152.1 CDS TBMG_03980 NC_012943.1 274247 274660 R toxin complement(274247..274660) Mycobacterium tuberculosis KZN 1435 8161879 YP_003030153.1 CDS TBMG_03981 NC_012943.1 274651 274845 R hypothetical protein complement(274651..274845) Mycobacterium tuberculosis KZN 1435 8161880 YP_003030154.1 CDS TBMG_00231 NC_012943.1 274924 275904 R phosphotriesterase php complement(274924..275904) Mycobacterium tuberculosis KZN 1435 8161881 YP_003030155.1 CDS TBMG_00232 NC_012943.1 275999 277705 D acyl-CoA dehydrogenase 275999..277705 Mycobacterium tuberculosis KZN 1435 8161882 YP_003030156.1 CDS TBMG_00233 NC_012943.1 277840 278529 D TetR family transcriptional regulator 277840..278529 Mycobacterium tuberculosis KZN 1435 8161883 YP_003030157.1 CDS TBMG_00234 NC_012943.1 278526 279470 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit beta 278526..279470 Mycobacterium tuberculosis KZN 1435 8161884 YP_003030158.1 CDS gabD1 NC_012943.1 279546 281081 R NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase complement(279546..281081) Mycobacterium tuberculosis KZN 1435 8161885 YP_003030159.1 CDS TBMG_00236 NC_012943.1 281107 282555 R hypothetical protein complement(281107..282555) Mycobacterium tuberculosis KZN 1435 8161886 YP_003030160.1 CDS TBMG_00237 NC_012943.1 282590 286792 R hypothetical protein complement(282590..286792) Mycobacterium tuberculosis KZN 1435 8161887 YP_003030161.1 CDS TBMG_00238 NC_012943.1 286839 287012 R hypothetical protein complement(286839..287012) Mycobacterium tuberculosis KZN 1435 8161888 YP_003030162.1 CDS TBMG_00239 NC_012943.1 287127 288293 D hypothetical protein 287127..288293 Mycobacterium tuberculosis KZN 1435 8162332 YP_003030163.1 CDS TBMG_00240 NC_012943.1 288369 288983 D TetR family transcriptional regulator 288369..288983 Mycobacterium tuberculosis KZN 1435 8162412 YP_003030164.1 CDS TBMG_00241 NC_012943.1 289045 289278 D antitoxin 289045..289278 Mycobacterium tuberculosis KZN 1435 8162413 YP_003030165.1 CDS TBMG_00242 NC_012943.1 289286 289723 D toxin 289286..289723 Mycobacterium tuberculosis KZN 1435 8162414 YP_003030166.1 CDS TBMG_00243 NC_012943.1 289753 290595 R hypothetical protein complement(289753..290595) Mycobacterium tuberculosis KZN 1435 8162415 YP_003030167.1 CDS fabG NC_012943.1 290606 291970 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(290606..291970) Mycobacterium tuberculosis KZN 1435 8162416 YP_003030168.1 CDS TBMG_00245 NC_012943.1 292112 293434 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 292112..293434 Mycobacterium tuberculosis KZN 1435 8162417 YP_003030169.1 CDS TBMG_00246 NC_012943.1 293738 295573 R acyl-CoA dehydrogenase complement(293738..295573) Mycobacterium tuberculosis KZN 1435 8162418 YP_003030170.1 CDS TBMG_00247 NC_012943.1 295945 296433 D oxidoreductase 295945..296433 Mycobacterium tuberculosis KZN 1435 8162419 YP_003030171.1 CDS TBMG_00248 NC_012943.1 296749 298059 D hypothetical protein 296749..298059 Mycobacterium tuberculosis KZN 1435 8162420 YP_003030172.1 CDS TBMG_00249 NC_012943.1 298056 298802 R catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; fumarate reductase iron-sulfur subunit complement(298056..298802) Mycobacterium tuberculosis KZN 1435 8162421 YP_003030173.1 CDS sdhA NC_012943.1 298803 300743 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(298803..300743) Mycobacterium tuberculosis KZN 1435 8162422 YP_003030174.1 CDS TBMG_00251 NC_012943.1 300774 301595 R succinate dehydrogenase membrane anchor subunit complement(300774..301595) Mycobacterium tuberculosis KZN 1435 8162423 YP_003030175.1 CDS TBMG_00252 NC_012943.1 301675 301968 R hypothetical protein complement(301675..301968) Mycobacterium tuberculosis KZN 1435 8162424 YP_003030176.1 CDS TBMG_00253 NC_012943.1 302113 302592 R heat shock protein hsp complement(302113..302592) Mycobacterium tuberculosis KZN 1435 8162425 YP_003030177.1 CDS TBMG_00254 NC_012943.1 302806 305367 D nitrite reductase [NAD(P)H] large subunit nirB 302806..305367 Mycobacterium tuberculosis KZN 1435 8162426 YP_003030178.1 CDS TBMG_00255 NC_012943.1 305393 305749 D nitrite reductase [NAD(P)H] small subunit nirD 305393..305749 Mycobacterium tuberculosis KZN 1435 8162427 YP_003030179.1 CDS TBMG_00256 NC_012943.1 305765 306289 R bifunctional cobalamin biosynthesis protein cobU complement(305765..306289) Mycobacterium tuberculosis KZN 1435 8162428 YP_003030180.1 CDS TBMG_00257 NC_012943.1 306314 307798 R catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase complement(306314..307798) Mycobacterium tuberculosis KZN 1435 8162429 YP_003030181.1 CDS TBMG_00258 NC_012943.1 307817 309487 R PPE family protein complement(307817..309487) Mycobacterium tuberculosis KZN 1435 8162430 YP_003030182.1 CDS TBMG_03982 NC_012943.1 309639 310013 D hypothetical protein 309639..310013 Mycobacterium tuberculosis KZN 1435 8162431 YP_003030183.1 CDS TBMG_00259 NC_012943.1 309877 310209 R hypothetical protein complement(309877..310209) Mycobacterium tuberculosis KZN 1435 8162432 YP_003030184.1 CDS TBMG_00260 NC_012943.1 310234 310689 R hypothetical protein complement(310234..310689) Mycobacterium tuberculosis KZN 1435 8162433 YP_003030185.1 CDS TBMG_00261 NC_012943.1 310714 311457 R hypothetical protein complement(310714..311457) Mycobacterium tuberculosis KZN 1435 8162434 YP_003030186.1 CDS TBMG_00262 NC_012943.1 311454 312599 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; bifunctional uroporphyrinogen-III synthetase/response regulator domain protein complement(311454..312599) Mycobacterium tuberculosis KZN 1435 8162435 YP_003030187.1 CDS TBMG_00263 NC_012943.1 312699 314108 R membrane nitrite extrusion protein narK3 complement(312699..314108) Mycobacterium tuberculosis KZN 1435 8162436 YP_003030188.1 CDS TBMG_00264 NC_012943.1 314249 314794 R aminoglycoside 2-N-acetyltransferase aac complement(314249..314794) Mycobacterium tuberculosis KZN 1435 8162437 YP_003030189.1 CDS TBMG_00265 NC_012943.1 314804 315706 R hypothetical protein complement(314804..315706) Mycobacterium tuberculosis KZN 1435 8162438 YP_003030190.1 CDS TBMG_00266 NC_012943.1 315723 316376 R hypothetical protein complement(315723..316376) Mycobacterium tuberculosis KZN 1435 8162439 YP_003030191.1 CDS TBMG_00267 NC_012943.1 316451 317443 R periplasmic iron-transport lipoprotein complement(316451..317443) Mycobacterium tuberculosis KZN 1435 8162440 YP_003030192.1 CDS TBMG_00268 NC_012943.1 317465 321094 R 5-oxoprolinase complement(317465..321094) Mycobacterium tuberculosis KZN 1435 8162441 YP_003030193.1 CDS TBMG_00269 NC_012943.1 321271 322662 D membrane nitrite extrusion protein narU 321271..322662 Mycobacterium tuberculosis KZN 1435 8162442 YP_003030194.1 CDS TBMG_00270 NC_012943.1 322704 323213 R hypothetical protein complement(322704..323213) Mycobacterium tuberculosis KZN 1435 8162443 YP_003030195.1 CDS TBMG_00271 NC_012943.1 323278 324471 R hypothetical protein complement(323278..324471) Mycobacterium tuberculosis KZN 1435 8162444 YP_003030196.1 CDS TBMG_00272 NC_012943.1 324507 326189 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 324507..326189 Mycobacterium tuberculosis KZN 1435 8162445 YP_003030197.1 CDS TBMG_00273 NC_012943.1 326206 328401 R acyl-CoA dehydrogenase complement(326206..328401) Mycobacterium tuberculosis KZN 1435 8162446 YP_003030198.1 CDS TBMG_00274 NC_012943.1 328515 329648 R hypothetical protein complement(328515..329648) Mycobacterium tuberculosis KZN 1435 8162447 YP_003030199.1 CDS TBMG_00275 NC_012943.1 329645 330265 R transcriptional regulator complement(329645..330265) Mycobacterium tuberculosis KZN 1435 8162448 YP_003030200.1 CDS TBMG_00276 NC_012943.1 330320 330943 D hypothetical protein 330320..330943 Mycobacterium tuberculosis KZN 1435 8162449 YP_003030201.1 CDS TBMG_00277 NC_012943.1 330873 331598 R TetR family transcriptional regulator complement(330873..331598) Mycobacterium tuberculosis KZN 1435 8162450 YP_003030202.1 CDS TBMG_00278 NC_012943.1 331688 332608 D hypothetical protein 331688..332608 Mycobacterium tuberculosis KZN 1435 8162451 YP_003030203.1 CDS TBMG_00279 NC_012943.1 332648 333076 R toxin complement(332648..333076) Mycobacterium tuberculosis KZN 1435 8162452 YP_003030204.1 CDS TBMG_00280 NC_012943.1 333100 333273 R antitoxin complement(333100..333273) Mycobacterium tuberculosis KZN 1435 8162453 YP_003030205.1 CDS TBMG_03983 NC_012943.1 333377 336280 R PE-PGRS family protein complement(333377..336280) Mycobacterium tuberculosis KZN 1435 8162454 YP_003030206.1 CDS TBMG_00283 NC_012943.1 336439 339198 R hypothetical protein complement(336439..339198) Mycobacterium tuberculosis KZN 1435 8162455 YP_003030207.1 CDS TBMG_00284 NC_012943.1 339427 341961 R PE-PGRS family protein complement(339427..341961) Mycobacterium tuberculosis KZN 1435 8162456 YP_003030208.1 CDS TBMG_00285 NC_012943.1 342231 343841 D PPE family protein 342231..343841 Mycobacterium tuberculosis KZN 1435 8162457 YP_003030209.1 CDS TBMG_00286 NC_012943.1 343865 344773 D hypothetical protein 343865..344773 Mycobacterium tuberculosis KZN 1435 8162458 YP_003030210.1 CDS TBMG_00287 NC_012943.1 344997 346892 D hypothetical protein 344997..346892 Mycobacterium tuberculosis KZN 1435 8162459 YP_003030211.1 CDS TBMG_00288 NC_012943.1 346889 348505 D hypothetical protein 346889..348505 Mycobacterium tuberculosis KZN 1435 8162460 YP_003030212.1 CDS TBMG_00289 NC_012943.1 348502 352494 D hypothetical protein 348502..352494 Mycobacterium tuberculosis KZN 1435 8162461 YP_003030213.1 CDS TBMG_00290 NC_012943.1 352491 352799 D PE family protein 352491..352799 Mycobacterium tuberculosis KZN 1435 8162462 YP_003030214.1 CDS TBMG_00291 NC_012943.1 352802 354343 D PPE family protein 352802..354343 Mycobacterium tuberculosis KZN 1435 8162463 YP_003030215.1 CDS TBMG_00292 NC_012943.1 354392 354685 D esat-6 like protein esxG 354392..354685 Mycobacterium tuberculosis KZN 1435 8162464 YP_003030216.1 CDS TBMG_00293 NC_012943.1 354715 355005 D low molecular weight protein antigen 7 esxH 354715..355005 Mycobacterium tuberculosis KZN 1435 8162465 YP_003030217.1 CDS TBMG_00294 NC_012943.1 355016 355903 D hypothetical protein 355016..355903 Mycobacterium tuberculosis KZN 1435 8162466 YP_003030218.1 CDS TBMG_00295 NC_012943.1 355950 357368 D hypothetical protein 355950..357368 Mycobacterium tuberculosis KZN 1435 8162467 YP_003030219.1 CDS TBMG_00296 NC_012943.1 357365 358750 D membrane-anchored mycosin mycP3 357365..358750 Mycobacterium tuberculosis KZN 1435 8162468 YP_003030220.1 CDS TBMG_00297 NC_012943.1 358747 359742 D hypothetical protein 358747..359742 Mycobacterium tuberculosis KZN 1435 8162469 YP_003030221.1 CDS TBMG_00298 NC_012943.1 359729 360931 R hypothetical protein complement(359729..360931) Mycobacterium tuberculosis KZN 1435 8162470 YP_003030222.1 CDS TBMG_00299 NC_012943.1 361038 361823 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 361038..361823 Mycobacterium tuberculosis KZN 1435 8162471 YP_003030223.1 CDS TBMG_00300 NC_012943.1 361812 362615 R hypothetical protein complement(361812..362615) Mycobacterium tuberculosis KZN 1435 8162472 YP_003030224.1 CDS TBMG_00301 NC_012943.1 362625 364031 R sulfatase complement(362625..364031) Mycobacterium tuberculosis KZN 1435 8162473 YP_003030225.1 CDS TBMG_00302 NC_012943.1 364201 366039 D hypothetical protein 364201..366039 Mycobacterium tuberculosis KZN 1435 8162474 YP_003030226.1 CDS TBMG_00303 NC_012943.1 366109 366336 D hypothetical protein 366109..366336 Mycobacterium tuberculosis KZN 1435 8162475 YP_003030227.1 CDS TBMG_00304 NC_012943.1 366333 366635 D hypothetical protein 366333..366635 Mycobacterium tuberculosis KZN 1435 8162476 YP_003030228.1 CDS TBMG_00305 NC_012943.1 366683 366904 D antitoxin 366683..366904 Mycobacterium tuberculosis KZN 1435 8162477 YP_003030229.1 CDS TBMG_00306 NC_012943.1 366901 367326 D toxin 366901..367326 Mycobacterium tuberculosis KZN 1435 8162478 YP_003030230.1 CDS TBMG_00307 NC_012943.1 367462 368094 D TetR family transcriptional regulator 367462..368094 Mycobacterium tuberculosis KZN 1435 8162479 YP_003030231.1 CDS TBMG_00308 NC_012943.1 368091 368999 D dehydrogenase/reductase 368091..368999 Mycobacterium tuberculosis KZN 1435 8162480 YP_003030232.1 CDS TBMG_00309 NC_012943.1 369007 378597 R PPE family protein complement(369007..378597) Mycobacterium tuberculosis KZN 1435 8162481 YP_003030233.1 CDS TBMG_00310 NC_012943.1 378800 379471 D oxidoreductase 378800..379471 Mycobacterium tuberculosis KZN 1435 8162482 YP_003030234.1 CDS TBMG_00311 NC_012943.1 379459 379941 R hypothetical protein complement(379459..379941) Mycobacterium tuberculosis KZN 1435 8162483 YP_003030235.1 CDS TBMG_00312 NC_012943.1 379999 380715 D hypothetical protein 379999..380715 Mycobacterium tuberculosis KZN 1435 8162484 YP_003030236.1 CDS TBMG_00313 NC_012943.1 380817 381473 D hypothetical protein 380817..381473 Mycobacterium tuberculosis KZN 1435 8162485 YP_003030237.1 CDS TBMG_00314 NC_012943.1 381543 382034 R hypothetical protein complement(381543..382034) Mycobacterium tuberculosis KZN 1435 8162486 YP_003030238.1 CDS TBMG_00315 NC_012943.1 382058 383287 D hypothetical protein 382058..383287 Mycobacterium tuberculosis KZN 1435 8162487 YP_003030239.1 CDS TBMG_00316 NC_012943.1 383442 385304 D hypothetical protein 383442..385304 Mycobacterium tuberculosis KZN 1435 8162488 YP_003030240.1 CDS TBMG_00317 NC_012943.1 385376 385762 D hypothetical protein 385376..385762 Mycobacterium tuberculosis KZN 1435 8162489 YP_003030241.1 CDS TBMG_00318 NC_012943.1 385765 386427 R hypothetical protein complement(385765..386427) Mycobacterium tuberculosis KZN 1435 8162490 YP_003030242.1 CDS TBMG_00319 NC_012943.1 386518 387372 D beta-1,3-glucanase precursor 386518..387372 Mycobacterium tuberculosis KZN 1435 8162491 YP_003030243.1 CDS TBMG_00320 NC_012943.1 387421 388035 D muconolactone isomerase 387421..388035 Mycobacterium tuberculosis KZN 1435 8162492 YP_003030244.1 CDS TBMG_00321 NC_012943.1 388059 388829 R glycerophosphoryl diester phosphodiesterase glpQ2 complement(388059..388829) Mycobacterium tuberculosis KZN 1435 8162333 YP_003030245.1 CDS TBMG_00322 NC_012943.1 389191 389985 R hypothetical protein complement(389191..389985) Mycobacterium tuberculosis KZN 1435 8162496 YP_003030246.1 CDS TBMG_00323 NC_012943.1 390034 390702 D catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 390034..390702 Mycobacterium tuberculosis KZN 1435 8162497 YP_003030247.1 CDS TBMG_00324 NC_012943.1 390774 391436 D hypothetical protein 390774..391436 Mycobacterium tuberculosis KZN 1435 8162498 YP_003030248.1 CDS dcd NC_012943.1 391468 392040 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 391468..392040 Mycobacterium tuberculosis KZN 1435 8162499 YP_003030249.1 CDS TBMG_00326 NC_012943.1 392146 393477 D UDP-glucose 6-dehydrogenase udgA 392146..393477 Mycobacterium tuberculosis KZN 1435 8162500 YP_003030250.1 CDS TBMG_00327 NC_012943.1 393466 394137 R hypothetical protein complement(393466..394137) Mycobacterium tuberculosis KZN 1435 8162501 YP_003030251.1 CDS TBMG_00328 NC_012943.1 394238 394918 D transcriptional regulator, arsR-family 394238..394918 Mycobacterium tuberculosis KZN 1435 8162502 YP_003030252.1 CDS TBMG_00329 NC_012943.1 394925 395149 D hypothetical protein 394925..395149 Mycobacterium tuberculosis KZN 1435 8162503 YP_003030253.1 CDS TBMG_00330 NC_012943.1 395159 395614 D hypothetical protein 395159..395614 Mycobacterium tuberculosis KZN 1435 8162504 YP_003030254.1 CDS TBMG_00331 NC_012943.1 395582 396931 R cytochrome P450 135A1 cyp135A1 complement(395582..396931) Mycobacterium tuberculosis KZN 1435 8162505 YP_003030255.1 CDS TBMG_00332 NC_012943.1 396997 397599 D TetR family transcriptional regulator 396997..397599 Mycobacterium tuberculosis KZN 1435 8162506 YP_003030256.1 CDS TBMG_00333 NC_012943.1 397580 398206 R hypothetical protein complement(397580..398206) Mycobacterium tuberculosis KZN 1435 8162507 YP_003030257.1 CDS TBMG_00334 NC_012943.1 398233 398973 R hypothetical protein complement(398233..398973) Mycobacterium tuberculosis KZN 1435 8162508 YP_003030258.1 CDS TBMG_00335 NC_012943.1 399087 400253 D dehydrogenase/reductase 399087..400253 Mycobacterium tuberculosis KZN 1435 8162509 YP_003030259.1 CDS TBMG_00336 NC_012943.1 400328 401113 D hypothetical protein 400328..401113 Mycobacterium tuberculosis KZN 1435 8162510 YP_003030260.1 CDS TBMG_00337 NC_012943.1 401140 401514 D hypothetical protein 401140..401514 Mycobacterium tuberculosis KZN 1435 8162511 YP_003030261.1 CDS TBMG_00338 NC_012943.1 401544 402410 D alpha-D-glucose-1-phosphate thymidylyltransferase 401544..402410 Mycobacterium tuberculosis KZN 1435 8162512 YP_003030262.1 CDS TBMG_00339 NC_012943.1 402421 402936 R PE family protein complement(402421..402936) Mycobacterium tuberculosis KZN 1435 8162513 YP_003030263.1 CDS TBMG_00340 NC_012943.1 403054 404589 D hypothetical protein 403054..404589 Mycobacterium tuberculosis KZN 1435 8162514 YP_003030264.1 CDS TBMG_00341 NC_012943.1 404759 406048 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase complement(404759..406048) Mycobacterium tuberculosis KZN 1435 8162515 YP_003030265.1 CDS TBMG_00342 NC_012943.1 406079 408727 R iron-sulfur-binding reductase complement(406079..408727) Mycobacterium tuberculosis KZN 1435 8162516 YP_003030266.1 CDS TBMG_00343 NC_012943.1 408836 411334 R transcriptional regulator complement(408836..411334) Mycobacterium tuberculosis KZN 1435 8162517 YP_003030267.1 CDS TBMG_00344 NC_012943.1 411520 412059 D hypothetical protein 411520..412059 Mycobacterium tuberculosis KZN 1435 8162518 YP_003030268.1 CDS TBMG_00345 NC_012943.1 412242 413687 D isoniazid inductible protein iniB 412242..413687 Mycobacterium tuberculosis KZN 1435 8162519 YP_003030269.1 CDS TBMG_00346 NC_012943.1 413724 415646 D isoniazid inductible protein iniA 413724..415646 Mycobacterium tuberculosis KZN 1435 8162520 YP_003030270.1 CDS TBMG_00347 NC_012943.1 415643 417124 D isoniazid inductible protein iniC 415643..417124 Mycobacterium tuberculosis KZN 1435 8162521 YP_003030271.1 CDS TBMG_00348 NC_012943.1 417267 417827 R hypothetical protein complement(417267..417827) Mycobacterium tuberculosis KZN 1435 8162522 YP_003030272.1 CDS TBMG_00349 NC_012943.1 417930 418346 D hypothetical protein 417930..418346 Mycobacterium tuberculosis KZN 1435 8162523 YP_003030273.1 CDS TBMG_00350 NC_012943.1 418388 419851 R L-asparagine permease ansP2 complement(418388..419851) Mycobacterium tuberculosis KZN 1435 8162524 YP_003030274.1 CDS TBMG_00351 NC_012943.1 420190 421176 D hypothetical protein 420190..421176 Mycobacterium tuberculosis KZN 1435 8162525 YP_003030275.1 CDS TBMG_00352 NC_012943.1 421179 421832 D transcriptional regulator 421179..421832 Mycobacterium tuberculosis KZN 1435 8162526 YP_003030276.1 CDS TBMG_00353 NC_012943.1 421835 422494 D hypothetical protein 421835..422494 Mycobacterium tuberculosis KZN 1435 8162527 YP_003030277.1 CDS dnaK NC_012943.1 422721 424598 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 422721..424598 Mycobacterium tuberculosis KZN 1435 8162528 YP_003030278.1 CDS TBMG_00355 NC_012943.1 424595 425302 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 424595..425302 Mycobacterium tuberculosis KZN 1435 8162529 YP_003030279.1 CDS TBMG_00356 NC_012943.1 425338 426525 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 425338..426525 Mycobacterium tuberculosis KZN 1435 8162530 YP_003030280.1 CDS TBMG_00357 NC_012943.1 426525 426905 D merR-family heat shock protein transcriptional repressor hspR 426525..426905 Mycobacterium tuberculosis KZN 1435 8162531 YP_003030281.1 CDS TBMG_00358 NC_012943.1 427081 427632 R PPE family protein complement(427081..427632) Mycobacterium tuberculosis KZN 1435 8162532 YP_003030282.1 CDS TBMG_00359 NC_012943.1 427715 437542 R PPE family protein complement(427715..437542) Mycobacterium tuberculosis KZN 1435 8162533 YP_003030283.1 CDS TBMG_00360 NC_012943.1 437693 438337 R hypothetical protein complement(437693..438337) Mycobacterium tuberculosis KZN 1435 8162534 YP_003030284.1 CDS TBMG_00361 NC_012943.1 438334 439632 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(438334..439632) Mycobacterium tuberculosis KZN 1435 8162535 YP_003030285.1 CDS TBMG_00362 NC_012943.1 439723 440370 D hypothetical protein 439723..440370 Mycobacterium tuberculosis KZN 1435 8162536 YP_003030286.1 CDS TBMG_00363 NC_012943.1 440381 441160 D hypothetical protein 440381..441160 Mycobacterium tuberculosis KZN 1435 8162537 YP_003030287.1 CDS TBMG_00364 NC_012943.1 441165 441602 R hypothetical protein complement(441165..441602) Mycobacterium tuberculosis KZN 1435 8162538 YP_003030288.1 CDS TBMG_00365 NC_012943.1 441685 442512 D hypothetical protein 441685..442512 Mycobacterium tuberculosis KZN 1435 8162539 YP_003030289.1 CDS TBMG_00366 NC_012943.1 442734 444116 D hypothetical protein 442734..444116 Mycobacterium tuberculosis KZN 1435 8162540 YP_003030290.1 CDS TBMG_00367 NC_012943.1 444128 445162 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(444128..445162) Mycobacterium tuberculosis KZN 1435 8162541 YP_003030291.1 CDS TBMG_00368 NC_012943.1 445258 445941 D hypothetical protein 445258..445941 Mycobacterium tuberculosis KZN 1435 8162542 YP_003030292.1 CDS TBMG_00369 NC_012943.1 445930 447060 R hypothetical protein complement(445930..447060) Mycobacterium tuberculosis KZN 1435 8162543 YP_003030293.1 CDS TBMG_00370 NC_012943.1 447085 447678 R hypothetical protein complement(447085..447678) Mycobacterium tuberculosis KZN 1435 8162544 YP_003030294.1 CDS TBMG_00371 NC_012943.1 447707 448096 R hypothetical protein complement(447707..448096) Mycobacterium tuberculosis KZN 1435 8162545 YP_003030295.1 CDS TBMG_00372 NC_012943.1 448177 449388 R hypothetical protein complement(448177..449388) Mycobacterium tuberculosis KZN 1435 8162546 YP_003030296.1 CDS TBMG_00373 NC_012943.1 449394 449996 R membrane oxidoreductase complement(449394..449996) Mycobacterium tuberculosis KZN 1435 8162547 YP_003030297.1 CDS TBMG_00374 NC_012943.1 450010 450906 R oxidoreductase complement(450010..450906) Mycobacterium tuberculosis KZN 1435 8162548 YP_003030298.1 CDS TBMG_00375 NC_012943.1 450903 451496 R hypothetical protein complement(450903..451496) Mycobacterium tuberculosis KZN 1435 8162549 YP_003030299.1 CDS TBMG_00376 NC_012943.1 451493 452248 R hypothetical protein complement(451493..452248) Mycobacterium tuberculosis KZN 1435 8162550 YP_003030300.1 CDS TBMG_00377 NC_012943.1 452267 454666 R carbon monoxyde dehydrogenase large subunit complement(452267..454666) Mycobacterium tuberculosis KZN 1435 8162551 YP_003030301.1 CDS TBMG_00378 NC_012943.1 454663 455142 R carbon monoxyde dehydrogenase small subunit complement(454663..455142) Mycobacterium tuberculosis KZN 1435 8162552 YP_003030302.1 CDS TBMG_00379 NC_012943.1 455157 456059 R carbon monoxyde dehydrogenase subunit medium complement(455157..456059) Mycobacterium tuberculosis KZN 1435 8162553 YP_003030303.1 CDS TBMG_00380 NC_012943.1 456234 456449 D preprotein translocase subunit secE2 456234..456449 Mycobacterium tuberculosis KZN 1435 8162554 YP_003030304.1 CDS TBMG_00381 NC_012943.1 456525 457187 R RNA methyltransferase complement(456525..457187) Mycobacterium tuberculosis KZN 1435 8162555 YP_003030305.1 CDS TBMG_00382 NC_012943.1 457172 458080 R hypothetical protein complement(457172..458080) Mycobacterium tuberculosis KZN 1435 8162556 YP_003030306.1 CDS pyrE NC_012943.1 458098 458637 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(458098..458637) Mycobacterium tuberculosis KZN 1435 8162557 YP_003030307.1 CDS TBMG_00384 NC_012943.1 458718 459572 R hypothetical protein complement(458718..459572) Mycobacterium tuberculosis KZN 1435 8162558 YP_003030308.1 CDS TBMG_00385 NC_012943.1 459713 462259 R endopeptidase subunit ATP binding protein B clpB complement(459713..462259) Mycobacterium tuberculosis KZN 1435 8162559 YP_003030309.1 CDS TBMG_00386 NC_012943.1 462287 463564 D monooxygenase 462287..463564 Mycobacterium tuberculosis KZN 1435 8162560 YP_003030310.1 CDS TBMG_00387 NC_012943.1 463668 466925 D transcriptional regulator, luxR/uhpA-family 463668..466925 Mycobacterium tuberculosis KZN 1435 8162561 YP_003030311.1 CDS TBMG_00388 NC_012943.1 466929 468260 R PPE family protein complement(466929..468260) Mycobacterium tuberculosis KZN 1435 8162562 YP_003030312.1 CDS purT NC_012943.1 468594 469853 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 468594..469853 Mycobacterium tuberculosis KZN 1435 8162563 YP_003030313.1 CDS TBMG_00390 NC_012943.1 469850 470272 D hypothetical protein 469850..470272 Mycobacterium tuberculosis KZN 1435 8162564 YP_003030314.1 CDS TBMG_00391 NC_012943.1 470269 471489 D O-succinylhomoserine sulfhydrylase 470269..471489 Mycobacterium tuberculosis KZN 1435 8162565 YP_003030315.1 CDS TBMG_00392 NC_012943.1 471486 472898 R membrane NADH dehydrogenase ndhA complement(471486..472898) Mycobacterium tuberculosis KZN 1435 8162566 YP_003030316.1 CDS TBMG_00393 NC_012943.1 473040 474365 D hypothetical protein 473040..474365 Mycobacterium tuberculosis KZN 1435 8162567 YP_003030317.1 CDS TBMG_00394 NC_012943.1 474381 475100 R hypothetical protein complement(474381..475100) Mycobacterium tuberculosis KZN 1435 8162568 YP_003030318.1 CDS TBMG_00395 NC_012943.1 475199 475603 D hypothetical protein 475199..475603 Mycobacterium tuberculosis KZN 1435 8162569 YP_003030319.1 CDS TBMG_00396 NC_012943.1 475585 476001 D hypothetical protein 475585..476001 Mycobacterium tuberculosis KZN 1435 8162570 YP_003030320.1 CDS TBMG_00397 NC_012943.1 476075 476443 D hypothetical protein 476075..476443 Mycobacterium tuberculosis KZN 1435 8162571 YP_003030321.1 CDS TBMG_00398 NC_012943.1 476653 476901 D hypothetical protein 476653..476901 Mycobacterium tuberculosis KZN 1435 8162572 YP_003030322.1 CDS TBMG_00399 NC_012943.1 476938 477579 R hypothetical protein complement(476938..477579) Mycobacterium tuberculosis KZN 1435 8162573 YP_003030323.1 CDS TBMG_00400 NC_012943.1 477586 478815 R hypothetical protein complement(477586..478815) Mycobacterium tuberculosis KZN 1435 8162574 YP_003030324.1 CDS TBMG_00401 NC_012943.1 478825 480012 R acyl-CoA dehydrogenase complement(478825..480012) Mycobacterium tuberculosis KZN 1435 8162575 YP_003030325.1 CDS TBMG_00402 NC_012943.1 480048 480419 D hypothetical protein 480048..480419 Mycobacterium tuberculosis KZN 1435 8162576 YP_003030326.1 CDS TBMG_00403 NC_012943.1 480614 483490 R transmembrane transporter mmpL1 complement(480614..483490) Mycobacterium tuberculosis KZN 1435 8162577 YP_003030327.1 CDS TBMG_00404 NC_012943.1 483487 483915 R hypothetical protein complement(483487..483915) Mycobacterium tuberculosis KZN 1435 8162578 YP_003030328.1 CDS TBMG_00405 NC_012943.1 484236 485993 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 484236..485993 Mycobacterium tuberculosis KZN 1435 8162579 YP_003030329.1 CDS TBMG_00406 NC_012943.1 485990 490198 D membrane bound polyketide synthase pks6 485990..490198 Mycobacterium tuberculosis KZN 1435 8162580 YP_003030330.1 CDS TBMG_00407 NC_012943.1 490146 490964 R beta lactamase like protein complement(490146..490964) Mycobacterium tuberculosis KZN 1435 8164241 YP_003030331.1 CDS TBMG_00408 NC_012943.1 491042 492052 D F420-dependent glucose-6-phosphate dehydrogenase 491042..492052 Mycobacterium tuberculosis KZN 1435 8164242 YP_003030332.1 CDS TBMG_00409 NC_012943.1 492045 494117 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 492045..494117 Mycobacterium tuberculosis KZN 1435 8164243 YP_003030333.1 CDS TBMG_00410 NC_012943.1 494110 495267 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 494110..495267 Mycobacterium tuberculosis KZN 1435 8164244 YP_003030334.1 CDS TBMG_00411 NC_012943.1 495321 497573 R serine/threonine-protein kinase pknG complement(495321..497573) Mycobacterium tuberculosis KZN 1435 8164245 YP_003030335.1 CDS TBMG_00412 NC_012943.1 497573 498559 R glutamine-binding lipoprotein glnH complement(497573..498559) Mycobacterium tuberculosis KZN 1435 8164246 YP_003030336.1 CDS TBMG_00413 NC_012943.1 498559 499878 R hypothetical protein complement(498559..499878) Mycobacterium tuberculosis KZN 1435 8164247 YP_003030337.1 CDS TBMG_00414 NC_012943.1 499972 500625 D mutator protein mutT3 499972..500625 Mycobacterium tuberculosis KZN 1435 8164248 YP_003030338.1 CDS thiE NC_012943.1 500609 501277 R Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase complement(500609..501277) Mycobacterium tuberculosis KZN 1435 8164249 YP_003030339.1 CDS TBMG_00416 NC_012943.1 501407 502429 D thiamine biosynthesis oxidoreductase thiO 501407..502429 Mycobacterium tuberculosis KZN 1435 8164250 YP_003030340.1 CDS TBMG_00417 NC_012943.1 502426 502632 D with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 502426..502632 Mycobacterium tuberculosis KZN 1435 8164251 YP_003030341.1 CDS thiG NC_012943.1 502625 503383 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 502625..503383 Mycobacterium tuberculosis KZN 1435 8164252 YP_003030342.1 CDS TBMG_03984 NC_012943.1 503405 503557 D hypothetical protein 503405..503557 Mycobacterium tuberculosis KZN 1435 8164253 YP_003030343.1 CDS TBMG_00419 NC_012943.1 503755 505257 D lipoprotein aminopeptidase lpqL 503755..505257 Mycobacterium tuberculosis KZN 1435 8164254 YP_003030344.1 CDS TBMG_00420 NC_012943.1 505345 506841 D lipoprotein peptidase lpqM 505345..506841 Mycobacterium tuberculosis KZN 1435 8164255 YP_003030345.1 CDS TBMG_00421 NC_012943.1 506820 507230 R hypothetical protein complement(506820..507230) Mycobacterium tuberculosis KZN 1435 8164256 YP_003030346.1 CDS TBMG_00422 NC_012943.1 507391 508020 R hypothetical protein complement(507391..508020) Mycobacterium tuberculosis KZN 1435 8164257 YP_003030347.1 CDS TBMG_00423 NC_012943.1 508017 508844 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(508017..508844) Mycobacterium tuberculosis KZN 1435 8164258 YP_003030348.1 CDS TBMG_00424 NC_012943.1 508841 510484 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(508841..510484) Mycobacterium tuberculosis KZN 1435 8164259 YP_003030349.1 CDS TBMG_00425 NC_012943.1 510636 510914 R hypothetical protein complement(510636..510914) Mycobacterium tuberculosis KZN 1435 8164260 YP_003030350.1 CDS TBMG_00426 NC_012943.1 510961 515580 R metal cation transporting P-type ATPase ctpH complement(510961..515580) Mycobacterium tuberculosis KZN 1435 8164261 YP_003030351.1 CDS TBMG_00427 NC_012943.1 515632 516207 R hypothetical protein complement(515632..516207) Mycobacterium tuberculosis KZN 1435 8164262 YP_003030352.1 CDS TBMG_00428 NC_012943.1 516276 517151 R exodeoxyribonuclease III protein xthA complement(516276..517151) Mycobacterium tuberculosis KZN 1435 8164263 YP_003030353.1 CDS TBMG_00429 NC_012943.1 517154 518062 R hypothetical protein complement(517154..518062) Mycobacterium tuberculosis KZN 1435 8164264 YP_003030354.1 CDS def NC_012943.1 518062 518655 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(518062..518655) Mycobacterium tuberculosis KZN 1435 8164265 YP_003030355.1 CDS TBMG_00431 NC_012943.1 518848 519300 D hypothetical protein 518848..519300 Mycobacterium tuberculosis KZN 1435 8164266 YP_003030356.1 CDS TBMG_00432 NC_012943.1 519332 519826 D tuberculin related peptide 519332..519826 Mycobacterium tuberculosis KZN 1435 8164267 YP_003030357.1 CDS TBMG_00433 NC_012943.1 519859 520581 D periplasmic superoxide dismutase [Cu-Zn] sodC 519859..520581 Mycobacterium tuberculosis KZN 1435 8164268 YP_003030358.1 CDS TBMG_00434 NC_012943.1 520583 521713 D ATP-dependent carboxylate-amine ligase; carboxylate-amine ligase 520583..521713 Mycobacterium tuberculosis KZN 1435 8164269 YP_003030359.1 CDS TBMG_00435 NC_012943.1 521770 522426 D hypothetical protein 521770..522426 Mycobacterium tuberculosis KZN 1435 8164270 YP_003030360.1 CDS TBMG_00436 NC_012943.1 522606 524792 R ATPase complement(522606..524792) Mycobacterium tuberculosis KZN 1435 8164271 YP_003030361.1 CDS TBMG_00437 NC_012943.1 524789 525649 R CDP-diacylglycerol-serine O-phosphatidyltransferase pssA complement(524789..525649) Mycobacterium tuberculosis KZN 1435 8164272 YP_003030362.1 CDS TBMG_00438 NC_012943.1 525646 526341 R catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase complement(525646..526341) Mycobacterium tuberculosis KZN 1435 8164273 YP_003030363.1 CDS TBMG_00439 NC_012943.1 526402 527619 R molybdopterin biosynthesis protein moeA2 complement(526402..527619) Mycobacterium tuberculosis KZN 1435 8164274 YP_003030364.1 CDS TBMG_00440 NC_012943.1 527638 528573 R short chain dehydrogenase complement(527638..528573) Mycobacterium tuberculosis KZN 1435 8164275 YP_003030365.1 CDS groEL NC_012943.1 528867 530489 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 528867..530489 Mycobacterium tuberculosis KZN 1435 8164276 YP_003030366.1 CDS TBMG_00442 NC_012943.1 530555 530983 R hypothetical protein complement(530555..530983) Mycobacterium tuberculosis KZN 1435 8164277 YP_003030367.1 CDS TBMG_00443 NC_012943.1 531010 532473 R PPE family protein complement(531010..532473) Mycobacterium tuberculosis KZN 1435 8164278 YP_003030368.1 CDS TBMG_00444 NC_012943.1 532613 533170 D hypothetical protein 532613..533170 Mycobacterium tuberculosis KZN 1435 8164279 YP_003030369.1 CDS TBMG_00445 NC_012943.1 533350 534048 R hypothetical protein complement(533350..534048) Mycobacterium tuberculosis KZN 1435 8164280 YP_003030370.1 CDS TBMG_00446 NC_012943.1 534092 534655 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; RNA polymerase sigma factor SigK complement(534092..534655) Mycobacterium tuberculosis KZN 1435 8164281 YP_003030371.1 CDS TBMG_03985 NC_012943.1 534704 534892 R hypothetical protein complement(534704..534892) Mycobacterium tuberculosis KZN 1435 8164282 YP_003030372.1 CDS TBMG_00447 NC_012943.1 534950 535486 R hypothetical protein complement(534950..535486) Mycobacterium tuberculosis KZN 1435 8164283 YP_003030373.1 CDS TBMG_00448 NC_012943.1 535483 536766 R cyclopropane-fatty-acyl-phospholipid synthase ufaA1 complement(535483..536766) Mycobacterium tuberculosis KZN 1435 8164284 YP_003030374.1 CDS TBMG_00449 NC_012943.1 536763 537428 R hypothetical protein complement(536763..537428) Mycobacterium tuberculosis KZN 1435 8164285 YP_003030375.1 CDS TBMG_00450 NC_012943.1 537488 538807 R hypothetical protein complement(537488..538807) Mycobacterium tuberculosis KZN 1435 8164286 YP_003030376.1 CDS TBMG_00451 NC_012943.1 538847 541750 R transmembrane transporter mmpL4 complement(538847..541750) Mycobacterium tuberculosis KZN 1435 8164287 YP_003030377.1 CDS TBMG_00452 NC_012943.1 541747 542169 R hypothetical protein complement(541747..542169) Mycobacterium tuberculosis KZN 1435 8164288 YP_003030378.1 CDS TBMG_00453 NC_012943.1 542350 543111 D transcriptional regulator 542350..543111 Mycobacterium tuberculosis KZN 1435 8164289 YP_003030379.1 CDS TBMG_00454 NC_012943.1 543433 544989 D PPE family protein 543433..544989 Mycobacterium tuberculosis KZN 1435 8164290 YP_003030380.1 CDS TBMG_00455 NC_012943.1 544995 545549 R hypothetical protein complement(544995..545549) Mycobacterium tuberculosis KZN 1435 8164291 YP_003030381.1 CDS TBMG_00456 NC_012943.1 545634 546161 R hypothetical protein complement(545634..546161) Mycobacterium tuberculosis KZN 1435 8164292 YP_003030382.1 CDS TBMG_00457 NC_012943.1 546148 547062 R catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(546148..547062) Mycobacterium tuberculosis KZN 1435 8164293 YP_003030383.1 CDS TBMG_03986 NC_012943.1 547335 547616 R toxin complement(547335..547616) Mycobacterium tuberculosis KZN 1435 8164294 YP_003030384.1 CDS TBMG_03987 NC_012943.1 547603 547776 R antitoxin complement(547603..547776) Mycobacterium tuberculosis KZN 1435 8164295 YP_003030385.1 CDS TBMG_00459 NC_012943.1 547845 549875 R peptidase complement(547845..549875) Mycobacterium tuberculosis KZN 1435 8164296 YP_003030386.1 CDS TBMG_00460 NC_012943.1 549934 551457 D aldehyde dehydrogenase 549934..551457 Mycobacterium tuberculosis KZN 1435 8164297 YP_003030387.1 CDS TBMG_00461 NC_012943.1 551457 551948 D hypothetical protein 551457..551948 Mycobacterium tuberculosis KZN 1435 8164298 YP_003030388.1 CDS TBMG_00462 NC_012943.1 551969 552247 D hydrophobic protein 551969..552247 Mycobacterium tuberculosis KZN 1435 8164299 YP_003030389.1 CDS TBMG_00463 NC_012943.1 552240 552809 D hypothetical protein 552240..552809 Mycobacterium tuberculosis KZN 1435 8164300 YP_003030390.1 CDS TBMG_00464 NC_012943.1 552873 554267 D E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; dihydrolipoamide dehydrogenase 552873..554267 Mycobacterium tuberculosis KZN 1435 8164301 YP_003030391.1 CDS TBMG_00465 NC_012943.1 554275 554568 D hypothetical protein 554275..554568 Mycobacterium tuberculosis KZN 1435 8164302 YP_003030392.1 CDS TBMG_00466 NC_012943.1 554572 555144 R hypothetical protein complement(554572..555144) Mycobacterium tuberculosis KZN 1435 8164303 YP_003030393.1 CDS TBMG_00467 NC_012943.1 555141 556565 R transcriptional regulator complement(555141..556565) Mycobacterium tuberculosis KZN 1435 8164304 YP_003030394.1 CDS TBMG_00468 NC_012943.1 556717 557511 D hypothetical protein 556717..557511 Mycobacterium tuberculosis KZN 1435 8164305 YP_003030395.1 CDS TBMG_00469 NC_012943.1 557786 559072 D isocitrate lyase icl 557786..559072 Mycobacterium tuberculosis KZN 1435 8164306 YP_003030396.1 CDS TBMG_00470 NC_012943.1 559154 560014 D converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 559154..560014 Mycobacterium tuberculosis KZN 1435 8164307 YP_003030397.1 CDS TBMG_00471 NC_012943.1 560129 561007 D mycolic acid synthase umaA 560129..561007 Mycobacterium tuberculosis KZN 1435 8164308 YP_003030398.1 CDS TBMG_00472 NC_012943.1 561107 561970 R mycolic acid synthase PcaA complement(561107..561970) Mycobacterium tuberculosis KZN 1435 8164309 YP_003030399.1 CDS TBMG_00473 NC_012943.1 562113 562553 R hypothetical protein complement(562113..562553) Mycobacterium tuberculosis KZN 1435 8164310 YP_003030400.1 CDS TBMG_00474 NC_012943.1 562484 562972 R hypothetical protein complement(562484..562972) Mycobacterium tuberculosis KZN 1435 8164311 YP_003030401.1 CDS TBMG_00475 NC_012943.1 562982 563752 R TetR family transcriptional regulator complement(562982..563752) Mycobacterium tuberculosis KZN 1435 8164312 YP_003030402.1 CDS TBMG_00476 NC_012943.1 563823 565193 D hypothetical protein 563823..565193 Mycobacterium tuberculosis KZN 1435 8164313 YP_003030403.1 CDS TBMG_00477 NC_012943.1 565280 565702 D transcriptional regulator 565280..565702 Mycobacterium tuberculosis KZN 1435 8164314 YP_003030404.1 CDS TBMG_00478 NC_012943.1 566041 566655 D iron-regulated heparin binding hemagglutinin hbhA 566041..566655 Mycobacterium tuberculosis KZN 1435 8164315 YP_003030405.1 CDS TBMG_00479 NC_012943.1 566767 567030 D hypothetical protein 566767..567030 Mycobacterium tuberculosis KZN 1435 8164316 YP_003030406.1 CDS TBMG_00480 NC_012943.1 567035 567481 D hypothetical protein 567035..567481 Mycobacterium tuberculosis KZN 1435 8164317 YP_003030407.1 CDS TBMG_00481 NC_012943.1 567481 568155 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 567481..568155 Mycobacterium tuberculosis KZN 1435 8164318 YP_003030408.1 CDS TBMG_00482 NC_012943.1 568180 569226 R hypothetical protein complement(568180..569226) Mycobacterium tuberculosis KZN 1435 8164319 YP_003030409.1 CDS TBMG_00483 NC_012943.1 569223 570065 R amidohydrolase complement(569223..570065) Mycobacterium tuberculosis KZN 1435 8164320 YP_003030410.1 CDS TBMG_00484 NC_012943.1 570191 570715 R hypothetical protein complement(570191..570715) Mycobacterium tuberculosis KZN 1435 8162581 YP_003030411.1 CDS murB NC_012943.1 570742 571851 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 570742..571851 Mycobacterium tuberculosis KZN 1435 8162582 YP_003030412.1 CDS TBMG_00486 NC_012943.1 571913 573268 D hypothetical protein 571913..573268 Mycobacterium tuberculosis KZN 1435 8164159 YP_003030413.1 CDS TBMG_00487 NC_012943.1 573249 574004 R short-chain type oxidoreductase complement(573249..574004) Mycobacterium tuberculosis KZN 1435 8164160 YP_003030414.1 CDS TBMG_00488 NC_012943.1 574187 575503 D transcriptional regulator 574187..575503 Mycobacterium tuberculosis KZN 1435 8164161 YP_003030415.1 CDS TBMG_00489 NC_012943.1 575551 576993 D mannosyltransferase 575551..576993 Mycobacterium tuberculosis KZN 1435 8164162 YP_003030416.1 CDS TBMG_00490 NC_012943.1 576990 577541 D hypothetical protein 576990..577541 Mycobacterium tuberculosis KZN 1435 8164163 YP_003030417.1 CDS TBMG_00491 NC_012943.1 577846 578472 D hypothetical protein 577846..578472 Mycobacterium tuberculosis KZN 1435 8164164 YP_003030418.1 CDS gpmA NC_012943.1 578608 579378 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 578608..579378 Mycobacterium tuberculosis KZN 1435 8164165 YP_003030419.1 CDS TBMG_00493 NC_012943.1 579552 580784 D two component system sensor histidine kinase senX3 579552..580784 Mycobacterium tuberculosis KZN 1435 8164166 YP_003030420.1 CDS TBMG_00494 NC_012943.1 580700 580906 R hypothetical protein complement(580700..580906) Mycobacterium tuberculosis KZN 1435 8164167 YP_003030421.1 CDS TBMG_00495 NC_012943.1 580988 581671 D two component system sensor protein regX3 580988..581671 Mycobacterium tuberculosis KZN 1435 8164168 YP_003030422.1 CDS TBMG_00496 NC_012943.1 581668 583557 R oxidoreductase gmc-type complement(581668..583557) Mycobacterium tuberculosis KZN 1435 8164169 YP_003030423.1 CDS TBMG_00497 NC_012943.1 583554 583883 R hypothetical protein complement(583554..583883) Mycobacterium tuberculosis KZN 1435 8164170 YP_003030424.1 CDS TBMG_00498 NC_012943.1 583880 584869 R hypothetical protein complement(583880..584869) Mycobacterium tuberculosis KZN 1435 8164171 YP_003030425.1 CDS TBMG_00499 NC_012943.1 584874 585602 D GntR family transcriptional regulator 584874..585602 Mycobacterium tuberculosis KZN 1435 8164172 YP_003030426.1 CDS TBMG_00500 NC_012943.1 585603 586493 R hypothetical protein complement(585603..586493) Mycobacterium tuberculosis KZN 1435 8164173 YP_003030427.1 CDS TBMG_00501 NC_012943.1 586525 587559 D hypothetical protein 586525..587559 Mycobacterium tuberculosis KZN 1435 8164174 YP_003030428.1 CDS TBMG_00502 NC_012943.1 587556 588488 D hypothetical protein 587556..588488 Mycobacterium tuberculosis KZN 1435 8164175 YP_003030429.1 CDS TBMG_00503 NC_012943.1 588504 589346 D hypothetical protein 588504..589346 Mycobacterium tuberculosis KZN 1435 8164176 YP_003030430.1 CDS TBMG_00504 NC_012943.1 589362 590237 D hypothetical protein 589362..590237 Mycobacterium tuberculosis KZN 1435 8164177 YP_003030431.1 CDS TBMG_00505 NC_012943.1 590262 591149 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 590262..591149 Mycobacterium tuberculosis KZN 1435 8164178 YP_003030432.1 CDS TBMG_00506 NC_012943.1 591290 591526 D hypothetical protein 591290..591526 Mycobacterium tuberculosis KZN 1435 8164179 YP_003030433.1 CDS TBMG_00507 NC_012943.1 591570 591755 D hypothetical protein 591570..591755 Mycobacterium tuberculosis KZN 1435 8164180 YP_003030434.1 CDS TBMG_00508 NC_012943.1 591833 592963 D UDP-glucose 4-epimerase galE2 591833..592963 Mycobacterium tuberculosis KZN 1435 8164181 YP_003030435.1 CDS TBMG_00509 NC_012943.1 592970 594046 D hypothetical protein 592970..594046 Mycobacterium tuberculosis KZN 1435 8164182 YP_003030436.1 CDS TBMG_00510 NC_012943.1 594050 595018 R cyclopropane-fatty-acyl-phospholipid synthase 2 cmaA2 complement(594050..595018) Mycobacterium tuberculosis KZN 1435 8164183 YP_003030437.1 CDS TBMG_00511 NC_012943.1 594981 595481 R hypothetical protein complement(594981..595481) Mycobacterium tuberculosis KZN 1435 8164184 YP_003030438.1 CDS TBMG_00512 NC_012943.1 595643 596764 R phosphoserine phosphatase serB1 complement(595643..596764) Mycobacterium tuberculosis KZN 1435 8164185 YP_003030439.1 CDS TBMG_00513 NC_012943.1 596938 597381 D hypothetical protein 596938..597381 Mycobacterium tuberculosis KZN 1435 8164186 YP_003030440.1 CDS TBMG_00514 NC_012943.1 597378 600284 D transmembrane transporter mmpL2 597378..600284 Mycobacterium tuberculosis KZN 1435 8164187 YP_003030441.1 CDS TBMG_00515 NC_012943.1 600277 600570 D hypothetical protein 600277..600570 Mycobacterium tuberculosis KZN 1435 8164188 YP_003030442.1 CDS hemA NC_012943.1 600620 602026 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 600620..602026 Mycobacterium tuberculosis KZN 1435 8164189 YP_003030443.1 CDS hemC NC_012943.1 602027 602965 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 602027..602965 Mycobacterium tuberculosis KZN 1435 8164190 YP_003030444.1 CDS TBMG_00518 NC_012943.1 602989 604695 D uroporphyrin-III C-methyltransferase 602989..604695 Mycobacterium tuberculosis KZN 1435 8164191 YP_003030445.1 CDS TBMG_00519 NC_012943.1 604781 605770 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 604781..605770 Mycobacterium tuberculosis KZN 1435 8164192 YP_003030446.1 CDS TBMG_00520 NC_012943.1 605783 606331 D hypothetical protein 605783..606331 Mycobacterium tuberculosis KZN 1435 8164193 YP_003030447.1 CDS TBMG_00521 NC_012943.1 606328 606627 D hypothetical protein 606328..606627 Mycobacterium tuberculosis KZN 1435 8164194 YP_003030448.1 CDS TBMG_00522 NC_012943.1 606706 608241 D hypothetical protein 606706..608241 Mycobacterium tuberculosis KZN 1435 8164195 YP_003030449.1 CDS TBMG_00523 NC_012943.1 608238 608714 R hypothetical protein complement(608238..608714) Mycobacterium tuberculosis KZN 1435 8164196 YP_003030450.1 CDS TBMG_00524 NC_012943.1 608925 610235 D membrane acyltransferase 608925..610235 Mycobacterium tuberculosis KZN 1435 8164197 YP_003030451.1 CDS TBMG_00525 NC_012943.1 610367 611062 D hypothetical protein 610367..611062 Mycobacterium tuberculosis KZN 1435 8164198 YP_003030452.1 CDS TBMG_00526 NC_012943.1 611351 612253 R hypothetical protein complement(611351..612253) Mycobacterium tuberculosis KZN 1435 8164199 YP_003030453.1 CDS TBMG_00527 NC_012943.1 612434 612784 D methyltransferase/methylase 612434..612784 Mycobacterium tuberculosis KZN 1435 8164200 YP_003030454.1 CDS TBMG_00528 NC_012943.1 612777 613082 D methyltransferase/methylase 612777..613082 Mycobacterium tuberculosis KZN 1435 8164201 YP_003030455.1 CDS TBMG_00529 NC_012943.1 613217 614521 D gabA permease gabP 613217..614521 Mycobacterium tuberculosis KZN 1435 8164202 YP_003030456.1 CDS TBMG_00530 NC_012943.1 614505 614909 R hypothetical protein complement(614505..614909) Mycobacterium tuberculosis KZN 1435 8164203 YP_003030457.1 CDS TBMG_00531 NC_012943.1 615014 616402 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 615014..616402 Mycobacterium tuberculosis KZN 1435 8164204 YP_003030458.1 CDS TBMG_00532 NC_012943.1 616402 617010 D hypothetical protein 616402..617010 Mycobacterium tuberculosis KZN 1435 8164205 YP_003030459.1 CDS TBMG_00533 NC_012943.1 617025 617675 D thioredoxin 617025..617675 Mycobacterium tuberculosis KZN 1435 8164206 YP_003030460.1 CDS TBMG_00534 NC_012943.1 617672 618451 D cytochrome C biogenesis protein ccdA 617672..618451 Mycobacterium tuberculosis KZN 1435 8164207 YP_003030461.1 CDS TBMG_00535 NC_012943.1 618484 620073 D hypothetical protein 618484..620073 Mycobacterium tuberculosis KZN 1435 8164208 YP_003030462.1 CDS TBMG_00536 NC_012943.1 620070 621044 D cytochrome C biogenesis protein ccsA 620070..621044 Mycobacterium tuberculosis KZN 1435 8164209 YP_003030463.1 CDS TBMG_00537 NC_012943.1 621086 622303 D hypothetical protein 621086..622303 Mycobacterium tuberculosis KZN 1435 8164210 YP_003030464.1 CDS TBMG_00538 NC_012943.1 622508 622825 D hypothetical protein 622508..622825 Mycobacterium tuberculosis KZN 1435 8164211 YP_003030465.1 CDS TBMG_03988 NC_012943.1 622972 624840 D PE-PGRS family protein 622972..624840 Mycobacterium tuberculosis KZN 1435 8164212 YP_003030466.1 CDS TBMG_00539 NC_012943.1 624736 625743 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(624736..625743) Mycobacterium tuberculosis KZN 1435 8164213 YP_003030467.1 CDS TBMG_00540 NC_012943.1 625911 626702 R 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(625911..626702) Mycobacterium tuberculosis KZN 1435 8164214 YP_003030468.1 CDS TBMG_00541 NC_012943.1 626719 627513 D Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate; 5'-methylthioadenosine phosphorylase 626719..627513 Mycobacterium tuberculosis KZN 1435 8164215 YP_003030469.1 CDS TBMG_00542 NC_012943.1 627554 628549 D UDP-glucose 4-epimerase galE3 627554..628549 Mycobacterium tuberculosis KZN 1435 8164216 YP_003030470.1 CDS TBMG_00543 NC_012943.1 628559 629992 R hypothetical protein complement(628559..629992) Mycobacterium tuberculosis KZN 1435 8164217 YP_003030471.1 CDS TBMG_00544 NC_012943.1 630301 631947 D hypothetical protein 630301..631947 Mycobacterium tuberculosis KZN 1435 8164218 YP_003030472.1 CDS TBMG_00545 NC_012943.1 631980 632636 D dolichyl-phosphate sugar synthase 631980..632636 Mycobacterium tuberculosis KZN 1435 8164219 YP_003030473.1 CDS TBMG_00546 NC_012943.1 632633 633295 D hypothetical protein 632633..633295 Mycobacterium tuberculosis KZN 1435 8164220 YP_003030474.1 CDS TBMG_00547 NC_012943.1 633316 634665 R hypothetical protein complement(633316..634665) Mycobacterium tuberculosis KZN 1435 8164221 YP_003030475.1 CDS TBMG_00548 NC_012943.1 634677 635765 R O-succinylbenzoic acid--CoA ligase complement(634677..635765) Mycobacterium tuberculosis KZN 1435 8164222 YP_003030476.1 CDS TBMG_00549 NC_012943.1 635834 636136 R hypothetical protein complement(635834..636136) Mycobacterium tuberculosis KZN 1435 8164223 YP_003030477.1 CDS TBMG_00550 NC_012943.1 636196 636474 R hypothetical protein complement(636196..636474) Mycobacterium tuberculosis KZN 1435 8164224 YP_003030478.1 CDS TBMG_00551 NC_012943.1 636471 637724 R hypothetical protein complement(636471..637724) Mycobacterium tuberculosis KZN 1435 8164225 YP_003030479.1 CDS TBMG_00552 NC_012943.1 637844 638230 R hypothetical protein complement(637844..638230) Mycobacterium tuberculosis KZN 1435 8164226 YP_003030480.1 CDS TBMG_00553 NC_012943.1 638293 639177 R short chain dehydrogenase complement(638293..639177) Mycobacterium tuberculosis KZN 1435 8164227 YP_003030481.1 CDS TBMG_00554 NC_012943.1 639273 640217 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(639273..640217) Mycobacterium tuberculosis KZN 1435 8164228 YP_003030482.1 CDS TBMG_00555 NC_012943.1 640489 640902 R toxin complement(640489..640902) Mycobacterium tuberculosis KZN 1435 8164229 YP_003030483.1 CDS TBMG_03989 NC_012943.1 640899 641165 R antitoxin complement(640899..641165) Mycobacterium tuberculosis KZN 1435 8164230 YP_003030484.1 CDS TBMG_00556 NC_012943.1 641357 643072 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(641357..643072) Mycobacterium tuberculosis KZN 1435 8164231 YP_003030485.1 CDS TBMG_00557 NC_012943.1 643141 644754 D hypothetical protein 643141..644754 Mycobacterium tuberculosis KZN 1435 8164232 YP_003030486.1 CDS TBMG_00558 NC_012943.1 644751 645731 D catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 644751..645731 Mycobacterium tuberculosis KZN 1435 8164233 YP_003030487.1 CDS TBMG_00559 NC_012943.1 645728 646516 D peroxidase bpoC 645728..646516 Mycobacterium tuberculosis KZN 1435 8164234 YP_003030488.1 CDS TBMG_00560 NC_012943.1 646559 648223 D SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 646559..648223 Mycobacterium tuberculosis KZN 1435 8164235 YP_003030489.1 CDS TBMG_00561 NC_012943.1 648220 648735 D hypothetical protein 648220..648735 Mycobacterium tuberculosis KZN 1435 8164236 YP_003030490.1 CDS TBMG_00562 NC_012943.1 648797 649933 D mannosyltransferase 648797..649933 Mycobacterium tuberculosis KZN 1435 8164237 YP_003030491.1 CDS ubiE NC_012943.1 649950 650654 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 649950..650654 Mycobacterium tuberculosis KZN 1435 8164238 YP_003030492.1 CDS TBMG_00564 NC_012943.1 650668 651006 R hypothetical protein complement(650668..651006) Mycobacterium tuberculosis KZN 1435 8164239 YP_003030493.1 CDS TBMG_00565 NC_012943.1 651040 651765 R benzoquinone methyltransferase complement(651040..651765) Mycobacterium tuberculosis KZN 1435 8161970 YP_003030494.1 CDS TBMG_00566 NC_012943.1 651790 653016 R oxidoreductase complement(651790..653016) Mycobacterium tuberculosis KZN 1435 8161971 YP_003030495.1 CDS TBMG_00567 NC_012943.1 653032 654039 D polyprenyl synthetase 653032..654039 Mycobacterium tuberculosis KZN 1435 8161972 YP_003030496.1 CDS TBMG_00568 NC_012943.1 654140 655000 D metalloprotease; heat shock protein HtpX 654140..655000 Mycobacterium tuberculosis KZN 1435 8161973 YP_003030497.1 CDS TBMG_00569 NC_012943.1 655185 656270 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(655185..656270) Mycobacterium tuberculosis KZN 1435 8161974 YP_003030498.1 CDS TBMG_00570 NC_012943.1 656271 657731 R monooxygenase complement(656271..657731) Mycobacterium tuberculosis KZN 1435 8161975 YP_003030499.1 CDS TBMG_00571 NC_012943.1 657809 658300 R nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein complement(657809..658300) Mycobacterium tuberculosis KZN 1435 8161976 YP_003030500.1 CDS TBMG_00572 NC_012943.1 658579 659601 D methyltransferase/methylase 658579..659601 Mycobacterium tuberculosis KZN 1435 8161978 YP_003030501.1 CDS TBMG_00573 NC_012943.1 659711 661129 D cytochrome P450 135B1 cyp135B1 659711..661129 Mycobacterium tuberculosis KZN 1435 8161979 YP_003030502.1 CDS TBMG_00574 NC_012943.1 661195 661530 D hypothetical protein 661195..661530 Mycobacterium tuberculosis KZN 1435 8161980 YP_003030503.1 CDS TBMG_00575 NC_012943.1 661514 663634 D ribonucleoside-diphosphate reductase large subunit nrdZ 661514..663634 Mycobacterium tuberculosis KZN 1435 8161981 YP_003030504.1 CDS TBMG_00576 NC_012943.1 663748 665079 R hypothetical protein complement(663748..665079) Mycobacterium tuberculosis KZN 1435 8161982 YP_003030505.1 CDS TBMG_00577 NC_012943.1 665303 665644 R hypothetical protein complement(665303..665644) Mycobacterium tuberculosis KZN 1435 8161983 YP_003030506.1 CDS TBMG_03990 NC_012943.1 665695 665862 R hypothetical protein complement(665695..665862) Mycobacterium tuberculosis KZN 1435 8161984 YP_003030507.1 CDS TBMG_00578 NC_012943.1 666112 667503 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(666112..667503) Mycobacterium tuberculosis KZN 1435 8161985 YP_003030508.1 CDS TBMG_00579 NC_012943.1 667513 668655 R hypothetical protein complement(667513..668655) Mycobacterium tuberculosis KZN 1435 8161986 YP_003030509.1 CDS TBMG_00580 NC_012943.1 668840 670006 R hypothetical protein complement(668840..670006) Mycobacterium tuberculosis KZN 1435 8161987 YP_003030510.1 CDS TBMG_00581 NC_012943.1 670100 671413 D transcriptional regulator, arsR-family 670100..671413 Mycobacterium tuberculosis KZN 1435 8161988 YP_003030511.1 CDS TBMG_00582 NC_012943.1 671427 672212 D hypothetical protein 671427..672212 Mycobacterium tuberculosis KZN 1435 8161989 YP_003030512.1 CDS TBMG_03991 NC_012943.1 672257 676168 R PE-PGRS family protein complement(672257..676168) Mycobacterium tuberculosis KZN 1435 8161990 YP_003030513.1 CDS TBMG_00585 NC_012943.1 676284 676562 D hypothetical protein 676284..676562 Mycobacterium tuberculosis KZN 1435 8161991 YP_003030514.1 CDS TBMG_00586 NC_012943.1 676490 677248 D hypothetical protein 676490..677248 Mycobacterium tuberculosis KZN 1435 8161992 YP_003030515.1 CDS TBMG_00587 NC_012943.1 677377 677955 R hypothetical protein complement(677377..677955) Mycobacterium tuberculosis KZN 1435 8161993 YP_003030516.1 CDS TBMG_00588 NC_012943.1 677962 678177 D antitoxin 677962..678177 Mycobacterium tuberculosis KZN 1435 8161994 YP_003030517.1 CDS TBMG_00589 NC_012943.1 678174 678581 D toxin 678174..678581 Mycobacterium tuberculosis KZN 1435 8161995 YP_003030518.1 CDS TBMG_00590 NC_012943.1 678641 679327 R hypothetical protein complement(678641..679327) Mycobacterium tuberculosis KZN 1435 8161996 YP_003030519.1 CDS TBMG_00591 NC_012943.1 679481 682114 D hypothetical protein 679481..682114 Mycobacterium tuberculosis KZN 1435 8161997 YP_003030520.1 CDS TBMG_00592 NC_012943.1 682137 684524 R hypothetical protein complement(682137..684524) Mycobacterium tuberculosis KZN 1435 8161998 YP_003030521.1 CDS TBMG_00593 NC_012943.1 684662 685384 D GntR family transcriptional regulator 684662..685384 Mycobacterium tuberculosis KZN 1435 8161999 YP_003030522.1 CDS TBMG_00594 NC_012943.1 685381 686178 D hypothetical protein 685381..686178 Mycobacterium tuberculosis KZN 1435 8162000 YP_003030523.1 CDS TBMG_00595 NC_012943.1 686180 687067 D hypothetical protein 686180..687067 Mycobacterium tuberculosis KZN 1435 8162001 YP_003030524.1 CDS TBMG_00596 NC_012943.1 687073 688287 D MCE-family protein mce2A 687073..688287 Mycobacterium tuberculosis KZN 1435 8162002 YP_003030525.1 CDS TBMG_00597 NC_012943.1 688284 689111 D MCE-family protein mce2B 688284..689111 Mycobacterium tuberculosis KZN 1435 8162003 YP_003030526.1 CDS TBMG_00598 NC_012943.1 689060 689314 D MCE-family related protein 689060..689314 Mycobacterium tuberculosis KZN 1435 8162004 YP_003030527.1 CDS TBMG_00599 NC_012943.1 689311 690756 D MCE-family protein mce2C 689311..690756 Mycobacterium tuberculosis KZN 1435 8162005 YP_003030528.1 CDS TBMG_00600 NC_012943.1 690753 692279 D MCE-family protein mce2D 690753..692279 Mycobacterium tuberculosis KZN 1435 8162006 YP_003030529.1 CDS TBMG_00601 NC_012943.1 692276 693484 D MCE-family lipoprotein mce2E 692276..693484 Mycobacterium tuberculosis KZN 1435 8162007 YP_003030530.1 CDS TBMG_00602 NC_012943.1 693489 695039 D MCE-family protein mce2F 693489..695039 Mycobacterium tuberculosis KZN 1435 8162008 YP_003030531.1 CDS TBMG_00603 NC_012943.1 695091 695483 R toxin complement(695091..695483) Mycobacterium tuberculosis KZN 1435 8162009 YP_003030532.1 CDS TBMG_00604 NC_012943.1 695480 695737 R antitoxin complement(695480..695737) Mycobacterium tuberculosis KZN 1435 8162010 YP_003030533.1 CDS TBMG_00605 NC_012943.1 695920 697155 R hypothetical protein complement(695920..697155) Mycobacterium tuberculosis KZN 1435 8162011 YP_003030534.1 CDS TBMG_00606 NC_012943.1 697406 697819 R toxin complement(697406..697819) Mycobacterium tuberculosis KZN 1435 8162012 YP_003030535.1 CDS TBMG_00607 NC_012943.1 697816 698052 R antitoxin complement(697816..698052) Mycobacterium tuberculosis KZN 1435 8162013 YP_003030536.1 CDS TBMG_00608 NC_012943.1 698156 699289 R two component system sensor kinase complement(698156..699289) Mycobacterium tuberculosis KZN 1435 8162014 YP_003030537.1 CDS TBMG_00609 NC_012943.1 699290 700051 R two component system transcriptional regulator tcrA complement(699290..700051) Mycobacterium tuberculosis KZN 1435 8162015 YP_003030538.1 CDS TBMG_00610 NC_012943.1 700108 700419 D hypothetical protein 700108..700419 Mycobacterium tuberculosis KZN 1435 8162016 YP_003030539.1 CDS TBMG_00611 NC_012943.1 700515 701441 D hypothetical protein 700515..701441 Mycobacterium tuberculosis KZN 1435 8162017 YP_003030540.1 CDS TBMG_00612 NC_012943.1 701658 702266 D resolvase 701658..702266 Mycobacterium tuberculosis KZN 1435 8162018 YP_003030541.1 CDS TBMG_00613 NC_012943.1 702268 703011 D transposase 702268..703011 Mycobacterium tuberculosis KZN 1435 8162019 YP_003030542.1 CDS TBMG_00614 NC_012943.1 702981 703451 D hypothetical protein 702981..703451 Mycobacterium tuberculosis KZN 1435 8162020 YP_003030543.1 CDS TBMG_00615 NC_012943.1 703496 703741 D antitoxin 703496..703741 Mycobacterium tuberculosis KZN 1435 8162021 YP_003030544.1 CDS TBMG_03992 NC_012943.1 703738 704139 D toxin 703738..704139 Mycobacterium tuberculosis KZN 1435 8162022 YP_003030545.1 CDS TBMG_03993 NC_012943.1 704082 704309 D hypothetical protein 704082..704309 Mycobacterium tuberculosis KZN 1435 8162023 YP_003030546.1 CDS TBMG_03994 NC_012943.1 704237 704464 D hypothetical protein 704237..704464 Mycobacterium tuberculosis KZN 1435 8162024 YP_003030547.1 CDS TBMG_00617 NC_012943.1 704676 705011 D hypothetical protein 704676..705011 Mycobacterium tuberculosis KZN 1435 8162025 YP_003030548.1 CDS TBMG_00618 NC_012943.1 705004 706161 R hypothetical protein complement(705004..706161) Mycobacterium tuberculosis KZN 1435 8162026 YP_003030549.1 CDS TBMG_00619 NC_012943.1 706213 706596 R hypothetical protein complement(706213..706596) Mycobacterium tuberculosis KZN 1435 8162027 YP_003030550.1 CDS TBMG_00620 NC_012943.1 706576 707181 D hypothetical protein 706576..707181 Mycobacterium tuberculosis KZN 1435 8162029 YP_003030551.1 CDS TBMG_00621 NC_012943.1 707200 709767 R hypothetical protein complement(707200..709767) Mycobacterium tuberculosis KZN 1435 8162028 YP_003030552.1 CDS TBMG_00622 NC_012943.1 709707 710600 D hypothetical protein 709707..710600 Mycobacterium tuberculosis KZN 1435 8162031 YP_003030553.1 CDS TBMG_00623 NC_012943.1 710597 710839 D hypothetical protein 710597..710839 Mycobacterium tuberculosis KZN 1435 8162030 YP_003030554.1 CDS TBMG_00624 NC_012943.1 710836 711102 R hypothetical protein complement(710836..711102) Mycobacterium tuberculosis KZN 1435 8162032 YP_003030555.1 CDS TBMG_00625 NC_012943.1 711034 711261 D antitoxin 711034..711261 Mycobacterium tuberculosis KZN 1435 8162034 YP_003030556.1 CDS TBMG_00626 NC_012943.1 711258 711659 D toxin 711258..711659 Mycobacterium tuberculosis KZN 1435 8162033 YP_003030557.1 CDS TBMG_00627 NC_012943.1 711788 712483 D galactose-1-phosphate uridylyltransferase galTa 711788..712483 Mycobacterium tuberculosis KZN 1435 8162035 YP_003030558.1 CDS TBMG_00628 NC_012943.1 712501 712971 D galactose-1-phosphate uridylyltransferase galTb 712501..712971 Mycobacterium tuberculosis KZN 1435 8162036 YP_003030559.1 CDS TBMG_00629 NC_012943.1 712968 714059 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 712968..714059 Mycobacterium tuberculosis KZN 1435 8162037 YP_003030560.1 CDS TBMG_00630 NC_012943.1 714445 715518 D hypothetical protein 714445..715518 Mycobacterium tuberculosis KZN 1435 8162038 YP_003030561.1 CDS TBMG_00631 NC_012943.1 715544 716569 D hypothetical protein 715544..716569 Mycobacterium tuberculosis KZN 1435 8162039 YP_003030562.1 CDS TBMG_00632 NC_012943.1 716662 716916 D antitoxin 716662..716916 Mycobacterium tuberculosis KZN 1435 8162040 YP_003030563.1 CDS TBMG_00633 NC_012943.1 716916 717311 D toxin 716916..717311 Mycobacterium tuberculosis KZN 1435 8162041 YP_003030564.1 CDS TBMG_00634 NC_012943.1 717405 718145 R hypothetical protein complement(717405..718145) Mycobacterium tuberculosis KZN 1435 8162042 YP_003030565.1 CDS TBMG_00635 NC_012943.1 718277 718537 D antitoxin 718277..718537 Mycobacterium tuberculosis KZN 1435 8162043 YP_003030566.1 CDS TBMG_00636 NC_012943.1 718534 718941 D toxin 718534..718941 Mycobacterium tuberculosis KZN 1435 8162044 YP_003030567.1 CDS TBMG_00637 NC_012943.1 719013 720164 R hypothetical protein complement(719013..720164) Mycobacterium tuberculosis KZN 1435 8162045 YP_003030568.1 CDS TBMG_00638 NC_012943.1 720257 721984 R exonuclease subunit V alpha recD complement(720257..721984) Mycobacterium tuberculosis KZN 1435 8162046 YP_003030569.1 CDS TBMG_00639 NC_012943.1 721981 725265 R exonuclease subunit V beta recB complement(721981..725265) Mycobacterium tuberculosis KZN 1435 8162047 YP_003030570.1 CDS TBMG_00640 NC_012943.1 725265 728558 R exonuclease subunit V gamma recC complement(725265..728558) Mycobacterium tuberculosis KZN 1435 8162048 YP_003030571.1 CDS TBMG_00641 NC_012943.1 728835 729530 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(728835..729530) Mycobacterium tuberculosis KZN 1435 8162049 YP_003030572.1 CDS TBMG_00642 NC_012943.1 729579 730439 R hypothetical protein complement(729579..730439) Mycobacterium tuberculosis KZN 1435 8162050 YP_003030573.1 CDS TBMG_00643 NC_012943.1 730572 731285 R glyoxalase II complement(730572..731285) Mycobacterium tuberculosis KZN 1435 8164240 YP_003030574.1 CDS TBMG_00644 NC_012943.1 731365 731616 D hypothetical protein 731365..731616 Mycobacterium tuberculosis KZN 1435 8163290 YP_003030575.1 CDS rpmG NC_012943.1 731964 732131 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 731964..732131 Mycobacterium tuberculosis KZN 1435 8163293 YP_003030576.1 CDS TBMG_00646 NC_012943.1 732182 732658 D functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadA 732182..732658 Mycobacterium tuberculosis KZN 1435 8163294 YP_003030577.1 CDS TBMG_00647 NC_012943.1 732576 733073 D functions as a heterodimer along with HadA or HadC in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadB 732576..733073 Mycobacterium tuberculosis KZN 1435 8163295 YP_003030578.1 CDS TBMG_00648 NC_012943.1 733077 733577 D functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadC 733077..733577 Mycobacterium tuberculosis KZN 1435 8163296 YP_003030579.1 CDS secE NC_012943.1 733989 734474 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 733989..734474 Mycobacterium tuberculosis KZN 1435 8163298 YP_003030580.1 CDS nusG NC_012943.1 734506 735222 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 734506..735222 Mycobacterium tuberculosis KZN 1435 8163299 YP_003030581.1 CDS rplK NC_012943.1 735274 735702 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 735274..735702 Mycobacterium tuberculosis KZN 1435 8163300 YP_003030582.1 CDS rplA NC_012943.1 735769 736476 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 735769..736476 Mycobacterium tuberculosis KZN 1435 8163301 YP_003030583.1 CDS TBMG_00653 NC_012943.1 736550 737497 R methoxy mycolic acid synthase 4 mmaA4 complement(736550..737497) Mycobacterium tuberculosis KZN 1435 8163302 YP_003030584.1 CDS TBMG_00654 NC_012943.1 737520 738413 R methoxy mycolic acid synthase 3 mmaA3 complement(737520..738413) Mycobacterium tuberculosis KZN 1435 8163303 YP_003030585.1 CDS TBMG_00655 NC_012943.1 738549 739502 R methoxy mycolic acid synthase 2 mmaA2 complement(738549..739502) Mycobacterium tuberculosis KZN 1435 8163304 YP_003030586.1 CDS TBMG_00656 NC_012943.1 739579 740469 R methoxy mycolic acid synthase 1 mmaA1 complement(739579..740469) Mycobacterium tuberculosis KZN 1435 8163305 YP_003030587.1 CDS TBMG_00657 NC_012943.1 740486 741391 R lipase/esterase complement(740486..741391) Mycobacterium tuberculosis KZN 1435 8163306 YP_003030588.1 CDS TBMG_00658 NC_012943.1 741403 742869 R hypothetical protein complement(741403..742869) Mycobacterium tuberculosis KZN 1435 8163307 YP_003030589.1 CDS TBMG_00659 NC_012943.1 742955 747151 D alpha-mannosidase 742955..747151 Mycobacterium tuberculosis KZN 1435 8163308 YP_003030590.1 CDS TBMG_00660 NC_012943.1 747148 747822 D malonyl CoA-acyl carrier protein transacylase fabD2 747148..747822 Mycobacterium tuberculosis KZN 1435 8163309 YP_003030591.1 CDS TBMG_00661 NC_012943.1 747822 748730 D sugar kinase 747822..748730 Mycobacterium tuberculosis KZN 1435 8163310 YP_003030592.1 CDS rplJ NC_012943.1 749061 749597 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 749061..749597 Mycobacterium tuberculosis KZN 1435 8163311 YP_003030593.1 CDS rplL NC_012943.1 749634 750026 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 749634..750026 Mycobacterium tuberculosis KZN 1435 8163312 YP_003030594.1 CDS TBMG_00664 NC_012943.1 750019 750786 R TetR family transcriptional regulator complement(750019..750786) Mycobacterium tuberculosis KZN 1435 8163313 YP_003030595.1 CDS TBMG_00665 NC_012943.1 750785 752290 D dioxygenase 750785..752290 Mycobacterium tuberculosis KZN 1435 8163315 YP_003030596.1 CDS TBMG_00666 NC_012943.1 752302 753381 D ribonucleotide-transport ATP-binding protein ABC transporter mkl 752302..753381 Mycobacterium tuberculosis KZN 1435 8163314 YP_003030597.1 CDS TBMG_00667 NC_012943.1 753769 754152 R toxin complement(753769..754152) Mycobacterium tuberculosis KZN 1435 8163316 YP_003030598.1 CDS TBMG_00668 NC_012943.1 754247 754402 R antitoxin complement(754247..754402) Mycobacterium tuberculosis KZN 1435 8163317 YP_003030599.1 CDS TBMG_00669 NC_012943.1 754478 755194 R hypothetical protein complement(754478..755194) Mycobacterium tuberculosis KZN 1435 8163318 YP_003030600.1 CDS TBMG_00670 NC_012943.1 755470 755778 R toxin complement(755470..755778) Mycobacterium tuberculosis KZN 1435 8163319 YP_003030601.1 CDS TBMG_00671 NC_012943.1 755765 756010 R antitoxin complement(755765..756010) Mycobacterium tuberculosis KZN 1435 8163320 YP_003030602.1 CDS TBMG_00672 NC_012943.1 756120 756557 R toxin complement(756120..756557) Mycobacterium tuberculosis KZN 1435 8163321 YP_003030603.1 CDS TBMG_00673 NC_012943.1 756554 756922 R antitoxin complement(756554..756922) Mycobacterium tuberculosis KZN 1435 8163322 YP_003030604.1 CDS TBMG_00674 NC_012943.1 756922 759285 D arylsulfatase 756922..759285 Mycobacterium tuberculosis KZN 1435 8163323 YP_003030605.1 CDS TBMG_00675 NC_012943.1 759317 759589 D antitoxin 759317..759589 Mycobacterium tuberculosis KZN 1435 8163324 YP_003030606.1 CDS TBMG_00676 NC_012943.1 759586 759924 D toxin 759586..759924 Mycobacterium tuberculosis KZN 1435 8163325 YP_003030607.1 CDS TBMG_00677 NC_012943.1 759921 760094 D hypothetical protein 759921..760094 Mycobacterium tuberculosis KZN 1435 8163326 YP_003030608.1 CDS TBMG_00678 NC_012943.1 760079 760309 D hypothetical protein 760079..760309 Mycobacterium tuberculosis KZN 1435 8163327 YP_003030609.1 CDS rpoB NC_012943.1 760574 764110 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 760574..764110 Mycobacterium tuberculosis KZN 1435 8163328 YP_003030610.1 CDS TBMG_00680 NC_012943.1 764155 768105 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 764155..768105 Mycobacterium tuberculosis KZN 1435 8163329 YP_003030611.1 CDS TBMG_00681 NC_012943.1 768102 768422 R hypothetical protein complement(768102..768422) Mycobacterium tuberculosis KZN 1435 8163330 YP_003030612.1 CDS TBMG_00682 NC_012943.1 768469 770382 R hydrolase complement(768469..770382) Mycobacterium tuberculosis KZN 1435 8163331 YP_003030613.1 CDS TBMG_00683 NC_012943.1 770675 771334 D truncated CDS; endonuclease IV end 770675..771334 Mycobacterium tuberculosis KZN 1435 8163332 YP_003030614.1 CDS TBMG_00684 NC_012943.1 771366 772208 D hypothetical protein 771366..772208 Mycobacterium tuberculosis KZN 1435 8163333 YP_003030615.1 CDS TBMG_00685 NC_012943.1 772268 773896 D acyl-CoA dehydrogenase 772268..773896 Mycobacterium tuberculosis KZN 1435 8163334 YP_003030616.1 CDS TBMG_00686 NC_012943.1 773907 774845 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 773907..774845 Mycobacterium tuberculosis KZN 1435 8163335 YP_003030617.1 CDS TBMG_00687 NC_012943.1 774848 775570 D hypothetical protein 774848..775570 Mycobacterium tuberculosis KZN 1435 8163336 YP_003030618.1 CDS TBMG_00688 NC_012943.1 775567 776358 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 775567..776358 Mycobacterium tuberculosis KZN 1435 8163337 YP_003030619.1 CDS TBMG_00689 NC_012943.1 776370 779264 R transmembrane transporter mmpL5 complement(776370..779264) Mycobacterium tuberculosis KZN 1435 8163338 YP_003030620.1 CDS TBMG_00690 NC_012943.1 779261 779689 R hypothetical protein complement(779261..779689) Mycobacterium tuberculosis KZN 1435 8163339 YP_003030621.1 CDS TBMG_00691 NC_012943.1 779774 780271 D hypothetical protein 779774..780271 Mycobacterium tuberculosis KZN 1435 8163340 YP_003030622.1 CDS TBMG_00692 NC_012943.1 780327 780824 R hypothetical protein complement(780327..780824) Mycobacterium tuberculosis KZN 1435 8163341 YP_003030623.1 CDS TBMG_00693 NC_012943.1 780826 781200 R hypothetical protein complement(780826..781200) Mycobacterium tuberculosis KZN 1435 8163342 YP_003030624.1 CDS TBMG_00694 NC_012943.1 781439 782095 D TetR family transcriptional regulator 781439..782095 Mycobacterium tuberculosis KZN 1435 8163343 YP_003030625.1 CDS rpsL NC_012943.1 782344 782718 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 782344..782718 Mycobacterium tuberculosis KZN 1435 8163344 YP_003030626.1 CDS TBMG_00696 NC_012943.1 782718 783188 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 782718..783188 Mycobacterium tuberculosis KZN 1435 8163345 YP_003030627.1 CDS TBMG_00697 NC_012943.1 783269 785374 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 783269..785374 Mycobacterium tuberculosis KZN 1435 8163346 YP_003030628.1 CDS TBMG_00698 NC_012943.1 785605 786795 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 785605..786795 Mycobacterium tuberculosis KZN 1435 8163347 YP_003030629.1 CDS TBMG_00699 NC_012943.1 786933 787730 D hypothetical protein 786933..787730 Mycobacterium tuberculosis KZN 1435 8163348 YP_003030630.1 CDS fabG NC_012943.1 787883 788710 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 787883..788710 Mycobacterium tuberculosis KZN 1435 8163349 YP_003030631.1 CDS TBMG_00701 NC_012943.1 788724 789944 D ferredoxin reductase 788724..789944 Mycobacterium tuberculosis KZN 1435 8163350 YP_003030632.1 CDS TBMG_00702 NC_012943.1 789941 790195 R hypothetical protein complement(789941..790195) Mycobacterium tuberculosis KZN 1435 8163351 YP_003030633.1 CDS TBMG_00703 NC_012943.1 790808 791857 R hypothetical protein complement(790808..791857) Mycobacterium tuberculosis KZN 1435 8163352 YP_003030634.1 CDS TBMG_00704 NC_012943.1 791854 792450 R transcriptional regulator complement(791854..792450) Mycobacterium tuberculosis KZN 1435 8163353 YP_003030635.1 CDS TBMG_00705 NC_012943.1 792615 792944 D hypothetical protein 792615..792944 Mycobacterium tuberculosis KZN 1435 8163354 YP_003030636.1 CDS TBMG_00706 NC_012943.1 792941 794116 D coenzyme pqq synthesis protein E pqqE 792941..794116 Mycobacterium tuberculosis KZN 1435 8163355 YP_003030637.1 CDS TBMG_00707 NC_012943.1 794119 795309 D L-lactate dehydrogenase lldD1 794119..795309 Mycobacterium tuberculosis KZN 1435 8163356 YP_003030638.1 CDS TBMG_00708 NC_012943.1 795499 796254 D hypothetical protein 795499..796254 Mycobacterium tuberculosis KZN 1435 8163357 YP_003030639.1 CDS TBMG_00709 NC_012943.1 796303 797715 D membrane sugar transferase 796303..797715 Mycobacterium tuberculosis KZN 1435 8163358 YP_003030640.1 CDS TBMG_00710 NC_012943.1 797717 799156 D dehydrogenase 797717..799156 Mycobacterium tuberculosis KZN 1435 8163359 YP_003030641.1 CDS TBMG_03995 NC_012943.1 799617 800228 D hypothetical protein 799617..800228 Mycobacterium tuberculosis KZN 1435 8163360 YP_003030642.1 CDS TBMG_00711 NC_012943.1 799944 800591 R hypothetical protein complement(799944..800591) Mycobacterium tuberculosis KZN 1435 8163361 YP_003030643.1 CDS TBMG_00712 NC_012943.1 800888 801178 R hypothetical protein complement(800888..801178) Mycobacterium tuberculosis KZN 1435 8163362 YP_003030644.1 CDS rpsJ NC_012943.1 801271 801576 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 801271..801576 Mycobacterium tuberculosis KZN 1435 8163363 YP_003030645.1 CDS rplC NC_012943.1 801593 802246 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 801593..802246 Mycobacterium tuberculosis KZN 1435 8163364 YP_003030646.1 CDS rplD NC_012943.1 802246 802917 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 802246..802917 Mycobacterium tuberculosis KZN 1435 8163365 YP_003030647.1 CDS rplW NC_012943.1 802917 803219 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 802917..803219 Mycobacterium tuberculosis KZN 1435 8163366 YP_003030648.1 CDS rplB NC_012943.1 803528 804370 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 803528..804370 Mycobacterium tuberculosis KZN 1435 8163367 YP_003030649.1 CDS rpsS NC_012943.1 804411 804692 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 804411..804692 Mycobacterium tuberculosis KZN 1435 8163368 YP_003030650.1 CDS rplV NC_012943.1 804689 805282 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 804689..805282 Mycobacterium tuberculosis KZN 1435 8163369 YP_003030651.1 CDS rpsC NC_012943.1 805282 806106 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 805282..806106 Mycobacterium tuberculosis KZN 1435 8163370 YP_003030652.1 CDS rplP NC_012943.1 806110 806526 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 806110..806526 Mycobacterium tuberculosis KZN 1435 8163371 YP_003030653.1 CDS TBMG_00723 NC_012943.1 806526 806759 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 806526..806759 Mycobacterium tuberculosis KZN 1435 8163372 YP_003030654.1 CDS rpsQ NC_012943.1 806798 807166 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 806798..807166 Mycobacterium tuberculosis KZN 1435 8163373 YP_003030655.1 CDS TBMG_00725 NC_012943.1 807335 809698 D arylsulfatase 807335..809698 Mycobacterium tuberculosis KZN 1435 8163374 YP_003030656.1 CDS TBMG_00726 NC_012943.1 809746 810645 D hypothetical protein 809746..810645 Mycobacterium tuberculosis KZN 1435 8163375 YP_003030657.1 CDS TBMG_00727 NC_012943.1 810946 811887 D hypothetical protein 810946..811887 Mycobacterium tuberculosis KZN 1435 8163376 YP_003030658.1 CDS rplN NC_012943.1 812373 812741 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 812373..812741 Mycobacterium tuberculosis KZN 1435 8162905 YP_003030659.1 CDS rplX NC_012943.1 812742 813059 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 812742..813059 Mycobacterium tuberculosis KZN 1435 8162906 YP_003030660.1 CDS rplE NC_012943.1 813059 813622 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 813059..813622 Mycobacterium tuberculosis KZN 1435 8162907 YP_003030661.1 CDS rpsN NC_012943.1 813627 813809 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 813627..813809 Mycobacterium tuberculosis KZN 1435 8162908 YP_003030662.1 CDS rpsH NC_012943.1 813976 814374 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 813976..814374 Mycobacterium tuberculosis KZN 1435 8162909 YP_003030663.1 CDS rplF NC_012943.1 814398 814937 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 814398..814937 Mycobacterium tuberculosis KZN 1435 8162910 YP_003030664.1 CDS rplR NC_012943.1 814940 815308 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 814940..815308 Mycobacterium tuberculosis KZN 1435 8162911 YP_003030665.1 CDS rpsE NC_012943.1 815328 815990 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 815328..815990 Mycobacterium tuberculosis KZN 1435 8162912 YP_003030666.1 CDS rpmD NC_012943.1 815993 816190 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 815993..816190 Mycobacterium tuberculosis KZN 1435 8162913 YP_003030667.1 CDS rplO NC_012943.1 816190 816630 D late assembly protein; 50S ribosomal protein L15 816190..816630 Mycobacterium tuberculosis KZN 1435 8162914 YP_003030668.1 CDS TBMG_00738 NC_012943.1 816663 818534 D protease IV sppA 816663..818534 Mycobacterium tuberculosis KZN 1435 8162915 YP_003030669.1 CDS TBMG_03996 NC_012943.1 818531 818905 R hypothetical protein complement(818531..818905) Mycobacterium tuberculosis KZN 1435 8162916 YP_003030670.1 CDS TBMG_03997 NC_012943.1 818539 819444 R hypothetical protein complement(818539..819444) Mycobacterium tuberculosis KZN 1435 8162917 YP_003030671.1 CDS TBMG_00740 NC_012943.1 819537 820640 R hypothetical protein complement(819537..820640) Mycobacterium tuberculosis KZN 1435 8162918 YP_003030672.1 CDS TBMG_00741 NC_012943.1 820843 821499 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose-phosphate aldolase complement(820843..821499) Mycobacterium tuberculosis KZN 1435 8162919 YP_003030673.1 CDS TBMG_00742 NC_012943.1 821496 822476 R D-3-phosphoglycerate dehydrogenase serA2 complement(821496..822476) Mycobacterium tuberculosis KZN 1435 8162920 YP_003030674.1 CDS TBMG_00743 NC_012943.1 822507 823853 D D-xylulose kinase xylB 822507..823853 Mycobacterium tuberculosis KZN 1435 8162921 YP_003030675.1 CDS TBMG_00744 NC_012943.1 823866 824594 D hypothetical protein 823866..824594 Mycobacterium tuberculosis KZN 1435 8162922 YP_003030676.1 CDS TBMG_00745 NC_012943.1 824683 825639 R hypothetical protein complement(824683..825639) Mycobacterium tuberculosis KZN 1435 8162923 YP_003030677.1 CDS secY NC_012943.1 825800 827125 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 825800..827125 Mycobacterium tuberculosis KZN 1435 8162924 YP_003030678.1 CDS adk NC_012943.1 827122 827667 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 827122..827667 Mycobacterium tuberculosis KZN 1435 8162925 YP_003030679.1 CDS TBMG_00748 NC_012943.1 827670 828470 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 827670..828470 Mycobacterium tuberculosis KZN 1435 8162926 YP_003030680.1 CDS TBMG_00749 NC_012943.1 828543 829076 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and secreted or membrane proteins; RNA polymerase sigma factor SigL 828543..829076 Mycobacterium tuberculosis KZN 1435 8162927 YP_003030681.1 CDS TBMG_00750 NC_012943.1 829140 829892 D hypothetical protein 829140..829892 Mycobacterium tuberculosis KZN 1435 8162928 YP_003030682.1 CDS TBMG_00751 NC_012943.1 830207 830704 D transcriptional regulator 830207..830704 Mycobacterium tuberculosis KZN 1435 8162929 YP_003030683.1 CDS TBMG_00752 NC_012943.1 831062 831610 D hypothetical protein 831062..831610 Mycobacterium tuberculosis KZN 1435 8162930 YP_003030684.1 CDS TBMG_00753 NC_012943.1 831855 832661 D hypothetical protein 831855..832661 Mycobacterium tuberculosis KZN 1435 8162931 YP_003030685.1 CDS TBMG_00754 NC_012943.1 832695 833303 D hypothetical protein 832695..833303 Mycobacterium tuberculosis KZN 1435 8162932 YP_003030686.1 CDS TBMG_00755 NC_012943.1 833534 833848 D transposase 833534..833848 Mycobacterium tuberculosis KZN 1435 8162933 YP_003030687.1 CDS TBMG_00756 NC_012943.1 833990 834508 D PE-PGRS family protein 833990..834508 Mycobacterium tuberculosis KZN 1435 8162934 YP_003030688.1 CDS TBMG_00757 NC_012943.1 834886 835443 R hypothetical protein complement(834886..835443) Mycobacterium tuberculosis KZN 1435 8162935 YP_003030689.1 CDS TBMG_00758 NC_012943.1 835440 835946 R transcriptional regulator complement(835440..835946) Mycobacterium tuberculosis KZN 1435 8162936 YP_003030690.1 CDS TBMG_03998 NC_012943.1 836059 836205 R 3-hydroxyisobutyrate dehydrogenase complement(836059..836205) Mycobacterium tuberculosis KZN 1435 8162937 YP_003030691.1 CDS TBMG_00759 NC_012943.1 836154 836681 D hypothetical protein 836154..836681 Mycobacterium tuberculosis KZN 1435 8162939 YP_003030692.1 CDS TBMG_00760 NC_012943.1 836701 839052 D PE-PGRS family protein 836701..839052 Mycobacterium tuberculosis KZN 1435 8162938 YP_003030693.1 CDS TBMG_00761 NC_012943.1 839451 842054 D hypothetical protein 839451..842054 Mycobacterium tuberculosis KZN 1435 8162940 YP_003030694.1 CDS TBMG_00762 NC_012943.1 842145 842402 D antitoxin 842145..842402 Mycobacterium tuberculosis KZN 1435 8162941 YP_003030695.1 CDS TBMG_00763 NC_012943.1 842426 842854 D toxin 842426..842854 Mycobacterium tuberculosis KZN 1435 8162942 YP_003030696.1 CDS TBMG_00764 NC_012943.1 843207 843476 D hypothetical protein 843207..843476 Mycobacterium tuberculosis KZN 1435 8162943 YP_003030697.1 CDS TBMG_00765 NC_012943.1 843545 844429 R 3-hydroxyisobutyrate dehydrogenase complement(843545..844429) Mycobacterium tuberculosis KZN 1435 8162944 YP_003030698.1 CDS TBMG_00766 NC_012943.1 844440 845612 R acyl-CoA dehydrogenase complement(844440..845612) Mycobacterium tuberculosis KZN 1435 8162945 YP_003030699.1 CDS TBMG_00767 NC_012943.1 845619 847151 R methylmalonate-semialdehyde dehydrogenase mmsA complement(845619..847151) Mycobacterium tuberculosis KZN 1435 8162946 YP_003030700.1 CDS TBMG_00768 NC_012943.1 847357 849111 D PE-PGRS family protein 847357..849111 Mycobacterium tuberculosis KZN 1435 8162947 YP_003030701.1 CDS TBMG_00769 NC_012943.1 849301 851241 R PPE family protein complement(849301..851241) Mycobacterium tuberculosis KZN 1435 8162948 YP_003030702.1 CDS TBMG_00770 NC_012943.1 851540 851725 R transposase complement(851540..851725) Mycobacterium tuberculosis KZN 1435 8162949 YP_003030703.1 CDS TBMG_00771 NC_012943.1 851939 852664 R hypothetical protein complement(851939..852664) Mycobacterium tuberculosis KZN 1435 8162951 YP_003030704.1 CDS TBMG_00772 NC_012943.1 852806 853549 D two component system transcriptional regulator phoP 852806..853549 Mycobacterium tuberculosis KZN 1435 8162952 YP_003030705.1 CDS TBMG_00773 NC_012943.1 853594 855051 D two component system sensor kinase phoR 853594..855051 Mycobacterium tuberculosis KZN 1435 8162953 YP_003030706.1 CDS TBMG_00774 NC_012943.1 855023 855424 R hypothetical protein complement(855023..855424) Mycobacterium tuberculosis KZN 1435 8162954 YP_003030707.1 CDS TBMG_00775 NC_012943.1 855464 855883 R hypothetical protein complement(855464..855883) Mycobacterium tuberculosis KZN 1435 8162955 YP_003030708.1 CDS TBMG_00776 NC_012943.1 855896 857023 R zinc-type alcohol dehydrogenase NAD dependent adhB complement(855896..857023) Mycobacterium tuberculosis KZN 1435 8162956 YP_003030709.1 CDS TBMG_00777 NC_012943.1 857122 857667 R hypothetical protein complement(857122..857667) Mycobacterium tuberculosis KZN 1435 8162957 YP_003030710.1 CDS TBMG_00778 NC_012943.1 857670 857876 R ferredoxin complement(857670..857876) Mycobacterium tuberculosis KZN 1435 8162958 YP_003030711.1 CDS TBMG_00779 NC_012943.1 857879 859234 R cytochrome P450 51 cyp51 complement(857879..859234) Mycobacterium tuberculosis KZN 1435 8162959 YP_003030712.1 CDS TBMG_00780 NC_012943.1 859234 860061 R short chain dehydrogenase complement(859234..860061) Mycobacterium tuberculosis KZN 1435 8162960 YP_003030713.1 CDS TBMG_00781 NC_012943.1 860311 861270 R truncated CDS; cytochrome P450 123 cyp123 complement(860311..861270) Mycobacterium tuberculosis KZN 1435 8162961 YP_003030714.1 CDS TBMG_00782 NC_012943.1 861295 861909 R hypothetical protein complement(861295..861909) Mycobacterium tuberculosis KZN 1435 8162962 YP_003030715.1 CDS TBMG_00783 NC_012943.1 862111 863580 D aldehyde dehydrogenase 862111..863580 Mycobacterium tuberculosis KZN 1435 8162963 YP_003030716.1 CDS TBMG_00784 NC_012943.1 863611 864357 D short chain dehydrogenase 863611..864357 Mycobacterium tuberculosis KZN 1435 8162964 YP_003030717.1 CDS TBMG_00785 NC_012943.1 864455 865342 D dehydrogenase/reductase 864455..865342 Mycobacterium tuberculosis KZN 1435 8162965 YP_003030718.1 CDS TBMG_00786 NC_012943.1 865339 865773 D 4-carboxymuconolactone decarboxylase 865339..865773 Mycobacterium tuberculosis KZN 1435 8162966 YP_003030719.1 CDS TBMG_00787 NC_012943.1 865785 867053 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 865785..867053 Mycobacterium tuberculosis KZN 1435 8162967 YP_003030720.1 CDS TBMG_00788 NC_012943.1 867050 868588 R bifunctional acylase ggtA complement(867050..868588) Mycobacterium tuberculosis KZN 1435 8162968 YP_003030721.1 CDS TBMG_00789 NC_012943.1 868639 869550 R hypothetical protein complement(868639..869550) Mycobacterium tuberculosis KZN 1435 8162969 YP_003030722.1 CDS TBMG_00790 NC_012943.1 869606 870229 D hypothetical protein 869606..870229 Mycobacterium tuberculosis KZN 1435 8162970 YP_003030723.1 CDS TBMG_00791 NC_012943.1 870183 870962 R hypothetical protein complement(870183..870962) Mycobacterium tuberculosis KZN 1435 8162971 YP_003030724.1 CDS TBMG_00792 NC_012943.1 871207 872625 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 871207..872625 Mycobacterium tuberculosis KZN 1435 8162972 YP_003030725.1 CDS TBMG_00793 NC_012943.1 872630 873874 D cytochrome P450 126 cyp126 872630..873874 Mycobacterium tuberculosis KZN 1435 8162973 YP_003030726.1 CDS TBMG_00794 NC_012943.1 873871 874554 R hypothetical protein complement(873871..874554) Mycobacterium tuberculosis KZN 1435 8162974 YP_003030727.1 CDS TBMG_00795 NC_012943.1 874542 875435 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 874542..875435 Mycobacterium tuberculosis KZN 1435 8162976 YP_003030728.1 CDS TBMG_00796 NC_012943.1 875435 877591 D protease II ptrB 875435..877591 Mycobacterium tuberculosis KZN 1435 8162975 YP_003030729.1 CDS TBMG_00797 NC_012943.1 877520 877912 R hypothetical protein complement(877520..877912) Mycobacterium tuberculosis KZN 1435 8162977 YP_003030730.1 CDS TBMG_03999 NC_012943.1 877890 878030 D transcriptional regulator 877890..878030 Mycobacterium tuberculosis KZN 1435 8162979 YP_003030731.1 CDS TBMG_00798 NC_012943.1 878019 879656 R multidrug resistance membrane efflux protein emrB complement(878019..879656) Mycobacterium tuberculosis KZN 1435 8162978 YP_003030732.1 CDS TBMG_00799 NC_012943.1 879821 880525 D hypothetical protein 879821..880525 Mycobacterium tuberculosis KZN 1435 8162980 YP_003030733.1 CDS TBMG_00800 NC_012943.1 880541 882241 D proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 880541..882241 Mycobacterium tuberculosis KZN 1435 8162981 YP_003030734.1 CDS TBMG_00801 NC_012943.1 882276 882914 R hypothetical protein complement(882276..882914) Mycobacterium tuberculosis KZN 1435 8162982 YP_003030735.1 CDS TBMG_00802 NC_012943.1 882660 883619 D hypothetical protein 882660..883619 Mycobacterium tuberculosis KZN 1435 8162984 YP_003030736.1 CDS TBMG_00803 NC_012943.1 883725 883964 D With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS 883725..883964 Mycobacterium tuberculosis KZN 1435 8162983 YP_003030737.1 CDS TBMG_00804 NC_012943.1 883961 884635 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 883961..884635 Mycobacterium tuberculosis KZN 1435 8161042 YP_003030738.1 CDS TBMG_00805 NC_012943.1 884652 885251 R hypothetical protein complement(884652..885251) Mycobacterium tuberculosis KZN 1435 8161045 YP_003030739.1 CDS TBMG_00806 NC_012943.1 885273 886001 R hypothetical protein complement(885273..886001) Mycobacterium tuberculosis KZN 1435 8161046 YP_003030740.1 CDS TBMG_00807 NC_012943.1 885998 887041 R hypothetical protein complement(885998..887041) Mycobacterium tuberculosis KZN 1435 8161047 YP_003030741.1 CDS TBMG_00808 NC_012943.1 887038 887847 R GntR family transcriptional regulator complement(887038..887847) Mycobacterium tuberculosis KZN 1435 8161048 YP_003030742.1 CDS TBMG_00809 NC_012943.1 887920 888225 D hypothetical protein 887920..888225 Mycobacterium tuberculosis KZN 1435 8161049 YP_003030743.1 CDS TBMG_00810 NC_012943.1 888338 889837 R oxidoreductase complement(888338..889837) Mycobacterium tuberculosis KZN 1435 8161050 YP_003030744.1 CDS TBMG_04000 NC_012943.1 890173 890391 D transposase 890173..890391 Mycobacterium tuberculosis KZN 1435 8161051 YP_003030745.1 CDS TBMG_00811 NC_012943.1 890413 891324 D transposase 890413..891324 Mycobacterium tuberculosis KZN 1435 8161052 YP_003030746.1 CDS TBMG_00812 NC_012943.1 891314 892111 R hypothetical protein complement(891314..892111) Mycobacterium tuberculosis KZN 1435 8161053 YP_003030747.1 CDS TBMG_00813 NC_012943.1 892108 893115 R hypothetical protein complement(892108..893115) Mycobacterium tuberculosis KZN 1435 8161054 YP_003030748.1 CDS TBMG_00814 NC_012943.1 893160 894461 D catalyzes the removal of amino acids from the N termini of peptides; aminopeptidase 2 893160..894461 Mycobacterium tuberculosis KZN 1435 8161055 YP_003030749.1 CDS TBMG_00815 NC_012943.1 894473 894820 D hypothetical protein 894473..894820 Mycobacterium tuberculosis KZN 1435 8161056 YP_003030750.1 CDS TBMG_00816 NC_012943.1 894814 895470 R hypothetical protein complement(894814..895470) Mycobacterium tuberculosis KZN 1435 8161057 YP_003030751.1 CDS TBMG_00817 NC_012943.1 895662 897926 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 895662..897926 Mycobacterium tuberculosis KZN 1435 8161058 YP_003030752.1 CDS TBMG_00818 NC_012943.1 897923 898552 D hypothetical protein 897923..898552 Mycobacterium tuberculosis KZN 1435 8161059 YP_003030753.1 CDS TBMG_00819 NC_012943.1 898673 899629 D hypothetical protein 898673..899629 Mycobacterium tuberculosis KZN 1435 8161060 YP_003030754.1 CDS TBMG_00820 NC_012943.1 899574 901172 R UDP-glucose-4-epimerase cpsY complement(899574..901172) Mycobacterium tuberculosis KZN 1435 8161061 YP_003030755.1 CDS TBMG_00821 NC_012943.1 901477 901866 D hypothetical protein 901477..901866 Mycobacterium tuberculosis KZN 1435 8161062 YP_003030756.1 CDS TBMG_00822 NC_012943.1 901953 903536 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 901953..903536 Mycobacterium tuberculosis KZN 1435 8161063 YP_003030757.1 CDS TBMG_00823 NC_012943.1 903567 904661 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 903567..904661 Mycobacterium tuberculosis KZN 1435 8161064 YP_003030758.1 CDS TBMG_00824 NC_012943.1 904747 904929 R hypothetical protein complement(904747..904929) Mycobacterium tuberculosis KZN 1435 8161065 YP_003030759.1 CDS TBMG_00825 NC_012943.1 905076 906182 R hypothetical protein complement(905076..906182) Mycobacterium tuberculosis KZN 1435 8161066 YP_003030760.1 CDS TBMG_00826 NC_012943.1 906247 907134 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 906247..907134 Mycobacterium tuberculosis KZN 1435 8161067 YP_003030761.1 CDS TBMG_00827 NC_012943.1 907180 907860 R hypothetical protein complement(907180..907860) Mycobacterium tuberculosis KZN 1435 8161068 YP_003030762.1 CDS TBMG_00828 NC_012943.1 908023 908325 R hypothetical protein complement(908023..908325) Mycobacterium tuberculosis KZN 1435 8161069 YP_003030763.1 CDS TBMG_00829 NC_012943.1 908327 909160 R thiosulfate sulfurtransferase cysA2 complement(908327..909160) Mycobacterium tuberculosis KZN 1435 8161070 YP_003030764.1 CDS TBMG_00830 NC_012943.1 909453 909875 R thioredoxin thiX complement(909453..909875) Mycobacterium tuberculosis KZN 1435 8161071 YP_003030765.1 CDS TBMG_00831 NC_012943.1 909872 910684 R hypothetical protein complement(909872..910684) Mycobacterium tuberculosis KZN 1435 8161072 YP_003030766.1 CDS TBMG_00832 NC_012943.1 910814 911581 D transcriptional regulator 910814..911581 Mycobacterium tuberculosis KZN 1435 8161073 YP_003030767.1 CDS TBMG_00833 NC_012943.1 911578 912525 D mycothiol biosynthesis acetyltransferase 911578..912525 Mycobacterium tuberculosis KZN 1435 8161074 YP_003030768.1 CDS TBMG_00834 NC_012943.1 912568 913344 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 912568..913344 Mycobacterium tuberculosis KZN 1435 8161075 YP_003030769.1 CDS TBMG_00835 NC_012943.1 913400 914041 R phosphate-transport system transcriptional regulator phoY2 complement(913400..914041) Mycobacterium tuberculosis KZN 1435 8161076 YP_003030770.1 CDS TBMG_00836 NC_012943.1 914099 916153 R hypothetical protein complement(914099..916153) Mycobacterium tuberculosis KZN 1435 8161077 YP_003030771.1 CDS TBMG_00837 NC_012943.1 916319 917488 R transcriptional regulator complement(916319..917488) Mycobacterium tuberculosis KZN 1435 8161078 YP_003030772.1 CDS TBMG_00838 NC_012943.1 917576 918592 R acyl-ACP desaturase complement(917576..918592) Mycobacterium tuberculosis KZN 1435 8161079 YP_003030773.1 CDS TBMG_00839 NC_012943.1 918754 919413 R hypothetical protein complement(918754..919413) Mycobacterium tuberculosis KZN 1435 8161080 YP_003030774.1 CDS TBMG_00840 NC_012943.1 919476 920531 D hypothetical protein 919476..920531 Mycobacterium tuberculosis KZN 1435 8161081 YP_003030775.1 CDS TBMG_00841 NC_012943.1 920583 920975 R transcriptional regulator complement(920583..920975) Mycobacterium tuberculosis KZN 1435 8161082 YP_003030776.1 CDS TBMG_00842 NC_012943.1 921033 921455 R deaminase complement(921033..921455) Mycobacterium tuberculosis KZN 1435 8161083 YP_003030777.1 CDS TBMG_00843 NC_012943.1 921417 921707 D transposase 921417..921707 Mycobacterium tuberculosis KZN 1435 8161085 YP_003030778.1 CDS TBMG_00844 NC_012943.1 921812 922717 D hypothetical protein 921812..922717 Mycobacterium tuberculosis KZN 1435 8161084 YP_003030779.1 CDS TBMG_00845 NC_012943.1 922736 923551 R hypothetical protein complement(922736..923551) Mycobacterium tuberculosis KZN 1435 8161086 YP_003030780.1 CDS TBMG_00846 NC_012943.1 924793 925206 D PE-PGRS family protein 924793..925206 Mycobacterium tuberculosis KZN 1435 8161091 YP_003030781.1 CDS TBMG_00847 NC_012943.1 925203 927452 D PE-PGRS family protein 925203..927452 Mycobacterium tuberculosis KZN 1435 8161092 YP_003030782.1 CDS TBMG_00848 NC_012943.1 927679 930327 R PE-PGRS family protein complement(927679..930327) Mycobacterium tuberculosis KZN 1435 8161093 YP_003030783.1 CDS TBMG_00849 NC_012943.1 930795 931439 D hypothetical protein 930795..931439 Mycobacterium tuberculosis KZN 1435 8161094 YP_003030784.1 CDS TBMG_00850 NC_012943.1 931420 931971 R hypothetical protein complement(931420..931971) Mycobacterium tuberculosis KZN 1435 8161095 YP_003030785.1 CDS TBMG_00851 NC_012943.1 932089 932973 R transposase complement(932089..932973) Mycobacterium tuberculosis KZN 1435 8161096 YP_003030786.1 CDS TBMG_00852 NC_012943.1 933024 933350 R transposase complement(933024..933350) Mycobacterium tuberculosis KZN 1435 8161097 YP_003030787.1 CDS TBMG_00853 NC_012943.1 933399 933701 R HAD superfamily hydrolase complement(933399..933701) Mycobacterium tuberculosis KZN 1435 8161098 YP_003030788.1 CDS TBMG_00854 NC_012943.1 933824 934075 R molybdenum cofactor biosynthesis protein D moaD1 complement(933824..934075) Mycobacterium tuberculosis KZN 1435 8161099 YP_003030789.1 CDS moaC NC_012943.1 934092 934604 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(934092..934604) Mycobacterium tuberculosis KZN 1435 8161100 YP_003030790.1 CDS TBMG_00856 NC_012943.1 934601 934996 R pterin-4-alpha-carbinolamine dehydratase complement(934601..934996) Mycobacterium tuberculosis KZN 1435 8161101 YP_003030791.1 CDS TBMG_00857 NC_012943.1 935047 936126 R molybdenum cofactor biosynthesis protein A moaA1 complement(935047..936126) Mycobacterium tuberculosis KZN 1435 8161102 YP_003030792.1 CDS TBMG_00858 NC_012943.1 936275 936715 R hypothetical protein complement(936275..936715) Mycobacterium tuberculosis KZN 1435 8161103 YP_003030793.1 CDS TBMG_00859 NC_012943.1 936814 938397 D alkyldihydroxyacetonephosphate synthase agpS 936814..938397 Mycobacterium tuberculosis KZN 1435 8161104 YP_003030794.1 CDS TBMG_00860 NC_012943.1 938398 939768 R NADPH:adrenodoxin oxidoreductase fprA complement(938398..939768) Mycobacterium tuberculosis KZN 1435 8161105 YP_003030795.1 CDS prfB NC_012943.1 939872 941008 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 939872..941008 Mycobacterium tuberculosis KZN 1435 8161106 YP_003030796.1 CDS TBMG_00862 NC_012943.1 940998 941924 D hypothetical protein 940998..941924 Mycobacterium tuberculosis KZN 1435 8161107 YP_003030797.1 CDS TBMG_00863 NC_012943.1 941887 942363 D hypothetical protein 941887..942363 Mycobacterium tuberculosis KZN 1435 8161108 YP_003030798.1 CDS TBMG_00864 NC_012943.1 942407 943096 D cell division ATP-binding protein ftsE 942407..943096 Mycobacterium tuberculosis KZN 1435 8161109 YP_003030799.1 CDS TBMG_00865 NC_012943.1 943097 943990 D cell division protein ftsX 943097..943990 Mycobacterium tuberculosis KZN 1435 8161110 YP_003030800.1 CDS smpB NC_012943.1 943993 944475 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 943993..944475 Mycobacterium tuberculosis KZN 1435 8161111 YP_003030801.1 CDS TBMG_00867 NC_012943.1 944512 945363 D hypothetical protein 944512..945363 Mycobacterium tuberculosis KZN 1435 8161112 YP_003030802.1 CDS TBMG_00868 NC_012943.1 945850 946170 R hypothetical protein complement(945850..946170) Mycobacterium tuberculosis KZN 1435 8161113 YP_003030803.1 CDS TBMG_00869 NC_012943.1 946114 946566 D hypothetical protein 946114..946566 Mycobacterium tuberculosis KZN 1435 8161115 YP_003030804.1 CDS TBMG_00870 NC_012943.1 946685 947998 D PE-PGRS family protein 946685..947998 Mycobacterium tuberculosis KZN 1435 8161114 YP_003030805.1 CDS TBMG_00871 NC_012943.1 948090 949229 R hypothetical protein complement(948090..949229) Mycobacterium tuberculosis KZN 1435 8161116 YP_003030806.1 CDS TBMG_00872 NC_012943.1 949327 949803 R transcriptional regulator complement(949327..949803) Mycobacterium tuberculosis KZN 1435 8161117 YP_003030807.1 CDS TBMG_00873 NC_012943.1 949885 951015 D hypothetical protein 949885..951015 Mycobacterium tuberculosis KZN 1435 8161118 YP_003030808.1 CDS TBMG_00874 NC_012943.1 951012 952016 D oxidoreductase 951012..952016 Mycobacterium tuberculosis KZN 1435 8161119 YP_003030809.1 CDS TBMG_00875 NC_012943.1 952042 952962 D hypothetical protein 952042..952962 Mycobacterium tuberculosis KZN 1435 8161120 YP_003030810.1 CDS TBMG_00876 NC_012943.1 952969 954660 R hypothetical protein complement(952969..954660) Mycobacterium tuberculosis KZN 1435 8161121 YP_003030811.1 CDS TBMG_00877 NC_012943.1 954678 955565 R hypothetical protein complement(954678..955565) Mycobacterium tuberculosis KZN 1435 8161122 YP_003030812.1 CDS TBMG_00878 NC_012943.1 956504 958015 R fatty-acid-CoA ligase fadD13 complement(956504..958015) Mycobacterium tuberculosis KZN 1435 8161123 YP_003030813.1 CDS TBMG_00879 NC_012943.1 958012 959436 R hypothetical protein complement(958012..959436) Mycobacterium tuberculosis KZN 1435 8161124 YP_003030814.1 CDS TBMG_00880 NC_012943.1 959433 960854 R hypothetical protein complement(959433..960854) Mycobacterium tuberculosis KZN 1435 8161125 YP_003030815.1 CDS TBMG_00881 NC_012943.1 960889 961995 R zinc-type alcohol dehydrogenase adhD complement(960889..961995) Mycobacterium tuberculosis KZN 1435 8161043 YP_003030816.1 CDS TBMG_00882 NC_012943.1 962026 962856 R short-chain type dehydrogenase/reductase complement(962026..962856) Mycobacterium tuberculosis KZN 1435 8161044 YP_003030817.1 CDS TBMG_00883 NC_012943.1 962853 963779 R acetyl-hydrolase/esterase lipR complement(962853..963779) Mycobacterium tuberculosis KZN 1435 8163918 YP_003030818.1 CDS TBMG_00884 NC_012943.1 963785 965272 R monooxygenase complement(963785..965272) Mycobacterium tuberculosis KZN 1435 8163919 YP_003030819.1 CDS TBMG_00885 NC_012943.1 965347 966372 D AraC family transcriptional regulator 965347..966372 Mycobacterium tuberculosis KZN 1435 8163920 YP_003030820.1 CDS TBMG_00886 NC_012943.1 966498 967736 R hypothetical protein complement(966498..967736) Mycobacterium tuberculosis KZN 1435 8163921 YP_003030821.1 CDS TBMG_00887 NC_012943.1 967788 971120 D serine/threonine-protein kinase transcriptional regulator pknK 967788..971120 Mycobacterium tuberculosis KZN 1435 8163922 YP_003030822.1 CDS TBMG_00888 NC_012943.1 971179 972006 D hypothetical protein 971179..972006 Mycobacterium tuberculosis KZN 1435 8163923 YP_003030823.1 CDS TBMG_00889 NC_012943.1 972022 972423 R hydroxylaminobenzene mutase hab complement(972022..972423) Mycobacterium tuberculosis KZN 1435 8163924 YP_003030824.1 CDS TBMG_00890 NC_012943.1 972424 974235 R hydrolase complement(972424..974235) Mycobacterium tuberculosis KZN 1435 8163925 YP_003030825.1 CDS TBMG_00891 NC_012943.1 974228 974704 R hypothetical protein complement(974228..974704) Mycobacterium tuberculosis KZN 1435 8163926 YP_003030826.1 CDS TBMG_00892 NC_012943.1 974803 975726 D hypothetical protein 974803..975726 Mycobacterium tuberculosis KZN 1435 8163927 YP_003030827.1 CDS TBMG_00893 NC_012943.1 975723 976997 R hypothetical protein complement(975723..976997) Mycobacterium tuberculosis KZN 1435 8163928 YP_003030828.1 CDS TBMG_00894 NC_012943.1 977091 977447 D hypothetical protein 977091..977447 Mycobacterium tuberculosis KZN 1435 8163929 YP_003030829.1 CDS TBMG_00895 NC_012943.1 977454 977978 D hypothetical protein 977454..977978 Mycobacterium tuberculosis KZN 1435 8163930 YP_003030830.1 CDS TBMG_00896 NC_012943.1 978203 979312 R hypothetical protein complement(978203..979312) Mycobacterium tuberculosis KZN 1435 8163931 YP_003030831.1 CDS TBMG_00897 NC_012943.1 979309 979689 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(979309..979689) Mycobacterium tuberculosis KZN 1435 8163932 YP_003030832.1 CDS TBMG_00898 NC_012943.1 979686 980084 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(979686..980084) Mycobacterium tuberculosis KZN 1435 8163933 YP_003030833.1 CDS TBMG_00899 NC_012943.1 980154 981797 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 980154..981797 Mycobacterium tuberculosis KZN 1435 8163934 YP_003030834.1 CDS TBMG_00900 NC_012943.1 981938 982348 R hypothetical protein complement(981938..982348) Mycobacterium tuberculosis KZN 1435 8163936 YP_003030835.1 CDS TBMG_00901 NC_012943.1 982461 983069 R transcriptional regulator, deoR-family complement(982461..983069) Mycobacterium tuberculosis KZN 1435 8163937 YP_003030836.1 CDS TBMG_00902 NC_012943.1 983066 983389 R hypothetical protein complement(983066..983389) Mycobacterium tuberculosis KZN 1435 8163938 YP_003030837.1 CDS TBMG_00903 NC_012943.1 983526 983951 D hypothetical protein 983526..983951 Mycobacterium tuberculosis KZN 1435 8163939 YP_003030838.1 CDS TBMG_00904 NC_012943.1 984257 986539 R carbon starvation protein A cstA complement(984257..986539) Mycobacterium tuberculosis KZN 1435 8163940 YP_003030839.1 CDS ligB NC_012943.1 986669 988192 R catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase complement(986669..988192) Mycobacterium tuberculosis KZN 1435 8163941 YP_003030840.1 CDS TBMG_04001 NC_012943.1 988349 988639 D acyl-CoA dehydrogenase 988349..988639 Mycobacterium tuberculosis KZN 1435 8163942 YP_003030841.1 CDS TBMG_00906 NC_012943.1 988659 990461 D acyl-CoA dehydrogenase 988659..990461 Mycobacterium tuberculosis KZN 1435 8163943 YP_003030842.1 CDS TBMG_00907 NC_012943.1 990578 992050 D GntR family transcriptional regulator 990578..992050 Mycobacterium tuberculosis KZN 1435 8163944 YP_003030843.1 CDS TBMG_00908 NC_012943.1 992821 994299 R cytochrome P450 136 cyp136 complement(992821..994299) Mycobacterium tuberculosis KZN 1435 8163945 YP_003030844.1 CDS TBMG_00909 NC_012943.1 994385 995065 D TetR family transcriptional regulator 994385..995065 Mycobacterium tuberculosis KZN 1435 8163946 YP_003030845.1 CDS TBMG_00910 NC_012943.1 995129 995992 D short chain dehydrogenase 995129..995992 Mycobacterium tuberculosis KZN 1435 8163947 YP_003030846.1 CDS TBMG_00911 NC_012943.1 996046 997086 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(996046..997086) Mycobacterium tuberculosis KZN 1435 8163948 YP_003030847.1 CDS TBMG_00912 NC_012943.1 997096 997710 R TetR family transcriptional regulator complement(997096..997710) Mycobacterium tuberculosis KZN 1435 8163949 YP_003030848.1 CDS TBMG_00913 NC_012943.1 997802 998356 D hypothetical protein 997802..998356 Mycobacterium tuberculosis KZN 1435 8163950 YP_003030849.1 CDS TBMG_00914 NC_012943.1 998437 998841 D hypothetical protein 998437..998841 Mycobacterium tuberculosis KZN 1435 8163951 YP_003030850.1 CDS TBMG_00915 NC_012943.1 998819 999058 D glutaredoxin-like electron transporter nrdH 998819..999058 Mycobacterium tuberculosis KZN 1435 8163952 YP_003030851.1 CDS nrdI NC_012943.1 999093 999545 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 999093..999545 Mycobacterium tuberculosis KZN 1435 8163953 YP_003030852.1 CDS TBMG_00917 NC_012943.1 999515 1001692 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 999515..1001692 Mycobacterium tuberculosis KZN 1435 8163954 YP_003030853.1 CDS TBMG_00918 NC_012943.1 1001820 1002560 D transcriptional regulator, asnC-family 1001820..1002560 Mycobacterium tuberculosis KZN 1435 8163955 YP_003030854.1 CDS TBMG_00919 NC_012943.1 1002694 1004268 D monooxygenase 1002694..1004268 Mycobacterium tuberculosis KZN 1435 8163956 YP_003030855.1 CDS nrdF2 NC_012943.1 1004399 1005373 D ribonucleotide-diphosphate reductase subunit beta 1004399..1005373 Mycobacterium tuberculosis KZN 1435 8163957 YP_003030856.1 CDS TBMG_00921 NC_012943.1 1005471 1005755 D hypothetical protein 1005471..1005755 Mycobacterium tuberculosis KZN 1435 8163958 YP_003030857.1 CDS TBMG_00922 NC_012943.1 1006089 1006463 D hypothetical protein 1006089..1006463 Mycobacterium tuberculosis KZN 1435 8163959 YP_003030858.1 CDS TBMG_00923 NC_012943.1 1006452 1007492 R NADP-dependent alcohol dehydrogenase adhC complement(1006452..1007492) Mycobacterium tuberculosis KZN 1435 8163960 YP_003030859.1 CDS TBMG_04002 NC_012943.1 1007562 1008641 R Fe(III)-dicitrate-binding periplasmic lipoprotein fecB complement(1007562..1008641) Mycobacterium tuberculosis KZN 1435 8163961 YP_003030860.1 CDS TBMG_00926 NC_012943.1 1008856 1010577 D cytochrome C oxidase polypeptide I ctaD 1008856..1010577 Mycobacterium tuberculosis KZN 1435 8163962 YP_003030861.1 CDS TBMG_00927 NC_012943.1 1010615 1011844 D phosphoserine phosphatase serB2 1010615..1011844 Mycobacterium tuberculosis KZN 1435 8163963 YP_003030862.1 CDS TBMG_00928 NC_012943.1 1011859 1012722 D ABC transporter ATP-binding protein 1011859..1012722 Mycobacterium tuberculosis KZN 1435 8163964 YP_003030863.1 CDS TBMG_00929 NC_012943.1 1012719 1013585 D hypothetical protein 1012719..1013585 Mycobacterium tuberculosis KZN 1435 8163965 YP_003030864.1 CDS TBMG_00930 NC_012943.1 1013573 1014358 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1013573..1014358 Mycobacterium tuberculosis KZN 1435 8163966 YP_003030865.1 CDS TBMG_00931 NC_012943.1 1014369 1015352 D hypothetical protein 1014369..1015352 Mycobacterium tuberculosis KZN 1435 8163967 YP_003030866.1 CDS TBMG_00932 NC_012943.1 1015487 1016563 D hypothetical protein 1015487..1016563 Mycobacterium tuberculosis KZN 1435 8163968 YP_003030867.1 CDS TBMG_00933 NC_012943.1 1016636 1017319 D hypothetical protein 1016636..1017319 Mycobacterium tuberculosis KZN 1435 8163969 YP_003030868.1 CDS TBMG_00934 NC_012943.1 1017316 1018398 R hypothetical protein complement(1017316..1018398) Mycobacterium tuberculosis KZN 1435 8163970 YP_003030869.1 CDS TBMG_00935 NC_012943.1 1018904 1019758 D transferase 1018904..1019758 Mycobacterium tuberculosis KZN 1435 8163971 YP_003030870.1 CDS TBMG_00936 NC_012943.1 1019849 1020397 R hypothetical protein complement(1019849..1020397) Mycobacterium tuberculosis KZN 1435 8163972 YP_003030871.1 CDS TBMG_04003 NC_012943.1 1020576 1020965 R hypothetical protein complement(1020576..1020965) Mycobacterium tuberculosis KZN 1435 8163973 YP_003030872.1 CDS TBMG_00937 NC_012943.1 1020962 1022230 R transferase complement(1020962..1022230) Mycobacterium tuberculosis KZN 1435 8163974 YP_003030873.1 CDS TBMG_00938 NC_012943.1 1022274 1023854 R hypothetical protein complement(1022274..1023854) Mycobacterium tuberculosis KZN 1435 8163975 YP_003030874.1 CDS TBMG_00939 NC_012943.1 1023851 1024675 R hypothetical protein complement(1023851..1024675) Mycobacterium tuberculosis KZN 1435 8163976 YP_003030875.1 CDS TBMG_00940 NC_012943.1 1024906 1025706 D electron transfer flavoprotein beta subunit fixA 1024906..1025706 Mycobacterium tuberculosis KZN 1435 8163977 YP_003030876.1 CDS TBMG_00941 NC_012943.1 1025745 1026701 D electron transfer flavoprotein alpha subunit fixB 1025745..1026701 Mycobacterium tuberculosis KZN 1435 8163978 YP_003030877.1 CDS TBMG_00942 NC_012943.1 1026857 1027702 D hypothetical protein 1026857..1027702 Mycobacterium tuberculosis KZN 1435 8163979 YP_003030878.1 CDS TBMG_00943 NC_012943.1 1027699 1028613 D hypothetical protein 1027699..1028613 Mycobacterium tuberculosis KZN 1435 8163980 YP_003030879.1 CDS TBMG_00944 NC_012943.1 1028710 1029891 D cysteine desulfurase iscS 1028710..1029891 Mycobacterium tuberculosis KZN 1435 8163981 YP_003030880.1 CDS mnmA NC_012943.1 1029888 1030991 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1029888..1030991 Mycobacterium tuberculosis KZN 1435 8163982 YP_003030881.1 CDS TBMG_00946 NC_012943.1 1031091 1032401 D transposase 1031091..1032401 Mycobacterium tuberculosis KZN 1435 8163983 YP_003030882.1 CDS TBMG_00947 NC_012943.1 1032783 1033097 D PE family protein 1032783..1033097 Mycobacterium tuberculosis KZN 1435 8163984 YP_003030883.1 CDS TBMG_00948 NC_012943.1 1033094 1034401 D PPE family protein 1033094..1034401 Mycobacterium tuberculosis KZN 1435 8163985 YP_003030884.1 CDS TBMG_00949 NC_012943.1 1034433 1034741 D esat-6 like protein esxS 1034433..1034741 Mycobacterium tuberculosis KZN 1435 8163986 YP_003030885.1 CDS TBMG_00950 NC_012943.1 1034776 1035066 D esat-6 like protein esxR 1034776..1035066 Mycobacterium tuberculosis KZN 1435 8163987 YP_003030886.1 CDS TBMG_04004 NC_012943.1 1035106 1035282 D hypothetical protein 1035106..1035282 Mycobacterium tuberculosis KZN 1435 8163988 YP_003030887.1 CDS TBMG_04005 NC_012943.1 1035275 1035448 D hypothetical protein 1035275..1035448 Mycobacterium tuberculosis KZN 1435 8163989 YP_003030888.1 CDS TBMG_00952 NC_012943.1 1035534 1036838 D PPE family protein 1035534..1036838 Mycobacterium tuberculosis KZN 1435 8163990 YP_003030889.1 CDS TBMG_00953 NC_012943.1 1036922 1037287 D esat-6 like protein esxQ 1036922..1037287 Mycobacterium tuberculosis KZN 1435 8163991 YP_003030890.1 CDS TBMG_00954 NC_012943.1 1037390 1038019 R hypothetical protein complement(1037390..1038019) Mycobacterium tuberculosis KZN 1435 8163992 YP_003030891.1 CDS TBMG_00955 NC_012943.1 1038113 1039126 D hypothetical protein 1038113..1039126 Mycobacterium tuberculosis KZN 1435 8163993 YP_003030892.1 CDS TBMG_00956 NC_012943.1 1039810 1041234 D truncated CDS; NAD-dependent DNA ligase ligA 1039810..1041234 Mycobacterium tuberculosis KZN 1435 8163994 YP_003030893.1 CDS TBMG_00957 NC_012943.1 1041308 1042030 R hypothetical protein complement(1041308..1042030) Mycobacterium tuberculosis KZN 1435 8163995 YP_003030894.1 CDS gatC NC_012943.1 1042049 1042348 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1042049..1042348 Mycobacterium tuberculosis KZN 1435 8163996 YP_003030895.1 CDS gatA NC_012943.1 1042345 1043829 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1042345..1043829 Mycobacterium tuberculosis KZN 1435 8163997 YP_003030896.1 CDS TBMG_00960 NC_012943.1 1043925 1044956 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1043925..1044956 Mycobacterium tuberculosis KZN 1435 8163998 YP_003030897.1 CDS gatB NC_012943.1 1044986 1046515 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1044986..1046515 Mycobacterium tuberculosis KZN 1435 8163999 YP_003030898.1 CDS TBMG_00962 NC_012943.1 1046512 1047135 R hypothetical protein complement(1046512..1047135) Mycobacterium tuberculosis KZN 1435 8162246 YP_003030899.1 CDS TBMG_00963 NC_012943.1 1047329 1047943 D oxidoreductase 1047329..1047943 Mycobacterium tuberculosis KZN 1435 8162251 YP_003030900.1 CDS TBMG_00964 NC_012943.1 1047949 1049133 R hypothetical protein complement(1047949..1049133) Mycobacterium tuberculosis KZN 1435 8162252 YP_003030901.1 CDS TBMG_00965 NC_012943.1 1049247 1050086 D hypothetical protein 1049247..1050086 Mycobacterium tuberculosis KZN 1435 8162253 YP_003030902.1 CDS TBMG_00966 NC_012943.1 1050093 1050431 R low molecular weight protein antigen 6 cfp6 complement(1050093..1050431) Mycobacterium tuberculosis KZN 1435 8162254 YP_003030903.1 CDS TBMG_00967 NC_012943.1 1050793 1052649 D acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit 1050793..1052649 Mycobacterium tuberculosis KZN 1435 8162255 YP_003030904.1 CDS ilvH NC_012943.1 1052649 1053155 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1052649..1053155 Mycobacterium tuberculosis KZN 1435 8162256 YP_003030905.1 CDS TBMG_00969 NC_012943.1 1053181 1054194 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1053181..1054194 Mycobacterium tuberculosis KZN 1435 8162257 YP_003030906.1 CDS TBMG_00970 NC_012943.1 1054508 1055167 R hypothetical protein complement(1054508..1055167) Mycobacterium tuberculosis KZN 1435 8162258 YP_003030907.1 CDS TBMG_00971 NC_012943.1 1055212 1056192 R hypothetical protein complement(1055212..1056192) Mycobacterium tuberculosis KZN 1435 8162259 YP_003030908.1 CDS TBMG_04006 NC_012943.1 1056351 1056554 D hypothetical protein 1056351..1056554 Mycobacterium tuberculosis KZN 1435 8162260 YP_003030909.1 CDS TBMG_00972 NC_012943.1 1056503 1056964 R hypothetical protein complement(1056503..1056964) Mycobacterium tuberculosis KZN 1435 8162261 YP_003030910.1 CDS TBMG_04007 NC_012943.1 1056846 1057046 D hypothetical protein 1056846..1057046 Mycobacterium tuberculosis KZN 1435 8162263 YP_003030911.1 CDS TBMG_00973 NC_012943.1 1057238 1058680 R hypothetical protein complement(1057238..1058680) Mycobacterium tuberculosis KZN 1435 8162262 YP_003030912.1 CDS TBMG_00974 NC_012943.1 1058710 1060296 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1058710..1060296 Mycobacterium tuberculosis KZN 1435 8162264 YP_003030913.1 CDS TBMG_00975 NC_012943.1 1060311 1061321 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1060311..1061321 Mycobacterium tuberculosis KZN 1435 8162265 YP_003030914.1 CDS TBMG_04008 NC_012943.1 1061173 1062510 R hypothetical protein complement(1061173..1062510) Mycobacterium tuberculosis KZN 1435 8162266 YP_003030915.1 CDS TBMG_00976 NC_012943.1 1062660 1063505 D 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 1062660..1063505 Mycobacterium tuberculosis KZN 1435 8162267 YP_003030916.1 CDS gltX NC_012943.1 1063502 1064974 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1063502..1064974 Mycobacterium tuberculosis KZN 1435 8162268 YP_003030917.1 CDS TBMG_00978 NC_012943.1 1065306 1065797 R hypothetical protein complement(1065306..1065797) Mycobacterium tuberculosis KZN 1435 8162271 YP_003030918.1 CDS TBMG_00979 NC_012943.1 1066060 1066920 D hypothetical protein 1066060..1066920 Mycobacterium tuberculosis KZN 1435 8162272 YP_003030919.1 CDS TBMG_00980 NC_012943.1 1066931 1067632 R transcriptional regulator complement(1066931..1067632) Mycobacterium tuberculosis KZN 1435 8162273 YP_003030920.1 CDS TBMG_00981 NC_012943.1 1067704 1069125 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1067704..1069125 Mycobacterium tuberculosis KZN 1435 8162274 YP_003030921.1 CDS leuD NC_012943.1 1069150 1069746 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1069150..1069746 Mycobacterium tuberculosis KZN 1435 8162275 YP_003030922.1 CDS TBMG_00983 NC_012943.1 1069959 1070603 D histone-like DNA-binding protein hupB 1069959..1070603 Mycobacterium tuberculosis KZN 1435 8162276 YP_003030923.1 CDS TBMG_00984 NC_012943.1 1070661 1071614 R hydrolase mutT1 complement(1070661..1071614) Mycobacterium tuberculosis KZN 1435 8162277 YP_003030924.1 CDS TBMG_00985 NC_012943.1 1071697 1073925 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(1071697..1073925) Mycobacterium tuberculosis KZN 1435 8162278 YP_003030925.1 CDS TBMG_00986 NC_012943.1 1074017 1074688 R hypothetical protein complement(1074017..1074688) Mycobacterium tuberculosis KZN 1435 8162279 YP_003030926.1 CDS gpsA NC_012943.1 1074780 1075784 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1074780..1075784 Mycobacterium tuberculosis KZN 1435 8162280 YP_003030927.1 CDS ddl NC_012943.1 1075907 1076983 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1075907..1076983 Mycobacterium tuberculosis KZN 1435 8162281 YP_003030928.1 CDS TBMG_00989 NC_012943.1 1077099 1077674 R hypothetical protein complement(1077099..1077674) Mycobacterium tuberculosis KZN 1435 8162282 YP_003030929.1 CDS TBMG_00990 NC_012943.1 1077856 1078440 D resolvase 1077856..1078440 Mycobacterium tuberculosis KZN 1435 8162283 YP_003030930.1 CDS TBMG_00991 NC_012943.1 1078440 1079819 D transposase 1078440..1079819 Mycobacterium tuberculosis KZN 1435 8162284 YP_003030931.1 CDS TBMG_00992 NC_012943.1 1079816 1080817 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 1079816..1080817 Mycobacterium tuberculosis KZN 1435 8162285 YP_003030932.1 CDS TBMG_00993 NC_012943.1 1080850 1081533 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1080850..1081533 Mycobacterium tuberculosis KZN 1435 8162286 YP_003030933.1 CDS rpmB NC_012943.1 1081556 1081750 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1081556..1081750) Mycobacterium tuberculosis KZN 1435 8162287 YP_003030934.1 CDS TBMG_00995 NC_012943.1 1081992 1082246 D hypothetical protein 1081992..1082246 Mycobacterium tuberculosis KZN 1435 8162288 YP_003030935.1 CDS TBMG_00996 NC_012943.1 1082243 1083655 D hypothetical protein 1082243..1083655 Mycobacterium tuberculosis KZN 1435 8162289 YP_003030936.1 CDS TBMG_00997 NC_012943.1 1083658 1085871 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1083658..1085871 Mycobacterium tuberculosis KZN 1435 8162290 YP_003030937.1 CDS TBMG_00998 NC_012943.1 1085868 1086581 D hypothetical protein 1085868..1086581 Mycobacterium tuberculosis KZN 1435 8162291 YP_003030938.1 CDS TBMG_00999 NC_012943.1 1086655 1087503 R oxidoreductase complement(1086655..1087503) Mycobacterium tuberculosis KZN 1435 8162292 YP_003030939.1 CDS TBMG_01000 NC_012943.1 1087901 1089031 D lipase/esterase 1087901..1089031 Mycobacterium tuberculosis KZN 1435 8162293 YP_003030940.1 CDS TBMG_01001 NC_012943.1 1089110 1089895 D hypothetical protein 1089110..1089895 Mycobacterium tuberculosis KZN 1435 8162294 YP_003030941.1 CDS TBMG_01002 NC_012943.1 1089901 1090533 D hypothetical protein 1089901..1090533 Mycobacterium tuberculosis KZN 1435 8162295 YP_003030942.1 CDS TBMG_01003 NC_012943.1 1090558 1093941 D biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1090558..1093941 Mycobacterium tuberculosis KZN 1435 8162296 YP_003030943.1 CDS TBMG_01004 NC_012943.1 1094137 1094703 D methyltransferase/methylase 1094137..1094703 Mycobacterium tuberculosis KZN 1435 8162297 YP_003030944.1 CDS coaD NC_012943.1 1094789 1095274 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1094789..1095274 Mycobacterium tuberculosis KZN 1435 8162298 YP_003030945.1 CDS TBMG_04009 NC_012943.1 1095318 1095503 R hypothetical protein complement(1095318..1095503) Mycobacterium tuberculosis KZN 1435 8162299 YP_003030946.1 CDS TBMG_01006 NC_012943.1 1095619 1096137 R hypothetical protein complement(1095619..1096137) Mycobacterium tuberculosis KZN 1435 8162300 YP_003030947.1 CDS purU NC_012943.1 1096143 1097075 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1096143..1097075) Mycobacterium tuberculosis KZN 1435 8162301 YP_003030948.1 CDS TBMG_01008 NC_012943.1 1097148 1098368 R hypothetical protein complement(1097148..1098368) Mycobacterium tuberculosis KZN 1435 8162302 YP_003030949.1 CDS TBMG_04010 NC_012943.1 1099004 1099831 D truncated CDS; glycosyltransferase 1099004..1099831 Mycobacterium tuberculosis KZN 1435 8162303 YP_003030950.1 CDS TBMG_01010 NC_012943.1 1099932 1100321 R transposase complement(1099932..1100321) Mycobacterium tuberculosis KZN 1435 8162304 YP_003030951.1 CDS TBMG_01011 NC_012943.1 1100403 1100651 D hypothetical protein 1100403..1100651 Mycobacterium tuberculosis KZN 1435 8162305 YP_003030952.1 CDS TBMG_01012 NC_012943.1 1100766 1101503 D methyltransferase/methylase 1100766..1101503 Mycobacterium tuberculosis KZN 1435 8162306 YP_003030953.1 CDS TBMG_01013 NC_012943.1 1101604 1102890 D glycosyltransferase 1101604..1102890 Mycobacterium tuberculosis KZN 1435 8162307 YP_003030954.1 CDS TBMG_01014 NC_012943.1 1103307 1104134 R glycosyltransferase complement(1103307..1104134) Mycobacterium tuberculosis KZN 1435 8162308 YP_003030955.1 CDS TBMG_01015 NC_012943.1 1104205 1104936 R hypothetical protein complement(1104205..1104936) Mycobacterium tuberculosis KZN 1435 8162309 YP_003030956.1 CDS TBMG_01016 NC_012943.1 1105050 1106024 D hypothetical protein 1105050..1106024 Mycobacterium tuberculosis KZN 1435 8162310 YP_003030957.1 CDS TBMG_01017 NC_012943.1 1106213 1106938 D hypothetical protein 1106213..1106938 Mycobacterium tuberculosis KZN 1435 8162311 YP_003030958.1 CDS TBMG_01018 NC_012943.1 1107069 1108325 R hypothetical protein complement(1107069..1108325) Mycobacterium tuberculosis KZN 1435 8162312 YP_003030959.1 CDS TBMG_01019 NC_012943.1 1108351 1109163 R methyltransferase/methylase complement(1108351..1109163) Mycobacterium tuberculosis KZN 1435 8162313 YP_003030960.1 CDS TBMG_01020 NC_012943.1 1109356 1110501 D oxidoreductase 1109356..1110501 Mycobacterium tuberculosis KZN 1435 8162314 YP_003030961.1 CDS TBMG_01021 NC_012943.1 1111149 1113008 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1111149..1113008 Mycobacterium tuberculosis KZN 1435 8162315 YP_003030962.1 CDS TBMG_01022 NC_012943.1 1113034 1113633 D hypothetical protein 1113034..1113633 Mycobacterium tuberculosis KZN 1435 8162316 YP_003030963.1 CDS TBMG_01023 NC_012943.1 1113650 1115767 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1113650..1115767 Mycobacterium tuberculosis KZN 1435 8162317 YP_003030964.1 CDS TBMG_01024 NC_012943.1 1115764 1116966 D polyketide synthase 1115764..1116966 Mycobacterium tuberculosis KZN 1435 8162318 YP_003030965.1 CDS TBMG_01025 NC_012943.1 1116963 1117253 D polyketide synthase 1116963..1117253 Mycobacterium tuberculosis KZN 1435 8162319 YP_003030966.1 CDS TBMG_01026 NC_012943.1 1117238 1122100 D polyketide synthase 1117238..1122100 Mycobacterium tuberculosis KZN 1435 8162320 YP_003030967.1 CDS TBMG_01027 NC_012943.1 1122278 1122979 D hypothetical protein 1122278..1122979 Mycobacterium tuberculosis KZN 1435 8162321 YP_003030968.1 CDS TBMG_04011 NC_012943.1 1123097 1123636 R transposase complement(1123097..1123636) Mycobacterium tuberculosis KZN 1435 8162322 YP_003030969.1 CDS TBMG_04012 NC_012943.1 1123368 1123898 R transposase complement(1123368..1123898) Mycobacterium tuberculosis KZN 1435 8162323 YP_003030970.1 CDS TBMG_01029 NC_012943.1 1123898 1125139 R transposase complement(1123898..1125139) Mycobacterium tuberculosis KZN 1435 8162324 YP_003030971.1 CDS TBMG_01030 NC_012943.1 1125771 1128533 R transmembrane transporter mmpL7 complement(1125771..1128533) Mycobacterium tuberculosis KZN 1435 8162325 YP_003030972.1 CDS TBMG_01031 NC_012943.1 1128526 1130268 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(1128526..1130268) Mycobacterium tuberculosis KZN 1435 8162326 YP_003030973.1 CDS TBMG_01032 NC_012943.1 1130888 1137223 D multifunctional mycocerosic acid synthase membrane-associated mas 1130888..1137223 Mycobacterium tuberculosis KZN 1435 8162327 YP_003030974.1 CDS TBMG_01033 NC_012943.1 1137386 1138654 R required for PDIM synthesis; phthiocerol and phthiodiolone dimycocerosate esters are scaffolds used for virulence-enhancing lipids; proposed to catalyze diesterification of phthiocerol and phthiodolone with mycocerosate; functions in polyketide synthesis; acyltransferase complement(1137386..1138654) Mycobacterium tuberculosis KZN 1435 8162328 YP_003030975.1 CDS TBMG_01034 NC_012943.1 1138701 1139531 R hypothetical protein complement(1138701..1139531) Mycobacterium tuberculosis KZN 1435 8162329 YP_003030976.1 CDS TBMG_01035 NC_012943.1 1139528 1140397 R hypothetical protein complement(1139528..1140397) Mycobacterium tuberculosis KZN 1435 8162330 YP_003030977.1 CDS TBMG_01036 NC_012943.1 1140394 1141410 R daunorubicin-dim-transport ATP-binding protein ABC transporter drrA complement(1140394..1141410) Mycobacterium tuberculosis KZN 1435 8162331 YP_003030978.1 CDS TBMG_01037 NC_012943.1 1141400 1145866 R phenolpthiocerol synthesis type-I polyketide synthase ppsE complement(1141400..1145866) Mycobacterium tuberculosis KZN 1435 8162247 YP_003030979.1 CDS TBMG_01038 NC_012943.1 1147139 1151356 R truncated CDS; phenolpthiocerol synthesis type-I polyketide synthase ppsD complement(1147139..1151356) Mycobacterium tuberculosis KZN 1435 8162248 YP_003030980.1 CDS TBMG_01039 NC_012943.1 1151353 1157919 R phenolpthiocerol synthesis type-I polyketide synthase ppsC complement(1151353..1157919) Mycobacterium tuberculosis KZN 1435 8162249 YP_003030981.1 CDS TBMG_01040 NC_012943.1 1157916 1162532 R phenolpthiocerol synthesis type-I polyketide synthase ppsB complement(1157916..1162532) Mycobacterium tuberculosis KZN 1435 8162250 YP_003030982.1 CDS TBMG_01041 NC_012943.1 1164603 1168160 R truncated CDS; phenolpthiocerol synthesis type-I polyketide synthase ppsA complement(1164603..1168160) Mycobacterium tuberculosis KZN 1435 8164322 YP_003030983.1 CDS TBMG_01042 NC_012943.1 1168157 1170037 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(1168157..1170037) Mycobacterium tuberculosis KZN 1435 8164412 YP_003030984.1 CDS TBMG_01043 NC_012943.1 1170622 1171407 R thioesterase tesA complement(1170622..1171407) Mycobacterium tuberculosis KZN 1435 8164413 YP_003030985.1 CDS TBMG_01044 NC_012943.1 1171646 1172383 D hypothetical protein 1171646..1172383 Mycobacterium tuberculosis KZN 1435 8164414 YP_003030986.1 CDS TBMG_01045 NC_012943.1 1172434 1173057 D hypothetical protein 1172434..1173057 Mycobacterium tuberculosis KZN 1435 8164415 YP_003030987.1 CDS rnc NC_012943.1 1173054 1173776 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1173054..1173776 Mycobacterium tuberculosis KZN 1435 8164416 YP_003030988.1 CDS TBMG_01047 NC_012943.1 1174135 1175004 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1174135..1175004 Mycobacterium tuberculosis KZN 1435 8164417 YP_003030989.1 CDS TBMG_01048 NC_012943.1 1175106 1175519 D hypothetical protein 1175106..1175519 Mycobacterium tuberculosis KZN 1435 8164418 YP_003030990.1 CDS TBMG_01049 NC_012943.1 1175506 1175787 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1175506..1175787 Mycobacterium tuberculosis KZN 1435 8164419 YP_003030991.1 CDS TBMG_01050 NC_012943.1 1175799 1179416 D chromosome partition protein smc 1175799..1179416 Mycobacterium tuberculosis KZN 1435 8164420 YP_003030992.1 CDS TBMG_01051 NC_012943.1 1179466 1180734 D cell division protein ftsY 1179466..1180734 Mycobacterium tuberculosis KZN 1435 8164421 YP_003030993.1 CDS TBMG_01052 NC_012943.1 1181323 1182756 D hypothetical protein 1181323..1182756 Mycobacterium tuberculosis KZN 1435 8164422 YP_003030994.1 CDS TBMG_01053 NC_012943.1 1182753 1183091 D nitrogen regulatory protein P-II glnB 1182753..1183091 Mycobacterium tuberculosis KZN 1435 8164423 YP_003030995.1 CDS TBMG_01054 NC_012943.1 1183149 1184585 D truncated CDS; PII uridylyl-transferase 1183149..1184585 Mycobacterium tuberculosis KZN 1435 8164424 YP_003030996.1 CDS TBMG_01055 NC_012943.1 1185585 1187465 R hypothetical protein complement(1185585..1187465) Mycobacterium tuberculosis KZN 1435 8164425 YP_003030997.1 CDS TBMG_01056 NC_012943.1 1187543 1189120 D signal recognition particle protein ffh 1187543..1189120 Mycobacterium tuberculosis KZN 1435 8164426 YP_003030998.1 CDS TBMG_01057 NC_012943.1 1189148 1190260 D hypothetical protein 1189148..1190260 Mycobacterium tuberculosis KZN 1435 8164427 YP_003030999.1 CDS TBMG_01058 NC_012943.1 1190304 1192061 D Ser/Thr protein kinase 1190304..1192061 Mycobacterium tuberculosis KZN 1435 8164428 YP_003031000.1 CDS TBMG_01059 NC_012943.1 1192130 1193965 D D-amino acid aminohydrolase 1192130..1193965 Mycobacterium tuberculosis KZN 1435 8164429 YP_003031001.1 CDS TBMG_01060 NC_012943.1 1193967 1194554 D TetR family transcriptional regulator 1193967..1194554 Mycobacterium tuberculosis KZN 1435 8164430 YP_003031002.1 CDS TBMG_01061 NC_012943.1 1194614 1195489 R D-alanyl-D-alanine carboxypeptidase dacB2 complement(1194614..1195489) Mycobacterium tuberculosis KZN 1435 8164431 YP_003031003.1 CDS TBMG_01062 NC_012943.1 1195558 1196001 D hypothetical protein 1195558..1196001 Mycobacterium tuberculosis KZN 1435 8164432 YP_003031004.1 CDS rpsP NC_012943.1 1196185 1196673 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1196185..1196673 Mycobacterium tuberculosis KZN 1435 8164433 YP_003031005.1 CDS TBMG_01064 NC_012943.1 1196681 1196923 D hypothetical protein 1196681..1196923 Mycobacterium tuberculosis KZN 1435 8164434 YP_003031006.1 CDS rimM NC_012943.1 1196937 1197467 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1196937..1197467 Mycobacterium tuberculosis KZN 1435 8164435 YP_003031007.1 CDS trmD NC_012943.1 1197471 1198163 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1197471..1198163 Mycobacterium tuberculosis KZN 1435 8164436 YP_003031008.1 CDS TBMG_01067 NC_012943.1 1198256 1199200 R hypothetical protein complement(1198256..1199200) Mycobacterium tuberculosis KZN 1435 8164437 YP_003031009.1 CDS rplS NC_012943.1 1199575 1199916 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1199575..1199916 Mycobacterium tuberculosis KZN 1435 8164438 YP_003031010.1 CDS TBMG_01069 NC_012943.1 1199974 1200858 D signal peptidase I lepB 1199974..1200858 Mycobacterium tuberculosis KZN 1435 8164439 YP_003031011.1 CDS rnhB NC_012943.1 1200872 1201666 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1200872..1201666 Mycobacterium tuberculosis KZN 1435 8164440 YP_003031012.1 CDS TBMG_01071 NC_012943.1 1201720 1202025 D hypothetical protein 1201720..1202025 Mycobacterium tuberculosis KZN 1435 8164441 YP_003031013.1 CDS TBMG_01072 NC_012943.1 1202083 1204422 D formate dehydrogenase H fdhF 1202083..1204422 Mycobacterium tuberculosis KZN 1435 8164442 YP_003031014.1 CDS TBMG_01073 NC_012943.1 1204422 1205252 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 1204422..1205252 Mycobacterium tuberculosis KZN 1435 8164443 YP_003031015.1 CDS TBMG_01074 NC_012943.1 1205461 1205886 D hypothetical protein 1205461..1205886 Mycobacterium tuberculosis KZN 1435 8164444 YP_003031016.1 CDS TBMG_01075 NC_012943.1 1205886 1207397 D Mg chelatase 1205886..1207397 Mycobacterium tuberculosis KZN 1435 8164445 YP_003031017.1 CDS TBMG_01076 NC_012943.1 1207394 1208563 D hypothetical protein 1207394..1208563 Mycobacterium tuberculosis KZN 1435 8164446 YP_003031018.1 CDS TBMG_01077 NC_012943.1 1208596 1209447 D mycobactin utilization protein viuB 1208596..1209447 Mycobacterium tuberculosis KZN 1435 8164447 YP_003031019.1 CDS xerC NC_012943.1 1209538 1210434 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1209538..1210434 Mycobacterium tuberculosis KZN 1435 8164448 YP_003031020.1 CDS TBMG_01079 NC_012943.1 1210431 1211408 R oxidoreductase complement(1210431..1211408) Mycobacterium tuberculosis KZN 1435 8164449 YP_003031021.1 CDS TBMG_01080 NC_012943.1 1211820 1213034 D PPE family protein 1211820..1213034 Mycobacterium tuberculosis KZN 1435 8164450 YP_003031022.1 CDS TBMG_04013 NC_012943.1 1212813 1213562 R hypothetical protein complement(1212813..1213562) Mycobacterium tuberculosis KZN 1435 8164451 YP_003031023.1 CDS rpsB NC_012943.1 1213846 1214709 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1213846..1214709 Mycobacterium tuberculosis KZN 1435 8164452 YP_003031024.1 CDS tsf NC_012943.1 1214721 1215536 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1214721..1215536 Mycobacterium tuberculosis KZN 1435 8164453 YP_003031025.1 CDS TBMG_01083 NC_012943.1 1215543 1216964 D catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1215543..1216964 Mycobacterium tuberculosis KZN 1435 8164454 YP_003031026.1 CDS TBMG_01084 NC_012943.1 1216978 1217397 R transcriptional regulator complement(1216978..1217397) Mycobacterium tuberculosis KZN 1435 8164455 YP_003031027.1 CDS TBMG_01085 NC_012943.1 1217396 1218283 D resolvase 1217396..1218283 Mycobacterium tuberculosis KZN 1435 8164457 YP_003031028.1 CDS TBMG_01086 NC_012943.1 1218280 1219662 D transposase 1218280..1219662 Mycobacterium tuberculosis KZN 1435 8164456 YP_003031029.1 CDS TBMG_01087 NC_012943.1 1219677 1220435 R transcriptional regulator complement(1219677..1220435) Mycobacterium tuberculosis KZN 1435 8164458 YP_003031030.1 CDS pyrH NC_012943.1 1220670 1221455 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1220670..1221455 Mycobacterium tuberculosis KZN 1435 8164459 YP_003031031.1 CDS frr NC_012943.1 1221627 1222184 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1221627..1222184 Mycobacterium tuberculosis KZN 1435 8164460 YP_003031032.1 CDS TBMG_01090 NC_012943.1 1222207 1223127 D membrane phosphatidate cytidylyltransferase cdsA 1222207..1223127 Mycobacterium tuberculosis KZN 1435 8164461 YP_003031033.1 CDS TBMG_01091 NC_012943.1 1223150 1224244 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1223150..1224244 Mycobacterium tuberculosis KZN 1435 8164462 YP_003031034.1 CDS TBMG_01092 NC_012943.1 1224430 1224951 D soluble secreted antigen MPT53 precursor 1224430..1224951 Mycobacterium tuberculosis KZN 1435 8164463 YP_003031035.1 CDS TBMG_01093 NC_012943.1 1224956 1225819 D hypothetical protein 1224956..1225819 Mycobacterium tuberculosis KZN 1435 8164464 YP_003031036.1 CDS TBMG_01094 NC_012943.1 1225850 1226164 R hypothetical protein complement(1225850..1226164) Mycobacterium tuberculosis KZN 1435 8164465 YP_003031037.1 CDS TBMG_01095 NC_012943.1 1226216 1226806 R major secreted immunogenic protein MPT70 complement(1226216..1226806) Mycobacterium tuberculosis KZN 1435 8164466 YP_003031038.1 CDS TBMG_01096 NC_012943.1 1226893 1228980 R cytochrome C biogenesis protein dipZ complement(1226893..1228980) Mycobacterium tuberculosis KZN 1435 8164467 YP_003031039.1 CDS TBMG_01097 NC_012943.1 1229260 1229979 R cell surface lipoprotein MPT83 complement(1229260..1229979) Mycobacterium tuberculosis KZN 1435 8164468 YP_003031040.1 CDS TBMG_04014 NC_012943.1 1230002 1230445 R toxin complement(1230002..1230445) Mycobacterium tuberculosis KZN 1435 8164469 YP_003031041.1 CDS TBMG_04015 NC_012943.1 1230432 1230689 R antitoxin complement(1230432..1230689) Mycobacterium tuberculosis KZN 1435 8164470 YP_003031042.1 CDS TBMG_01099 NC_012943.1 1230768 1232057 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1230768..1232057 Mycobacterium tuberculosis KZN 1435 8164471 YP_003031043.1 CDS TBMG_01100 NC_012943.1 1232065 1233279 D hypothetical protein 1232065..1233279 Mycobacterium tuberculosis KZN 1435 8164472 YP_003031044.1 CDS ispG NC_012943.1 1233296 1234459 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1233296..1234459 Mycobacterium tuberculosis KZN 1435 8164473 YP_003031045.1 CDS TBMG_01102 NC_012943.1 1234515 1235369 D hypothetical protein 1234515..1235369 Mycobacterium tuberculosis KZN 1435 8164474 YP_003031046.1 CDS TBMG_01103 NC_012943.1 1235742 1236005 R toxin complement(1235742..1236005) Mycobacterium tuberculosis KZN 1435 8164475 YP_003031047.1 CDS TBMG_01104 NC_012943.1 1236009 1236290 R antitoxin complement(1236009..1236290) Mycobacterium tuberculosis KZN 1435 8164476 YP_003031048.1 CDS TBMG_01105 NC_012943.1 1236517 1238373 D penicillin-binding lipoprotein 1236517..1238373 Mycobacterium tuberculosis KZN 1435 8164477 YP_003031049.1 CDS TBMG_01106 NC_012943.1 1238455 1238835 R toxin complement(1238455..1238835) Mycobacterium tuberculosis KZN 1435 8164478 YP_003031050.1 CDS TBMG_01107 NC_012943.1 1238832 1239080 R antitoxin complement(1238832..1239080) Mycobacterium tuberculosis KZN 1435 8164479 YP_003031051.1 CDS TBMG_01108 NC_012943.1 1239184 1239768 D hypothetical protein 1239184..1239768 Mycobacterium tuberculosis KZN 1435 8164480 YP_003031052.1 CDS TBMG_01109 NC_012943.1 1239810 1240667 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase 1239810..1240667 Mycobacterium tuberculosis KZN 1435 8164481 YP_003031053.1 CDS TBMG_01110 NC_012943.1 1240827 1242200 D glutamine synthetase glnA4 1240827..1242200 Mycobacterium tuberculosis KZN 1435 8164482 YP_003031054.1 CDS TBMG_01111 NC_012943.1 1242181 1243107 D amidotransferase 1242181..1243107 Mycobacterium tuberculosis KZN 1435 8164483 YP_003031055.1 CDS TBMG_01112 NC_012943.1 1243104 1244471 D aldehyde dehydrogenase 1243104..1244471 Mycobacterium tuberculosis KZN 1435 8164484 YP_003031056.1 CDS TBMG_01113 NC_012943.1 1244468 1245244 D short chain dehydrogenase 1244468..1245244 Mycobacterium tuberculosis KZN 1435 8164485 YP_003031057.1 CDS TBMG_01114 NC_012943.1 1245400 1245615 R hypothetical protein complement(1245400..1245615) Mycobacterium tuberculosis KZN 1435 8164486 YP_003031058.1 CDS TBMG_01115 NC_012943.1 1245627 1245959 R hypothetical protein complement(1245627..1245959) Mycobacterium tuberculosis KZN 1435 8164487 YP_003031059.1 CDS TBMG_01116 NC_012943.1 1246025 1247143 R hypothetical protein complement(1246025..1247143) Mycobacterium tuberculosis KZN 1435 8164488 YP_003031060.1 CDS TBMG_01117 NC_012943.1 1247243 1248622 R catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; mycothione reductase complement(1247243..1248622) Mycobacterium tuberculosis KZN 1435 8164489 YP_003031061.1 CDS TBMG_01118 NC_012943.1 1248635 1249675 R hypothetical protein complement(1248635..1249675) Mycobacterium tuberculosis KZN 1435 8164490 YP_003031062.1 CDS TBMG_01119 NC_012943.1 1249712 1251703 R PE-PGRS family protein complement(1249712..1251703) Mycobacterium tuberculosis KZN 1435 8164491 YP_003031063.1 CDS TBMG_01120 NC_012943.1 1251766 1253247 D malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1251766..1253247 Mycobacterium tuberculosis KZN 1435 8164492 YP_003031064.1 CDS TBMG_01121 NC_012943.1 1253306 1253776 D hypothetical protein 1253306..1253776 Mycobacterium tuberculosis KZN 1435 8163377 YP_003031065.1 CDS TBMG_01122 NC_012943.1 1253773 1255662 D magnesium chelatase 1253773..1255662 Mycobacterium tuberculosis KZN 1435 8162744 YP_003031066.1 CDS TBMG_01123 NC_012943.1 1255683 1256306 D catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1255683..1256306 Mycobacterium tuberculosis KZN 1435 8162745 YP_003031067.1 CDS TBMG_01124 NC_012943.1 1256306 1257679 D responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1256306..1257679 Mycobacterium tuberculosis KZN 1435 8162746 YP_003031068.1 CDS TBMG_01125 NC_012943.1 1257956 1259173 D multifunctional siroheme synthase cysG 1257956..1259173 Mycobacterium tuberculosis KZN 1435 8162747 YP_003031069.1 CDS TBMG_01126 NC_012943.1 1259196 1260788 D membrane efflux protein efpA 1259196..1260788 Mycobacterium tuberculosis KZN 1435 8162748 YP_003031070.1 CDS TBMG_01127 NC_012943.1 1260877 1262625 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1260877..1262625 Mycobacterium tuberculosis KZN 1435 8162749 YP_003031071.1 CDS TBMG_01128 NC_012943.1 1262626 1263114 R hypothetical protein complement(1262626..1263114) Mycobacterium tuberculosis KZN 1435 8162750 YP_003031072.1 CDS TBMG_01129 NC_012943.1 1263111 1263656 R hypothetical protein complement(1263111..1263656) Mycobacterium tuberculosis KZN 1435 8162751 YP_003031073.1 CDS TBMG_01130 NC_012943.1 1263851 1264402 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1263851..1264402 Mycobacterium tuberculosis KZN 1435 8162752 YP_003031074.1 CDS nusA NC_012943.1 1264399 1265442 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1264399..1265442 Mycobacterium tuberculosis KZN 1435 8162753 YP_003031075.1 CDS TBMG_01132 NC_012943.1 1265569 1265868 D hypothetical protein 1265569..1265868 Mycobacterium tuberculosis KZN 1435 8162754 YP_003031076.1 CDS infB NC_012943.1 1265954 1268656 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1265954..1268656 Mycobacterium tuberculosis KZN 1435 8162755 YP_003031077.1 CDS rbfA NC_012943.1 1268656 1269207 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1268656..1269207 Mycobacterium tuberculosis KZN 1435 8162756 YP_003031078.1 CDS TBMG_01135 NC_012943.1 1269182 1270192 D hypothetical protein 1269182..1270192 Mycobacterium tuberculosis KZN 1435 8162757 YP_003031079.1 CDS TBMG_01136 NC_012943.1 1270199 1271518 D DNA-damage-inducible protein F dinF 1270199..1271518 Mycobacterium tuberculosis KZN 1435 8162758 YP_003031080.1 CDS TBMG_01137 NC_012943.1 1271605 1272516 D hypothetical protein 1271605..1272516 Mycobacterium tuberculosis KZN 1435 8162759 YP_003031081.1 CDS TBMG_01138 NC_012943.1 1272513 1273340 D hypothetical protein 1272513..1273340 Mycobacterium tuberculosis KZN 1435 8162760 YP_003031082.1 CDS TBMG_01139 NC_012943.1 1273343 1274653 D sn-glycerol-3-phosphate-binding lipoprotein ugpB 1273343..1274653 Mycobacterium tuberculosis KZN 1435 8162761 YP_003031083.1 CDS TBMG_01140 NC_012943.1 1274646 1275728 D sn-glycerol-3-phosphate transport ATP-binding protein ABC transporter ugpC 1274646..1275728 Mycobacterium tuberculosis KZN 1435 8162762 YP_003031084.1 CDS TBMG_01141 NC_012943.1 1275807 1276556 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1275807..1276556) Mycobacterium tuberculosis KZN 1435 8162763 YP_003031085.1 CDS TBMG_01142 NC_012943.1 1276603 1276818 D antitoxin 1276603..1276818 Mycobacterium tuberculosis KZN 1435 8162764 YP_003031086.1 CDS TBMG_01143 NC_012943.1 1276815 1277207 D toxin 1276815..1277207 Mycobacterium tuberculosis KZN 1435 8162765 YP_003031087.1 CDS TBMG_01144 NC_012943.1 1277228 1277497 D hypothetical protein 1277228..1277497 Mycobacterium tuberculosis KZN 1435 8162766 YP_003031088.1 CDS TBMG_01145 NC_012943.1 1277494 1278039 D hypothetical protein 1277494..1278039 Mycobacterium tuberculosis KZN 1435 8162767 YP_003031089.1 CDS TBMG_01146 NC_012943.1 1278329 1279231 D hypothetical protein 1278329..1279231 Mycobacterium tuberculosis KZN 1435 8162768 YP_003031090.1 CDS TBMG_01147 NC_012943.1 1279228 1280118 D hypothetical protein 1279228..1280118 Mycobacterium tuberculosis KZN 1435 8162769 YP_003031091.1 CDS TBMG_01148 NC_012943.1 1280195 1280935 D hypothetical protein 1280195..1280935 Mycobacterium tuberculosis KZN 1435 8162770 YP_003031092.1 CDS TBMG_01149 NC_012943.1 1281113 1282057 D hypothetical protein 1281113..1282057 Mycobacterium tuberculosis KZN 1435 8162771 YP_003031093.1 CDS TBMG_01150 NC_012943.1 1282054 1284492 D hypothetical protein 1282054..1284492 Mycobacterium tuberculosis KZN 1435 8162772 YP_003031094.1 CDS TBMG_01151 NC_012943.1 1284489 1284863 D hypothetical protein 1284489..1284863 Mycobacterium tuberculosis KZN 1435 8162773 YP_003031095.1 CDS TBMG_01152 NC_012943.1 1284873 1285583 D csm3 family CRISPR-associated ramp protein 1284873..1285583 Mycobacterium tuberculosis KZN 1435 8162774 YP_003031096.1 CDS TBMG_01153 NC_012943.1 1285564 1286472 D csm4 family CRISPR-associated ramp protein 1285564..1286472 Mycobacterium tuberculosis KZN 1435 8162775 YP_003031097.1 CDS TBMG_01154 NC_012943.1 1286469 1287596 D csm5 family CRISPR-associated ramp protein 1286469..1287596 Mycobacterium tuberculosis KZN 1435 8162776 YP_003031098.1 CDS TBMG_01155 NC_012943.1 1287593 1288840 D hypothetical protein 1287593..1288840 Mycobacterium tuberculosis KZN 1435 8162777 YP_003031099.1 CDS TBMG_01156 NC_012943.1 1288844 1289869 D hypothetical protein 1288844..1289869 Mycobacterium tuberculosis KZN 1435 8162778 YP_003031100.1 CDS TBMG_01157 NC_012943.1 1289870 1290211 D hypothetical protein 1289870..1290211 Mycobacterium tuberculosis KZN 1435 8162779 YP_003031101.1 CDS TBMG_01158 NC_012943.1 1291904 1292230 D transposase 1291904..1292230 Mycobacterium tuberculosis KZN 1435 8162780 YP_003031102.1 CDS TBMG_01159 NC_012943.1 1292281 1293165 D transposase 1292281..1293165 Mycobacterium tuberculosis KZN 1435 8162781 YP_003031103.1 CDS TBMG_01160 NC_012943.1 1294621 1295433 R hypothetical protein complement(1294621..1295433) Mycobacterium tuberculosis KZN 1435 8162782 YP_003031104.1 CDS TBMG_01161 NC_012943.1 1295430 1296839 R transposase complement(1295430..1296839) Mycobacterium tuberculosis KZN 1435 8162783 YP_003031105.1 CDS TBMG_01162 NC_012943.1 1296910 1297518 R hypothetical protein complement(1296910..1297518) Mycobacterium tuberculosis KZN 1435 8162784 YP_003031106.1 CDS TBMG_01163 NC_012943.1 1297518 1297916 D transposase 1297518..1297916 Mycobacterium tuberculosis KZN 1435 8162785 YP_003031107.1 CDS TBMG_01164 NC_012943.1 1297938 1298249 R hypothetical protein complement(1297938..1298249) Mycobacterium tuberculosis KZN 1435 8162786 YP_003031108.1 CDS TBMG_01165 NC_012943.1 1298354 1298623 R hypothetical protein complement(1298354..1298623) Mycobacterium tuberculosis KZN 1435 8162787 YP_003031109.1 CDS TBMG_01166 NC_012943.1 1298845 1299996 R hypothetical protein complement(1298845..1299996) Mycobacterium tuberculosis KZN 1435 8162788 YP_003031110.1 CDS TBMG_01167 NC_012943.1 1300198 1300389 R hypothetical protein complement(1300198..1300389) Mycobacterium tuberculosis KZN 1435 8162789 YP_003031111.1 CDS TBMG_01168 NC_012943.1 1300386 1300817 R hypothetical protein complement(1300386..1300817) Mycobacterium tuberculosis KZN 1435 8162790 YP_003031112.1 CDS TBMG_01169 NC_012943.1 1300863 1301228 R histone acetyltransferase complement(1300863..1301228) Mycobacterium tuberculosis KZN 1435 8162791 YP_003031113.1 CDS TBMG_01170 NC_012943.1 1301368 1301835 R hypothetical protein complement(1301368..1301835) Mycobacterium tuberculosis KZN 1435 8162792 YP_003031114.1 CDS TBMG_01171 NC_012943.1 1301834 1302877 D hypothetical protein 1301834..1302877 Mycobacterium tuberculosis KZN 1435 8162794 YP_003031115.1 CDS TBMG_01172 NC_012943.1 1302926 1303150 D transcriptional regulator 1302926..1303150 Mycobacterium tuberculosis KZN 1435 8162793 YP_003031116.1 CDS TBMG_01173 NC_012943.1 1303134 1303490 D hypothetical protein 1303134..1303490 Mycobacterium tuberculosis KZN 1435 8162795 YP_003031117.1 CDS TBMG_01174 NC_012943.1 1303592 1305241 R hydrolase complement(1303592..1305241) Mycobacterium tuberculosis KZN 1435 8162796 YP_003031118.1 CDS TBMG_01175 NC_012943.1 1305260 1305889 R hypothetical protein complement(1305260..1305889) Mycobacterium tuberculosis KZN 1435 8162797 YP_003031119.1 CDS TBMG_01176 NC_012943.1 1305999 1306346 D hypothetical protein 1305999..1306346 Mycobacterium tuberculosis KZN 1435 8162798 YP_003031120.1 CDS TBMG_01177 NC_012943.1 1306350 1308038 D hypothetical protein 1306350..1308038 Mycobacterium tuberculosis KZN 1435 8162799 YP_003031121.1 CDS TBMG_01178 NC_012943.1 1308038 1308601 D hypothetical protein 1308038..1308601 Mycobacterium tuberculosis KZN 1435 8162800 YP_003031122.1 CDS TBMG_01179 NC_012943.1 1308746 1309720 D hypothetical protein 1308746..1309720 Mycobacterium tuberculosis KZN 1435 8162801 YP_003031123.1 CDS TBMG_01180 NC_012943.1 1309717 1310400 D hypothetical protein 1309717..1310400 Mycobacterium tuberculosis KZN 1435 8162802 YP_003031124.1 CDS truB NC_012943.1 1310397 1311293 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1310397..1311293 Mycobacterium tuberculosis KZN 1435 8162803 YP_003031125.1 CDS TBMG_01182 NC_012943.1 1311495 1312076 D resolvase 1311495..1312076 Mycobacterium tuberculosis KZN 1435 8162804 YP_003031126.1 CDS TBMG_01183 NC_012943.1 1312076 1313455 D transposase 1312076..1313455 Mycobacterium tuberculosis KZN 1435 8162805 YP_003031127.1 CDS TBMG_01184 NC_012943.1 1313488 1314693 D lipid-transfer protein 1313488..1314693 Mycobacterium tuberculosis KZN 1435 8162806 YP_003031128.1 CDS TBMG_01185 NC_012943.1 1314719 1315951 D acyl-CoA dehydrogenase 1314719..1315951 Mycobacterium tuberculosis KZN 1435 8162807 YP_003031129.1 CDS TBMG_01186 NC_012943.1 1316012 1316698 R transcriptional repressor sirR complement(1316012..1316698) Mycobacterium tuberculosis KZN 1435 8162808 YP_003031130.1 CDS TBMG_01187 NC_012943.1 1316783 1318546 R hypothetical protein complement(1316783..1318546) Mycobacterium tuberculosis KZN 1435 8162809 YP_003031131.1 CDS TBMG_01188 NC_012943.1 1318757 1319752 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1318757..1319752 Mycobacterium tuberculosis KZN 1435 8162810 YP_003031132.1 CDS rpsO NC_012943.1 1319909 1320178 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1319909..1320178 Mycobacterium tuberculosis KZN 1435 8162811 YP_003031133.1 CDS TBMG_01190 NC_012943.1 1320191 1320706 D hypothetical protein 1320191..1320706 Mycobacterium tuberculosis KZN 1435 8162812 YP_003031134.1 CDS TBMG_01191 NC_012943.1 1321060 1323318 D polynucleotide phosphorylase 1321060..1323318 Mycobacterium tuberculosis KZN 1435 8162813 YP_003031135.1 CDS TBMG_01192 NC_012943.1 1323296 1324612 D zinc protease pepR 1323296..1324612 Mycobacterium tuberculosis KZN 1435 8162814 YP_003031136.1 CDS TBMG_01193 NC_012943.1 1324673 1325707 D hypothetical protein 1324673..1325707 Mycobacterium tuberculosis KZN 1435 8162815 YP_003031137.1 CDS TBMG_01194 NC_012943.1 1325722 1326837 R 40 kDa secreted L-alanine dehydrogenase ald complement(1325722..1326837) Mycobacterium tuberculosis KZN 1435 8162816 YP_003031138.1 CDS TBMG_01195 NC_012943.1 1326903 1327442 D transcriptional regulator, lrp/asnC-family 1326903..1327442 Mycobacterium tuberculosis KZN 1435 8162817 YP_003031139.1 CDS TBMG_01196 NC_012943.1 1327474 1327944 D hypothetical protein 1327474..1327944 Mycobacterium tuberculosis KZN 1435 8162818 YP_003031140.1 CDS TBMG_01197 NC_012943.1 1328102 1329172 D hypothetical protein 1328102..1329172 Mycobacterium tuberculosis KZN 1435 8162819 YP_003031141.1 CDS TBMG_01198 NC_012943.1 1329192 1330283 D oxidoreductase 1329192..1330283 Mycobacterium tuberculosis KZN 1435 8162820 YP_003031142.1 CDS TBMG_01199 NC_012943.1 1330496 1331380 R transposase complement(1330496..1331380) Mycobacterium tuberculosis KZN 1435 8162821 YP_003031143.1 CDS TBMG_01200 NC_012943.1 1331431 1331757 R transposase complement(1331431..1331757) Mycobacterium tuberculosis KZN 1435 8162822 YP_003031144.1 CDS TBMG_01201 NC_012943.1 1332260 1332664 D hypothetical protein 1332260..1332664 Mycobacterium tuberculosis KZN 1435 8162823 YP_003031145.1 CDS TBMG_01202 NC_012943.1 1332675 1333412 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1332675..1333412 Mycobacterium tuberculosis KZN 1435 8164404 YP_003031146.1 CDS TBMG_01203 NC_012943.1 1333424 1333897 D hypothetical protein 1333424..1333897 Mycobacterium tuberculosis KZN 1435 8164405 YP_003031147.1 CDS TBMG_01204 NC_012943.1 1333983 1334435 D hypothetical protein 1333983..1334435 Mycobacterium tuberculosis KZN 1435 8164406 YP_003031148.1 CDS TBMG_01205 NC_012943.1 1334499 1335707 D PPE family protein 1334499..1335707 Mycobacterium tuberculosis KZN 1435 8164604 YP_003031149.1 CDS TBMG_01206 NC_012943.1 1336031 1336858 D PE family protein 1336031..1336858 Mycobacterium tuberculosis KZN 1435 8164605 YP_003031150.1 CDS TBMG_01207 NC_012943.1 1336938 1338122 D PPE family protein 1336938..1338122 Mycobacterium tuberculosis KZN 1435 8164606 YP_003031151.1 CDS TBMG_04016 NC_012943.1 1338123 1338413 D hypothetical protein 1338123..1338413 Mycobacterium tuberculosis KZN 1435 8164607 YP_003031152.1 CDS TBMG_04017 NC_012943.1 1338296 1338649 D hypothetical protein 1338296..1338649 Mycobacterium tuberculosis KZN 1435 8164608 YP_003031153.1 CDS fabG NC_012943.1 1338646 1339428 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1338646..1339428 Mycobacterium tuberculosis KZN 1435 8164609 YP_003031154.1 CDS TBMG_01210 NC_012943.1 1339643 1340380 R hypothetical protein complement(1339643..1340380) Mycobacterium tuberculosis KZN 1435 8164610 YP_003031155.1 CDS thyA NC_012943.1 1340536 1341336 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1340536..1341336 Mycobacterium tuberculosis KZN 1435 8164611 YP_003031156.1 CDS TBMG_01212 NC_012943.1 1341401 1341886 D dihydrofolate reductase dfrA 1341401..1341886 Mycobacterium tuberculosis KZN 1435 8164612 YP_003031157.1 CDS TBMG_01213 NC_012943.1 1341960 1342379 D hypothetical protein 1341960..1342379 Mycobacterium tuberculosis KZN 1435 8164613 YP_003031158.1 CDS TBMG_01214 NC_012943.1 1342376 1343470 D type I restriction/modification system specificity determinant hsdS 1342376..1343470 Mycobacterium tuberculosis KZN 1435 8164614 YP_003031159.1 CDS TBMG_01215 NC_012943.1 1343480 1343749 D antitoxin 1343480..1343749 Mycobacterium tuberculosis KZN 1435 8164615 YP_003031160.1 CDS TBMG_01216 NC_012943.1 1343746 1344141 D toxin 1343746..1344141 Mycobacterium tuberculosis KZN 1435 8164616 YP_003031161.1 CDS TBMG_01217 NC_012943.1 1344167 1344433 D antitoxin 1344167..1344433 Mycobacterium tuberculosis KZN 1435 8164617 YP_003031162.1 CDS TBMG_01218 NC_012943.1 1344430 1344846 D toxin 1344430..1344846 Mycobacterium tuberculosis KZN 1435 8164618 YP_003031163.1 CDS TBMG_01219 NC_012943.1 1344933 1346555 D type I restriction/modification system DNA methylase hsdM 1344933..1346555 Mycobacterium tuberculosis KZN 1435 8164619 YP_003031164.1 CDS TBMG_01220 NC_012943.1 1346552 1346827 D type I restriction/modification system specificity determinant hsdS_1 1346552..1346827 Mycobacterium tuberculosis KZN 1435 8164620 YP_003031165.1 CDS thyX NC_012943.1 1347071 1347823 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1347071..1347823 Mycobacterium tuberculosis KZN 1435 8164621 YP_003031166.1 CDS TBMG_01222 NC_012943.1 1347883 1348794 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1347883..1348794 Mycobacterium tuberculosis KZN 1435 8164622 YP_003031167.1 CDS TBMG_01223 NC_012943.1 1348825 1350501 D hypothetical protein 1348825..1350501 Mycobacterium tuberculosis KZN 1435 8164623 YP_003031168.1 CDS TBMG_01224 NC_012943.1 1350488 1351378 R hypothetical protein complement(1350488..1351378) Mycobacterium tuberculosis KZN 1435 8164624 YP_003031169.1 CDS TBMG_01225 NC_012943.1 1351382 1352200 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1351382..1352200) Mycobacterium tuberculosis KZN 1435 8164625 YP_003031170.1 CDS TBMG_01226 NC_012943.1 1352197 1352511 R hypothetical protein complement(1352197..1352511) Mycobacterium tuberculosis KZN 1435 8164626 YP_003031171.1 CDS TBMG_01227 NC_012943.1 1352510 1355161 D hypothetical protein 1352510..1355161 Mycobacterium tuberculosis KZN 1435 8164628 YP_003031172.1 CDS TBMG_01228 NC_012943.1 1355230 1355754 R catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase complement(1355230..1355754) Mycobacterium tuberculosis KZN 1435 8164627 YP_003031173.1 CDS TBMG_01229 NC_012943.1 1355785 1356414 D phosphatidylglycerophosphate synthase pgsA3 1355785..1356414 Mycobacterium tuberculosis KZN 1435 8164629 YP_003031174.1 CDS TBMG_01230 NC_012943.1 1356485 1356823 D transcriptional regulator 1356485..1356823 Mycobacterium tuberculosis KZN 1435 8164630 YP_003031175.1 CDS TBMG_01231 NC_012943.1 1356953 1357765 D hypothetical protein 1356953..1357765 Mycobacterium tuberculosis KZN 1435 8164631 YP_003031176.1 CDS TBMG_01232 NC_012943.1 1357784 1358596 D hypothetical protein 1357784..1358596 Mycobacterium tuberculosis KZN 1435 8164632 YP_003031177.1 CDS TBMG_01233 NC_012943.1 1358668 1359501 D hypothetical protein 1358668..1359501 Mycobacterium tuberculosis KZN 1435 8164633 YP_003031178.1 CDS TBMG_01234 NC_012943.1 1359525 1361222 R PE-PGRS family protein complement(1359525..1361222) Mycobacterium tuberculosis KZN 1435 8164634 YP_003031179.1 CDS TBMG_01235 NC_012943.1 1361161 1361427 R hypothetical protein complement(1361161..1361427) Mycobacterium tuberculosis KZN 1435 8164635 YP_003031180.1 CDS TBMG_01236 NC_012943.1 1361334 1361783 R hypothetical protein complement(1361334..1361783) Mycobacterium tuberculosis KZN 1435 8164636 YP_003031181.1 CDS TBMG_01237 NC_012943.1 1361827 1362993 D hypothetical protein 1361827..1362993 Mycobacterium tuberculosis KZN 1435 8164637 YP_003031182.1 CDS TBMG_01238 NC_012943.1 1363224 1363397 R hypothetical protein complement(1363224..1363397) Mycobacterium tuberculosis KZN 1435 8164638 YP_003031183.1 CDS recA NC_012943.1 1363592 1365964 D these RecA proteins contain inteins; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; DNA recombination protein RecA 1363592..1365964 Mycobacterium tuberculosis KZN 1435 8164639 YP_003031184.1 CDS recX NC_012943.1 1365930 1366454 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1365930..1366454 Mycobacterium tuberculosis KZN 1435 8164640 YP_003031185.1 CDS TBMG_04018 NC_012943.1 1366464 1367456 D hypothetical protein 1366464..1367456 Mycobacterium tuberculosis KZN 1435 8164641 YP_003031186.1 CDS TBMG_01241 NC_012943.1 1367341 1368195 R hypothetical protein complement(1367341..1368195) Mycobacterium tuberculosis KZN 1435 8164642 YP_003031187.1 CDS TBMG_01242 NC_012943.1 1368393 1370030 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1368393..1370030 Mycobacterium tuberculosis KZN 1435 8164643 YP_003031188.1 CDS TBMG_01243 NC_012943.1 1370021 1370641 D hypothetical protein 1370021..1370641 Mycobacterium tuberculosis KZN 1435 8164644 YP_003031189.1 CDS TBMG_01244 NC_012943.1 1370638 1371990 R hypothetical protein complement(1370638..1371990) Mycobacterium tuberculosis KZN 1435 8164645 YP_003031190.1 CDS TBMG_01245 NC_012943.1 1371998 1372474 R hypothetical protein complement(1371998..1372474) Mycobacterium tuberculosis KZN 1435 8164646 YP_003031191.1 CDS TBMG_01246 NC_012943.1 1372541 1373446 D hypothetical protein 1372541..1373446 Mycobacterium tuberculosis KZN 1435 8164647 YP_003031192.1 CDS TBMG_01247 NC_012943.1 1373555 1374250 D hypothetical protein 1373555..1374250 Mycobacterium tuberculosis KZN 1435 8164648 YP_003031193.1 CDS miaA NC_012943.1 1374247 1375191 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1374247..1375191 Mycobacterium tuberculosis KZN 1435 8164649 YP_003031194.1 CDS dapF NC_012943.1 1375216 1376085 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1375216..1376085 Mycobacterium tuberculosis KZN 1435 8164650 YP_003031195.1 CDS TBMG_01250 NC_012943.1 1376102 1377589 D GTP-binding protein HflX 1376102..1377589 Mycobacterium tuberculosis KZN 1435 8164651 YP_003031196.1 CDS TBMG_01251 NC_012943.1 1377725 1378885 D acyl-CoA dehydrogenase 1377725..1378885 Mycobacterium tuberculosis KZN 1435 8164652 YP_003031197.1 CDS TBMG_01252 NC_012943.1 1378914 1380107 R hypothetical protein complement(1378914..1380107) Mycobacterium tuberculosis KZN 1435 8164653 YP_003031198.1 CDS TBMG_01253 NC_012943.1 1380397 1382496 D hypothetical protein 1380397..1382496 Mycobacterium tuberculosis KZN 1435 8164654 YP_003031199.1 CDS TBMG_01254 NC_012943.1 1382518 1383228 R Represses a number of genes involved in the response to DNA damage; LexA repressor complement(1382518..1383228) Mycobacterium tuberculosis KZN 1435 8164655 YP_003031200.1 CDS TBMG_01255 NC_012943.1 1383479 1383976 D hypothetical protein 1383479..1383976 Mycobacterium tuberculosis KZN 1435 8164656 YP_003031201.1 CDS nrdR NC_012943.1 1384139 1384603 D transcriptional regulator NrdR 1384139..1384603 Mycobacterium tuberculosis KZN 1435 8164657 YP_003031202.1 CDS TBMG_01257 NC_012943.1 1384655 1385149 D hypothetical protein 1384655..1385149 Mycobacterium tuberculosis KZN 1435 8164658 YP_003031203.1 CDS TBMG_01258 NC_012943.1 1385158 1385844 R hypothetical protein complement(1385158..1385844) Mycobacterium tuberculosis KZN 1435 8164659 YP_003031204.1 CDS TBMG_01259 NC_012943.1 1385893 1386918 R hydrolase complement(1385893..1386918) Mycobacterium tuberculosis KZN 1435 8164660 YP_003031205.1 CDS TBMG_01260 NC_012943.1 1386977 1387951 R hypothetical protein complement(1386977..1387951) Mycobacterium tuberculosis KZN 1435 8164661 YP_003031206.1 CDS TBMG_01261 NC_012943.1 1388169 1389584 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(1388169..1389584) Mycobacterium tuberculosis KZN 1435 8164662 YP_003031207.1 CDS TBMG_01262 NC_012943.1 1389679 1390746 D hypothetical protein 1389679..1390746 Mycobacterium tuberculosis KZN 1435 8164663 YP_003031208.1 CDS TBMG_01263 NC_012943.1 1390759 1391451 R iron-dependent repressor and activator ideR complement(1390759..1391451) Mycobacterium tuberculosis KZN 1435 8164664 YP_003031209.1 CDS TBMG_01264 NC_012943.1 1391584 1392621 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase; RNA polymerase sigma factor SigB complement(1391584..1392621) Mycobacterium tuberculosis KZN 1435 8164665 YP_003031210.1 CDS TBMG_01265 NC_012943.1 1392731 1393177 R hypothetical protein complement(1392731..1393177) Mycobacterium tuberculosis KZN 1435 8164666 YP_003031211.1 CDS TBMG_01266 NC_012943.1 1393181 1393468 D hypothetical protein 1393181..1393468 Mycobacterium tuberculosis KZN 1435 8164667 YP_003031212.1 CDS TBMG_01267 NC_012943.1 1393469 1394443 R hypothetical protein complement(1393469..1394443) Mycobacterium tuberculosis KZN 1435 8164668 YP_003031213.1 CDS TBMG_04019 NC_012943.1 1394505 1394693 R hypothetical protein complement(1394505..1394693) Mycobacterium tuberculosis KZN 1435 8164669 YP_003031214.1 CDS TBMG_01268 NC_012943.1 1394813 1395202 D hypothetical protein 1394813..1395202 Mycobacterium tuberculosis KZN 1435 8164670 YP_003031215.1 CDS TBMG_01269 NC_012943.1 1395130 1395558 R hypothetical protein complement(1395130..1395558) Mycobacterium tuberculosis KZN 1435 8164671 YP_003031216.1 CDS TBMG_01270 NC_012943.1 1395595 1397181 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor complement(1395595..1397181) Mycobacterium tuberculosis KZN 1435 8164672 YP_003031217.1 CDS TBMG_01271 NC_012943.1 1397361 1398158 R polyphosphate glucokinase ppgK complement(1397361..1398158) Mycobacterium tuberculosis KZN 1435 8164673 YP_003031218.1 CDS TBMG_01272 NC_012943.1 1398281 1399153 D extragenic suppressor protein suhB 1398281..1399153 Mycobacterium tuberculosis KZN 1435 8164674 YP_003031219.1 CDS TBMG_01273 NC_012943.1 1399163 1399813 R hypothetical protein complement(1399163..1399813) Mycobacterium tuberculosis KZN 1435 8164675 YP_003031220.1 CDS TBMG_01274 NC_012943.1 1400051 1400353 D hypothetical protein 1400051..1400353 Mycobacterium tuberculosis KZN 1435 8164676 YP_003031221.1 CDS TBMG_01275 NC_012943.1 1400358 1400843 R hypothetical protein complement(1400358..1400843) Mycobacterium tuberculosis KZN 1435 8164677 YP_003031222.1 CDS dut NC_012943.1 1400869 1401333 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1400869..1401333 Mycobacterium tuberculosis KZN 1435 8164678 YP_003031223.1 CDS TBMG_01277 NC_012943.1 1401408 1402187 D hypothetical protein 1401408..1402187 Mycobacterium tuberculosis KZN 1435 8164679 YP_003031224.1 CDS TBMG_01278 NC_012943.1 1402393 1403100 R hypothetical protein complement(1402393..1403100) Mycobacterium tuberculosis KZN 1435 8164680 YP_003031225.1 CDS TBMG_01279 NC_012943.1 1403144 1403617 D hypothetical protein 1403144..1403617 Mycobacterium tuberculosis KZN 1435 8164681 YP_003031226.1 CDS TBMG_01280 NC_012943.1 1403648 1404319 D hypothetical protein 1403648..1404319 Mycobacterium tuberculosis KZN 1435 8164682 YP_003031227.1 CDS TBMG_01281 NC_012943.1 1404330 1404992 R trk system potassium uptake protein ceoC complement(1404330..1404992) Mycobacterium tuberculosis KZN 1435 8164683 YP_003031228.1 CDS TBMG_01282 NC_012943.1 1404989 1405672 R trk system potassium uptake protein ceoB complement(1404989..1405672) Mycobacterium tuberculosis KZN 1435 8164407 YP_003031229.1 CDS TBMG_01283 NC_012943.1 1405807 1407780 D hypothetical protein 1405807..1407780 Mycobacterium tuberculosis KZN 1435 8162334 YP_003031230.1 CDS TBMG_01284 NC_012943.1 1407954 1409171 D hypothetical protein 1407954..1409171 Mycobacterium tuberculosis KZN 1435 8162335 YP_003031231.1 CDS TBMG_01285 NC_012943.1 1409366 1410271 D antibiotic-transport ATP-binding protein ABC transporter 1409366..1410271 Mycobacterium tuberculosis KZN 1435 8162336 YP_003031232.1 CDS TBMG_01286 NC_012943.1 1410268 1410981 D hypothetical protein 1410268..1410981 Mycobacterium tuberculosis KZN 1435 8162337 YP_003031233.1 CDS TBMG_01287 NC_012943.1 1410978 1411736 D hypothetical protein 1410978..1411736 Mycobacterium tuberculosis KZN 1435 8162338 YP_003031234.1 CDS TBMG_01288 NC_012943.1 1411747 1413033 R hypothetical protein complement(1411747..1413033) Mycobacterium tuberculosis KZN 1435 8162339 YP_003031235.1 CDS TBMG_01289 NC_012943.1 1413113 1414402 R hypothetical protein complement(1413113..1414402) Mycobacterium tuberculosis KZN 1435 8162340 YP_003031236.1 CDS TBMG_01290 NC_012943.1 1414407 1414904 R hypothetical protein complement(1414407..1414904) Mycobacterium tuberculosis KZN 1435 8162341 YP_003031237.1 CDS TBMG_01291 NC_012943.1 1415048 1416964 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1415048..1416964 Mycobacterium tuberculosis KZN 1435 8162342 YP_003031238.1 CDS TBMG_01292 NC_012943.1 1416961 1418277 R hypothetical protein complement(1416961..1418277) Mycobacterium tuberculosis KZN 1435 8162343 YP_003031239.1 CDS TBMG_01293 NC_012943.1 1418279 1418911 R hypothetical protein complement(1418279..1418911) Mycobacterium tuberculosis KZN 1435 8162344 YP_003031240.1 CDS TBMG_01294 NC_012943.1 1419173 1420003 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1419173..1420003) Mycobacterium tuberculosis KZN 1435 8162345 YP_003031241.1 CDS hemE NC_012943.1 1420056 1421129 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1420056..1421129 Mycobacterium tuberculosis KZN 1435 8162346 YP_003031242.1 CDS TBMG_01296 NC_012943.1 1421126 1422484 D catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX; protoporphyrinogen oxidase 1421126..1422484 Mycobacterium tuberculosis KZN 1435 8162347 YP_003031243.1 CDS TBMG_01297 NC_012943.1 1422490 1423185 D hypothetical protein 1422490..1423185 Mycobacterium tuberculosis KZN 1435 8162348 YP_003031244.1 CDS TBMG_01298 NC_012943.1 1423182 1423934 D hypothetical protein 1423182..1423934 Mycobacterium tuberculosis KZN 1435 8162349 YP_003031245.1 CDS TBMG_01299 NC_012943.1 1424002 1424412 R methionine-R-sulfoxide reductase complement(1424002..1424412) Mycobacterium tuberculosis KZN 1435 8162350 YP_003031246.1 CDS TBMG_01300 NC_012943.1 1424581 1425882 R hypothetical protein complement(1424581..1425882) Mycobacterium tuberculosis KZN 1435 8162351 YP_003031247.1 CDS TBMG_01301 NC_012943.1 1425905 1427491 R secreted protease complement(1425905..1427491) Mycobacterium tuberculosis KZN 1435 8162352 YP_003031248.1 CDS TBMG_01302 NC_012943.1 1427558 1428334 R hypothetical protein complement(1427558..1428334) Mycobacterium tuberculosis KZN 1435 8162353 YP_003031249.1 CDS TBMG_01303 NC_012943.1 1428333 1429442 D hypothetical protein 1428333..1429442 Mycobacterium tuberculosis KZN 1435 8162355 YP_003031250.1 CDS TBMG_01304 NC_012943.1 1429420 1429890 R hypothetical protein complement(1429420..1429890) Mycobacterium tuberculosis KZN 1435 8162354 YP_003031251.1 CDS TBMG_01305 NC_012943.1 1429919 1430485 R hypothetical protein complement(1429919..1430485) Mycobacterium tuberculosis KZN 1435 8162356 YP_003031252.1 CDS TBMG_01306 NC_012943.1 1430519 1431277 R ATP-dependent protease ATP-binding subunit clpC2 complement(1430519..1431277) Mycobacterium tuberculosis KZN 1435 8162357 YP_003031253.1 CDS TBMG_01307 NC_012943.1 1431299 1432165 R transposase complement(1431299..1432165) Mycobacterium tuberculosis KZN 1435 8162358 YP_003031254.1 CDS TBMG_01308 NC_012943.1 1432193 1432474 R hypothetical protein complement(1432193..1432474) Mycobacterium tuberculosis KZN 1435 8162359 YP_003031255.1 CDS TBMG_01309 NC_012943.1 1432822 1433076 R hypothetical protein complement(1432822..1433076) Mycobacterium tuberculosis KZN 1435 8162360 YP_003031256.1 CDS TBMG_01310 NC_012943.1 1433087 1433320 R hypothetical protein complement(1433087..1433320) Mycobacterium tuberculosis KZN 1435 8162361 YP_003031257.1 CDS TBMG_01311 NC_012943.1 1433419 1433691 R hypothetical protein complement(1433419..1433691) Mycobacterium tuberculosis KZN 1435 8162362 YP_003031258.1 CDS TBMG_01312 NC_012943.1 1433597 1433986 D hypothetical protein 1433597..1433986 Mycobacterium tuberculosis KZN 1435 8162364 YP_003031259.1 CDS TBMG_01313 NC_012943.1 1433983 1434210 D hypothetical protein 1433983..1434210 Mycobacterium tuberculosis KZN 1435 8162363 YP_003031260.1 CDS TBMG_01314 NC_012943.1 1434355 1435482 D phiRv2 phage integrase 1434355..1435482 Mycobacterium tuberculosis KZN 1435 8162365 YP_003031261.1 CDS TBMG_01315 NC_012943.1 1435482 1435847 D phiRv2 phage protein 1435482..1435847 Mycobacterium tuberculosis KZN 1435 8162366 YP_003031262.1 CDS TBMG_01316 NC_012943.1 1435864 1436124 D phiRv2 phage protein 1435864..1436124 Mycobacterium tuberculosis KZN 1435 8162367 YP_003031263.1 CDS TBMG_01317 NC_012943.1 1436121 1436513 D phiRv2 phage protein 1436121..1436513 Mycobacterium tuberculosis KZN 1435 8162368 YP_003031264.1 CDS TBMG_01318 NC_012943.1 1436515 1437942 D phiRv2 phage protein 1436515..1437942 Mycobacterium tuberculosis KZN 1435 8162369 YP_003031265.1 CDS TBMG_01319 NC_012943.1 1437939 1438184 D phiRv2 phage protein 1437939..1438184 Mycobacterium tuberculosis KZN 1435 8162370 YP_003031266.1 CDS TBMG_01320 NC_012943.1 1438171 1438587 D phiRv2 phage protein 1438171..1438587 Mycobacterium tuberculosis KZN 1435 8162371 YP_003031267.1 CDS TBMG_01321 NC_012943.1 1438619 1439245 D phiRv2 phage protein 1438619..1439245 Mycobacterium tuberculosis KZN 1435 8162372 YP_003031268.1 CDS TBMG_01322 NC_012943.1 1439398 1439931 D phiRv2 phage protease 1439398..1439931 Mycobacterium tuberculosis KZN 1435 8162373 YP_003031269.1 CDS TBMG_01323 NC_012943.1 1439939 1441378 D phiRv2 phage protein 1439939..1441378 Mycobacterium tuberculosis KZN 1435 8162374 YP_003031270.1 CDS TBMG_01324 NC_012943.1 1441788 1442252 R hypothetical protein complement(1441788..1442252) Mycobacterium tuberculosis KZN 1435 8162375 YP_003031271.1 CDS TBMG_01325 NC_012943.1 1442266 1443264 R integrase complement(1442266..1443264) Mycobacterium tuberculosis KZN 1435 8162376 YP_003031272.1 CDS TBMG_01326 NC_012943.1 1443261 1443692 R hypothetical protein complement(1443261..1443692) Mycobacterium tuberculosis KZN 1435 8162377 YP_003031273.1 CDS TBMG_01327 NC_012943.1 1444983 1445405 R hypothetical protein complement(1444983..1445405) Mycobacterium tuberculosis KZN 1435 8162382 YP_003031274.1 CDS TBMG_01328 NC_012943.1 1445409 1446905 R hypothetical protein complement(1445409..1446905) Mycobacterium tuberculosis KZN 1435 8162383 YP_003031275.1 CDS TBMG_01329 NC_012943.1 1446902 1447282 R transcriptional regulator, arsR-family complement(1446902..1447282) Mycobacterium tuberculosis KZN 1435 8162384 YP_003031276.1 CDS TBMG_01330 NC_012943.1 1447418 1447876 R cadmium inducible protein cadI complement(1447418..1447876) Mycobacterium tuberculosis KZN 1435 8162385 YP_003031277.1 CDS TBMG_01331 NC_012943.1 1447978 1448337 D transcriptional regulator, arsR-family 1447978..1448337 Mycobacterium tuberculosis KZN 1435 8162386 YP_003031278.1 CDS TBMG_01332 NC_012943.1 1448457 1448789 D hypothetical protein 1448457..1448789 Mycobacterium tuberculosis KZN 1435 8162387 YP_003031279.1 CDS TBMG_01333 NC_012943.1 1448964 1449410 R hypothetical protein complement(1448964..1449410) Mycobacterium tuberculosis KZN 1435 8162388 YP_003031280.1 CDS TBMG_01334 NC_012943.1 1449573 1450229 R hypothetical protein complement(1449573..1450229) Mycobacterium tuberculosis KZN 1435 8162389 YP_003031281.1 CDS TBMG_01335 NC_012943.1 1450425 1451102 R hypothetical protein complement(1450425..1451102) Mycobacterium tuberculosis KZN 1435 8162390 YP_003031282.1 CDS TBMG_04020 NC_012943.1 1451103 1451345 R hypothetical protein complement(1451103..1451345) Mycobacterium tuberculosis KZN 1435 8162391 YP_003031283.1 CDS TBMG_01336 NC_012943.1 1451344 1453710 D PE-PGRS family protein 1451344..1453710 Mycobacterium tuberculosis KZN 1435 8162393 YP_003031284.1 CDS TBMG_01337 NC_012943.1 1453714 1453968 D hypothetical protein 1453714..1453968 Mycobacterium tuberculosis KZN 1435 8162392 YP_003031285.1 CDS TBMG_01338 NC_012943.1 1453995 1454480 D hypothetical protein 1453995..1454480 Mycobacterium tuberculosis KZN 1435 8162394 YP_003031286.1 CDS TBMG_01339 NC_012943.1 1454625 1454906 D hypothetical protein 1454625..1454906 Mycobacterium tuberculosis KZN 1435 8162395 YP_003031287.1 CDS TBMG_01340 NC_012943.1 1454945 1456243 R hypothetical protein complement(1454945..1456243) Mycobacterium tuberculosis KZN 1435 8162396 YP_003031288.1 CDS TBMG_01341 NC_012943.1 1456383 1456922 R hypothetical protein complement(1456383..1456922) Mycobacterium tuberculosis KZN 1435 8162397 YP_003031289.1 CDS TBMG_01342 NC_012943.1 1456924 1458048 R hypothetical protein complement(1456924..1458048) Mycobacterium tuberculosis KZN 1435 8162398 YP_003031290.1 CDS TBMG_01343 NC_012943.1 1458395 1458757 R hypothetical protein complement(1458395..1458757) Mycobacterium tuberculosis KZN 1435 8162399 YP_003031291.1 CDS TBMG_01344 NC_012943.1 1459067 1460308 D hypothetical protein 1459067..1460308 Mycobacterium tuberculosis KZN 1435 8162400 YP_003031292.1 CDS TBMG_01345 NC_012943.1 1460822 1461253 D hypothetical protein 1460822..1461253 Mycobacterium tuberculosis KZN 1435 8162401 YP_003031293.1 CDS TBMG_01346 NC_012943.1 1461312 1462493 D hypothetical protein 1461312..1462493 Mycobacterium tuberculosis KZN 1435 8162402 YP_003031294.1 CDS TBMG_01347 NC_012943.1 1462508 1463326 D hypothetical protein 1462508..1463326 Mycobacterium tuberculosis KZN 1435 8162403 YP_003031295.1 CDS TBMG_01348 NC_012943.1 1463329 1464222 R hypothetical protein complement(1463329..1464222) Mycobacterium tuberculosis KZN 1435 8162404 YP_003031296.1 CDS TBMG_01349 NC_012943.1 1464358 1465179 R methyltransferase/methylase complement(1464358..1465179) Mycobacterium tuberculosis KZN 1435 8162405 YP_003031297.1 CDS TBMG_01350 NC_012943.1 1465257 1465931 D transcriptional regulator 1465257..1465931 Mycobacterium tuberculosis KZN 1435 8162406 YP_003031298.1 CDS TBMG_01351 NC_012943.1 1465928 1466353 D hypothetical protein 1465928..1466353 Mycobacterium tuberculosis KZN 1435 8162407 YP_003031299.1 CDS TBMG_01352 NC_012943.1 1466366 1466719 D hypothetical protein 1466366..1466719 Mycobacterium tuberculosis KZN 1435 8162408 YP_003031300.1 CDS TBMG_01353 NC_012943.1 1466704 1467432 R hypothetical protein complement(1466704..1467432) Mycobacterium tuberculosis KZN 1435 8162409 YP_003031301.1 CDS TBMG_01354 NC_012943.1 1467528 1467968 D hypothetical protein 1467528..1467968 Mycobacterium tuberculosis KZN 1435 8162410 YP_003031302.1 CDS TBMG_01355 NC_012943.1 1467985 1468485 R hypothetical protein complement(1467985..1468485) Mycobacterium tuberculosis KZN 1435 8162411 YP_003031303.1 CDS TBMG_01356 NC_012943.1 1468785 1470215 D PE-PGRS family protein 1468785..1470215 Mycobacterium tuberculosis KZN 1435 8164408 YP_003031304.1 CDS thrS NC_012943.1 1470548 1472626 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1470548..1472626 Mycobacterium tuberculosis KZN 1435 8164409 YP_003031305.1 CDS TBMG_01358 NC_012943.1 1472619 1473206 D hypothetical protein 1472619..1473206 Mycobacterium tuberculosis KZN 1435 8163542 YP_003031306.1 CDS TBMG_01359 NC_012943.1 1473203 1473856 D phosphatidylinositol synthase pgsA1 1473203..1473856 Mycobacterium tuberculosis KZN 1435 8163543 YP_003031307.1 CDS TBMG_01360 NC_012943.1 1473853 1474803 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1473853..1474803 Mycobacterium tuberculosis KZN 1435 8163544 YP_003031308.1 CDS TBMG_01361 NC_012943.1 1474814 1475950 D alpha-mannosyltransferase pimA 1474814..1475950 Mycobacterium tuberculosis KZN 1435 8163545 YP_003031309.1 CDS TBMG_01362 NC_012943.1 1475950 1477005 D hypothetical protein 1475950..1477005 Mycobacterium tuberculosis KZN 1435 8163546 YP_003031310.1 CDS TBMG_01363 NC_012943.1 1477027 1478769 R PPE family protein complement(1477027..1478769) Mycobacterium tuberculosis KZN 1435 8163547 YP_003031311.1 CDS TBMG_01364 NC_012943.1 1478943 1479617 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1478943..1479617) Mycobacterium tuberculosis KZN 1435 8163548 YP_003031312.1 CDS TBMG_01365 NC_012943.1 1479745 1480644 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1479745..1480644 Mycobacterium tuberculosis KZN 1435 8163549 YP_003031313.1 CDS TBMG_01366 NC_012943.1 1480673 1481518 D acyl-CoA thioesterase 1480673..1481518 Mycobacterium tuberculosis KZN 1435 8163550 YP_003031314.1 CDS TBMG_01367 NC_012943.1 1481526 1482122 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1481526..1482122 Mycobacterium tuberculosis KZN 1435 8163551 YP_003031315.1 CDS TBMG_01368 NC_012943.1 1482255 1483010 D hypothetical protein 1482255..1483010 Mycobacterium tuberculosis KZN 1435 8163552 YP_003031316.1 CDS TBMG_01369 NC_012943.1 1483031 1483471 R toxin complement(1483031..1483471) Mycobacterium tuberculosis KZN 1435 8163553 YP_003031317.1 CDS TBMG_01370 NC_012943.1 1483458 1483745 R antitoxin complement(1483458..1483745) Mycobacterium tuberculosis KZN 1435 8163554 YP_003031318.1 CDS TBMG_01371 NC_012943.1 1483856 1485427 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(1483856..1485427) Mycobacterium tuberculosis KZN 1435 8163555 YP_003031319.1 CDS TBMG_01372 NC_012943.1 1485424 1485882 R hypothetical protein complement(1485424..1485882) Mycobacterium tuberculosis KZN 1435 8163556 YP_003031320.1 CDS TBMG_01373 NC_012943.1 1485907 1486338 R hypothetical protein complement(1485907..1486338) Mycobacterium tuberculosis KZN 1435 8163557 YP_003031321.1 CDS TBMG_01374 NC_012943.1 1486335 1486829 R hypothetical protein complement(1486335..1486829) Mycobacterium tuberculosis KZN 1435 8163558 YP_003031322.1 CDS TBMG_01375 NC_012943.1 1486840 1487460 R hypothetical protein complement(1486840..1487460) Mycobacterium tuberculosis KZN 1435 8163559 YP_003031323.1 CDS TBMG_01376 NC_012943.1 1487677 1488081 R toxin complement(1487677..1488081) Mycobacterium tuberculosis KZN 1435 8163560 YP_003031324.1 CDS TBMG_01377 NC_012943.1 1488078 1488323 R antitoxin complement(1488078..1488323) Mycobacterium tuberculosis KZN 1435 8163561 YP_003031325.1 CDS ruvC NC_012943.1 1488432 1488998 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1488432..1488998 Mycobacterium tuberculosis KZN 1435 8163562 YP_003031326.1 CDS ruvA NC_012943.1 1488995 1489585 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1488995..1489585 Mycobacterium tuberculosis KZN 1435 8163563 YP_003031327.1 CDS ruvB NC_012943.1 1489582 1490616 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1489582..1490616 Mycobacterium tuberculosis KZN 1435 8163564 YP_003031328.1 CDS TBMG_01381 NC_012943.1 1490633 1492294 R PE-PGRS family protein complement(1490633..1492294) Mycobacterium tuberculosis KZN 1435 8163565 YP_003031329.1 CDS TBMG_01382 NC_012943.1 1492438 1495944 R fatty-acid-CoA ligase fadD9 complement(1492438..1495944) Mycobacterium tuberculosis KZN 1435 8163566 YP_003031330.1 CDS TBMG_01383 NC_012943.1 1496106 1497455 R catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase complement(1496106..1497455) Mycobacterium tuberculosis KZN 1435 8163567 YP_003031331.1 CDS TBMG_01384 NC_012943.1 1497384 1497593 D hypothetical protein 1497384..1497593 Mycobacterium tuberculosis KZN 1435 8163569 YP_003031332.1 CDS yajC NC_012943.1 1497622 1497969 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1497622..1497969 Mycobacterium tuberculosis KZN 1435 8163568 YP_003031333.1 CDS secD NC_012943.1 1498079 1499800 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1498079..1499800 Mycobacterium tuberculosis KZN 1435 8163570 YP_003031334.1 CDS secF NC_012943.1 1499804 1501132 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1499804..1501132 Mycobacterium tuberculosis KZN 1435 8163571 YP_003031335.1 CDS TBMG_01388 NC_012943.1 1501138 1502811 D lipoprotein 1501138..1502811 Mycobacterium tuberculosis KZN 1435 8163572 YP_003031336.1 CDS TBMG_01389 NC_012943.1 1502915 1503586 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1502915..1503586 Mycobacterium tuberculosis KZN 1435 8163573 YP_003031337.1 CDS TBMG_01390 NC_012943.1 1503608 1505989 D GTP pyrophosphokinase 1503608..1505989 Mycobacterium tuberculosis KZN 1435 8163574 YP_003031338.1 CDS TBMG_01391 NC_012943.1 1506075 1507001 R peptidyl-prolyl-cis-trans-isomerase B ppiB complement(1506075..1507001) Mycobacterium tuberculosis KZN 1435 8163575 YP_003031339.1 CDS TBMG_01392 NC_012943.1 1506986 1507726 D glyoxalase II 1506986..1507726 Mycobacterium tuberculosis KZN 1435 8163577 YP_003031340.1 CDS hisS NC_012943.1 1507723 1508994 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1507723..1508994 Mycobacterium tuberculosis KZN 1435 8163576 YP_003031341.1 CDS TBMG_01394 NC_012943.1 1509274 1510176 R catalyzes the cleavage of carbon-halogen bonds in aliphatic compounds forming a primary alcohol and a halide; haloalkane dehalogenase complement(1509274..1510176) Mycobacterium tuberculosis KZN 1435 8163578 YP_003031342.1 CDS TBMG_01395 NC_012943.1 1510284 1511306 D hypothetical protein 1510284..1511306 Mycobacterium tuberculosis KZN 1435 8163579 YP_003031343.1 CDS TBMG_01396 NC_012943.1 1511308 1512897 R hypothetical protein complement(1511308..1512897) Mycobacterium tuberculosis KZN 1435 8163580 YP_003031344.1 CDS TBMG_01397 NC_012943.1 1513125 1513589 D hypothetical protein 1513125..1513589 Mycobacterium tuberculosis KZN 1435 8163581 YP_003031345.1 CDS TBMG_01398 NC_012943.1 1513595 1514476 R hypothetical protein complement(1513595..1514476) Mycobacterium tuberculosis KZN 1435 8163582 YP_003031346.1 CDS TBMG_01399 NC_012943.1 1514506 1515009 R hypothetical protein complement(1514506..1515009) Mycobacterium tuberculosis KZN 1435 8163583 YP_003031347.1 CDS TBMG_01400 NC_012943.1 1515032 1515859 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(1515032..1515859) Mycobacterium tuberculosis KZN 1435 8163584 YP_003031348.1 CDS aspS NC_012943.1 1516012 1517802 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1516012..1517802 Mycobacterium tuberculosis KZN 1435 8163585 YP_003031349.1 CDS TBMG_01402 NC_012943.1 1517855 1518922 D hypothetical protein 1517855..1518922 Mycobacterium tuberculosis KZN 1435 8163586 YP_003031350.1 CDS TBMG_01403 NC_012943.1 1518914 1519303 R hypothetical protein complement(1518914..1519303) Mycobacterium tuberculosis KZN 1435 8163587 YP_003031351.1 CDS TBMG_01404 NC_012943.1 1519407 1520351 D hypothetical protein 1519407..1520351 Mycobacterium tuberculosis KZN 1435 8163588 YP_003031352.1 CDS TBMG_01405 NC_012943.1 1520344 1521369 D hypothetical protein 1520344..1521369 Mycobacterium tuberculosis KZN 1435 8163589 YP_003031353.1 CDS TBMG_01406 NC_012943.1 1521366 1524020 R hypothetical protein complement(1521366..1524020) Mycobacterium tuberculosis KZN 1435 8163590 YP_003031354.1 CDS TBMG_01407 NC_012943.1 1524020 1527442 R hypothetical protein complement(1524020..1527442) Mycobacterium tuberculosis KZN 1435 8163591 YP_003031355.1 CDS TBMG_01408 NC_012943.1 1527453 1529204 R hypothetical protein complement(1527453..1529204) Mycobacterium tuberculosis KZN 1435 8163592 YP_003031356.1 CDS TBMG_01409 NC_012943.1 1529481 1530473 R glutamine-transport ATP-binding protein ABC transporter glnQ complement(1529481..1530473) Mycobacterium tuberculosis KZN 1435 8163593 YP_003031357.1 CDS TBMG_01410 NC_012943.1 1530476 1531525 R hypothetical protein complement(1530476..1531525) Mycobacterium tuberculosis KZN 1435 8163594 YP_003031358.1 CDS TBMG_01411 NC_012943.1 1531668 1532405 R hypothetical protein complement(1531668..1532405) Mycobacterium tuberculosis KZN 1435 8163595 YP_003031359.1 CDS TBMG_04021 NC_012943.1 1532526 1532849 D hypothetical protein 1532526..1532849 Mycobacterium tuberculosis KZN 1435 8163596 YP_003031360.1 CDS TBMG_01412 NC_012943.1 1532762 1533739 R hypothetical protein complement(1532762..1533739) Mycobacterium tuberculosis KZN 1435 8163597 YP_003031361.1 CDS TBMG_01413 NC_012943.1 1533885 1535243 D recombination factor protein RarA 1533885..1535243 Mycobacterium tuberculosis KZN 1435 8163598 YP_003031362.1 CDS TBMG_01414 NC_012943.1 1535273 1535983 R hypothetical protein complement(1535273..1535983) Mycobacterium tuberculosis KZN 1435 8163599 YP_003031363.1 CDS TBMG_01415 NC_012943.1 1536068 1536742 R hypothetical protein complement(1536068..1536742) Mycobacterium tuberculosis KZN 1435 8163600 YP_003031364.1 CDS TBMG_01416 NC_012943.1 1536837 1537238 D hypothetical protein 1536837..1537238 Mycobacterium tuberculosis KZN 1435 8163601 YP_003031365.1 CDS alaS NC_012943.1 1537329 1540043 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1537329..1540043 Mycobacterium tuberculosis KZN 1435 8163602 YP_003031366.1 CDS TBMG_01418 NC_012943.1 1540044 1540556 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1540044..1540556 Mycobacterium tuberculosis KZN 1435 8163603 YP_003031367.1 CDS TBMG_01419 NC_012943.1 1540549 1541802 D hypothetical protein 1540549..1541802 Mycobacterium tuberculosis KZN 1435 8163604 YP_003031368.1 CDS aroE NC_012943.1 1541799 1542608 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1541799..1542608 Mycobacterium tuberculosis KZN 1435 8163605 YP_003031369.1 CDS TBMG_01421 NC_012943.1 1542620 1543039 D hypothetical protein 1542620..1543039 Mycobacterium tuberculosis KZN 1435 8163606 YP_003031370.1 CDS TBMG_01422 NC_012943.1 1543450 1543695 D antitoxin 1543450..1543695 Mycobacterium tuberculosis KZN 1435 8163607 YP_003031371.1 CDS TBMG_01423 NC_012943.1 1543692 1544087 D toxin 1543692..1544087 Mycobacterium tuberculosis KZN 1435 8163608 YP_003031372.1 CDS TBMG_01424 NC_012943.1 1544187 1544561 D hypothetical protein 1544187..1544561 Mycobacterium tuberculosis KZN 1435 8163609 YP_003031373.1 CDS TBMG_01425 NC_012943.1 1544577 1544954 R toxin complement(1544577..1544954) Mycobacterium tuberculosis KZN 1435 8163610 YP_003031374.1 CDS TBMG_01426 NC_012943.1 1544951 1545208 R antitoxin complement(1544951..1545208) Mycobacterium tuberculosis KZN 1435 8163611 YP_003031375.1 CDS TBMG_01427 NC_012943.1 1545247 1545660 R toxin complement(1545247..1545660) Mycobacterium tuberculosis KZN 1435 8163612 YP_003031376.1 CDS TBMG_01428 NC_012943.1 1545753 1546031 R antitoxin complement(1545753..1546031) Mycobacterium tuberculosis KZN 1435 8163613 YP_003031377.1 CDS TBMG_01429 NC_012943.1 1546028 1546690 R hypothetical protein complement(1546028..1546690) Mycobacterium tuberculosis KZN 1435 8163614 YP_003031378.1 CDS TBMG_01430 NC_012943.1 1546687 1547346 R hypothetical protein complement(1546687..1547346) Mycobacterium tuberculosis KZN 1435 8163615 YP_003031379.1 CDS TBMG_01431 NC_012943.1 1547473 1548684 R hypothetical protein complement(1547473..1548684) Mycobacterium tuberculosis KZN 1435 8163616 YP_003031380.1 CDS TBMG_01432 NC_012943.1 1548980 1549387 R hypothetical protein complement(1548980..1549387) Mycobacterium tuberculosis KZN 1435 8163617 YP_003031381.1 CDS TBMG_01433 NC_012943.1 1549402 1550607 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1549402..1550607 Mycobacterium tuberculosis KZN 1435 8163618 YP_003031382.1 CDS aroK NC_012943.1 1550611 1551141 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1550611..1551141 Mycobacterium tuberculosis KZN 1435 8163619 YP_003031383.1 CDS aroB NC_012943.1 1551138 1552226 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1551138..1552226 Mycobacterium tuberculosis KZN 1435 8163620 YP_003031384.1 CDS TBMG_01436 NC_012943.1 1552223 1552666 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1552223..1552666 Mycobacterium tuberculosis KZN 1435 8163621 YP_003031385.1 CDS TBMG_01437 NC_012943.1 1552670 1553368 R hypothetical protein complement(1552670..1553368) Mycobacterium tuberculosis KZN 1435 8164410 YP_003031386.1 CDS TBMG_01438 NC_012943.1 1553396 1554514 D cytoplasmic peptidase pepQ 1553396..1554514 Mycobacterium tuberculosis KZN 1435 8164411 YP_003031387.1 CDS TBMG_01439 NC_012943.1 1554524 1555087 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1554524..1555087 Mycobacterium tuberculosis KZN 1435 8162493 YP_003031388.1 CDS nusB NC_012943.1 1555090 1555560 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1555090..1555560 Mycobacterium tuberculosis KZN 1435 8163209 YP_003031389.1 CDS TBMG_01441 NC_012943.1 1555557 1555961 D hypothetical protein 1555557..1555961 Mycobacterium tuberculosis KZN 1435 8163210 YP_003031390.1 CDS TBMG_01442 NC_012943.1 1556033 1558876 D amino acid decarboxylase 1556033..1558876 Mycobacterium tuberculosis KZN 1435 8163211 YP_003031391.1 CDS TBMG_04022 NC_012943.1 1558907 1559131 D antitoxin 1558907..1559131 Mycobacterium tuberculosis KZN 1435 8163212 YP_003031392.1 CDS TBMG_01443 NC_012943.1 1559128 1559547 D toxin 1559128..1559547 Mycobacterium tuberculosis KZN 1435 8163213 YP_003031393.1 CDS TBMG_01444 NC_012943.1 1559548 1560558 R hypothetical protein complement(1559548..1560558) Mycobacterium tuberculosis KZN 1435 8163214 YP_003031394.1 CDS TBMG_01445 NC_012943.1 1561143 1562063 D restriction system protein mrr 1561143..1562063 Mycobacterium tuberculosis KZN 1435 8163215 YP_003031395.1 CDS TBMG_01446 NC_012943.1 1562098 1562499 R toxin complement(1562098..1562499) Mycobacterium tuberculosis KZN 1435 8163216 YP_003031396.1 CDS TBMG_04023 NC_012943.1 1562496 1562723 R antitoxin complement(1562496..1562723) Mycobacterium tuberculosis KZN 1435 8163217 YP_003031397.1 CDS TBMG_01447 NC_012943.1 1563240 1563962 D hypothetical protein 1563240..1563962 Mycobacterium tuberculosis KZN 1435 8163218 YP_003031398.1 CDS TBMG_01448 NC_012943.1 1564482 1573691 D fatty-acid synthase fas 1564482..1573691 Mycobacterium tuberculosis KZN 1435 8163219 YP_003031399.1 CDS acpS NC_012943.1 1573884 1574276 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1573884..1574276 Mycobacterium tuberculosis KZN 1435 8163220 YP_003031400.1 CDS TBMG_01450 NC_012943.1 1574273 1575685 D hypothetical protein 1574273..1575685 Mycobacterium tuberculosis KZN 1435 8163221 YP_003031401.1 CDS TBMG_01451 NC_012943.1 1575657 1576130 R bacterioferritin comigratory protein bcp complement(1575657..1576130) Mycobacterium tuberculosis KZN 1435 8163222 YP_003031402.1 CDS TBMG_01452 NC_012943.1 1576199 1576426 D hypothetical protein 1576199..1576426 Mycobacterium tuberculosis KZN 1435 8163223 YP_003031403.1 CDS TBMG_01453 NC_012943.1 1576551 1578029 R PE family protein complement(1576551..1578029) Mycobacterium tuberculosis KZN 1435 8163224 YP_003031404.1 CDS TBMG_01454 NC_012943.1 1578479 1579705 D hypothetical protein 1578479..1579705 Mycobacterium tuberculosis KZN 1435 8163226 YP_003031405.1 CDS TBMG_01455 NC_012943.1 1580301 1581104 D hypothetical protein 1580301..1581104 Mycobacterium tuberculosis KZN 1435 8163227 YP_003031406.1 CDS TBMG_01456 NC_012943.1 1581223 1582470 D hypothetical protein 1581223..1582470 Mycobacterium tuberculosis KZN 1435 8163228 YP_003031407.1 CDS TBMG_01457 NC_012943.1 1582476 1582937 D hypothetical protein 1582476..1582937 Mycobacterium tuberculosis KZN 1435 8163229 YP_003031408.1 CDS TBMG_01458 NC_012943.1 1583231 1583653 R hypothetical protein complement(1583231..1583653) Mycobacterium tuberculosis KZN 1435 8163230 YP_003031409.1 CDS TBMG_01459 NC_012943.1 1583948 1585258 D transposase 1583948..1585258 Mycobacterium tuberculosis KZN 1435 8163231 YP_003031410.1 CDS TBMG_01460 NC_012943.1 1586010 1586657 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(1586010..1586657) Mycobacterium tuberculosis KZN 1435 8163233 YP_003031411.1 CDS TBMG_01461 NC_012943.1 1586725 1588326 D hypothetical protein 1586725..1588326 Mycobacterium tuberculosis KZN 1435 8163234 YP_003031412.1 CDS TBMG_01462 NC_012943.1 1588330 1589136 R short-chain type dehydrogenase/reductase complement(1588330..1589136) Mycobacterium tuberculosis KZN 1435 8163235 YP_003031413.1 CDS TBMG_01463 NC_012943.1 1589212 1590558 D hypothetical protein 1589212..1590558 Mycobacterium tuberculosis KZN 1435 8163236 YP_003031414.1 CDS TBMG_01464 NC_012943.1 1590555 1591376 R hypothetical protein complement(1590555..1591376) Mycobacterium tuberculosis KZN 1435 8163237 YP_003031415.1 CDS TBMG_01465 NC_012943.1 1591455 1592102 R TetR family transcriptional regulator complement(1591455..1592102) Mycobacterium tuberculosis KZN 1435 8163238 YP_003031416.1 CDS TBMG_01466 NC_012943.1 1592218 1593861 D AMP-binding protein 1592218..1593861 Mycobacterium tuberculosis KZN 1435 8163239 YP_003031417.1 CDS TBMG_01467 NC_012943.1 1593944 1594690 D succinyl-CoA:3-ketoacid-coenzyme A transferase alpha subunit scoA 1593944..1594690 Mycobacterium tuberculosis KZN 1435 8163240 YP_003031418.1 CDS TBMG_01468 NC_012943.1 1594687 1595343 D succinyl-CoA:3-ketoacid-coenzyme A transferase beta subunit scoB 1594687..1595343 Mycobacterium tuberculosis KZN 1435 8163241 YP_003031419.1 CDS TBMG_01469 NC_012943.1 1595340 1596929 D acetyl-/propionyl-CoA carboxylase beta subunit accD1 1595340..1596929 Mycobacterium tuberculosis KZN 1435 8163242 YP_003031420.1 CDS TBMG_01470 NC_012943.1 1596934 1598898 D acetyl-/propionyl-CoA carboxylase alpha subunit accA1 1596934..1598898 Mycobacterium tuberculosis KZN 1435 8163243 YP_003031421.1 CDS TBMG_01471 NC_012943.1 1598903 1600087 D acyl-CoA dehydrogenase 1598903..1600087 Mycobacterium tuberculosis KZN 1435 8163244 YP_003031422.1 CDS TBMG_01472 NC_012943.1 1600084 1600641 D oxidase regulatory-related protein 1600084..1600641 Mycobacterium tuberculosis KZN 1435 8163245 YP_003031423.1 CDS TBMG_01473 NC_012943.1 1600638 1601459 D citrate (pro-3s)-lyase beta subunit citE 1600638..1601459 Mycobacterium tuberculosis KZN 1435 8163246 YP_003031424.1 CDS TBMG_01474 NC_012943.1 1601718 1602821 D pyruvate dehydrogenase E1 component alpha subunit pdhA 1601718..1602821 Mycobacterium tuberculosis KZN 1435 8163247 YP_003031425.1 CDS TBMG_01475 NC_012943.1 1602832 1603878 D pyruvate dehydrogenase E1 component beta subunit pdhB 1602832..1603878 Mycobacterium tuberculosis KZN 1435 8163248 YP_003031426.1 CDS TBMG_01476 NC_012943.1 1603875 1605056 D branched-chain alpha-keto acid dehydrogenase subunit E2 1603875..1605056 Mycobacterium tuberculosis KZN 1435 8163249 YP_003031427.1 CDS TBMG_01477 NC_012943.1 1605079 1605504 R toxin complement(1605079..1605504) Mycobacterium tuberculosis KZN 1435 8163250 YP_003031428.1 CDS TBMG_01478 NC_012943.1 1605510 1605731 R antitoxin complement(1605510..1605731) Mycobacterium tuberculosis KZN 1435 8163251 YP_003031429.1 CDS TBMG_01479 NC_012943.1 1605986 1606870 R transposase complement(1605986..1606870) Mycobacterium tuberculosis KZN 1435 8163252 YP_003031430.1 CDS TBMG_01480 NC_012943.1 1606921 1607247 R transposase complement(1606921..1607247) Mycobacterium tuberculosis KZN 1435 8163253 YP_003031431.1 CDS TBMG_01481 NC_012943.1 1607884 1608507 R hypothetical protein complement(1607884..1608507) Mycobacterium tuberculosis KZN 1435 8163254 YP_003031432.1 CDS TBMG_01482 NC_012943.1 1608643 1608849 D hypothetical protein 1608643..1608849 Mycobacterium tuberculosis KZN 1435 8163255 YP_003031433.1 CDS TBMG_04024 NC_012943.1 1608936 1613786 D hypothetical protein 1608936..1613786 Mycobacterium tuberculosis KZN 1435 8163256 YP_003031434.1 CDS TBMG_01485 NC_012943.1 1613895 1614194 D hypothetical protein 1613895..1614194 Mycobacterium tuberculosis KZN 1435 8163257 YP_003031435.1 CDS TBMG_01486 NC_012943.1 1614160 1617573 D transcriptional regulator, luxR-family 1614160..1617573 Mycobacterium tuberculosis KZN 1435 8163258 YP_003031436.1 CDS TBMG_01487 NC_012943.1 1617655 1619739 D PE-PGRS family protein 1617655..1619739 Mycobacterium tuberculosis KZN 1435 8163259 YP_003031437.1 CDS TBMG_01488 NC_012943.1 1619920 1620690 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1619920..1620690) Mycobacterium tuberculosis KZN 1435 8163260 YP_003031438.1 CDS TBMG_01489 NC_012943.1 1621040 1622317 D carboxylesterase lipQ 1621040..1622317 Mycobacterium tuberculosis KZN 1435 8163262 YP_003031439.1 CDS TBMG_01490 NC_012943.1 1622540 1624021 D hypothetical protein 1622540..1624021 Mycobacterium tuberculosis KZN 1435 8163263 YP_003031440.1 CDS TBMG_01491 NC_012943.1 1624018 1625760 D bifunctionnal phospholipid biosynthesis enzyme plsC 1624018..1625760 Mycobacterium tuberculosis KZN 1435 8163264 YP_003031441.1 CDS TBMG_01492 NC_012943.1 1625757 1628126 D PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 1625757..1628126 Mycobacterium tuberculosis KZN 1435 8163265 YP_003031442.1 CDS TBMG_01493 NC_012943.1 1628142 1628465 D hypothetical protein 1628142..1628465 Mycobacterium tuberculosis KZN 1435 8163266 YP_003031443.1 CDS TBMG_01494 NC_012943.1 1628521 1628778 R hypothetical protein complement(1628521..1628778) Mycobacterium tuberculosis KZN 1435 8163267 YP_003031444.1 CDS TBMG_01495 NC_012943.1 1629053 1629559 D hypothetical protein 1629053..1629559 Mycobacterium tuberculosis KZN 1435 8163268 YP_003031445.1 CDS TBMG_01496 NC_012943.1 1629640 1631316 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1629640..1631316 Mycobacterium tuberculosis KZN 1435 8163269 YP_003031446.1 CDS TBMG_01497 NC_012943.1 1631420 1636294 D NAD-dependent glutamate dehydrogenase gdh 1631420..1636294 Mycobacterium tuberculosis KZN 1435 8163270 YP_003031447.1 CDS TBMG_01498 NC_012943.1 1636291 1636707 D hypothetical protein 1636291..1636707 Mycobacterium tuberculosis KZN 1435 8163271 YP_003031448.1 CDS TBMG_01499 NC_012943.1 1636713 1637363 D hypothetical protein 1636713..1637363 Mycobacterium tuberculosis KZN 1435 8163272 YP_003031449.1 CDS TBMG_01500 NC_012943.1 1637395 1638111 R hypothetical protein complement(1637395..1638111) Mycobacterium tuberculosis KZN 1435 8163273 YP_003031450.1 CDS TBMG_01501 NC_012943.1 1638114 1638407 R hypothetical protein complement(1638114..1638407) Mycobacterium tuberculosis KZN 1435 8163274 YP_003031451.1 CDS TBMG_01502 NC_012943.1 1638475 1640115 R alpha-glucosidase complement(1638475..1640115) Mycobacterium tuberculosis KZN 1435 8163275 YP_003031452.1 CDS TBMG_01503 NC_012943.1 1640115 1640519 R oxygen-binding protein globin glbO complement(1640115..1640519) Mycobacterium tuberculosis KZN 1435 8163276 YP_003031453.1 CDS TBMG_01504 NC_012943.1 1640644 1641312 D hypothetical protein 1640644..1641312 Mycobacterium tuberculosis KZN 1435 8163277 YP_003031454.1 CDS TBMG_01505 NC_012943.1 1641532 1642035 D hypothetical protein 1641532..1642035 Mycobacterium tuberculosis KZN 1435 8163278 YP_003031455.1 CDS TBMG_01506 NC_012943.1 1642108 1644693 R aminopeptidase complement(1642108..1644693) Mycobacterium tuberculosis KZN 1435 8163279 YP_003031456.1 CDS TBMG_01507 NC_012943.1 1644795 1645418 D hypothetical protein 1644795..1645418 Mycobacterium tuberculosis KZN 1435 8163280 YP_003031457.1 CDS TBMG_01508 NC_012943.1 1645520 1646008 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 1645520..1646008 Mycobacterium tuberculosis KZN 1435 8163281 YP_003031458.1 CDS TBMG_01509 NC_012943.1 1646014 1646820 D DNA glycosylase 1646014..1646820 Mycobacterium tuberculosis KZN 1435 8163282 YP_003031459.1 CDS TBMG_01510 NC_012943.1 1646840 1648024 R esterase/lipase lipP complement(1646840..1648024) Mycobacterium tuberculosis KZN 1435 8163283 YP_003031460.1 CDS tig NC_012943.1 1648388 1649788 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1648388..1649788 Mycobacterium tuberculosis KZN 1435 8163286 YP_003031461.1 CDS clpP NC_012943.1 1649905 1650507 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1649905..1650507 Mycobacterium tuberculosis KZN 1435 8163287 YP_003031462.1 CDS TBMG_01513 NC_012943.1 1650504 1651148 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1650504..1651148 Mycobacterium tuberculosis KZN 1435 8163288 YP_003031463.1 CDS TBMG_01514 NC_012943.1 1651299 1652915 R membrane transporter complement(1651299..1652915) Mycobacterium tuberculosis KZN 1435 8163289 YP_003031464.1 CDS mmuM NC_012943.1 1652992 1653900 R converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase complement(1652992..1653900) Mycobacterium tuberculosis KZN 1435 8163379 YP_003031465.1 CDS clpX NC_012943.1 1654191 1655471 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1654191..1655471 Mycobacterium tuberculosis KZN 1435 8163380 YP_003031466.1 CDS TBMG_01517 NC_012943.1 1655487 1656743 D membrane transporter 1655487..1656743 Mycobacterium tuberculosis KZN 1435 8163381 YP_003031467.1 CDS TBMG_01518 NC_012943.1 1656960 1658936 D oxidoreductase alpha subunit 1656960..1658936 Mycobacterium tuberculosis KZN 1435 8163382 YP_003031468.1 CDS TBMG_01519 NC_012943.1 1658933 1660054 D catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1658933..1660054 Mycobacterium tuberculosis KZN 1435 8163383 YP_003031469.1 CDS TBMG_01520 NC_012943.1 1660056 1660661 D MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 1660056..1660661 Mycobacterium tuberculosis KZN 1435 8163384 YP_003031470.1 CDS TBMG_01521 NC_012943.1 1661019 1661417 R hypothetical protein complement(1661019..1661417) Mycobacterium tuberculosis KZN 1435 8163385 YP_003031471.1 CDS TBMG_01522 NC_012943.1 1661451 1662017 D resuscitation-promoting factor rpfE 1661451..1662017 Mycobacterium tuberculosis KZN 1435 8163386 YP_003031472.1 CDS TBMG_01523 NC_012943.1 1662107 1663366 D saccharopine dehydrogenase 1662107..1663366 Mycobacterium tuberculosis KZN 1435 8163387 YP_003031473.1 CDS valS NC_012943.1 1663424 1666084 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1663424..1666084 Mycobacterium tuberculosis KZN 1435 8163388 YP_003031474.1 CDS TBMG_01525 NC_012943.1 1666081 1667544 D folylpolyglutamate synthase folC 1666081..1667544 Mycobacterium tuberculosis KZN 1435 8163389 YP_003031475.1 CDS TBMG_01526 NC_012943.1 1667541 1667912 D hypothetical protein 1667541..1667912 Mycobacterium tuberculosis KZN 1435 8163390 YP_003031476.1 CDS ndk NC_012943.1 1667955 1668365 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1667955..1668365 Mycobacterium tuberculosis KZN 1435 8163391 YP_003031477.1 CDS TBMG_01528 NC_012943.1 1668695 1671556 D ribonuclease E rne 1668695..1671556 Mycobacterium tuberculosis KZN 1435 8163392 YP_003031478.1 CDS TBMG_01529 NC_012943.1 1671495 1672970 R hypothetical protein complement(1671495..1672970) Mycobacterium tuberculosis KZN 1435 8163393 YP_003031479.1 CDS rplU NC_012943.1 1673318 1673632 D 50S ribosomal protein L21 1673318..1673632 Mycobacterium tuberculosis KZN 1435 8163394 YP_003031480.1 CDS rpmA NC_012943.1 1673647 1673907 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1673647..1673907 Mycobacterium tuberculosis KZN 1435 8163395 YP_003031481.1 CDS obgE NC_012943.1 1673993 1675432 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1673993..1675432 Mycobacterium tuberculosis KZN 1435 8163396 YP_003031482.1 CDS TBMG_01533 NC_012943.1 1675432 1676562 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1675432..1676562 Mycobacterium tuberculosis KZN 1435 8163397 YP_003031483.1 CDS nadE NC_012943.1 1676671 1678887 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1676671..1678887 Mycobacterium tuberculosis KZN 1435 8163398 YP_003031484.1 CDS TBMG_01535 NC_012943.1 1678884 1679303 R hypothetical protein complement(1678884..1679303) Mycobacterium tuberculosis KZN 1435 8163399 YP_003031485.1 CDS TBMG_01536 NC_012943.1 1679535 1680449 R ribokinase rbsK complement(1679535..1680449) Mycobacterium tuberculosis KZN 1435 8163400 YP_003031486.1 CDS TBMG_01537 NC_012943.1 1680930 1683122 D cyclase 1680930..1683122 Mycobacterium tuberculosis KZN 1435 8163401 YP_003031487.1 CDS TBMG_01538 NC_012943.1 1683119 1684564 D hypothetical protein 1683119..1684564 Mycobacterium tuberculosis KZN 1435 8163402 YP_003031488.1 CDS TBMG_01539 NC_012943.1 1684545 1684835 D hypothetical protein 1684545..1684835 Mycobacterium tuberculosis KZN 1435 8163403 YP_003031489.1 CDS TBMG_01540 NC_012943.1 1684832 1685242 D hypothetical protein 1684832..1685242 Mycobacterium tuberculosis KZN 1435 8163404 YP_003031490.1 CDS TBMG_01541 NC_012943.1 1685413 1685712 D PE family protein 1685413..1685712 Mycobacterium tuberculosis KZN 1435 8163405 YP_003031491.1 CDS TBMG_01542 NC_012943.1 1685759 1686343 D PPE family protein 1685759..1686343 Mycobacterium tuberculosis KZN 1435 8163406 YP_003031492.1 CDS TBMG_01543 NC_012943.1 1686340 1686873 R alkyl hydroperoxide reductase complement(1686340..1686873) Mycobacterium tuberculosis KZN 1435 8163407 YP_003031493.1 CDS TBMG_01544 NC_012943.1 1686899 1687486 R alkyl hydroperoxide reductase complement(1686899..1687486) Mycobacterium tuberculosis KZN 1435 8163408 YP_003031494.1 CDS TBMG_01545 NC_012943.1 1687619 1687813 D OxyR protein 1687619..1687813 Mycobacterium tuberculosis KZN 1435 8163409 YP_003031495.1 CDS TBMG_01546 NC_012943.1 1687818 1688084 D hydrogen peroxide-inducible genes activator 1687818..1688084 Mycobacterium tuberculosis KZN 1435 8163410 YP_003031496.1 CDS proA NC_012943.1 1688202 1689449 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1688202..1689449 Mycobacterium tuberculosis KZN 1435 8163411 YP_003031497.1 CDS TBMG_01548 NC_012943.1 1689496 1690371 D hypothetical protein 1689496..1690371 Mycobacterium tuberculosis KZN 1435 8163412 YP_003031498.1 CDS TBMG_01549 NC_012943.1 1690371 1691813 D hypothetical protein 1690371..1691813 Mycobacterium tuberculosis KZN 1435 8163413 YP_003031499.1 CDS TBMG_01550 NC_012943.1 1691902 1692903 D transposase 1691902..1692903 Mycobacterium tuberculosis KZN 1435 8163414 YP_003031500.1 CDS TBMG_01551 NC_012943.1 1693036 1694082 R hypothetical protein complement(1693036..1694082) Mycobacterium tuberculosis KZN 1435 8163415 YP_003031501.1 CDS TBMG_01552 NC_012943.1 1694324 1694596 R hypothetical protein complement(1694324..1694596) Mycobacterium tuberculosis KZN 1435 8163416 YP_003031502.1 CDS nadD NC_012943.1 1694871 1695506 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1694871..1695506 Mycobacterium tuberculosis KZN 1435 8163417 YP_003031503.1 CDS TBMG_01554 NC_012943.1 1695503 1695883 D hypothetical protein 1695503..1695883 Mycobacterium tuberculosis KZN 1435 8163418 YP_003031504.1 CDS TBMG_01555 NC_012943.1 1695880 1696551 D phosphoglycerate mutase 1695880..1696551 Mycobacterium tuberculosis KZN 1435 8163419 YP_003031505.1 CDS TBMG_01556 NC_012943.1 1696541 1697284 D hypothetical protein 1696541..1697284 Mycobacterium tuberculosis KZN 1435 8163420 YP_003031506.1 CDS TBMG_01557 NC_012943.1 1697374 1698207 D hypothetical protein 1697374..1698207 Mycobacterium tuberculosis KZN 1435 8163421 YP_003031507.1 CDS TBMG_01558 NC_012943.1 1698329 1699555 D hypothetical protein 1698329..1699555 Mycobacterium tuberculosis KZN 1435 8163422 YP_003031508.1 CDS TBMG_01559 NC_012943.1 1699895 1700791 D hypothetical protein 1699895..1700791 Mycobacterium tuberculosis KZN 1435 8163423 YP_003031509.1 CDS TBMG_01560 NC_012943.1 1700797 1702350 D hypothetical protein 1700797..1702350 Mycobacterium tuberculosis KZN 1435 8163424 YP_003031510.1 CDS TBMG_01561 NC_012943.1 1702363 1703331 D hypothetical protein 1702363..1703331 Mycobacterium tuberculosis KZN 1435 8163425 YP_003031511.1 CDS rpsT NC_012943.1 1703347 1703607 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(1703347..1703607) Mycobacterium tuberculosis KZN 1435 8163426 YP_003031512.1 CDS TBMG_01563 NC_012943.1 1703717 1705372 D hypothetical protein 1703717..1705372 Mycobacterium tuberculosis KZN 1435 8163427 YP_003031513.1 CDS TBMG_01564 NC_012943.1 1705372 1706349 D hypothetical protein 1705372..1706349 Mycobacterium tuberculosis KZN 1435 8163428 YP_003031514.1 CDS TBMG_01565 NC_012943.1 1706349 1707188 D hypothetical protein 1706349..1707188 Mycobacterium tuberculosis KZN 1435 8163429 YP_003031515.1 CDS TBMG_01566 NC_012943.1 1706946 1707950 R PE family protein complement(1706946..1707950) Mycobacterium tuberculosis KZN 1435 8163430 YP_003031516.1 CDS TBMG_01567 NC_012943.1 1708164 1709006 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(1708164..1709006) Mycobacterium tuberculosis KZN 1435 8163431 YP_003031517.1 CDS TBMG_01568 NC_012943.1 1709266 1709694 D hypothetical protein 1709266..1709694 Mycobacterium tuberculosis KZN 1435 8163432 YP_003031518.1 CDS TBMG_01569 NC_012943.1 1709865 1710467 R hypothetical protein complement(1709865..1710467) Mycobacterium tuberculosis KZN 1435 8163433 YP_003031519.1 CDS TBMG_01570 NC_012943.1 1710455 1712416 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1710455..1712416 Mycobacterium tuberculosis KZN 1435 8163435 YP_003031520.1 CDS TBMG_01571 NC_012943.1 1712413 1713168 D hypothetical protein 1712413..1713168 Mycobacterium tuberculosis KZN 1435 8163434 YP_003031521.1 CDS TBMG_01572 NC_012943.1 1713246 1715174 R hypothetical protein complement(1713246..1715174) Mycobacterium tuberculosis KZN 1435 8163436 YP_003031522.1 CDS TBMG_01573 NC_012943.1 1715458 1715661 D hypothetical protein 1715458..1715661 Mycobacterium tuberculosis KZN 1435 8163437 YP_003031523.1 CDS TBMG_01574 NC_012943.1 1715646 1715975 R hypothetical protein complement(1715646..1715975) Mycobacterium tuberculosis KZN 1435 8163438 YP_003031524.1 CDS TBMG_01575 NC_012943.1 1715989 1717059 D sulfate-binding lipoprotein subI 1715989..1717059 Mycobacterium tuberculosis KZN 1435 8163439 YP_003031525.1 CDS TBMG_01576 NC_012943.1 1717056 1717907 D hypothetical protein 1717056..1717907 Mycobacterium tuberculosis KZN 1435 8163440 YP_003031526.1 CDS TBMG_01577 NC_012943.1 1717904 1718722 D hypothetical protein 1717904..1718722 Mycobacterium tuberculosis KZN 1435 8163441 YP_003031527.1 CDS TBMG_01578 NC_012943.1 1718739 1719794 D sulfate-transport ATP-binding protein ABC transporter cysA1 1718739..1719794 Mycobacterium tuberculosis KZN 1435 8163442 YP_003031528.1 CDS TBMG_01579 NC_012943.1 1719819 1720967 R PE-PGRS family protein complement(1719819..1720967) Mycobacterium tuberculosis KZN 1435 8163443 YP_003031529.1 CDS TBMG_01580 NC_012943.1 1721628 1723631 R hypothetical protein complement(1721628..1723631) Mycobacterium tuberculosis KZN 1435 8163444 YP_003031530.1 CDS TBMG_01581 NC_012943.1 1723762 1725693 R gamma-glutamyltranspeptidase precursor ggtB complement(1723762..1725693) Mycobacterium tuberculosis KZN 1435 8163445 YP_003031531.1 CDS TBMG_01582 NC_012943.1 1725730 1726575 R hypothetical protein complement(1725730..1726575) Mycobacterium tuberculosis KZN 1435 8163446 YP_003031532.1 CDS TBMG_01583 NC_012943.1 1726572 1727336 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(1726572..1727336) Mycobacterium tuberculosis KZN 1435 8163447 YP_003031533.1 CDS TBMG_01584 NC_012943.1 1727333 1729024 R ferredoxin-dependent nitrite reductase nirA complement(1727333..1729024) Mycobacterium tuberculosis KZN 1435 8163448 YP_003031534.1 CDS TBMG_01585 NC_012943.1 1729437 1729994 D hypothetical protein 1729437..1729994 Mycobacterium tuberculosis KZN 1435 8163449 YP_003031535.1 CDS TBMG_01586 NC_012943.1 1729991 1730455 D resuscitation-promoting factor rpfD 1729991..1730455 Mycobacterium tuberculosis KZN 1435 8163450 YP_003031536.1 CDS TBMG_01587 NC_012943.1 1730516 1731688 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1730516..1731688 Mycobacterium tuberculosis KZN 1435 8163451 YP_003031537.1 CDS TBMG_01588 NC_012943.1 1731685 1732938 R hypothetical protein complement(1731685..1732938) Mycobacterium tuberculosis KZN 1435 8163452 YP_003031538.1 CDS TBMG_01589 NC_012943.1 1733698 1735050 D catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function; salicylate synthase MbtI 1733698..1735050 Mycobacterium tuberculosis KZN 1435 8163453 YP_003031539.1 CDS TBMG_01590 NC_012943.1 1735054 1736037 R acetyl hydrolase mbtJ complement(1735054..1736037) Mycobacterium tuberculosis KZN 1435 8163454 YP_003031540.1 CDS TBMG_01591 NC_012943.1 1736070 1737767 R bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase mbtA complement(1736070..1737767) Mycobacterium tuberculosis KZN 1435 8163455 YP_003031541.1 CDS TBMG_01592 NC_012943.1 1737866 1742110 D phenyloxazoline synthase mbtB 1737866..1742110 Mycobacterium tuberculosis KZN 1435 8163456 YP_003031542.1 CDS TBMG_01593 NC_012943.1 1742100 1743434 D polyketide synthase 1742100..1743434 Mycobacterium tuberculosis KZN 1435 8163457 YP_003031543.1 CDS TBMG_01594 NC_012943.1 1743434 1746448 D polyketide synthase 1743434..1746448 Mycobacterium tuberculosis KZN 1435 8163458 YP_003031544.1 CDS TBMG_01595 NC_012943.1 1746441 1751636 D peptide synthetase mbtE 1746441..1751636 Mycobacterium tuberculosis KZN 1435 8163459 YP_003031545.1 CDS TBMG_01596 NC_012943.1 1751618 1756003 D peptide synthetase mbtF 1751618..1756003 Mycobacterium tuberculosis KZN 1435 8163460 YP_003031546.1 CDS TBMG_01597 NC_012943.1 1756000 1757295 D lysine-N-oxygenase mbtG 1756000..1757295 Mycobacterium tuberculosis KZN 1435 8162664 YP_003031547.1 CDS TBMG_01598 NC_012943.1 1757273 1757488 D hypothetical protein 1757273..1757488 Mycobacterium tuberculosis KZN 1435 8162665 YP_003031548.1 CDS TBMG_01599 NC_012943.1 1757588 1758094 D low molecular weight protein antigen cfp2 1757588..1758094 Mycobacterium tuberculosis KZN 1435 8162666 YP_003031549.1 CDS TBMG_01600 NC_012943.1 1758121 1758438 R hypothetical protein complement(1758121..1758438) Mycobacterium tuberculosis KZN 1435 8162667 YP_003031550.1 CDS hrcA NC_012943.1 1758610 1759641 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1758610..1759641 Mycobacterium tuberculosis KZN 1435 8162668 YP_003031551.1 CDS TBMG_01602 NC_012943.1 1759716 1760864 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 1759716..1760864 Mycobacterium tuberculosis KZN 1435 8162669 YP_003031552.1 CDS TBMG_01603 NC_012943.1 1760878 1761666 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1760878..1761666 Mycobacterium tuberculosis KZN 1435 8162670 YP_003031553.1 CDS TBMG_01604 NC_012943.1 1761765 1762052 R PE-PGRS family protein complement(1761765..1762052) Mycobacterium tuberculosis KZN 1435 8162671 YP_003031554.1 CDS TBMG_01605 NC_012943.1 1762145 1763458 D hypothetical protein 1762145..1763458 Mycobacterium tuberculosis KZN 1435 8162672 YP_003031555.1 CDS TBMG_04025 NC_012943.1 1763729 1764787 D phosphate starvation-inducible protein phoH1 1763729..1764787 Mycobacterium tuberculosis KZN 1435 8162673 YP_003031556.1 CDS TBMG_01608 NC_012943.1 1764791 1765339 D metalloprotease 1764791..1765339 Mycobacterium tuberculosis KZN 1435 8162674 YP_003031557.1 CDS TBMG_01609 NC_012943.1 1765336 1766643 D hypothetical protein 1765336..1766643 Mycobacterium tuberculosis KZN 1435 8162675 YP_003031558.1 CDS TBMG_01610 NC_012943.1 1766615 1766956 D hypothetical protein 1766615..1766956 Mycobacterium tuberculosis KZN 1435 8162676 YP_003031559.1 CDS era NC_012943.1 1767030 1767932 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1767030..1767932 Mycobacterium tuberculosis KZN 1435 8162677 YP_003031560.1 CDS TBMG_01612 NC_012943.1 1767929 1769383 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(1767929..1769383) Mycobacterium tuberculosis KZN 1435 8162678 YP_003031561.1 CDS recO NC_012943.1 1769445 1770242 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1769445..1770242 Mycobacterium tuberculosis KZN 1435 8162679 YP_003031562.1 CDS TBMG_01614 NC_012943.1 1770235 1771125 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 1770235..1771125 Mycobacterium tuberculosis KZN 1435 8162680 YP_003031563.1 CDS TBMG_01615 NC_012943.1 1771125 1771553 D hypothetical protein 1771125..1771553 Mycobacterium tuberculosis KZN 1435 8162681 YP_003031564.1 CDS TBMG_01616 NC_012943.1 1771661 1772053 R ferric uptake regulation protein furB complement(1771661..1772053) Mycobacterium tuberculosis KZN 1435 8162682 YP_003031565.1 CDS TBMG_01617 NC_012943.1 1772050 1772457 R transcriptional regulator, arsR-family complement(1772050..1772457) Mycobacterium tuberculosis KZN 1435 8162683 YP_003031566.1 CDS TBMG_01618 NC_012943.1 1772639 1774030 D Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1772639..1774030 Mycobacterium tuberculosis KZN 1435 8162684 YP_003031567.1 CDS TBMG_01619 NC_012943.1 1774168 1776015 D PPE family protein 1774168..1776015 Mycobacterium tuberculosis KZN 1435 8162685 YP_003031568.1 CDS TBMG_01620 NC_012943.1 1776753 1778621 D PPE family protein 1776753..1778621 Mycobacterium tuberculosis KZN 1435 8162686 YP_003031569.1 CDS TBMG_01621 NC_012943.1 1779051 1780226 D PPE family protein 1779051..1780226 Mycobacterium tuberculosis KZN 1435 8162687 YP_003031570.1 CDS TBMG_01622 NC_012943.1 1780315 1780614 D hypothetical protein 1780315..1780614 Mycobacterium tuberculosis KZN 1435 8162688 YP_003031571.1 CDS TBMG_01623 NC_012943.1 1780629 1780913 D hypothetical protein 1780629..1780913 Mycobacterium tuberculosis KZN 1435 8162689 YP_003031572.1 CDS TBMG_01624 NC_012943.1 1781168 1781494 D transposase 1781168..1781494 Mycobacterium tuberculosis KZN 1435 8162690 YP_003031573.1 CDS TBMG_01625 NC_012943.1 1781545 1782429 D transposase 1781545..1782429 Mycobacterium tuberculosis KZN 1435 8162691 YP_003031574.1 CDS TBMG_01626 NC_012943.1 1782493 1783668 D PPE family protein 1782493..1783668 Mycobacterium tuberculosis KZN 1435 8162692 YP_003031575.1 CDS TBMG_04026 NC_012943.1 1783799 1784026 R hypothetical protein complement(1783799..1784026) Mycobacterium tuberculosis KZN 1435 8162693 YP_003031576.1 CDS TBMG_01627 NC_012943.1 1784492 1786054 D membrane-associated phospholipase C 1 plcA 1784492..1786054 Mycobacterium tuberculosis KZN 1435 8162694 YP_003031577.1 CDS TBMG_01628 NC_012943.1 1786245 1787810 D membrane-associated phospholipase C 2 plcB 1786245..1787810 Mycobacterium tuberculosis KZN 1435 8162695 YP_003031578.1 CDS TBMG_01629 NC_012943.1 1787869 1789419 D phospholipase C 3 plcC 1787869..1789419 Mycobacterium tuberculosis KZN 1435 8162696 YP_003031579.1 CDS TBMG_01630 NC_012943.1 1789635 1789937 D hypothetical protein 1789635..1789937 Mycobacterium tuberculosis KZN 1435 8162697 YP_003031580.1 CDS TBMG_01631 NC_012943.1 1790072 1790368 D esat-6 like protein esxP 1790072..1790368 Mycobacterium tuberculosis KZN 1435 8162698 YP_003031581.1 CDS TBMG_01632 NC_012943.1 1790419 1790703 D esat-6 like protein esxO 1790419..1790703 Mycobacterium tuberculosis KZN 1435 8162699 YP_003031582.1 CDS TBMG_01633 NC_012943.1 1790788 1792770 R hypothetical protein complement(1790788..1792770) Mycobacterium tuberculosis KZN 1435 8162700 YP_003031583.1 CDS TBMG_01634 NC_012943.1 1792839 1794134 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1792839..1794134 Mycobacterium tuberculosis KZN 1435 8162701 YP_003031584.1 CDS dnaG NC_012943.1 1794139 1796058 D synthesizes RNA primers at the replication forks; DNA primase 1794139..1796058 Mycobacterium tuberculosis KZN 1435 8162702 YP_003031585.1 CDS TBMG_01636 NC_012943.1 1796062 1796355 R hypothetical protein complement(1796062..1796355) Mycobacterium tuberculosis KZN 1435 8162703 YP_003031586.1 CDS TBMG_01637 NC_012943.1 1796575 1797009 R hypothetical protein complement(1796575..1797009) Mycobacterium tuberculosis KZN 1435 8162704 YP_003031587.1 CDS TBMG_01638 NC_012943.1 1797587 1798924 D PE-PGRS family protein 1797587..1798924 Mycobacterium tuberculosis KZN 1435 8162706 YP_003031588.1 CDS TBMG_01639 NC_012943.1 1799010 1801898 R transmembrane transporter mmpL9 complement(1799010..1801898) Mycobacterium tuberculosis KZN 1435 8162707 YP_003031589.1 CDS TBMG_01640 NC_012943.1 1802528 1803484 D hypothetical protein 1802528..1803484 Mycobacterium tuberculosis KZN 1435 8162708 YP_003031590.1 CDS TBMG_01641 NC_012943.1 1803604 1804722 D hypothetical protein 1803604..1804722 Mycobacterium tuberculosis KZN 1435 8162709 YP_003031591.1 CDS TBMG_01642 NC_012943.1 1804786 1805754 R hypothetical protein complement(1804786..1805754) Mycobacterium tuberculosis KZN 1435 8162710 YP_003031592.1 CDS TBMG_01643 NC_012943.1 1806170 1806859 R serine acetyltransferase cysE complement(1806170..1806859) Mycobacterium tuberculosis KZN 1435 8162711 YP_003031593.1 CDS TBMG_01644 NC_012943.1 1806863 1807651 R truncated CDS; cysteine synthase A cysK1 complement(1806863..1807651) Mycobacterium tuberculosis KZN 1435 8162712 YP_003031594.1 CDS TBMG_01645 NC_012943.1 1808271 1809884 D membrane transporter 1808271..1809884 Mycobacterium tuberculosis KZN 1435 8162713 YP_003031595.1 CDS TBMG_01646 NC_012943.1 1809838 1811484 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1809838..1811484) Mycobacterium tuberculosis KZN 1435 8162714 YP_003031596.1 CDS TBMG_01647 NC_012943.1 1811514 1811852 R hypothetical protein complement(1811514..1811852) Mycobacterium tuberculosis KZN 1435 8162715 YP_003031597.1 CDS TBMG_01648 NC_012943.1 1811909 1812295 R hypothetical protein complement(1811909..1812295) Mycobacterium tuberculosis KZN 1435 8162716 YP_003031598.1 CDS TBMG_01649 NC_012943.1 1812370 1812897 D hypothetical protein 1812370..1812897 Mycobacterium tuberculosis KZN 1435 8162717 YP_003031599.1 CDS TBMG_01650 NC_012943.1 1813131 1814678 D nitrite extrusion protein 1 narK1 1813131..1814678 Mycobacterium tuberculosis KZN 1435 8162718 YP_003031600.1 CDS TBMG_01651 NC_012943.1 1814713 1815861 R PE family protein complement(1814713..1815861) Mycobacterium tuberculosis KZN 1435 8162719 YP_003031601.1 CDS TBMG_01652 NC_012943.1 1816113 1816604 R hypothetical protein complement(1816113..1816604) Mycobacterium tuberculosis KZN 1435 8162720 YP_003031602.1 CDS TBMG_01653 NC_012943.1 1816645 1818738 D transmembrane ATP-binding protein ABC transporter 1816645..1818738 Mycobacterium tuberculosis KZN 1435 8162721 YP_003031603.1 CDS TBMG_01654 NC_012943.1 1818735 1819583 D hypothetical protein 1818735..1819583 Mycobacterium tuberculosis KZN 1435 8162722 YP_003031604.1 CDS TBMG_01655 NC_012943.1 1819812 1820258 R transcriptional regulator, asnC-family complement(1819812..1820258) Mycobacterium tuberculosis KZN 1435 8162723 YP_003031605.1 CDS TBMG_01656 NC_012943.1 1820323 1821231 D hypothetical protein 1820323..1821231 Mycobacterium tuberculosis KZN 1435 8162724 YP_003031606.1 CDS TBMG_01657 NC_012943.1 1821204 1821893 D ornithine aminotransferase rocD1 1821204..1821893 Mycobacterium tuberculosis KZN 1435 8162725 YP_003031607.1 CDS TBMG_01658 NC_012943.1 1821887 1822438 D ornithine aminotransferase rocD2 1821887..1822438 Mycobacterium tuberculosis KZN 1435 8162726 YP_003031608.1 CDS TBMG_01659 NC_012943.1 1822439 1823869 D hypothetical protein 1822439..1823869 Mycobacterium tuberculosis KZN 1435 8162727 YP_003031609.1 CDS TBMG_01660 NC_012943.1 1823866 1824744 D hypothetical protein 1823866..1824744 Mycobacterium tuberculosis KZN 1435 8162728 YP_003031610.1 CDS TBMG_01661 NC_012943.1 1824752 1826074 R periplasmic sugar-binding lipoprotein uspC complement(1824752..1826074) Mycobacterium tuberculosis KZN 1435 8162729 YP_003031611.1 CDS TBMG_01662 NC_012943.1 1826071 1826895 R hypothetical protein complement(1826071..1826895) Mycobacterium tuberculosis KZN 1435 8162730 YP_003031612.1 CDS TBMG_01663 NC_012943.1 1826882 1827754 R hypothetical protein complement(1826882..1827754) Mycobacterium tuberculosis KZN 1435 8162731 YP_003031613.1 CDS TBMG_01664 NC_012943.1 1827788 1829305 D hypothetical protein 1827788..1829305 Mycobacterium tuberculosis KZN 1435 8162732 YP_003031614.1 CDS TBMG_01665 NC_012943.1 1829302 1830675 D hypothetical protein 1829302..1830675 Mycobacterium tuberculosis KZN 1435 8162733 YP_003031615.1 CDS TBMG_01666 NC_012943.1 1830686 1831540 D hypothetical protein 1830686..1831540 Mycobacterium tuberculosis KZN 1435 8162734 YP_003031616.1 CDS TBMG_01667 NC_012943.1 1831837 1832106 R hypothetical protein complement(1831837..1832106) Mycobacterium tuberculosis KZN 1435 8162735 YP_003031617.1 CDS TBMG_01668 NC_012943.1 1832184 1832780 R hypothetical protein complement(1832184..1832780) Mycobacterium tuberculosis KZN 1435 8162736 YP_003031618.1 CDS TBMG_01669 NC_012943.1 1832813 1833157 R excisionase complement(1832813..1833157) Mycobacterium tuberculosis KZN 1435 8162737 YP_003031619.1 CDS TBMG_04027 NC_012943.1 1833163 1833315 R hypothetical protein complement(1833163..1833315) Mycobacterium tuberculosis KZN 1435 8162738 YP_003031620.1 CDS TBMG_04028 NC_012943.1 1833260 1833547 R hypothetical protein complement(1833260..1833547) Mycobacterium tuberculosis KZN 1435 8162739 YP_003031621.1 CDS TBMG_01671 NC_012943.1 1834294 1834749 D integrase 1834294..1834749 Mycobacterium tuberculosis KZN 1435 8162740 YP_003031622.1 CDS TBMG_01672 NC_012943.1 1834845 1835168 D hypothetical protein 1834845..1835168 Mycobacterium tuberculosis KZN 1435 8162742 YP_003031623.1 CDS TBMG_01673 NC_012943.1 1835115 1835447 R hypothetical protein complement(1835115..1835447) Mycobacterium tuberculosis KZN 1435 8162743 YP_003031624.1 CDS TBMG_01674 NC_012943.1 1835457 1836173 R hypothetical protein complement(1835457..1836173) Mycobacterium tuberculosis KZN 1435 8161319 YP_003031625.1 CDS TBMG_01675 NC_012943.1 1836657 1837088 D hypothetical protein 1836657..1837088 Mycobacterium tuberculosis KZN 1435 8161320 YP_003031626.1 CDS TBMG_01676 NC_012943.1 1837173 1837364 D hypothetical protein 1837173..1837364 Mycobacterium tuberculosis KZN 1435 8161321 YP_003031627.1 CDS TBMG_01677 NC_012943.1 1837896 1838741 D hypothetical protein 1837896..1838741 Mycobacterium tuberculosis KZN 1435 8161322 YP_003031628.1 CDS TBMG_04029 NC_012943.1 1838670 1839104 R hypothetical protein complement(1838670..1839104) Mycobacterium tuberculosis KZN 1435 8161323 YP_003031629.1 CDS TBMG_04030 NC_012943.1 1838891 1839484 R hypothetical protein complement(1838891..1839484) Mycobacterium tuberculosis KZN 1435 8161324 YP_003031630.1 CDS TBMG_01679 NC_012943.1 1839494 1840783 R hypothetical protein complement(1839494..1840783) Mycobacterium tuberculosis KZN 1435 8161325 YP_003031631.1 CDS TBMG_01680 NC_012943.1 1841573 1842496 D antibiotic-resistance protein 1841573..1842496 Mycobacterium tuberculosis KZN 1435 8161326 YP_003031632.1 CDS TBMG_01681 NC_012943.1 1842537 1842779 R hypothetical protein complement(1842537..1842779) Mycobacterium tuberculosis KZN 1435 8161327 YP_003031633.1 CDS TBMG_01682 NC_012943.1 1842885 1843544 R cutinase cut2 complement(1842885..1843544) Mycobacterium tuberculosis KZN 1435 8161328 YP_003031634.1 CDS TBMG_01683 NC_012943.1 1843584 1844516 D hypothetical protein 1843584..1844516 Mycobacterium tuberculosis KZN 1435 8161329 YP_003031635.1 CDS TBMG_01684 NC_012943.1 1844590 1846533 D molecular chaperone; heat shock protein 90 1844590..1846533 Mycobacterium tuberculosis KZN 1435 8161330 YP_003031636.1 CDS TBMG_01685 NC_012943.1 1846539 1847606 R hypothetical protein complement(1846539..1847606) Mycobacterium tuberculosis KZN 1435 8161331 YP_003031637.1 CDS TBMG_01686 NC_012943.1 1847702 1848154 R hypothetical protein complement(1847702..1848154) Mycobacterium tuberculosis KZN 1435 8161332 YP_003031638.1 CDS TBMG_01687 NC_012943.1 1848186 1849088 R haloalkane dehalogenase complement(1848186..1849088) Mycobacterium tuberculosis KZN 1435 8161333 YP_003031639.1 CDS TBMG_01688 NC_012943.1 1849182 1849820 R hypothetical protein complement(1849182..1849820) Mycobacterium tuberculosis KZN 1435 8161334 YP_003031640.1 CDS TBMG_01689 NC_012943.1 1850042 1851265 R aminotransferase complement(1850042..1851265) Mycobacterium tuberculosis KZN 1435 8161335 YP_003031641.1 CDS TBMG_01690 NC_012943.1 1851560 1852300 D hypothetical protein 1851560..1852300 Mycobacterium tuberculosis KZN 1435 8161336 YP_003031642.1 CDS TBMG_01691 NC_012943.1 1852339 1852563 D hypothetical protein 1852339..1852563 Mycobacterium tuberculosis KZN 1435 8161337 YP_003031643.1 CDS TBMG_01692 NC_012943.1 1852564 1853418 R thiosulfate sulfurtransferase sseB complement(1852564..1853418) Mycobacterium tuberculosis KZN 1435 8161338 YP_003031644.1 CDS TBMG_01693 NC_012943.1 1853478 1854050 R hypothetical protein complement(1853478..1854050) Mycobacterium tuberculosis KZN 1435 8161339 YP_003031645.1 CDS TBMG_01694 NC_012943.1 1854135 1854917 R CDP-diacylglycerol pyrophosphatase complement(1854135..1854917) Mycobacterium tuberculosis KZN 1435 8161340 YP_003031646.1 CDS TBMG_01695 NC_012943.1 1854887 1855264 R hypothetical protein complement(1854887..1855264) Mycobacterium tuberculosis KZN 1435 8161341 YP_003031647.1 CDS TBMG_01696 NC_012943.1 1855261 1856889 R membrane transporter yjcE complement(1855261..1856889) Mycobacterium tuberculosis KZN 1435 8161342 YP_003031648.1 CDS TBMG_01697 NC_012943.1 1857023 1857715 D hypothetical protein 1857023..1857715 Mycobacterium tuberculosis KZN 1435 8161343 YP_003031649.1 CDS TBMG_01698 NC_012943.1 1857782 1859119 R hypothetical protein complement(1857782..1859119) Mycobacterium tuberculosis KZN 1435 8161344 YP_003031650.1 CDS TBMG_01699 NC_012943.1 1859152 1860447 R esterase lipM complement(1859152..1860447) Mycobacterium tuberculosis KZN 1435 8161345 YP_003031651.1 CDS TBMG_01700 NC_012943.1 1860715 1861041 D transposase 1860715..1861041 Mycobacterium tuberculosis KZN 1435 8161346 YP_003031652.1 CDS TBMG_01701 NC_012943.1 1861092 1861976 D transposase 1861092..1861976 Mycobacterium tuberculosis KZN 1435 8161347 YP_003031653.1 CDS TBMG_01702 NC_012943.1 1862074 1863012 D LysR family transcriptional regulator 1862074..1863012 Mycobacterium tuberculosis KZN 1435 8161348 YP_003031654.1 CDS TBMG_01703 NC_012943.1 1863119 1864777 R phosphate-transport permease pitB complement(1863119..1864777) Mycobacterium tuberculosis KZN 1435 8161349 YP_003031655.1 CDS TBMG_01704 NC_012943.1 1865011 1866390 R dehydrogenase complement(1865011..1866390) Mycobacterium tuberculosis KZN 1435 8161350 YP_003031656.1 CDS TBMG_01705 NC_012943.1 1866554 1867468 D glycerolphosphodiesterase 1866554..1867468 Mycobacterium tuberculosis KZN 1435 8161351 YP_003031657.1 CDS TBMG_01706 NC_012943.1 1867653 1868843 R cytochrome P450 121 cyp121 complement(1867653..1868843) Mycobacterium tuberculosis KZN 1435 8161352 YP_003031658.1 CDS TBMG_01707 NC_012943.1 1868840 1869373 R hypothetical protein complement(1868840..1869373) Mycobacterium tuberculosis KZN 1435 8161353 YP_003031659.1 CDS TBMG_04031 NC_012943.1 1869505 1869753 D antitoxin 1869505..1869753 Mycobacterium tuberculosis KZN 1435 8161354 YP_003031660.1 CDS TBMG_01708 NC_012943.1 1869787 1870104 D toxin 1869787..1870104 Mycobacterium tuberculosis KZN 1435 8161355 YP_003031661.1 CDS TBMG_01709 NC_012943.1 1870161 1870490 R hypothetical protein complement(1870161..1870490) Mycobacterium tuberculosis KZN 1435 8161356 YP_003031662.1 CDS TBMG_01710 NC_012943.1 1870487 1870855 R hypothetical protein complement(1870487..1870855) Mycobacterium tuberculosis KZN 1435 8161357 YP_003031663.1 CDS TBMG_01711 NC_012943.1 1870961 1871260 R hypothetical protein complement(1870961..1871260) Mycobacterium tuberculosis KZN 1435 8161358 YP_003031664.1 CDS TBMG_01712 NC_012943.1 1871367 1871894 R hypothetical protein complement(1871367..1871894) Mycobacterium tuberculosis KZN 1435 8161359 YP_003031665.1 CDS TBMG_01713 NC_012943.1 1871971 1872303 D hypothetical protein 1871971..1872303 Mycobacterium tuberculosis KZN 1435 8161360 YP_003031666.1 CDS TBMG_01714 NC_012943.1 1872316 1873785 D cytochrome P450 128 cyp128 1872316..1873785 Mycobacterium tuberculosis KZN 1435 8161361 YP_003031667.1 CDS TBMG_01715 NC_012943.1 1873782 1874948 D hypothetical protein 1873782..1874948 Mycobacterium tuberculosis KZN 1435 8161362 YP_003031668.1 CDS TBMG_01716 NC_012943.1 1875202 1876488 R cytochrome P450 124 cyp124 complement(1875202..1876488) Mycobacterium tuberculosis KZN 1435 8161363 YP_003031669.1 CDS TBMG_01717 NC_012943.1 1876663 1877892 R hypothetical protein complement(1876663..1877892) Mycobacterium tuberculosis KZN 1435 8161364 YP_003031670.1 CDS TBMG_01718 NC_012943.1 1878242 1880020 D hypothetical protein 1878242..1880020 Mycobacterium tuberculosis KZN 1435 8161365 YP_003031671.1 CDS TBMG_01719 NC_012943.1 1879998 1880951 R short chain dehydrogenase complement(1879998..1880951) Mycobacterium tuberculosis KZN 1435 8161366 YP_003031672.1 CDS TBMG_01720 NC_012943.1 1880950 1882548 D apolipoprotein N-acyltransferase 1880950..1882548 Mycobacterium tuberculosis KZN 1435 8161368 YP_003031673.1 CDS TBMG_01721 NC_012943.1 1882625 1883263 R hypothetical protein complement(1882625..1883263) Mycobacterium tuberculosis KZN 1435 8161367 YP_003031674.1 CDS TBMG_01722 NC_012943.1 1883260 1884345 R zinc-type alcohol dehydrogenase adhE2 complement(1883260..1884345) Mycobacterium tuberculosis KZN 1435 8161369 YP_003031675.1 CDS TBMG_01723 NC_012943.1 1884693 1885754 D transcriptional regulator 1884693..1885754 Mycobacterium tuberculosis KZN 1435 8161370 YP_003031676.1 CDS TBMG_01724 NC_012943.1 1885768 1886586 D hypothetical protein 1885768..1886586 Mycobacterium tuberculosis KZN 1435 8161371 YP_003031677.1 CDS TBMG_01725 NC_012943.1 1886716 1887249 D hypothetical protein 1886716..1887249 Mycobacterium tuberculosis KZN 1435 8161372 YP_003031678.1 CDS TBMG_04032 NC_012943.1 1887278 1887496 R hypothetical protein complement(1887278..1887496) Mycobacterium tuberculosis KZN 1435 8161373 YP_003031679.1 CDS TBMG_01726 NC_012943.1 1887615 1888070 D hypothetical protein 1887615..1888070 Mycobacterium tuberculosis KZN 1435 8161374 YP_003031680.1 CDS TBMG_01727 NC_012943.1 1888103 1888606 R hypothetical protein complement(1888103..1888606) Mycobacterium tuberculosis KZN 1435 8161375 YP_003031681.1 CDS TBMG_01728 NC_012943.1 1888672 1889601 R involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); the enzyme from Mycobacterium tuberculosis can phosphorylate a variety of amphipathic lipids; diacylglycerol kinase complement(1888672..1889601) Mycobacterium tuberculosis KZN 1435 8161376 YP_003031682.1 CDS TBMG_01729 NC_012943.1 1889598 1891187 R flavoprotein complement(1889598..1891187) Mycobacterium tuberculosis KZN 1435 8161377 YP_003031683.1 CDS TBMG_01730 NC_012943.1 1891235 1891804 D transcriptional regulator 1891235..1891804 Mycobacterium tuberculosis KZN 1435 8161378 YP_003031684.1 CDS TBMG_01731 NC_012943.1 1891798 1893348 D glycerol-3-phosphate dehydrogenase glpD1 1891798..1893348 Mycobacterium tuberculosis KZN 1435 8161379 YP_003031685.1 CDS TBMG_01732 NC_012943.1 1893417 1894304 R hypothetical protein complement(1893417..1894304) Mycobacterium tuberculosis KZN 1435 8161380 YP_003031686.1 CDS TBMG_01733 NC_012943.1 1894428 1895849 R acetyl/propionyl-CoA carboxylase beta subunit accD6 complement(1894428..1895849) Mycobacterium tuberculosis KZN 1435 8161381 YP_003031687.1 CDS TBMG_01734 NC_012943.1 1895880 1897196 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(1895880..1897196) Mycobacterium tuberculosis KZN 1435 8161382 YP_003031688.1 CDS TBMG_01735 NC_012943.1 1897397 1898476 R truncated CDS; 3-oxoacyl-ACP synthase complement(1897397..1898476) Mycobacterium tuberculosis KZN 1435 8161383 YP_003031689.1 CDS acpP NC_012943.1 1898473 1898820 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(1898473..1898820) Mycobacterium tuberculosis KZN 1435 8161384 YP_003031690.1 CDS TBMG_01737 NC_012943.1 1898896 1899804 R malonyl CoA-acyl carrier protein transacylase fabD complement(1898896..1899804) Mycobacterium tuberculosis KZN 1435 8161385 YP_003031691.1 CDS TBMG_01738 NC_012943.1 1900043 1901287 R hypothetical protein complement(1900043..1901287) Mycobacterium tuberculosis KZN 1435 8161386 YP_003031692.1 CDS aceE NC_012943.1 1901347 1904139 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(1901347..1904139) Mycobacterium tuberculosis KZN 1435 8161387 YP_003031693.1 CDS TBMG_01740 NC_012943.1 1904104 1904901 D hypothetical protein 1904104..1904901 Mycobacterium tuberculosis KZN 1435 8161389 YP_003031694.1 CDS TBMG_01741 NC_012943.1 1904939 1905415 D hypothetical protein 1904939..1905415 Mycobacterium tuberculosis KZN 1435 8161388 YP_003031695.1 CDS TBMG_01742 NC_012943.1 1905415 1905876 D peroxiredoxin ahpE 1905415..1905876 Mycobacterium tuberculosis KZN 1435 8161390 YP_003031696.1 CDS TBMG_04033 NC_012943.1 1906004 1906240 D hypothetical protein 1906004..1906240 Mycobacterium tuberculosis KZN 1435 8161392 YP_003031697.1 CDS TBMG_01743 NC_012943.1 1906335 1907150 R hypothetical protein complement(1906335..1907150) Mycobacterium tuberculosis KZN 1435 8161393 YP_003031698.1 CDS cobD NC_012943.1 1907198 1908157 D CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 1907198..1908157 Mycobacterium tuberculosis KZN 1435 8161394 YP_003031699.1 CDS TBMG_01745 NC_012943.1 1908139 1908954 R hypothetical protein complement(1908139..1908954) Mycobacterium tuberculosis KZN 1435 8161395 YP_003031700.1 CDS TBMG_01746 NC_012943.1 1908954 1909445 R phosphotyrosine protein phosphatase ptpA complement(1908954..1909445) Mycobacterium tuberculosis KZN 1435 8161396 YP_003031701.1 CDS TBMG_01747 NC_012943.1 1909438 1910196 R hypothetical protein complement(1909438..1910196) Mycobacterium tuberculosis KZN 1435 8161397 YP_003031702.1 CDS TBMG_04034 NC_012943.1 1910208 1910384 D antitoxin 1910208..1910384 Mycobacterium tuberculosis KZN 1435 8161398 YP_003031703.1 CDS TBMG_01748 NC_012943.1 1910436 1910855 D toxin 1910436..1910855 Mycobacterium tuberculosis KZN 1435 8161399 YP_003031704.1 CDS TBMG_01749 NC_012943.1 1910892 1911986 D hypothetical protein 1910892..1911986 Mycobacterium tuberculosis KZN 1435 8161484 YP_003031705.1 CDS TBMG_01750 NC_012943.1 1911983 1913122 D hypothetical protein 1911983..1913122 Mycobacterium tuberculosis KZN 1435 8161486 YP_003031706.1 CDS TBMG_01751 NC_012943.1 1913119 1913856 D hypothetical protein 1913119..1913856 Mycobacterium tuberculosis KZN 1435 8161487 YP_003031707.1 CDS TBMG_01752 NC_012943.1 1913853 1914947 D bifunctional RNase H/acid phosphatase 1913853..1914947 Mycobacterium tuberculosis KZN 1435 8161488 YP_003031708.1 CDS TBMG_01753 NC_012943.1 1914959 1915660 R hypothetical protein complement(1914959..1915660) Mycobacterium tuberculosis KZN 1435 8161489 YP_003031709.1 CDS TBMG_01754 NC_012943.1 1916218 1917759 R hypothetical protein complement(1916218..1917759) Mycobacterium tuberculosis KZN 1435 8161490 YP_003031710.1 CDS panB NC_012943.1 1918004 1918849 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(1918004..1918849) Mycobacterium tuberculosis KZN 1435 8161491 YP_003031711.1 CDS TBMG_01756 NC_012943.1 1919568 1921130 D exported protease 1919568..1921130 Mycobacterium tuberculosis KZN 1435 8161492 YP_003031712.1 CDS TBMG_01757 NC_012943.1 1921192 1922754 D exported protease 1921192..1922754 Mycobacterium tuberculosis KZN 1435 8161493 YP_003031713.1 CDS TBMG_01758 NC_012943.1 1922849 1924189 D glutamine synthetase glnA2 1922849..1924189 Mycobacterium tuberculosis KZN 1435 8161494 YP_003031714.1 CDS TBMG_01759 NC_012943.1 1924238 1927222 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1924238..1927222 Mycobacterium tuberculosis KZN 1435 8161495 YP_003031715.1 CDS TBMG_01760 NC_012943.1 1927540 1928976 R glutamine synthetase glnA1 complement(1927540..1928976) Mycobacterium tuberculosis KZN 1435 8161496 YP_003031716.1 CDS TBMG_01761 NC_012943.1 1929175 1929597 D hypothetical protein 1929175..1929597 Mycobacterium tuberculosis KZN 1435 8161497 YP_003031717.1 CDS TBMG_01762 NC_012943.1 1929604 1930356 R hypothetical protein complement(1929604..1930356) Mycobacterium tuberculosis KZN 1435 8161498 YP_003031718.1 CDS TBMG_01763 NC_012943.1 1930383 1931318 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1930383..1931318) Mycobacterium tuberculosis KZN 1435 8161499 YP_003031719.1 CDS TBMG_01764 NC_012943.1 1931315 1932007 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1931315..1932007) Mycobacterium tuberculosis KZN 1435 8161500 YP_003031720.1 CDS TBMG_01765 NC_012943.1 1932060 1932965 R hypothetical protein complement(1932060..1932965) Mycobacterium tuberculosis KZN 1435 8161501 YP_003031721.1 CDS TBMG_01766 NC_012943.1 1932965 1934626 R dihydrolipoamide acetyltransferase complement(1932965..1934626) Mycobacterium tuberculosis KZN 1435 8161502 YP_003031722.1 CDS TBMG_01767 NC_012943.1 1934890 1936668 D short chain dehydrogenase 1934890..1936668 Mycobacterium tuberculosis KZN 1435 8161503 YP_003031723.1 CDS TBMG_01768 NC_012943.1 1936706 1938253 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(1936706..1938253) Mycobacterium tuberculosis KZN 1435 8161504 YP_003031724.1 CDS TBMG_01769 NC_012943.1 1938265 1939401 R hypothetical protein complement(1938265..1939401) Mycobacterium tuberculosis KZN 1435 8161505 YP_003031725.1 CDS gcvT NC_012943.1 1939410 1940549 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1939410..1940549 Mycobacterium tuberculosis KZN 1435 8161506 YP_003031726.1 CDS TBMG_01771 NC_012943.1 1940621 1941727 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1940621..1941727 Mycobacterium tuberculosis KZN 1435 8161507 YP_003031727.1 CDS TBMG_01772 NC_012943.1 1941653 1943191 R hypothetical protein complement(1941653..1943191) Mycobacterium tuberculosis KZN 1435 8161508 YP_003031728.1 CDS cobS NC_012943.1 1943349 1944098 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(1943349..1944098) Mycobacterium tuberculosis KZN 1435 8161509 YP_003031729.1 CDS cobT NC_012943.1 1944095 1945180 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(1944095..1945180) Mycobacterium tuberculosis KZN 1435 8161510 YP_003031730.1 CDS TBMG_01775 NC_012943.1 1945259 1945969 R hypothetical protein complement(1945259..1945969) Mycobacterium tuberculosis KZN 1435 8161511 YP_003031731.1 CDS TBMG_01776 NC_012943.1 1946059 1947204 D hypothetical protein 1946059..1947204 Mycobacterium tuberculosis KZN 1435 8161512 YP_003031732.1 CDS TBMG_01777 NC_012943.1 1947304 1947660 D hypothetical protein 1947304..1947660 Mycobacterium tuberculosis KZN 1435 8161513 YP_003031733.1 CDS TBMG_01778 NC_012943.1 1947668 1948360 R hypothetical protein complement(1947668..1948360) Mycobacterium tuberculosis KZN 1435 8161514 YP_003031734.1 CDS TBMG_01779 NC_012943.1 1948564 1949538 D carbohydrate kinase cbhK 1948564..1949538 Mycobacterium tuberculosis KZN 1435 8161515 YP_003031735.1 CDS TBMG_01780 NC_012943.1 1949636 1951594 R asparagine synthetase asnB complement(1949636..1951594) Mycobacterium tuberculosis KZN 1435 8161516 YP_003031736.1 CDS TBMG_01781 NC_012943.1 1951840 1952931 D transmembrane cytochrome C oxidase subunit II ctaC 1951840..1952931 Mycobacterium tuberculosis KZN 1435 8161517 YP_003031737.1 CDS TBMG_01782 NC_012943.1 1952939 1953358 D hypothetical protein 1952939..1953358 Mycobacterium tuberculosis KZN 1435 8161518 YP_003031738.1 CDS TBMG_01783 NC_012943.1 1953544 1954443 D hypothetical protein 1953544..1954443 Mycobacterium tuberculosis KZN 1435 8161519 YP_003031739.1 CDS TBMG_01784 NC_012943.1 1954443 1955087 D hypothetical protein 1954443..1955087 Mycobacterium tuberculosis KZN 1435 8161520 YP_003031740.1 CDS TBMG_01785 NC_012943.1 1955207 1956856 R ubiquinol-cytochrome C reductase qcrB cytochrome B subunit complement(1955207..1956856) Mycobacterium tuberculosis KZN 1435 8161521 YP_003031741.1 CDS TBMG_01786 NC_012943.1 1956853 1958142 R Rieske iron-sulfur protein qcrA complement(1956853..1958142) Mycobacterium tuberculosis KZN 1435 8161522 YP_003031742.1 CDS TBMG_01787 NC_012943.1 1958139 1958897 R ubiquinol-cytochrome C reductase qcrC cytochrome C subunit complement(1958139..1958897) Mycobacterium tuberculosis KZN 1435 8161523 YP_003031743.1 CDS TBMG_01788 NC_012943.1 1959022 1959633 R cytochrome C oxidase subunit III ctaE complement(1959022..1959633) Mycobacterium tuberculosis KZN 1435 8161524 YP_003031744.1 CDS trpD NC_012943.1 1959791 1960903 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1959791..1960903 Mycobacterium tuberculosis KZN 1435 8161525 YP_003031745.1 CDS TBMG_04035 NC_012943.1 1960778 1962715 R contains 3'-5'exonuclease domain; hypothetical protein complement(1960778..1962715) Mycobacterium tuberculosis KZN 1435 8161526 YP_003031746.1 CDS TBMG_01790 NC_012943.1 1962798 1963076 D hypothetical protein 1962798..1963076 Mycobacterium tuberculosis KZN 1435 8161527 YP_003031747.1 CDS TBMG_01791 NC_012943.1 1963238 1964419 D hypothetical protein 1963238..1964419 Mycobacterium tuberculosis KZN 1435 8161528 YP_003031748.1 CDS TBMG_01792 NC_012943.1 1964514 1965287 D hypothetical protein 1964514..1965287 Mycobacterium tuberculosis KZN 1435 8161529 YP_003031749.1 CDS TBMG_01793 NC_012943.1 1965384 1966541 D hypothetical protein 1965384..1966541 Mycobacterium tuberculosis KZN 1435 8161530 YP_003031750.1 CDS TBMG_01794 NC_012943.1 1966572 1968383 R long-chain fatty-acid-CoA ligase fadD15 complement(1966572..1968383) Mycobacterium tuberculosis KZN 1435 8161531 YP_003031751.1 CDS TBMG_01795 NC_012943.1 1968540 1968929 D hypothetical protein 1968540..1968929 Mycobacterium tuberculosis KZN 1435 8161532 YP_003031752.1 CDS TBMG_01796 NC_012943.1 1969034 1969468 D hypothetical protein 1969034..1969468 Mycobacterium tuberculosis KZN 1435 8161533 YP_003031753.1 CDS TBMG_01797 NC_012943.1 1969585 1970727 D hypothetical protein 1969585..1970727 Mycobacterium tuberculosis KZN 1435 8161534 YP_003031754.1 CDS TBMG_01798 NC_012943.1 1970724 1971119 D hypothetical protein 1970724..1971119 Mycobacterium tuberculosis KZN 1435 8161535 YP_003031755.1 CDS TBMG_01799 NC_012943.1 1971205 1971948 D 1-acylglycerol-3-phosphate O-acyltransferase 1971205..1971948 Mycobacterium tuberculosis KZN 1435 8161536 YP_003031756.1 CDS TBMG_01800 NC_012943.1 1971949 1973232 R hypothetical protein complement(1971949..1973232) Mycobacterium tuberculosis KZN 1435 8161537 YP_003031757.1 CDS TBMG_01801 NC_012943.1 1973269 1974207 D hypothetical protein 1973269..1974207 Mycobacterium tuberculosis KZN 1435 8161538 YP_003031758.1 CDS TBMG_01802 NC_012943.1 1974217 1974723 D hypothetical protein 1974217..1974723 Mycobacterium tuberculosis KZN 1435 8161539 YP_003031759.1 CDS TBMG_01803 NC_012943.1 1974814 1976202 D 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase 1974814..1976202 Mycobacterium tuberculosis KZN 1435 8161540 YP_003031760.1 CDS TBMG_01804 NC_012943.1 1976470 1976652 D hypothetical protein 1976470..1976652 Mycobacterium tuberculosis KZN 1435 8161541 YP_003031761.1 CDS TBMG_01805 NC_012943.1 1976586 1977251 D transposase 1976586..1977251 Mycobacterium tuberculosis KZN 1435 8161542 YP_003031762.1 CDS TBMG_01806 NC_012943.1 1977393 1978592 R Ser/Thr protein kinase complement(1977393..1978592) Mycobacterium tuberculosis KZN 1435 8161543 YP_003031763.1 CDS TBMG_01807 NC_012943.1 1978647 1979087 D hypothetical protein 1978647..1979087 Mycobacterium tuberculosis KZN 1435 8161544 YP_003031764.1 CDS TBMG_01808 NC_012943.1 1979074 1980624 R hypothetical protein complement(1979074..1980624) Mycobacterium tuberculosis KZN 1435 8161545 YP_003031765.1 CDS TBMG_01809 NC_012943.1 1980628 1981686 R geranylgeranyl pyrophosphate synthetase idsA2 complement(1980628..1981686) Mycobacterium tuberculosis KZN 1435 8161546 YP_003031766.1 CDS TBMG_01810 NC_012943.1 1981979 1982902 D hypothetical protein 1981979..1982902 Mycobacterium tuberculosis KZN 1435 8161547 YP_003031767.1 CDS TBMG_01811 NC_012943.1 1982899 1983582 R hypothetical protein complement(1982899..1983582) Mycobacterium tuberculosis KZN 1435 8161548 YP_003031768.1 CDS TBMG_01812 NC_012943.1 1983678 1984298 R hypothetical protein complement(1983678..1984298) Mycobacterium tuberculosis KZN 1435 8161549 YP_003031769.1 CDS TBMG_01813 NC_012943.1 1984564 1984968 D hypothetical protein 1984564..1984968 Mycobacterium tuberculosis KZN 1435 8161550 YP_003031770.1 CDS TBMG_01814 NC_012943.1 1985317 1985748 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1985317..1985748 Mycobacterium tuberculosis KZN 1435 8161551 YP_003031771.1 CDS mraW NC_012943.1 1985750 1986940 D S-adenosyl-methyltransferase MraW 1985750..1986940 Mycobacterium tuberculosis KZN 1435 8161552 YP_003031772.1 CDS TBMG_01816 NC_012943.1 1986937 1988091 D hypothetical protein 1986937..1988091 Mycobacterium tuberculosis KZN 1435 8161553 YP_003031773.1 CDS TBMG_01817 NC_012943.1 1988088 1990127 D hypothetical protein 1988088..1990127 Mycobacterium tuberculosis KZN 1435 8161554 YP_003031774.1 CDS TBMG_04036 NC_012943.1 1990337 1991935 D PE-PGRS family protein 1990337..1991935 Mycobacterium tuberculosis KZN 1435 8161555 YP_003031775.1 CDS TBMG_01820 NC_012943.1 1992038 1992904 D hypothetical protein 1992038..1992904 Mycobacterium tuberculosis KZN 1435 8161556 YP_003031776.1 CDS TBMG_01821 NC_012943.1 1993172 1993513 D hypothetical protein 1993172..1993513 Mycobacterium tuberculosis KZN 1435 8161557 YP_003031777.1 CDS TBMG_01822 NC_012943.1 1993510 1994544 D hypothetical protein 1993510..1994544 Mycobacterium tuberculosis KZN 1435 8161558 YP_003031778.1 CDS murE NC_012943.1 1994567 1996174 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1994567..1996174 Mycobacterium tuberculosis KZN 1435 8161559 YP_003031779.1 CDS TBMG_01824 NC_012943.1 1996171 1997703 D UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 1996171..1997703 Mycobacterium tuberculosis KZN 1435 8161560 YP_003031780.1 CDS mraY NC_012943.1 1997700 1998779 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1997700..1998779 Mycobacterium tuberculosis KZN 1435 8161561 YP_003031781.1 CDS murD NC_012943.1 1998772 2000241 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1998772..2000241 Mycobacterium tuberculosis KZN 1435 8161562 YP_003031782.1 CDS TBMG_01827 NC_012943.1 2000253 2001827 D cell division protein ftsW 2000253..2001827 Mycobacterium tuberculosis KZN 1435 8161563 YP_003031783.1 CDS murG NC_012943.1 2001824 2003056 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 2001824..2003056 Mycobacterium tuberculosis KZN 1435 8161564 YP_003031784.1 CDS murC NC_012943.1 2003053 2004537 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2003053..2004537 Mycobacterium tuberculosis KZN 1435 8161565 YP_003031785.1 CDS TBMG_01830 NC_012943.1 2004534 2005478 D cell division protein ftsQ 2004534..2005478 Mycobacterium tuberculosis KZN 1435 8161566 YP_003031786.1 CDS TBMG_01831 NC_012943.1 2005651 2006790 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2005651..2006790 Mycobacterium tuberculosis KZN 1435 8161567 YP_003031787.1 CDS TBMG_01832 NC_012943.1 2006801 2007553 D hypothetical protein 2006801..2007553 Mycobacterium tuberculosis KZN 1435 8161649 YP_003031788.1 CDS TBMG_01833 NC_012943.1 2007550 2008335 D hypothetical protein 2007550..2008335 Mycobacterium tuberculosis KZN 1435 8161650 YP_003031789.1 CDS TBMG_01834 NC_012943.1 2008332 2009057 D hypothetical protein 2008332..2009057 Mycobacterium tuberculosis KZN 1435 8161651 YP_003031790.1 CDS TBMG_01835 NC_012943.1 2009219 2009509 D hypothetical protein 2009219..2009509 Mycobacterium tuberculosis KZN 1435 8161652 YP_003031791.1 CDS TBMG_01836 NC_012943.1 2009777 2010559 D hypothetical protein 2009777..2010559 Mycobacterium tuberculosis KZN 1435 8161653 YP_003031792.1 CDS TBMG_01837 NC_012943.1 2010654 2011010 D hypothetical protein 2010654..2011010 Mycobacterium tuberculosis KZN 1435 8161654 YP_003031793.1 CDS TBMG_01838 NC_012943.1 2011140 2012198 R hypothetical protein complement(2011140..2012198) Mycobacterium tuberculosis KZN 1435 8161655 YP_003031794.1 CDS TBMG_01839 NC_012943.1 2012453 2012668 D toxin 2012453..2012668 Mycobacterium tuberculosis KZN 1435 8161656 YP_003031795.1 CDS TBMG_01840 NC_012943.1 2012665 2012982 D toxin 2012665..2012982 Mycobacterium tuberculosis KZN 1435 8161657 YP_003031796.1 CDS TBMG_01841 NC_012943.1 2013389 2014741 D hypothetical protein 2013389..2014741 Mycobacterium tuberculosis KZN 1435 8161659 YP_003031797.1 CDS TBMG_01842 NC_012943.1 2014789 2015319 D hypothetical protein 2014789..2015319 Mycobacterium tuberculosis KZN 1435 8161660 YP_003031798.1 CDS TBMG_01843 NC_012943.1 2015324 2016397 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(2015324..2016397) Mycobacterium tuberculosis KZN 1435 8161661 YP_003031799.1 CDS TBMG_04037 NC_012943.1 2016433 2016714 R hypothetical protein complement(2016433..2016714) Mycobacterium tuberculosis KZN 1435 8161662 YP_003031800.1 CDS TBMG_04038 NC_012943.1 2016711 2017787 R hypothetical protein complement(2016711..2017787) Mycobacterium tuberculosis KZN 1435 8161663 YP_003031801.1 CDS TBMG_01844 NC_012943.1 2017802 2018215 D hypothetical protein 2017802..2018215 Mycobacterium tuberculosis KZN 1435 8161664 YP_003031802.1 CDS TBMG_01845 NC_012943.1 2018279 2019109 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 2018279..2019109 Mycobacterium tuberculosis KZN 1435 8161665 YP_003031803.1 CDS TBMG_01846 NC_012943.1 2019106 2019816 D hypothetical protein 2019106..2019816 Mycobacterium tuberculosis KZN 1435 8161666 YP_003031804.1 CDS TBMG_01847 NC_012943.1 2019880 2020467 D hypothetical protein 2019880..2020467 Mycobacterium tuberculosis KZN 1435 8161667 YP_003031805.1 CDS TBMG_01848 NC_012943.1 2020478 2021266 D hypothetical protein 2020478..2021266 Mycobacterium tuberculosis KZN 1435 8161668 YP_003031806.1 CDS TBMG_01849 NC_012943.1 2021476 2021706 R hypothetical protein complement(2021476..2021706) Mycobacterium tuberculosis KZN 1435 8161669 YP_003031807.1 CDS TBMG_01850 NC_012943.1 2021797 2022600 D monophosphatase cysQ 2021797..2022600 Mycobacterium tuberculosis KZN 1435 8161670 YP_003031808.1 CDS TBMG_01851 NC_012943.1 2022658 2023902 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2022658..2023902 Mycobacterium tuberculosis KZN 1435 8161671 YP_003031809.1 CDS TBMG_04039 NC_012943.1 2023928 2024809 D short chain dehydrogenase 2023928..2024809 Mycobacterium tuberculosis KZN 1435 8161672 YP_003031810.1 CDS TBMG_01852 NC_012943.1 2024829 2025032 R hypothetical protein complement(2024829..2025032) Mycobacterium tuberculosis KZN 1435 8161673 YP_003031811.1 CDS TBMG_01853 NC_012943.1 2025032 2026501 R L-asparagine permease ansP1 complement(2025032..2026501) Mycobacterium tuberculosis KZN 1435 8161674 YP_003031812.1 CDS TBMG_04040 NC_012943.1 2026882 2027148 D PE family protein 2026882..2027148 Mycobacterium tuberculosis KZN 1435 8161675 YP_003031813.1 CDS TBMG_04041 NC_012943.1 2027145 2027915 D PE-PGRS family protein 2027145..2027915 Mycobacterium tuberculosis KZN 1435 8161676 YP_003031814.1 CDS TBMG_01855 NC_012943.1 2027946 2028824 R hypothetical protein complement(2027946..2028824) Mycobacterium tuberculosis KZN 1435 8161677 YP_003031815.1 CDS TBMG_01856 NC_012943.1 2029050 2032628 D 5-methyltetrahydrofolate--homocysteine methyltransferase 2029050..2032628 Mycobacterium tuberculosis KZN 1435 8161678 YP_003031816.1 CDS TBMG_01857 NC_012943.1 2032554 2034044 R PPE family protein complement(2032554..2034044) Mycobacterium tuberculosis KZN 1435 8161679 YP_003031817.1 CDS hisE NC_012943.1 2034171 2034452 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2034171..2034452 Mycobacterium tuberculosis KZN 1435 8161680 YP_003031818.1 CDS hisG NC_012943.1 2034455 2035309 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2034455..2035309 Mycobacterium tuberculosis KZN 1435 8161681 YP_003031819.1 CDS TBMG_01860 NC_012943.1 2035355 2035870 D hypothetical protein 2035355..2035870 Mycobacterium tuberculosis KZN 1435 8161682 YP_003031820.1 CDS TBMG_01861 NC_012943.1 2035893 2036729 R hypothetical protein complement(2035893..2036729) Mycobacterium tuberculosis KZN 1435 8161683 YP_003031821.1 CDS TBMG_01862 NC_012943.1 2036803 2037645 D RNA methyltransferase 2036803..2037645 Mycobacterium tuberculosis KZN 1435 8161684 YP_003031822.1 CDS TBMG_01863 NC_012943.1 2037674 2037967 R hypothetical protein complement(2037674..2037967) Mycobacterium tuberculosis KZN 1435 8161685 YP_003031823.1 CDS TBMG_01864 NC_012943.1 2037975 2038544 R hypothetical protein complement(2037975..2038544) Mycobacterium tuberculosis KZN 1435 8161686 YP_003031824.1 CDS TBMG_01865 NC_012943.1 2038825 2040654 D ATPase 2038825..2040654 Mycobacterium tuberculosis KZN 1435 8161687 YP_003031825.1 CDS TBMG_01866 NC_012943.1 2040658 2041299 R hypothetical protein complement(2040658..2041299) Mycobacterium tuberculosis KZN 1435 8161688 YP_003031826.1 CDS TBMG_01867 NC_012943.1 2041292 2042485 R hypothetical protein complement(2041292..2042485) Mycobacterium tuberculosis KZN 1435 8161689 YP_003031827.1 CDS TBMG_01868 NC_012943.1 2042573 2044438 D hypothetical protein 2042573..2044438 Mycobacterium tuberculosis KZN 1435 8161690 YP_003031828.1 CDS TBMG_01869 NC_012943.1 2044530 2044745 D hypothetical protein 2044530..2044745 Mycobacterium tuberculosis KZN 1435 8161691 YP_003031829.1 CDS TBMG_01870 NC_012943.1 2044742 2045617 D proteasome beta subunit prcB 2044742..2045617 Mycobacterium tuberculosis KZN 1435 8161692 YP_003031830.1 CDS TBMG_01871 NC_012943.1 2045614 2046360 D proteasome alpha subunit prcA 2045614..2046360 Mycobacterium tuberculosis KZN 1435 8161693 YP_003031831.1 CDS TBMG_01872 NC_012943.1 2046900 2047631 R PPE family protein complement(2046900..2047631) Mycobacterium tuberculosis KZN 1435 8161694 YP_003031832.1 CDS TBMG_01873 NC_012943.1 2047687 2047983 R PE family protein complement(2047687..2047983) Mycobacterium tuberculosis KZN 1435 8161695 YP_003031833.1 CDS TBMG_01874 NC_012943.1 2048187 2048513 D transposase 2048187..2048513 Mycobacterium tuberculosis KZN 1435 8161696 YP_003031834.1 CDS TBMG_04042 NC_012943.1 2048564 2049448 D transposase 2048564..2049448 Mycobacterium tuberculosis KZN 1435 8161697 YP_003031835.1 CDS TBMG_04043 NC_012943.1 2049858 2050184 D transposase 2049858..2050184 Mycobacterium tuberculosis KZN 1435 8161698 YP_003031836.1 CDS TBMG_04044 NC_012943.1 2050235 2051119 D transposase 2050235..2051119 Mycobacterium tuberculosis KZN 1435 8161699 YP_003031837.1 CDS TBMG_01877 NC_012943.1 2051607 2051903 D hypothetical protein 2051607..2051903 Mycobacterium tuberculosis KZN 1435 8161700 YP_003031838.1 CDS TBMG_01878 NC_012943.1 2051919 2052173 D antitoxin 2051919..2052173 Mycobacterium tuberculosis KZN 1435 8161701 YP_003031839.1 CDS TBMG_01879 NC_012943.1 2052180 2052614 D toxin 2052180..2052614 Mycobacterium tuberculosis KZN 1435 8161702 YP_003031840.1 CDS TBMG_01880 NC_012943.1 2052593 2053426 R hypothetical protein complement(2052593..2053426) Mycobacterium tuberculosis KZN 1435 8161703 YP_003031841.1 CDS TBMG_01881 NC_012943.1 2053419 2055968 R helicase helZ complement(2053419..2055968) Mycobacterium tuberculosis KZN 1435 8161704 YP_003031842.1 CDS TBMG_01882 NC_012943.1 2056579 2058231 R hypothetical protein complement(2056579..2058231) Mycobacterium tuberculosis KZN 1435 8161705 YP_003031843.1 CDS TBMG_01883 NC_012943.1 2058414 2058713 D PE family protein 2058414..2058713 Mycobacterium tuberculosis KZN 1435 8161706 YP_003031844.1 CDS TBMG_01884 NC_012943.1 2058719 2059888 D PE-PGRS family protein 2058719..2059888 Mycobacterium tuberculosis KZN 1435 8161707 YP_003031845.1 CDS TBMG_01885 NC_012943.1 2059940 2061298 D hypothetical protein 2059940..2061298 Mycobacterium tuberculosis KZN 1435 8161708 YP_003031846.1 CDS TBMG_01886 NC_012943.1 2061307 2062305 D hypothetical protein 2061307..2062305 Mycobacterium tuberculosis KZN 1435 8161709 YP_003031847.1 CDS TBMG_01887 NC_012943.1 2062302 2063252 D hypothetical protein 2062302..2063252 Mycobacterium tuberculosis KZN 1435 8161710 YP_003031848.1 CDS tatA NC_012943.1 2063224 2063571 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 2063224..2063571 Mycobacterium tuberculosis KZN 1435 8161711 YP_003031849.1 CDS TBMG_01889 NC_012943.1 2063588 2064514 D hypothetical protein 2063588..2064514 Mycobacterium tuberculosis KZN 1435 8161712 YP_003031850.1 CDS TBMG_01890 NC_012943.1 2064631 2067351 D ATP-dependent DNA helicase helY 2064631..2067351 Mycobacterium tuberculosis KZN 1435 8161713 YP_003031851.1 CDS TBMG_01891 NC_012943.1 2067393 2068127 D hypothetical protein 2067393..2068127 Mycobacterium tuberculosis KZN 1435 8161714 YP_003031852.1 CDS TBMG_01892 NC_012943.1 2068131 2069312 R 5'-3' exonuclease complement(2068131..2069312) Mycobacterium tuberculosis KZN 1435 8161715 YP_003031853.1 CDS TBMG_01893 NC_012943.1 2069361 2070488 D dipeptidase pepE 2069361..2070488 Mycobacterium tuberculosis KZN 1435 8161716 YP_003031854.1 CDS TBMG_01894 NC_012943.1 2070505 2072274 R Ser/Thr protein kinase complement(2070505..2072274) Mycobacterium tuberculosis KZN 1435 8161717 YP_003031855.1 CDS TBMG_04045 NC_012943.1 2072461 2072691 R transposase complement(2072461..2072691) Mycobacterium tuberculosis KZN 1435 8161718 YP_003031856.1 CDS TBMG_01895 NC_012943.1 2072769 2073374 R transposase complement(2072769..2073374) Mycobacterium tuberculosis KZN 1435 8161719 YP_003031857.1 CDS TBMG_01896 NC_012943.1 2073353 2073658 R transposase complement(2073353..2073658) Mycobacterium tuberculosis KZN 1435 8161720 YP_003031858.1 CDS TBMG_01897 NC_012943.1 2073741 2074877 R hypothetical protein complement(2073741..2074877) Mycobacterium tuberculosis KZN 1435 8161721 YP_003031859.1 CDS TBMG_01898 NC_012943.1 2074870 2075814 R hypothetical protein complement(2074870..2075814) Mycobacterium tuberculosis KZN 1435 8161722 YP_003031860.1 CDS TBMG_01899 NC_012943.1 2075811 2077976 R hypothetical protein complement(2075811..2077976) Mycobacterium tuberculosis KZN 1435 8161723 YP_003031861.1 CDS TBMG_01900 NC_012943.1 2078172 2078645 D hypothetical protein 2078172..2078645 Mycobacterium tuberculosis KZN 1435 8161724 YP_003031862.1 CDS TBMG_01901 NC_012943.1 2078841 2079404 R hypothetical protein complement(2078841..2079404) Mycobacterium tuberculosis KZN 1435 8161725 YP_003031863.1 CDS TBMG_01902 NC_012943.1 2079385 2081355 R hypothetical protein complement(2079385..2081355) Mycobacterium tuberculosis KZN 1435 8161726 YP_003031864.1 CDS TBMG_04046 NC_012943.1 2081337 2081651 R hypothetical protein complement(2081337..2081651) Mycobacterium tuberculosis KZN 1435 8161727 YP_003031865.1 CDS TBMG_01903 NC_012943.1 2081688 2081858 D hypothetical protein 2081688..2081858 Mycobacterium tuberculosis KZN 1435 8161728 YP_003031866.1 CDS TBMG_01904 NC_012943.1 2082116 2082415 D hypothetical protein 2082116..2082415 Mycobacterium tuberculosis KZN 1435 8161729 YP_003031867.1 CDS TBMG_01905 NC_012943.1 2082416 2083387 D hypothetical protein 2082416..2083387 Mycobacterium tuberculosis KZN 1435 8161318 YP_003031868.1 CDS TBMG_04047 NC_012943.1 2083422 2083673 D hypothetical protein 2083422..2083673 Mycobacterium tuberculosis KZN 1435 8163625 YP_003031869.1 CDS TBMG_01906 NC_012943.1 2083831 2085294 D hypothetical protein 2083831..2085294 Mycobacterium tuberculosis KZN 1435 8163626 YP_003031870.1 CDS TBMG_01907 NC_012943.1 2085304 2085717 R hypothetical protein complement(2085304..2085717) Mycobacterium tuberculosis KZN 1435 8163627 YP_003031871.1 CDS TBMG_01908 NC_012943.1 2085747 2086496 D short-chain type dehydrogenase 2085747..2086496 Mycobacterium tuberculosis KZN 1435 8163628 YP_003031872.1 CDS TBMG_01909 NC_012943.1 2086564 2087736 D precorrin-6y methyltransferase cobL 2086564..2087736 Mycobacterium tuberculosis KZN 1435 8163629 YP_003031873.1 CDS TBMG_01910 NC_012943.1 2087733 2088488 D precorrin-4 C11-methyltransferase 2087733..2088488 Mycobacterium tuberculosis KZN 1435 8163630 YP_003031874.1 CDS TBMG_01911 NC_012943.1 2088485 2089219 D CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 2088485..2089219 Mycobacterium tuberculosis KZN 1435 8163631 YP_003031875.1 CDS TBMG_01912 NC_012943.1 2089209 2090144 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigC complement(2089209..2090144) Mycobacterium tuberculosis KZN 1435 8163632 YP_003031876.1 CDS TBMG_01913 NC_012943.1 2089901 2090824 D class A beta-lactamase blaC 2089901..2090824 Mycobacterium tuberculosis KZN 1435 8163634 YP_003031877.1 CDS TBMG_01914 NC_012943.1 2090840 2092063 D hypothetical protein 2090840..2092063 Mycobacterium tuberculosis KZN 1435 8163633 YP_003031878.1 CDS TBMG_01915 NC_012943.1 2092009 2093535 R bifunctional cobI-cobJ fusion protein complement(2092009..2093535) Mycobacterium tuberculosis KZN 1435 8163635 YP_003031879.1 CDS cobH NC_012943.1 2093532 2094158 R catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase complement(2093532..2094158) Mycobacterium tuberculosis KZN 1435 8163636 YP_003031880.1 CDS TBMG_01917 NC_012943.1 2094168 2095259 R cobalamin biosynthesis protein cobG complement(2094168..2095259) Mycobacterium tuberculosis KZN 1435 8163637 YP_003031881.1 CDS TBMG_01918 NC_012943.1 2095243 2095653 R toxin complement(2095243..2095653) Mycobacterium tuberculosis KZN 1435 8163638 YP_003031882.1 CDS TBMG_01919 NC_012943.1 2095646 2095879 R antitoxin complement(2095646..2095879) Mycobacterium tuberculosis KZN 1435 8163639 YP_003031883.1 CDS cobN NC_012943.1 2095957 2099541 D with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 2095957..2099541 Mycobacterium tuberculosis KZN 1435 8163640 YP_003031884.1 CDS TBMG_01921 NC_012943.1 2099617 2100030 D hypothetical protein 2099617..2100030 Mycobacterium tuberculosis KZN 1435 8163641 YP_003031885.1 CDS TBMG_01922 NC_012943.1 2100002 2101537 R hypothetical protein complement(2100002..2101537) Mycobacterium tuberculosis KZN 1435 8163642 YP_003031886.1 CDS rpmB NC_012943.1 2101650 2101886 D required for 70S ribosome assembly; 50S ribosomal protein L28 2101650..2101886 Mycobacterium tuberculosis KZN 1435 8163643 YP_003031887.1 CDS rpmG NC_012943.1 2101886 2102050 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2101886..2102050 Mycobacterium tuberculosis KZN 1435 8163644 YP_003031888.1 CDS rpsN NC_012943.1 2102052 2102357 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 2102052..2102357 Mycobacterium tuberculosis KZN 1435 8163645 YP_003031889.1 CDS TBMG_01926 NC_012943.1 2102358 2102624 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 2102358..2102624 Mycobacterium tuberculosis KZN 1435 8163646 YP_003031890.1 CDS TBMG_01927 NC_012943.1 2102873 2103586 R hypothetical protein complement(2102873..2103586) Mycobacterium tuberculosis KZN 1435 8163647 YP_003031891.1 CDS fxsA NC_012943.1 2103662 2104189 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 2103662..2104189 Mycobacterium tuberculosis KZN 1435 8163648 YP_003031892.1 CDS TBMG_01929 NC_012943.1 2104194 2105798 D hypothetical protein 2104194..2105798 Mycobacterium tuberculosis KZN 1435 8163649 YP_003031893.1 CDS TBMG_01930 NC_012943.1 2105791 2108580 D polyprenol-monophosphomannose synthase ppm1 2105791..2108580 Mycobacterium tuberculosis KZN 1435 8163650 YP_003031894.1 CDS TBMG_01931 NC_012943.1 2108555 2108890 R hypothetical protein complement(2108555..2108890) Mycobacterium tuberculosis KZN 1435 8163651 YP_003031895.1 CDS TBMG_01932 NC_012943.1 2109056 2109418 D hypothetical protein 2109056..2109418 Mycobacterium tuberculosis KZN 1435 8163652 YP_003031896.1 CDS TBMG_01933 NC_012943.1 2109725 2122183 D hypothetical protein 2109725..2122183 Mycobacterium tuberculosis KZN 1435 8163653 YP_003031897.1 CDS TBMG_01934 NC_012943.1 2122188 2124752 D hypothetical protein 2122188..2124752 Mycobacterium tuberculosis KZN 1435 8163654 YP_003031898.1 CDS TBMG_01935 NC_012943.1 2124789 2125445 R hypothetical protein complement(2124789..2125445) Mycobacterium tuberculosis KZN 1435 8163655 YP_003031899.1 CDS TBMG_01936 NC_012943.1 2125494 2127029 D carboxylesterase lipT 2125494..2127029 Mycobacterium tuberculosis KZN 1435 8163656 YP_003031900.1 CDS TBMG_01937 NC_012943.1 2127082 2127432 D hypothetical protein 2127082..2127432 Mycobacterium tuberculosis KZN 1435 8163657 YP_003031901.1 CDS TBMG_01938 NC_012943.1 2127473 2128033 D pyrazinamidase/nicotinamidas pncA 2127473..2128033 Mycobacterium tuberculosis KZN 1435 8163658 YP_003031902.1 CDS TBMG_01939 NC_012943.1 2128033 2128830 D hypothetical protein 2128033..2128830 Mycobacterium tuberculosis KZN 1435 8163659 YP_003031903.1 CDS TBMG_01940 NC_012943.1 2128868 2130187 D sugar-binding lipoprotein 2128868..2130187 Mycobacterium tuberculosis KZN 1435 8163660 YP_003031904.1 CDS TBMG_01941 NC_012943.1 2130184 2131086 D hypothetical protein 2130184..2131086 Mycobacterium tuberculosis KZN 1435 8163661 YP_003031905.1 CDS TBMG_01942 NC_012943.1 2131073 2131915 D hypothetical protein 2131073..2131915 Mycobacterium tuberculosis KZN 1435 8163662 YP_003031906.1 CDS TBMG_01943 NC_012943.1 2131918 2132991 D sugar ABC transporter 2131918..2132991 Mycobacterium tuberculosis KZN 1435 8163663 YP_003031907.1 CDS TBMG_01944 NC_012943.1 2132993 2133967 D hypothetical protein 2132993..2133967 Mycobacterium tuberculosis KZN 1435 8163664 YP_003031908.1 CDS TBMG_01945 NC_012943.1 2133974 2134615 R hypothetical protein complement(2133974..2134615) Mycobacterium tuberculosis KZN 1435 8163665 YP_003031909.1 CDS TBMG_01946 NC_012943.1 2134612 2135100 R hypothetical protein complement(2134612..2135100) Mycobacterium tuberculosis KZN 1435 8163666 YP_003031910.1 CDS TBMG_01947 NC_012943.1 2135097 2135567 R ArsR family transcriptional regulator complement(2135097..2135567) Mycobacterium tuberculosis KZN 1435 8163667 YP_003031911.1 CDS TBMG_01948 NC_012943.1 2135632 2136474 D hypothetical protein 2135632..2136474 Mycobacterium tuberculosis KZN 1435 8163668 YP_003031912.1 CDS TBMG_01949 NC_012943.1 2136590 2137585 R hypothetical protein complement(2136590..2137585) Mycobacterium tuberculosis KZN 1435 8163669 YP_003031913.1 CDS TBMG_01950 NC_012943.1 2137731 2138216 D heat shock protein hspX 2137731..2138216 Mycobacterium tuberculosis KZN 1435 8163670 YP_003031914.1 CDS TBMG_01951 NC_012943.1 2138228 2140273 D hypothetical protein 2138228..2140273 Mycobacterium tuberculosis KZN 1435 8163671 YP_003031915.1 CDS TBMG_01952 NC_012943.1 2140290 2141309 D phosphofructokinase pfkB 2140290..2141309 Mycobacterium tuberculosis KZN 1435 8163672 YP_003031916.1 CDS TBMG_01953 NC_012943.1 2141306 2142145 D hypothetical protein 2141306..2142145 Mycobacterium tuberculosis KZN 1435 8163673 YP_003031917.1 CDS TBMG_01954 NC_012943.1 2142206 2143927 D histidine kinase response regulator 2142206..2143927 Mycobacterium tuberculosis KZN 1435 8163674 YP_003031918.1 CDS TBMG_01955 NC_012943.1 2143967 2144851 D hypothetical protein 2143967..2144851 Mycobacterium tuberculosis KZN 1435 8163675 YP_003031919.1 CDS TBMG_01956 NC_012943.1 2144966 2145964 D hypothetical protein 2144966..2145964 Mycobacterium tuberculosis KZN 1435 8163676 YP_003031920.1 CDS TBMG_01957 NC_012943.1 2146474 2151294 D helicase 2146474..2151294 Mycobacterium tuberculosis KZN 1435 8163677 YP_003031921.1 CDS TBMG_01958 NC_012943.1 2151478 2152374 D hypothetical protein 2151478..2152374 Mycobacterium tuberculosis KZN 1435 8163678 YP_003031922.1 CDS TBMG_01959 NC_012943.1 2152769 2153446 D hypothetical protein 2152769..2153446 Mycobacterium tuberculosis KZN 1435 8163679 YP_003031923.1 CDS TBMG_01960 NC_012943.1 2153606 2153965 D hypothetical protein 2153606..2153965 Mycobacterium tuberculosis KZN 1435 8163680 YP_003031924.1 CDS TBMG_01961 NC_012943.1 2153990 2154595 D hypothetical protein 2153990..2154595 Mycobacterium tuberculosis KZN 1435 8163681 YP_003031925.1 CDS TBMG_01962 NC_012943.1 2154604 2154909 D transcriptional regulator 2154604..2154909 Mycobacterium tuberculosis KZN 1435 8163682 YP_003031926.1 CDS TBMG_01963 NC_012943.1 2154994 2155293 D hypothetical protein 2154994..2155293 Mycobacterium tuberculosis KZN 1435 8163683 YP_003031927.1 CDS TBMG_01964 NC_012943.1 2155309 2155611 R hypothetical protein complement(2155309..2155611) Mycobacterium tuberculosis KZN 1435 8163684 YP_003031928.1 CDS TBMG_01965 NC_012943.1 2155671 2156555 R transposase complement(2155671..2156555) Mycobacterium tuberculosis KZN 1435 8163685 YP_003031929.1 CDS TBMG_01966 NC_012943.1 2156606 2156932 R transposase complement(2156606..2156932) Mycobacterium tuberculosis KZN 1435 8163686 YP_003031930.1 CDS TBMG_01967 NC_012943.1 2157073 2157801 R hypothetical protein complement(2157073..2157801) Mycobacterium tuberculosis KZN 1435 8163687 YP_003031931.1 CDS TBMG_01968 NC_012943.1 2158034 2159074 R transcriptional regulator complement(2158034..2159074) Mycobacterium tuberculosis KZN 1435 8163688 YP_003031932.1 CDS TBMG_01969 NC_012943.1 2159071 2159682 R hypothetical protein complement(2159071..2159682) Mycobacterium tuberculosis KZN 1435 8163689 YP_003031933.1 CDS TBMG_01970 NC_012943.1 2160000 2161256 D hypothetical protein 2160000..2161256 Mycobacterium tuberculosis KZN 1435 8163690 YP_003031934.1 CDS TBMG_01971 NC_012943.1 2161384 2161974 R transposase complement(2161384..2161974) Mycobacterium tuberculosis KZN 1435 8163691 YP_003031935.1 CDS TBMG_01972 NC_012943.1 2161928 2162548 R transposase complement(2161928..2162548) Mycobacterium tuberculosis KZN 1435 8163692 YP_003031936.1 CDS TBMG_01973 NC_012943.1 2163007 2163255 R hypothetical protein complement(2163007..2163255) Mycobacterium tuberculosis KZN 1435 8163693 YP_003031937.1 CDS TBMG_01974 NC_012943.1 2163252 2163746 R hypothetical protein complement(2163252..2163746) Mycobacterium tuberculosis KZN 1435 8163694 YP_003031938.1 CDS TBMG_01975 NC_012943.1 2163787 2164218 D hypothetical protein 2163787..2164218 Mycobacterium tuberculosis KZN 1435 8163695 YP_003031939.1 CDS TBMG_01976 NC_012943.1 2164401 2164799 R toxin complement(2164401..2164799) Mycobacterium tuberculosis KZN 1435 8163696 YP_003031940.1 CDS TBMG_01977 NC_012943.1 2164800 2165042 R antitoxin complement(2164800..2165042) Mycobacterium tuberculosis KZN 1435 8163697 YP_003031941.1 CDS TBMG_01978 NC_012943.1 2165130 2166455 D hypothetical protein 2165130..2166455 Mycobacterium tuberculosis KZN 1435 8163698 YP_003031942.1 CDS TBMG_01979 NC_012943.1 2166644 2166988 D ferredoxin fdxA 2166644..2166988 Mycobacterium tuberculosis KZN 1435 8163699 YP_003031943.1 CDS TBMG_01980 NC_012943.1 2167087 2171070 R trehalose-6-phosphate phosphatase otsB1 complement(2167087..2171070) Mycobacterium tuberculosis KZN 1435 8163700 YP_003031944.1 CDS TBMG_01981 NC_012943.1 2171189 2172076 D hypothetical protein 2171189..2172076 Mycobacterium tuberculosis KZN 1435 8163701 YP_003031945.1 CDS TBMG_01982 NC_012943.1 2172098 2173594 D hypothetical protein 2172098..2173594 Mycobacterium tuberculosis KZN 1435 8163702 YP_003031946.1 CDS TBMG_01983 NC_012943.1 2173652 2174509 D hypothetical protein 2173652..2174509 Mycobacterium tuberculosis KZN 1435 8163703 YP_003031947.1 CDS TBMG_01984 NC_012943.1 2174630 2175412 R 20-beta-hydroxysteroid dehydrogenase complement(2174630..2175412) Mycobacterium tuberculosis KZN 1435 8163704 YP_003031948.1 CDS TBMG_01985 NC_012943.1 2175488 2176240 R hypothetical protein complement(2175488..2176240) Mycobacterium tuberculosis KZN 1435 8163705 YP_003031949.1 CDS TBMG_01986 NC_012943.1 2176250 2177863 R hypothetical protein complement(2176250..2177863) Mycobacterium tuberculosis KZN 1435 8161238 YP_003031950.1 CDS TBMG_01987 NC_012943.1 2177934 2179256 D hypothetical protein 2177934..2179256 Mycobacterium tuberculosis KZN 1435 8161239 YP_003031951.1 CDS TBMG_01988 NC_012943.1 2179351 2180127 D hypothetical protein 2179351..2180127 Mycobacterium tuberculosis KZN 1435 8161240 YP_003031952.1 CDS TBMG_01989 NC_012943.1 2180196 2182913 R metal cation transporting P-type ATPase ctpF complement(2180196..2182913) Mycobacterium tuberculosis KZN 1435 8161241 YP_003031953.1 CDS TBMG_01990 NC_012943.1 2183115 2184068 R hypothetical protein complement(2183115..2184068) Mycobacterium tuberculosis KZN 1435 8161242 YP_003031954.1 CDS TBMG_01991 NC_012943.1 2184164 2184931 R hypothetical protein complement(2184164..2184931) Mycobacterium tuberculosis KZN 1435 8161243 YP_003031955.1 CDS TBMG_01992 NC_012943.1 2185088 2185444 D transcriptional regulator 2185088..2185444 Mycobacterium tuberculosis KZN 1435 8161244 YP_003031956.1 CDS TBMG_01993 NC_012943.1 2185497 2185769 D hypothetical protein 2185497..2185769 Mycobacterium tuberculosis KZN 1435 8161245 YP_003031957.1 CDS TBMG_01994 NC_012943.1 2185766 2188081 D metal cation transporting P-type ATPase ctpG 2185766..2188081 Mycobacterium tuberculosis KZN 1435 8161246 YP_003031958.1 CDS TBMG_01995 NC_012943.1 2188181 2188429 D antitoxin 2188181..2188429 Mycobacterium tuberculosis KZN 1435 8161247 YP_003031959.1 CDS TBMG_01996 NC_012943.1 2188423 2188767 D toxin 2188423..2188767 Mycobacterium tuberculosis KZN 1435 8161248 YP_003031960.1 CDS TBMG_01997 NC_012943.1 2188856 2189191 D dehydrogenase 2188856..2189191 Mycobacterium tuberculosis KZN 1435 8161249 YP_003031961.1 CDS TBMG_01998 NC_012943.1 2189435 2189776 D transcriptional regulator 2189435..2189776 Mycobacterium tuberculosis KZN 1435 8161250 YP_003031962.1 CDS TBMG_01999 NC_012943.1 2189773 2190333 D hypothetical protein 2189773..2190333 Mycobacterium tuberculosis KZN 1435 8161251 YP_003031963.1 CDS TBMG_02000 NC_012943.1 2190853 2191392 R methyltransferase complement(2190853..2191392) Mycobacterium tuberculosis KZN 1435 8161252 YP_003031964.1 CDS TBMG_02001 NC_012943.1 2191618 2192046 R chitinase complement(2191618..2192046) Mycobacterium tuberculosis KZN 1435 8161253 YP_003031965.1 CDS TBMG_02002 NC_012943.1 2192462 2193061 R hypothetical protein complement(2192462..2193061) Mycobacterium tuberculosis KZN 1435 8161254 YP_003031966.1 CDS TBMG_02003 NC_012943.1 2193170 2194081 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 2193170..2194081 Mycobacterium tuberculosis KZN 1435 8161255 YP_003031967.1 CDS TBMG_02004 NC_012943.1 2194166 2194396 R PE-PGRS family protein complement(2194166..2194396) Mycobacterium tuberculosis KZN 1435 8161256 YP_003031968.1 CDS TBMG_02005 NC_012943.1 2194511 2195164 D cutinase precursor cfp21 2194511..2195164 Mycobacterium tuberculosis KZN 1435 8161257 YP_003031969.1 CDS TBMG_02006 NC_012943.1 2195152 2196828 R PE-PGRS family protein complement(2195152..2196828) Mycobacterium tuberculosis KZN 1435 8161258 YP_003031970.1 CDS TBMG_02007 NC_012943.1 2196971 2197231 D antitoxin 2196971..2197231 Mycobacterium tuberculosis KZN 1435 8161259 YP_003031971.1 CDS TBMG_02008 NC_012943.1 2197240 2197659 D toxin 2197240..2197659 Mycobacterium tuberculosis KZN 1435 8161260 YP_003031972.1 CDS nrdF1 NC_012943.1 2197884 2198852 D ribonucleotide-diphosphate reductase subunit beta 2197884..2198852 Mycobacterium tuberculosis KZN 1435 8161261 YP_003031973.1 CDS TBMG_02010 NC_012943.1 2199043 2199729 D hypothetical protein 2199043..2199729 Mycobacterium tuberculosis KZN 1435 8161262 YP_003031974.1 CDS TBMG_02011 NC_012943.1 2199908 2201353 D permease 2199908..2201353 Mycobacterium tuberculosis KZN 1435 8161263 YP_003031975.1 CDS TBMG_02012 NC_012943.1 2201316 2202164 R hypothetical protein complement(2201316..2202164) Mycobacterium tuberculosis KZN 1435 8161264 YP_003031976.1 CDS TBMG_02013 NC_012943.1 2202272 2203318 R hypothetical protein complement(2202272..2203318) Mycobacterium tuberculosis KZN 1435 8161265 YP_003031977.1 CDS TBMG_02014 NC_012943.1 2203821 2204228 D hypothetical protein 2203821..2204228 Mycobacterium tuberculosis KZN 1435 8161266 YP_003031978.1 CDS TBMG_02015 NC_012943.1 2204355 2204963 R hypothetical protein complement(2204355..2204963) Mycobacterium tuberculosis KZN 1435 8161267 YP_003031979.1 CDS TBMG_02016 NC_012943.1 2205036 2205413 R hypothetical protein complement(2205036..2205413) Mycobacterium tuberculosis KZN 1435 8161268 YP_003031980.1 CDS TBMG_02017 NC_012943.1 2205426 2205908 R hypothetical protein complement(2205426..2205908) Mycobacterium tuberculosis KZN 1435 8161269 YP_003031981.1 CDS TBMG_02018 NC_012943.1 2205905 2206480 R hypothetical protein complement(2205905..2206480) Mycobacterium tuberculosis KZN 1435 8161270 YP_003031982.1 CDS TBMG_02019 NC_012943.1 2206502 2207815 R MCE-family protein mce3F complement(2206502..2207815) Mycobacterium tuberculosis KZN 1435 8161271 YP_003031983.1 CDS TBMG_02020 NC_012943.1 2207816 2208949 R MCE-family lipoprotein mce3E complement(2207816..2208949) Mycobacterium tuberculosis KZN 1435 8161272 YP_003031984.1 CDS TBMG_02021 NC_012943.1 2208946 2210187 R MCE-family protein mce3D complement(2208946..2210187) Mycobacterium tuberculosis KZN 1435 8161273 YP_003031985.1 CDS TBMG_02022 NC_012943.1 2210214 2211458 R MCE-family protein mce3C complement(2210214..2211458) Mycobacterium tuberculosis KZN 1435 8161274 YP_003031986.1 CDS TBMG_02023 NC_012943.1 2211443 2212471 R MCE-family protein mce3B complement(2211443..2212471) Mycobacterium tuberculosis KZN 1435 8161275 YP_003031987.1 CDS TBMG_02024 NC_012943.1 2212468 2213745 R MCE-family protein mce3A complement(2212468..2213745) Mycobacterium tuberculosis KZN 1435 8161276 YP_003031988.1 CDS TBMG_02025 NC_012943.1 2213750 2214565 R hypothetical protein complement(2213750..2214565) Mycobacterium tuberculosis KZN 1435 8161277 YP_003031989.1 CDS TBMG_02026 NC_012943.1 2214575 2215384 R hypothetical protein complement(2214575..2215384) Mycobacterium tuberculosis KZN 1435 8161278 YP_003031990.1 CDS TBMG_02027 NC_012943.1 2215600 2216052 D hypothetical protein 2215600..2216052 Mycobacterium tuberculosis KZN 1435 8161279 YP_003031991.1 CDS TBMG_02028 NC_012943.1 2216271 2217491 D TetR family transcriptional regulator 2216271..2217491 Mycobacterium tuberculosis KZN 1435 8161280 YP_003031992.1 CDS TBMG_02029 NC_012943.1 2217524 2217796 D antitoxin 2217524..2217796 Mycobacterium tuberculosis KZN 1435 8161281 YP_003031993.1 CDS TBMG_02030 NC_012943.1 2217800 2218207 D toxin 2217800..2218207 Mycobacterium tuberculosis KZN 1435 8161282 YP_003031994.1 CDS TBMG_02031 NC_012943.1 2218367 2218861 R hypothetical protein complement(2218367..2218861) Mycobacterium tuberculosis KZN 1435 8161283 YP_003031995.1 CDS TBMG_02032 NC_012943.1 2218848 2219099 D antitoxin 2218848..2219099 Mycobacterium tuberculosis KZN 1435 8161285 YP_003031996.1 CDS TBMG_02033 NC_012943.1 2219096 2219392 D toxin 2219096..2219392 Mycobacterium tuberculosis KZN 1435 8161284 YP_003031997.1 CDS TBMG_02034 NC_012943.1 2219441 2220055 D hypothetical protein 2219441..2220055 Mycobacterium tuberculosis KZN 1435 8161286 YP_003031998.1 CDS TBMG_02035 NC_012943.1 2219944 2220489 R hypothetical protein complement(2219944..2220489) Mycobacterium tuberculosis KZN 1435 8161287 YP_003031999.1 CDS TBMG_02036 NC_012943.1 2220486 2220935 R antitoxin, transcriptional regulator complement(2220486..2220935) Mycobacterium tuberculosis KZN 1435 8161288 YP_003032000.1 CDS TBMG_02037 NC_012943.1 2220977 2221330 R toxin complement(2220977..2221330) Mycobacterium tuberculosis KZN 1435 8161289 YP_003032001.1 CDS TBMG_02039 NC_012943.1 2221824 2222135 R toxin complement(2221824..2222135) Mycobacterium tuberculosis KZN 1435 8161290 YP_003032002.1 CDS TBMG_02040 NC_012943.1 2222132 2222347 R antitoxin complement(2222132..2222347) Mycobacterium tuberculosis KZN 1435 8161291 YP_003032003.1 CDS TBMG_02041 NC_012943.1 2222587 2222883 D hypothetical protein 2222587..2222883 Mycobacterium tuberculosis KZN 1435 8161292 YP_003032004.1 CDS TBMG_02042 NC_012943.1 2222884 2223075 D hypothetical protein 2222884..2223075 Mycobacterium tuberculosis KZN 1435 8161293 YP_003032005.1 CDS TBMG_02043 NC_012943.1 2223096 2223998 D hypothetical protein 2223096..2223998 Mycobacterium tuberculosis KZN 1435 8161294 YP_003032006.1 CDS TBMG_02044 NC_012943.1 2224009 2224359 D hypothetical protein 2224009..2224359 Mycobacterium tuberculosis KZN 1435 8161295 YP_003032007.1 CDS TBMG_02045 NC_012943.1 2224648 2225049 R hypothetical protein complement(2224648..2225049) Mycobacterium tuberculosis KZN 1435 8161296 YP_003032008.1 CDS TBMG_02046 NC_012943.1 2225113 2225565 D hypothetical protein 2225113..2225565 Mycobacterium tuberculosis KZN 1435 8161297 YP_003032009.1 CDS TBMG_02047 NC_012943.1 2225720 2227168 R hypothetical protein complement(2225720..2227168) Mycobacterium tuberculosis KZN 1435 8161298 YP_003032010.1 CDS TBMG_02048 NC_012943.1 2227139 2227729 D hypothetical protein 2227139..2227729 Mycobacterium tuberculosis KZN 1435 8161300 YP_003032011.1 CDS TBMG_02049 NC_012943.1 2227726 2228103 D antitoxin 2227726..2228103 Mycobacterium tuberculosis KZN 1435 8161299 YP_003032012.1 CDS TBMG_02050 NC_012943.1 2228100 2228429 D toxin 2228100..2228429 Mycobacterium tuberculosis KZN 1435 8161301 YP_003032013.1 CDS TBMG_02051 NC_012943.1 2228639 2229409 R short-chain type dehydrogenase/reductase complement(2228639..2229409) Mycobacterium tuberculosis KZN 1435 8161302 YP_003032014.1 CDS TBMG_02052 NC_012943.1 2229406 2230467 R riboflavin biosynthesis protein ribA1 complement(2229406..2230467) Mycobacterium tuberculosis KZN 1435 8161303 YP_003032015.1 CDS TBMG_02053 NC_012943.1 2230464 2230979 R oxidoreductase complement(2230464..2230979) Mycobacterium tuberculosis KZN 1435 8161304 YP_003032016.1 CDS TBMG_02054 NC_012943.1 2230976 2232046 R epoxide hydrolase ephB complement(2230976..2232046) Mycobacterium tuberculosis KZN 1435 8161305 YP_003032017.1 CDS TBMG_02055 NC_012943.1 2232058 2234577 R oxygenase complement(2232058..2234577) Mycobacterium tuberculosis KZN 1435 8161306 YP_003032018.1 CDS TBMG_02056 NC_012943.1 2234580 2235689 R monooxygenase complement(2234580..2235689) Mycobacterium tuberculosis KZN 1435 8161307 YP_003032019.1 CDS TBMG_02057 NC_012943.1 2235914 2236870 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2235914..2236870 Mycobacterium tuberculosis KZN 1435 8161308 YP_003032020.1 CDS TBMG_02058 NC_012943.1 2236885 2238114 D acyl-CoA dehydrogenase 2236885..2238114 Mycobacterium tuberculosis KZN 1435 8161309 YP_003032021.1 CDS TBMG_02059 NC_012943.1 2238116 2239207 D acyl-CoA dehydrogenase 2238116..2239207 Mycobacterium tuberculosis KZN 1435 8161310 YP_003032022.1 CDS tpx NC_012943.1 2239204 2239701 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(2239204..2239701) Mycobacterium tuberculosis KZN 1435 8161311 YP_003032023.1 CDS TBMG_02061 NC_012943.1 2239822 2240613 D transcriptional regulator 2239822..2240613 Mycobacterium tuberculosis KZN 1435 8161312 YP_003032024.1 CDS TBMG_02062 NC_012943.1 2240631 2241155 D hypothetical protein 2240631..2241155 Mycobacterium tuberculosis KZN 1435 8161313 YP_003032025.1 CDS TBMG_02063 NC_012943.1 2241167 2241811 D hypothetical protein 2241167..2241811 Mycobacterium tuberculosis KZN 1435 8161314 YP_003032026.1 CDS TBMG_02064 NC_012943.1 2241856 2242623 D short chain dehydrogenase 2241856..2242623 Mycobacterium tuberculosis KZN 1435 8161315 YP_003032027.1 CDS TBMG_02065 NC_012943.1 2242627 2243400 R hypothetical protein complement(2242627..2243400) Mycobacterium tuberculosis KZN 1435 8161316 YP_003032028.1 CDS TBMG_02066 NC_012943.1 2243637 2244116 D hypothetical protein 2243637..2244116 Mycobacterium tuberculosis KZN 1435 8161317 YP_003032029.1 CDS TBMG_02067 NC_012943.1 2244124 2245986 R activates fatty acids by binding to coenzyme A; fatty-acid--CoA ligase complement(2244124..2245986) Mycobacterium tuberculosis KZN 1435 8163064 YP_003032030.1 CDS TBMG_02068 NC_012943.1 2246143 2246523 D hypothetical protein 2246143..2246523 Mycobacterium tuberculosis KZN 1435 8163065 YP_003032031.1 CDS TBMG_02069 NC_012943.1 2246560 2247900 R lipase lipD complement(2246560..2247900) Mycobacterium tuberculosis KZN 1435 8163066 YP_003032032.1 CDS TBMG_02070 NC_012943.1 2247891 2249006 R lipoprotein complement(2247891..2249006) Mycobacterium tuberculosis KZN 1435 8163067 YP_003032033.1 CDS TBMG_02071 NC_012943.1 2249278 2250549 D hypothetical protein 2249278..2250549 Mycobacterium tuberculosis KZN 1435 8163068 YP_003032034.1 CDS TBMG_02072 NC_012943.1 2250587 2251450 R hypothetical protein complement(2250587..2251450) Mycobacterium tuberculosis KZN 1435 8163069 YP_003032035.1 CDS TBMG_02073 NC_012943.1 2251548 2252012 D hypothetical protein 2251548..2252012 Mycobacterium tuberculosis KZN 1435 8163070 YP_003032036.1 CDS TBMG_02074 NC_012943.1 2252461 2255424 D PPE family protein 2252461..2255424 Mycobacterium tuberculosis KZN 1435 8163071 YP_003032037.1 CDS TBMG_02075 NC_012943.1 2255729 2259928 D PPE family protein 2255729..2259928 Mycobacterium tuberculosis KZN 1435 8163072 YP_003032038.1 CDS TBMG_02076 NC_012943.1 2260098 2261294 R isocitrate lyase aceAb complement(2260098..2261294) Mycobacterium tuberculosis KZN 1435 8163073 YP_003032039.1 CDS TBMG_02077 NC_012943.1 2261294 2262397 R isocitrate lyase aceAa complement(2261294..2262397) Mycobacterium tuberculosis KZN 1435 8163074 YP_003032040.1 CDS TBMG_02078 NC_012943.1 2262532 2262939 D hypothetical protein 2262532..2262939 Mycobacterium tuberculosis KZN 1435 8163075 YP_003032041.1 CDS TBMG_02079 NC_012943.1 2262917 2263669 R hypothetical protein complement(2262917..2263669) Mycobacterium tuberculosis KZN 1435 8163076 YP_003032042.1 CDS TBMG_02080 NC_012943.1 2263769 2264773 D oxidoreductase fadB5 2263769..2264773 Mycobacterium tuberculosis KZN 1435 8163077 YP_003032043.1 CDS TBMG_02081 NC_012943.1 2264861 2265478 D hypothetical protein 2264861..2265478 Mycobacterium tuberculosis KZN 1435 8163078 YP_003032044.1 CDS TBMG_02082 NC_012943.1 2265540 2266154 D hypothetical protein 2265540..2266154 Mycobacterium tuberculosis KZN 1435 8163079 YP_003032045.1 CDS TBMG_02083 NC_012943.1 2266259 2266711 D ferric uptake regulation protein furA 2266259..2266711 Mycobacterium tuberculosis KZN 1435 8163080 YP_003032046.1 CDS TBMG_02084 NC_012943.1 2266749 2268971 D catalase-peroxidase-peroxynitritase T katG 2266749..2268971 Mycobacterium tuberculosis KZN 1435 8163081 YP_003032047.1 CDS TBMG_02085 NC_012943.1 2268978 2269625 D hypothetical protein 2268978..2269625 Mycobacterium tuberculosis KZN 1435 8163082 YP_003032048.1 CDS TBMG_04048 NC_012943.1 2269677 2269907 D hypothetical protein 2269677..2269907 Mycobacterium tuberculosis KZN 1435 8163083 YP_003032049.1 CDS TBMG_02086 NC_012943.1 2269965 2270435 D hypothetical protein 2269965..2270435 Mycobacterium tuberculosis KZN 1435 8163084 YP_003032050.1 CDS TBMG_02087 NC_012943.1 2270465 2271427 D D-amino acid oxidase aao 2270465..2271427 Mycobacterium tuberculosis KZN 1435 8163085 YP_003032051.1 CDS TBMG_02088 NC_012943.1 2271475 2271906 R hypothetical protein complement(2271475..2271906) Mycobacterium tuberculosis KZN 1435 8163086 YP_003032052.1 CDS TBMG_02089 NC_012943.1 2272092 2272496 R hypothetical protein complement(2272092..2272496) Mycobacterium tuberculosis KZN 1435 8163087 YP_003032053.1 CDS TBMG_02090 NC_012943.1 2272586 2273854 D hypothetical protein 2272586..2273854 Mycobacterium tuberculosis KZN 1435 8163088 YP_003032054.1 CDS TBMG_02091 NC_012943.1 2273906 2275198 R competence damage-inducible protein A complement(2273906..2275198) Mycobacterium tuberculosis KZN 1435 8163089 YP_003032055.1 CDS TBMG_04049 NC_012943.1 2275227 2276615 D lignin peroxidase lipJ 2275227..2276615 Mycobacterium tuberculosis KZN 1435 8163090 YP_003032056.1 CDS TBMG_04050 NC_012943.1 2276567 2277691 D hypothetical protein 2276567..2277691 Mycobacterium tuberculosis KZN 1435 8163091 YP_003032057.1 CDS TBMG_02094 NC_012943.1 2277657 2277965 R hypothetical protein complement(2277657..2277965) Mycobacterium tuberculosis KZN 1435 8163092 YP_003032058.1 CDS TBMG_02095 NC_012943.1 2278023 2278454 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2278023..2278454 Mycobacterium tuberculosis KZN 1435 8163093 YP_003032059.1 CDS TBMG_02096 NC_012943.1 2278459 2279370 D hypothetical protein 2278459..2279370 Mycobacterium tuberculosis KZN 1435 8163094 YP_003032060.1 CDS TBMG_02097 NC_012943.1 2279230 2280384 R dehydrogenase complement(2279230..2280384) Mycobacterium tuberculosis KZN 1435 8163095 YP_003032061.1 CDS TBMG_02098 NC_012943.1 2280532 2280963 R hypothetical protein complement(2280532..2280963) Mycobacterium tuberculosis KZN 1435 8163096 YP_003032062.1 CDS TBMG_02099 NC_012943.1 2281036 2282166 D hypothetical protein 2281036..2282166 Mycobacterium tuberculosis KZN 1435 8163097 YP_003032063.1 CDS TBMG_02100 NC_012943.1 2282201 2282419 R hypothetical protein complement(2282201..2282419) Mycobacterium tuberculosis KZN 1435 8163098 YP_003032064.1 CDS TBMG_02101 NC_012943.1 2282429 2282740 R hypothetical protein complement(2282429..2282740) Mycobacterium tuberculosis KZN 1435 8163099 YP_003032065.1 CDS TBMG_02102 NC_012943.1 2282757 2283164 R hypothetical protein complement(2282757..2283164) Mycobacterium tuberculosis KZN 1435 8163100 YP_003032066.1 CDS TBMG_02103 NC_012943.1 2283218 2283829 D hypothetical protein 2283218..2283829 Mycobacterium tuberculosis KZN 1435 8163101 YP_003032067.1 CDS TBMG_02104 NC_012943.1 2283888 2284244 D methyltransferase 2283888..2284244 Mycobacterium tuberculosis KZN 1435 8163102 YP_003032068.1 CDS TBMG_02105 NC_012943.1 2284288 2284461 D hypothetical protein 2284288..2284461 Mycobacterium tuberculosis KZN 1435 8163103 YP_003032069.1 CDS TBMG_02106 NC_012943.1 2284787 2285545 D hypothetical protein 2284787..2285545 Mycobacterium tuberculosis KZN 1435 8163104 YP_003032070.1 CDS TBMG_02107 NC_012943.1 2285515 2286657 R hypothetical protein complement(2285515..2286657) Mycobacterium tuberculosis KZN 1435 8163105 YP_003032071.1 CDS TBMG_02108 NC_012943.1 2287048 2288025 D secreted fibronectin-binding protein antigen 85-B fbpB 2287048..2288025 Mycobacterium tuberculosis KZN 1435 8163106 YP_003032072.1 CDS TBMG_02109 NC_012943.1 2288043 2288642 D catalyzes the interconversion of chorismate to prephenate; chorismate mutase 2288043..2288642 Mycobacterium tuberculosis KZN 1435 8163107 YP_003032073.1 CDS TBMG_02110 NC_012943.1 2288654 2289184 D resuscitation-promoting factor rpfC 2288654..2289184 Mycobacterium tuberculosis KZN 1435 8163108 YP_003032074.1 CDS TBMG_02111 NC_012943.1 2289223 2289699 D hypothetical protein 2289223..2289699 Mycobacterium tuberculosis KZN 1435 8163109 YP_003032075.1 CDS TBMG_02112 NC_012943.1 2289727 2290560 D short chain dehydrogenase 2289727..2290560 Mycobacterium tuberculosis KZN 1435 8163110 YP_003032076.1 CDS TBMG_02113 NC_012943.1 2290601 2291023 D hypothetical protein 2290601..2291023 Mycobacterium tuberculosis KZN 1435 8163111 YP_003032077.1 CDS TBMG_02114 NC_012943.1 2291073 2292389 D cytochrome P450 140 cyp140 2291073..2292389 Mycobacterium tuberculosis KZN 1435 8163112 YP_003032078.1 CDS TBMG_02115 NC_012943.1 2292417 2293553 R hypothetical protein complement(2292417..2293553) Mycobacterium tuberculosis KZN 1435 8163113 YP_003032079.1 CDS TBMG_02116 NC_012943.1 2293556 2294908 R glutamine synthetase glnA3 complement(2293556..2294908) Mycobacterium tuberculosis KZN 1435 8163114 YP_003032080.1 CDS TBMG_02117 NC_012943.1 2294963 2297026 R hypothetical protein complement(2294963..2297026) Mycobacterium tuberculosis KZN 1435 8163115 YP_003032081.1 CDS TBMG_02118 NC_012943.1 2297111 2297590 R bacterioferritin bfrA complement(2297111..2297590) Mycobacterium tuberculosis KZN 1435 8163116 YP_003032082.1 CDS TBMG_02119 NC_012943.1 2298106 2298549 R hypothetical protein complement(2298106..2298549) Mycobacterium tuberculosis KZN 1435 8163117 YP_003032083.1 CDS TBMG_02120 NC_012943.1 2298560 2299264 R hypothetical protein complement(2298560..2299264) Mycobacterium tuberculosis KZN 1435 8163118 YP_003032084.1 CDS TBMG_02121 NC_012943.1 2299319 2299756 R hypothetical protein complement(2299319..2299756) Mycobacterium tuberculosis KZN 1435 8163119 YP_003032085.1 CDS TBMG_02122 NC_012943.1 2299779 2301023 D L-lactate dehydrogenase lldD2 2299779..2301023 Mycobacterium tuberculosis KZN 1435 8163120 YP_003032086.1 CDS TBMG_02123 NC_012943.1 2301046 2301435 D hypothetical protein 2301046..2301435 Mycobacterium tuberculosis KZN 1435 8163121 YP_003032087.1 CDS TBMG_02124 NC_012943.1 2301500 2302135 D hypothetical protein 2301500..2302135 Mycobacterium tuberculosis KZN 1435 8163122 YP_003032088.1 CDS TBMG_02125 NC_012943.1 2302235 2303470 D reductase 2302235..2303470 Mycobacterium tuberculosis KZN 1435 8163123 YP_003032089.1 CDS TBMG_02126 NC_012943.1 2303484 2305583 R hypothetical protein complement(2303484..2305583) Mycobacterium tuberculosis KZN 1435 8163124 YP_003032090.1 CDS TBMG_02127 NC_012943.1 2305682 2307166 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(2305682..2307166) Mycobacterium tuberculosis KZN 1435 8163125 YP_003032091.1 CDS TBMG_02128 NC_012943.1 2307454 2309862 R hypothetical protein complement(2307454..2309862) Mycobacterium tuberculosis KZN 1435 8163126 YP_003032092.1 CDS TBMG_02129 NC_012943.1 2309964 2310824 D short chain dehydrogenase 2309964..2310824 Mycobacterium tuberculosis KZN 1435 8163127 YP_003032093.1 CDS TBMG_02130 NC_012943.1 2310821 2311576 D hypothetical protein 2310821..2311576 Mycobacterium tuberculosis KZN 1435 8163128 YP_003032094.1 CDS TBMG_02131 NC_012943.1 2311569 2312339 D hypothetical protein 2311569..2312339 Mycobacterium tuberculosis KZN 1435 8163129 YP_003032095.1 CDS TBMG_02132 NC_012943.1 2312346 2313386 R alcohol dehydrogenase complement(2312346..2313386) Mycobacterium tuberculosis KZN 1435 8163130 YP_003032096.1 CDS TBMG_02133 NC_012943.1 2313461 2313766 R hypothetical protein complement(2313461..2313766) Mycobacterium tuberculosis KZN 1435 8163131 YP_003032097.1 CDS TBMG_02134 NC_012943.1 2314218 2315195 R hypothetical protein complement(2314218..2315195) Mycobacterium tuberculosis KZN 1435 8163132 YP_003032098.1 CDS TBMG_02135 NC_012943.1 2315248 2316357 R molybdenum-transport ATP-binding protein ABC transporter modC complement(2315248..2316357) Mycobacterium tuberculosis KZN 1435 8163133 YP_003032099.1 CDS TBMG_02136 NC_012943.1 2316364 2317158 R hypothetical protein complement(2316364..2317158) Mycobacterium tuberculosis KZN 1435 8163134 YP_003032100.1 CDS TBMG_02137 NC_012943.1 2317161 2317946 R molybdate-binding lipoprotein modA complement(2317161..2317946) Mycobacterium tuberculosis KZN 1435 8163135 YP_003032101.1 CDS TBMG_02138 NC_012943.1 2318108 2318785 D short chain dehydrogenase 2318108..2318785 Mycobacterium tuberculosis KZN 1435 8163136 YP_003032102.1 CDS TBMG_02139 NC_012943.1 2318824 2319747 D oxidoreductase 2318824..2319747 Mycobacterium tuberculosis KZN 1435 8163137 YP_003032103.1 CDS TBMG_02140 NC_012943.1 2319889 2321280 D NADH dehydrogenase ndh 2319889..2321280 Mycobacterium tuberculosis KZN 1435 8163138 YP_003032104.1 CDS TBMG_02141 NC_012943.1 2321283 2321927 R urease accessory protein ureD complement(2321283..2321927) Mycobacterium tuberculosis KZN 1435 8163139 YP_003032105.1 CDS TBMG_02142 NC_012943.1 2321917 2322591 R urease accessory protein ureG complement(2321917..2322591) Mycobacterium tuberculosis KZN 1435 8163140 YP_003032106.1 CDS TBMG_02143 NC_012943.1 2322602 2323237 R urease accessory protein ureF complement(2322602..2323237) Mycobacterium tuberculosis KZN 1435 8163141 YP_003032107.1 CDS ureC NC_012943.1 2323237 2324970 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(2323237..2324970) Mycobacterium tuberculosis KZN 1435 8163142 YP_003032108.1 CDS ureB NC_012943.1 2324970 2325284 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); urease subunit beta complement(2324970..2325284) Mycobacterium tuberculosis KZN 1435 8163461 YP_003032109.1 CDS ureA NC_012943.1 2325281 2325601 R UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma complement(2325281..2325601) Mycobacterium tuberculosis KZN 1435 8163462 YP_003032110.1 CDS TBMG_02147 NC_012943.1 2325632 2326054 R hypothetical protein complement(2325632..2326054) Mycobacterium tuberculosis KZN 1435 8163463 YP_003032111.1 CDS TBMG_02148 NC_012943.1 2326332 2326748 D transcriptional regulator 2326332..2326748 Mycobacterium tuberculosis KZN 1435 8163464 YP_003032112.1 CDS TBMG_02149 NC_012943.1 2326763 2327713 D hypothetical protein 2326763..2327713 Mycobacterium tuberculosis KZN 1435 8163465 YP_003032113.1 CDS TBMG_02150 NC_012943.1 2327743 2329194 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2327743..2329194 Mycobacterium tuberculosis KZN 1435 8163466 YP_003032114.1 CDS TBMG_02151 NC_012943.1 2329227 2330666 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 2329227..2330666 Mycobacterium tuberculosis KZN 1435 8163467 YP_003032115.1 CDS TBMG_02152 NC_012943.1 2330840 2332207 D hypothetical protein 2330840..2332207 Mycobacterium tuberculosis KZN 1435 8163468 YP_003032116.1 CDS TBMG_02153 NC_012943.1 2332207 2333244 D hypothetical protein 2332207..2333244 Mycobacterium tuberculosis KZN 1435 8163469 YP_003032117.1 CDS TBMG_02154 NC_012943.1 2333407 2334954 D PE-PGRS family protein 2333407..2334954 Mycobacterium tuberculosis KZN 1435 8163470 YP_003032118.1 CDS TBMG_02155 NC_012943.1 2335013 2335276 D antitoxin 2335013..2335276 Mycobacterium tuberculosis KZN 1435 8163471 YP_003032119.1 CDS TBMG_02156 NC_012943.1 2335273 2335668 D toxin 2335273..2335668 Mycobacterium tuberculosis KZN 1435 8163472 YP_003032120.1 CDS TBMG_02157 NC_012943.1 2335962 2338169 D catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 2335962..2338169 Mycobacterium tuberculosis KZN 1435 8163473 YP_003032121.1 CDS TBMG_04051 NC_012943.1 2338166 2338366 R hypothetical protein complement(2338166..2338366) Mycobacterium tuberculosis KZN 1435 8163474 YP_003032122.1 CDS TBMG_02158 NC_012943.1 2338289 2340322 D hypothetical protein 2338289..2340322 Mycobacterium tuberculosis KZN 1435 8163476 YP_003032123.1 CDS TBMG_02159 NC_012943.1 2340338 2342224 D hypothetical protein 2340338..2342224 Mycobacterium tuberculosis KZN 1435 8163475 YP_003032124.1 CDS TBMG_02160 NC_012943.1 2342229 2343095 R hydrolase complement(2342229..2343095) Mycobacterium tuberculosis KZN 1435 8163477 YP_003032125.1 CDS TBMG_02161 NC_012943.1 2343136 2343996 D haloalkane dehalogenase 2343136..2343996 Mycobacterium tuberculosis KZN 1435 8163478 YP_003032126.1 CDS TBMG_02162 NC_012943.1 2344223 2347048 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(2344223..2347048) Mycobacterium tuberculosis KZN 1435 8163479 YP_003032127.1 CDS TBMG_02163 NC_012943.1 2347407 2348084 R hypothetical protein complement(2347407..2348084) Mycobacterium tuberculosis KZN 1435 8163480 YP_003032128.1 CDS TBMG_02164 NC_012943.1 2348432 2348926 R hypothetical protein complement(2348432..2348926) Mycobacterium tuberculosis KZN 1435 8163481 YP_003032129.1 CDS TBMG_02165 NC_012943.1 2349045 2349788 R hypothetical protein complement(2349045..2349788) Mycobacterium tuberculosis KZN 1435 8163482 YP_003032130.1 CDS TBMG_02166 NC_012943.1 2349785 2350273 R hypothetical protein complement(2349785..2350273) Mycobacterium tuberculosis KZN 1435 8163483 YP_003032131.1 CDS TBMG_02167 NC_012943.1 2350513 2350917 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(2350513..2350917) Mycobacterium tuberculosis KZN 1435 8163484 YP_003032132.1 CDS TBMG_02168 NC_012943.1 2350955 2351833 R hypothetical protein complement(2350955..2351833) Mycobacterium tuberculosis KZN 1435 8163485 YP_003032133.1 CDS TBMG_02169 NC_012943.1 2351850 2352215 R hypothetical protein complement(2351850..2352215) Mycobacterium tuberculosis KZN 1435 8163486 YP_003032134.1 CDS TBMG_02170 NC_012943.1 2352244 2353173 R hypothetical protein complement(2352244..2353173) Mycobacterium tuberculosis KZN 1435 8163487 YP_003032135.1 CDS TBMG_02171 NC_012943.1 2353160 2353789 R CDP-diacylglycerol-glycerol-3-phosphate-3- phosphatidyltransferase pgsA2 complement(2353160..2353789) Mycobacterium tuberculosis KZN 1435 8163488 YP_003032136.1 CDS TBMG_02172 NC_012943.1 2353986 2356412 R SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(2353986..2356412) Mycobacterium tuberculosis KZN 1435 8163489 YP_003032137.1 CDS TBMG_02173 NC_012943.1 2356427 2358070 R hypothetical protein complement(2356427..2358070) Mycobacterium tuberculosis KZN 1435 8163490 YP_003032138.1 CDS TBMG_02174 NC_012943.1 2358141 2360060 D drugs-transport transmembrane ATP-binding protein ABC transporter 2358141..2360060 Mycobacterium tuberculosis KZN 1435 8163491 YP_003032139.1 CDS TBMG_04052 NC_012943.1 2360135 2361691 D PE-PGRS family protein 2360135..2361691 Mycobacterium tuberculosis KZN 1435 8163492 YP_003032140.1 CDS TBMG_02177 NC_012943.1 2361811 2363274 R hypothetical protein complement(2361811..2363274) Mycobacterium tuberculosis KZN 1435 8163493 YP_003032141.1 CDS TBMG_02178 NC_012943.1 2363909 2364613 R transcriptional regulator complement(2363909..2364613) Mycobacterium tuberculosis KZN 1435 8163494 YP_003032142.1 CDS TBMG_02179 NC_012943.1 2364676 2365341 R hypothetical protein complement(2364676..2365341) Mycobacterium tuberculosis KZN 1435 8163495 YP_003032143.1 CDS TBMG_02180 NC_012943.1 2365446 2366390 R membrane-bound C-5 sterol desaturase erg3 complement(2365446..2366390) Mycobacterium tuberculosis KZN 1435 8163496 YP_003032144.1 CDS TBMG_02181 NC_012943.1 2366757 2367188 D hypothetical protein 2366757..2367188 Mycobacterium tuberculosis KZN 1435 8163497 YP_003032145.1 CDS TBMG_02182 NC_012943.1 2367510 2368712 D dehydrogenase 2367510..2368712 Mycobacterium tuberculosis KZN 1435 8163498 YP_003032146.1 CDS TBMG_02183 NC_012943.1 2368722 2369426 R Mg2+ transport ATPase C mgtC complement(2368722..2369426) Mycobacterium tuberculosis KZN 1435 8163499 YP_003032147.1 CDS TBMG_02184 NC_012943.1 2369580 2369936 R hypothetical protein complement(2369580..2369936) Mycobacterium tuberculosis KZN 1435 8163500 YP_003032148.1 CDS TBMG_02185 NC_012943.1 2370181 2371593 R PPE family protein complement(2370181..2371593) Mycobacterium tuberculosis KZN 1435 8163501 YP_003032149.1 CDS TBMG_02186 NC_012943.1 2371719 2372951 R PPE family protein complement(2371719..2372951) Mycobacterium tuberculosis KZN 1435 8163502 YP_003032150.1 CDS TBMG_02187 NC_012943.1 2373272 2374483 R PPE family protein complement(2373272..2374483) Mycobacterium tuberculosis KZN 1435 8163503 YP_003032151.1 CDS TBMG_02188 NC_012943.1 2374498 2374797 R PE family protein complement(2374498..2374797) Mycobacterium tuberculosis KZN 1435 8163504 YP_003032152.1 CDS TBMG_02189 NC_012943.1 2374835 2375182 D hypothetical protein 2374835..2375182 Mycobacterium tuberculosis KZN 1435 8163505 YP_003032153.1 CDS TBMG_02190 NC_012943.1 2375553 2375879 D transposase 2375553..2375879 Mycobacterium tuberculosis KZN 1435 8163506 YP_003032154.1 CDS TBMG_02191 NC_012943.1 2375930 2376814 D transposase 2375930..2376814 Mycobacterium tuberculosis KZN 1435 8163507 YP_003032155.1 CDS TBMG_02192 NC_012943.1 2376878 2377204 D hypothetical protein 2376878..2377204 Mycobacterium tuberculosis KZN 1435 8163508 YP_003032156.1 CDS TBMG_02193 NC_012943.1 2377352 2379304 D PE-PGRS family protein 2377352..2379304 Mycobacterium tuberculosis KZN 1435 8163509 YP_003032157.1 CDS TBMG_02194 NC_012943.1 2379452 2380843 R PPE family protein complement(2379452..2380843) Mycobacterium tuberculosis KZN 1435 8163510 YP_003032158.1 CDS TBMG_02195 NC_012943.1 2380955 2382226 R PPE family protein complement(2380955..2382226) Mycobacterium tuberculosis KZN 1435 8163511 YP_003032159.1 CDS TBMG_02196 NC_012943.1 2382807 2384774 R PPE family protein complement(2382807..2384774) Mycobacterium tuberculosis KZN 1435 8163512 YP_003032160.1 CDS TBMG_02197 NC_012943.1 2384877 2385068 R hypothetical protein complement(2384877..2385068) Mycobacterium tuberculosis KZN 1435 8163513 YP_003032161.1 CDS TBMG_02198 NC_012943.1 2385695 2387527 R hypothetical protein complement(2385695..2387527) Mycobacterium tuberculosis KZN 1435 8163514 YP_003032162.1 CDS TBMG_02199 NC_012943.1 2387524 2388744 R hypothetical protein complement(2387524..2388744) Mycobacterium tuberculosis KZN 1435 8163515 YP_003032163.1 CDS TBMG_02200 NC_012943.1 2388741 2390498 R hypothetical protein complement(2388741..2390498) Mycobacterium tuberculosis KZN 1435 8163516 YP_003032164.1 CDS TBMG_02201 NC_012943.1 2390476 2391987 R hypothetical protein complement(2390476..2391987) Mycobacterium tuberculosis KZN 1435 8163517 YP_003032165.1 CDS TBMG_02202 NC_012943.1 2392259 2393161 R hypothetical protein complement(2392259..2393161) Mycobacterium tuberculosis KZN 1435 8163518 YP_003032166.1 CDS TBMG_02203 NC_012943.1 2393249 2393533 R esat-6 like protein esxN complement(2393249..2393533) Mycobacterium tuberculosis KZN 1435 8163519 YP_003032167.1 CDS TBMG_04053 NC_012943.1 2393584 2393703 R esat-6 like protein esxM complement(2393584..2393703) Mycobacterium tuberculosis KZN 1435 8163520 YP_003032168.1 CDS TBMG_02204 NC_012943.1 2393704 2393865 R esat-6 like protein esxM complement(2393704..2393865) Mycobacterium tuberculosis KZN 1435 8163521 YP_003032169.1 CDS TBMG_02205 NC_012943.1 2394024 2394341 R PE family protein complement(2394024..2394341) Mycobacterium tuberculosis KZN 1435 8163522 YP_003032170.1 CDS TBMG_02206 NC_012943.1 2394750 2395841 R PPE family protein complement(2394750..2395841) Mycobacterium tuberculosis KZN 1435 8163523 YP_003032171.1 CDS TBMG_02207 NC_012943.1 2395914 2396216 R hypothetical protein complement(2395914..2396216) Mycobacterium tuberculosis KZN 1435 8163524 YP_003032172.1 CDS TBMG_02208 NC_012943.1 2396256 2397437 R PPE family protein complement(2396256..2397437) Mycobacterium tuberculosis KZN 1435 8163525 YP_003032173.1 CDS TBMG_02209 NC_012943.1 2397451 2397750 R PE family protein complement(2397451..2397750) Mycobacterium tuberculosis KZN 1435 8163526 YP_003032174.1 CDS TBMG_02210 NC_012943.1 2397829 2399046 R PPE family protein complement(2397829..2399046) Mycobacterium tuberculosis KZN 1435 8163527 YP_003032175.1 CDS TBMG_02211 NC_012943.1 2399196 2399399 R ferredoxin complement(2399196..2399399) Mycobacterium tuberculosis KZN 1435 8163528 YP_003032176.1 CDS TBMG_02212 NC_012943.1 2399599 2400780 D cytochrome P450 143 cyp143 2399599..2400780 Mycobacterium tuberculosis KZN 1435 8163529 YP_003032177.1 CDS TBMG_02213 NC_012943.1 2400795 2404970 R FtsK/SpoIIIE family protein complement(2400795..2404970) Mycobacterium tuberculosis KZN 1435 8163530 YP_003032178.1 CDS TBMG_02214 NC_012943.1 2404967 2406487 R hypothetical protein complement(2404967..2406487) Mycobacterium tuberculosis KZN 1435 8163531 YP_003032179.1 CDS TBMG_02215 NC_012943.1 2406751 2408109 D truncated CDS; 4-alpha-glucanotransferase 2406751..2408109 Mycobacterium tuberculosis KZN 1435 8163532 YP_003032180.1 CDS TBMG_02216 NC_012943.1 2408966 2409529 R hypothetical protein complement(2408966..2409529) Mycobacterium tuberculosis KZN 1435 8163533 YP_003032181.1 CDS TBMG_04054 NC_012943.1 2409749 2411542 D hypothetical protein 2409749..2411542 Mycobacterium tuberculosis KZN 1435 8163534 YP_003032182.1 CDS TBMG_02217 NC_012943.1 2411641 2412147 D hypothetical protein 2411641..2412147 Mycobacterium tuberculosis KZN 1435 8163535 YP_003032183.1 CDS TBMG_02218 NC_012943.1 2412268 2413572 R cytochrome P450 144 cyp144 complement(2412268..2413572) Mycobacterium tuberculosis KZN 1435 8163536 YP_003032184.1 CDS TBMG_02219 NC_012943.1 2413673 2414233 D transcriptional regulator 2413673..2414233 Mycobacterium tuberculosis KZN 1435 8163537 YP_003032185.1 CDS TBMG_02220 NC_012943.1 2414238 2415056 R hypothetical protein complement(2414238..2415056) Mycobacterium tuberculosis KZN 1435 8163538 YP_003032186.1 CDS TBMG_02221 NC_012943.1 2415056 2416396 R oxidoreductase complement(2415056..2416396) Mycobacterium tuberculosis KZN 1435 8163539 YP_003032187.1 CDS TBMG_02222 NC_012943.1 2416462 2417208 D transcriptional regulator 2416462..2417208 Mycobacterium tuberculosis KZN 1435 8163540 YP_003032188.1 CDS TBMG_02223 NC_012943.1 2417281 2417592 R hypothetical protein complement(2417281..2417592) Mycobacterium tuberculosis KZN 1435 8163541 YP_003032189.1 CDS TBMG_02224 NC_012943.1 2417781 2419067 R oxidoreductase complement(2417781..2419067) Mycobacterium tuberculosis KZN 1435 8162051 YP_003032190.1 CDS TBMG_02225 NC_012943.1 2419064 2420350 R hypothetical protein complement(2419064..2420350) Mycobacterium tuberculosis KZN 1435 8162052 YP_003032191.1 CDS TBMG_02226 NC_012943.1 2420358 2421593 R hypothetical protein complement(2420358..2421593) Mycobacterium tuberculosis KZN 1435 8162053 YP_003032192.1 CDS TBMG_02227 NC_012943.1 2421758 2423614 R PE-PGRS family protein complement(2421758..2423614) Mycobacterium tuberculosis KZN 1435 8161730 YP_003032193.1 CDS TBMG_02228 NC_012943.1 2423795 2424154 R hypothetical protein complement(2423795..2424154) Mycobacterium tuberculosis KZN 1435 8164000 YP_003032194.1 CDS TBMG_02229 NC_012943.1 2424222 2424497 R hypothetical protein complement(2424222..2424497) Mycobacterium tuberculosis KZN 1435 8164001 YP_003032195.1 CDS TBMG_02230 NC_012943.1 2424871 2425086 D transposase 2424871..2425086 Mycobacterium tuberculosis KZN 1435 8164002 YP_003032196.1 CDS TBMG_02231 NC_012943.1 2425713 2426969 D hypothetical protein 2425713..2426969 Mycobacterium tuberculosis KZN 1435 8164003 YP_003032197.1 CDS TBMG_02232 NC_012943.1 2427380 2427847 D hypothetical protein 2427380..2427847 Mycobacterium tuberculosis KZN 1435 8164004 YP_003032198.1 CDS TBMG_02233 NC_012943.1 2427987 2428775 D hypothetical protein 2427987..2428775 Mycobacterium tuberculosis KZN 1435 8164005 YP_003032199.1 CDS TBMG_02234 NC_012943.1 2428775 2429158 D hypothetical protein 2428775..2429158 Mycobacterium tuberculosis KZN 1435 8164006 YP_003032200.1 CDS TBMG_02235 NC_012943.1 2429168 2430676 R hypothetical protein complement(2429168..2430676) Mycobacterium tuberculosis KZN 1435 8164007 YP_003032201.1 CDS TBMG_04055 NC_012943.1 2431144 2433996 D PE-PGRS family protein 2431144..2433996 Mycobacterium tuberculosis KZN 1435 8164008 YP_003032202.1 CDS TBMG_02238 NC_012943.1 2434263 2434802 R cutinase cut1 complement(2434263..2434802) Mycobacterium tuberculosis KZN 1435 8164009 YP_003032203.1 CDS TBMG_02239 NC_012943.1 2434801 2435127 D transposase 2434801..2435127 Mycobacterium tuberculosis KZN 1435 8164011 YP_003032204.1 CDS TBMG_02240 NC_012943.1 2435178 2436062 D transposase 2435178..2436062 Mycobacterium tuberculosis KZN 1435 8164010 YP_003032205.1 CDS TBMG_02241 NC_012943.1 2436240 2437751 D hypothetical protein 2436240..2437751 Mycobacterium tuberculosis KZN 1435 8164012 YP_003032206.1 CDS TBMG_02242 NC_012943.1 2437955 2441032 D PPE family protein 2437955..2441032 Mycobacterium tuberculosis KZN 1435 8164013 YP_003032207.1 CDS TBMG_02243 NC_012943.1 2441067 2441516 R hypothetical protein complement(2441067..2441516) Mycobacterium tuberculosis KZN 1435 8164014 YP_003032208.1 CDS TBMG_02244 NC_012943.1 2441643 2443025 R hypothetical protein complement(2441643..2443025) Mycobacterium tuberculosis KZN 1435 8164015 YP_003032209.1 CDS TBMG_02245 NC_012943.1 2443079 2444677 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2443079..2444677 Mycobacterium tuberculosis KZN 1435 8164016 YP_003032210.1 CDS TBMG_02246 NC_012943.1 2444761 2445318 D hypothetical protein 2444761..2445318 Mycobacterium tuberculosis KZN 1435 8164017 YP_003032211.1 CDS TBMG_02247 NC_012943.1 2445315 2446046 R hypothetical protein complement(2445315..2446046) Mycobacterium tuberculosis KZN 1435 8164018 YP_003032212.1 CDS TBMG_02248 NC_012943.1 2446419 2449016 R transmembrane ATP-binding protein ABC transporter complement(2446419..2449016) Mycobacterium tuberculosis KZN 1435 8164019 YP_003032213.1 CDS TBMG_02249 NC_012943.1 2449078 2450508 R anchored-membrane serine/threonine-protein kinase pknF complement(2449078..2450508) Mycobacterium tuberculosis KZN 1435 8164020 YP_003032214.1 CDS TBMG_02250 NC_012943.1 2450655 2451266 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 2450655..2451266 Mycobacterium tuberculosis KZN 1435 8164021 YP_003032215.1 CDS TBMG_02251 NC_012943.1 2451256 2451657 D hypothetical protein 2451256..2451657 Mycobacterium tuberculosis KZN 1435 8164022 YP_003032216.1 CDS TBMG_02252 NC_012943.1 2451942 2453642 R Ser/Thr protein kinase complement(2451942..2453642) Mycobacterium tuberculosis KZN 1435 8164023 YP_003032217.1 CDS TBMG_02253 NC_012943.1 2453736 2454473 R hypothetical protein complement(2453736..2454473) Mycobacterium tuberculosis KZN 1435 8164024 YP_003032218.1 CDS TBMG_02254 NC_012943.1 2454481 2454729 R toxin complement(2454481..2454729) Mycobacterium tuberculosis KZN 1435 8164025 YP_003032219.1 CDS TBMG_02255 NC_012943.1 2454729 2454941 R antitoxin complement(2454729..2454941) Mycobacterium tuberculosis KZN 1435 8164026 YP_003032220.1 CDS TBMG_02256 NC_012943.1 2455009 2456691 D hypothetical protein 2455009..2456691 Mycobacterium tuberculosis KZN 1435 8164027 YP_003032221.1 CDS TBMG_02257 NC_012943.1 2456705 2457166 R hypothetical protein complement(2456705..2457166) Mycobacterium tuberculosis KZN 1435 8164028 YP_003032222.1 CDS TBMG_02258 NC_012943.1 2457276 2458463 D nitrate/nitrite transporter narK2 2457276..2458463 Mycobacterium tuberculosis KZN 1435 8164029 YP_003032223.1 CDS TBMG_02259 NC_012943.1 2458460 2460418 D nitrate reductase narX 2458460..2460418 Mycobacterium tuberculosis KZN 1435 8164030 YP_003032224.1 CDS TBMG_02260 NC_012943.1 2460517 2460759 D hypothetical protein 2460517..2460759 Mycobacterium tuberculosis KZN 1435 8164031 YP_003032225.1 CDS TBMG_02261 NC_012943.1 2460762 2461355 D hypothetical protein 2460762..2461355 Mycobacterium tuberculosis KZN 1435 8164032 YP_003032226.1 CDS TBMG_02262 NC_012943.1 2461630 2461872 D hypothetical protein 2461630..2461872 Mycobacterium tuberculosis KZN 1435 8164033 YP_003032227.1 CDS TBMG_02263 NC_012943.1 2462159 2462791 D hypothetical protein 2462159..2462791 Mycobacterium tuberculosis KZN 1435 8164034 YP_003032228.1 CDS TBMG_02264 NC_012943.1 2462855 2463403 D hypothetical protein 2462855..2463403 Mycobacterium tuberculosis KZN 1435 8164035 YP_003032229.1 CDS gabD2 NC_012943.1 2463413 2464969 R NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase complement(2463413..2464969) Mycobacterium tuberculosis KZN 1435 8164036 YP_003032230.1 CDS TBMG_02266 NC_012943.1 2465335 2466954 D penicillin-binding protein 2465335..2466954 Mycobacterium tuberculosis KZN 1435 8164037 YP_003032231.1 CDS TBMG_04056 NC_012943.1 2466976 2467167 D cell wall surface anchor family protein 2466976..2467167 Mycobacterium tuberculosis KZN 1435 8164038 YP_003032232.1 CDS TBMG_04057 NC_012943.1 2467134 2468072 D hypothetical protein 2467134..2468072 Mycobacterium tuberculosis KZN 1435 8164039 YP_003032233.1 CDS TBMG_02268 NC_012943.1 2468069 2468839 D hypothetical protein 2468069..2468839 Mycobacterium tuberculosis KZN 1435 8164040 YP_003032234.1 CDS TBMG_02269 NC_012943.1 2468864 2469433 R hypothetical protein complement(2468864..2469433) Mycobacterium tuberculosis KZN 1435 8164041 YP_003032235.1 CDS TBMG_02270 NC_012943.1 2469466 2470851 R oxidoreductase complement(2469466..2470851) Mycobacterium tuberculosis KZN 1435 8164042 YP_003032236.1 CDS TBMG_02271 NC_012943.1 2470952 2471662 D hypothetical protein 2470952..2471662 Mycobacterium tuberculosis KZN 1435 8164043 YP_003032237.1 CDS TBMG_02272 NC_012943.1 2471652 2472071 D hypothetical protein 2471652..2472071 Mycobacterium tuberculosis KZN 1435 8164044 YP_003032238.1 CDS TBMG_02273 NC_012943.1 2472114 2473361 R hydrolase complement(2472114..2473361) Mycobacterium tuberculosis KZN 1435 8164045 YP_003032239.1 CDS TBMG_02274 NC_012943.1 2473358 2474842 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase-like protein complement(2473358..2474842) Mycobacterium tuberculosis KZN 1435 8164046 YP_003032240.1 CDS TBMG_04058 NC_012943.1 2475060 2475287 D antitoxin 2475060..2475287 Mycobacterium tuberculosis KZN 1435 8164047 YP_003032241.1 CDS TBMG_02275 NC_012943.1 2475284 2475673 D toxin 2475284..2475673 Mycobacterium tuberculosis KZN 1435 8164048 YP_003032242.1 CDS TBMG_04059 NC_012943.1 2476179 2476286 R hypothetical protein complement(2476179..2476286) Mycobacterium tuberculosis KZN 1435 8164050 YP_003032243.1 CDS TBMG_02276 NC_012943.1 2476283 2477062 R transcriptional regulator complement(2476283..2477062) Mycobacterium tuberculosis KZN 1435 8164051 YP_003032244.1 CDS TBMG_02277 NC_012943.1 2477076 2477894 R hypothetical protein complement(2477076..2477894) Mycobacterium tuberculosis KZN 1435 8164052 YP_003032245.1 CDS TBMG_02278 NC_012943.1 2477979 2478296 R hypothetical protein complement(2477979..2478296) Mycobacterium tuberculosis KZN 1435 8164053 YP_003032246.1 CDS TBMG_02279 NC_012943.1 2478296 2479126 R hypothetical protein complement(2478296..2479126) Mycobacterium tuberculosis KZN 1435 8164054 YP_003032247.1 CDS TBMG_02280 NC_012943.1 2479129 2480043 R 3-hydroxybutyryl-CoA dehydrogenase complement(2479129..2480043) Mycobacterium tuberculosis KZN 1435 8164055 YP_003032248.1 CDS TBMG_02281 NC_012943.1 2480037 2480849 R oxidoreductase complement(2480037..2480849) Mycobacterium tuberculosis KZN 1435 8164056 YP_003032249.1 CDS engA NC_012943.1 2481023 2482414 R synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2481023..2482414) Mycobacterium tuberculosis KZN 1435 8164057 YP_003032250.1 CDS cmk NC_012943.1 2482411 2483103 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(2482411..2483103) Mycobacterium tuberculosis KZN 1435 8164058 YP_003032251.1 CDS TBMG_02284 NC_012943.1 2483100 2483864 R hypothetical protein complement(2483100..2483864) Mycobacterium tuberculosis KZN 1435 8164059 YP_003032252.1 CDS TBMG_02285 NC_012943.1 2483861 2484556 R hypothetical protein complement(2483861..2484556) Mycobacterium tuberculosis KZN 1435 8164060 YP_003032253.1 CDS TBMG_02286 NC_012943.1 2484553 2485389 R ScpA/B family protein complement(2484553..2485389) Mycobacterium tuberculosis KZN 1435 8164061 YP_003032254.1 CDS TBMG_02287 NC_012943.1 2485386 2486342 R initiation inhibitor protein complement(2485386..2486342) Mycobacterium tuberculosis KZN 1435 8164062 YP_003032255.1 CDS TBMG_02288 NC_012943.1 2486360 2487820 R hypothetical protein complement(2486360..2487820) Mycobacterium tuberculosis KZN 1435 8164063 YP_003032256.1 CDS TBMG_02289 NC_012943.1 2488053 2488220 D hypothetical protein 2488053..2488220 Mycobacterium tuberculosis KZN 1435 8164064 YP_003032257.1 CDS TBMG_02290 NC_012943.1 2488824 2490008 D PPE family protein 2488824..2490008 Mycobacterium tuberculosis KZN 1435 8164065 YP_003032258.1 CDS TBMG_02291 NC_012943.1 2490048 2491205 D PPE family protein 2490048..2491205 Mycobacterium tuberculosis KZN 1435 8164066 YP_003032259.1 CDS TBMG_02292 NC_012943.1 2491246 2492916 D D-serine/alanine/glycine transporter cycA 2491246..2492916 Mycobacterium tuberculosis KZN 1435 8164067 YP_003032260.1 CDS TBMG_02293 NC_012943.1 2492870 2493571 D catechol-O-methyltransferase 2492870..2493571 Mycobacterium tuberculosis KZN 1435 8164068 YP_003032261.1 CDS TBMG_02294 NC_012943.1 2494127 2495491 D hypothetical protein 2494127..2495491 Mycobacterium tuberculosis KZN 1435 8164069 YP_003032262.1 CDS xerD NC_012943.1 2495565 2496500 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(2495565..2496500) Mycobacterium tuberculosis KZN 1435 8164070 YP_003032263.1 CDS TBMG_02296 NC_012943.1 2496497 2497120 R hypothetical protein complement(2496497..2497120) Mycobacterium tuberculosis KZN 1435 8164071 YP_003032264.1 CDS pyrG NC_012943.1 2497113 2498873 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(2497113..2498873) Mycobacterium tuberculosis KZN 1435 8164072 YP_003032265.1 CDS TBMG_02298 NC_012943.1 2499013 2499957 R hypothetical protein complement(2499013..2499957) Mycobacterium tuberculosis KZN 1435 8164073 YP_003032266.1 CDS TBMG_02299 NC_012943.1 2499979 2501160 R hypothetical protein complement(2499979..2501160) Mycobacterium tuberculosis KZN 1435 8164074 YP_003032267.1 CDS TBMG_02300 NC_012943.1 2501256 2503019 R DNA repair protein recN complement(2501256..2503019) Mycobacterium tuberculosis KZN 1435 8164075 YP_003032268.1 CDS ppnK NC_012943.1 2503033 2503956 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(2503033..2503956) Mycobacterium tuberculosis KZN 1435 8164076 YP_003032269.1 CDS TBMG_02302 NC_012943.1 2503956 2504762 R cytotoxin/hemolysin tlyA complement(2503956..2504762) Mycobacterium tuberculosis KZN 1435 8164077 YP_003032270.1 CDS TBMG_02303 NC_012943.1 2504943 2506004 R phosphatase complement(2504943..2506004) Mycobacterium tuberculosis KZN 1435 8164078 YP_003032271.1 CDS TBMG_02304 NC_012943.1 2506001 2506753 R hypothetical protein complement(2506001..2506753) Mycobacterium tuberculosis KZN 1435 8164079 YP_003032272.1 CDS TBMG_02305 NC_012943.1 2506792 2507175 R hypothetical protein complement(2506792..2507175) Mycobacterium tuberculosis KZN 1435 8163623 YP_003032273.1 CDS TBMG_02306 NC_012943.1 2507826 2509100 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(2507826..2509100) Mycobacterium tuberculosis KZN 1435 8163624 YP_003032274.1 CDS TBMG_02307 NC_012943.1 2509112 2509723 R responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase complement(2509112..2509723) Mycobacterium tuberculosis KZN 1435 8160578 YP_003032275.1 CDS TBMG_02308 NC_012943.1 2509782 2510549 D ABC transporter ATP-binding protein 2509782..2510549 Mycobacterium tuberculosis KZN 1435 8160579 YP_003032276.1 CDS TBMG_02309 NC_012943.1 2510621 2511301 D hypothetical protein 2510621..2511301 Mycobacterium tuberculosis KZN 1435 8160580 YP_003032277.1 CDS TBMG_02310 NC_012943.1 2511303 2511926 D hypothetical protein 2511303..2511926 Mycobacterium tuberculosis KZN 1435 8160581 YP_003032278.1 CDS TBMG_04060 NC_012943.1 2511892 2512116 R hypothetical protein complement(2511892..2512116) Mycobacterium tuberculosis KZN 1435 8160582 YP_003032279.1 CDS TBMG_02311 NC_012943.1 2512109 2515108 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(2512109..2515108) Mycobacterium tuberculosis KZN 1435 8160583 YP_003032280.1 CDS TBMG_02312 NC_012943.1 2515382 2516299 R hypothetical protein complement(2515382..2516299) Mycobacterium tuberculosis KZN 1435 8160584 YP_003032281.1 CDS TBMG_02313 NC_012943.1 2516460 2517455 R molybdopterin biosynthesis protein moeX complement(2516460..2517455) Mycobacterium tuberculosis KZN 1435 8160585 YP_003032282.1 CDS TBMG_02314 NC_012943.1 2517449 2518273 R hypothetical protein complement(2517449..2518273) Mycobacterium tuberculosis KZN 1435 8160586 YP_003032283.1 CDS TBMG_02315 NC_012943.1 2518282 2519403 R acyl-CoA dehydrogenase complement(2518282..2519403) Mycobacterium tuberculosis KZN 1435 8160587 YP_003032284.1 CDS TBMG_02316 NC_012943.1 2519403 2520311 R hypothetical protein complement(2519403..2520311) Mycobacterium tuberculosis KZN 1435 8160588 YP_003032285.1 CDS TBMG_02317 NC_012943.1 2520406 2520954 R lipoprotein dsbF complement(2520406..2520954) Mycobacterium tuberculosis KZN 1435 8160589 YP_003032286.1 CDS TBMG_02318 NC_012943.1 2520951 2521655 R hypothetical protein complement(2520951..2521655) Mycobacterium tuberculosis KZN 1435 8160590 YP_003032287.1 CDS TBMG_02319 NC_012943.1 2521727 2522461 D transcriptional regulator 2521727..2522461 Mycobacterium tuberculosis KZN 1435 8160591 YP_003032288.1 CDS TBMG_02320 NC_012943.1 2522786 2523442 D transcriptional regulator 2522786..2523442 Mycobacterium tuberculosis KZN 1435 8160592 YP_003032289.1 CDS TBMG_02321 NC_012943.1 2523470 2524402 D hypothetical protein 2523470..2524402 Mycobacterium tuberculosis KZN 1435 8160593 YP_003032290.1 CDS TBMG_02322 NC_012943.1 2524495 2525826 D membrane transporter 2524495..2525826 Mycobacterium tuberculosis KZN 1435 8160594 YP_003032291.1 CDS TBMG_02323 NC_012943.1 2525835 2526230 R hypothetical protein complement(2525835..2526230) Mycobacterium tuberculosis KZN 1435 8160595 YP_003032292.1 CDS TBMG_02324 NC_012943.1 2526235 2526582 R hypothetical protein complement(2526235..2526582) Mycobacterium tuberculosis KZN 1435 8160596 YP_003032293.1 CDS TBMG_02325 NC_012943.1 2526615 2526977 R hypothetical protein complement(2526615..2526977) Mycobacterium tuberculosis KZN 1435 8160597 YP_003032294.1 CDS TBMG_02326 NC_012943.1 2527360 2529135 D macrolide-transport ATP-binding protein ABC transporter 2527360..2529135 Mycobacterium tuberculosis KZN 1435 8160598 YP_003032295.1 CDS TBMG_02327 NC_012943.1 2529150 2530442 D cytochrome P450 139 cyp139 2529150..2530442 Mycobacterium tuberculosis KZN 1435 8160599 YP_003032296.1 CDS TBMG_02328 NC_012943.1 2530425 2531486 R chalcone synthase pks11 complement(2530425..2531486) Mycobacterium tuberculosis KZN 1435 8160600 YP_003032297.1 CDS TBMG_02329 NC_012943.1 2531633 2534686 R polyketide synthase complement(2531633..2534686) Mycobacterium tuberculosis KZN 1435 8160601 YP_003032298.1 CDS TBMG_02330 NC_012943.1 2534692 2536224 R polyketide synthase complement(2534692..2536224) Mycobacterium tuberculosis KZN 1435 8160602 YP_003032299.1 CDS TBMG_02331 NC_012943.1 2536200 2541008 R polyketide synthase complement(2536200..2541008) Mycobacterium tuberculosis KZN 1435 8160603 YP_003032300.1 CDS TBMG_02332 NC_012943.1 2541028 2547408 R polyketide synthase complement(2541028..2547408) Mycobacterium tuberculosis KZN 1435 8160604 YP_003032301.1 CDS TBMG_02333 NC_012943.1 2547491 2548552 R chalcone synthase pks10 complement(2547491..2548552) Mycobacterium tuberculosis KZN 1435 8160605 YP_003032302.1 CDS TBMG_02334 NC_012943.1 2548661 2550073 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(2548661..2550073) Mycobacterium tuberculosis KZN 1435 8160606 YP_003032303.1 CDS TBMG_02335 NC_012943.1 2550153 2551349 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(2550153..2551349) Mycobacterium tuberculosis KZN 1435 8160607 YP_003032304.1 CDS TBMG_02336 NC_012943.1 2551358 2551888 R regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR complement(2551358..2551888) Mycobacterium tuberculosis KZN 1435 8160608 YP_003032305.1 CDS TBMG_02337 NC_012943.1 2551867 2552790 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase complement(2551867..2552790) Mycobacterium tuberculosis KZN 1435 8160609 YP_003032306.1 CDS argD NC_012943.1 2552787 2553989 R catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase complement(2552787..2553989) Mycobacterium tuberculosis KZN 1435 8160610 YP_003032307.1 CDS TBMG_02339 NC_012943.1 2553986 2554870 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(2553986..2554870) Mycobacterium tuberculosis KZN 1435 8160611 YP_003032308.1 CDS argJ NC_012943.1 2554867 2556081 R bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein complement(2554867..2556081) Mycobacterium tuberculosis KZN 1435 8160612 YP_003032309.1 CDS argC NC_012943.1 2556078 2557136 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(2556078..2557136) Mycobacterium tuberculosis KZN 1435 8160613 YP_003032310.1 CDS TBMG_02342 NC_012943.1 2557330 2560365 D PE-PGRS family protein 2557330..2560365 Mycobacterium tuberculosis KZN 1435 8160614 YP_003032311.1 CDS pheT NC_012943.1 2560459 2562954 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2560459..2562954) Mycobacterium tuberculosis KZN 1435 8160615 YP_003032312.1 CDS pheS NC_012943.1 2562954 2564012 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(2562954..2564012) Mycobacterium tuberculosis KZN 1435 8160616 YP_003032313.1 CDS TBMG_02345 NC_012943.1 2564175 2564981 R hypothetical protein complement(2564175..2564981) Mycobacterium tuberculosis KZN 1435 8160617 YP_003032314.1 CDS TBMG_02346 NC_012943.1 2564988 2565938 R hypothetical protein complement(2564988..2565938) Mycobacterium tuberculosis KZN 1435 8160618 YP_003032315.1 CDS TBMG_02347 NC_012943.1 2566016 2566948 R PE family protein complement(2566016..2566948) Mycobacterium tuberculosis KZN 1435 8160619 YP_003032316.1 CDS TBMG_02348 NC_012943.1 2567258 2568313 D hypothetical protein 2567258..2568313 Mycobacterium tuberculosis KZN 1435 8160620 YP_003032317.1 CDS TBMG_02349 NC_012943.1 2568324 2569106 R 23S rRNA methyltransferase complement(2568324..2569106) Mycobacterium tuberculosis KZN 1435 8160621 YP_003032318.1 CDS rplT NC_012943.1 2569139 2569528 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(2569139..2569528) Mycobacterium tuberculosis KZN 1435 8160622 YP_003032319.1 CDS rpmI NC_012943.1 2569590 2569784 R 50S ribosomal protein L35 complement(2569590..2569784) Mycobacterium tuberculosis KZN 1435 8160623 YP_003032320.1 CDS infC NC_012943.1 2569834 2570388 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(2569834..2570388) Mycobacterium tuberculosis KZN 1435 8160624 YP_003032321.1 CDS lysS NC_012943.1 2570671 2574195 D catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 2570671..2574195 Mycobacterium tuberculosis KZN 1435 8160625 YP_003032322.1 CDS TBMG_04061 NC_012943.1 2574254 2574529 D hypothetical protein 2574254..2574529 Mycobacterium tuberculosis KZN 1435 8160626 YP_003032323.1 CDS TBMG_02354 NC_012943.1 2574542 2575723 D hypothetical protein 2574542..2575723 Mycobacterium tuberculosis KZN 1435 8160627 YP_003032324.1 CDS TBMG_02355 NC_012943.1 2575739 2575996 D hypothetical protein 2575739..2575996 Mycobacterium tuberculosis KZN 1435 8160628 YP_003032325.1 CDS uvrA NC_012943.1 2576053 2578971 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(2576053..2578971) Mycobacterium tuberculosis KZN 1435 8160629 YP_003032326.1 CDS TBMG_02357 NC_012943.1 2579020 2579814 D hypothetical protein 2579020..2579814 Mycobacterium tuberculosis KZN 1435 8160630 YP_003032327.1 CDS TBMG_02358 NC_012943.1 2579821 2580261 R hypothetical protein complement(2579821..2580261) Mycobacterium tuberculosis KZN 1435 8160631 YP_003032328.1 CDS TBMG_02359 NC_012943.1 2580443 2582140 D hypothetical protein 2580443..2582140 Mycobacterium tuberculosis KZN 1435 8160632 YP_003032329.1 CDS TBMG_02360 NC_012943.1 2582129 2583544 R hypothetical protein complement(2582129..2583544) Mycobacterium tuberculosis KZN 1435 8160633 YP_003032330.1 CDS TBMG_02361 NC_012943.1 2583541 2585760 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(2583541..2585760) Mycobacterium tuberculosis KZN 1435 8160634 YP_003032331.1 CDS TBMG_02362 NC_012943.1 2585882 2586325 D hypothetical protein 2585882..2586325 Mycobacterium tuberculosis KZN 1435 8160635 YP_003032332.1 CDS coaE NC_012943.1 2586476 2587699 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain; dephospho-CoA kinase/protein folding accessory domain-containing protein complement(2586476..2587699) Mycobacterium tuberculosis KZN 1435 8160636 YP_003032333.1 CDS rpsA NC_012943.1 2587725 2589170 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(2587725..2589170) Mycobacterium tuberculosis KZN 1435 8160637 YP_003032334.1 CDS TBMG_02365 NC_012943.1 2589333 2592047 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(2589333..2592047) Mycobacterium tuberculosis KZN 1435 8160638 YP_003032335.1 CDS TBMG_02366 NC_012943.1 2592151 2592642 D hypothetical protein 2592151..2592642 Mycobacterium tuberculosis KZN 1435 8160639 YP_003032336.1 CDS TBMG_02367 NC_012943.1 2592639 2593847 D lipid-transfer protein 2592639..2593847 Mycobacterium tuberculosis KZN 1435 8160640 YP_003032337.1 CDS TBMG_02368 NC_012943.1 2593915 2594541 R two component system transcriptional regulator complement(2593915..2594541) Mycobacterium tuberculosis KZN 1435 8160641 YP_003032338.1 CDS TBMG_02369 NC_012943.1 2594767 2596098 D membrane-anchored adenylyl cyclase cya 2594767..2596098 Mycobacterium tuberculosis KZN 1435 8160643 YP_003032339.1 CDS TBMG_02370 NC_012943.1 2596127 2596714 D hypothetical protein 2596127..2596714 Mycobacterium tuberculosis KZN 1435 8160644 YP_003032340.1 CDS TBMG_02371 NC_012943.1 2596825 2598282 D membrane cytochrome D ubiquinol oxidase subunit I cydA 2596825..2598282 Mycobacterium tuberculosis KZN 1435 8160645 YP_003032341.1 CDS TBMG_02372 NC_012943.1 2598312 2599352 D membrane cytochrome D ubiquinol oxidase subunit II cydB 2598312..2599352 Mycobacterium tuberculosis KZN 1435 8160646 YP_003032342.1 CDS TBMG_02373 NC_012943.1 2599439 2601022 D transmembrane ATP-binding protein ABC transporter cydD 2599439..2601022 Mycobacterium tuberculosis KZN 1435 8160647 YP_003032343.1 CDS TBMG_02374 NC_012943.1 2601019 2602749 D transmembrane ATP-binding protein ABC transporter cydC 2601019..2602749 Mycobacterium tuberculosis KZN 1435 8160648 YP_003032344.1 CDS TBMG_02375 NC_012943.1 2602683 2604137 R hypothetical protein complement(2602683..2604137) Mycobacterium tuberculosis KZN 1435 8160649 YP_003032345.1 CDS TBMG_02376 NC_012943.1 2604195 2605097 R acyl-CoA thioesterase complement(2604195..2605097) Mycobacterium tuberculosis KZN 1435 8160650 YP_003032346.1 CDS TBMG_02377 NC_012943.1 2605105 2606523 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(2605105..2606523) Mycobacterium tuberculosis KZN 1435 8160651 YP_003032347.1 CDS TBMG_02378 NC_012943.1 2606631 2607029 R hypothetical protein complement(2606631..2607029) Mycobacterium tuberculosis KZN 1435 8160652 YP_003032348.1 CDS TBMG_02379 NC_012943.1 2607019 2607459 R hypothetical protein complement(2607019..2607459) Mycobacterium tuberculosis KZN 1435 8160653 YP_003032349.1 CDS TBMG_02380 NC_012943.1 2608135 2609544 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(2608135..2609544) Mycobacterium tuberculosis KZN 1435 8160654 YP_003032350.1 CDS trpA NC_012943.1 2609541 2610353 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(2609541..2610353) Mycobacterium tuberculosis KZN 1435 8160655 YP_003032351.1 CDS TBMG_02382 NC_012943.1 2610353 2611621 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(2610353..2611621) Mycobacterium tuberculosis KZN 1435 8160656 YP_003032352.1 CDS trpC NC_012943.1 2611654 2612502 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase complement(2611654..2612502) Mycobacterium tuberculosis KZN 1435 8160657 YP_003032353.1 CDS TBMG_02384 NC_012943.1 2612562 2613269 R hypothetical protein complement(2612562..2613269) Mycobacterium tuberculosis KZN 1435 8160658 YP_003032354.1 CDS TBMG_02385 NC_012943.1 2613259 2614809 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(2613259..2614809) Mycobacterium tuberculosis KZN 1435 8160659 YP_003032355.1 CDS TBMG_02386 NC_012943.1 2614950 2615414 D peroxidoxin bcpB 2614950..2615414 Mycobacterium tuberculosis KZN 1435 8160660 YP_003032356.1 CDS TBMG_02387 NC_012943.1 2615449 2616531 R hypothetical protein complement(2615449..2616531) Mycobacterium tuberculosis KZN 1435 8160661 YP_003032357.1 CDS hisI NC_012943.1 2616712 2617059 R PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase complement(2616712..2617059) Mycobacterium tuberculosis KZN 1435 8160662 YP_003032358.1 CDS TBMG_02389 NC_012943.1 2617056 2617859 R catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF complement(2617056..2617859) Mycobacterium tuberculosis KZN 1435 8160663 YP_003032359.1 CDS TBMG_02390 NC_012943.1 2617861 2618673 R inositol-monophosphatase impA complement(2617861..2618673) Mycobacterium tuberculosis KZN 1435 8160664 YP_003032360.1 CDS TBMG_02391 NC_012943.1 2618681 2619418 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A complement(2618681..2619418) Mycobacterium tuberculosis KZN 1435 8160665 YP_003032361.1 CDS hisH NC_012943.1 2619428 2620048 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(2619428..2620048) Mycobacterium tuberculosis KZN 1435 8160666 YP_003032362.1 CDS hisB NC_012943.1 2620045 2620677 R catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase complement(2620045..2620677) Mycobacterium tuberculosis KZN 1435 8160667 YP_003032363.1 CDS TBMG_02394 NC_012943.1 2620674 2621816 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(2620674..2621816) Mycobacterium tuberculosis KZN 1435 8160668 YP_003032364.1 CDS hisD NC_012943.1 2621813 2623156 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(2621813..2623156) Mycobacterium tuberculosis KZN 1435 8160669 YP_003032365.1 CDS TBMG_02396 NC_012943.1 2623229 2623639 D hypothetical protein 2623229..2623639 Mycobacterium tuberculosis KZN 1435 8160670 YP_003032366.1 CDS TBMG_02397 NC_012943.1 2623660 2624418 R hypothetical protein complement(2623660..2624418) Mycobacterium tuberculosis KZN 1435 8160671 YP_003032367.1 CDS TBMG_02398 NC_012943.1 2624467 2625324 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(2624467..2625324) Mycobacterium tuberculosis KZN 1435 8160672 YP_003032368.1 CDS TBMG_02399 NC_012943.1 2625324 2626907 R catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase complement(2625324..2626907) Mycobacterium tuberculosis KZN 1435 8160673 YP_003032369.1 CDS TBMG_02400 NC_012943.1 2626907 2627956 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(2626907..2627956) Mycobacterium tuberculosis KZN 1435 8160674 YP_003032370.1 CDS TBMG_02401 NC_012943.1 2628005 2628715 D hypothetical protein 2628005..2628715 Mycobacterium tuberculosis KZN 1435 8160675 YP_003032371.1 CDS TBMG_02402 NC_012943.1 2628972 2630312 D hypothetical protein 2628972..2630312 Mycobacterium tuberculosis KZN 1435 8160676 YP_003032372.1 CDS TBMG_02403 NC_012943.1 2630477 2631142 R hypothetical protein complement(2630477..2631142) Mycobacterium tuberculosis KZN 1435 8160677 YP_003032373.1 CDS TBMG_02404 NC_012943.1 2631379 2632428 R catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase complement(2631379..2632428) Mycobacterium tuberculosis KZN 1435 8160678 YP_003032374.1 CDS TBMG_02405 NC_012943.1 2632876 2633544 D hypothetical protein 2632876..2633544 Mycobacterium tuberculosis KZN 1435 8160679 YP_003032375.1 CDS TBMG_02406 NC_012943.1 2633309 2634271 D hypothetical protein 2633309..2634271 Mycobacterium tuberculosis KZN 1435 8160680 YP_003032376.1 CDS TBMG_02407 NC_012943.1 2634417 2634926 R hypothetical protein complement(2634417..2634926) Mycobacterium tuberculosis KZN 1435 8160681 YP_003032377.1 CDS bioD NC_012943.1 2634926 2635606 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(2634926..2635606) Mycobacterium tuberculosis KZN 1435 8160682 YP_003032378.1 CDS TBMG_02409 NC_012943.1 2635603 2636763 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(2635603..2636763) Mycobacterium tuberculosis KZN 1435 8160683 YP_003032379.1 CDS TBMG_02410 NC_012943.1 2636760 2638073 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(2636760..2638073) Mycobacterium tuberculosis KZN 1435 8160684 YP_003032380.1 CDS TBMG_02411 NC_012943.1 2638033 2638605 D hypothetical protein 2638033..2638605 Mycobacterium tuberculosis KZN 1435 8160686 YP_003032381.1 CDS TBMG_02412 NC_012943.1 2638788 2639537 D invasion-associated protein 2638788..2639537 Mycobacterium tuberculosis KZN 1435 8160685 YP_003032382.1 CDS TBMG_02413 NC_012943.1 2639636 2641825 D hypothetical protein 2639636..2641825 Mycobacterium tuberculosis KZN 1435 8160687 YP_003032383.1 CDS TBMG_02414 NC_012943.1 2641864 2644029 D maltooligosyltrehalose synthase treX 2641864..2644029 Mycobacterium tuberculosis KZN 1435 8160688 YP_003032384.1 CDS TBMG_02415 NC_012943.1 2644033 2646330 D maltooligosyltrehalose synthase treY 2644033..2646330 Mycobacterium tuberculosis KZN 1435 8160689 YP_003032385.1 CDS TBMG_02416 NC_012943.1 2646323 2648065 D maltooligosyltrehalose trehalohydrolase treZ 2646323..2648065 Mycobacterium tuberculosis KZN 1435 8160690 YP_003032386.1 CDS TBMG_02417 NC_012943.1 2648082 2648486 R toxin complement(2648082..2648486) Mycobacterium tuberculosis KZN 1435 8160691 YP_003032387.1 CDS TBMG_02418 NC_012943.1 2648492 2648710 R antitoxin complement(2648492..2648710) Mycobacterium tuberculosis KZN 1435 8160692 YP_003032388.1 CDS TBMG_02419 NC_012943.1 2648748 2650037 R catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase complement(2648748..2650037) Mycobacterium tuberculosis KZN 1435 8160693 YP_003032389.1 CDS TBMG_02420 NC_012943.1 2650072 2650518 R hypothetical protein complement(2650072..2650518) Mycobacterium tuberculosis KZN 1435 8160694 YP_003032390.1 CDS TBMG_02421 NC_012943.1 2650528 2651721 R transmembrane transporter mmpL6 complement(2650528..2651721) Mycobacterium tuberculosis KZN 1435 8160695 YP_003032391.1 CDS TBMG_02422 NC_012943.1 2651860 2652468 R regulatory protein complement(2651860..2652468) Mycobacterium tuberculosis KZN 1435 8160696 YP_003032392.1 CDS TBMG_02423 NC_012943.1 2652536 2652913 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(2652536..2652913) Mycobacterium tuberculosis KZN 1435 8160697 YP_003032393.1 CDS TBMG_02424 NC_012943.1 2652910 2653290 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(2652910..2653290) Mycobacterium tuberculosis KZN 1435 8160698 YP_003032394.1 CDS TBMG_02425 NC_012943.1 2653287 2654030 R fumarate reductase iron-sulfur subunit frdB complement(2653287..2654030) Mycobacterium tuberculosis KZN 1435 8160699 YP_003032395.1 CDS TBMG_02426 NC_012943.1 2654033 2655784 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(2654033..2655784) Mycobacterium tuberculosis KZN 1435 8160700 YP_003032396.1 CDS TBMG_02427 NC_012943.1 2656155 2658020 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(2656155..2658020) Mycobacterium tuberculosis KZN 1435 8160701 YP_003032397.1 CDS TBMG_02428 NC_012943.1 2658034 2659749 R fatty-acid-CoA ligase fadD11 complement(2658034..2659749) Mycobacterium tuberculosis KZN 1435 8160702 YP_003032398.1 CDS TBMG_02429 NC_012943.1 2660133 2662169 D PPE family protein 2660133..2662169 Mycobacterium tuberculosis KZN 1435 8160703 YP_003032399.1 CDS dnaE NC_012943.1 2662218 2665772 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(2662218..2665772) Mycobacterium tuberculosis KZN 1435 8160704 YP_003032400.1 CDS TBMG_02431 NC_012943.1 2665840 2666271 R hypothetical protein complement(2665840..2666271) Mycobacterium tuberculosis KZN 1435 8160705 YP_003032401.1 CDS TBMG_02432 NC_012943.1 2666320 2666547 R hypothetical protein complement(2666320..2666547) Mycobacterium tuberculosis KZN 1435 8160706 YP_003032402.1 CDS TBMG_02433 NC_012943.1 2666569 2667372 R ketoacyl reductase complement(2666569..2667372) Mycobacterium tuberculosis KZN 1435 8160707 YP_003032403.1 CDS TBMG_02434 NC_012943.1 2667377 2668402 R fatty-acyl-CoA reductase complement(2667377..2668402) Mycobacterium tuberculosis KZN 1435 8160708 YP_003032404.1 CDS TBMG_02435 NC_012943.1 2668630 2669040 D hemoglobin glbN 2668630..2669040 Mycobacterium tuberculosis KZN 1435 8160709 YP_003032405.1 CDS TBMG_02436 NC_012943.1 2669095 2669688 D hypothetical protein 2669095..2669688 Mycobacterium tuberculosis KZN 1435 8160710 YP_003032406.1 CDS TBMG_02437 NC_012943.1 2669695 2670621 R hypothetical protein complement(2669695..2670621) Mycobacterium tuberculosis KZN 1435 8160711 YP_003032407.1 CDS TBMG_02438 NC_012943.1 2670614 2671288 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(2670614..2671288) Mycobacterium tuberculosis KZN 1435 8160712 YP_003032408.1 CDS TBMG_02439 NC_012943.1 2671274 2672254 D L-aparaginase ansA 2671274..2672254 Mycobacterium tuberculosis KZN 1435 8160714 YP_003032409.1 CDS TBMG_02440 NC_012943.1 2672219 2673625 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(2672219..2673625) Mycobacterium tuberculosis KZN 1435 8160713 YP_003032410.1 CDS ileS NC_012943.1 2673822 2676947 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase complement(2673822..2676947) Mycobacterium tuberculosis KZN 1435 8160715 YP_003032411.1 CDS TBMG_02442 NC_012943.1 2677254 2677490 R hypothetical protein complement(2677254..2677490) Mycobacterium tuberculosis KZN 1435 8160716 YP_003032412.1 CDS TBMG_02443 NC_012943.1 2678055 2678732 R transcriptional regulator complement(2678055..2678732) Mycobacterium tuberculosis KZN 1435 8160717 YP_003032413.1 CDS TBMG_02444 NC_012943.1 2678729 2679856 R hypothetical protein complement(2678729..2679856) Mycobacterium tuberculosis KZN 1435 8160718 YP_003032414.1 CDS TBMG_02445 NC_012943.1 2679916 2680350 D hypothetical protein 2679916..2680350 Mycobacterium tuberculosis KZN 1435 8160719 YP_003032415.1 CDS TBMG_02446 NC_012943.1 2680427 2680993 R hypothetical protein complement(2680427..2680993) Mycobacterium tuberculosis KZN 1435 8160720 YP_003032416.1 CDS TBMG_02447 NC_012943.1 2680990 2682093 R alcohol dehydrogenase complement(2680990..2682093) Mycobacterium tuberculosis KZN 1435 8160721 YP_003032417.1 CDS TBMG_02448 NC_012943.1 2682210 2683964 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(2682210..2683964) Mycobacterium tuberculosis KZN 1435 8160722 YP_003032418.1 CDS TBMG_02449 NC_012943.1 2684016 2684513 D polyketide synthase 2684016..2684513 Mycobacterium tuberculosis KZN 1435 8160723 YP_003032419.1 CDS TBMG_02450 NC_012943.1 2685057 2691383 D polyketide synthase 2685057..2691383 Mycobacterium tuberculosis KZN 1435 8160724 YP_003032420.1 CDS TBMG_02451 NC_012943.1 2691406 2692686 D glycosyltransferase 2691406..2692686 Mycobacterium tuberculosis KZN 1435 8160725 YP_003032421.1 CDS TBMG_02452 NC_012943.1 2692664 2693449 R rhamnosyl transferase wbbL2 complement(2692664..2693449) Mycobacterium tuberculosis KZN 1435 8160726 YP_003032422.1 CDS TBMG_02453 NC_012943.1 2693496 2694740 R glycosyltransferase complement(2693496..2694740) Mycobacterium tuberculosis KZN 1435 8160727 YP_003032423.1 CDS TBMG_02454 NC_012943.1 2694770 2695813 R methyltransferase complement(2694770..2695813) Mycobacterium tuberculosis KZN 1435 8160728 YP_003032424.1 CDS TBMG_02455 NC_012943.1 2695758 2699294 D transmembrane transporter mmpL12 2695758..2699294 Mycobacterium tuberculosis KZN 1435 8160730 YP_003032425.1 CDS TBMG_02456 NC_012943.1 2699413 2701164 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(2699413..2701164) Mycobacterium tuberculosis KZN 1435 8160729 YP_003032426.1 CDS TBMG_02457 NC_012943.1 2701398 2702471 R sugar transferase complement(2701398..2702471) Mycobacterium tuberculosis KZN 1435 8160731 YP_003032427.1 CDS TBMG_02458 NC_012943.1 2702863 2703822 R hypothetical protein complement(2702863..2703822) Mycobacterium tuberculosis KZN 1435 8160732 YP_003032428.1 CDS TBMG_02459 NC_012943.1 2703831 2704595 R hypothetical protein complement(2703831..2704595) Mycobacterium tuberculosis KZN 1435 8160733 YP_003032429.1 CDS TBMG_02460 NC_012943.1 2704927 2705937 D sugar transferase 2704927..2705937 Mycobacterium tuberculosis KZN 1435 8160734 YP_003032430.1 CDS TBMG_02461 NC_012943.1 2705940 2706836 D hypothetical protein 2705940..2706836 Mycobacterium tuberculosis KZN 1435 8160735 YP_003032431.1 CDS TBMG_02462 NC_012943.1 2706871 2707659 D hypothetical protein 2706871..2707659 Mycobacterium tuberculosis KZN 1435 8160736 YP_003032432.1 CDS TBMG_02463 NC_012943.1 2707677 2708408 R hypothetical protein complement(2707677..2708408) Mycobacterium tuberculosis KZN 1435 8160737 YP_003032433.1 CDS TBMG_02464 NC_012943.1 2708405 2709373 R nucleotide-sugar epimerase epiA complement(2708405..2709373) Mycobacterium tuberculosis KZN 1435 8160738 YP_003032434.1 CDS TBMG_02465 NC_012943.1 2709370 2710416 R GDP-D-mannose dehydratase gmdA complement(2709370..2710416) Mycobacterium tuberculosis KZN 1435 8160739 YP_003032435.1 CDS TBMG_02466 NC_012943.1 2710450 2710869 R hypothetical protein complement(2710450..2710869) Mycobacterium tuberculosis KZN 1435 8160740 YP_003032436.1 CDS TBMG_02467 NC_012943.1 2710873 2712171 R hypothetical protein complement(2710873..2712171) Mycobacterium tuberculosis KZN 1435 8164493 YP_003032437.1 CDS TBMG_02468 NC_012943.1 2712373 2713254 R hypothetical protein complement(2712373..2713254) Mycobacterium tuberculosis KZN 1435 8160825 YP_003032438.1 CDS TBMG_02469 NC_012943.1 2713238 2713600 R hypothetical protein complement(2713238..2713600) Mycobacterium tuberculosis KZN 1435 8160826 YP_003032439.1 CDS TBMG_02470 NC_012943.1 2713572 2715371 D hypothetical protein 2713572..2715371 Mycobacterium tuberculosis KZN 1435 8160828 YP_003032440.1 CDS TBMG_02471 NC_012943.1 2715607 2716110 R hypothetical protein complement(2715607..2716110) Mycobacterium tuberculosis KZN 1435 8160827 YP_003032441.1 CDS TBMG_02472 NC_012943.1 2716044 2716739 D hypothetical protein 2716044..2716739 Mycobacterium tuberculosis KZN 1435 8160830 YP_003032442.1 CDS TBMG_02473 NC_012943.1 2717023 2717523 D hypothetical protein 2717023..2717523 Mycobacterium tuberculosis KZN 1435 8160829 YP_003032443.1 CDS TBMG_02474 NC_012943.1 2717520 2718185 D hypothetical protein 2717520..2718185 Mycobacterium tuberculosis KZN 1435 8160831 YP_003032444.1 CDS TBMG_02475 NC_012943.1 2718322 2718921 D hypothetical protein 2718322..2718921 Mycobacterium tuberculosis KZN 1435 8160832 YP_003032445.1 CDS TBMG_02476 NC_012943.1 2718928 2719470 D hypothetical protein 2718928..2719470 Mycobacterium tuberculosis KZN 1435 8160833 YP_003032446.1 CDS TBMG_02477 NC_012943.1 2719643 2720542 R hypothetical protein complement(2719643..2720542) Mycobacterium tuberculosis KZN 1435 8160834 YP_003032447.1 CDS TBMG_02478 NC_012943.1 2720755 2721576 R hypothetical protein complement(2720755..2721576) Mycobacterium tuberculosis KZN 1435 8160835 YP_003032448.1 CDS TBMG_02479 NC_012943.1 2721588 2722616 R glycosyltransferase complement(2721588..2722616) Mycobacterium tuberculosis KZN 1435 8160836 YP_003032449.1 CDS TBMG_02480 NC_012943.1 2722661 2723059 R hypothetical protein complement(2722661..2723059) Mycobacterium tuberculosis KZN 1435 8160837 YP_003032450.1 CDS TBMG_02481 NC_012943.1 2723120 2723332 D hypothetical protein 2723120..2723332 Mycobacterium tuberculosis KZN 1435 8160838 YP_003032451.1 CDS TBMG_02482 NC_012943.1 2723546 2724163 D methyltransferase 2723546..2724163 Mycobacterium tuberculosis KZN 1435 8160839 YP_003032452.1 CDS TBMG_02483 NC_012943.1 2724236 2725525 R esterase lipL complement(2724236..2725525) Mycobacterium tuberculosis KZN 1435 8160840 YP_003032453.1 CDS TBMG_02484 NC_012943.1 2725578 2726582 R functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase complement(2725578..2726582) Mycobacterium tuberculosis KZN 1435 8160841 YP_003032454.1 CDS TBMG_02485 NC_012943.1 2726579 2726896 R toxin complement(2726579..2726896) Mycobacterium tuberculosis KZN 1435 8160842 YP_003032455.1 CDS TBMG_02486 NC_012943.1 2726893 2727195 R antitoxin complement(2726893..2727195) Mycobacterium tuberculosis KZN 1435 8160843 YP_003032456.1 CDS TBMG_02487 NC_012943.1 2727209 2729461 R MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase complement(2727209..2729461) Mycobacterium tuberculosis KZN 1435 8160844 YP_003032457.1 CDS TBMG_02488 NC_012943.1 2729462 2731333 R methylmalonyl-CoA mutase small subunit mutA complement(2729462..2731333) Mycobacterium tuberculosis KZN 1435 8160845 YP_003032458.1 CDS TBMG_02489 NC_012943.1 2731500 2732258 D hypothetical protein 2731500..2732258 Mycobacterium tuberculosis KZN 1435 8160846 YP_003032459.1 CDS TBMG_04062 NC_012943.1 2732476 2732739 R hypothetical protein complement(2732476..2732739) Mycobacterium tuberculosis KZN 1435 8160847 YP_003032460.1 CDS TBMG_02490 NC_012943.1 2732837 2734144 R hypothetical protein complement(2732837..2734144) Mycobacterium tuberculosis KZN 1435 8160848 YP_003032461.1 CDS TBMG_02491 NC_012943.1 2734294 2734524 R hypothetical protein complement(2734294..2734524) Mycobacterium tuberculosis KZN 1435 8160849 YP_003032462.1 CDS TBMG_02492 NC_012943.1 2734558 2734914 R hypothetical protein complement(2734558..2734914) Mycobacterium tuberculosis KZN 1435 8160850 YP_003032463.1 CDS TBMG_02493 NC_012943.1 2734924 2736069 R hypothetical protein complement(2734924..2736069) Mycobacterium tuberculosis KZN 1435 8160851 YP_003032464.1 CDS TBMG_02494 NC_012943.1 2736091 2736525 R hypothetical protein complement(2736091..2736525) Mycobacterium tuberculosis KZN 1435 8160852 YP_003032465.1 CDS TBMG_02495 NC_012943.1 2736541 2737449 D hypothetical protein 2736541..2737449 Mycobacterium tuberculosis KZN 1435 8160853 YP_003032466.1 CDS hemH NC_012943.1 2737415 2738449 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(2737415..2738449) Mycobacterium tuberculosis KZN 1435 8160854 YP_003032467.1 CDS TBMG_02497 NC_012943.1 2738455 2739264 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(2738455..2739264) Mycobacterium tuberculosis KZN 1435 8160855 YP_003032468.1 CDS TBMG_02498 NC_012943.1 2739283 2740026 R 3-oxoacyl-ACP reductase complement(2739283..2740026) Mycobacterium tuberculosis KZN 1435 8160856 YP_003032469.1 CDS TBMG_02499 NC_012943.1 2740167 2741009 D hypothetical protein 2740167..2741009 Mycobacterium tuberculosis KZN 1435 8160857 YP_003032470.1 CDS TBMG_02500 NC_012943.1 2741082 2742089 R hypothetical protein complement(2741082..2742089) Mycobacterium tuberculosis KZN 1435 8160858 YP_003032471.1 CDS TBMG_02501 NC_012943.1 2742100 2743053 R hypothetical protein complement(2742100..2743053) Mycobacterium tuberculosis KZN 1435 8160859 YP_003032472.1 CDS TBMG_02502 NC_012943.1 2743050 2744183 R transcriptional regulator moxR1 complement(2743050..2744183) Mycobacterium tuberculosis KZN 1435 8160860 YP_003032473.1 CDS TBMG_02503 NC_012943.1 2744322 2745083 R invasion-associated protein complement(2744322..2745083) Mycobacterium tuberculosis KZN 1435 8160861 YP_003032474.1 CDS TBMG_02504 NC_012943.1 2745058 2746476 R invasion-associated protein complement(2745058..2746476) Mycobacterium tuberculosis KZN 1435 8160862 YP_003032475.1 CDS TBMG_02505 NC_012943.1 2746702 2747262 R hypothetical protein complement(2746702..2747262) Mycobacterium tuberculosis KZN 1435 8160863 YP_003032476.1 CDS TBMG_02506 NC_012943.1 2747420 2750251 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 2747420..2750251 Mycobacterium tuberculosis KZN 1435 8160864 YP_003032477.1 CDS TBMG_02507 NC_012943.1 2750262 2750825 D transcriptional regulator 2750262..2750825 Mycobacterium tuberculosis KZN 1435 8160865 YP_003032478.1 CDS TBMG_02508 NC_012943.1 2750894 2751085 R transcriptional regulator complement(2750894..2751085) Mycobacterium tuberculosis KZN 1435 8160866 YP_003032479.1 CDS TBMG_02509 NC_012943.1 2751182 2752810 R macrolide-transport ATP-binding protein ABC transporter complement(2751182..2752810) Mycobacterium tuberculosis KZN 1435 8160867 YP_003032480.1 CDS TBMG_02510 NC_012943.1 2752846 2753703 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(2752846..2753703) Mycobacterium tuberculosis KZN 1435 8160868 YP_003032481.1 CDS TBMG_02511 NC_012943.1 2753725 2754096 R thioredoxin trxB1 complement(2753725..2754096) Mycobacterium tuberculosis KZN 1435 8160869 YP_003032482.1 CDS TBMG_02512 NC_012943.1 2754112 2754486 R thioredoxin trxA complement(2754112..2754486) Mycobacterium tuberculosis KZN 1435 8160870 YP_003032483.1 CDS TBMG_02513 NC_012943.1 2754530 2756503 R cation transporter P-type ATPase D ctpD complement(2754530..2756503) Mycobacterium tuberculosis KZN 1435 8160871 YP_003032484.1 CDS TBMG_02514 NC_012943.1 2756730 2757857 D PE-PGRS family protein 2756730..2757857 Mycobacterium tuberculosis KZN 1435 8160872 YP_003032485.1 CDS TBMG_02515 NC_012943.1 2757964 2759793 D acyl-CoA dehydrogenase 2757964..2759793 Mycobacterium tuberculosis KZN 1435 8160873 YP_003032486.1 CDS TBMG_02516 NC_012943.1 2759888 2760235 R hypothetical protein complement(2759888..2760235) Mycobacterium tuberculosis KZN 1435 8160874 YP_003032487.1 CDS TBMG_02517 NC_012943.1 2760210 2760698 R nitrogen fixation related protein complement(2760210..2760698) Mycobacterium tuberculosis KZN 1435 8160875 YP_003032488.1 CDS TBMG_02518 NC_012943.1 2760695 2761948 R cysteine desulfurase csd complement(2760695..2761948) Mycobacterium tuberculosis KZN 1435 8160876 YP_003032489.1 CDS TBMG_02519 NC_012943.1 2761950 2762750 R ABC transporter ATP-binding protein complement(2761950..2762750) Mycobacterium tuberculosis KZN 1435 8160877 YP_003032490.1 CDS TBMG_02520 NC_012943.1 2762747 2763940 R FeS assembly protein SufD complement(2762747..2763940) Mycobacterium tuberculosis KZN 1435 8160878 YP_003032491.1 CDS TBMG_02521 NC_012943.1 2763937 2766477 R hypothetical protein complement(2763937..2766477) Mycobacterium tuberculosis KZN 1435 8160879 YP_003032492.1 CDS TBMG_02522 NC_012943.1 2766474 2767280 R transcriptional regulator complement(2766474..2767280) Mycobacterium tuberculosis KZN 1435 8160880 YP_003032493.1 CDS TBMG_02523 NC_012943.1 2767328 2769103 D hypothetical protein 2767328..2769103 Mycobacterium tuberculosis KZN 1435 8160881 YP_003032494.1 CDS TBMG_02524 NC_012943.1 2769259 2770200 D antibiotic-transport ATP-binding protein ABC transporter 2769259..2770200 Mycobacterium tuberculosis KZN 1435 8160882 YP_003032495.1 CDS TBMG_02525 NC_012943.1 2770197 2770982 D antibiotic-transport membrane ABC transporter 2770197..2770982 Mycobacterium tuberculosis KZN 1435 8160883 YP_003032496.1 CDS TBMG_02526 NC_012943.1 2771094 2772026 D antibiotic-transport membrane ABC transporter 2771094..2772026 Mycobacterium tuberculosis KZN 1435 8160884 YP_003032497.1 CDS TBMG_02527 NC_012943.1 2771976 2772839 R hypothetical protein complement(2771976..2772839) Mycobacterium tuberculosis KZN 1435 8160885 YP_003032498.1 CDS TBMG_02528 NC_012943.1 2772838 2773845 D quinone reductase qor 2772838..2773845 Mycobacterium tuberculosis KZN 1435 8160887 YP_003032499.1 CDS TBMG_02529 NC_012943.1 2773873 2775171 R transcriptional activator complement(2773873..2775171) Mycobacterium tuberculosis KZN 1435 8160886 YP_003032500.1 CDS TBMG_02530 NC_012943.1 2775287 2777503 D PE-PGRS family protein 2775287..2777503 Mycobacterium tuberculosis KZN 1435 8160888 YP_003032501.1 CDS TBMG_04063 NC_012943.1 2777552 2778478 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(2777552..2778478) Mycobacterium tuberculosis KZN 1435 8160889 YP_003032502.1 CDS TBMG_02531 NC_012943.1 2778877 2783103 D hypothetical protein 2778877..2783103 Mycobacterium tuberculosis KZN 1435 8160890 YP_003032503.1 CDS TBMG_02532 NC_012943.1 2783542 2785644 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2783542..2785644 Mycobacterium tuberculosis KZN 1435 8160891 YP_003032504.1 CDS TBMG_02533 NC_012943.1 2785661 2786782 D catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 2785661..2786782 Mycobacterium tuberculosis KZN 1435 8160892 YP_003032505.1 CDS TBMG_02534 NC_012943.1 2786779 2788323 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2786779..2788323 Mycobacterium tuberculosis KZN 1435 8160893 YP_003032506.1 CDS TBMG_02535 NC_012943.1 2788376 2789287 D oxpp cycle protein opcA 2788376..2789287 Mycobacterium tuberculosis KZN 1435 8160894 YP_003032507.1 CDS TBMG_02536 NC_012943.1 2789284 2790027 D 6-phosphogluconolactonase 2789284..2790027 Mycobacterium tuberculosis KZN 1435 8160895 YP_003032508.1 CDS TBMG_02537 NC_012943.1 2790044 2790454 D hypothetical protein 2790044..2790454 Mycobacterium tuberculosis KZN 1435 8160896 YP_003032509.1 CDS TBMG_02538 NC_012943.1 2791049 2791534 D hypothetical protein 2791049..2791534 Mycobacterium tuberculosis KZN 1435 8160897 YP_003032510.1 CDS TBMG_02539 NC_012943.1 2791650 2793950 R biotin sulfoxide reductase bisC complement(2791650..2793950) Mycobacterium tuberculosis KZN 1435 8160898 YP_003032511.1 CDS TBMG_02540 NC_012943.1 2794057 2795475 D PE-PGRS family protein 2794057..2795475 Mycobacterium tuberculosis KZN 1435 8160899 YP_003032512.1 CDS TBMG_02541 NC_012943.1 2795614 2796027 R hypothetical protein complement(2795614..2796027) Mycobacterium tuberculosis KZN 1435 8160900 YP_003032513.1 CDS TBMG_02542 NC_012943.1 2796298 2796723 D hypothetical protein 2796298..2796723 Mycobacterium tuberculosis KZN 1435 8160901 YP_003032514.1 CDS tpiA NC_012943.1 2797335 2798120 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(2797335..2798120) Mycobacterium tuberculosis KZN 1435 8160902 YP_003032515.1 CDS pgk NC_012943.1 2798117 2799355 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(2798117..2799355) Mycobacterium tuberculosis KZN 1435 8160903 YP_003032516.1 CDS TBMG_02546 NC_012943.1 2799358 2800377 R glyceraldehyde-3-phosphate dehydrogenase complement(2799358..2800377) Mycobacterium tuberculosis KZN 1435 8160904 YP_003032517.1 CDS TBMG_02547 NC_012943.1 2800743 2801363 D hypothetical protein 2800743..2801363 Mycobacterium tuberculosis KZN 1435 8160905 YP_003032518.1 CDS TBMG_02548 NC_012943.1 2801456 2802271 R hypothetical protein complement(2801456..2802271) Mycobacterium tuberculosis KZN 1435 8160906 YP_003032519.1 CDS TBMG_04064 NC_012943.1 2802435 2803856 R dehydrogenase complement(2802435..2803856) Mycobacterium tuberculosis KZN 1435 8160907 YP_003032520.1 CDS TBMG_02549 NC_012943.1 2803853 2805622 R hypothetical protein complement(2803853..2805622) Mycobacterium tuberculosis KZN 1435 8160908 YP_003032521.1 CDS TBMG_02550 NC_012943.1 2805733 2807319 R PE family protein complement(2805733..2807319) Mycobacterium tuberculosis KZN 1435 8160909 YP_003032522.1 CDS TBMG_02551 NC_012943.1 2807559 2808827 R hypothetical protein complement(2807559..2808827) Mycobacterium tuberculosis KZN 1435 8160910 YP_003032523.1 CDS TBMG_02552 NC_012943.1 2808946 2809773 D hypothetical protein 2808946..2809773 Mycobacterium tuberculosis KZN 1435 8160911 YP_003032524.1 CDS TBMG_02553 NC_012943.1 2809777 2811384 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2809777..2811384 Mycobacterium tuberculosis KZN 1435 8160912 YP_003032525.1 CDS TBMG_02554 NC_012943.1 2811384 2812646 D esterase lipO 2811384..2812646 Mycobacterium tuberculosis KZN 1435 8160913 YP_003032526.1 CDS TBMG_02555 NC_012943.1 2812668 2814047 R hypothetical protein complement(2812668..2814047) Mycobacterium tuberculosis KZN 1435 8160914 YP_003032527.1 CDS TBMG_02556 NC_012943.1 2814051 2814812 D hypothetical protein 2814051..2814812 Mycobacterium tuberculosis KZN 1435 8160915 YP_003032528.1 CDS TBMG_02557 NC_012943.1 2814822 2815805 R hypothetical protein complement(2814822..2815805) Mycobacterium tuberculosis KZN 1435 8160916 YP_003032529.1 CDS TBMG_02558 NC_012943.1 2815796 2816824 R hypothetical protein complement(2815796..2816824) Mycobacterium tuberculosis KZN 1435 8160917 YP_003032530.1 CDS TBMG_02559 NC_012943.1 2816821 2817726 R hypothetical protein complement(2816821..2817726) Mycobacterium tuberculosis KZN 1435 8160918 YP_003032531.1 CDS uvrC NC_012943.1 2817723 2819663 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2817723..2819663) Mycobacterium tuberculosis KZN 1435 8160919 YP_003032532.1 CDS TBMG_02561 NC_012943.1 2819727 2820200 R hypothetical protein complement(2819727..2820200) Mycobacterium tuberculosis KZN 1435 8160920 YP_003032533.1 CDS TBMG_02562 NC_012943.1 2820380 2821066 R hypothetical protein complement(2820380..2821066) Mycobacterium tuberculosis KZN 1435 8160921 YP_003032534.1 CDS TBMG_02563 NC_012943.1 2821091 2821555 R hypothetical protein complement(2821091..2821555) Mycobacterium tuberculosis KZN 1435 8160922 YP_003032535.1 CDS ribH NC_012943.1 2821552 2822034 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(2821552..2822034) Mycobacterium tuberculosis KZN 1435 8160923 YP_003032536.1 CDS TBMG_02565 NC_012943.1 2822031 2823308 R bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein complement(2822031..2823308) Mycobacterium tuberculosis KZN 1435 8160924 YP_003032537.1 CDS TBMG_02566 NC_012943.1 2823413 2823814 R hypothetical protein complement(2823413..2823814) Mycobacterium tuberculosis KZN 1435 8160925 YP_003032538.1 CDS TBMG_02567 NC_012943.1 2823804 2824319 R hypothetical protein complement(2823804..2824319) Mycobacterium tuberculosis KZN 1435 8160926 YP_003032539.1 CDS TBMG_02568 NC_012943.1 2824533 2825138 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(2824533..2825138) Mycobacterium tuberculosis KZN 1435 8160927 YP_003032540.1 CDS TBMG_02569 NC_012943.1 2825214 2825933 D hypothetical protein 2825214..2825933 Mycobacterium tuberculosis KZN 1435 8160928 YP_003032541.1 CDS TBMG_02570 NC_012943.1 2825939 2827495 D hypothetical protein 2825939..2827495 Mycobacterium tuberculosis KZN 1435 8160929 YP_003032542.1 CDS TBMG_02571 NC_012943.1 2827492 2828511 R riboflavin biosynthesis protein ribG complement(2827492..2828511) Mycobacterium tuberculosis KZN 1435 8160930 YP_003032543.1 CDS TBMG_02572 NC_012943.1 2828508 2829206 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(2828508..2829206) Mycobacterium tuberculosis KZN 1435 8160931 YP_003032544.1 CDS TBMG_02573 NC_012943.1 2829231 2830604 R SUN protein complement(2829231..2830604) Mycobacterium tuberculosis KZN 1435 8160932 YP_003032545.1 CDS fmt NC_012943.1 2830601 2831539 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(2830601..2831539) Mycobacterium tuberculosis KZN 1435 8160933 YP_003032546.1 CDS TBMG_02575 NC_012943.1 2831736 2832560 D methyltransferase 2831736..2832560 Mycobacterium tuberculosis KZN 1435 8160934 YP_003032547.1 CDS TBMG_02576 NC_012943.1 2832632 2833159 R transcriptional regulator complement(2832632..2833159) Mycobacterium tuberculosis KZN 1435 8160935 YP_003032548.1 CDS TBMG_02577 NC_012943.1 2833283 2834107 D methyltransferase 2833283..2834107 Mycobacterium tuberculosis KZN 1435 8160936 YP_003032549.1 CDS TBMG_02578 NC_012943.1 2834125 2836092 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(2834125..2836092) Mycobacterium tuberculosis KZN 1435 8160937 YP_003032550.1 CDS TBMG_02579 NC_012943.1 2836173 2836958 R hypothetical protein complement(2836173..2836958) Mycobacterium tuberculosis KZN 1435 8160938 YP_003032551.1 CDS TBMG_02580 NC_012943.1 2836909 2837871 D lipase lipH 2836909..2837871 Mycobacterium tuberculosis KZN 1435 8160940 YP_003032552.1 CDS TBMG_02581 NC_012943.1 2837896 2838855 D lipase lipH 2837896..2838855 Mycobacterium tuberculosis KZN 1435 8160939 YP_003032553.1 CDS TBMG_02582 NC_012943.1 2838938 2839195 D antitoxin 2838938..2839195 Mycobacterium tuberculosis KZN 1435 8160941 YP_003032554.1 CDS TBMG_02583 NC_012943.1 2839192 2839593 D toxin 2839192..2839593 Mycobacterium tuberculosis KZN 1435 8160942 YP_003032555.1 CDS TBMG_02584 NC_012943.1 2839848 2841092 D PE-PGRS family protein 2839848..2841092 Mycobacterium tuberculosis KZN 1435 8160943 YP_003032556.1 CDS TBMG_04065 NC_012943.1 2841254 2841577 D PE-PGRS family protein 2841254..2841577 Mycobacterium tuberculosis KZN 1435 8160944 YP_003032557.1 CDS TBMG_02585 NC_012943.1 2841623 2842657 R transcriptional regulator complement(2841623..2842657) Mycobacterium tuberculosis KZN 1435 8160945 YP_003032558.1 CDS TBMG_02586 NC_012943.1 2842735 2844120 D cytochrome P450 132 cyp132 2842735..2844120 Mycobacterium tuberculosis KZN 1435 8160946 YP_003032559.1 CDS TBMG_02587 NC_012943.1 2844117 2845595 D monooxygenase 2844117..2845595 Mycobacterium tuberculosis KZN 1435 8160947 YP_003032560.1 CDS TBMG_02588 NC_012943.1 2845668 2846888 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(2845668..2846888) Mycobacterium tuberculosis KZN 1435 8160948 YP_003032561.1 CDS TBMG_02589 NC_012943.1 2847007 2848263 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(2847007..2848263) Mycobacterium tuberculosis KZN 1435 8160949 YP_003032562.1 CDS TBMG_02590 NC_012943.1 2848279 2848611 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(2848279..2848611) Mycobacterium tuberculosis KZN 1435 8160950 YP_003032563.1 CDS gmk NC_012943.1 2848677 2849330 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(2848677..2849330) Mycobacterium tuberculosis KZN 1435 8160951 YP_003032564.1 CDS TBMG_02592 NC_012943.1 2849438 2850010 R integration host factor mihF complement(2849438..2850010) Mycobacterium tuberculosis KZN 1435 8160952 YP_003032565.1 CDS TBMG_02593 NC_012943.1 2850316 2851935 R PPE family protein complement(2850316..2851935) Mycobacterium tuberculosis KZN 1435 8160953 YP_003032566.1 CDS TBMG_02594 NC_012943.1 2851932 2852240 R PE family protein complement(2851932..2852240) Mycobacterium tuberculosis KZN 1435 8160954 YP_003032567.1 CDS pyrF NC_012943.1 2852435 2853259 R type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(2852435..2853259) Mycobacterium tuberculosis KZN 1435 8160955 YP_003032568.1 CDS carB NC_012943.1 2853256 2856603 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(2853256..2856603) Mycobacterium tuberculosis KZN 1435 8160956 YP_003032569.1 CDS TBMG_02597 NC_012943.1 2856603 2857733 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(2856603..2857733) Mycobacterium tuberculosis KZN 1435 8160957 YP_003032570.1 CDS TBMG_02598 NC_012943.1 2857730 2858227 R hypothetical protein complement(2857730..2858227) Mycobacterium tuberculosis KZN 1435 8160958 YP_003032571.1 CDS pyrC NC_012943.1 2858224 2859516 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(2858224..2859516) Mycobacterium tuberculosis KZN 1435 8160959 YP_003032572.1 CDS pyrB NC_012943.1 2859513 2860472 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(2859513..2860472) Mycobacterium tuberculosis KZN 1435 8160960 YP_003032573.1 CDS TBMG_02601 NC_012943.1 2860469 2861050 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase complement(2860469..2861050) Mycobacterium tuberculosis KZN 1435 8160961 YP_003032574.1 CDS TBMG_02602 NC_012943.1 2861049 2862476 D hypothetical protein 2861049..2862476 Mycobacterium tuberculosis KZN 1435 8164494 YP_003032575.1 CDS TBMG_02603 NC_012943.1 2862487 2863125 D transferase 2862487..2863125 Mycobacterium tuberculosis KZN 1435 8160962 YP_003032576.1 CDS TBMG_02604 NC_012943.1 2863063 2864556 R hypothetical protein complement(2863063..2864556) Mycobacterium tuberculosis KZN 1435 8164495 YP_003032577.1 CDS TBMG_02605 NC_012943.1 2864553 2865872 R hypothetical protein complement(2864553..2865872) Mycobacterium tuberculosis KZN 1435 8162054 YP_003032578.1 CDS TBMG_02606 NC_012943.1 2866174 2866632 D hypothetical protein 2866174..2866632 Mycobacterium tuberculosis KZN 1435 8162166 YP_003032579.1 CDS TBMG_02607 NC_012943.1 2866712 2867692 R glycolipid sulfotransferase complement(2866712..2867692) Mycobacterium tuberculosis KZN 1435 8162167 YP_003032580.1 CDS TBMG_02608 NC_012943.1 2867698 2868879 R hypothetical protein complement(2867698..2868879) Mycobacterium tuberculosis KZN 1435 8162168 YP_003032581.1 CDS TBMG_02609 NC_012943.1 2868876 2870345 R hypothetical protein complement(2868876..2870345) Mycobacterium tuberculosis KZN 1435 8162169 YP_003032582.1 CDS TBMG_02610 NC_012943.1 2870541 2871326 R hypothetical protein complement(2870541..2871326) Mycobacterium tuberculosis KZN 1435 8162170 YP_003032583.1 CDS TBMG_02611 NC_012943.1 2871629 2872834 D hypothetical protein 2871629..2872834 Mycobacterium tuberculosis KZN 1435 8162171 YP_003032584.1 CDS TBMG_04066 NC_012943.1 2872906 2873166 R hypothetical protein complement(2872906..2873166) Mycobacterium tuberculosis KZN 1435 8162172 YP_003032585.1 CDS TBMG_04067 NC_012943.1 2873135 2873956 R hypothetical protein complement(2873135..2873956) Mycobacterium tuberculosis KZN 1435 8162173 YP_003032586.1 CDS TBMG_02613 NC_012943.1 2874177 2874563 D anti-anti-sigma factor rsfA 2874177..2874563 Mycobacterium tuberculosis KZN 1435 8162174 YP_003032587.1 CDS TBMG_02614 NC_012943.1 2874702 2876663 D hypothetical protein 2874702..2876663 Mycobacterium tuberculosis KZN 1435 8162175 YP_003032588.1 CDS TBMG_02615 NC_012943.1 2876954 2877739 D hypothetical protein 2876954..2877739 Mycobacterium tuberculosis KZN 1435 8162176 YP_003032589.1 CDS TBMG_02616 NC_012943.1 2877736 2878398 D hypothetical protein 2877736..2878398 Mycobacterium tuberculosis KZN 1435 8162177 YP_003032590.1 CDS TBMG_02617 NC_012943.1 2878713 2879903 D PPE family protein 2878713..2879903 Mycobacterium tuberculosis KZN 1435 8162178 YP_003032591.1 CDS TBMG_02618 NC_012943.1 2879976 2880998 R oxidoreductase complement(2879976..2880998) Mycobacterium tuberculosis KZN 1435 8162179 YP_003032592.1 CDS TBMG_04068 NC_012943.1 2881137 2881373 D hypothetical protein 2881137..2881373 Mycobacterium tuberculosis KZN 1435 8162180 YP_003032593.1 CDS TBMG_02619 NC_012943.1 2881421 2882173 R transcriptional regulator complement(2881421..2882173) Mycobacterium tuberculosis KZN 1435 8162181 YP_003032594.1 CDS TBMG_04069 NC_012943.1 2882255 2884867 R transcriptional regulator complement(2882255..2884867) Mycobacterium tuberculosis KZN 1435 8162182 YP_003032595.1 CDS TBMG_04070 NC_012943.1 2884836 2885735 R transcriptional regulator complement(2884836..2885735) Mycobacterium tuberculosis KZN 1435 8162183 YP_003032596.1 CDS TBMG_02621 NC_012943.1 2886131 2887054 D hypothetical protein 2886131..2887054 Mycobacterium tuberculosis KZN 1435 8162184 YP_003032597.1 CDS TBMG_02622 NC_012943.1 2887527 2888318 D hypothetical protein 2887527..2888318 Mycobacterium tuberculosis KZN 1435 8162185 YP_003032598.1 CDS TBMG_02623 NC_012943.1 2888315 2890462 D hypothetical protein 2888315..2890462 Mycobacterium tuberculosis KZN 1435 8162186 YP_003032599.1 CDS TBMG_02624 NC_012943.1 2890471 2892342 D hypothetical protein 2890471..2892342 Mycobacterium tuberculosis KZN 1435 8162187 YP_003032600.1 CDS TBMG_02625 NC_012943.1 2892362 2893147 D transcriptional regulator 2892362..2893147 Mycobacterium tuberculosis KZN 1435 8162188 YP_003032601.1 CDS TBMG_02626 NC_012943.1 2893213 2893584 R hypothetical protein complement(2893213..2893584) Mycobacterium tuberculosis KZN 1435 8162189 YP_003032602.1 CDS TBMG_02627 NC_012943.1 2893787 2894116 R hypothetical protein complement(2893787..2894116) Mycobacterium tuberculosis KZN 1435 8162190 YP_003032603.1 CDS fabG NC_012943.1 2894113 2894856 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(2894113..2894856) Mycobacterium tuberculosis KZN 1435 8162191 YP_003032604.1 CDS TBMG_02629 NC_012943.1 2894985 2896724 R drugs-transport transmembrane ATP-binding protein ABC transporter complement(2894985..2896724) Mycobacterium tuberculosis KZN 1435 8162192 YP_003032605.1 CDS TBMG_02630 NC_012943.1 2896721 2899300 R drugs-transport transmembrane ATP-binding protein ABC transporter complement(2896721..2899300) Mycobacterium tuberculosis KZN 1435 8162193 YP_003032606.1 CDS TBMG_02631 NC_012943.1 2899742 2900374 D hypothetical protein 2899742..2900374 Mycobacterium tuberculosis KZN 1435 8162195 YP_003032607.1 CDS TBMG_02632 NC_012943.1 2900341 2901501 R acyl-CoA dehydrogenase complement(2900341..2901501) Mycobacterium tuberculosis KZN 1435 8162196 YP_003032608.1 CDS TBMG_02633 NC_012943.1 2901501 2903066 R converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; long-chain fatty acid--ACP ligase complement(2901501..2903066) Mycobacterium tuberculosis KZN 1435 8162197 YP_003032609.1 CDS TBMG_02634 NC_012943.1 2903059 2903379 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(2903059..2903379) Mycobacterium tuberculosis KZN 1435 8162198 YP_003032610.1 CDS TBMG_02635 NC_012943.1 2903424 2903804 D hypothetical protein 2903424..2903804 Mycobacterium tuberculosis KZN 1435 8162199 YP_003032611.1 CDS TBMG_02636 NC_012943.1 2903801 2904163 D hypothetical protein 2903801..2904163 Mycobacterium tuberculosis KZN 1435 8162200 YP_003032612.1 CDS TBMG_02637 NC_012943.1 2904160 2904774 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase complement(2904160..2904774) Mycobacterium tuberculosis KZN 1435 8162201 YP_003032613.1 CDS rph NC_012943.1 2904813 2905592 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(2904813..2905592) Mycobacterium tuberculosis KZN 1435 8162202 YP_003032614.1 CDS TBMG_02639 NC_012943.1 2905609 2906430 R hypothetical protein complement(2905609..2906430) Mycobacterium tuberculosis KZN 1435 8162203 YP_003032615.1 CDS TBMG_02640 NC_012943.1 2906457 2907272 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(2906457..2907272) Mycobacterium tuberculosis KZN 1435 8162204 YP_003032616.1 CDS TBMG_02641 NC_012943.1 2907269 2907991 R hypothetical protein complement(2907269..2907991) Mycobacterium tuberculosis KZN 1435 8162205 YP_003032617.1 CDS TBMG_02642 NC_012943.1 2907982 2908953 R cysteine synthase B cysM complement(2907982..2908953) Mycobacterium tuberculosis KZN 1435 8162206 YP_003032618.1 CDS TBMG_02643 NC_012943.1 2908963 2909244 R hypothetical protein complement(2908963..2909244) Mycobacterium tuberculosis KZN 1435 8162207 YP_003032619.1 CDS TBMG_02644 NC_012943.1 2909266 2909706 R hypothetical protein complement(2909266..2909706) Mycobacterium tuberculosis KZN 1435 8162208 YP_003032620.1 CDS TBMG_02645 NC_012943.1 2909714 2910748 R hydrolase complement(2909714..2910748) Mycobacterium tuberculosis KZN 1435 8162209 YP_003032621.1 CDS TBMG_02646 NC_012943.1 2910765 2911421 R transcriptional regulator complement(2910765..2911421) Mycobacterium tuberculosis KZN 1435 8162210 YP_003032622.1 CDS clpS NC_012943.1 2911381 2911686 R involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS complement(2911381..2911686) Mycobacterium tuberculosis KZN 1435 8162211 YP_003032623.1 CDS TBMG_02648 NC_012943.1 2911788 2913134 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2911788..2913134 Mycobacterium tuberculosis KZN 1435 8162212 YP_003032624.1 CDS TBMG_02649 NC_012943.1 2913158 2915152 D ATP-dependent helicase dinG 2913158..2915152 Mycobacterium tuberculosis KZN 1435 8162213 YP_003032625.1 CDS TBMG_02650 NC_012943.1 2915192 2917783 R glycogen phosphorylase glgP complement(2915192..2917783) Mycobacterium tuberculosis KZN 1435 8162214 YP_003032626.1 CDS TBMG_02651 NC_012943.1 2917922 2920027 D glucanase glgE 2917922..2920027 Mycobacterium tuberculosis KZN 1435 8162215 YP_003032627.1 CDS TBMG_02652 NC_012943.1 2920035 2922230 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 2920035..2922230 Mycobacterium tuberculosis KZN 1435 8162216 YP_003032628.1 CDS TBMG_04071 NC_012943.1 2922382 2924193 D PE-PGRS family protein 2922382..2924193 Mycobacterium tuberculosis KZN 1435 8162217 YP_003032629.1 CDS TBMG_02655 NC_012943.1 2924272 2925186 R thioredoxin complement(2924272..2925186) Mycobacterium tuberculosis KZN 1435 8162218 YP_003032630.1 CDS TBMG_02656 NC_012943.1 2925316 2926485 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(2925316..2926485) Mycobacterium tuberculosis KZN 1435 8162219 YP_003032631.1 CDS TBMG_04072 NC_012943.1 2926397 2926579 D hypothetical protein 2926397..2926579 Mycobacterium tuberculosis KZN 1435 8162221 YP_003032632.1 CDS TBMG_02657 NC_012943.1 2926576 2927034 D hypothetical protein 2926576..2927034 Mycobacterium tuberculosis KZN 1435 8162220 YP_003032633.1 CDS TBMG_02658 NC_012943.1 2927069 2927365 R hypothetical protein complement(2927069..2927365) Mycobacterium tuberculosis KZN 1435 8162222 YP_003032634.1 CDS TBMG_02659 NC_012943.1 2927388 2928068 R hypothetical protein complement(2927388..2928068) Mycobacterium tuberculosis KZN 1435 8162223 YP_003032635.1 CDS TBMG_02660 NC_012943.1 2928130 2929833 D adenylate cyclase 2928130..2929833 Mycobacterium tuberculosis KZN 1435 8162224 YP_003032636.1 CDS TBMG_02661 NC_012943.1 2929846 2931453 D adenylate cyclase 2929846..2931453 Mycobacterium tuberculosis KZN 1435 8162225 YP_003032637.1 CDS TBMG_02662 NC_012943.1 2931523 2933148 D adenylate cyclase 2931523..2933148 Mycobacterium tuberculosis KZN 1435 8162226 YP_003032638.1 CDS TBMG_02663 NC_012943.1 2933229 2934719 D ada regulatory protein alkA 2933229..2934719 Mycobacterium tuberculosis KZN 1435 8162227 YP_003032639.1 CDS TBMG_02664 NC_012943.1 2934716 2935213 D methylated-DNA-protein-cysteine methyltransferase ogt 2934716..2935213 Mycobacterium tuberculosis KZN 1435 8162228 YP_003032640.1 CDS TBMG_02665 NC_012943.1 2940771 2942027 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(2940771..2942027) Mycobacterium tuberculosis KZN 1435 8161235 YP_003032641.1 CDS TBMG_02666 NC_012943.1 2942096 2942677 D ATP:cob(I)alamin adenosyltransferase 2942096..2942677 Mycobacterium tuberculosis KZN 1435 8162230 YP_003032642.1 CDS TBMG_02667 NC_012943.1 2942843 2944177 D transposase 2942843..2944177 Mycobacterium tuberculosis KZN 1435 8162231 YP_003032643.1 CDS TBMG_02668 NC_012943.1 2944217 2944660 R hypothetical protein complement(2944217..2944660) Mycobacterium tuberculosis KZN 1435 8162232 YP_003032644.1 CDS atpC NC_012943.1 2944668 2945099 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(2944668..2945099) Mycobacterium tuberculosis KZN 1435 8162233 YP_003032645.1 CDS TBMG_02670 NC_012943.1 2945047 2946507 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(2945047..2946507) Mycobacterium tuberculosis KZN 1435 8162234 YP_003032646.1 CDS TBMG_02671 NC_012943.1 2946547 2947464 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(2946547..2947464) Mycobacterium tuberculosis KZN 1435 8162235 YP_003032647.1 CDS TBMG_02672 NC_012943.1 2947471 2949120 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(2947471..2949120) Mycobacterium tuberculosis KZN 1435 8162236 YP_003032648.1 CDS TBMG_02673 NC_012943.1 2949165 2950505 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(2949165..2950505) Mycobacterium tuberculosis KZN 1435 8162237 YP_003032649.1 CDS TBMG_02674 NC_012943.1 2950512 2951027 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(2950512..2951027) Mycobacterium tuberculosis KZN 1435 8162238 YP_003032650.1 CDS TBMG_02675 NC_012943.1 2951058 2951345 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(2951058..2951345) Mycobacterium tuberculosis KZN 1435 8162239 YP_003032651.1 CDS TBMG_02676 NC_012943.1 2951352 2952104 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(2951352..2952104) Mycobacterium tuberculosis KZN 1435 8162240 YP_003032652.1 CDS TBMG_02677 NC_012943.1 2952097 2952582 R hypothetical protein complement(2952097..2952582) Mycobacterium tuberculosis KZN 1435 8162241 YP_003032653.1 CDS TBMG_02678 NC_012943.1 2952839 2954053 R undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe complement(2952839..2954053) Mycobacterium tuberculosis KZN 1435 8162242 YP_003032654.1 CDS TBMG_02679 NC_012943.1 2954137 2954790 R Sua5/YciO/YrdC/YwlC family protein complement(2954137..2954790) Mycobacterium tuberculosis KZN 1435 8162243 YP_003032655.1 CDS TBMG_02680 NC_012943.1 2954806 2955783 R hypothetical protein complement(2954806..2955783) Mycobacterium tuberculosis KZN 1435 8162244 YP_003032656.1 CDS prfA NC_012943.1 2955780 2956853 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(2955780..2956853) Mycobacterium tuberculosis KZN 1435 8162245 YP_003032657.1 CDS rpmE NC_012943.1 2956943 2957185 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(2956943..2957185) Mycobacterium tuberculosis KZN 1435 8161126 YP_003032658.1 CDS TBMG_02683 NC_012943.1 2957336 2959144 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(2957336..2959144) Mycobacterium tuberculosis KZN 1435 8161127 YP_003032659.1 CDS TBMG_02684 NC_012943.1 2959401 2960351 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(2959401..2960351) Mycobacterium tuberculosis KZN 1435 8161128 YP_003032660.1 CDS TBMG_02685 NC_012943.1 2960512 2961594 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(2960512..2961594) Mycobacterium tuberculosis KZN 1435 8161129 YP_003032661.1 CDS TBMG_02686 NC_012943.1 2961591 2962916 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(2961591..2962916) Mycobacterium tuberculosis KZN 1435 8161130 YP_003032662.1 CDS TBMG_02687 NC_012943.1 2962920 2964263 R diaminopimelate decarboxylase lysA complement(2962920..2964263) Mycobacterium tuberculosis KZN 1435 8161131 YP_003032663.1 CDS argS NC_012943.1 2964260 2965912 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(2964260..2965912) Mycobacterium tuberculosis KZN 1435 8161132 YP_003032664.1 CDS TBMG_02689 NC_012943.1 2966457 2966792 D hypothetical protein 2966457..2966792 Mycobacterium tuberculosis KZN 1435 8161134 YP_003032665.1 CDS TBMG_02690 NC_012943.1 2966919 2967233 R hypothetical protein complement(2966919..2967233) Mycobacterium tuberculosis KZN 1435 8161135 YP_003032666.1 CDS TBMG_02691 NC_012943.1 2967244 2968809 D hypothetical protein 2967244..2968809 Mycobacterium tuberculosis KZN 1435 8161136 YP_003032667.1 CDS TBMG_02692 NC_012943.1 2968892 2969524 R hypothetical protein complement(2968892..2969524) Mycobacterium tuberculosis KZN 1435 8161137 YP_003032668.1 CDS TBMG_02693 NC_012943.1 2969573 2970943 R hypothetical protein complement(2969573..2970943) Mycobacterium tuberculosis KZN 1435 8161138 YP_003032669.1 CDS TBMG_02694 NC_012943.1 2971001 2971486 R hypothetical protein complement(2971001..2971486) Mycobacterium tuberculosis KZN 1435 8161139 YP_003032670.1 CDS TBMG_02695 NC_012943.1 2971540 2973384 R in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein complement(2971540..2973384) Mycobacterium tuberculosis KZN 1435 8161140 YP_003032671.1 CDS TBMG_02696 NC_012943.1 2973384 2974382 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(2973384..2974382) Mycobacterium tuberculosis KZN 1435 8161141 YP_003032672.1 CDS TBMG_02697 NC_012943.1 2974476 2974967 R hypothetical protein complement(2974476..2974967) Mycobacterium tuberculosis KZN 1435 8161142 YP_003032673.1 CDS TBMG_02698 NC_012943.1 2975174 2976151 D hypothetical protein 2975174..2976151 Mycobacterium tuberculosis KZN 1435 8161143 YP_003032674.1 CDS TBMG_02699 NC_012943.1 2976148 2977023 D hypothetical protein 2976148..2977023 Mycobacterium tuberculosis KZN 1435 8161144 YP_003032675.1 CDS TBMG_02700 NC_012943.1 2977020 2978858 D peptide ABC transporter ATP-binding protein 2977020..2978858 Mycobacterium tuberculosis KZN 1435 8161145 YP_003032676.1 CDS TBMG_02701 NC_012943.1 2978851 2980626 D periplasmic oligopeptide-binding lipoprotein oppA 2978851..2980626 Mycobacterium tuberculosis KZN 1435 8161146 YP_003032677.1 CDS TBMG_02702 NC_012943.1 2980643 2982229 R dehydrogenase FAD flavoprotein gmc oxidoreductase complement(2980643..2982229) Mycobacterium tuberculosis KZN 1435 8161147 YP_003032678.1 CDS TBMG_02703 NC_012943.1 2982250 2984877 R hypothetical protein complement(2982250..2984877) Mycobacterium tuberculosis KZN 1435 8161148 YP_003032679.1 CDS TBMG_02704 NC_012943.1 2984874 2986127 R hypothetical protein complement(2984874..2986127) Mycobacterium tuberculosis KZN 1435 8161149 YP_003032680.1 CDS TBMG_02705 NC_012943.1 2986347 2986853 D hypothetical protein 2986347..2986853 Mycobacterium tuberculosis KZN 1435 8161150 YP_003032681.1 CDS TBMG_02706 NC_012943.1 2986998 2987540 R hypothetical protein complement(2986998..2987540) Mycobacterium tuberculosis KZN 1435 8161151 YP_003032682.1 CDS TBMG_02707 NC_012943.1 2987537 2988094 R hypothetical protein complement(2987537..2988094) Mycobacterium tuberculosis KZN 1435 8161152 YP_003032683.1 CDS TBMG_02708 NC_012943.1 2988241 2989989 D drugs-transport transmembrane ATP-binding protein ABC transporter 2988241..2989989 Mycobacterium tuberculosis KZN 1435 8161153 YP_003032684.1 CDS TBMG_02709 NC_012943.1 2989986 2991881 D drugs-transport transmembrane ATP-binding protein ABC transporter 2989986..2991881 Mycobacterium tuberculosis KZN 1435 8161154 YP_003032685.1 CDS TBMG_02710 NC_012943.1 2991989 2992330 D hypothetical protein 2991989..2992330 Mycobacterium tuberculosis KZN 1435 8161155 YP_003032686.1 CDS TBMG_02711 NC_012943.1 2992504 2993277 D hypothetical protein 2992504..2993277 Mycobacterium tuberculosis KZN 1435 8161156 YP_003032687.1 CDS TBMG_02712 NC_012943.1 2993338 2993712 D hypothetical protein 2993338..2993712 Mycobacterium tuberculosis KZN 1435 8161157 YP_003032688.1 CDS TBMG_02713 NC_012943.1 2993935 2994633 D hypothetical protein 2993935..2994633 Mycobacterium tuberculosis KZN 1435 8161158 YP_003032689.1 CDS TBMG_02714 NC_012943.1 2994944 2996110 D transcriptional regulator embR 2994944..2996110 Mycobacterium tuberculosis KZN 1435 8161159 YP_003032690.1 CDS TBMG_02715 NC_012943.1 2996451 2998331 D Ser/Thr protein kinase 2996451..2998331 Mycobacterium tuberculosis KZN 1435 8161160 YP_003032691.1 CDS TBMG_02716 NC_012943.1 2998351 2999031 R hypothetical protein complement(2998351..2999031) Mycobacterium tuberculosis KZN 1435 8161161 YP_003032692.1 CDS TBMG_02717 NC_012943.1 2999204 3000397 R adenylyl cyclase complement(2999204..3000397) Mycobacterium tuberculosis KZN 1435 8161162 YP_003032693.1 CDS TBMG_02718 NC_012943.1 3000472 3001860 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(3000472..3001860) Mycobacterium tuberculosis KZN 1435 8161163 YP_003032694.1 CDS TBMG_02719 NC_012943.1 3001919 3002353 D hypothetical protein 3001919..3002353 Mycobacterium tuberculosis KZN 1435 8161164 YP_003032695.1 CDS TBMG_02720 NC_012943.1 3002334 3002807 D hypothetical protein 3002334..3002807 Mycobacterium tuberculosis KZN 1435 8161165 YP_003032696.1 CDS TBMG_02721 NC_012943.1 3002933 3004060 R hypothetical protein complement(3002933..3004060) Mycobacterium tuberculosis KZN 1435 8161166 YP_003032697.1 CDS TBMG_02722 NC_012943.1 3004053 3004952 R hypothetical protein complement(3004053..3004952) Mycobacterium tuberculosis KZN 1435 8161167 YP_003032698.1 CDS TBMG_02723 NC_012943.1 3004951 3006210 D membrane transporter 3004951..3006210 Mycobacterium tuberculosis KZN 1435 8161169 YP_003032699.1 CDS TBMG_02724 NC_012943.1 3006207 3007574 D oxidoreductase 3006207..3007574 Mycobacterium tuberculosis KZN 1435 8161168 YP_003032700.1 CDS TBMG_02725 NC_012943.1 3007700 3008905 D cytochrome P450 130 cyp130 3007700..3008905 Mycobacterium tuberculosis KZN 1435 8161170 YP_003032701.1 CDS TBMG_02726 NC_012943.1 3008905 3009513 D transcriptional regulator 3008905..3009513 Mycobacterium tuberculosis KZN 1435 8161171 YP_003032702.1 CDS TBMG_02727 NC_012943.1 3009482 3010633 R acyltransferase complement(3009482..3010633) Mycobacterium tuberculosis KZN 1435 8161172 YP_003032703.1 CDS TBMG_02728 NC_012943.1 3010630 3012321 R cold shock deaD-box protein A deaD complement(3010630..3012321) Mycobacterium tuberculosis KZN 1435 8161173 YP_003032704.1 CDS TBMG_02729 NC_012943.1 3012387 3012995 D hypothetical protein 3012387..3012995 Mycobacterium tuberculosis KZN 1435 8161174 YP_003032705.1 CDS TBMG_02730 NC_012943.1 3013051 3016470 D hypothetical protein 3013051..3016470 Mycobacterium tuberculosis KZN 1435 8161175 YP_003032706.1 CDS TBMG_02731 NC_012943.1 3016373 3018112 R hypothetical protein complement(3016373..3018112) Mycobacterium tuberculosis KZN 1435 8161176 YP_003032707.1 CDS TBMG_02732 NC_012943.1 3018309 3019097 D hypothetical protein 3018309..3019097 Mycobacterium tuberculosis KZN 1435 8161177 YP_003032708.1 CDS kgd NC_012943.1 3019239 3022934 D kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase 3019239..3022934 Mycobacterium tuberculosis KZN 1435 8161178 YP_003032709.1 CDS TBMG_02734 NC_012943.1 3023047 3023316 D antitoxin 3023047..3023316 Mycobacterium tuberculosis KZN 1435 8161179 YP_003032710.1 CDS TBMG_02735 NC_012943.1 3023313 3023606 D toxin 3023313..3023606 Mycobacterium tuberculosis KZN 1435 8161180 YP_003032711.1 CDS TBMG_02736 NC_012943.1 3023663 3024493 D short-chain type dehydrogenase/reductase 3023663..3024493 Mycobacterium tuberculosis KZN 1435 8161181 YP_003032712.1 CDS TBMG_02737 NC_012943.1 3024574 3025434 R hypothetical protein complement(3024574..3025434) Mycobacterium tuberculosis KZN 1435 8161182 YP_003032713.1 CDS TBMG_02738 NC_012943.1 3025542 3027302 D PE-PGRS family protein 3025542..3027302 Mycobacterium tuberculosis KZN 1435 8161183 YP_003032714.1 CDS TBMG_02739 NC_012943.1 3027325 3027756 R toxin complement(3027325..3027756) Mycobacterium tuberculosis KZN 1435 8161184 YP_003032715.1 CDS TBMG_02740 NC_012943.1 3027753 3028013 R antitoxin complement(3027753..3028013) Mycobacterium tuberculosis KZN 1435 8161185 YP_003032716.1 CDS TBMG_02741 NC_012943.1 3028089 3029078 R catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase complement(3028089..3029078) Mycobacterium tuberculosis KZN 1435 8161186 YP_003032717.1 CDS TBMG_02742 NC_012943.1 3029249 3030349 D hypothetical protein 3029249..3030349 Mycobacterium tuberculosis KZN 1435 8161187 YP_003032718.1 CDS TBMG_02743 NC_012943.1 3030426 3031607 R sugar ABC transporter complement(3030426..3031607) Mycobacterium tuberculosis KZN 1435 8161188 YP_003032719.1 CDS TBMG_02744 NC_012943.1 3031612 3032436 R hypothetical protein complement(3031612..3032436) Mycobacterium tuberculosis KZN 1435 8161189 YP_003032720.1 CDS TBMG_02745 NC_012943.1 3032441 3033364 R hypothetical protein complement(3032441..3033364) Mycobacterium tuberculosis KZN 1435 8161190 YP_003032721.1 CDS TBMG_02746 NC_012943.1 3033361 3034767 R sugar-binding lipoprotein lpqY complement(3033361..3034767) Mycobacterium tuberculosis KZN 1435 8161191 YP_003032722.1 CDS TBMG_02747 NC_012943.1 3034788 3035315 R hypothetical protein complement(3034788..3035315) Mycobacterium tuberculosis KZN 1435 8161192 YP_003032723.1 CDS TBMG_02748 NC_012943.1 3035456 3036061 D hypothetical protein 3035456..3036061 Mycobacterium tuberculosis KZN 1435 8161193 YP_003032724.1 CDS TBMG_02749 NC_012943.1 3036123 3037430 D hypothetical protein 3036123..3037430 Mycobacterium tuberculosis KZN 1435 8161194 YP_003032725.1 CDS TBMG_02750 NC_012943.1 3037427 3037969 D hypothetical protein 3037427..3037969 Mycobacterium tuberculosis KZN 1435 8161195 YP_003032726.1 CDS TBMG_02751 NC_012943.1 3038094 3039329 D hypothetical protein 3038094..3039329 Mycobacterium tuberculosis KZN 1435 8161196 YP_003032727.1 CDS TBMG_02752 NC_012943.1 3039342 3040514 D hypothetical protein 3039342..3040514 Mycobacterium tuberculosis KZN 1435 8161197 YP_003032728.1 CDS TBMG_02753 NC_012943.1 3040589 3040762 R hypothetical protein complement(3040589..3040762) Mycobacterium tuberculosis KZN 1435 8161198 YP_003032729.1 CDS TBMG_02754 NC_012943.1 3040814 3041371 R hypothetical protein complement(3040814..3041371) Mycobacterium tuberculosis KZN 1435 8161199 YP_003032730.1 CDS TBMG_02755 NC_012943.1 3041466 3041999 D hypothetical protein 3041466..3041999 Mycobacterium tuberculosis KZN 1435 8161200 YP_003032731.1 CDS TBMG_02756 NC_012943.1 3041996 3043459 D hypothetical protein 3041996..3043459 Mycobacterium tuberculosis KZN 1435 8161201 YP_003032732.1 CDS TBMG_02757 NC_012943.1 3043570 3044400 D hypothetical protein 3043570..3044400 Mycobacterium tuberculosis KZN 1435 8161202 YP_003032733.1 CDS TBMG_02758 NC_012943.1 3044433 3044828 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(3044433..3044828) Mycobacterium tuberculosis KZN 1435 8161203 YP_003032734.1 CDS TBMG_02759 NC_012943.1 3044830 3045918 R truncated CDS; heat shock protein HtrA complement(3044830..3045918) Mycobacterium tuberculosis KZN 1435 8161204 YP_003032735.1 CDS TBMG_02760 NC_012943.1 3046485 3047144 R RNA polymerase sigma-70 factor complement(3046485..3047144) Mycobacterium tuberculosis KZN 1435 8161205 YP_003032736.1 CDS TBMG_02761 NC_012943.1 3047107 3047880 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence; RNA polymerase sigma factor SigE complement(3047107..3047880) Mycobacterium tuberculosis KZN 1435 8161206 YP_003032737.1 CDS TBMG_02762 NC_012943.1 3048047 3048790 D methyltransferase 3048047..3048790 Mycobacterium tuberculosis KZN 1435 8161207 YP_003032738.1 CDS TBMG_02763 NC_012943.1 3048932 3049570 D transcriptional regulator 3048932..3049570 Mycobacterium tuberculosis KZN 1435 8161208 YP_003032739.1 CDS TBMG_02764 NC_012943.1 3049560 3050495 D tetronasin-transport ATP-binding protein ABC transporter 3049560..3050495 Mycobacterium tuberculosis KZN 1435 8163795 YP_003032740.1 CDS TBMG_02765 NC_012943.1 3050492 3052138 D hypothetical protein 3050492..3052138 Mycobacterium tuberculosis KZN 1435 8163796 YP_003032741.1 CDS TBMG_02766 NC_012943.1 3052147 3052821 D hypothetical protein 3052147..3052821 Mycobacterium tuberculosis KZN 1435 8163797 YP_003032742.1 CDS TBMG_02767 NC_012943.1 3052849 3054534 D hypothetical protein 3052849..3054534 Mycobacterium tuberculosis KZN 1435 8163798 YP_003032743.1 CDS TBMG_02768 NC_012943.1 3054668 3055000 D PE family protein 3054668..3055000 Mycobacterium tuberculosis KZN 1435 8163799 YP_003032744.1 CDS glgC NC_012943.1 3055243 3056457 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3055243..3056457) Mycobacterium tuberculosis KZN 1435 8163800 YP_003032745.1 CDS TBMG_02770 NC_012943.1 3056632 3057795 D glycosyltransferase 3056632..3057795 Mycobacterium tuberculosis KZN 1435 8163801 YP_003032746.1 CDS TBMG_02771 NC_012943.1 3057823 3058050 R hypothetical protein complement(3057823..3058050) Mycobacterium tuberculosis KZN 1435 8163802 YP_003032747.1 CDS TBMG_02772 NC_012943.1 3058157 3058771 R DNA-3-methyladenine glycosylase I tagA complement(3058157..3058771) Mycobacterium tuberculosis KZN 1435 8163803 YP_003032748.1 CDS TBMG_02773 NC_012943.1 3058768 3059136 R hypothetical protein complement(3058768..3059136) Mycobacterium tuberculosis KZN 1435 8163804 YP_003032749.1 CDS TBMG_02774 NC_012943.1 3059175 3060149 R glucosyl-3-phosphoglycerate synthase complement(3059175..3060149) Mycobacterium tuberculosis KZN 1435 8163805 YP_003032750.1 CDS TBMG_02775 NC_012943.1 3060297 3061103 R truncated CDS; dihydropteroate synthase 2 folP2 complement(3060297..3061103) Mycobacterium tuberculosis KZN 1435 8163806 YP_003032751.1 CDS TBMG_02776 NC_012943.1 3061169 3062962 R activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; long-chain-acyl-CoA synthetase complement(3061169..3062962) Mycobacterium tuberculosis KZN 1435 8163807 YP_003032752.1 CDS TBMG_02777 NC_012943.1 3063012 3063575 R hypothetical protein complement(3063012..3063575) Mycobacterium tuberculosis KZN 1435 8163808 YP_003032753.1 CDS TBMG_04073 NC_012943.1 3063688 3064578 D hypothetical protein 3063688..3064578 Mycobacterium tuberculosis KZN 1435 8163809 YP_003032754.1 CDS TBMG_04074 NC_012943.1 3064605 3065357 D hypothetical protein 3064605..3065357 Mycobacterium tuberculosis KZN 1435 8162055 YP_003032755.1 CDS TBMG_02779 NC_012943.1 3065388 3065972 D hypothetical protein 3065388..3065972 Mycobacterium tuberculosis KZN 1435 8162056 YP_003032756.1 CDS TBMG_02780 NC_012943.1 3065969 3067033 R catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase complement(3065969..3067033) Mycobacterium tuberculosis KZN 1435 8162057 YP_003032757.1 CDS TBMG_02781 NC_012943.1 3067124 3068077 D transferase 3067124..3068077 Mycobacterium tuberculosis KZN 1435 8162058 YP_003032758.1 CDS TBMG_02782 NC_012943.1 3068074 3069351 R membrane transporter complement(3068074..3069351) Mycobacterium tuberculosis KZN 1435 8162059 YP_003032759.1 CDS TBMG_02783 NC_012943.1 3069640 3070935 D transposase 3069640..3070935 Mycobacterium tuberculosis KZN 1435 8162060 YP_003032760.1 CDS TBMG_02784 NC_012943.1 3071003 3071287 R esat-6 like protein esxL complement(3071003..3071287) Mycobacterium tuberculosis KZN 1435 8162061 YP_003032761.1 CDS TBMG_02785 NC_012943.1 3071338 3071634 R esat-6 like protein esxK complement(3071338..3071634) Mycobacterium tuberculosis KZN 1435 8162062 YP_003032762.1 CDS TBMG_02786 NC_012943.1 3071769 3072944 R PPE family protein complement(3071769..3072944) Mycobacterium tuberculosis KZN 1435 8162063 YP_003032763.1 CDS TBMG_02787 NC_012943.1 3072991 3073326 R PE family protein complement(3072991..3073326) Mycobacterium tuberculosis KZN 1435 8162064 YP_003032764.1 CDS TBMG_02788 NC_012943.1 3073780 3075045 D hypothetical protein 3073780..3075045 Mycobacterium tuberculosis KZN 1435 8162065 YP_003032765.1 CDS TBMG_02789 NC_012943.1 3075078 3076499 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(3075078..3076499) Mycobacterium tuberculosis KZN 1435 8162066 YP_003032766.1 CDS TBMG_02790 NC_012943.1 3076539 3077366 R hypothetical protein complement(3076539..3077366) Mycobacterium tuberculosis KZN 1435 8162067 YP_003032767.1 CDS TBMG_02791 NC_012943.1 3077448 3078362 R hypothetical protein complement(3077448..3078362) Mycobacterium tuberculosis KZN 1435 8162068 YP_003032768.1 CDS TBMG_02792 NC_012943.1 3078435 3079313 R hypothetical protein complement(3078435..3079313) Mycobacterium tuberculosis KZN 1435 8162069 YP_003032769.1 CDS sigI NC_012943.1 3079329 3080201 R member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigI complement(3079329..3080201) Mycobacterium tuberculosis KZN 1435 8162070 YP_003032770.1 CDS TBMG_02794 NC_012943.1 3080283 3081272 R proline dehydrogenase complement(3080283..3081272) Mycobacterium tuberculosis KZN 1435 8162071 YP_003032771.1 CDS TBMG_02795 NC_012943.1 3081272 3082903 R pyrroline-5-carboxylate dehydrogenase rocA complement(3081272..3082903) Mycobacterium tuberculosis KZN 1435 8162072 YP_003032772.1 CDS TBMG_02796 NC_012943.1 3083233 3084606 D hypothetical protein 3083233..3084606 Mycobacterium tuberculosis KZN 1435 8162073 YP_003032773.1 CDS TBMG_02797 NC_012943.1 3084783 3086519 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3084783..3086519 Mycobacterium tuberculosis KZN 1435 8162074 YP_003032774.1 CDS TBMG_02798 NC_012943.1 3086684 3087763 D hypothetical protein 3086684..3087763 Mycobacterium tuberculosis KZN 1435 8162075 YP_003032775.1 CDS TBMG_02799 NC_012943.1 3087767 3090775 R transmembrane transporter mmpL10 complement(3087767..3090775) Mycobacterium tuberculosis KZN 1435 8162076 YP_003032776.1 CDS TBMG_02800 NC_012943.1 3090842 3092260 R polyketide synthase complement(3090842..3092260) Mycobacterium tuberculosis KZN 1435 8162077 YP_003032777.1 CDS TBMG_02801 NC_012943.1 3092313 3098618 R polyketide beta-ketoacyl synthase complement(3092313..3098618) Mycobacterium tuberculosis KZN 1435 8162078 YP_003032778.1 CDS TBMG_02802 NC_012943.1 3098997 3101816 D hypothetical protein 3098997..3101816 Mycobacterium tuberculosis KZN 1435 8162079 YP_003032779.1 CDS TBMG_02803 NC_012943.1 3101844 3102932 R catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase complement(3101844..3102932) Mycobacterium tuberculosis KZN 1435 8162080 YP_003032780.1 CDS TBMG_02804 NC_012943.1 3102965 3103291 R ferredoxin fdxC complement(3102965..3103291) Mycobacterium tuberculosis KZN 1435 8162081 YP_003032781.1 CDS TBMG_02805 NC_012943.1 3103504 3104073 D hypothetical protein 3103504..3104073 Mycobacterium tuberculosis KZN 1435 8162082 YP_003032782.1 CDS TBMG_02806 NC_012943.1 3104070 3106094 D NADPH dependent 2,4-dienoyl-CoA reductase fadH 3104070..3106094 Mycobacterium tuberculosis KZN 1435 8162083 YP_003032783.1 CDS TBMG_02807 NC_012943.1 3106295 3106627 D low molecular weight T-cell antigen 3106295..3106627 Mycobacterium tuberculosis KZN 1435 8162084 YP_003032784.1 CDS fbiC NC_012943.1 3106733 3109303 R 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; FO synthase complement(3106733..3109303) Mycobacterium tuberculosis KZN 1435 8162085 YP_003032785.1 CDS TBMG_02809 NC_012943.1 3109553 3110479 D PE family protein 3109553..3110479 Mycobacterium tuberculosis KZN 1435 8162086 YP_003032786.1 CDS TBMG_02810 NC_012943.1 3110487 3110927 R hypothetical protein complement(3110487..3110927) Mycobacterium tuberculosis KZN 1435 8160963 YP_003032787.1 CDS TBMG_02811 NC_012943.1 3111019 3111930 R N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase mshB complement(3111019..3111930) Mycobacterium tuberculosis KZN 1435 8160964 YP_003032788.1 CDS TBMG_02812 NC_012943.1 3112092 3112412 D PE family protein 3112092..3112412 Mycobacterium tuberculosis KZN 1435 8160965 YP_003032789.1 CDS TBMG_02813 NC_012943.1 3112430 3113470 D PPE family protein 3112430..3113470 Mycobacterium tuberculosis KZN 1435 8160966 YP_003032790.1 CDS TBMG_02814 NC_012943.1 3113542 3114147 D transcriptional regulator 3113542..3114147 Mycobacterium tuberculosis KZN 1435 8160967 YP_003032791.1 CDS TBMG_02815 NC_012943.1 3114175 3116082 R hypothetical protein complement(3114175..3116082) Mycobacterium tuberculosis KZN 1435 8160968 YP_003032792.1 CDS TBMG_02816 NC_012943.1 3116180 3118066 R GTP-binding translation elongation factor typA complement(3116180..3118066) Mycobacterium tuberculosis KZN 1435 8160969 YP_003032793.1 CDS TBMG_02817 NC_012943.1 3118088 3118828 R respiratory nitrate reductase subunit gamma narI complement(3118088..3118828) Mycobacterium tuberculosis KZN 1435 8160970 YP_003032794.1 CDS TBMG_02818 NC_012943.1 3118831 3119496 R respiratory nitrate reductase subunit delta narJ complement(3118831..3119496) Mycobacterium tuberculosis KZN 1435 8160971 YP_003032795.1 CDS TBMG_02819 NC_012943.1 3119493 3121169 R respiratory nitrate reductase subunit beta narH complement(3119493..3121169) Mycobacterium tuberculosis KZN 1435 8160972 YP_003032796.1 CDS TBMG_02820 NC_012943.1 3121208 3124906 R respiratory nitrate reductase subunit alpha narG complement(3121208..3124906) Mycobacterium tuberculosis KZN 1435 8160973 YP_003032797.1 CDS TBMG_02821 NC_012943.1 3125214 3125639 R mutator protein mutT complement(3125214..3125639) Mycobacterium tuberculosis KZN 1435 8160974 YP_003032798.1 CDS phhB NC_012943.1 3125666 3125950 D 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 3125666..3125950 Mycobacterium tuberculosis KZN 1435 8160975 YP_003032799.1 CDS pimE NC_012943.1 3125947 3127242 R involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis; mannosyltransferase complement(3125947..3127242) Mycobacterium tuberculosis KZN 1435 8160976 YP_003032800.1 CDS TBMG_02824 NC_012943.1 3127372 3128055 D hypothetical protein 3127372..3128055 Mycobacterium tuberculosis KZN 1435 8160977 YP_003032801.1 CDS TBMG_02825 NC_012943.1 3128135 3129178 D hypothetical protein 3128135..3129178 Mycobacterium tuberculosis KZN 1435 8160978 YP_003032802.1 CDS TBMG_02826 NC_012943.1 3129341 3129928 R hypothetical protein complement(3129341..3129928) Mycobacterium tuberculosis KZN 1435 8160979 YP_003032803.1 CDS TBMG_02827 NC_012943.1 3130362 3130805 R hypothetical protein complement(3130362..3130805) Mycobacterium tuberculosis KZN 1435 8160980 YP_003032804.1 CDS TBMG_02828 NC_012943.1 3130750 3131391 D hypothetical protein 3130750..3131391 Mycobacterium tuberculosis KZN 1435 8160982 YP_003032805.1 CDS TBMG_02829 NC_012943.1 3131388 3132236 D O-methyltransferase omt 3131388..3132236 Mycobacterium tuberculosis KZN 1435 8160981 YP_003032806.1 CDS TBMG_02830 NC_012943.1 3132214 3132579 R transcriptional regulator complement(3132214..3132579) Mycobacterium tuberculosis KZN 1435 8160983 YP_003032807.1 CDS TBMG_02831 NC_012943.1 3132617 3133330 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 3132617..3133330 Mycobacterium tuberculosis KZN 1435 8160984 YP_003032808.1 CDS TBMG_02832 NC_012943.1 3133414 3134277 R transposase complement(3133414..3134277) Mycobacterium tuberculosis KZN 1435 8160985 YP_003032809.1 CDS TBMG_02833 NC_012943.1 3134436 3135935 D hypothetical protein 3134436..3135935 Mycobacterium tuberculosis KZN 1435 8160986 YP_003032810.1 CDS TBMG_02834 NC_012943.1 3136261 3136593 R hypothetical protein complement(3136261..3136593) Mycobacterium tuberculosis KZN 1435 8160987 YP_003032811.1 CDS TBMG_02835 NC_012943.1 3136685 3137335 R hypothetical protein complement(3136685..3137335) Mycobacterium tuberculosis KZN 1435 8160988 YP_003032812.1 CDS TBMG_02836 NC_012943.1 3137468 3138880 R transmembrane transporter mmpL13b complement(3137468..3138880) Mycobacterium tuberculosis KZN 1435 8160989 YP_003032813.1 CDS TBMG_02837 NC_012943.1 3138901 3139986 R transmembrane transporter mmpL13a complement(3138901..3139986) Mycobacterium tuberculosis KZN 1435 8160990 YP_003032814.1 CDS TBMG_04075 NC_012943.1 3140044 3140199 D hypothetical protein 3140044..3140199 Mycobacterium tuberculosis KZN 1435 8160991 YP_003032815.1 CDS TBMG_02838 NC_012943.1 3140327 3141079 R short-chain type dehydrogenase/reductase complement(3140327..3141079) Mycobacterium tuberculosis KZN 1435 8160992 YP_003032816.1 CDS TBMG_02839 NC_012943.1 3141091 3142278 R alpha-methylacyl-CoA racemase complement(3141091..3142278) Mycobacterium tuberculosis KZN 1435 8160993 YP_003032817.1 CDS TBMG_02840 NC_012943.1 3142277 3143083 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3142277..3143083 Mycobacterium tuberculosis KZN 1435 8160995 YP_003032818.1 CDS TBMG_02841 NC_012943.1 3143217 3144032 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3143217..3144032 Mycobacterium tuberculosis KZN 1435 8160994 YP_003032819.1 CDS TBMG_02842 NC_012943.1 3144040 3144888 R hypothetical protein complement(3144040..3144888) Mycobacterium tuberculosis KZN 1435 8160996 YP_003032820.1 CDS TBMG_02843 NC_012943.1 3145192 3145692 D hypothetical protein 3145192..3145692 Mycobacterium tuberculosis KZN 1435 8160997 YP_003032821.1 CDS TBMG_02844 NC_012943.1 3145689 3146705 D oxidoreductase 3145689..3146705 Mycobacterium tuberculosis KZN 1435 8160998 YP_003032822.1 CDS TBMG_02845 NC_012943.1 3146739 3147143 R enoyl-CoA hydratase complement(3146739..3147143) Mycobacterium tuberculosis KZN 1435 8160999 YP_003032823.1 CDS TBMG_02846 NC_012943.1 3147230 3147571 R enoyl-CoA hydratase complement(3147230..3147571) Mycobacterium tuberculosis KZN 1435 8161000 YP_003032824.1 CDS TBMG_02847 NC_012943.1 3147621 3147863 R acetyl-CoA acetyltransferase complement(3147621..3147863) Mycobacterium tuberculosis KZN 1435 8161001 YP_003032825.1 CDS TBMG_02848 NC_012943.1 3147995 3149905 D PPE family protein 3147995..3149905 Mycobacterium tuberculosis KZN 1435 8161002 YP_003032826.1 CDS TBMG_04076 NC_012943.1 3150019 3150255 R hypothetical protein complement(3150019..3150255) Mycobacterium tuberculosis KZN 1435 8161003 YP_003032827.1 CDS TBMG_02849 NC_012943.1 3150801 3153110 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 3150801..3153110 Mycobacterium tuberculosis KZN 1435 8161004 YP_003032828.1 CDS TBMG_02850 NC_012943.1 3153122 3154852 R hypothetical protein complement(3153122..3154852) Mycobacterium tuberculosis KZN 1435 8161005 YP_003032829.1 CDS TBMG_02851 NC_012943.1 3154864 3156045 R catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase complement(3154864..3156045) Mycobacterium tuberculosis KZN 1435 8161006 YP_003032830.1 CDS TBMG_02852 NC_012943.1 3156042 3157622 R hypothetical protein complement(3156042..3157622) Mycobacterium tuberculosis KZN 1435 8161007 YP_003032831.1 CDS TBMG_02853 NC_012943.1 3157643 3159103 D transcriptional regulator 3157643..3159103 Mycobacterium tuberculosis KZN 1435 8161008 YP_003032832.1 CDS TBMG_02854 NC_012943.1 3159205 3160560 D hypothetical protein 3159205..3160560 Mycobacterium tuberculosis KZN 1435 8161009 YP_003032833.1 CDS TBMG_02855 NC_012943.1 3160773 3162245 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 3160773..3162245 Mycobacterium tuberculosis KZN 1435 8161010 YP_003032834.1 CDS TBMG_02856 NC_012943.1 3162242 3162847 D hypothetical protein 3162242..3162847 Mycobacterium tuberculosis KZN 1435 8161011 YP_003032835.1 CDS TBMG_02857 NC_012943.1 3162851 3164095 R hypothetical protein complement(3162851..3164095) Mycobacterium tuberculosis KZN 1435 8161012 YP_003032836.1 CDS TBMG_02858 NC_012943.1 3164100 3165050 R epoxide hydrolase ephC complement(3164100..3165050) Mycobacterium tuberculosis KZN 1435 8161013 YP_003032837.1 CDS TBMG_02859 NC_012943.1 3165125 3166033 D peroxidase bpoB 3165125..3166033 Mycobacterium tuberculosis KZN 1435 8161014 YP_003032838.1 CDS TBMG_02860 NC_012943.1 3166026 3167048 R similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase complement(3166026..3167048) Mycobacterium tuberculosis KZN 1435 8161015 YP_003032839.1 CDS TBMG_02861 NC_012943.1 3167070 3168470 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(3167070..3168470) Mycobacterium tuberculosis KZN 1435 8161016 YP_003032840.1 CDS TBMG_02862 NC_012943.1 3168673 3169167 D hypothetical protein 3168673..3169167 Mycobacterium tuberculosis KZN 1435 8161017 YP_003032841.1 CDS TBMG_02863 NC_012943.1 3169113 3169313 D hypothetical protein 3169113..3169313 Mycobacterium tuberculosis KZN 1435 8161018 YP_003032842.1 CDS TBMG_02864 NC_012943.1 3169346 3170206 D hypothetical protein 3169346..3170206 Mycobacterium tuberculosis KZN 1435 8161019 YP_003032843.1 CDS TBMG_02865 NC_012943.1 3170221 3170544 R hypothetical protein complement(3170221..3170544) Mycobacterium tuberculosis KZN 1435 8161020 YP_003032844.1 CDS TBMG_02866 NC_012943.1 3170787 3171062 D hypothetical protein 3170787..3171062 Mycobacterium tuberculosis KZN 1435 8161021 YP_003032845.1 CDS TBMG_02867 NC_012943.1 3170989 3171174 R hypothetical protein complement(3170989..3171174) Mycobacterium tuberculosis KZN 1435 8161022 YP_003032846.1 CDS TBMG_02868 NC_012943.1 3171292 3171990 R hypothetical protein complement(3171292..3171990) Mycobacterium tuberculosis KZN 1435 8161023 YP_003032847.1 CDS TBMG_02869 NC_012943.1 3172193 3172567 R toxin complement(3172193..3172567) Mycobacterium tuberculosis KZN 1435 8161024 YP_003032848.1 CDS TBMG_02870 NC_012943.1 3172564 3172761 R antitoxin complement(3172564..3172761) Mycobacterium tuberculosis KZN 1435 8161025 YP_003032849.1 CDS TBMG_02871 NC_012943.1 3172849 3173922 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(3172849..3173922) Mycobacterium tuberculosis KZN 1435 8161026 YP_003032850.1 CDS TBMG_02872 NC_012943.1 3173985 3174968 D hypothetical protein 3173985..3174968 Mycobacterium tuberculosis KZN 1435 8161027 YP_003032851.1 CDS ispH NC_012943.1 3174985 3175992 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(3174985..3175992) Mycobacterium tuberculosis KZN 1435 8161028 YP_003032852.1 CDS TBMG_02874 NC_012943.1 3176082 3176720 D hypothetical protein 3176082..3176720 Mycobacterium tuberculosis KZN 1435 8161029 YP_003032853.1 CDS xseA NC_012943.1 3176717 3177964 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 3176717..3177964 Mycobacterium tuberculosis KZN 1435 8161030 YP_003032854.1 CDS TBMG_02876 NC_012943.1 3177954 3178211 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 3177954..3178211 Mycobacterium tuberculosis KZN 1435 8161031 YP_003032855.1 CDS TBMG_02877 NC_012943.1 3178221 3179333 D cholesterol dehydrogenase 3178221..3179333 Mycobacterium tuberculosis KZN 1435 8161032 YP_003032856.1 CDS TBMG_02878 NC_012943.1 3179351 3179761 R para-nitrobenzyl esterase complement(3179351..3179761) Mycobacterium tuberculosis KZN 1435 8161033 YP_003032857.1 CDS TBMG_02879 NC_012943.1 3179715 3180113 R para-nitrobenzyl esterase complement(3179715..3180113) Mycobacterium tuberculosis KZN 1435 8161034 YP_003032858.1 CDS TBMG_02880 NC_012943.1 3180187 3180876 R para-nitrobenzyl esterase complement(3180187..3180876) Mycobacterium tuberculosis KZN 1435 8161035 YP_003032859.1 CDS TBMG_02881 NC_012943.1 3180886 3181206 D antitoxin 3180886..3181206 Mycobacterium tuberculosis KZN 1435 8161036 YP_003032860.1 CDS TBMG_02882 NC_012943.1 3181206 3181517 D toxin 3181206..3181517 Mycobacterium tuberculosis KZN 1435 8161037 YP_003032861.1 CDS TBMG_02883 NC_012943.1 3181629 3182786 D hypothetical protein 3181629..3182786 Mycobacterium tuberculosis KZN 1435 8161038 YP_003032862.1 CDS TBMG_02884 NC_012943.1 3182793 3183494 R hypothetical protein complement(3182793..3183494) Mycobacterium tuberculosis KZN 1435 8161039 YP_003032863.1 CDS glpX NC_012943.1 3183529 3184581 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 3183529..3184581 Mycobacterium tuberculosis KZN 1435 8161040 YP_003032864.1 CDS fumC NC_012943.1 3184612 3186036 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 3184612..3186036 Mycobacterium tuberculosis KZN 1435 8161041 YP_003032865.1 CDS TBMG_02887 NC_012943.1 3186033 3186914 D hypothetical protein 3186033..3186914 Mycobacterium tuberculosis KZN 1435 8161889 YP_003032866.1 CDS TBMG_02888 NC_012943.1 3186917 3187792 R glycosyl hydrolase complement(3186917..3187792) Mycobacterium tuberculosis KZN 1435 8161890 YP_003032867.1 CDS TBMG_02889 NC_012943.1 3187879 3189180 R phosphate starvation-inducible protein phoH2 complement(3187879..3189180) Mycobacterium tuberculosis KZN 1435 8161891 YP_003032868.1 CDS TBMG_02890 NC_012943.1 3189391 3190218 R acyl-ACP desaturase complement(3189391..3190218) Mycobacterium tuberculosis KZN 1435 8161892 YP_003032869.1 CDS glyA NC_012943.1 3190323 3191603 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(3190323..3191603) Mycobacterium tuberculosis KZN 1435 8161893 YP_003032870.1 CDS TBMG_02892 NC_012943.1 3191991 3192929 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3191991..3192929 Mycobacterium tuberculosis KZN 1435 8161894 YP_003032871.1 CDS TBMG_04077 NC_012943.1 3193147 3195627 R PE-PGRS family protein complement(3193147..3195627) Mycobacterium tuberculosis KZN 1435 8161895 YP_003032872.1 CDS TBMG_02895 NC_012943.1 3196042 3196497 R cellulase celA2b complement(3196042..3196497) Mycobacterium tuberculosis KZN 1435 8161896 YP_003032873.1 CDS TBMG_02896 NC_012943.1 3196475 3196579 R cellulase celA2a complement(3196475..3196579) Mycobacterium tuberculosis KZN 1435 8161897 YP_003032874.1 CDS TBMG_04078 NC_012943.1 3196689 3196871 R hypothetical protein complement(3196689..3196871) Mycobacterium tuberculosis KZN 1435 8161898 YP_003032875.1 CDS TBMG_02897 NC_012943.1 3196965 3197270 R PE family protein complement(3196965..3197270) Mycobacterium tuberculosis KZN 1435 8161899 YP_003032876.1 CDS TBMG_02898 NC_012943.1 3197149 3197583 R PE family protein complement(3197149..3197583) Mycobacterium tuberculosis KZN 1435 8161900 YP_003032877.1 CDS TBMG_02899 NC_012943.1 3197736 3198056 R hypothetical protein complement(3197736..3198056) Mycobacterium tuberculosis KZN 1435 8161901 YP_003032878.1 CDS TBMG_02900 NC_012943.1 3198233 3200449 R PE-PGRS family protein complement(3198233..3200449) Mycobacterium tuberculosis KZN 1435 8161902 YP_003032879.1 CDS TBMG_02901 NC_012943.1 3200587 3201375 R short-chain (C15) Z-isoprenyl diphosphate synthase complement(3200587..3201375) Mycobacterium tuberculosis KZN 1435 8161903 YP_003032880.1 CDS TBMG_02902 NC_012943.1 3201486 3202214 D hemolysin 3201486..3202214 Mycobacterium tuberculosis KZN 1435 8161904 YP_003032881.1 CDS TBMG_02903 NC_012943.1 3202313 3204334 R hypothetical protein complement(3202313..3204334) Mycobacterium tuberculosis KZN 1435 8161905 YP_003032882.1 CDS TBMG_02904 NC_012943.1 3204321 3204587 R hypothetical protein complement(3204321..3204587) Mycobacterium tuberculosis KZN 1435 8161906 YP_003032883.1 CDS TBMG_02905 NC_012943.1 3204584 3205450 R mycothiol conjugate amidase mca complement(3204584..3205450) Mycobacterium tuberculosis KZN 1435 8161907 YP_003032884.1 CDS TBMG_02906 NC_012943.1 3205525 3205986 D hypothetical protein 3205525..3205986 Mycobacterium tuberculosis KZN 1435 8161908 YP_003032885.1 CDS greA NC_012943.1 3206172 3206666 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3206172..3206666 Mycobacterium tuberculosis KZN 1435 8161909 YP_003032886.1 CDS TBMG_02908 NC_012943.1 3206737 3207903 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(3206737..3207903) Mycobacterium tuberculosis KZN 1435 8161910 YP_003032887.1 CDS TBMG_02909 NC_012943.1 3207935 3208657 R hypothetical protein complement(3207935..3208657) Mycobacterium tuberculosis KZN 1435 8161911 YP_003032888.1 CDS TBMG_02910 NC_012943.1 3208859 3210253 R cystathionine beta-synthase cbs complement(3208859..3210253) Mycobacterium tuberculosis KZN 1435 8161912 YP_003032889.1 CDS TBMG_02911 NC_012943.1 3210310 3211386 R lipase lipU complement(3210310..3211386) Mycobacterium tuberculosis KZN 1435 8161913 YP_003032890.1 CDS TBMG_02912 NC_012943.1 3211594 3212544 D hypothetical protein 3211594..3212544 Mycobacterium tuberculosis KZN 1435 8161914 YP_003032891.1 CDS TBMG_02913 NC_012943.1 3212597 3213814 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3212597..3213814 Mycobacterium tuberculosis KZN 1435 8161915 YP_003032892.1 CDS TBMG_02914 NC_012943.1 3214241 3214738 R truncated CDS; hypothetical protein complement(3214241..3214738) Mycobacterium tuberculosis KZN 1435 8161916 YP_003032893.1 CDS TBMG_02915 NC_012943.1 3214854 3215690 R hypothetical protein complement(3214854..3215690) Mycobacterium tuberculosis KZN 1435 8161917 YP_003032894.1 CDS TBMG_02916 NC_012943.1 3215877 3216914 D catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 3215877..3216914 Mycobacterium tuberculosis KZN 1435 8161918 YP_003032895.1 CDS TBMG_02917 NC_012943.1 3216926 3217699 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3216926..3217699 Mycobacterium tuberculosis KZN 1435 8161919 YP_003032896.1 CDS TBMG_02918 NC_012943.1 3217696 3219459 D hypothetical protein 3217696..3219459 Mycobacterium tuberculosis KZN 1435 8161920 YP_003032897.1 CDS TBMG_02919 NC_012943.1 3219803 3221212 D PE-PGRS family protein 3219803..3221212 Mycobacterium tuberculosis KZN 1435 8161921 YP_003032898.1 CDS TBMG_04079 NC_012943.1 3221545 3223545 D PE-PGRS family protein 3221545..3223545 Mycobacterium tuberculosis KZN 1435 8161922 YP_003032899.1 CDS TBMG_02920 NC_012943.1 3223573 3223968 R hypothetical protein complement(3223573..3223968) Mycobacterium tuberculosis KZN 1435 8161923 YP_003032900.1 CDS TBMG_02921 NC_012943.1 3223965 3224531 R hypothetical protein complement(3223965..3224531) Mycobacterium tuberculosis KZN 1435 8161924 YP_003032901.1 CDS TBMG_02922 NC_012943.1 3224643 3225062 D hypothetical protein 3224643..3225062 Mycobacterium tuberculosis KZN 1435 8161925 YP_003032902.1 CDS TBMG_02923 NC_012943.1 3225143 3226225 D hypothetical protein 3225143..3226225 Mycobacterium tuberculosis KZN 1435 8161926 YP_003032903.1 CDS TBMG_02924 NC_012943.1 3226226 3227110 R hypothetical protein complement(3226226..3227110) Mycobacterium tuberculosis KZN 1435 8161927 YP_003032904.1 CDS TBMG_02925 NC_012943.1 3227088 3227951 R hypothetical protein complement(3227088..3227951) Mycobacterium tuberculosis KZN 1435 8161928 YP_003032905.1 CDS TBMG_02926 NC_012943.1 3227985 3228458 R hypothetical protein complement(3227985..3228458) Mycobacterium tuberculosis KZN 1435 8161929 YP_003032906.1 CDS TBMG_02927 NC_012943.1 3228511 3229575 R hypothetical protein complement(3228511..3229575) Mycobacterium tuberculosis KZN 1435 8161930 YP_003032907.1 CDS TBMG_02928 NC_012943.1 3229651 3231282 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(3229651..3231282) Mycobacterium tuberculosis KZN 1435 8161931 YP_003032908.1 CDS TBMG_02929 NC_012943.1 3231389 3232621 R hypothetical protein complement(3231389..3232621) Mycobacterium tuberculosis KZN 1435 8161932 YP_003032909.1 CDS TBMG_04080 NC_012943.1 3233150 3233362 D hypothetical protein 3233150..3233362 Mycobacterium tuberculosis KZN 1435 8161933 YP_003032910.1 CDS TBMG_02930 NC_012943.1 3233574 3234338 R hypothetical protein complement(3233574..3234338) Mycobacterium tuberculosis KZN 1435 8161934 YP_003032911.1 CDS TBMG_02931 NC_012943.1 3234593 3234727 R integrase complement(3234593..3234727) Mycobacterium tuberculosis KZN 1435 8161936 YP_003032912.1 CDS TBMG_02932 NC_012943.1 3234724 3235080 R integrase complement(3234724..3235080) Mycobacterium tuberculosis KZN 1435 8161937 YP_003032913.1 CDS TBMG_02933 NC_012943.1 3235062 3235400 R hypothetical protein complement(3235062..3235400) Mycobacterium tuberculosis KZN 1435 8161938 YP_003032914.1 CDS TBMG_04081 NC_012943.1 3235680 3235955 D hypothetical protein 3235680..3235955 Mycobacterium tuberculosis KZN 1435 8161939 YP_003032915.1 CDS TBMG_04082 NC_012943.1 3235854 3236243 R hypothetical protein complement(3235854..3236243) Mycobacterium tuberculosis KZN 1435 8161940 YP_003032916.1 CDS TBMG_02936 NC_012943.1 3236345 3236971 D hypothetical protein 3236345..3236971 Mycobacterium tuberculosis KZN 1435 8161941 YP_003032917.1 CDS TBMG_02937 NC_012943.1 3237266 3238021 D hypothetical protein 3237266..3238021 Mycobacterium tuberculosis KZN 1435 8161942 YP_003032918.1 CDS TBMG_02938 NC_012943.1 3238180 3239088 R oxidoreductase complement(3238180..3239088) Mycobacterium tuberculosis KZN 1435 8161943 YP_003032919.1 CDS TBMG_02939 NC_012943.1 3239134 3239580 R transcriptional repressor complement(3239134..3239580) Mycobacterium tuberculosis KZN 1435 8161944 YP_003032920.1 CDS TBMG_02940 NC_012943.1 3239813 3240928 D hypothetical protein 3239813..3240928 Mycobacterium tuberculosis KZN 1435 8161945 YP_003032921.1 CDS TBMG_02941 NC_012943.1 3241296 3242606 R transposase complement(3241296..3242606) Mycobacterium tuberculosis KZN 1435 8161946 YP_003032922.1 CDS TBMG_02942 NC_012943.1 3242543 3243331 D hypothetical protein 3242543..3243331 Mycobacterium tuberculosis KZN 1435 8161948 YP_003032923.1 CDS TBMG_02943 NC_012943.1 3243413 3244294 R hypothetical protein complement(3243413..3244294) Mycobacterium tuberculosis KZN 1435 8161947 YP_003032924.1 CDS TBMG_02944 NC_012943.1 3244291 3244914 R hypothetical protein complement(3244291..3244914) Mycobacterium tuberculosis KZN 1435 8161949 YP_003032925.1 CDS TBMG_02945 NC_012943.1 3245155 3246186 D hypothetical protein 3245155..3246186 Mycobacterium tuberculosis KZN 1435 8161950 YP_003032926.1 CDS TBMG_04083 NC_012943.1 3246469 3246876 D transposase 3246469..3246876 Mycobacterium tuberculosis KZN 1435 8161951 YP_003032927.1 CDS TBMG_04084 NC_012943.1 3246959 3247396 D transposase 3246959..3247396 Mycobacterium tuberculosis KZN 1435 8161952 YP_003032928.1 CDS TBMG_04085 NC_012943.1 3247532 3247804 D hypothetical protein 3247532..3247804 Mycobacterium tuberculosis KZN 1435 8161953 YP_003032929.1 CDS TBMG_02947 NC_012943.1 3248592 3249419 D PE family protein 3248592..3249419 Mycobacterium tuberculosis KZN 1435 8161954 YP_003032930.1 CDS TBMG_02948 NC_012943.1 3249496 3250671 D PPE family protein 3249496..3250671 Mycobacterium tuberculosis KZN 1435 8161955 YP_003032931.1 CDS TBMG_02949 NC_012943.1 3250817 3251113 D esat-6 like protein esxJ 3250817..3251113 Mycobacterium tuberculosis KZN 1435 8161956 YP_003032932.1 CDS TBMG_02950 NC_012943.1 3251140 3251424 D esat-6 like protein esxI 3251140..3251424 Mycobacterium tuberculosis KZN 1435 8161957 YP_003032933.1 CDS TBMG_02951 NC_012943.1 3251535 3251873 D transposase 3251535..3251873 Mycobacterium tuberculosis KZN 1435 8161958 YP_003032934.1 CDS TBMG_02952 NC_012943.1 3251907 3252593 D transposase 3251907..3252593 Mycobacterium tuberculosis KZN 1435 8161959 YP_003032935.1 CDS TBMG_02953 NC_012943.1 3252556 3253050 D transposase 3252556..3253050 Mycobacterium tuberculosis KZN 1435 8161960 YP_003032936.1 CDS TBMG_02954 NC_012943.1 3253232 3254005 D two component system transcriptional regulator trcR 3253232..3254005 Mycobacterium tuberculosis KZN 1435 8161961 YP_003032937.1 CDS TBMG_04086 NC_012943.1 3254013 3254918 D two component system sensor histidine kinase trcS 3254013..3254918 Mycobacterium tuberculosis KZN 1435 8161962 YP_003032938.1 CDS TBMG_04087 NC_012943.1 3254888 3255541 D two component system sensor histidine kinase trcS 3254888..3255541 Mycobacterium tuberculosis KZN 1435 8161963 YP_003032939.1 CDS TBMG_02956 NC_012943.1 3255545 3256114 R one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(3255545..3256114) Mycobacterium tuberculosis KZN 1435 8161964 YP_003032940.1 CDS TBMG_02957 NC_012943.1 3256114 3258243 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(3256114..3258243) Mycobacterium tuberculosis KZN 1435 8161965 YP_003032941.1 CDS TBMG_02958 NC_012943.1 3258240 3259955 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(3258240..3259955) Mycobacterium tuberculosis KZN 1435 8161966 YP_003032942.1 CDS TBMG_04088 NC_012943.1 3259955 3260047 R hypothetical protein complement(3259955..3260047) Mycobacterium tuberculosis KZN 1435 8161967 YP_003032943.1 CDS TBMG_02959 NC_012943.1 3260281 3262863 D two component system sensor protein kdpD 3260281..3262863 Mycobacterium tuberculosis KZN 1435 8161968 YP_003032944.1 CDS TBMG_02960 NC_012943.1 3262860 3263540 D transcriptional regulator kdpE 3262860..3263540 Mycobacterium tuberculosis KZN 1435 8161969 YP_003032945.1 CDS TBMG_02961 NC_012943.1 3263989 3264948 R hypothetical protein complement(3263989..3264948) Mycobacterium tuberculosis KZN 1435 8161209 YP_003032946.1 CDS TBMG_02962 NC_012943.1 3264939 3265430 R hypothetical protein complement(3264939..3265430) Mycobacterium tuberculosis KZN 1435 8161210 YP_003032947.1 CDS TBMG_02963 NC_012943.1 3265423 3266109 R hypothetical protein complement(3265423..3266109) Mycobacterium tuberculosis KZN 1435 8161211 YP_003032948.1 CDS eno NC_012943.1 3266114 3267403 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3266114..3267403) Mycobacterium tuberculosis KZN 1435 8164080 YP_003032949.1 CDS TBMG_02965 NC_012943.1 3267500 3268231 R hypothetical protein complement(3267500..3268231) Mycobacterium tuberculosis KZN 1435 8164081 YP_003032950.1 CDS TBMG_02966 NC_012943.1 3268319 3269296 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(3268319..3269296) Mycobacterium tuberculosis KZN 1435 8164082 YP_003032951.1 CDS TBMG_02967 NC_012943.1 3269296 3273000 R transcription-repair coupling factor mfd complement(3269296..3273000) Mycobacterium tuberculosis KZN 1435 8164083 YP_003032952.1 CDS TBMG_02968 NC_012943.1 3273059 3273667 R TetR family transcriptional regulator complement(3273059..3273667) Mycobacterium tuberculosis KZN 1435 8164084 YP_003032953.1 CDS glmU NC_012943.1 3273907 3275394 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 3273907..3275394 Mycobacterium tuberculosis KZN 1435 8164086 YP_003032954.1 CDS TBMG_02970 NC_012943.1 3275486 3276466 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 3275486..3276466 Mycobacterium tuberculosis KZN 1435 8164087 YP_003032955.1 CDS TBMG_02971 NC_012943.1 3276502 3277182 D hypothetical protein 3276502..3277182 Mycobacterium tuberculosis KZN 1435 8164088 YP_003032956.1 CDS TBMG_02972 NC_012943.1 3277399 3278046 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 3277399..3278046 Mycobacterium tuberculosis KZN 1435 8164089 YP_003032957.1 CDS TBMG_02973 NC_012943.1 3278059 3278634 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 3278059..3278634 Mycobacterium tuberculosis KZN 1435 8164090 YP_003032958.1 CDS TBMG_02974 NC_012943.1 3278708 3280342 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(3278708..3280342) Mycobacterium tuberculosis KZN 1435 8164091 YP_003032959.1 CDS TBMG_02975 NC_012943.1 3280546 3280839 R hypothetical protein complement(3280546..3280839) Mycobacterium tuberculosis KZN 1435 8164092 YP_003032960.1 CDS TBMG_02976 NC_012943.1 3280856 3281776 R catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(3280856..3281776) Mycobacterium tuberculosis KZN 1435 8164093 YP_003032961.1 CDS ksgA NC_012943.1 3281862 3282833 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(3281862..3282833) Mycobacterium tuberculosis KZN 1435 8164094 YP_003032962.1 CDS TBMG_02978 NC_012943.1 3282788 3283876 R resuscitation-promoting factor rpfB complement(3282788..3283876) Mycobacterium tuberculosis KZN 1435 8164095 YP_003032963.1 CDS TBMG_02979 NC_012943.1 3284084 3284878 R deoxyribonuclease tatD complement(3284084..3284878) Mycobacterium tuberculosis KZN 1435 8164096 YP_003032964.1 CDS TBMG_02980 NC_012943.1 3284964 3286523 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 3284964..3286523 Mycobacterium tuberculosis KZN 1435 8164097 YP_003032965.1 CDS TBMG_02981 NC_012943.1 3286550 3288253 R hypothetical protein complement(3286550..3288253) Mycobacterium tuberculosis KZN 1435 8164098 YP_003032966.1 CDS TBMG_02982 NC_012943.1 3288369 3289745 D catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase component I 3288369..3289745 Mycobacterium tuberculosis KZN 1435 8164099 YP_003032967.1 CDS TBMG_02983 NC_012943.1 3289780 3291078 D hypothetical protein 3289780..3291078 Mycobacterium tuberculosis KZN 1435 8164100 YP_003032968.1 CDS TBMG_02984 NC_012943.1 3291088 3291945 R hypothetical protein complement(3291088..3291945) Mycobacterium tuberculosis KZN 1435 8164101 YP_003032969.1 CDS TBMG_02985 NC_012943.1 3291971 3293539 D hypothetical protein 3291971..3293539 Mycobacterium tuberculosis KZN 1435 8164102 YP_003032970.1 CDS TBMG_02986 NC_012943.1 3293574 3294782 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(3293574..3294782) Mycobacterium tuberculosis KZN 1435 8164103 YP_003032971.1 CDS TBMG_02987 NC_012943.1 3294819 3295436 D hypothetical protein 3294819..3295436 Mycobacterium tuberculosis KZN 1435 8164104 YP_003032972.1 CDS TBMG_02988 NC_012943.1 3295442 3296200 R hypothetical protein complement(3295442..3296200) Mycobacterium tuberculosis KZN 1435 8164105 YP_003032973.1 CDS TBMG_02989 NC_012943.1 3296218 3297219 R hypothetical protein complement(3296218..3297219) Mycobacterium tuberculosis KZN 1435 8164106 YP_003032974.1 CDS TBMG_04089 NC_012943.1 3297261 3297581 D methyltransferase 3297261..3297581 Mycobacterium tuberculosis KZN 1435 8164107 YP_003032975.1 CDS TBMG_02991 NC_012943.1 3297585 3297794 D methyltransferase 3297585..3297794 Mycobacterium tuberculosis KZN 1435 8164108 YP_003032976.1 CDS TBMG_02992 NC_012943.1 3297855 3298106 R hypothetical protein complement(3297855..3298106) Mycobacterium tuberculosis KZN 1435 8164109 YP_003032977.1 CDS TBMG_02993 NC_012943.1 3298507 3299682 R hypothetical protein complement(3298507..3299682) Mycobacterium tuberculosis KZN 1435 8164111 YP_003032978.1 CDS TBMG_02994 NC_012943.1 3299744 3300397 R ribosomal-protein-alanine acetyltransferase rimJ complement(3299744..3300397) Mycobacterium tuberculosis KZN 1435 8164112 YP_003032979.1 CDS TBMG_02995 NC_012943.1 3300418 3301698 R molybdopterin biosynthesis protein moeA1 complement(3300418..3301698) Mycobacterium tuberculosis KZN 1435 8164113 YP_003032980.1 CDS TBMG_02996 NC_012943.1 3301775 3302695 R UTP-glucose-1-phosphate uridylyltransferase complement(3301775..3302695) Mycobacterium tuberculosis KZN 1435 8164114 YP_003032981.1 CDS TBMG_02997 NC_012943.1 3302718 3303389 D hypothetical protein 3302718..3303389 Mycobacterium tuberculosis KZN 1435 8164115 YP_003032982.1 CDS TBMG_02998 NC_012943.1 3303442 3303795 D hypothetical protein 3303442..3303795 Mycobacterium tuberculosis KZN 1435 8164116 YP_003032983.1 CDS TBMG_02999 NC_012943.1 3303868 3304524 D hypothetical protein 3303868..3304524 Mycobacterium tuberculosis KZN 1435 8164117 YP_003032984.1 CDS TBMG_03000 NC_012943.1 3304585 3305562 D polyprenyl synthetase 3304585..3305562 Mycobacterium tuberculosis KZN 1435 8164118 YP_003032985.1 CDS TBMG_03001 NC_012943.1 3305691 3306851 R hypothetical protein complement(3305691..3306851) Mycobacterium tuberculosis KZN 1435 8164119 YP_003032986.1 CDS TBMG_03002 NC_012943.1 3306858 3309425 R hypothetical protein complement(3306858..3309425) Mycobacterium tuberculosis KZN 1435 8164120 YP_003032987.1 CDS TBMG_03003 NC_012943.1 3309418 3310164 R adhesion component transport ATP-binding protein ABC transporter complement(3309418..3310164) Mycobacterium tuberculosis KZN 1435 8164121 YP_003032988.1 CDS mscL NC_012943.1 3310487 3310942 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3310487..3310942 Mycobacterium tuberculosis KZN 1435 8164122 YP_003032989.1 CDS TBMG_03005 NC_012943.1 3310962 3311507 R pterin-4-alpha-carbinolamine dehydratase complement(3310962..3311507) Mycobacterium tuberculosis KZN 1435 8164123 YP_003032990.1 CDS TBMG_03006 NC_012943.1 3311507 3312901 R serine protease pepD complement(3311507..3312901) Mycobacterium tuberculosis KZN 1435 8164124 YP_003032991.1 CDS TBMG_03007 NC_012943.1 3312945 3314459 R two component system sensor kinase mprB complement(3312945..3314459) Mycobacterium tuberculosis KZN 1435 8164125 YP_003032992.1 CDS TBMG_03008 NC_012943.1 3314459 3315151 R persistence regulator MprA complement(3314459..3315151) Mycobacterium tuberculosis KZN 1435 8164126 YP_003032993.1 CDS TBMG_03009 NC_012943.1 3315516 3316889 D PE-PGRS family protein 3315516..3316889 Mycobacterium tuberculosis KZN 1435 8164127 YP_003032994.2 CDS TBMG_03010 NC_012943.1 3316908 3317081 R 50S ribosomal protein L32 complement(3316908..3317081) Mycobacterium tuberculosis KZN 1435 8164128 YP_003032995.1 CDS TBMG_03011 NC_012943.1 3317611 3318618 D PE-PGRS family protein 3317611..3318618 Mycobacterium tuberculosis KZN 1435 8164129 YP_003032996.1 CDS TBMG_04090 NC_012943.1 3318835 3321636 R PE-PGRS family protein complement(3318835..3321636) Mycobacterium tuberculosis KZN 1435 8164130 YP_003032997.1 CDS TBMG_03012 NC_012943.1 3321804 3323486 D hypothetical protein 3321804..3323486 Mycobacterium tuberculosis KZN 1435 8164131 YP_003032998.1 CDS TBMG_03013 NC_012943.1 3323483 3324631 D acyl-CoA dehydrogenase 3323483..3324631 Mycobacterium tuberculosis KZN 1435 8164132 YP_003032999.1 CDS TBMG_03014 NC_012943.1 3324628 3326223 D acetyl-/propionyl-CoA carboxylase beta subunit accD2 3324628..3326223 Mycobacterium tuberculosis KZN 1435 8164133 YP_003033000.1 CDS TBMG_03015 NC_012943.1 3326229 3328232 D acetyl-/propionyl-CoA carboxylase alpha subunit accA2 3326229..3328232 Mycobacterium tuberculosis KZN 1435 8164134 YP_003033001.1 CDS TBMG_03016 NC_012943.1 3328229 3329395 D acyl-CoA dehydrogenase 3328229..3329395 Mycobacterium tuberculosis KZN 1435 8164135 YP_003033002.1 CDS TBMG_03017 NC_012943.1 3329395 3330204 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3329395..3330204 Mycobacterium tuberculosis KZN 1435 8164136 YP_003033003.1 CDS TBMG_03018 NC_012943.1 3330295 3330927 R hypothetical protein complement(3330295..3330927) Mycobacterium tuberculosis KZN 1435 8164137 YP_003033004.1 CDS TBMG_03019 NC_012943.1 3330924 3333302 R metal cation transporting P-type ATPase ctpV complement(3330924..3333302) Mycobacterium tuberculosis KZN 1435 8164138 YP_003033005.1 CDS TBMG_03020 NC_012943.1 3333292 3333588 R hypothetical protein complement(3333292..3333588) Mycobacterium tuberculosis KZN 1435 8164139 YP_003033006.1 CDS TBMG_03021 NC_012943.1 3333645 3334004 R hypothetical protein complement(3333645..3334004) Mycobacterium tuberculosis KZN 1435 8164140 YP_003033007.1 CDS TBMG_03022 NC_012943.1 3334054 3334746 D hypothetical protein 3334054..3334746 Mycobacterium tuberculosis KZN 1435 8164141 YP_003033008.1 CDS TBMG_03023 NC_012943.1 3334782 3335201 D hypothetical protein 3334782..3335201 Mycobacterium tuberculosis KZN 1435 8164142 YP_003033009.1 CDS TBMG_03024 NC_012943.1 3335301 3335783 D hypothetical protein 3335301..3335783 Mycobacterium tuberculosis KZN 1435 8164143 YP_003033010.1 CDS TBMG_03025 NC_012943.1 3335720 3336682 D hypothetical protein 3335720..3336682 Mycobacterium tuberculosis KZN 1435 8164144 YP_003033011.1 CDS TBMG_03026 NC_012943.1 3336865 3337539 D hypothetical protein 3336865..3337539 Mycobacterium tuberculosis KZN 1435 8164145 YP_003033012.1 CDS TBMG_03027 NC_012943.1 3337558 3337905 R hypothetical protein complement(3337558..3337905) Mycobacterium tuberculosis KZN 1435 8164146 YP_003033013.1 CDS TBMG_03028 NC_012943.1 3338051 3338434 R toxin complement(3338051..3338434) Mycobacterium tuberculosis KZN 1435 8164147 YP_003033014.1 CDS TBMG_03029 NC_012943.1 3338431 3338652 R antitoxin complement(3338431..3338652) Mycobacterium tuberculosis KZN 1435 8164148 YP_003033015.1 CDS TBMG_03030 NC_012943.1 3338706 3340724 R hypothetical protein complement(3338706..3340724) Mycobacterium tuberculosis KZN 1435 8164149 YP_003033016.1 CDS TBMG_03031 NC_012943.1 3340717 3342096 R magnesium chelatase complement(3340717..3342096) Mycobacterium tuberculosis KZN 1435 8164150 YP_003033017.1 CDS purH NC_012943.1 3342203 3343774 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(3342203..3343774) Mycobacterium tuberculosis KZN 1435 8164151 YP_003033018.1 CDS purN NC_012943.1 3343771 3344418 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(3343771..3344418) Mycobacterium tuberculosis KZN 1435 8164152 YP_003033019.1 CDS TBMG_03034 NC_012943.1 3344534 3345901 R hypothetical protein complement(3344534..3345901) Mycobacterium tuberculosis KZN 1435 8164153 YP_003033020.1 CDS TBMG_03035 NC_012943.1 3345941 3346852 R hypothetical protein complement(3345941..3346852) Mycobacterium tuberculosis KZN 1435 8164154 YP_003033021.1 CDS TBMG_03036 NC_012943.1 3346993 3347865 D oxidoreductase 3346993..3347865 Mycobacterium tuberculosis KZN 1435 8164155 YP_003033022.1 CDS TBMG_04091 NC_012943.1 3347928 3348839 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(3347928..3348839) Mycobacterium tuberculosis KZN 1435 8164156 YP_003033023.1 CDS sucC NC_012943.1 3348852 3350015 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(3348852..3350015) Mycobacterium tuberculosis KZN 1435 8164157 YP_003033024.1 CDS TBMG_03038 NC_012943.1 3350758 3351321 D truncated CDS; hypothetical protein 3350758..3351321 Mycobacterium tuberculosis KZN 1435 8164158 YP_003033025.1 CDS TBMG_03039 NC_012943.1 3351402 3353717 R ATP-dependent DNA helicase II uvrD1 complement(3351402..3353717) Mycobacterium tuberculosis KZN 1435 8160822 YP_003033026.1 CDS TBMG_03040 NC_012943.1 3354014 3354331 D hypothetical protein 3354014..3354331 Mycobacterium tuberculosis KZN 1435 8160823 YP_003033027.1 CDS TBMG_03041 NC_012943.1 3354447 3354677 D mycolyl transferase 3354447..3354677 Mycobacterium tuberculosis KZN 1435 8160824 YP_003033028.1 CDS TBMG_03042 NC_012943.1 3354907 3355191 D hypothetical protein 3354907..3355191 Mycobacterium tuberculosis KZN 1435 8163810 YP_003033029.1 CDS pgi NC_012943.1 3355292 3356953 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 3355292..3356953 Mycobacterium tuberculosis KZN 1435 8161403 YP_003033030.1 CDS TBMG_03044 NC_012943.1 3356969 3357730 R short chain dehydrogenase complement(3356969..3357730) Mycobacterium tuberculosis KZN 1435 8161404 YP_003033031.1 CDS TBMG_03045 NC_012943.1 3357736 3358236 R formamidopyrimidine-DNA glycosylase complement(3357736..3358236) Mycobacterium tuberculosis KZN 1435 8161405 YP_003033032.1 CDS TBMG_03046 NC_012943.1 3358339 3359280 D monooxygenase 3358339..3359280 Mycobacterium tuberculosis KZN 1435 8161406 YP_003033033.1 CDS TBMG_03048 NC_012943.1 3359659 3360432 D hypothetical protein 3359659..3360432 Mycobacterium tuberculosis KZN 1435 8161407 YP_003033034.1 CDS TBMG_03049 NC_012943.1 3360517 3361383 D oxidoreductase 3360517..3361383 Mycobacterium tuberculosis KZN 1435 8161408 YP_003033035.1 CDS TBMG_03050 NC_012943.1 3361630 3363564 R bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase complement(3361630..3363564) Mycobacterium tuberculosis KZN 1435 8161409 YP_003033036.1 CDS TBMG_03051 NC_012943.1 3363561 3365840 R catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; ATP-dependent DNA ligase complement(3363561..3365840) Mycobacterium tuberculosis KZN 1435 8161410 YP_003033037.1 CDS TBMG_03052 NC_012943.1 3365956 3366777 D Ku protein 3365956..3366777 Mycobacterium tuberculosis KZN 1435 8161411 YP_003033038.1 CDS TBMG_03053 NC_012943.1 3366754 3367659 R phosphate ABC transporter permease complement(3366754..3367659) Mycobacterium tuberculosis KZN 1435 8161412 YP_003033039.1 CDS TBMG_03054 NC_012943.1 3367661 3368677 R phosphate ABC transporter permease complement(3367661..3368677) Mycobacterium tuberculosis KZN 1435 8161413 YP_003033040.1 CDS TBMG_03055 NC_012943.1 3368737 3369861 R periplasmic phosphate-binding lipoprotein pstS1 complement(3368737..3369861) Mycobacterium tuberculosis KZN 1435 8161414 YP_003033041.1 CDS TBMG_03056 NC_012943.1 3369882 3370712 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein complement(3369882..3370712) Mycobacterium tuberculosis KZN 1435 8161415 YP_003033042.1 CDS TBMG_03057 NC_012943.1 3370928 3372040 D periplasmic phosphate-binding lipoprotein pstS2 3370928..3372040 Mycobacterium tuberculosis KZN 1435 8161416 YP_003033043.1 CDS TBMG_03058 NC_012943.1 3372062 3374056 D Ser/Thr protein kinase 3372062..3374056 Mycobacterium tuberculosis KZN 1435 8161417 YP_003033044.1 CDS TBMG_03059 NC_012943.1 3374063 3374977 R phosphate ABC transporter permease complement(3374063..3374977) Mycobacterium tuberculosis KZN 1435 8161418 YP_003033045.1 CDS TBMG_03060 NC_012943.1 3374974 3375948 R phosphate ABC transporter permease complement(3374974..3375948) Mycobacterium tuberculosis KZN 1435 8161419 YP_003033046.1 CDS TBMG_03061 NC_012943.1 3375961 3377073 R periplasmic phosphate-binding lipoprotein pstS3 complement(3375961..3377073) Mycobacterium tuberculosis KZN 1435 8161420 YP_003033047.1 CDS TBMG_03062 NC_012943.1 3377345 3378136 D short chain dehydrogenase 3377345..3378136 Mycobacterium tuberculosis KZN 1435 8161421 YP_003033048.1 CDS TBMG_03063 NC_012943.1 3378190 3379266 D hypothetical protein 3378190..3379266 Mycobacterium tuberculosis KZN 1435 8161422 YP_003033049.1 CDS TBMG_03064 NC_012943.1 3379343 3380080 D hypothetical protein 3379343..3380080 Mycobacterium tuberculosis KZN 1435 8161423 YP_003033050.1 CDS TBMG_03065 NC_012943.1 3380611 3381399 D hypothetical protein 3380611..3381399 Mycobacterium tuberculosis KZN 1435 8161424 YP_003033051.1 CDS TBMG_03066 NC_012943.1 3381400 3382464 D hypothetical protein 3381400..3382464 Mycobacterium tuberculosis KZN 1435 8161425 YP_003033052.1 CDS TBMG_03067 NC_012943.1 3382640 3384292 R transposase complement(3382640..3384292) Mycobacterium tuberculosis KZN 1435 8161426 YP_003033053.1 CDS TBMG_03068 NC_012943.1 3384292 3384873 R resolvase complement(3384292..3384873) Mycobacterium tuberculosis KZN 1435 8161427 YP_003033054.1 CDS TBMG_03069 NC_012943.1 3385161 3386480 D transposase 3385161..3386480 Mycobacterium tuberculosis KZN 1435 8161428 YP_003033055.1 CDS TBMG_03070 NC_012943.1 3386793 3387293 R hypothetical protein complement(3386793..3387293) Mycobacterium tuberculosis KZN 1435 8161430 YP_003033056.1 CDS TBMG_03071 NC_012943.1 3387290 3387766 R hypothetical protein complement(3387290..3387766) Mycobacterium tuberculosis KZN 1435 8161431 YP_003033057.1 CDS TBMG_04092 NC_012943.1 3387855 3388112 R hypothetical protein complement(3387855..3388112) Mycobacterium tuberculosis KZN 1435 8161432 YP_003033058.1 CDS TBMG_03072 NC_012943.1 3388109 3389890 R hypothetical protein complement(3388109..3389890) Mycobacterium tuberculosis KZN 1435 8161433 YP_003033059.1 CDS TBMG_03073 NC_012943.1 3390334 3390633 D PE family protein 3390334..3390633 Mycobacterium tuberculosis KZN 1435 8161434 YP_003033060.1 CDS TBMG_03074 NC_012943.1 3390648 3391919 D PPE family protein 3390648..3391919 Mycobacterium tuberculosis KZN 1435 8161435 YP_003033061.1 CDS TBMG_03075 NC_012943.1 3392012 3393250 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3392012..3393250 Mycobacterium tuberculosis KZN 1435 8161436 YP_003033062.1 CDS TBMG_03076 NC_012943.1 3393252 3394760 D dioxygenase 3393252..3394760 Mycobacterium tuberculosis KZN 1435 8161437 YP_003033063.1 CDS TBMG_04093 NC_012943.1 3394762 3395157 D hypothetical protein 3394762..3395157 Mycobacterium tuberculosis KZN 1435 8161438 YP_003033064.1 CDS TBMG_03077 NC_012943.1 3395292 3395765 R hypothetical protein complement(3395292..3395765) Mycobacterium tuberculosis KZN 1435 8161439 YP_003033065.1 CDS TBMG_03078 NC_012943.1 3395806 3396579 R hypothetical protein complement(3395806..3396579) Mycobacterium tuberculosis KZN 1435 8161440 YP_003033066.1 CDS TBMG_03079 NC_012943.1 3396677 3397111 R hypothetical protein complement(3396677..3397111) Mycobacterium tuberculosis KZN 1435 8161441 YP_003033067.1 CDS TBMG_03080 NC_012943.1 3397117 3397296 R hypothetical protein complement(3397117..3397296) Mycobacterium tuberculosis KZN 1435 8161442 YP_003033068.1 CDS TBMG_04094 NC_012943.1 3397422 3397580 R hypothetical protein complement(3397422..3397580) Mycobacterium tuberculosis KZN 1435 8161443 YP_003033069.1 CDS TBMG_03081 NC_012943.1 3397853 3400246 R metal cation transporting P-type ATPase ctpE complement(3397853..3400246) Mycobacterium tuberculosis KZN 1435 8161444 YP_003033070.1 CDS TBMG_03082 NC_012943.1 3400243 3401931 R hypothetical protein complement(3400243..3401931) Mycobacterium tuberculosis KZN 1435 8161445 YP_003033071.1 CDS TBMG_03083 NC_012943.1 3401916 3403034 R hypothetical protein complement(3401916..3403034) Mycobacterium tuberculosis KZN 1435 8161446 YP_003033072.1 CDS TBMG_03084 NC_012943.1 3403040 3403771 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(3403040..3403771) Mycobacterium tuberculosis KZN 1435 8161447 YP_003033073.1 CDS TBMG_03085 NC_012943.1 3403798 3405285 D acetyl-CoA carboxylase carboxyl transferase beta subunit accD3 3403798..3405285 Mycobacterium tuberculosis KZN 1435 8161448 YP_003033074.1 CDS TBMG_03086 NC_012943.1 3405416 3406126 D two component system transcriptional regulator prrA 3405416..3406126 Mycobacterium tuberculosis KZN 1435 8161449 YP_003033075.1 CDS TBMG_03087 NC_012943.1 3406137 3407477 D two component system sensor histidine kinase prrB 3406137..3407477 Mycobacterium tuberculosis KZN 1435 8161450 YP_003033076.1 CDS TBMG_03088 NC_012943.1 3407494 3408021 R hypothetical protein complement(3407494..3408021) Mycobacterium tuberculosis KZN 1435 8161451 YP_003033077.1 CDS TBMG_03089 NC_012943.1 3408186 3409166 R hypothetical protein complement(3408186..3409166) Mycobacterium tuberculosis KZN 1435 8161452 YP_003033078.1 CDS TBMG_03090 NC_012943.1 3409274 3409537 D hypothetical protein 3409274..3409537 Mycobacterium tuberculosis KZN 1435 8161453 YP_003033079.1 CDS TBMG_03091 NC_012943.1 3409563 3411170 D oxidoreductase 3409563..3411170 Mycobacterium tuberculosis KZN 1435 8161454 YP_003033080.1 CDS gltA NC_012943.1 3411211 3412506 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(3411211..3412506) Mycobacterium tuberculosis KZN 1435 8161455 YP_003033081.1 CDS TBMG_03093 NC_012943.1 3412679 3414196 R hypothetical protein complement(3412679..3414196) Mycobacterium tuberculosis KZN 1435 8161456 YP_003033082.1 CDS TBMG_03094 NC_012943.1 3414273 3415454 R transcriptional regulator, luxR-family complement(3414273..3415454) Mycobacterium tuberculosis KZN 1435 8161457 YP_003033083.1 CDS TBMG_03095 NC_012943.1 3415683 3416660 D hypothetical protein 3415683..3416660 Mycobacterium tuberculosis KZN 1435 8161458 YP_003033084.1 CDS TBMG_04095 NC_012943.1 3416638 3416916 R monooxygenase complement(3416638..3416916) Mycobacterium tuberculosis KZN 1435 8161459 YP_003033085.1 CDS TBMG_04096 NC_012943.1 3416924 3418126 R monooxygenase complement(3416924..3418126) Mycobacterium tuberculosis KZN 1435 8161460 YP_003033086.1 CDS TBMG_03097 NC_012943.1 3418524 3419381 D transcriptional regulator 3418524..3419381 Mycobacterium tuberculosis KZN 1435 8161461 YP_003033087.1 CDS TBMG_03098 NC_012943.1 3419383 3422031 D transcriptional regulator, luxR-family 3419383..3422031 Mycobacterium tuberculosis KZN 1435 8161462 YP_003033088.1 CDS TBMG_03099 NC_012943.1 3422118 3423239 D forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; citrate synthase 2 3422118..3423239 Mycobacterium tuberculosis KZN 1435 8161463 YP_003033089.1 CDS TBMG_03100 NC_012943.1 3423274 3424797 R hypothetical protein complement(3423274..3424797) Mycobacterium tuberculosis KZN 1435 8161464 YP_003033090.1 CDS TBMG_03101 NC_012943.1 3425156 3425305 R hypothetical protein complement(3425156..3425305) Mycobacterium tuberculosis KZN 1435 8161465 YP_003033091.1 CDS TBMG_03102 NC_012943.1 3425444 3425710 R hypothetical protein complement(3425444..3425710) Mycobacterium tuberculosis KZN 1435 8161466 YP_003033092.1 CDS TBMG_03103 NC_012943.1 3425954 3426466 D hypothetical protein 3425954..3426466 Mycobacterium tuberculosis KZN 1435 8161467 YP_003033093.1 CDS TBMG_03104 NC_012943.1 3426449 3428176 R NADPH:adrenodoxin oxidoreductase fprB complement(3426449..3428176) Mycobacterium tuberculosis KZN 1435 8161468 YP_003033094.1 CDS TBMG_03105 NC_012943.1 3428195 3429217 R hypothetical protein complement(3428195..3429217) Mycobacterium tuberculosis KZN 1435 8161469 YP_003033095.1 CDS TBMG_03106 NC_012943.1 3429425 3430555 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 3429425..3430555 Mycobacterium tuberculosis KZN 1435 8161470 YP_003033096.1 CDS TBMG_03107 NC_012943.1 3430712 3431473 D hypothetical protein 3430712..3431473 Mycobacterium tuberculosis KZN 1435 8161471 YP_003033097.1 CDS TBMG_03108 NC_012943.1 3431470 3431754 R hypothetical protein complement(3431470..3431754) Mycobacterium tuberculosis KZN 1435 8161472 YP_003033098.1 CDS TBMG_03109 NC_012943.1 3431751 3432617 R rRNA methyltransferase complement(3431751..3432617) Mycobacterium tuberculosis KZN 1435 8161473 YP_003033099.1 CDS TBMG_03110 NC_012943.1 3432614 3433045 R transcriptional regulator, marR-family complement(3432614..3433045) Mycobacterium tuberculosis KZN 1435 8161474 YP_003033100.1 CDS TBMG_03111 NC_012943.1 3433223 3433498 D hypothetical protein 3433223..3433498 Mycobacterium tuberculosis KZN 1435 8161475 YP_003033101.1 CDS TBMG_03112 NC_012943.1 3433844 3435121 D PPE family protein 3433844..3435121 Mycobacterium tuberculosis KZN 1435 8161476 YP_003033102.1 CDS TBMG_03113 NC_012943.1 3435116 3435904 R hypothetical protein complement(3435116..3435904) Mycobacterium tuberculosis KZN 1435 8161477 YP_003033103.1 CDS TBMG_03114 NC_012943.1 3436009 3437688 D hypothetical protein 3436009..3437688 Mycobacterium tuberculosis KZN 1435 8161478 YP_003033104.1 CDS TBMG_03115 NC_012943.1 3437685 3438173 D hypothetical protein 3437685..3438173 Mycobacterium tuberculosis KZN 1435 8161479 YP_003033105.1 CDS TBMG_03116 NC_012943.1 3438273 3439433 D hypothetical protein 3438273..3439433 Mycobacterium tuberculosis KZN 1435 8161480 YP_003033106.1 CDS TBMG_03117 NC_012943.1 3439522 3441474 R acyl-CoA dehydrogenase complement(3439522..3441474) Mycobacterium tuberculosis KZN 1435 8161481 YP_003033107.1 CDS TBMG_03118 NC_012943.1 3441735 3443564 D hypothetical protein 3441735..3443564 Mycobacterium tuberculosis KZN 1435 8161482 YP_003033108.1 CDS TBMG_03119 NC_012943.1 3443683 3444099 R cold shock protein B cspB complement(3443683..3444099) Mycobacterium tuberculosis KZN 1435 8161483 YP_003033109.1 CDS TBMG_03120 NC_012943.1 3444255 3444644 D hypothetical protein 3444255..3444644 Mycobacterium tuberculosis KZN 1435 8160577 YP_003033110.1 CDS moaA NC_012943.1 3444641 3445723 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 3444641..3445723 Mycobacterium tuberculosis KZN 1435 8160741 YP_003033111.1 CDS TBMG_03122 NC_012943.1 3445727 3446005 D molybdenum cofactor biosynthesis protein D 2 moaD2 3445727..3446005 Mycobacterium tuberculosis KZN 1435 8160742 YP_003033112.1 CDS TBMG_03123 NC_012943.1 3446453 3447676 D resuscitation-promoting factor rpfA 3446453..3447676 Mycobacterium tuberculosis KZN 1435 8160743 YP_003033113.1 CDS TBMG_03124 NC_012943.1 3447694 3448119 R molybdenum cofactor biosynthesis protein E2 moaE2 complement(3447694..3448119) Mycobacterium tuberculosis KZN 1435 8160744 YP_003033114.1 CDS TBMG_03125 NC_012943.1 3448116 3448598 R molybdopterin biosynthesis protein mog complement(3448116..3448598) Mycobacterium tuberculosis KZN 1435 8160745 YP_003033115.1 CDS moaC NC_012943.1 3448595 3449098 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(3448595..3449098) Mycobacterium tuberculosis KZN 1435 8160746 YP_003033116.1 CDS TBMG_03127 NC_012943.1 3449108 3449389 R hypothetical protein complement(3449108..3449389) Mycobacterium tuberculosis KZN 1435 8160747 YP_003033117.1 CDS TBMG_03128 NC_012943.1 3449376 3450776 D truncated CDS; hypothetical protein 3449376..3450776 Mycobacterium tuberculosis KZN 1435 8160749 YP_003033118.1 CDS TBMG_03129 NC_012943.1 3451889 3453517 D DNA helicase ercc3 3451889..3453517 Mycobacterium tuberculosis KZN 1435 8160748 YP_003033119.1 CDS TBMG_03130 NC_012943.1 3453585 3455747 R fatty-acid oxidation protein fadB complement(3453585..3455747) Mycobacterium tuberculosis KZN 1435 8160750 YP_003033120.1 CDS TBMG_03131 NC_012943.1 3455752 3456963 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(3455752..3456963) Mycobacterium tuberculosis KZN 1435 8160751 YP_003033121.1 CDS TBMG_03132 NC_012943.1 3457120 3458313 D aminotransferase 3457120..3458313 Mycobacterium tuberculosis KZN 1435 8160752 YP_003033122.1 CDS TBMG_03133 NC_012943.1 3458310 3458783 R hypothetical protein complement(3458310..3458783) Mycobacterium tuberculosis KZN 1435 8160753 YP_003033123.1 CDS TBMG_03134 NC_012943.1 3458811 3459245 R hypothetical protein complement(3458811..3459245) Mycobacterium tuberculosis KZN 1435 8160754 YP_003033124.1 CDS TBMG_03135 NC_012943.1 3459329 3460408 R fatty-acid-CoA racemase far complement(3459329..3460408) Mycobacterium tuberculosis KZN 1435 8160755 YP_003033125.1 CDS TBMG_03136 NC_012943.1 3460414 3460857 R hypothetical protein complement(3460414..3460857) Mycobacterium tuberculosis KZN 1435 8160756 YP_003033126.1 CDS TBMG_03137 NC_012943.1 3460922 3462604 D pyruvate or indole-3-pyruvate decarboxylase pdc 3460922..3462604 Mycobacterium tuberculosis KZN 1435 8160757 YP_003033127.1 CDS TBMG_03138 NC_012943.1 3462645 3463481 R fatty-acid-CoA ligase fadD16 complement(3462645..3463481) Mycobacterium tuberculosis KZN 1435 8160758 YP_003033128.1 CDS TBMG_03139 NC_012943.1 3463572 3464399 D short chain dehydrogenase 3463572..3464399 Mycobacterium tuberculosis KZN 1435 8160759 YP_003033129.1 CDS TBMG_03140 NC_012943.1 3464396 3464728 R transposase complement(3464396..3464728) Mycobacterium tuberculosis KZN 1435 8160760 YP_003033130.1 CDS TBMG_03141 NC_012943.1 3464725 3465984 R membrane transporter complement(3464725..3465984) Mycobacterium tuberculosis KZN 1435 8160761 YP_003033131.1 CDS TBMG_03142 NC_012943.1 3465984 3467102 R cysteine synthase A cysK2 complement(3465984..3467102) Mycobacterium tuberculosis KZN 1435 8160762 YP_003033132.1 CDS TBMG_03143 NC_012943.1 3467305 3467721 R hypothetical protein complement(3467305..3467721) Mycobacterium tuberculosis KZN 1435 8160763 YP_003033133.1 CDS TBMG_03144 NC_012943.1 3467846 3469360 D oxidase 3467846..3469360 Mycobacterium tuberculosis KZN 1435 8160764 YP_003033134.1 CDS TBMG_03145 NC_012943.1 3469573 3470850 R two component system sensor kinase complement(3469573..3470850) Mycobacterium tuberculosis KZN 1435 8160765 YP_003033135.1 CDS TBMG_03146 NC_012943.1 3470934 3471584 D nitrate/nitrite response transcriptional regulator narL 3470934..3471584 Mycobacterium tuberculosis KZN 1435 8160766 YP_003033136.1 CDS TBMG_03147 NC_012943.1 3471648 3472652 R dehydrogenase complement(3471648..3472652) Mycobacterium tuberculosis KZN 1435 8160767 YP_003033137.1 CDS TBMG_03148 NC_012943.1 3472636 3473964 R hypothetical protein complement(3472636..3473964) Mycobacterium tuberculosis KZN 1435 8160768 YP_003033138.1 CDS TBMG_03149 NC_012943.1 3474205 3474447 R hypothetical protein complement(3474205..3474447) Mycobacterium tuberculosis KZN 1435 8160769 YP_003033139.1 CDS TBMG_03150 NC_012943.1 3474723 3475583 D proline iminopeptidase pip 3474723..3475583 Mycobacterium tuberculosis KZN 1435 8160770 YP_003033140.1 CDS TBMG_03151 NC_012943.1 3475651 3476463 R hypothetical protein complement(3475651..3476463) Mycobacterium tuberculosis KZN 1435 8160771 YP_003033141.1 CDS TBMG_03152 NC_012943.1 3476550 3477320 R hypothetical protein complement(3476550..3477320) Mycobacterium tuberculosis KZN 1435 8160772 YP_003033142.1 CDS TBMG_03153 NC_012943.1 3478009 3479037 D hypothetical protein 3478009..3479037 Mycobacterium tuberculosis KZN 1435 8160773 YP_003033143.1 CDS TBMG_03154 NC_012943.1 3479015 3479761 D hypothetical protein 3479015..3479761 Mycobacterium tuberculosis KZN 1435 8160774 YP_003033144.1 CDS TBMG_03155 NC_012943.1 3479890 3480216 D transposase 3479890..3480216 Mycobacterium tuberculosis KZN 1435 8160775 YP_003033145.1 CDS TBMG_03156 NC_012943.1 3480267 3481151 D transposase 3480267..3481151 Mycobacterium tuberculosis KZN 1435 8160776 YP_003033146.1 CDS TBMG_03157 NC_012943.1 3481254 3481565 D hydrolase 3481254..3481565 Mycobacterium tuberculosis KZN 1435 8160777 YP_003033147.1 CDS TBMG_03158 NC_012943.1 3481582 3482112 D hypothetical protein 3481582..3482112 Mycobacterium tuberculosis KZN 1435 8160778 YP_003033148.1 CDS TBMG_03159 NC_012943.1 3482211 3483521 D transposase 3482211..3483521 Mycobacterium tuberculosis KZN 1435 8160779 YP_003033149.1 CDS TBMG_03160 NC_012943.1 3483599 3484768 D molybdenum cofactor biosynthesis protein moeB2 3483599..3484768 Mycobacterium tuberculosis KZN 1435 8160780 YP_003033150.1 CDS TBMG_03161 NC_012943.1 3484797 3485630 D thiosulfate sulfurtransferase cysA3 3484797..3485630 Mycobacterium tuberculosis KZN 1435 8160781 YP_003033151.1 CDS TBMG_03162 NC_012943.1 3485632 3485934 D hypothetical protein 3485632..3485934 Mycobacterium tuberculosis KZN 1435 8160782 YP_003033152.1 CDS TBMG_03163 NC_012943.1 3485955 3486398 D molybdenum cofactor biosynthesis protein E moaE1 3485955..3486398 Mycobacterium tuberculosis KZN 1435 8160783 YP_003033153.1 CDS TBMG_03164 NC_012943.1 3486395 3486997 D hypothetical protein 3486395..3486997 Mycobacterium tuberculosis KZN 1435 8160784 YP_003033154.1 CDS TBMG_03165 NC_012943.1 3487332 3488534 D cytochrome P450 141 cyp141 3487332..3488534 Mycobacterium tuberculosis KZN 1435 8160785 YP_003033155.1 CDS TBMG_03166 NC_012943.1 3488912 3489382 D hypothetical protein 3488912..3489382 Mycobacterium tuberculosis KZN 1435 8160786 YP_003033156.1 CDS TBMG_03167 NC_012943.1 3489392 3489886 D hypothetical protein 3489392..3489886 Mycobacterium tuberculosis KZN 1435 8160787 YP_003033157.1 CDS TBMG_03168 NC_012943.1 3490305 3491198 D transcriptional regulator 3490305..3491198 Mycobacterium tuberculosis KZN 1435 8160788 YP_003033158.1 CDS TBMG_03169 NC_012943.1 3491299 3492474 R PPE family protein complement(3491299..3492474) Mycobacterium tuberculosis KZN 1435 8160789 YP_003033159.1 CDS TBMG_03170 NC_012943.1 3492631 3492945 R hypothetical protein complement(3492631..3492945) Mycobacterium tuberculosis KZN 1435 8160790 YP_003033160.1 CDS TBMG_03171 NC_012943.1 3492970 3494004 D hypothetical protein 3492970..3494004 Mycobacterium tuberculosis KZN 1435 8160791 YP_003033161.1 CDS TBMG_04097 NC_012943.1 3493991 3494341 R hypothetical protein complement(3493991..3494341) Mycobacterium tuberculosis KZN 1435 8160792 YP_003033162.1 CDS TBMG_03172 NC_012943.1 3494423 3495016 R hypothetical protein complement(3494423..3495016) Mycobacterium tuberculosis KZN 1435 8160793 YP_003033163.1 CDS TBMG_04098 NC_012943.1 3495483 3495815 D hypothetical protein 3495483..3495815 Mycobacterium tuberculosis KZN 1435 8160794 YP_003033164.1 CDS TBMG_03173 NC_012943.1 3495798 3497189 R hypothetical protein complement(3495798..3497189) Mycobacterium tuberculosis KZN 1435 8160795 YP_003033165.1 CDS TBMG_03174 NC_012943.1 3497374 3498372 D hypothetical protein 3497374..3498372 Mycobacterium tuberculosis KZN 1435 8160796 YP_003033166.1 CDS TBMG_03175 NC_012943.1 3498352 3500088 R two component system sensor histidine kinase devS complement(3498352..3500088) Mycobacterium tuberculosis KZN 1435 8160797 YP_003033167.1 CDS TBMG_03176 NC_012943.1 3500085 3500738 R two component system transcriptional regulator devR complement(3500085..3500738) Mycobacterium tuberculosis KZN 1435 8160798 YP_003033168.1 CDS TBMG_03177 NC_012943.1 3500766 3501572 R hypothetical protein complement(3500766..3501572) Mycobacterium tuberculosis KZN 1435 8160799 YP_003033169.1 CDS TBMG_03178 NC_012943.1 3502157 3502555 D PPE family protein 3502157..3502555 Mycobacterium tuberculosis KZN 1435 8160800 YP_003033170.1 CDS TBMG_03179 NC_012943.1 3502617 3503759 D PPE family protein 3502617..3503759 Mycobacterium tuberculosis KZN 1435 8160801 YP_003033171.1 CDS TBMG_04099 NC_012943.1 3503768 3504100 R hypothetical protein complement(3503768..3504100) Mycobacterium tuberculosis KZN 1435 8160802 YP_003033172.1 CDS TBMG_03180 NC_012943.1 3504216 3504998 D monophosphatase 3504216..3504998 Mycobacterium tuberculosis KZN 1435 8160803 YP_003033173.1 CDS TBMG_03181 NC_012943.1 3505018 3506106 D pyruvate formate lyase activating protein pflA 3505018..3506106 Mycobacterium tuberculosis KZN 1435 8160804 YP_003033174.1 CDS TBMG_03182 NC_012943.1 3506186 3507592 D acyl-CoA dehydrogenase 3506186..3507592 Mycobacterium tuberculosis KZN 1435 8160805 YP_003033175.1 CDS TBMG_03183 NC_012943.1 3507613 3508818 D acyl-CoA dehydrogenase 3507613..3508818 Mycobacterium tuberculosis KZN 1435 8160806 YP_003033176.1 CDS TBMG_03184 NC_012943.1 3508918 3509889 D NADPH quinone oxidoreductase fadB4 3508918..3509889 Mycobacterium tuberculosis KZN 1435 8160807 YP_003033177.1 CDS TBMG_03185 NC_012943.1 3509941 3510369 R hypothetical protein complement(3509941..3510369) Mycobacterium tuberculosis KZN 1435 8160808 YP_003033178.1 CDS TBMG_03186 NC_012943.1 3510477 3510878 D response regulator 3510477..3510878 Mycobacterium tuberculosis KZN 1435 8160809 YP_003033179.1 CDS TBMG_03187 NC_012943.1 3510911 3512128 R PPE family protein complement(3510911..3512128) Mycobacterium tuberculosis KZN 1435 8160810 YP_003033180.1 CDS TBMG_03188 NC_012943.1 3512400 3512891 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 3512400..3512891 Mycobacterium tuberculosis KZN 1435 8160811 YP_003033181.1 CDS TBMG_03189 NC_012943.1 3512900 3513454 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 3512900..3513454 Mycobacterium tuberculosis KZN 1435 8160812 YP_003033182.1 CDS TBMG_03190 NC_012943.1 3513451 3514161 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 3513451..3514161 Mycobacterium tuberculosis KZN 1435 8160813 YP_003033183.1 CDS TBMG_03191 NC_012943.1 3514161 3515483 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 3514161..3515483 Mycobacterium tuberculosis KZN 1435 8160814 YP_003033184.1 CDS TBMG_03192 NC_012943.1 3515480 3516238 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 3515480..3516238 Mycobacterium tuberculosis KZN 1435 8160815 YP_003033185.1 CDS TBMG_03193 NC_012943.1 3516235 3517572 D NADH dehydrogenase subunit I F nuoF 3516235..3517572 Mycobacterium tuberculosis KZN 1435 8160816 YP_003033186.1 CDS TBMG_03194 NC_012943.1 3517569 3519989 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 3517569..3519989 Mycobacterium tuberculosis KZN 1435 8160817 YP_003033187.1 CDS TBMG_03195 NC_012943.1 3520105 3521337 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 3520105..3521337 Mycobacterium tuberculosis KZN 1435 8160818 YP_003033188.1 CDS TBMG_03196 NC_012943.1 3521309 3521965 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 3521309..3521965 Mycobacterium tuberculosis KZN 1435 8160819 YP_003033189.1 CDS TBMG_03197 NC_012943.1 3521962 3522750 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 3521962..3522750 Mycobacterium tuberculosis KZN 1435 8160820 YP_003033190.1 CDS TBMG_03198 NC_012943.1 3522747 3523046 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 3522747..3523046 Mycobacterium tuberculosis KZN 1435 8160821 YP_003033191.1 CDS TBMG_03199 NC_012943.1 3523057 3524958 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 3523057..3524958 Mycobacterium tuberculosis KZN 1435 8162494 YP_003033192.1 CDS TBMG_03200 NC_012943.1 3524955 3526616 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 3524955..3526616 Mycobacterium tuberculosis KZN 1435 8162583 YP_003033193.1 CDS TBMG_03201 NC_012943.1 3526613 3528208 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 3526613..3528208 Mycobacterium tuberculosis KZN 1435 8162584 YP_003033194.1 CDS TBMG_03202 NC_012943.1 3528214 3530145 R PPE family protein complement(3528214..3530145) Mycobacterium tuberculosis KZN 1435 8162585 YP_003033195.1 CDS TBMG_03203 NC_012943.1 3530161 3530802 R TetR family transcriptional regulator complement(3530161..3530802) Mycobacterium tuberculosis KZN 1435 8162586 YP_003033196.1 CDS TBMG_03204 NC_012943.1 3530813 3531970 R dioxygenase complement(3530813..3531970) Mycobacterium tuberculosis KZN 1435 8162587 YP_003033197.1 CDS TBMG_03205 NC_012943.1 3532031 3532468 R hypothetical protein complement(3532031..3532468) Mycobacterium tuberculosis KZN 1435 8162588 YP_003033198.1 CDS TBMG_03206 NC_012943.1 3532465 3533736 R hypothetical protein complement(3532465..3533736) Mycobacterium tuberculosis KZN 1435 8162589 YP_003033199.1 CDS TBMG_03207 NC_012943.1 3533766 3534728 R methanol dehydrogenase transcriptional regulator moxR3 complement(3533766..3534728) Mycobacterium tuberculosis KZN 1435 8162590 YP_003033200.1 CDS TBMG_03208 NC_012943.1 3534736 3535218 R hypothetical protein complement(3534736..3535218) Mycobacterium tuberculosis KZN 1435 8162591 YP_003033201.1 CDS TBMG_03209 NC_012943.1 3535215 3536174 R hypothetical protein complement(3535215..3536174) Mycobacterium tuberculosis KZN 1435 8162592 YP_003033202.1 CDS TBMG_03210 NC_012943.1 3536254 3536880 R TetR family transcriptional regulator complement(3536254..3536880) Mycobacterium tuberculosis KZN 1435 8162593 YP_003033203.1 CDS TBMG_03211 NC_012943.1 3536925 3538061 D hypothetical protein 3536925..3538061 Mycobacterium tuberculosis KZN 1435 8162594 YP_003033204.1 CDS TBMG_03212 NC_012943.1 3538061 3539185 D hypothetical protein 3538061..3539185 Mycobacterium tuberculosis KZN 1435 8162595 YP_003033205.1 CDS TBMG_03213 NC_012943.1 3539310 3540674 D flavin-containing monoamine oxidase aofH 3539310..3540674 Mycobacterium tuberculosis KZN 1435 8162596 YP_003033206.1 CDS TBMG_03214 NC_012943.1 3540669 3541568 R non-heme haloperoxidase hpx complement(3540669..3541568) Mycobacterium tuberculosis KZN 1435 8162597 YP_003033207.1 CDS TBMG_03215 NC_012943.1 3541705 3542187 R hypothetical protein complement(3541705..3542187) Mycobacterium tuberculosis KZN 1435 8162598 YP_003033208.1 CDS TBMG_03216 NC_012943.1 3542266 3542868 R TetR family transcriptional regulator complement(3542266..3542868) Mycobacterium tuberculosis KZN 1435 8162599 YP_003033209.1 CDS TBMG_03217 NC_012943.1 3542961 3543668 D short chain dehydrogenase 3542961..3543668 Mycobacterium tuberculosis KZN 1435 8162600 YP_003033210.1 CDS TBMG_03218 NC_012943.1 3543683 3545170 D catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 3543683..3545170 Mycobacterium tuberculosis KZN 1435 8162601 YP_003033211.1 CDS TBMG_03219 NC_012943.1 3545167 3546123 R epoxide hydrolase mesT complement(3545167..3546123) Mycobacterium tuberculosis KZN 1435 8162602 YP_003033212.1 CDS TBMG_03220 NC_012943.1 3546270 3547130 D peroxidase 3546270..3547130 Mycobacterium tuberculosis KZN 1435 8162603 YP_003033213.1 CDS TBMG_03221 NC_012943.1 3547261 3547620 D hypothetical protein 3547261..3547620 Mycobacterium tuberculosis KZN 1435 8162604 YP_003033214.1 CDS TBMG_03222 NC_012943.1 3547860 3548153 D hypothetical protein 3547860..3548153 Mycobacterium tuberculosis KZN 1435 8162605 YP_003033215.1 CDS TBMG_03223 NC_012943.1 3548366 3549730 D hypothetical protein 3548366..3549730 Mycobacterium tuberculosis KZN 1435 8162606 YP_003033216.1 CDS TBMG_03224 NC_012943.1 3550077 3550511 R hypothetical protein complement(3550077..3550511) Mycobacterium tuberculosis KZN 1435 8162607 YP_003033217.1 CDS TBMG_03225 NC_012943.1 3550514 3550966 R hypothetical protein complement(3550514..3550966) Mycobacterium tuberculosis KZN 1435 8162608 YP_003033218.1 CDS TBMG_03226 NC_012943.1 3551197 3551541 D hypothetical protein 3551197..3551541 Mycobacterium tuberculosis KZN 1435 8162609 YP_003033219.1 CDS TBMG_03227 NC_012943.1 3551538 3551867 D transcriptional regulator 3551538..3551867 Mycobacterium tuberculosis KZN 1435 8162610 YP_003033220.1 CDS TBMG_03228 NC_012943.1 3552405 3552752 D hypothetical protein 3552405..3552752 Mycobacterium tuberculosis KZN 1435 8162611 YP_003033221.1 CDS TBMG_03229 NC_012943.1 3552749 3553369 D hypothetical protein 3552749..3553369 Mycobacterium tuberculosis KZN 1435 8162612 YP_003033222.1 CDS TBMG_03230 NC_012943.1 3553529 3554794 R hypothetical protein complement(3553529..3554794) Mycobacterium tuberculosis KZN 1435 8162613 YP_003033223.1 CDS TBMG_03231 NC_012943.1 3555418 3556602 R transposase complement(3555418..3556602) Mycobacterium tuberculosis KZN 1435 8162614 YP_003033224.1 CDS TBMG_04100 NC_012943.1 3556736 3556960 R hypothetical protein complement(3556736..3556960) Mycobacterium tuberculosis KZN 1435 8162615 YP_003033225.1 CDS TBMG_04101 NC_012943.1 3556905 3557087 R hypothetical protein complement(3556905..3557087) Mycobacterium tuberculosis KZN 1435 8162616 YP_003033226.1 CDS TBMG_03232 NC_012943.1 3557667 3558131 D hypothetical protein 3557667..3558131 Mycobacterium tuberculosis KZN 1435 8162618 YP_003033227.1 CDS TBMG_03233 NC_012943.1 3558301 3561279 R hypothetical protein complement(3558301..3561279) Mycobacterium tuberculosis KZN 1435 8162619 YP_003033228.1 CDS TBMG_03234 NC_012943.1 3561371 3562393 R hypothetical protein complement(3561371..3562393) Mycobacterium tuberculosis KZN 1435 8162620 YP_003033229.1 CDS TBMG_03235 NC_012943.1 3562471 3563889 D hypothetical protein 3562471..3563889 Mycobacterium tuberculosis KZN 1435 8162621 YP_003033230.1 CDS TBMG_03236 NC_012943.1 3563895 3564794 D hypothetical protein 3563895..3564794 Mycobacterium tuberculosis KZN 1435 8162622 YP_003033231.1 CDS TBMG_03237 NC_012943.1 3564803 3565003 R hypothetical protein complement(3564803..3565003) Mycobacterium tuberculosis KZN 1435 8162623 YP_003033232.1 CDS TBMG_03238 NC_012943.1 3565131 3566474 D ABC transporter ATP-binding protein 3565131..3566474 Mycobacterium tuberculosis KZN 1435 8162624 YP_003033233.1 CDS TBMG_03239 NC_012943.1 3566508 3566786 R transcriptional regulator whib-like whiB7 complement(3566508..3566786) Mycobacterium tuberculosis KZN 1435 8162625 YP_003033234.1 CDS TBMG_03240 NC_012943.1 3567216 3569405 R ATP-dependent DNA helicase II uvrD2 complement(3567216..3569405) Mycobacterium tuberculosis KZN 1435 8162626 YP_003033235.1 CDS TBMG_03241 NC_012943.1 3569442 3569696 D glutaredoxin 3569442..3569696 Mycobacterium tuberculosis KZN 1435 8162627 YP_003033236.1 CDS nudC NC_012943.1 3569709 3570650 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(3569709..3570650) Mycobacterium tuberculosis KZN 1435 8162628 YP_003033237.1 CDS TBMG_03243 NC_012943.1 3570709 3571776 R transmembrane cation transporter complement(3570709..3571776) Mycobacterium tuberculosis KZN 1435 8162629 YP_003033238.1 CDS TBMG_03244 NC_012943.1 3571838 3575143 R ATP-dependent DNA helicase complement(3571838..3575143) Mycobacterium tuberculosis KZN 1435 8162630 YP_003033239.1 CDS TBMG_03245 NC_012943.1 3575140 3578307 R ATP-dependent DNA helicase complement(3575140..3578307) Mycobacterium tuberculosis KZN 1435 8162631 YP_003033240.1 CDS TBMG_03246 NC_012943.1 3578393 3578602 D hypothetical protein 3578393..3578602 Mycobacterium tuberculosis KZN 1435 8162632 YP_003033241.1 CDS TBMG_03247 NC_012943.1 3578633 3579418 D lipase lipV 3578633..3579418 Mycobacterium tuberculosis KZN 1435 8162633 YP_003033242.1 CDS TBMG_03248 NC_012943.1 3579421 3579726 D DNA-methyltransferase 3579421..3579726 Mycobacterium tuberculosis KZN 1435 8162634 YP_003033243.1 CDS TBMG_03249 NC_012943.1 3579733 3580611 R hypothetical protein complement(3579733..3580611) Mycobacterium tuberculosis KZN 1435 8162635 YP_003033244.1 CDS TBMG_03250 NC_012943.1 3580638 3581816 R The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; molybdopterin biosynthesis-like protein MoeZ complement(3580638..3581816) Mycobacterium tuberculosis KZN 1435 8162636 YP_003033245.1 CDS TBMG_03251 NC_012943.1 3581907 3582893 R hypothetical protein complement(3581907..3582893) Mycobacterium tuberculosis KZN 1435 8162637 YP_003033246.1 CDS TBMG_03252 NC_012943.1 3583110 3583796 D TetR family transcriptional regulator 3583110..3583796 Mycobacterium tuberculosis KZN 1435 8162638 YP_003033247.1 CDS TBMG_03253 NC_012943.1 3583783 3584070 R hypothetical protein complement(3583783..3584070) Mycobacterium tuberculosis KZN 1435 8162639 YP_003033248.1 CDS TBMG_04102 NC_012943.1 3584262 3584591 R helicase complement(3584262..3584591) Mycobacterium tuberculosis KZN 1435 8162640 YP_003033249.1 CDS TBMG_03254 NC_012943.1 3584380 3584940 D hypothetical protein 3584380..3584940 Mycobacterium tuberculosis KZN 1435 8162642 YP_003033250.1 CDS TBMG_03255 NC_012943.1 3584950 3585645 R hypothetical protein complement(3584950..3585645) Mycobacterium tuberculosis KZN 1435 8162641 YP_003033251.1 CDS TBMG_03256 NC_012943.1 3585904 3587487 D ATP-dependent RNA helicase rhlE 3585904..3587487 Mycobacterium tuberculosis KZN 1435 8162643 YP_003033252.1 CDS TBMG_03257 NC_012943.1 3587500 3588723 D hypothetical protein 3587500..3588723 Mycobacterium tuberculosis KZN 1435 8162644 YP_003033253.1 CDS TBMG_03258 NC_012943.1 3588799 3589599 R chromosome partitioning protein complement(3588799..3589599) Mycobacterium tuberculosis KZN 1435 8162645 YP_003033254.1 CDS TBMG_03259 NC_012943.1 3589678 3590364 D forms a homodimer in Mycobacterium tuberculosis; belongs to the dPGM superfamily; acid phosphatase 3589678..3590364 Mycobacterium tuberculosis KZN 1435 8162646 YP_003033255.1 CDS TBMG_03260 NC_012943.1 3590361 3591479 D isochorismate synthase entC 3590361..3591479 Mycobacterium tuberculosis KZN 1435 8162647 YP_003033256.1 CDS TBMG_03261 NC_012943.1 3591627 3591959 D acetyltransferase 3591627..3591959 Mycobacterium tuberculosis KZN 1435 8162648 YP_003033257.1 CDS TBMG_03262 NC_012943.1 3591911 3592342 R hypothetical protein complement(3591911..3592342) Mycobacterium tuberculosis KZN 1435 8162649 YP_003033258.1 CDS TBMG_03263 NC_012943.1 3592575 3593540 D hypothetical protein 3592575..3593540 Mycobacterium tuberculosis KZN 1435 8162650 YP_003033259.1 CDS TBMG_03264 NC_012943.1 3593833 3594087 D transcriptional regulator whib-like whiB1 3593833..3594087 Mycobacterium tuberculosis KZN 1435 8162651 YP_003033260.1 CDS TBMG_03265 NC_012943.1 3594149 3595654 R two component system sensor kinase complement(3594149..3595654) Mycobacterium tuberculosis KZN 1435 8162652 YP_003033261.1 CDS TBMG_03266 NC_012943.1 3595671 3595910 R acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(3595671..3595910) Mycobacterium tuberculosis KZN 1435 8162653 YP_003033262.1 CDS TBMG_03267 NC_012943.1 3596171 3596476 R anti-sigma factor complement(3596171..3596476) Mycobacterium tuberculosis KZN 1435 8162654 YP_003033263.1 CDS TBMG_03268 NC_012943.1 3596473 3597024 R hypothetical protein complement(3596473..3597024) Mycobacterium tuberculosis KZN 1435 8162655 YP_003033264.1 CDS TBMG_03269 NC_012943.1 3597021 3597788 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(3597021..3597788) Mycobacterium tuberculosis KZN 1435 8162656 YP_003033265.1 CDS TBMG_03270 NC_012943.1 3597971 3598819 D short chain dehydrogenase 3597971..3598819 Mycobacterium tuberculosis KZN 1435 8162657 YP_003033266.1 CDS TBMG_03271 NC_012943.1 3598755 3598943 D hypothetical protein 3598755..3598943 Mycobacterium tuberculosis KZN 1435 8162658 YP_003033267.1 CDS TBMG_03272 NC_012943.1 3598921 3599139 D hypothetical protein 3598921..3599139 Mycobacterium tuberculosis KZN 1435 8162659 YP_003033268.1 CDS TBMG_03273 NC_012943.1 3599136 3600560 R transferase complement(3599136..3600560) Mycobacterium tuberculosis KZN 1435 8162660 YP_003033269.1 CDS TBMG_03274 NC_012943.1 3600684 3601442 R hypothetical protein complement(3600684..3601442) Mycobacterium tuberculosis KZN 1435 8162661 YP_003033270.1 CDS TBMG_03275 NC_012943.1 3601497 3602849 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 3601497..3602849 Mycobacterium tuberculosis KZN 1435 8162662 YP_003033271.1 CDS TBMG_03276 NC_012943.1 3602846 3603838 D hypothetical protein 3602846..3603838 Mycobacterium tuberculosis KZN 1435 8162663 YP_003033272.1 CDS TBMG_03277 NC_012943.1 3603871 3605154 R linoleoyl-CoA desaturase complement(3603871..3605154) Mycobacterium tuberculosis KZN 1435 8163622 YP_003033273.1 CDS TBMG_03278 NC_012943.1 3605232 3606374 R oxidoreductase complement(3605232..3606374) Mycobacterium tuberculosis KZN 1435 8162087 YP_003033274.1 CDS TBMG_03279 NC_012943.1 3606484 3606993 R hypothetical protein complement(3606484..3606993) Mycobacterium tuberculosis KZN 1435 8162088 YP_003033275.1 CDS TBMG_03280 NC_012943.1 3606990 3607877 R transcriptional regulator pvdS complement(3606990..3607877) Mycobacterium tuberculosis KZN 1435 8162089 YP_003033276.1 CDS TBMG_03281 NC_012943.1 3607901 3608503 R hypothetical protein complement(3607901..3608503) Mycobacterium tuberculosis KZN 1435 8162090 YP_003033277.1 CDS TBMG_03282 NC_012943.1 3608494 3609309 R hypothetical protein complement(3608494..3609309) Mycobacterium tuberculosis KZN 1435 8162091 YP_003033278.1 CDS TBMG_03283 NC_012943.1 3609420 3610061 D hypothetical protein 3609420..3610061 Mycobacterium tuberculosis KZN 1435 8162092 YP_003033279.1 CDS TBMG_03284 NC_012943.1 3610079 3611236 R membrane transporter complement(3610079..3611236) Mycobacterium tuberculosis KZN 1435 8162093 YP_003033280.1 CDS TBMG_03285 NC_012943.1 3611241 3611723 R hypothetical protein complement(3611241..3611723) Mycobacterium tuberculosis KZN 1435 8162094 YP_003033281.1 CDS TBMG_03286 NC_012943.1 3611784 3612518 R hypothetical protein complement(3611784..3612518) Mycobacterium tuberculosis KZN 1435 8162095 YP_003033282.1 CDS TBMG_03287 NC_012943.1 3612577 3615723 R membrane transporter complement(3612577..3615723) Mycobacterium tuberculosis KZN 1435 8162096 YP_003033283.1 CDS TBMG_03288 NC_012943.1 3615802 3618651 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(3615802..3618651) Mycobacterium tuberculosis KZN 1435 8162097 YP_003033284.1 CDS TBMG_03289 NC_012943.1 3618730 3619374 R hypothetical protein complement(3618730..3619374) Mycobacterium tuberculosis KZN 1435 8162098 YP_003033285.1 CDS TBMG_03290 NC_012943.1 3619690 3620331 R hypothetical protein complement(3619690..3620331) Mycobacterium tuberculosis KZN 1435 8162099 YP_003033286.1 CDS TBMG_03291 NC_012943.1 3620369 3621211 R hypothetical protein complement(3620369..3621211) Mycobacterium tuberculosis KZN 1435 8162100 YP_003033287.1 CDS TBMG_03292 NC_012943.1 3621279 3623042 R lipoprotein LpqB complement(3621279..3623042) Mycobacterium tuberculosis KZN 1435 8162101 YP_003033288.1 CDS TBMG_03293 NC_012943.1 3623030 3624733 R two component system sensor histidine kinase mtrB complement(3623030..3624733) Mycobacterium tuberculosis KZN 1435 8162102 YP_003033289.1 CDS TBMG_03294 NC_012943.1 3624783 3625469 R two component system transcriptional regulator mtrA complement(3624783..3625469) Mycobacterium tuberculosis KZN 1435 8162103 YP_003033290.1 CDS TBMG_03295 NC_012943.1 3625539 3626183 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(3625539..3626183) Mycobacterium tuberculosis KZN 1435 8162104 YP_003033291.1 CDS TBMG_03296 NC_012943.1 3626280 3627767 R catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase complement(3626280..3627767) Mycobacterium tuberculosis KZN 1435 8162105 YP_003033292.1 CDS TBMG_03297 NC_012943.1 3627872 3628507 R TetR family transcriptional regulator complement(3627872..3628507) Mycobacterium tuberculosis KZN 1435 8162106 YP_003033293.1 CDS TBMG_03298 NC_012943.1 3628504 3628686 R rubredoxin rubB complement(3628504..3628686) Mycobacterium tuberculosis KZN 1435 8162107 YP_003033294.1 CDS TBMG_03299 NC_012943.1 3628691 3628858 R rubredoxin rubA complement(3628691..3628858) Mycobacterium tuberculosis KZN 1435 8162108 YP_003033295.1 CDS TBMG_03300 NC_012943.1 3628858 3630108 R transmembrane alkane 1-monooxygenase alkB complement(3628858..3630108) Mycobacterium tuberculosis KZN 1435 8162109 YP_003033296.1 CDS TBMG_03301 NC_012943.1 3630217 3631704 R hypothetical protein complement(3630217..3631704) Mycobacterium tuberculosis KZN 1435 8162110 YP_003033297.1 CDS TBMG_03302 NC_012943.1 3631759 3633183 D hypothetical protein 3631759..3633183 Mycobacterium tuberculosis KZN 1435 8162111 YP_003033298.1 CDS TBMG_03303 NC_012943.1 3633161 3634387 R mannose-6-phosphate isomerase complement(3633161..3634387) Mycobacterium tuberculosis KZN 1435 8162112 YP_003033299.1 CDS TBMG_03304 NC_012943.1 3634395 3635435 R hypothetical protein complement(3634395..3635435) Mycobacterium tuberculosis KZN 1435 8162113 YP_003033300.1 CDS manB NC_012943.1 3635432 3636829 R converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase/phosphoglucomutase complement(3635432..3636829) Mycobacterium tuberculosis KZN 1435 8162114 YP_003033301.1 CDS TBMG_03306 NC_012943.1 3636931 3637422 R hypothetical protein complement(3636931..3637422) Mycobacterium tuberculosis KZN 1435 8162115 YP_003033302.1 CDS TBMG_03307 NC_012943.1 3637437 3637964 D hypothetical protein 3637437..3637964 Mycobacterium tuberculosis KZN 1435 8162116 YP_003033303.1 CDS TBMG_03308 NC_012943.1 3637992 3638363 R transcriptional regulator whib-like whiB2 complement(3637992..3638363) Mycobacterium tuberculosis KZN 1435 8162117 YP_003033304.1 CDS TBMG_03309 NC_012943.1 3638663 3639658 D catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); LPPG:FO 2-phospho-L-lactate transferase 3638663..3639658 Mycobacterium tuberculosis KZN 1435 8162118 YP_003033305.1 CDS TBMG_03310 NC_012943.1 3639655 3641001 D catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); F420-0--gamma-glutamyl ligase 3639655..3641001 Mycobacterium tuberculosis KZN 1435 8162119 YP_003033306.1 CDS TBMG_04103 NC_012943.1 3641034 3641147 D hypothetical protein 3641034..3641147 Mycobacterium tuberculosis KZN 1435 8162120 YP_003033307.1 CDS TBMG_03311 NC_012943.1 3641297 3642958 D DNA methylase 3641297..3642958 Mycobacterium tuberculosis KZN 1435 8162121 YP_003033308.1 CDS TBMG_03312 NC_012943.1 3643018 3644097 R D-alpha-D-mannose-1-phosphate guanylyltransferase manB complement(3643018..3644097) Mycobacterium tuberculosis KZN 1435 8162122 YP_003033309.1 CDS TBMG_03313 NC_012943.1 3644099 3645022 R dTDP-rha:a-D-glcnac-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase wbbL1 complement(3644099..3645022) Mycobacterium tuberculosis KZN 1435 8162123 YP_003033310.1 CDS TBMG_03314 NC_012943.1 3645015 3645929 R dTDP-6-deoxy-L-lyxo-4-hexulose reductase rmlD complement(3645015..3645929) Mycobacterium tuberculosis KZN 1435 8162124 YP_003033311.1 CDS TBMG_03315 NC_012943.1 3646005 3647501 D hypothetical protein 3646005..3647501 Mycobacterium tuberculosis KZN 1435 8162125 YP_003033312.1 CDS TBMG_03316 NC_012943.1 3647489 3648229 D hypothetical protein 3647489..3648229 Mycobacterium tuberculosis KZN 1435 8162126 YP_003033313.1 CDS TBMG_03317 NC_012943.1 3648354 3648635 D hypothetical protein 3648354..3648635 Mycobacterium tuberculosis KZN 1435 8162127 YP_003033314.1 CDS TBMG_03318 NC_012943.1 3648646 3650802 D metal cation transporting P-type ATPase ctpC 3648646..3650802 Mycobacterium tuberculosis KZN 1435 8162128 YP_003033315.1 CDS TBMG_03319 NC_012943.1 3650799 3651467 R hypothetical protein complement(3650799..3651467) Mycobacterium tuberculosis KZN 1435 8162129 YP_003033316.1 CDS TBMG_03320 NC_012943.1 3651568 3652752 D hypothetical protein 3651568..3652752 Mycobacterium tuberculosis KZN 1435 8162130 YP_003033317.1 CDS TBMG_03321 NC_012943.1 3652757 3655051 D transmembrane carbonic anhydrase 3652757..3655051 Mycobacterium tuberculosis KZN 1435 8162131 YP_003033318.1 CDS TBMG_03322 NC_012943.1 3655040 3656209 R acyl-CoA dehydrogenase complement(3655040..3656209) Mycobacterium tuberculosis KZN 1435 8162132 YP_003033319.1 CDS TBMG_03323 NC_012943.1 3656234 3656758 R phosphoribosylaminoimidazole carboxylase catalytic subunit purE complement(3656234..3656758) Mycobacterium tuberculosis KZN 1435 8162133 YP_003033320.1 CDS TBMG_03324 NC_012943.1 3656755 3658044 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(3656755..3658044) Mycobacterium tuberculosis KZN 1435 8162134 YP_003033321.1 CDS TBMG_03325 NC_012943.1 3657998 3658816 D hypothetical protein 3657998..3658816 Mycobacterium tuberculosis KZN 1435 8162136 YP_003033322.1 CDS TBMG_03326 NC_012943.1 3658771 3659289 R hypothetical protein complement(3658771..3659289) Mycobacterium tuberculosis KZN 1435 8162135 YP_003033323.1 CDS TBMG_03327 NC_012943.1 3659332 3660132 R biotin-protein ligase complement(3659332..3660132) Mycobacterium tuberculosis KZN 1435 8162137 YP_003033324.1 CDS TBMG_03328 NC_012943.1 3660182 3661828 D propionyl-CoA carboxylase subunit beta 3660182..3661828 Mycobacterium tuberculosis KZN 1435 8162138 YP_003033325.1 CDS TBMG_03329 NC_012943.1 3661809 3662279 D hypothetical protein 3661809..3662279 Mycobacterium tuberculosis KZN 1435 8162139 YP_003033326.1 CDS TBMG_03330 NC_012943.1 3662276 3662944 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3662276..3662944 Mycobacterium tuberculosis KZN 1435 8162140 YP_003033327.1 CDS TBMG_03331 NC_012943.1 3662913 3663878 D thiosulfate sulfurtransferase sseA 3662913..3663878 Mycobacterium tuberculosis KZN 1435 8162141 YP_003033328.1 CDS TBMG_03332 NC_012943.1 3663875 3664306 D hypothetical protein 3663875..3664306 Mycobacterium tuberculosis KZN 1435 8162142 YP_003033329.1 CDS TBMG_03333 NC_012943.1 3664414 3666216 D bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 3664414..3666216 Mycobacterium tuberculosis KZN 1435 8162143 YP_003033330.1 CDS TBMG_03334 NC_012943.1 3666226 3667011 R Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is a general stress response regulator; expressed in stationary phase and under nitrogen depletion and cold shock; RNA polymerase sigma factor SigF complement(3666226..3667011) Mycobacterium tuberculosis KZN 1435 8162144 YP_003033331.1 CDS TBMG_03335 NC_012943.1 3667008 3667634 R anti-sigma factor rsbW complement(3667008..3667634) Mycobacterium tuberculosis KZN 1435 8162145 YP_003033332.1 CDS TBMG_03336 NC_012943.1 3667643 3668056 R hypothetical protein complement(3667643..3668056) Mycobacterium tuberculosis KZN 1435 8162146 YP_003033333.1 CDS TBMG_03337 NC_012943.1 3668091 3668468 R hypothetical protein complement(3668091..3668468) Mycobacterium tuberculosis KZN 1435 8162147 YP_003033334.1 CDS TBMG_03338 NC_012943.1 3668502 3669851 R catalyzes the formation of 2-aminoadipate 6-semiladehyde and glutamate from lysine and 2-oxoglutarate; L-lysine aminotransferase complement(3668502..3669851) Mycobacterium tuberculosis KZN 1435 8162148 YP_003033335.1 CDS TBMG_03339 NC_012943.1 3669902 3670354 R transcriptional regulator, asnC-family complement(3669902..3670354) Mycobacterium tuberculosis KZN 1435 8162149 YP_003033336.1 CDS TBMG_03340 NC_012943.1 3670385 3671632 D hypothetical protein 3670385..3671632 Mycobacterium tuberculosis KZN 1435 8162150 YP_003033337.1 CDS TBMG_03341 NC_012943.1 3671659 3673143 D piperideine-6-carboxilic acid dehydrogenase pcd 3671659..3673143 Mycobacterium tuberculosis KZN 1435 8162151 YP_003033338.1 CDS TBMG_03342 NC_012943.1 3673243 3674052 R hypothetical protein complement(3673243..3674052) Mycobacterium tuberculosis KZN 1435 8162152 YP_003033339.1 CDS TBMG_03343 NC_012943.1 3674123 3674788 D TetR family transcriptional regulator 3674123..3674788 Mycobacterium tuberculosis KZN 1435 8162153 YP_003033340.1 CDS TBMG_03344 NC_012943.1 3674832 3679373 D ATP-dependent helicase lhr 3674832..3679373 Mycobacterium tuberculosis KZN 1435 8162154 YP_003033341.1 CDS TBMG_03345 NC_012943.1 3679377 3680144 D endonuclease VIII nei 3679377..3680144 Mycobacterium tuberculosis KZN 1435 8162155 YP_003033342.1 CDS TBMG_03346 NC_012943.1 3680167 3681081 R esterase lipoprotein lpqC complement(3680167..3681081) Mycobacterium tuberculosis KZN 1435 8162156 YP_003033343.1 CDS TBMG_03347 NC_012943.1 3681108 3684020 R arylsulfatase complement(3681108..3684020) Mycobacterium tuberculosis KZN 1435 8162157 YP_003033344.1 CDS TBMG_03348 NC_012943.1 3684040 3684957 R hypothetical protein complement(3684040..3684957) Mycobacterium tuberculosis KZN 1435 8162158 YP_003033345.1 CDS TBMG_03349 NC_012943.1 3684969 3685634 R phosphate-transport system transcriptional regulator phoY1 complement(3684969..3685634) Mycobacterium tuberculosis KZN 1435 8162159 YP_003033346.1 CDS TBMG_03350 NC_012943.1 3685742 3687499 R glycerol-3-phosphate dehydrogenase glpD2 complement(3685742..3687499) Mycobacterium tuberculosis KZN 1435 8162160 YP_003033347.1 CDS TBMG_03351 NC_012943.1 3687580 3689025 R catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase complement(3687580..3689025) Mycobacterium tuberculosis KZN 1435 8162161 YP_003033348.1 CDS TBMG_03352 NC_012943.1 3689198 3689677 D hypothetical protein 3689198..3689677 Mycobacterium tuberculosis KZN 1435 8162162 YP_003033349.1 CDS TBMG_03353 NC_012943.1 3689696 3690865 R N-acyl-L-amino acid amidohydrolase amiA1 complement(3689696..3690865) Mycobacterium tuberculosis KZN 1435 8162163 YP_003033350.1 CDS TBMG_03354 NC_012943.1 3690862 3692046 R amidohydrolase complement(3690862..3692046) Mycobacterium tuberculosis KZN 1435 8162164 YP_003033351.1 CDS TBMG_03355 NC_012943.1 3692111 3692917 D catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 3692111..3692917 Mycobacterium tuberculosis KZN 1435 8162165 YP_003033352.1 CDS TBMG_03356 NC_012943.1 3692921 3694525 D phosphomannomutase pmmB 3692921..3694525 Mycobacterium tuberculosis KZN 1435 8163143 YP_003033353.1 CDS upp NC_012943.1 3694527 3695150 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(3694527..3695150) Mycobacterium tuberculosis KZN 1435 8163144 YP_003033354.1 CDS TBMG_03358 NC_012943.1 3695255 3696154 D acid phosphatase 3695255..3696154 Mycobacterium tuberculosis KZN 1435 8163145 YP_003033355.1 CDS TBMG_03359 NC_012943.1 3696178 3697440 D hypothetical protein 3696178..3697440 Mycobacterium tuberculosis KZN 1435 8163146 YP_003033356.1 CDS TBMG_03360 NC_012943.1 3697461 3698387 R hypothetical protein complement(3697461..3698387) Mycobacterium tuberculosis KZN 1435 8163147 YP_003033357.1 CDS TBMG_04104 NC_012943.1 3698413 3698583 R hypothetical protein complement(3698413..3698583) Mycobacterium tuberculosis KZN 1435 8163148 YP_003033358.1 CDS TBMG_03361 NC_012943.1 3698762 3699073 R secreted protein antigen complement(3698762..3699073) Mycobacterium tuberculosis KZN 1435 8163149 YP_003033359.1 CDS TBMG_03362 NC_012943.1 3699144 3700241 R catalyzes the formation of inosine from adenosine; adenosine deaminase complement(3699144..3700241) Mycobacterium tuberculosis KZN 1435 8163150 YP_003033360.1 CDS deoA NC_012943.1 3700241 3701524 R Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase complement(3700241..3701524) Mycobacterium tuberculosis KZN 1435 8163151 YP_003033361.1 CDS TBMG_03364 NC_012943.1 3701521 3702009 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(3701521..3702009) Mycobacterium tuberculosis KZN 1435 8163152 YP_003033362.1 CDS TBMG_03365 NC_012943.1 3702063 3702497 D succinate dehydrogenase cytochrome B-556 subunit sdhC 3702063..3702497 Mycobacterium tuberculosis KZN 1435 8163153 YP_003033363.1 CDS TBMG_03366 NC_012943.1 3702494 3702928 D succinate dehydrogenase hydrophobic membrane anchor subunit sdhD 3702494..3702928 Mycobacterium tuberculosis KZN 1435 8163154 YP_003033364.1 CDS sdhA NC_012943.1 3703057 3704829 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 3703057..3704829 Mycobacterium tuberculosis KZN 1435 8163155 YP_003033365.1 CDS sdhB NC_012943.1 3704829 3705620 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 3704829..3705620 Mycobacterium tuberculosis KZN 1435 8163156 YP_003033366.1 CDS TBMG_03369 NC_012943.1 3705699 3706127 R toxin complement(3705699..3706127) Mycobacterium tuberculosis KZN 1435 8163157 YP_003033367.1 CDS TBMG_03370 NC_012943.1 3706131 3706373 R antitoxin complement(3706131..3706373) Mycobacterium tuberculosis KZN 1435 8163158 YP_003033368.1 CDS TBMG_03371 NC_012943.1 3706495 3707127 R methyltransferase complement(3706495..3707127) Mycobacterium tuberculosis KZN 1435 8163159 YP_003033369.1 CDS TBMG_03372 NC_012943.1 3707106 3707771 R moaD-moaE fusion protein moaX complement(3707106..3707771) Mycobacterium tuberculosis KZN 1435 8163160 YP_003033370.1 CDS moaC NC_012943.1 3707772 3708326 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(3707772..3708326) Mycobacterium tuberculosis KZN 1435 8163161 YP_003033371.1 CDS TBMG_03374 NC_012943.1 3708302 3708676 R pterin-4-alpha-carbinolamine dehydratase complement(3708302..3708676) Mycobacterium tuberculosis KZN 1435 8163162 YP_003033372.1 CDS TBMG_03375 NC_012943.1 3708737 3709621 R transposase complement(3708737..3709621) Mycobacterium tuberculosis KZN 1435 8163163 YP_003033373.1 CDS TBMG_03376 NC_012943.1 3709672 3709998 R transposase complement(3709672..3709998) Mycobacterium tuberculosis KZN 1435 8163164 YP_003033374.1 CDS TBMG_03377 NC_012943.1 3710047 3710250 R alternative RNA polymerase sigma factor sigJ complement(3710047..3710250) Mycobacterium tuberculosis KZN 1435 8163165 YP_003033375.1 CDS TBMG_03378 NC_012943.1 3710301 3711617 D hypothetical protein 3710301..3711617 Mycobacterium tuberculosis KZN 1435 8163166 YP_003033376.1 CDS TBMG_03379 NC_012943.1 3711686 3712903 D penicillin-binding protein dacB1 3711686..3712903 Mycobacterium tuberculosis KZN 1435 8163167 YP_003033377.1 CDS TBMG_03380 NC_012943.1 3712999 3714507 D hypothetical protein 3712999..3714507 Mycobacterium tuberculosis KZN 1435 8163168 YP_003033378.1 CDS TBMG_03381 NC_012943.1 3714504 3715655 D N-acetylglucosamine-6-phosphate deacetylase nagA 3714504..3715655 Mycobacterium tuberculosis KZN 1435 8163169 YP_003033379.1 CDS TBMG_03382 NC_012943.1 3715846 3716691 R hypothetical protein complement(3715846..3716691) Mycobacterium tuberculosis KZN 1435 8163170 YP_003033380.1 CDS TBMG_03383 NC_012943.1 3716668 3717147 D hypothetical protein 3716668..3717147 Mycobacterium tuberculosis KZN 1435 8163172 YP_003033381.1 CDS TBMG_03384 NC_012943.1 3717166 3717606 D transcriptional regulator, merR-family 3717166..3717606 Mycobacterium tuberculosis KZN 1435 8163171 YP_003033382.1 CDS TBMG_03385 NC_012943.1 3717640 3718509 R hypothetical protein complement(3717640..3718509) Mycobacterium tuberculosis KZN 1435 8163173 YP_003033383.1 CDS TBMG_03386 NC_012943.1 3718530 3719540 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3718530..3719540) Mycobacterium tuberculosis KZN 1435 8163174 YP_003033384.1 CDS TBMG_03387 NC_012943.1 3719711 3720457 D hypothetical protein 3719711..3720457 Mycobacterium tuberculosis KZN 1435 8163175 YP_003033385.1 CDS TBMG_03388 NC_012943.1 3720524 3721753 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(3720524..3721753) Mycobacterium tuberculosis KZN 1435 8163176 YP_003033386.1 CDS TBMG_03389 NC_012943.1 3722036 3723385 D catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 3722036..3723385 Mycobacterium tuberculosis KZN 1435 8163177 YP_003033387.1 CDS metX NC_012943.1 3723397 3724536 D Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 3723397..3724536 Mycobacterium tuberculosis KZN 1435 8163178 YP_003033388.1 CDS TBMG_03391 NC_012943.1 3724533 3725264 D methyltransferase/methylase 3724533..3725264 Mycobacterium tuberculosis KZN 1435 8163179 YP_003033389.1 CDS TBMG_03392 NC_012943.1 3725273 3732871 R PPE family protein complement(3725273..3732871) Mycobacterium tuberculosis KZN 1435 8163180 YP_003033390.1 CDS TBMG_04105 NC_012943.1 3732935 3733951 R PE-PGRS family protein complement(3732935..3733951) Mycobacterium tuberculosis KZN 1435 8163181 YP_003033391.1 CDS TBMG_04106 NC_012943.1 3734109 3738635 R hypothetical protein complement(3734109..3738635) Mycobacterium tuberculosis KZN 1435 8163182 YP_003033392.1 CDS TBMG_03395 NC_012943.1 3739059 3739316 R hypothetical protein complement(3739059..3739316) Mycobacterium tuberculosis KZN 1435 8163183 YP_003033393.1 CDS TBMG_03396 NC_012943.1 3739572 3749045 R PPE family protein complement(3739572..3749045) Mycobacterium tuberculosis KZN 1435 8163184 YP_003033394.1 CDS TBMG_03397 NC_012943.1 3749083 3749574 R hypothetical protein complement(3749083..3749574) Mycobacterium tuberculosis KZN 1435 8163185 YP_003033395.1 CDS TBMG_03398 NC_012943.1 3749626 3750117 D transposase 3749626..3750117 Mycobacterium tuberculosis KZN 1435 8163186 YP_003033396.1 CDS TBMG_03399 NC_012943.1 3750154 3751098 R transposase complement(3750154..3751098) Mycobacterium tuberculosis KZN 1435 8163187 YP_003033397.1 CDS TBMG_03400 NC_012943.1 3751189 3751425 R transposase complement(3751189..3751425) Mycobacterium tuberculosis KZN 1435 8163188 YP_003033398.1 CDS TBMG_03401 NC_012943.1 3751813 3763176 R PPE family protein complement(3751813..3763176) Mycobacterium tuberculosis KZN 1435 8163189 YP_003033399.1 CDS TBMG_03402 NC_012943.1 3763207 3764001 R oxidoreductase complement(3763207..3764001) Mycobacterium tuberculosis KZN 1435 8163190 YP_003033400.1 CDS TBMG_03403 NC_012943.1 3764083 3764454 R oxidoreductase complement(3764083..3764454) Mycobacterium tuberculosis KZN 1435 8163191 YP_003033401.1 CDS TBMG_03404 NC_012943.1 3764597 3764857 R oxidoreductase complement(3764597..3764857) Mycobacterium tuberculosis KZN 1435 8163192 YP_003033402.1 CDS TBMG_03405 NC_012943.1 3764972 3765361 D hypothetical protein 3764972..3765361 Mycobacterium tuberculosis KZN 1435 8163193 YP_003033403.1 CDS TBMG_03406 NC_012943.1 3765375 3765668 R hypothetical protein complement(3765375..3765668) Mycobacterium tuberculosis KZN 1435 8163194 YP_003033404.1 CDS TBMG_03407 NC_012943.1 3765665 3766510 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(3765665..3766510) Mycobacterium tuberculosis KZN 1435 8163195 YP_003033405.1 CDS TBMG_03408 NC_012943.1 3766634 3766909 D hypothetical protein 3766634..3766909 Mycobacterium tuberculosis KZN 1435 8163196 YP_003033406.1 CDS TBMG_03409 NC_012943.1 3766906 3767163 D hypothetical protein 3766906..3767163 Mycobacterium tuberculosis KZN 1435 8163197 YP_003033407.1 CDS TBMG_03410 NC_012943.1 3767205 3768395 D oxidoreductase 3767205..3768395 Mycobacterium tuberculosis KZN 1435 8163198 YP_003033408.1 CDS TBMG_03411 NC_012943.1 3768512 3768880 D hypothetical protein 3768512..3768880 Mycobacterium tuberculosis KZN 1435 8163199 YP_003033409.1 CDS TBMG_03412 NC_012943.1 3768877 3769428 R hypothetical protein complement(3768877..3769428) Mycobacterium tuberculosis KZN 1435 8163200 YP_003033410.1 CDS TBMG_03413 NC_012943.1 3769435 3770016 R ATP/GTP-binding protein complement(3769435..3770016) Mycobacterium tuberculosis KZN 1435 8163201 YP_003033411.1 CDS TBMG_03414 NC_012943.1 3769997 3770365 R hypothetical protein complement(3769997..3770365) Mycobacterium tuberculosis KZN 1435 8163202 YP_003033412.1 CDS TBMG_03415 NC_012943.1 3770343 3770735 R hypothetical protein complement(3770343..3770735) Mycobacterium tuberculosis KZN 1435 8163203 YP_003033413.1 CDS TBMG_03416 NC_012943.1 3770732 3773362 R hypothetical protein complement(3770732..3773362) Mycobacterium tuberculosis KZN 1435 8163204 YP_003033414.1 CDS TBMG_03417 NC_012943.1 3773598 3774062 D tRNA/rRNA methylase spoU 3773598..3774062 Mycobacterium tuberculosis KZN 1435 8163205 YP_003033415.1 CDS TBMG_03418 NC_012943.1 3774327 3776204 D hypothetical protein 3774327..3776204 Mycobacterium tuberculosis KZN 1435 8163206 YP_003033416.1 CDS TBMG_03419 NC_012943.1 3776205 3776849 R oxidoreductase complement(3776205..3776849) Mycobacterium tuberculosis KZN 1435 8163207 YP_003033417.1 CDS TBMG_03420 NC_012943.1 3776848 3777282 D hypothetical protein 3776848..3777282 Mycobacterium tuberculosis KZN 1435 8163378 YP_003033418.1 CDS dnaE2 NC_012943.1 3777371 3780667 R DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase complement(3777371..3780667) Mycobacterium tuberculosis KZN 1435 8163208 YP_003033419.1 CDS TBMG_03422 NC_012943.1 3780802 3782142 D hypothetical protein 3780802..3782142 Mycobacterium tuberculosis KZN 1435 8164323 YP_003033420.1 CDS TBMG_03423 NC_012943.1 3782184 3783359 D trehalose 6-phosphate phosphatase otsB2 3782184..3783359 Mycobacterium tuberculosis KZN 1435 8164324 YP_003033421.1 CDS TBMG_03424 NC_012943.1 3783596 3784237 D enoyl-CoA hydratase echA18 3783596..3784237 Mycobacterium tuberculosis KZN 1435 8164325 YP_003033422.1 CDS TBMG_03425 NC_012943.1 3784238 3784486 D enoyl-CoA hydratase echA18_1 3784238..3784486 Mycobacterium tuberculosis KZN 1435 8164326 YP_003033423.1 CDS TBMG_03426 NC_012943.1 3784491 3785918 D amidase 3784491..3785918 Mycobacterium tuberculosis KZN 1435 8164327 YP_003033424.1 CDS TBMG_03427 NC_012943.1 3786026 3786679 D hypothetical protein 3786026..3786679 Mycobacterium tuberculosis KZN 1435 8164328 YP_003033425.1 CDS TBMG_03428 NC_012943.1 3786718 3788223 R cyclase complement(3786718..3788223) Mycobacterium tuberculosis KZN 1435 8164329 YP_003033426.1 CDS TBMG_03429 NC_012943.1 3788228 3789118 R hypothetical protein complement(3788228..3789118) Mycobacterium tuberculosis KZN 1435 8164330 YP_003033427.1 CDS TBMG_04107 NC_012943.1 3789127 3790737 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(3789127..3790737) Mycobacterium tuberculosis KZN 1435 8164331 YP_003033428.1 CDS TBMG_04108 NC_012943.1 3790682 3790963 R 1-deoxy-D-xylulose-5-phosphate synthase complement(3790682..3790963) Mycobacterium tuberculosis KZN 1435 8164332 YP_003033429.1 CDS TBMG_03431 NC_012943.1 3790960 3791955 R lytB-related protein lytB1 complement(3790960..3791955) Mycobacterium tuberculosis KZN 1435 8164333 YP_003033430.1 CDS TBMG_03432 NC_012943.1 3791949 3793001 R polyprenyl synthetase complement(3791949..3793001) Mycobacterium tuberculosis KZN 1435 8164334 YP_003033431.1 CDS TBMG_03433 NC_012943.1 3793755 3794147 R toxin complement(3793755..3794147) Mycobacterium tuberculosis KZN 1435 8164335 YP_003033432.1 CDS TBMG_03434 NC_012943.1 3794147 3794455 R antitoxin complement(3794147..3794455) Mycobacterium tuberculosis KZN 1435 8164336 YP_003033433.1 CDS TBMG_03435 NC_012943.1 3794529 3795308 D transposase 3794529..3795308 Mycobacterium tuberculosis KZN 1435 8164337 YP_003033434.1 CDS TBMG_03436 NC_012943.1 3795235 3795975 D transposase 3795235..3795975 Mycobacterium tuberculosis KZN 1435 8164338 YP_003033435.1 CDS TBMG_04109 NC_012943.1 3796165 3798360 D PE-PGRS family protein 3796165..3798360 Mycobacterium tuberculosis KZN 1435 8164339 YP_003033436.1 CDS TBMG_03439 NC_012943.1 3798431 3799303 R dehydrogenase complement(3798431..3799303) Mycobacterium tuberculosis KZN 1435 8164340 YP_003033437.1 CDS TBMG_03440 NC_012943.1 3799377 3800087 D hypothetical protein 3799377..3800087 Mycobacterium tuberculosis KZN 1435 8164341 YP_003033438.1 CDS TBMG_03441 NC_012943.1 3800133 3802085 D short chain dehydrogenase 3800133..3802085 Mycobacterium tuberculosis KZN 1435 8164342 YP_003033439.1 CDS TBMG_03442 NC_012943.1 3802086 3802949 R cyclopropane-fatty-acyl-phospholipid synthase 1 cmaA1 complement(3802086..3802949) Mycobacterium tuberculosis KZN 1435 8164343 YP_003033440.1 CDS TBMG_03443 NC_012943.1 3802973 3803899 D nucleoside hydrolase iunH 3802973..3803899 Mycobacterium tuberculosis KZN 1435 8164344 YP_003033441.1 CDS TBMG_03444 NC_012943.1 3803954 3805537 R hypothetical protein complement(3803954..3805537) Mycobacterium tuberculosis KZN 1435 8164345 YP_003033442.1 CDS TBMG_03445 NC_012943.1 3805534 3806148 R hypothetical protein complement(3805534..3806148) Mycobacterium tuberculosis KZN 1435 8164346 YP_003033443.1 CDS TBMG_03446 NC_012943.1 3806147 3806857 D hypothetical protein 3806147..3806857 Mycobacterium tuberculosis KZN 1435 8164348 YP_003033444.1 CDS guaA NC_012943.1 3807013 3808590 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(3807013..3808590) Mycobacterium tuberculosis KZN 1435 8164347 YP_003033445.1 CDS TBMG_03448 NC_012943.1 3808602 3809510 R phytoene synthase complement(3808602..3809510) Mycobacterium tuberculosis KZN 1435 8164349 YP_003033446.1 CDS TBMG_03449 NC_012943.1 3809539 3810618 R multifunctional geranylgeranyl pyrophosphate synthetase idsA1 complement(3809539..3810618) Mycobacterium tuberculosis KZN 1435 8164350 YP_003033447.1 CDS TBMG_03450 NC_012943.1 3810641 3811687 D hypothetical protein 3810641..3811687 Mycobacterium tuberculosis KZN 1435 8164351 YP_003033448.1 CDS TBMG_03451 NC_012943.1 3811751 3812539 D hydrolase 3811751..3812539 Mycobacterium tuberculosis KZN 1435 8164352 YP_003033449.1 CDS TBMG_03452 NC_012943.1 3812554 3814914 D hypothetical protein 3812554..3814914 Mycobacterium tuberculosis KZN 1435 8164353 YP_003033450.1 CDS TBMG_03453 NC_012943.1 3815397 3816635 R hypothetical protein complement(3815397..3816635) Mycobacterium tuberculosis KZN 1435 8164354 YP_003033451.1 CDS TBMG_03454 NC_012943.1 3817006 3818607 R hypothetical protein complement(3817006..3818607) Mycobacterium tuberculosis KZN 1435 8164355 YP_003033452.1 CDS TBMG_03455 NC_012943.1 3818624 3819328 R hypothetical protein complement(3818624..3819328) Mycobacterium tuberculosis KZN 1435 8164356 YP_003033453.1 CDS TBMG_03456 NC_012943.1 3819446 3820012 R transcriptional regulator complement(3819446..3820012) Mycobacterium tuberculosis KZN 1435 8164357 YP_003033454.1 CDS TBMG_03457 NC_012943.1 3820074 3820961 D dioxygenase 3820074..3820961 Mycobacterium tuberculosis KZN 1435 8164358 YP_003033455.1 CDS TBMG_03458 NC_012943.1 3820996 3821295 D antitoxin 3820996..3821295 Mycobacterium tuberculosis KZN 1435 8164359 YP_003033456.1 CDS TBMG_03459 NC_012943.1 3821292 3821702 D toxin 3821292..3821702 Mycobacterium tuberculosis KZN 1435 8164360 YP_003033457.1 CDS TBMG_03460 NC_012943.1 3821735 3823471 R cholesterol oxidase precursor choD complement(3821735..3823471) Mycobacterium tuberculosis KZN 1435 8164361 YP_003033458.1 CDS TBMG_03461 NC_012943.1 3823527 3824654 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase complement(3823527..3824654) Mycobacterium tuberculosis KZN 1435 8164362 YP_003033459.1 CDS TBMG_03462 NC_012943.1 3824674 3826263 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(3824674..3826263) Mycobacterium tuberculosis KZN 1435 8164363 YP_003033460.1 CDS TBMG_03463 NC_012943.1 3826470 3826880 D hypothetical protein 3826470..3826880 Mycobacterium tuberculosis KZN 1435 8164364 YP_003033461.1 CDS TBMG_03464 NC_012943.1 3826890 3827789 R hypothetical protein complement(3826890..3827789) Mycobacterium tuberculosis KZN 1435 8164365 YP_003033462.1 CDS TBMG_03465 NC_012943.1 3827782 3828420 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase; RNA polymerase sigma factor SigD complement(3827782..3828420) Mycobacterium tuberculosis KZN 1435 8164366 YP_003033463.1 CDS TBMG_03466 NC_012943.1 3828378 3829229 R hypothetical protein complement(3828378..3829229) Mycobacterium tuberculosis KZN 1435 8164367 YP_003033464.1 CDS TBMG_03467 NC_012943.1 3829636 3829944 D transcriptional regulator whib-like whiB3 3829636..3829944 Mycobacterium tuberculosis KZN 1435 8164368 YP_003033465.1 CDS groEL NC_012943.1 3830016 3831635 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; molecular chaperone GroEL complement(3830016..3831635) Mycobacterium tuberculosis KZN 1435 8164369 YP_003033466.1 CDS groES NC_012943.1 3831730 3832032 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(3831730..3832032) Mycobacterium tuberculosis KZN 1435 8164370 YP_003033467.1 CDS TBMG_03470 NC_012943.1 3832299 3833333 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3832299..3833333) Mycobacterium tuberculosis KZN 1435 8164371 YP_003033468.1 CDS TBMG_03471 NC_012943.1 3833330 3833812 R ribosomal-protein-alanine acetyltransferase rimI complement(3833330..3833812) Mycobacterium tuberculosis KZN 1435 8164372 YP_003033469.1 CDS TBMG_03472 NC_012943.1 3833803 3834450 R hypothetical protein complement(3833803..3834450) Mycobacterium tuberculosis KZN 1435 8164373 YP_003033470.1 CDS TBMG_03473 NC_012943.1 3834435 3834941 R hypothetical protein complement(3834435..3834941) Mycobacterium tuberculosis KZN 1435 8164374 YP_003033471.1 CDS alr NC_012943.1 3834938 3836164 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(3834938..3836164) Mycobacterium tuberculosis KZN 1435 8164375 YP_003033472.1 CDS TBMG_03475 NC_012943.1 3836458 3836820 R hypothetical protein complement(3836458..3836820) Mycobacterium tuberculosis KZN 1435 8164376 YP_003033473.1 CDS TBMG_03476 NC_012943.1 3836983 3837519 D PPE family protein 3836983..3837519 Mycobacterium tuberculosis KZN 1435 8164377 YP_003033474.1 CDS TBMG_03477 NC_012943.1 3837460 3838623 R transposase complement(3837460..3838623) Mycobacterium tuberculosis KZN 1435 8164378 YP_003033475.1 CDS TBMG_04110 NC_012943.1 3838662 3838817 R hypothetical protein complement(3838662..3838817) Mycobacterium tuberculosis KZN 1435 8164379 YP_003033476.1 CDS TBMG_03478 NC_012943.1 3838842 3839051 R hypothetical protein complement(3838842..3839051) Mycobacterium tuberculosis KZN 1435 8164380 YP_003033477.1 CDS TBMG_03479 NC_012943.1 3839112 3839957 R transposase complement(3839112..3839957) Mycobacterium tuberculosis KZN 1435 8164381 YP_003033478.1 CDS TBMG_03480 NC_012943.1 3840190 3841572 R glutamate decarboxylase gadB complement(3840190..3841572) Mycobacterium tuberculosis KZN 1435 8164382 YP_003033479.1 CDS TBMG_03481 NC_012943.1 3841610 3843031 R hypothetical protein complement(3841610..3843031) Mycobacterium tuberculosis KZN 1435 8164383 YP_003033480.1 CDS TBMG_03482 NC_012943.1 3843033 3843746 R hypothetical protein complement(3843033..3843746) Mycobacterium tuberculosis KZN 1435 8164384 YP_003033481.1 CDS TBMG_03483 NC_012943.1 3843757 3844695 R hypothetical protein complement(3843757..3844695) Mycobacterium tuberculosis KZN 1435 8164385 YP_003033482.1 CDS TBMG_03484 NC_012943.1 3844833 3846707 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(3844833..3846707) Mycobacterium tuberculosis KZN 1435 8164386 YP_003033483.1 CDS TBMG_03485 NC_012943.1 3846729 3847205 D hypothetical protein 3846729..3847205 Mycobacterium tuberculosis KZN 1435 8164387 YP_003033484.1 CDS TBMG_03486 NC_012943.1 3847215 3848057 D hypothetical protein 3847215..3848057 Mycobacterium tuberculosis KZN 1435 8164388 YP_003033485.1 CDS TBMG_03487 NC_012943.1 3848077 3849480 R hypothetical protein complement(3848077..3849480) Mycobacterium tuberculosis KZN 1435 8164389 YP_003033486.1 CDS TBMG_03488 NC_012943.1 3849483 3849794 R hypothetical protein complement(3849483..3849794) Mycobacterium tuberculosis KZN 1435 8164390 YP_003033487.1 CDS glmM NC_012943.1 3849842 3851188 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3849842..3851188) Mycobacterium tuberculosis KZN 1435 8164391 YP_003033488.1 CDS rpsI NC_012943.1 3851313 3851768 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3851313..3851768) Mycobacterium tuberculosis KZN 1435 8164392 YP_003033489.1 CDS rplM NC_012943.1 3851765 3852208 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3851765..3852208) Mycobacterium tuberculosis KZN 1435 8164393 YP_003033490.1 CDS TBMG_03492 NC_012943.1 3852441 3852743 R esat-6 like protein esxT complement(3852441..3852743) Mycobacterium tuberculosis KZN 1435 8164394 YP_003033491.1 CDS TBMG_03493 NC_012943.1 3852764 3853141 R esat-6 like protein esxU complement(3852764..3853141) Mycobacterium tuberculosis KZN 1435 8164395 YP_003033492.1 CDS TBMG_03494 NC_012943.1 3853134 3854348 R hypothetical protein complement(3853134..3854348) Mycobacterium tuberculosis KZN 1435 8164396 YP_003033493.1 CDS TBMG_03495 NC_012943.1 3854345 3858055 R hypothetical protein complement(3854345..3858055) Mycobacterium tuberculosis KZN 1435 8164397 YP_003033494.1 CDS TBMG_03496 NC_012943.1 3858169 3859572 D hypothetical protein 3858169..3859572 Mycobacterium tuberculosis KZN 1435 8164398 YP_003033495.1 CDS TBMG_03497 NC_012943.1 3859569 3860936 D membrane-anchored mycosin mycP4 3859569..3860936 Mycobacterium tuberculosis KZN 1435 8164399 YP_003033496.1 CDS TBMG_03498 NC_012943.1 3860901 3862349 R hypothetical protein complement(3860901..3862349) Mycobacterium tuberculosis KZN 1435 8164400 YP_003033497.1 CDS TBMG_03499 NC_012943.1 3862434 3863222 D cutinase precursor cut3 3862434..3863222 Mycobacterium tuberculosis KZN 1435 8164401 YP_003033498.1 CDS TBMG_03500 NC_012943.1 3863254 3863949 D cutinase precursor cut4 3863254..3863949 Mycobacterium tuberculosis KZN 1435 8164402 YP_003033499.1 CDS TBMG_03501 NC_012943.1 3864221 3864553 D hypothetical protein 3864221..3864553 Mycobacterium tuberculosis KZN 1435 8164403 YP_003033500.1 CDS TBMG_03502 NC_012943.1 3864576 3865907 D hypothetical protein 3864576..3865907 Mycobacterium tuberculosis KZN 1435 8164321 YP_003033501.1 CDS truA NC_012943.1 3865869 3866762 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(3865869..3866762) Mycobacterium tuberculosis KZN 1435 8161731 YP_003033502.1 CDS rplQ NC_012943.1 3866707 3867249 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3866707..3867249) Mycobacterium tuberculosis KZN 1435 8161732 YP_003033503.1 CDS TBMG_03505 NC_012943.1 3867281 3868324 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3867281..3868324) Mycobacterium tuberculosis KZN 1435 8161733 YP_003033504.1 CDS rpsD NC_012943.1 3868476 3869081 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3868476..3869081) Mycobacterium tuberculosis KZN 1435 8161734 YP_003033505.1 CDS TBMG_03507 NC_012943.1 3869090 3869509 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3869090..3869509) Mycobacterium tuberculosis KZN 1435 8161735 YP_003033506.1 CDS rpsM NC_012943.1 3869513 3869887 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3869513..3869887) Mycobacterium tuberculosis KZN 1435 8161736 YP_003033507.1 CDS rpmJ NC_012943.1 3870103 3870216 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(3870103..3870216) Mycobacterium tuberculosis KZN 1435 8161737 YP_003033508.1 CDS infA NC_012943.1 3870249 3870470 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(3870249..3870470) Mycobacterium tuberculosis KZN 1435 8161738 YP_003033509.1 CDS TBMG_03511 NC_012943.1 3870724 3871581 D hypothetical protein 3870724..3871581 Mycobacterium tuberculosis KZN 1435 8161739 YP_003033510.1 CDS TBMG_03512 NC_012943.1 3871654 3872649 D dTDP-glucose 4,6-dehydratase rmlB 3871654..3872649 Mycobacterium tuberculosis KZN 1435 8161740 YP_003033511.1 CDS TBMG_03513 NC_012943.1 3872651 3873259 D dTDP-4-dehydrorhamnose 3,5-epimerase rmlC 3872651..3873259 Mycobacterium tuberculosis KZN 1435 8161741 YP_003033512.1 CDS TBMG_03514 NC_012943.1 3873342 3874010 D hypothetical protein 3873342..3874010 Mycobacterium tuberculosis KZN 1435 8161742 YP_003033513.1 CDS TBMG_03515 NC_012943.1 3873871 3874734 D hypothetical protein 3873871..3874734 Mycobacterium tuberculosis KZN 1435 8161743 YP_003033514.1 CDS TBMG_03516 NC_012943.1 3874792 3875886 R dTDP-glucose-4,6-dehydratase complement(3874792..3875886) Mycobacterium tuberculosis KZN 1435 8161744 YP_003033515.1 CDS TBMG_03517 NC_012943.1 3875890 3876900 R catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase complement(3875890..3876900) Mycobacterium tuberculosis KZN 1435 8161745 YP_003033516.1 CDS TBMG_03518 NC_012943.1 3876961 3878634 R acetolactate synthase large subunit ilvB2 complement(3876961..3878634) Mycobacterium tuberculosis KZN 1435 8161746 YP_003033517.1 CDS TBMG_03519 NC_012943.1 3878625 3879158 R hypothetical protein complement(3878625..3879158) Mycobacterium tuberculosis KZN 1435 8161747 YP_003033518.1 CDS TBMG_03520 NC_012943.1 3879179 3879685 D hypothetical protein 3879179..3879685 Mycobacterium tuberculosis KZN 1435 8161748 YP_003033519.1 CDS TBMG_03521 NC_012943.1 3879765 3880634 R peroxidase bpoA complement(3879765..3880634) Mycobacterium tuberculosis KZN 1435 8161749 YP_003033520.1 CDS TBMG_03522 NC_012943.1 3880830 3882179 R hypothetical protein complement(3880830..3882179) Mycobacterium tuberculosis KZN 1435 8161750 YP_003033521.1 CDS TBMG_03523 NC_012943.1 3882552 3882848 D PE family protein 3882552..3882848 Mycobacterium tuberculosis KZN 1435 8161751 YP_003033522.1 CDS TBMG_03524 NC_012943.1 3882885 3884066 D PPE family protein 3882885..3884066 Mycobacterium tuberculosis KZN 1435 8161752 YP_003033523.1 CDS TBMG_03525 NC_012943.1 3884096 3887344 D hypothetical protein 3884096..3887344 Mycobacterium tuberculosis KZN 1435 8161753 YP_003033524.1 CDS TBMG_03526 NC_012943.1 3887368 3888861 R hypothetical protein complement(3887368..3888861) Mycobacterium tuberculosis KZN 1435 8161754 YP_003033525.1 CDS TBMG_03527 NC_012943.1 3888952 3889698 R hypothetical protein complement(3888952..3889698) Mycobacterium tuberculosis KZN 1435 8161755 YP_003033526.1 CDS TBMG_03528 NC_012943.1 3889783 3890565 R hypothetical protein complement(3889783..3890565) Mycobacterium tuberculosis KZN 1435 8161756 YP_003033527.1 CDS TBMG_03529 NC_012943.1 3890609 3891271 R hypothetical protein complement(3890609..3891271) Mycobacterium tuberculosis KZN 1435 8161757 YP_003033528.1 CDS TBMG_03530 NC_012943.1 3891537 3893075 D hypothetical protein 3891537..3893075 Mycobacterium tuberculosis KZN 1435 8161758 YP_003033529.1 CDS TBMG_03531 NC_012943.1 3893081 3894025 R short chain dehydrogenase complement(3893081..3894025) Mycobacterium tuberculosis KZN 1435 8161759 YP_003033530.1 CDS TBMG_03532 NC_012943.1 3894231 3894680 D hypothetical protein 3894231..3894680 Mycobacterium tuberculosis KZN 1435 8161760 YP_003033531.1 CDS TBMG_03533 NC_012943.1 3894633 3895466 R esterase/lipase lipF complement(3894633..3895466) Mycobacterium tuberculosis KZN 1435 8161761 YP_003033532.1 CDS TBMG_03534 NC_012943.1 3896126 3896449 D hypothetical protein 3896126..3896449 Mycobacterium tuberculosis KZN 1435 8161762 YP_003033533.1 CDS TBMG_03535 NC_012943.1 3896695 3898197 D alpha, alpha-trehalose-phosphate synthase otsA 3896695..3898197 Mycobacterium tuberculosis KZN 1435 8161763 YP_003033534.1 CDS TBMG_03536 NC_012943.1 3898349 3898927 D hypothetical protein 3898349..3898927 Mycobacterium tuberculosis KZN 1435 8161764 YP_003033535.1 CDS TBMG_03537 NC_012943.1 3898924 3899406 R MCE-associated protein complement(3898924..3899406) Mycobacterium tuberculosis KZN 1435 8161765 YP_003033536.1 CDS TBMG_03538 NC_012943.1 3899406 3900134 R hypothetical protein complement(3899406..3900134) Mycobacterium tuberculosis KZN 1435 8161766 YP_003033537.1 CDS TBMG_03539 NC_012943.1 3900134 3901828 R MCE-family protein mce4F complement(3900134..3901828) Mycobacterium tuberculosis KZN 1435 8161767 YP_003033538.1 CDS TBMG_03540 NC_012943.1 3901839 3902993 R MCE-family lipoprotein mce4E complement(3901839..3902993) Mycobacterium tuberculosis KZN 1435 8161768 YP_003033539.1 CDS TBMG_03541 NC_012943.1 3902990 3904345 R MCE-family protein mce4D complement(3902990..3904345) Mycobacterium tuberculosis KZN 1435 8161769 YP_003033540.1 CDS TBMG_03542 NC_012943.1 3904342 3905415 R MCE-family protein mce4C complement(3904342..3905415) Mycobacterium tuberculosis KZN 1435 8161770 YP_003033541.1 CDS TBMG_03543 NC_012943.1 3905405 3906457 R MCE-family protein mce4B complement(3905405..3906457) Mycobacterium tuberculosis KZN 1435 8161771 YP_003033542.1 CDS TBMG_03544 NC_012943.1 3906457 3907659 R MCE-family protein mce4A complement(3906457..3907659) Mycobacterium tuberculosis KZN 1435 8161772 YP_003033543.1 CDS TBMG_03545 NC_012943.1 3907679 3908521 R hypothetical protein complement(3907679..3908521) Mycobacterium tuberculosis KZN 1435 8161773 YP_003033544.1 CDS TBMG_03546 NC_012943.1 3908556 3909320 R hypothetical protein complement(3908556..3909320) Mycobacterium tuberculosis KZN 1435 8161774 YP_003033545.1 CDS fabG NC_012943.1 3909546 3910499 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(3909546..3910499) Mycobacterium tuberculosis KZN 1435 8161775 YP_003033546.1 CDS TBMG_03548 NC_012943.1 3910524 3910715 R ferredoxin fdxD complement(3910524..3910715) Mycobacterium tuberculosis KZN 1435 8161776 YP_003033547.1 CDS TBMG_03549 NC_012943.1 3910930 3912132 D acyl-CoA dehydrogenase 3910930..3912132 Mycobacterium tuberculosis KZN 1435 8161777 YP_003033548.1 CDS TBMG_03550 NC_012943.1 3912157 3913278 D acyl-CoA dehydrogenase 3912157..3913278 Mycobacterium tuberculosis KZN 1435 8161778 YP_003033549.1 CDS TBMG_03551 NC_012943.1 3913349 3914857 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3913349..3914857 Mycobacterium tuberculosis KZN 1435 8161779 YP_003033550.1 CDS TBMG_03552 NC_012943.1 3915028 3919239 D PE-PGRS family protein 3915028..3919239 Mycobacterium tuberculosis KZN 1435 8161780 YP_003033551.1 CDS TBMG_04111 NC_012943.1 3919530 3923975 D hypothetical protein 3919530..3923975 Mycobacterium tuberculosis KZN 1435 8161781 YP_003033552.1 CDS TBMG_04112 NC_012943.1 3924142 3925689 R thiamine-pyrophosphate requiring enzyme; hypothetical protein complement(3924142..3925689) Mycobacterium tuberculosis KZN 1435 8161782 YP_003033553.1 CDS TBMG_04113 NC_012943.1 3925686 3926522 R hypothetical protein complement(3925686..3926522) Mycobacterium tuberculosis KZN 1435 8161783 YP_003033554.1 CDS TBMG_04114 NC_012943.1 3926882 3932185 D hypothetical protein 3926882..3932185 Mycobacterium tuberculosis KZN 1435 8161784 YP_003033555.1 CDS TBMG_04115 NC_012943.1 3932314 3932970 R fatty-acid-CoA ligase fadD18 complement(3932314..3932970) Mycobacterium tuberculosis KZN 1435 8161785 YP_003033556.1 CDS TBMG_03553 NC_012943.1 3933016 3935736 D hypothetical protein 3933016..3935736 Mycobacterium tuberculosis KZN 1435 8161786 YP_003033557.1 CDS TBMG_03554 NC_012943.1 3936297 3937943 R activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; acyl-CoA synthetase complement(3936297..3937943) Mycobacterium tuberculosis KZN 1435 8161787 YP_003033558.1 CDS TBMG_03555 NC_012943.1 3938017 3938808 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3938017..3938808 Mycobacterium tuberculosis KZN 1435 8161788 YP_003033559.1 CDS TBMG_03556 NC_012943.1 3938904 3939743 D hypothetical protein 3938904..3939743 Mycobacterium tuberculosis KZN 1435 8161789 YP_003033560.1 CDS TBMG_03557 NC_012943.1 3939798 3940994 R cytochrome P450 monooxygenase 142 cyp142 complement(3939798..3940994) Mycobacterium tuberculosis KZN 1435 8161790 YP_003033561.1 CDS TBMG_03558 NC_012943.1 3941023 3941733 D hypothetical protein 3941023..3941733 Mycobacterium tuberculosis KZN 1435 8161791 YP_003033562.1 CDS TBMG_03559 NC_012943.1 3941798 3942841 R coenzyme F420-dependent oxidoreductase complement(3941798..3942841) Mycobacterium tuberculosis KZN 1435 8161792 YP_003033563.1 CDS TBMG_03560 NC_012943.1 3942901 3943905 D hypothetical protein 3942901..3943905 Mycobacterium tuberculosis KZN 1435 8161793 YP_003033564.1 CDS TBMG_03561 NC_012943.1 3943921 3944985 D lipid-transfer protein 3943921..3944985 Mycobacterium tuberculosis KZN 1435 8161794 YP_003033565.1 CDS TBMG_03562 NC_012943.1 3945002 3946186 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3945002..3946186 Mycobacterium tuberculosis KZN 1435 8161795 YP_003033566.1 CDS TBMG_03563 NC_012943.1 3946228 3947259 D hypothetical protein 3946228..3947259 Mycobacterium tuberculosis KZN 1435 8161796 YP_003033567.1 CDS TBMG_03564 NC_012943.1 3947273 3947797 R siderophore-binding protein complement(3947273..3947797) Mycobacterium tuberculosis KZN 1435 8161797 YP_003033568.1 CDS TBMG_03565 NC_012943.1 3947912 3949072 D oxidoreductase 3947912..3949072 Mycobacterium tuberculosis KZN 1435 8161798 YP_003033569.1 CDS TBMG_03566 NC_012943.1 3949078 3949527 D hypothetical protein 3949078..3949527 Mycobacterium tuberculosis KZN 1435 8161799 YP_003033570.1 CDS TBMG_03567 NC_012943.1 3949952 3950665 R hypothetical protein complement(3949952..3950665) Mycobacterium tuberculosis KZN 1435 8161800 YP_003033571.1 CDS TBMG_03568 NC_012943.1 3951357 3952511 R hypothetical protein complement(3951357..3952511) Mycobacterium tuberculosis KZN 1435 8161801 YP_003033572.1 CDS TBMG_03569 NC_012943.1 3952511 3953293 R short chain dehydrogenase complement(3952511..3953293) Mycobacterium tuberculosis KZN 1435 8161802 YP_003033573.1 CDS TBMG_04116 NC_012943.1 3953290 3954417 R hypothetical protein complement(3953290..3954417) Mycobacterium tuberculosis KZN 1435 8161803 YP_003033574.1 CDS TBMG_03572 NC_012943.1 3954816 3956036 D PPE family protein 3954816..3956036 Mycobacterium tuberculosis KZN 1435 8161804 YP_003033575.1 CDS TBMG_03573 NC_012943.1 3956178 3957926 R PPE family protein complement(3956178..3957926) Mycobacterium tuberculosis KZN 1435 8161805 YP_003033576.1 CDS TBMG_03574 NC_012943.1 3958025 3959065 R catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase complement(3958025..3959065) Mycobacterium tuberculosis KZN 1435 8161806 YP_003033577.1 CDS TBMG_03575 NC_012943.1 3959062 3959973 R catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase complement(3959062..3959973) Mycobacterium tuberculosis KZN 1435 8161807 YP_003033578.1 CDS TBMG_03576 NC_012943.1 3959984 3960769 R hydratase complement(3959984..3960769) Mycobacterium tuberculosis KZN 1435 8161808 YP_003033579.1 CDS TBMG_03577 NC_012943.1 3960833 3962533 D initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 3960833..3962533 Mycobacterium tuberculosis KZN 1435 8161485 YP_003033580.1 CDS TBMG_03578 NC_012943.1 3962535 3963395 D dehydrogenase 3962535..3963395 Mycobacterium tuberculosis KZN 1435 8161568 YP_003033581.1 CDS TBMG_03579 NC_012943.1 3963532 3964971 D PPE family protein 3963532..3964971 Mycobacterium tuberculosis KZN 1435 8161569 YP_003033582.1 CDS TBMG_03580 NC_012943.1 3964972 3966132 R lipid-transfer protein complement(3964972..3966132) Mycobacterium tuberculosis KZN 1435 8161570 YP_003033583.1 CDS TBMG_03581 NC_012943.1 3966132 3966521 R hypothetical protein complement(3966132..3966521) Mycobacterium tuberculosis KZN 1435 8161571 YP_003033584.1 CDS TBMG_03582 NC_012943.1 3966518 3967453 R hypothetical protein complement(3966518..3967453) Mycobacterium tuberculosis KZN 1435 8161572 YP_003033585.1 CDS TBMG_03583 NC_012943.1 3967450 3968613 R acyl-CoA dehydrogenase complement(3967450..3968613) Mycobacterium tuberculosis KZN 1435 8161573 YP_003033586.1 CDS TBMG_04117 NC_012943.1 3968598 3969635 R acyl-CoA dehydrogenase complement(3968598..3969635) Mycobacterium tuberculosis KZN 1435 8161574 YP_003033587.1 CDS TBMG_03584 NC_012943.1 3969617 3970918 R cytochrome P450 125 cyp125 complement(3969617..3970918) Mycobacterium tuberculosis KZN 1435 8161575 YP_003033588.1 CDS TBMG_03585 NC_012943.1 3971030 3972205 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3971030..3972205 Mycobacterium tuberculosis KZN 1435 8161576 YP_003033589.1 CDS TBMG_03586 NC_012943.1 3972317 3972772 D hypothetical protein 3972317..3972772 Mycobacterium tuberculosis KZN 1435 8161577 YP_003033590.1 CDS TBMG_03587 NC_012943.1 3972855 3973769 R short chain dehydrogenase complement(3972855..3973769) Mycobacterium tuberculosis KZN 1435 8161578 YP_003033591.1 CDS TBMG_03588 NC_012943.1 3973792 3974571 R short chain dehydrogenase complement(3973792..3974571) Mycobacterium tuberculosis KZN 1435 8161579 YP_003033592.1 CDS TBMG_03589 NC_012943.1 3974626 3975369 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3974626..3975369 Mycobacterium tuberculosis KZN 1435 8161580 YP_003033593.1 CDS TBMG_03590 NC_012943.1 3975369 3976247 D CoA-transferase alpha subunit 3975369..3976247 Mycobacterium tuberculosis KZN 1435 8161581 YP_003033594.1 CDS TBMG_03591 NC_012943.1 3976244 3976996 D CoA-transferase beta subunit 3976244..3976996 Mycobacterium tuberculosis KZN 1435 8161582 YP_003033595.1 CDS TBMG_03592 NC_012943.1 3977094 3978161 D oxidoreductase 3977094..3978161 Mycobacterium tuberculosis KZN 1435 8161583 YP_003033596.1 CDS TBMG_03593 NC_012943.1 3978158 3980215 D electron transfer protein fdxB 3978158..3980215 Mycobacterium tuberculosis KZN 1435 8161584 YP_003033597.1 CDS TBMG_03594 NC_012943.1 3980303 3981172 R hypothetical protein complement(3980303..3981172) Mycobacterium tuberculosis KZN 1435 8161585 YP_003033598.1 CDS TBMG_03595 NC_012943.1 3981277 3982437 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(3981277..3982437) Mycobacterium tuberculosis KZN 1435 8161586 YP_003033599.1 CDS TBMG_03596 NC_012943.1 3982502 3983104 R TetR family transcriptional regulator complement(3982502..3983104) Mycobacterium tuberculosis KZN 1435 8161587 YP_003033600.1 CDS TBMG_03597 NC_012943.1 3983213 3985108 D PPE family protein 3983213..3985108 Mycobacterium tuberculosis KZN 1435 8161588 YP_003033601.1 CDS TBMG_03598 NC_012943.1 3985117 3985905 R short chain dehydrogenase complement(3985117..3985905) Mycobacterium tuberculosis KZN 1435 8161589 YP_003033602.1 CDS TBMG_03599 NC_012943.1 3985902 3987059 R acyl-CoA dehydrogenase complement(3985902..3987059) Mycobacterium tuberculosis KZN 1435 8161590 YP_003033603.1 CDS TBMG_03600 NC_012943.1 3987107 3988630 D activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 3987107..3988630 Mycobacterium tuberculosis KZN 1435 8161591 YP_003033604.1 CDS TBMG_03601 NC_012943.1 3988631 3989764 D acyl-CoA dehydrogenase 3988631..3989764 Mycobacterium tuberculosis KZN 1435 8161592 YP_003033605.1 CDS TBMG_03602 NC_012943.1 3989761 3990720 D acyl-CoA dehydrogenase 3989761..3990720 Mycobacterium tuberculosis KZN 1435 8161593 YP_003033606.1 CDS TBMG_03603 NC_012943.1 3990717 3991673 D acyl-CoA dehydrogenase 3990717..3991673 Mycobacterium tuberculosis KZN 1435 8161594 YP_003033607.1 CDS TBMG_03604 NC_012943.1 3991670 3992836 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 3991670..3992836 Mycobacterium tuberculosis KZN 1435 8161595 YP_003033608.1 CDS TBMG_03605 NC_012943.1 3992801 3994189 R arylamine N-acetyltransferase nat complement(3992801..3994189) Mycobacterium tuberculosis KZN 1435 8161596 YP_003033609.1 CDS TBMG_03606 NC_012943.1 3994189 3994752 R oxidoreductase complement(3994189..3994752) Mycobacterium tuberculosis KZN 1435 8161597 YP_003033610.1 CDS TBMG_03607 NC_012943.1 3994767 3995669 R biphenyl-2,3-diol 1,2-dioxygenase bphC complement(3994767..3995669) Mycobacterium tuberculosis KZN 1435 8161598 YP_003033611.1 CDS TBMG_03608 NC_012943.1 3995666 3996541 R 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase complement(3995666..3996541) Mycobacterium tuberculosis KZN 1435 8161599 YP_003033612.1 CDS TBMG_03609 NC_012943.1 3996556 3997740 R oxidoreductase complement(3996556..3997740) Mycobacterium tuberculosis KZN 1435 8161600 YP_003033613.1 CDS TBMG_03610 NC_012943.1 3997887 3998963 D hemoglobine-related protein hmp 3997887..3998963 Mycobacterium tuberculosis KZN 1435 8161601 YP_003033614.1 CDS TBMG_03611 NC_012943.1 3998981 3999511 D hypothetical protein 3998981..3999511 Mycobacterium tuberculosis KZN 1435 8161602 YP_003033615.1 CDS TBMG_03612 NC_012943.1 3999547 4001682 R acyl-CoA dehydrogenase complement(3999547..4001682) Mycobacterium tuberculosis KZN 1435 8161603 YP_003033616.1 CDS TBMG_03613 NC_012943.1 4001666 4002553 D TetR family transcriptional regulator 4001666..4002553 Mycobacterium tuberculosis KZN 1435 8161605 YP_003033617.1 CDS TBMG_03614 NC_012943.1 4002559 4003773 R transcriptional regulator, laci-family complement(4002559..4003773) Mycobacterium tuberculosis KZN 1435 8161604 YP_003033618.1 CDS TBMG_03615 NC_012943.1 4003828 4004541 D hypothetical protein 4003828..4004541 Mycobacterium tuberculosis KZN 1435 8161606 YP_003033619.1 CDS TBMG_03616 NC_012943.1 4004678 4005598 D hypothetical protein 4004678..4005598 Mycobacterium tuberculosis KZN 1435 8161607 YP_003033620.1 CDS TBMG_03617 NC_012943.1 4005612 4006853 D hypothetical protein 4005612..4006853 Mycobacterium tuberculosis KZN 1435 8161608 YP_003033621.1 CDS TBMG_03618 NC_012943.1 4006895 4007863 R tRNA/rRNA methyltransferase complement(4006895..4007863) Mycobacterium tuberculosis KZN 1435 8161609 YP_003033622.1 CDS cysS NC_012943.1 4007864 4009273 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(4007864..4009273) Mycobacterium tuberculosis KZN 1435 8161610 YP_003033623.1 CDS ispF NC_012943.1 4009338 4009817 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(4009338..4009817) Mycobacterium tuberculosis KZN 1435 8161611 YP_003033624.1 CDS ispD NC_012943.1 4009814 4010509 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(4009814..4010509) Mycobacterium tuberculosis KZN 1435 8161612 YP_003033625.1 CDS TBMG_03622 NC_012943.1 4010526 4011014 R transcriptional regulator complement(4010526..4011014) Mycobacterium tuberculosis KZN 1435 8161613 YP_003033626.1 CDS TBMG_03623 NC_012943.1 4011300 4011848 D hypothetical protein 4011300..4011848 Mycobacterium tuberculosis KZN 1435 8161614 YP_003033627.1 CDS TBMG_03624 NC_012943.1 4011914 4013356 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4011914..4013356 Mycobacterium tuberculosis KZN 1435 8161615 YP_003033628.1 CDS TBMG_03625 NC_012943.1 4013361 4014437 D non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 4013361..4014437 Mycobacterium tuberculosis KZN 1435 8161616 YP_003033629.1 CDS TBMG_03626 NC_012943.1 4014438 4015256 R hypothetical protein complement(4014438..4015256) Mycobacterium tuberculosis KZN 1435 8161617 YP_003033630.1 CDS TBMG_03627 NC_012943.1 4015341 4015964 R carbonic anhydrase complement(4015341..4015964) Mycobacterium tuberculosis KZN 1435 8161618 YP_003033631.1 CDS TBMG_03628 NC_012943.1 4015963 4016877 D adenine glycosylase mutY 4015963..4016877 Mycobacterium tuberculosis KZN 1435 8161620 YP_003033632.1 CDS TBMG_03629 NC_012943.1 4016874 4018628 R PE-PGRS family protein complement(4016874..4018628) Mycobacterium tuberculosis KZN 1435 8161619 YP_003033633.1 CDS TBMG_03630 NC_012943.1 4018739 4019512 R hydrolase complement(4018739..4019512) Mycobacterium tuberculosis KZN 1435 8161621 YP_003033634.1 CDS TBMG_03631 NC_012943.1 4019527 4019844 D hypothetical protein 4019527..4019844 Mycobacterium tuberculosis KZN 1435 8161622 YP_003033635.1 CDS TBMG_03632 NC_012943.1 4019822 4021180 D hypothetical protein 4019822..4021180 Mycobacterium tuberculosis KZN 1435 8161623 YP_003033636.1 CDS TBMG_03633 NC_012943.1 4021327 4022154 D hypothetical protein 4021327..4022154 Mycobacterium tuberculosis KZN 1435 8161624 YP_003033637.1 CDS TBMG_03634 NC_012943.1 4022201 4023520 R PE-PGRS family protein complement(4022201..4023520) Mycobacterium tuberculosis KZN 1435 8161625 YP_003033638.1 CDS TBMG_03635 NC_012943.1 4023628 4026174 R ATP-dependent protease ATP-binding subunit clpC1 complement(4023628..4026174) Mycobacterium tuberculosis KZN 1435 8161626 YP_003033639.1 CDS TBMG_03636 NC_012943.1 4026451 4026789 R iron-regulated lsr2 protein precursor complement(4026451..4026789) Mycobacterium tuberculosis KZN 1435 8161627 YP_003033640.1 CDS lysS NC_012943.1 4026893 4028410 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4026893..4028410) Mycobacterium tuberculosis KZN 1435 8161628 YP_003033641.1 CDS TBMG_03638 NC_012943.1 4028511 4029329 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(4028511..4029329) Mycobacterium tuberculosis KZN 1435 8161629 YP_003033642.1 CDS TBMG_03639 NC_012943.1 4029332 4029751 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(4029332..4029751) Mycobacterium tuberculosis KZN 1435 8161630 YP_003033643.1 CDS panC NC_012943.1 4029751 4030680 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(4029751..4030680) Mycobacterium tuberculosis KZN 1435 8161631 YP_003033644.1 CDS TBMG_03641 NC_012943.1 4030677 4031651 R hypothetical protein complement(4030677..4031651) Mycobacterium tuberculosis KZN 1435 8161632 YP_003033645.1 CDS TBMG_03642 NC_012943.1 4031773 4032966 R hypothetical protein complement(4031773..4032966) Mycobacterium tuberculosis KZN 1435 8161633 YP_003033646.1 CDS TBMG_03643 NC_012943.1 4033175 4033651 R hypothetical protein complement(4033175..4033651) Mycobacterium tuberculosis KZN 1435 8161634 YP_003033647.1 CDS TBMG_03644 NC_012943.1 4033651 4034217 R 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(4033651..4034217) Mycobacterium tuberculosis KZN 1435 8161635 YP_003033648.1 CDS TBMG_03645 NC_012943.1 4034214 4034615 R dihydroneopterin aldolase folB complement(4034214..4034615) Mycobacterium tuberculosis KZN 1435 8161636 YP_003033649.1 CDS TBMG_03646 NC_012943.1 4034608 4035450 R dihydropteroate synthase 1 folp complement(4034608..4035450) Mycobacterium tuberculosis KZN 1435 8161637 YP_003033650.1 CDS folE NC_012943.1 4035447 4036055 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(4035447..4036055) Mycobacterium tuberculosis KZN 1435 8161638 YP_003033651.1 CDS TBMG_03648 NC_012943.1 4036071 4038353 R membrane-bound ell division protein ftsH complement(4036071..4038353) Mycobacterium tuberculosis KZN 1435 8161639 YP_003033652.1 CDS TBMG_03650 NC_012943.1 4038877 4039206 R hypothetical protein complement(4038877..4039206) Mycobacterium tuberculosis KZN 1435 8161640 YP_003033653.1 CDS TBMG_03651 NC_012943.1 4039501 4040055 R hypothetical protein complement(4039501..4040055) Mycobacterium tuberculosis KZN 1435 8161641 YP_003033654.1 CDS TBMG_03652 NC_012943.1 4040171 4040482 R hypothetical protein complement(4040171..4040482) Mycobacterium tuberculosis KZN 1435 8161642 YP_003033655.1 CDS TBMG_03653 NC_012943.1 4040556 4041734 R hypothetical protein complement(4040556..4041734) Mycobacterium tuberculosis KZN 1435 8161643 YP_003033656.1 CDS TBMG_03654 NC_012943.1 4043092 4044060 D epoxide hydrolase ephA 4043092..4044060 Mycobacterium tuberculosis KZN 1435 8161644 YP_003033657.1 CDS TBMG_03655 NC_012943.1 4044057 4045244 D monooxygenase 4044057..4045244 Mycobacterium tuberculosis KZN 1435 8161645 YP_003033658.1 CDS TBMG_03656 NC_012943.1 4045343 4045627 R esat-6 like protein esxV complement(4045343..4045627) Mycobacterium tuberculosis KZN 1435 8161646 YP_003033659.1 CDS TBMG_03657 NC_012943.1 4045654 4045950 R esat-6 like protein esxW complement(4045654..4045950) Mycobacterium tuberculosis KZN 1435 8161647 YP_003033660.1 CDS TBMG_03658 NC_012943.1 4046007 4047248 R PPE family protein complement(4046007..4047248) Mycobacterium tuberculosis KZN 1435 8161648 YP_003033661.1 CDS TBMG_03659 NC_012943.1 4047258 4047557 R PE family protein complement(4047258..4047557) Mycobacterium tuberculosis KZN 1435 8163892 YP_003033662.1 CDS TBMG_03660 NC_012943.1 4047808 4048608 D hypothetical protein 4047808..4048608 Mycobacterium tuberculosis KZN 1435 8163893 YP_003033663.1 CDS TBMG_03661 NC_012943.1 4048613 4049263 R hypoxanthine-guanine phosphoribosyltransferase hpt complement(4048613..4049263) Mycobacterium tuberculosis KZN 1435 8163894 YP_003033664.1 CDS TBMG_03662 NC_012943.1 4049260 4050231 R cell cycle protein mesJ complement(4049260..4050231) Mycobacterium tuberculosis KZN 1435 8163895 YP_003033665.1 CDS TBMG_03663 NC_012943.1 4050210 4051271 R hypothetical protein complement(4050210..4051271) Mycobacterium tuberculosis KZN 1435 8163896 YP_003033666.1 CDS TBMG_03664 NC_012943.1 4051259 4052644 R hypothetical protein complement(4051259..4052644) Mycobacterium tuberculosis KZN 1435 8163897 YP_003033667.1 CDS TBMG_03665 NC_012943.1 4052782 4053270 D inorganic pyrophosphatase ppa 4052782..4053270 Mycobacterium tuberculosis KZN 1435 8163898 YP_003033668.1 CDS TBMG_03666 NC_012943.1 4053316 4054413 R hypothetical protein complement(4053316..4054413) Mycobacterium tuberculosis KZN 1435 8163899 YP_003033669.1 CDS TBMG_03667 NC_012943.1 4054534 4055829 D hypothetical protein 4054534..4055829 Mycobacterium tuberculosis KZN 1435 8163900 YP_003033670.1 CDS TBMG_03668 NC_012943.1 4055873 4056598 D transferase 4055873..4056598 Mycobacterium tuberculosis KZN 1435 8163901 YP_003033671.1 CDS TBMG_03669 NC_012943.1 4056595 4056939 D hypothetical protein 4056595..4056939 Mycobacterium tuberculosis KZN 1435 8163902 YP_003033672.1 CDS TBMG_03670 NC_012943.1 4057150 4058025 D hypothetical protein 4057150..4058025 Mycobacterium tuberculosis KZN 1435 8163903 YP_003033673.1 CDS TBMG_03671 NC_012943.1 4058026 4058994 R UDP-glucose 4-epimerase galE1 complement(4058026..4058994) Mycobacterium tuberculosis KZN 1435 8163904 YP_003033674.1 CDS TBMG_03672 NC_012943.1 4058993 4060768 D hypothetical protein 4058993..4060768 Mycobacterium tuberculosis KZN 1435 8163906 YP_003033675.1 CDS TBMG_03673 NC_012943.1 4061111 4061458 D transposase 4061111..4061458 Mycobacterium tuberculosis KZN 1435 8163905 YP_003033676.1 CDS TBMG_03674 NC_012943.1 4061843 4062343 D transposase 4061843..4062343 Mycobacterium tuberculosis KZN 1435 8163907 YP_003033677.1 CDS TBMG_03675 NC_012943.1 4062343 4063089 D transposase 4062343..4063089 Mycobacterium tuberculosis KZN 1435 8163908 YP_003033678.1 CDS TBMG_03676 NC_012943.1 4063263 4064147 R transposase complement(4063263..4064147) Mycobacterium tuberculosis KZN 1435 8163909 YP_003033679.1 CDS TBMG_03677 NC_012943.1 4064198 4064524 R transposase complement(4064198..4064524) Mycobacterium tuberculosis KZN 1435 8163910 YP_003033680.1 CDS TBMG_03678 NC_012943.1 4064601 4065167 R hypothetical protein complement(4064601..4065167) Mycobacterium tuberculosis KZN 1435 8163911 YP_003033681.1 CDS TBMG_03679 NC_012943.1 4065237 4066466 R transposase complement(4065237..4066466) Mycobacterium tuberculosis KZN 1435 8163912 YP_003033682.1 CDS TBMG_03680 NC_012943.1 4066642 4067277 R cell filamentation protein fic complement(4066642..4067277) Mycobacterium tuberculosis KZN 1435 8163913 YP_003033683.1 CDS TBMG_03681 NC_012943.1 4067288 4067482 R hypothetical protein complement(4067288..4067482) Mycobacterium tuberculosis KZN 1435 8163914 YP_003033684.1 CDS TBMG_03682 NC_012943.1 4067877 4068068 D hypothetical protein 4067877..4068068 Mycobacterium tuberculosis KZN 1435 8163915 YP_003033685.1 CDS TBMG_03683 NC_012943.1 4068233 4069441 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(4068233..4069441) Mycobacterium tuberculosis KZN 1435 8163917 YP_003033686.1 CDS TBMG_03684 NC_012943.1 4069524 4071173 D hypothetical protein 4069524..4071173 Mycobacterium tuberculosis KZN 1435 8161400 YP_003033687.1 CDS TBMG_03685 NC_012943.1 4071170 4073974 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(4071170..4073974) Mycobacterium tuberculosis KZN 1435 8161401 YP_003033688.1 CDS TBMG_03686 NC_012943.1 4074327 4074905 R hypothetical protein complement(4074327..4074905) Mycobacterium tuberculosis KZN 1435 8164496 YP_003033689.1 CDS TBMG_03687 NC_012943.1 4075045 4075248 R cold shock protein A cspA complement(4075045..4075248) Mycobacterium tuberculosis KZN 1435 8164497 YP_003033690.1 CDS TBMG_03688 NC_012943.1 4075498 4077813 D helicase 4075498..4077813 Mycobacterium tuberculosis KZN 1435 8164498 YP_003033691.1 CDS TBMG_03689 NC_012943.1 4077950 4078234 D PE family protein 4077950..4078234 Mycobacterium tuberculosis KZN 1435 8164499 YP_003033692.1 CDS TBMG_03690 NC_012943.1 4078558 4079595 D hypothetical protein 4078558..4079595 Mycobacterium tuberculosis KZN 1435 8164500 YP_003033693.1 CDS TBMG_03691 NC_012943.1 4080110 4080355 R hypothetical protein complement(4080110..4080355) Mycobacterium tuberculosis KZN 1435 8164501 YP_003033694.1 CDS TBMG_03692 NC_012943.1 4080342 4080662 D PE-PGRS family protein 4080342..4080662 Mycobacterium tuberculosis KZN 1435 8164503 YP_003033695.1 CDS TBMG_03693 NC_012943.1 4080656 4081243 D PE-PGRS family protein 4080656..4081243 Mycobacterium tuberculosis KZN 1435 8164502 YP_003033696.1 CDS TBMG_03694 NC_012943.1 4081376 4081699 R hypothetical protein complement(4081376..4081699) Mycobacterium tuberculosis KZN 1435 8164504 YP_003033697.1 CDS TBMG_03695 NC_012943.1 4081716 4082015 R hypothetical protein complement(4081716..4082015) Mycobacterium tuberculosis KZN 1435 8164505 YP_003033698.1 CDS TBMG_03696 NC_012943.1 4082039 4082245 R hypothetical protein complement(4082039..4082245) Mycobacterium tuberculosis KZN 1435 8164506 YP_003033699.1 CDS TBMG_03697 NC_012943.1 4082255 4082830 R hypothetical protein complement(4082255..4082830) Mycobacterium tuberculosis KZN 1435 8164507 YP_003033700.1 CDS TBMG_03698 NC_012943.1 4082854 4083654 R hypothetical protein complement(4082854..4083654) Mycobacterium tuberculosis KZN 1435 8164508 YP_003033701.1 CDS TBMG_03699 NC_012943.1 4083651 4084814 R hypothetical protein complement(4083651..4084814) Mycobacterium tuberculosis KZN 1435 8164509 YP_003033702.1 CDS TBMG_03700 NC_012943.1 4084811 4085884 R hypothetical protein complement(4084811..4085884) Mycobacterium tuberculosis KZN 1435 8164510 YP_003033703.1 CDS TBMG_03701 NC_012943.1 4086362 4087225 D hypothetical protein 4086362..4087225 Mycobacterium tuberculosis KZN 1435 8164511 YP_003033704.1 CDS TBMG_03702 NC_012943.1 4087980 4088750 R hypothetical protein complement(4087980..4088750) Mycobacterium tuberculosis KZN 1435 8164512 YP_003033705.1 CDS TBMG_03703 NC_012943.1 4088747 4090393 R dipeptide-transport ATP-binding protein ABC transporter dppD complement(4088747..4090393) Mycobacterium tuberculosis KZN 1435 8164513 YP_003033706.1 CDS TBMG_03704 NC_012943.1 4090390 4091253 R hypothetical protein complement(4090390..4091253) Mycobacterium tuberculosis KZN 1435 8164514 YP_003033707.1 CDS TBMG_03705 NC_012943.1 4091246 4092172 R hypothetical protein complement(4091246..4092172) Mycobacterium tuberculosis KZN 1435 8164515 YP_003033708.1 CDS TBMG_03706 NC_012943.1 4092174 4093799 R periplasmic dipeptide-binding lipoprotein dppA complement(4092174..4093799) Mycobacterium tuberculosis KZN 1435 8164516 YP_003033709.1 CDS TBMG_03707 NC_012943.1 4093885 4094241 D hypothetical protein 4093885..4094241 Mycobacterium tuberculosis KZN 1435 8164517 YP_003033710.1 CDS TBMG_03708 NC_012943.1 4094190 4094384 D hypothetical protein 4094190..4094384 Mycobacterium tuberculosis KZN 1435 8164518 YP_003033711.1 CDS TBMG_03709 NC_012943.1 4094507 4096462 D Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4094507..4096462 Mycobacterium tuberculosis KZN 1435 8164519 YP_003033712.1 CDS TBMG_03710 NC_012943.1 4096498 4097196 R protease complement(4096498..4097196) Mycobacterium tuberculosis KZN 1435 8164520 YP_003033713.1 CDS TBMG_03711 NC_012943.1 4097542 4098060 D hypothetical protein 4097542..4098060 Mycobacterium tuberculosis KZN 1435 8164521 YP_003033714.1 CDS TBMG_03712 NC_012943.1 4098061 4099044 D epoxide hydrolase ephE 4098061..4099044 Mycobacterium tuberculosis KZN 1435 8161402 YP_003033715.1 CDS TBMG_03713 NC_012943.1 4099037 4100230 R membrane-associated serine protease complement(4099037..4100230) Mycobacterium tuberculosis KZN 1435 8164523 YP_003033716.1 CDS TBMG_03714 NC_012943.1 4100236 4101057 R hypothetical protein complement(4100236..4101057) Mycobacterium tuberculosis KZN 1435 8164524 YP_003033717.1 CDS TBMG_03715 NC_012943.1 4101189 4101872 R membrane-anchored thioredoxin complement(4101189..4101872) Mycobacterium tuberculosis KZN 1435 8164525 YP_003033718.1 CDS TBMG_03716 NC_012943.1 4101872 4102609 R endonuclease III nth complement(4101872..4102609) Mycobacterium tuberculosis KZN 1435 8164526 YP_003033719.1 CDS TBMG_03717 NC_012943.1 4102717 4103094 D hypothetical protein 4102717..4103094 Mycobacterium tuberculosis KZN 1435 8164527 YP_003033720.1 CDS TBMG_03718 NC_012943.1 4103193 4103867 D transcriptional regulator, crp/fnr-family 4103193..4103867 Mycobacterium tuberculosis KZN 1435 8164528 YP_003033721.1 CDS TBMG_03719 NC_012943.1 4103973 4104767 R hydrolase complement(4103973..4104767) Mycobacterium tuberculosis KZN 1435 8164529 YP_003033722.1 CDS TBMG_03720 NC_012943.1 4104774 4105229 R hypothetical protein complement(4104774..4105229) Mycobacterium tuberculosis KZN 1435 8164530 YP_003033723.1 CDS TBMG_04118 NC_012943.1 4105245 4105406 R hypothetical protein complement(4105245..4105406) Mycobacterium tuberculosis KZN 1435 8164531 YP_003033724.1 CDS TBMG_03721 NC_012943.1 4105491 4106513 D anion transporter ATPase 4105491..4106513 Mycobacterium tuberculosis KZN 1435 8164532 YP_003033725.1 CDS TBMG_03722 NC_012943.1 4106510 4107670 D anion transporter ATPase 4106510..4107670 Mycobacterium tuberculosis KZN 1435 8164533 YP_003033726.1 CDS TBMG_03723 NC_012943.1 4108084 4108440 R transcriptional regulator whib-like whiB4 complement(4108084..4108440) Mycobacterium tuberculosis KZN 1435 8164534 YP_003033727.1 CDS TBMG_03724 NC_012943.1 4108802 4111234 D bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2 4108802..4111234 Mycobacterium tuberculosis KZN 1435 8164535 YP_003033728.1 CDS TBMG_03725 NC_012943.1 4111303 4112262 D hypothetical protein 4111303..4112262 Mycobacterium tuberculosis KZN 1435 8164536 YP_003033729.1 CDS TBMG_03726 NC_012943.1 4112259 4113365 D lyase 4112259..4113365 Mycobacterium tuberculosis KZN 1435 8164537 YP_003033730.1 CDS TBMG_03727 NC_012943.1 4114181 4115611 R cytochrome P450 137 cyp137 complement(4114181..4115611) Mycobacterium tuberculosis KZN 1435 8164539 YP_003033731.1 CDS TBMG_03728 NC_012943.1 4115637 4116086 R hypothetical protein complement(4115637..4116086) Mycobacterium tuberculosis KZN 1435 8164540 YP_003033732.1 CDS TBMG_03729 NC_012943.1 4116209 4116577 R anti-anti-sigma factor rsfB complement(4116209..4116577) Mycobacterium tuberculosis KZN 1435 8164541 YP_003033733.1 CDS TBMG_03730 NC_012943.1 4116779 4117243 R hypothetical protein complement(4116779..4117243) Mycobacterium tuberculosis KZN 1435 8164542 YP_003033734.1 CDS TBMG_03731 NC_012943.1 4117243 4118598 D hypothetical protein 4117243..4118598 Mycobacterium tuberculosis KZN 1435 8164544 YP_003033735.1 CDS TBMG_03732 NC_012943.1 4118577 4119278 D hypothetical protein 4118577..4119278 Mycobacterium tuberculosis KZN 1435 8164543 YP_003033736.1 CDS TBMG_03733 NC_012943.1 4119275 4120405 D hypothetical protein 4119275..4120405 Mycobacterium tuberculosis KZN 1435 8164545 YP_003033737.1 CDS TBMG_03734 NC_012943.1 4120402 4121478 D methanol dehydrogenase transcriptional regulator moxR2 4120402..4121478 Mycobacterium tuberculosis KZN 1435 8164546 YP_003033738.1 CDS TBMG_03735 NC_012943.1 4121570 4122934 D hypothetical protein 4121570..4122934 Mycobacterium tuberculosis KZN 1435 8164547 YP_003033739.1 CDS TBMG_03736 NC_012943.1 4123008 4124000 R hypothetical protein complement(4123008..4124000) Mycobacterium tuberculosis KZN 1435 8164548 YP_003033740.1 CDS TBMG_03737 NC_012943.1 4124092 4125024 D hypothetical protein 4124092..4125024 Mycobacterium tuberculosis KZN 1435 8164549 YP_003033741.1 CDS glpK NC_012943.1 4125088 4126641 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4125088..4126641) Mycobacterium tuberculosis KZN 1435 8164550 YP_003033742.1 CDS TBMG_03739 NC_012943.1 4126691 4127128 R toxin complement(4126691..4127128) Mycobacterium tuberculosis KZN 1435 8164551 YP_003033743.1 CDS TBMG_03740 NC_012943.1 4127125 4127349 R antitoxin complement(4127125..4127349) Mycobacterium tuberculosis KZN 1435 8164552 YP_003033744.1 CDS TBMG_03741 NC_012943.1 4127379 4128908 D hypothetical protein 4127379..4128908 Mycobacterium tuberculosis KZN 1435 8164553 YP_003033745.1 CDS TBMG_03742 NC_012943.1 4128930 4129631 D hypothetical protein 4128930..4129631 Mycobacterium tuberculosis KZN 1435 8164554 YP_003033746.1 CDS TBMG_03743 NC_012943.1 4129634 4130821 R hypothetical protein complement(4129634..4130821) Mycobacterium tuberculosis KZN 1435 8164555 YP_003033747.1 CDS TBMG_03744 NC_012943.1 4130837 4131802 R methyltransferase complement(4130837..4131802) Mycobacterium tuberculosis KZN 1435 8164556 YP_003033748.1 CDS TBMG_03745 NC_012943.1 4131799 4132500 R hypothetical protein complement(4131799..4132500) Mycobacterium tuberculosis KZN 1435 8164557 YP_003033749.1 CDS TBMG_03746 NC_012943.1 4132500 4133777 R hypothetical protein complement(4132500..4133777) Mycobacterium tuberculosis KZN 1435 8164558 YP_003033750.1 CDS TBMG_03747 NC_012943.1 4133774 4135072 R glutamate-cysteine ligase gshA complement(4133774..4135072) Mycobacterium tuberculosis KZN 1435 8164559 YP_003033751.1 CDS TBMG_03748 NC_012943.1 4135204 4135848 R hypothetical protein complement(4135204..4135848) Mycobacterium tuberculosis KZN 1435 8164560 YP_003033752.1 CDS TBMG_03749 NC_012943.1 4135977 4136366 R hypothetical protein complement(4135977..4136366) Mycobacterium tuberculosis KZN 1435 8164561 YP_003033753.1 CDS TBMG_03750 NC_012943.1 4136477 4136797 R hypothetical protein complement(4136477..4136797) Mycobacterium tuberculosis KZN 1435 8164562 YP_003033754.1 CDS TBMG_03751 NC_012943.1 4136916 4138022 R hypothetical protein complement(4136916..4138022) Mycobacterium tuberculosis KZN 1435 8164563 YP_003033755.1 CDS TBMG_03752 NC_012943.1 4138066 4139103 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(4138066..4139103) Mycobacterium tuberculosis KZN 1435 8164564 YP_003033756.1 CDS TBMG_03753 NC_012943.1 4139104 4140369 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(4139104..4140369) Mycobacterium tuberculosis KZN 1435 8164565 YP_003033757.1 CDS TBMG_03754 NC_012943.1 4140626 4142560 D 2-isopropylmalate synthase 4140626..4142560 Mycobacterium tuberculosis KZN 1435 8164566 YP_003033758.1 CDS TBMG_03755 NC_012943.1 4142626 4143615 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(4142626..4143615) Mycobacterium tuberculosis KZN 1435 8164567 YP_003033759.1 CDS TBMG_03756 NC_012943.1 4143926 4145167 D ligase 4143926..4145167 Mycobacterium tuberculosis KZN 1435 8164568 YP_003033760.1 CDS TBMG_03757 NC_012943.1 4145160 4145867 D cobyric acid synthase cobQ2 4145160..4145867 Mycobacterium tuberculosis KZN 1435 8164569 YP_003033761.1 CDS TBMG_03758 NC_012943.1 4145876 4146766 R hypothetical protein complement(4145876..4146766) Mycobacterium tuberculosis KZN 1435 8164570 YP_003033762.1 CDS recR NC_012943.1 4146834 4147445 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(4146834..4147445) Mycobacterium tuberculosis KZN 1435 8164571 YP_003033763.1 CDS TBMG_03760 NC_012943.1 4147457 4147858 R hypothetical protein complement(4147457..4147858) Mycobacterium tuberculosis KZN 1435 8164572 YP_003033764.1 CDS TBMG_03761 NC_012943.1 4147993 4148718 D hypothetical protein 4147993..4148718 Mycobacterium tuberculosis KZN 1435 8164573 YP_003033765.1 CDS TBMG_03762 NC_012943.1 4148760 4149203 R hypothetical protein complement(4148760..4149203) Mycobacterium tuberculosis KZN 1435 8164574 YP_003033766.1 CDS TBMG_03763 NC_012943.1 4149251 4150663 D hypothetical protein 4149251..4150663 Mycobacterium tuberculosis KZN 1435 8164575 YP_003033767.1 CDS TBMG_03764 NC_012943.1 4150660 4151943 D fatty-acid synthase 4150660..4151943 Mycobacterium tuberculosis KZN 1435 8164576 YP_003033768.1 CDS TBMG_03765 NC_012943.1 4151940 4153676 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(4151940..4153676) Mycobacterium tuberculosis KZN 1435 8164577 YP_003033769.1 CDS TBMG_03766 NC_012943.1 4153766 4155073 R hypothetical protein complement(4153766..4155073) Mycobacterium tuberculosis KZN 1435 8164578 YP_003033770.1 CDS TBMG_03767 NC_012943.1 4155481 4156245 D hypothetical protein 4155481..4156245 Mycobacterium tuberculosis KZN 1435 8164580 YP_003033771.1 CDS TBMG_03768 NC_012943.1 4156412 4156654 D cutinase cut5a 4156412..4156654 Mycobacterium tuberculosis KZN 1435 8164581 YP_003033772.1 CDS TBMG_03769 NC_012943.1 4156491 4157114 D cutinase cut5b 4156491..4157114 Mycobacterium tuberculosis KZN 1435 8164582 YP_003033773.1 CDS TBMG_03770 NC_012943.1 4157159 4158088 D oxidoreductase 4157159..4158088 Mycobacterium tuberculosis KZN 1435 8164583 YP_003033774.1 CDS TBMG_03771 NC_012943.1 4158366 4159559 D dehydrogenase 4158366..4159559 Mycobacterium tuberculosis KZN 1435 8164584 YP_003033775.1 CDS TBMG_03772 NC_012943.1 4159900 4161708 D oxidoreductase 4159900..4161708 Mycobacterium tuberculosis KZN 1435 8164585 YP_003033776.1 CDS TBMG_03773 NC_012943.1 4161818 4165015 D hypothetical protein 4161818..4165015 Mycobacterium tuberculosis KZN 1435 8164586 YP_003033777.1 CDS TBMG_03774 NC_012943.1 4165194 4167560 D transferase 4165194..4167560 Mycobacterium tuberculosis KZN 1435 8164587 YP_003033778.1 CDS TBMG_03775 NC_012943.1 4167625 4168665 R hypothetical protein complement(4167625..4168665) Mycobacterium tuberculosis KZN 1435 8164588 YP_003033779.1 CDS ligC NC_012943.1 4168703 4169779 D catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; ATP-dependent DNA ligase 4168703..4169779 Mycobacterium tuberculosis KZN 1435 8164589 YP_003033780.1 CDS TBMG_03777 NC_012943.1 4169879 4170937 D hypothetical protein 4169879..4170937 Mycobacterium tuberculosis KZN 1435 8164590 YP_003033781.1 CDS TBMG_03778 NC_012943.1 4170982 4171458 R hypothetical protein complement(4170982..4171458) Mycobacterium tuberculosis KZN 1435 8164591 YP_003033782.1 CDS TBMG_03779 NC_012943.1 4171472 4172836 R hypothetical protein complement(4171472..4172836) Mycobacterium tuberculosis KZN 1435 8164592 YP_003033783.1 CDS TBMG_03780 NC_012943.1 4173035 4173523 D hypothetical protein 4173035..4173523 Mycobacterium tuberculosis KZN 1435 8164593 YP_003033784.1 CDS TBMG_03781 NC_012943.1 4173580 4174641 D AraC family transcriptional regulator 4173580..4174641 Mycobacterium tuberculosis KZN 1435 8164594 YP_003033785.1 CDS TBMG_03782 NC_012943.1 4174645 4176234 D hypothetical protein 4174645..4176234 Mycobacterium tuberculosis KZN 1435 8164595 YP_003033786.1 CDS TBMG_03783 NC_012943.1 4176231 4177178 R PPE family protein complement(4176231..4177178) Mycobacterium tuberculosis KZN 1435 8164596 YP_003033787.1 CDS TBMG_03784 NC_012943.1 4177230 4177463 R PPE family protein complement(4177230..4177463) Mycobacterium tuberculosis KZN 1435 8164597 YP_003033788.1 CDS TBMG_03785 NC_012943.1 4177779 4179125 R hypothetical protein complement(4177779..4179125) Mycobacterium tuberculosis KZN 1435 8164598 YP_003033789.1 CDS TBMG_03786 NC_012943.1 4179125 4179799 R oxidoreductase complement(4179125..4179799) Mycobacterium tuberculosis KZN 1435 8164599 YP_003033790.1 CDS TBMG_03787 NC_012943.1 4179796 4180191 R oxidoreductase complement(4179796..4180191) Mycobacterium tuberculosis KZN 1435 8164600 YP_003033791.1 CDS TBMG_03788 NC_012943.1 4180337 4182319 R cation transporter P-type ATPase ctpJ complement(4180337..4182319) Mycobacterium tuberculosis KZN 1435 8164601 YP_003033792.1 CDS TBMG_03789 NC_012943.1 4182341 4182748 D transcriptional regulator, arsR-family 4182341..4182748 Mycobacterium tuberculosis KZN 1435 8164602 YP_003033793.1 CDS TBMG_03790 NC_012943.1 4182832 4183044 R hypothetical protein complement(4182832..4183044) Mycobacterium tuberculosis KZN 1435 8164603 YP_003033794.1 CDS TBMG_03791 NC_012943.1 4183117 4183452 R PE family protein complement(4183117..4183452) Mycobacterium tuberculosis KZN 1435 8163706 YP_003033795.1 CDS TBMG_03792 NC_012943.1 4183670 4184053 D hypothetical protein 4183670..4184053 Mycobacterium tuberculosis KZN 1435 8163811 YP_003033796.1 CDS TBMG_03793 NC_012943.1 4184183 4184542 D hypothetical protein 4184183..4184542 Mycobacterium tuberculosis KZN 1435 8163812 YP_003033797.1 CDS TBMG_03794 NC_012943.1 4184575 4185084 R hypothetical protein complement(4184575..4185084) Mycobacterium tuberculosis KZN 1435 8163813 YP_003033798.1 CDS TBMG_03795 NC_012943.1 4185152 4185544 R excisionase complement(4185152..4185544) Mycobacterium tuberculosis KZN 1435 8163814 YP_003033799.1 CDS TBMG_03796 NC_012943.1 4185820 4186035 D integrase 4185820..4186035 Mycobacterium tuberculosis KZN 1435 8163815 YP_003033800.1 CDS TBMG_03797 NC_012943.1 4186193 4186651 R cytidine/deoxycytidylate deaminase complement(4186193..4186651) Mycobacterium tuberculosis KZN 1435 8163817 YP_003033801.1 CDS TBMG_03798 NC_012943.1 4186667 4187188 R hypothetical protein complement(4186667..4187188) Mycobacterium tuberculosis KZN 1435 8163818 YP_003033802.1 CDS TBMG_03799 NC_012943.1 4187301 4188272 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 4187301..4188272 Mycobacterium tuberculosis KZN 1435 8163819 YP_003033803.1 CDS TBMG_03800 NC_012943.1 4188235 4188834 R hypothetical protein complement(4188235..4188834) Mycobacterium tuberculosis KZN 1435 8163820 YP_003033804.1 CDS TBMG_03801 NC_012943.1 4188840 4189559 R osmoprotectant proZ complement(4188840..4189559) Mycobacterium tuberculosis KZN 1435 8163821 YP_003033805.1 CDS TBMG_03802 NC_012943.1 4189556 4190245 R osmoprotectant proW complement(4189556..4190245) Mycobacterium tuberculosis KZN 1435 8163822 YP_003033806.1 CDS TBMG_03803 NC_012943.1 4190233 4191363 R osmoprotectant proV complement(4190233..4191363) Mycobacterium tuberculosis KZN 1435 8163823 YP_003033807.1 CDS TBMG_03804 NC_012943.1 4191372 4192319 R osmoprotectant proX complement(4191372..4192319) Mycobacterium tuberculosis KZN 1435 8163824 YP_003033808.1 CDS TBMG_03805 NC_012943.1 4192433 4192786 D hypothetical protein 4192433..4192786 Mycobacterium tuberculosis KZN 1435 8163825 YP_003033809.1 CDS TBMG_03806 NC_012943.1 4192808 4193863 R acyl-CoA dehydrogenase complement(4192808..4193863) Mycobacterium tuberculosis KZN 1435 8163826 YP_003033810.1 CDS TBMG_03807 NC_012943.1 4193942 4195822 R hydrolase complement(4193942..4195822) Mycobacterium tuberculosis KZN 1435 8163827 YP_003033811.1 CDS TBMG_03808 NC_012943.1 4195993 4196472 D 19 kDa lipoprotein antigen precursor lpqH 4195993..4196472 Mycobacterium tuberculosis KZN 1435 8163828 YP_003033812.1 CDS TBMG_03809 NC_012943.1 4196528 4198048 R two component system sensor kinase complement(4196528..4198048) Mycobacterium tuberculosis KZN 1435 8163829 YP_003033813.1 CDS TBMG_03810 NC_012943.1 4198026 4198886 R two component system transcriptional regulator complement(4198026..4198886) Mycobacterium tuberculosis KZN 1435 8163830 YP_003033814.1 CDS TBMG_03811 NC_012943.1 4199149 4199928 D hypothetical protein 4199149..4199928 Mycobacterium tuberculosis KZN 1435 8163831 YP_003033815.1 CDS TBMG_03812 NC_012943.1 4199942 4200886 R hypothetical protein complement(4199942..4200886) Mycobacterium tuberculosis KZN 1435 8163832 YP_003033816.1 CDS TBMG_03813 NC_012943.1 4201016 4201375 D hypothetical protein 4201016..4201375 Mycobacterium tuberculosis KZN 1435 8163833 YP_003033817.1 CDS TBMG_03814 NC_012943.1 4201561 4201833 D hypothetical protein 4201561..4201833 Mycobacterium tuberculosis KZN 1435 8163834 YP_003033818.1 CDS TBMG_03815 NC_012943.1 4202146 4202721 R hypothetical protein complement(4202146..4202721) Mycobacterium tuberculosis KZN 1435 8163835 YP_003033819.1 CDS TBMG_03816 NC_012943.1 4202827 4203009 R transposase complement(4202827..4203009) Mycobacterium tuberculosis KZN 1435 8163836 YP_003033820.1 CDS TBMG_03817 NC_012943.1 4203024 4203215 R transposase complement(4203024..4203215) Mycobacterium tuberculosis KZN 1435 8163837 YP_003033821.1 CDS TBMG_03818 NC_012943.1 4203350 4203676 R hypothetical protein complement(4203350..4203676) Mycobacterium tuberculosis KZN 1435 8163838 YP_003033822.1 CDS TBMG_03819 NC_012943.1 4204080 4205141 D aminotransferase 4204080..4205141 Mycobacterium tuberculosis KZN 1435 8163841 YP_003033823.1 CDS TBMG_03820 NC_012943.1 4205187 4205771 R hypothetical protein complement(4205187..4205771) Mycobacterium tuberculosis KZN 1435 8163842 YP_003033824.1 CDS TBMG_03821 NC_012943.1 4205795 4206619 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4205795..4206619 Mycobacterium tuberculosis KZN 1435 8163843 YP_003033825.1 CDS TBMG_03822 NC_012943.1 4206631 4207878 D lipase lipE 4206631..4207878 Mycobacterium tuberculosis KZN 1435 8163844 YP_003033827.1 CDS TBMG_03824 NC_012943.1 4209640 4210626 D oxidoreductase 4209640..4210626 Mycobacterium tuberculosis KZN 1435 8163846 YP_003033828.1 CDS TBMG_03825 NC_012943.1 4210645 4211841 R aminotransferase complement(4210645..4211841) Mycobacterium tuberculosis KZN 1435 8163847 YP_003033829.1 CDS TBMG_03826 NC_012943.1 4211931 4213931 D hypothetical protein 4211931..4213931 Mycobacterium tuberculosis KZN 1435 8163848 YP_003033830.1 CDS TBMG_03827 NC_012943.1 4213935 4214471 D hypothetical protein 4213935..4214471 Mycobacterium tuberculosis KZN 1435 8163849 YP_003033831.1 CDS TBMG_03828 NC_012943.1 4214475 4215296 D O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter rfbE 4214475..4215296 Mycobacterium tuberculosis KZN 1435 8163850 YP_003033832.1 CDS TBMG_03829 NC_012943.1 4215293 4216207 D L-rhamnosyltransferase 4215293..4216207 Mycobacterium tuberculosis KZN 1435 8163851 YP_003033833.1 CDS TBMG_03830 NC_012943.1 4216204 4217046 D hypothetical protein 4216204..4217046 Mycobacterium tuberculosis KZN 1435 8163852 YP_003033834.1 CDS TBMG_03831 NC_012943.1 4217202 4218182 D dTDP-glucose 4,6-dehydratase 4217202..4218182 Mycobacterium tuberculosis KZN 1435 8163853 YP_003033835.1 CDS TBMG_03832 NC_012943.1 4218266 4219339 D hypothetical protein 4218266..4219339 Mycobacterium tuberculosis KZN 1435 8163854 YP_003033836.1 CDS TBMG_03833 NC_012943.1 4219320 4220543 R hypothetical protein complement(4219320..4220543) Mycobacterium tuberculosis KZN 1435 8163855 YP_003033837.1 CDS TBMG_03834 NC_012943.1 4220556 4221482 R hypothetical protein complement(4220556..4221482) Mycobacterium tuberculosis KZN 1435 8163856 YP_003033838.1 CDS TBMG_03835 NC_012943.1 4221726 4222211 D Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 4221726..4222211 Mycobacterium tuberculosis KZN 1435 8163857 YP_003033839.1 CDS TBMG_03836 NC_012943.1 4222257 4222685 D hypothetical protein 4222257..4222685 Mycobacterium tuberculosis KZN 1435 8163858 YP_003033840.1 CDS TBMG_03837 NC_012943.1 4222725 4224110 D oxidoreductase 4222725..4224110 Mycobacterium tuberculosis KZN 1435 8163859 YP_003033841.1 CDS TBMG_03838 NC_012943.1 4224111 4224875 D short chain dehydrogenase 4224111..4224875 Mycobacterium tuberculosis KZN 1435 8163860 YP_003033842.1 CDS TBMG_03839 NC_012943.1 4224878 4226809 D hypothetical protein 4224878..4226809 Mycobacterium tuberculosis KZN 1435 8163861 YP_003033843.1 CDS TBMG_03840 NC_012943.1 4226809 4230093 D membrane indolylacetylinositol arabinosyltransferase embC 4226809..4230093 Mycobacterium tuberculosis KZN 1435 8163862 YP_003033844.1 CDS TBMG_03841 NC_012943.1 4230179 4233463 D membrane indolylacetylinositol arabinosyltransferase embA 4230179..4233463 Mycobacterium tuberculosis KZN 1435 8163863 YP_003033845.1 CDS TBMG_03842 NC_012943.1 4233460 4236756 D membrane indolylacetylinositol arabinosyltransferase embB 4233460..4236756 Mycobacterium tuberculosis KZN 1435 8163864 YP_003033846.1 CDS TBMG_03843 NC_012943.1 4236824 4237951 D hypothetical protein 4236824..4237951 Mycobacterium tuberculosis KZN 1435 8163865 YP_003033847.1 CDS TBMG_03844 NC_012943.1 4238031 4239812 D acyl-CoA dehydrogenase 4238031..4239812 Mycobacterium tuberculosis KZN 1435 8163866 YP_003033848.1 CDS TBMG_03845 NC_012943.1 4239939 4241273 D transposase 4239939..4241273 Mycobacterium tuberculosis KZN 1435 8163867 YP_003033849.1 CDS TBMG_03846 NC_012943.1 4241326 4242894 R propionyl-CoA carboxylase subunit beta complement(4241326..4242894) Mycobacterium tuberculosis KZN 1435 8163868 YP_003033850.1 CDS TBMG_03847 NC_012943.1 4242891 4248092 R polyketide synthase complement(4242891..4248092) Mycobacterium tuberculosis KZN 1435 8163869 YP_003033851.1 CDS TBMG_03848 NC_012943.1 4248099 4250012 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(4248099..4250012) Mycobacterium tuberculosis KZN 1435 8163870 YP_003033852.1 CDS TBMG_03849 NC_012943.1 4250301 4251311 R hypothetical protein complement(4250301..4251311) Mycobacterium tuberculosis KZN 1435 8163871 YP_003033853.1 CDS TBMG_03850 NC_012943.1 4251509 4252441 R secreted fibronectin-binding protein antigen protein fbpD complement(4251509..4252441) Mycobacterium tuberculosis KZN 1435 8163872 YP_003033854.1 CDS TBMG_03851 NC_012943.1 4252588 4253604 R secreted fibronectin-binding protein antigen fbpA complement(4252588..4253604) Mycobacterium tuberculosis KZN 1435 8163873 YP_003033855.1 CDS TBMG_03852 NC_012943.1 4253899 4255842 R hypothetical protein complement(4253899..4255842) Mycobacterium tuberculosis KZN 1435 8163874 YP_003033856.1 CDS TBMG_03853 NC_012943.1 4255871 4256779 R catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase complement(4255871..4256779) Mycobacterium tuberculosis KZN 1435 8163875 YP_003033857.1 CDS TBMG_03854 NC_012943.1 4256786 4257319 R hypothetical protein complement(4256786..4257319) Mycobacterium tuberculosis KZN 1435 8163876 YP_003033858.1 CDS TBMG_03855 NC_012943.1 4257312 4259225 R bifunctional UDP-galactofuranosyl transferase glfT complement(4257312..4259225) Mycobacterium tuberculosis KZN 1435 8163877 YP_003033859.1 CDS TBMG_03856 NC_012943.1 4259222 4260421 R UDP-galactopyranose mutase glf complement(4259222..4260421) Mycobacterium tuberculosis KZN 1435 8163878 YP_003033860.1 CDS TBMG_03857 NC_012943.1 4260685 4261539 D exported repetitive protein pirG 4260685..4261539 Mycobacterium tuberculosis KZN 1435 8163879 YP_003033861.1 CDS TBMG_03858 NC_012943.1 4261744 4263363 D hypothetical protein 4261744..4263363 Mycobacterium tuberculosis KZN 1435 8163880 YP_003033862.1 CDS TBMG_03859 NC_012943.1 4263517 4265031 D PE-PGRS family protein 4263517..4265031 Mycobacterium tuberculosis KZN 1435 8163881 YP_003033863.1 CDS TBMG_03860 NC_012943.1 4265340 4266161 R hypothetical protein complement(4265340..4266161) Mycobacterium tuberculosis KZN 1435 8163882 YP_003033864.1 CDS TBMG_03861 NC_012943.1 4266176 4266961 R acyltransferase complement(4266176..4266961) Mycobacterium tuberculosis KZN 1435 8163883 YP_003033865.1 CDS TBMG_03862 NC_012943.1 4266979 4267734 R acyltransferase complement(4266979..4267734) Mycobacterium tuberculosis KZN 1435 8163884 YP_003033866.1 CDS TBMG_03863 NC_012943.1 4267738 4268517 R acyltransferase complement(4267738..4268517) Mycobacterium tuberculosis KZN 1435 8163885 YP_003033867.1 CDS TBMG_03864 NC_012943.1 4268593 4269348 D phosphotransferase 4268593..4269348 Mycobacterium tuberculosis KZN 1435 8163886 YP_003033868.1 CDS TBMG_03865 NC_012943.1 4269395 4270945 D hypothetical protein 4269395..4270945 Mycobacterium tuberculosis KZN 1435 8163887 YP_003033869.1 CDS TBMG_03866 NC_012943.1 4270942 4271277 D hypothetical protein 4270942..4271277 Mycobacterium tuberculosis KZN 1435 8163888 YP_003033870.1 CDS TBMG_03867 NC_012943.1 4271365 4272771 R polyketide synthase complement(4271365..4272771) Mycobacterium tuberculosis KZN 1435 8163889 YP_003033871.1 CDS TBMG_03868 NC_012943.1 4272919 4273632 D hypothetical protein 4272919..4273632 Mycobacterium tuberculosis KZN 1435 8163890 YP_003033872.1 CDS TBMG_03869 NC_012943.1 4273667 4274881 D hypothetical protein 4273667..4274881 Mycobacterium tuberculosis KZN 1435 8163891 YP_003033873.1 CDS TBMG_03870 NC_012943.1 4275206 4278475 R membrane transporter mmpL8 complement(4275206..4278475) Mycobacterium tuberculosis KZN 1435 8164522 YP_003033874.1 CDS TBMG_03871 NC_012943.1 4278585 4280120 R polyketide synthase complement(4278585..4280120) Mycobacterium tuberculosis KZN 1435 8162824 YP_003033875.1 CDS TBMG_03872 NC_012943.1 4280171 4286551 R polyketide synthase complement(4280171..4286551) Mycobacterium tuberculosis KZN 1435 8162825 YP_003033876.1 CDS TBMG_03873 NC_012943.1 4286758 4288512 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 4286758..4288512 Mycobacterium tuberculosis KZN 1435 8162826 YP_003033877.1 CDS TBMG_03874 NC_012943.1 4288509 4289735 R transposase complement(4288509..4289735) Mycobacterium tuberculosis KZN 1435 8162827 YP_003033878.1 CDS TBMG_03875 NC_012943.1 4289732 4290343 R resolvase complement(4289732..4290343) Mycobacterium tuberculosis KZN 1435 8162828 YP_003033879.1 CDS TBMG_03876 NC_012943.1 4290344 4291969 R dehydrogenase complement(4290344..4291969) Mycobacterium tuberculosis KZN 1435 8162829 YP_003033880.1 CDS TBMG_03877 NC_012943.1 4292002 4292631 R TetR family transcriptional regulator complement(4292002..4292631) Mycobacterium tuberculosis KZN 1435 8162830 YP_003033881.1 CDS TBMG_03878 NC_012943.1 4292703 4293185 D hypothetical protein 4292703..4293185 Mycobacterium tuberculosis KZN 1435 8162831 YP_003033882.1 CDS TBMG_04119 NC_012943.1 4293182 4293757 R hypothetical protein complement(4293182..4293757) Mycobacterium tuberculosis KZN 1435 8162832 YP_003033883.1 CDS TBMG_03879 NC_012943.1 4293813 4294604 D AraC family transcriptional regulator 4293813..4294604 Mycobacterium tuberculosis KZN 1435 8162833 YP_003033884.1 CDS TBMG_03880 NC_012943.1 4294601 4295860 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(4294601..4295860) Mycobacterium tuberculosis KZN 1435 8162834 YP_003033885.1 CDS TBMG_03881 NC_012943.1 4295984 4297342 D hypothetical protein 4295984..4297342 Mycobacterium tuberculosis KZN 1435 8162835 YP_003033886.1 CDS TBMG_03882 NC_012943.1 4297347 4297760 D hypothetical protein 4297347..4297760 Mycobacterium tuberculosis KZN 1435 8162836 YP_003033887.1 CDS TBMG_03883 NC_012943.1 4297955 4298653 R phosphoglycerate mutase complement(4297955..4298653) Mycobacterium tuberculosis KZN 1435 8162837 YP_003033888.1 CDS TBMG_03884 NC_012943.1 4298650 4299615 R catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase complement(4298650..4299615) Mycobacterium tuberculosis KZN 1435 8162838 YP_003033889.1 CDS TBMG_03885 NC_012943.1 4299711 4300487 D hypothetical protein 4299711..4300487 Mycobacterium tuberculosis KZN 1435 8162839 YP_003033890.1 CDS TBMG_03886 NC_012943.1 4300513 4300926 D transcriptional regulator 4300513..4300926 Mycobacterium tuberculosis KZN 1435 8162840 YP_003033891.1 CDS TBMG_03887 NC_012943.1 4301124 4301669 D bacterioferritin bfrB 4301124..4301669 Mycobacterium tuberculosis KZN 1435 8162841 YP_003033892.1 CDS TBMG_03888 NC_012943.1 4301684 4302508 R glycerophosphoryl diester phosphodiesterase glpQ1 complement(4301684..4302508) Mycobacterium tuberculosis KZN 1435 8162842 YP_003033893.1 CDS TBMG_03889 NC_012943.1 4302514 4303542 R hypothetical protein complement(4302514..4303542) Mycobacterium tuberculosis KZN 1435 8162843 YP_003033894.1 CDS TBMG_03890 NC_012943.1 4304631 4304843 R hypothetical protein complement(4304631..4304843) Mycobacterium tuberculosis KZN 1435 8162844 YP_003033895.1 CDS TBMG_03891 NC_012943.1 4305193 4305702 R hypothetical protein complement(4305193..4305702) Mycobacterium tuberculosis KZN 1435 8162845 YP_003033896.1 CDS TBMG_03892 NC_012943.1 4305721 4306212 D transposase 4305721..4306212 Mycobacterium tuberculosis KZN 1435 8162846 YP_003033897.1 CDS TBMG_03893 NC_012943.1 4306227 4306586 D hypothetical protein 4306227..4306586 Mycobacterium tuberculosis KZN 1435 8162847 YP_003033898.1 CDS TBMG_03894 NC_012943.1 4306771 4306986 D hypothetical protein 4306771..4306986 Mycobacterium tuberculosis KZN 1435 8162848 YP_003033899.1 CDS TBMG_03895 NC_012943.1 4307650 4308273 D superoxide dismutase [Fe] sodA 4307650..4308273 Mycobacterium tuberculosis KZN 1435 8162849 YP_003033900.1 CDS TBMG_03896 NC_012943.1 4308484 4309017 D hypothetical protein 4308484..4309017 Mycobacterium tuberculosis KZN 1435 8162850 YP_003033901.1 CDS TBMG_03897 NC_012943.1 4309272 4310180 D hypothetical protein 4309272..4310180 Mycobacterium tuberculosis KZN 1435 8162851 YP_003033902.1 CDS TBMG_03898 NC_012943.1 4310445 4310843 D hypothetical protein 4310445..4310843 Mycobacterium tuberculosis KZN 1435 8162852 YP_003033903.1 CDS TBMG_03899 NC_012943.1 4310961 4311617 D hypothetical protein 4310961..4311617 Mycobacterium tuberculosis KZN 1435 8162853 YP_003033904.1 CDS TBMG_03900 NC_012943.1 4311629 4311913 D hypothetical protein 4311629..4311913 Mycobacterium tuberculosis KZN 1435 8162854 YP_003033905.1 CDS TBMG_03901 NC_012943.1 4311999 4312424 D histone-like protein hns 4311999..4312424 Mycobacterium tuberculosis KZN 1435 8162855 YP_003033906.1 CDS TBMG_03902 NC_012943.1 4312441 4312914 D regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4312441..4312914 Mycobacterium tuberculosis KZN 1435 8162856 YP_003033907.1 CDS TBMG_03903 NC_012943.1 4312950 4314419 R monooxygenase ethA complement(4312950..4314419) Mycobacterium tuberculosis KZN 1435 8162857 YP_003033908.1 CDS TBMG_03904 NC_012943.1 4314495 4315145 D TetR family transcriptional regulator 4314495..4315145 Mycobacterium tuberculosis KZN 1435 8162858 YP_003033909.1 CDS TBMG_03905 NC_012943.1 4315347 4316354 R hypothetical protein complement(4315347..4316354) Mycobacterium tuberculosis KZN 1435 8162859 YP_003033910.1 CDS TBMG_03906 NC_012943.1 4316363 4316560 R hypothetical protein complement(4316363..4316560) Mycobacterium tuberculosis KZN 1435 8162860 YP_003033911.1 CDS gltD NC_012943.1 4316985 4318451 R glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta complement(4316985..4318451) Mycobacterium tuberculosis KZN 1435 8162861 YP_003033912.1 CDS TBMG_03908 NC_012943.1 4318444 4323027 R ferredoxin-dependent glutamate synthase [NADPH] large subunit gltB complement(4318444..4323027) Mycobacterium tuberculosis KZN 1435 8162862 YP_003033913.1 CDS TBMG_03909 NC_012943.1 4323724 4324896 D hypothetical protein 4323724..4324896 Mycobacterium tuberculosis KZN 1435 8162863 YP_003033914.1 CDS TBMG_03910 NC_012943.1 4325118 4325468 R transcriptional regulator whiB-like whiB6 complement(4325118..4325468) Mycobacterium tuberculosis KZN 1435 8162864 YP_003033915.1 CDS TBMG_03911 NC_012943.1 4325795 4326973 D hypothetical protein 4325795..4326973 Mycobacterium tuberculosis KZN 1435 8162865 YP_003033916.1 CDS TBMG_03912 NC_012943.1 4327216 4328424 D hypothetical protein 4327216..4328424 Mycobacterium tuberculosis KZN 1435 8162866 YP_003033917.1 CDS TBMG_03913 NC_012943.1 4328512 4328823 D hypothetical protein 4328512..4328823 Mycobacterium tuberculosis KZN 1435 8162867 YP_003033918.1 CDS TBMG_03914 NC_012943.1 4328826 4329677 D hypothetical protein 4328826..4329677 Mycobacterium tuberculosis KZN 1435 8162868 YP_003033919.1 CDS TBMG_03915 NC_012943.1 4329716 4330267 D hypothetical protein 4329716..4330267 Mycobacterium tuberculosis KZN 1435 8162869 YP_003033920.1 CDS TBMG_03916 NC_012943.1 4330260 4331981 D hypothetical protein 4330260..4331981 Mycobacterium tuberculosis KZN 1435 8162870 YP_003033921.1 CDS TBMG_03917 NC_012943.1 4331985 4333427 D hypothetical protein 4331985..4333427 Mycobacterium tuberculosis KZN 1435 8162871 YP_003033922.1 CDS TBMG_03918 NC_012943.1 4333427 4335670 D hypothetical protein 4333427..4335670 Mycobacterium tuberculosis KZN 1435 8162872 YP_003033923.1 CDS TBMG_03919 NC_012943.1 4335773 4337548 D hypothetical protein 4335773..4337548 Mycobacterium tuberculosis KZN 1435 8162873 YP_003033924.1 CDS TBMG_03920 NC_012943.1 4337691 4337987 D hypothetical protein 4337691..4337987 Mycobacterium tuberculosis KZN 1435 8162874 YP_003033925.1 CDS TBMG_03921 NC_012943.1 4338012 4339127 D PPE family protein 4338012..4339127 Mycobacterium tuberculosis KZN 1435 8162875 YP_003033926.1 CDS TBMG_03922 NC_012943.1 4339220 4339522 D 10 kDa culture filtrate antigen esxB 4339220..4339522 Mycobacterium tuberculosis KZN 1435 8162876 YP_003033927.1 CDS TBMG_03923 NC_012943.1 4339555 4339842 D hypothetical protein 4339555..4339842 Mycobacterium tuberculosis KZN 1435 8162877 YP_003033928.1 CDS TBMG_03924 NC_012943.1 4339956 4341956 D hypothetical protein 4339956..4341956 Mycobacterium tuberculosis KZN 1435 8162878 YP_003033929.1 CDS TBMG_03925 NC_012943.1 4341953 4343488 D hypothetical protein 4341953..4343488 Mycobacterium tuberculosis KZN 1435 8162879 YP_003033930.1 CDS TBMG_03926 NC_012943.1 4343639 4344481 D hypothetical protein 4343639..4344481 Mycobacterium tuberculosis KZN 1435 8162880 YP_003033931.1 CDS TBMG_03927 NC_012943.1 4344539 4346728 R hypothetical protein complement(4344539..4346728) Mycobacterium tuberculosis KZN 1435 8162881 YP_003033932.1 CDS TBMG_03928 NC_012943.1 4347145 4347492 R hypothetical protein complement(4347145..4347492) Mycobacterium tuberculosis KZN 1435 8162882 YP_003033933.1 CDS TBMG_03929 NC_012943.1 4347489 4348871 R hypothetical protein complement(4347489..4348871) Mycobacterium tuberculosis KZN 1435 8162883 YP_003033934.1 CDS TBMG_03930 NC_012943.1 4348978 4350366 R hypothetical protein complement(4348978..4350366) Mycobacterium tuberculosis KZN 1435 8162884 YP_003033935.1 CDS TBMG_03931 NC_012943.1 4350363 4351733 R membrane-anchored mycosin mycP1 complement(4350363..4351733) Mycobacterium tuberculosis KZN 1435 8162885 YP_003033936.1 CDS TBMG_03932 NC_012943.1 4351925 4353784 R cbxX/cfqX family protein complement(4351925..4353784) Mycobacterium tuberculosis KZN 1435 8162886 YP_003033937.1 CDS TBMG_03933 NC_012943.1 4353854 4355467 R hypothetical protein complement(4353854..4355467) Mycobacterium tuberculosis KZN 1435 8162887 YP_003033938.1 CDS TBMG_03934 NC_012943.1 4355464 4357182 R hypothetical protein complement(4355464..4357182) Mycobacterium tuberculosis KZN 1435 8162888 YP_003033939.1 CDS TBMG_03935 NC_012943.1 4357101 4358630 R hypothetical protein complement(4357101..4358630) Mycobacterium tuberculosis KZN 1435 8162889 YP_003033940.1 CDS TBMG_03936 NC_012943.1 4358627 4359652 R hypothetical protein complement(4358627..4359652) Mycobacterium tuberculosis KZN 1435 8162890 YP_003033941.1 CDS TBMG_03937 NC_012943.1 4359746 4360576 R hypothetical protein complement(4359746..4360576) Mycobacterium tuberculosis KZN 1435 8162891 YP_003033942.1 CDS TBMG_03938 NC_012943.1 4360672 4360959 R esat-6 like protein esxC complement(4360672..4360959) Mycobacterium tuberculosis KZN 1435 8162892 YP_003033943.1 CDS TBMG_03939 NC_012943.1 4360995 4361318 R esat-6 like protein esxD complement(4360995..4361318) Mycobacterium tuberculosis KZN 1435 8162893 YP_003033944.1 CDS TBMG_03940 NC_012943.1 4361430 4362629 R PPE family protein complement(4361430..4362629) Mycobacterium tuberculosis KZN 1435 8162894 YP_003033945.1 CDS TBMG_03941 NC_012943.1 4362708 4362941 R PE family protein complement(4362708..4362941) Mycobacterium tuberculosis KZN 1435 8162895 YP_003033946.1 CDS TBMG_03942 NC_012943.1 4363208 4367398 R hypothetical protein complement(4363208..4367398) Mycobacterium tuberculosis KZN 1435 8162896 YP_003033947.1 CDS TBMG_03943 NC_012943.1 4367399 4368886 R hypothetical protein complement(4367399..4368886) Mycobacterium tuberculosis KZN 1435 8162897 YP_003033948.1 CDS TBMG_03944 NC_012943.1 4368889 4369797 R hypothetical protein complement(4368889..4369797) Mycobacterium tuberculosis KZN 1435 8162898 YP_003033949.1 CDS TBMG_03945 NC_012943.1 4369947 4370591 R hypothetical protein complement(4369947..4370591) Mycobacterium tuberculosis KZN 1435 8162899 YP_003033950.1 CDS TBMG_03946 NC_012943.1 4370604 4370942 R hypothetical protein complement(4370604..4370942) Mycobacterium tuberculosis KZN 1435 8162900 YP_003033951.1 CDS TBMG_03947 NC_012943.1 4371098 4372330 R hypothetical protein complement(4371098..4372330) Mycobacterium tuberculosis KZN 1435 8162901 YP_003033952.1 CDS TBMG_03948 NC_012943.1 4372324 4373259 R hypothetical protein complement(4372324..4373259) Mycobacterium tuberculosis KZN 1435 8162902 YP_003033953.1 CDS TBMG_03949 NC_012943.1 4373316 4373765 R hypothetical protein complement(4373316..4373765) Mycobacterium tuberculosis KZN 1435 8162903 YP_003033954.1 CDS TBMG_03950 NC_012943.1 4374316 4374846 R hypothetical protein complement(4374316..4374846) Mycobacterium tuberculosis KZN 1435 8162904 YP_003033955.1 CDS TBMG_03951 NC_012943.1 4374843 4377383 R hypothetical protein complement(4374843..4377383) Mycobacterium tuberculosis KZN 1435 8161212 YP_003033956.1 CDS TBMG_03952 NC_012943.1 4377388 4377660 R esat-6 like protein esxE complement(4377388..4377660) Mycobacterium tuberculosis KZN 1435 8161213 YP_003033957.1 CDS TBMG_03953 NC_012943.1 4377671 4377982 R esat-6 like protein esxF complement(4377671..4377982) Mycobacterium tuberculosis KZN 1435 8161214 YP_003033958.1 CDS TBMG_03954 NC_012943.1 4378048 4378557 R hypothetical protein complement(4378048..4378557) Mycobacterium tuberculosis KZN 1435 8161215 YP_003033959.1 CDS TBMG_03955 NC_012943.1 4378582 4380024 R poly(A) polymerase complement(4378582..4380024) Mycobacterium tuberculosis KZN 1435 8161216 YP_003033960.1 CDS TBMG_03956 NC_012943.1 4380400 4381146 D hypothetical protein 4380400..4381146 Mycobacterium tuberculosis KZN 1435 8161217 YP_003033961.1 CDS TBMG_03957 NC_012943.1 4381143 4383551 D hypothetical protein 4381143..4383551 Mycobacterium tuberculosis KZN 1435 8161218 YP_003033962.1 CDS TBMG_03958 NC_012943.1 4383548 4387102 D hypothetical protein 4383548..4387102 Mycobacterium tuberculosis KZN 1435 8161219 YP_003033963.1 CDS TBMG_03959 NC_012943.1 4387137 4387727 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase; RNA polymerase sigma factor SigM 4387137..4387727 Mycobacterium tuberculosis KZN 1435 8161220 YP_003033964.1 CDS TBMG_03960 NC_012943.1 4387820 4388584 D hypothetical protein 4387820..4388584 Mycobacterium tuberculosis KZN 1435 8161221 YP_003033965.1 CDS TBMG_03961 NC_012943.1 4388678 4389685 D thioredoxin reductase trxB2 4388678..4389685 Mycobacterium tuberculosis KZN 1435 8161222 YP_003033966.1 CDS TBMG_03962 NC_012943.1 4389682 4390032 D thioredoxin trxC 4389682..4390032 Mycobacterium tuberculosis KZN 1435 8161223 YP_003033967.1 CDS TBMG_03963 NC_012943.1 4390142 4391362 D hydrolase 4390142..4391362 Mycobacterium tuberculosis KZN 1435 8161224 YP_003033968.1 CDS TBMG_03964 NC_012943.1 4391383 4392117 R hypothetical protein complement(4391383..4392117) Mycobacterium tuberculosis KZN 1435 8161225 YP_003033969.1 CDS TBMG_03965 NC_012943.1 4392407 4393441 R chromosome partitioning protein parB complement(4392407..4393441) Mycobacterium tuberculosis KZN 1435 8161226 YP_003033970.1 CDS TBMG_03966 NC_012943.1 4393438 4394481 R chromosome partitioning protein parA complement(4393438..4394481) Mycobacterium tuberculosis KZN 1435 8161227 YP_003033971.1 CDS TBMG_03967 NC_012943.1 4394478 4394891 R glucose-inhibited division protein B complement(4394478..4394891) Mycobacterium tuberculosis KZN 1435 8161228 YP_003033972.1 CDS TBMG_03968 NC_012943.1 4395154 4395717 R hypothetical protein complement(4395154..4395717) Mycobacterium tuberculosis KZN 1435 8161229 YP_003033973.1 CDS TBMG_03969 NC_012943.1 4395789 4396889 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC complement(4395789..4396889) Mycobacterium tuberculosis KZN 1435 8161230 YP_003033974.1 CDS TBMG_03970 NC_012943.1 4396873 4397235 R hypothetical protein complement(4396873..4397235) Mycobacterium tuberculosis KZN 1435 8161231 YP_003033975.1 CDS rnpA NC_012943.1 4397232 4397609 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(4397232..4397609) Mycobacterium tuberculosis KZN 1435 8161232 YP_003033976.1 CDS rpmH NC_012943.1 4397606 4397749 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(4397606..4397749) Mycobacterium tuberculosis KZN 1435 8161233 TBMG_05001 tRNA TBMG_05001 NC_012943.1 10989 11065 D tRNA-Ile 10989..11065 Mycobacterium tuberculosis KZN 1435 8163713 TBMG_05002 tRNA TBMG_05002 NC_012943.1 11214 11289 D tRNA-Ala 11214..11289 Mycobacterium tuberculosis KZN 1435 8163714 TBMG_05003 tRNA TBMG_05003 NC_012943.1 25746 25831 D tRNA-Leu 25746..25831 Mycobacterium tuberculosis KZN 1435 8163728 TBMG_05004 tRNA TBMG_05004 NC_012943.1 389087 389160 R tRNA-Gly complement(389087..389160) Mycobacterium tuberculosis KZN 1435 8162495 TBMG_05005 tRNA TBMG_05005 NC_012943.1 658370 658453 D tRNA-Tyr 658370..658453 Mycobacterium tuberculosis KZN 1435 8161977 TBMG_05006 tRNA TBMG_05006 NC_012943.1 731746 731818 D tRNA-Thr 731746..731818 Mycobacterium tuberculosis KZN 1435 8163291 TBMG_05007 tRNA TBMG_05007 NC_012943.1 731855 731931 D tRNA-Met 731855..731931 Mycobacterium tuberculosis KZN 1435 8163292 TBMG_05008 tRNA TBMG_05008 NC_012943.1 733776 733848 D tRNA-Trp 733776..733848 Mycobacterium tuberculosis KZN 1435 8163297 TBMG_05009 tRNA TBMG_05009 NC_012943.1 851837 851911 R tRNA-Thr complement(851837..851911) Mycobacterium tuberculosis KZN 1435 8162950 TBMG_05010 tRNA TBMG_05010 NC_012943.1 923642 923717 R tRNA-Lys complement(923642..923717) Mycobacterium tuberculosis KZN 1435 8161087 TBMG_05011 tRNA TBMG_05011 NC_012943.1 923841 923917 D tRNA-Glu 923841..923917 Mycobacterium tuberculosis KZN 1435 8161088 TBMG_05012 tRNA TBMG_05012 NC_012943.1 923952 924028 D tRNA-Asp 923952..924028 Mycobacterium tuberculosis KZN 1435 8161089 TBMG_05013 tRNA TBMG_05013 NC_012943.1 924055 924131 D tRNA-Phe 924055..924131 Mycobacterium tuberculosis KZN 1435 8161090 TBMG_05014 tRNA TBMG_05014 NC_012943.1 981864 981936 D tRNA-Ala 981864..981936 Mycobacterium tuberculosis KZN 1435 8163935 TBMG_05015 tRNA TBMG_05015 NC_012943.1 1065049 1065120 D tRNA-Gln 1065049..1065120 Mycobacterium tuberculosis KZN 1435 8162269 TBMG_05016 tRNA TBMG_05016 NC_012943.1 1065160 1065235 D tRNA-Glu 1065160..1065235 Mycobacterium tuberculosis KZN 1435 8162270 TBMG_05017 tRNA TBMG_05017 NC_012943.1 1443799 1443873 R tRNA-Val complement(1443799..1443873) Mycobacterium tuberculosis KZN 1435 8162378 TBMG_05018 tRNA TBMG_05018 NC_012943.1 1443887 1443960 R tRNA-Cys complement(1443887..1443960) Mycobacterium tuberculosis KZN 1435 8162379 TBMG_05019 tRNA TBMG_05019 NC_012943.1 1443987 1444062 R tRNA-Gly complement(1443987..1444062) Mycobacterium tuberculosis KZN 1435 8162380 TBMG_05020 tRNA TBMG_05020 NC_012943.1 1444247 1444321 D tRNA-Val 1444247..1444321 Mycobacterium tuberculosis KZN 1435 8162381 TBMG_05021 tRNA TBMG_05021 NC_012943.1 1578248 1578320 R tRNA-Lys complement(1578248..1578320) Mycobacterium tuberculosis KZN 1435 8163225 TBMG_05022 tRNA TBMG_05022 NC_012943.1 1585885 1585960 R tRNA-His complement(1585885..1585960) Mycobacterium tuberculosis KZN 1435 8163232 TBMG_05023 tRNA TBMG_05023 NC_012943.1 1620791 1620864 R tRNA-Arg complement(1620791..1620864) Mycobacterium tuberculosis KZN 1435 8163261 TBMG_05024 tRNA TBMG_05024 NC_012943.1 1648068 1648138 R tRNA-Gly complement(1648068..1648138) Mycobacterium tuberculosis KZN 1435 8163284 TBMG_05025 tRNA TBMG_05025 NC_012943.1 1648275 1648351 D tRNA-Pro 1648275..1648351 Mycobacterium tuberculosis KZN 1435 8163285 TBMG_05026 tRNA TBMG_05026 NC_012943.1 1797112 1797184 D tRNA-Asn 1797112..1797184 Mycobacterium tuberculosis KZN 1435 8162705 TBMG_05027 tRNA TBMG_05027 NC_012943.1 1834755 1834828 D tRNA-Met 1834755..1834828 Mycobacterium tuberculosis KZN 1435 8162741 TBMG_05028 tRNA TBMG_05028 NC_012943.1 1905922 1905996 D tRNA-Val 1905922..1905996 Mycobacterium tuberculosis KZN 1435 8161391 TBMG_05029 tRNA TBMG_05029 NC_012943.1 2013100 2013188 R tRNA-Leu complement(2013100..2013188) Mycobacterium tuberculosis KZN 1435 8161658 TBMG_05030 tRNA TBMG_05030 NC_012943.1 2476017 2476090 R tRNA-Pro complement(2476017..2476090) Mycobacterium tuberculosis KZN 1435 8164049 TBMG_05031 tRNA TBMG_05031 NC_012943.1 2594624 2594700 D tRNA-Leu 2594624..2594700 Mycobacterium tuberculosis KZN 1435 8160642 TBMG_05032 tRNA TBMG_05032 NC_012943.1 2899536 2899619 R tRNA-Leu complement(2899536..2899619) Mycobacterium tuberculosis KZN 1435 8162194 TBMG_05033 tRNA TBMG_05033 NC_012943.1 2966026 2966101 D tRNA-Arg 2966026..2966101 Mycobacterium tuberculosis KZN 1435 8161133 TBMG_05034 tRNA TBMG_05034 NC_012943.1 3234497 3234570 R tRNA-Leu complement(3234497..3234570) Mycobacterium tuberculosis KZN 1435 8161935 TBMG_05035 tRNA TBMG_05035 NC_012943.1 3273820 3273891 D tRNA-Gln 3273820..3273891 Mycobacterium tuberculosis KZN 1435 8164085 TBMG_05036 tRNA TBMG_05036 NC_012943.1 3298381 3298456 R tRNA-Ala complement(3298381..3298456) Mycobacterium tuberculosis KZN 1435 8164110 TBMG_05037 tRNA TBMG_05037 NC_012943.1 3386584 3386656 D tRNA-Arg 3386584..3386656 Mycobacterium tuberculosis KZN 1435 8161429 TBMG_05038 tRNA TBMG_05038 NC_012943.1 3557474 3557550 R tRNA-Met complement(3557474..3557550) Mycobacterium tuberculosis KZN 1435 8162617 TBMG_05039 tRNA TBMG_05039 NC_012943.1 4068079 4068154 R tRNA-Thr complement(4068079..4068154) Mycobacterium tuberculosis KZN 1435 8163916 TBMG_05040 tRNA TBMG_05040 NC_012943.1 4113427 4113503 D tRNA-Pro 4113427..4113503 Mycobacterium tuberculosis KZN 1435 8164538 TBMG_05041 tRNA TBMG_05041 NC_012943.1 4155290 4155378 D tRNA-Ser 4155290..4155378 Mycobacterium tuberculosis KZN 1435 8164579 TBMG_05042 tRNA TBMG_05042 NC_012943.1 4186074 4186163 R tRNA-Ser complement(4186074..4186163) Mycobacterium tuberculosis KZN 1435 8163816 TBMG_05043 tRNA TBMG_05043 NC_012943.1 4203811 4203883 R tRNA-Arg complement(4203811..4203883) Mycobacterium tuberculosis KZN 1435 8163839 TBMG_05044 tRNA TBMG_05044 NC_012943.1 4203914 4204002 R tRNA-Ser complement(4203914..4204002) Mycobacterium tuberculosis KZN 1435 8163840 TBMG_05045 tRNA TBMG_05045 NC_012943.1 4209527 4209613 R tRNA-Ser complement(4209527..4209613) Mycobacterium tuberculosis KZN 1435 8163845 TBMG_05101 rRNA TBMG_05101 NC_012943.1 2935334 2935445 R 5S ribosomal RNA complement(2935334..2935445) Mycobacterium tuberculosis KZN 1435 8162229 TBMG_05102 rRNA TBMG_05102 NC_012943.1 2935556 2938686 R 23S ribosomal RNA complement(join(2935556..2937057,2937099..2938686)) Mycobacterium tuberculosis KZN 1435 8161234 TBMG_05103 rRNA TBMG_05103 NC_012943.1 2938973 2940492 R 16S ribosomal RNA complement(2938973..2940492) Mycobacterium tuberculosis KZN 1435 8161236