-- dump date   	20140619_160050
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
943945000001	Putative DnaA box
943945000002	Putative DnaA box
943945000003	Putative DnaA box
943945000004	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
943945000005	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945000006	Walker A motif; other site
943945000007	ATP binding site [chemical binding]; other site
943945000008	Walker B motif; other site
943945000009	arginine finger; other site
943945000010	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
943945000011	DnaA box-binding interface [nucleotide binding]; other site
943945000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cl17512
943945000013	DNA polymerase III subunit beta; Provisional; Region: PRK14946
943945000014	putative DNA binding surface [nucleotide binding]; other site
943945000015	dimer interface [polypeptide binding]; other site
943945000016	beta-clamp/clamp loader binding surface; other site
943945000017	beta-clamp/translesion DNA polymerase binding surface; other site
943945000018	S4 domain; Region: S4_2; pfam13275
943945000019	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
943945000020	catalytic motif [active]
943945000021	Zn binding site [ion binding]; other site
943945000022	EDD domain protein, DegV family; Region: DegV; TIGR00762
943945000023	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
943945000024	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
943945000025	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
943945000026	active site
943945000027	HIGH motif; other site
943945000028	dimer interface [polypeptide binding]; other site
943945000029	KMSKS motif; other site
943945000030	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
943945000031	amphipathic channel; other site
943945000032	Asn-Pro-Ala signature motifs; other site
943945000033	NAD synthetase; Provisional; Region: PRK13980
943945000034	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
943945000035	homodimer interface [polypeptide binding]; other site
943945000036	NAD binding pocket [chemical binding]; other site
943945000037	ATP binding pocket [chemical binding]; other site
943945000038	Mg binding site [ion binding]; other site
943945000039	active-site loop [active]
943945000040	hypothetical protein; Validated; Region: PRK00110
943945000041	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
943945000042	putative phosphoketolase; Provisional; Region: PRK05261
943945000043	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
943945000044	TPP-binding site; other site
943945000045	XFP C-terminal domain; Region: XFP_C; pfam09363
943945000046	Methyltransferase domain; Region: Methyltransf_26; pfam13659
943945000047	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
943945000048	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
943945000049	Helix-turn-helix domain; Region: HTH_28; pfam13518
943945000050	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
943945000051	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
943945000052	dimer interface [polypeptide binding]; other site
943945000053	putative anticodon binding site; other site
943945000054	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
943945000055	motif 1; other site
943945000056	active site
943945000057	motif 2; other site
943945000058	motif 3; other site
943945000059	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
943945000060	active site
943945000061	substrate binding pocket [chemical binding]; other site
943945000062	homodimer interaction site [polypeptide binding]; other site
943945000063	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
943945000064	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
943945000065	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
943945000066	active site
943945000067	phosphorylation site [posttranslational modification]
943945000068	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
943945000069	active site
943945000070	dimer interface [polypeptide binding]; other site
943945000071	magnesium binding site [ion binding]; other site
943945000072	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
943945000073	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
943945000074	AP (apurinic/apyrimidinic) site pocket; other site
943945000075	DNA interaction; other site
943945000076	Metal-binding active site; metal-binding site
943945000077	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
943945000078	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
943945000079	intersubunit interface [polypeptide binding]; other site
943945000080	active site
943945000081	Zn2+ binding site [ion binding]; other site
943945000082	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
943945000083	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
943945000084	active site
943945000085	motif I; other site
943945000086	motif II; other site
943945000087	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
943945000088	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
943945000089	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
943945000090	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
943945000091	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
943945000092	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
943945000093	active site turn [active]
943945000094	phosphorylation site [posttranslational modification]
943945000095	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
943945000096	HPr interaction site; other site
943945000097	glycerol kinase (GK) interaction site [polypeptide binding]; other site
943945000098	active site
943945000099	phosphorylation site [posttranslational modification]
943945000100	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
943945000101	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
943945000102	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
943945000103	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
943945000104	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
943945000105	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
943945000106	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
943945000107	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
943945000108	active site
943945000109	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
943945000110	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
943945000111	NAD binding site [chemical binding]; other site
943945000112	homodimer interface [polypeptide binding]; other site
943945000113	active site
943945000114	substrate binding site [chemical binding]; other site
943945000115	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
943945000116	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
943945000117	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
943945000118	DXD motif; other site
943945000119	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cl00425
943945000120	phosphate binding site [ion binding]; other site
943945000121	dimer interface [polypeptide binding]; other site
943945000122	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
943945000123	active site
943945000124	potential frameshift: common BLAST hit: gi|308190214|ref|YP_003923145.1| transposase for IS1630-like insertion sequence element
943945000125	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
943945000126	Integrase core domain; Region: rve; pfam00665
943945000127	Helix-turn-helix domain; Region: HTH_38; pfam13936
943945000128	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
943945000129	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000130	Walker A/P-loop; other site
943945000131	ATP binding site [chemical binding]; other site
943945000132	Q-loop/lid; other site
943945000133	ABC transporter signature motif; other site
943945000134	Walker B; other site
943945000135	D-loop; other site
943945000136	H-loop/switch region; other site
943945000137	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
943945000138	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
943945000139	P loop; other site
943945000140	GTP binding site [chemical binding]; other site
943945000141	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
943945000142	DNA binding residues [nucleotide binding]
943945000143	AAA domain; Region: AAA_14; pfam13173
943945000144	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945000145	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
943945000146	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
943945000147	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
943945000148	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
943945000149	putative active site [active]
943945000150	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
943945000151	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
943945000152	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
943945000153	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
943945000154	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
943945000155	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
943945000156	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
943945000157	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
943945000158	DHH family; Region: DHH; pfam01368
943945000159	DHHA1 domain; Region: DHHA1; pfam02272
943945000160	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
943945000161	DHH family; Region: DHH; pfam01368
943945000162	DHHA1 domain; Region: DHHA1; pfam02272
943945000163	hypothetical protein; Provisional; Region: PRK14644
943945000164	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
943945000165	Sm and related proteins; Region: Sm_like; cl00259
943945000166	heptamer interface [polypeptide binding]; other site
943945000167	Sm1 motif; other site
943945000168	hexamer interface [polypeptide binding]; other site
943945000169	RNA binding site [nucleotide binding]; other site
943945000170	Sm2 motif; other site
943945000171	transcription termination factor NusA; Region: NusA; TIGR01953
943945000172	NusA N-terminal domain; Region: NusA_N; pfam08529
943945000173	NusA-like KH domain; Region: KH_5; pfam13184
943945000174	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
943945000175	G-X-X-G motif; other site
943945000176	Protein of unknown function (DUF448); Region: DUF448; pfam04296
943945000177	putative RNA binding cleft [nucleotide binding]; other site
943945000178	translation initiation factor IF-2; Region: IF-2; TIGR00487
943945000179	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
943945000180	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
943945000181	G1 box; other site
943945000182	putative GEF interaction site [polypeptide binding]; other site
943945000183	GTP/Mg2+ binding site [chemical binding]; other site
943945000184	Switch I region; other site
943945000185	G2 box; other site
943945000186	G3 box; other site
943945000187	Switch II region; other site
943945000188	G4 box; other site
943945000189	G5 box; other site
943945000190	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
943945000191	Translation-initiation factor 2; Region: IF-2; pfam11987
943945000192	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
943945000193	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
943945000194	active site
943945000195	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
943945000196	Helix-turn-helix domain; Region: HTH_38; pfam13936
943945000197	Integrase core domain; Region: rve; pfam00665
943945000198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945000199	Walker A motif; other site
943945000200	ATP binding site [chemical binding]; other site
943945000201	Walker B motif; other site
943945000202	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
943945000203	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
943945000204	CoA-binding site [chemical binding]; other site
943945000205	ATP-binding [chemical binding]; other site
943945000206	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
943945000207	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
943945000208	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
943945000209	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
943945000210	putative active site [active]
943945000211	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
943945000212	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
943945000213	Walker A/P-loop; other site
943945000214	ATP binding site [chemical binding]; other site
943945000215	Q-loop/lid; other site
943945000216	ABC transporter signature motif; other site
943945000217	Walker B; other site
943945000218	D-loop; other site
943945000219	H-loop/switch region; other site
943945000220	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
943945000221	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
943945000222	active site
943945000223	catalytic motif [active]
943945000224	Zn binding site [ion binding]; other site
943945000225	GTPase Era; Reviewed; Region: era; PRK00089
943945000226	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
943945000227	G1 box; other site
943945000228	GTP/Mg2+ binding site [chemical binding]; other site
943945000229	Switch I region; other site
943945000230	G2 box; other site
943945000231	Switch II region; other site
943945000232	G3 box; other site
943945000233	G4 box; other site
943945000234	G5 box; other site
943945000235	KH domain; Region: KH_2; pfam07650
943945000236	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
943945000237	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
943945000238	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
943945000239	active site
943945000240	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
943945000241	TRAM domain; Region: TRAM; cl01282
943945000242	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
943945000243	S-adenosylmethionine binding site [chemical binding]; other site
943945000244	DNA protecting protein DprA; Region: dprA; TIGR00732
943945000245	RuvA N terminal domain; Region: RuvA_N; pfam01330
943945000246	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
943945000247	helix-hairpin-helix signature motif; other site
943945000248	active site
943945000249	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
943945000250	recombination factor protein RarA; Reviewed; Region: PRK13342
943945000251	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
943945000252	DNA methylase; Region: N6_N4_Mtase; cl17433
943945000253	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945000254	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945000255	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945000256	AAA-like domain; Region: AAA_10; pfam12846
943945000257	Domain of unknown function DUF87; Region: DUF87; pfam01935
943945000258	Zonular occludens toxin (Zot); Region: Zot; cl17485
943945000259	Homeodomain-like domain; Region: HTH_23; pfam13384
943945000260	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
943945000261	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
943945000262	S-adenosylmethionine binding site [chemical binding]; other site
943945000263	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
943945000264	active site
943945000265	catalytic residues [active]
943945000266	metal binding site [ion binding]; metal-binding site
943945000267	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit [DNA replication, recombination, and repair]; Region: GyrB; COG0187
943945000268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
943945000269	Mg2+ binding site [ion binding]; other site
943945000270	G-X-G motif; other site
943945000271	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
943945000272	anchoring element; other site
943945000273	dimer interface [polypeptide binding]; other site
943945000274	ATP binding site [chemical binding]; other site
943945000275	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
943945000276	active site
943945000277	putative metal-binding site [ion binding]; other site
943945000278	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
943945000279	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
943945000280	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
943945000281	CAP-like domain; other site
943945000282	active site
943945000283	primary dimer interface [polypeptide binding]; other site
943945000284	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
943945000285	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
943945000286	active site
943945000287	metal binding site [ion binding]; metal-binding site
943945000288	homotetramer interface [polypeptide binding]; other site
943945000289	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
943945000290	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
943945000291	active site
943945000292	motif I; other site
943945000293	motif II; other site
943945000294	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
943945000295	Ribonuclease HIII [DNA replication, recombination, and repair]; Region: RnhC; COG1039
943945000296	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
943945000297	RNA/DNA hybrid binding site [nucleotide binding]; other site
943945000298	active site
943945000299	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
943945000300	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
943945000301	nucleotide binding site [chemical binding]; other site
943945000302	recombination factor protein RarA; Reviewed; Region: PRK13342
943945000303	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945000304	Walker A motif; other site
943945000305	ATP binding site [chemical binding]; other site
943945000306	Walker B motif; other site
943945000307	arginine finger; other site
943945000308	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
943945000309	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
943945000310	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
943945000311	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
943945000312	dimer interface [polypeptide binding]; other site
943945000313	motif 1; other site
943945000314	active site
943945000315	motif 2; other site
943945000316	motif 3; other site
943945000317	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
943945000318	ligand binding site [chemical binding]; other site
943945000319	active site
943945000320	UGI interface [polypeptide binding]; other site
943945000321	catalytic site [active]
943945000322	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
943945000323	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
943945000324	putative tRNA-binding site [nucleotide binding]; other site
943945000325	B3/4 domain; Region: B3_4; pfam03483
943945000326	tRNA synthetase B5 domain; Region: B5; pfam03484
943945000327	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
943945000328	motif 1; other site
943945000329	dimer interface [polypeptide binding]; other site
943945000330	active site
943945000331	motif 2; other site
943945000332	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
943945000333	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
943945000334	dimer interface [polypeptide binding]; other site
943945000335	active site
943945000336	glycine-pyridoxal phosphate binding site [chemical binding]; other site
943945000337	folate binding site [chemical binding]; other site
943945000338	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
943945000339	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
943945000340	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
943945000341	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
943945000342	HSP70 interaction site [polypeptide binding]; other site
943945000343	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
943945000344	Zn binding sites [ion binding]; other site
943945000345	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
943945000346	dimer interface [polypeptide binding]; other site
943945000347	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
943945000348	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
943945000349	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
943945000350	putative acyl-acceptor binding pocket; other site
943945000351	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
943945000352	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
943945000353	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
943945000354	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
943945000355	RNA binding surface [nucleotide binding]; other site
943945000356	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
943945000357	active site
943945000358	amidase; Provisional; Region: PRK07139
943945000359	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
943945000360	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
943945000361	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
943945000362	GatB domain; Region: GatB_Yqey; smart00845
943945000363	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
943945000364	DpnII restriction endonuclease; Region: DpnII; pfam04556
943945000365	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
943945000366	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
943945000367	non-specific DNA binding site [nucleotide binding]; other site
943945000368	salt bridge; other site
943945000369	sequence-specific DNA binding site [nucleotide binding]; other site
943945000370	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
943945000371	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
943945000372	Divergent AAA domain; Region: AAA_4; pfam04326
943945000373	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
943945000374	Helix-turn-helix domain; Region: HTH_36; pfam13730
943945000375	oligoendopeptidase F; Region: pepF; TIGR00181
943945000376	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
943945000377	active site
943945000378	Zn binding site [ion binding]; other site
943945000379	trigger factor; Region: tig; TIGR00115
943945000380	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
943945000381	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
943945000382	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
943945000383	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
943945000384	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
943945000385	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
943945000386	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
943945000387	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
943945000388	GTP/Mg2+ binding site [chemical binding]; other site
943945000389	G4 box; other site
943945000390	G5 box; other site
943945000391	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
943945000392	G1 box; other site
943945000393	G1 box; other site
943945000394	GTP/Mg2+ binding site [chemical binding]; other site
943945000395	Switch I region; other site
943945000396	G2 box; other site
943945000397	G2 box; other site
943945000398	G3 box; other site
943945000399	G3 box; other site
943945000400	Switch II region; other site
943945000401	Switch II region; other site
943945000402	G4 box; other site
943945000403	potential frameshift: common BLAST hit: gi|308189706|ref|YP_003922637.1| putative ABC transporter
943945000404	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000405	Walker A/P-loop; other site
943945000406	ATP binding site [chemical binding]; other site
943945000407	ABC transporter; Region: ABC_tran; pfam00005
943945000408	Q-loop/lid; other site
943945000409	ABC transporter signature motif; other site
943945000410	Walker B; other site
943945000411	D-loop; other site
943945000412	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000413	H-loop/switch region; other site
943945000414	ABC-2 type transporter; Region: ABC2_membrane; cl17235
943945000415	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
943945000416	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
943945000417	dimer interface [polypeptide binding]; other site
943945000418	catalytic triad [active]
943945000419	peroxidatic and resolving cysteines [active]
943945000420	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
943945000421	GTP-binding protein Der; Reviewed; Region: PRK00093
943945000422	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
943945000423	G1 box; other site
943945000424	GTP/Mg2+ binding site [chemical binding]; other site
943945000425	Switch I region; other site
943945000426	G2 box; other site
943945000427	Switch II region; other site
943945000428	G3 box; other site
943945000429	G4 box; other site
943945000430	G5 box; other site
943945000431	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
943945000432	G1 box; other site
943945000433	GTP/Mg2+ binding site [chemical binding]; other site
943945000434	Switch I region; other site
943945000435	G2 box; other site
943945000436	G3 box; other site
943945000437	Switch II region; other site
943945000438	G4 box; other site
943945000439	G5 box; other site
943945000440	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
943945000441	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
943945000442	CMP-binding site; other site
943945000443	The sites determining sugar specificity; other site
943945000444	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
943945000445	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
943945000446	RNA binding surface [nucleotide binding]; other site
943945000447	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
943945000448	active site
943945000449	putative nicotinate-nucleotide adenylyltransferase; Validated; Region: nadD; PRK07152
943945000450	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
943945000451	active site
943945000452	(T/H)XGH motif; other site
943945000453	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
943945000454	Zn2+ binding site [ion binding]; other site
943945000455	Mg2+ binding site [ion binding]; other site
943945000456	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
943945000457	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
943945000458	active site
943945000459	DNA binding site [nucleotide binding]
943945000460	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
943945000461	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
943945000462	trimerization site [polypeptide binding]; other site
943945000463	active site
943945000464	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
943945000465	Aminotransferase class-V; Region: Aminotran_5; pfam00266
943945000466	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
943945000467	catalytic residue [active]
943945000468	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
943945000469	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
943945000470	LicD family; Region: LicD; pfam04991
943945000471	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
943945000472	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
943945000473	NAD binding site [chemical binding]; other site
943945000474	Membrane transport protein; Region: Mem_trans; cl09117
943945000475	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
943945000476	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
943945000477	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
943945000478	active site
943945000479	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
943945000480	Phosphotransferase enzyme family; Region: APH; pfam01636
943945000481	active site
943945000482	substrate binding site [chemical binding]; other site
943945000483	ATP binding site [chemical binding]; other site
943945000484	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
943945000485	23S rRNA interface [nucleotide binding]; other site
943945000486	L3 interface [polypeptide binding]; other site
943945000487	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
943945000488	LicD family; Region: LicD; pfam04991
943945000489	hypothetical protein; Provisional; Region: PRK09609
943945000490	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; cl01319
943945000491	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
943945000492	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
943945000493	intersubunit interface [polypeptide binding]; other site
943945000494	active site
943945000495	zinc binding site [ion binding]; other site
943945000496	Na+ binding site [ion binding]; other site
943945000497	Staphylococcal nuclease homologues; Region: SNc; smart00318
943945000498	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
943945000499	Catalytic site; other site
943945000500	pyruvate kinase; Provisional; Region: PRK05826
943945000501	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
943945000502	domain interfaces; other site
943945000503	active site
943945000504	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
943945000505	G1 box; other site
943945000506	GTP/Mg2+ binding site [chemical binding]; other site
943945000507	Switch I region; other site
943945000508	G2 box; other site
943945000509	G3 box; other site
943945000510	Switch II region; other site
943945000511	G4 box; other site
943945000512	G5 box; other site
943945000513	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK13964
943945000514	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945000515	active site
943945000516	nucleotide binding site [chemical binding]; other site
943945000517	HIGH motif; other site
943945000518	KMSKS motif; other site
943945000519	Acetokinase family; Region: Acetate_kinase; cl17229
943945000520	propionate/acetate kinase; Provisional; Region: PRK12379
943945000521	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
943945000522	Integrase core domain; Region: rve_3; cl15866
943945000523	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
943945000524	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
943945000525	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
943945000526	homodimer interface [polypeptide binding]; other site
943945000527	NADP binding site [chemical binding]; other site
943945000528	substrate binding site [chemical binding]; other site
943945000529	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
943945000530	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945000531	active site
943945000532	HIGH motif; other site
943945000533	nucleotide binding site [chemical binding]; other site
943945000534	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
943945000535	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
943945000536	active site
943945000537	KMSKS motif; other site
943945000538	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
943945000539	tRNA binding surface [nucleotide binding]; other site
943945000540	anticodon binding site; other site
943945000541	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
943945000542	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
943945000543	OB-fold nucleic acid binding domain; Region: tRNA_anti_2; pfam13742
943945000544	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
943945000545	generic binding surface I; other site
943945000546	Exonuclease VII small subunit; Region: Exonuc_VII_S; cl00750
943945000547	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
943945000548	Part of AAA domain; Region: AAA_19; pfam13245
943945000549	AAA domain; Region: AAA_12; pfam13087
943945000550	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
943945000551	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
943945000552	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
943945000553	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
943945000554	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945000555	dimer interface [polypeptide binding]; other site
943945000556	conserved gate region; other site
943945000557	putative PBP binding loops; other site
943945000558	ABC-ATPase subunit interface; other site
943945000559	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
943945000560	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945000561	dimer interface [polypeptide binding]; other site
943945000562	conserved gate region; other site
943945000563	putative PBP binding loops; other site
943945000564	ABC-ATPase subunit interface; other site
943945000565	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
943945000566	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
943945000567	Walker A/P-loop; other site
943945000568	ATP binding site [chemical binding]; other site
943945000569	Q-loop/lid; other site
943945000570	ABC transporter signature motif; other site
943945000571	Walker B; other site
943945000572	D-loop; other site
943945000573	H-loop/switch region; other site
943945000574	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
943945000575	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000576	AAA domain; Region: AAA_21; pfam13304
943945000577	Walker A/P-loop; other site
943945000578	ATP binding site [chemical binding]; other site
943945000579	Q-loop/lid; other site
943945000580	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
943945000581	ABC transporter signature motif; other site
943945000582	Walker B; other site
943945000583	D-loop; other site
943945000584	H-loop/switch region; other site
943945000585	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
943945000586	asparagine synthetase AsnA; Provisional; Region: PRK05425
943945000587	motif 1; other site
943945000588	dimer interface [polypeptide binding]; other site
943945000589	active site
943945000590	motif 2; other site
943945000591	motif 3; other site
943945000592	Uncharacterized conserved protein [Function unknown]; Region: COG4095
943945000593	PQ loop repeat; Region: PQ-loop; pfam04193
943945000594	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
943945000595	putative active site pocket [active]
943945000596	dimerization interface [polypeptide binding]; other site
943945000597	putative catalytic residue [active]
943945000598	DNA protecting protein DprA; Region: dprA; TIGR00732
943945000599	RuvA N terminal domain; Region: RuvA_N; pfam01330
943945000600	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
943945000601	helix-hairpin-helix signature motif; other site
943945000602	active site
943945000603	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
943945000604	recombination factor protein RarA; Reviewed; Region: PRK13342
943945000605	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
943945000606	DNA methylase; Region: N6_N4_Mtase; cl17433
943945000607	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945000608	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945000609	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945000610	potential frameshift: common BLAST hit: gi|308189853|ref|YP_003922784.1| trsE-like protein
943945000611	AAA-like domain; Region: AAA_10; pfam12846
943945000612	Domain of unknown function DUF87; Region: DUF87; pfam01935
943945000613	Zonular occludens toxin (Zot); Region: Zot; cl17485
943945000614	Homeodomain-like domain; Region: HTH_23; pfam13384
943945000615	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
943945000616	B3/4 domain; Region: B3_4; pfam03483
943945000617	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
943945000618	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
943945000619	enolase; Provisional; Region: eno; PRK00077
943945000620	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
943945000621	dimer interface [polypeptide binding]; other site
943945000622	metal binding site [ion binding]; metal-binding site
943945000623	substrate binding pocket [chemical binding]; other site
943945000624	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
943945000625	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
943945000626	active site
943945000627	metal binding site [ion binding]; metal-binding site
943945000628	substrate binding site [chemical binding]; other site
943945000629	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
943945000630	elongation factor Tu; Reviewed; Region: PRK00049
943945000631	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
943945000632	G1 box; other site
943945000633	GEF interaction site [polypeptide binding]; other site
943945000634	GTP/Mg2+ binding site [chemical binding]; other site
943945000635	Switch I region; other site
943945000636	G2 box; other site
943945000637	G3 box; other site
943945000638	Switch II region; other site
943945000639	G4 box; other site
943945000640	G5 box; other site
943945000641	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
943945000642	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
943945000643	Antibiotic Binding Site [chemical binding]; other site
943945000644	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
943945000645	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
943945000646	UGMP family protein; Validated; Region: PRK09604
943945000647	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
943945000648	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; cl01839
943945000649	Predicted acetyltransferase [General function prediction only]; Region: COG3393
943945000650	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
943945000651	signal recognition particle protein; Provisional; Region: PRK10867
943945000652	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
943945000653	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
943945000654	P loop; other site
943945000655	GTP binding site [chemical binding]; other site
943945000656	Signal peptide binding domain; Region: SRP_SPB; pfam02978
943945000657	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; pfam09529
943945000658	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
943945000659	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
943945000660	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
943945000661	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
943945000662	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
943945000663	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
943945000664	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
943945000665	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
943945000666	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
943945000667	beta subunit interaction interface [polypeptide binding]; other site
943945000668	Walker A motif; other site
943945000669	ATP binding site [chemical binding]; other site
943945000670	Walker B motif; other site
943945000671	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
943945000672	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
943945000673	core domain interface [polypeptide binding]; other site
943945000674	delta subunit interface [polypeptide binding]; other site
943945000675	epsilon subunit interface [polypeptide binding]; other site
943945000676	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
943945000677	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
943945000678	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
943945000679	alpha subunit interaction interface [polypeptide binding]; other site
943945000680	Walker A motif; other site
943945000681	ATP binding site [chemical binding]; other site
943945000682	Walker B motif; other site
943945000683	inhibitor binding site; inhibition site
943945000684	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
943945000685	F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) [Energy production and conversion]; Region: AtpC; COG0355
943945000686	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
943945000687	gamma subunit interface [polypeptide binding]; other site
943945000688	epsilon subunit interface [polypeptide binding]; other site
943945000689	LBP interface [polypeptide binding]; other site
943945000690	Smr domain; Region: Smr; pfam01713
943945000691	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
943945000692	active site turn [active]
943945000693	phosphorylation site [posttranslational modification]
943945000694	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
943945000695	HPr interaction site; other site
943945000696	glycerol kinase (GK) interaction site [polypeptide binding]; other site
943945000697	active site
943945000698	phosphorylation site [posttranslational modification]
943945000699	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
943945000700	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
943945000701	putative ligand binding site [chemical binding]; other site
943945000702	putative NAD binding site [chemical binding]; other site
943945000703	catalytic site [active]
943945000704	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
943945000705	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945000706	dimer interface [polypeptide binding]; other site
943945000707	conserved gate region; other site
943945000708	ABC-ATPase subunit interface; other site
943945000709	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
943945000710	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
943945000711	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945000712	dimer interface [polypeptide binding]; other site
943945000713	conserved gate region; other site
943945000714	putative PBP binding loops; other site
943945000715	ABC-ATPase subunit interface; other site
943945000716	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
943945000717	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
943945000718	Walker A/P-loop; other site
943945000719	ATP binding site [chemical binding]; other site
943945000720	Q-loop/lid; other site
943945000721	ABC transporter signature motif; other site
943945000722	Walker B; other site
943945000723	D-loop; other site
943945000724	H-loop/switch region; other site
943945000725	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
943945000726	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
943945000727	Walker A/P-loop; other site
943945000728	ATP binding site [chemical binding]; other site
943945000729	Q-loop/lid; other site
943945000730	AAA domain; Region: AAA_21; pfam13304
943945000731	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
943945000732	ABC transporter signature motif; other site
943945000733	Walker B; other site
943945000734	D-loop; other site
943945000735	H-loop/switch region; other site
943945000736	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
943945000737	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
943945000738	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
943945000739	interface (dimer of trimers) [polypeptide binding]; other site
943945000740	Substrate-binding/catalytic site; other site
943945000741	Zn-binding sites [ion binding]; other site
943945000742	AAA domain; Region: AAA_14; pfam13173
943945000743	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945000744	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945000745	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
943945000746	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
943945000747	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
943945000748	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
943945000749	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
943945000750	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
943945000751	phosphoglyceromutase; Provisional; Region: PRK05434
943945000752	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
943945000753	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
943945000754	active site
943945000755	motif I; other site
943945000756	motif II; other site
943945000757	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
943945000758	Topoisomerase II-associated protein PAT1; Region: PAT1; pfam09770
943945000759	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
943945000760	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
943945000761	nucleotide binding region [chemical binding]; other site
943945000762	helicase superfamily c-terminal domain; Region: HELICc; smart00490
943945000763	ATP-binding site [chemical binding]; other site
943945000764	Uncharacterized conserved protein [Function unknown]; Region: COG1284
943945000765	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
943945000766	Uncharacterized conserved protein [Function unknown]; Region: COG1284
943945000767	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
943945000768	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
943945000769	Endonuclease I; Region: Endonuclease_1; cl01003
943945000770	excinuclease ABC subunit B; Provisional; Region: PRK05298
943945000771	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
943945000772	ATP binding site [chemical binding]; other site
943945000773	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
943945000774	nucleotide binding region [chemical binding]; other site
943945000775	ATP-binding site [chemical binding]; other site
943945000776	Ultra-violet resistance protein B; Region: UvrB; pfam12344
943945000777	UvrB/uvrC motif; Region: UVR; pfam02151
943945000778	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
943945000779	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
943945000780	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
943945000781	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
943945000782	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
943945000783	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
943945000784	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
943945000785	RPB1 interaction site [polypeptide binding]; other site
943945000786	RPB10 interaction site [polypeptide binding]; other site
943945000787	RPB11 interaction site [polypeptide binding]; other site
943945000788	RPB3 interaction site [polypeptide binding]; other site
943945000789	RPB12 interaction site [polypeptide binding]; other site
943945000790	DNA-directed RNA polymerase subunit gamma; Provisional; Region: rpoC1; PRK02625
943945000791	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
943945000792	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
943945000793	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
943945000794	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
943945000795	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
943945000796	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
943945000797	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
943945000798	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
943945000799	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
943945000800	DNA binding site [nucleotide binding]
943945000801	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
943945000802	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
943945000803	active site
943945000804	catalytic triad [active]
943945000805	oxyanion hole [active]
943945000806	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
943945000807	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
943945000808	oligomer interface [polypeptide binding]; other site
943945000809	active site
943945000810	metal binding site [ion binding]; metal-binding site
943945000811	hypothetical protein; Provisional; Region: PRK00523
943945000812	DNA topoisomerase I; Validated; Region: PRK05582
943945000813	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
943945000814	active site
943945000815	metal binding site [ion binding]; metal-binding site
943945000816	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
943945000817	domain I; other site
943945000818	DNA binding groove [nucleotide binding]
943945000819	phosphate binding site [ion binding]; other site
943945000820	domain II; other site
943945000821	domain III; other site
943945000822	nucleotide binding site [chemical binding]; other site
943945000823	catalytic site [active]
943945000824	domain IV; other site
943945000825	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
943945000826	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
943945000827	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
943945000828	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
943945000829	dimer interface [polypeptide binding]; other site
943945000830	ssDNA binding site [nucleotide binding]; other site
943945000831	tetramer (dimer of dimers) interface [polypeptide binding]; other site
943945000832	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
943945000833	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
943945000834	trigger factor; Region: tig; TIGR00115
943945000835	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
943945000836	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000837	Walker A/P-loop; other site
943945000838	ATP binding site [chemical binding]; other site
943945000839	Q-loop/lid; other site
943945000840	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
943945000841	ABC transporter; Region: ABC_tran_2; pfam12848
943945000842	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000843	Walker A/P-loop; other site
943945000844	ATP binding site [chemical binding]; other site
943945000845	Q-loop/lid; other site
943945000846	ABC transporter signature motif; other site
943945000847	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
943945000848	Walker B; other site
943945000849	D-loop; other site
943945000850	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
943945000851	RuvA N terminal domain; Region: RuvA_N; pfam01330
943945000852	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
943945000853	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
943945000854	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945000855	Walker A motif; other site
943945000856	ATP binding site [chemical binding]; other site
943945000857	Walker B motif; other site
943945000858	arginine finger; other site
943945000859	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
943945000860	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
943945000861	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
943945000862	Protein export membrane protein; Region: SecD_SecF; cl14618
943945000863	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02193
943945000864	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
943945000865	RNA binding site [nucleotide binding]; other site
943945000866	active site
943945000867	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
943945000868	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
943945000869	active site
943945000870	motif I; other site
943945000871	motif II; other site
943945000872	hypothetical protein; Provisional; Region: PRK07143
943945000873	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945000874	active site
943945000875	nucleotide binding site [chemical binding]; other site
943945000876	HIGH motif; other site
943945000877	KMSKS motif; other site
943945000878	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
943945000879	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000880	Walker A/P-loop; other site
943945000881	ATP binding site [chemical binding]; other site
943945000882	Q-loop/lid; other site
943945000883	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
943945000884	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
943945000885	ABC transporter signature motif; other site
943945000886	Walker B; other site
943945000887	D-loop; other site
943945000888	H-loop/switch region; other site
943945000889	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
943945000890	Mycoplasma MG185/MG260 protein; Region: Lipoprotein_X; pfam03305
943945000891	Putative mycoplasma lipoprotein, C-terminal region; Region: Lipoprotein_10; pfam03202
943945000892	Micrococcal nuclease (thermonuclease) homologs [DNA replication, recombination, and repair]; Region: COG1525
943945000893	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140
943945000894	Catalytic site; other site
943945000895	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
943945000896	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000897	Walker A/P-loop; other site
943945000898	ATP binding site [chemical binding]; other site
943945000899	Q-loop/lid; other site
943945000900	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
943945000901	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945000902	ABC transporter signature motif; other site
943945000903	Walker B; other site
943945000904	D-loop; other site
943945000905	H-loop/switch region; other site
943945000906	TOBE domain; Region: TOBE_2; pfam08402
943945000907	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945000908	dimer interface [polypeptide binding]; other site
943945000909	conserved gate region; other site
943945000910	putative PBP binding loops; other site
943945000911	ABC-ATPase subunit interface; other site
943945000912	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
943945000913	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945000914	dimer interface [polypeptide binding]; other site
943945000915	conserved gate region; other site
943945000916	putative PBP binding loops; other site
943945000917	ABC-ATPase subunit interface; other site
943945000918	RmuC family; Region: RmuC; pfam02646
943945000919	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
943945000920	Coenzyme A binding pocket [chemical binding]; other site
943945000921	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
943945000922	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
943945000923	conserved cys residue [active]
943945000924	DNA gyrase subunit A; Validated; Region: PRK05560
943945000925	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
943945000926	CAP-like domain; other site
943945000927	active site
943945000928	primary dimer interface [polypeptide binding]; other site
943945000929	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
943945000930	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
943945000931	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
943945000932	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
943945000933	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
943945000934	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
943945000935	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
943945000936	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
943945000937	RNA binding surface [nucleotide binding]; other site
943945000938	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
943945000939	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
943945000940	GrpE; Region: GrpE; pfam01025
943945000941	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
943945000942	dimer interface [polypeptide binding]; other site
943945000943	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
943945000944	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
943945000945	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
943945000946	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
943945000947	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
943945000948	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
943945000949	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
943945000950	23S rRNA binding site [nucleotide binding]; other site
943945000951	L21 binding site [polypeptide binding]; other site
943945000952	L13 binding site [polypeptide binding]; other site
943945000953	Transposase, Mutator family; Region: Transposase_mut; pfam00872
943945000954	MULE transposase domain; Region: MULE; pfam10551
943945000955	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
943945000956	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
943945000957	active site
943945000958	catalytic residues [active]
943945000959	DNA binding site [nucleotide binding]
943945000960	Int/Topo IB signature motif; other site
943945000961	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12903
943945000962	V-type ATP synthase subunit I; Validated; Region: PRK05771
943945000963	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
943945000964	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
943945000965	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
943945000966	beta-amylase; Region: PLN02705
943945000967	AAA-like domain; Region: AAA_10; pfam12846
943945000968	Domain of unknown function DUF87; Region: DUF87; pfam01935
943945000969	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
943945000970	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
943945000971	dimer interface [polypeptide binding]; other site
943945000972	ssDNA binding site [nucleotide binding]; other site
943945000973	tetramer (dimer of dimers) interface [polypeptide binding]; other site
943945000974	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
943945000975	potential frameshift: common BLAST hit: gi|313678309|ref|YP_004056049.1| TraG/TraD family protein (ICEB-2 encoded)
943945000976	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
943945000977	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
943945000978	Walker A motif; other site
943945000979	ATP binding site [chemical binding]; other site
943945000980	Mitochondrial inner membrane protein; Region: Mitofilin; pfam09731
943945000981	GTP-binding protein LepA; Provisional; Region: PRK05433
943945000982	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
943945000983	G1 box; other site
943945000984	putative GEF interaction site [polypeptide binding]; other site
943945000985	GTP/Mg2+ binding site [chemical binding]; other site
943945000986	Switch I region; other site
943945000987	G2 box; other site
943945000988	G3 box; other site
943945000989	Switch II region; other site
943945000990	G4 box; other site
943945000991	G5 box; other site
943945000992	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
943945000993	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
943945000994	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
943945000995	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
943945000996	active site
943945000997	substrate binding site [chemical binding]; other site
943945000998	ATP binding site [chemical binding]; other site
943945000999	Phosphotransferase enzyme family; Region: APH; pfam01636
943945001000	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
943945001001	Part of AAA domain; Region: AAA_19; pfam13245
943945001002	AAA domain; Region: AAA_12; pfam13087
943945001003	reticulocyte binding/rhoptry protein; Region: 235kDa-fam; TIGR01612
943945001004	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
943945001005	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
943945001006	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
943945001007	active site
943945001008	Predicted membrane protein [Function unknown]; Region: COG3601
943945001009	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
943945001010	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
943945001011	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
943945001012	HIGH motif; other site
943945001013	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
943945001014	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945001015	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945001016	active site
943945001017	KMSKS motif; other site
943945001018	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
943945001019	tRNA binding surface [nucleotide binding]; other site
943945001020	anticodon binding site; other site
943945001021	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945001022	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
943945001023	Walker A motif; other site
943945001024	ATP binding site [chemical binding]; other site
943945001025	Walker B motif; other site
943945001026	arginine finger; other site
943945001027	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
943945001028	SdpI/YhfL protein family; Region: SdpI; pfam13630
943945001029	dUTPase; Region: dUTPase_2; pfam08761
943945001030	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527
943945001031	active site
943945001032	homodimer interface [polypeptide binding]; other site
943945001033	metal binding site [ion binding]; metal-binding site
943945001034	Uncharacterized conserved protein [Function unknown]; Region: COG0327
943945001035	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
943945001036	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
943945001037	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
943945001038	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
943945001039	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
943945001040	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
943945001041	DNA binding residues [nucleotide binding]
943945001042	DNA primase, catalytic core; Region: dnaG; TIGR01391
943945001043	CHC2 zinc finger; Region: zf-CHC2; cl17510
943945001044	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
943945001045	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
943945001046	active site
943945001047	metal binding site [ion binding]; metal-binding site
943945001048	interdomain interaction site; other site
943945001049	glycyl-tRNA synthetase; Provisional; Region: PRK04173
943945001050	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
943945001051	motif 1; other site
943945001052	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
943945001053	active site
943945001054	motif 2; other site
943945001055	motif 3; other site
943945001056	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
943945001057	anticodon binding site; other site
943945001058	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
943945001059	RNA binding site [nucleotide binding]; other site
943945001060	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
943945001061	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
943945001062	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
943945001063	active site
943945001064	dimer interface [polypeptide binding]; other site
943945001065	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
943945001066	dimer interface [polypeptide binding]; other site
943945001067	active site
943945001068	AAA domain; Region: AAA_14; pfam13173
943945001069	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945001070	potential frameshift: common BLAST hit: gi|308190214|ref|YP_003923145.1| transposase for IS1630-like insertion sequence element
943945001071	potential frameshift: common BLAST hit: gi|308190214|ref|YP_003923145.1| transposase for IS1630-like insertion sequence element
943945001072	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
943945001073	Integrase core domain; Region: rve; pfam00665
943945001074	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
943945001075	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
943945001076	DNA binding site [nucleotide binding]
943945001077	catalytic residue [active]
943945001078	H2TH interface [polypeptide binding]; other site
943945001079	putative catalytic residues [active]
943945001080	turnover-facilitating residue; other site
943945001081	intercalation triad [nucleotide binding]; other site
943945001082	8OG recognition residue [nucleotide binding]; other site
943945001083	putative reading head residues; other site
943945001084	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
943945001085	AAA domain; Region: AAA_14; pfam13173
943945001086	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945001087	membrane protein; Provisional; Region: PRK14418
943945001088	High affinity transport system protein p37; Region: Mycoplasma_p37; pfam06646
943945001089	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945001090	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
943945001091	Walker A/P-loop; other site
943945001092	ATP binding site [chemical binding]; other site
943945001093	Q-loop/lid; other site
943945001094	ABC transporter signature motif; other site
943945001095	Walker B; other site
943945001096	D-loop; other site
943945001097	H-loop/switch region; other site
943945001098	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
943945001099	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12903
943945001100	Transposase, Mutator family; Region: Transposase_mut; pfam00872
943945001101	MULE transposase domain; Region: MULE; pfam10551
943945001102	Transposase, Mutator family; Region: Transposase_mut; pfam00872
943945001103	Transposase, Mutator family; Region: Transposase_mut; pfam00872
943945001104	MULE transposase domain; Region: MULE; pfam10551
943945001105	AAA-like domain; Region: AAA_10; pfam12846
943945001106	Domain of unknown function DUF87; Region: DUF87; pfam01935
943945001107	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
943945001108	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
943945001109	dimer interface [polypeptide binding]; other site
943945001110	ssDNA binding site [nucleotide binding]; other site
943945001111	tetramer (dimer of dimers) interface [polypeptide binding]; other site
943945001112	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
943945001113	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
943945001114	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
943945001115	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
943945001116	Mitochondrial inner membrane protein; Region: Mitofilin; pfam09731
943945001117	Homeodomain-like domain; Region: HTH_23; pfam13384
943945001118	AAA-like domain; Region: AAA_10; pfam12846
943945001119	Domain of unknown function DUF87; Region: DUF87; pfam01935
943945001120	Zonular occludens toxin (Zot); Region: Zot; cl17485
943945001121	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945001122	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945001123	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
943945001124	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
943945001125	DNA methylase; Region: N6_N4_Mtase; cl17433
943945001126	recombination factor protein RarA; Reviewed; Region: PRK13342
943945001127	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
943945001128	RuvA N terminal domain; Region: RuvA_N; pfam01330
943945001129	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
943945001130	helix-hairpin-helix signature motif; other site
943945001131	active site
943945001132	DNA protecting protein DprA; Region: dprA; TIGR00732
943945001133	NAD-dependent DNA ligase (contains BRCT domain type II) [DNA replication, recombination, and repair]; Region: Lig; COG0272
943945001134	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
943945001135	nucleotide binding pocket [chemical binding]; other site
943945001136	K-X-D-G motif; other site
943945001137	catalytic site [active]
943945001138	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
943945001139	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
943945001140	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
943945001141	Dimer interface [polypeptide binding]; other site
943945001142	BRCT sequence motif; other site
943945001143	triosephosphate isomerase; Provisional; Region: PRK14565
943945001144	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
943945001145	substrate binding site [chemical binding]; other site
943945001146	dimer interface [polypeptide binding]; other site
943945001147	catalytic triad [active]
943945001148	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
943945001149	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
943945001150	active site
943945001151	trimer interface [polypeptide binding]; other site
943945001152	allosteric site; other site
943945001153	active site lid [active]
943945001154	hexamer (dimer of trimers) interface [polypeptide binding]; other site
943945001155	Amidohydrolase; Region: Amidohydro_4; pfam13147
943945001156	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
943945001157	active site
943945001158	Phosphoglycerate kinase; Region: PGK; pfam00162
943945001159	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
943945001160	substrate binding site [chemical binding]; other site
943945001161	hinge regions; other site
943945001162	ADP binding site [chemical binding]; other site
943945001163	catalytic site [active]
943945001164	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
943945001165	active site turn [active]
943945001166	phosphorylation site [posttranslational modification]
943945001167	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
943945001168	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
943945001169	active site
943945001170	HIGH motif; other site
943945001171	dimer interface [polypeptide binding]; other site
943945001172	KMSKS motif; other site
943945001173	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
943945001174	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
943945001175	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
943945001176	active site
943945001177	dimer interface [polypeptide binding]; other site
943945001178	motif 1; other site
943945001179	motif 2; other site
943945001180	motif 3; other site
943945001181	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
943945001182	anticodon binding site; other site
943945001183	Isochorismatase family; Region: Isochorismatase; pfam00857
943945001184	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
943945001185	catalytic triad [active]
943945001186	conserved cis-peptide bond; other site
943945001187	Smr domain; Region: Smr; pfam01713
943945001188	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
943945001189	intersubunit interface [polypeptide binding]; other site
943945001190	active site
943945001191	catalytic residue [active]
943945001192	Thymidine phosphorylase [Nucleotide transport and metabolism]; Region: DeoA; COG0213
943945001193	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
943945001194	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
943945001195	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
943945001196	Purine-nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: DeoD; COG0813
943945001197	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
943945001198	6-phosphofructokinase; Provisional; Region: PRK03202
943945001199	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
943945001200	active site
943945001201	ADP/pyrophosphate binding site [chemical binding]; other site
943945001202	dimerization interface [polypeptide binding]; other site
943945001203	allosteric effector site; other site
943945001204	fructose-1,6-bisphosphate binding site; other site
943945001205	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
943945001206	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
943945001207	active site
943945001208	motif I; other site
943945001209	motif II; other site
943945001210	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
943945001211	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
943945001212	AAA domain; Region: AAA_14; pfam13173
943945001213	GTPase CgtA; Reviewed; Region: obgE; PRK12297
943945001214	GTP1/OBG; Region: GTP1_OBG; pfam01018
943945001215	Obg GTPase; Region: Obg; cd01898
943945001216	G1 box; other site
943945001217	GTP/Mg2+ binding site [chemical binding]; other site
943945001218	Switch I region; other site
943945001219	G2 box; other site
943945001220	G3 box; other site
943945001221	Switch II region; other site
943945001222	G4 box; other site
943945001223	G5 box; other site
943945001224	Obg family GTPase CgtA, C-terminal extension; Region: Obg_CgtA_exten; TIGR03595
943945001225	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
943945001226	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
943945001227	active site
943945001228	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
943945001229	active site
943945001230	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
943945001231	active site
943945001232	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
943945001233	active site
943945001234	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
943945001235	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
943945001236	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
943945001237	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
943945001238	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
943945001239	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
943945001240	motif 1; other site
943945001241	active site
943945001242	motif 2; other site
943945001243	motif 3; other site
943945001244	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
943945001245	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
943945001246	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
943945001247	Ligand Binding Site [chemical binding]; other site
943945001248	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
943945001249	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
943945001250	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
943945001251	active site
943945001252	HIGH motif; other site
943945001253	KMSK motif region; other site
943945001254	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
943945001255	tRNA binding surface [nucleotide binding]; other site
943945001256	anticodon binding site; other site
943945001257	Amino acid permease; Region: AA_permease_2; pfam13520
943945001258	carbamate kinase; Reviewed; Region: PRK12686
943945001259	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
943945001260	putative substrate binding site [chemical binding]; other site
943945001261	nucleotide binding site [chemical binding]; other site
943945001262	nucleotide binding site [chemical binding]; other site
943945001263	homodimer interface [polypeptide binding]; other site
943945001264	ornithine carbamoyltransferase; Validated; Region: PRK02102
943945001265	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
943945001266	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
943945001267	Amidinotransferase; Region: Amidinotransf; cl12043
943945001268	Domain of unknown function(DUF2779); Region: DUF2779; pfam11074
943945001269	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
943945001270	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
943945001271	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
943945001272	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
943945001273	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
943945001274	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
943945001275	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
943945001276	active site
943945001277	Zn binding site [ion binding]; other site
943945001278	RNA methyltransferase, RsmE family; Region: TIGR00046
943945001279	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
943945001280	cell division protein FtsZ; Validated; Region: PRK09330
943945001281	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
943945001282	nucleotide binding site [chemical binding]; other site
943945001283	SulA interaction site; other site
943945001284	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
943945001285	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
943945001286	S-adenosylmethionine binding site [chemical binding]; other site
943945001287	cell division protein MraZ; Reviewed; Region: PRK00326
943945001288	MraZ protein; Region: MraZ; pfam02381
943945001289	MraZ protein; Region: MraZ; pfam02381
943945001290	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
943945001291	TrkA-N domain; Region: TrkA_N; pfam02254
943945001292	TrkA-C domain; Region: TrkA_C; pfam02080
943945001293	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
943945001294	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
943945001295	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
943945001296	transcriptional regulator MurR; Provisional; Region: PRK15482
943945001297	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
943945001298	putative active site [active]
943945001299	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
943945001300	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
943945001301	putative active site cavity [active]
943945001302	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
943945001303	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
943945001304	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
943945001305	active site turn [active]
943945001306	phosphorylation site [posttranslational modification]
943945001307	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
943945001308	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
943945001309	rRNA interaction site [nucleotide binding]; other site
943945001310	S8 interaction site; other site
943945001311	elongation factor Ts; Provisional; Region: tsf; PRK09377
943945001312	UBA/TS-N domain; Region: UBA; pfam00627
943945001313	Elongation factor TS; Region: EF_TS; pfam00889
943945001314	Elongation factor TS; Region: EF_TS; pfam00889
943945001315	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
943945001316	active site
943945001317	phosphorylation site [posttranslational modification]
943945001318	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DegV; COG1307
943945001319	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
943945001320	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
943945001321	Part of AAA domain; Region: AAA_19; pfam13245
943945001322	Family description; Region: UvrD_C_2; pfam13538
943945001323	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
943945001324	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
943945001325	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
943945001326	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
943945001327	putative dimer interface [polypeptide binding]; other site
943945001328	putative anticodon binding site; other site
943945001329	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
943945001330	motif 1; other site
943945001331	dimer interface [polypeptide binding]; other site
943945001332	active site
943945001333	motif 2; other site
943945001334	motif 3; other site
943945001335	PQ loop repeat; Region: PQ-loop; pfam04193
943945001336	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
943945001337	trimer interface [polypeptide binding]; other site
943945001338	active site
943945001339	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
943945001340	MgtE intracellular N domain; Region: MgtE_N; pfam03448
943945001341	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
943945001342	Divalent cation transporter; Region: MgtE; pfam01769
943945001343	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
943945001344	Divergent AAA domain; Region: AAA_4; pfam04326
943945001345	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
943945001346	potential frameshift: common BLAST hit: gi|308189999|ref|YP_003922930.1| multidrug ABC transporter ATP-binding protein
943945001347	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
943945001348	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
943945001349	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945001350	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
943945001351	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945001352	ABC transporter signature motif; other site
943945001353	Walker B; other site
943945001354	D-loop; other site
943945001355	H-loop/switch region; other site
943945001356	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
943945001357	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
943945001358	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945001359	Walker A/P-loop; other site
943945001360	ATP binding site [chemical binding]; other site
943945001361	Q-loop/lid; other site
943945001362	ABC transporter signature motif; other site
943945001363	Walker B; other site
943945001364	D-loop; other site
943945001365	H-loop/switch region; other site
943945001366	AAA domain; Region: AAA_14; pfam13173
943945001367	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945001368	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
943945001369	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
943945001370	active site
943945001371	motif I; other site
943945001372	motif II; other site
943945001373	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
943945001374	T5orf172 domain; Region: T5orf172; pfam10544
943945001375	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
943945001376	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
943945001377	active site
943945001378	DNA binding site [nucleotide binding]
943945001379	Int/Topo IB signature motif; other site
943945001380	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945001381	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945001382	Target Sequence
943945001383	Mycoplasma phage phiMFV1-1. K. S. Wise and the colleagues have demonstrated the mobility, replication of this prophage and its effect on the mycoplasma surface phenotype. The unique coiled-coil membrane surface protein, Mem, and hypothetical surface lipoproteins expressed from phiMFV1 were considered to associate with the specific, selectable phenotypic traits of the mycoplasma species. [PMID: 15186419]
943945001384	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
943945001385	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
943945001386	Walker A motif; other site
943945001387	ATP binding site [chemical binding]; other site
943945001388	Walker B motif; other site
943945001389	potential frameshift: common BLAST hit: gi|313665615|ref|YP_004047486.1| C-5 cytosine-specific DNA methylase
943945001390	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
943945001391	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
943945001392	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
943945001393	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
943945001394	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
943945001395	active site
943945001396	Int/Topo IB signature motif; other site
943945001397	catalytic residues [active]
943945001398	DNA binding site [nucleotide binding]
943945001399	Predicted endonuclease (RecB family) [DNA replication, recombination, and repair]; Region: COG4998
943945001400	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945001401	Target Sequence
943945001402	HsdM N-terminal domain; Region: HsdM_N; pfam12161
943945001403	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
943945001404	Methyltransferase domain; Region: Methyltransf_26; pfam13659
943945001405	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
943945001406	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
943945001407	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
943945001408	ATP binding site [chemical binding]; other site
943945001409	putative Mg++ binding site [ion binding]; other site
943945001410	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
943945001411	Fic/DOC family; Region: Fic; pfam02661
943945001412	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
943945001413	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
943945001414	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
943945001415	putative active site [active]
943945001416	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
943945001417	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
943945001418	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
943945001419	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
943945001420	active site
943945001421	phosphorylation site [posttranslational modification]
943945001422	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
943945001423	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
943945001424	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
943945001425	active pocket/dimerization site; other site
943945001426	active site
943945001427	phosphorylation site [posttranslational modification]
943945001428	Preprotein translocase subunit; Region: YajC; cl00806
943945001429	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
943945001430	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
943945001431	NADP binding site [chemical binding]; other site
943945001432	homodimer interface [polypeptide binding]; other site
943945001433	active site
943945001434	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
943945001435	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
943945001436	active site
943945001437	intersubunit interface [polypeptide binding]; other site
943945001438	catalytic residue [active]
943945001439	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
943945001440	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
943945001441	substrate binding site [chemical binding]; other site
943945001442	ATP binding site [chemical binding]; other site
943945001443	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
943945001444	substrate binding site [chemical binding]; other site
943945001445	catalytic residues [active]
943945001446	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
943945001447	nicotinate phosphoribosyltransferase; Provisional; Region: PRK07188
943945001448	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
943945001449	active site
943945001450	elongation factor P; Validated; Region: PRK00529
943945001451	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
943945001452	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
943945001453	RNA binding site [nucleotide binding]; other site
943945001454	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
943945001455	RNA binding site [nucleotide binding]; other site
943945001456	LemA family; Region: LemA; cl00742
943945001457	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
943945001458	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
943945001459	putative active site [active]
943945001460	substrate binding site [chemical binding]; other site
943945001461	putative cosubstrate binding site; other site
943945001462	catalytic site [active]
943945001463	Formyl transferase, C-terminal domain; Region: Formyl_trans_C; pfam02911
943945001464	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
943945001465	AAA domain; Region: AAA_23; pfam13476
943945001466	Walker A/P-loop; other site
943945001467	ATP binding site [chemical binding]; other site
943945001468	Q-loop/lid; other site
943945001469	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
943945001470	Nsp1-like C-terminal region; Region: Nsp1_C; pfam05064
943945001471	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
943945001472	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
943945001473	ABC transporter signature motif; other site
943945001474	Walker B; other site
943945001475	D-loop; other site
943945001476	H-loop/switch region; other site
943945001477	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
943945001478	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
943945001479	dimerization interface [polypeptide binding]; other site
943945001480	active site
943945001481	metal binding site [ion binding]; metal-binding site
943945001482	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
943945001483	dsRNA binding site [nucleotide binding]; other site
943945001484	putative phosphate acyltransferase; Provisional; Region: PRK05331
943945001485	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
943945001486	DAK2 domain; Region: Dak2; pfam02734
943945001487	Recombination protein O N terminal; Region: RecO_N; pfam11967
943945001488	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecO; COG1381
943945001489	Recombination protein O C terminal; Region: RecO_C; pfam02565
943945001490	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
943945001491	dimer interface [polypeptide binding]; other site
943945001492	FMN binding site [chemical binding]; other site
943945001493	NADPH bind site [chemical binding]; other site
943945001494	phosphopentomutase; Provisional; Region: PRK05362
943945001495	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
943945001496	Sporulation Regulator WhiA C terminal domain; Region: HTH_WhiA; pfam02650
943945001497	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
943945001498	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
943945001499	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
943945001500	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
943945001501	GTP-binding protein YchF; Reviewed; Region: PRK09601
943945001502	YchF GTPase; Region: YchF; cd01900
943945001503	G1 box; other site
943945001504	GTP/Mg2+ binding site [chemical binding]; other site
943945001505	Switch I region; other site
943945001506	G2 box; other site
943945001507	Switch II region; other site
943945001508	G3 box; other site
943945001509	G4 box; other site
943945001510	G5 box; other site
943945001511	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
943945001512	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
943945001513	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
943945001514	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
943945001515	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
943945001516	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
943945001517	motif II; other site
943945001518	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
943945001519	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
943945001520	putative active site [active]
943945001521	putative catalytic site [active]
943945001522	putative Mg binding site IVb [ion binding]; other site
943945001523	putative phosphate binding site [ion binding]; other site
943945001524	putative DNA binding site [nucleotide binding]; other site
943945001525	putative Mg binding site IVa [ion binding]; other site
943945001526	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
943945001527	active site
943945001528	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
943945001529	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
943945001530	cofactor binding site; other site
943945001531	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
943945001532	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
943945001533	active site
943945001534	motif I; other site
943945001535	motif II; other site
943945001536	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
943945001537	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
943945001538	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
943945001539	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
943945001540	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
943945001541	5S rRNA interface [nucleotide binding]; other site
943945001542	L27 interface [polypeptide binding]; other site
943945001543	23S rRNA interface [nucleotide binding]; other site
943945001544	L5 interface [polypeptide binding]; other site
943945001545	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
943945001546	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
943945001547	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
943945001548	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
943945001549	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
943945001550	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
943945001551	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
943945001552	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
943945001553	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
943945001554	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
943945001555	RNA binding site [nucleotide binding]; other site
943945001556	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
943945001557	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
943945001558	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
943945001559	putative translocon interaction site; other site
943945001560	23S rRNA interface [nucleotide binding]; other site
943945001561	signal recognition particle (SRP54) interaction site; other site
943945001562	L23 interface [polypeptide binding]; other site
943945001563	trigger factor interaction site; other site
943945001564	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
943945001565	23S rRNA interface [nucleotide binding]; other site
943945001566	5S rRNA interface [nucleotide binding]; other site
943945001567	putative antibiotic binding site [chemical binding]; other site
943945001568	L25 interface [polypeptide binding]; other site
943945001569	L27 interface [polypeptide binding]; other site
943945001570	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
943945001571	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
943945001572	G-X-X-G motif; other site
943945001573	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
943945001574	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
943945001575	putative translocon binding site; other site
943945001576	protein-rRNA interface [nucleotide binding]; other site
943945001577	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
943945001578	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
943945001579	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
943945001580	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
943945001581	50S ribosomal protein L23; Reviewed; Region: rplW; PRK12280
943945001582	50S ribosomal protein L4; Provisional; Region: rplD; PRK14907
943945001583	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
943945001584	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
943945001585	recombinase A; Provisional; Region: recA; PRK09354
943945001586	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
943945001587	hexamer interface [polypeptide binding]; other site
943945001588	Walker A motif; other site
943945001589	ATP binding site [chemical binding]; other site
943945001590	Walker B motif; other site
943945001591	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
943945001592	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
943945001593	putative active site [active]
943945001594	metal binding site [ion binding]; metal-binding site
943945001595	homodimer binding site [polypeptide binding]; other site
943945001596	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
943945001597	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
943945001598	oligomer interface [polypeptide binding]; other site
943945001599	active site
943945001600	metal binding site [ion binding]; metal-binding site
943945001601	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
943945001602	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; cl02930
943945001603	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
943945001604	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
943945001605	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
943945001606	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
943945001607	Protein of unknown function DUF45; Region: DUF45; pfam01863
943945001608	Nuclease-related domain; Region: NERD; pfam08378
943945001609	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
943945001610	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
943945001611	transcription antitermination factor NusB; Region: nusB; TIGR01951
943945001612	putative RNA binding site [nucleotide binding]; other site
943945001613	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
943945001614	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
943945001615	HIGH motif; other site
943945001616	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
943945001617	active site
943945001618	KMSKS motif; other site
943945001619	A new structural DNA glycosylase; Region: AlkD_like; cd06561
943945001620	active site
943945001621	potential frameshift: common BLAST hit: gi|308190112|ref|YP_003923043.1| PTS fructose-specific enzyme IIBC component
943945001622	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
943945001623	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
943945001624	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
943945001625	active site
943945001626	phosphorylation site [posttranslational modification]
943945001627	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
943945001628	active site
943945001629	P-loop; other site
943945001630	phosphorylation site [posttranslational modification]
943945001631	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
943945001632	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
943945001633	putative substrate binding site [chemical binding]; other site
943945001634	putative ATP binding site [chemical binding]; other site
943945001635	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
943945001636	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
943945001637	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
943945001638	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
943945001639	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
943945001640	dimer interface [polypeptide binding]; other site
943945001641	anticodon binding site; other site
943945001642	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
943945001643	motif 1; other site
943945001644	dimer interface [polypeptide binding]; other site
943945001645	active site
943945001646	motif 2; other site
943945001647	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
943945001648	active site
943945001649	motif 3; other site
943945001650	histidyl-tRNA synthetase; Region: hisS; TIGR00442
943945001651	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
943945001652	dimer interface [polypeptide binding]; other site
943945001653	motif 1; other site
943945001654	active site
943945001655	motif 2; other site
943945001656	motif 3; other site
943945001657	Amino acid permease; Region: AA_permease_2; pfam13520
943945001658	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945001659	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
943945001660	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945001661	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
943945001662	Divergent AAA domain; Region: AAA_4; pfam04326
943945001663	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
943945001664	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
943945001665	dimerization interface [polypeptide binding]; other site
943945001666	putative DNA binding site [nucleotide binding]; other site
943945001667	putative Zn2+ binding site [ion binding]; other site
943945001668	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
943945001669	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
943945001670	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
943945001671	Walker A/P-loop; other site
943945001672	ATP binding site [chemical binding]; other site
943945001673	Q-loop/lid; other site
943945001674	ABC transporter signature motif; other site
943945001675	Walker B; other site
943945001676	D-loop; other site
943945001677	H-loop/switch region; other site
943945001678	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
943945001679	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
943945001680	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945001681	Walker A/P-loop; other site
943945001682	ATP binding site [chemical binding]; other site
943945001683	Q-loop/lid; other site
943945001684	ABC transporter signature motif; other site
943945001685	Walker B; other site
943945001686	D-loop; other site
943945001687	H-loop/switch region; other site
943945001688	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
943945001689	nudix motif; other site
943945001690	beta-phosphoglucomutase; Region: bPGM; TIGR01990
943945001691	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
943945001692	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
943945001693	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
943945001694	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
943945001695	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
943945001696	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
943945001697	active site
943945001698	catalytic site [active]
943945001699	pullulanase, type I; Region: pulA_typeI; TIGR02104
943945001700	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
943945001701	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
943945001702	Ca binding site [ion binding]; other site
943945001703	active site
943945001704	catalytic site [active]
943945001705	Archaeal/eukaryotic core primase: Large subunit, PriL; Region: PriL; cl11970
943945001706	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
943945001707	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
943945001708	DNA-binding site [nucleotide binding]; DNA binding site
943945001709	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
943945001710	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac2_AmyA; cd11316
943945001711	Ca binding site [ion binding]; other site
943945001712	active site
943945001713	catalytic site [active]
943945001714	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
943945001715	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
943945001716	Walker A/P-loop; other site
943945001717	ATP binding site [chemical binding]; other site
943945001718	Q-loop/lid; other site
943945001719	ABC transporter signature motif; other site
943945001720	Walker B; other site
943945001721	D-loop; other site
943945001722	H-loop/switch region; other site
943945001723	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
943945001724	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945001725	dimer interface [polypeptide binding]; other site
943945001726	conserved gate region; other site
943945001727	putative PBP binding loops; other site
943945001728	ABC-ATPase subunit interface; other site
943945001729	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
943945001730	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945001731	dimer interface [polypeptide binding]; other site
943945001732	conserved gate region; other site
943945001733	putative PBP binding loops; other site
943945001734	ABC-ATPase subunit interface; other site
943945001735	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
943945001736	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
943945001737	active site
943945001738	catalytic site [active]
943945001739	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
943945001740	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
943945001741	active site
943945001742	substrate binding site [chemical binding]; other site
943945001743	metal binding site [ion binding]; metal-binding site
943945001744	Uncharacterized conserved protein [Function unknown]; Region: COG1284
943945001745	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
943945001746	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
943945001747	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
943945001748	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
943945001749	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
943945001750	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
943945001751	NAD binding site [chemical binding]; other site
943945001752	substrate binding site [chemical binding]; other site
943945001753	catalytic Zn binding site [ion binding]; other site
943945001754	tetramer interface [polypeptide binding]; other site
943945001755	structural Zn binding site [ion binding]; other site
943945001756	DNA protecting protein DprA; Region: dprA; TIGR00732
943945001757	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
943945001758	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
943945001759	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
943945001760	active site
943945001761	motif I; other site
943945001762	motif II; other site
943945001763	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
943945001764	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
943945001765	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13651
943945001766	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
943945001767	Walker A/P-loop; other site
943945001768	ATP binding site [chemical binding]; other site
943945001769	Q-loop/lid; other site
943945001770	ABC transporter signature motif; other site
943945001771	Walker B; other site
943945001772	D-loop; other site
943945001773	H-loop/switch region; other site
943945001774	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13632
943945001775	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
943945001776	Walker A/P-loop; other site
943945001777	ATP binding site [chemical binding]; other site
943945001778	Q-loop/lid; other site
943945001779	ABC transporter signature motif; other site
943945001780	Walker B; other site
943945001781	D-loop; other site
943945001782	H-loop/switch region; other site
943945001783	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
943945001784	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
943945001785	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
943945001786	alphaNTD homodimer interface [polypeptide binding]; other site
943945001787	alphaNTD - beta interaction site [polypeptide binding]; other site
943945001788	alphaNTD - beta' interaction site [polypeptide binding]; other site
943945001789	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
943945001790	30S ribosomal protein S11; Validated; Region: PRK05309
943945001791	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
943945001792	30S ribosomal protein S13; Region: bact_S13; TIGR03631
943945001793	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
943945001794	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
943945001795	rRNA binding site [nucleotide binding]; other site
943945001796	predicted 30S ribosome binding site; other site
943945001797	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
943945001798	active site
943945001799	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
943945001800	adenylate kinase; Reviewed; Region: adk; PRK00279
943945001801	AMP-binding site [chemical binding]; other site
943945001802	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
943945001803	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
943945001804	SecY translocase; Region: SecY; pfam00344
943945001805	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
943945001806	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
943945001807	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
943945001808	Ligand Binding Site [chemical binding]; other site
943945001809	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
943945001810	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945001811	dimer interface [polypeptide binding]; other site
943945001812	conserved gate region; other site
943945001813	ABC-ATPase subunit interface; other site
943945001814	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
943945001815	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945001816	dimer interface [polypeptide binding]; other site
943945001817	conserved gate region; other site
943945001818	putative PBP binding loops; other site
943945001819	ABC-ATPase subunit interface; other site
943945001820	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
943945001821	dimerization domain swap beta strand [polypeptide binding]; other site
943945001822	regulatory protein interface [polypeptide binding]; other site
943945001823	active site
943945001824	regulatory phosphorylation site [posttranslational modification]; other site
943945001825	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
943945001826	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
943945001827	Walker A/P-loop; other site
943945001828	ATP binding site [chemical binding]; other site
943945001829	Q-loop/lid; other site
943945001830	ABC transporter signature motif; other site
943945001831	Walker B; other site
943945001832	D-loop; other site
943945001833	H-loop/switch region; other site
943945001834	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
943945001835	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
943945001836	16S/18S rRNA binding site [nucleotide binding]; other site
943945001837	S13e-L30e interaction site [polypeptide binding]; other site
943945001838	25S rRNA binding site [nucleotide binding]; other site
943945001839	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
943945001840	S17 interaction site [polypeptide binding]; other site
943945001841	S8 interaction site; other site
943945001842	16S rRNA interaction site [nucleotide binding]; other site
943945001843	streptomycin interaction site [chemical binding]; other site
943945001844	23S rRNA interaction site [nucleotide binding]; other site
943945001845	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
943945001846	30S ribosomal protein S7; Validated; Region: PRK05302
943945001847	elongation factor G; Reviewed; Region: PRK12739
943945001848	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
943945001849	G1 box; other site
943945001850	putative GEF interaction site [polypeptide binding]; other site
943945001851	GTP/Mg2+ binding site [chemical binding]; other site
943945001852	Switch I region; other site
943945001853	G2 box; other site
943945001854	G3 box; other site
943945001855	Switch II region; other site
943945001856	G4 box; other site
943945001857	G5 box; other site
943945001858	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
943945001859	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
943945001860	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
943945001861	AAA domain; Region: AAA_14; pfam13173
943945001862	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945001863	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
943945001864	S-adenosylmethionine synthetase; Validated; Region: PRK05250
943945001865	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
943945001866	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
943945001867	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
943945001868	core dimer interface [polypeptide binding]; other site
943945001869	peripheral dimer interface [polypeptide binding]; other site
943945001870	L10 interface [polypeptide binding]; other site
943945001871	L11 interface [polypeptide binding]; other site
943945001872	putative EF-Tu interaction site [polypeptide binding]; other site
943945001873	putative EF-G interaction site [polypeptide binding]; other site
943945001874	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
943945001875	23S rRNA interface [nucleotide binding]; other site
943945001876	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
943945001877	Domain of unknown function DUF21; Region: DUF21; pfam01595
943945001878	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
943945001879	replicative DNA helicase; Region: DnaB; TIGR00665
943945001880	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
943945001881	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
943945001882	Walker A motif; other site
943945001883	ATP binding site [chemical binding]; other site
943945001884	Walker B motif; other site
943945001885	DNA binding loops [nucleotide binding]
943945001886	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
943945001887	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
943945001888	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
943945001889	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
943945001890	DHH family; Region: DHH; pfam01368
943945001891	HTH-like domain; Region: HTH_21; pfam13276
943945001892	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
943945001893	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
943945001894	active site
943945001895	motif I; other site
943945001896	motif II; other site
943945001897	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
943945001898	endonuclease IV; Provisional; Region: PRK01060
943945001899	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
943945001900	AP (apurinic/apyrimidinic) site pocket; other site
943945001901	DNA interaction; other site
943945001902	Metal-binding active site; metal-binding site
943945001903	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
943945001904	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
943945001905	catalytic residues [active]
943945001906	Nuclease subunit of the excinuclease complex [DNA replication, recombination, and repair]; Region: UvrC; COG0322
943945001907	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
943945001908	GIY-YIG motif/motif A; other site
943945001909	active site
943945001910	catalytic site [active]
943945001911	putative DNA binding site [nucleotide binding]; other site
943945001912	metal binding site [ion binding]; metal-binding site
943945001913	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
943945001914	AAA domain; Region: AAA_14; pfam13173
943945001915	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945001916	Fic family protein [Function unknown]; Region: COG3177
943945001917	Fic/DOC family; Region: Fic; pfam02661
943945001918	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
943945001919	Divergent AAA domain; Region: AAA_4; pfam04326
943945001920	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
943945001921	Mitochondrial inner membrane protein; Region: Mitofilin; pfam09731
943945001922	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
943945001923	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
943945001924	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
943945001925	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
943945001926	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
943945001927	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
943945001928	dimer interface [polypeptide binding]; other site
943945001929	ssDNA binding site [nucleotide binding]; other site
943945001930	tetramer (dimer of dimers) interface [polypeptide binding]; other site
943945001931	AAA-like domain; Region: AAA_10; pfam12846
943945001932	Domain of unknown function DUF87; Region: DUF87; pfam01935
943945001933	Fic family protein [Function unknown]; Region: COG3177
943945001934	Fic/DOC family; Region: Fic; pfam02661
943945001935	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
943945001936	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
943945001937	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
943945001938	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
943945001939	RNA binding site [nucleotide binding]; other site
943945001940	CTP synthetase; Validated; Region: pyrG; PRK05380
943945001941	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
943945001942	Catalytic site [active]
943945001943	active site
943945001944	UTP binding site [chemical binding]; other site
943945001945	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
943945001946	active site
943945001947	putative oxyanion hole; other site
943945001948	catalytic triad [active]
943945001949	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
943945001950	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945001951	active site
943945001952	HIGH motif; other site
943945001953	nucleotide binding site [chemical binding]; other site
943945001954	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
943945001955	active site
943945001956	KMSKS motif; other site
943945001957	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
943945001958	tRNA binding surface [nucleotide binding]; other site
943945001959	anticodon binding site; other site
943945001960	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
943945001961	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
943945001962	Divergent AAA domain; Region: AAA_4; pfam04326
943945001963	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
943945001964	HTH domain; Region: HTH_11; pfam08279
943945001965	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
943945001966	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria and archaea; Region: GIY-YIG_unchar_2; cd10447
943945001967	GIY-YIG motif/motif A; other site
943945001968	putative active site [active]
943945001969	putative metal binding site [ion binding]; other site
943945001970	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
943945001971	gating phenylalanine in ion channel; other site
943945001972	Protein of unknown function DUF262; Region: DUF262; pfam03235
943945001973	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
943945001974	cofactor binding site; other site
943945001975	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
943945001976	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
943945001977	DNA binding site [nucleotide binding]
943945001978	substrate interaction site [chemical binding]; other site
943945001979	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
943945001980	E3 interaction surface; other site
943945001981	lipoyl attachment site [posttranslational modification]; other site
943945001982	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
943945001983	E3 interaction surface; other site
943945001984	lipoyl attachment site [posttranslational modification]; other site
943945001985	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
943945001986	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
943945001987	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
943945001988	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
943945001989	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11857
943945001990	e3 binding domain; Region: E3_binding; pfam02817
943945001991	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
943945001992	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
943945001993	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
943945001994	alpha subunit interface [polypeptide binding]; other site
943945001995	TPP binding site [chemical binding]; other site
943945001996	heterodimer interface [polypeptide binding]; other site
943945001997	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
943945001998	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
943945001999	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
943945002000	tetramer interface [polypeptide binding]; other site
943945002001	TPP-binding site [chemical binding]; other site
943945002002	heterodimer interface [polypeptide binding]; other site
943945002003	phosphorylation loop region [posttranslational modification]
943945002004	Fic family protein [Function unknown]; Region: COG3177
943945002005	Fic/DOC family; Region: Fic; pfam02661
943945002006	Transposase, Mutator family; Region: Transposase_mut; pfam00872
943945002007	MULE transposase domain; Region: MULE; pfam10551
943945002008	Integrase core domain; Region: rve; pfam00665
943945002009	Integrase core domain; Region: rve_3; cl15866
943945002010	AAA-like domain; Region: AAA_10; pfam12846
943945002011	Domain of unknown function DUF87; Region: DUF87; pfam01935
943945002012	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
943945002013	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
943945002014	dimer interface [polypeptide binding]; other site
943945002015	ssDNA binding site [nucleotide binding]; other site
943945002016	tetramer (dimer of dimers) interface [polypeptide binding]; other site
943945002017	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
943945002018	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
943945002019	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
943945002020	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
943945002021	Mitochondrial inner membrane protein; Region: Mitofilin; pfam09731
943945002022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945002023	Walker A/P-loop; other site
943945002024	ATP binding site [chemical binding]; other site
943945002025	ABC transporter; Region: ABC_tran; pfam00005
943945002026	Q-loop/lid; other site
943945002027	ABC transporter signature motif; other site
943945002028	Walker B; other site
943945002029	D-loop; other site
943945002030	H-loop/switch region; other site
943945002031	MULE transposase domain; Region: MULE; pfam10551
943945002032	MULE transposase domain; Region: MULE; pfam10551
943945002033	Protein of unknown function (DUF402); Region: DUF402; cl00979
943945002034	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; cl17236
943945002035	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
943945002036	Helix-turn-helix domain; Region: HTH_38; pfam13936
943945002037	Integrase core domain; Region: rve; pfam00665
943945002038	5'-3' exonuclease; Provisional; Region: PRK14976
943945002039	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
943945002040	active site
943945002041	metal binding site 1 [ion binding]; metal-binding site
943945002042	putative 5' ssDNA interaction site; other site
943945002043	metal binding site 3; metal-binding site
943945002044	metal binding site 2 [ion binding]; metal-binding site
943945002045	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
943945002046	putative DNA binding site [nucleotide binding]; other site
943945002047	putative metal binding site [ion binding]; other site
943945002048	DNA polymerase III DnaE; Validated; Region: dnaE; PRK07135
943945002049	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
943945002050	active site
943945002051	PHP Thumb interface [polypeptide binding]; other site
943945002052	OB-fold nucleic acid binding domain; Region: tRNA_anti; pfam01336
943945002053	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
943945002054	ribosome recycling factor; Reviewed; Region: frr; PRK00083
943945002055	hinge region; other site
943945002056	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
943945002057	putative nucleotide binding site [chemical binding]; other site
943945002058	uridine monophosphate binding site [chemical binding]; other site
943945002059	homohexameric interface [polypeptide binding]; other site
943945002060	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
943945002061	nucleotide binding site/active site [active]
943945002062	HIT family signature motif; other site
943945002063	catalytic residue [active]
943945002064	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
943945002065	IHF - DNA interface [nucleotide binding]; other site
943945002066	IHF dimer interface [polypeptide binding]; other site
943945002067	Recombination protein U; Region: RecU; cl01314
943945002068	Competence protein; Region: Competence; cl00471
943945002069	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
943945002070	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
943945002071	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
943945002072	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
943945002073	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
943945002074	S-adenosylmethionine binding site [chemical binding]; other site
943945002075	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
943945002076	active site
943945002077	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
943945002078	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
943945002079	trmE is a tRNA modification GTPase; Region: trmE; cd04164
943945002080	G1 box; other site
943945002081	GTP/Mg2+ binding site [chemical binding]; other site
943945002082	Switch I region; other site
943945002083	G2 box; other site
943945002084	Switch II region; other site
943945002085	G3 box; other site
943945002086	G4 box; other site
943945002087	G5 box; other site
943945002088	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
943945002089	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
943945002090	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
943945002091	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
943945002092	active site turn [active]
943945002093	phosphorylation site [posttranslational modification]
943945002094	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
943945002095	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
943945002096	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
943945002097	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
943945002098	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
943945002099	active site
943945002100	HIGH motif; other site
943945002101	KMSKS motif; other site
943945002102	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
943945002103	tRNA binding surface [nucleotide binding]; other site
943945002104	anticodon binding site; other site
943945002105	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
943945002106	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
943945002107	S-adenosylmethionine binding site [chemical binding]; other site
943945002108	ribonuclease R; Region: RNase_R; TIGR02063
943945002109	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
943945002110	RNB domain; Region: RNB; pfam00773
943945002111	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
943945002112	RNA binding site [nucleotide binding]; other site
943945002113	Guanylate kinase; Region: Guanylate_kin; pfam00625
943945002114	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
943945002115	catalytic site [active]
943945002116	G-X2-G-X-G-K; other site
943945002117	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
943945002118	active site
943945002119	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
943945002120	Catalytic domain of Protein Kinases; Region: PKc; cd00180
943945002121	active site
943945002122	ATP binding site [chemical binding]; other site
943945002123	substrate binding site [chemical binding]; other site
943945002124	activation loop (A-loop); other site
943945002125	GTPase RsgA; Reviewed; Region: PRK00098
943945002126	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
943945002127	RNA binding site [nucleotide binding]; other site
943945002128	homodimer interface [polypeptide binding]; other site
943945002129	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
943945002130	GTPase/Zn-binding domain interface [polypeptide binding]; other site
943945002131	GTP/Mg2+ binding site [chemical binding]; other site
943945002132	G4 box; other site
943945002133	G5 box; other site
943945002134	G1 box; other site
943945002135	Switch I region; other site
943945002136	G2 box; other site
943945002137	G3 box; other site
943945002138	Switch II region; other site
943945002139	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
943945002140	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
943945002141	substrate binding site [chemical binding]; other site
943945002142	hexamer interface [polypeptide binding]; other site
943945002143	metal binding site [ion binding]; metal-binding site
943945002144	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
943945002145	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
943945002146	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
943945002147	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
943945002148	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
943945002149	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
943945002150	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
943945002151	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
943945002152	Hpr binding site; other site
943945002153	active site
943945002154	homohexamer subunit interaction site [polypeptide binding]; other site
943945002155	PBP superfamily domain; Region: PBP_like_2; cl17296
943945002156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945002157	dimer interface [polypeptide binding]; other site
943945002158	conserved gate region; other site
943945002159	putative PBP binding loops; other site
943945002160	ABC-ATPase subunit interface; other site
943945002161	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
943945002162	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945002163	dimer interface [polypeptide binding]; other site
943945002164	conserved gate region; other site
943945002165	putative PBP binding loops; other site
943945002166	ABC-ATPase subunit interface; other site
943945002167	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
943945002168	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
943945002169	Walker A/P-loop; other site
943945002170	ATP binding site [chemical binding]; other site
943945002171	Q-loop/lid; other site
943945002172	ABC transporter signature motif; other site
943945002173	Walker B; other site
943945002174	D-loop; other site
943945002175	H-loop/switch region; other site
943945002176	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
943945002177	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
943945002178	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
943945002179	interface (dimer of trimers) [polypeptide binding]; other site
943945002180	Substrate-binding/catalytic site; other site
943945002181	Zn-binding sites [ion binding]; other site
943945002182	thymidine kinase; Provisional; Region: PRK04296
943945002183	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
943945002184	Target Sequence
943945002185	Mycoplasma phage phiMFV1-2. K. S. Wise and the colleagues have demonstrated the mobility, replication of this prophage and its effect on the mycoplasma surface phenotype. The unique coiled-coil membrane surface protein, Mem, and hypothetical surface lipoproteins expressed from phiMFV1 were considered to associate with the specific, selectable phenotypic traits of the mycoplasma species. [PMID: 15186419]
943945002186	Predicted endonuclease (RecB family) [DNA replication, recombination, and repair]; Region: COG4998
943945002187	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
943945002188	active site
943945002189	Int/Topo IB signature motif; other site
943945002190	catalytic residues [active]
943945002191	DNA binding site [nucleotide binding]
943945002192	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
943945002193	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
943945002194	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
943945002195	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
943945002196	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
943945002197	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
943945002198	Walker A motif; other site
943945002199	ATP binding site [chemical binding]; other site
943945002200	Walker B motif; other site
943945002201	Target Sequence
943945002202	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
943945002203	AAA domain; Region: AAA_14; pfam13173
943945002204	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
943945002205	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
943945002206	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945002207	dimer interface [polypeptide binding]; other site
943945002208	conserved gate region; other site
943945002209	putative PBP binding loops; other site
943945002210	ABC-ATPase subunit interface; other site
943945002211	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
943945002212	dimer interface [polypeptide binding]; other site
943945002213	conserved gate region; other site
943945002214	putative PBP binding loops; other site
943945002215	ABC-ATPase subunit interface; other site
943945002216	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945002217	AAA domain; Region: AAA_21; pfam13304
943945002218	Walker A/P-loop; other site
943945002219	ATP binding site [chemical binding]; other site
943945002220	Q-loop/lid; other site
943945002221	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
943945002222	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945002223	ABC transporter signature motif; other site
943945002224	Walker B; other site
943945002225	D-loop; other site
943945002226	H-loop/switch region; other site
943945002227	TOBE domain; Region: TOBE_2; pfam08402
943945002228	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
943945002229	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
943945002230	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
943945002231	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
943945002232	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
943945002233	Protein of unknown function (DUF1640); Region: DUF1640; pfam07798
943945002234	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
943945002235	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945002236	active site
943945002237	HIGH motif; other site
943945002238	nucleotide binding site [chemical binding]; other site
943945002239	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
943945002240	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945002241	Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: CysS; COG0215
943945002242	active site
943945002243	HIGH motif; other site
943945002244	nucleotide binding site [chemical binding]; other site
943945002245	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
943945002246	active site
943945002247	KMSKS motif; other site
943945002248	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
943945002249	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
943945002250	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
943945002251	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
943945002252	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
943945002253	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
943945002254	putative homodimer interface [polypeptide binding]; other site
943945002255	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
943945002256	heterodimer interface [polypeptide binding]; other site
943945002257	homodimer interface [polypeptide binding]; other site
943945002258	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
943945002259	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; cl17726
943945002260	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
943945002261	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
943945002262	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
943945002263	active site
943945002264	peptide chain release factor 1; Validated; Region: prfA; PRK00591
943945002265	This domain is found in peptide chain release factors; Region: PCRF; smart00937
943945002266	RF-1 domain; Region: RF-1; pfam00472
943945002267	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
943945002268	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
943945002269	S-adenosylmethionine binding site [chemical binding]; other site
943945002270	acyl carrier protein; Provisional; Region: acpP; PRK00982
943945002271	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
943945002272	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
943945002273	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
943945002274	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
943945002275	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945002276	Walker A/P-loop; other site
943945002277	ATP binding site [chemical binding]; other site
943945002278	Q-loop/lid; other site
943945002279	ABC transporter signature motif; other site
943945002280	Walker B; other site
943945002281	D-loop; other site
943945002282	H-loop/switch region; other site
943945002283	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
943945002284	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945002285	Walker A motif; other site
943945002286	ATP binding site [chemical binding]; other site
943945002287	Walker B motif; other site
943945002288	arginine finger; other site
943945002289	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
943945002290	recombination protein RecR; Reviewed; Region: recR; PRK00076
943945002291	RecR protein; Region: RecR; pfam02132
943945002292	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
943945002293	active site
943945002294	metal binding site [ion binding]; metal-binding site
943945002295	thymidylate kinase; Validated; Region: tmk; PRK00698
943945002296	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
943945002297	TMP-binding site; other site
943945002298	ATP-binding site [chemical binding]; other site
943945002299	DNA polymerase III subunit delta'; Validated; Region: PRK07132
943945002300	DNA polymerase III subunit delta'; Validated; Region: PRK08485
943945002301	Predicted methyltransferases [General function prediction only]; Region: COG0313
943945002302	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
943945002303	putative SAM binding site [chemical binding]; other site
943945002304	putative homodimer interface [polypeptide binding]; other site
943945002305	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
943945002306	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
943945002307	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
943945002308	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
943945002309	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
943945002310	Helix-turn-helix domain; Region: HTH_38; pfam13936
943945002311	Integrase core domain; Region: rve; pfam00665
943945002312	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
943945002313	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945002314	Walker A/P-loop; other site
943945002315	ATP binding site [chemical binding]; other site
943945002316	Q-loop/lid; other site
943945002317	ABC transporter signature motif; other site
943945002318	Walker B; other site
943945002319	D-loop; other site
943945002320	H-loop/switch region; other site
943945002321	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
943945002322	Walker A/P-loop; other site
943945002323	ATP binding site [chemical binding]; other site
943945002324	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
943945002325	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
943945002326	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
943945002327	TM-ABC transporter signature motif; other site
943945002328	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
943945002329	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
943945002330	TM-ABC transporter signature motif; other site
943945002331	DNA polymerase III PolC; Validated; Region: polC; PRK00448
943945002332	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
943945002333	catalytic residues [active]
943945002334	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
943945002335	SmpB-tmRNA interface; other site
943945002336	Transcriptional regulators [Transcription]; Region: PurR; COG1609
943945002337	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
943945002338	DNA binding site [nucleotide binding]
943945002339	domain linker motif; other site
943945002340	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
943945002341	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
943945002342	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
943945002343	ATP binding site [chemical binding]; other site
943945002344	Mg2+ binding site [ion binding]; other site
943945002345	G-X-G motif; other site
943945002346	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
943945002347	anchoring element; other site
943945002348	dimer interface [polypeptide binding]; other site
943945002349	ATP binding site [chemical binding]; other site
943945002350	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
943945002351	active site
943945002352	putative metal-binding site [ion binding]; other site
943945002353	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
943945002354	Uncharacterized conserved protein [Function unknown]; Region: COG1284
943945002355	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
943945002356	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
943945002357	seryl-tRNA synthetase; Provisional; Region: PRK05431
943945002358	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
943945002359	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
943945002360	dimer interface [polypeptide binding]; other site
943945002361	active site
943945002362	motif 1; other site
943945002363	motif 2; other site
943945002364	motif 3; other site
943945002365	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
943945002366	RNase P protein component [Translation, ribosomal structure and biogenesis]; Region: RnpA; COG0594
943945002367	putative inner membrane protein translocase component YidC; Provisional; Region: PRK02201
943945002368	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
943945002369	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
943945002370	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
943945002371	TPP-binding site [chemical binding]; other site
943945002372	dimer interface [polypeptide binding]; other site
943945002373	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
943945002374	PYR/PP interface [polypeptide binding]; other site
943945002375	dimer interface [polypeptide binding]; other site
943945002376	TPP binding site [chemical binding]; other site
943945002377	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
943945002378	TM2 domain; Region: TM2; pfam05154
943945002379	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
943945002380	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
943945002381	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
943945002382	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
943945002383	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
943945002384	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
943945002385	RNA/DNA hybrid binding site [nucleotide binding]; other site
943945002386	active site
943945002387	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
943945002388	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
943945002389	RNA binding surface [nucleotide binding]; other site
943945002390	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
943945002391	active site
943945002392	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
943945002393	Chromate transporter; Region: Chromate_transp; pfam02417
943945002394	ALDH subfamily: Coniferyl aldehyde dehydrogenase, ALDH families 3, 13, and 14, and other related proteins; Region: ALDH_F3-13-14_CALDH-like; cd07087
943945002395	NAD(P) binding site [chemical binding]; other site
943945002396	catalytic residues [active]
943945002397	D-allose kinase; Provisional; Region: PRK09698
943945002398	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
943945002399	nucleotide binding site [chemical binding]; other site
943945002400	Ion channel; Region: Ion_trans_2; pfam07885
943945002401	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
943945002402	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
943945002403	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
943945002404	potential frameshift: common BLAST hit: gi|308190345|ref|YP_003923276.1| tRNA (guanine-N(7)-)-methyltransferase
943945002405	Putative methyltransferase; Region: Methyltransf_4; cl17290
943945002406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
943945002407	S-adenosylmethionine binding site [chemical binding]; other site
943945002408	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
943945002409	non-specific DNA binding site [nucleotide binding]; other site
943945002410	salt bridge; other site
943945002411	sequence-specific DNA binding site [nucleotide binding]; other site
943945002412	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
943945002413	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
943945002414	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
943945002415	ATP binding site [chemical binding]; other site
943945002416	putative Mg++ binding site [ion binding]; other site
943945002417	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
943945002418	Methyltransferase domain; Region: Methyltransf_26; pfam13659
943945002419	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945002420	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
943945002421	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945002422	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
943945002423	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
943945002424	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
943945002425	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
943945002426	catalytic residues [active]
943945002427	catalytic nucleophile [active]
943945002428	Presynaptic Site I dimer interface [polypeptide binding]; other site
943945002429	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
943945002430	Synaptic Flat tetramer interface [polypeptide binding]; other site
943945002431	Synaptic Site I dimer interface [polypeptide binding]; other site
943945002432	DNA binding site [nucleotide binding]
943945002433	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945002434	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
943945002435	Walker A motif; other site
943945002436	ATP binding site [chemical binding]; other site
943945002437	Walker B motif; other site
943945002438	arginine finger; other site
943945002439	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945002440	Walker A motif; other site
943945002441	ATP binding site [chemical binding]; other site
943945002442	Walker B motif; other site
943945002443	arginine finger; other site
943945002444	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
943945002445	DNA polymerase III PolC; Validated; Region: polC; PRK00448
943945002446	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
943945002447	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
943945002448	generic binding surface II; other site
943945002449	generic binding surface I; other site
943945002450	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
943945002451	active site
943945002452	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
943945002453	active site
943945002454	catalytic site [active]
943945002455	substrate binding site [chemical binding]; other site
943945002456	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
943945002457	potential frameshift: common BLAST hit: gi|308190295|ref|YP_003923226.1| transposase for IS1630-like insertion sequence element
943945002458	Helix-turn-helix domain; Region: HTH_38; pfam13936
943945002459	potential frameshift: common BLAST hit: gi|308190214|ref|YP_003923145.1| transposase for IS1630-like insertion sequence element
943945002460	Integrase core domain; Region: rve; pfam00665
943945002461	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
943945002462	prolyl-tRNA synthetase; Provisional; Region: PRK08661
943945002463	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
943945002464	dimer interface [polypeptide binding]; other site
943945002465	motif 1; other site
943945002466	active site
943945002467	motif 2; other site
943945002468	motif 3; other site
943945002469	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
943945002470	anticodon binding site; other site
943945002471	zinc-binding site [ion binding]; other site
943945002472	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
943945002473	Spore germination protein GerPC; Region: GerPC; pfam10737
943945002474	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
943945002475	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
943945002476	Transglutaminase/protease-like homologues; Region: TGc; smart00460
943945002477	inorganic pyrophosphatase; Provisional; Region: PRK02230
943945002478	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
943945002479	dimer interface [polypeptide binding]; other site
943945002480	substrate binding site [chemical binding]; other site
943945002481	metal binding sites [ion binding]; metal-binding site
943945002482	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
943945002483	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
943945002484	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
943945002485	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
943945002486	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
943945002487	Walker A/P-loop; other site
943945002488	ATP binding site [chemical binding]; other site
943945002489	Q-loop/lid; other site
943945002490	ABC transporter signature motif; other site
943945002491	Walker B; other site
943945002492	D-loop; other site
943945002493	H-loop/switch region; other site
943945002494	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
943945002495	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
943945002496	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
943945002497	50S ribosomal protein L11/unknown domain fusion protein; Provisional; Region: PRK14539
943945002498	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
943945002499	23S rRNA interface [nucleotide binding]; other site
943945002500	L7/L12 interface [polypeptide binding]; other site
943945002501	putative thiostrepton binding site; other site
943945002502	L25 interface [polypeptide binding]; other site
943945002503	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
943945002504	mRNA/rRNA interface [nucleotide binding]; other site
943945002505	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
943945002506	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
943945002507	catalytic residue [active]
943945002508	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
943945002509	active site
943945002510	metal-binding site
943945002511	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
943945002512	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
943945002513	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
943945002514	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
943945002515	Walker A/P-loop; other site
943945002516	ATP binding site [chemical binding]; other site
943945002517	Q-loop/lid; other site
943945002518	ABC transporter signature motif; other site
943945002519	Walker B; other site
943945002520	D-loop; other site
943945002521	H-loop/switch region; other site
943945002522	FtsX-like permease family; Region: FtsX; pfam02687
943945002523	FtsX-like permease family; Region: FtsX; pfam02687
943945002524	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
943945002525	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
943945002526	Walker A motif; other site
943945002527	ATP binding site [chemical binding]; other site
943945002528	Walker B motif; other site
943945002529	arginine finger; other site
943945002530	Peptidase family M41; Region: Peptidase_M41; pfam01434
943945002531	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
943945002532	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
943945002533	Ligand Binding Site [chemical binding]; other site
943945002534	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
943945002535	putative active site [active]
943945002536	catalytic residue [active]
943945002537	Family description; Region: UvrD_C_2; pfam13538
943945002538	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
943945002539	AAA domain; Region: AAA_30; pfam13604
943945002540	Family description; Region: UvrD_C_2; pfam13538