-- dump date   	20140619_155818
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
956483000001	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
956483000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483000003	Walker A motif; other site
956483000004	ATP binding site [chemical binding]; other site
956483000005	Walker B motif; other site
956483000006	arginine finger; other site
956483000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
956483000008	DnaA box-binding interface [nucleotide binding]; other site
956483000009	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cl17512
956483000010	putative DNA binding surface [nucleotide binding]; other site
956483000011	DNA polymerase III beta subunit; Region: POL3Bc; smart00480
956483000012	dimer interface [polypeptide binding]; other site
956483000013	beta-clamp/clamp loader binding surface; other site
956483000014	beta-clamp/translesion DNA polymerase binding surface; other site
956483000015	S4 domain; Region: S4_2; cl17325
956483000016	HTH-like domain; Region: HTH_21; pfam13276
956483000017	Integrase core domain; Region: rve; pfam00665
956483000018	Integrase core domain; Region: rve_3; cl15866
956483000019	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
956483000020	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
956483000021	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
956483000022	nucleophilic elbow; other site
956483000023	catalytic triad; other site
956483000024	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
956483000025	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
956483000026	catalytic site [active]
956483000027	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
956483000028	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
956483000029	putative active site [active]
956483000030	putative FMN binding site [chemical binding]; other site
956483000031	putative substrate binding site [chemical binding]; other site
956483000032	putative catalytic residue [active]
956483000033	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
956483000034	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
956483000035	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
956483000036	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
956483000037	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
956483000038	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
956483000039	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
956483000040	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
956483000041	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
956483000042	lipoyl-biotinyl attachment site [posttranslational modification]; other site
956483000043	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
956483000044	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
956483000045	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
956483000046	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000047	Walker A/P-loop; other site
956483000048	ATP binding site [chemical binding]; other site
956483000049	Q-loop/lid; other site
956483000050	ABC transporter signature motif; other site
956483000051	Walker B; other site
956483000052	D-loop; other site
956483000053	H-loop/switch region; other site
956483000054	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
956483000055	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
956483000056	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
956483000057	TM-ABC transporter signature motif; other site
956483000058	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
956483000059	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
956483000060	TM-ABC transporter signature motif; other site
956483000061	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
956483000062	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
956483000063	active site
956483000064	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
956483000065	active site
956483000066	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
956483000067	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
956483000068	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
956483000069	substrate binding site [chemical binding]; other site
956483000070	ATP binding site [chemical binding]; other site
956483000071	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
956483000072	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
956483000073	active site
956483000074	motif I; other site
956483000075	motif II; other site
956483000076	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
956483000077	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
956483000078	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
956483000079	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
956483000080	Walker A/P-loop; other site
956483000081	ATP binding site [chemical binding]; other site
956483000082	Q-loop/lid; other site
956483000083	ABC transporter signature motif; other site
956483000084	Walker B; other site
956483000085	D-loop; other site
956483000086	H-loop/switch region; other site
956483000087	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000088	AAA domain; Region: AAA_21; pfam13304
956483000089	Walker A/P-loop; other site
956483000090	ATP binding site [chemical binding]; other site
956483000091	Q-loop/lid; other site
956483000092	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
956483000093	ABC transporter signature motif; other site
956483000094	Walker B; other site
956483000095	D-loop; other site
956483000096	H-loop/switch region; other site
956483000097	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
956483000098	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
956483000099	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
956483000100	Walker A/P-loop; other site
956483000101	ATP binding site [chemical binding]; other site
956483000102	Q-loop/lid; other site
956483000103	ABC transporter signature motif; other site
956483000104	Walker B; other site
956483000105	D-loop; other site
956483000106	H-loop/switch region; other site
956483000107	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
956483000108	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
956483000109	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
956483000110	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000111	dimer interface [polypeptide binding]; other site
956483000112	conserved gate region; other site
956483000113	putative PBP binding loops; other site
956483000114	ABC-ATPase subunit interface; other site
956483000115	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
956483000116	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
956483000117	chromosome segregation protein; Provisional; Region: PRK03918
956483000118	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
956483000119	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
956483000120	Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: CysS; COG0215
956483000121	active site
956483000122	HIGH motif; other site
956483000123	nucleotide binding site [chemical binding]; other site
956483000124	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
956483000125	active site
956483000126	KMSKS motif; other site
956483000127	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
956483000128	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
956483000129	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
956483000130	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
956483000131	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
956483000132	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
956483000133	putative homodimer interface [polypeptide binding]; other site
956483000134	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
956483000135	heterodimer interface [polypeptide binding]; other site
956483000136	homodimer interface [polypeptide binding]; other site
956483000137	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
956483000138	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
956483000139	putative nucleotide binding site [chemical binding]; other site
956483000140	uridine monophosphate binding site [chemical binding]; other site
956483000141	homohexameric interface [polypeptide binding]; other site
956483000142	ribosome recycling factor; Reviewed; Region: frr; PRK00083
956483000143	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
956483000144	hinge region; other site
956483000145	Competence protein; Region: Competence; cl00471
956483000146	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
956483000147	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
956483000148	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
956483000149	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
956483000150	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
956483000151	S-adenosylmethionine binding site [chemical binding]; other site
956483000152	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
956483000153	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
956483000154	active site
956483000155	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
956483000156	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
956483000157	trmE is a tRNA modification GTPase; Region: trmE; cd04164
956483000158	G1 box; other site
956483000159	GTP/Mg2+ binding site [chemical binding]; other site
956483000160	Switch I region; other site
956483000161	G2 box; other site
956483000162	Switch II region; other site
956483000163	G3 box; other site
956483000164	G4 box; other site
956483000165	G5 box; other site
956483000166	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
956483000167	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
956483000168	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
956483000169	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
956483000170	seryl-tRNA synthetase; Provisional; Region: PRK05431
956483000171	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
956483000172	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
956483000173	dimer interface [polypeptide binding]; other site
956483000174	active site
956483000175	motif 1; other site
956483000176	motif 2; other site
956483000177	motif 3; other site
956483000178	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
956483000179	active site
956483000180	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
956483000181	Ribonuclease P; Region: Ribonuclease_P; pfam00825
956483000182	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
956483000183	putative inner membrane protein translocase component YidC; Provisional; Region: PRK02201
956483000184	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
956483000185	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
956483000186	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
956483000187	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
956483000188	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
956483000189	Uncharacterized conserved protein [Function unknown]; Region: COG4095
956483000190	Uncharacterized conserved protein [Function unknown]; Region: COG4095
956483000191	asparagine synthetase AsnA; Provisional; Region: PRK05425
956483000192	motif 1; other site
956483000193	dimer interface [polypeptide binding]; other site
956483000194	active site
956483000195	motif 2; other site
956483000196	motif 3; other site
956483000197	DNA polymerase III PolC; Validated; Region: polC; PRK00448
956483000198	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
956483000199	generic binding surface II; other site
956483000200	generic binding surface I; other site
956483000201	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
956483000202	active site
956483000203	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
956483000204	active site
956483000205	catalytic site [active]
956483000206	substrate binding site [chemical binding]; other site
956483000207	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
956483000208	recombination factor protein RarA; Reviewed; Region: PRK13342
956483000209	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483000210	Walker A motif; other site
956483000211	ATP binding site [chemical binding]; other site
956483000212	Walker B motif; other site
956483000213	arginine finger; other site
956483000214	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
956483000215	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
956483000216	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
956483000217	dimer interface [polypeptide binding]; other site
956483000218	motif 1; other site
956483000219	active site
956483000220	motif 2; other site
956483000221	motif 3; other site
956483000222	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
956483000223	ligand binding site [chemical binding]; other site
956483000224	active site
956483000225	UGI interface [polypeptide binding]; other site
956483000226	catalytic site [active]
956483000227	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
956483000228	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
956483000229	putative tRNA-binding site [nucleotide binding]; other site
956483000230	B3/4 domain; Region: B3_4; pfam03483
956483000231	tRNA synthetase B5 domain; Region: B5; pfam03484
956483000232	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
956483000233	motif 1; other site
956483000234	dimer interface [polypeptide binding]; other site
956483000235	motif 2; other site
956483000236	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
956483000237	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
956483000238	dimer interface [polypeptide binding]; other site
956483000239	active site
956483000240	glycine-pyridoxal phosphate binding site [chemical binding]; other site
956483000241	folate binding site [chemical binding]; other site
956483000242	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
956483000243	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
956483000244	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
956483000245	Aminotransferase class-V; Region: Aminotran_5; pfam00266
956483000246	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
956483000247	catalytic residue [active]
956483000248	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
956483000249	trimerization site [polypeptide binding]; other site
956483000250	active site
956483000251	DNA polymerase IV; Validated; Region: PRK01810
956483000252	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
956483000253	active site
956483000254	DNA binding site [nucleotide binding]
956483000255	putative nicotinate-nucleotide adenylyltransferase; Validated; Region: nadD; PRK07152
956483000256	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
956483000257	active site
956483000258	(T/H)XGH motif; other site
956483000259	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
956483000260	Zn2+ binding site [ion binding]; other site
956483000261	Mg2+ binding site [ion binding]; other site
956483000262	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
956483000263	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
956483000264	RNA binding surface [nucleotide binding]; other site
956483000265	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
956483000266	active site
956483000267	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
956483000268	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
956483000269	intersubunit interface [polypeptide binding]; other site
956483000270	active site
956483000271	zinc binding site [ion binding]; other site
956483000272	Na+ binding site [ion binding]; other site
956483000273	Staphylococcal nuclease homologues; Region: SNc; smart00318
956483000274	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140
956483000275	Catalytic site; other site
956483000276	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
956483000277	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
956483000278	23S rRNA interface [nucleotide binding]; other site
956483000279	L7/L12 interface [polypeptide binding]; other site
956483000280	putative thiostrepton binding site; other site
956483000281	L25 interface [polypeptide binding]; other site
956483000282	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
956483000283	mRNA/rRNA interface [nucleotide binding]; other site
956483000284	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
956483000285	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
956483000286	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
956483000287	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
956483000288	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
956483000289	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
956483000290	GTP/Mg2+ binding site [chemical binding]; other site
956483000291	G4 box; other site
956483000292	G5 box; other site
956483000293	G1 box; other site
956483000294	Switch I region; other site
956483000295	G2 box; other site
956483000296	G3 box; other site
956483000297	Switch II region; other site
956483000298	HPr kinase/phosphorylase; Provisional; Region: PRK05428
956483000299	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
956483000300	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
956483000301	Hpr binding site; other site
956483000302	active site
956483000303	homohexamer subunit interaction site [polypeptide binding]; other site
956483000304	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
956483000305	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
956483000306	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
956483000307	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
956483000308	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
956483000309	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
956483000310	tetramer interface [polypeptide binding]; other site
956483000311	TPP-binding site [chemical binding]; other site
956483000312	heterodimer interface [polypeptide binding]; other site
956483000313	phosphorylation loop region [posttranslational modification]
956483000314	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
956483000315	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
956483000316	alpha subunit interface [polypeptide binding]; other site
956483000317	TPP binding site [chemical binding]; other site
956483000318	heterodimer interface [polypeptide binding]; other site
956483000319	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
956483000320	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
956483000321	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
956483000322	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
956483000323	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
956483000324	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483000325	Integrase core domain; Region: rve; pfam00665
956483000326	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
956483000327	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
956483000328	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
956483000329	conserved cys residue [active]
956483000330	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
956483000331	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000332	dimer interface [polypeptide binding]; other site
956483000333	conserved gate region; other site
956483000334	putative PBP binding loops; other site
956483000335	ABC-ATPase subunit interface; other site
956483000336	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
956483000337	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000338	dimer interface [polypeptide binding]; other site
956483000339	conserved gate region; other site
956483000340	putative PBP binding loops; other site
956483000341	ABC-ATPase subunit interface; other site
956483000342	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
956483000343	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
956483000344	Walker A/P-loop; other site
956483000345	ATP binding site [chemical binding]; other site
956483000346	Q-loop/lid; other site
956483000347	ABC transporter signature motif; other site
956483000348	Walker B; other site
956483000349	D-loop; other site
956483000350	H-loop/switch region; other site
956483000351	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
956483000352	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
956483000353	Walker A/P-loop; other site
956483000354	ATP binding site [chemical binding]; other site
956483000355	Q-loop/lid; other site
956483000356	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14246
956483000357	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
956483000358	ABC transporter signature motif; other site
956483000359	Walker B; other site
956483000360	D-loop; other site
956483000361	H-loop/switch region; other site
956483000362	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
956483000363	Uncharacterized conserved protein [Function unknown]; Region: COG1284
956483000364	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
956483000365	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
956483000366	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
956483000367	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
956483000368	putative active site [active]
956483000369	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000370	Walker A/P-loop; other site
956483000371	ATP binding site [chemical binding]; other site
956483000372	Q-loop/lid; other site
956483000373	ABC transporter signature motif; other site
956483000374	Walker B; other site
956483000375	D-loop; other site
956483000376	H-loop/switch region; other site
956483000377	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
956483000378	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
956483000379	active site
956483000380	catalytic motif [active]
956483000381	Zn binding site [ion binding]; other site
956483000382	GTPase Era; Reviewed; Region: era; PRK00089
956483000383	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
956483000384	G1 box; other site
956483000385	GTP/Mg2+ binding site [chemical binding]; other site
956483000386	Switch I region; other site
956483000387	G2 box; other site
956483000388	Switch II region; other site
956483000389	G3 box; other site
956483000390	G4 box; other site
956483000391	G5 box; other site
956483000392	KH domain; Region: KH_2; pfam07650
956483000393	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
956483000394	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
956483000395	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
956483000396	active site
956483000397	prolyl-tRNA synthetase; Provisional; Region: PRK08661
956483000398	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
956483000399	dimer interface [polypeptide binding]; other site
956483000400	motif 1; other site
956483000401	active site
956483000402	motif 2; other site
956483000403	motif 3; other site
956483000404	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
956483000405	anticodon binding site; other site
956483000406	zinc-binding site [ion binding]; other site
956483000407	LemA family; Region: LemA; cl00742
956483000408	putative phosphoketolase; Provisional; Region: PRK05261
956483000409	XFP N-terminal domain; Region: XFP_N; pfam09364
956483000410	XFP C-terminal domain; Region: XFP_C; pfam09363
956483000411	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483000412	Helix-turn-helix domain; Region: HTH_38; pfam13936
956483000413	Integrase core domain; Region: rve; pfam00665
956483000414	oligoendopeptidase F; Region: pepF; TIGR00181
956483000415	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
956483000416	active site
956483000417	Zn binding site [ion binding]; other site
956483000418	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000419	AAA domain; Region: AAA_21; pfam13304
956483000420	Walker A/P-loop; other site
956483000421	ATP binding site [chemical binding]; other site
956483000422	Q-loop/lid; other site
956483000423	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
956483000424	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000425	ABC transporter signature motif; other site
956483000426	Walker B; other site
956483000427	D-loop; other site
956483000428	H-loop/switch region; other site
956483000429	TOBE domain; Region: TOBE_2; pfam08402
956483000430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000431	dimer interface [polypeptide binding]; other site
956483000432	conserved gate region; other site
956483000433	putative PBP binding loops; other site
956483000434	ABC-ATPase subunit interface; other site
956483000435	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
956483000436	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000437	dimer interface [polypeptide binding]; other site
956483000438	conserved gate region; other site
956483000439	putative PBP binding loops; other site
956483000440	ABC-ATPase subunit interface; other site
956483000441	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
956483000442	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483000443	Helix-turn-helix domain; Region: HTH_38; pfam13936
956483000444	Integrase core domain; Region: rve; pfam00665
956483000445	variable surface protein Vir28; Provisional; Region: PTZ00249
956483000446	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
956483000447	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
956483000448	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
956483000449	Ligand Binding Site [chemical binding]; other site
956483000450	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483000451	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483000452	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
956483000453	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483000454	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483000455	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
956483000456	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
956483000457	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
956483000458	active site
956483000459	HIGH motif; other site
956483000460	nucleotide binding site [chemical binding]; other site
956483000461	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
956483000462	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
956483000463	active site
956483000464	KMSKS motif; other site
956483000465	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
956483000466	tRNA binding surface [nucleotide binding]; other site
956483000467	anticodon binding site; other site
956483000468	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
956483000469	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
956483000470	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
956483000471	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
956483000472	homodimer interface [polypeptide binding]; other site
956483000473	NADP binding site [chemical binding]; other site
956483000474	substrate binding site [chemical binding]; other site
956483000475	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
956483000476	acetate kinase; Provisional; Region: PRK07157
956483000477	propionate/acetate kinase; Provisional; Region: PRK12379
956483000478	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK13964
956483000479	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
956483000480	active site
956483000481	nucleotide binding site [chemical binding]; other site
956483000482	HIGH motif; other site
956483000483	KMSKS motif; other site
956483000484	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
956483000485	G1 box; other site
956483000486	GTP/Mg2+ binding site [chemical binding]; other site
956483000487	Elongation factor Tu GTP binding domain; Region: GTP_EFTU; pfam00009
956483000488	Switch I region; other site
956483000489	G2 box; other site
956483000490	G3 box; other site
956483000491	Switch II region; other site
956483000492	G4 box; other site
956483000493	G5 box; other site
956483000494	pyruvate kinase; Provisional; Region: PRK05826
956483000495	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
956483000496	domain interfaces; other site
956483000497	active site
956483000498	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
956483000499	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
956483000500	nucleotide binding site [chemical binding]; other site
956483000501	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
956483000502	Glucose inhibited division protein A; Region: GIDA; pfam01134
956483000503	(R)-2-Hydroxyglutarate Dehydrogenase and related dehydrogenases, NAD-binding and catalytic domains; Region: HGDH_like; cd12184
956483000504	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
956483000505	putative homodimer interface [polypeptide binding]; other site
956483000506	putative ligand binding site [chemical binding]; other site
956483000507	putative NAD binding site [chemical binding]; other site
956483000508	catalytic site [active]
956483000509	potential frameshift: common BLAST hit: gi|313678283|ref|YP_004056023.1| lipase/esterase LIP3/BchO family
956483000510	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
956483000511	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
956483000512	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
956483000513	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
956483000514	DNA methylase; Region: N6_N4_Mtase; pfam01555
956483000515	DNA methylase; Region: N6_N4_Mtase; cl17433
956483000516	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
956483000517	DNA methylase; Region: N6_N4_Mtase; cl17433
956483000518	DNA methylase; Region: N6_N4_Mtase; cl17433
956483000519	trigger factor; Region: tig; TIGR00115
956483000520	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
956483000521	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
956483000522	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483000523	Integrase core domain; Region: rve; pfam00665
956483000524	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
956483000525	active site
956483000526	catalytic residues [active]
956483000527	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
956483000528	5'-3' exonuclease; Provisional; Region: PRK14976
956483000529	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
956483000530	active site
956483000531	metal binding site 1 [ion binding]; metal-binding site
956483000532	putative 5' ssDNA interaction site; other site
956483000533	metal binding site 3; metal-binding site
956483000534	metal binding site 2 [ion binding]; metal-binding site
956483000535	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
956483000536	putative DNA binding site [nucleotide binding]; other site
956483000537	putative metal binding site [ion binding]; other site
956483000538	DNA polymerase III DnaE; Validated; Region: dnaE; PRK07135
956483000539	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
956483000540	active site
956483000541	PHP Thumb interface [polypeptide binding]; other site
956483000542	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
956483000543	active site
956483000544	catalytic residues [active]
956483000545	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
956483000546	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
956483000547	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
956483000548	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
956483000549	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
956483000550	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
956483000551	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
956483000552	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
956483000553	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
956483000554	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
956483000555	S-adenosylmethionine binding site [chemical binding]; other site
956483000556	Polypeptide deformylase; Region: Pep_deformylase; pfam01327
956483000557	active site
956483000558	catalytic residues [active]
956483000559	metal binding site [ion binding]; metal-binding site
956483000560	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit [DNA replication, recombination, and repair]; Region: GyrB; COG0187
956483000561	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
956483000562	Mg2+ binding site [ion binding]; other site
956483000563	G-X-G motif; other site
956483000564	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
956483000565	anchoring element; other site
956483000566	dimer interface [polypeptide binding]; other site
956483000567	ATP binding site [chemical binding]; other site
956483000568	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
956483000569	active site
956483000570	metal binding site [ion binding]; metal-binding site
956483000571	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
956483000572	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
956483000573	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
956483000574	CAP-like domain; other site
956483000575	active site
956483000576	primary dimer interface [polypeptide binding]; other site
956483000577	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
956483000578	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
956483000579	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
956483000580	active site
956483000581	motif I; other site
956483000582	motif II; other site
956483000583	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
956483000584	Ribonuclease HIII [DNA replication, recombination, and repair]; Region: RnhC; COG1039
956483000585	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
956483000586	RNA/DNA hybrid binding site [nucleotide binding]; other site
956483000587	active site
956483000588	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
956483000589	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
956483000590	cofactor binding site; other site
956483000591	DNA binding site [nucleotide binding]
956483000592	substrate interaction site [chemical binding]; other site
956483000593	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
956483000594	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; cl17726
956483000595	potential frameshift: common BLAST hit: gi|313678806|ref|YP_004056546.1| ISMbov1, transposase
956483000596	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483000597	Integrase core domain; Region: rve; pfam00665
956483000598	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
956483000599	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
956483000600	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
956483000601	active site
956483000602	Endonuclease I; Region: Endonuclease_1; cl01003
956483000603	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
956483000604	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
956483000605	TPP-binding site [chemical binding]; other site
956483000606	dimer interface [polypeptide binding]; other site
956483000607	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
956483000608	PYR/PP interface [polypeptide binding]; other site
956483000609	dimer interface [polypeptide binding]; other site
956483000610	TPP binding site [chemical binding]; other site
956483000611	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
956483000612	inorganic pyrophosphatase; Provisional; Region: PRK02230
956483000613	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
956483000614	dimer interface [polypeptide binding]; other site
956483000615	substrate binding site [chemical binding]; other site
956483000616	metal binding sites [ion binding]; metal-binding site
956483000617	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
956483000618	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
956483000619	nucleotide binding site/active site [active]
956483000620	HIT family signature motif; other site
956483000621	catalytic residue [active]
956483000622	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
956483000623	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
956483000624	dimer interface [polypeptide binding]; other site
956483000625	catalytic triad [active]
956483000626	peroxidatic and resolving cysteines [active]
956483000627	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
956483000628	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
956483000629	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
956483000630	P loop; other site
956483000631	GTP binding site [chemical binding]; other site
956483000632	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
956483000633	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
956483000634	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
956483000635	active site
956483000636	HIGH motif; other site
956483000637	KMSKS motif; other site
956483000638	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
956483000639	tRNA binding surface [nucleotide binding]; other site
956483000640	anticodon binding site; other site
956483000641	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
956483000642	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
956483000643	S-adenosylmethionine binding site [chemical binding]; other site
956483000644	ribonuclease R; Region: RNase_R; TIGR02063
956483000645	RNB domain; Region: RNB; pfam00773
956483000646	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
956483000647	RNA binding site [nucleotide binding]; other site
956483000648	protein translocase, SecG subunit; Region: secG; TIGR00810
956483000649	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
956483000650	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
956483000651	catalytic site [active]
956483000652	G-X2-G-X-G-K; other site
956483000653	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
956483000654	active site
956483000655	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
956483000656	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
956483000657	active site
956483000658	ATP binding site [chemical binding]; other site
956483000659	substrate binding site [chemical binding]; other site
956483000660	activation loop (A-loop); other site
956483000661	Predicted GTPases [General function prediction only]; Region: COG1162
956483000662	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
956483000663	RNA binding site [nucleotide binding]; other site
956483000664	homodimer interface [polypeptide binding]; other site
956483000665	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
956483000666	GTPase/Zn-binding domain interface [polypeptide binding]; other site
956483000667	GTP/Mg2+ binding site [chemical binding]; other site
956483000668	G4 box; other site
956483000669	G5 box; other site
956483000670	G1 box; other site
956483000671	Switch I region; other site
956483000672	G2 box; other site
956483000673	G3 box; other site
956483000674	Switch II region; other site
956483000675	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
956483000676	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
956483000677	substrate binding site [chemical binding]; other site
956483000678	hexamer interface [polypeptide binding]; other site
956483000679	metal binding site [ion binding]; metal-binding site
956483000680	AAA domain; Region: AAA_30; pfam13604
956483000681	Family description; Region: UvrD_C_2; pfam13538
956483000682	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
956483000683	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
956483000684	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483000685	Walker A motif; other site
956483000686	ATP binding site [chemical binding]; other site
956483000687	Walker B motif; other site
956483000688	arginine finger; other site
956483000689	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
956483000690	active site
956483000691	catalytic triad [active]
956483000692	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
956483000693	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
956483000694	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
956483000695	ATP binding site [chemical binding]; other site
956483000696	putative Mg++ binding site [ion binding]; other site
956483000697	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
956483000698	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
956483000699	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
956483000700	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
956483000701	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
956483000702	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
956483000703	active site
956483000704	DNA binding site [nucleotide binding]
956483000705	Int/Topo IB signature motif; other site
956483000706	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
956483000707	CTP synthetase; Validated; Region: pyrG; PRK05380
956483000708	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
956483000709	Catalytic site [active]
956483000710	active site
956483000711	UTP binding site [chemical binding]; other site
956483000712	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
956483000713	active site
956483000714	putative oxyanion hole; other site
956483000715	catalytic triad [active]
956483000716	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
956483000717	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
956483000718	active site
956483000719	HIGH motif; other site
956483000720	nucleotide binding site [chemical binding]; other site
956483000721	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
956483000722	active site
956483000723	KMSKS motif; other site
956483000724	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
956483000725	tRNA binding surface [nucleotide binding]; other site
956483000726	anticodon binding site; other site
956483000727	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
956483000728	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
956483000729	Putative mycoplasma lipoprotein, C-terminal region; Region: Lipoprotein_10; pfam03202
956483000730	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
956483000731	RuvA N terminal domain; Region: RuvA_N; pfam01330
956483000732	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
956483000733	Holliday junction DNA helicase, RuvB subunit; Region: ruvB; TIGR00635
956483000734	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483000735	Walker A motif; other site
956483000736	ATP binding site [chemical binding]; other site
956483000737	Walker B motif; other site
956483000738	arginine finger; other site
956483000739	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
956483000740	Protein export membrane protein; Region: SecD_SecF; cl14618
956483000741	Protein export membrane protein; Region: SecD_SecF; cl14618
956483000742	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02193
956483000743	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
956483000744	RNA binding site [nucleotide binding]; other site
956483000745	active site
956483000746	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
956483000747	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
956483000748	active site
956483000749	motif I; other site
956483000750	motif II; other site
956483000751	hypothetical protein; Provisional; Region: PRK07143
956483000752	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
956483000753	active site
956483000754	nucleotide binding site [chemical binding]; other site
956483000755	HIGH motif; other site
956483000756	KMSKS motif; other site
956483000757	Riboflavin kinase; Region: Flavokinase; cl03312
956483000758	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
956483000759	16S/18S rRNA binding site [nucleotide binding]; other site
956483000760	S13e-L30e interaction site [polypeptide binding]; other site
956483000761	25S rRNA binding site [nucleotide binding]; other site
956483000762	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
956483000763	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
956483000764	nucleophilic elbow; other site
956483000765	catalytic triad; other site
956483000766	potential frameshift: common BLAST hit: gi|148377497|ref|YP_001256373.1| glycerol ABC transporter, ATP-bindingcomponent
956483000767	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000768	Walker A/P-loop; other site
956483000769	ATP binding site [chemical binding]; other site
956483000770	Q-loop/lid; other site
956483000771	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
956483000772	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000773	ABC transporter signature motif; other site
956483000774	Walker B; other site
956483000775	D-loop; other site
956483000776	H-loop/switch region; other site
956483000777	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000778	dimer interface [polypeptide binding]; other site
956483000779	conserved gate region; other site
956483000780	ABC-ATPase subunit interface; other site
956483000781	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
956483000782	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
956483000783	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
956483000784	DHH family; Region: DHH; pfam01368
956483000785	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
956483000786	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
956483000787	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
956483000788	replicative DNA helicase; Region: DnaB; TIGR00665
956483000789	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
956483000790	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
956483000791	Walker A motif; other site
956483000792	ATP binding site [chemical binding]; other site
956483000793	Walker B motif; other site
956483000794	DNA binding loops [nucleotide binding]
956483000795	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
956483000796	Domain of unknown function DUF21; Region: DUF21; pfam01595
956483000797	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
956483000798	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
956483000799	HTH-like domain; Region: HTH_21; pfam13276
956483000800	Integrase core domain; Region: rve; pfam00665
956483000801	Integrase core domain; Region: rve_3; cl15866
956483000802	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
956483000803	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
956483000804	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
956483000805	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
956483000806	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
956483000807	Protein of unknown function (DUF1168); Region: DUF1168; pfam06658
956483000808	RmuC family; Region: RmuC; pfam02646
956483000809	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
956483000810	Active site serine [active]
956483000811	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
956483000812	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
956483000813	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
956483000814	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
956483000815	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
956483000816	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
956483000817	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
956483000818	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
956483000819	rRNA interaction site [nucleotide binding]; other site
956483000820	S8 interaction site; other site
956483000821	putative laminin-1 binding site; other site
956483000822	elongation factor Ts; Provisional; Region: tsf; PRK09377
956483000823	UBA/TS-N domain; Region: UBA; pfam00627
956483000824	Elongation factor TS; Region: EF_TS; pfam00889
956483000825	Elongation factor TS; Region: EF_TS; pfam00889
956483000826	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
956483000827	Active site serine [active]
956483000828	dUTPase; Region: dUTPase_2; pfam08761
956483000829	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527
956483000830	active site
956483000831	homodimer interface [polypeptide binding]; other site
956483000832	metal binding site [ion binding]; metal-binding site
956483000833	Transposase [DNA replication, recombination, and repair]; Region: COG5421
956483000834	Archaeal putative transposase ISC1217; Region: DDE_Tnp_2; pfam04693
956483000835	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
956483000836	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
956483000837	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
956483000838	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
956483000839	Uncharacterized conserved protein [Function unknown]; Region: COG0327
956483000840	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
956483000841	RNA polymerase sigma factor; Provisional; Region: PRK05901
956483000842	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
956483000843	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
956483000844	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
956483000845	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
956483000846	DNA binding residues [nucleotide binding]
956483000847	DNA primase, catalytic core; Region: dnaG; TIGR01391
956483000848	CHC2 zinc finger; Region: zf-CHC2; cl17510
956483000849	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
956483000850	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
956483000851	active site
956483000852	metal binding site [ion binding]; metal-binding site
956483000853	interdomain interaction site; other site
956483000854	glycyl-tRNA synthetase; Provisional; Region: PRK04173
956483000855	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
956483000856	motif 1; other site
956483000857	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
956483000858	active site
956483000859	motif 2; other site
956483000860	motif 3; other site
956483000861	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
956483000862	anticodon binding site; other site
956483000863	High affinity transport system protein p37; Region: Mycoplasma_p37; pfam06646
956483000864	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
956483000865	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000866	Walker A/P-loop; other site
956483000867	ATP binding site [chemical binding]; other site
956483000868	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483000869	Q-loop/lid; other site
956483000870	ABC transporter signature motif; other site
956483000871	Walker B; other site
956483000872	D-loop; other site
956483000873	H-loop/switch region; other site
956483000874	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000875	dimer interface [polypeptide binding]; other site
956483000876	conserved gate region; other site
956483000877	putative PBP binding loops; other site
956483000878	ABC-ATPase subunit interface; other site
956483000879	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
956483000880	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483000881	dimer interface [polypeptide binding]; other site
956483000882	conserved gate region; other site
956483000883	putative PBP binding loops; other site
956483000884	ABC-ATPase subunit interface; other site
956483000885	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
956483000886	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12903
956483000887	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
956483000888	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
956483000889	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH2; cd08286
956483000890	catalytic Zn binding site [ion binding]; other site
956483000891	structural Zn binding site [ion binding]; other site
956483000892	NAD(P) binding site [chemical binding]; other site
956483000893	DNA topoisomerase I; Validated; Region: PRK05582
956483000894	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
956483000895	active site
956483000896	interdomain interaction site; other site
956483000897	putative metal-binding site [ion binding]; other site
956483000898	nucleotide binding site [chemical binding]; other site
956483000899	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
956483000900	domain I; other site
956483000901	DNA binding groove [nucleotide binding]
956483000902	phosphate binding site [ion binding]; other site
956483000903	domain II; other site
956483000904	domain III; other site
956483000905	nucleotide binding site [chemical binding]; other site
956483000906	catalytic site [active]
956483000907	domain IV; other site
956483000908	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
956483000909	Ribosomal protein S6; Region: Ribosomal_S6; pfam01250
956483000910	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
956483000911	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
956483000912	dimer interface [polypeptide binding]; other site
956483000913	ssDNA binding site [nucleotide binding]; other site
956483000914	tetramer (dimer of dimers) interface [polypeptide binding]; other site
956483000915	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
956483000916	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483000917	Integrase core domain; Region: rve; pfam00665
956483000918	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
956483000919	Amino acid permease; Region: AA_permease_2; pfam13520
956483000920	histidyl-tRNA synthetase; Region: hisS; TIGR00442
956483000921	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
956483000922	dimer interface [polypeptide binding]; other site
956483000923	motif 1; other site
956483000924	active site
956483000925	motif 2; other site
956483000926	motif 3; other site
956483000927	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
956483000928	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
956483000929	dimer interface [polypeptide binding]; other site
956483000930	anticodon binding site; other site
956483000931	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
956483000932	homodimer interface [polypeptide binding]; other site
956483000933	motif 1; other site
956483000934	active site
956483000935	motif 2; other site
956483000936	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
956483000937	active site
956483000938	motif 3; other site
956483000939	HTH-like domain; Region: HTH_21; pfam13276
956483000940	Integrase core domain; Region: rve; pfam00665
956483000941	Integrase core domain; Region: rve_3; cl15866
956483000942	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
956483000943	amphipathic channel; other site
956483000944	Asn-Pro-Ala signature motifs; other site
956483000945	glycerol kinase; Provisional; Region: glpK; PRK00047
956483000946	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
956483000947	N- and C-terminal domain interface [polypeptide binding]; other site
956483000948	active site
956483000949	MgATP binding site [chemical binding]; other site
956483000950	catalytic site [active]
956483000951	metal binding site [ion binding]; metal-binding site
956483000952	glycerol binding site [chemical binding]; other site
956483000953	homotetramer interface [polypeptide binding]; other site
956483000954	homodimer interface [polypeptide binding]; other site
956483000955	FBP binding site [chemical binding]; other site
956483000956	protein IIAGlc interface [polypeptide binding]; other site
956483000957	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; cl17236
956483000958	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
956483000959	DHH family; Region: DHH; pfam01368
956483000960	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
956483000961	DHH family; Region: DHH; pfam01368
956483000962	DHHA1 domain; Region: DHHA1; pfam02272
956483000963	Recombination protein O N terminal; Region: RecO_N; pfam11967
956483000964	DNA repair protein RecO; Region: reco; TIGR00613
956483000965	Recombination protein O C terminal; Region: RecO_C; pfam02565
956483000966	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
956483000967	DAK2 domain; Region: Dak2; pfam02734
956483000968	putative phosphate acyltransferase; Provisional; Region: PRK05331
956483000969	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
956483000970	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
956483000971	dimerization interface [polypeptide binding]; other site
956483000972	active site
956483000973	metal binding site [ion binding]; metal-binding site
956483000974	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
956483000975	dsRNA binding site [nucleotide binding]; other site
956483000976	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
956483000977	AAA domain; Region: AAA_23; pfam13476
956483000978	Walker A/P-loop; other site
956483000979	ATP binding site [chemical binding]; other site
956483000980	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
956483000981	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
956483000982	ABC transporter signature motif; other site
956483000983	Walker B; other site
956483000984	D-loop; other site
956483000985	H-loop/switch region; other site
956483000986	Uncharacterized conserved protein [Function unknown]; Region: COG1284
956483000987	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
956483000988	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
956483000989	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
956483000990	active site
956483000991	motif I; other site
956483000992	motif II; other site
956483000993	DNA protecting protein DprA; Region: dprA; TIGR00732
956483000994	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
956483000995	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
956483000996	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
956483000997	NAD binding site [chemical binding]; other site
956483000998	substrate binding site [chemical binding]; other site
956483000999	catalytic Zn binding site [ion binding]; other site
956483001000	tetramer interface [polypeptide binding]; other site
956483001001	structural Zn binding site [ion binding]; other site
956483001002	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
956483001003	active site
956483001004	potential frameshift: common BLAST hit: gi|291320574|ref|YP_003515838.1| aminopeptidase
956483001005	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
956483001006	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
956483001007	potential frameshift: common BLAST hit: gi|313678750|ref|YP_004056490.1| ISMbov5, transposase
956483001008	potential frameshift: common BLAST hit: gi|313678750|ref|YP_004056490.1| ISMbov5, transposase
956483001009	potential frameshift: common BLAST hit: gi|313678750|ref|YP_004056490.1| ISMbov5, transposase
956483001010	Fumarate hydratase (Fumerase); Region: Fumerase; cl00851
956483001011	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483001012	Integrase core domain; Region: rve; pfam00665
956483001013	Putative peptidase (DUF31); Region: DUF31; pfam01732
956483001014	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
956483001015	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
956483001016	NAD binding site [chemical binding]; other site
956483001017	substrate binding site [chemical binding]; other site
956483001018	catalytic Zn binding site [ion binding]; other site
956483001019	tetramer interface [polypeptide binding]; other site
956483001020	structural Zn binding site [ion binding]; other site
956483001021	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
956483001022	DNA binding site [nucleotide binding]
956483001023	substrate interaction site [chemical binding]; other site
956483001024	potential frameshift: common BLAST hit: gi|148377689|ref|YP_001256565.1| lipoprotein
956483001025	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
956483001026	potential frameshift: common BLAST hit: gi|313678806|ref|YP_004056546.1| ISMbov1, transposase
956483001027	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483001028	Integrase core domain; Region: rve; pfam00665
956483001029	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001030	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
956483001031	DEAD-like helicases superfamily; Region: DEXDc; smart00487
956483001032	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
956483001033	Walker A motif; other site
956483001034	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
956483001035	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
956483001036	active site
956483001037	catalytic site [active]
956483001038	substrate binding site [chemical binding]; other site
956483001039	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
956483001040	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
956483001041	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
956483001042	Ligand Binding Site [chemical binding]; other site
956483001043	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
956483001044	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
956483001045	motif 1; other site
956483001046	active site
956483001047	motif 2; other site
956483001048	motif 3; other site
956483001049	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
956483001050	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
956483001051	Putative peptidase (DUF31); Region: DUF31; pfam01732
956483001052	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
956483001053	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
956483001054	NAD(P) binding site [chemical binding]; other site
956483001055	active site
956483001056	Uncharacterized phage-associated protein [Function unknown]; Region: GepA; COG3600
956483001057	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001058	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
956483001059	potential frameshift: common BLAST hit: gi|313678587|ref|YP_004056327.1| membrane protein
956483001060	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
956483001061	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
956483001062	ATP binding site [chemical binding]; other site
956483001063	Walker B motif; other site
956483001064	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
956483001065	ssDNA binding site [nucleotide binding]; other site
956483001066	dimer interface [polypeptide binding]; other site
956483001067	tetramer (dimer of dimers) interface [polypeptide binding]; other site
956483001068	potential frameshift: common BLAST hit: gi|313678576|ref|YP_004056316.1| TraE family protein
956483001069	AAA-like domain; Region: AAA_10; pfam12846
956483001070	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
956483001071	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
956483001072	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
956483001073	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
956483001074	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
956483001075	active site
956483001076	GTP-binding protein YchF; Reviewed; Region: PRK09601
956483001077	YchF GTPase; Region: YchF; cd01900
956483001078	G1 box; other site
956483001079	GTP/Mg2+ binding site [chemical binding]; other site
956483001080	Switch I region; other site
956483001081	G2 box; other site
956483001082	Switch II region; other site
956483001083	G3 box; other site
956483001084	G4 box; other site
956483001085	G5 box; other site
956483001086	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
956483001087	Protein of unknown function DUF45; Region: DUF45; cl00636
956483001088	Nuclease-related domain; Region: NERD; pfam08378
956483001089	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
956483001090	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
956483001091	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
956483001092	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
956483001093	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
956483001094	excinuclease ABC subunit B; Provisional; Region: PRK05298
956483001095	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
956483001096	ATP binding site [chemical binding]; other site
956483001097	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
956483001098	nucleotide binding region [chemical binding]; other site
956483001099	ATP-binding site [chemical binding]; other site
956483001100	Ultra-violet resistance protein B; Region: UvrB; pfam12344
956483001101	UvrB/uvrC motif; Region: UVR; pfam02151
956483001102	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
956483001103	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
956483001104	cofactor binding site; other site
956483001105	DNA binding site [nucleotide binding]
956483001106	substrate interaction site [chemical binding]; other site
956483001107	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
956483001108	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
956483001109	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
956483001110	TrkA-N domain; Region: TrkA_N; pfam02254
956483001111	TrkA-C domain; Region: TrkA_C; pfam02080
956483001112	cell division protein MraZ; Reviewed; Region: PRK00326
956483001113	MraZ protein; Region: MraZ; pfam02381
956483001114	MraZ protein; Region: MraZ; pfam02381
956483001115	MraW methylase family; Region: Methyltransf_5; cl17771
956483001116	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
956483001117	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
956483001118	nucleotide binding site [chemical binding]; other site
956483001119	SulA interaction site; other site
956483001120	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
956483001121	lipoyl-biotinyl attachment site [posttranslational modification]; other site
956483001122	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
956483001123	RNA methyltransferase, RsmE family; Region: TIGR00046
956483001124	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
956483001125	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
956483001126	active site
956483001127	Zn binding site [ion binding]; other site
956483001128	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
956483001129	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
956483001130	dimer interface [polypeptide binding]; other site
956483001131	ssDNA binding site [nucleotide binding]; other site
956483001132	tetramer (dimer of dimers) interface [polypeptide binding]; other site
956483001133	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
956483001134	active site
956483001135	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
956483001136	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
956483001137	HIGH motif; other site
956483001138	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
956483001139	active site
956483001140	KMSKS motif; other site
956483001141	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
956483001142	tRNA binding surface [nucleotide binding]; other site
956483001143	anticodon binding site; other site
956483001144	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483001145	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
956483001146	Walker A motif; other site
956483001147	ATP binding site [chemical binding]; other site
956483001148	Walker B motif; other site
956483001149	arginine finger; other site
956483001150	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
956483001151	membrane protein; Provisional; Region: PRK14418
956483001152	F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) [Energy production and conversion]; Region: AtpC; COG0355
956483001153	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
956483001154	gamma subunit interface [polypeptide binding]; other site
956483001155	epsilon subunit interface [polypeptide binding]; other site
956483001156	LBP interface [polypeptide binding]; other site
956483001157	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
956483001158	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
956483001159	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
956483001160	alpha subunit interaction interface [polypeptide binding]; other site
956483001161	Walker A motif; other site
956483001162	ATP binding site [chemical binding]; other site
956483001163	Walker B motif; other site
956483001164	inhibitor binding site; inhibition site
956483001165	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
956483001166	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
956483001167	core domain interface [polypeptide binding]; other site
956483001168	delta subunit interface [polypeptide binding]; other site
956483001169	epsilon subunit interface [polypeptide binding]; other site
956483001170	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
956483001171	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
956483001172	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
956483001173	beta subunit interaction interface [polypeptide binding]; other site
956483001174	Walker A motif; other site
956483001175	ATP binding site [chemical binding]; other site
956483001176	Walker B motif; other site
956483001177	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
956483001178	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
956483001179	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
956483001180	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
956483001181	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
956483001182	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
956483001183	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
956483001184	potential frameshift: common BLAST hit: gi|313678806|ref|YP_004056546.1| ISMbov1, transposase
956483001185	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483001186	Integrase core domain; Region: rve; pfam00665
956483001187	Mycoplasma P30 protein; Region: P30; pfam07390
956483001188	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
956483001189	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
956483001190	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
956483001191	active site
956483001192	dimer interface [polypeptide binding]; other site
956483001193	motif 1; other site
956483001194	motif 2; other site
956483001195	motif 3; other site
956483001196	HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for...; Region: HGTP_anticodon; cl00266
956483001197	anticodon binding site; other site
956483001198	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
956483001199	active site
956483001200	HIGH motif; other site
956483001201	dimer interface [polypeptide binding]; other site
956483001202	KMSKS motif; other site
956483001203	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
956483001204	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
956483001205	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001206	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001207	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001208	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001209	Putative peptidase (DUF31); Region: DUF31; pfam01732
956483001210	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
956483001211	AAA domain; Region: AAA_14; pfam13173
956483001212	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
956483001213	Active site serine [active]
956483001214	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001215	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001216	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
956483001217	active site turn [active]
956483001218	phosphorylation site [posttranslational modification]
956483001219	UGMP family protein; Validated; Region: PRK09604
956483001220	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
956483001221	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
956483001222	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
956483001223	elongation factor Tu; Reviewed; Region: PRK12736
956483001224	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
956483001225	G1 box; other site
956483001226	GEF interaction site [polypeptide binding]; other site
956483001227	GTP/Mg2+ binding site [chemical binding]; other site
956483001228	Switch I region; other site
956483001229	G2 box; other site
956483001230	G3 box; other site
956483001231	Switch II region; other site
956483001232	G4 box; other site
956483001233	G5 box; other site
956483001234	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
956483001235	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
956483001236	Antibiotic Binding Site [chemical binding]; other site
956483001237	enolase; Provisional; Region: eno; PRK00077
956483001238	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
956483001239	dimer interface [polypeptide binding]; other site
956483001240	metal binding site [ion binding]; metal-binding site
956483001241	substrate binding pocket [chemical binding]; other site
956483001242	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
956483001243	RNA binding site [nucleotide binding]; other site
956483001244	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
956483001245	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
956483001246	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
956483001247	active site
956483001248	dimer interface [polypeptide binding]; other site
956483001249	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
956483001250	dimer interface [polypeptide binding]; other site
956483001251	active site
956483001252	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
956483001253	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
956483001254	DNA binding site [nucleotide binding]
956483001255	catalytic residue [active]
956483001256	H2TH interface [polypeptide binding]; other site
956483001257	putative catalytic residues [active]
956483001258	turnover-facilitating residue; other site
956483001259	intercalation triad [nucleotide binding]; other site
956483001260	8OG recognition residue [nucleotide binding]; other site
956483001261	putative reading head residues; other site
956483001262	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
956483001263	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
956483001264	Smr domain; Region: Smr; pfam01713
956483001265	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
956483001266	SelR domain; Region: SelR; pfam01641
956483001267	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
956483001268	Putative peptidase (DUF31); Region: DUF31; pfam01732
956483001269	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
956483001270	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
956483001271	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483001272	Walker A/P-loop; other site
956483001273	ATP binding site [chemical binding]; other site
956483001274	Q-loop/lid; other site
956483001275	ABC transporter signature motif; other site
956483001276	Walker B; other site
956483001277	D-loop; other site
956483001278	H-loop/switch region; other site
956483001279	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
956483001280	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
956483001281	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483001282	Walker A/P-loop; other site
956483001283	ATP binding site [chemical binding]; other site
956483001284	Q-loop/lid; other site
956483001285	ABC transporter signature motif; other site
956483001286	Walker B; other site
956483001287	D-loop; other site
956483001288	H-loop/switch region; other site
956483001289	elongation factor P; Validated; Region: PRK00529
956483001290	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
956483001291	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
956483001292	RNA binding site [nucleotide binding]; other site
956483001293	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
956483001294	RNA binding site [nucleotide binding]; other site
956483001295	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
956483001296	MgtE intracellular N domain; Region: MgtE_N; pfam03448
956483001297	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
956483001298	Divalent cation transporter; Region: MgtE; cl00786
956483001299	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
956483001300	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
956483001301	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
956483001302	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
956483001303	putative dimer interface [polypeptide binding]; other site
956483001304	putative anticodon binding site; other site
956483001305	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
956483001306	motif 1; other site
956483001307	dimer interface [polypeptide binding]; other site
956483001308	active site
956483001309	motif 2; other site
956483001310	motif 3; other site
956483001311	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
956483001312	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
956483001313	Part of AAA domain; Region: AAA_19; pfam13245
956483001314	Family description; Region: UvrD_C_2; pfam13538
956483001315	S4 domain; Region: S4_2; cl17325
956483001316	EDD domain protein, DegV family; Region: DegV; TIGR00762
956483001317	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
956483001318	Putative peptidase (DUF31); Region: DUF31; pfam01732
956483001319	potential frameshift: common BLAST hit: gi|313678480|ref|YP_004056220.1| lipoprotein
956483001320	F0F1 ATP synthase subunit beta; Provisional; Region: PRK12597
956483001321	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
956483001322	alpha subunit interaction interface [polypeptide binding]; other site
956483001323	Walker A motif; other site
956483001324	ATP binding site [chemical binding]; other site
956483001325	Walker B motif; other site
956483001326	inhibitor binding site; inhibition site
956483001327	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
956483001328	F0F1 ATP synthase subunit alpha; Validated; Region: PRK07165
956483001329	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
956483001330	Walker A motif; other site
956483001331	ATP binding site [chemical binding]; other site
956483001332	Walker B motif; other site
956483001333	Protein of unknown function (DUF2714); Region: DUF2714; pfam10896
956483001334	Putative peptidase (DUF31); Region: DUF31; pfam01732
956483001335	Mycoplasma virulence signal region (Myco_arth_vir_N); Region: Myco_arth_vir_N; pfam09610
956483001336	Putative peptidase (DUF31); Region: DUF31; pfam01732
956483001337	NAD-dependent DNA ligase (contains BRCT domain type II) [DNA replication, recombination, and repair]; Region: Lig; COG0272
956483001338	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
956483001339	nucleotide binding pocket [chemical binding]; other site
956483001340	K-X-D-G motif; other site
956483001341	catalytic site [active]
956483001342	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
956483001343	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
956483001344	BRCA1 C Terminus (BRCT) domain; Region: BRCT; pfam00533
956483001345	phosphopentomutase; Provisional; Region: PRK05362
956483001346	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
956483001347	Sporulation Regulator WhiA C terminal domain; Region: HTH_WhiA; pfam02650
956483001348	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001349	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
956483001350	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
956483001351	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
956483001352	cofactor binding site; other site
956483001353	DNA binding site [nucleotide binding]
956483001354	substrate interaction site [chemical binding]; other site
956483001355	Ycf1; Provisional; Region: ycf1; CHL00204
956483001356	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
956483001357	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
956483001358	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
956483001359	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
956483001360	23S rRNA interface [nucleotide binding]; other site
956483001361	L3 interface [polypeptide binding]; other site
956483001362	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
956483001363	Cupin domain; Region: Cupin_2; cl17218
956483001364	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
956483001365	active site
956483001366	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
956483001367	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
956483001368	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
956483001369	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
956483001370	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
956483001371	motif II; other site
956483001372	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
956483001373	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
956483001374	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
956483001375	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
956483001376	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
956483001377	Walker A/P-loop; other site
956483001378	ATP binding site [chemical binding]; other site
956483001379	Q-loop/lid; other site
956483001380	ABC transporter signature motif; other site
956483001381	Walker B; other site
956483001382	D-loop; other site
956483001383	H-loop/switch region; other site
956483001384	aromatic cluster surface protein; Region: aro_clust_Mycop; TIGR04313
956483001385	aromatic cluster surface protein; Region: aro_clust_Mycop; TIGR04313
956483001386	aromatic cluster surface protein; Region: aro_clust_Mycop; TIGR04313
956483001387	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
956483001388	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
956483001389	active site
956483001390	substrate binding site [chemical binding]; other site
956483001391	metal binding site [ion binding]; metal-binding site
956483001392	transcription antitermination factor NusB; Region: nusB; TIGR01951
956483001393	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
956483001394	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
956483001395	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
956483001396	dimerization domain swap beta strand [polypeptide binding]; other site
956483001397	regulatory protein interface [polypeptide binding]; other site
956483001398	active site
956483001399	regulatory phosphorylation site [posttranslational modification]; other site
956483001400	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
956483001401	dimer interface [polypeptide binding]; other site
956483001402	Binding-protein-dependent transport system inner membrane component; Region: BPD_transp_1; pfam00528
956483001403	conserved gate region; other site
956483001404	ABC-ATPase subunit interface; other site
956483001405	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
956483001406	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
956483001407	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
956483001408	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
956483001409	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
956483001410	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
956483001411	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
956483001412	23S rRNA binding site [nucleotide binding]; other site
956483001413	L21 binding site [polypeptide binding]; other site
956483001414	L13 binding site [polypeptide binding]; other site
956483001415	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
956483001416	Part of AAA domain; Region: AAA_19; pfam13245
956483001417	AAA domain; Region: AAA_12; pfam13087
956483001418	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
956483001419	active site
956483001420	ATP binding site [chemical binding]; other site
956483001421	Phosphotransferase enzyme family; Region: APH; pfam01636
956483001422	substrate binding site [chemical binding]; other site
956483001423	GTP-binding protein LepA; Provisional; Region: PRK05433
956483001424	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
956483001425	G1 box; other site
956483001426	GTP/Mg2+ binding site [chemical binding]; other site
956483001427	G2 box; other site
956483001428	Switch I region; other site
956483001429	G3 box; other site
956483001430	Switch II region; other site
956483001431	G4 box; other site
956483001432	G5 box; other site
956483001433	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
956483001434	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
956483001435	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
956483001436	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
956483001437	active site
956483001438	substrate binding site [chemical binding]; other site
956483001439	ATP binding site [chemical binding]; other site
956483001440	Phosphotransferase enzyme family; Region: APH; pfam01636
956483001441	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
956483001442	substrate binding site [chemical binding]; other site
956483001443	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
956483001444	dimer interface [polypeptide binding]; other site
956483001445	FMN binding site [chemical binding]; other site
956483001446	NADPH bind site [chemical binding]; other site
956483001447	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
956483001448	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
956483001449	Integrase core domain; Region: rve_3; cl15866
956483001450	Transposase [DNA replication, recombination, and repair]; Region: COG5421
956483001451	HTH-like domain; Region: HTH_21; pfam13276
956483001452	Integrase core domain; Region: rve; pfam00665
956483001453	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
956483001454	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
956483001455	active site
956483001456	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
956483001457	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
956483001458	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
956483001459	active site
956483001460	HIGH motif; other site
956483001461	KMSK motif region; other site
956483001462	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
956483001463	tRNA binding surface [nucleotide binding]; other site
956483001464	anticodon binding site; other site
956483001465	Membrane transport protein; Region: Mem_trans; cl09117
956483001466	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
956483001467	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
956483001468	NAD(P) binding site [chemical binding]; other site
956483001469	LDH/MDH dimer interface [polypeptide binding]; other site
956483001470	substrate binding site [chemical binding]; other site
956483001471	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
956483001472	E3 interaction surface; other site
956483001473	lipoyl attachment site [posttranslational modification]; other site
956483001474	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
956483001475	Acetokinase family; Region: Acetate_kinase; cl17229
956483001476	propionate/acetate kinase; Provisional; Region: PRK12379
956483001477	Cytotoxic; Region: Cytotoxic; pfam09000
956483001478	Major Facilitator Superfamily; Region: MFS_1; pfam07690
956483001479	Mycoplasma MFS transporter; Region: MFS_Mycoplasma; pfam07672
956483001480	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483001481	Helix-turn-helix domain; Region: HTH_38; pfam13936
956483001482	Integrase core domain; Region: rve; pfam00665
956483001483	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
956483001484	endonuclease IV; Provisional; Region: PRK01060
956483001485	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
956483001486	AP (apurinic/apyrimidinic) site pocket; other site
956483001487	DNA interaction; other site
956483001488	Metal-binding active site; metal-binding site
956483001489	Yip1 domain; Region: Yip1; pfam04893
956483001490	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
956483001491	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
956483001492	GIY-YIG motif/motif A; other site
956483001493	active site
956483001494	catalytic site [active]
956483001495	putative DNA binding site [nucleotide binding]; other site
956483001496	metal binding site [ion binding]; metal-binding site
956483001497	UvrB/uvrC motif; Region: UVR; pfam02151
956483001498	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
956483001499	Mycoplasma MG185/MG260 protein; Region: Lipoprotein_X; pfam03305
956483001500	Putative mycoplasma lipoprotein, C-terminal region; Region: Lipoprotein_10; pfam03202
956483001501	potential frameshift: common BLAST hit: gi|313678409|ref|YP_004056149.1| lipoprotein, nuclease family
956483001502	Staphylococcal nuclease homologues; Region: SNc; smart00318
956483001503	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140
956483001504	Catalytic site; other site
956483001505	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
956483001506	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483001507	Walker A/P-loop; other site
956483001508	ATP binding site [chemical binding]; other site
956483001509	Q-loop/lid; other site
956483001510	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
956483001511	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483001512	ABC transporter signature motif; other site
956483001513	Walker B; other site
956483001514	D-loop; other site
956483001515	H-loop/switch region; other site
956483001516	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483001517	dimer interface [polypeptide binding]; other site
956483001518	conserved gate region; other site
956483001519	putative PBP binding loops; other site
956483001520	ABC-ATPase subunit interface; other site
956483001521	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
956483001522	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
956483001523	dimer interface [polypeptide binding]; other site
956483001524	conserved gate region; other site
956483001525	putative PBP binding loops; other site
956483001526	ABC-ATPase subunit interface; other site
956483001527	GTPase CgtA; Reviewed; Region: obgE; PRK12297
956483001528	GTP1/OBG; Region: GTP1_OBG; pfam01018
956483001529	Obg GTPase; Region: Obg; cd01898
956483001530	G1 box; other site
956483001531	GTP/Mg2+ binding site [chemical binding]; other site
956483001532	Switch I region; other site
956483001533	G2 box; other site
956483001534	G3 box; other site
956483001535	Switch II region; other site
956483001536	G4 box; other site
956483001537	G5 box; other site
956483001538	Obg family GTPase CgtA, C-terminal extension; Region: Obg_CgtA_exten; TIGR03595
956483001539	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
956483001540	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
956483001541	active site
956483001542	motif I; other site
956483001543	motif II; other site
956483001544	Purine-nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: DeoD; COG0813
956483001545	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
956483001546	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
956483001547	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
956483001548	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
956483001549	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
956483001550	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
956483001551	intersubunit interface [polypeptide binding]; other site
956483001552	active site
956483001553	catalytic residue [active]
956483001554	triosephosphate isomerase; Provisional; Region: PRK14565
956483001555	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
956483001556	substrate binding site [chemical binding]; other site
956483001557	dimer interface [polypeptide binding]; other site
956483001558	catalytic triad [active]
956483001559	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
956483001560	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13651
956483001561	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
956483001562	Walker A/P-loop; other site
956483001563	ATP binding site [chemical binding]; other site
956483001564	Q-loop/lid; other site
956483001565	ABC transporter signature motif; other site
956483001566	Walker B; other site
956483001567	D-loop; other site
956483001568	H-loop/switch region; other site
956483001569	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13632
956483001570	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
956483001571	Walker A/P-loop; other site
956483001572	ATP binding site [chemical binding]; other site
956483001573	Q-loop/lid; other site
956483001574	ABC transporter signature motif; other site
956483001575	Walker B; other site
956483001576	D-loop; other site
956483001577	H-loop/switch region; other site
956483001578	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
956483001579	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
956483001580	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
956483001581	alphaNTD - beta interaction site [polypeptide binding]; other site
956483001582	alphaNTD homodimer interface [polypeptide binding]; other site
956483001583	alphaNTD - beta' interaction site [polypeptide binding]; other site
956483001584	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
956483001585	30S ribosomal protein S11; Validated; Region: PRK05309
956483001586	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
956483001587	30S ribosomal protein S13; Region: bact_S13; TIGR03631
956483001588	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
956483001589	rRNA binding site [nucleotide binding]; other site
956483001590	predicted 30S ribosome binding site; other site
956483001591	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
956483001592	active site
956483001593	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
956483001594	adenylate kinase; Region: adk; TIGR01351
956483001595	AMP-binding site [chemical binding]; other site
956483001596	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
956483001597	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
956483001598	SecY translocase; Region: SecY; pfam00344
956483001599	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
956483001600	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
956483001601	catalytic core [active]
956483001602	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
956483001603	HTH-like domain; Region: HTH_21; pfam13276
956483001604	Integrase core domain; Region: rve; pfam00665
956483001605	Integrase core domain; Region: rve_3; cl15866
956483001606	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
956483001607	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
956483001608	active site
956483001609	motif I; other site
956483001610	motif II; other site
956483001611	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
956483001612	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
956483001613	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
956483001614	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
956483001615	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
956483001616	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
956483001617	5S rRNA interface [nucleotide binding]; other site
956483001618	L27 interface [polypeptide binding]; other site
956483001619	23S rRNA interface [nucleotide binding]; other site
956483001620	L5 interface [polypeptide binding]; other site
956483001621	ribosomal protein L6, bacterial type; Region: L6_bact; TIGR03654
956483001622	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
956483001623	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
956483001624	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
956483001625	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
956483001626	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
956483001627	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
956483001628	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
956483001629	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
956483001630	RNA binding site [nucleotide binding]; other site
956483001631	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
956483001632	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
956483001633	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
956483001634	23S rRNA interface [nucleotide binding]; other site
956483001635	putative translocon interaction site; other site
956483001636	signal recognition particle (SRP54) interaction site; other site
956483001637	L23 interface [polypeptide binding]; other site
956483001638	trigger factor interaction site; other site
956483001639	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
956483001640	23S rRNA interface [nucleotide binding]; other site
956483001641	5S rRNA interface [nucleotide binding]; other site
956483001642	putative antibiotic binding site [chemical binding]; other site
956483001643	L25 interface [polypeptide binding]; other site
956483001644	L27 interface [polypeptide binding]; other site
956483001645	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
956483001646	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
956483001647	G-X-X-G motif; other site
956483001648	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
956483001649	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
956483001650	putative translocon binding site; other site
956483001651	protein-rRNA interface [nucleotide binding]; other site
956483001652	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
956483001653	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
956483001654	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
956483001655	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
956483001656	50S ribosomal protein L23; Reviewed; Region: rplW; PRK12280
956483001657	potential frameshift: common BLAST hit: gi|313678366|ref|YP_004056106.1| ribosomal protein, L4/L1 family
956483001658	Ribosomal protein L4/L1 family; Region: Ribosomal_L4; cl00325
956483001659	Ribosomal protein L4/L1 family; Region: Ribosomal_L4; cl00325
956483001660	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
956483001661	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
956483001662	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
956483001663	IHF dimer interface [polypeptide binding]; other site
956483001664	IHF - DNA interface [nucleotide binding]; other site
956483001665	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
956483001666	recombinase A; Provisional; Region: recA; PRK09354
956483001667	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
956483001668	hexamer interface [polypeptide binding]; other site
956483001669	Walker A motif; other site
956483001670	ATP binding site [chemical binding]; other site
956483001671	Walker B motif; other site
956483001672	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
956483001673	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
956483001674	putative active site [active]
956483001675	metal binding site [ion binding]; metal-binding site
956483001676	homodimer binding site [polypeptide binding]; other site
956483001677	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
956483001678	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
956483001679	oligomer interface [polypeptide binding]; other site
956483001680	active site
956483001681	metal binding site [ion binding]; metal-binding site
956483001682	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
956483001683	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
956483001684	active site
956483001685	uracil binding [chemical binding]; other site
956483001686	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
956483001687	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
956483001688	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
956483001689	GrpE; Region: GrpE; pfam01025
956483001690	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
956483001691	dimer interface [polypeptide binding]; other site
956483001692	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
956483001693	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
956483001694	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
956483001695	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
956483001696	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
956483001697	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
956483001698	RNA binding surface [nucleotide binding]; other site
956483001699	DNA gyrase subunit A; Validated; Region: PRK05560
956483001700	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
956483001701	CAP-like domain; other site
956483001702	active site
956483001703	primary dimer interface [polypeptide binding]; other site
956483001704	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
956483001705	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
956483001706	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
956483001707	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
956483001708	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
956483001709	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
956483001710	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
956483001711	AAA domain; Region: AAA_11; pfam13086
956483001712	Part of AAA domain; Region: AAA_19; pfam13245
956483001713	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
956483001714	AAA domain; Region: AAA_12; pfam13087
956483001715	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
956483001716	putative active site [active]
956483001717	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
956483001718	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
956483001719	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
956483001720	Int/Topo IB signature motif; other site
956483001721	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
956483001722	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
956483001723	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
956483001724	ATP binding site [chemical binding]; other site
956483001725	putative Mg++ binding site [ion binding]; other site
956483001726	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
956483001727	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
956483001728	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
956483001729	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
956483001730	HsdM N-terminal domain; Region: HsdM_N; pfam12161
956483001731	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
956483001732	Methyltransferase domain; Region: Methyltransf_26; pfam13659
956483001733	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
956483001734	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
956483001735	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
956483001736	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
956483001737	Active site serine [active]
956483001738	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
956483001739	Active site serine [active]
956483001740	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
956483001741	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
956483001742	HIGH motif; other site
956483001743	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
956483001744	active site
956483001745	KMSKS motif; other site
956483001746	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
956483001747	S-adenosylmethionine synthetase; Validated; Region: PRK05250
956483001748	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
956483001749	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
956483001750	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; pfam09529
956483001751	signal recognition particle protein; Provisional; Region: PRK10867
956483001752	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
956483001753	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
956483001754	P loop; other site
956483001755	GTP binding site [chemical binding]; other site
956483001756	Signal peptide binding domain; Region: SRP_SPB; pfam02978
956483001757	Predicted acetyltransferase [General function prediction only]; Region: COG3393
956483001758	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
956483001759	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901
956483001760	nicotinate phosphoribosyltransferase; Provisional; Region: PRK07188
956483001761	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
956483001762	active site
956483001763	Phosphoglycerate kinase; Region: PGK; pfam00162
956483001764	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
956483001765	substrate binding site [chemical binding]; other site
956483001766	hinge regions; other site
956483001767	ADP binding site [chemical binding]; other site
956483001768	catalytic site [active]
956483001769	potential frameshift: common BLAST hit: gi|313678322|ref|YP_004056062.1| peptidase, M17 family
956483001770	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cl08294
956483001771	interface (dimer of trimers) [polypeptide binding]; other site
956483001772	Substrate-binding/catalytic site; other site
956483001773	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cl08294
956483001774	Substrate-binding/catalytic site; other site
956483001775	Zn-binding sites [ion binding]; other site
956483001776	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
956483001777	putative active site [active]
956483001778	putative catalytic site [active]
956483001779	putative Mg binding site IVb [ion binding]; other site
956483001780	putative phosphate binding site [ion binding]; other site
956483001781	putative DNA binding site [nucleotide binding]; other site
956483001782	putative Mg binding site IVa [ion binding]; other site
956483001783	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
956483001784	Staphylococcus aureus SA0022 and related proteins, N-terminal metallophosphatase domain; Region: MPP_SA0022_N; cd07408
956483001785	putative active site [active]
956483001786	putative metal binding site [ion binding]; other site
956483001787	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
956483001788	elongation factor G; Reviewed; Region: PRK12739
956483001789	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
956483001790	G1 box; other site
956483001791	putative GEF interaction site [polypeptide binding]; other site
956483001792	GTP/Mg2+ binding site [chemical binding]; other site
956483001793	Switch I region; other site
956483001794	G2 box; other site
956483001795	G3 box; other site
956483001796	Switch II region; other site
956483001797	G4 box; other site
956483001798	G5 box; other site
956483001799	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
956483001800	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
956483001801	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
956483001802	30S ribosomal protein S7; Validated; Region: PRK05302
956483001803	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
956483001804	S17 interaction site [polypeptide binding]; other site
956483001805	S8 interaction site; other site
956483001806	16S rRNA interaction site [nucleotide binding]; other site
956483001807	streptomycin interaction site [chemical binding]; other site
956483001808	23S rRNA interaction site [nucleotide binding]; other site
956483001809	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
956483001810	trigger factor; Region: tig; TIGR00115
956483001811	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
956483001812	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
956483001813	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483001814	Walker A/P-loop; other site
956483001815	ATP binding site [chemical binding]; other site
956483001816	Q-loop/lid; other site
956483001817	ABC transporter signature motif; other site
956483001818	Walker B; other site
956483001819	D-loop; other site
956483001820	H-loop/switch region; other site
956483001821	ABC transporter; Region: ABC_tran_2; pfam12848
956483001822	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
956483001823	potential frameshift: common BLAST hit: gi|313678750|ref|YP_004056490.1| ISMbov5, transposase
956483001824	potential frameshift: common BLAST hit: gi|313678750|ref|YP_004056490.1| ISMbov5, transposase
956483001825	potential frameshift: common BLAST hit: gi|313678750|ref|YP_004056490.1| ISMbov5, transposase
956483001826	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
956483001827	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
956483001828	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
956483001829	Walker A/P-loop; other site
956483001830	ATP binding site [chemical binding]; other site
956483001831	Q-loop/lid; other site
956483001832	ABC transporter signature motif; other site
956483001833	Walker B; other site
956483001834	D-loop; other site
956483001835	H-loop/switch region; other site
956483001836	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
956483001837	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
956483001838	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483001839	Walker A/P-loop; other site
956483001840	ATP binding site [chemical binding]; other site
956483001841	Q-loop/lid; other site
956483001842	ABC transporter signature motif; other site
956483001843	Walker B; other site
956483001844	D-loop; other site
956483001845	H-loop/switch region; other site
956483001846	hypothetical protein; Provisional; Region: PRK00523
956483001847	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
956483001848	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
956483001849	oligomer interface [polypeptide binding]; other site
956483001850	active site
956483001851	metal binding site [ion binding]; metal-binding site
956483001852	HTH-like domain; Region: HTH_21; pfam13276
956483001853	Integrase core domain; Region: rve; pfam00665
956483001854	Integrase core domain; Region: rve_3; cl15866
956483001855	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
956483001856	RNA polymerase beta' subunit; Region: rpoC1; CHL00018
956483001857	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
956483001858	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
956483001859	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
956483001860	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
956483001861	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
956483001862	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
956483001863	DNA binding site [nucleotide binding]
956483001864	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
956483001865	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
956483001866	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
956483001867	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
956483001868	RPB1 interaction site [polypeptide binding]; other site
956483001869	RPB10 interaction site [polypeptide binding]; other site
956483001870	RPB11 interaction site [polypeptide binding]; other site
956483001871	RPB3 interaction site [polypeptide binding]; other site
956483001872	RPB12 interaction site [polypeptide binding]; other site
956483001873	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
956483001874	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
956483001875	core dimer interface [polypeptide binding]; other site
956483001876	peripheral dimer interface [polypeptide binding]; other site
956483001877	L10 interface [polypeptide binding]; other site
956483001878	L11 interface [polypeptide binding]; other site
956483001879	putative EF-Tu interaction site [polypeptide binding]; other site
956483001880	putative EF-G interaction site [polypeptide binding]; other site
956483001881	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
956483001882	23S rRNA interface [nucleotide binding]; other site
956483001883	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
956483001884	Leucine rich repeat; Region: LRR_8; pfam13855
956483001885	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
956483001886	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
956483001887	dimer interface [polypeptide binding]; other site
956483001888	putative anticodon binding site; other site
956483001889	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
956483001890	motif 1; other site
956483001891	active site
956483001892	motif 2; other site
956483001893	motif 3; other site
956483001894	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
956483001895	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
956483001896	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
956483001897	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
956483001898	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
956483001899	RNA binding site [nucleotide binding]; other site
956483001900	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483001901	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
956483001902	Walker A motif; other site
956483001903	ATP binding site [chemical binding]; other site
956483001904	Walker B motif; other site
956483001905	arginine finger; other site
956483001906	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483001907	Walker A motif; other site
956483001908	ATP binding site [chemical binding]; other site
956483001909	Walker B motif; other site
956483001910	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
956483001911	AlwI restriction endonuclease; Region: RE_AlwI; pfam09491
956483001912	HTH-like domain; Region: HTH_21; pfam13276
956483001913	Integrase core domain; Region: rve; pfam00665
956483001914	Integrase core domain; Region: rve_3; cl15866
956483001915	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
956483001916	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
956483001917	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
956483001918	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
956483001919	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
956483001920	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
956483001921	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
956483001922	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
956483001923	putative active site [active]
956483001924	substrate binding site [chemical binding]; other site
956483001925	putative cosubstrate binding site; other site
956483001926	catalytic site [active]
956483001927	Formyl transferase, C-terminal domain; Region: Formyl_trans_C; pfam02911
956483001928	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
956483001929	metal binding site [ion binding]; metal-binding site
956483001930	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
956483001931	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
956483001932	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
956483001933	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
956483001934	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
956483001935	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
956483001936	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
956483001937	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
956483001938	putative active site [active]
956483001939	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
956483001940	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
956483001941	intersubunit interface [polypeptide binding]; other site
956483001942	active site
956483001943	Zn2+ binding site [ion binding]; other site
956483001944	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
956483001945	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
956483001946	AP (apurinic/apyrimidinic) site pocket; other site
956483001947	DNA interaction; other site
956483001948	Metal-binding active site; metal-binding site
956483001949	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
956483001950	active site
956483001951	dimer interface [polypeptide binding]; other site
956483001952	magnesium binding site [ion binding]; other site
956483001953	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
956483001954	active site
956483001955	phosphorylation site [posttranslational modification]
956483001956	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
956483001957	active site
956483001958	P-loop; other site
956483001959	phosphorylation site [posttranslational modification]
956483001960	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
956483001961	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
956483001962	active site
956483001963	substrate binding pocket [chemical binding]; other site
956483001964	homodimer interaction site [polypeptide binding]; other site
956483001965	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
956483001966	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
956483001967	active site
956483001968	motif I; other site
956483001969	motif II; other site
956483001970	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
956483001971	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
956483001972	cofactor binding site; other site
956483001973	DNA binding site [nucleotide binding]
956483001974	substrate interaction site [chemical binding]; other site
956483001975	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
956483001976	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
956483001977	DNA methylase; Region: N6_N4_Mtase; pfam01555
956483001978	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001979	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483001980	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
956483001981	Fic family protein [Function unknown]; Region: COG3177
956483001982	Fic/DOC family; Region: Fic; pfam02661
956483001983	potential frameshift: common BLAST hit: gi|15828868|ref|NP_326228.1| type III restriction-modification system: methylase
956483001984	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
956483001985	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
956483001986	DNA methylase; Region: N6_N4_Mtase; pfam01555
956483001987	DNA methylase; Region: N6_N4_Mtase; pfam01555
956483001988	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
956483001989	potential frameshift: common BLAST hit: gi|313678679|ref|YP_004056419.1| ISMbov7, transposase
956483001990	potential frameshift: common BLAST hit: gi|313678679|ref|YP_004056419.1| ISMbov7, transposase
956483001991	Integrase core domain; Region: rve; pfam00665
956483001992	Integrase core domain; Region: rve_3; cl15866
956483001993	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
956483001994	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
956483001995	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
956483001996	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
956483001997	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483001998	ABC-type thiamine transport system, ATPase component [Coenzyme metabolism]; Region: ThiQ; COG3840
956483001999	Walker A/P-loop; other site
956483002000	ATP binding site [chemical binding]; other site
956483002001	Q-loop/lid; other site
956483002002	ABC transporter signature motif; other site
956483002003	Walker B; other site
956483002004	D-loop; other site
956483002005	H-loop/switch region; other site
956483002006	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
956483002007	active site
956483002008	hypothetical protein; Validated; Region: PRK00110
956483002009	NAD synthetase; Provisional; Region: PRK13980
956483002010	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
956483002011	homodimer interface [polypeptide binding]; other site
956483002012	NAD binding pocket [chemical binding]; other site
956483002013	ATP binding pocket [chemical binding]; other site
956483002014	Mg binding site [ion binding]; other site
956483002015	active-site loop [active]
956483002016	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
956483002017	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
956483002018	TRAM domain; Region: TRAM; pfam01938
956483002019	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
956483002020	S-adenosylmethionine binding site [chemical binding]; other site
956483002021	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483002022	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
956483002023	Walker A motif; other site
956483002024	ATP binding site [chemical binding]; other site
956483002025	Walker B motif; other site
956483002026	arginine finger; other site
956483002027	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
956483002028	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
956483002029	CoA-binding site [chemical binding]; other site
956483002030	ATP-binding [chemical binding]; other site
956483002031	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
956483002032	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
956483002033	DNA methylase; Region: N6_N4_Mtase; pfam01555
956483002034	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
956483002035	asparagine synthetase A; Reviewed; Region: PRK06462
956483002036	AAA domain; Region: AAA_14; pfam13173
956483002037	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
956483002038	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
956483002039	RNA/DNA hybrid binding site [nucleotide binding]; other site
956483002040	active site
956483002041	Cation transport protein; Region: TrkH; cl17365
956483002042	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
956483002043	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
956483002044	RNA binding surface [nucleotide binding]; other site
956483002045	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
956483002046	active site
956483002047	Chromate transporter; Region: Chromate_transp; cl17781
956483002048	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
956483002049	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
956483002050	S-adenosylmethionine binding site [chemical binding]; other site
956483002051	Protein of unknown function (DUF402); Region: DUF402; cl00979
956483002052	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
956483002053	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
956483002054	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
956483002055	Predicted methyltransferases [General function prediction only]; Region: COG0313
956483002056	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
956483002057	putative SAM binding site [chemical binding]; other site
956483002058	putative homodimer interface [polypeptide binding]; other site
956483002059	DNA polymerase III subunit delta'; Validated; Region: PRK07132
956483002060	DNA polymerase III subunit delta'; Validated; Region: PRK08485
956483002061	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
956483002062	thymidylate kinase; Validated; Region: tmk; PRK00698
956483002063	TMP-binding site; other site
956483002064	ATP-binding site [chemical binding]; other site
956483002065	recombination protein RecR; Reviewed; Region: recR; PRK00076
956483002066	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
956483002067	active site
956483002068	metal binding site [ion binding]; metal-binding site
956483002069	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
956483002070	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483002071	Walker A motif; other site
956483002072	ATP binding site [chemical binding]; other site
956483002073	Walker B motif; other site
956483002074	arginine finger; other site
956483002075	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
956483002076	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
956483002077	phosphoglyceromutase; Provisional; Region: PRK05434
956483002078	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
956483002079	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
956483002080	active site
956483002081	motif I; other site
956483002082	motif II; other site
956483002083	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
956483002084	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
956483002085	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
956483002086	phosphatidate cytidylyltransferase; Region: PLN02953
956483002087	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
956483002088	active site
956483002089	translation initiation factor IF-2; Region: IF-2; TIGR00487
956483002090	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
956483002091	G1 box; other site
956483002092	putative GEF interaction site [polypeptide binding]; other site
956483002093	GTP/Mg2+ binding site [chemical binding]; other site
956483002094	Switch I region; other site
956483002095	G2 box; other site
956483002096	G3 box; other site
956483002097	Switch II region; other site
956483002098	G4 box; other site
956483002099	G5 box; other site
956483002100	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
956483002101	Translation-initiation factor 2; Region: IF-2; pfam11987
956483002102	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
956483002103	Protein of unknown function (DUF448); Region: DUF448; pfam04296
956483002104	putative RNA binding cleft [nucleotide binding]; other site
956483002105	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
956483002106	NusA N-terminal domain; Region: NusA_N; pfam08529
956483002107	NusA-like KH domain; Region: KH_5; pfam13184
956483002108	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
956483002109	G-X-X-G motif; other site
956483002110	hypothetical protein; Provisional; Region: PRK14644
956483002111	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
956483002112	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
956483002113	thymidine kinase; Provisional; Region: PRK04296
956483002114	Walker A/P-loop; other site
956483002115	ATP binding site [chemical binding]; other site
956483002116	Q-loop/lid; other site
956483002117	ABC transporter signature motif; other site
956483002118	Walker B; other site
956483002119	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
956483002120	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
956483002121	interface (dimer of trimers) [polypeptide binding]; other site
956483002122	Substrate-binding/catalytic site; other site
956483002123	Zn-binding sites [ion binding]; other site
956483002124	potential frameshift: common BLAST hit: gi|313678806|ref|YP_004056546.1| ISMbov1, transposase
956483002125	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
956483002126	Integrase core domain; Region: rve; pfam00665
956483002127	hypothetical protein; Provisional; Region: PRK09609
956483002128	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
956483002129	active site
956483002130	catalytic residues [active]
956483002131	Int/Topo IB signature motif; other site
956483002132	DNA binding site [nucleotide binding]
956483002133	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
956483002134	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
956483002135	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
956483002136	mycoides cluster lipoprotein, LppA/P72 family; Region: Mycoplas_LppA; TIGR03490
956483002137	Domain of unknown function(DUF2779); Region: DUF2779; pfam11074
956483002138	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
956483002139	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
956483002140	GatB domain; Region: GatB_Yqey; smart00845
956483002141	amidase; Provisional; Region: PRK07139
956483002142	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
956483002143	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
956483002144	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
956483002145	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
956483002146	RNA binding surface [nucleotide binding]; other site
956483002147	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
956483002148	active site
956483002149	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
956483002150	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
956483002151	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
956483002152	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
956483002153	putative acyl-acceptor binding pocket; other site
956483002154	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
956483002155	GTP-binding protein Der; Reviewed; Region: PRK00093
956483002156	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
956483002157	G1 box; other site
956483002158	GTP/Mg2+ binding site [chemical binding]; other site
956483002159	Switch I region; other site
956483002160	G2 box; other site
956483002161	Switch II region; other site
956483002162	G3 box; other site
956483002163	G4 box; other site
956483002164	G5 box; other site
956483002165	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
956483002166	G1 box; other site
956483002167	GTP/Mg2+ binding site [chemical binding]; other site
956483002168	Switch I region; other site
956483002169	G2 box; other site
956483002170	G3 box; other site
956483002171	Switch II region; other site
956483002172	G4 box; other site
956483002173	G5 box; other site
956483002174	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
956483002175	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
956483002176	CMP-binding site; other site
956483002177	The sites determining sugar specificity; other site
956483002178	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
956483002179	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
956483002180	HSP70 interaction site [polypeptide binding]; other site
956483002181	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
956483002182	Zn binding sites [ion binding]; other site
956483002183	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
956483002184	dimer interface [polypeptide binding]; other site
956483002185	Ribosome-binding factor A; Region: RBFA; pfam02033
956483002186	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
956483002187	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
956483002188	active site
956483002189	HIGH motif; other site
956483002190	dimer interface [polypeptide binding]; other site
956483002191	KMSKS motif; other site
956483002192	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
956483002193	putative tRNA-binding site [nucleotide binding]; other site
956483002194	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DegV; COG1307
956483002195	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
956483002196	acyl carrier protein; Provisional; Region: acpP; PRK00982
956483002197	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
956483002198	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
956483002199	S-adenosylmethionine binding site [chemical binding]; other site
956483002200	peptide chain release factor 1; Validated; Region: prfA; PRK00591
956483002201	This domain is found in peptide chain release factors; Region: PCRF; smart00937
956483002202	RF-1 domain; Region: RF-1; pfam00472
956483002203	Fic/DOC family; Region: Fic; cl00960
956483002204	Uncharacterized conserved protein [Function unknown]; Region: COG1284
956483002205	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
956483002206	potential frameshift: common BLAST hit: gi|313678171|ref|YP_004055911.1| ISMbov1, transposase
956483002207	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
956483002208	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
956483002209	ATP binding site [chemical binding]; other site
956483002210	Mg2+ binding site [ion binding]; other site
956483002211	G-X-G motif; other site
956483002212	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
956483002213	anchoring element; other site
956483002214	dimer interface [polypeptide binding]; other site
956483002215	ATP binding site [chemical binding]; other site
956483002216	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
956483002217	active site
956483002218	putative metal-binding site [ion binding]; other site
956483002219	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
956483002220	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
956483002221	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
956483002222	catalytic residues [active]
956483002223	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
956483002224	SmpB-tmRNA interface; other site
956483002225	HTH-like domain; Region: HTH_21; pfam13276
956483002226	Integrase core domain; Region: rve; pfam00665
956483002227	Transposase [DNA replication, recombination, and repair]; Region: COG5421
956483002228	Archaeal putative transposase ISC1217; Region: DDE_Tnp_2; pfam04693
956483002229	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
956483002230	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
956483002231	Transcriptional regulators [Transcription]; Region: PurR; COG1609
956483002232	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
956483002233	DNA binding site [nucleotide binding]
956483002234	domain linker motif; other site
956483002235	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
956483002236	HTH-like domain; Region: HTH_21; pfam13276
956483002237	Integrase core domain; Region: rve; pfam00665
956483002238	Integrase core domain; Region: rve_3; cl15866
956483002239	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
956483002240	magnesium-transporting ATPase; Provisional; Region: PRK15122
956483002241	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
956483002242	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
956483002243	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
956483002244	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
956483002245	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
956483002246	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
956483002247	Walker A/P-loop; other site
956483002248	ATP binding site [chemical binding]; other site
956483002249	Q-loop/lid; other site
956483002250	ABC transporter signature motif; other site
956483002251	Walker B; other site
956483002252	D-loop; other site
956483002253	H-loop/switch region; other site
956483002254	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
956483002255	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
956483002256	Walker A motif; other site
956483002257	ATP binding site [chemical binding]; other site
956483002258	Walker B motif; other site
956483002259	arginine finger; other site
956483002260	Peptidase family M41; Region: Peptidase_M41; pfam01434
956483002261	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
956483002262	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
956483002263	Ligand Binding Site [chemical binding]; other site
956483002264	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
956483002265	putative active site [active]
956483002266	catalytic residue [active]
956483002267	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
956483002268	AAA domain; Region: AAA_30; pfam13604
956483002269	Family description; Region: UvrD_C_2; pfam13538