-- dump date   	20140619_161532
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
NP_757387.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
NP_757389.1	negatively supercoils closed circular double-stranded DNA
NP_757390.1	negatively supercoils closed circular double-stranded DNA
NP_757391.1	truncated, C-terminal of MYPE9620
NP_757392.1	truncated, N-terminal of MYPE9620
NP_757393.1	truncated
NP_757397.1	MYPE120 paralog
NP_757398.1	paralog family
NP_757408.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
NP_757411.1	binds directly to 23S ribosomal RNA
NP_757412.1	Binds directly to 23S rRNA and is located proximal to the site where elongation factor Tu is bound to the ribosome
NP_757415.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
NP_757416.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
NP_757418.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_757425.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer
NP_757427.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
NP_757433.1	similar to cytadherence-accessory protein HMW1 homolog of Mycoplasma genitalium of MG313, F64234 Expect=2.5e-18, Identities=30%
NP_757437.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
NP_757438.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
NP_757442.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
NP_757446.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
NP_757447.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
NP_757448.2	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
NP_757450.2	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
NP_757451.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
NP_757453.1	Sua5/YciO/YrdC family protein
NP_757456.1	predicted ThiJ family
NP_757457.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NP_757459.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
NP_757464.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_757465.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
NP_757466.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
NP_757467.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
NP_757468.1	forms a direct contact with the tRNA during translation
NP_757472.1	Catalyzes the rate-limiting step in dNTP synthesis
NP_757473.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
NP_757474.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
NP_757475.1	MYPE890 paralog
NP_757476.1	paralog family
NP_757481.1	methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
NP_757482.1	paralog family
NP_757483.1	paralog family
NP_757486.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
NP_757489.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
NP_757490.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NP_757497.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
NP_757499.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP_757500.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
NP_757502.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
NP_757506.1	similar to hydrolase
NP_757509.1	integral membrane protein
NP_757510.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
NP_757514.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NP_757520.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
NP_757532.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
NP_757533.1	ATPase of the PP-loop superfamily
NP_757534.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
NP_757535.1	catalyzes the formation of asparagine from aspartate and ammonia
NP_757540.1	coiled-coil structure containing protein
NP_757542.1	ortholog of cytoskeletal protein HMW2 of M. pneumoniae MPN310, NP_109998, (SwissProt HMW2_MYCPN), predicted coiled-coil structure containing protein
NP_757543.1	predicted coiled-coil structure containing protein
NP_757544.1	similar to cytoskeletal protein HMW2 homolog MG218 of M. genitalium U39701, Expect = 1.1e-20, Identities = 152/631 (24%), predicted coiled-coil structure containing protein
NP_757545.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
NP_757554.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
NP_757559.1	RpiR family
NP_757561.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
NP_757575.1	MYPE3080 paralog
NP_757576.1	catalyzes the hydrolytic cleavage of the 4'-phosphopantetheine residue from ACP
NP_757580.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
NP_757582.1	low similarity to P1-like adhesin precursor of Mycoplasma pirum L19685 Expect=6.3e-03, Identities=19%
NP_757585.1	catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand; in the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.
NP_757587.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
NP_757594.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP_757595.1	in some Mycoplasma, this protein is fused to aspartyl/glutamyl-tRNA amidotransferase subunit C domain
NP_757597.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
NP_757598.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
NP_757601.1	paralog family
NP_757602.1	MYPE2140 paralog
NP_757603.1	MYPE2140 paralog
NP_757612.1	MYPE4220 paralog
NP_757616.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
NP_757621.1	MYPE2360 paralog
NP_757622.1	low similarity to histidine kinase, paralog family
NP_757623.1	MYPE2360 paralog
NP_757624.1	MYPE2360 paralog
NP_757626.1	MYPE2360 paralog
NP_757627.1	MYPE2360 paralog
NP_757633.1	paralog family
NP_757641.1	MYPE2560 paralog, partial
NP_757642.1	MYPE2560 paralog, partial
NP_757643.1	paralog family
NP_757645.1	MYPE2560 paralog
NP_757648.1	MYPE2560 paralog
NP_757652.1	Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes
NP_757653.1	MYPE2560 paralog
NP_757654.1	MYPE2560 paralog
NP_757655.1	MYPE2560 paralog
NP_757661.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
NP_757666.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
NP_757674.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
NP_757675.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
NP_757678.1	phage integrase family
NP_757682.1	similar to beta-glycosidase lacS of Sulfolobus solfataricus AE006893 Expect=7.5e-01, Identities=35%
NP_757687.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
NP_757688.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
NP_757696.1	paralog family
NP_757699.1	ortholog of YwnB of Bacillus subtilis
NP_757700.1	ortholog of YwnA of Bacillus subtilis
NP_757702.1	MYPE2560 paralog
NP_757721.1	with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase
NP_757728.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_757730.1	MYPE8480 paralog
NP_757731.1	MYPE8480 paralog
NP_757732.1	MYPE8480 paralog
NP_757736.1	MYPE3080 paralog
NP_757740.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
NP_757743.1	MYPE960 paralog
NP_757745.1	paralog family
NP_757746.1	MYPE3580 paralog
NP_757747.1	MYPE3580 paralog
NP_757748.1	MYPE3580 paralog
NP_757750.1	MYPE3080 paralog
NP_757751.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
NP_757752.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
NP_757754.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP_757759.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NP_757760.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
NP_757773.2	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
NP_757774.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
NP_757775.2	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif
NP_757790.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_757792.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_757795.1	MYPE2470 paralog
NP_757796.1	MYPE2470 paralog
NP_757800.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
NP_757808.1	paralog family
NP_757809.1	paralog family, similar to Pfam domain Archaea bacterial proteins of unknown function
NP_757817.1	similar to immuno-dominant variable surface antigen of Entamoeba histolytica CAA38847.1, Expect=3.0e-16, Identities=29%
NP_757819.1	paralog family
NP_757820.1	MYPE4340 paralog
NP_757821.1	MYPE4340 paralog
NP_757822.1	MYPE4340 paralog
NP_757826.1	catalyzes the hydrolysis of pyrophosphate to phosphate
NP_757830.1	involved in the peptidyltransferase reaction during translation
NP_757836.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_757837.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
NP_757844.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_757849.1	paralog family
NP_757851.1	MYPE4630 paralog
NP_757852.1	MYPE4630 paralog
NP_757853.1	MYPE4630 paralog
NP_757857.1	paralog family
NP_757858.1	similar to CagA protein of Helicobacter pylori AJ269854, Expect=2.4e-01, Identities=40%
NP_757859.1	MYPE 5680paralog
NP_757860.1	MYPE 5680paralog
NP_757861.1	MYPE 5680paralog
NP_757867.1	MYPE4720 paralog
NP_757869.1	similar to 115 kDa protein of Mycoplasma hyorhinis, Expect=3.7e-162, Identities=34%
NP_757884.1	similar to HMW1 of Mycoplasma pneumoniae, Pfam ELK domain Accession number PF03789
NP_757885.1	paralog family
NP_757886.1	MYPE 4990 paralog
NP_757887.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
NP_757889.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
NP_757906.1	catalyzes the reversible adenylation of nicotinate mononucleotide to nicotinic acid adenine dinucleotide
NP_757912.1	MYPE4230 paralog
NP_757916.1	paralog family
NP_757928.1	MYPE5300 paralog
NP_757931.1	ptsI
NP_757943.1	MYPE3080 paralog
NP_757947.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
NP_757949.1	ortholog of YloN of Bacillus subtilis
NP_757951.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
NP_757953.1	MYPE5680 paralog
NP_757954.1	paralog family
NP_757956.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
NP_757960.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
NP_757978.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
NP_757981.1	MYPE5960 paralog
NP_757982.1	paralog family
NP_757984.1	MYPE5960 paralog
NP_757992.1	paralog family, low similarity to 116 kDa surface antigen of Mycoplasma genitalium Expect=1.4e-09, Identities=22%
NP_757993.1	MYPE6060 paralog
NP_757995.1	catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway
NP_757996.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
NP_757998.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
NP_757999.1	MYPE890 paralog
NP_758006.1	MYPE6410 paralog
NP_758022.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
NP_758025.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
NP_758034.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_758036.1	MYPE6495 and MYPE6500 are predicted as the same gene with a frameshift
NP_758037.1	MYPE6495 and MYPE6500 are predicted as the same gene with a frameshift
NP_758039.1	MYPE6520 and MYPE6525 are predicted as the same gene with a frameshift
NP_758040.1	MYPE6520 and MYPE6525 are predicted as the same gene with a frameshift
NP_758048.1	similar to P69 of Mycoplasma hyorhinis Expect=3.3e-80, Identities=33%
NP_758049.1	MYPE3080 paralog
NP_758050.1	similar to P37 of Mycoplasma hyorhinis Expect=4.3e-54, Identities=35%
NP_758065.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_758073.1	paralog family
NP_758075.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
NP_758083.1	MYPE6970 paralog, similar to  liporotein of Mycoplasma genitalium U39711
NP_758084.1	MYPE6970 paralog, similar to  liporotein of Mycoplasma genitalium U39711
NP_758085.1	paralog family, similar to  liporotein of Mycoplasma genitalium U39711
NP_758086.1	MYPE6970 paralog, similar to  liporotein of Mycoplasma genitalium U39711
NP_758087.1	MYPE6970 paralog, similar to  liporotein of Mycoplasma genitalium U39711
NP_758088.1	MYPE6970 paralog truncated
NP_758089.1	MYPE6970 paralog, similar to  liporotein of Mycoplasma genitalium U39711
NP_758091.1	MYPE7030 and MYPE7035 are predicted as the same gene with a frameshift
NP_758092.1	MYPE7030 and MYPE7035 are predicted as the same gene with a frameshift
NP_758097.1	MYPE7110 paralog
NP_758098.1	MYPE7110 paralog
NP_758101.1	MYPE6850 paralog
NP_758104.1	MYPE6850 paralog
NP_758106.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NP_758107.2	UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway
NP_758108.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization
NP_758111.1	similar to transport protein SgaT
NP_758112.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_758118.1	MYPE960 paralog
NP_758120.1	MYPE2560 paralog
NP_758121.1	similar to OrfE1 of Mycoplasma fermentans AF179376 Expect=4.6e-52, Identities=33%
NP_758122.1	MYPE2560 paralog
NP_758125.1	MYPE8480 paralog
NP_758126.1	MYPE8480 paralog
NP_758128.1	MYPE7375 and MYPE7380 are predicted as the same gene with a frameshift
NP_758129.1	MYPE7375 and MYPE7380 are predicted as the same gene with a frameshift
NP_758138.1	MYPE7490 paralog
NP_758139.1	paralog family
NP_758140.1	MYPE7490 paralog
NP_758141.1	MYPE7490 paralog
NP_758142.1	MYPE7490 paralog
NP_758143.1	MYPE2470 paralog
NP_758144.1	MYPE2470 paralog
NP_758145.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
NP_758147.1	partial sequence of MYPE7590 paralog, similar to lipoprotein of Mycoplasma genitalium U39713 Expect = 7.5e-91, Identities = 32%
NP_758149.1	paralog family, similar to lipoprotein of Mycoplasma genitalium U39713
NP_758150.1	MYPE7590 paralog, similar to lipoprotein of Mycoplasma genitalium U39713
NP_758151.1	MYPE7590 paralog, similar to lipoprotein of Mycoplasma genitalium U39713
NP_758152.1	MYPE7590 paralog, similar to lipoprotein of Mycoplasma genitalium U39713
NP_758155.1	MYPE5960 paralog, Pfam domain DUF234 archaebacterial proteins
NP_758156.1	MYPE7720 paralog
NP_758161.1	MYPE7720 paralog
NP_758162.1	paralog family, predicted integral membrane protein
NP_758163.1	MYPE7720 paralog
NP_758168.1	MYPE7800 paralog
NP_758169.1	paralog family, predicted integral membrane protein
NP_758170.1	MYPE7800 paralog
NP_758172.1	predicted ATPase, MYPE4220 paralog
NP_758173.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_758174.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
NP_758175.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits
NP_758177.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
NP_758178.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
NP_758179.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
NP_758180.1	predicted integral membrane protein, paralog family
NP_758181.1	MYPE7910 paralog
NP_758182.1	MYPE7910 paralog
NP_758186.1	MYPE4720 paralog
NP_758190.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
NP_758195.1	involved in a recombinational process of DNA repair, independent of the recBC complex
NP_758197.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
NP_758200.1	similar to hydrolase of Mycoplasma pneumoniae AE000016 Expect=7.5e-42, Identities=37%, containing Pfam domain TatD related DNase : PF01026
NP_758201.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
NP_758202.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
NP_758215.1	paralog family
NP_758216.1	paralog of MYPE8270
NP_758217.1	paralog of MYPE8270
NP_758218.1	paralog of MYPE8270
NP_758219.1	predicted integral membrane protein
NP_758220.1	predicted integral membrane protein
NP_758224.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NP_758230.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
NP_758231.1	MYPE8450 paralog
NP_758232.1	MYPE8450 paralog
NP_758233.1	paralog family
NP_758235.1	MYPE8480 paralog
NP_758236.1	paralog family
NP_758237.1	MYPE8450 paralog
NP_758242.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_758243.1	MYPE8600 paralog
NP_758248.1	paralog family
NP_758249.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
NP_758252.1	predicted integral membrane protein
NP_758254.1	predicted integral membrane protein
NP_758269.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
NP_758276.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
NP_758282.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
NP_758294.1	MYPE950 paralog
NP_758295.1	MYPE950 paralog
NP_758297.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NP_758298.1	similar to Pfam domain pertussis toxin S1subunit, PF02917
NP_758299.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_758301.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
NP_758302.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
NP_758304.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
NP_758309.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
NP_758310.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
NP_758314.1	predicted bifunctional enzyme
NP_758318.1	MYPE3080 paralog
NP_758323.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
NP_758325.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
NP_758333.1	aldo/keto reductase family, MYPE4720 paralog
NP_758341.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
NP_758342.1	paralog family, predicted integral membrane protein
NP_758343.1	MYPE9600 paralog :C-terminal
NP_758345.1	MYPE9600 paralog :N-terminal
NP_758348.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
NP_758356.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
NP_758358.1	with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene
NP_758359.1	with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene
NP_758361.1	similar to endonuclease
NP_758366.1	paralog of MYPE9860 and MYPE8270
NP_758367.1	paralog of MYPE9860 and MYPE8270
NP_758368.1	MYPE8270 paralog
NP_758373.1	is a component of the macrolide binding site in the peptidyl transferase center
NP_758374.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
NP_758375.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
NP_758376.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
NP_758380.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
NP_758381.1	late assembly protein
NP_758382.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
NP_758383.1	binds 5S rRNA along with protein L5 and L25
NP_758384.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
NP_758385.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NP_758386.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
NP_758387.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
NP_758389.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
NP_758390.1	primary binding protein; helps mediate assembly; involved in translation fidelity
NP_758393.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
NP_758394.1	fusion of L22 and COG4933
NP_758396.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
NP_758397.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
NP_758398.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
NP_758399.2	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
NP_758400.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
NP_758402.1	similar to Pfam domain Bvg accessory factor PF03309
NP_758404.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
NP_758408.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
NP_758409.1	MYPE3080 paralog
NP_758411.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
NP_758414.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
NP_758416.1	participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NP_758418.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
NP_758420.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
NP_758421.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria