-- dump date   	20140619_160030
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
637387000001	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
637387000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387000003	Walker A motif; other site
637387000004	ATP binding site [chemical binding]; other site
637387000005	Walker B motif; other site
637387000006	arginine finger; other site
637387000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
637387000008	DnaA box-binding interface [nucleotide binding]; other site
637387000009	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
637387000010	DNA polymerase III subunit beta; Provisional; Region: PRK14946
637387000011	putative DNA binding surface [nucleotide binding]; other site
637387000012	dimer interface [polypeptide binding]; other site
637387000013	beta-clamp/clamp loader binding surface; other site
637387000014	beta-clamp/translesion DNA polymerase binding surface; other site
637387000015	S4 domain; Region: S4_2; pfam13275
637387000016	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
637387000017	catalytic motif [active]
637387000018	Zn binding site [ion binding]; other site
637387000019	EDD domain protein, DegV family; Region: DegV; TIGR00762
637387000020	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
637387000021	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
637387000022	putative tRNA-binding site [nucleotide binding]; other site
637387000023	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
637387000024	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
637387000025	active site
637387000026	HIGH motif; other site
637387000027	dimer interface [polypeptide binding]; other site
637387000028	KMSKS motif; other site
637387000029	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
637387000030	amphipathic channel; other site
637387000031	Asn-Pro-Ala signature motifs; other site
637387000032	NAD synthetase; Provisional; Region: PRK13980
637387000033	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
637387000034	homodimer interface [polypeptide binding]; other site
637387000035	NAD binding pocket [chemical binding]; other site
637387000036	ATP binding pocket [chemical binding]; other site
637387000037	Mg binding site [ion binding]; other site
637387000038	active-site loop [active]
637387000039	hypothetical protein; Validated; Region: PRK00110
637387000040	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
637387000041	putative phosphoketolase; Provisional; Region: PRK05261
637387000042	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
637387000043	TPP-binding site; other site
637387000044	XFP C-terminal domain; Region: XFP_C; pfam09363
637387000045	Methyltransferase domain; Region: Methyltransf_26; pfam13659
637387000046	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
637387000047	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
637387000048	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
637387000049	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
637387000050	ATP binding site [chemical binding]; other site
637387000051	putative Mg++ binding site [ion binding]; other site
637387000052	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
637387000053	DNA methylase; Region: N6_N4_Mtase; cl17433
637387000054	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
637387000055	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
637387000056	dimer interface [polypeptide binding]; other site
637387000057	putative anticodon binding site; other site
637387000058	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
637387000059	motif 1; other site
637387000060	active site
637387000061	motif 2; other site
637387000062	motif 3; other site
637387000063	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
637387000064	active site
637387000065	substrate binding pocket [chemical binding]; other site
637387000066	homodimer interaction site [polypeptide binding]; other site
637387000067	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
637387000068	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
637387000069	active site
637387000070	P-loop; other site
637387000071	phosphorylation site [posttranslational modification]
637387000072	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
637387000073	active site
637387000074	phosphorylation site [posttranslational modification]
637387000075	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
637387000076	active site
637387000077	dimer interface [polypeptide binding]; other site
637387000078	magnesium binding site [ion binding]; other site
637387000079	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
637387000080	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
637387000081	AP (apurinic/apyrimidinic) site pocket; other site
637387000082	DNA interaction; other site
637387000083	Metal-binding active site; metal-binding site
637387000084	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
637387000085	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
637387000086	intersubunit interface [polypeptide binding]; other site
637387000087	active site
637387000088	Zn2+ binding site [ion binding]; other site
637387000089	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
637387000090	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
637387000091	active site
637387000092	motif I; other site
637387000093	motif II; other site
637387000094	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
637387000095	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
637387000096	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
637387000097	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
637387000098	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
637387000099	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
637387000100	active site turn [active]
637387000101	phosphorylation site [posttranslational modification]
637387000102	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
637387000103	HPr interaction site; other site
637387000104	glycerol kinase (GK) interaction site [polypeptide binding]; other site
637387000105	active site
637387000106	phosphorylation site [posttranslational modification]
637387000107	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
637387000108	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
637387000109	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
637387000110	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
637387000111	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
637387000112	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
637387000113	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
637387000114	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
637387000115	active site
637387000116	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
637387000117	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
637387000118	NAD binding site [chemical binding]; other site
637387000119	homodimer interface [polypeptide binding]; other site
637387000120	active site
637387000121	substrate binding site [chemical binding]; other site
637387000122	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
637387000123	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
637387000124	DXD motif; other site
637387000125	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cl00425
637387000126	phosphate binding site [ion binding]; other site
637387000127	dimer interface [polypeptide binding]; other site
637387000128	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
637387000129	active site
637387000130	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
637387000131	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000132	Walker A/P-loop; other site
637387000133	ATP binding site [chemical binding]; other site
637387000134	Q-loop/lid; other site
637387000135	ABC transporter signature motif; other site
637387000136	Walker B; other site
637387000137	D-loop; other site
637387000138	H-loop/switch region; other site
637387000139	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
637387000140	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
637387000141	P loop; other site
637387000142	GTP binding site [chemical binding]; other site
637387000143	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
637387000144	DNA binding residues [nucleotide binding]
637387000145	AAA domain; Region: AAA_14; pfam13173
637387000146	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387000147	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
637387000148	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
637387000149	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
637387000150	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
637387000151	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
637387000152	putative active site [active]
637387000153	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
637387000154	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
637387000155	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
637387000156	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
637387000157	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
637387000158	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
637387000159	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
637387000160	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
637387000161	DHH family; Region: DHH; pfam01368
637387000162	DHHA1 domain; Region: DHHA1; pfam02272
637387000163	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
637387000164	DHH family; Region: DHH; pfam01368
637387000165	DHHA1 domain; Region: DHHA1; pfam02272
637387000166	hypothetical protein; Provisional; Region: PRK14644
637387000167	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
637387000168	Sm and related proteins; Region: Sm_like; cl00259
637387000169	heptamer interface [polypeptide binding]; other site
637387000170	Sm1 motif; other site
637387000171	hexamer interface [polypeptide binding]; other site
637387000172	RNA binding site [nucleotide binding]; other site
637387000173	Sm2 motif; other site
637387000174	transcription termination factor NusA; Region: NusA; TIGR01953
637387000175	NusA-like KH domain; Region: KH_5; pfam13184
637387000176	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
637387000177	G-X-X-G motif; other site
637387000178	translation initiation factor IF-2; Region: IF-2; TIGR00487
637387000179	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
637387000180	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
637387000181	G1 box; other site
637387000182	putative GEF interaction site [polypeptide binding]; other site
637387000183	GTP/Mg2+ binding site [chemical binding]; other site
637387000184	Switch I region; other site
637387000185	G2 box; other site
637387000186	G3 box; other site
637387000187	Switch II region; other site
637387000188	G4 box; other site
637387000189	G5 box; other site
637387000190	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
637387000191	Translation-initiation factor 2; Region: IF-2; pfam11987
637387000192	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
637387000193	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
637387000194	active site
637387000195	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387000196	Walker A motif; other site
637387000197	ATP binding site [chemical binding]; other site
637387000198	Walker B motif; other site
637387000199	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
637387000200	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
637387000201	CoA-binding site [chemical binding]; other site
637387000202	ATP-binding [chemical binding]; other site
637387000203	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
637387000204	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
637387000205	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
637387000206	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
637387000207	putative active site [active]
637387000208	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
637387000209	Walker A/P-loop; other site
637387000210	ATP binding site [chemical binding]; other site
637387000211	Q-loop/lid; other site
637387000212	ABC transporter signature motif; other site
637387000213	Walker B; other site
637387000214	D-loop; other site
637387000215	H-loop/switch region; other site
637387000216	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
637387000217	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
637387000218	active site
637387000219	catalytic motif [active]
637387000220	Zn binding site [ion binding]; other site
637387000221	GTPase Era; Reviewed; Region: era; PRK00089
637387000222	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
637387000223	G1 box; other site
637387000224	GTP/Mg2+ binding site [chemical binding]; other site
637387000225	Switch I region; other site
637387000226	G2 box; other site
637387000227	Switch II region; other site
637387000228	G3 box; other site
637387000229	G4 box; other site
637387000230	G5 box; other site
637387000231	KH domain; Region: KH_2; pfam07650
637387000232	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
637387000233	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
637387000234	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
637387000235	active site
637387000236	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
637387000237	TRAM domain; Region: TRAM; cl01282
637387000238	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
637387000239	S-adenosylmethionine binding site [chemical binding]; other site
637387000240	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
637387000241	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
637387000242	S-adenosylmethionine binding site [chemical binding]; other site
637387000243	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
637387000244	active site
637387000245	catalytic residues [active]
637387000246	metal binding site [ion binding]; metal-binding site
637387000247	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit [DNA replication, recombination, and repair]; Region: GyrB; COG0187
637387000248	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
637387000249	Mg2+ binding site [ion binding]; other site
637387000250	G-X-G motif; other site
637387000251	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
637387000252	anchoring element; other site
637387000253	dimer interface [polypeptide binding]; other site
637387000254	ATP binding site [chemical binding]; other site
637387000255	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
637387000256	active site
637387000257	putative metal-binding site [ion binding]; other site
637387000258	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
637387000259	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
637387000260	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
637387000261	CAP-like domain; other site
637387000262	active site
637387000263	primary dimer interface [polypeptide binding]; other site
637387000264	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
637387000265	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
637387000266	active site
637387000267	metal binding site [ion binding]; metal-binding site
637387000268	homotetramer interface [polypeptide binding]; other site
637387000269	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
637387000270	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
637387000271	active site
637387000272	motif I; other site
637387000273	motif II; other site
637387000274	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
637387000275	Ribonuclease HIII [DNA replication, recombination, and repair]; Region: RnhC; COG1039
637387000276	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
637387000277	RNA/DNA hybrid binding site [nucleotide binding]; other site
637387000278	active site
637387000279	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
637387000280	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
637387000281	nucleotide binding site [chemical binding]; other site
637387000282	recombination factor protein RarA; Reviewed; Region: PRK13342
637387000283	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387000284	Walker A motif; other site
637387000285	ATP binding site [chemical binding]; other site
637387000286	Walker B motif; other site
637387000287	arginine finger; other site
637387000288	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
637387000289	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
637387000290	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
637387000291	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
637387000292	dimer interface [polypeptide binding]; other site
637387000293	motif 1; other site
637387000294	active site
637387000295	motif 2; other site
637387000296	motif 3; other site
637387000297	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
637387000298	ligand binding site [chemical binding]; other site
637387000299	active site
637387000300	UGI interface [polypeptide binding]; other site
637387000301	catalytic site [active]
637387000302	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
637387000303	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
637387000304	putative tRNA-binding site [nucleotide binding]; other site
637387000305	B3/4 domain; Region: B3_4; pfam03483
637387000306	tRNA synthetase B5 domain; Region: B5; pfam03484
637387000307	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
637387000308	motif 1; other site
637387000309	dimer interface [polypeptide binding]; other site
637387000310	active site
637387000311	motif 2; other site
637387000312	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
637387000313	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
637387000314	dimer interface [polypeptide binding]; other site
637387000315	active site
637387000316	glycine-pyridoxal phosphate binding site [chemical binding]; other site
637387000317	folate binding site [chemical binding]; other site
637387000318	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
637387000319	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
637387000320	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
637387000321	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
637387000322	HSP70 interaction site [polypeptide binding]; other site
637387000323	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
637387000324	Zn binding sites [ion binding]; other site
637387000325	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
637387000326	dimer interface [polypeptide binding]; other site
637387000327	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
637387000328	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
637387000329	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
637387000330	putative acyl-acceptor binding pocket; other site
637387000331	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
637387000332	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
637387000333	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
637387000334	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
637387000335	RNA binding surface [nucleotide binding]; other site
637387000336	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
637387000337	active site
637387000338	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
637387000339	amidase; Provisional; Region: PRK07139
637387000340	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
637387000341	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
637387000342	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
637387000343	DpnII restriction endonuclease; Region: DpnII; pfam04556
637387000344	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
637387000345	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
637387000346	non-specific DNA binding site [nucleotide binding]; other site
637387000347	salt bridge; other site
637387000348	sequence-specific DNA binding site [nucleotide binding]; other site
637387000349	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
637387000350	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
637387000351	Divergent AAA domain; Region: AAA_4; pfam04326
637387000352	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
637387000353	Helix-turn-helix domain; Region: HTH_36; pfam13730
637387000354	oligoendopeptidase F; Region: pepF; TIGR00181
637387000355	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
637387000356	active site
637387000357	Zn binding site [ion binding]; other site
637387000358	trigger factor; Region: tig; TIGR00115
637387000359	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
637387000360	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
637387000361	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
637387000362	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
637387000363	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
637387000364	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
637387000365	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
637387000366	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
637387000367	GTP/Mg2+ binding site [chemical binding]; other site
637387000368	G4 box; other site
637387000369	G5 box; other site
637387000370	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
637387000371	G1 box; other site
637387000372	G1 box; other site
637387000373	GTP/Mg2+ binding site [chemical binding]; other site
637387000374	Switch I region; other site
637387000375	G2 box; other site
637387000376	G2 box; other site
637387000377	G3 box; other site
637387000378	G3 box; other site
637387000379	Switch II region; other site
637387000380	Switch II region; other site
637387000381	G4 box; other site
637387000382	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
637387000383	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000384	Walker A/P-loop; other site
637387000385	ATP binding site [chemical binding]; other site
637387000386	Q-loop/lid; other site
637387000387	ABC transporter signature motif; other site
637387000388	Walker B; other site
637387000389	D-loop; other site
637387000390	H-loop/switch region; other site
637387000391	ABC-2 type transporter; Region: ABC2_membrane; cl17235
637387000392	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
637387000393	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
637387000394	dimer interface [polypeptide binding]; other site
637387000395	catalytic triad [active]
637387000396	peroxidatic and resolving cysteines [active]
637387000397	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
637387000398	GTP-binding protein Der; Reviewed; Region: PRK00093
637387000399	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
637387000400	G1 box; other site
637387000401	GTP/Mg2+ binding site [chemical binding]; other site
637387000402	Switch I region; other site
637387000403	G2 box; other site
637387000404	Switch II region; other site
637387000405	G3 box; other site
637387000406	G4 box; other site
637387000407	G5 box; other site
637387000408	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
637387000409	G1 box; other site
637387000410	GTP/Mg2+ binding site [chemical binding]; other site
637387000411	Switch I region; other site
637387000412	G2 box; other site
637387000413	G3 box; other site
637387000414	Switch II region; other site
637387000415	G4 box; other site
637387000416	G5 box; other site
637387000417	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
637387000418	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
637387000419	CMP-binding site; other site
637387000420	The sites determining sugar specificity; other site
637387000421	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
637387000422	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
637387000423	RNA binding surface [nucleotide binding]; other site
637387000424	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
637387000425	active site
637387000426	putative nicotinate-nucleotide adenylyltransferase; Validated; Region: nadD; PRK07152
637387000427	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
637387000428	active site
637387000429	(T/H)XGH motif; other site
637387000430	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
637387000431	Zn2+ binding site [ion binding]; other site
637387000432	Mg2+ binding site [ion binding]; other site
637387000433	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
637387000434	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
637387000435	active site
637387000436	DNA binding site [nucleotide binding]
637387000437	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
637387000438	trimerization site [polypeptide binding]; other site
637387000439	active site
637387000440	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
637387000441	Aminotransferase class-V; Region: Aminotran_5; pfam00266
637387000442	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
637387000443	catalytic residue [active]
637387000444	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
637387000445	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
637387000446	LicD family; Region: LicD; pfam04991
637387000447	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
637387000448	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
637387000449	NAD binding site [chemical binding]; other site
637387000450	Membrane transport protein; Region: Mem_trans; cl09117
637387000451	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
637387000452	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
637387000453	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
637387000454	active site
637387000455	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
637387000456	Phosphotransferase enzyme family; Region: APH; pfam01636
637387000457	active site
637387000458	substrate binding site [chemical binding]; other site
637387000459	ATP binding site [chemical binding]; other site
637387000460	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
637387000461	23S rRNA interface [nucleotide binding]; other site
637387000462	L3 interface [polypeptide binding]; other site
637387000463	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
637387000464	LicD family; Region: LicD; pfam04991
637387000465	hypothetical protein; Provisional; Region: PRK09609
637387000466	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; cl01319
637387000467	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
637387000468	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
637387000469	intersubunit interface [polypeptide binding]; other site
637387000470	active site
637387000471	zinc binding site [ion binding]; other site
637387000472	Na+ binding site [ion binding]; other site
637387000473	Staphylococcal nuclease homologues; Region: SNc; smart00318
637387000474	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
637387000475	Catalytic site; other site
637387000476	pyruvate kinase; Provisional; Region: PRK05826
637387000477	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
637387000478	domain interfaces; other site
637387000479	active site
637387000480	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
637387000481	G1 box; other site
637387000482	GTP/Mg2+ binding site [chemical binding]; other site
637387000483	Switch I region; other site
637387000484	G2 box; other site
637387000485	G3 box; other site
637387000486	Switch II region; other site
637387000487	G4 box; other site
637387000488	G5 box; other site
637387000489	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK13964
637387000490	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387000491	active site
637387000492	nucleotide binding site [chemical binding]; other site
637387000493	HIGH motif; other site
637387000494	KMSKS motif; other site
637387000495	Acetokinase family; Region: Acetate_kinase; cl17229
637387000496	propionate/acetate kinase; Provisional; Region: PRK12379
637387000497	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
637387000498	RNA polymerase sigma factor SigD; Validated; Region: PRK07670
637387000499	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
637387000500	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
637387000501	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
637387000502	homodimer interface [polypeptide binding]; other site
637387000503	NADP binding site [chemical binding]; other site
637387000504	substrate binding site [chemical binding]; other site
637387000505	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
637387000506	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387000507	active site
637387000508	HIGH motif; other site
637387000509	nucleotide binding site [chemical binding]; other site
637387000510	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
637387000511	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
637387000512	active site
637387000513	KMSKS motif; other site
637387000514	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
637387000515	tRNA binding surface [nucleotide binding]; other site
637387000516	anticodon binding site; other site
637387000517	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
637387000518	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
637387000519	OB-fold nucleic acid binding domain; Region: tRNA_anti_2; pfam13742
637387000520	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
637387000521	generic binding surface I; other site
637387000522	Exonuclease VII small subunit; Region: Exonuc_VII_S; cl00750
637387000523	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
637387000524	Part of AAA domain; Region: AAA_19; pfam13245
637387000525	AAA domain; Region: AAA_12; pfam13087
637387000526	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
637387000527	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
637387000528	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
637387000529	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
637387000530	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387000531	dimer interface [polypeptide binding]; other site
637387000532	conserved gate region; other site
637387000533	putative PBP binding loops; other site
637387000534	ABC-ATPase subunit interface; other site
637387000535	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
637387000536	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387000537	dimer interface [polypeptide binding]; other site
637387000538	conserved gate region; other site
637387000539	putative PBP binding loops; other site
637387000540	ABC-ATPase subunit interface; other site
637387000541	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
637387000542	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
637387000543	Walker A/P-loop; other site
637387000544	ATP binding site [chemical binding]; other site
637387000545	Q-loop/lid; other site
637387000546	ABC transporter signature motif; other site
637387000547	Walker B; other site
637387000548	D-loop; other site
637387000549	H-loop/switch region; other site
637387000550	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
637387000551	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000552	AAA domain; Region: AAA_21; pfam13304
637387000553	Walker A/P-loop; other site
637387000554	ATP binding site [chemical binding]; other site
637387000555	Q-loop/lid; other site
637387000556	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
637387000557	ABC transporter signature motif; other site
637387000558	Walker B; other site
637387000559	D-loop; other site
637387000560	H-loop/switch region; other site
637387000561	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
637387000562	asparagine synthetase AsnA; Provisional; Region: PRK05425
637387000563	motif 1; other site
637387000564	dimer interface [polypeptide binding]; other site
637387000565	active site
637387000566	motif 2; other site
637387000567	motif 3; other site
637387000568	Uncharacterized conserved protein [Function unknown]; Region: COG4095
637387000569	PQ loop repeat; Region: PQ-loop; pfam04193
637387000570	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
637387000571	putative active site pocket [active]
637387000572	dimerization interface [polypeptide binding]; other site
637387000573	putative catalytic residue [active]
637387000574	Fic family protein [Function unknown]; Region: COG3177
637387000575	Fic/DOC family; Region: Fic; pfam02661
637387000576	B3/4 domain; Region: B3_4; pfam03483
637387000577	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
637387000578	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
637387000579	enolase; Provisional; Region: eno; PRK00077
637387000580	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
637387000581	dimer interface [polypeptide binding]; other site
637387000582	metal binding site [ion binding]; metal-binding site
637387000583	substrate binding pocket [chemical binding]; other site
637387000584	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
637387000585	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
637387000586	active site
637387000587	metal binding site [ion binding]; metal-binding site
637387000588	substrate binding site [chemical binding]; other site
637387000589	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
637387000590	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
637387000591	elongation factor Tu; Reviewed; Region: PRK00049
637387000592	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
637387000593	G1 box; other site
637387000594	GEF interaction site [polypeptide binding]; other site
637387000595	GTP/Mg2+ binding site [chemical binding]; other site
637387000596	Switch I region; other site
637387000597	G2 box; other site
637387000598	G3 box; other site
637387000599	Switch II region; other site
637387000600	G4 box; other site
637387000601	G5 box; other site
637387000602	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
637387000603	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
637387000604	Antibiotic Binding Site [chemical binding]; other site
637387000605	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
637387000606	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
637387000607	UGMP family protein; Validated; Region: PRK09604
637387000608	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
637387000609	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; cl01839
637387000610	Predicted acetyltransferase [General function prediction only]; Region: COG3393
637387000611	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
637387000612	signal recognition particle protein; Provisional; Region: PRK10867
637387000613	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
637387000614	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
637387000615	P loop; other site
637387000616	GTP binding site [chemical binding]; other site
637387000617	Signal peptide binding domain; Region: SRP_SPB; pfam02978
637387000618	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; pfam09529
637387000619	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
637387000620	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
637387000621	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
637387000622	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
637387000623	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
637387000624	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
637387000625	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
637387000626	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
637387000627	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
637387000628	beta subunit interaction interface [polypeptide binding]; other site
637387000629	Walker A motif; other site
637387000630	ATP binding site [chemical binding]; other site
637387000631	Walker B motif; other site
637387000632	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
637387000633	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
637387000634	core domain interface [polypeptide binding]; other site
637387000635	delta subunit interface [polypeptide binding]; other site
637387000636	epsilon subunit interface [polypeptide binding]; other site
637387000637	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
637387000638	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
637387000639	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
637387000640	alpha subunit interaction interface [polypeptide binding]; other site
637387000641	Walker A motif; other site
637387000642	ATP binding site [chemical binding]; other site
637387000643	Walker B motif; other site
637387000644	inhibitor binding site; inhibition site
637387000645	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
637387000646	F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) [Energy production and conversion]; Region: AtpC; COG0355
637387000647	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
637387000648	gamma subunit interface [polypeptide binding]; other site
637387000649	epsilon subunit interface [polypeptide binding]; other site
637387000650	LBP interface [polypeptide binding]; other site
637387000651	Smr domain; Region: Smr; pfam01713
637387000652	putative transposase OrfB; Reviewed; Region: PHA02517
637387000653	HTH-like domain; Region: HTH_21; pfam13276
637387000654	Integrase core domain; Region: rve; pfam00665
637387000655	Integrase core domain; Region: rve_2; pfam13333
637387000656	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
637387000657	active site turn [active]
637387000658	phosphorylation site [posttranslational modification]
637387000659	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
637387000660	HPr interaction site; other site
637387000661	glycerol kinase (GK) interaction site [polypeptide binding]; other site
637387000662	active site
637387000663	phosphorylation site [posttranslational modification]
637387000664	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
637387000665	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
637387000666	putative ligand binding site [chemical binding]; other site
637387000667	putative NAD binding site [chemical binding]; other site
637387000668	catalytic site [active]
637387000669	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
637387000670	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387000671	dimer interface [polypeptide binding]; other site
637387000672	conserved gate region; other site
637387000673	ABC-ATPase subunit interface; other site
637387000674	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
637387000675	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
637387000676	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387000677	dimer interface [polypeptide binding]; other site
637387000678	conserved gate region; other site
637387000679	putative PBP binding loops; other site
637387000680	ABC-ATPase subunit interface; other site
637387000681	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
637387000682	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
637387000683	Walker A/P-loop; other site
637387000684	ATP binding site [chemical binding]; other site
637387000685	Q-loop/lid; other site
637387000686	ABC transporter signature motif; other site
637387000687	Walker B; other site
637387000688	D-loop; other site
637387000689	H-loop/switch region; other site
637387000690	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
637387000691	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
637387000692	Walker A/P-loop; other site
637387000693	ATP binding site [chemical binding]; other site
637387000694	Q-loop/lid; other site
637387000695	AAA domain; Region: AAA_21; pfam13304
637387000696	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
637387000697	ABC transporter signature motif; other site
637387000698	Walker B; other site
637387000699	D-loop; other site
637387000700	H-loop/switch region; other site
637387000701	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
637387000702	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
637387000703	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
637387000704	interface (dimer of trimers) [polypeptide binding]; other site
637387000705	Substrate-binding/catalytic site; other site
637387000706	Zn-binding sites [ion binding]; other site
637387000707	AAA domain; Region: AAA_14; pfam13173
637387000708	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387000709	AAA domain; Region: AAA_14; pfam13173
637387000710	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387000711	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387000712	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
637387000713	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387000714	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
637387000715	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
637387000716	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
637387000717	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
637387000718	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
637387000719	phosphoglyceromutase; Provisional; Region: PRK05434
637387000720	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
637387000721	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
637387000722	active site
637387000723	motif I; other site
637387000724	motif II; other site
637387000725	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
637387000726	Topoisomerase II-associated protein PAT1; Region: PAT1; pfam09770
637387000727	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
637387000728	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
637387000729	nucleotide binding region [chemical binding]; other site
637387000730	helicase superfamily c-terminal domain; Region: HELICc; smart00490
637387000731	ATP-binding site [chemical binding]; other site
637387000732	Uncharacterized conserved protein [Function unknown]; Region: COG1284
637387000733	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
637387000734	Uncharacterized conserved protein [Function unknown]; Region: COG1284
637387000735	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
637387000736	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
637387000737	Endonuclease I; Region: Endonuclease_1; cl01003
637387000738	excinuclease ABC subunit B; Provisional; Region: PRK05298
637387000739	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
637387000740	ATP binding site [chemical binding]; other site
637387000741	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
637387000742	nucleotide binding region [chemical binding]; other site
637387000743	ATP-binding site [chemical binding]; other site
637387000744	Ultra-violet resistance protein B; Region: UvrB; pfam12344
637387000745	UvrB/uvrC motif; Region: UVR; pfam02151
637387000746	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
637387000747	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
637387000748	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
637387000749	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
637387000750	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
637387000751	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
637387000752	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
637387000753	RPB1 interaction site [polypeptide binding]; other site
637387000754	RPB10 interaction site [polypeptide binding]; other site
637387000755	RPB11 interaction site [polypeptide binding]; other site
637387000756	RPB3 interaction site [polypeptide binding]; other site
637387000757	RPB12 interaction site [polypeptide binding]; other site
637387000758	DNA-directed RNA polymerase subunit gamma; Provisional; Region: rpoC1; PRK02625
637387000759	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
637387000760	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
637387000761	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
637387000762	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
637387000763	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
637387000764	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
637387000765	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
637387000766	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
637387000767	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
637387000768	DNA binding site [nucleotide binding]
637387000769	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
637387000770	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
637387000771	active site
637387000772	catalytic triad [active]
637387000773	oxyanion hole [active]
637387000774	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
637387000775	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
637387000776	oligomer interface [polypeptide binding]; other site
637387000777	active site
637387000778	metal binding site [ion binding]; metal-binding site
637387000779	hypothetical protein; Provisional; Region: PRK00523
637387000780	DNA topoisomerase I; Validated; Region: PRK05582
637387000781	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
637387000782	active site
637387000783	metal binding site [ion binding]; metal-binding site
637387000784	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
637387000785	domain I; other site
637387000786	DNA binding groove [nucleotide binding]
637387000787	phosphate binding site [ion binding]; other site
637387000788	domain II; other site
637387000789	domain III; other site
637387000790	nucleotide binding site [chemical binding]; other site
637387000791	catalytic site [active]
637387000792	domain IV; other site
637387000793	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
637387000794	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
637387000795	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
637387000796	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
637387000797	dimer interface [polypeptide binding]; other site
637387000798	ssDNA binding site [nucleotide binding]; other site
637387000799	tetramer (dimer of dimers) interface [polypeptide binding]; other site
637387000800	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
637387000801	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
637387000802	trigger factor; Region: tig; TIGR00115
637387000803	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
637387000804	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000805	Walker A/P-loop; other site
637387000806	ATP binding site [chemical binding]; other site
637387000807	Q-loop/lid; other site
637387000808	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
637387000809	ABC transporter; Region: ABC_tran_2; pfam12848
637387000810	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000811	Walker A/P-loop; other site
637387000812	ATP binding site [chemical binding]; other site
637387000813	Q-loop/lid; other site
637387000814	ABC transporter signature motif; other site
637387000815	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
637387000816	Walker B; other site
637387000817	D-loop; other site
637387000818	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
637387000819	RuvA N terminal domain; Region: RuvA_N; pfam01330
637387000820	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
637387000821	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387000822	Walker A motif; other site
637387000823	ATP binding site [chemical binding]; other site
637387000824	DNA protecting protein DprA; Region: dprA; TIGR00732
637387000825	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
637387000826	RuvA N terminal domain; Region: RuvA_N; pfam01330
637387000827	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
637387000828	Holliday junction DNA helicase, RuvB subunit; Region: ruvB; TIGR00635
637387000829	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
637387000830	DNA methylase; Region: N6_N4_Mtase; cl17433
637387000831	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
637387000832	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
637387000833	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
637387000834	AAA-like domain; Region: AAA_10; pfam12846
637387000835	Zonular occludens toxin (Zot); Region: Zot; cl17485
637387000836	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
637387000837	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
637387000838	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
637387000839	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
637387000840	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
637387000841	Protein export membrane protein; Region: SecD_SecF; cl14618
637387000842	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02193
637387000843	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
637387000844	RNA binding site [nucleotide binding]; other site
637387000845	active site
637387000846	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
637387000847	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
637387000848	active site
637387000849	motif I; other site
637387000850	motif II; other site
637387000851	hypothetical protein; Provisional; Region: PRK07143
637387000852	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387000853	active site
637387000854	nucleotide binding site [chemical binding]; other site
637387000855	HIGH motif; other site
637387000856	KMSKS motif; other site
637387000857	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
637387000858	Mycoplasma MG185/MG260 protein; Region: Lipoprotein_X; pfam03305
637387000859	Putative mycoplasma lipoprotein, C-terminal region; Region: Lipoprotein_10; pfam03202
637387000860	Micrococcal nuclease (thermonuclease) homologs [DNA replication, recombination, and repair]; Region: COG1525
637387000861	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140
637387000862	Catalytic site; other site
637387000863	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
637387000864	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000865	Walker A/P-loop; other site
637387000866	ATP binding site [chemical binding]; other site
637387000867	Q-loop/lid; other site
637387000868	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
637387000869	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000870	ABC transporter signature motif; other site
637387000871	Walker B; other site
637387000872	D-loop; other site
637387000873	H-loop/switch region; other site
637387000874	TOBE domain; Region: TOBE_2; pfam08402
637387000875	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387000876	dimer interface [polypeptide binding]; other site
637387000877	conserved gate region; other site
637387000878	putative PBP binding loops; other site
637387000879	ABC-ATPase subunit interface; other site
637387000880	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
637387000881	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387000882	dimer interface [polypeptide binding]; other site
637387000883	conserved gate region; other site
637387000884	putative PBP binding loops; other site
637387000885	ABC-ATPase subunit interface; other site
637387000886	RmuC family; Region: RmuC; pfam02646
637387000887	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
637387000888	Coenzyme A binding pocket [chemical binding]; other site
637387000889	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
637387000890	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
637387000891	conserved cys residue [active]
637387000892	DNA gyrase subunit A; Validated; Region: PRK05560
637387000893	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
637387000894	CAP-like domain; other site
637387000895	active site
637387000896	primary dimer interface [polypeptide binding]; other site
637387000897	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
637387000898	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
637387000899	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
637387000900	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
637387000901	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
637387000902	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
637387000903	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
637387000904	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
637387000905	RNA binding surface [nucleotide binding]; other site
637387000906	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
637387000907	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
637387000908	GrpE; Region: GrpE; pfam01025
637387000909	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
637387000910	dimer interface [polypeptide binding]; other site
637387000911	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
637387000912	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
637387000913	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
637387000914	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
637387000915	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
637387000916	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
637387000917	23S rRNA binding site [nucleotide binding]; other site
637387000918	L21 binding site [polypeptide binding]; other site
637387000919	L13 binding site [polypeptide binding]; other site
637387000920	HTH-like domain; Region: HTH_21; pfam13276
637387000921	Transposase, Mutator family; Region: Transposase_mut; pfam00872
637387000922	MULE transposase domain; Region: MULE; pfam10551
637387000923	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
637387000924	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
637387000925	active site
637387000926	catalytic residues [active]
637387000927	DNA binding site [nucleotide binding]
637387000928	Int/Topo IB signature motif; other site
637387000929	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
637387000930	Part of AAA domain; Region: AAA_19; pfam13245
637387000931	AAA domain; Region: AAA_12; pfam13087
637387000932	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
637387000933	thiamine kinase; Region: ycfN_thiK; TIGR02721
637387000934	active site
637387000935	substrate binding site [chemical binding]; other site
637387000936	ATP binding site [chemical binding]; other site
637387000937	GTP-binding protein LepA; Provisional; Region: PRK05433
637387000938	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
637387000939	G1 box; other site
637387000940	putative GEF interaction site [polypeptide binding]; other site
637387000941	GTP/Mg2+ binding site [chemical binding]; other site
637387000942	Switch I region; other site
637387000943	G2 box; other site
637387000944	G3 box; other site
637387000945	Switch II region; other site
637387000946	G4 box; other site
637387000947	G5 box; other site
637387000948	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
637387000949	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
637387000950	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
637387000951	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
637387000952	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
637387000953	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12903
637387000954	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
637387000955	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387000956	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
637387000957	Walker A/P-loop; other site
637387000958	ATP binding site [chemical binding]; other site
637387000959	Q-loop/lid; other site
637387000960	ABC transporter signature motif; other site
637387000961	Walker B; other site
637387000962	D-loop; other site
637387000963	H-loop/switch region; other site
637387000964	High affinity transport system protein p37; Region: Mycoplasma_p37; pfam06646
637387000965	membrane protein; Provisional; Region: PRK14418
637387000966	preprotein translocase subunit SecA; Reviewed; Region: PRK09200
637387000967	AAA domain; Region: AAA_14; pfam13173
637387000968	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387000969	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
637387000970	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
637387000971	DNA binding site [nucleotide binding]
637387000972	catalytic residue [active]
637387000973	H2TH interface [polypeptide binding]; other site
637387000974	putative catalytic residues [active]
637387000975	turnover-facilitating residue; other site
637387000976	intercalation triad [nucleotide binding]; other site
637387000977	8OG recognition residue [nucleotide binding]; other site
637387000978	putative reading head residues; other site
637387000979	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
637387000980	AAA domain; Region: AAA_14; pfam13173
637387000981	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387000982	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
637387000983	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
637387000984	active site
637387000985	dimer interface [polypeptide binding]; other site
637387000986	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
637387000987	dimer interface [polypeptide binding]; other site
637387000988	active site
637387000989	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
637387000990	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
637387000991	glycyl-tRNA synthetase; Provisional; Region: PRK04173
637387000992	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
637387000993	motif 1; other site
637387000994	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
637387000995	active site
637387000996	motif 2; other site
637387000997	motif 3; other site
637387000998	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
637387000999	anticodon binding site; other site
637387001000	DNA primase, catalytic core; Region: dnaG; TIGR01391
637387001001	CHC2 zinc finger; Region: zf-CHC2; cl17510
637387001002	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
637387001003	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
637387001004	active site
637387001005	metal binding site [ion binding]; metal-binding site
637387001006	interdomain interaction site; other site
637387001007	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
637387001008	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
637387001009	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
637387001010	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
637387001011	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
637387001012	DNA binding residues [nucleotide binding]
637387001013	Uncharacterized conserved protein [Function unknown]; Region: COG0327
637387001014	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
637387001015	dUTPase; Region: dUTPase_2; pfam08761
637387001016	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527
637387001017	active site
637387001018	homodimer interface [polypeptide binding]; other site
637387001019	metal binding site [ion binding]; metal-binding site
637387001020	SdpI/YhfL protein family; Region: SdpI; pfam13630
637387001021	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387001022	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
637387001023	Walker A motif; other site
637387001024	ATP binding site [chemical binding]; other site
637387001025	Walker B motif; other site
637387001026	arginine finger; other site
637387001027	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
637387001028	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
637387001029	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
637387001030	HIGH motif; other site
637387001031	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
637387001032	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387001033	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387001034	active site
637387001035	KMSKS motif; other site
637387001036	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
637387001037	tRNA binding surface [nucleotide binding]; other site
637387001038	anticodon binding site; other site
637387001039	Predicted membrane protein [Function unknown]; Region: COG3601
637387001040	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
637387001041	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
637387001042	active site
637387001043	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
637387001044	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
637387001045	reticulocyte binding/rhoptry protein; Region: 235kDa-fam; TIGR01612
637387001046	NAD-dependent DNA ligase (contains BRCT domain type II) [DNA replication, recombination, and repair]; Region: Lig; COG0272
637387001047	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
637387001048	nucleotide binding pocket [chemical binding]; other site
637387001049	K-X-D-G motif; other site
637387001050	catalytic site [active]
637387001051	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
637387001052	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
637387001053	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
637387001054	Dimer interface [polypeptide binding]; other site
637387001055	BRCT sequence motif; other site
637387001056	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
637387001057	dimer interface [polypeptide binding]; other site
637387001058	substrate binding site [chemical binding]; other site
637387001059	catalytic triad [active]
637387001060	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
637387001061	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
637387001062	active site
637387001063	trimer interface [polypeptide binding]; other site
637387001064	allosteric site; other site
637387001065	active site lid [active]
637387001066	hexamer (dimer of trimers) interface [polypeptide binding]; other site
637387001067	Amidohydrolase; Region: Amidohydro_4; pfam13147
637387001068	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
637387001069	active site
637387001070	Phosphoglycerate kinase; Region: PGK; pfam00162
637387001071	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
637387001072	substrate binding site [chemical binding]; other site
637387001073	hinge regions; other site
637387001074	ADP binding site [chemical binding]; other site
637387001075	catalytic site [active]
637387001076	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
637387001077	active site turn [active]
637387001078	phosphorylation site [posttranslational modification]
637387001079	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
637387001080	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
637387001081	active site
637387001082	HIGH motif; other site
637387001083	dimer interface [polypeptide binding]; other site
637387001084	KMSKS motif; other site
637387001085	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
637387001086	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
637387001087	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
637387001088	active site
637387001089	dimer interface [polypeptide binding]; other site
637387001090	motif 1; other site
637387001091	motif 2; other site
637387001092	motif 3; other site
637387001093	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
637387001094	anticodon binding site; other site
637387001095	Isochorismatase family; Region: Isochorismatase; pfam00857
637387001096	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
637387001097	catalytic triad [active]
637387001098	conserved cis-peptide bond; other site
637387001099	Smr domain; Region: Smr; pfam01713
637387001100	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
637387001101	intersubunit interface [polypeptide binding]; other site
637387001102	active site
637387001103	catalytic residue [active]
637387001104	Thymidine phosphorylase [Nucleotide transport and metabolism]; Region: DeoA; COG0213
637387001105	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
637387001106	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
637387001107	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
637387001108	Purine-nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: DeoD; COG0813
637387001109	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
637387001110	6-phosphofructokinase; Provisional; Region: PRK03202
637387001111	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
637387001112	active site
637387001113	ADP/pyrophosphate binding site [chemical binding]; other site
637387001114	dimerization interface [polypeptide binding]; other site
637387001115	allosteric effector site; other site
637387001116	fructose-1,6-bisphosphate binding site; other site
637387001117	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
637387001118	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
637387001119	active site
637387001120	motif I; other site
637387001121	motif II; other site
637387001122	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
637387001123	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
637387001124	AAA domain; Region: AAA_14; pfam13173
637387001125	GTPase CgtA; Reviewed; Region: obgE; PRK12297
637387001126	GTP1/OBG; Region: GTP1_OBG; pfam01018
637387001127	Obg GTPase; Region: Obg; cd01898
637387001128	G1 box; other site
637387001129	GTP/Mg2+ binding site [chemical binding]; other site
637387001130	Switch I region; other site
637387001131	G2 box; other site
637387001132	G3 box; other site
637387001133	Switch II region; other site
637387001134	G4 box; other site
637387001135	G5 box; other site
637387001136	Obg family GTPase CgtA, C-terminal extension; Region: Obg_CgtA_exten; TIGR03595
637387001137	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
637387001138	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
637387001139	active site
637387001140	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
637387001141	active site
637387001142	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
637387001143	active site
637387001144	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
637387001145	active site
637387001146	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
637387001147	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
637387001148	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
637387001149	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
637387001150	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
637387001151	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
637387001152	motif 1; other site
637387001153	active site
637387001154	motif 2; other site
637387001155	motif 3; other site
637387001156	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
637387001157	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
637387001158	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
637387001159	Ligand Binding Site [chemical binding]; other site
637387001160	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
637387001161	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
637387001162	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
637387001163	active site
637387001164	HIGH motif; other site
637387001165	KMSK motif region; other site
637387001166	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
637387001167	tRNA binding surface [nucleotide binding]; other site
637387001168	anticodon binding site; other site
637387001169	Amino acid permease; Region: AA_permease_2; pfam13520
637387001170	carbamate kinase; Reviewed; Region: PRK12686
637387001171	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
637387001172	putative substrate binding site [chemical binding]; other site
637387001173	nucleotide binding site [chemical binding]; other site
637387001174	nucleotide binding site [chemical binding]; other site
637387001175	homodimer interface [polypeptide binding]; other site
637387001176	ornithine carbamoyltransferase; Validated; Region: PRK02102
637387001177	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
637387001178	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
637387001179	Amidinotransferase; Region: Amidinotransf; cl12043
637387001180	Domain of unknown function(DUF2779); Region: DUF2779; pfam11074
637387001181	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
637387001182	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
637387001183	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
637387001184	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
637387001185	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
637387001186	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
637387001187	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
637387001188	active site
637387001189	Zn binding site [ion binding]; other site
637387001190	RNA methyltransferase, RsmE family; Region: TIGR00046
637387001191	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
637387001192	cell division protein FtsZ; Validated; Region: PRK09330
637387001193	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
637387001194	nucleotide binding site [chemical binding]; other site
637387001195	SulA interaction site; other site
637387001196	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
637387001197	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
637387001198	S-adenosylmethionine binding site [chemical binding]; other site
637387001199	cell division protein MraZ; Reviewed; Region: PRK00326
637387001200	MraZ protein; Region: MraZ; pfam02381
637387001201	MraZ protein; Region: MraZ; pfam02381
637387001202	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
637387001203	TrkA-N domain; Region: TrkA_N; pfam02254
637387001204	TrkA-C domain; Region: TrkA_C; pfam02080
637387001205	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
637387001206	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
637387001207	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
637387001208	transcriptional regulator MurR; Provisional; Region: PRK15482
637387001209	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
637387001210	putative active site [active]
637387001211	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
637387001212	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
637387001213	putative active site cavity [active]
637387001214	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
637387001215	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
637387001216	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
637387001217	active site turn [active]
637387001218	phosphorylation site [posttranslational modification]
637387001219	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
637387001220	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
637387001221	rRNA interaction site [nucleotide binding]; other site
637387001222	S8 interaction site; other site
637387001223	elongation factor Ts; Provisional; Region: tsf; PRK09377
637387001224	UBA/TS-N domain; Region: UBA; pfam00627
637387001225	Elongation factor TS; Region: EF_TS; pfam00889
637387001226	Elongation factor TS; Region: EF_TS; pfam00889
637387001227	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
637387001228	active site
637387001229	phosphorylation site [posttranslational modification]
637387001230	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DegV; COG1307
637387001231	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
637387001232	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
637387001233	Part of AAA domain; Region: AAA_19; pfam13245
637387001234	Family description; Region: UvrD_C_2; pfam13538
637387001235	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
637387001236	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
637387001237	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
637387001238	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
637387001239	putative dimer interface [polypeptide binding]; other site
637387001240	putative anticodon binding site; other site
637387001241	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
637387001242	motif 1; other site
637387001243	dimer interface [polypeptide binding]; other site
637387001244	active site
637387001245	motif 2; other site
637387001246	motif 3; other site
637387001247	PQ loop repeat; Region: PQ-loop; pfam04193
637387001248	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
637387001249	trimer interface [polypeptide binding]; other site
637387001250	active site
637387001251	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
637387001252	MgtE intracellular N domain; Region: MgtE_N; pfam03448
637387001253	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
637387001254	Divalent cation transporter; Region: MgtE; pfam01769
637387001255	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
637387001256	Divergent AAA domain; Region: AAA_4; pfam04326
637387001257	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
637387001258	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
637387001259	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
637387001260	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
637387001261	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387001262	Walker A/P-loop; other site
637387001263	ATP binding site [chemical binding]; other site
637387001264	Q-loop/lid; other site
637387001265	ABC transporter signature motif; other site
637387001266	Walker B; other site
637387001267	D-loop; other site
637387001268	H-loop/switch region; other site
637387001269	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
637387001270	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
637387001271	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387001272	Walker A/P-loop; other site
637387001273	ATP binding site [chemical binding]; other site
637387001274	Q-loop/lid; other site
637387001275	ABC transporter signature motif; other site
637387001276	Walker B; other site
637387001277	D-loop; other site
637387001278	H-loop/switch region; other site
637387001279	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387001280	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
637387001281	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
637387001282	active site
637387001283	motif I; other site
637387001284	motif II; other site
637387001285	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
637387001286	Protein of unknown function DUF262; Region: DUF262; pfam03235
637387001287	Uncharacterized conserved protein [Function unknown]; Region: COG1479
637387001288	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
637387001289	AAA domain; Region: AAA_14; pfam13173
637387001290	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
637387001291	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
637387001292	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
637387001293	ATP binding site [chemical binding]; other site
637387001294	putative Mg++ binding site [ion binding]; other site
637387001295	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387001296	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
637387001297	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387001298	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
637387001299	HsdM N-terminal domain; Region: HsdM_N; pfam12161
637387001300	Methyltransferase domain; Region: Methyltransf_26; pfam13659
637387001301	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387001302	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
637387001303	Fic/DOC family; Region: Fic; pfam02661
637387001304	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
637387001305	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
637387001306	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
637387001307	putative active site [active]
637387001308	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
637387001309	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
637387001310	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
637387001311	active site
637387001312	phosphorylation site [posttranslational modification]
637387001313	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
637387001314	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
637387001315	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
637387001316	active pocket/dimerization site; other site
637387001317	active site
637387001318	phosphorylation site [posttranslational modification]
637387001319	Preprotein translocase subunit; Region: YajC; cl00806
637387001320	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
637387001321	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
637387001322	NADP binding site [chemical binding]; other site
637387001323	homodimer interface [polypeptide binding]; other site
637387001324	active site
637387001325	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
637387001326	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
637387001327	active site
637387001328	intersubunit interface [polypeptide binding]; other site
637387001329	catalytic residue [active]
637387001330	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
637387001331	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
637387001332	substrate binding site [chemical binding]; other site
637387001333	ATP binding site [chemical binding]; other site
637387001334	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
637387001335	substrate binding site [chemical binding]; other site
637387001336	catalytic residues [active]
637387001337	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
637387001338	nicotinate phosphoribosyltransferase; Provisional; Region: PRK07188
637387001339	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
637387001340	active site
637387001341	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
637387001342	AAA-like domain; Region: AAA_10; pfam12846
637387001343	Zonular occludens toxin (Zot); Region: Zot; cl17485
637387001344	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
637387001345	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
637387001346	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
637387001347	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
637387001348	DNA methylase; Region: N6_N4_Mtase; cl17433
637387001349	recombination factor protein RarA; Reviewed; Region: PRK13342
637387001350	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
637387001351	RuvA N terminal domain; Region: RuvA_N; pfam01330
637387001352	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
637387001353	DNA protecting protein DprA; Region: dprA; TIGR00732
637387001354	elongation factor P; Validated; Region: PRK00529
637387001355	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
637387001356	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
637387001357	RNA binding site [nucleotide binding]; other site
637387001358	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
637387001359	RNA binding site [nucleotide binding]; other site
637387001360	LemA family; Region: LemA; cl00742
637387001361	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
637387001362	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
637387001363	putative active site [active]
637387001364	substrate binding site [chemical binding]; other site
637387001365	putative cosubstrate binding site; other site
637387001366	catalytic site [active]
637387001367	Formyl transferase, C-terminal domain; Region: Formyl_trans_C; pfam02911
637387001368	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
637387001369	AAA domain; Region: AAA_23; pfam13476
637387001370	Walker A/P-loop; other site
637387001371	ATP binding site [chemical binding]; other site
637387001372	Q-loop/lid; other site
637387001373	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
637387001374	Nsp1-like C-terminal region; Region: Nsp1_C; pfam05064
637387001375	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
637387001376	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
637387001377	ABC transporter signature motif; other site
637387001378	Walker B; other site
637387001379	D-loop; other site
637387001380	H-loop/switch region; other site
637387001381	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
637387001382	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
637387001383	dimerization interface [polypeptide binding]; other site
637387001384	active site
637387001385	metal binding site [ion binding]; metal-binding site
637387001386	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
637387001387	dsRNA binding site [nucleotide binding]; other site
637387001388	putative phosphate acyltransferase; Provisional; Region: PRK05331
637387001389	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
637387001390	DAK2 domain; Region: Dak2; pfam02734
637387001391	Recombination protein O N terminal; Region: RecO_N; pfam11967
637387001392	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecO; COG1381
637387001393	Recombination protein O C terminal; Region: RecO_C; pfam02565
637387001394	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
637387001395	dimer interface [polypeptide binding]; other site
637387001396	FMN binding site [chemical binding]; other site
637387001397	NADPH bind site [chemical binding]; other site
637387001398	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
637387001399	Sporulation Regulator WhiA C terminal domain; Region: HTH_WhiA; pfam02650
637387001400	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
637387001401	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
637387001402	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
637387001403	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
637387001404	GTP-binding protein YchF; Reviewed; Region: PRK09601
637387001405	YchF GTPase; Region: YchF; cd01900
637387001406	G1 box; other site
637387001407	GTP/Mg2+ binding site [chemical binding]; other site
637387001408	Switch I region; other site
637387001409	G2 box; other site
637387001410	Switch II region; other site
637387001411	G3 box; other site
637387001412	G4 box; other site
637387001413	G5 box; other site
637387001414	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
637387001415	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
637387001416	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
637387001417	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
637387001418	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
637387001419	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
637387001420	motif II; other site
637387001421	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
637387001422	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
637387001423	putative active site [active]
637387001424	putative catalytic site [active]
637387001425	putative Mg binding site IVb [ion binding]; other site
637387001426	putative phosphate binding site [ion binding]; other site
637387001427	putative DNA binding site [nucleotide binding]; other site
637387001428	putative Mg binding site IVa [ion binding]; other site
637387001429	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
637387001430	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
637387001431	active site
637387001432	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
637387001433	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
637387001434	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
637387001435	active site
637387001436	motif I; other site
637387001437	motif II; other site
637387001438	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
637387001439	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
637387001440	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
637387001441	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
637387001442	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
637387001443	5S rRNA interface [nucleotide binding]; other site
637387001444	L27 interface [polypeptide binding]; other site
637387001445	23S rRNA interface [nucleotide binding]; other site
637387001446	L5 interface [polypeptide binding]; other site
637387001447	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
637387001448	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
637387001449	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
637387001450	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
637387001451	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
637387001452	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
637387001453	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
637387001454	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
637387001455	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
637387001456	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
637387001457	RNA binding site [nucleotide binding]; other site
637387001458	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
637387001459	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
637387001460	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
637387001461	putative translocon interaction site; other site
637387001462	23S rRNA interface [nucleotide binding]; other site
637387001463	signal recognition particle (SRP54) interaction site; other site
637387001464	L23 interface [polypeptide binding]; other site
637387001465	trigger factor interaction site; other site
637387001466	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
637387001467	23S rRNA interface [nucleotide binding]; other site
637387001468	5S rRNA interface [nucleotide binding]; other site
637387001469	putative antibiotic binding site [chemical binding]; other site
637387001470	L25 interface [polypeptide binding]; other site
637387001471	L27 interface [polypeptide binding]; other site
637387001472	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
637387001473	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
637387001474	G-X-X-G motif; other site
637387001475	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
637387001476	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
637387001477	putative translocon binding site; other site
637387001478	protein-rRNA interface [nucleotide binding]; other site
637387001479	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
637387001480	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
637387001481	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
637387001482	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
637387001483	50S ribosomal protein L23; Reviewed; Region: rplW; PRK12280
637387001484	50S ribosomal protein L4; Provisional; Region: rplD; PRK14907
637387001485	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
637387001486	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
637387001487	recombinase A; Provisional; Region: recA; PRK09354
637387001488	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
637387001489	hexamer interface [polypeptide binding]; other site
637387001490	Walker A motif; other site
637387001491	ATP binding site [chemical binding]; other site
637387001492	Walker B motif; other site
637387001493	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
637387001494	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
637387001495	putative active site [active]
637387001496	metal binding site [ion binding]; metal-binding site
637387001497	homodimer binding site [polypeptide binding]; other site
637387001498	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
637387001499	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
637387001500	oligomer interface [polypeptide binding]; other site
637387001501	active site
637387001502	metal binding site [ion binding]; metal-binding site
637387001503	Protein of unknown function DUF45; Region: DUF45; pfam01863
637387001504	Nuclease-related domain; Region: NERD; pfam08378
637387001505	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
637387001506	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
637387001507	transcription antitermination factor NusB; Region: nusB; TIGR01951
637387001508	putative RNA binding site [nucleotide binding]; other site
637387001509	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
637387001510	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
637387001511	HIGH motif; other site
637387001512	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
637387001513	active site
637387001514	KMSKS motif; other site
637387001515	A new structural DNA glycosylase; Region: AlkD_like; cd06561
637387001516	active site
637387001517	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
637387001518	active site
637387001519	phosphorylation site [posttranslational modification]
637387001520	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
637387001521	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
637387001522	active site
637387001523	P-loop; other site
637387001524	phosphorylation site [posttranslational modification]
637387001525	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
637387001526	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
637387001527	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
637387001528	putative substrate binding site [chemical binding]; other site
637387001529	putative ATP binding site [chemical binding]; other site
637387001530	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
637387001531	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
637387001532	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
637387001533	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
637387001534	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
637387001535	dimer interface [polypeptide binding]; other site
637387001536	anticodon binding site; other site
637387001537	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
637387001538	homodimer interface [polypeptide binding]; other site
637387001539	motif 1; other site
637387001540	active site
637387001541	motif 2; other site
637387001542	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
637387001543	active site
637387001544	motif 3; other site
637387001545	histidyl-tRNA synthetase; Region: hisS; TIGR00442
637387001546	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
637387001547	dimer interface [polypeptide binding]; other site
637387001548	motif 1; other site
637387001549	active site
637387001550	motif 2; other site
637387001551	motif 3; other site
637387001552	Amino acid permease; Region: AA_permease_2; pfam13520
637387001553	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387001554	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
637387001555	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387001556	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
637387001557	Divergent AAA domain; Region: AAA_4; pfam04326
637387001558	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
637387001559	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
637387001560	dimerization interface [polypeptide binding]; other site
637387001561	putative DNA binding site [nucleotide binding]; other site
637387001562	putative Zn2+ binding site [ion binding]; other site
637387001563	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
637387001564	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
637387001565	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
637387001566	Walker A/P-loop; other site
637387001567	ATP binding site [chemical binding]; other site
637387001568	Q-loop/lid; other site
637387001569	ABC transporter signature motif; other site
637387001570	Walker B; other site
637387001571	D-loop; other site
637387001572	H-loop/switch region; other site
637387001573	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
637387001574	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
637387001575	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387001576	Walker A/P-loop; other site
637387001577	ATP binding site [chemical binding]; other site
637387001578	Q-loop/lid; other site
637387001579	ABC transporter signature motif; other site
637387001580	Walker B; other site
637387001581	D-loop; other site
637387001582	H-loop/switch region; other site
637387001583	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
637387001584	nudix motif; other site
637387001585	beta-phosphoglucomutase; Region: bPGM; TIGR01990
637387001586	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
637387001587	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
637387001588	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
637387001589	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
637387001590	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
637387001591	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
637387001592	active site
637387001593	catalytic site [active]
637387001594	pullulanase, type I; Region: pulA_typeI; TIGR02104
637387001595	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
637387001596	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
637387001597	Ca binding site [ion binding]; other site
637387001598	active site
637387001599	catalytic site [active]
637387001600	Archaeal/eukaryotic core primase: Large subunit, PriL; Region: PriL; cl11970
637387001601	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
637387001602	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
637387001603	DNA-binding site [nucleotide binding]; DNA binding site
637387001604	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
637387001605	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
637387001606	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac2_AmyA; cd11316
637387001607	Ca binding site [ion binding]; other site
637387001608	active site
637387001609	catalytic site [active]
637387001610	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
637387001611	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
637387001612	Walker A/P-loop; other site
637387001613	ATP binding site [chemical binding]; other site
637387001614	Q-loop/lid; other site
637387001615	ABC transporter signature motif; other site
637387001616	Walker B; other site
637387001617	D-loop; other site
637387001618	H-loop/switch region; other site
637387001619	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
637387001620	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387001621	dimer interface [polypeptide binding]; other site
637387001622	conserved gate region; other site
637387001623	putative PBP binding loops; other site
637387001624	ABC-ATPase subunit interface; other site
637387001625	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
637387001626	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387001627	dimer interface [polypeptide binding]; other site
637387001628	conserved gate region; other site
637387001629	putative PBP binding loops; other site
637387001630	ABC-ATPase subunit interface; other site
637387001631	potential frameshift: common BLAST hit: gi|294155941|ref|YP_003560325.1| lipoprotein
637387001632	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
637387001633	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
637387001634	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
637387001635	active site
637387001636	catalytic site [active]
637387001637	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
637387001638	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
637387001639	active site
637387001640	substrate binding site [chemical binding]; other site
637387001641	metal binding site [ion binding]; metal-binding site
637387001642	Uncharacterized conserved protein [Function unknown]; Region: COG1284
637387001643	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
637387001644	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
637387001645	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
637387001646	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
637387001647	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
637387001648	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
637387001649	NAD binding site [chemical binding]; other site
637387001650	substrate binding site [chemical binding]; other site
637387001651	catalytic Zn binding site [ion binding]; other site
637387001652	tetramer interface [polypeptide binding]; other site
637387001653	structural Zn binding site [ion binding]; other site
637387001654	DNA protecting protein DprA; Region: dprA; TIGR00732
637387001655	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
637387001656	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
637387001657	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
637387001658	active site
637387001659	motif I; other site
637387001660	motif II; other site
637387001661	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
637387001662	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
637387001663	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13651
637387001664	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
637387001665	Walker A/P-loop; other site
637387001666	ATP binding site [chemical binding]; other site
637387001667	Q-loop/lid; other site
637387001668	ABC transporter signature motif; other site
637387001669	Walker B; other site
637387001670	D-loop; other site
637387001671	H-loop/switch region; other site
637387001672	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13632
637387001673	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
637387001674	Walker A/P-loop; other site
637387001675	ATP binding site [chemical binding]; other site
637387001676	Q-loop/lid; other site
637387001677	ABC transporter signature motif; other site
637387001678	Walker B; other site
637387001679	D-loop; other site
637387001680	H-loop/switch region; other site
637387001681	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
637387001682	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
637387001683	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
637387001684	alphaNTD homodimer interface [polypeptide binding]; other site
637387001685	alphaNTD - beta interaction site [polypeptide binding]; other site
637387001686	alphaNTD - beta' interaction site [polypeptide binding]; other site
637387001687	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
637387001688	30S ribosomal protein S11; Validated; Region: PRK05309
637387001689	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
637387001690	30S ribosomal protein S13; Region: bact_S13; TIGR03631
637387001691	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
637387001692	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
637387001693	rRNA binding site [nucleotide binding]; other site
637387001694	predicted 30S ribosome binding site; other site
637387001695	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
637387001696	active site
637387001697	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
637387001698	adenylate kinase; Reviewed; Region: adk; PRK00279
637387001699	AMP-binding site [chemical binding]; other site
637387001700	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
637387001701	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
637387001702	SecY translocase; Region: SecY; pfam00344
637387001703	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
637387001704	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
637387001705	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
637387001706	Ligand Binding Site [chemical binding]; other site
637387001707	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
637387001708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387001709	dimer interface [polypeptide binding]; other site
637387001710	conserved gate region; other site
637387001711	ABC-ATPase subunit interface; other site
637387001712	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
637387001713	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387001714	dimer interface [polypeptide binding]; other site
637387001715	conserved gate region; other site
637387001716	putative PBP binding loops; other site
637387001717	ABC-ATPase subunit interface; other site
637387001718	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
637387001719	dimerization domain swap beta strand [polypeptide binding]; other site
637387001720	regulatory protein interface [polypeptide binding]; other site
637387001721	active site
637387001722	regulatory phosphorylation site [posttranslational modification]; other site
637387001723	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
637387001724	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
637387001725	Walker A/P-loop; other site
637387001726	ATP binding site [chemical binding]; other site
637387001727	Q-loop/lid; other site
637387001728	ABC transporter signature motif; other site
637387001729	Walker B; other site
637387001730	D-loop; other site
637387001731	H-loop/switch region; other site
637387001732	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
637387001733	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
637387001734	16S/18S rRNA binding site [nucleotide binding]; other site
637387001735	S13e-L30e interaction site [polypeptide binding]; other site
637387001736	25S rRNA binding site [nucleotide binding]; other site
637387001737	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
637387001738	S17 interaction site [polypeptide binding]; other site
637387001739	S8 interaction site; other site
637387001740	16S rRNA interaction site [nucleotide binding]; other site
637387001741	streptomycin interaction site [chemical binding]; other site
637387001742	23S rRNA interaction site [nucleotide binding]; other site
637387001743	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
637387001744	30S ribosomal protein S7; Validated; Region: PRK05302
637387001745	elongation factor G; Reviewed; Region: PRK12739
637387001746	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
637387001747	G1 box; other site
637387001748	putative GEF interaction site [polypeptide binding]; other site
637387001749	GTP/Mg2+ binding site [chemical binding]; other site
637387001750	Switch I region; other site
637387001751	G2 box; other site
637387001752	G3 box; other site
637387001753	Switch II region; other site
637387001754	G4 box; other site
637387001755	G5 box; other site
637387001756	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
637387001757	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
637387001758	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
637387001759	AAA domain; Region: AAA_14; pfam13173
637387001760	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387001761	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
637387001762	S-adenosylmethionine synthetase; Validated; Region: PRK05250
637387001763	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
637387001764	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
637387001765	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
637387001766	core dimer interface [polypeptide binding]; other site
637387001767	peripheral dimer interface [polypeptide binding]; other site
637387001768	L10 interface [polypeptide binding]; other site
637387001769	L11 interface [polypeptide binding]; other site
637387001770	putative EF-Tu interaction site [polypeptide binding]; other site
637387001771	putative EF-G interaction site [polypeptide binding]; other site
637387001772	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
637387001773	23S rRNA interface [nucleotide binding]; other site
637387001774	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
637387001775	Domain of unknown function DUF21; Region: DUF21; pfam01595
637387001776	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
637387001777	replicative DNA helicase; Region: DnaB; TIGR00665
637387001778	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
637387001779	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
637387001780	Walker A motif; other site
637387001781	ATP binding site [chemical binding]; other site
637387001782	Walker B motif; other site
637387001783	DNA binding loops [nucleotide binding]
637387001784	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
637387001785	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
637387001786	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
637387001787	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
637387001788	DHH family; Region: DHH; pfam01368
637387001789	Integrase core domain; Region: rve; pfam00665
637387001790	Integrase core domain; Region: rve_2; pfam13333
637387001791	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
637387001792	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
637387001793	active site
637387001794	motif I; other site
637387001795	motif II; other site
637387001796	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
637387001797	endonuclease IV; Provisional; Region: PRK01060
637387001798	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
637387001799	AP (apurinic/apyrimidinic) site pocket; other site
637387001800	DNA interaction; other site
637387001801	Metal-binding active site; metal-binding site
637387001802	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
637387001803	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
637387001804	catalytic residues [active]
637387001805	Nuclease subunit of the excinuclease complex [DNA replication, recombination, and repair]; Region: UvrC; COG0322
637387001806	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
637387001807	GIY-YIG motif/motif A; other site
637387001808	active site
637387001809	catalytic site [active]
637387001810	putative DNA binding site [nucleotide binding]; other site
637387001811	metal binding site [ion binding]; metal-binding site
637387001812	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
637387001813	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
637387001814	AAA domain; Region: AAA_14; pfam13173
637387001815	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
637387001816	Fic family protein [Function unknown]; Region: COG3177
637387001817	Fic/DOC family; Region: Fic; pfam02661
637387001818	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
637387001819	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
637387001820	Fic family protein [Function unknown]; Region: COG3177
637387001821	Fic/DOC family; Region: Fic; pfam02661
637387001822	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
637387001823	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
637387001824	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
637387001825	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
637387001826	RNA binding site [nucleotide binding]; other site
637387001827	CTP synthetase; Validated; Region: pyrG; PRK05380
637387001828	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
637387001829	Catalytic site [active]
637387001830	active site
637387001831	UTP binding site [chemical binding]; other site
637387001832	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
637387001833	active site
637387001834	putative oxyanion hole; other site
637387001835	catalytic triad [active]
637387001836	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
637387001837	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387001838	active site
637387001839	HIGH motif; other site
637387001840	nucleotide binding site [chemical binding]; other site
637387001841	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
637387001842	active site
637387001843	KMSKS motif; other site
637387001844	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
637387001845	tRNA binding surface [nucleotide binding]; other site
637387001846	anticodon binding site; other site
637387001847	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
637387001848	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
637387001849	Divergent AAA domain; Region: AAA_4; pfam04326
637387001850	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
637387001851	HTH domain; Region: HTH_11; pfam08279
637387001852	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
637387001853	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria and archaea; Region: GIY-YIG_unchar_2; cd10447
637387001854	GIY-YIG motif/motif A; other site
637387001855	putative active site [active]
637387001856	putative metal binding site [ion binding]; other site
637387001857	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
637387001858	gating phenylalanine in ion channel; other site
637387001859	C4-dicarboxylate transporter/malic acid transport protein; Region: C4dic_mal_tran; pfam03595
637387001860	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
637387001861	Helix-turn-helix domain; Region: HTH_38; pfam13936
637387001862	Integrase core domain; Region: rve; pfam00665
637387001863	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
637387001864	E3 interaction surface; other site
637387001865	lipoyl attachment site [posttranslational modification]; other site
637387001866	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
637387001867	E3 interaction surface; other site
637387001868	lipoyl attachment site [posttranslational modification]; other site
637387001869	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
637387001870	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
637387001871	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
637387001872	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
637387001873	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11857
637387001874	e3 binding domain; Region: E3_binding; pfam02817
637387001875	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
637387001876	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
637387001877	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
637387001878	alpha subunit interface [polypeptide binding]; other site
637387001879	TPP binding site [chemical binding]; other site
637387001880	heterodimer interface [polypeptide binding]; other site
637387001881	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
637387001882	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
637387001883	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
637387001884	tetramer interface [polypeptide binding]; other site
637387001885	TPP-binding site [chemical binding]; other site
637387001886	heterodimer interface [polypeptide binding]; other site
637387001887	phosphorylation loop region [posttranslational modification]
637387001888	Fic family protein [Function unknown]; Region: COG3177
637387001889	Fic/DOC family; Region: Fic; pfam02661
637387001890	Protein of unknown function (DUF402); Region: DUF402; cl00979
637387001891	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; cl17236
637387001892	5'-3' exonuclease; Provisional; Region: PRK14976
637387001893	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
637387001894	active site
637387001895	metal binding site 1 [ion binding]; metal-binding site
637387001896	putative 5' ssDNA interaction site; other site
637387001897	metal binding site 3; metal-binding site
637387001898	metal binding site 2 [ion binding]; metal-binding site
637387001899	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
637387001900	putative DNA binding site [nucleotide binding]; other site
637387001901	putative metal binding site [ion binding]; other site
637387001902	DNA polymerase III DnaE; Validated; Region: dnaE; PRK07135
637387001903	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
637387001904	active site
637387001905	PHP Thumb interface [polypeptide binding]; other site
637387001906	OB-fold nucleic acid binding domain; Region: tRNA_anti; pfam01336
637387001907	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
637387001908	ribosome recycling factor; Reviewed; Region: frr; PRK00083
637387001909	hinge region; other site
637387001910	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
637387001911	putative nucleotide binding site [chemical binding]; other site
637387001912	uridine monophosphate binding site [chemical binding]; other site
637387001913	homohexameric interface [polypeptide binding]; other site
637387001914	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
637387001915	nucleotide binding site/active site [active]
637387001916	HIT family signature motif; other site
637387001917	catalytic residue [active]
637387001918	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
637387001919	IHF - DNA interface [nucleotide binding]; other site
637387001920	IHF dimer interface [polypeptide binding]; other site
637387001921	Recombination protein U; Region: RecU; cl01314
637387001922	Competence protein; Region: Competence; cl00471
637387001923	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
637387001924	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
637387001925	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
637387001926	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
637387001927	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
637387001928	S-adenosylmethionine binding site [chemical binding]; other site
637387001929	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
637387001930	active site
637387001931	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
637387001932	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
637387001933	trmE is a tRNA modification GTPase; Region: trmE; cd04164
637387001934	G1 box; other site
637387001935	GTP/Mg2+ binding site [chemical binding]; other site
637387001936	Switch I region; other site
637387001937	G2 box; other site
637387001938	Switch II region; other site
637387001939	G3 box; other site
637387001940	G4 box; other site
637387001941	G5 box; other site
637387001942	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
637387001943	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
637387001944	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
637387001945	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
637387001946	active site turn [active]
637387001947	phosphorylation site [posttranslational modification]
637387001948	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
637387001949	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
637387001950	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
637387001951	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
637387001952	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
637387001953	active site
637387001954	HIGH motif; other site
637387001955	KMSKS motif; other site
637387001956	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
637387001957	tRNA binding surface [nucleotide binding]; other site
637387001958	anticodon binding site; other site
637387001959	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
637387001960	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
637387001961	S-adenosylmethionine binding site [chemical binding]; other site
637387001962	ribonuclease R; Region: RNase_R; TIGR02063
637387001963	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
637387001964	RNB domain; Region: RNB; pfam00773
637387001965	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
637387001966	RNA binding site [nucleotide binding]; other site
637387001967	Guanylate kinase; Region: Guanylate_kin; pfam00625
637387001968	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
637387001969	catalytic site [active]
637387001970	G-X2-G-X-G-K; other site
637387001971	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
637387001972	active site
637387001973	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
637387001974	Catalytic domain of Protein Kinases; Region: PKc; cd00180
637387001975	active site
637387001976	ATP binding site [chemical binding]; other site
637387001977	substrate binding site [chemical binding]; other site
637387001978	activation loop (A-loop); other site
637387001979	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
637387001980	ribosome small subunit-dependent GTPase A; Region: TIGR00157
637387001981	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
637387001982	GTPase/Zn-binding domain interface [polypeptide binding]; other site
637387001983	GTP/Mg2+ binding site [chemical binding]; other site
637387001984	G4 box; other site
637387001985	G5 box; other site
637387001986	G1 box; other site
637387001987	Switch I region; other site
637387001988	G2 box; other site
637387001989	G3 box; other site
637387001990	Switch II region; other site
637387001991	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
637387001992	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
637387001993	substrate binding site [chemical binding]; other site
637387001994	hexamer interface [polypeptide binding]; other site
637387001995	metal binding site [ion binding]; metal-binding site
637387001996	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
637387001997	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
637387001998	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
637387001999	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
637387002000	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
637387002001	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
637387002002	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
637387002003	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
637387002004	Hpr binding site; other site
637387002005	active site
637387002006	homohexamer subunit interaction site [polypeptide binding]; other site
637387002007	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
637387002008	Helix-turn-helix domain; Region: HTH_38; pfam13936
637387002009	Integrase core domain; Region: rve; pfam00665
637387002010	PBP superfamily domain; Region: PBP_like_2; cl17296
637387002011	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387002012	dimer interface [polypeptide binding]; other site
637387002013	conserved gate region; other site
637387002014	putative PBP binding loops; other site
637387002015	ABC-ATPase subunit interface; other site
637387002016	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
637387002017	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387002018	dimer interface [polypeptide binding]; other site
637387002019	conserved gate region; other site
637387002020	putative PBP binding loops; other site
637387002021	ABC-ATPase subunit interface; other site
637387002022	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
637387002023	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
637387002024	Walker A/P-loop; other site
637387002025	ATP binding site [chemical binding]; other site
637387002026	Q-loop/lid; other site
637387002027	ABC transporter signature motif; other site
637387002028	Walker B; other site
637387002029	D-loop; other site
637387002030	H-loop/switch region; other site
637387002031	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
637387002032	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
637387002033	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
637387002034	interface (dimer of trimers) [polypeptide binding]; other site
637387002035	Substrate-binding/catalytic site; other site
637387002036	Zn-binding sites [ion binding]; other site
637387002037	thymidine kinase; Provisional; Region: PRK04296
637387002038	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
637387002039	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
637387002040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387002041	dimer interface [polypeptide binding]; other site
637387002042	conserved gate region; other site
637387002043	putative PBP binding loops; other site
637387002044	ABC-ATPase subunit interface; other site
637387002045	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
637387002046	dimer interface [polypeptide binding]; other site
637387002047	conserved gate region; other site
637387002048	putative PBP binding loops; other site
637387002049	ABC-ATPase subunit interface; other site
637387002050	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387002051	AAA domain; Region: AAA_21; pfam13304
637387002052	Walker A/P-loop; other site
637387002053	ATP binding site [chemical binding]; other site
637387002054	Q-loop/lid; other site
637387002055	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
637387002056	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387002057	ABC transporter signature motif; other site
637387002058	Walker B; other site
637387002059	D-loop; other site
637387002060	H-loop/switch region; other site
637387002061	TOBE domain; Region: TOBE_2; pfam08402
637387002062	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
637387002063	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
637387002064	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
637387002065	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
637387002066	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
637387002067	Protein of unknown function (DUF1640); Region: DUF1640; pfam07798
637387002068	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
637387002069	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387002070	active site
637387002071	HIGH motif; other site
637387002072	nucleotide binding site [chemical binding]; other site
637387002073	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
637387002074	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387002075	Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: CysS; COG0215
637387002076	active site
637387002077	HIGH motif; other site
637387002078	nucleotide binding site [chemical binding]; other site
637387002079	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
637387002080	active site
637387002081	KMSKS motif; other site
637387002082	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
637387002083	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
637387002084	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
637387002085	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
637387002086	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
637387002087	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
637387002088	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
637387002089	putative homodimer interface [polypeptide binding]; other site
637387002090	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
637387002091	heterodimer interface [polypeptide binding]; other site
637387002092	homodimer interface [polypeptide binding]; other site
637387002093	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
637387002094	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; cl17726
637387002095	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
637387002096	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
637387002097	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
637387002098	active site
637387002099	peptide chain release factor 1; Validated; Region: prfA; PRK00591
637387002100	This domain is found in peptide chain release factors; Region: PCRF; smart00937
637387002101	RF-1 domain; Region: RF-1; pfam00472
637387002102	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
637387002103	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
637387002104	S-adenosylmethionine binding site [chemical binding]; other site
637387002105	acyl carrier protein; Provisional; Region: acpP; PRK00982
637387002106	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
637387002107	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
637387002108	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
637387002109	Helix-turn-helix domain; Region: HTH_38; pfam13936
637387002110	Integrase core domain; Region: rve; pfam00665
637387002111	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
637387002112	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
637387002113	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387002114	Walker A/P-loop; other site
637387002115	ATP binding site [chemical binding]; other site
637387002116	Q-loop/lid; other site
637387002117	ABC transporter signature motif; other site
637387002118	Walker B; other site
637387002119	D-loop; other site
637387002120	H-loop/switch region; other site
637387002121	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
637387002122	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387002123	Walker A motif; other site
637387002124	ATP binding site [chemical binding]; other site
637387002125	Walker B motif; other site
637387002126	arginine finger; other site
637387002127	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
637387002128	recombination protein RecR; Reviewed; Region: recR; PRK00076
637387002129	RecR protein; Region: RecR; pfam02132
637387002130	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
637387002131	active site
637387002132	metal binding site [ion binding]; metal-binding site
637387002133	thymidylate kinase; Validated; Region: tmk; PRK00698
637387002134	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
637387002135	TMP-binding site; other site
637387002136	ATP-binding site [chemical binding]; other site
637387002137	DNA polymerase III subunit delta'; Validated; Region: PRK07132
637387002138	DNA polymerase III subunit delta'; Validated; Region: PRK08485
637387002139	Predicted methyltransferases [General function prediction only]; Region: COG0313
637387002140	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
637387002141	putative SAM binding site [chemical binding]; other site
637387002142	putative homodimer interface [polypeptide binding]; other site
637387002143	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
637387002144	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
637387002145	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
637387002146	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
637387002147	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
637387002148	Helix-turn-helix domain; Region: HTH_38; pfam13936
637387002149	Integrase core domain; Region: rve; pfam00665
637387002150	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
637387002151	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387002152	Walker A/P-loop; other site
637387002153	ATP binding site [chemical binding]; other site
637387002154	Q-loop/lid; other site
637387002155	ABC transporter signature motif; other site
637387002156	Walker B; other site
637387002157	D-loop; other site
637387002158	H-loop/switch region; other site
637387002159	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
637387002160	Walker A/P-loop; other site
637387002161	ATP binding site [chemical binding]; other site
637387002162	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
637387002163	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
637387002164	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
637387002165	TM-ABC transporter signature motif; other site
637387002166	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
637387002167	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
637387002168	TM-ABC transporter signature motif; other site
637387002169	DNA polymerase III PolC; Validated; Region: polC; PRK00448
637387002170	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
637387002171	catalytic residues [active]
637387002172	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
637387002173	Transcriptional regulators [Transcription]; Region: PurR; COG1609
637387002174	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
637387002175	DNA binding site [nucleotide binding]
637387002176	domain linker motif; other site
637387002177	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
637387002178	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
637387002179	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
637387002180	ATP binding site [chemical binding]; other site
637387002181	Mg2+ binding site [ion binding]; other site
637387002182	G-X-G motif; other site
637387002183	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
637387002184	anchoring element; other site
637387002185	dimer interface [polypeptide binding]; other site
637387002186	ATP binding site [chemical binding]; other site
637387002187	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
637387002188	active site
637387002189	putative metal-binding site [ion binding]; other site
637387002190	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
637387002191	Uncharacterized conserved protein [Function unknown]; Region: COG1284
637387002192	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
637387002193	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
637387002194	seryl-tRNA synthetase; Provisional; Region: PRK05431
637387002195	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
637387002196	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
637387002197	dimer interface [polypeptide binding]; other site
637387002198	active site
637387002199	motif 1; other site
637387002200	motif 2; other site
637387002201	motif 3; other site
637387002202	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
637387002203	RNase P protein component [Translation, ribosomal structure and biogenesis]; Region: RnpA; COG0594
637387002204	putative inner membrane protein translocase component YidC; Provisional; Region: PRK02201
637387002205	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
637387002206	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
637387002207	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
637387002208	TPP-binding site [chemical binding]; other site
637387002209	dimer interface [polypeptide binding]; other site
637387002210	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
637387002211	PYR/PP interface [polypeptide binding]; other site
637387002212	dimer interface [polypeptide binding]; other site
637387002213	TPP binding site [chemical binding]; other site
637387002214	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
637387002215	TM2 domain; Region: TM2; pfam05154
637387002216	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
637387002217	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
637387002218	Double zinc ribbon; Region: DZR; pfam12773
637387002219	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
637387002220	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
637387002221	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
637387002222	RNA/DNA hybrid binding site [nucleotide binding]; other site
637387002223	active site
637387002224	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
637387002225	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
637387002226	RNA binding surface [nucleotide binding]; other site
637387002227	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
637387002228	active site
637387002229	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
637387002230	Chromate transporter; Region: Chromate_transp; pfam02417
637387002231	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
637387002232	NAD(P) binding site [chemical binding]; other site
637387002233	catalytic residues [active]
637387002234	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
637387002235	D-allose kinase; Provisional; Region: PRK09698
637387002236	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
637387002237	nucleotide binding site [chemical binding]; other site
637387002238	Ion channel; Region: Ion_trans_2; pfam07885
637387002239	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
637387002240	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
637387002241	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
637387002242	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
637387002243	S-adenosylmethionine binding site [chemical binding]; other site
637387002244	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
637387002245	non-specific DNA binding site [nucleotide binding]; other site
637387002246	salt bridge; other site
637387002247	sequence-specific DNA binding site [nucleotide binding]; other site
637387002248	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
637387002249	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
637387002250	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
637387002251	ATP binding site [chemical binding]; other site
637387002252	putative Mg++ binding site [ion binding]; other site
637387002253	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
637387002254	Methyltransferase domain; Region: Methyltransf_26; pfam13659
637387002255	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387002256	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
637387002257	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
637387002258	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387002259	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
637387002260	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
637387002261	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
637387002262	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
637387002263	catalytic residues [active]
637387002264	catalytic nucleophile [active]
637387002265	Presynaptic Site I dimer interface [polypeptide binding]; other site
637387002266	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
637387002267	Synaptic Flat tetramer interface [polypeptide binding]; other site
637387002268	Synaptic Site I dimer interface [polypeptide binding]; other site
637387002269	DNA binding site [nucleotide binding]
637387002270	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387002271	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
637387002272	Walker A motif; other site
637387002273	ATP binding site [chemical binding]; other site
637387002274	Walker B motif; other site
637387002275	arginine finger; other site
637387002276	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387002277	Walker A motif; other site
637387002278	ATP binding site [chemical binding]; other site
637387002279	Walker B motif; other site
637387002280	arginine finger; other site
637387002281	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
637387002282	DNA polymerase III PolC; Validated; Region: polC; PRK00448
637387002283	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
637387002284	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
637387002285	generic binding surface II; other site
637387002286	generic binding surface I; other site
637387002287	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
637387002288	active site
637387002289	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
637387002290	active site
637387002291	catalytic site [active]
637387002292	substrate binding site [chemical binding]; other site
637387002293	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
637387002294	prolyl-tRNA synthetase; Provisional; Region: PRK08661
637387002295	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
637387002296	dimer interface [polypeptide binding]; other site
637387002297	motif 1; other site
637387002298	active site
637387002299	motif 2; other site
637387002300	motif 3; other site
637387002301	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
637387002302	anticodon binding site; other site
637387002303	zinc-binding site [ion binding]; other site
637387002304	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
637387002305	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
637387002306	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
637387002307	Transglutaminase/protease-like homologues; Region: TGc; smart00460
637387002308	inorganic pyrophosphatase; Provisional; Region: PRK02230
637387002309	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
637387002310	dimer interface [polypeptide binding]; other site
637387002311	substrate binding site [chemical binding]; other site
637387002312	metal binding sites [ion binding]; metal-binding site
637387002313	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
637387002314	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
637387002315	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
637387002316	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
637387002317	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
637387002318	Walker A/P-loop; other site
637387002319	ATP binding site [chemical binding]; other site
637387002320	Q-loop/lid; other site
637387002321	ABC transporter signature motif; other site
637387002322	Walker B; other site
637387002323	D-loop; other site
637387002324	H-loop/switch region; other site
637387002325	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
637387002326	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
637387002327	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
637387002328	50S ribosomal protein L11/unknown domain fusion protein; Provisional; Region: PRK14539
637387002329	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
637387002330	23S rRNA interface [nucleotide binding]; other site
637387002331	L7/L12 interface [polypeptide binding]; other site
637387002332	putative thiostrepton binding site; other site
637387002333	L25 interface [polypeptide binding]; other site
637387002334	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
637387002335	mRNA/rRNA interface [nucleotide binding]; other site
637387002336	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
637387002337	active site
637387002338	metal-binding site
637387002339	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
637387002340	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
637387002341	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
637387002342	catalytic residue [active]
637387002343	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
637387002344	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
637387002345	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
637387002346	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
637387002347	Walker A/P-loop; other site
637387002348	ATP binding site [chemical binding]; other site
637387002349	Q-loop/lid; other site
637387002350	ABC transporter signature motif; other site
637387002351	Walker B; other site
637387002352	D-loop; other site
637387002353	H-loop/switch region; other site
637387002354	FtsX-like permease family; Region: FtsX; pfam02687
637387002355	FtsX-like permease family; Region: FtsX; pfam02687
637387002356	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
637387002357	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
637387002358	Walker A motif; other site
637387002359	ATP binding site [chemical binding]; other site
637387002360	Walker B motif; other site
637387002361	arginine finger; other site
637387002362	Peptidase family M41; Region: Peptidase_M41; pfam01434
637387002363	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
637387002364	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
637387002365	Ligand Binding Site [chemical binding]; other site
637387002366	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
637387002367	putative active site [active]
637387002368	catalytic residue [active]
637387002369	Family description; Region: UvrD_C_2; pfam13538
637387002370	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
637387002371	AAA domain; Region: AAA_30; pfam13604
637387002372	Family description; Region: UvrD_C_2; pfam13538