-- dump date 20140619_163348 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_974147.1 121633902 4675238 complement(1261..2184) 1 NC_008767.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2184 lpxC 4675238 lpxC Neisseria meningitidis FAM18 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_974147.1 1261 R 272831 CDS YP_974148.1 121633903 4675991 complement(3675..4040) 1 NC_008767.1 truncated pilin 4040 pilS2 4675991 pilS2 Neisseria meningitidis FAM18 truncated pilin YP_974148.1 3675 R 272831 CDS YP_974149.1 121633904 4675992 complement(4069..4398) 1 NC_008767.1 peptidyl-prolyl cis-trans isomerase 4398 fbp 4675992 fbp Neisseria meningitidis FAM18 peptidyl-prolyl cis-trans isomerase YP_974149.1 4069 R 272831 CDS YP_974150.1 121633905 4675837 complement(4476..4694) 1 NC_008767.1 hypothetical protein 4694 4675837 NMC0005 Neisseria meningitidis FAM18 hypothetical protein YP_974150.1 4476 R 272831 CDS YP_974151.1 121633906 4675117 4816..5769 1 NC_008767.1 glycerate dehydrogenase 5769 4675117 NMC0006 Neisseria meningitidis FAM18 glycerate dehydrogenase YP_974151.1 4816 D 272831 CDS YP_974152.1 121633907 4675118 complement(5843..7900) 1 NC_008767.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 7900 metG 4675118 metG Neisseria meningitidis FAM18 methionyl-tRNA synthetase YP_974152.1 5843 R 272831 CDS YP_974153.1 121633908 4676318 complement(8016..9854) 1 NC_008767.1 isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 9854 glmS 4676318 glmS Neisseria meningitidis FAM18 glucosamine--fructose-6-phosphate aminotransferase YP_974153.1 8016 R 272831 CDS YP_974154.1 121633909 4676509 10290..10808 1 NC_008767.1 lipoprotein 10808 4676509 NMC0009 Neisseria meningitidis FAM18 lipoprotein YP_974154.1 10290 D 272831 CDS YP_974155.1 121633910 4675112 complement(11226..12551) 1 NC_008767.1 outer membrane lipoprotein Gna33; membrane-bound lytic murein transglycosylase 12551 gna33 4675112 gna33 Neisseria meningitidis FAM18 membrane-bound lytic murein transglycosylase YP_974155.1 11226 R 272831 CDS YP_974156.1 121633911 4676527 12763..13602 1 NC_008767.1 hypothetical protein 13602 4676527 NMC0011 Neisseria meningitidis FAM18 hypothetical protein YP_974156.1 12763 D 272831 CDS YP_974157.1 121633912 4675114 13599..14765 1 NC_008767.1 hypothetical protein 14765 4675114 NMC0012 Neisseria meningitidis FAM18 hypothetical protein YP_974157.1 13599 D 272831 CDS YP_974158.1 121633913 4675116 15029..16294 1 NC_008767.1 hypothetical protein 16294 4675116 NMC0013 Neisseria meningitidis FAM18 hypothetical protein YP_974158.1 15029 D 272831 CDS YP_974159.1 121633914 4675108 complement(16366..16695) 1 NC_008767.1 phosphonoacetate hydrolase 16695 phnA 4675108 phnA Neisseria meningitidis FAM18 phosphonoacetate hydrolase YP_974159.1 16366 R 272831 CDS YP_974160.1 121633915 4676123 complement(16772..18142) 1 NC_008767.1 UDP-N-acetylglucosamine pyrophosphorylase 18142 glmU 4676123 glmU Neisseria meningitidis FAM18 UDP-N-acetylglucosamine pyrophosphorylase YP_974160.1 16772 R 272831 CDS YP_974161.1 121633916 4676510 complement(18197..19174) 1 NC_008767.1 May be two merged CDSs or a complete CDS which has a frameshift mutation in Neisseria meningitidis serogroup A strain Z2491 at a homopolymeric run. N-terminal region similar and equivalent to Neisseria meningitidis possible hydrolase NMA0286 SWALL:Q9JWN1 (EMBL:AL162752) (243 aa) fasta scores: E(): 1.1e-86, 94.78% id in 230 aa. C-terminal region similar and equivalent to Neisseria meningitidis lipoprotein NMA0285 SWALL:Q9JWN2 (EMBL:AL162752) (90 aa) fasta scores: E(): 4.5e-28, 87.77% id in 90 aa.; hypothetical protein 19174 4676510 NMC0016 Neisseria meningitidis FAM18 hypothetical protein YP_974161.1 18197 R 272831 CDS YP_974162.1 121633917 4675111 19233..20234 1 NC_008767.1 solute-binding periplasmic protein 20234 tbpA 4675111 tbpA Neisseria meningitidis FAM18 solute-binding periplasmic protein YP_974162.1 19233 D 272831 CDS YP_974163.1 121633918 4675208 20328..21176 1 NC_008767.1 hypothetical protein 21176 4675208 NMC0018 Neisseria meningitidis FAM18 hypothetical protein YP_974163.1 20328 D 272831 CDS YP_974164.1 121633919 4675113 21203..21688 1 NC_008767.1 hypothetical protein 21688 4675113 NMC0019 Neisseria meningitidis FAM18 hypothetical protein YP_974164.1 21203 D 272831 CDS YP_974165.1 121633920 4675107 complement(21790..23358) 1 NC_008767.1 trifunctional thioredoxin/methionine sulfoxide reductase A/B protein 23358 pilB 4675107 pilB Neisseria meningitidis FAM18 trifunctional thioredoxin/methionine sulfoxide reductase A/B protein YP_974165.1 21790 R 272831 CDS YP_974166.1 121633921 4676126 23503..24768 1 NC_008767.1 signal recognition particle protein 24768 pilA 4676126 pilA Neisseria meningitidis FAM18 signal recognition particle protein YP_974166.1 23503 D 272831 CDS YP_974167.1 121633922 4676119 complement(25628..26584) 1 NC_008767.1 transposase 26584 4676119 NMC0022 Neisseria meningitidis FAM18 transposase YP_974167.1 25628 R 272831 CDS YP_974168.1 121633923 4675105 complement(26799..27986) 1 NC_008767.1 hypothetical protein 27986 4675105 NMC0023 Neisseria meningitidis FAM18 hypothetical protein YP_974168.1 26799 R 272831 CDS YP_974169.1 121633924 4675106 complement(27987..28271) 1 NC_008767.1 hypothetical protein 28271 4675106 NMC0024 Neisseria meningitidis FAM18 hypothetical protein YP_974169.1 27987 R 272831 CDS YP_974170.1 121633925 4675099 complement(28574..30133) 1 NC_008767.1 TspB protein 30133 4675099 NMC0025 Neisseria meningitidis FAM18 TspB protein YP_974170.1 28574 R 272831 CDS YP_974171.1 121633926 4675104 complement(30552..30854) 1 NC_008767.1 hypothetical protein 30854 4675104 NMC0027 Neisseria meningitidis FAM18 hypothetical protein YP_974171.1 30552 R 272831 CDS YP_974172.1 121633927 4675098 complement(30882..31112) 1 NC_008767.1 hypothetical protein 31112 4675098 NMC0028 Neisseria meningitidis FAM18 hypothetical protein YP_974172.1 30882 R 272831 CDS YP_974173.1 121633928 4675091 complement(31339..31539) 1 NC_008767.1 hypothetical protein 31539 4675091 NMC0029 Neisseria meningitidis FAM18 hypothetical protein YP_974173.1 31339 R 272831 CDS YP_974174.1 121633929 4675096 complement(31543..31854) 1 NC_008767.1 hypothetical protein 31854 4675096 NMC0030 Neisseria meningitidis FAM18 hypothetical protein YP_974174.1 31543 R 272831 CDS YP_974175.1 121633930 4675097 complement(31875..33083) 1 NC_008767.1 hypothetical protein 33083 4675097 NMC0031 Neisseria meningitidis FAM18 hypothetical protein YP_974175.1 31875 R 272831 CDS YP_974176.1 121633931 4675089 34401..37547 1 NC_008767.1 pilus assembly protein PilC 37547 pilC 4675089 pilC Neisseria meningitidis FAM18 pilus assembly protein PilC YP_974176.1 34401 D 272831 CDS YP_974177.1 121633932 4676127 complement(38697..40847) 1 NC_008767.1 hypothetical protein 40847 4676127 NMC0034 Neisseria meningitidis FAM18 hypothetical protein YP_974177.1 38697 R 272831 CDS YP_974178.1 121633933 4675090 complement(41133..42359) 1 NC_008767.1 twitching motility protein PilT 42359 pilU 4675090 pilU Neisseria meningitidis FAM18 twitching motility protein PilT YP_974178.1 41133 R 272831 CDS YP_974179.1 121633934 4676088 complement(42522..43565) 1 NC_008767.1 pilus retraction protein 43565 pilT 4676088 pilT Neisseria meningitidis FAM18 pilus retraction protein YP_974179.1 42522 R 272831 CDS YP_974180.1 121633935 4676031 43685..44371 1 NC_008767.1 hypothetical protein 44371 4676031 NMC0037 Neisseria meningitidis FAM18 hypothetical protein YP_974180.1 43685 D 272831 CDS YP_974181.1 121633936 4675085 44371..44778 1 NC_008767.1 lipoprotein 44778 4675085 NMC0038 Neisseria meningitidis FAM18 lipoprotein YP_974181.1 44371 D 272831 CDS YP_974182.1 121633937 4675086 44827..45618 1 NC_008767.1 pyrroline-5-carboxylate reductase 45618 proC 4675086 proC Neisseria meningitidis FAM18 pyrroline-5-carboxylate reductase YP_974182.1 44827 D 272831 CDS YP_974183.1 121633938 4675872 45765..46181 1 NC_008767.1 DnaK suppressor protein 46181 dksA 4675872 dksA Neisseria meningitidis FAM18 DnaK suppressor protein YP_974183.1 45765 D 272831 CDS YP_974184.1 121633939 4675959 51981..52445 1 NC_008767.1 DNA transport competence protein 52445 4675959 NMC0041 Neisseria meningitidis FAM18 DNA transport competence protein YP_974184.1 51981 D 272831 CDS YP_974185.1 121633940 4675087 complement(52506..52667) 1 NC_008767.1 hypothetical protein 52667 4675087 NMC0042 Neisseria meningitidis FAM18 hypothetical protein YP_974185.1 52506 R 272831 CDS YP_974186.1 121633941 4675088 52714..53835 1 NC_008767.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 53835 dnaJ 4675088 dnaJ Neisseria meningitidis FAM18 molecular chaperone DnaJ YP_974186.1 52714 D 272831 CDS YP_974187.1 121633942 4675943 54031..56049 1 NC_008767.1 inner membrane transport protein 56049 4675943 NMC0044 Neisseria meningitidis FAM18 inner membrane transport protein YP_974187.1 54031 D 272831 CDS YP_974188.1 121633943 4675081 complement(56093..56665) 1 NC_008767.1 dTDP-4-dehydrorhamnose 3,5-epimerase 56665 rfbC 4675081 rfbC Neisseria meningitidis FAM18 dTDP-4-dehydrorhamnose 3,5-epimerase YP_974188.1 56093 R 272831 CDS YP_974189.1 121633944 4675611 complement(56704..57570) 1 NC_008767.1 glucose-1-phosphate thymidylyltransferase 57570 rfbA 4675611 rfbA Neisseria meningitidis FAM18 glucose-1-phosphate thymidylyltransferase YP_974189.1 56704 R 272831 CDS YP_974190.1 121633945 4675560 complement(57633..58700) 1 NC_008767.1 dTDP-glucose 4,6-dehydratase 58700 rfbB 4675560 rfbB Neisseria meningitidis FAM18 dTDP-glucose 4,6-dehydratase YP_974190.1 57633 R 272831 CDS YP_974191.1 121633946 4675614 complement(58816..59835) 1 NC_008767.1 UDP-glucose 4-epimerase 59835 galE 4675614 galE Neisseria meningitidis FAM18 UDP-glucose 4-epimerase YP_974191.1 58816 R 272831 CDS YP_974192.1 121633947 4675084 complement(61225..62607) 1 NC_008767.1 hypothetical protein 62607 4675084 NMC0050 Neisseria meningitidis FAM18 hypothetical protein YP_974192.1 61225 R 272831 CDS YP_974193.1 121633948 4675075 complement(62636..64114) 1 NC_008767.1 alpha-2,9-polysialyltransferase 64114 4675075 NMC0051 Neisseria meningitidis FAM18 alpha-2,9-polysialyltransferase YP_974193.1 62636 R 272831 CDS YP_974194.1 121633949 4675073 complement(64194..65243) 1 NC_008767.1 N-acetylneuraminic acid synthase 65243 siaC 4675073 siaC Neisseria meningitidis FAM18 N-acetylneuraminic acid synthase YP_974194.1 64194 R 272831 CDS YP_974195.1 121633950 4675072 complement(65244..65930) 1 NC_008767.1 acylneuraminate cytidylyltransferase 65930 siaB 4675072 siaB Neisseria meningitidis FAM18 acylneuraminate cytidylyltransferase YP_974195.1 65244 R 272831 CDS YP_974196.1 121633951 4675083 complement(65934..67067) 1 NC_008767.1 N-acetylglucosamine-6-phosphate 2-epimerase 67067 sacA 4675083 sacA Neisseria meningitidis FAM18 N-acetylglucosamine-6-phosphate 2-epimerase YP_974196.1 65934 R 272831 CDS YP_974197.1 121633952 4675121 67202..68377 1 NC_008767.1 capsule polysaccharide export outer membrane protein 68377 ctrA 4675121 ctrA Neisseria meningitidis FAM18 capsule polysaccharide export outer membrane protein YP_974197.1 67202 D 272831 CDS YP_974198.1 121633953 4676616 68392..69555 1 NC_008767.1 capsule polysaccharide export inner-membrane protein 69555 ctrB 4676616 ctrB Neisseria meningitidis FAM18 capsule polysaccharide export inner-membrane protein YP_974198.1 68392 D 272831 CDS YP_974199.1 121633954 4676269 69555..70352 1 NC_008767.1 capsule polysaccharide export inner-membrane protein 70352 ctrC 4676269 ctrC Neisseria meningitidis FAM18 capsule polysaccharide export inner-membrane protein YP_974199.1 69555 D 272831 CDS YP_974200.1 121633955 4676270 70349..70999 1 NC_008767.1 capsule polysaccharide export ATP-binding protein CtrD 70999 ctrD 4676270 ctrD Neisseria meningitidis FAM18 capsule polysaccharide export ATP-binding protein CtrD YP_974200.1 70349 D 272831 CDS YP_974201.1 121633956 4676309 71060..73336 1 NC_008767.1 transcriptional accessory protein 73336 4676309 NMC0059 Neisseria meningitidis FAM18 transcriptional accessory protein YP_974201.1 71060 D 272831 CDS YP_974202.1 121633957 4675070 75521..76588 1 NC_008767.1 dTDP-glucose 4,6-dehydratase 76588 rfbB2 4675070 rfbB2 Neisseria meningitidis FAM18 dTDP-glucose 4,6-dehydratase YP_974202.1 75521 D 272831 CDS YP_974203.1 121633958 4675610 76651..77517 1 NC_008767.1 glucose-1-phosphate thymidylyltransferase 77517 rfbA2 4675610 rfbA2 Neisseria meningitidis FAM18 glucose-1-phosphate thymidylyltransferase YP_974203.1 76651 D 272831 CDS YP_974204.1 121633959 4675613 77556..78110 1 NC_008767.1 dTDP-D-glucose 4,6-dehydratase 78110 rfbC2 4675613 rfbC2 Neisseria meningitidis FAM18 dTDP-D-glucose 4,6-dehydratase YP_974204.1 77556 D 272831 CDS YP_974205.1 121633960 4675541 78134..80248 1 NC_008767.1 capsule polysaccharide modification protein 80248 lipA 4675541 lipA Neisseria meningitidis FAM18 capsule polysaccharide modification protein YP_974205.1 78134 D 272831 CDS YP_974206.1 121633961 4676394 80385..81644 1 NC_008767.1 capsule polysaccharide modification protein 81644 lipB 4676394 lipB Neisseria meningitidis FAM18 capsule polysaccharide modification protein YP_974206.1 80385 D 272831 CDS YP_974207.1 121633962 4676378 82013..83419 1 NC_008767.1 hypothetical protein 83419 4676378 NMC0068 Neisseria meningitidis FAM18 hypothetical protein YP_974207.1 82013 D 272831 CDS YP_974208.1 121633963 4675068 83637..84851 1 NC_008767.1 sodium/glutamate symport carrier protein 84851 gltS 4675068 gltS Neisseria meningitidis FAM18 sodium/glutamate symport carrier protein YP_974208.1 83637 D 272831 CDS YP_974209.1 121633964 4676577 84950..85966 1 NC_008767.1 lipoprotein 85966 4676577 NMC0071 Neisseria meningitidis FAM18 lipoprotein YP_974209.1 84950 D 272831 CDS YP_974210.1 121633965 4675064 85977..86174 1 NC_008767.1 hypothetical protein 86174 4675064 NMC0072 Neisseria meningitidis FAM18 hypothetical protein YP_974210.1 85977 D 272831 CDS YP_974211.1 121633966 4675067 complement(86600..88000) 1 NC_008767.1 outer membrane transport protein 88000 4675067 NMC0073 Neisseria meningitidis FAM18 outer membrane transport protein YP_974211.1 86600 R 272831 CDS YP_974212.1 121633967 4675060 complement(88308..89780) 1 NC_008767.1 pyruvate kinase 89780 pykA 4675060 pykA Neisseria meningitidis FAM18 pyruvate kinase YP_974212.1 88308 R 272831 CDS YP_974213.1 121633968 4675783 90041..90370 1 NC_008767.1 IS1016 transposase, partial CDS 90370 4675783 NMC0075 Neisseria meningitidis FAM18 IS1016 transposase, partial CDS YP_974213.1 90041 D 272831 CDS YP_974214.1 121633969 4675063 91332..91568 1 NC_008767.1 hypothetical protein 91568 4675063 NMC0080 Neisseria meningitidis FAM18 hypothetical protein YP_974214.1 91332 D 272831 CDS YP_974215.1 121633970 4675056 91562..91789 1 NC_008767.1 hypothetical protein 91789 4675056 NMC0081 Neisseria meningitidis FAM18 hypothetical protein YP_974215.1 91562 D 272831 CDS YP_974216.1 121633971 4675059 92161..92349 1 NC_008767.1 hypothetical protein 92349 4675059 NMC0083 Neisseria meningitidis FAM18 hypothetical protein YP_974216.1 92161 D 272831 CDS YP_974217.1 121633972 4675055 92356..92508 1 NC_008767.1 hypothetical protein 92508 4675055 NMC0083A Neisseria meningitidis FAM18 hypothetical protein YP_974217.1 92356 D 272831 CDS YP_974218.1 121633973 4675057 92609..92746 1 NC_008767.1 hypothetical protein 92746 4675057 NMC0084 Neisseria meningitidis FAM18 hypothetical protein YP_974218.1 92609 D 272831 CDS YP_974219.1 121633974 4675052 92791..94056 1 NC_008767.1 protein export protein 94056 4675052 NMC0085 Neisseria meningitidis FAM18 protein export protein YP_974219.1 92791 D 272831 CDS YP_974220.1 121633975 4675053 94059..96146 1 NC_008767.1 protein export protein 96146 4675053 NMC0086 Neisseria meningitidis FAM18 protein export protein YP_974220.1 94059 D 272831 CDS YP_974221.1 121633976 4675049 96416..97423 1 NC_008767.1 IS1106 transposase 97423 4675049 NMC0088 Neisseria meningitidis FAM18 IS1106 transposase YP_974221.1 96416 D 272831 CDS YP_974222.1 121633977 4675050 complement(97605..97751) 1 NC_008767.1 hypothetical protein 97751 4675050 NMC0089 Neisseria meningitidis FAM18 hypothetical protein YP_974222.1 97605 R 272831 CDS YP_974223.1 121633978 4675044 98556..99107 1 NC_008767.1 hypothetical protein 99107 4675044 NMC0092 Neisseria meningitidis FAM18 hypothetical protein YP_974223.1 98556 D 272831 CDS YP_974224.1 121633979 4675046 complement(99384..100043) 1 NC_008767.1 periplasmic peptidase (bacteriocin resistance) 100043 4675046 NMC0093 Neisseria meningitidis FAM18 periplasmic peptidase (bacteriocin resistance) YP_974224.1 99384 R 272831 CDS YP_974225.1 121633980 4675043 complement(100024..100260) 1 NC_008767.1 hypothetical protein 100260 4675043 NMC0094 Neisseria meningitidis FAM18 hypothetical protein YP_974225.1 100024 R 272831 CDS YP_974226.1 121633981 4675045 complement(join(100382..100981,100983..101057)) 1 NC_008767.1 hypothetical protein 101057 4675045 NMC0095 Neisseria meningitidis FAM18 hypothetical protein YP_974226.1 100382 R 272831 CDS YP_974227.1 121633982 4675040 complement(101184..101342) 1 NC_008767.1 lipoprotein 101342 4675040 NMC0096 Neisseria meningitidis FAM18 lipoprotein YP_974227.1 101184 R 272831 CDS YP_974228.1 121633983 4675042 complement(101339..102181) 1 NC_008767.1 hypothetical protein 102181 4675042 NMC0097 Neisseria meningitidis FAM18 hypothetical protein YP_974228.1 101339 R 272831 CDS YP_974229.1 121633984 4675038 102420..103340 1 NC_008767.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 103340 pyrB 4675038 pyrB Neisseria meningitidis FAM18 aspartate carbamoyltransferase YP_974229.1 102420 D 272831 CDS YP_974230.1 121633985 4675790 103350..103808 1 NC_008767.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 103808 pyrI 4675790 pyrI Neisseria meningitidis FAM18 aspartate carbamoyltransferase YP_974230.1 103350 D 272831 CDS YP_974231.1 121633986 4675767 103873..104538 1 NC_008767.1 hypothetical protein 104538 4675767 NMC0100 Neisseria meningitidis FAM18 hypothetical protein YP_974231.1 103873 D 272831 CDS YP_974232.1 121633987 4675039 complement(104601..105818) 1 NC_008767.1 hypothetical protein 105818 4675039 NMC0101 Neisseria meningitidis FAM18 hypothetical protein YP_974232.1 104601 R 272831 CDS YP_974233.1 121633988 4675035 106002..106505 1 NC_008767.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 106505 def 4675035 def Neisseria meningitidis FAM18 peptide deformylase YP_974233.1 106002 D 272831 CDS YP_974234.1 121633989 4675967 106592..107518 1 NC_008767.1 methionyl-tRNA formyltransferase 107518 fmt 4675967 fmt Neisseria meningitidis FAM18 methionyl-tRNA formyltransferase YP_974234.1 106592 D 272831 CDS YP_974235.1 121633990 4676701 107597..108856 1 NC_008767.1 SUN-family protein 108856 4676701 NMC0104 Neisseria meningitidis FAM18 SUN-family protein YP_974235.1 107597 D 272831 CDS YP_974236.1 121633991 4675037 108822..109421 1 NC_008767.1 hypothetical protein 109421 4675037 NMC0105 Neisseria meningitidis FAM18 hypothetical protein YP_974236.1 108822 D 272831 CDS YP_974237.1 121633992 4675033 109421..111538 1 NC_008767.1 two-component sensor kinase 111538 4675033 NMC0106 Neisseria meningitidis FAM18 two-component sensor kinase YP_974237.1 109421 D 272831 CDS YP_974238.1 121633993 4675034 111531..112808 1 NC_008767.1 two-component transcriptional regulator 112808 4675034 NMC0107 Neisseria meningitidis FAM18 two-component transcriptional regulator YP_974238.1 111531 D 272831 CDS YP_974239.1 121633994 4675036 112899..114092 1 NC_008767.1 SMF-family protein 114092 smf 4675036 smf Neisseria meningitidis FAM18 SMF-family protein YP_974239.1 112899 D 272831 CDS YP_974240.1 121633995 4675062 114118..114579 1 NC_008767.1 SMG-family protein 114579 4675062 NMC0109 Neisseria meningitidis FAM18 SMG-family protein YP_974240.1 114118 D 272831 CDS YP_974241.1 121633996 4675032 114651..116957 1 NC_008767.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I 116957 topA 4675032 topA Neisseria meningitidis FAM18 DNA topoisomerase I YP_974241.1 114651 D 272831 CDS YP_974242.1 121633997 4674852 complement(117030..117725) 1 NC_008767.1 hypothetical protein 117725 4674852 NMC0111 Neisseria meningitidis FAM18 hypothetical protein YP_974242.1 117030 R 272831 CDS YP_974243.1 121633998 4675024 complement(join(117745..117978,117980..118297)) 1 NC_008767.1 hypothetical protein 118297 4675024 NMC0112 Neisseria meningitidis FAM18 hypothetical protein YP_974243.1 117745 R 272831 CDS YP_974244.1 121633999 4675028 118416..118793 1 NC_008767.1 hypothetical protein 118793 4675028 NMC0113 Neisseria meningitidis FAM18 hypothetical protein YP_974244.1 118416 D 272831 CDS YP_974245.1 121634000 4675029 118882..119451 1 NC_008767.1 hypothetical protein 119451 4675029 NMC0114 Neisseria meningitidis FAM18 hypothetical protein YP_974245.1 118882 D 272831 CDS YP_974246.1 121634001 4675019 119574..119825 1 NC_008767.1 ferredoxin 119825 4675019 NMC0115 Neisseria meningitidis FAM18 ferredoxin YP_974246.1 119574 D 272831 CDS YP_974247.1 121634002 4675020 120242..121426 1 NC_008767.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 121426 4675020 NMC0116 Neisseria meningitidis FAM18 elongation factor Tu YP_974247.1 120242 D 272831 CDS YP_974248.1 121634003 4675021 121623..121901 1 NC_008767.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 121901 secE 4675021 secE Neisseria meningitidis FAM18 preprotein translocase subunit SecE YP_974248.1 121623 D 272831 CDS YP_974249.1 121634004 4675214 121903..122439 1 NC_008767.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 122439 nusG 4675214 nusG Neisseria meningitidis FAM18 transcription antitermination protein NusG YP_974249.1 121903 D 272831 CDS YP_974250.1 121634005 4676186 122540..122974 1 NC_008767.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 122974 rplK 4676186 rplK Neisseria meningitidis FAM18 50S ribosomal protein L11 YP_974250.1 122540 D 272831 CDS YP_974251.1 121634006 4675465 122974..123669 1 NC_008767.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 123669 rplA 4675465 rplA Neisseria meningitidis FAM18 50S ribosomal protein L1 YP_974251.1 122974 D 272831 CDS YP_974252.1 121634007 4675403 123899..124399 1 NC_008767.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 124399 rplJ 4675403 rplJ Neisseria meningitidis FAM18 50S ribosomal protein L10 YP_974252.1 123899 D 272831 CDS YP_974253.1 121634008 4675464 124457..124828 1 NC_008767.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 124828 rplL 4675464 rplL Neisseria meningitidis FAM18 50S ribosomal protein L7/L12 YP_974253.1 124457 D 272831 CDS YP_974254.1 121634009 4675468 125013..129197 1 NC_008767.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 129197 rpoB 4675468 rpoB Neisseria meningitidis FAM18 DNA-directed RNA polymerase subunit beta YP_974254.1 125013 D 272831 CDS YP_974255.1 121634010 4675257 129354..133529 1 NC_008767.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 133529 rpoC 4675257 rpoC Neisseria meningitidis FAM18 DNA-directed RNA polymerase subunit beta' YP_974255.1 129354 D 272831 CDS YP_974256.1 121634011 4675272 133787..134158 1 NC_008767.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 134158 rpsL 4675272 rpsL Neisseria meningitidis FAM18 30S ribosomal protein S12 YP_974256.1 133787 D 272831 CDS YP_974257.1 121634012 4675230 134276..134746 1 NC_008767.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 134746 rpsG 4675230 rpsG Neisseria meningitidis FAM18 30S ribosomal protein S7 YP_974257.1 134276 D 272831 CDS YP_974258.1 121634013 4675301 134765..136870 1 NC_008767.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 136870 fusA 4675301 fusA Neisseria meningitidis FAM18 elongation factor G YP_974258.1 134765 D 272831 CDS YP_974259.1 121634014 4676668 136958..138142 1 NC_008767.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 138142 4676668 NMC0128 Neisseria meningitidis FAM18 elongation factor Tu YP_974259.1 136958 D 272831 CDS YP_974260.1 121634015 4675022 138160..138471 1 NC_008767.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 138471 rpsJ 4675022 rpsJ Neisseria meningitidis FAM18 30S ribosomal protein S10 YP_974260.1 138160 D 272831 CDS YP_974261.1 121634016 4675016 139475..140119 1 NC_008767.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 140119 rplC 4675016 rplC Neisseria meningitidis FAM18 50S ribosomal protein L3 YP_974261.1 139475 D 272831 CDS YP_974262.1 121634017 4675473 140119..140739 1 NC_008767.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 140739 rplD 4675473 rplD Neisseria meningitidis FAM18 50S ribosomal protein L4 YP_974262.1 140119 D 272831 CDS YP_974263.1 121634018 4675399 140730..141050 1 NC_008767.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 141050 rplW 4675399 rplW Neisseria meningitidis FAM18 50S ribosomal protein L23 YP_974263.1 140730 D 272831 CDS YP_974264.1 121634019 4675442 141056..141889 1 NC_008767.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 141889 rplB 4675442 rplB Neisseria meningitidis FAM18 50S ribosomal protein L2 YP_974264.1 141056 D 272831 CDS YP_974265.1 121634020 4675472 141896..142174 1 NC_008767.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 142174 rpsS 4675472 rpsS Neisseria meningitidis FAM18 30S ribosomal protein S19 YP_974265.1 141896 D 272831 CDS YP_974266.1 121634021 4675128 142183..142512 1 NC_008767.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 142512 rplV 4675128 rplV Neisseria meningitidis FAM18 50S ribosomal protein L22 YP_974266.1 142183 D 272831 CDS YP_974267.1 121634022 4675441 142522..143214 1 NC_008767.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 143214 rpsC 4675441 rpsC Neisseria meningitidis FAM18 30S ribosomal protein S3 YP_974267.1 142522 D 272831 CDS YP_974268.1 121634023 4675246 143198..143614 1 NC_008767.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 143614 rplP 4675246 rplP Neisseria meningitidis FAM18 50S ribosomal protein L16 YP_974268.1 143198 D 272831 CDS YP_974269.1 121634024 4675384 143614..143805 1 NC_008767.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 143805 rpmC 4675384 rpmC Neisseria meningitidis FAM18 50S ribosomal protein L29 YP_974269.1 143614 D 272831 CDS YP_974270.1 121634025 4675438 143805..144068 1 NC_008767.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 144068 rpsQ 4675438 rpsQ Neisseria meningitidis FAM18 30S ribosomal protein S17 YP_974270.1 143805 D 272831 CDS YP_974271.1 121634026 4675218 144290..144658 1 NC_008767.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 144658 rplN 4675218 rplN Neisseria meningitidis FAM18 50S ribosomal protein L14 YP_974271.1 144290 D 272831 CDS YP_974272.1 121634027 4675387 144670..144993 1 NC_008767.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 144993 rplX 4675387 rplX Neisseria meningitidis FAM18 50S ribosomal protein L24 YP_974272.1 144670 D 272831 CDS YP_974273.1 121634028 4675439 145003..145542 1 NC_008767.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 145542 rplE 4675439 rplE Neisseria meningitidis FAM18 50S ribosomal protein L5 YP_974273.1 145003 D 272831 CDS YP_974274.1 121634029 4675400 145545..145850 1 NC_008767.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 145850 rpsN 4675400 rpsN Neisseria meningitidis FAM18 30S ribosomal protein S14 YP_974274.1 145545 D 272831 CDS YP_974275.1 121634030 4675228 145866..146258 1 NC_008767.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 146258 rpsH 4675228 rpsH Neisseria meningitidis FAM18 30S ribosomal protein S8 YP_974275.1 145866 D 272831 CDS YP_974276.1 121634031 4675302 146272..146805 1 NC_008767.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 146805 rplF 4675302 rplF Neisseria meningitidis FAM18 50S ribosomal protein L6 YP_974276.1 146272 D 272831 CDS YP_974277.1 121634032 4675462 146819..147172 1 NC_008767.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 147172 rplR 4675462 rplR Neisseria meningitidis FAM18 50S ribosomal protein L18 YP_974277.1 146819 D 272831 CDS YP_974278.1 121634033 4675381 147191..147709 1 NC_008767.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 147709 rpsE 4675381 rpsE Neisseria meningitidis FAM18 30S ribosomal protein S5 YP_974278.1 147191 D 272831 CDS YP_974279.1 121634034 4675303 147702..147887 1 NC_008767.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 147887 rpmD 4675303 rpmD Neisseria meningitidis FAM18 50S ribosomal protein L30 YP_974279.1 147702 D 272831 CDS YP_974280.1 121634035 4675433 147889..148323 1 NC_008767.1 late assembly protein; 50S ribosomal protein L15 148323 rplO 4675433 rplO Neisseria meningitidis FAM18 50S ribosomal protein L15 YP_974280.1 147889 D 272831 CDS YP_974281.1 121634036 4675388 148335..149645 1 NC_008767.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 149645 secY 4675388 secY Neisseria meningitidis FAM18 preprotein translocase subunit SecY YP_974281.1 148335 D 272831 CDS YP_974282.1 121634037 4675095 149650..149868 1 NC_008767.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 149868 infA 4675095 infA Neisseria meningitidis FAM18 translation initiation factor IF-1 YP_974282.1 149650 D 272831 CDS YP_974283.1 121634038 4675971 149889..150002 1 NC_008767.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 150002 rpmJ 4675971 rpmJ Neisseria meningitidis FAM18 50S ribosomal protein L36 YP_974283.1 149889 D 272831 CDS YP_974284.1 121634039 4675328 150068..150430 1 NC_008767.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 150430 rpsM 4675328 rpsM Neisseria meningitidis FAM18 30S ribosomal protein S13 YP_974284.1 150068 D 272831 CDS YP_974285.1 121634040 4675227 150450..150845 1 NC_008767.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 150845 rpsK 4675227 rpsK Neisseria meningitidis FAM18 30S ribosomal protein S11 YP_974285.1 150450 D 272831 CDS YP_974286.1 121634041 4675229 150865..151485 1 NC_008767.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 151485 rpsD 4675229 rpsD Neisseria meningitidis FAM18 30S ribosomal protein S4 YP_974286.1 150865 D 272831 CDS YP_974287.1 121634042 4675247 151511..152497 1 NC_008767.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 152497 rpoA 4675247 rpoA Neisseria meningitidis FAM18 DNA-directed RNA polymerase subunit alpha YP_974287.1 151511 D 272831 CDS YP_974288.1 121634043 4675256 152521..152889 1 NC_008767.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 152889 rplQ 4675256 rplQ Neisseria meningitidis FAM18 50S ribosomal protein L17 YP_974288.1 152521 D 272831 CDS YP_974289.1 121634044 4675385 153036..153749 1 NC_008767.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 153749 minC 4675385 minC Neisseria meningitidis FAM18 septum formation inhibitor YP_974289.1 153036 D 272831 CDS YP_974290.1 121634045 4676306 153777..154592 1 NC_008767.1 septum site-determining protein 154592 minD 4676306 minD Neisseria meningitidis FAM18 septum site-determining protein YP_974290.1 153777 D 272831 CDS YP_974291.1 121634046 4676299 154596..154859 1 NC_008767.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 154859 minE 4676299 minE Neisseria meningitidis FAM18 cell division topological specificity factor MinE YP_974291.1 154596 D 272831 CDS YP_974292.1 121634047 4676300 154863..155783 1 NC_008767.1 hydrogen peroxide-inducible genes activator 155783 oxyR 4676300 oxyR Neisseria meningitidis FAM18 hydrogen peroxide-inducible genes activator YP_974292.1 154863 D 272831 CDS YP_974293.1 121634048 4676121 complement(156113..158950) 1 NC_008767.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 158950 valS 4676121 valS Neisseria meningitidis FAM18 valyl-tRNA synthetase YP_974293.1 156113 R 272831 CDS YP_974294.1 121634049 4676713 complement(159047..159856) 1 NC_008767.1 zinc transporter ZupT 159856 4676713 NMC0165 Neisseria meningitidis FAM18 zinc transporter ZupT YP_974294.1 159047 R 272831 CDS YP_974295.1 121634050 4675017 complement(160037..161293) 1 NC_008767.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 161293 dadA 4675017 dadA Neisseria meningitidis FAM18 D-amino acid dehydrogenase small subunit YP_974295.1 160037 R 272831 CDS YP_974296.1 121634051 4675996 complement(161372..162763) 1 NC_008767.1 amino-acid transporter 162763 4675996 NMC0167 Neisseria meningitidis FAM18 amino-acid transporter YP_974296.1 161372 R 272831 CDS YP_974297.1 121634052 4675015 complement(163121..163897) 1 NC_008767.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 163897 lpxA 4675015 lpxA Neisseria meningitidis FAM18 UDP-N-acetylglucosamine acyltransferase YP_974297.1 163121 R 272831 CDS YP_974298.1 121634053 4676335 complement(163940..164662) 1 NC_008767.1 hypothetical protein 164662 4676335 NMC0169 Neisseria meningitidis FAM18 hypothetical protein YP_974298.1 163940 R 272831 CDS YP_974299.1 121634054 4675013 complement(164827..165276) 1 NC_008767.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 165276 fabZ 4675013 fabZ Neisseria meningitidis FAM18 (3R)-hydroxymyristoyl-ACP dehydratase YP_974299.1 164827 R 272831 CDS YP_974300.1 121634055 4675842 complement(165310..166356) 1 NC_008767.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 166356 lpxD 4675842 lpxD Neisseria meningitidis FAM18 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_974300.1 165310 R 272831 CDS YP_974301.1 121634056 4676345 complement(166389..166889) 1 NC_008767.1 hypothetical protein 166889 4676345 NMC0172 Neisseria meningitidis FAM18 hypothetical protein YP_974301.1 166389 R 272831 CDS YP_974302.1 121634057 4675012 complement(166955..169348) 1 NC_008767.1 hypothetical protein 169348 omp85 4675012 omp85 Neisseria meningitidis FAM18 hypothetical protein YP_974302.1 166955 R 272831 CDS YP_974303.1 121634058 4676187 complement(169405..170745) 1 NC_008767.1 inner membrane protease 170745 4676187 NMC0174 Neisseria meningitidis FAM18 inner membrane protease YP_974303.1 169405 R 272831 CDS YP_974304.1 121634059 4675014 complement(170780..172015) 1 NC_008767.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 172015 dxr 4675014 dxr Neisseria meningitidis FAM18 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_974304.1 170780 R 272831 CDS YP_974305.1 121634060 4675916 complement(172020..172817) 1 NC_008767.1 phosphatidate cytidylyltransferase 172817 cdsA 4675916 cdsA Neisseria meningitidis FAM18 phosphatidate cytidylyltransferase YP_974305.1 172020 R 272831 CDS YP_974306.1 121634061 4676661 complement(172821..173594) 1 NC_008767.1 undecaprenyl diphosphate synthase 173594 uppS 4676661 uppS Neisseria meningitidis FAM18 undecaprenyl diphosphate synthase YP_974306.1 172821 R 272831 CDS YP_974307.1 121634062 4676670 complement(173623..174180) 1 NC_008767.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 174180 frr 4676670 frr Neisseria meningitidis FAM18 ribosome recycling factor YP_974307.1 173623 R 272831 CDS YP_974308.1 121634063 4676607 complement(174361..175488) 1 NC_008767.1 hypothetical protein 175488 4676607 NMC0179 Neisseria meningitidis FAM18 hypothetical protein YP_974308.1 174361 R 272831 CDS YP_974309.1 121634064 4675011 175739..176227 1 NC_008767.1 hypothetical protein 176227 4675011 NMC0180 Neisseria meningitidis FAM18 hypothetical protein YP_974309.1 175739 D 272831 CDS YP_974310.1 121634065 4675010 176323..176946 1 NC_008767.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 176946 gidB 4675010 gidB Neisseria meningitidis FAM18 16S rRNA methyltransferase GidB YP_974310.1 176323 D 272831 CDS YP_974311.1 121634066 4676605 177045..177818 1 NC_008767.1 hypothetical protein 177818 4676605 NMC0182 Neisseria meningitidis FAM18 hypothetical protein YP_974311.1 177045 D 272831 CDS YP_974312.1 121634067 4675004 complement(178616..179200) 1 NC_008767.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 179200 rnhB 4675004 rnhB Neisseria meningitidis FAM18 ribonuclease HII YP_974312.1 178616 R 272831 CDS YP_974313.1 121634068 4675575 complement(179268..181163) 1 NC_008767.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 181163 gidA 4675575 gidA Neisseria meningitidis FAM18 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_974313.1 179268 R 272831 CDS YP_974314.1 121634069 4676622 complement(181438..182865) 1 NC_008767.1 inner membrane amino-acid transport protein 182865 4676622 NMC0185 Neisseria meningitidis FAM18 inner membrane amino-acid transport protein YP_974314.1 181438 R 272831 CDS YP_974315.1 121634070 4675005 183025..184014 1 NC_008767.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 184014 pdxA 4675005 pdxA Neisseria meningitidis FAM18 4-hydroxythreonine-4-phosphate dehydrogenase YP_974315.1 183025 D 272831 CDS YP_974316.1 121634071 4676135 complement(185095..187854) 1 NC_008767.1 ribonuclease E 187854 rne 4676135 rne Neisseria meningitidis FAM18 ribonuclease E YP_974316.1 185095 R 272831 CDS YP_974317.1 121634072 4675573 188347..189339 1 NC_008767.1 ribosomal large subunit pseudouridine synthase C 189339 rluC 4675573 rluC Neisseria meningitidis FAM18 ribosomal large subunit pseudouridine synthase C YP_974317.1 188347 D 272831 CDS YP_974318.1 121634073 4675593 189405..190559 1 NC_008767.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 190559 lpxB 4675593 lpxB Neisseria meningitidis FAM18 lipid-A-disaccharide synthase YP_974318.1 189405 D 272831 CDS YP_974319.1 121634074 4676344 complement(190769..191158) 1 NC_008767.1 hypothetical protein 191158 4676344 NMC0193 Neisseria meningitidis FAM18 hypothetical protein YP_974319.1 190769 R 272831 CDS YP_974320.1 121634075 4675009 191492..191791 1 NC_008767.1 hypothetical protein 191791 4675009 NMC0194 Neisseria meningitidis FAM18 hypothetical protein YP_974320.1 191492 D 272831 CDS YP_974321.1 121634076 4675006 complement(192055..192864) 1 NC_008767.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 192864 dapB 4675006 dapB Neisseria meningitidis FAM18 dihydrodipicolinate reductase YP_974321.1 192055 R 272831 CDS YP_974322.1 121634077 4675950 complement(192874..193251) 1 NC_008767.1 outer membrane lipoprotein 193251 4675950 NMC0196 Neisseria meningitidis FAM18 outer membrane lipoprotein YP_974322.1 192874 R 272831 CDS YP_974323.1 121634078 4675003 193409..193912 1 NC_008767.1 ferric uptake regulation protein 193912 fur 4675003 fur Neisseria meningitidis FAM18 ferric uptake regulation protein YP_974323.1 193409 D 272831 CDS YP_974324.1 121634079 4676648 193982..194707 1 NC_008767.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 194707 aat 4676648 aat Neisseria meningitidis FAM18 leucyl/phenylalanyl-tRNA--protein transferase YP_974324.1 193982 D 272831 CDS YP_974325.1 121634080 4676294 complement(194955..195986) 1 NC_008767.1 glyceraldehyde 3-phosphate dehydrogenase 195986 gapA 4676294 gapA Neisseria meningitidis FAM18 glyceraldehyde 3-phosphate dehydrogenase YP_974325.1 194955 R 272831 CDS YP_974326.1 121634081 4676637 complement(196185..197024) 1 NC_008767.1 ferredoxin 197024 4676637 NMC0200 Neisseria meningitidis FAM18 ferredoxin YP_974326.1 196185 R 272831 CDS YP_974327.1 121634082 4675001 197173..199149 1 NC_008767.1 inner membrane transport protein 199149 4675001 NMC0201 Neisseria meningitidis FAM18 inner membrane transport protein YP_974327.1 197173 D 272831 CDS YP_974328.1 121634083 4675216 complement(202007..204397) 1 NC_008767.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 204397 gyrB 4675216 gyrB Neisseria meningitidis FAM18 DNA gyrase subunit B YP_974328.1 202007 R 272831 CDS YP_974329.1 121634084 4676507 204553..205539 1 NC_008767.1 hypothetical protein 205539 4676507 NMC0205 Neisseria meningitidis FAM18 hypothetical protein YP_974329.1 204553 D 272831 CDS YP_974330.1 121634085 4674999 205627..207663 1 NC_008767.1 oligopeptidase A 207663 prlC 4674999 prlC Neisseria meningitidis FAM18 oligopeptidase A YP_974330.1 205627 D 272831 CDS YP_974331.1 121634086 4676069 complement(207939..208505) 1 NC_008767.1 hypothetical protein 208505 4676069 NMC0207 Neisseria meningitidis FAM18 hypothetical protein YP_974331.1 207939 R 272831 CDS YP_974332.1 121634087 4675000 complement(208969..209469) 1 NC_008767.1 hypothetical protein 209469 4675000 NMC0209 Neisseria meningitidis FAM18 hypothetical protein YP_974332.1 208969 R 272831 CDS YP_974333.1 121634088 4674996 complement(209923..210369) 1 NC_008767.1 class II pilin PilE 210369 pilE 4674996 pilE Neisseria meningitidis FAM18 class II pilin PilE YP_974333.1 209923 R 272831 CDS YP_974334.1 121634089 4675955 complement(211530..213044) 1 NC_008767.1 catalase 213044 katA 4675955 katA Neisseria meningitidis FAM18 catalase YP_974334.1 211530 R 272831 CDS YP_974335.1 121634090 4675903 213393..214244 1 NC_008767.1 RNA polymerase sigma factor 214244 4675903 NMC0212 Neisseria meningitidis FAM18 RNA polymerase sigma factor YP_974335.1 213393 D 272831 CDS YP_974336.1 121634091 4676140 complement(216671..217888) 1 NC_008767.1 inner membrane transport protein 217888 4676140 NMC0214 Neisseria meningitidis FAM18 inner membrane transport protein YP_974336.1 216671 R 272831 CDS YP_974337.1 121634092 4674992 218313..219269 1 NC_008767.1 inner membrane transport protein 219269 4674992 NMC0215 Neisseria meningitidis FAM18 inner membrane transport protein YP_974337.1 218313 D 272831 CDS YP_974338.1 121634093 4674993 complement(219511..220758) 1 NC_008767.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 220758 fabF 4674993 fabF Neisseria meningitidis FAM18 3-oxoacyl-ACP synthase YP_974338.1 219511 R 272831 CDS YP_974339.1 121634094 4675839 complement(220914..221150) 1 NC_008767.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 221150 acpP 4675839 acpP Neisseria meningitidis FAM18 acyl carrier protein YP_974339.1 220914 R 272831 CDS YP_974340.1 121634095 4675348 221382..222389 1 NC_008767.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 222389 pyrD 4675348 pyrD Neisseria meningitidis FAM18 dihydroorotate dehydrogenase 2 YP_974340.1 221382 D 272831 CDS YP_974341.1 121634096 4675774 222723..223046 1 NC_008767.1 hypothetical protein 223046 4675774 NMC0220 Neisseria meningitidis FAM18 hypothetical protein YP_974341.1 222723 D 272831 CDS YP_974342.1 121634097 4674991 223133..223414 1 NC_008767.1 hypothetical protein 223414 4674991 NMC0221 Neisseria meningitidis FAM18 hypothetical protein YP_974342.1 223133 D 272831 CDS YP_974343.1 121634098 4674987 223467..223940 1 NC_008767.1 hypothetical protein 223940 4674987 NMC0222 Neisseria meningitidis FAM18 hypothetical protein YP_974343.1 223467 D 272831 CDS YP_974344.1 121634099 4674989 224194..224529 1 NC_008767.1 hypothetical protein 224529 4674989 NMC0223 Neisseria meningitidis FAM18 hypothetical protein YP_974344.1 224194 D 272831 CDS YP_974345.1 121634100 4674990 224709..227399 1 NC_008767.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 227399 glnE 4674990 glnE Neisseria meningitidis FAM18 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_974345.1 224709 D 272831 CDS YP_974346.1 121634101 4676610 complement(227699..228391) 1 NC_008767.1 hypothetical protein 228391 4676610 NMC0225 Neisseria meningitidis FAM18 hypothetical protein YP_974346.1 227699 R 272831 CDS YP_974347.1 121634102 4674985 complement(228499..229692) 1 NC_008767.1 inner membrane transport protein 229692 4674985 NMC0226 Neisseria meningitidis FAM18 inner membrane transport protein YP_974347.1 228499 R 272831 CDS YP_974348.1 121634103 4674986 complement(229821..230558) 1 NC_008767.1 LamB/YcsF family protein 230558 4674986 NMC0227 Neisseria meningitidis FAM18 LamB/YcsF family protein YP_974348.1 229821 R 272831 CDS YP_974349.1 121634104 4674988 complement(230545..231474) 1 NC_008767.1 hypothetical protein 231474 4674988 NMC0228 Neisseria meningitidis FAM18 hypothetical protein YP_974349.1 230545 R 272831 CDS YP_974350.1 121634105 4674982 complement(231471..232118) 1 NC_008767.1 hypothetical protein 232118 4674982 NMC0229 Neisseria meningitidis FAM18 hypothetical protein YP_974350.1 231471 R 272831 CDS YP_974351.1 121634106 4674984 232302..234509 1 NC_008767.1 DNA helicase II 234509 uvrD 4674984 uvrD Neisseria meningitidis FAM18 DNA helicase II YP_974351.1 232302 D 272831 CDS YP_974352.1 121634107 4676602 234744..235283 1 NC_008767.1 hypothetical protein 235283 4676602 NMC0231 Neisseria meningitidis FAM18 hypothetical protein YP_974352.1 234744 D 272831 CDS YP_974353.1 121634108 4674980 complement(235473..235688) 1 NC_008767.1 hypothetical protein 235688 4674980 NMC0232 Neisseria meningitidis FAM18 hypothetical protein YP_974353.1 235473 R 272831 CDS YP_974354.1 121634109 4674981 complement(235812..236171) 1 NC_008767.1 hypothetical protein 236171 4674981 NMC0233 Neisseria meningitidis FAM18 hypothetical protein YP_974354.1 235812 R 272831 CDS YP_974355.1 121634110 4674983 236224..236601 1 NC_008767.1 May be truncated at the N-terminus. Similar to Neisseria meningitidis IS1016 transposase NMA0022 SWALL:Q9JX76 (EMBL:AL162752) (125 aa) fasta scores: E(): 2.3e-51, 100% id in 125 aa, and to Haemophilus influenzae insertion sequence IS1016 SWALL:Q48208 (EMBL:X58176) (164 aa) fasta scores: E(): 6.2e-15, 70.58% id in 68 aa; IS1016 transposase 236601 4674983 NMC0234 Neisseria meningitidis FAM18 IS1016 transposase YP_974355.1 236224 D 272831 CDS YP_974356.1 121634111 4674979 236755..237420 1 NC_008767.1 hypothetical protein 237420 4674979 NMC0235 Neisseria meningitidis FAM18 hypothetical protein YP_974356.1 236755 D 272831 CDS YP_974357.1 121634112 4674977 237401..238894 1 NC_008767.1 hypothetical protein 238894 4674977 NMC0236 Neisseria meningitidis FAM18 hypothetical protein YP_974357.1 237401 D 272831 CDS YP_974358.1 121634113 4674976 239356..239712 1 NC_008767.1 NADH dehydrogenase I subunit A 239712 nuoA 4674976 nuoA Neisseria meningitidis FAM18 NADH dehydrogenase I subunit A YP_974358.1 239356 D 272831 CDS YP_974359.1 121634114 4676201 239703..240185 1 NC_008767.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 240185 nuoB 4676201 nuoB Neisseria meningitidis FAM18 NADH dehydrogenase subunit B YP_974359.1 239703 D 272831 CDS YP_974360.1 121634115 4676202 240198..240791 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 240791 nuoC 4676202 nuoC Neisseria meningitidis FAM18 NADH dehydrogenase subunit C YP_974360.1 240198 D 272831 CDS YP_974361.1 121634116 4676206 240781..242037 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 242037 nuoD 4676206 nuoD Neisseria meningitidis FAM18 NADH dehydrogenase subunit D YP_974361.1 240781 D 272831 CDS YP_974362.1 121634117 4676207 242037..242510 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 242510 nuoE 4676207 nuoE Neisseria meningitidis FAM18 NADH dehydrogenase subunit E YP_974362.1 242037 D 272831 CDS YP_974363.1 121634118 4676191 242900..244201 1 NC_008767.1 NADH dehydrogenase I subunit F 244201 nuoF 4676191 nuoF Neisseria meningitidis FAM18 NADH dehydrogenase I subunit F YP_974363.1 242900 D 272831 CDS YP_974364.1 121634119 4676192 244201..244638 1 NC_008767.1 hypothetical protein 244638 4676192 NMC0243 Neisseria meningitidis FAM18 hypothetical protein YP_974364.1 244201 D 272831 CDS YP_974365.1 121634120 4674978 244928..247189 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 247189 nuoG 4674978 nuoG Neisseria meningitidis FAM18 NADH dehydrogenase subunit G YP_974365.1 244928 D 272831 CDS YP_974366.1 121634121 4675963 247186..248268 1 NC_008767.1 NADH dehydrogenase I subunit H 248268 nuoH 4675963 nuoH Neisseria meningitidis FAM18 NADH dehydrogenase I subunit H YP_974366.1 247186 D 272831 CDS YP_974367.1 121634122 4675964 248349..248828 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 248828 nuoI 4675964 nuoI Neisseria meningitidis FAM18 NADH dehydrogenase subunit I YP_974367.1 248349 D 272831 CDS YP_974368.1 121634123 4676199 248840..249511 1 NC_008767.1 NADH dehydrogenase I subunit J 249511 nuoJ 4676199 nuoJ Neisseria meningitidis FAM18 NADH dehydrogenase I subunit J YP_974368.1 248840 D 272831 CDS YP_974369.1 121634124 4676200 249508..249813 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 249813 nuoK 4676200 nuoK Neisseria meningitidis FAM18 NADH dehydrogenase subunit K YP_974369.1 249508 D 272831 CDS YP_974370.1 121634125 4676194 249847..250422 1 NC_008767.1 hypothetical protein 250422 4676194 NMC0249 Neisseria meningitidis FAM18 hypothetical protein YP_974370.1 249847 D 272831 CDS YP_974371.1 121634126 4674971 250546..250887 1 NC_008767.1 hypothetical protein 250887 4674971 NMC0250 Neisseria meningitidis FAM18 hypothetical protein YP_974371.1 250546 D 272831 CDS YP_974372.1 121634127 4674972 250936..252960 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 252960 nuoL 4674972 nuoL Neisseria meningitidis FAM18 NADH dehydrogenase subunit L YP_974372.1 250936 D 272831 CDS YP_974373.1 121634128 4676195 253049..254545 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 254545 nuoM 4676195 nuoM Neisseria meningitidis FAM18 NADH dehydrogenase subunit M YP_974373.1 253049 D 272831 CDS YP_974374.1 121634129 4676006 254555..256000 1 NC_008767.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 256000 nuoN 4676006 nuoN Neisseria meningitidis FAM18 NADH dehydrogenase subunit N YP_974374.1 254555 D 272831 CDS YP_974375.1 121634130 4676007 256061..256411 1 NC_008767.1 inner membrane protei 256411 4676007 NMC0254 Neisseria meningitidis FAM18 inner membrane protei YP_974375.1 256061 D 272831 CDS YP_974376.1 121634131 4674974 complement(256520..257416) 1 NC_008767.1 geranyltranstransferase 257416 ispA 4674974 ispA Neisseria meningitidis FAM18 geranyltranstransferase YP_974376.1 256520 R 272831 CDS YP_974377.1 121634132 4676434 complement(257400..257624) 1 NC_008767.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 257624 xseB 4676434 xseB Neisseria meningitidis FAM18 exodeoxyribonuclease VII small subunit YP_974377.1 257400 R 272831 CDS YP_974378.1 121634133 4676666 complement(257735..258658) 1 NC_008767.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 258658 4676666 NMC0257 Neisseria meningitidis FAM18 ribosome-associated GTPase YP_974378.1 257735 R 272831 CDS YP_974379.1 121634134 4674973 complement(258663..260516) 1 NC_008767.1 ABC transporter 260516 4674973 NMC0258 Neisseria meningitidis FAM18 ABC transporter YP_974379.1 258663 R 272831 CDS YP_974380.1 121634135 4674975 complement(260682..261266) 1 NC_008767.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 261266 ruvA 4674975 ruvA Neisseria meningitidis FAM18 Holliday junction DNA helicase RuvA YP_974380.1 260682 R 272831 CDS YP_974381.1 121634136 4675529 complement(261348..261728) 1 NC_008767.1 hypothetical protein 261728 4675529 NMC0260 Neisseria meningitidis FAM18 hypothetical protein YP_974381.1 261348 R 272831 CDS YP_974382.1 121634137 4674970 complement(261728..262447) 1 NC_008767.1 hypothetical protein 262447 4674970 NMC0261 Neisseria meningitidis FAM18 hypothetical protein YP_974382.1 261728 R 272831 CDS YP_974383.1 121634138 4674968 complement(262577..263041) 1 NC_008767.1 tRNA/rRNA methyltransferase 263041 4674968 NMC0262 Neisseria meningitidis FAM18 tRNA/rRNA methyltransferase YP_974383.1 262577 R 272831 CDS YP_974384.1 121634139 4674969 complement(263106..263831) 1 NC_008767.1 hypothetical protein 263831 4674969 NMC0263 Neisseria meningitidis FAM18 hypothetical protein YP_974384.1 263106 R 272831 CDS YP_974385.1 121634140 4674966 263803..264573 1 NC_008767.1 hydrolase 264573 4674966 NMC0264 Neisseria meningitidis FAM18 hydrolase YP_974385.1 263803 D 272831 CDS YP_974386.1 121634141 4674965 264575..265363 1 NC_008767.1 hypothetical protein 265363 4674965 NMC0265 Neisseria meningitidis FAM18 hypothetical protein YP_974386.1 264575 D 272831 CDS YP_974387.1 121634142 4674967 265817..266113 1 NC_008767.1 hypothetical protein 266113 4674967 NMC0267 Neisseria meningitidis FAM18 hypothetical protein YP_974387.1 265817 D 272831 CDS YP_974388.1 121634143 4674964 complement(266719..269019) 1 NC_008767.1 ATP-dependent DNA helicase 269019 recQ 4674964 recQ Neisseria meningitidis FAM18 ATP-dependent DNA helicase YP_974388.1 266719 R 272831 CDS YP_974389.1 121634144 4675741 complement(269085..269867) 1 NC_008767.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 269867 trpC 4675741 trpC Neisseria meningitidis FAM18 indole-3-glycerol phosphate synthase YP_974389.1 269085 R 272831 CDS YP_974390.1 121634145 4675187 complement(269918..270874) 1 NC_008767.1 hypothetical protein 270874 4675187 NMC0271 Neisseria meningitidis FAM18 hypothetical protein YP_974390.1 269918 R 272831 CDS YP_974391.1 121634146 4674963 complement(271007..272545) 1 NC_008767.1 hypothetical protein 272545 4674963 NMC0272 Neisseria meningitidis FAM18 hypothetical protein YP_974391.1 271007 R 272831 CDS YP_974392.1 121634147 4674959 273004..273702 1 NC_008767.1 thiol:disulfide interchange protein 273702 4674959 NMC0273 Neisseria meningitidis FAM18 thiol:disulfide interchange protein YP_974392.1 273004 D 272831 CDS YP_974393.1 121634148 4674958 complement(273759..274763) 1 NC_008767.1 hypothetical protein 274763 4674958 NMC0274 Neisseria meningitidis FAM18 hypothetical protein YP_974393.1 273759 R 272831 CDS YP_974394.1 121634149 4674960 274833..277241 1 NC_008767.1 outer membrane solvent tolerance protein 277241 4674960 NMC0275 Neisseria meningitidis FAM18 outer membrane solvent tolerance protein YP_974394.1 274833 D 272831 CDS YP_974395.1 121634150 4674961 277343..278560 1 NC_008767.1 rotamase 278560 4674961 NMC0276 Neisseria meningitidis FAM18 rotamase YP_974395.1 277343 D 272831 CDS YP_974396.1 121634151 4674962 280407..281615 1 NC_008767.1 hypothetical protein 281615 4674962 NMC0277 Neisseria meningitidis FAM18 hypothetical protein YP_974396.1 280407 D 272831 CDS YP_974397.1 121634152 4674956 281636..281947 1 NC_008767.1 hypothetical protein 281947 4674956 NMC0278 Neisseria meningitidis FAM18 hypothetical protein YP_974397.1 281636 D 272831 CDS YP_974398.1 121634153 4674957 281951..282151 1 NC_008767.1 hypothetical protein 282151 4674957 NMC0279 Neisseria meningitidis FAM18 hypothetical protein YP_974398.1 281951 D 272831 CDS YP_974399.1 121634154 4674954 282378..282608 1 NC_008767.1 hypothetical protein 282608 4674954 NMC0280 Neisseria meningitidis FAM18 hypothetical protein YP_974399.1 282378 D 272831 CDS YP_974400.1 121634155 4674955 282636..282938 1 NC_008767.1 hypothetical protein 282938 4674955 NMC0281 Neisseria meningitidis FAM18 hypothetical protein YP_974400.1 282636 D 272831 CDS YP_974401.1 121634156 4674953 283053..283334 1 NC_008767.1 Doubtful due to large overlap with downstream CDS. Similar to Neisseria meningitidis hypothetical protein NMB1746 SWALL:Q9JY50 (EMBL:AE002524) (96 aa) fasta scores: E(): 0.25, 35.21% id in 71 aa; hypothetical protein 283334 4674953 NMC0282 Neisseria meningitidis FAM18 hypothetical protein YP_974401.1 283053 D 272831 CDS YP_974402.1 121634157 4674951 283285..284916 1 NC_008767.1 TspB protein 284916 tspB 4674951 tspB Neisseria meningitidis FAM18 TspB protein YP_974402.1 283285 D 272831 CDS YP_974403.1 121634158 4674749 285219..285503 1 NC_008767.1 hypothetical protein 285503 4674749 NMC0284 Neisseria meningitidis FAM18 hypothetical protein YP_974403.1 285219 D 272831 CDS YP_974404.1 121634159 4674952 285504..286691 1 NC_008767.1 hypothetical protein 286691 4674952 NMC0285 Neisseria meningitidis FAM18 hypothetical protein YP_974404.1 285504 D 272831 CDS YP_974405.1 121634160 4674948 286906..287862 1 NC_008767.1 invertase/transposase 287862 4674948 NMC0286 Neisseria meningitidis FAM18 invertase/transposase YP_974405.1 286906 D 272831 CDS YP_974406.1 121634161 4674949 complement(288298..290178) 1 NC_008767.1 hypothetical protein 290178 4674949 NMC0288 Neisseria meningitidis FAM18 hypothetical protein YP_974406.1 288298 R 272831 CDS YP_974407.1 121634162 4674950 290487..291119 1 NC_008767.1 hypothetical protein 291119 4674950 NMC0289 Neisseria meningitidis FAM18 hypothetical protein YP_974407.1 290487 D 272831 CDS YP_974408.1 121634163 4674947 291191..292561 1 NC_008767.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 292561 purB 4674947 purB Neisseria meningitidis FAM18 adenylosuccinate lyase YP_974408.1 291191 D 272831 CDS YP_974409.1 121634164 4675799 292641..294509 1 NC_008767.1 inner membrane trans-acylase protein 294509 4675799 NMC0291 Neisseria meningitidis FAM18 inner membrane trans-acylase protein YP_974409.1 292641 D 272831 CDS YP_974410.1 121634165 4674945 complement(295254..297404) 1 NC_008767.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 297404 dinG 4674945 dinG Neisseria meningitidis FAM18 ATP-dependent DNA helicase DinG YP_974410.1 295254 R 272831 CDS YP_974411.1 121634166 4675976 297476..297706 1 NC_008767.1 hypothetical protein 297706 4675976 NMC0294 Neisseria meningitidis FAM18 hypothetical protein YP_974411.1 297476 D 272831 CDS YP_974412.1 121634167 4674946 298148..300736 1 NC_008767.1 deleted EC_number 2.1.1.73; DNA methylase 300736 4674946 NMC0295 Neisseria meningitidis FAM18 DNA methylase YP_974412.1 298148 D 272831 CDS YP_974413.1 121634168 4674941 301098..302063 1 NC_008767.1 insertion element IS1655 transposase 302063 4674941 NMC0297 Neisseria meningitidis FAM18 insertion element IS1655 transposase YP_974413.1 301098 D 272831 CDS YP_974414.1 121634169 4674936 complement(303055..303426) 1 NC_008767.1 hypothetical protein 303426 4674936 NMC0298 Neisseria meningitidis FAM18 hypothetical protein YP_974414.1 303055 R 272831 CDS YP_974415.1 121634170 4674940 complement(303741..304745) 1 NC_008767.1 transposase for IS1106A3 304745 4674940 NMC0299 Neisseria meningitidis FAM18 transposase for IS1106A3 YP_974415.1 303741 R 272831 CDS YP_974416.1 121634171 4674935 complement(306449..307195) 1 NC_008767.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 307195 fabG 4674935 fabG Neisseria meningitidis FAM18 3-ketoacyl-ACP reductase YP_974416.1 306449 R 272831 CDS YP_974417.1 121634172 4675885 complement(307257..308822) 1 NC_008767.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 308822 guaA 4675885 guaA Neisseria meningitidis FAM18 GMP synthase YP_974417.1 307257 R 272831 CDS YP_974418.1 121634173 4676513 complement(308922..310979) 1 NC_008767.1 ABC transporter ATP-binding protein 310979 4676513 NMC0304 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_974418.1 308922 R 272831 CDS YP_974419.1 121634174 4674937 complement(310925..311851) 1 NC_008767.1 malonyl CoA-ACP transacylase 311851 fabD 4674937 fabD Neisseria meningitidis FAM18 malonyl CoA-ACP transacylase YP_974419.1 310925 R 272831 CDS YP_974420.1 121634175 4675876 complement(311945..312352) 1 NC_008767.1 hypothetical protein 312352 4675876 NMC0306 Neisseria meningitidis FAM18 hypothetical protein YP_974420.1 311945 R 272831 CDS YP_974421.1 121634176 4674933 complement(312399..313361) 1 NC_008767.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 313361 fabH 4674933 fabH Neisseria meningitidis FAM18 3-oxoacyl-ACP synthase YP_974421.1 312399 R 272831 CDS YP_974422.1 121634177 4675886 complement(313611..314036) 1 NC_008767.1 hypothetical protein 314036 4675886 NMC0308 Neisseria meningitidis FAM18 hypothetical protein YP_974422.1 313611 R 272831 CDS YP_974423.1 121634178 4674934 complement(314054..314305) 1 NC_008767.1 hypothetical protein 314305 4674934 NMC0309 Neisseria meningitidis FAM18 hypothetical protein YP_974423.1 314054 R 272831 CDS YP_974424.1 121634179 4674932 complement(314441..315496) 1 NC_008767.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 315496 plsX 4674932 plsX Neisseria meningitidis FAM18 glycerol-3-phosphate acyltransferase PlsX YP_974424.1 314441 R 272831 CDS YP_974425.1 121634180 4676107 complement(315584..316111) 1 NC_008767.1 hypothetical protein 316111 4676107 NMC0311 Neisseria meningitidis FAM18 hypothetical protein YP_974425.1 315584 R 272831 CDS YP_974426.1 121634181 4674928 complement(316286..316465) 1 NC_008767.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 316465 rpmF 4674928 rpmF Neisseria meningitidis FAM18 50S ribosomal protein L32 YP_974426.1 316286 R 272831 CDS YP_974427.1 121634182 4675431 complement(316499..317002) 1 NC_008767.1 hypothetical protein 317002 4675431 NMC0313 Neisseria meningitidis FAM18 hypothetical protein YP_974427.1 316499 R 272831 CDS YP_974428.1 121634183 4674931 317150..317740 1 NC_008767.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 317740 4674931 NMC0314 Neisseria meningitidis FAM18 Maf-like protein YP_974428.1 317150 D 272831 CDS YP_974429.1 121634184 4674924 317787..318512 1 NC_008767.1 hypothetical protein 318512 4674924 NMC0315 Neisseria meningitidis FAM18 hypothetical protein YP_974429.1 317787 D 272831 CDS YP_974430.1 121634185 4674920 complement(318593..320230) 1 NC_008767.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 320230 4674920 NMC0316 Neisseria meningitidis FAM18 inner membrane protein translocase component YidC YP_974430.1 318593 R 272831 CDS YP_974431.1 121634186 4674921 complement(320402..320623) 1 NC_008767.1 hypothetical protein 320623 4674921 NMC0317 Neisseria meningitidis FAM18 hypothetical protein YP_974431.1 320402 R 272831 CDS YP_974432.1 121634187 4674922 complement(320688..321053) 1 NC_008767.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 321053 rnpA 4674922 rnpA Neisseria meningitidis FAM18 ribonuclease P YP_974432.1 320688 R 272831 CDS YP_974433.1 121634188 4675576 complement(321056..321190) 1 NC_008767.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 321190 rpmH 4675576 rpmH Neisseria meningitidis FAM18 50S ribosomal protein L34 YP_974433.1 321056 R 272831 CDS YP_974434.1 121634189 4675295 321483..323039 1 NC_008767.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 323039 dnaA 4675295 dnaA Neisseria meningitidis FAM18 chromosome replication initiator DnaA YP_974434.1 321483 D 272831 CDS YP_974435.1 121634190 4675939 323119..324222 1 NC_008767.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 324222 dnaN 4675939 dnaN Neisseria meningitidis FAM18 DNA polymerase III subunit beta YP_974435.1 323119 D 272831 CDS YP_974436.1 121634191 4675925 complement(324485..326635) 1 NC_008767.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 326635 ppk 4675925 ppk Neisseria meningitidis FAM18 polyphosphate kinase YP_974436.1 324485 R 272831 CDS YP_974437.1 121634192 4676078 complement(326711..327154) 1 NC_008767.1 hypothetical protein 327154 4676078 NMC0324 Neisseria meningitidis FAM18 hypothetical protein YP_974437.1 326711 R 272831 CDS YP_974438.1 121634193 4674923 complement(327161..327676) 1 NC_008767.1 lipoprotein 327676 mlp 4674923 mlp Neisseria meningitidis FAM18 lipoprotein YP_974438.1 327161 R 272831 CDS YP_974439.1 121634194 4676288 327943..330573 1 NC_008767.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 330573 leuS 4676288 leuS Neisseria meningitidis FAM18 leucyl-tRNA synthetase YP_974439.1 327943 D 272831 CDS YP_974440.1 121634195 4676230 330811..331623 1 NC_008767.1 DNA adenine methylase 331623 4676230 NMC0327 Neisseria meningitidis FAM18 DNA adenine methylase YP_974440.1 330811 D 272831 CDS YP_974441.1 121634196 4674917 331616..332425 1 NC_008767.1 modification methylase DpnIIB 332425 4674917 NMC0328 Neisseria meningitidis FAM18 modification methylase DpnIIB YP_974441.1 331616 D 272831 CDS YP_974442.1 121634197 4674918 332422..332976 1 NC_008767.1 hypothetical protein 332976 4674918 NMC0329 Neisseria meningitidis FAM18 hypothetical protein YP_974442.1 332422 D 272831 CDS YP_974443.1 121634198 4674908 complement(333746..334057) 1 NC_008767.1 DNA-binding protein 334057 4674908 NMC0331 Neisseria meningitidis FAM18 DNA-binding protein YP_974443.1 333746 R 272831 CDS YP_974444.1 121634199 4674914 complement(334054..334395) 1 NC_008767.1 hypothetical protein 334395 4674914 NMC0332 Neisseria meningitidis FAM18 hypothetical protein YP_974444.1 334054 R 272831 CDS YP_974445.1 121634200 4674911 complement(335322..335672) 1 NC_008767.1 preprotein translocase subunit SecG 335672 secG 4674911 secG Neisseria meningitidis FAM18 preprotein translocase subunit SecG YP_974445.1 335322 R 272831 CDS YP_974446.1 121634201 4675094 complement(335679..336452) 1 NC_008767.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 336452 tpiA 4675094 tpiA Neisseria meningitidis FAM18 triosephosphate isomerase YP_974446.1 335679 R 272831 CDS YP_974447.1 121634202 4674846 336612..337139 1 NC_008767.1 hypothetical protein 337139 4674846 NMC0335 Neisseria meningitidis FAM18 hypothetical protein YP_974447.1 336612 D 272831 CDS YP_974448.1 121634203 4674905 337241..337897 1 NC_008767.1 protein-L-isoaspartate O-methyltransferase 337897 4674905 NMC0336 Neisseria meningitidis FAM18 protein-L-isoaspartate O-methyltransferase YP_974448.1 337241 D 272831 CDS YP_974449.1 121634204 4674907 337977..338300 1 NC_008767.1 hypothetical protein 338300 4674907 NMC0337 Neisseria meningitidis FAM18 hypothetical protein YP_974449.1 337977 D 272831 CDS YP_974450.1 121634205 4674909 complement(338717..340894) 1 NC_008767.1 ferric siderophore receptor protein 340894 4674909 NMC0338 Neisseria meningitidis FAM18 ferric siderophore receptor protein YP_974450.1 338717 R 272831 CDS YP_974451.1 121634206 4674904 complement(341008..341331) 1 NC_008767.1 hypothetical protein 341331 4674904 NMC0339 Neisseria meningitidis FAM18 hypothetical protein YP_974451.1 341008 R 272831 CDS YP_974452.1 121634207 4674902 complement(342383..343348) 1 NC_008767.1 ferric enterobactin transporter binding protein 343348 fetB2 4674902 fetB2 Neisseria meningitidis FAM18 ferric enterobactin transporter binding protein YP_974452.1 342383 R 272831 CDS YP_974453.1 121634208 4676589 343584..344540 1 NC_008767.1 AraC family transcriptional regulator 344540 4676589 NMC0341 Neisseria meningitidis FAM18 AraC family transcriptional regulator YP_974453.1 343584 D 272831 CDS YP_974454.1 121634209 4674903 complement(344654..346669) 1 NC_008767.1 prolyl endopeptidase 346669 4674903 NMC0342 Neisseria meningitidis FAM18 prolyl endopeptidase YP_974454.1 344654 R 272831 CDS YP_974455.1 121634210 4674898 complement(346765..348075) 1 NC_008767.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 348075 argA 4674898 argA Neisseria meningitidis FAM18 N-acetylglutamate synthase YP_974455.1 346765 R 272831 CDS YP_974456.1 121634211 4676424 complement(348072..348506) 1 NC_008767.1 hypothetical protein 348506 4676424 NMC0344 Neisseria meningitidis FAM18 hypothetical protein YP_974456.1 348072 R 272831 CDS YP_974457.1 121634212 4674900 complement(348580..349221) 1 NC_008767.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 349221 pyrE 4674900 pyrE Neisseria meningitidis FAM18 orotate phosphoribosyltransferase YP_974457.1 348580 R 272831 CDS YP_974458.1 121634213 4675775 complement(349283..350017) 1 NC_008767.1 hypothetical protein 350017 4675775 NMC0346 Neisseria meningitidis FAM18 hypothetical protein YP_974458.1 349283 R 272831 CDS YP_974459.1 121634214 4674901 complement(350011..350451) 1 NC_008767.1 acetyltransferase 350451 4674901 NMC0347 Neisseria meningitidis FAM18 acetyltransferase YP_974459.1 350011 R 272831 CDS YP_974460.1 121634215 4674897 complement(350448..351125) 1 NC_008767.1 hypothetical protein 351125 4674897 NMC0348 Neisseria meningitidis FAM18 hypothetical protein YP_974460.1 350448 R 272831 CDS YP_974461.1 121634216 4674891 complement(351263..352102) 1 NC_008767.1 lipoprotein 352102 4674891 NMC0349 Neisseria meningitidis FAM18 lipoprotein YP_974461.1 351263 R 272831 CDS YP_974462.1 121634217 4674894 complement(352242..353306) 1 NC_008767.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 353306 fba 4674894 fba Neisseria meningitidis FAM18 fructose-1,6-bisphosphate aldolase YP_974462.1 352242 R 272831 CDS YP_974463.1 121634218 4675276 353500..354417 1 NC_008767.1 integrase/recombinase 354417 xerC 4675276 xerC Neisseria meningitidis FAM18 integrase/recombinase YP_974463.1 353500 D 272831 CDS YP_974464.1 121634219 4676538 354502..356415 1 NC_008767.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 356415 dxs 4676538 dxs Neisseria meningitidis FAM18 1-deoxy-D-xylulose-5-phosphate synthase YP_974464.1 354502 D 272831 CDS YP_974465.1 121634220 4675917 complement(356500..357828) 1 NC_008767.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 357828 4675917 NMC0353 Neisseria meningitidis FAM18 (dimethylallyl)adenosine tRNA methylthiotransferase YP_974465.1 356500 R 272831 CDS YP_974466.1 121634221 4674895 358611..359894 1 NC_008767.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 359894 hemL 4674895 hemL Neisseria meningitidis FAM18 glutamate-1-semialdehyde aminotransferase YP_974466.1 358611 D 272831 CDS YP_974467.1 121634222 4676497 complement(360300..360863) 1 NC_008767.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 360863 orn 4676497 orn Neisseria meningitidis FAM18 oligoribonuclease YP_974467.1 360300 R 272831 CDS YP_974468.1 121634223 4676120 complement(360881..361768) 1 NC_008767.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 361768 prmA 4676120 prmA Neisseria meningitidis FAM18 50S ribosomal protein L11 methyltransferase YP_974468.1 360881 R 272831 CDS YP_974469.1 121634224 4676054 complement(362029..363390) 1 NC_008767.1 acetyl-CoA carboxylase biotin carboxylase component 363390 accC 4676054 accC Neisseria meningitidis FAM18 acetyl-CoA carboxylase biotin carboxylase component YP_974469.1 362029 R 272831 CDS YP_974470.1 121634225 4676205 complement(363502..363957) 1 NC_008767.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 363957 accB 4676205 accB Neisseria meningitidis FAM18 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_974470.1 363502 R 272831 CDS YP_974471.1 121634226 4676204 364274..365353 1 NC_008767.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 365353 queA 4676204 queA Neisseria meningitidis FAM18 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_974471.1 364274 D 272831 CDS YP_974472.1 121634227 4675771 complement(365724..366302) 1 NC_008767.1 hypothetical protein 366302 4675771 NMC0361 Neisseria meningitidis FAM18 hypothetical protein YP_974472.1 365724 R 272831 CDS YP_974473.1 121634228 4674896 366541..367440 1 NC_008767.1 LysR family transcriptional regulator 367440 4674896 NMC0362 Neisseria meningitidis FAM18 LysR family transcriptional regulator YP_974473.1 366541 D 272831 CDS YP_974474.1 121634229 4674892 complement(367667..370882) 1 NC_008767.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 370882 carB 4674892 carB Neisseria meningitidis FAM18 carbamoyl phosphate synthase large subunit YP_974474.1 367667 R 272831 CDS YP_974475.1 121634230 4676541 complement(370889..371437) 1 NC_008767.1 hypothetical protein 371437 4676541 NMC0364 Neisseria meningitidis FAM18 hypothetical protein YP_974475.1 370889 R 272831 CDS YP_974476.1 121634231 4674890 complement(371440..372003) 1 NC_008767.1 hypothetical protein 372003 4674890 NMC0365 Neisseria meningitidis FAM18 hypothetical protein YP_974476.1 371440 R 272831 CDS YP_974477.1 121634232 4674889 complement(372581..372970) 1 NC_008767.1 hypothetical protein 372970 4674889 NMC0366 Neisseria meningitidis FAM18 hypothetical protein YP_974477.1 372581 R 272831 CDS YP_974478.1 121634233 4674886 complement(372967..373227) 1 NC_008767.1 hypothetical protein 373227 4674886 NMC0367 Neisseria meningitidis FAM18 hypothetical protein YP_974478.1 372967 R 272831 CDS YP_974479.1 121634234 4674887 complement(373301..373447) 1 NC_008767.1 hypothetical protein 373447 4674887 NMC0368 Neisseria meningitidis FAM18 hypothetical protein YP_974479.1 373301 R 272831 CDS YP_974480.1 121634235 4674888 complement(373550..373687) 1 NC_008767.1 hypothetical protein 373687 4674888 NMC0369 Neisseria meningitidis FAM18 hypothetical protein YP_974480.1 373550 R 272831 CDS YP_974481.1 121634236 4674883 complement(373733..374866) 1 NC_008767.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 374866 carA 4674883 carA Neisseria meningitidis FAM18 carbamoyl phosphate synthase small subunit YP_974481.1 373733 R 272831 CDS YP_974482.1 121634237 4676525 complement(376847..379963) 1 NC_008767.1 pilus-associated protein 379963 pilC1 4676525 pilC1 Neisseria meningitidis FAM18 pilus-associated protein YP_974482.1 376847 R 272831 CDS YP_974483.1 121634238 4676103 complement(380917..381996) 1 NC_008767.1 hypothetical protein 381996 4676103 NMC0372 Neisseria meningitidis FAM18 hypothetical protein YP_974483.1 380917 R 272831 CDS YP_974484.1 121634239 4674885 382354..382875 1 NC_008767.1 periplasmic thioredoxin 382875 4674885 NMC0373 Neisseria meningitidis FAM18 periplasmic thioredoxin YP_974484.1 382354 D 272831 CDS YP_974485.1 121634240 4674875 383218..383658 1 NC_008767.1 MarR family transcriptional regulator 383658 4674875 NMC0374 Neisseria meningitidis FAM18 MarR family transcriptional regulator YP_974485.1 383218 D 272831 CDS YP_974486.1 121634241 4674876 383773..384273 1 NC_008767.1 NADH:FMN oxidoreductase 384273 4674876 NMC0375 Neisseria meningitidis FAM18 NADH:FMN oxidoreductase YP_974486.1 383773 D 272831 CDS YP_974487.1 121634242 4674877 384289..384984 1 NC_008767.1 sugar-phosphate nucleotidyl transferase 384984 4674877 NMC0376 Neisseria meningitidis FAM18 sugar-phosphate nucleotidyl transferase YP_974487.1 384289 D 272831 CDS YP_974488.1 121634243 4674874 complement(385215..385646) 1 NC_008767.1 hypothetical protein 385646 4674874 NMC0377 Neisseria meningitidis FAM18 hypothetical protein YP_974488.1 385215 R 272831 CDS YP_974489.1 121634244 4674871 385821..387497 1 NC_008767.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 387497 fhs 4674871 fhs Neisseria meningitidis FAM18 formate--tetrahydrofolate ligase YP_974489.1 385821 D 272831 CDS YP_974490.1 121634245 4676677 387611..388702 1 NC_008767.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 388702 4676677 NMC0379 Neisseria meningitidis FAM18 GTP-dependent nucleic acid-binding protein EngD YP_974490.1 387611 D 272831 CDS YP_974491.1 121634246 4674872 join(389077..389259,389262..390959) 1 NC_008767.1 lipopolysaccharide modification acyltransferase 390959 4674872 NMC0380 Neisseria meningitidis FAM18 lipopolysaccharide modification acyltransferase YP_974491.1 389077 D 272831 CDS YP_974492.1 121634247 4674870 391022..392317 1 NC_008767.1 tyrosyl-tRNA synthetase 392317 tyrS 4674870 tyrS Neisseria meningitidis FAM18 tyrosyl-tRNA synthetase YP_974492.1 391022 D 272831 CDS YP_974493.1 121634248 4676483 392808..393764 1 NC_008767.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 393764 ribF 4676483 ribF Neisseria meningitidis FAM18 bifunctional riboflavin kinase/FMN adenylyltransferase YP_974493.1 392808 D 272831 CDS YP_974494.1 121634249 4675586 393905..396694 1 NC_008767.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 396694 ileS 4675586 ileS Neisseria meningitidis FAM18 isoleucyl-tRNA synthetase YP_974494.1 393905 D 272831 CDS YP_974495.1 121634250 4676440 397998..398495 1 NC_008767.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 398495 lspA 4676440 lspA Neisseria meningitidis FAM18 lipoprotein signal peptidase YP_974495.1 397998 D 272831 CDS YP_974496.1 121634251 4676329 398524..399492 1 NC_008767.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 399492 ispH 4676329 ispH Neisseria meningitidis FAM18 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_974496.1 398524 D 272831 CDS YP_974497.1 121634252 4676331 complement(399579..400238) 1 NC_008767.1 phosphatase 400238 4676331 NMC0386 Neisseria meningitidis FAM18 phosphatase YP_974497.1 399579 R 272831 CDS YP_974498.1 121634253 4674869 400386..402554 1 NC_008767.1 TonB-dependent receptor 402554 4674869 NMC0387 Neisseria meningitidis FAM18 TonB-dependent receptor YP_974498.1 400386 D 272831 CDS YP_974499.1 121634254 4674861 402624..403556 1 NC_008767.1 esterase 403556 4674861 NMC0388 Neisseria meningitidis FAM18 esterase YP_974499.1 402624 D 272831 CDS YP_974500.1 121634255 4674864 complement(403990..407424) 1 NC_008767.1 DNA polymerase III subunit alpha 407424 dnaE 4674864 dnaE Neisseria meningitidis FAM18 DNA polymerase III subunit alpha YP_974500.1 403990 R 272831 CDS YP_974501.1 121634256 4675957 407587..407823 1 NC_008767.1 hypothetical protein 407823 4675957 NMC0390 Neisseria meningitidis FAM18 hypothetical protein YP_974501.1 407587 D 272831 CDS YP_974502.1 121634257 4674868 407801..408004 1 NC_008767.1 hypothetical protein 408004 4674868 NMC0392 Neisseria meningitidis FAM18 hypothetical protein YP_974502.1 407801 D 272831 CDS YP_974503.1 121634258 4674860 408109..408510 1 NC_008767.1 hypothetical protein 408510 4674860 NMC0393 Neisseria meningitidis FAM18 hypothetical protein YP_974503.1 408109 D 272831 CDS YP_974504.1 121634259 4674855 408820..409656 1 NC_008767.1 hypothetical protein 409656 4674855 NMC0394 Neisseria meningitidis FAM18 hypothetical protein YP_974504.1 408820 D 272831 CDS YP_974505.1 121634260 4674858 complement(409708..411000) 1 NC_008767.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 411000 avtA 4674858 avtA Neisseria meningitidis FAM18 valine--pyruvate transaminase YP_974505.1 409708 R 272831 CDS YP_974506.1 121634261 4676676 complement(411056..412966) 1 NC_008767.1 pilin glycosylation protein 412966 pglD 4676676 pglD Neisseria meningitidis FAM18 pilin glycosylation protein YP_974506.1 411056 R 272831 CDS YP_974507.1 121634262 4676147 complement(413014..414189) 1 NC_008767.1 pilin glycosylation protein 414189 pglC 4676147 pglC Neisseria meningitidis FAM18 pilin glycosylation protein YP_974507.1 413014 R 272831 CDS YP_974508.1 121634263 4676146 complement(414660..415346) 1 NC_008767.1 hydrolase, haloacid dehalogenase-like hydrolase 415346 4676146 NMC0398 Neisseria meningitidis FAM18 hydrolase, haloacid dehalogenase-like hydrolase YP_974508.1 414660 R 272831 CDS YP_974509.1 121634264 4674857 complement(join(415333..416301,416300..416911)) 1 NC_008767.1 protein Pglb2 416911 4674857 NMC0399 Neisseria meningitidis FAM18 protein Pglb2 YP_974509.1 415333 R 272831 CDS YP_974510.1 121634265 4674859 complement(416904..418076) 1 NC_008767.1 hypothetical protein 418076 4674859 NMC0400 Neisseria meningitidis FAM18 hypothetical protein YP_974510.1 416904 R 272831 CDS YP_974511.1 121634266 4674854 complement(join(418090..418671,418673..419173)) 1 NC_008767.1 hypothetical protein 419173 4674854 NMC0401 Neisseria meningitidis FAM18 hypothetical protein YP_974511.1 418090 R 272831 CDS YP_974512.1 121634267 4674856 complement(419170..420597) 1 NC_008767.1 lipopolysaccharide biosynthesis translocase 420597 4674856 NMC0402 Neisseria meningitidis FAM18 lipopolysaccharide biosynthesis translocase YP_974512.1 419170 R 272831 CDS YP_974513.1 121634268 4674849 complement(420792..421901) 1 NC_008767.1 diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase 421901 ribD 4674849 ribD Neisseria meningitidis FAM18 diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase YP_974513.1 420792 R 272831 CDS YP_974514.1 121634269 4675539 complement(421934..422398) 1 NC_008767.1 transcriptional regulator NrdR 422398 nrdR 4675539 nrdR Neisseria meningitidis FAM18 transcriptional regulator NrdR YP_974514.1 421934 R 272831 CDS YP_974515.1 121634270 4674853 complement(422427..423269) 1 NC_008767.1 hypothetical protein 423269 4674853 NMC0405 Neisseria meningitidis FAM18 hypothetical protein YP_974515.1 422427 R 272831 CDS YP_974516.1 121634271 4674848 complement(424559..425638) 1 NC_008767.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 425638 aroB 4674848 aroB Neisseria meningitidis FAM18 3-dehydroquinate synthase YP_974516.1 424559 R 272831 CDS YP_974517.1 121634272 4675592 complement(425718..426233) 1 NC_008767.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 426233 aroK 4675592 aroK Neisseria meningitidis FAM18 shikimate kinase YP_974517.1 425718 R 272831 CDS YP_974518.1 121634273 4675619 complement(join(427192..428472,428474..428962)) 1 NC_008767.1 pilus secretin 428962 pilQ 4675619 pilQ Neisseria meningitidis FAM18 pilus secretin YP_974518.1 427192 R 272831 CDS YP_974519.1 121634274 4676098 complement(428981..429526) 1 NC_008767.1 pilus assembly protein 429526 pilP 4676098 pilP Neisseria meningitidis FAM18 pilus assembly protein YP_974519.1 428981 R 272831 CDS YP_974520.1 121634275 4676097 complement(429544..430191) 1 NC_008767.1 pilus assembly protein 430191 pilO 4676097 pilO Neisseria meningitidis FAM18 pilus assembly protein YP_974520.1 429544 R 272831 CDS YP_974521.1 121634276 4676015 complement(430192..430791) 1 NC_008767.1 pilus assembly protein 430791 pilN 4676015 pilN Neisseria meningitidis FAM18 pilus assembly protein YP_974521.1 430192 R 272831 CDS YP_974522.1 121634277 4676014 complement(430794..431909) 1 NC_008767.1 pilus assembly protein 431909 pilM 4676014 pilM Neisseria meningitidis FAM18 pilus assembly protein YP_974522.1 430794 R 272831 CDS YP_974523.1 121634278 4676110 432061..434457 1 NC_008767.1 penicillin-binding protein 1 434457 ponA 4676110 ponA Neisseria meningitidis FAM18 penicillin-binding protein 1 YP_974523.1 432061 D 272831 CDS YP_974524.1 121634279 4676093 complement(434578..435207) 1 NC_008767.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 435207 engB 4676093 engB Neisseria meningitidis FAM18 ribosome biogenesis GTP-binding protein YsxC YP_974524.1 434578 R 272831 CDS YP_974525.1 121634280 4674850 435413..436036 1 NC_008767.1 cytochrome C 436036 cyc 4674850 cyc Neisseria meningitidis FAM18 cytochrome C YP_974525.1 435413 D 272831 CDS YP_974526.1 121634281 4675812 436250..438265 1 NC_008767.1 hypothetical protein 438265 4675812 NMC0417 Neisseria meningitidis FAM18 hypothetical protein YP_974526.1 436250 D 272831 CDS YP_974527.1 121634282 4674842 438258..439445 1 NC_008767.1 hypothetical protein 439445 4674842 NMC0418 Neisseria meningitidis FAM18 hypothetical protein YP_974527.1 438258 D 272831 CDS YP_974528.1 121634283 4674844 439561..440625 1 NC_008767.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 440625 gcp 4674844 gcp Neisseria meningitidis FAM18 DNA-binding/iron metalloprotein/AP endonuclease YP_974528.1 439561 D 272831 CDS YP_974529.1 121634284 4676596 complement(440669..441565) 1 NC_008767.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 441565 4676596 NMC0421 Neisseria meningitidis FAM18 lipid A biosynthesis lauroyl acyltransferase YP_974529.1 440669 R 272831 CDS YP_974530.1 121634285 4674837 441911..443080 1 NC_008767.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 443080 metK 4674837 metK Neisseria meningitidis FAM18 S-adenosylmethionine synthetase YP_974530.1 441911 D 272831 CDS YP_974531.1 121634286 4676319 join(443572..444030,444032..444223) 1 NC_008767.1 insertion element IS1016 transposase 444223 4676319 NMC0423 Neisseria meningitidis FAM18 insertion element IS1016 transposase YP_974531.1 443572 D 272831 CDS YP_974532.1 121634287 4674841 complement(444299..445708) 1 NC_008767.1 peptidase 445708 4674841 NMC0425 Neisseria meningitidis FAM18 peptidase YP_974532.1 444299 R 272831 CDS YP_974533.1 121634288 4674836 445873..446439 1 NC_008767.1 oxidoreductase 446439 4674836 NMC0426 Neisseria meningitidis FAM18 oxidoreductase YP_974533.1 445873 D 272831 CDS YP_974534.1 121634289 4674835 447005..448321 1 NC_008767.1 transmembrane transport protein 448321 4674835 NMC0427 Neisseria meningitidis FAM18 transmembrane transport protein YP_974534.1 447005 D 272831 CDS YP_974535.1 121634290 4674833 448529..448675 1 NC_008767.1 two-component system response regulator 448675 4674833 NMC0428 Neisseria meningitidis FAM18 two-component system response regulator YP_974535.1 448529 D 272831 CDS YP_974536.1 121634291 4674826 448715..449965 1 NC_008767.1 two-component system sensor kinase 449965 4674826 NMC0429 Neisseria meningitidis FAM18 two-component system sensor kinase YP_974536.1 448715 D 272831 CDS YP_974537.1 121634292 4674825 complement(449999..451492) 1 NC_008767.1 hypothetical protein 451492 4674825 NMC0430 Neisseria meningitidis FAM18 hypothetical protein YP_974537.1 449999 R 272831 CDS YP_974538.1 121634293 4674824 451681..451962 1 NC_008767.1 glutaredoxin 451962 4674824 NMC0431 Neisseria meningitidis FAM18 glutaredoxin YP_974538.1 451681 D 272831 CDS YP_974539.1 121634294 4674823 451983..452426 1 NC_008767.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 452426 secB 4674823 secB Neisseria meningitidis FAM18 preprotein translocase subunit SecB YP_974539.1 451983 D 272831 CDS YP_974540.1 121634295 4675100 452512..454554 1 NC_008767.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 454554 recG 4675100 recG Neisseria meningitidis FAM18 ATP-dependent DNA helicase RecG YP_974540.1 452512 D 272831 CDS YP_974541.1 121634296 4675758 complement(455710..456753) 1 NC_008767.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 456753 argC 4675758 argC Neisseria meningitidis FAM18 N-acetyl-gamma-glutamyl-phosphate reductase YP_974541.1 455710 R 272831 CDS YP_974542.1 121634297 4676426 complement(456750..457031) 1 NC_008767.1 hypothetical protein 457031 4676426 NMC0435 Neisseria meningitidis FAM18 hypothetical protein YP_974542.1 456750 R 272831 CDS YP_974543.1 121634298 4674819 join(457285..457335,457337..458440) 1 NC_008767.1 hypothetical protein 458440 4674819 NMC0436 Neisseria meningitidis FAM18 hypothetical protein YP_974543.1 457285 D 272831 CDS YP_974544.1 121634299 4674816 458437..458676 1 NC_008767.1 lipoprotein 458676 4674816 NMC0437 Neisseria meningitidis FAM18 lipoprotein YP_974544.1 458437 D 272831 CDS YP_974545.1 121634300 4674815 458669..459022 1 NC_008767.1 hypothetical protein 459022 4674815 NMC0438 Neisseria meningitidis FAM18 hypothetical protein YP_974545.1 458669 D 272831 CDS YP_974546.1 121634301 4674812 join(459083..459610,459613..459861) 1 NC_008767.1 secretion protein 459861 4674812 NMC0439 Neisseria meningitidis FAM18 secretion protein YP_974546.1 459083 D 272831 CDS YP_974547.1 121634302 4674811 460170..460472 1 NC_008767.1 hypothetical protein 460472 4674811 NMC0440 Neisseria meningitidis FAM18 hypothetical protein YP_974547.1 460170 D 272831 CDS YP_974548.1 121634303 4674810 460487..460657 1 NC_008767.1 hypothetical protein 460657 4674810 NMC0441 Neisseria meningitidis FAM18 hypothetical protein YP_974548.1 460487 D 272831 CDS YP_974549.1 121634304 4674809 461056..462798 1 NC_008767.1 hemolysin activator 462798 4674809 NMC0443 Neisseria meningitidis FAM18 hemolysin activator YP_974549.1 461056 D 272831 CDS YP_974550.1 121634305 4674808 462907..468987 1 NC_008767.1 hemagglutinin 468987 4674808 NMC0444 Neisseria meningitidis FAM18 hemagglutinin YP_974550.1 462907 D 272831 CDS YP_974551.1 121634306 4674807 468994..469503 1 NC_008767.1 hypothetical protein 469503 4674807 NMC0445 Neisseria meningitidis FAM18 hypothetical protein YP_974551.1 468994 D 272831 CDS YP_974552.1 121634307 4674805 471672..472046 1 NC_008767.1 hypothetical protein 472046 4674805 NMC0447 Neisseria meningitidis FAM18 hypothetical protein YP_974552.1 471672 D 272831 CDS YP_974553.1 121634308 4674804 472359..473861 1 NC_008767.1 hemagglutinin/hemolysin-like protein 473861 rte5 4674804 rte5 Neisseria meningitidis FAM18 hemagglutinin/hemolysin-like protein YP_974553.1 472359 D 272831 CDS YP_974554.1 121634309 4675124 473880..474143 1 NC_008767.1 hypothetical protein 474143 4675124 NMC0449 Neisseria meningitidis FAM18 hypothetical protein YP_974554.1 473880 D 272831 CDS YP_974555.1 121634310 4674803 474250..476637 1 NC_008767.1 hemagglutinin/hemolysin-like protein 476637 4674803 NMC0450 Neisseria meningitidis FAM18 hemagglutinin/hemolysin-like protein YP_974555.1 474250 D 272831 CDS YP_974556.1 121634311 4674802 476642..477025 1 NC_008767.1 hypothetical protein 477025 4674802 NMC0451 Neisseria meningitidis FAM18 hypothetical protein YP_974556.1 476642 D 272831 CDS YP_974557.1 121634312 4674801 477275..479776 1 NC_008767.1 hemagglutinin 479776 4674801 NMC0452 Neisseria meningitidis FAM18 hemagglutinin YP_974557.1 477275 D 272831 CDS YP_974558.1 121634313 4674800 479773..480261 1 NC_008767.1 hypothetical protein 480261 4674800 NMC0453 Neisseria meningitidis FAM18 hypothetical protein YP_974558.1 479773 D 272831 CDS YP_974559.1 121634314 4674799 480449..480721 1 NC_008767.1 hypothetical protein 480721 4674799 NMC0454 Neisseria meningitidis FAM18 hypothetical protein YP_974559.1 480449 D 272831 CDS YP_974560.1 121634315 4674796 480925..481893 1 NC_008767.1 hypothetical protein 481893 4674796 NMC0456 Neisseria meningitidis FAM18 hypothetical protein YP_974560.1 480925 D 272831 CDS YP_974561.1 121634316 4674795 481896..482831 1 NC_008767.1 hypothetical protein 482831 4674795 NMC0457 Neisseria meningitidis FAM18 hypothetical protein YP_974561.1 481896 D 272831 CDS YP_974562.1 121634317 4674793 483601..483879 1 NC_008767.1 hypothetical protein 483879 4674793 NMC0458 Neisseria meningitidis FAM18 hypothetical protein YP_974562.1 483601 D 272831 CDS YP_974563.1 121634318 4674791 484162..484620 1 NC_008767.1 hypothetical protein 484620 4674791 NMC0459 Neisseria meningitidis FAM18 hypothetical protein YP_974563.1 484162 D 272831 CDS YP_974564.1 121634319 4674790 complement(485133..486359) 1 NC_008767.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; this protein contains a C-terminal extension of unknown function; ribonuclease BN/unknown domain fusion protein 486359 rbn 4674790 rbn Neisseria meningitidis FAM18 ribonuclease BN/unknown domain fusion protein YP_974564.1 485133 R 272831 CDS YP_974565.1 121634320 4674789 486904..487563 1 NC_008767.1 hypothetical protein 487563 4674789 NMC0464 Neisseria meningitidis FAM18 hypothetical protein YP_974565.1 486904 D 272831 CDS YP_974566.1 121634321 4674788 487591..488106 1 NC_008767.1 hypothetical protein 488106 4674788 NMC0465 Neisseria meningitidis FAM18 hypothetical protein YP_974566.1 487591 D 272831 CDS YP_974567.1 121634322 4674785 488113..488535 1 NC_008767.1 hypothetical protein 488535 4674785 NMC0466 Neisseria meningitidis FAM18 hypothetical protein YP_974567.1 488113 D 272831 CDS YP_974568.1 121634323 4674784 488804..489175 1 NC_008767.1 hypothetical protein 489175 4674784 NMC0467 Neisseria meningitidis FAM18 hypothetical protein YP_974568.1 488804 D 272831 CDS YP_974569.1 121634324 4674781 489172..489810 1 NC_008767.1 hypothetical protein 489810 4674781 NMC0468 Neisseria meningitidis FAM18 hypothetical protein YP_974569.1 489172 D 272831 CDS YP_974570.1 121634325 4674779 complement(490450..491535) 1 NC_008767.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 491535 4674779 NMC0469 Neisseria meningitidis FAM18 beta-hexosaminidase YP_974570.1 490450 R 272831 CDS YP_974571.1 121634326 4674778 complement(491592..493112) 1 NC_008767.1 hypothetical protein 493112 4674778 NMC0470 Neisseria meningitidis FAM18 hypothetical protein YP_974571.1 491592 R 272831 CDS YP_974572.1 121634327 4674777 complement(493312..494811) 1 NC_008767.1 periplasmic serine protease 494811 4674777 NMC0471 Neisseria meningitidis FAM18 periplasmic serine protease YP_974572.1 493312 R 272831 CDS YP_974573.1 121634328 4674776 complement(494949..495578) 1 NC_008767.1 endonuclease III 495578 nth 4674776 nth Neisseria meningitidis FAM18 endonuclease III YP_974573.1 494949 R 272831 CDS YP_974574.1 121634329 4676211 complement(495624..496052) 1 NC_008767.1 hypothetical protein 496052 4676211 NMC0473 Neisseria meningitidis FAM18 hypothetical protein YP_974574.1 495624 R 272831 CDS YP_974575.1 121634330 4674773 496627..497850 1 NC_008767.1 transmembrane hexose transporter 497850 4674773 NMC0474 Neisseria meningitidis FAM18 transmembrane hexose transporter YP_974575.1 496627 D 272831 CDS YP_974576.1 121634331 4674771 498141..499520 1 NC_008767.1 transmembrane transport protein 499520 4674771 NMC0475 Neisseria meningitidis FAM18 transmembrane transport protein YP_974576.1 498141 D 272831 CDS YP_974577.1 121634332 4674770 complement(499649..500473) 1 NC_008767.1 hypothetical protein 500473 4674770 NMC0476 Neisseria meningitidis FAM18 hypothetical protein YP_974577.1 499649 R 272831 CDS YP_974578.1 121634333 4674769 complement(500475..500990) 1 NC_008767.1 hypothetical protein 500990 4674769 NMC0477 Neisseria meningitidis FAM18 hypothetical protein YP_974578.1 500475 R 272831 CDS YP_974579.1 121634334 4674768 501109..502044 1 NC_008767.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 502044 hemC 4674768 hemC Neisseria meningitidis FAM18 porphobilinogen deaminase YP_974579.1 501109 D 272831 CDS YP_974580.1 121634335 4676351 complement(502447..503640) 1 NC_008767.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 503640 aspC 4676351 aspC Neisseria meningitidis FAM18 aromatic amino acid aminotransferase YP_974580.1 502447 R 272831 CDS YP_974581.1 121634336 4675643 complement(503722..504219) 1 NC_008767.1 hypothetical protein 504219 4675643 NMC0480 Neisseria meningitidis FAM18 hypothetical protein YP_974581.1 503722 R 272831 CDS YP_974582.1 121634337 4674767 504335..504538 1 NC_008767.1 hypothetical protein 504538 4674767 NMC0481 Neisseria meningitidis FAM18 hypothetical protein YP_974582.1 504335 D 272831 CDS YP_974583.1 121634338 4674764 complement(504706..506292) 1 NC_008767.1 transmembrane transport protein 506292 4674764 NMC0482 Neisseria meningitidis FAM18 transmembrane transport protein YP_974583.1 504706 R 272831 CDS YP_974584.1 121634339 4674763 complement(506561..507283) 1 NC_008767.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 507283 4674763 NMC0483 Neisseria meningitidis FAM18 UDP-2,3-diacylglucosamine hydrolase YP_974584.1 506561 R 272831 CDS YP_974585.1 121634340 4674762 507533..511018 1 NC_008767.1 hypothetical protein 511018 4674762 NMC0484 Neisseria meningitidis FAM18 hypothetical protein YP_974585.1 507533 D 272831 CDS YP_974586.1 121634341 4674761 complement(511369..512415) 1 NC_008767.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 512415 adhA 4674761 adhA Neisseria meningitidis FAM18 alcohol dehydrogenase YP_974586.1 511369 R 272831 CDS YP_974587.1 121634342 4675518 complement(512699..513088) 1 NC_008767.1 pilin 513088 4675518 NMC0487 Neisseria meningitidis FAM18 pilin YP_974587.1 512699 R 272831 CDS YP_974588.1 121634343 4674760 513314..514492 1 NC_008767.1 hypothetical protein 514492 4674760 NMC0488 Neisseria meningitidis FAM18 hypothetical protein YP_974588.1 513314 D 272831 CDS YP_974589.1 121634344 4674759 514558..516492 1 NC_008767.1 ABC transporter ATP-binding protein 516492 4674759 NMC0489 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_974589.1 514558 D 272831 CDS YP_974590.1 121634345 4674758 complement(516795..517637) 1 NC_008767.1 thiol:disulfide interchange protein 517637 4674758 NMC0490 Neisseria meningitidis FAM18 thiol:disulfide interchange protein YP_974590.1 516795 R 272831 CDS YP_974591.1 121634346 4674756 517734..519923 1 NC_008767.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 519923 priA 4674756 priA Neisseria meningitidis FAM18 primosome assembly protein PriA YP_974591.1 517734 D 272831 CDS YP_974592.1 121634347 4675970 complement(519970..521082) 1 NC_008767.1 hypothetical protein 521082 4675970 NMC0493 Neisseria meningitidis FAM18 hypothetical protein YP_974592.1 519970 R 272831 CDS YP_974593.1 121634348 4674746 complement(521091..522047) 1 NC_008767.1 transposase 522047 4674746 NMC0494 Neisseria meningitidis FAM18 transposase YP_974593.1 521091 R 272831 CDS YP_974594.1 121634349 4676715 complement(523485..525413) 1 NC_008767.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 525413 dnaK 4676715 dnaK Neisseria meningitidis FAM18 molecular chaperone DnaK YP_974594.1 523485 R 272831 CDS YP_974595.1 121634350 4675944 complement(525621..525893) 1 NC_008767.1 hypothetical protein 525893 4675944 NMC0496 Neisseria meningitidis FAM18 hypothetical protein YP_974595.1 525621 R 272831 CDS YP_974596.1 121634351 4675147 526079..526765 1 NC_008767.1 transcriptional regulator 526765 4675147 NMC0497 Neisseria meningitidis FAM18 transcriptional regulator YP_974596.1 526079 D 272831 CDS YP_974597.1 121634352 4674753 526897..527235 1 NC_008767.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 527235 4674753 NMC0498 Neisseria meningitidis FAM18 iron-sulfur cluster insertion protein ErpA YP_974597.1 526897 D 272831 CDS YP_974598.1 121634353 4674751 527395..527859 1 NC_008767.1 hypothetical protein 527859 4674751 NMC0499 Neisseria meningitidis FAM18 hypothetical protein YP_974598.1 527395 D 272831 CDS YP_974599.1 121634354 4675137 527894..529405 1 NC_008767.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 529405 ubiB 4675137 ubiB Neisseria meningitidis FAM18 ubiquinone biosynthesis protein UbiB YP_974599.1 527894 D 272831 CDS YP_974600.1 121634355 4676711 complement(529762..530580) 1 NC_008767.1 serine acetyltransferase 530580 cysE 4676711 cysE Neisseria meningitidis FAM18 serine acetyltransferase YP_974600.1 529762 R 272831 CDS YP_974601.1 121634356 4675632 530764..531342 1 NC_008767.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 531342 grpE 4675632 grpE Neisseria meningitidis FAM18 heat shock protein GrpE YP_974601.1 530764 D 272831 CDS YP_974602.1 121634357 4676251 complement(531466..531681) 1 NC_008767.1 hypothetical protein 531681 4676251 NMC0503 Neisseria meningitidis FAM18 hypothetical protein YP_974602.1 531466 R 272831 CDS YP_974603.1 121634358 4675151 complement(531707..532783) 1 NC_008767.1 thiamine biosynthesis protein 532783 apbE 4675151 apbE Neisseria meningitidis FAM18 thiamine biosynthesis protein YP_974603.1 531707 R 272831 CDS YP_974604.1 121634359 4676372 complement(532914..534131) 1 NC_008767.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 534131 nqrF 4676372 nqrF Neisseria meningitidis FAM18 Na(+)-translocating NADH-quinone reductase subunit F YP_974604.1 532914 R 272831 CDS YP_974605.1 121634360 4676124 complement(534145..534738) 1 NC_008767.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 534738 nqrE 4676124 nqrE Neisseria meningitidis FAM18 Na(+)-translocating NADH-quinone reductase subunit E YP_974605.1 534145 R 272831 CDS YP_974606.1 121634361 4676217 complement(534742..535368) 1 NC_008767.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 535368 nqrD 4676217 nqrD Neisseria meningitidis FAM18 Na(+)-translocating NADH-quinone reductase subunit D YP_974606.1 534742 R 272831 CDS YP_974607.1 121634362 4676216 complement(535368..536144) 1 NC_008767.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 536144 nqrC 4676216 nqrC Neisseria meningitidis FAM18 Na(+)-translocating NADH-quinone reductase subunit C YP_974607.1 535368 R 272831 CDS YP_974608.1 121634363 4676232 complement(536137..537369) 1 NC_008767.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 537369 nqrB 4676232 nqrB Neisseria meningitidis FAM18 Na(+)-translocating NADH-quinone reductase subunit B YP_974608.1 536137 R 272831 CDS YP_974609.1 121634364 4676231 complement(537372..538715) 1 NC_008767.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 538715 nqrA 4676231 nqrA Neisseria meningitidis FAM18 Na(+)-translocating NADH-quinone reductase subunit A YP_974609.1 537372 R 272831 CDS YP_974610.1 121634365 4676223 complement(539063..540502) 1 NC_008767.1 hypothetical protein 540502 4676223 NMC0512 Neisseria meningitidis FAM18 hypothetical protein YP_974610.1 539063 R 272831 CDS YP_974611.1 121634366 4675155 complement(540842..541201) 1 NC_008767.1 hypothetical protein 541201 4675155 NMC0513 Neisseria meningitidis FAM18 hypothetical protein YP_974611.1 540842 R 272831 CDS YP_974612.1 121634367 4676710 complement(541198..541803) 1 NC_008767.1 hypothetical protein 541803 4676710 NMC0514 Neisseria meningitidis FAM18 hypothetical protein YP_974612.1 541198 R 272831 CDS YP_974613.1 121634368 4674919 complement(541850..542332) 1 NC_008767.1 AsnC family transcriptional regulator 542332 4674919 NMC0515 Neisseria meningitidis FAM18 AsnC family transcriptional regulator YP_974613.1 541850 R 272831 CDS YP_974614.1 121634369 4675213 542838..543944 1 NC_008767.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 543944 gcvT 4675213 gcvT Neisseria meningitidis FAM18 glycine cleavage system aminomethyltransferase T YP_974614.1 542838 D 272831 CDS YP_974615.1 121634370 4676617 544107..544493 1 NC_008767.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 544493 gcvH 4676617 gcvH Neisseria meningitidis FAM18 glycine cleavage system protein H YP_974615.1 544107 D 272831 CDS YP_974616.1 121634371 4676633 544645..545892 1 NC_008767.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 545892 hemA 4676633 hemA Neisseria meningitidis FAM18 glutamyl-tRNA reductase YP_974616.1 544645 D 272831 CDS YP_974617.1 121634372 4676508 546168..546740 1 NC_008767.1 regulatory protein 546740 4676508 NMC0519 Neisseria meningitidis FAM18 regulatory protein YP_974617.1 546168 D 272831 CDS YP_974618.1 121634373 4675182 546743..547828 1 NC_008767.1 hypothetical protein 547828 4675182 NMC0520 Neisseria meningitidis FAM18 hypothetical protein YP_974618.1 546743 D 272831 CDS YP_974619.1 121634374 4676246 547886..548506 1 NC_008767.1 ABC transporter ATP-binding protein 548506 4676246 NMC0521 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_974619.1 547886 D 272831 CDS YP_974620.1 121634375 4675221 548723..549217 1 NC_008767.1 lipoprotein 549217 4675221 NMC0522 Neisseria meningitidis FAM18 lipoprotein YP_974620.1 548723 D 272831 CDS YP_974621.1 121634376 4675222 complement(549351..551012) 1 NC_008767.1 electron transfer flavoprotein-ubiquinone oxidoreductase 551012 4675222 NMC0523 Neisseria meningitidis FAM18 electron transfer flavoprotein-ubiquinone oxidoreductase YP_974621.1 549351 R 272831 CDS YP_974622.1 121634377 4675220 complement(551142..551684) 1 NC_008767.1 peptidase 551684 4675220 NMC0524 Neisseria meningitidis FAM18 peptidase YP_974622.1 551142 R 272831 CDS YP_974623.1 121634378 4675226 complement(552629..553282) 1 NC_008767.1 transposase 553282 4675226 NMC0525 Neisseria meningitidis FAM18 transposase YP_974623.1 552629 R 272831 CDS YP_974624.1 121634379 4675225 553888..554703 1 NC_008767.1 hypothetical protein 554703 4675225 NMC0526 Neisseria meningitidis FAM18 hypothetical protein YP_974624.1 553888 D 272831 CDS YP_974625.1 121634380 4675231 554720..560809 1 NC_008767.1 iron-regulated protein FrpC 560809 frpC 4675231 frpC Neisseria meningitidis FAM18 iron-regulated protein FrpC YP_974625.1 554720 D 272831 CDS YP_974626.1 121634381 4676685 complement(561089..562003) 1 NC_008767.1 periplasmic binding protein 562003 4676685 NMC0528 Neisseria meningitidis FAM18 periplasmic binding protein YP_974626.1 561089 R 272831 CDS YP_974627.1 121634382 4675244 complement(562080..562955) 1 NC_008767.1 ABC-transporter membrane protein 562955 4675244 NMC0529 Neisseria meningitidis FAM18 ABC-transporter membrane protein YP_974627.1 562080 R 272831 CDS YP_974628.1 121634383 4675138 complement(562979..563734) 1 NC_008767.1 ABC transporter ATP-binding protein 563734 4675138 NMC0530 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_974628.1 562979 R 272831 CDS YP_974629.1 121634384 4675173 complement(564026..564391) 1 NC_008767.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 564391 rplS 4675173 rplS Neisseria meningitidis FAM18 50S ribosomal protein L19 YP_974629.1 564026 R 272831 CDS YP_974630.1 121634385 4675382 complement(564407..565156) 1 NC_008767.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 565156 trmD 4675382 trmD Neisseria meningitidis FAM18 tRNA (guanine-N(1)-)-methyltransferase YP_974630.1 564407 R 272831 CDS YP_974631.1 121634386 4674831 complement(565156..565665) 1 NC_008767.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 565665 rimM 4674831 rimM Neisseria meningitidis FAM18 16S rRNA-processing protein RimM YP_974631.1 565156 R 272831 CDS YP_974632.1 121634387 4675587 complement(565681..565926) 1 NC_008767.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 565926 rpsP 4675587 rpsP Neisseria meningitidis FAM18 30S ribosomal protein S16 YP_974632.1 565681 R 272831 CDS YP_974633.1 121634388 4675224 complement(565971..568397) 1 NC_008767.1 hypothetical protein 568397 4675224 NMC0535 Neisseria meningitidis FAM18 hypothetical protein YP_974633.1 565971 R 272831 CDS YP_974634.1 121634389 4675172 complement(568515..569921) 1 NC_008767.1 two-component system sensor kinase 569921 4675172 NMC0536 Neisseria meningitidis FAM18 two-component system sensor kinase YP_974634.1 568515 R 272831 CDS YP_974635.1 121634390 4675248 complement(569934..570611) 1 NC_008767.1 two-component system regulator 570611 4675248 NMC0537 Neisseria meningitidis FAM18 two-component system regulator YP_974635.1 569934 R 272831 CDS YP_974636.1 121634391 4675249 complement(570801..572615) 1 NC_008767.1 hypothetical protein 572615 4675249 NMC0539 Neisseria meningitidis FAM18 hypothetical protein YP_974636.1 570801 R 272831 CDS YP_974637.1 121634392 4675252 complement(572605..572958) 1 NC_008767.1 hypothetical protein 572958 4675252 NMC0540 Neisseria meningitidis FAM18 hypothetical protein YP_974637.1 572605 R 272831 CDS YP_974638.1 121634393 4675245 complement(572967..573575) 1 NC_008767.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 573575 4675245 NMC0541 Neisseria meningitidis FAM18 Maf-like protein YP_974638.1 572967 R 272831 CDS YP_974639.1 121634394 4676044 complement(573628..574398) 1 NC_008767.1 sec-independent protein translocase component 574398 tatC 4676044 tatC Neisseria meningitidis FAM18 sec-independent protein translocase component YP_974639.1 573628 R 272831 CDS YP_974640.1 121634395 4675207 complement(574412..575098) 1 NC_008767.1 sec-independent protein translocase component 575098 4675207 NMC0543 Neisseria meningitidis FAM18 sec-independent protein translocase component YP_974640.1 574412 R 272831 CDS YP_974641.1 121634396 4675162 complement(575352..575675) 1 NC_008767.1 nucleotide-binding protein 575675 4675162 NMC0545 Neisseria meningitidis FAM18 nucleotide-binding protein YP_974641.1 575352 R 272831 CDS YP_974642.1 121634397 4675341 complement(575747..576070) 1 NC_008767.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 576070 hisE 4675341 hisE Neisseria meningitidis FAM18 phosphoribosyl-ATP pyrophosphatase YP_974642.1 575747 R 272831 CDS YP_974643.1 121634398 4676484 complement(576211..577275) 1 NC_008767.1 zinc-binding alcohol dehydrogenase 577275 4676484 NMC0547 Neisseria meningitidis FAM18 zinc-binding alcohol dehydrogenase YP_974643.1 576211 R 272831 CDS YP_974644.1 121634399 4675143 complement(577638..578747) 1 NC_008767.1 hypothetical protein 578747 4675143 NMC0548 Neisseria meningitidis FAM18 hypothetical protein YP_974644.1 577638 R 272831 CDS YP_974645.1 121634400 4675349 578875..579141 1 NC_008767.1 hypothetical protein 579141 4675349 NMC0549 Neisseria meningitidis FAM18 hypothetical protein YP_974645.1 578875 D 272831 CDS YP_974646.1 121634401 4675300 579350..581206 1 NC_008767.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 581206 secD 4675300 secD Neisseria meningitidis FAM18 preprotein translocase subunit SecD YP_974646.1 579350 D 272831 CDS YP_974647.1 121634402 4675101 581210..582145 1 NC_008767.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 582145 secF 4675101 secF Neisseria meningitidis FAM18 preprotein translocase subunit SecF YP_974647.1 581210 D 272831 CDS YP_974648.1 121634403 4675215 582368..582637 1 NC_008767.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 582637 rpsO 4675215 rpsO Neisseria meningitidis FAM18 30S ribosomal protein S15 YP_974648.1 582368 D 272831 CDS YP_974649.1 121634404 4675223 583019..584143 1 NC_008767.1 polyamine permease ATP-binding protein 584143 4675223 NMC0553 Neisseria meningitidis FAM18 polyamine permease ATP-binding protein YP_974649.1 583019 D 272831 CDS YP_974650.1 121634405 4675352 584159..585124 1 NC_008767.1 polyamine permease inner membrane protein 585124 4675352 NMC0554 Neisseria meningitidis FAM18 polyamine permease inner membrane protein YP_974650.1 584159 D 272831 CDS YP_974651.1 121634406 4675305 585124..586011 1 NC_008767.1 polyamine permease inner membrane protein 586011 4675305 NMC0555 Neisseria meningitidis FAM18 polyamine permease inner membrane protein YP_974651.1 585124 D 272831 CDS YP_974652.1 121634407 4675253 586137..587432 1 NC_008767.1 oxidoreductase 587432 4675253 NMC0556 Neisseria meningitidis FAM18 oxidoreductase YP_974652.1 586137 D 272831 CDS YP_974653.1 121634408 4675307 complement(587677..588981) 1 NC_008767.1 ammonium transporter 588981 amtB 4675307 amtB Neisseria meningitidis FAM18 ammonium transporter YP_974653.1 587677 R 272831 CDS YP_974654.1 121634409 4676375 complement(590199..590594) 1 NC_008767.1 IS1106 transposase 590594 4676375 NMC0558 Neisseria meningitidis FAM18 IS1106 transposase YP_974654.1 590199 R 272831 CDS YP_974655.1 121634410 4675309 complement(591470..592729) 1 NC_008767.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 592729 rho 4675309 rho Neisseria meningitidis FAM18 transcription termination factor Rho YP_974655.1 591470 R 272831 CDS YP_974656.1 121634411 4675601 complement(592949..595333) 1 NC_008767.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 595333 ppsA 4675601 ppsA Neisseria meningitidis FAM18 phosphoenolpyruvate synthase YP_974656.1 592949 R 272831 CDS YP_974657.1 121634412 4676079 595744..596565 1 NC_008767.1 hypothetical protein 596565 4676079 NMC0562 Neisseria meningitidis FAM18 hypothetical protein YP_974657.1 595744 D 272831 CDS YP_974658.1 121634413 4675308 complement(596804..597466) 1 NC_008767.1 phosphatase 597466 4675308 NMC0563 Neisseria meningitidis FAM18 phosphatase YP_974658.1 596804 R 272831 CDS YP_974659.1 121634414 4675310 complement(597479..598333) 1 NC_008767.1 hypothetical protein 598333 4675310 NMC0565 Neisseria meningitidis FAM18 hypothetical protein YP_974659.1 597479 R 272831 CDS YP_974660.1 121634415 4675314 598734..599357 1 NC_008767.1 periplasmic carrier protein 599357 4675314 NMC0566 Neisseria meningitidis FAM18 periplasmic carrier protein YP_974660.1 598734 D 272831 CDS YP_974661.1 121634416 4675312 599609..600769 1 NC_008767.1 polyamine permease substrate-binding protein 600769 4675312 NMC0567 Neisseria meningitidis FAM18 polyamine permease substrate-binding protein YP_974661.1 599609 D 272831 CDS YP_974662.1 121634417 4675319 join(600903..601232,601240..602082) 1 NC_008767.1 glycosyl transferase 602082 4675319 NMC0568 Neisseria meningitidis FAM18 glycosyl transferase YP_974662.1 600903 D 272831 CDS YP_974663.1 121634418 4675322 602123..602653 1 NC_008767.1 hypothetical protein 602653 4675322 NMC0569 Neisseria meningitidis FAM18 hypothetical protein YP_974663.1 602123 D 272831 CDS YP_974664.1 121634419 4675321 complement(602822..604417) 1 NC_008767.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 604417 prfC 4675321 prfC Neisseria meningitidis FAM18 peptide chain release factor 3 YP_974664.1 602822 R 272831 CDS YP_974665.1 121634420 4675969 complement(604524..604919) 1 NC_008767.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 604919 hisI 4675969 hisI Neisseria meningitidis FAM18 phosphoribosyl-AMP cyclohydrolase YP_974665.1 604524 R 272831 CDS YP_974666.1 121634421 4676452 complement(604950..605717) 1 NC_008767.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 605717 hisF 4676452 hisF Neisseria meningitidis FAM18 imidazole glycerol phosphate synthase subunit HisF YP_974666.1 604950 R 272831 CDS YP_974667.1 121634422 4676485 complement(605730..606467) 1 NC_008767.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 606467 hisA 4676485 hisA Neisseria meningitidis FAM18 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_974667.1 605730 R 272831 CDS YP_974668.1 121634423 4676476 complement(606500..607138) 1 NC_008767.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 607138 hisH 4676476 hisH Neisseria meningitidis FAM18 imidazole glycerol phosphate synthase subunit HisH YP_974668.1 606500 R 272831 CDS YP_974669.1 121634424 4676430 complement(607269..608903) 1 NC_008767.1 phosphate acyltransferase 608903 4676430 NMC0575 Neisseria meningitidis FAM18 phosphate acyltransferase YP_974669.1 607269 R 272831 CDS YP_974670.1 121634425 4675330 complement(608956..610014) 1 NC_008767.1 iron-uptake permease ATP-binding protein 610014 fbpC 4675330 fbpC Neisseria meningitidis FAM18 iron-uptake permease ATP-binding protein YP_974670.1 608956 R 272831 CDS YP_974671.1 121634426 4675853 complement(610035..611570) 1 NC_008767.1 iron-uptake permease inner membrane protein 611570 fbpB 4675853 fbpB Neisseria meningitidis FAM18 iron-uptake permease inner membrane protein YP_974671.1 610035 R 272831 CDS YP_974672.1 121634427 4675848 complement(611620..612615) 1 NC_008767.1 major ferric iron binding protein 612615 fbpA 4675848 fbpA Neisseria meningitidis FAM18 major ferric iron binding protein YP_974672.1 611620 R 272831 CDS YP_974673.1 121634428 4675847 complement(612866..613336) 1 NC_008767.1 hypothetical protein 613336 4675847 NMC0579 Neisseria meningitidis FAM18 hypothetical protein YP_974673.1 612866 R 272831 CDS YP_974674.1 121634429 4675327 complement(613394..614770) 1 NC_008767.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 614770 argH 4675327 argH Neisseria meningitidis FAM18 argininosuccinate lyase YP_974674.1 613394 R 272831 CDS YP_974675.1 121634430 4675867 complement(614789..615658) 1 NC_008767.1 UTP-glucose-1-phosphate uridylyltransferase 615658 galU 4675867 galU Neisseria meningitidis FAM18 UTP-glucose-1-phosphate uridylyltransferase YP_974675.1 614789 R 272831 CDS YP_974676.1 121634431 4676629 complement(615686..616285) 1 NC_008767.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 616285 4676629 NMC0582 Neisseria meningitidis FAM18 deoxyribonucleotide triphosphate pyrophosphatase YP_974676.1 615686 R 272831 CDS YP_974677.1 121634432 4675165 complement(616278..616511) 1 NC_008767.1 hypothetical protein 616511 4675165 NMC0583 Neisseria meningitidis FAM18 hypothetical protein YP_974677.1 616278 R 272831 CDS YP_974678.1 121634433 4675332 complement(616619..617200) 1 NC_008767.1 inorganic pyrophosphatase 617200 ppa 4675332 ppa Neisseria meningitidis FAM18 inorganic pyrophosphatase YP_974678.1 616619 R 272831 CDS YP_974679.1 121634434 4676080 complement(617253..617711) 1 NC_008767.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 617711 ntpA 4676080 ntpA Neisseria meningitidis FAM18 dATP pyrophosphohydrolase YP_974679.1 617253 R 272831 CDS YP_974680.1 121634435 4676212 618156..619982 1 NC_008767.1 adhesin 619982 mafB3 4676212 mafB3 Neisseria meningitidis FAM18 adhesin YP_974680.1 618156 D 272831 CDS YP_974681.1 121634436 4675934 619985..620449 1 NC_008767.1 hypothetical protein 620449 4675934 NMC0587 Neisseria meningitidis FAM18 hypothetical protein YP_974681.1 619985 D 272831 CDS YP_974682.1 121634437 4675174 620475..620663 1 NC_008767.1 lipoprotein 620663 4675174 NMC0588 Neisseria meningitidis FAM18 lipoprotein YP_974682.1 620475 D 272831 CDS YP_974683.1 121634438 4675500 620832..621119 1 NC_008767.1 ribonuclease inhibitor barstar 621119 4675500 NMC0589 Neisseria meningitidis FAM18 ribonuclease inhibitor barstar YP_974683.1 620832 D 272831 CDS YP_974684.1 121634439 4675432 622433..622855 1 NC_008767.1 hypothetical protein 622855 4675432 NMC0591 Neisseria meningitidis FAM18 hypothetical protein YP_974684.1 622433 D 272831 CDS YP_974685.1 121634440 4675342 623013..623255 1 NC_008767.1 hypothetical protein 623255 4675342 NMC0592 Neisseria meningitidis FAM18 hypothetical protein YP_974685.1 623013 D 272831 CDS YP_974686.1 121634441 4675436 623333..623578 1 NC_008767.1 hypothetical protein 623578 4675436 NMC0593 Neisseria meningitidis FAM18 hypothetical protein YP_974686.1 623333 D 272831 CDS YP_974687.1 121634442 4675360 623581..623967 1 NC_008767.1 hypothetical protein 623967 4675360 NMC0594 Neisseria meningitidis FAM18 hypothetical protein YP_974687.1 623581 D 272831 CDS YP_974688.1 121634443 4675366 624068..624457 1 NC_008767.1 hypothetical protein 624457 4675366 NMC0595 Neisseria meningitidis FAM18 hypothetical protein YP_974688.1 624068 D 272831 CDS YP_974689.1 121634444 4675456 624579..625520 1 NC_008767.1 adhesin 625520 4675456 NMC0596 Neisseria meningitidis FAM18 adhesin YP_974689.1 624579 D 272831 CDS YP_974690.1 121634445 4675454 625524..626792 1 NC_008767.1 adhesin 626792 4675454 NMC0597 Neisseria meningitidis FAM18 adhesin YP_974690.1 625524 D 272831 CDS YP_974691.1 121634446 4675453 626795..627112 1 NC_008767.1 hypothetical protein 627112 4675453 NMC0598 Neisseria meningitidis FAM18 hypothetical protein YP_974691.1 626795 D 272831 CDS YP_974692.1 121634447 4675459 627246..627923 1 NC_008767.1 hypothetical protein 627923 4675459 NMC0599 Neisseria meningitidis FAM18 hypothetical protein YP_974692.1 627246 D 272831 CDS YP_974693.1 121634448 4675455 627929..628306 1 NC_008767.1 hypothetical protein 628306 4675455 NMC0600 Neisseria meningitidis FAM18 hypothetical protein YP_974693.1 627929 D 272831 CDS YP_974694.1 121634449 4675460 628437..629105 1 NC_008767.1 hypothetical protein 629105 4675460 NMC0601 Neisseria meningitidis FAM18 hypothetical protein YP_974694.1 628437 D 272831 CDS YP_974695.1 121634450 4675475 629109..629381 1 NC_008767.1 hypothetical protein 629381 4675475 NMC0602 Neisseria meningitidis FAM18 hypothetical protein YP_974695.1 629109 D 272831 CDS YP_974696.1 121634451 4675470 629363..629515 1 NC_008767.1 hypothetical protein 629515 4675470 NMC0603 Neisseria meningitidis FAM18 hypothetical protein YP_974696.1 629363 D 272831 CDS YP_974697.1 121634452 4675476 629502..630047 1 NC_008767.1 hypothetical protein 630047 4675476 NMC0604 Neisseria meningitidis FAM18 hypothetical protein YP_974697.1 629502 D 272831 CDS YP_974698.1 121634453 4676473 630041..630664 1 NC_008767.1 hypothetical protein 630664 4676473 NMC0605 Neisseria meningitidis FAM18 hypothetical protein YP_974698.1 630041 D 272831 CDS YP_974699.1 121634454 4675478 630897..631076 1 NC_008767.1 fragment because of a substitution M->H; hypothetical protein 631076 4675478 NMC0606 Neisseria meningitidis FAM18 hypothetical protein YP_974699.1 630897 D 272831 CDS YP_974700.1 121634455 4675479 631107..631508 1 NC_008767.1 hypothetical protein 631508 4675479 NMC0607 Neisseria meningitidis FAM18 hypothetical protein YP_974700.1 631107 D 272831 CDS YP_974701.1 121634456 4676418 631690..632079 1 NC_008767.1 hypothetical protein 632079 4676418 NMC0608 Neisseria meningitidis FAM18 hypothetical protein YP_974701.1 631690 D 272831 CDS YP_974702.1 121634457 4675511 complement(632120..633577) 1 NC_008767.1 transmembrane potassium transporter 633577 4675511 NMC0609 Neisseria meningitidis FAM18 transmembrane potassium transporter YP_974702.1 632120 R 272831 CDS YP_974703.1 121634458 4675527 complement(633592..634482) 1 NC_008767.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 634482 apaH 4675527 apaH Neisseria meningitidis FAM18 diadenosine tetraphosphatase YP_974703.1 633592 R 272831 CDS YP_974704.1 121634459 4676371 complement(634500..634889) 1 NC_008767.1 hypothetical protein 634889 4676371 NMC0611 Neisseria meningitidis FAM18 hypothetical protein YP_974704.1 634500 R 272831 CDS YP_974705.1 121634460 4675980 complement(635025..635549) 1 NC_008767.1 hypothetical protein 635549 nspA 4675980 nspA Neisseria meningitidis FAM18 hypothetical protein YP_974705.1 635025 R 272831 CDS YP_974706.1 121634461 4676221 complement(636136..637335) 1 NC_008767.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 637335 4676221 NMC0613 Neisseria meningitidis FAM18 coproporphyrinogen III oxidase YP_974706.1 636136 R 272831 CDS YP_974707.1 121634462 4675503 complement(637368..639893) 1 NC_008767.1 DNA ligase 639893 ligA 4675503 ligA Neisseria meningitidis FAM18 DNA ligase YP_974707.1 637368 R 272831 CDS YP_974708.1 121634463 4676381 complement(640041..641327) 1 NC_008767.1 hypothetical protein 641327 4676381 NMC0615 Neisseria meningitidis FAM18 hypothetical protein YP_974708.1 640041 R 272831 CDS YP_974709.1 121634464 4675580 complement(641523..642095) 1 NC_008767.1 N-acetyl-anhydromuranmyl-L-alanine amidase 642095 ampD 4675580 ampD Neisseria meningitidis FAM18 N-acetyl-anhydromuranmyl-L-alanine amidase YP_974709.1 641523 R 272831 CDS YP_974710.1 121634465 4676374 642122..643174 1 NC_008767.1 hypothetical protein 643174 4676374 NMC0618 Neisseria meningitidis FAM18 hypothetical protein YP_974710.1 642122 D 272831 CDS YP_974711.1 121634466 4675577 643234..643854 1 NC_008767.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 643854 tmk 4675577 tmk Neisseria meningitidis FAM18 thymidylate kinase YP_974711.1 643234 D 272831 CDS YP_974712.1 121634467 4674866 644076..645356 1 NC_008767.1 malate oxidoreductase 645356 maeA 4674866 maeA Neisseria meningitidis FAM18 malate oxidoreductase YP_974712.1 644076 D 272831 CDS YP_974713.1 121634468 4676332 645903..646937 1 NC_008767.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 646937 lpxK 4676332 lpxK Neisseria meningitidis FAM18 tetraacyldisaccharide 4'-kinase YP_974713.1 645903 D 272831 CDS YP_974714.1 121634469 4676328 647137..647724 1 NC_008767.1 hypothetical protein 647724 4676328 NMC0622 Neisseria meningitidis FAM18 hypothetical protein YP_974714.1 647137 D 272831 CDS YP_974715.1 121634470 4675531 647793..647975 1 NC_008767.1 hypothetical protein 647975 4675531 NMC0623 Neisseria meningitidis FAM18 hypothetical protein YP_974715.1 647793 D 272831 CDS YP_974716.1 121634471 4675581 647972..648733 1 NC_008767.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 648733 kdsB 4675581 kdsB Neisseria meningitidis FAM18 3-deoxy-manno-octulosonate cytidylyltransferase YP_974716.1 647972 D 272831 CDS YP_974717.1 121634472 4676405 648756..649157 1 NC_008767.1 hypothetical protein 649157 4676405 NMC0625 Neisseria meningitidis FAM18 hypothetical protein YP_974717.1 648756 D 272831 CDS YP_974718.1 121634473 4675600 649178..649375 1 NC_008767.1 hypothetical protein 649375 4675600 NMC0626 Neisseria meningitidis FAM18 hypothetical protein YP_974718.1 649178 D 272831 CDS YP_974719.1 121634474 4675595 649353..649469 1 NC_008767.1 hypothetical protein 649469 4675595 NMC0627 Neisseria meningitidis FAM18 hypothetical protein YP_974719.1 649353 D 272831 CDS YP_974720.2 161723301 4675599 650051..650836 1 NC_008767.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 650836 trpA 4675599 trpA Neisseria meningitidis FAM18 tryptophan synthase subunit alpha YP_974720.2 650051 D 272831 CDS YP_974721.2 161723300 4675189 650873..651745 1 NC_008767.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 651745 accD 4675189 accD Neisseria meningitidis FAM18 acetyl-CoA carboxylase subunit beta YP_974721.2 650873 D 272831 CDS YP_974722.1 121634477 4675426 complement(651805..652428) 1 NC_008767.1 hypothetical protein 652428 cnp1 4675426 cnp1 Neisseria meningitidis FAM18 hypothetical protein YP_974722.1 651805 R 272831 CDS YP_974723.1 121634478 4676673 652525..652749 1 NC_008767.1 hypothetical protein 652749 4676673 NMC0631 Neisseria meningitidis FAM18 hypothetical protein YP_974723.1 652525 D 272831 CDS YP_974724.1 121634479 4675590 652750..653355 1 NC_008767.1 lipoprotein 653355 4675590 NMC0632 Neisseria meningitidis FAM18 lipoprotein YP_974724.1 652750 D 272831 CDS YP_974725.1 121634480 4675604 653415..654449 1 NC_008767.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 654449 pyrC 4675604 pyrC Neisseria meningitidis FAM18 dihydroorotase YP_974725.1 653415 D 272831 CDS YP_974726.1 121634481 4675791 complement(654813..655238) 1 NC_008767.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 655238 nusB 4675791 nusB Neisseria meningitidis FAM18 transcription antitermination protein NusB YP_974726.1 654813 R 272831 CDS YP_974727.1 121634482 4676183 complement(655316..655792) 1 NC_008767.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 655792 ribH 4676183 ribH Neisseria meningitidis FAM18 6,7-dimethyl-8-ribityllumazine synthase YP_974727.1 655316 R 272831 CDS YP_974728.1 121634483 4675540 complement(655839..656162) 1 NC_008767.1 hypothetical protein 656162 4675540 NMC0636 Neisseria meningitidis FAM18 hypothetical protein YP_974728.1 655839 R 272831 CDS YP_974729.1 121634484 4675618 656245..657048 1 NC_008767.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 657048 rnc 4675618 rnc Neisseria meningitidis FAM18 ribonuclease III YP_974729.1 656245 D 272831 CDS YP_974730.1 121634485 4675579 657095..658018 1 NC_008767.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 658018 era 4675579 era Neisseria meningitidis FAM18 GTP-binding protein Era YP_974730.1 657095 D 272831 CDS YP_974731.1 121634486 4675888 complement(659053..659679) 1 NC_008767.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 659679 trpF 4675888 trpF Neisseria meningitidis FAM18 N-(5'-phosphoribosyl)anthranilate isomerase YP_974731.1 659053 R 272831 CDS YP_974732.1 121634487 4674828 complement(659738..660229) 1 NC_008767.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 660229 greB 4674828 greB Neisseria meningitidis FAM18 transcription elongation factor GreB YP_974732.1 659738 R 272831 CDS YP_974733.1 121634488 4676480 complement(660329..661873) 1 NC_008767.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 661873 purF 4676480 purF Neisseria meningitidis FAM18 amidophosphoribosyltransferase YP_974733.1 660329 R 272831 CDS YP_974734.1 121634489 4675368 complement(662185..662682) 1 NC_008767.1 hypothetical protein 662682 4675368 NMC0642 Neisseria meningitidis FAM18 hypothetical protein YP_974734.1 662185 R 272831 CDS YP_974735.1 121634490 4675607 complement(662675..663673) 1 NC_008767.1 tetrapac protein 663673 tpc 4675607 tpc Neisseria meningitidis FAM18 tetrapac protein YP_974735.1 662675 R 272831 CDS YP_974736.1 121634491 4674845 complement(663686..664960) 1 NC_008767.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase 664960 folC 4674845 folC Neisseria meningitidis FAM18 bifunctional folylpolyglutamate synthase/dihydrofolate synthase YP_974736.1 663686 R 272831 CDS YP_974737.1 121634492 4676705 complement(664992..665432) 1 NC_008767.1 transcriptional regulator 665432 folI 4676705 folI Neisseria meningitidis FAM18 transcriptional regulator YP_974737.1 664992 R 272831 CDS YP_974738.1 121634493 4676700 complement(665437..665811) 1 NC_008767.1 hypothetical protein 665811 4676700 NMC0646 Neisseria meningitidis FAM18 hypothetical protein YP_974738.1 665437 R 272831 CDS YP_974739.1 121634494 4675608 complement(665869..666618) 1 NC_008767.1 amino acid permease 666618 4675608 NMC0647 Neisseria meningitidis FAM18 amino acid permease YP_974739.1 665869 R 272831 CDS YP_974740.1 121634495 4675565 complement(666770..667549) 1 NC_008767.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 667549 ksgA 4675565 ksgA Neisseria meningitidis FAM18 dimethyladenosine transferase YP_974740.1 666770 R 272831 CDS YP_974741.1 121634496 4676420 667740..668456 1 NC_008767.1 hypothetical protein 668456 4676420 NMC0649 Neisseria meningitidis FAM18 hypothetical protein YP_974741.1 667740 D 272831 CDS YP_974742.1 121634497 4675658 668641..669843 1 NC_008767.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 669843 trpB 4675658 trpB Neisseria meningitidis FAM18 tryptophan synthase subunit beta YP_974742.1 668641 D 272831 CDS YP_974743.1 121634498 4675190 complement(670022..674728) 1 NC_008767.1 IgA1 protease 674728 iga 4675190 iga Neisseria meningitidis FAM18 IgA1 protease YP_974743.1 670022 R 272831 CDS YP_974744.1 121634499 4676411 676012..678087 1 NC_008767.1 competence protein 678087 comA 4676411 comA Neisseria meningitidis FAM18 competence protein YP_974744.1 676012 D 272831 CDS YP_974745.1 121634500 4676585 complement(678145..678948) 1 NC_008767.1 competence lipoprotein 678948 comL 4676585 comL Neisseria meningitidis FAM18 competence lipoprotein YP_974745.1 678145 R 272831 CDS YP_974746.1 121634501 4676586 678947..680071 1 NC_008767.1 ribosomal large subunit pseudouridine synthase D 680071 rluD 4676586 rluD Neisseria meningitidis FAM18 ribosomal large subunit pseudouridine synthase D YP_974746.1 678947 D 272831 CDS YP_974747.1 121634502 4675594 complement(680223..681215) 1 NC_008767.1 transmembrane transport protein 681215 4675594 NMC0655 Neisseria meningitidis FAM18 transmembrane transport protein YP_974747.1 680223 R 272831 CDS YP_974748.1 121634503 4675626 681777..682556 1 NC_008767.1 hypothetical protein 682556 4675626 NMC0656 Neisseria meningitidis FAM18 hypothetical protein YP_974748.1 681777 D 272831 CDS YP_974749.1 121634504 4676683 682608..683087 1 NC_008767.1 lipoprotein 683087 4676683 NMC0657 Neisseria meningitidis FAM18 lipoprotein YP_974749.1 682608 D 272831 CDS YP_974750.1 121634505 4676532 683089..684087 1 NC_008767.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 684087 holA 4676532 holA Neisseria meningitidis FAM18 DNA polymerase III subunit delta YP_974750.1 683089 D 272831 CDS YP_974751.1 121634506 4676435 684208..684627 1 NC_008767.1 hypothetical protein 684627 4676435 NMC0659 Neisseria meningitidis FAM18 hypothetical protein YP_974751.1 684208 D 272831 CDS YP_974752.1 121634507 4676523 684652..685218 1 NC_008767.1 hypothetical protein 685218 4676523 NMC0660 Neisseria meningitidis FAM18 hypothetical protein YP_974752.1 684652 D 272831 CDS YP_974753.1 121634508 4675814 complement(685302..686186) 1 NC_008767.1 hypothetical protein 686186 4675814 NMC0661 Neisseria meningitidis FAM18 hypothetical protein YP_974753.1 685302 R 272831 CDS YP_974754.1 121634509 4675823 complement(686670..687542) 1 NC_008767.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 687542 rpoH 4675823 rpoH Neisseria meningitidis FAM18 RNA polymerase factor sigma-32 YP_974754.1 686670 R 272831 CDS YP_974755.1 121634510 4675316 complement(687797..689341) 1 NC_008767.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 689341 lnt 4675316 lnt Neisseria meningitidis FAM18 apolipoprotein N-acyltransferase YP_974755.1 687797 R 272831 CDS YP_974756.1 121634511 4676383 complement(689375..690130) 1 NC_008767.1 hypothetical protein 690130 4676383 NMC0665 Neisseria meningitidis FAM18 hypothetical protein YP_974756.1 689375 R 272831 CDS YP_974757.1 121634512 4676663 690326..690646 1 NC_008767.1 hypothetical protein 690646 4676663 NMC0666 Neisseria meningitidis FAM18 hypothetical protein YP_974757.1 690326 D 272831 CDS YP_974758.1 121634513 4675724 690799..691089 1 NC_008767.1 hypothetical protein 691089 4675724 NMC0667 Neisseria meningitidis FAM18 hypothetical protein YP_974758.1 690799 D 272831 CDS YP_974759.1 121634514 4675836 complement(691152..691553) 1 NC_008767.1 cytochrome C 691553 4675836 NMC0668 Neisseria meningitidis FAM18 cytochrome C YP_974759.1 691152 R 272831 CDS YP_974760.1 121634515 4675731 complement(691745..692755) 1 NC_008767.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 692755 hemH 4675731 hemH Neisseria meningitidis FAM18 ferrochelatase YP_974760.1 691745 R 272831 CDS YP_974761.1 121634516 4676500 complement(692837..693952) 1 NC_008767.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 693952 tgt 4676500 tgt Neisseria meningitidis FAM18 queuine tRNA-ribosyltransferase YP_974761.1 692837 R 272831 CDS YP_974762.1 121634517 4675203 694227..696173 1 NC_008767.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 696173 thrS 4675203 thrS Neisseria meningitidis FAM18 threonyl-tRNA synthetase YP_974762.1 694227 D 272831 CDS YP_974763.1 121634518 4675195 696191..696712 1 NC_008767.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 696712 infC 4675195 infC Neisseria meningitidis FAM18 translation initiation factor IF-3 YP_974763.1 696191 D 272831 CDS YP_974764.1 121634519 4676433 696859..697056 1 NC_008767.1 50S ribosomal protein L35 697056 rpmI 4676433 rpmI Neisseria meningitidis FAM18 50S ribosomal protein L35 YP_974764.1 696859 D 272831 CDS YP_974765.1 121634520 4675730 697069..697428 1 NC_008767.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 697428 rplT 4675730 rplT Neisseria meningitidis FAM18 50S ribosomal protein L20 YP_974765.1 697069 D 272831 CDS YP_974766.2 161723299 4675372 697774..698766 1 NC_008767.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 698766 pheS 4675372 pheS Neisseria meningitidis FAM18 phenylalanyl-tRNA synthetase subunit alpha YP_974766.2 697774 D 272831 CDS YP_974767.1 121634522 4676112 699090..699536 1 NC_008767.1 NmeDIP very-short-patch-repair endonuclease 699536 vsr 4676112 vsr Neisseria meningitidis FAM18 NmeDIP very-short-patch-repair endonuclease YP_974767.1 699090 D 272831 CDS YP_974768.1 121634523 4676707 699550..700701 1 NC_008767.1 modification methylase NmeDI 700701 nmeDIMP 4676707 nmeDIMP Neisseria meningitidis FAM18 modification methylase NmeDI YP_974768.1 699550 D 272831 CDS YP_974769.1 121634524 4676227 700673..701728 1 NC_008767.1 type II restriction enzyme NmeDIP 701728 4676227 NMC0680 Neisseria meningitidis FAM18 type II restriction enzyme NmeDIP YP_974769.1 700673 D 272831 CDS YP_974770.1 121634525 4675727 701783..704146 1 NC_008767.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 704146 pheT 4675727 pheT Neisseria meningitidis FAM18 phenylalanyl-tRNA synthetase subunit beta YP_974770.1 701783 D 272831 CDS YP_974771.1 121634526 4676122 704220..704522 1 NC_008767.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 704522 ihfA 4676122 ihfA Neisseria meningitidis FAM18 integration host factor subunit alpha YP_974771.1 704220 D 272831 CDS YP_974772.1 121634527 4676467 704524..704814 1 NC_008767.1 hypothetical protein 704814 4676467 NMC0683 Neisseria meningitidis FAM18 hypothetical protein YP_974772.1 704524 D 272831 CDS YP_974773.1 121634528 4675743 705144..705629 1 NC_008767.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 705629 fxsA 4675743 fxsA Neisseria meningitidis FAM18 FxsA protein YP_974773.1 705144 D 272831 CDS YP_974774.1 121634529 4675756 706341..707642 1 NC_008767.1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 707642 bioA 4675756 bioA Neisseria meningitidis FAM18 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_974774.1 706341 D 272831 CDS YP_974775.1 121634530 4676626 707639..708286 1 NC_008767.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 708286 bioD 4676626 bioD Neisseria meningitidis FAM18 dithiobiotin synthetase YP_974775.1 707639 D 272831 CDS YP_974776.1 121634531 4676554 708253..708777 1 NC_008767.1 hypothetical protein 708777 4676554 NMC0687 Neisseria meningitidis FAM18 hypothetical protein YP_974776.1 708253 D 272831 CDS YP_974777.1 121634532 4675755 708807..709697 1 NC_008767.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 709697 ubiA 4675755 ubiA Neisseria meningitidis FAM18 4-hydroxybenzoate octaprenyltransferase YP_974777.1 708807 D 272831 CDS YP_974778.1 121634533 4676208 709882..710331 1 NC_008767.1 regulatory protein 710331 4676208 NMC0689 Neisseria meningitidis FAM18 regulatory protein YP_974778.1 709882 D 272831 CDS YP_974779.1 121634534 4675781 710335..711297 1 NC_008767.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 711297 4675781 NMC0690 Neisseria meningitidis FAM18 HPr kinase/phosphorylase YP_974779.1 710335 D 272831 CDS YP_974780.1 121634535 4675784 711278..712132 1 NC_008767.1 hypothetical protein 712132 4675784 NMC0691 Neisseria meningitidis FAM18 hypothetical protein YP_974780.1 711278 D 272831 CDS YP_974781.1 121634536 4675776 712213..713154 1 NC_008767.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 713154 rbgA 4675776 rbgA Neisseria meningitidis FAM18 ribosomal biogenesis GTPase YP_974781.1 712213 D 272831 CDS YP_974782.1 121634537 4675789 713255..713857 1 NC_008767.1 hypothetical protein 713857 4675789 NMC0693 Neisseria meningitidis FAM18 hypothetical protein YP_974782.1 713255 D 272831 CDS YP_974783.1 121634538 4675804 714041..715714 1 NC_008767.1 DNA repair protein 715714 recN 4675804 recN Neisseria meningitidis FAM18 DNA repair protein YP_974783.1 714041 D 272831 CDS YP_974784.1 121634539 4675749 complement(716796..718415) 1 NC_008767.1 hypothetical protein 718415 4675749 NMC0695 Neisseria meningitidis FAM18 hypothetical protein YP_974784.1 716796 R 272831 CDS YP_974785.1 121634540 4675797 718535..718903 1 NC_008767.1 hypothetical protein 718903 4675797 NMC0696 Neisseria meningitidis FAM18 hypothetical protein YP_974785.1 718535 D 272831 CDS YP_974786.1 121634541 4675948 718946..719683 1 NC_008767.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 719683 ubiE 4675948 ubiE Neisseria meningitidis FAM18 ubiquinone/menaquinone biosynthesis methyltransferase YP_974786.1 718946 D 272831 CDS YP_974787.1 121634542 4676209 719903..720382 1 NC_008767.1 hypothetical protein 720382 4676209 NMC0698 Neisseria meningitidis FAM18 hypothetical protein YP_974787.1 719903 D 272831 CDS YP_974788.1 121634543 4675945 complement(720507..721001) 1 NC_008767.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine- pyrophosphokinase 721001 folK 4675945 folK Neisseria meningitidis FAM18 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine- pyrophosphokinase YP_974788.1 720507 R 272831 CDS YP_974789.1 121634544 4676686 complement(721011..721385) 1 NC_008767.1 regulator 721385 4676686 NMC0700 Neisseria meningitidis FAM18 regulator YP_974789.1 721011 R 272831 CDS YP_974790.1 121634545 4675830 complement(721439..722005) 1 NC_008767.1 hypothetical protein 722005 4675830 NMC0701 Neisseria meningitidis FAM18 hypothetical protein YP_974790.1 721439 R 272831 CDS YP_974791.1 121634546 4675902 complement(722089..722382) 1 NC_008767.1 regulator 722382 hfq 4675902 hfq Neisseria meningitidis FAM18 regulator YP_974791.1 722089 R 272831 CDS YP_974792.1 121634547 4675852 complement(722511..723461) 1 NC_008767.1 D-alanyl-D-alanine-endopeptidase 723461 4675852 NMC0703 Neisseria meningitidis FAM18 D-alanyl-D-alanine-endopeptidase YP_974792.1 722511 R 272831 CDS YP_974793.1 121634548 4675146 723707..724210 1 NC_008767.1 hypothetical protein 724210 4675146 NMC0704 Neisseria meningitidis FAM18 hypothetical protein YP_974793.1 723707 D 272831 CDS YP_974794.1 121634549 4675920 724262..725137 1 NC_008767.1 integrase/recombinase 725137 xerD 4675920 xerD Neisseria meningitidis FAM18 integrase/recombinase YP_974794.1 724262 D 272831 CDS YP_974795.1 121634550 4676681 725309..725509 1 NC_008767.1 ferredoxin 725509 4676681 NMC0706 Neisseria meningitidis FAM18 ferredoxin YP_974795.1 725309 D 272831 CDS YP_974796.1 121634551 4675913 725675..725908 1 NC_008767.1 thioredoxin 725908 4675913 NMC0707 Neisseria meningitidis FAM18 thioredoxin YP_974796.1 725675 D 272831 CDS YP_974797.1 121634552 4675884 complement(726383..727246) 1 NC_008767.1 dTDP-4-dehydrorhamnose reductase 727246 rfbD 4675884 rfbD Neisseria meningitidis FAM18 dTDP-4-dehydrorhamnose reductase YP_974797.1 726383 R 272831 CDS YP_974798.1 121634553 4675542 727259..728308 1 NC_008767.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 728308 purC 4675542 purC Neisseria meningitidis FAM18 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_974798.1 727259 D 272831 CDS YP_974799.1 121634554 4676023 728530..730665 1 NC_008767.1 polynucleotide phosphorylase 730665 pnp 4676023 pnp Neisseria meningitidis FAM18 polynucleotide phosphorylase YP_974799.1 728530 D 272831 CDS YP_974800.1 121634555 4675954 complement(730737..731405) 1 NC_008767.1 hypothetical protein 731405 4675954 NMC0711 Neisseria meningitidis FAM18 hypothetical protein YP_974800.1 730737 R 272831 CDS YP_974801.1 121634556 4675880 complement(731419..731739) 1 NC_008767.1 lipoprotein 731739 4675880 NMC0712 Neisseria meningitidis FAM18 lipoprotein YP_974801.1 731419 R 272831 CDS YP_974802.1 121634557 4675154 731852..732703 1 NC_008767.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 732703 dapF 4675154 dapF Neisseria meningitidis FAM18 diaminopimelate epimerase YP_974802.1 731852 D 272831 CDS YP_974803.1 121634558 4676001 732700..733305 1 NC_008767.1 hypothetical protein 733305 4676001 NMC0714 Neisseria meningitidis FAM18 hypothetical protein YP_974803.1 732700 D 272831 CDS YP_974804.1 121634559 4675856 733445..734431 1 NC_008767.1 cysteine synthase 734431 cysK 4675856 cysK Neisseria meningitidis FAM18 cysteine synthase YP_974804.1 733445 D 272831 CDS YP_974805.1 121634560 4676021 734868..735848 1 NC_008767.1 hypothetical protein 735848 4676021 NMC0717 Neisseria meningitidis FAM18 hypothetical protein YP_974805.1 734868 D 272831 CDS YP_974806.1 121634561 4675870 complement(736262..737281) 1 NC_008767.1 signal peptidase I 737281 lepB 4675870 lepB Neisseria meningitidis FAM18 signal peptidase I YP_974806.1 736262 R 272831 CDS YP_974807.1 121634562 4676398 complement(737424..739217) 1 NC_008767.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 739217 lepA 4676398 lepA Neisseria meningitidis FAM18 GTP-binding protein LepA YP_974807.1 737424 R 272831 CDS YP_974808.1 121634563 4676408 complement(739360..740115) 1 NC_008767.1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 740115 pfs 4676408 pfs Neisseria meningitidis FAM18 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_974808.1 739360 R 272831 CDS YP_974809.1 121634564 4676150 740247..741359 1 NC_008767.1 pilus retraction protein 741359 pilT2 4676150 pilT2 Neisseria meningitidis FAM18 pilus retraction protein YP_974809.1 740247 D 272831 CDS YP_974810.1 121634565 4676032 741394..742371 1 NC_008767.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 742371 holB 4676032 holB Neisseria meningitidis FAM18 DNA polymerase III subunit delta' YP_974810.1 741394 D 272831 CDS YP_974811.1 121634566 4676436 742375..742725 1 NC_008767.1 pilus biogenesis protein 742725 4676436 NMC0723 Neisseria meningitidis FAM18 pilus biogenesis protein YP_974811.1 742375 D 272831 CDS YP_974812.1 121634567 4675153 742730..743509 1 NC_008767.1 hypothetical protein 743509 4675153 NMC0724 Neisseria meningitidis FAM18 hypothetical protein YP_974812.1 742730 D 272831 CDS YP_974813.1 121634568 4676708 743851..744162 1 NC_008767.1 hypothetical protein 744162 4676708 NMC0726 Neisseria meningitidis FAM18 hypothetical protein YP_974813.1 743851 D 272831 CDS YP_974814.1 121634569 4674744 744268..744894 1 NC_008767.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 744894 upp 4674744 upp Neisseria meningitidis FAM18 uracil phosphoribosyltransferase YP_974814.1 744268 D 272831 CDS YP_974815.1 121634570 4676475 744917..745237 1 NC_008767.1 hypothetical protein 745237 4676475 NMC0728 Neisseria meningitidis FAM18 hypothetical protein YP_974815.1 744917 D 272831 CDS YP_974816.1 121634571 4676518 745640..746062 1 NC_008767.1 secreted protein 746062 4676518 NMC0729 Neisseria meningitidis FAM18 secreted protein YP_974816.1 745640 D 272831 CDS YP_974817.1 121634572 4676505 746089..746841 1 NC_008767.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 746841 hemD 4676505 hemD Neisseria meningitidis FAM18 uroporphyrinogen-III synthase YP_974817.1 746089 D 272831 CDS YP_974818.1 121634573 4676674 746856..748190 1 NC_008767.1 hypothetical protein 748190 4676674 NMC0731 Neisseria meningitidis FAM18 hypothetical protein YP_974818.1 746856 D 272831 CDS YP_974819.1 121634574 4676697 748187..749404 1 NC_008767.1 hypothetical protein 749404 4676697 NMC0732 Neisseria meningitidis FAM18 hypothetical protein YP_974819.1 748187 D 272831 CDS YP_974820.1 121634575 4676623 749479..750543 1 NC_008767.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 750543 hemE 4676623 hemE Neisseria meningitidis FAM18 uroporphyrinogen decarboxylase YP_974820.1 749479 D 272831 CDS YP_974821.1 121634576 4676499 750706..752100 1 NC_008767.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 752100 radA 4676499 radA Neisseria meningitidis FAM18 DNA repair protein RadA YP_974821.1 750706 D 272831 CDS YP_974822.1 121634577 4675772 complement(752375..752854) 1 NC_008767.1 hypothetical protein 752854 4675772 NMC0735 Neisseria meningitidis FAM18 hypothetical protein YP_974822.1 752375 R 272831 CDS YP_974823.1 121634578 4676511 complement(752986..753429) 1 NC_008767.1 hypothetical protein 753429 4676511 NMC0736 Neisseria meningitidis FAM18 hypothetical protein YP_974823.1 752986 R 272831 CDS YP_974824.1 121634579 4675668 complement(753384..756998) 1 NC_008767.1 exodeoxyribonuclease V subunit beta 756998 recB 4675668 recB Neisseria meningitidis FAM18 exodeoxyribonuclease V subunit beta YP_974824.1 753384 R 272831 CDS YP_974825.1 121634580 4675753 complement(757231..758349) 1 NC_008767.1 hypothetical protein 758349 4675753 NMC0738 Neisseria meningitidis FAM18 hypothetical protein YP_974825.1 757231 R 272831 CDS YP_974826.1 121634581 4676415 758424..759251 1 NC_008767.1 amino acid permease 759251 4676415 NMC0739 Neisseria meningitidis FAM18 amino acid permease YP_974826.1 758424 D 272831 CDS YP_974827.1 121634582 4676445 759241..759957 1 NC_008767.1 amino acid permease 759957 4676445 NMC0741 Neisseria meningitidis FAM18 amino acid permease YP_974827.1 759241 D 272831 CDS YP_974828.1 121634583 4676386 759967..760722 1 NC_008767.1 amino acid permease 760722 4676386 NMC0742 Neisseria meningitidis FAM18 amino acid permease YP_974828.1 759967 D 272831 CDS YP_974829.1 121634584 4676409 complement(760742..762124) 1 NC_008767.1 phosphoglucomutase 762124 pgm 4676409 pgm Neisseria meningitidis FAM18 phosphoglucomutase YP_974829.1 760742 R 272831 CDS YP_974830.1 121634585 4676131 complement(762287..762796) 1 NC_008767.1 peptidyl-prolyl cis-trans isomerase B 762796 ppiB 4676131 ppiB Neisseria meningitidis FAM18 peptidyl-prolyl cis-trans isomerase B YP_974830.1 762287 R 272831 CDS YP_974831.1 121634586 4676075 complement(762915..764330) 1 NC_008767.1 transmembrane transport protein 764330 4676075 NMC0745 Neisseria meningitidis FAM18 transmembrane transport protein YP_974831.1 762915 R 272831 CDS YP_974832.1 121634587 4676361 complement(764561..764884) 1 NC_008767.1 hypothetical protein 764884 4676361 NMC0746 Neisseria meningitidis FAM18 hypothetical protein YP_974832.1 764561 R 272831 CDS YP_974833.1 121634588 4674745 complement(765187..765765) 1 NC_008767.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 765765 pth 4674745 pth Neisseria meningitidis FAM18 peptidyl-tRNA hydrolase YP_974833.1 765187 R 272831 CDS YP_974834.1 121634589 4675985 complement(765818..766096) 1 NC_008767.1 hypothetical protein 766096 4675985 NMC0748 Neisseria meningitidis FAM18 hypothetical protein YP_974834.1 765818 R 272831 CDS YP_974835.1 121634590 4676333 complement(766089..766532) 1 NC_008767.1 hypothetical protein 766532 4676333 NMC0749 Neisseria meningitidis FAM18 hypothetical protein YP_974835.1 766089 R 272831 CDS YP_974836.1 121634591 4676271 complement(766741..768708) 1 NC_008767.1 ATP-dependent zinc metallopeptidase 768708 ftsH 4676271 ftsH Neisseria meningitidis FAM18 ATP-dependent zinc metallopeptidase YP_974836.1 766741 R 272831 CDS YP_974837.1 121634592 4676658 complement(768772..769392) 1 NC_008767.1 cell division protein 769392 ftsJ 4676658 ftsJ Neisseria meningitidis FAM18 cell division protein YP_974837.1 768772 R 272831 CDS YP_974838.1 121634593 4676649 769466..769786 1 NC_008767.1 hypothetical protein 769786 4676649 NMC0752 Neisseria meningitidis FAM18 hypothetical protein YP_974838.1 769466 D 272831 CDS YP_974839.1 121634594 4676278 769954..770970 1 NC_008767.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 770970 hemB 4676278 hemB Neisseria meningitidis FAM18 delta-aminolevulinic acid dehydratase YP_974839.1 769954 D 272831 CDS YP_974840.1 121634595 4676350 complement(771033..772259) 1 NC_008767.1 carbon-sulfur lyase 772259 4676350 NMC0754 Neisseria meningitidis FAM18 carbon-sulfur lyase YP_974840.1 771033 R 272831 CDS YP_974841.2 229270475 4676233 772382..773155 1 NC_008767.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase 773155 4676233 NMC0755 Neisseria meningitidis FAM18 GTP cyclohydrolase YP_974841.2 772382 D 272831 CDS YP_974842.1 121634597 4676210 773355..774020 1 NC_008767.1 NAD(P)H-flavin oxidoreductase 774020 4676210 NMC0756 Neisseria meningitidis FAM18 NAD(P)H-flavin oxidoreductase YP_974842.1 773355 D 272831 CDS YP_974843.1 121634598 4676228 complement(774075..774833) 1 NC_008767.1 RNA-binding protein 774833 4676228 NMC0757 Neisseria meningitidis FAM18 RNA-binding protein YP_974843.1 774075 R 272831 CDS YP_974844.1 121634599 4676009 complement(774858..775748) 1 NC_008767.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 775748 ppnK 4676009 ppnK Neisseria meningitidis FAM18 inorganic polyphosphate/ATP-NAD kinase YP_974844.1 774858 R 272831 CDS YP_974845.1 121634600 4676189 complement(775768..776334) 1 NC_008767.1 hypothetical protein 776334 4676189 NMC0759 Neisseria meningitidis FAM18 hypothetical protein YP_974845.1 775768 R 272831 CDS YP_974846.1 121634601 4676136 complement(776385..777161) 1 NC_008767.1 hypothetical protein 777161 4676136 NMC0760 Neisseria meningitidis FAM18 hypothetical protein YP_974846.1 776385 R 272831 CDS YP_974847.1 121634602 4676145 complement(777216..777866) 1 NC_008767.1 TetR family transcriptional regulator 777866 4676145 NMC0761 Neisseria meningitidis FAM18 TetR family transcriptional regulator YP_974847.1 777216 R 272831 CDS YP_974848.1 121634603 4676008 complement(777878..778918) 1 NC_008767.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 778918 murB 4676008 murB Neisseria meningitidis FAM18 UDP-N-acetylenolpyruvoylglucosamine reductase YP_974848.1 777878 R 272831 CDS YP_974849.1 121634604 4676268 complement(779097..780476) 1 NC_008767.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 780476 4676268 NMC0763 Neisseria meningitidis FAM18 multidrug efflux protein YP_974849.1 779097 R 272831 CDS YP_974850.1 121634605 4676036 780811..781962 1 NC_008767.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase 781962 hisZ 4676036 hisZ Neisseria meningitidis FAM18 ATP phosphoribosyltransferase YP_974850.1 780811 D 272831 CDS YP_974851.1 121634606 4676096 782060..783364 1 NC_008767.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 783364 purA 4676096 purA Neisseria meningitidis FAM18 adenylosuccinate synthetase YP_974851.1 782060 D 272831 CDS YP_974852.1 121634607 4675798 complement(783751..784590) 1 NC_008767.1 metalloprotease; heat shock protein HtpX 784590 htpX 4675798 htpX Neisseria meningitidis FAM18 heat shock protein HtpX YP_974852.1 783751 R 272831 CDS YP_974853.1 121634608 4676454 784805..785452 1 NC_008767.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 785452 adk 4676454 adk Neisseria meningitidis FAM18 adenylate kinase YP_974853.1 784805 D 272831 CDS YP_974854.1 121634609 4675505 785978..786718 1 NC_008767.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 786718 pyrF 4675505 pyrF Neisseria meningitidis FAM18 orotidine 5'-phosphate decarboxylase YP_974854.1 785978 D 272831 CDS YP_974855.1 121634610 4675777 786773..787744 1 NC_008767.1 DP-heptose synthetase 787744 rfaE 4675777 rfaE Neisseria meningitidis FAM18 DP-heptose synthetase YP_974855.1 786773 D 272831 CDS YP_974856.1 121634611 4675732 787781..789016 1 NC_008767.1 deleted EC_number 2.1.1.73; modification methylase 789016 nmgII 4675732 nmgII Neisseria meningitidis FAM18 modification methylase YP_974856.1 787781 D 272831 CDS YP_974857.1 121634612 4675952 789018..790136 1 NC_008767.1 type II restriction endonuclease 790136 nmgI 4675952 nmgI Neisseria meningitidis FAM18 type II restriction endonuclease YP_974857.1 789018 D 272831 CDS YP_974858.1 121634613 4675951 790177..791181 1 NC_008767.1 ADP-L-glycero-D-manno-heptose-6-epimerase 791181 rfaD 4675951 rfaD Neisseria meningitidis FAM18 ADP-L-glycero-D-manno-heptose-6-epimerase YP_974858.1 790177 D 272831 CDS YP_974859.1 121634614 4675726 complement(791245..793560) 1 NC_008767.1 ATP-dependent protease ATP-binding protein 793560 clpA 4675726 clpA Neisseria meningitidis FAM18 ATP-dependent protease ATP-binding protein YP_974859.1 791245 R 272831 CDS YP_974860.1 121634615 4676694 complement(793544..793846) 1 NC_008767.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 793846 clpS 4676694 clpS Neisseria meningitidis FAM18 ATP-dependent Clp protease adaptor protein ClpS YP_974860.1 793544 R 272831 CDS YP_974861.1 121634616 4676115 794089..794292 1 NC_008767.1 transcriptional regulator 794292 cspA 4676115 cspA Neisseria meningitidis FAM18 transcriptional regulator YP_974861.1 794089 D 272831 CDS YP_974862.1 121634617 4676615 complement(794589..795920) 1 NC_008767.1 hypothetical protein 795920 4676615 NMC0777 Neisseria meningitidis FAM18 hypothetical protein YP_974862.1 794589 R 272831 CDS YP_974863.1 121634618 4675712 796063..796581 1 NC_008767.1 hypothetical protein 796581 4675712 NMC0778 Neisseria meningitidis FAM18 hypothetical protein YP_974863.1 796063 D 272831 CDS YP_974864.1 121634619 4675717 796616..797362 1 NC_008767.1 hypothetical protein 797362 4675717 NMC0779 Neisseria meningitidis FAM18 hypothetical protein YP_974864.1 796616 D 272831 CDS YP_974865.1 121634620 4675700 797414..799114 1 NC_008767.1 single-stranded-DNA-specific exonuclease 799114 recJ 4675700 recJ Neisseria meningitidis FAM18 single-stranded-DNA-specific exonuclease YP_974865.1 797414 D 272831 CDS YP_974866.1 121634621 4675748 799483..800829 1 NC_008767.1 poly(A) polymerase 800829 pcnB 4675748 pcnB Neisseria meningitidis FAM18 poly(A) polymerase YP_974866.1 799483 D 272831 CDS YP_974867.1 121634622 4676134 800974..801300 1 NC_008767.1 hypothetical protein 801300 4676134 NMC0782 Neisseria meningitidis FAM18 hypothetical protein YP_974867.1 800974 D 272831 CDS YP_974868.1 121634623 4675683 complement(801404..802357) 1 NC_008767.1 hypothetical protein 802357 4675683 NMC0784 Neisseria meningitidis FAM18 hypothetical protein YP_974868.1 801404 R 272831 CDS YP_974869.1 121634624 4675689 803887..804591 1 NC_008767.1 hypothetical protein 804591 4675689 NMC0788 Neisseria meningitidis FAM18 hypothetical protein YP_974869.1 803887 D 272831 CDS YP_974870.1 121634625 4675694 complement(804655..805221) 1 NC_008767.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 805221 dcd 4675694 dcd Neisseria meningitidis FAM18 deoxycytidine triphosphate deaminase YP_974870.1 804655 R 272831 CDS YP_974871.1 121634626 4675682 complement(805287..805703) 1 NC_008767.1 hypothetical protein 805703 4675682 NMC0790 Neisseria meningitidis FAM18 hypothetical protein YP_974871.1 805287 R 272831 CDS YP_974872.1 121634627 4675684 complement(805765..806664) 1 NC_008767.1 Required for efficient pilin antigenic variation; recombination associated protein 806664 rdgC 4675684 rdgC Neisseria meningitidis FAM18 recombination associated protein YP_974872.1 805765 R 272831 CDS YP_974873.1 121634628 4675763 complement(806695..808152) 1 NC_008767.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 808152 engA 4675763 engA Neisseria meningitidis FAM18 GTP-binding protein EngA YP_974873.1 806695 R 272831 CDS YP_974874.1 121634629 4675676 complement(808302..808931) 1 NC_008767.1 hypothetical protein 808931 4675676 NMC0793 Neisseria meningitidis FAM18 hypothetical protein YP_974874.1 808302 R 272831 CDS YP_974875.1 121634630 4675679 complement(808932..810227) 1 NC_008767.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 810227 hisS 4675679 hisS Neisseria meningitidis FAM18 histidyl-tRNA synthetase YP_974875.1 808932 R 272831 CDS YP_974876.1 121634631 4676342 complement(810354..811019) 1 NC_008767.1 hypothetical protein 811019 4676342 NMC0795 Neisseria meningitidis FAM18 hypothetical protein YP_974876.1 810354 R 272831 CDS YP_974877.1 121634632 4675681 complement(811292..811828) 1 NC_008767.1 hypothetical protein 811828 4675681 NMC0796 Neisseria meningitidis FAM18 hypothetical protein YP_974877.1 811292 R 272831 CDS YP_974878.1 121634633 4675659 complement(811996..812196) 1 NC_008767.1 hypothetical protein 812196 4675659 NMC0798 Neisseria meningitidis FAM18 hypothetical protein YP_974878.1 811996 R 272831 CDS YP_974879.1 121634634 4675662 complement(812788..813153) 1 NC_008767.1 hypothetical protein 813153 4675662 NMC0800 Neisseria meningitidis FAM18 hypothetical protein YP_974879.1 812788 R 272831 CDS YP_974880.1 121634635 4675552 complement(813135..813680) 1 NC_008767.1 hypothetical protein 813680 4675552 NMC0801 Neisseria meningitidis FAM18 hypothetical protein YP_974880.1 813135 R 272831 CDS YP_974881.1 121634636 4675553 complement(813843..814139) 1 NC_008767.1 hypothetical protein 814139 4675553 NMC0802 Neisseria meningitidis FAM18 hypothetical protein YP_974881.1 813843 R 272831 CDS YP_974882.1 121634637 4675557 complement(814381..814671) 1 NC_008767.1 hypothetical protein 814671 4675557 NMC0803 Neisseria meningitidis FAM18 hypothetical protein YP_974882.1 814381 R 272831 CDS YP_974883.1 121634638 4675536 complement(814991..815239) 1 NC_008767.1 hypothetical protein 815239 4675536 NMC0804 Neisseria meningitidis FAM18 hypothetical protein YP_974883.1 814991 R 272831 CDS YP_974884.1 121634639 4675515 complement(815285..815653) 1 NC_008767.1 hypothetical protein 815653 4675515 NMC0805 Neisseria meningitidis FAM18 hypothetical protein YP_974884.1 815285 R 272831 CDS YP_974885.1 121634640 4675556 complement(815999..816394) 1 NC_008767.1 hypothetical protein 816394 4675556 NMC0806 Neisseria meningitidis FAM18 hypothetical protein YP_974885.1 815999 R 272831 CDS YP_974886.1 121634641 4675424 complement(816437..817306) 1 NC_008767.1 hypothetical protein 817306 4675424 NMC0807 Neisseria meningitidis FAM18 hypothetical protein YP_974886.1 816437 R 272831 CDS YP_974887.1 121634642 4675404 817471..818394 1 NC_008767.1 hypothetical protein 818394 4675404 NMC0808 Neisseria meningitidis FAM18 hypothetical protein YP_974887.1 817471 D 272831 CDS YP_974888.1 121634643 4675413 complement(818472..819113) 1 NC_008767.1 hypothetical protein 819113 4675413 NMC0809 Neisseria meningitidis FAM18 hypothetical protein YP_974888.1 818472 R 272831 CDS YP_974889.1 121634644 4675420 complement(819168..819959) 1 NC_008767.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 819959 4675420 NMC0810 Neisseria meningitidis FAM18 spermidine synthase YP_974889.1 819168 R 272831 CDS YP_974890.1 121634645 4675383 820452..821243 1 NC_008767.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 821243 panB 4675383 panB Neisseria meningitidis FAM18 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_974890.1 820452 D 272831 CDS YP_974891.1 121634646 4675973 821366..822202 1 NC_008767.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 822202 panC 4675973 panC Neisseria meningitidis FAM18 pantoate--beta-alanine ligase YP_974891.1 821366 D 272831 CDS YP_974892.1 121634647 4675974 822361..824211 1 NC_008767.1 hypothetical protein 824211 4675974 NMC0813 Neisseria meningitidis FAM18 hypothetical protein YP_974892.1 822361 D 272831 CDS YP_974893.1 121634648 4675380 824294..824932 1 NC_008767.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 824932 lolB 4675380 lolB Neisseria meningitidis FAM18 molecular chaperone LolB YP_974893.1 824294 D 272831 CDS YP_974894.1 121634649 4675392 824942..825787 1 NC_008767.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 825787 ipk 4675392 ipk Neisseria meningitidis FAM18 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_974894.1 824942 D 272831 CDS YP_974895.1 121634650 4675379 826205..827188 1 NC_008767.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 827188 prsA 4675379 prsA Neisseria meningitidis FAM18 ribose-phosphate pyrophosphokinase YP_974895.1 826205 D 272831 CDS YP_974896.1 121634651 4676028 827255..827827 1 NC_008767.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 827827 4676028 NMC0817 Neisseria meningitidis FAM18 50S ribosomal protein L25 YP_974896.1 827255 D 272831 CDS YP_974897.1 121634652 4675377 complement(827952..829121) 1 NC_008767.1 D-alanyl-D-alanine carboxypeptidase 829121 4675377 NMC0818 Neisseria meningitidis FAM18 D-alanyl-D-alanine carboxypeptidase YP_974897.1 827952 R 272831 CDS YP_974898.1 121634653 4675376 829269..830795 1 NC_008767.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 830795 ilvA 4675376 ilvA Neisseria meningitidis FAM18 threonine dehydratase YP_974898.1 829269 D 272831 CDS YP_974899.1 121634654 4676441 complement(830852..831925) 1 NC_008767.1 sulfate permease ATP-binding protein 831925 cysA 4676441 cysA Neisseria meningitidis FAM18 sulfate permease ATP-binding protein YP_974899.1 830852 R 272831 CDS YP_974900.1 121634655 4675813 complement(831922..832782) 1 NC_008767.1 sulfate permease inner membrane protein 832782 cysW 4675813 cysW Neisseria meningitidis FAM18 sulfate permease inner membrane protein YP_974900.1 831922 R 272831 CDS YP_974901.1 121634656 4675995 complement(833037..833873) 1 NC_008767.1 sulfate permease inner membrane protein 833873 cysU 4675995 cysU Neisseria meningitidis FAM18 sulfate permease inner membrane protein YP_974901.1 833037 R 272831 CDS YP_974902.1 121634657 4676020 834164..834496 1 NC_008767.1 hypothetical protein 834496 4676020 NMC0823 Neisseria meningitidis FAM18 hypothetical protein YP_974902.1 834164 D 272831 CDS YP_974903.1 121634658 4675365 834827..835336 1 NC_008767.1 hypothetical protein 835336 4675365 NMC0824 Neisseria meningitidis FAM18 hypothetical protein YP_974903.1 834827 D 272831 CDS YP_974904.1 121634659 4675296 complement(835908..836495) 1 NC_008767.1 superoxide dismutase 836495 sodB 4675296 sodB Neisseria meningitidis FAM18 superoxide dismutase YP_974904.1 835908 R 272831 CDS YP_974905.1 121634660 4675031 836658..838064 1 NC_008767.1 unwinds double stranded DNA; replicative DNA helicase 838064 dnaB 4675031 dnaB Neisseria meningitidis FAM18 replicative DNA helicase YP_974905.1 836658 D 272831 CDS YP_974906.1 121634661 4675940 838328..839047 1 NC_008767.1 hypothetical protein 839047 4675940 NMC0827 Neisseria meningitidis FAM18 hypothetical protein YP_974906.1 838328 D 272831 CDS YP_974907.1 121634662 4675293 839065..839682 1 NC_008767.1 hypothetical protein 839682 4675293 NMC0828 Neisseria meningitidis FAM18 hypothetical protein YP_974907.1 839065 D 272831 CDS YP_974908.1 121634663 4675289 839679..840620 1 NC_008767.1 hypothetical protein 840620 4675289 NMC0829 Neisseria meningitidis FAM18 hypothetical protein YP_974908.1 839679 D 272831 CDS YP_974909.1 121634664 4675288 840599..841198 1 NC_008767.1 hypothetical protein 841198 4675288 NMC0830 Neisseria meningitidis FAM18 hypothetical protein YP_974909.1 840599 D 272831 CDS YP_974910.1 121634665 4675285 841188..841676 1 NC_008767.1 pilin 841676 4675285 NMC0831 Neisseria meningitidis FAM18 pilin YP_974910.1 841188 D 272831 CDS YP_974911.1 121634666 4675283 complement(843353..843835) 1 NC_008767.1 hypothetical protein 843835 4675283 NMC0832 Neisseria meningitidis FAM18 hypothetical protein YP_974911.1 843353 R 272831 CDS YP_974912.1 121634667 4675279 843948..844430 1 NC_008767.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 844430 dut 4675279 dut Neisseria meningitidis FAM18 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_974912.1 843948 D 272831 CDS YP_974913.1 121634668 4675929 844506..845693 1 NC_008767.1 catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate; succinyldiaminopimelate transaminase 845693 4675929 NMC0834 Neisseria meningitidis FAM18 succinyldiaminopimelate transaminase YP_974913.1 844506 D 272831 CDS YP_974914.1 121634669 4675265 845955..846734 1 NC_008767.1 hypothetical protein 846734 4675265 NMC0835 Neisseria meningitidis FAM18 hypothetical protein YP_974914.1 845955 D 272831 CDS YP_974915.1 121634670 4675264 847266..848462 1 NC_008767.1 Phage integrase 848462 4675264 NMC0836 Neisseria meningitidis FAM18 Phage integrase YP_974915.1 847266 D 272831 CDS YP_974916.1 121634671 4675263 848617..848997 1 NC_008767.1 hypothetical protein 848997 4675263 NMC0837 Neisseria meningitidis FAM18 hypothetical protein YP_974916.1 848617 D 272831 CDS YP_974917.1 121634672 4675262 849043..849231 1 NC_008767.1 hypothetical protein 849231 4675262 NMC0838 Neisseria meningitidis FAM18 hypothetical protein YP_974917.1 849043 D 272831 CDS YP_974918.1 121634673 4675261 849556..849912 1 NC_008767.1 hypothetical protein 849912 4675261 NMC0839 Neisseria meningitidis FAM18 hypothetical protein YP_974918.1 849556 D 272831 CDS YP_974919.1 121634674 4675260 850780..851697 1 NC_008767.1 phage related protein 851697 4675260 NMC0840 Neisseria meningitidis FAM18 phage related protein YP_974919.1 850780 D 272831 CDS YP_974920.1 121634675 4675274 complement(851755..852039) 1 NC_008767.1 D-lactate dehydrogenase-like protein 852039 4675274 NMC0841 Neisseria meningitidis FAM18 D-lactate dehydrogenase-like protein YP_974920.1 851755 R 272831 CDS YP_974921.1 121634676 4675133 complement(852101..852292) 1 NC_008767.1 hypothetical protein 852292 4675133 NMC0842 Neisseria meningitidis FAM18 hypothetical protein YP_974921.1 852101 R 272831 CDS YP_974922.1 121634677 4675131 complement(852295..852588) 1 NC_008767.1 hypothetical protein 852588 4675131 NMC0843 Neisseria meningitidis FAM18 hypothetical protein YP_974922.1 852295 R 272831 CDS YP_974923.1 121634678 4675130 complement(852585..852845) 1 NC_008767.1 coiled coil, 39-60; lipoprotein 852845 4675130 NMC0844 Neisseria meningitidis FAM18 lipoprotein YP_974923.1 852585 R 272831 CDS YP_974924.1 121634679 4675126 complement(852881..853096) 1 NC_008767.1 hypothetical protein 853096 4675126 NMC0845 Neisseria meningitidis FAM18 hypothetical protein YP_974924.1 852881 R 272831 CDS YP_974925.1 121634680 4675125 complement(853168..854022) 1 NC_008767.1 hypothetical protein 854022 4675125 NMC0846 Neisseria meningitidis FAM18 hypothetical protein YP_974925.1 853168 R 272831 CDS YP_974926.1 121634681 4675122 complement(854047..854406) 1 NC_008767.1 hypothetical protein 854406 4675122 NMC0847 Neisseria meningitidis FAM18 hypothetical protein YP_974926.1 854047 R 272831 CDS YP_974927.1 121634682 4675119 complement(854474..854674) 1 NC_008767.1 hypothetical protein 854674 4675119 NMC0848 Neisseria meningitidis FAM18 hypothetical protein YP_974927.1 854474 R 272831 CDS YP_974928.1 121634683 4675071 complement(854905..855429) 1 NC_008767.1 hypothetical protein 855429 4675071 NMC0849 Neisseria meningitidis FAM18 hypothetical protein YP_974928.1 854905 R 272831 CDS YP_974929.1 121634684 4675069 complement(855433..856149) 1 NC_008767.1 transcriptional regulator 856149 4675069 NMC0850 Neisseria meningitidis FAM18 transcriptional regulator YP_974929.1 855433 R 272831 CDS YP_974930.1 121634685 4675066 856549..856896 1 NC_008767.1 coiled coil, 56-83; hypothetical protein 856896 4675066 NMC0852 Neisseria meningitidis FAM18 hypothetical protein YP_974930.1 856549 D 272831 CDS YP_974931.1 121634686 4675065 857011..859857 1 NC_008767.1 hypothetical protein 859857 4675065 NMC0853 Neisseria meningitidis FAM18 hypothetical protein YP_974931.1 857011 D 272831 CDS YP_974932.1 121634687 4675054 859874..860083 1 NC_008767.1 hypothetical protein 860083 4675054 NMC0854 Neisseria meningitidis FAM18 hypothetical protein YP_974932.1 859874 D 272831 CDS YP_974933.1 121634688 4675048 860086..860472 1 NC_008767.1 hypothetical protein 860472 4675048 NMC0855 Neisseria meningitidis FAM18 hypothetical protein YP_974933.1 860086 D 272831 CDS YP_974934.1 121634689 4675041 860459..860713 1 NC_008767.1 coiled coil, 50-61; hypothetical protein 860713 4675041 NMC0856 Neisseria meningitidis FAM18 hypothetical protein YP_974934.1 860459 D 272831 CDS YP_974935.1 121634690 4675027 860722..862284 1 NC_008767.1 phage related protein 862284 4675027 NMC0857 Neisseria meningitidis FAM18 phage related protein YP_974935.1 860722 D 272831 CDS YP_974936.1 121634691 4674916 862274..864157 1 NC_008767.1 phage-like protein 864157 4674916 NMC0858 Neisseria meningitidis FAM18 phage-like protein YP_974936.1 862274 D 272831 CDS YP_974937.1 121634692 4674910 864215..864442 1 NC_008767.1 hypothetical protein 864442 4674910 NMC0859 Neisseria meningitidis FAM18 hypothetical protein YP_974937.1 864215 D 272831 CDS YP_974938.1 121634693 4674906 864435..864737 1 NC_008767.1 hypothetical protein 864737 4674906 NMC0860 Neisseria meningitidis FAM18 hypothetical protein YP_974938.1 864435 D 272831 CDS YP_974939.1 121634694 4674893 864760..865137 1 NC_008767.1 hypothetical protein 865137 4674893 NMC0861 Neisseria meningitidis FAM18 hypothetical protein YP_974939.1 864760 D 272831 CDS YP_974940.1 121634695 4674884 865169..865810 1 NC_008767.1 hypothetical protein 865810 4674884 NMC0862 Neisseria meningitidis FAM18 hypothetical protein YP_974940.1 865169 D 272831 CDS YP_974941.1 121634696 4674882 865874..866185 1 NC_008767.1 hypothetical protein 866185 4674882 NMC0863 Neisseria meningitidis FAM18 hypothetical protein YP_974941.1 865874 D 272831 CDS YP_974942.1 121634697 4674873 866233..866505 1 NC_008767.1 hypothetical protein 866505 4674873 NMC0864 Neisseria meningitidis FAM18 hypothetical protein YP_974942.1 866233 D 272831 CDS YP_974943.1 121634698 4674840 866498..869716 1 NC_008767.1 coiled coils, 60-70, 429-480, 760-775; prophage-like protein 869716 4674840 NMC0865 Neisseria meningitidis FAM18 prophage-like protein YP_974943.1 866498 D 272831 CDS YP_974944.1 121634699 4674830 869738..870007 1 NC_008767.1 phage-like protein 870007 4674830 NMC0866 Neisseria meningitidis FAM18 phage-like protein YP_974944.1 869738 D 272831 CDS YP_974945.1 121634700 4674794 870067..870789 1 NC_008767.1 phage-like protein 870789 4674794 NMC0867 Neisseria meningitidis FAM18 phage-like protein YP_974945.1 870067 D 272831 CDS YP_974946.1 121634701 4674765 870786..871541 1 NC_008767.1 phage-like protein NLPC_P60 871541 4674765 NMC0868 Neisseria meningitidis FAM18 phage-like protein NLPC_P60 YP_974946.1 870786 D 272831 CDS YP_974947.1 121634702 4676698 871538..872260 1 NC_008767.1 phage-like protein 872260 4676698 NMC0869 Neisseria meningitidis FAM18 phage-like protein YP_974947.1 871538 D 272831 CDS YP_974948.1 121634703 4675159 872396..876661 1 NC_008767.1 coiled coils, 800-880, 1120-1146; hypothetical protein 876661 4675159 NMC0870 Neisseria meningitidis FAM18 hypothetical protein YP_974948.1 872396 D 272831 CDS YP_974949.1 121634704 4675164 876732..877178 1 NC_008767.1 hypothetical protein 877178 4675164 NMC0871 Neisseria meningitidis FAM18 hypothetical protein YP_974949.1 876732 D 272831 CDS YP_974950.1 121634705 4675177 877195..877401 1 NC_008767.1 hypothetical protein 877401 4675177 NMC0872 Neisseria meningitidis FAM18 hypothetical protein YP_974950.1 877195 D 272831 CDS YP_974951.1 121634706 4675181 877430..877840 1 NC_008767.1 hypothetical protein 877840 4675181 NMC0873 Neisseria meningitidis FAM18 hypothetical protein YP_974951.1 877430 D 272831 CDS YP_974952.1 121634707 4675175 878740..879213 1 NC_008767.1 ATP binding protein 879213 4675175 NMC0877 Neisseria meningitidis FAM18 ATP binding protein YP_974952.1 878740 D 272831 CDS YP_974953.1 121634708 4674757 879225..879734 1 NC_008767.1 coiled coil, 60-100; hypothetical protein 879734 4674757 NMC0878 Neisseria meningitidis FAM18 hypothetical protein YP_974953.1 879225 D 272831 CDS YP_974954.1 121634709 4675234 complement(879787..880134) 1 NC_008767.1 plamid toxin PemK protein 880134 4675234 NMC0879 Neisseria meningitidis FAM18 plamid toxin PemK protein YP_974954.1 879787 R 272831 CDS YP_974955.1 121634710 4675443 complement(880136..880372) 1 NC_008767.1 transcriptional regulator 880372 4675443 NMC0880 Neisseria meningitidis FAM18 transcriptional regulator YP_974955.1 880136 R 272831 CDS YP_974956.1 121634711 4675359 complement(880731..881381) 1 NC_008767.1 hypothetical protein 881381 4675359 NMC0881 Neisseria meningitidis FAM18 hypothetical protein YP_974956.1 880731 R 272831 CDS YP_974957.1 121634712 4675232 complement(881660..882028) 1 NC_008767.1 death-on-curing protein, prophage related protein 882028 4675232 NMC0882 Neisseria meningitidis FAM18 death-on-curing protein, prophage related protein YP_974957.1 881660 R 272831 CDS YP_974958.1 121634713 4675233 complement(882025..882183) 1 NC_008767.1 hypothetical protein 882183 4675233 NMC0883 Neisseria meningitidis FAM18 hypothetical protein YP_974958.1 882025 R 272831 CDS YP_974959.1 121634714 4675136 complement(882572..883579) 1 NC_008767.1 transposase for IS1106A3 883579 4675136 NMC0884 Neisseria meningitidis FAM18 transposase for IS1106A3 YP_974959.1 882572 R 272831 CDS YP_974960.1 121634715 4675235 complement(884729..885991) 1 NC_008767.1 HlyD family secretion protein 885991 4675235 NMC0887 Neisseria meningitidis FAM18 HlyD family secretion protein YP_974960.1 884729 R 272831 CDS YP_974961.1 121634716 4675237 complement(885993..888089) 1 NC_008767.1 ABC transporter 888089 4675237 NMC0888 Neisseria meningitidis FAM18 ABC transporter YP_974961.1 885993 R 272831 CDS YP_974962.1 121634717 4675251 complement(888125..888460) 1 NC_008767.1 hypothetical protein 888460 4675251 NMC0889 Neisseria meningitidis FAM18 hypothetical protein YP_974962.1 888125 R 272831 CDS YP_974963.1 121634718 4675250 complement(888453..888872) 1 NC_008767.1 hypothetical protein 888872 4675250 NMC0890 Neisseria meningitidis FAM18 hypothetical protein YP_974963.1 888453 R 272831 CDS YP_974964.1 121634719 4676065 complement(888876..890024) 1 NC_008767.1 hypothetical protein 890024 4676065 NMC0891 Neisseria meningitidis FAM18 hypothetical protein YP_974964.1 888876 R 272831 CDS YP_974965.1 121634720 4675243 890118..890234 1 NC_008767.1 hypothetical protein 890234 4675243 NMC0892 Neisseria meningitidis FAM18 hypothetical protein YP_974965.1 890118 D 272831 CDS YP_974966.1 121634721 4676056 complement(890200..890403) 1 NC_008767.1 ParB protein 890403 4676056 NMC0893 Neisseria meningitidis FAM18 ParB protein YP_974966.1 890200 R 272831 CDS YP_974967.1 121634722 4675299 complement(join(890446..890865,890869..891090)) 1 NC_008767.1 ParA protein 891090 parA 4675299 parA Neisseria meningitidis FAM18 ParA protein YP_974967.1 890446 R 272831 CDS YP_974968.1 121634723 4676180 complement(891437..892411) 1 NC_008767.1 fragment due to substitution of M->S; transposase for IS1106A3 (fragment) 892411 4676180 NMC0896 Neisseria meningitidis FAM18 transposase for IS1106A3 (fragment) YP_974968.1 891437 R 272831 CDS YP_974969.1 121634724 4675242 complement(893798..896023) 1 NC_008767.1 isocitrate dehydrogenase 896023 icd 4675242 icd Neisseria meningitidis FAM18 isocitrate dehydrogenase YP_974969.1 893798 R 272831 CDS YP_974970.1 121634725 4676410 896456..897571 1 NC_008767.1 CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 897571 lst 4676410 lst Neisseria meningitidis FAM18 CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase YP_974970.1 896456 D 272831 CDS YP_974971.1 121634726 4676338 complement(897736..898194) 1 NC_008767.1 cytochrome C 898194 4676338 NMC0900 Neisseria meningitidis FAM18 cytochrome C YP_974971.1 897736 R 272831 CDS YP_974972.1 121634727 4676128 898313..899134 1 NC_008767.1 oxidoreductase 899134 4676128 NMC0901 Neisseria meningitidis FAM18 oxidoreductase YP_974972.1 898313 D 272831 CDS YP_974973.1 121634728 4675239 complement(899185..899631) 1 NC_008767.1 acyl-CoA hydrolase 899631 4675239 NMC0902 Neisseria meningitidis FAM18 acyl-CoA hydrolase YP_974973.1 899185 R 272831 CDS YP_974974.1 121634729 4675311 complement(join(901047..901790,901786..901833)) 1 NC_008767.1 hypothetical protein 901833 opaD 4675311 opaD Neisseria meningitidis FAM18 hypothetical protein YP_974974.1 901047 R 272831 CDS YP_974975.1 121634730 4675537 complement(902518..903483) 1 NC_008767.1 transposase for IS1655 903483 4675537 NMC0904 Neisseria meningitidis FAM18 transposase for IS1655 YP_974975.1 902518 R 272831 CDS YP_974976.1 121634731 4675315 904126..905061 1 NC_008767.1 proline iminopeptidase 905061 pip 4675315 pip Neisseria meningitidis FAM18 proline iminopeptidase YP_974976.1 904126 D 272831 CDS YP_974977.1 121634732 4676089 complement(905118..906314) 1 NC_008767.1 lipoprotein 906314 4676089 NMC0906 Neisseria meningitidis FAM18 lipoprotein YP_974977.1 905118 R 272831 CDS YP_974978.1 121634733 4675313 complement(906323..907198) 1 NC_008767.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 907198 dapA 4675313 dapA Neisseria meningitidis FAM18 dihydrodipicolinate synthase YP_974978.1 906323 R 272831 CDS YP_974979.1 121634734 4675949 907487..908896 1 NC_008767.1 transmembrane transport protein 908896 4675949 NMC0908 Neisseria meningitidis FAM18 transmembrane transport protein YP_974979.1 907487 D 272831 CDS YP_974980.1 121634735 4675324 complement(908958..909710) 1 NC_008767.1 RNA methylase 909710 4675324 NMC0909 Neisseria meningitidis FAM18 RNA methylase YP_974980.1 908958 R 272831 CDS YP_974981.1 121634736 4675323 complement(909776..910264) 1 NC_008767.1 hypothetical protein 910264 4675323 NMC0910 Neisseria meningitidis FAM18 hypothetical protein YP_974981.1 909776 R 272831 CDS YP_974982.1 121634737 4675318 complement(910269..910988) 1 NC_008767.1 cytosine deaminase 910988 4675318 NMC0911 Neisseria meningitidis FAM18 cytosine deaminase YP_974982.1 910269 R 272831 CDS YP_974983.1 121634738 4675325 complement(910992..911933) 1 NC_008767.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 911933 miaA 4675325 miaA Neisseria meningitidis FAM18 tRNA delta(2)-isopentenylpyrophosphate transferase YP_974983.1 910992 R 272831 CDS YP_974984.1 121634739 4676305 complement(join(912312..912875,912879..913685)) 1 NC_008767.1 hypothetical protein 913685 4676305 NMC0913 Neisseria meningitidis FAM18 hypothetical protein YP_974984.1 912312 R 272831 CDS YP_974985.1 121634740 4675320 913923..914483 1 NC_008767.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 914483 efp 4675320 efp Neisseria meningitidis FAM18 elongation factor P YP_974985.1 913923 D 272831 CDS YP_974986.1 121634741 4675921 complement(914533..915378) 1 NC_008767.1 lipoprotein 915378 4675921 NMC0916 Neisseria meningitidis FAM18 lipoprotein YP_974986.1 914533 R 272831 CDS YP_974987.1 121634742 4675287 complement(915495..916085) 1 NC_008767.1 hypothetical protein 916085 4675287 NMC0917 Neisseria meningitidis FAM18 hypothetical protein YP_974987.1 915495 R 272831 CDS YP_974988.1 121634743 4675326 complement(916073..917194) 1 NC_008767.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 917194 metX 4675326 metX Neisseria meningitidis FAM18 homoserine O-acetyltransferase YP_974988.1 916073 R 272831 CDS YP_974989.1 121634744 4676316 complement(917661..917786) 1 NC_008767.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 917786 rpmJ 4676316 rpmJ Neisseria meningitidis FAM18 50S ribosomal protein L36 YP_974989.1 917661 R 272831 CDS YP_974990.1 121634745 4675329 complement(917786..918061) 1 NC_008767.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 918061 rpmE2 4675329 rpmE2 Neisseria meningitidis FAM18 50S ribosomal protein L31 YP_974990.1 917786 R 272831 CDS YP_974991.1 121634746 4675430 918261..919139 1 NC_008767.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 919139 metF 4675430 metF Neisseria meningitidis FAM18 5,10-methylenetetrahydrofolate reductase YP_974991.1 918261 D 272831 CDS YP_974992.1 121634747 4676314 919277..921553 1 NC_008767.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 921553 metE 4676314 metE Neisseria meningitidis FAM18 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_974992.1 919277 D 272831 CDS YP_974993.1 121634748 4676313 921832..922569 1 NC_008767.1 redoxin 922569 4676313 NMC0923 Neisseria meningitidis FAM18 redoxin YP_974993.1 921832 D 272831 CDS YP_974994.1 121634749 4675333 922818..924221 1 NC_008767.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 924221 lpdA2 4675333 lpdA2 Neisseria meningitidis FAM18 dihydrolipoamide dehydrogenase YP_974994.1 922818 D 272831 CDS YP_974995.1 121634750 4676357 924500..924877 1 NC_008767.1 succinate dehydrogenase cytochrome B subunit 924877 sdhC 4676357 sdhC Neisseria meningitidis FAM18 succinate dehydrogenase cytochrome B subunit YP_974995.1 924500 D 272831 CDS YP_974996.1 121634751 4675110 924886..925212 1 NC_008767.1 succinate dehydrogenase hydrophobic membrane anchor protein 925212 sdhD 4675110 sdhD Neisseria meningitidis FAM18 succinate dehydrogenase hydrophobic membrane anchor protein YP_974996.1 924886 D 272831 CDS YP_974997.1 121634752 4675102 925203..926978 1 NC_008767.1 succinate dehydrogenase flavoprotein subunit 926978 sdhA 4675102 sdhA Neisseria meningitidis FAM18 succinate dehydrogenase flavoprotein subunit YP_974997.1 925203 D 272831 CDS YP_974998.1 121634753 4675217 927075..927806 1 NC_008767.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 927806 sdhB 4675217 sdhB Neisseria meningitidis FAM18 succinate dehydrogenase iron-sulfur subunit YP_974998.1 927075 D 272831 CDS YP_974999.1 121634754 4675109 927810..928058 1 NC_008767.1 hypothetical protein 928058 4675109 NMC0929 Neisseria meningitidis FAM18 hypothetical protein YP_974999.1 927810 D 272831 CDS YP_975000.1 121634755 4675331 928170..929453 1 NC_008767.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 929453 gltA 4675331 gltA Neisseria meningitidis FAM18 type II citrate synthase YP_975000.1 928170 D 272831 CDS YP_975001.1 121634756 4676576 929658..932486 1 NC_008767.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 932486 sucA 4676576 sucA Neisseria meningitidis FAM18 2-oxoglutarate dehydrogenase E1 YP_975001.1 929658 D 272831 CDS YP_975002.1 121634757 4675008 932586..933827 1 NC_008767.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 933827 sucB 4675008 sucB Neisseria meningitidis FAM18 dihydrolipoamide succinyltransferase YP_975002.1 932586 D 272831 CDS YP_975003.1 121634758 4674994 934192..935625 1 NC_008767.1 E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 935625 lpdA3 4674994 lpdA3 Neisseria meningitidis FAM18 dihydrolipoamide dehydrogenase YP_975003.1 934192 D 272831 CDS YP_975004.1 121634759 4676334 935750..936037 1 NC_008767.1 hypothetical protein 936037 4676334 NMC0934 Neisseria meningitidis FAM18 hypothetical protein YP_975004.1 935750 D 272831 CDS YP_975005.1 121634760 4675334 936137..937303 1 NC_008767.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 937303 sucC 4675334 sucC Neisseria meningitidis FAM18 succinyl-CoA synthetase subunit beta YP_975005.1 936137 D 272831 CDS YP_975006.1 121634761 4674995 937314..938204 1 NC_008767.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 938204 sucD 4674995 sucD Neisseria meningitidis FAM18 succinyl-CoA synthetase subunit alpha YP_975006.1 937314 D 272831 CDS YP_975007.1 121634762 4675209 complement(938439..938768) 1 NC_008767.1 hypothetical protein 938768 4675209 NMC0938 Neisseria meningitidis FAM18 hypothetical protein YP_975007.1 938439 R 272831 CDS YP_975008.1 121634763 4675336 complement(939748..941802) 1 NC_008767.1 low G+C; ATP-dependent helicase 941802 4675336 NMC0940 Neisseria meningitidis FAM18 ATP-dependent helicase YP_975008.1 939748 R 272831 CDS YP_975009.1 121634764 4675335 complement(941817..944663) 1 NC_008767.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 944663 uvrA 4675335 uvrA Neisseria meningitidis FAM18 excinuclease ABC subunit A YP_975009.1 941817 R 272831 CDS YP_975010.1 121634765 4676416 944818..945615 1 NC_008767.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 945615 4676416 NMC0942 Neisseria meningitidis FAM18 phosphatidylserine decarboxylase YP_975010.1 944818 D 272831 CDS YP_975011.1 121634766 4675339 complement(947278..949572) 1 NC_008767.1 outer-membrane receptor protein 949572 4675339 NMC0944 Neisseria meningitidis FAM18 outer-membrane receptor protein YP_975011.1 947278 R 272831 CDS YP_975012.1 121634767 4675340 949976..950566 1 NC_008767.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 950566 trpG 4675340 trpG Neisseria meningitidis FAM18 anthranilate synthase component II YP_975012.1 949976 D 272831 CDS YP_975013.1 121634768 4674813 950631..951689 1 NC_008767.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 951689 trpD 4674813 trpD Neisseria meningitidis FAM18 anthranilate phosphoribosyltransferase YP_975013.1 950631 D 272831 CDS YP_975014.1 121634769 4675188 complement(951841..952014) 1 NC_008767.1 transposase 952014 4675188 NMC0949 Neisseria meningitidis FAM18 transposase YP_975014.1 951841 R 272831 CDS YP_975015.1 121634770 4675338 952467..953501 1 NC_008767.1 phage replication initiation protein 953501 4675338 NMC0950 Neisseria meningitidis FAM18 phage replication initiation protein YP_975015.1 952467 D 272831 CDS YP_975016.1 121634771 4676283 953492..953836 1 NC_008767.1 hypothetical protein 953836 4676283 NMC0951 Neisseria meningitidis FAM18 hypothetical protein YP_975016.1 953492 D 272831 CDS YP_975017.1 121634772 4676099 953841..954038 1 NC_008767.1 hypothetical protein 954038 4676099 NMC0952 Neisseria meningitidis FAM18 hypothetical protein YP_975017.1 953841 D 272831 CDS YP_975018.1 121634773 4675345 954046..954330 1 NC_008767.1 hypothetical protein 954330 4675345 NMC0953 Neisseria meningitidis FAM18 hypothetical protein YP_975018.1 954046 D 272831 CDS YP_975019.1 121634774 4675156 954337..954615 1 NC_008767.1 hypothetical protein 954615 4675156 NMC0954 Neisseria meningitidis FAM18 hypothetical protein YP_975019.1 954337 D 272831 CDS YP_975020.1 121634775 4675148 954773..955060 1 NC_008767.1 hypothetical protein 955060 4675148 NMC0955 Neisseria meningitidis FAM18 hypothetical protein YP_975020.1 954773 D 272831 CDS YP_975021.1 121634776 4675346 955002..955442 1 NC_008767.1 cell-surface protein 955442 4675346 NMC0956 Neisseria meningitidis FAM18 cell-surface protein YP_975021.1 955002 D 272831 CDS YP_975022.1 121634777 4675435 955953..956513 1 NC_008767.1 hypothetical protein 956513 4675435 NMC0957 Neisseria meningitidis FAM18 hypothetical protein YP_975022.1 955953 D 272831 CDS YP_975023.1 121634778 4675444 complement(956721..958106) 1 NC_008767.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 958106 pntB 4675444 pntB Neisseria meningitidis FAM18 pyridine nucleotide transhydrogenase YP_975023.1 956721 R 272831 CDS YP_975024.1 121634779 4676095 complement(958172..958555) 1 NC_008767.1 hypothetical protein 958555 4676095 NMC0959 Neisseria meningitidis FAM18 hypothetical protein YP_975024.1 958172 R 272831 CDS YP_975025.1 121634780 4675449 complement(958559..960100) 1 NC_008767.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 960100 pntA 4675449 pntA Neisseria meningitidis FAM18 NAD(P) transhydrogenase subunit alpha YP_975025.1 958559 R 272831 CDS YP_975026.1 121634781 4676094 960393..961226 1 NC_008767.1 phosphoserine phosphatase 961226 serB 4676094 serB Neisseria meningitidis FAM18 phosphoserine phosphatase YP_975026.1 960393 D 272831 CDS YP_975027.1 121634782 4675092 961271..962512 1 NC_008767.1 hypothetical protein 962512 4675092 NMC0962 Neisseria meningitidis FAM18 hypothetical protein YP_975027.1 961271 D 272831 CDS YP_975028.1 121634783 4675448 962677..964257 1 NC_008767.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 964257 purH 4675448 purH Neisseria meningitidis FAM18 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_975028.1 962677 D 272831 CDS YP_975029.1 121634784 4675787 964856..965812 1 NC_008767.1 transposase 965812 4675787 NMC0964 Neisseria meningitidis FAM18 transposase YP_975029.1 964856 D 272831 CDS YP_975030.1 121634785 4675447 965966..966400 1 NC_008767.1 phage related protein 966400 4675447 NMC0965 Neisseria meningitidis FAM18 phage related protein YP_975030.1 965966 D 272831 CDS YP_975031.1 121634786 4675457 966372..966809 1 NC_008767.1 phage related protein 966809 4675457 NMC0966 Neisseria meningitidis FAM18 phage related protein YP_975031.1 966372 D 272831 CDS YP_975032.1 121634787 4675362 967117..967662 1 NC_008767.1 amidase 967662 4675362 NMC0967 Neisseria meningitidis FAM18 amidase YP_975032.1 967117 D 272831 CDS YP_975033.1 121634788 4675452 967895..968032 1 NC_008767.1 phage related protein 968032 4675452 NMC0969 Neisseria meningitidis FAM18 phage related protein YP_975033.1 967895 D 272831 CDS YP_975034.1 121634789 4675458 968035..968271 1 NC_008767.1 phage related protein 968271 4675458 NMC0970 Neisseria meningitidis FAM18 phage related protein YP_975034.1 968035 D 272831 CDS YP_975035.1 121634790 4675467 968252..968662 1 NC_008767.1 phage related protein 968662 4675467 NMC0971 Neisseria meningitidis FAM18 phage related protein YP_975035.1 968252 D 272831 CDS YP_975036.1 121634791 4675466 968706..968864 1 NC_008767.1 phage related protein 968864 4675466 NMC0972 Neisseria meningitidis FAM18 phage related protein YP_975036.1 968706 D 272831 CDS YP_975037.1 121634792 4675461 complement(968909..969079) 1 NC_008767.1 hypothetical protein 969079 4675461 NMC0973 Neisseria meningitidis FAM18 hypothetical protein YP_975037.1 968909 R 272831 CDS YP_975038.1 121634793 4675474 969092..969310 1 NC_008767.1 phage related protein 969310 4675474 NMC0974 Neisseria meningitidis FAM18 phage related protein YP_975038.1 969092 D 272831 CDS YP_975039.1 121634794 4675481 complement(969503..970468) 1 NC_008767.1 transposase for IS1655 970468 4675481 NMC0976 Neisseria meningitidis FAM18 transposase for IS1655 YP_975039.1 969503 R 272831 CDS YP_975040.1 121634795 4675477 complement(970767..971774) 1 NC_008767.1 transposase for IS1106 971774 4675477 NMC0977 Neisseria meningitidis FAM18 transposase for IS1106 YP_975040.1 970767 R 272831 CDS YP_975041.1 121634796 4675482 complement(971907..973676) 1 NC_008767.1 surface fibril protein 973676 4675482 NMC0978 Neisseria meningitidis FAM18 surface fibril protein YP_975041.1 971907 R 272831 CDS YP_975042.1 121634797 4675480 complement(975798..976004) 1 NC_008767.1 rubredoxin 976004 4675480 NMC0980 Neisseria meningitidis FAM18 rubredoxin YP_975042.1 975798 R 272831 CDS YP_975043.1 121634798 4675488 complement(976440..977531) 1 NC_008767.1 acyl-CoA dehydrogenase 977531 4675488 NMC0981 Neisseria meningitidis FAM18 acyl-CoA dehydrogenase YP_975043.1 976440 R 272831 CDS YP_975044.1 121634799 4675487 complement(977666..978349) 1 NC_008767.1 hypothetical protein 978349 4675487 NMC0982 Neisseria meningitidis FAM18 hypothetical protein YP_975044.1 977666 R 272831 CDS YP_975045.1 121634800 4675490 complement(978369..978740) 1 NC_008767.1 hypothetical protein 978740 4675490 NMC0983 Neisseria meningitidis FAM18 hypothetical protein YP_975045.1 978369 R 272831 CDS YP_975046.1 121634801 4675495 complement(979035..980726) 1 NC_008767.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 980726 dld 4675495 dld Neisseria meningitidis FAM18 D-lactate dehydrogenase YP_975046.1 979035 R 272831 CDS YP_975047.1 121634802 4675960 981164..985084 1 NC_008767.1 oxidoreductase 985084 4675960 NMC0985 Neisseria meningitidis FAM18 oxidoreductase YP_975047.1 981164 D 272831 CDS YP_975048.1 121634803 4675491 985137..986162 1 NC_008767.1 hypothetical protein 986162 4675491 NMC0986 Neisseria meningitidis FAM18 hypothetical protein YP_975048.1 985137 D 272831 CDS YP_975049.1 121634804 4675494 986593..987600 1 NC_008767.1 transposase for IS1106 987600 4675494 NMC0988 Neisseria meningitidis FAM18 transposase for IS1106 YP_975049.1 986593 D 272831 CDS YP_975050.1 121634805 4675513 complement(988668..989306) 1 NC_008767.1 phage integrase 989306 4675513 NMC0992 Neisseria meningitidis FAM18 phage integrase YP_975050.1 988668 R 272831 CDS YP_975051.1 121634806 4675528 complement(989615..990490) 1 NC_008767.1 hypothetical protein 990490 4675528 NMC0993 Neisseria meningitidis FAM18 hypothetical protein YP_975051.1 989615 R 272831 CDS YP_975052.1 121634807 4675512 complement(990535..990831) 1 NC_008767.1 hypothetical protein 990831 4675512 NMC0995 Neisseria meningitidis FAM18 hypothetical protein YP_975052.1 990535 R 272831 CDS YP_975053.1 121634808 4675582 991130..991507 1 NC_008767.1 phage repressor 991507 4675582 NMC0997 Neisseria meningitidis FAM18 phage repressor YP_975053.1 991130 D 272831 CDS YP_975054.1 121634809 4676364 991536..991781 1 NC_008767.1 hypothetical protein 991781 4676364 NMC0998 Neisseria meningitidis FAM18 hypothetical protein YP_975054.1 991536 D 272831 CDS YP_975055.1 121634810 4675510 991867..991959 1 NC_008767.1 hypothetical protein 991959 4675510 NMC0999 Neisseria meningitidis FAM18 hypothetical protein YP_975055.1 991867 D 272831 CDS YP_975056.1 121634811 4675521 992071..992982 1 NC_008767.1 hypothetical protein 992982 4675521 NMC1000 Neisseria meningitidis FAM18 hypothetical protein YP_975056.1 992071 D 272831 CDS YP_975057.1 121634812 4675588 992979..993461 1 NC_008767.1 hypothetical protein 993461 4675588 NMC1001 Neisseria meningitidis FAM18 hypothetical protein YP_975057.1 992979 D 272831 CDS YP_975058.1 121634813 4675585 993551..994054 1 NC_008767.1 hypothetical protein 994054 4675585 NMC1002 Neisseria meningitidis FAM18 hypothetical protein YP_975058.1 993551 D 272831 CDS YP_975059.1 121634814 4675596 994491..994901 1 NC_008767.1 hypothetical protein 994901 4675596 NMC1005 Neisseria meningitidis FAM18 hypothetical protein YP_975059.1 994491 D 272831 CDS YP_975060.1 121634815 4675589 994906..995655 1 NC_008767.1 transposase 995655 4675589 NMC1006 Neisseria meningitidis FAM18 transposase YP_975060.1 994906 D 272831 CDS YP_975061.1 121634816 4675605 complement(996397..997002) 1 NC_008767.1 hypothetical protein 997002 4675605 NMC1007 Neisseria meningitidis FAM18 hypothetical protein YP_975061.1 996397 R 272831 CDS YP_975062.1 121634817 4675603 complement(997069..998034) 1 NC_008767.1 transposase for IS1655 998034 4675603 NMC1008 Neisseria meningitidis FAM18 transposase for IS1655 YP_975062.1 997069 R 272831 CDS YP_975063.1 121634818 4675612 complement(998811..999866) 1 NC_008767.1 sulfate-binding protein 999866 4675612 NMC1009 Neisseria meningitidis FAM18 sulfate-binding protein YP_975063.1 998811 R 272831 CDS YP_975064.1 121634819 4675609 complement(999972..1000454) 1 NC_008767.1 hypothetical protein 1000454 4675609 NMC1010 Neisseria meningitidis FAM18 hypothetical protein YP_975064.1 999972 R 272831 CDS YP_975065.1 121634820 4675606 complement(1000501..1001637) 1 NC_008767.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1001637 purK 4675606 purK Neisseria meningitidis FAM18 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_975065.1 1000501 R 272831 CDS YP_975066.1 121634821 4675788 complement(1001634..1002179) 1 NC_008767.1 hypothetical protein 1002179 4675788 NMC1012 Neisseria meningitidis FAM18 hypothetical protein YP_975066.1 1001634 R 272831 CDS YP_975067.1 121634822 4675564 complement(1002176..1003651) 1 NC_008767.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1003651 trpE 4675564 trpE Neisseria meningitidis FAM18 anthranilate synthase component I YP_975067.1 1002176 R 272831 CDS YP_975068.1 121634823 4674827 complement(1003762..1004127) 1 NC_008767.1 hypothetical protein 1004127 4674827 NMC1014 Neisseria meningitidis FAM18 hypothetical protein YP_975068.1 1003762 R 272831 CDS YP_975069.1 121634824 4675615 complement(1004148..1006073) 1 NC_008767.1 ABC transporter ATP-binding protein 1006073 abcZ 4675615 abcZ Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975069.1 1004148 R 272831 CDS YP_975070.1 121634825 4676301 complement(1006077..1006721) 1 NC_008767.1 DedA protein ortholog 1006721 dedA 4676301 dedA Neisseria meningitidis FAM18 DedA protein ortholog YP_975070.1 1006077 R 272831 CDS YP_975071.1 121634826 4675931 complement(1006812..1008062) 1 NC_008767.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1008062 glyA 4675931 glyA Neisseria meningitidis FAM18 serine hydroxymethyltransferase YP_975071.1 1006812 R 272831 CDS YP_975072.1 121634827 4676575 complement(1008543..1010318) 1 NC_008767.1 gamma-glutamyltranspeptidase 1010318 ggt 4676575 ggt Neisseria meningitidis FAM18 gamma-glutamyltranspeptidase YP_975072.1 1008543 R 272831 CDS YP_975073.1 121634828 4676621 1010889..1011116 1 NC_008767.1 hypothetical protein 1011116 4676621 NMC1020 Neisseria meningitidis FAM18 hypothetical protein YP_975073.1 1010889 D 272831 CDS YP_975074.1 121634829 4675623 1011092..1011310 1 NC_008767.1 hypothetical protein 1011310 4675623 NMC1021 Neisseria meningitidis FAM18 hypothetical protein YP_975074.1 1011092 D 272831 CDS YP_975075.1 121634830 4675625 complement(1011469..1012443) 1 NC_008767.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1012443 fbp 4675625 fbp Neisseria meningitidis FAM18 fructose-1,6-bisphosphatase YP_975075.1 1011469 R 272831 CDS YP_975076.1 121634831 4675838 complement(1012689..1013534) 1 NC_008767.1 hypothetical protein 1013534 4675838 NMC1024 Neisseria meningitidis FAM18 hypothetical protein YP_975076.1 1012689 R 272831 CDS YP_975077.1 121634832 4675621 complement(1013622..1014224) 1 NC_008767.1 hypothetical protein 1014224 4675621 NMC1026 Neisseria meningitidis FAM18 hypothetical protein YP_975077.1 1013622 R 272831 CDS YP_975078.1 121634833 4675624 1014280..1014636 1 NC_008767.1 dihydroneopterin aldolase 1014636 folB 4675624 folB Neisseria meningitidis FAM18 dihydroneopterin aldolase YP_975078.1 1014280 D 272831 CDS YP_975079.1 121634834 4676704 1014670..1015206 1 NC_008767.1 hypothetical protein 1015206 4676704 NMC1028 Neisseria meningitidis FAM18 hypothetical protein YP_975079.1 1014670 D 272831 CDS YP_975080.1 121634835 4675622 complement(1016250..1016609) 1 NC_008767.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1016609 4675622 NMC1029 Neisseria meningitidis FAM18 camphor resistance protein CrcB YP_975080.1 1016250 R 272831 CDS YP_975081.1 121634836 4675636 complement(1016638..1017318) 1 NC_008767.1 hypothetical protein 1017318 4675636 NMC1030 Neisseria meningitidis FAM18 hypothetical protein YP_975081.1 1016638 R 272831 CDS YP_975082.1 121634837 4675568 1017483..1020515 1 NC_008767.1 cell-division protein 1020515 4675568 NMC1031 Neisseria meningitidis FAM18 cell-division protein YP_975082.1 1017483 D 272831 CDS YP_975083.1 121634838 4675630 complement(1020740..1022002) 1 NC_008767.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1022002 proA 4675630 proA Neisseria meningitidis FAM18 gamma-glutamyl phosphate reductase YP_975083.1 1020740 R 272831 CDS YP_975084.1 121634839 4676055 complement(1022015..1023124) 1 NC_008767.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1023124 proB 4676055 proB Neisseria meningitidis FAM18 gamma-glutamyl kinase YP_975084.1 1022015 R 272831 CDS YP_975085.1 121634840 4675871 1023610..1025163 1 NC_008767.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1025163 leuA 4675871 leuA Neisseria meningitidis FAM18 2-isopropylmalate synthase YP_975085.1 1023610 D 272831 CDS YP_975086.1 121634841 4676399 1025363..1026025 1 NC_008767.1 hypothetical protein 1026025 4676399 NMC1035 Neisseria meningitidis FAM18 hypothetical protein YP_975086.1 1025363 D 272831 CDS YP_975087.1 121634842 4675635 complement(1026108..1026959) 1 NC_008767.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1026959 lgt 4675635 lgt Neisseria meningitidis FAM18 prolipoprotein diacylglyceryl transferase YP_975087.1 1026108 R 272831 CDS YP_975088.1 121634843 4676389 complement(1027032..1028162) 1 NC_008767.1 hypothetical protein 1028162 4676389 NMC1037 Neisseria meningitidis FAM18 hypothetical protein YP_975088.1 1027032 R 272831 CDS YP_975089.1 121634844 4675627 1028332..1029228 1 NC_008767.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1029228 argB 4675627 argB Neisseria meningitidis FAM18 acetylglutamate kinase YP_975089.1 1028332 D 272831 CDS YP_975090.1 121634845 4676425 complement(1031085..1031753) 1 NC_008767.1 hypothetical protein 1031753 4676425 NMC1039 Neisseria meningitidis FAM18 hypothetical protein YP_975090.1 1031085 R 272831 CDS YP_975091.1 121634846 4676696 complement(1031750..1032481) 1 NC_008767.1 chromosome replication initiator DnaA 1032481 4676696 NMC1040 Neisseria meningitidis FAM18 chromosome replication initiator DnaA YP_975091.1 1031750 R 272831 CDS YP_975092.1 121634847 4676578 complement(1032523..1033140) 1 NC_008767.1 ABC transporter ATP-binding protein 1033140 4676578 NMC1041 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975092.1 1032523 R 272831 CDS YP_975093.1 121634848 4675835 1033116..1033295 1 NC_008767.1 hypothetical protein 1033295 4675835 NMC1042 Neisseria meningitidis FAM18 hypothetical protein YP_975093.1 1033116 D 272831 CDS YP_975094.1 121634849 4675657 complement(1033495..1034394) 1 NC_008767.1 DNA-binding protein 1034394 4675657 NMC1044 Neisseria meningitidis FAM18 DNA-binding protein YP_975094.1 1033495 R 272831 CDS YP_975095.1 121634850 4676551 1034438..1034689 1 NC_008767.1 DNA-binding protein (phage related) 1034689 4676551 NMC1045 Neisseria meningitidis FAM18 DNA-binding protein (phage related) YP_975095.1 1034438 D 272831 CDS YP_975096.1 121634851 4675736 1034691..1036670 1 NC_008767.1 phage transposase 1036670 4675736 NMC1046 Neisseria meningitidis FAM18 phage transposase YP_975096.1 1034691 D 272831 CDS YP_975097.1 121634852 4675817 1036706..1037620 1 NC_008767.1 phage transposase 1037620 4675817 NMC1048 Neisseria meningitidis FAM18 phage transposase YP_975097.1 1036706 D 272831 CDS YP_975098.1 121634853 4675729 1037686..1037976 1 NC_008767.1 hypothetical protein 1037976 4675729 NMC1049 Neisseria meningitidis FAM18 hypothetical protein YP_975098.1 1037686 D 272831 CDS YP_975099.1 121634854 4675728 1037963..1038088 1 NC_008767.1 hypothetical protein 1038088 4675728 NMC1050 Neisseria meningitidis FAM18 hypothetical protein YP_975099.1 1037963 D 272831 CDS YP_975100.1 121634855 4675738 1038085..1038258 1 NC_008767.1 hypothetical protein 1038258 4675738 NMC1051 Neisseria meningitidis FAM18 hypothetical protein YP_975100.1 1038085 D 272831 CDS YP_975101.1 121634856 4675742 1038251..1038418 1 NC_008767.1 hypothetical protein 1038418 4675742 NMC1052 Neisseria meningitidis FAM18 hypothetical protein YP_975101.1 1038251 D 272831 CDS YP_975102.1 121634857 4675739 1038482..1038709 1 NC_008767.1 hypothetical protein 1038709 4675739 NMC1053 Neisseria meningitidis FAM18 hypothetical protein YP_975102.1 1038482 D 272831 CDS YP_975103.1 121634858 4675752 1038724..1039242 1 NC_008767.1 host-nuclease inhibitor protein 1039242 gam 4675752 gam Neisseria meningitidis FAM18 host-nuclease inhibitor protein YP_975103.1 1038724 D 272831 CDS YP_975104.1 121634859 4676630 complement(1039375..1040340) 1 NC_008767.1 transposase for IS1655 1040340 4676630 NMC1055 Neisseria meningitidis FAM18 transposase for IS1655 YP_975104.1 1039375 R 272831 CDS YP_975105.1 121634860 4675759 1041177..1041737 1 NC_008767.1 hypothetical protein 1041737 4675759 NMC1057 Neisseria meningitidis FAM18 hypothetical protein YP_975105.1 1041177 D 272831 CDS YP_975106.1 121634861 4675770 1041748..1043721 1 NC_008767.1 phage tail fiber protein 1043721 4675770 NMC1058 Neisseria meningitidis FAM18 phage tail fiber protein YP_975106.1 1041748 D 272831 CDS YP_975107.1 121634862 4675765 1045258..1045863 1 NC_008767.1 hypothetical protein 1045863 4675765 NMC1059 Neisseria meningitidis FAM18 hypothetical protein YP_975107.1 1045258 D 272831 CDS YP_975108.1 121634863 4675786 1045842..1046138 1 NC_008767.1 hypothetical protein 1046138 4675786 NMC1060 Neisseria meningitidis FAM18 hypothetical protein YP_975108.1 1045842 D 272831 CDS YP_975109.1 121634864 4675800 complement(join(1046454..1047416,1047418..1047597)) 1 NC_008767.1 ABC transporter ATP-binding protein 1047597 4675800 NMC1062 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975109.1 1046454 R 272831 CDS YP_975110.1 121634865 4675773 complement(1048039..1048686) 1 NC_008767.1 hypothetical protein 1048686 4675773 NMC1063 Neisseria meningitidis FAM18 hypothetical protein YP_975110.1 1048039 R 272831 CDS YP_975111.1 121634866 4675796 complement(1048683..1049054) 1 NC_008767.1 hypothetical protein 1049054 4675796 NMC1065 Neisseria meningitidis FAM18 hypothetical protein YP_975111.1 1048683 R 272831 CDS YP_975112.1 121634867 4675785 complement(1049061..1049732) 1 NC_008767.1 hypothetical protein 1049732 4675785 NMC1066 Neisseria meningitidis FAM18 hypothetical protein YP_975112.1 1049061 R 272831 CDS YP_975113.1 121634868 4675801 complement(1049897..1050616) 1 NC_008767.1 short chain dehydrogenase 1050616 4675801 NMC1067 Neisseria meningitidis FAM18 short chain dehydrogenase YP_975113.1 1049897 R 272831 CDS YP_975114.1 121634869 4675805 complement(1050699..1052012) 1 NC_008767.1 oxidoreductase 1052012 4675805 NMC1068 Neisseria meningitidis FAM18 oxidoreductase YP_975114.1 1050699 R 272831 CDS YP_975115.1 121634870 4675803 complement(1052409..1053281) 1 NC_008767.1 poly-isoprenyl transferase 1053281 4675803 NMC1069 Neisseria meningitidis FAM18 poly-isoprenyl transferase YP_975115.1 1052409 R 272831 CDS YP_975116.1 121634871 4675802 1053296..1055314 1 NC_008767.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 1055314 hscA 4675802 hscA Neisseria meningitidis FAM18 chaperone protein HscA YP_975116.1 1053296 D 272831 CDS YP_975117.1 121634872 4675806 1055637..1056200 1 NC_008767.1 hypothetical protein 1056200 4675806 NMC1071 Neisseria meningitidis FAM18 hypothetical protein YP_975117.1 1055637 D 272831 CDS YP_975118.1 121634873 4675810 1056483..1056998 1 NC_008767.1 hypothetical protein 1056998 4675810 NMC1072 Neisseria meningitidis FAM18 hypothetical protein YP_975118.1 1056483 D 272831 CDS YP_975119.1 121634874 4675809 1057053..1057394 1 NC_008767.1 ferredoxin 1057394 fdx 4675809 fdx Neisseria meningitidis FAM18 ferredoxin YP_975119.1 1057053 D 272831 CDS YP_975120.1 121634875 4675854 complement(1057681..1058268) 1 NC_008767.1 hypothetical protein 1058268 4675854 NMC1074 Neisseria meningitidis FAM18 hypothetical protein YP_975120.1 1057681 R 272831 CDS YP_975121.1 121634876 4675821 1058481..1058678 1 NC_008767.1 hypothetical protein 1058678 4675821 NMC1076 Neisseria meningitidis FAM18 hypothetical protein YP_975121.1 1058481 D 272831 CDS YP_975122.1 121634877 4675811 complement(1058746..1059147) 1 NC_008767.1 hypothetical protein 1059147 4675811 NMC1077 Neisseria meningitidis FAM18 hypothetical protein YP_975122.1 1058746 R 272831 CDS YP_975123.1 121634878 4675827 1059358..1060317 1 NC_008767.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1060317 accA 4675827 accA Neisseria meningitidis FAM18 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_975123.1 1059358 D 272831 CDS YP_975124.1 121634879 4676302 1060358..1061695 1 NC_008767.1 hypothetical protein 1061695 4676302 NMC1080 Neisseria meningitidis FAM18 hypothetical protein YP_975124.1 1060358 D 272831 CDS YP_975125.1 121634880 4675822 1061769..1062554 1 NC_008767.1 RNA methyltransferase 1062554 4675822 NMC1081 Neisseria meningitidis FAM18 RNA methyltransferase YP_975125.1 1061769 D 272831 CDS YP_975126.1 121634881 4676003 1062605..1062841 1 NC_008767.1 lipoprotein 1062841 4676003 NMC1082 Neisseria meningitidis FAM18 lipoprotein YP_975126.1 1062605 D 272831 CDS YP_975127.1 121634882 4675818 1063023..1063376 1 NC_008767.1 hypothetical protein 1063376 4675818 NMC1083 Neisseria meningitidis FAM18 hypothetical protein YP_975127.1 1063023 D 272831 CDS YP_975128.1 121634883 4676016 1063388..1063693 1 NC_008767.1 hypothetical protein 1063693 4676016 NMC1084 Neisseria meningitidis FAM18 hypothetical protein YP_975128.1 1063388 D 272831 CDS YP_975129.1 121634884 4675990 1063755..1065131 1 NC_008767.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso- diaminopimelate ligase 1065131 mpl 4675990 mpl Neisseria meningitidis FAM18 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso- diaminopimelate ligase YP_975129.1 1063755 D 272831 CDS YP_975130.1 121634885 4676286 1065140..1066390 1 NC_008767.1 biotin synthase 1066390 bioB 4676286 bioB Neisseria meningitidis FAM18 biotin synthase YP_975130.1 1065140 D 272831 CDS YP_975131.1 121634886 4676627 complement(1066374..1067102) 1 NC_008767.1 hypothetical protein 1067102 4676627 NMC1088 Neisseria meningitidis FAM18 hypothetical protein YP_975131.1 1066374 R 272831 CDS YP_975132.1 121634887 4675879 complement(1067226..1067465) 1 NC_008767.1 hypothetical protein 1067465 4675879 NMC1089 Neisseria meningitidis FAM18 hypothetical protein YP_975132.1 1067226 R 272831 CDS YP_975133.1 121634888 4675932 complement(1067748..1069607) 1 NC_008767.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1069607 ilvD 4675932 ilvD Neisseria meningitidis FAM18 dihydroxy-acid dehydratase YP_975133.1 1067748 R 272831 CDS YP_975134.1 121634889 4676437 complement(1069780..1071549) 1 NC_008767.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 1071549 cysI 4676437 cysI Neisseria meningitidis FAM18 sulfite reductase subunit beta YP_975134.1 1069780 R 272831 CDS YP_975135.1 121634890 4675744 complement(1071576..1073390) 1 NC_008767.1 sulfite reductase subunit alpha 1073390 cysJ 4675744 cysJ Neisseria meningitidis FAM18 sulfite reductase subunit alpha YP_975135.1 1071576 R 272831 CDS YP_975136.1 121634891 4675745 complement(1073387..1074673) 1 NC_008767.1 sulfate adenylate transferase subunit 1 1074673 cysN 4675745 cysN Neisseria meningitidis FAM18 sulfate adenylate transferase subunit 1 YP_975136.1 1073387 R 272831 CDS YP_975137.1 121634892 4676022 complement(1074712..1075635) 1 NC_008767.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 1075635 cysD 4676022 cysD Neisseria meningitidis FAM18 sulfate adenylyltransferase subunit 2 YP_975137.1 1074712 R 272831 CDS YP_975138.1 121634893 4675631 complement(1075673..1076407) 1 NC_008767.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 1076407 cysH 4675631 cysH Neisseria meningitidis FAM18 phosphoadenosine phosphosulfate reductase YP_975138.1 1075673 R 272831 CDS YP_975139.1 121634894 4675846 complement(1076423..1077874) 1 NC_008767.1 siroheme synthase 1077874 cysG 4675846 cysG Neisseria meningitidis FAM18 siroheme synthase YP_975139.1 1076423 R 272831 CDS YP_975140.1 121634895 4675845 complement(1078324..1078980) 1 NC_008767.1 hypothetical protein 1078980 4675845 NMC1097 Neisseria meningitidis FAM18 hypothetical protein YP_975140.1 1078324 R 272831 CDS YP_975141.1 121634896 4675163 1079045..1079935 1 NC_008767.1 hypothetical protein 1079935 4675163 NMC1098 Neisseria meningitidis FAM18 hypothetical protein YP_975141.1 1079045 D 272831 CDS YP_975142.1 121634897 4675927 1080205..1082016 1 NC_008767.1 GTP-binding protein 1082016 typA 4675927 typA Neisseria meningitidis FAM18 GTP-binding protein YP_975142.1 1080205 D 272831 CDS YP_975143.1 121634898 4674750 1083004..1085379 1 NC_008767.1 ribonuclease 1085379 vacB 4674750 vacB Neisseria meningitidis FAM18 ribonuclease YP_975143.1 1083004 D 272831 CDS YP_975144.1 121634899 4676712 complement(1085718..1087181) 1 NC_008767.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 1087181 guaB 4676712 guaB Neisseria meningitidis FAM18 inosine 5'-monophosphate dehydrogenase YP_975144.1 1085718 R 272831 CDS YP_975145.1 121634900 4676490 complement(1087328..1089886) 1 NC_008767.1 [protein-PII] uridylyltransferase 1089886 glnD 4676490 glnD Neisseria meningitidis FAM18 [protein-PII] uridylyltransferase YP_975145.1 1087328 R 272831 CDS YP_975146.1 121634901 4676609 complement(1089935..1090255) 1 NC_008767.1 transcriptional regulator 1090255 4676609 NMC1106 Neisseria meningitidis FAM18 transcriptional regulator YP_975146.1 1089935 R 272831 CDS YP_975147.1 121634902 4675912 complement(1090579..1091052) 1 NC_008767.1 bacterioferritin B 1091052 bfrB 4675912 bfrB Neisseria meningitidis FAM18 bacterioferritin B YP_975147.1 1090579 R 272831 CDS YP_975148.1 121634903 4676570 complement(1091080..1091544) 1 NC_008767.1 bacterioferritin A 1091544 bfrA 4676570 bfrA Neisseria meningitidis FAM18 bacterioferritin A YP_975148.1 1091080 R 272831 CDS YP_975149.1 121634904 4676569 complement(1092007..1093077) 1 NC_008767.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1093077 lipA 4676569 lipA Neisseria meningitidis FAM18 lipoyl synthase YP_975149.1 1092007 R 272831 CDS YP_975150.1 121634905 4676395 complement(1092983..1093555) 1 NC_008767.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1093555 lipB 4676395 lipB Neisseria meningitidis FAM18 lipoate-protein ligase B YP_975150.1 1092983 R 272831 CDS YP_975151.1 121634906 4676379 complement(1093608..1093883) 1 NC_008767.1 hypothetical protein 1093883 4676379 NMC1112 Neisseria meningitidis FAM18 hypothetical protein YP_975151.1 1093608 R 272831 CDS YP_975152.1 121634907 4675905 1094068..1095138 1 NC_008767.1 hypothetical protein 1095138 4675905 NMC1113 Neisseria meningitidis FAM18 hypothetical protein YP_975152.1 1094068 D 272831 CDS YP_975153.1 121634908 4675859 complement(1095385..1096332) 1 NC_008767.1 hypothetical protein 1096332 4675859 NMC1114 Neisseria meningitidis FAM18 hypothetical protein YP_975153.1 1095385 R 272831 CDS YP_975154.1 121634909 4675901 complement(1096347..1096766) 1 NC_008767.1 hypothetical protein 1096766 4675901 NMC1115 Neisseria meningitidis FAM18 hypothetical protein YP_975154.1 1096347 R 272831 CDS YP_975155.1 121634910 4675883 1096835..1097494 1 NC_008767.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1097494 4675883 NMC1116 Neisseria meningitidis FAM18 uracil-DNA glycosylase YP_975155.1 1096835 D 272831 CDS YP_975156.1 121634911 4676703 1097553..1098086 1 NC_008767.1 hypothetical protein 1098086 4676703 NMC1117 Neisseria meningitidis FAM18 hypothetical protein YP_975156.1 1097553 D 272831 CDS YP_975157.1 121634912 4675160 complement(1098201..1098650) 1 NC_008767.1 multiple antibiotic resistance; transcriptional regulator 1098650 4675160 NMC1118 Neisseria meningitidis FAM18 transcriptional regulator YP_975157.1 1098201 R 272831 CDS YP_975158.1 121634913 4676176 complement(1099113..1100069) 1 NC_008767.1 transposase 1100069 4676176 NMC1120 Neisseria meningitidis FAM18 transposase YP_975158.1 1099113 R 272831 CDS YP_975159.1 121634914 4676628 1100551..1100643 1 NC_008767.1 hypothetical protein 1100643 4676628 NMC1121 Neisseria meningitidis FAM18 hypothetical protein YP_975159.1 1100551 D 272831 CDS YP_975160.1 121634915 4676593 1100666..1100815 1 NC_008767.1 hypothetical protein 1100815 4676593 NMC1122 Neisseria meningitidis FAM18 hypothetical protein YP_975160.1 1100666 D 272831 CDS YP_975161.1 121634916 4676688 1100906..1101061 1 NC_008767.1 transposase (fragment) 1101061 4676688 NMC1123 Neisseria meningitidis FAM18 transposase (fragment) YP_975161.1 1100906 D 272831 CDS YP_975162.1 121634917 4676565 complement(1101279..1101602) 1 NC_008767.1 hypothetical protein 1101602 4676565 NMC1124 Neisseria meningitidis FAM18 hypothetical protein YP_975162.1 1101279 R 272831 CDS YP_975163.1 121634918 4676573 complement(1101647..1102162) 1 NC_008767.1 hypothetical protein 1102162 4676573 NMC1125 Neisseria meningitidis FAM18 hypothetical protein YP_975163.1 1101647 R 272831 CDS YP_975164.1 121634919 4676550 complement(1102628..1104550) 1 NC_008767.1 coiled coils, 90-110, 568-587, 596-626; ABC transporter ATP-binding protein 1104550 4676550 NMC1126 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975164.1 1102628 R 272831 CDS YP_975165.1 121634920 4676568 complement(1104627..1105058) 1 NC_008767.1 hypothetical protein 1105058 4676568 NMC1127 Neisseria meningitidis FAM18 hypothetical protein YP_975165.1 1104627 R 272831 CDS YP_975166.2 229270474 4676547 1105196..1106503 1 NC_008767.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1106503 hom 4676547 hom Neisseria meningitidis FAM18 homoserine dehydrogenase YP_975166.2 1105196 D 272831 CDS YP_975167.1 121634922 4676422 1106496..1106930 1 NC_008767.1 hypothetical protein 1106930 4676422 NMC1129 Neisseria meningitidis FAM18 hypothetical protein YP_975167.1 1106496 D 272831 CDS YP_975168.1 121634923 4675855 complement(1106989..1107258) 1 NC_008767.1 DNA-binding protein 1107258 hupB 4675855 hupB Neisseria meningitidis FAM18 DNA-binding protein YP_975168.1 1106989 R 272831 CDS YP_975169.1 121634924 4676455 complement(1107440..1109890) 1 NC_008767.1 ATP-dependent protease 1109890 lon 4676455 lon Neisseria meningitidis FAM18 ATP-dependent protease YP_975169.1 1107440 R 272831 CDS YP_975170.1 121634925 4676391 1110249..1111244 1 NC_008767.1 hypothetical protein 1111244 4676391 NMC1132 Neisseria meningitidis FAM18 hypothetical protein YP_975170.1 1110249 D 272831 CDS YP_975171.1 121634926 4676506 complement(1111272..1113017) 1 NC_008767.1 exodeoxyribonuclease V subunit alpha 1113017 recD 4676506 recD Neisseria meningitidis FAM18 exodeoxyribonuclease V subunit alpha YP_975171.1 1111272 R 272831 CDS YP_975172.1 121634927 4675757 complement(1113085..1113771) 1 NC_008767.1 ABC transporter ATP-binding protein 1113771 4675757 NMC1134 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975172.1 1113085 R 272831 CDS YP_975173.1 121634928 4676272 complement(1113773..1115020) 1 NC_008767.1 hypothetical protein 1115020 4676272 NMC1135 Neisseria meningitidis FAM18 hypothetical protein YP_975173.1 1113773 R 272831 CDS YP_975174.1 121634929 4676496 1115213..1115503 1 NC_008767.1 hypothetical protein 1115503 4676496 NMC1136 Neisseria meningitidis FAM18 hypothetical protein YP_975174.1 1115213 D 272831 CDS YP_975175.1 121634930 4676458 complement(1115559..1116179) 1 NC_008767.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1116179 recR 4676458 recR Neisseria meningitidis FAM18 recombination protein RecR YP_975175.1 1115559 R 272831 CDS YP_975176.1 121634931 4675671 complement(1116243..1117781) 1 NC_008767.1 peptidyl-prolyl cis-trans isomerase 1117781 4675671 NMC1138 Neisseria meningitidis FAM18 peptidyl-prolyl cis-trans isomerase YP_975176.1 1116243 R 272831 CDS YP_975177.1 121634932 4676462 complement(1117836..1118210) 1 NC_008767.1 hypothetical protein 1118210 4676462 NMC1139 Neisseria meningitidis FAM18 hypothetical protein YP_975177.1 1117836 R 272831 CDS YP_975178.1 121634933 4676459 1118360..1119988 1 NC_008767.1 ABC transporter ATP-binding protein 1119988 4676459 NMC1140 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975178.1 1118360 D 272831 CDS YP_975179.1 121634934 4676393 1120060..1121313 1 NC_008767.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 1121313 cca 4676393 cca Neisseria meningitidis FAM18 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_975179.1 1120060 D 272831 CDS YP_975180.1 121634935 4676542 1121536..1121844 1 NC_008767.1 hypothetical protein 1121844 4676542 NMC1143 Neisseria meningitidis FAM18 hypothetical protein YP_975180.1 1121536 D 272831 CDS YP_975181.1 121634936 4676412 1121926..1122957 1 NC_008767.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1122957 ruvB 4676412 ruvB Neisseria meningitidis FAM18 Holliday junction DNA helicase RuvB YP_975181.1 1121926 D 272831 CDS YP_975182.1 121634937 4675530 complement(1122980..1123708) 1 NC_008767.1 ribulose-phosphate 3-epimerase 1123708 rpe 4675530 rpe Neisseria meningitidis FAM18 ribulose-phosphate 3-epimerase YP_975182.1 1122980 R 272831 CDS YP_975183.1 121634938 4675411 1123854..1124288 1 NC_008767.1 hypothetical protein 1124288 4675411 NMC1146 Neisseria meningitidis FAM18 hypothetical protein YP_975183.1 1123854 D 272831 CDS YP_975184.1 121634939 4676373 complement(join(1124301..1124507,1124511..1125164)) 1 NC_008767.1 hypothetical protein 1125164 4676373 NMC1147 Neisseria meningitidis FAM18 hypothetical protein YP_975184.1 1124301 R 272831 CDS YP_975185.2 161723298 4676365 complement(1125172..1125789) 1 NC_008767.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1125789 ribC 4676365 ribC Neisseria meningitidis FAM18 riboflavin synthase subunit alpha YP_975185.2 1125172 R 272831 CDS YP_975186.1 121634941 4675598 complement(1125952..1126530) 1 NC_008767.1 molybdopterin-guanine dinucleotide biosynthesis protein A 1126530 4675598 NMC1149 Neisseria meningitidis FAM18 molybdopterin-guanine dinucleotide biosynthesis protein A YP_975186.1 1125952 R 272831 CDS YP_975187.1 121634942 4676169 1126772..1128544 1 NC_008767.1 two-component system sensor kinase 1128544 4676169 NMC1150 Neisseria meningitidis FAM18 two-component system sensor kinase YP_975187.1 1126772 D 272831 CDS YP_975188.1 121634943 4676317 1128541..1129197 1 NC_008767.1 two-component system response regulator 1129197 4676317 NMC1151 Neisseria meningitidis FAM18 two-component system response regulator YP_975188.1 1128541 D 272831 CDS YP_975189.1 121634944 4676292 complement(1129671..1130705) 1 NC_008767.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1130705 purM 4676292 purM Neisseria meningitidis FAM18 phosphoribosylaminoimidazole synthetase YP_975189.1 1129671 R 272831 CDS YP_975190.1 121634945 4675795 1131464..1132141 1 NC_008767.1 hypothetical protein 1132141 4675795 NMC1154 Neisseria meningitidis FAM18 hypothetical protein YP_975190.1 1131464 D 272831 CDS YP_975191.1 121634946 4676360 1132134..1132727 1 NC_008767.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1132727 ribA 4676360 ribA Neisseria meningitidis FAM18 GTP cyclohydrolase II YP_975191.1 1132134 D 272831 CDS YP_975192.1 121634947 4675602 join(1132895..1133209,1133208..1133909) 1 NC_008767.1 hypothetical protein 1133909 4675602 NMC1156 Neisseria meningitidis FAM18 hypothetical protein YP_975192.1 1132895 D 272831 CDS YP_975193.2 229270473 4676188 1134377..1135468 1 NC_008767.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein 1135468 ribB 4676188 ribB Neisseria meningitidis FAM18 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein YP_975193.2 1134377 D 272831 CDS YP_975194.1 121634949 4675597 complement(1135776..1136102) 1 NC_008767.1 type I restriction enzyme system modification protein 1136102 4675597 NMC1158 Neisseria meningitidis FAM18 type I restriction enzyme system modification protein YP_975194.1 1135776 R 272831 CDS YP_975195.1 121634950 4676330 complement(1136390..1137700) 1 NC_008767.1 recombination factor protein RarA 1137700 4676330 NMC1159 Neisseria meningitidis FAM18 recombination factor protein RarA YP_975195.1 1136390 R 272831 CDS YP_975196.1 121634951 4676243 1137949..1138434 1 NC_008767.1 hypothetical protein 1138434 4676243 NMC1160 Neisseria meningitidis FAM18 hypothetical protein YP_975196.1 1137949 D 272831 CDS YP_975197.1 121634952 4676247 complement(1139484..1140437) 1 NC_008767.1 LysR family transcriptional regulator 1140437 4676247 NMC1162 Neisseria meningitidis FAM18 LysR family transcriptional regulator YP_975197.1 1139484 R 272831 CDS YP_975198.1 121634953 4676203 1140612..1142123 1 NC_008767.1 hypothetical protein 1142123 4676203 NMC1163 Neisseria meningitidis FAM18 hypothetical protein YP_975198.1 1140612 D 272831 CDS YP_975199.1 121634954 4676196 1142375..1142746 1 NC_008767.1 lipoprotein 1142746 4676196 NMC1164 Neisseria meningitidis FAM18 lipoprotein YP_975199.1 1142375 D 272831 CDS YP_975200.1 121634955 4676213 1142819..1144228 1 NC_008767.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1144228 thrC 4676213 thrC Neisseria meningitidis FAM18 threonine synthase YP_975200.1 1142819 D 272831 CDS YP_975201.1 121634956 4675198 1144274..1145068 1 NC_008767.1 hypothetical protein 1145068 4675198 NMC1166 Neisseria meningitidis FAM18 hypothetical protein YP_975201.1 1144274 D 272831 CDS YP_975202.1 121634957 4676193 1145256..1146032 1 NC_008767.1 ferredoxin-NADP reductase 1146032 fpr 4676193 fpr Neisseria meningitidis FAM18 ferredoxin-NADP reductase YP_975202.1 1145256 D 272831 CDS YP_975203.1 121634958 4676684 complement(1146700..1149210) 1 NC_008767.1 P-type cation-transporting ATPase 1149210 4676684 NMC1170 Neisseria meningitidis FAM18 P-type cation-transporting ATPase YP_975203.1 1146700 R 272831 CDS YP_975204.1 121634959 4676190 complement(1149168..1150346) 1 NC_008767.1 hypothetical protein 1150346 4676190 NMC1171 Neisseria meningitidis FAM18 hypothetical protein YP_975204.1 1149168 R 272831 CDS YP_975205.1 121634960 4676234 complement(1150351..1151655) 1 NC_008767.1 hypothetical protein 1151655 4676234 NMC1172 Neisseria meningitidis FAM18 hypothetical protein YP_975205.1 1150351 R 272831 CDS YP_975206.1 121634961 4676181 complement(1151784..1152509) 1 NC_008767.1 hypothetical protein 1152509 4676181 NMC1173 Neisseria meningitidis FAM18 hypothetical protein YP_975206.1 1151784 R 272831 CDS YP_975207.1 121634962 4676164 complement(1152582..1153259) 1 NC_008767.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1153259 radC 4676164 radC Neisseria meningitidis FAM18 DNA repair protein RadC YP_975207.1 1152582 R 272831 CDS YP_975208.1 121634963 4675734 complement(1153382..1154731) 1 NC_008767.1 glutamate--cysteine ligase 1154731 gshA 4675734 gshA Neisseria meningitidis FAM18 glutamate--cysteine ligase YP_975208.1 1153382 R 272831 CDS YP_975209.1 121634964 4676529 1154991..1156400 1 NC_008767.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1156400 leuC 4676529 leuC Neisseria meningitidis FAM18 isopropylmalate isomerase large subunit YP_975209.1 1154991 D 272831 CDS YP_975210.1 121634965 4676388 1156446..1156751 1 NC_008767.1 lipoprotein 1156751 4676388 NMC1178 Neisseria meningitidis FAM18 lipoprotein YP_975210.1 1156446 D 272831 CDS YP_975211.1 121634966 4676137 1156813..1157454 1 NC_008767.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1157454 leuD 4676137 leuD Neisseria meningitidis FAM18 isopropylmalate isomerase small subunit YP_975211.1 1156813 D 272831 CDS YP_975212.1 121634967 4676229 join(1157624..1158025,1158025..1158420,1158420..1158893) 1 NC_008767.1 deleted EC_number 2.1.1.73; DNA modification methylase 1158893 4676229 NMC1180 Neisseria meningitidis FAM18 DNA modification methylase YP_975212.1 1157624 D 272831 CDS YP_975213.1 121634968 4676141 join(1158909..1159067,1159071..1159640) 1 NC_008767.1 type II restriction endonuclease 1159640 4676141 NMC1181 Neisseria meningitidis FAM18 type II restriction endonuclease YP_975213.1 1158909 D 272831 CDS YP_975214.1 121634969 4676144 1159674..1160744 1 NC_008767.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1160744 leuB 4676144 leuB Neisseria meningitidis FAM18 3-isopropylmalate dehydrogenase YP_975214.1 1159674 D 272831 CDS YP_975215.1 121634970 4676387 1160907..1161470 1 NC_008767.1 hypothetical protein 1161470 4676387 NMC1183 Neisseria meningitidis FAM18 hypothetical protein YP_975215.1 1160907 D 272831 CDS YP_975216.1 121634971 4676138 1161930..1163327 1 NC_008767.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1163327 aspA 4676138 aspA Neisseria meningitidis FAM18 aspartate ammonia-lyase YP_975216.1 1161930 D 272831 CDS YP_975217.1 121634972 4675620 complement(1163399..1164274) 1 NC_008767.1 hypothetical protein 1164274 4675620 NMC1186 Neisseria meningitidis FAM18 hypothetical protein YP_975217.1 1163399 R 272831 CDS YP_975218.1 121634973 4676100 complement(1164276..1164998) 1 NC_008767.1 molecuar chaperone DnaJ 1164998 4676100 NMC1188 Neisseria meningitidis FAM18 molecuar chaperone DnaJ YP_975218.1 1164276 R 272831 CDS YP_975219.1 121634974 4676133 complement(1165020..1165499) 1 NC_008767.1 hypothetical protein 1165499 4676133 NMC1189 Neisseria meningitidis FAM18 hypothetical protein YP_975219.1 1165020 R 272831 CDS YP_975220.1 121634975 4675977 1165560..1165937 1 NC_008767.1 hypothetical protein 1165937 4675977 NMC1190 Neisseria meningitidis FAM18 hypothetical protein YP_975220.1 1165560 D 272831 CDS YP_975221.1 121634976 4676051 1165969..1166835 1 NC_008767.1 hypothetical protein 1166835 4676051 NMC1191 Neisseria meningitidis FAM18 hypothetical protein YP_975221.1 1165969 D 272831 CDS YP_975222.1 121634977 4676039 1166933..1167892 1 NC_008767.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1167892 4676039 NMC1192 Neisseria meningitidis FAM18 C32 tRNA thiolase YP_975222.1 1166933 D 272831 CDS YP_975223.1 121634978 4676035 complement(1167986..1170925) 1 NC_008767.1 type III restriction-modification system endonuclease protein 1170925 4676035 NMC1193 Neisseria meningitidis FAM18 type III restriction-modification system endonuclease protein YP_975223.1 1167986 R 272831 CDS YP_975224.1 121634979 4675680 complement(join(1170938..1172824,1172823..1172912)) 1 NC_008767.1 hypothetical protein 1172912 4675680 NMC1194 Neisseria meningitidis FAM18 hypothetical protein YP_975224.1 1170938 R 272831 CDS YP_975225.1 121634980 4675699 complement(1173028..1173585) 1 NC_008767.1 peptidyl-prolyl cis-trans isomerase A 1173585 ppiA 4675699 ppiA Neisseria meningitidis FAM18 peptidyl-prolyl cis-trans isomerase A YP_975225.1 1173028 R 272831 CDS YP_975226.1 121634981 4676074 complement(1173650..1174576) 1 NC_008767.1 hypothetical protein 1174576 4676074 NMC1196 Neisseria meningitidis FAM18 hypothetical protein YP_975226.1 1173650 R 272831 CDS YP_975227.1 121634982 4675675 complement(1174564..1175157) 1 NC_008767.1 cation uptake regulator 1175157 4675675 NMC1197 Neisseria meningitidis FAM18 cation uptake regulator YP_975227.1 1174564 R 272831 CDS YP_975228.1 121634983 4675690 complement(1175111..1175668) 1 NC_008767.1 protein-tyrosine-phosphatase 1175668 4675690 NMC1198 Neisseria meningitidis FAM18 protein-tyrosine-phosphatase YP_975228.1 1175111 R 272831 CDS YP_975229.1 121634984 4675661 complement(1175691..1176806) 1 NC_008767.1 hypothetical protein 1176806 4675661 NMC1199 Neisseria meningitidis FAM18 hypothetical protein YP_975229.1 1175691 R 272831 CDS YP_975230.1 121634985 4675660 complement(1176920..1178017) 1 NC_008767.1 hypothetical protein 1178017 4675660 NMC1200 Neisseria meningitidis FAM18 hypothetical protein YP_975230.1 1176920 R 272831 CDS YP_975231.1 121634986 4675563 complement(1178099..1179730) 1 NC_008767.1 hypothetical protein 1179730 4675563 NMC1201 Neisseria meningitidis FAM18 hypothetical protein YP_975231.1 1178099 R 272831 CDS YP_975232.1 121634987 4675558 complement(1179830..1180042) 1 NC_008767.1 mercuric ion binding protein 1180042 4675558 NMC1202 Neisseria meningitidis FAM18 mercuric ion binding protein YP_975232.1 1179830 R 272831 CDS YP_975233.1 121634988 4675555 1180672..1182108 1 NC_008767.1 polysaccharide modification protein 1182108 4675555 NMC1203 Neisseria meningitidis FAM18 polysaccharide modification protein YP_975233.1 1180672 D 272831 CDS YP_975234.1 121634989 4675554 1182119..1183105 1 NC_008767.1 hypothetical protein 1183105 4675554 NMC1204 Neisseria meningitidis FAM18 hypothetical protein YP_975234.1 1182119 D 272831 CDS YP_975235.1 121634990 4675549 1183102..1184295 1 NC_008767.1 hypothetical protein 1184295 4675549 NMC1205 Neisseria meningitidis FAM18 hypothetical protein YP_975235.1 1183102 D 272831 CDS YP_975236.1 121634991 4675425 1184505..1186097 1 NC_008767.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1186097 4675425 NMC1207 Neisseria meningitidis FAM18 long-chain-fatty-acid--CoA ligase YP_975236.1 1184505 D 272831 CDS YP_975237.1 121634992 4675423 complement(1186187..1188214) 1 NC_008767.1 transmembrane transport protein 1188214 4675423 NMC1208 Neisseria meningitidis FAM18 transmembrane transport protein YP_975237.1 1186187 R 272831 CDS YP_975238.1 121634993 4675415 1188503..1190509 1 NC_008767.1 site-specific recombinase 1190509 gcr 4675415 gcr Neisseria meningitidis FAM18 site-specific recombinase YP_975238.1 1188503 D 272831 CDS YP_975239.1 121634994 4676597 complement(1190632..1191723) 1 NC_008767.1 murein hydrolase 1191723 mltB 4676597 mltB Neisseria meningitidis FAM18 murein hydrolase YP_975239.1 1190632 R 272831 CDS YP_975240.1 121634995 4676289 complement(1191872..1193425) 1 NC_008767.1 oxidoreductase 1193425 4676289 NMC1213 Neisseria meningitidis FAM18 oxidoreductase YP_975240.1 1191872 R 272831 CDS YP_975241.1 121634996 4675414 1193484..1197611 1 NC_008767.1 transcription-repair coupling factor 1197611 mfd 4675414 mfd Neisseria meningitidis FAM18 transcription-repair coupling factor YP_975241.1 1193484 D 272831 CDS YP_975242.1 121634997 4676274 1197760..1198143 1 NC_008767.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 1198143 panD 4676274 panD Neisseria meningitidis FAM18 aspartate alpha-decarboxylase YP_975242.1 1197760 D 272831 CDS YP_975243.1 121634998 4676179 1198165..1199007 1 NC_008767.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1199007 kdsA 4676179 kdsA Neisseria meningitidis FAM18 2-dehydro-3-deoxyphosphooctonate aldolase YP_975243.1 1198165 D 272831 CDS YP_975244.1 121634999 4675904 1199022..1199462 1 NC_008767.1 hypothetical protein 1199462 4675904 NMC1219 Neisseria meningitidis FAM18 hypothetical protein YP_975244.1 1199022 D 272831 CDS YP_975245.1 121635000 4675401 1199509..1200795 1 NC_008767.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1200795 eno 4675401 eno Neisseria meningitidis FAM18 phosphopyruvate hydratase YP_975245.1 1199509 D 272831 CDS YP_975246.1 121635001 4675900 1200809..1201087 1 NC_008767.1 hypothetical protein 1201087 4675900 NMC1221 Neisseria meningitidis FAM18 hypothetical protein YP_975246.1 1200809 D 272831 CDS YP_975247.1 121635002 4675396 complement(1201128..1201418) 1 NC_008767.1 iron-sulfur binding protein 1201418 4675396 NMC1222 Neisseria meningitidis FAM18 iron-sulfur binding protein YP_975247.1 1201128 R 272831 CDS YP_975248.1 121635003 4675395 complement(1201643..1202776) 1 NC_008767.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1202776 nrdB 4675395 nrdB Neisseria meningitidis FAM18 ribonucleotide-diphosphate reductase subunit beta YP_975248.1 1201643 R 272831 CDS YP_975249.1 121635004 4676220 complement(1202990..1203913) 1 NC_008767.1 hypothetical protein 1203913 4676220 NMC1225 Neisseria meningitidis FAM18 hypothetical protein YP_975249.1 1202990 R 272831 CDS YP_975250.1 121635005 4675391 complement(1203936..1206215) 1 NC_008767.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1206215 nrdA 4675391 nrdA Neisseria meningitidis FAM18 ribonucleotide-diphosphate reductase subunit alpha YP_975250.1 1203936 R 272831 CDS YP_975251.1 121635006 4676125 1206744..1207055 1 NC_008767.1 secreted protein; hypothetical protein 1207055 4676125 NMC1229 Neisseria meningitidis FAM18 hypothetical protein YP_975251.1 1206744 D 272831 CDS YP_975252.1 121635007 4675390 complement(1207366..1208133) 1 NC_008767.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 1208133 4675390 NMC1231 Neisseria meningitidis FAM18 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_975252.1 1207366 R 272831 CDS YP_975253.1 121635008 4675389 complement(1208221..1209063) 1 NC_008767.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1209063 fpg 4675389 fpg Neisseria meningitidis FAM18 formamidopyrimidine-DNA glycosylase YP_975253.1 1208221 R 272831 CDS YP_975254.1 121635009 4676687 complement(1209100..1209765) 1 NC_008767.1 hypothetical protein 1209765 4676687 NMC1233 Neisseria meningitidis FAM18 hypothetical protein YP_975254.1 1209100 R 272831 CDS YP_975255.1 121635010 4675386 1209944..1211920 1 NC_008767.1 membrane bound murein transglycosylase 1211920 4675386 NMC1234 Neisseria meningitidis FAM18 membrane bound murein transglycosylase YP_975255.1 1209944 D 272831 CDS YP_975256.1 121635011 4675378 1211988..1212680 1 NC_008767.1 ribosomal small subunit pseudouridine synthase 1212680 4675378 NMC1235 Neisseria meningitidis FAM18 ribosomal small subunit pseudouridine synthase YP_975256.1 1211988 D 272831 CDS YP_975257.1 121635012 4675374 1214782..1215438 1 NC_008767.1 cytidylate kinase 1215438 cmk 4675374 cmk Neisseria meningitidis FAM18 cytidylate kinase YP_975257.1 1214782 D 272831 CDS YP_975258.1 121635013 4676672 1215567..1217279 1 NC_008767.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1217279 rpsA 4676672 rpsA Neisseria meningitidis FAM18 30S ribosomal protein S1 YP_975258.1 1215567 D 272831 CDS YP_975259.1 121635014 4675266 1217290..1217604 1 NC_008767.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1217604 ihfB 4675266 ihfB Neisseria meningitidis FAM18 integration host factor subunit beta YP_975259.1 1217290 D 272831 CDS YP_975260.1 121635015 4676468 complement(1217954..1218361) 1 NC_008767.1 transcriptional regulator 1218361 4676468 NMC1240 Neisseria meningitidis FAM18 transcriptional regulator YP_975260.1 1217954 R 272831 CDS YP_975261.1 121635016 4675371 1218482..1219618 1 NC_008767.1 deleted EC_number 1.2.1.1; alcohol dehydrogenase 1219618 adhC 4675371 adhC Neisseria meningitidis FAM18 alcohol dehydrogenase YP_975261.1 1218482 D 272831 CDS YP_975262.1 121635017 4675504 1219627..1220454 1 NC_008767.1 esterase 1220454 esd 4675504 esd Neisseria meningitidis FAM18 esterase YP_975262.1 1219627 D 272831 CDS YP_975263.1 121635018 4675889 1220845..1221996 1 NC_008767.1 nucleotide-binding protein 1221996 4675889 NMC1243 Neisseria meningitidis FAM18 nucleotide-binding protein YP_975263.1 1220845 D 272831 CDS YP_975264.1 121635019 4675364 1222055..1222480 1 NC_008767.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1222480 ndk 4675364 ndk Neisseria meningitidis FAM18 nucleoside diphosphate kinase YP_975264.1 1222055 D 272831 CDS YP_975265.1 121635020 4676238 1222623..1223717 1 NC_008767.1 hypothetical protein 1223717 4676238 NMC1245 Neisseria meningitidis FAM18 hypothetical protein YP_975265.1 1222623 D 272831 CDS YP_975266.1 121635021 4675363 1223684..1224481 1 NC_008767.1 lipoprotein 1224481 4675363 NMC1246 Neisseria meningitidis FAM18 lipoprotein YP_975266.1 1223684 D 272831 CDS YP_975267.1 121635022 4675361 1224497..1225762 1 NC_008767.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1225762 ispG 4675361 ispG Neisseria meningitidis FAM18 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_975267.1 1224497 D 272831 CDS YP_975268.1 121635023 4675290 complement(1225819..1226433) 1 NC_008767.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1226433 clpP 4675290 clpP Neisseria meningitidis FAM18 ATP-dependent Clp protease proteolytic subunit YP_975268.1 1225819 R 272831 CDS YP_975269.1 121635024 4676503 complement(1226529..1227842) 1 NC_008767.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1227842 tig 4676503 tig Neisseria meningitidis FAM18 trigger factor YP_975269.1 1226529 R 272831 CDS YP_975270.1 121635025 4675193 complement(1228048..1230486) 1 NC_008767.1 DNA translocase FtsK 1230486 4675193 NMC1251 Neisseria meningitidis FAM18 DNA translocase FtsK YP_975270.1 1228048 R 272831 CDS YP_975271.1 121635026 4675286 1230685..1231920 1 NC_008767.1 uracil permease 1231920 uraA 4675286 uraA Neisseria meningitidis FAM18 uracil permease YP_975271.1 1230685 D 272831 CDS YP_975272.1 121635027 4676671 complement(1231972..1232454) 1 NC_008767.1 hypothetical protein 1232454 4676671 NMC1253 Neisseria meningitidis FAM18 hypothetical protein YP_975272.1 1231972 R 272831 CDS YP_975273.1 121635028 4675284 join(1232560..1232751,1232751..1232963) 1 NC_008767.1 hypothetical protein 1232963 4675284 NMC1254 Neisseria meningitidis FAM18 hypothetical protein YP_975273.1 1232560 D 272831 CDS YP_975274.1 121635029 4675280 1233037..1233783 1 NC_008767.1 phosphatidylserine synthase 1233783 pss 4675280 pss Neisseria meningitidis FAM18 phosphatidylserine synthase YP_975274.1 1233037 D 272831 CDS YP_975275.1 121635030 4675984 1233784..1234590 1 NC_008767.1 hypothetical protein 1234590 4675984 NMC1256 Neisseria meningitidis FAM18 hypothetical protein YP_975275.1 1233784 D 272831 CDS YP_975276.1 121635031 4675824 complement(1235378..1235830) 1 NC_008767.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1235830 rplI 4675824 rplI Neisseria meningitidis FAM18 50S ribosomal protein L9 YP_975276.1 1235378 R 272831 CDS YP_975277.1 121635032 4675463 complement(1235847..1236077) 1 NC_008767.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1236077 rpsR 4675463 rpsR Neisseria meningitidis FAM18 30S ribosomal protein S18 YP_975277.1 1235847 R 272831 CDS YP_975278.1 121635033 4675219 complement(1236084..1236386) 1 NC_008767.1 primosomal replication protein 1236386 priB 4675219 priB Neisseria meningitidis FAM18 primosomal replication protein YP_975278.1 1236084 R 272831 CDS YP_975279.1 121635034 4676068 complement(1236387..1236755) 1 NC_008767.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1236755 rpsF 4676068 rpsF Neisseria meningitidis FAM18 30S ribosomal protein S6 YP_975279.1 1236387 R 272831 CDS YP_975280.1 121635035 4675304 complement(1236910..1237860) 1 NC_008767.1 thioredoxin reductase 1237860 trxB 4675304 trxB Neisseria meningitidis FAM18 thioredoxin reductase YP_975280.1 1236910 R 272831 CDS YP_975281.1 121635036 4675184 1237849..1240161 1 NC_008767.1 cation-transporting ATPase 1240161 4675184 NMC1262 Neisseria meningitidis FAM18 cation-transporting ATPase YP_975281.1 1237849 D 272831 CDS YP_975282.1 121635037 4675132 1240216..1242102 1 NC_008767.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1242102 uvrC 4675132 uvrC Neisseria meningitidis FAM18 excinuclease ABC subunit C YP_975282.1 1240216 D 272831 CDS YP_975283.1 121635038 4676601 join(1242189..1242491,1242490..1243623) 1 NC_008767.1 hypothetical protein 1243623 4676601 NMC1265 Neisseria meningitidis FAM18 hypothetical protein YP_975283.1 1242189 D 272831 CDS YP_975284.1 121635039 4675127 1243745..1244461 1 NC_008767.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1244461 trmB 4675127 trmB Neisseria meningitidis FAM18 tRNA (guanine-N(7)-)-methyltransferase YP_975284.1 1243745 D 272831 CDS YP_975285.1 121635040 4675115 complement(1244642..1244929) 1 NC_008767.1 hypothetical protein 1244929 4675115 NMC1268 Neisseria meningitidis FAM18 hypothetical protein YP_975285.1 1244642 R 272831 CDS YP_975286.1 121635041 4675489 complement(1245041..1247068) 1 NC_008767.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1247068 uvrB 4675489 uvrB Neisseria meningitidis FAM18 excinuclease ABC subunit B YP_975286.1 1245041 R 272831 CDS YP_975287.1 121635042 4676417 complement(1247397..1248881) 1 NC_008767.1 carboxy-terminal processing protease 1248881 4676417 NMC1270 Neisseria meningitidis FAM18 carboxy-terminal processing protease YP_975287.1 1247397 R 272831 CDS YP_975288.1 121635043 4675080 complement(1249008..1250813) 1 NC_008767.1 hypothetical protein 1250813 4675080 NMC1271 Neisseria meningitidis FAM18 hypothetical protein YP_975288.1 1249008 R 272831 CDS YP_975289.1 121635044 4675078 1251141..1251701 1 NC_008767.1 lipoprotein 1251701 4675078 NMC1273 Neisseria meningitidis FAM18 lipoprotein YP_975289.1 1251141 D 272831 CDS YP_975290.1 121635045 4675076 1251703..1252251 1 NC_008767.1 hypothetical protein 1252251 4675076 NMC1274 Neisseria meningitidis FAM18 hypothetical protein YP_975290.1 1251703 D 272831 CDS YP_975291.1 121635046 4675023 1252244..1252699 1 NC_008767.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1252699 4675023 NMC1275 Neisseria meningitidis FAM18 Holliday junction resolvase-like protein YP_975291.1 1252244 D 272831 CDS YP_975292.1 121635047 4674938 complement(1252709..1253365) 1 NC_008767.1 hydrolase 1253365 4674938 NMC1276 Neisseria meningitidis FAM18 hydrolase YP_975292.1 1252709 R 272831 CDS YP_975293.1 121635048 4674927 complement(1253428..1255140) 1 NC_008767.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1255140 proS 4674927 proS Neisseria meningitidis FAM18 prolyl-tRNA synthetase YP_975293.1 1253428 R 272831 CDS YP_975294.1 121635049 4676052 1255834..1258497 1 NC_008767.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1258497 aceE 4676052 aceE Neisseria meningitidis FAM18 pyruvate dehydrogenase subunit E1 YP_975294.1 1255834 D 272831 CDS YP_975295.1 121635050 4675427 1258647..1260248 1 NC_008767.1 dihydrolipoamide acetyltransferase 1260248 aceF 4675427 aceF Neisseria meningitidis FAM18 dihydrolipoamide acetyltransferase YP_975295.1 1258647 D 272831 CDS YP_975296.1 121635051 4676165 1260325..1262112 1 NC_008767.1 dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) 1262112 lpdA 4676165 lpdA Neisseria meningitidis FAM18 dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) YP_975296.1 1260325 D 272831 CDS YP_975297.1 121635052 4676356 complement(1262472..1264010) 1 NC_008767.1 hypothetical protein 1264010 4676356 NMC1281 Neisseria meningitidis FAM18 hypothetical protein YP_975297.1 1262472 R 272831 CDS YP_975298.1 121635053 4674899 complement(1264146..1266269) 1 NC_008767.1 TonB-dependent receptor protein 1266269 4674899 NMC1282 Neisseria meningitidis FAM18 TonB-dependent receptor protein YP_975298.1 1264146 R 272831 CDS YP_975299.1 121635054 4674867 complement(1266539..1267324) 1 NC_008767.1 inositol monophosphatase 1267324 4674867 NMC1283 Neisseria meningitidis FAM18 inositol monophosphatase YP_975299.1 1266539 R 272831 CDS YP_975300.1 121635055 4674847 1267505..1268383 1 NC_008767.1 SpoU methylase family protein 1268383 4674847 NMC1284 Neisseria meningitidis FAM18 SpoU methylase family protein YP_975300.1 1267505 D 272831 CDS YP_975301.1 121635056 4674843 1268423..1269301 1 NC_008767.1 hypothetical protein 1269301 4674843 NMC1285 Neisseria meningitidis FAM18 hypothetical protein YP_975301.1 1268423 D 272831 CDS YP_975302.1 121635057 4674839 1269337..1270593 1 NC_008767.1 SUN-family protein 1270593 4674839 NMC1286 Neisseria meningitidis FAM18 SUN-family protein YP_975302.1 1269337 D 272831 CDS YP_975303.1 121635058 4674834 1271689..1272123 1 NC_008767.1 coiled coil, 93-110; hypothetical protein 1272123 4674834 NMC1287 Neisseria meningitidis FAM18 hypothetical protein YP_975303.1 1271689 D 272831 CDS YP_975304.1 121635059 4674829 complement(1272172..1273515) 1 NC_008767.1 aldehyde dehydrogenase 1273515 4674829 NMC1288 Neisseria meningitidis FAM18 aldehyde dehydrogenase YP_975304.1 1272172 R 272831 CDS YP_975305.1 121635060 4674792 complement(1273520..1274233) 1 NC_008767.1 hypothetical protein 1274233 4674792 NMC1289 Neisseria meningitidis FAM18 hypothetical protein YP_975305.1 1273520 R 272831 CDS YP_975306.1 121635061 4674787 1274315..1274614 1 NC_008767.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1274614 gatC 4674787 gatC Neisseria meningitidis FAM18 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_975306.1 1274315 D 272831 CDS YP_975307.1 121635062 4676620 1274677..1276122 1 NC_008767.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1276122 gatA 4676620 gatA Neisseria meningitidis FAM18 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_975307.1 1274677 D 272831 CDS YP_975308.1 121635063 4676638 1276119..1277051 1 NC_008767.1 hypothetical protein 1277051 4676638 NMC1292 Neisseria meningitidis FAM18 hypothetical protein YP_975308.1 1276119 D 272831 CDS YP_975309.1 121635064 4674786 1277094..1278524 1 NC_008767.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1278524 gatB 4674786 gatB Neisseria meningitidis FAM18 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_975309.1 1277094 D 272831 CDS YP_975310.1 121635065 4676619 1278616..1279626 1 NC_008767.1 iron/sulfur-binding oxidoreductase 1279626 4676619 NMC1294 Neisseria meningitidis FAM18 iron/sulfur-binding oxidoreductase YP_975310.1 1278616 D 272831 CDS YP_975311.1 121635066 4674772 complement(1279755..1280387) 1 NC_008767.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1280387 pdxH 4674772 pdxH Neisseria meningitidis FAM18 pyridoxamine 5'-phosphate oxidase YP_975311.1 1279755 R 272831 CDS YP_975312.1 121635067 4676156 1281044..1281814 1 NC_008767.1 pseudouridine synthase 1281814 4676156 NMC1296 Neisseria meningitidis FAM18 pseudouridine synthase YP_975312.1 1281044 D 272831 CDS YP_975313.1 121635068 4674766 complement(1281883..1283424) 1 NC_008767.1 integral membrane transporter 1283424 4674766 NMC1297 Neisseria meningitidis FAM18 integral membrane transporter YP_975313.1 1281883 R 272831 CDS YP_975314.1 121635069 4674752 complement(1284671..1286026) 1 NC_008767.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1286026 xseA 4674752 xseA Neisseria meningitidis FAM18 exodeoxyribonuclease VII large subunit YP_975314.1 1284671 R 272831 CDS YP_975315.1 121635070 4676682 1286223..1287044 1 NC_008767.1 NH(3)-dependent NAD synthetase 1287044 nadE 4676682 nadE Neisseria meningitidis FAM18 NH(3)-dependent NAD synthetase YP_975315.1 1286223 D 272831 CDS YP_975316.1 121635071 4676253 complement(1287112..1287585) 1 NC_008767.1 hypothetical protein 1287585 4676253 NMC1300 Neisseria meningitidis FAM18 hypothetical protein YP_975316.1 1287112 R 272831 CDS YP_975317.1 121635072 4674748 1287883..1288215 1 NC_008767.1 thioredoxin 1288215 trxA 4674748 trxA Neisseria meningitidis FAM18 thioredoxin YP_975317.1 1287883 D 272831 CDS YP_975318.1 121635073 4675183 complement(1288268..1289185) 1 NC_008767.1 hypothetical protein 1289185 4675183 NMC1302 Neisseria meningitidis FAM18 hypothetical protein YP_975318.1 1288268 R 272831 CDS YP_975319.1 121635074 4676600 1289543..1290931 1 NC_008767.1 ATP-dependent RNA helicase 1290931 4676600 NMC1303 Neisseria meningitidis FAM18 ATP-dependent RNA helicase YP_975319.1 1289543 D 272831 CDS YP_975320.1 121635075 4676370 complement(1291573..1292127) 1 NC_008767.1 membrane lipoprotein 1292127 4676370 NMC1304 Neisseria meningitidis FAM18 membrane lipoprotein YP_975320.1 1291573 R 272831 CDS YP_975321.1 121635076 4676556 complement(1292212..1292772) 1 NC_008767.1 hypothetical protein 1292772 4676556 NMC1305 Neisseria meningitidis FAM18 hypothetical protein YP_975321.1 1292212 R 272831 CDS YP_975322.1 121635077 4676714 1293116..1294312 1 NC_008767.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 1294312 argD 4676714 argD Neisseria meningitidis FAM18 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_975322.1 1293116 D 272831 CDS YP_975323.1 121635078 4676443 complement(1294415..1295659) 1 NC_008767.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1295659 clpX 4676443 clpX Neisseria meningitidis FAM18 ATP-dependent protease ATP-binding subunit ClpX YP_975323.1 1294415 R 272831 CDS YP_975324.1 121635079 4676504 1295850..1296221 1 NC_008767.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1296221 rbfA 4676504 rbfA Neisseria meningitidis FAM18 ribosome-binding factor A YP_975324.1 1295850 D 272831 CDS YP_975325.1 121635080 4675735 1296227..1297186 1 NC_008767.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1297186 truB 4675735 truB Neisseria meningitidis FAM18 tRNA pseudouridine synthase B YP_975325.1 1296227 D 272831 CDS YP_975326.1 121635081 4675186 1297477..1299711 1 NC_008767.1 type III restriction/modification system modification methylase 1299711 4675186 NMC1310 Neisseria meningitidis FAM18 type III restriction/modification system modification methylase YP_975326.1 1297477 D 272831 CDS YP_975327.1 121635082 4674747 1299659..1302475 1 NC_008767.1 type III restriction/modification system enzyme 1302475 4674747 NMC1311 Neisseria meningitidis FAM18 type III restriction/modification system enzyme YP_975327.1 1299659 D 272831 CDS YP_975328.1 121635083 4675176 complement(1302624..1303796) 1 NC_008767.1 L-lactate dehydrogenase 1303796 lldA 4675176 lldA Neisseria meningitidis FAM18 L-lactate dehydrogenase YP_975328.1 1302624 R 272831 CDS YP_975329.1 121635084 4676382 1304085..1304531 1 NC_008767.1 DNA-binding protein 1304531 4676382 NMC1314 Neisseria meningitidis FAM18 DNA-binding protein YP_975329.1 1304085 D 272831 CDS YP_975330.1 121635085 4676709 1304560..1305774 1 NC_008767.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 1305774 4676709 NMC1315 Neisseria meningitidis FAM18 cysteine desulfurase YP_975330.1 1304560 D 272831 CDS YP_975331.1 121635086 4675142 1306035..1306421 1 NC_008767.1 scaffold protein 1306421 4675142 NMC1317 Neisseria meningitidis FAM18 scaffold protein YP_975331.1 1306035 D 272831 CDS YP_975332.1 121635087 4675141 1306508..1306828 1 NC_008767.1 HesB-like protein 1306828 4675141 NMC1318 Neisseria meningitidis FAM18 HesB-like protein YP_975332.1 1306508 D 272831 CDS YP_975333.1 121635088 4676689 1307091..1307591 1 NC_008767.1 chaperone protein 1307591 hscB 4676689 hscB Neisseria meningitidis FAM18 chaperone protein YP_975333.1 1307091 D 272831 CDS YP_975334.1 121635089 4676464 1307689..1310439 1 NC_008767.1 DNA gyrase subunit A 1310439 gyrA 4676464 gyrA Neisseria meningitidis FAM18 DNA gyrase subunit A YP_975334.1 1307689 D 272831 CDS YP_975335.1 121635090 4676275 1311521..1311712 1 NC_008767.1 transposase (fragment) 1311712 4676275 NMC1323 Neisseria meningitidis FAM18 transposase (fragment) YP_975335.1 1311521 D 272831 CDS YP_975336.1 121635091 4675166 complement(1312043..1312594) 1 NC_008767.1 hypothetical protein 1312594 4675166 NMC1325 Neisseria meningitidis FAM18 hypothetical protein YP_975336.1 1312043 R 272831 CDS YP_975337.1 121635092 4675180 complement(1312608..1314254) 1 NC_008767.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1314254 pgi 4675180 pgi Neisseria meningitidis FAM18 glucose-6-phosphate isomerase YP_975337.1 1312608 R 272831 CDS YP_975338.1 121635093 4676151 complement(1314375..1315259) 1 NC_008767.1 transcriptional regulator 1315259 4676151 NMC1328 Neisseria meningitidis FAM18 transcriptional regulator YP_975338.1 1314375 R 272831 CDS YP_975339.1 121635094 4675161 complement(1315273..1316259) 1 NC_008767.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1316259 glk 4675161 glk Neisseria meningitidis FAM18 glucokinase YP_975339.1 1315273 R 272831 CDS YP_975340.1 121635095 4676606 complement(1316240..1316935) 1 NC_008767.1 6-phosphogluconolactonase 1316935 pgl 4676606 pgl Neisseria meningitidis FAM18 6-phosphogluconolactonase YP_975340.1 1316240 R 272831 CDS YP_975341.1 121635096 4676139 complement(1317215..1318660) 1 NC_008767.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1318660 zwf 4676139 zwf Neisseria meningitidis FAM18 glucose-6-phosphate 1-dehydrogenase YP_975341.1 1317215 R 272831 CDS YP_975342.1 121635097 4676400 1319176..1321011 1 NC_008767.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1321011 edd 4676400 edd Neisseria meningitidis FAM18 phosphogluconate dehydratase YP_975342.1 1319176 D 272831 CDS YP_975343.1 121635098 4675911 1321129..1321830 1 NC_008767.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1321830 eda 4675911 eda Neisseria meningitidis FAM18 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_975343.1 1321129 D 272831 CDS YP_975344.1 121635099 4674743 1323283..1324332 1 NC_008767.1 adenine glycosylase 1324332 mutY 4674743 mutY Neisseria meningitidis FAM18 adenine glycosylase YP_975344.1 1323283 D 272831 CDS YP_975345.1 121635100 4675709 1324749..1325309 1 NC_008767.1 superoxide dismutase 1325309 sodC 4675709 sodC Neisseria meningitidis FAM18 superoxide dismutase YP_975345.1 1324749 D 272831 CDS YP_975346.1 121635101 4675025 complement(1325895..1326395) 1 NC_008767.1 insertion element IS1106 transposase (fragment) 1326395 4675025 NMC1340 Neisseria meningitidis FAM18 insertion element IS1106 transposase (fragment) YP_975346.1 1325895 R 272831 CDS YP_975347.1 121635102 4674822 complement(1326522..1326839) 1 NC_008767.1 remnant of insertion element IS1106A3 transposase 1326839 4674822 NMC1341 Neisseria meningitidis FAM18 remnant of insertion element IS1106A3 transposase YP_975347.1 1326522 R 272831 CDS YP_975348.1 121635103 4674838 complement(1327063..1329291) 1 NC_008767.1 cytolysin secretion ABC transporter 1329291 4674838 NMC1342 Neisseria meningitidis FAM18 cytolysin secretion ABC transporter YP_975348.1 1327063 R 272831 CDS YP_975349.1 121635104 4676235 complement(1329996..1330649) 1 NC_008767.1 insertion element IS1016 transposase 1330649 4676235 NMC1343 Neisseria meningitidis FAM18 insertion element IS1016 transposase YP_975349.1 1329996 R 272831 CDS YP_975350.1 121635105 4676236 1331255..1332070 1 NC_008767.1 RTX iron-regulated frpc protein outer membrane 1332070 4676236 NMC1344 Neisseria meningitidis FAM18 RTX iron-regulated frpc protein outer membrane YP_975350.1 1331255 D 272831 CDS YP_975351.1 121635106 4675356 complement(1338602..1341205) 1 NC_008767.1 aminopeptidase 1341205 pepN 4675356 pepN Neisseria meningitidis FAM18 aminopeptidase YP_975351.1 1338602 R 272831 CDS YP_975352.1 121635107 4675893 complement(1341417..1342211) 1 NC_008767.1 hypothetical protein 1342211 4675893 NMC1348 Neisseria meningitidis FAM18 hypothetical protein YP_975352.1 1341417 R 272831 CDS YP_975353.1 121635108 4675297 complement(1342961..1343830) 1 NC_008767.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1343830 4675297 NMC1351 Neisseria meningitidis FAM18 lipid A biosynthesis lauroyl acyltransferase YP_975353.1 1342961 R 272831 CDS YP_975354.1 121635109 4675298 complement(1343881..1344423) 1 NC_008767.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1344423 ruvC 4675298 ruvC Neisseria meningitidis FAM18 Holliday junction resolvase YP_975354.1 1343881 R 272831 CDS YP_975355.1 121635110 4675120 complement(1344420..1344659) 1 NC_008767.1 Fis family transcriptional regulator 1344659 fis 4675120 fis Neisseria meningitidis FAM18 Fis family transcriptional regulator YP_975355.1 1344420 R 272831 CDS YP_975356.1 121635111 4676678 complement(1344689..1345699) 1 NC_008767.1 hypothetical protein 1345699 4676678 NMC1354 Neisseria meningitidis FAM18 hypothetical protein YP_975356.1 1344689 R 272831 CDS YP_975357.1 121635112 4675946 1345987..1347438 1 NC_008767.1 ATP-dependent RNA helicase 1347438 4675946 NMC1355 Neisseria meningitidis FAM18 ATP-dependent RNA helicase YP_975357.1 1345987 D 272831 CDS YP_975358.1 121635113 4675947 1348134..1349261 1 NC_008767.1 hypothetical protein 1349261 4675947 NMC1357 Neisseria meningitidis FAM18 hypothetical protein YP_975358.1 1348134 D 272831 CDS YP_975359.1 121635114 4675139 1349291..1350169 1 NC_008767.1 hypothetical protein 1350169 4675139 NMC1358 Neisseria meningitidis FAM18 hypothetical protein YP_975359.1 1349291 D 272831 CDS YP_975360.1 121635115 4675140 complement(1350587..1352098) 1 NC_008767.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1352098 lysS 4675140 lysS Neisseria meningitidis FAM18 lysyl-tRNA synthetase YP_975360.1 1350587 R 272831 CDS YP_975361.1 121635116 4676337 complement(1352253..1353506) 1 NC_008767.1 hypothetical protein 1353506 4676337 NMC1362 Neisseria meningitidis FAM18 hypothetical protein YP_975361.1 1352253 R 272831 CDS YP_975362.1 121635117 4675178 1353781..1355760 1 NC_008767.1 aminopeptidase 1355760 4675178 NMC1363 Neisseria meningitidis FAM18 aminopeptidase YP_975362.1 1353781 D 272831 CDS YP_975363.1 121635118 4675179 complement(1356569..1357726) 1 NC_008767.1 porin 1357726 porA 4675179 porA Neisseria meningitidis FAM18 porin YP_975363.1 1356569 R 272831 CDS YP_975364.1 121635119 4676063 complement(1358694..1359170) 1 NC_008767.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1359170 greA 4676063 greA Neisseria meningitidis FAM18 transcription elongation factor GreA YP_975364.1 1358694 R 272831 CDS YP_975365.1 121635120 4676536 1359565..1360866 1 NC_008767.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1360866 aroA 4676536 aroA Neisseria meningitidis FAM18 3-phosphoshikimate 1-carboxyvinyltransferase YP_975365.1 1359565 D 272831 CDS YP_975366.1 121635121 4675591 complement(1360909..1361442) 1 NC_008767.1 lipoprotein 1361442 4675591 NMC1367 Neisseria meningitidis FAM18 lipoprotein YP_975366.1 1360909 R 272831 CDS YP_975367.1 121635122 4675498 complement(1361650..1363227) 1 NC_008767.1 phopholipase D-family protein 1363227 4675498 NMC1368 Neisseria meningitidis FAM18 phopholipase D-family protein YP_975367.1 1361650 R 272831 CDS YP_975368.1 121635123 4675499 complement(1363288..1364796) 1 NC_008767.1 hypothetical protein 1364796 4675499 NMC1370 Neisseria meningitidis FAM18 hypothetical protein YP_975368.1 1363288 R 272831 CDS YP_975369.1 121635124 4675923 1364978..1365757 1 NC_008767.1 hypothetical protein 1365757 4675923 NMC1371 Neisseria meningitidis FAM18 hypothetical protein YP_975369.1 1364978 D 272831 CDS YP_975370.1 121635125 4675924 1365754..1366455 1 NC_008767.1 hypothetical protein 1366455 4675924 NMC1372 Neisseria meningitidis FAM18 hypothetical protein YP_975370.1 1365754 D 272831 CDS YP_975371.1 121635126 4675353 1366452..1367906 1 NC_008767.1 iron-sulfur protein 1367906 4675353 NMC1373 Neisseria meningitidis FAM18 iron-sulfur protein YP_975371.1 1366452 D 272831 CDS YP_975372.1 121635127 4675354 complement(1368089..1368574) 1 NC_008767.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 1368574 purE 4675354 purE Neisseria meningitidis FAM18 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_975372.1 1368089 R 272831 CDS YP_975373.1 121635128 4675367 complement(1368623..1369339) 1 NC_008767.1 hypothetical protein 1369339 4675367 NMC1375 Neisseria meningitidis FAM18 hypothetical protein YP_975373.1 1368623 R 272831 CDS YP_975374.1 121635129 4675357 complement(1369339..1370007) 1 NC_008767.1 methyltransferase 1370007 4675357 NMC1376 Neisseria meningitidis FAM18 methyltransferase YP_975374.1 1369339 R 272831 CDS YP_975375.1 121635130 4675358 1370347..1372323 1 NC_008767.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1372323 mutL 4675358 mutL Neisseria meningitidis FAM18 DNA mismatch repair protein YP_975375.1 1370347 D 272831 CDS YP_975376.1 121635131 4676261 1372418..1374547 1 NC_008767.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1374547 dnaZX 4676261 dnaZX Neisseria meningitidis FAM18 DNA polymerase III subunits gamma and tau YP_975376.1 1372418 D 272831 CDS YP_975377.1 121635132 4675928 1374627..1374962 1 NC_008767.1 hypothetical protein 1374962 4675928 NMC1380 Neisseria meningitidis FAM18 hypothetical protein YP_975377.1 1374627 D 272831 CDS YP_975378.1 121635133 4675523 1377014..1377979 1 NC_008767.1 transposase for IS1655 1377979 4675523 NMC1381 Neisseria meningitidis FAM18 transposase for IS1655 YP_975378.1 1377014 D 272831 CDS YP_975379.1 121635134 4675524 complement(1378364..1379410) 1 NC_008767.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1379410 recA 4675524 recA Neisseria meningitidis FAM18 recombinase A YP_975379.1 1378364 R 272831 CDS YP_975380.1 121635135 4675764 1379631..1380428 1 NC_008767.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1380428 aroD 4675764 aroD Neisseria meningitidis FAM18 3-dehydroquinate dehydratase YP_975380.1 1379631 D 272831 CDS YP_975381.1 121635136 4675502 1380391..1382463 1 NC_008767.1 ATP-dependent DNA helicase 1382463 rep 4675502 rep Neisseria meningitidis FAM18 ATP-dependent DNA helicase YP_975381.1 1380391 D 272831 CDS YP_975382.1 121635137 4675725 complement(1382716..1383774) 1 NC_008767.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1383774 4675725 NMC1386 Neisseria meningitidis FAM18 DNA polymerase IV YP_975382.1 1382716 R 272831 CDS YP_975383.1 121635138 4675451 1385612..1386391 1 NC_008767.1 ferredoxin NADP+ reductase 1386391 4675451 NMC1389 Neisseria meningitidis FAM18 ferredoxin NADP+ reductase YP_975383.1 1385612 D 272831 CDS YP_975384.1 121635139 4675445 complement(1386601..1388013) 1 NC_008767.1 DNA polymerase III subunit 1388013 4675445 NMC1391 Neisseria meningitidis FAM18 DNA polymerase III subunit YP_975384.1 1386601 R 272831 CDS YP_975385.1 121635140 4675446 1388831..1390006 1 NC_008767.1 hypothetical protein 1390006 4675446 NMC1392 Neisseria meningitidis FAM18 hypothetical protein YP_975385.1 1388831 D 272831 CDS YP_975386.1 121635141 4675369 complement(1390217..1390765) 1 NC_008767.1 hypothetical protein 1390765 4675369 NMC1393 Neisseria meningitidis FAM18 hypothetical protein YP_975386.1 1390217 R 272831 CDS YP_975387.1 121635142 4675370 complement(1390768..1392264) 1 NC_008767.1 ferredoxin 1392264 4675370 NMC1394 Neisseria meningitidis FAM18 ferredoxin YP_975387.1 1390768 R 272831 CDS YP_975388.1 121635143 4675506 1392793..1394772 1 NC_008767.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1394772 tkt 4675506 tkt Neisseria meningitidis FAM18 transketolase YP_975388.1 1392793 D 272831 CDS YP_975389.1 121635144 4675194 1394920..1396308 1 NC_008767.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1396308 fumC 4675194 fumC Neisseria meningitidis FAM18 fumarate hydratase YP_975389.1 1394920 D 272831 CDS YP_975390.1 121635145 4676647 complement(1396373..1397296) 1 NC_008767.1 hypothetical protein 1397296 4676647 NMC1397 Neisseria meningitidis FAM18 hypothetical protein YP_975390.1 1396373 R 272831 CDS YP_975391.1 121635146 4675507 complement(1397821..1398345) 1 NC_008767.1 ssDNA-binding protein 1398345 ssb 4675507 ssb Neisseria meningitidis FAM18 ssDNA-binding protein YP_975391.1 1397821 R 272831 CDS YP_975392.1 121635147 4675007 complement(1398349..1399734) 1 NC_008767.1 integral membrane transporter 1399734 4675007 NMC1400 Neisseria meningitidis FAM18 integral membrane transporter YP_975392.1 1398349 R 272831 CDS YP_975393.1 121635148 4675496 complement(1399842..1400465) 1 NC_008767.1 transglycosylase 1400465 4675496 NMC1401 Neisseria meningitidis FAM18 transglycosylase YP_975393.1 1399842 R 272831 CDS YP_975394.1 121635149 4675497 complement(1401610..1402101) 1 NC_008767.1 hypothetical protein 1402101 4675497 NMC1402 Neisseria meningitidis FAM18 hypothetical protein YP_975394.1 1401610 R 272831 CDS YP_975395.1 121635150 4675483 complement(1403533..1404333) 1 NC_008767.1 hypothetical protein 1404333 opaA 4675483 opaA Neisseria meningitidis FAM18 hypothetical protein YP_975395.1 1403533 R 272831 CDS YP_975396.1 121635151 4676167 1405344..1406075 1 NC_008767.1 hypothetical protein 1406075 4676167 NMC1404 Neisseria meningitidis FAM18 hypothetical protein YP_975396.1 1405344 D 272831 CDS YP_975397.1 121635152 4675484 1406192..1407700 1 NC_008767.1 exopolyphosphatase 1407700 4675484 NMC1405 Neisseria meningitidis FAM18 exopolyphosphatase YP_975397.1 1406192 D 272831 CDS YP_975398.1 121635153 4676368 complement(1408594..1408935) 1 NC_008767.1 hypothetical protein 1408935 4676368 NMC1407 Neisseria meningitidis FAM18 hypothetical protein YP_975398.1 1408594 R 272831 CDS YP_975399.1 121635154 4676369 complement(1408941..1409951) 1 NC_008767.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1409951 trpS 4676369 trpS Neisseria meningitidis FAM18 tryptophanyl-tRNA synthetase YP_975399.1 1408941 R 272831 CDS YP_975400.1 121635155 4674814 1410212..1412791 1 NC_008767.1 ClpB protein 1412791 clpB 4674814 clpB Neisseria meningitidis FAM18 ClpB protein YP_975400.1 1410212 D 272831 CDS YP_975401.1 121635156 4676695 complement(1412878..1414092) 1 NC_008767.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 1414092 4676695 NMC1410 Neisseria meningitidis FAM18 aminotransferase YP_975401.1 1412878 R 272831 CDS YP_975402.1 121635157 4676366 complement(1414181..1414390) 1 NC_008767.1 tautomerase 1414390 4676366 NMC1411 Neisseria meningitidis FAM18 tautomerase YP_975402.1 1414181 R 272831 CDS YP_975403.1 121635158 4676367 1414735..1415541 1 NC_008767.1 hypothetical protein 1415541 4676367 NMC1412 Neisseria meningitidis FAM18 hypothetical protein YP_975403.1 1414735 D 272831 CDS YP_975404.1 121635159 4675519 complement(1415599..1416864) 1 NC_008767.1 glutamate dehydrogenase 1416864 4675519 NMC1413 Neisseria meningitidis FAM18 glutamate dehydrogenase YP_975404.1 1415599 R 272831 CDS YP_975405.1 121635160 4675520 1417271..1417981 1 NC_008767.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 1417981 4675520 NMC1414 Neisseria meningitidis FAM18 phosphoglycolate phosphatase YP_975405.1 1417271 D 272831 CDS YP_975406.1 121635161 4675651 1418054..1418515 1 NC_008767.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1418515 recX 4675651 recX Neisseria meningitidis FAM18 recombination regulator RecX YP_975406.1 1418054 D 272831 CDS YP_975407.1 121635162 4675652 1418903..1419385 1 NC_008767.1 acyl-CoA hydrolase 1419385 4675652 NMC1417 Neisseria meningitidis FAM18 acyl-CoA hydrolase YP_975407.1 1418903 D 272831 CDS YP_975408.1 121635163 4675168 complement(1419745..1420992) 1 NC_008767.1 membrane peptidase 1420992 4675168 NMC1418 Neisseria meningitidis FAM18 membrane peptidase YP_975408.1 1419745 R 272831 CDS YP_975409.1 121635164 4675169 complement(1421248..1421994) 1 NC_008767.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 1421994 surE 4675169 surE Neisseria meningitidis FAM18 stationary phase survival protein SurE YP_975409.1 1421248 R 272831 CDS YP_975410.1 121635165 4675210 complement(1422011..1423567) 1 NC_008767.1 hypothetical protein 1423567 4675210 NMC1420 Neisseria meningitidis FAM18 hypothetical protein YP_975410.1 1422011 R 272831 CDS YP_975411.1 121635166 4675616 complement(1423935..1424723) 1 NC_008767.1 fimbrial assembly protein 1424723 4675616 NMC1422 Neisseria meningitidis FAM18 fimbrial assembly protein YP_975411.1 1423935 R 272831 CDS YP_975412.1 121635167 4675617 complement(1424832..1426265) 1 NC_008767.1 succinate semialdehyde dehydrogenase 1426265 gabD 4675617 gabD Neisseria meningitidis FAM18 succinate semialdehyde dehydrogenase YP_975412.1 1424832 R 272831 CDS YP_975413.1 121635168 4676669 1426906..1427235 1 NC_008767.1 hypothetical protein 1427235 4676669 NMC1424 Neisseria meningitidis FAM18 hypothetical protein YP_975413.1 1426906 D 272831 CDS YP_975414.1 121635169 4675534 complement(1427368..1427748) 1 NC_008767.1 lipoprotein 1427748 4675534 NMC1425 Neisseria meningitidis FAM18 lipoprotein YP_975414.1 1427368 R 272831 CDS YP_975415.1 121635170 4675535 1428224..1430305 1 NC_008767.1 integral membrane protein (CstA-like) 1430305 4675535 NMC1426 Neisseria meningitidis FAM18 integral membrane protein (CstA-like) YP_975415.1 1428224 D 272831 CDS YP_975416.1 121635171 4675508 1431830..1434595 1 NC_008767.1 outer membrane substrate binding protein 1434595 4675508 NMC1428 Neisseria meningitidis FAM18 outer membrane substrate binding protein YP_975416.1 1431830 D 272831 CDS YP_975417.1 121635172 4675509 complement(1436088..1437305) 1 NC_008767.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1437305 lysC 4675509 lysC Neisseria meningitidis FAM18 aspartate kinase YP_975417.1 1436088 R 272831 CDS YP_975418.1 121635173 4676336 complement(1437507..1438235) 1 NC_008767.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1438235 rph 4676336 rph Neisseria meningitidis FAM18 ribonuclease PH YP_975418.1 1437507 R 272831 CDS YP_975419.1 121635174 4675412 complement(1438317..1438781) 1 NC_008767.1 hypothetical protein 1438781 4675412 NMC1431 Neisseria meningitidis FAM18 hypothetical protein YP_975419.1 1438317 R 272831 CDS YP_975420.1 121635175 4675525 1438998..1439774 1 NC_008767.1 hypothetical protein 1439774 4675525 NMC1432 Neisseria meningitidis FAM18 hypothetical protein YP_975420.1 1438998 D 272831 CDS YP_975421.1 121635176 4675526 1440019..1440873 1 NC_008767.1 hypothetical protein 1440873 4675526 NMC1433 Neisseria meningitidis FAM18 hypothetical protein YP_975421.1 1440019 D 272831 CDS YP_975422.1 121635177 4675561 1440863..1442122 1 NC_008767.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1442122 pncB 4675561 pncB Neisseria meningitidis FAM18 nicotinate phosphoribosyltransferase YP_975422.1 1440863 D 272831 CDS YP_975423.1 121635178 4675953 1442214..1443932 1 NC_008767.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1443932 argS 4675953 argS Neisseria meningitidis FAM18 arginyl-tRNA synthetase YP_975423.1 1442214 D 272831 CDS YP_975424.1 121635179 4676240 1444447..1445904 1 NC_008767.1 hypothetical protein 1445904 4676240 NMC1437 Neisseria meningitidis FAM18 hypothetical protein YP_975424.1 1444447 D 272831 CDS YP_975425.1 121635180 4675562 complement(1446841..1447587) 1 NC_008767.1 binding-protein-dependent transport systems inner membrane protein 1447587 4675562 NMC1438 Neisseria meningitidis FAM18 binding-protein-dependent transport systems inner membrane protein YP_975425.1 1446841 R 272831 CDS YP_975426.1 121635181 4675628 complement(1447766..1448467) 1 NC_008767.1 nuclease 1448467 4675628 NMC1439 Neisseria meningitidis FAM18 nuclease YP_975426.1 1447766 R 272831 CDS YP_975427.1 121635182 4675629 complement(1448506..1449177) 1 NC_008767.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1449177 rpiA 4675629 rpiA Neisseria meningitidis FAM18 ribose-5-phosphate isomerase A YP_975427.1 1448506 R 272831 CDS YP_975428.1 121635183 4675402 complement(1449254..1449736) 1 NC_008767.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1449736 ispF 4675402 ispF Neisseria meningitidis FAM18 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_975428.1 1449254 R 272831 CDS YP_975429.1 121635184 4675569 complement(1449768..1450457) 1 NC_008767.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1450457 ispD 4675569 ispD Neisseria meningitidis FAM18 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_975429.1 1449768 R 272831 CDS YP_975430.1 121635185 4675570 complement(1450454..1451215) 1 NC_008767.1 DNA polymerase III subunit epsilon 1451215 dnaQ 4675570 dnaQ Neisseria meningitidis FAM18 DNA polymerase III subunit epsilon YP_975430.1 1450454 R 272831 CDS YP_975431.1 121635186 4675926 complement(1451346..1452656) 1 NC_008767.1 hypothetical protein 1452656 4675926 NMC1444 Neisseria meningitidis FAM18 hypothetical protein YP_975431.1 1451346 R 272831 CDS YP_975432.1 121635187 4675653 complement(1452646..1452834) 1 NC_008767.1 hypothetical protein 1452834 4675653 NMC1445 Neisseria meningitidis FAM18 hypothetical protein YP_975432.1 1452646 R 272831 CDS YP_975433.1 121635188 4675654 complement(1452831..1453130) 1 NC_008767.1 hypothetical protein 1453130 4675654 NMC1446 Neisseria meningitidis FAM18 hypothetical protein YP_975433.1 1452831 R 272831 CDS YP_975434.1 121635189 4675571 1453451..1454677 1 NC_008767.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1454677 ackA1 4675571 ackA1 Neisseria meningitidis FAM18 acetate kinase YP_975434.1 1453451 D 272831 CDS YP_975435.1 121635190 4676166 complement(1455193..1457034) 1 NC_008767.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 1457034 dipZ 4676166 dipZ Neisseria meningitidis FAM18 thiol:disulfide interchange protein YP_975435.1 1455193 R 272831 CDS YP_975436.1 121635191 4675572 1457125..1457595 1 NC_008767.1 hypothetical protein 1457595 4675572 NMC1449 Neisseria meningitidis FAM18 hypothetical protein YP_975436.1 1457125 D 272831 CDS YP_975437.1 121635192 4675144 complement(1457666..1458493) 1 NC_008767.1 transferase 1458493 4675144 NMC1450 Neisseria meningitidis FAM18 transferase YP_975437.1 1457666 R 272831 CDS YP_975438.1 121635193 4675145 complement(1458565..1459047) 1 NC_008767.1 peptidyl-prolyl isomerase 1459047 4675145 NMC1451 Neisseria meningitidis FAM18 peptidyl-prolyl isomerase YP_975438.1 1458565 R 272831 CDS YP_975439.1 121635194 4676566 1459536..1459853 1 NC_008767.1 hypothetical protein 1459853 4676566 NMC1452 Neisseria meningitidis FAM18 hypothetical protein YP_975439.1 1459536 D 272831 CDS YP_975440.1 121635195 4676567 1459911..1461278 1 NC_008767.1 hypothetical protein 1461278 4676567 NMC1453 Neisseria meningitidis FAM18 hypothetical protein YP_975440.1 1459911 D 272831 CDS YP_975441.1 121635196 4676559 complement(join(1461459..1463300,1463299..1463403)) 1 NC_008767.1 virulence associated protein 1463403 4676559 NMC1454 Neisseria meningitidis FAM18 virulence associated protein YP_975441.1 1461459 R 272831 CDS YP_975442.1 121635197 4676560 complement(1463876..1464328) 1 NC_008767.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1464328 smpB 4676560 smpB Neisseria meningitidis FAM18 SsrA-binding protein YP_975442.1 1463876 R 272831 CDS YP_975443.1 121635198 4675030 complement(1464377..1465387) 1 NC_008767.1 ADP-heptose--LPS heptosyltransferase 1465387 rfaF 4675030 rfaF Neisseria meningitidis FAM18 ADP-heptose--LPS heptosyltransferase YP_975443.1 1464377 R 272831 CDS YP_975444.1 121635199 4675733 complement(1465970..1466839) 1 NC_008767.1 methylated-DNA-protein-cysteine methyltransferase 1466839 4675733 NMC1457 Neisseria meningitidis FAM18 methylated-DNA-protein-cysteine methyltransferase YP_975444.1 1465970 R 272831 CDS YP_975445.1 121635200 4676690 1466997..1467557 1 NC_008767.1 hypothetical protein 1467557 4676690 NMC1458 Neisseria meningitidis FAM18 hypothetical protein YP_975445.1 1466997 D 272831 CDS YP_975446.1 121635201 4676691 complement(1468297..1469442) 1 NC_008767.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1469442 dapE 4676691 dapE Neisseria meningitidis FAM18 succinyl-diaminopimelate desuccinylase YP_975446.1 1468297 R 272831 CDS YP_975447.1 121635202 4675962 complement(1469555..1470175) 1 NC_008767.1 hypothetical protein 1470175 4675962 NMC1460 Neisseria meningitidis FAM18 hypothetical protein YP_975447.1 1469555 R 272831 CDS YP_975448.1 121635203 4676613 complement(1470209..1470739) 1 NC_008767.1 hypothetical protein 1470739 4676613 NMC1461 Neisseria meningitidis FAM18 hypothetical protein YP_975448.1 1470209 R 272831 CDS YP_975449.1 121635204 4676614 complement(1470813..1471418) 1 NC_008767.1 hypothetical protein 1471418 4676614 NMC1462 Neisseria meningitidis FAM18 hypothetical protein YP_975449.1 1470813 R 272831 CDS YP_975450.1 121635205 4676639 1472198..1474948 1 NC_008767.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1474948 secA 4676639 secA Neisseria meningitidis FAM18 preprotein translocase subunit SecA YP_975450.1 1472198 D 272831 CDS YP_975451.1 121635206 4675103 1475094..1476866 1 NC_008767.1 synthesizes RNA primers at the replication forks; DNA primase 1476866 dnaG 4675103 dnaG Neisseria meningitidis FAM18 DNA primase YP_975451.1 1475094 D 272831 CDS YP_975452.1 121635207 4675958 1477006..1478982 1 NC_008767.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1478982 rpoD 4675958 rpoD Neisseria meningitidis FAM18 RNA polymerase sigma factor RpoD YP_975452.1 1477006 D 272831 CDS YP_975453.1 121635208 4676640 complement(1481777..1484608) 1 NC_008767.1 lactoferrin binding protein A 1484608 lbpA 4676640 lbpA Neisseria meningitidis FAM18 lactoferrin binding protein A YP_975453.1 1481777 R 272831 CDS YP_975454.1 121635209 4676403 complement(1484605..1486782) 1 NC_008767.1 lactoferrin-binding protein 1486782 lbpB 4676403 lbpB Neisseria meningitidis FAM18 lactoferrin-binding protein YP_975454.1 1484605 R 272831 CDS YP_975455.1 121635210 4676404 complement(1489378..1489662) 1 NC_008767.1 it misses that part: MSTFFRQTAQA, when compared to the homologous sequences, but there is a substitution of M -> R, thus cannot be extended; remnant of transposase from insertion element IS1106A2 (fragment) 1489662 4676404 NMC1470 Neisseria meningitidis FAM18 remnant of transposase from insertion element IS1106A2 (fragment) YP_975455.1 1489378 R 272831 CDS YP_975456.1 121635211 4676653 complement(1489911..1491545) 1 NC_008767.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1491545 pyrG 4676653 pyrG Neisseria meningitidis FAM18 CTP synthetase YP_975456.1 1489911 R 272831 CDS YP_975457.1 121635212 4675778 complement(1491657..1493327) 1 NC_008767.1 long-chain-fatty-acid--CoA-ligase 1493327 fadD 4675778 fadD Neisseria meningitidis FAM18 long-chain-fatty-acid--CoA-ligase YP_975457.1 1491657 R 272831 CDS YP_975458.1 121635213 4675275 complement(1493398..1494501) 1 NC_008767.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1494501 mnmA 4675275 mnmA Neisseria meningitidis FAM18 tRNA-specific 2-thiouridylase MnmA YP_975458.1 1493398 R 272831 CDS YP_975459.1 121635214 4674832 complement(1494627..1495100) 1 NC_008767.1 hypothetical protein 1495100 4674832 NMC1474 Neisseria meningitidis FAM18 hypothetical protein YP_975459.1 1494627 R 272831 CDS YP_975460.1 121635215 4676654 complement(1495215..1495598) 1 NC_008767.1 diacylglycerol kinase 1495598 dgk 4676654 dgk Neisseria meningitidis FAM18 diacylglycerol kinase YP_975460.1 1495215 R 272831 CDS YP_975461.1 121635216 4675968 complement(1495910..1496869) 1 NC_008767.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 1496869 gshB 4675968 gshB Neisseria meningitidis FAM18 glutathione synthetase YP_975461.1 1495910 R 272831 CDS YP_975462.1 121635217 4676512 complement(1496959..1498680) 1 NC_008767.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1498680 glnS 4676512 glnS Neisseria meningitidis FAM18 glutaminyl-tRNA synthetase YP_975462.1 1496959 R 272831 CDS YP_975463.1 121635218 4676603 complement(1498759..1499532) 1 NC_008767.1 glycerol 3-phosphate regulon repressor 1499532 glpR 4676603 glpR Neisseria meningitidis FAM18 glycerol 3-phosphate regulon repressor YP_975463.1 1498759 R 272831 CDS YP_975464.1 121635219 4676598 complement(1499575..1500477) 1 NC_008767.1 hypothetical protein 1500477 4676598 NMC1480 Neisseria meningitidis FAM18 hypothetical protein YP_975464.1 1499575 R 272831 CDS YP_975465.1 121635220 4675639 complement(1500626..1501342) 1 NC_008767.1 GntR family transcriptional regulator 1501342 4675639 NMC1481 Neisseria meningitidis FAM18 GntR family transcriptional regulator YP_975465.1 1500626 R 272831 CDS YP_975466.1 121635221 4675640 complement(1501911..1502333) 1 NC_008767.1 hypothetical protein 1502333 4675640 NMC1483 Neisseria meningitidis FAM18 hypothetical protein YP_975466.1 1501911 R 272831 CDS YP_975467.1 121635222 4676587 complement(1502451..1503122) 1 NC_008767.1 hypothetical protein 1503122 4676587 NMC1485 Neisseria meningitidis FAM18 hypothetical protein YP_975467.1 1502451 R 272831 CDS YP_975468.1 121635223 4676588 complement(1503138..1503764) 1 NC_008767.1 phosphoribosylglycinamide transformylase 1503764 purN 4676588 purN Neisseria meningitidis FAM18 phosphoribosylglycinamide transformylase YP_975468.1 1503138 R 272831 CDS YP_975469.1 121635224 4676029 complement(1503871..1504677) 1 NC_008767.1 peptidyl-prolyl isomerase 1504677 4676029 NMC1487 Neisseria meningitidis FAM18 peptidyl-prolyl isomerase YP_975469.1 1503871 R 272831 CDS YP_975470.1 121635225 4675641 complement(1504936..1505376) 1 NC_008767.1 DNA polymerase III subunit chi 1505376 holC 4675641 holC Neisseria meningitidis FAM18 DNA polymerase III subunit chi YP_975470.1 1504936 R 272831 CDS YP_975471.1 121635226 4676421 complement(1505439..1506845) 1 NC_008767.1 aminopeptidase 1506845 pepA 4676421 pepA Neisseria meningitidis FAM18 aminopeptidase YP_975471.1 1505439 R 272831 CDS YP_975472.1 121635227 4676106 1507015..1508130 1 NC_008767.1 hypothetical protein 1508130 4676106 NMC1490 Neisseria meningitidis FAM18 hypothetical protein YP_975472.1 1507015 D 272831 CDS YP_975473.1 121635228 4675642 1508127..1509197 1 NC_008767.1 hypothetical protein 1509197 4675642 NMC1491 Neisseria meningitidis FAM18 hypothetical protein YP_975473.1 1508127 D 272831 CDS YP_975474.1 121635229 4675831 1509508..1512093 1 NC_008767.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 1512093 acnB 4675831 acnB Neisseria meningitidis FAM18 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_975474.1 1509508 D 272831 CDS YP_975475.1 121635230 4675347 1512235..1513230 1 NC_008767.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 1513230 argF 4675347 argF Neisseria meningitidis FAM18 ornithine carbamoyltransferase YP_975475.1 1512235 D 272831 CDS YP_975476.1 121635231 4676444 complement(1513454..1514467) 1 NC_008767.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1514467 ilvC 4676444 ilvC Neisseria meningitidis FAM18 ketol-acid reductoisomerase YP_975476.1 1513454 R 272831 CDS YP_975477.1 121635232 4676442 complement(1514547..1514840) 1 NC_008767.1 hypothetical protein 1514840 4676442 NMC1495 Neisseria meningitidis FAM18 hypothetical protein YP_975477.1 1514547 R 272831 CDS YP_975478.1 121635233 4675832 complement(1514907..1515398) 1 NC_008767.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1515398 ilvH 4675832 ilvH Neisseria meningitidis FAM18 acetolactate synthase 3 regulatory subunit YP_975478.1 1514907 R 272831 CDS YP_975479.1 121635234 4676427 complement(1515409..1517136) 1 NC_008767.1 acetolactate synthase isozyme III large subunit 1517136 ilvI 4676427 ilvI Neisseria meningitidis FAM18 acetolactate synthase isozyme III large subunit YP_975479.1 1515409 R 272831 CDS YP_975480.1 121635235 4676428 1518257..1518910 1 NC_008767.1 lipoprotein 1518910 4676428 NMC1498 Neisseria meningitidis FAM18 lipoprotein YP_975480.1 1518257 D 272831 CDS YP_975481.1 121635236 4675655 1518989..1519642 1 NC_008767.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 1519642 hisG 4675655 hisG Neisseria meningitidis FAM18 ATP phosphoribosyltransferase YP_975481.1 1518989 D 272831 CDS YP_975482.1 121635237 4676429 1519746..1520645 1 NC_008767.1 hypothetical protein 1520645 4676429 NMC1500 Neisseria meningitidis FAM18 hypothetical protein YP_975482.1 1519746 D 272831 CDS YP_975483.1 121635238 4675656 1520642..1521931 1 NC_008767.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1521931 hisD 4675656 hisD Neisseria meningitidis FAM18 histidinol dehydrogenase YP_975483.1 1520642 D 272831 CDS YP_975484.1 121635239 4676432 1521977..1523074 1 NC_008767.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1523074 hisC 4676432 hisC Neisseria meningitidis FAM18 histidinol-phosphate aminotransferase YP_975484.1 1521977 D 272831 CDS YP_975485.2 229270472 4676431 1523254..1523988 1 NC_008767.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1523988 hisB 4676431 hisB Neisseria meningitidis FAM18 imidazoleglycerol-phosphate dehydratase YP_975485.2 1523254 D 272831 CDS YP_975486.1 121635241 4676477 1524083..1524952 1 NC_008767.1 hypothetical protein 1524952 4676477 NMC1504 Neisseria meningitidis FAM18 hypothetical protein YP_975486.1 1524083 D 272831 CDS YP_975487.1 121635242 4675649 1525230..1525592 1 NC_008767.1 transcriptional regulator 1525592 4675649 NMC1505 Neisseria meningitidis FAM18 transcriptional regulator YP_975487.1 1525230 D 272831 CDS YP_975488.1 121635243 4675650 1525623..1526627 1 NC_008767.1 transposase for IS1106A3 1526627 4675650 NMC1506 Neisseria meningitidis FAM18 transposase for IS1106A3 YP_975488.1 1525623 D 272831 CDS YP_975489.1 121635244 4675815 1526895..1527758 1 NC_008767.1 hypothetical protein 1527758 4675815 NMC1507 Neisseria meningitidis FAM18 hypothetical protein YP_975489.1 1526895 D 272831 CDS YP_975490.1 121635245 4675816 complement(1527809..1528861) 1 NC_008767.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1528861 4675816 NMC1508 Neisseria meningitidis FAM18 periplasmic protease YP_975490.1 1527809 R 272831 CDS YP_975491.1 121635246 4675637 complement(1529708..1530271) 1 NC_008767.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1530271 pgsA 4675637 pgsA Neisseria meningitidis FAM18 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_975491.1 1529708 R 272831 CDS YP_975492.1 121635247 4676041 complement(1530498..1530800) 1 NC_008767.1 hypothetical protein 1530800 4676041 NMC1511 Neisseria meningitidis FAM18 hypothetical protein YP_975492.1 1530498 R 272831 CDS YP_975493.1 121635248 4675638 complement(1531131..1531466) 1 NC_008767.1 hypothetical protein 1531466 4675638 NMC1512 Neisseria meningitidis FAM18 hypothetical protein YP_975493.1 1531131 R 272831 CDS YP_975494.1 121635249 4675761 1531595..1532500 1 NC_008767.1 AraC family transcriptional regulator 1532500 4675761 NMC1513 Neisseria meningitidis FAM18 AraC family transcriptional regulator YP_975494.1 1531595 D 272831 CDS YP_975495.1 121635250 4675762 complement(1532562..1533137) 1 NC_008767.1 hypothetical protein 1533137 4675762 NMC1514 Neisseria meningitidis FAM18 hypothetical protein YP_975495.1 1532562 R 272831 CDS YP_975496.1 121635251 4675750 1533197..1534099 1 NC_008767.1 hypothetical protein 1534099 4675750 NMC1515 Neisseria meningitidis FAM18 hypothetical protein YP_975496.1 1533197 D 272831 CDS YP_975497.1 121635252 4675751 complement(1534140..1535270) 1 NC_008767.1 polyamine permease substrate-binding protein 1535270 4675751 NMC1516 Neisseria meningitidis FAM18 polyamine permease substrate-binding protein YP_975497.1 1534140 R 272831 CDS YP_975498.1 121635253 4675666 1535475..1538099 1 NC_008767.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1538099 alaS 4675666 alaS Neisseria meningitidis FAM18 alanyl-tRNA synthetase YP_975498.1 1535475 D 272831 CDS YP_975499.1 121635254 4676384 complement(1538188..1539210) 1 NC_008767.1 hypothetical protein 1539210 4676384 NMC1519 Neisseria meningitidis FAM18 hypothetical protein YP_975499.1 1538188 R 272831 CDS YP_975500.1 121635255 4675667 complement(1539264..1540415) 1 NC_008767.1 C-5 cytosine-specific DNA methylase 1540415 4675667 NMC1520 Neisseria meningitidis FAM18 C-5 cytosine-specific DNA methylase YP_975500.1 1539264 R 272831 CDS YP_975501.1 121635256 4675768 1543413..1544357 1 NC_008767.1 potassium-tellurite ethidium and proflavin transporter 1544357 4675768 NMC1523 Neisseria meningitidis FAM18 potassium-tellurite ethidium and proflavin transporter YP_975501.1 1543413 D 272831 CDS YP_975502.1 121635257 4675769 complement(1544431..1545114) 1 NC_008767.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1545114 gpmA 4675769 gpmA Neisseria meningitidis FAM18 phosphoglyceromutase YP_975502.1 1544431 R 272831 CDS YP_975503.1 121635258 4676521 1545417..1547714 1 NC_008767.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1547714 parC 4676521 parC Neisseria meningitidis FAM18 DNA topoisomerase IV subunit A YP_975503.1 1545417 D 272831 CDS YP_975504.1 121635259 4676174 1547734..1549251 1 NC_008767.1 two component sensor kinase 1549251 4676174 NMC1526 Neisseria meningitidis FAM18 two component sensor kinase YP_975504.1 1547734 D 272831 CDS YP_975505.1 121635260 4675720 1549303..1549770 1 NC_008767.1 two component response regulator 1549770 4675720 NMC1527 Neisseria meningitidis FAM18 two component response regulator YP_975505.1 1549303 D 272831 CDS YP_975506.1 121635261 4675721 1549874..1550626 1 NC_008767.1 hypothetical protein 1550626 4675721 NMC1528 Neisseria meningitidis FAM18 hypothetical protein YP_975506.1 1549874 D 272831 CDS YP_975507.1 121635262 4675833 complement(1552367..1553536) 1 NC_008767.1 O-succinylhomoserine sulfhydrolase 1553536 metZ 4675833 metZ Neisseria meningitidis FAM18 O-succinylhomoserine sulfhydrolase YP_975507.1 1552367 R 272831 CDS YP_975508.1 121635263 4676273 complement(1553834..1554595) 1 NC_008767.1 hypothetical protein 1554595 4676273 NMC1531 Neisseria meningitidis FAM18 hypothetical protein YP_975508.1 1553834 R 272831 CDS YP_975509.1 121635264 4675834 1554695..1554946 1 NC_008767.1 hypothetical protein 1554946 4675834 NMC1532 Neisseria meningitidis FAM18 hypothetical protein YP_975509.1 1554695 D 272831 CDS YP_975510.1 121635265 4675807 1554998..1555804 1 NC_008767.1 histidine-binding periplasmic protein 1555804 hisJ 4675807 hisJ Neisseria meningitidis FAM18 histidine-binding periplasmic protein YP_975510.1 1554998 D 272831 CDS YP_975511.1 121635266 4676453 1555994..1557634 1 NC_008767.1 fumarate hydratase 1557634 fumA 4676453 fumA Neisseria meningitidis FAM18 fumarate hydratase YP_975511.1 1555994 D 272831 CDS YP_975512.1 121635267 4676636 1557732..1559144 1 NC_008767.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1559144 trkA 4676636 trkA Neisseria meningitidis FAM18 potassium transporter peripheral membrane protein YP_975512.1 1557732 D 272831 CDS YP_975513.1 121635268 4675191 complement(1559477..1560364) 1 NC_008767.1 insertion element is1655 transposase (fragment) 1560364 4675191 NMC1536 Neisseria meningitidis FAM18 insertion element is1655 transposase (fragment) YP_975513.1 1559477 R 272831 CDS YP_975514.1 121635269 4675808 complement(1561494..1562300) 1 NC_008767.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1562300 thiD 4675808 thiD Neisseria meningitidis FAM18 phosphomethylpyrimidine kinase YP_975514.1 1561494 R 272831 CDS YP_975515.1 121635270 4675718 1564531..1564968 1 NC_008767.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1564968 rnhA 4675718 rnhA Neisseria meningitidis FAM18 ribonuclease H YP_975515.1 1564531 D 272831 CDS YP_975516.1 121635271 4675574 1566542..1566946 1 NC_008767.1 hypothetical protein 1566946 4675574 NMC1545 Neisseria meningitidis FAM18 hypothetical protein YP_975516.1 1566542 D 272831 CDS YP_975517.1 121635272 4675719 1566986..1568170 1 NC_008767.1 hypothetical protein 1568170 4675719 NMC1546 Neisseria meningitidis FAM18 hypothetical protein YP_975517.1 1566986 D 272831 CDS YP_975518.1 121635273 4675792 complement(1568233..1568766) 1 NC_008767.1 glutathione peroxidase 1568766 gpxA 4675792 gpxA Neisseria meningitidis FAM18 glutathione peroxidase YP_975518.1 1568233 R 272831 CDS YP_975519.1 121635274 4676535 complement(join(1568945..1570915,1570919..1571200)) 1 NC_008767.1 nitric oxide reductase 1571200 nor 4676535 nor Neisseria meningitidis FAM18 nitric oxide reductase YP_975519.1 1568945 R 272831 CDS YP_975520.1 121635275 4676222 join(1571574..1571825,1571825..1572733) 1 NC_008767.1 nitrite reductase, major outer membrane copper-containing protein 1572733 aniA 4676222 aniA Neisseria meningitidis FAM18 nitrite reductase, major outer membrane copper-containing protein YP_975520.1 1571574 D 272831 CDS YP_975521.1 121635276 4676465 1572858..1573613 1 NC_008767.1 hypothetical protein 1573613 4676465 NMC1550 Neisseria meningitidis FAM18 hypothetical protein YP_975521.1 1572858 D 272831 CDS YP_975522.1 121635277 4675793 join(1574776..1574811,1574811..1575569) 1 NC_008767.1 hypothetical protein 1575569 opaB 4675793 opaB Neisseria meningitidis FAM18 hypothetical protein YP_975522.1 1574776 D 272831 CDS YP_975523.1 121635278 4676168 complement(1575770..1576327) 1 NC_008767.1 hypothetical protein 1576327 4676168 NMC1552 Neisseria meningitidis FAM18 hypothetical protein YP_975523.1 1575770 R 272831 CDS YP_975524.1 121635279 4675825 complement(1576403..1578037) 1 NC_008767.1 hypothetical protein 1578037 4675825 NMC1553 Neisseria meningitidis FAM18 hypothetical protein YP_975524.1 1576403 R 272831 CDS YP_975525.1 121635280 4675826 complement(1578318..1579424) 1 NC_008767.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1579424 serC 4675826 serC Neisseria meningitidis FAM18 phosphoserine aminotransferase YP_975525.1 1578318 R 272831 CDS YP_975526.1 121635281 4675093 1579789..1580220 1 NC_008767.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1580220 4675093 NMC1555 Neisseria meningitidis FAM18 hypothetical protein YP_975526.1 1579789 D 272831 CDS YP_975527.1 121635282 4675993 1580233..1581750 1 NC_008767.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1581750 nusA 4675993 nusA Neisseria meningitidis FAM18 transcription elongation factor NusA YP_975527.1 1580233 D 272831 CDS YP_975528.1 121635283 4676182 1581762..1584650 1 NC_008767.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1584650 infB 4676182 infB Neisseria meningitidis FAM18 translation initiation factor IF-2 YP_975528.1 1581762 D 272831 CDS YP_975529.1 121635284 4675972 complement(1584862..1586256) 1 NC_008767.1 hypothetical protein 1586256 4675972 NMC1558 Neisseria meningitidis FAM18 hypothetical protein YP_975529.1 1584862 R 272831 CDS YP_975530.1 121635285 4675994 complement(1586330..1587670) 1 NC_008767.1 hypothetical protein 1587670 4675994 NMC1559 Neisseria meningitidis FAM18 hypothetical protein YP_975530.1 1586330 R 272831 CDS YP_975531.1 121635286 4675819 1587813..1588439 1 NC_008767.1 hemolysin 1588439 4675819 NMC1560 Neisseria meningitidis FAM18 hemolysin YP_975531.1 1587813 D 272831 CDS YP_975532.1 121635287 4675820 complement(1588503..1589921) 1 NC_008767.1 sodium:alanine symporter 1589921 4675820 NMC1562 Neisseria meningitidis FAM18 sodium:alanine symporter YP_975532.1 1588503 R 272831 CDS YP_975533.1 121635288 4675828 1590248..1590976 1 NC_008767.1 hypothetical protein 1590976 4675828 NMC1563 Neisseria meningitidis FAM18 hypothetical protein YP_975533.1 1590248 D 272831 CDS YP_975534.1 121635289 4675829 complement(1591035..1591724) 1 NC_008767.1 disulfide bond formation protein 1591724 4675829 NMC1564 Neisseria meningitidis FAM18 disulfide bond formation protein YP_975534.1 1591035 R 272831 CDS YP_975535.1 121635290 4675891 complement(1592281..1592745) 1 NC_008767.1 transcription regulator AsnC 1592745 4675891 NMC1566 Neisseria meningitidis FAM18 transcription regulator AsnC YP_975535.1 1592281 R 272831 CDS YP_975536.1 121635291 4675892 1593070..1594128 1 NC_008767.1 alanine racemase 1594128 alr 4675892 alr Neisseria meningitidis FAM18 alanine racemase YP_975536.1 1593070 D 272831 CDS YP_975537.1 121635292 4676478 complement(1594192..1595547) 1 NC_008767.1 hypothetical protein 1595547 4676478 NMC1568 Neisseria meningitidis FAM18 hypothetical protein YP_975537.1 1594192 R 272831 CDS YP_975538.1 121635293 4675999 complement(1595563..1595835) 1 NC_008767.1 ACT domain-containing protein; hypothetical protein 1595835 4675999 NMC1569 Neisseria meningitidis FAM18 hypothetical protein YP_975538.1 1595563 R 272831 CDS YP_975539.1 121635294 4676000 complement(1595961..1596698) 1 NC_008767.1 hypothetical protein 1596698 4676000 NMC1570 Neisseria meningitidis FAM18 hypothetical protein YP_975539.1 1595961 R 272831 CDS YP_975540.1 121635295 4675857 complement(1596979..1597890) 1 NC_008767.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1597890 4675857 NMC1571 Neisseria meningitidis FAM18 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_975540.1 1596979 R 272831 CDS YP_975541.1 121635296 4675858 1598023..1598616 1 NC_008767.1 hypothetical protein 1598616 4675858 NMC1572 Neisseria meningitidis FAM18 hypothetical protein YP_975541.1 1598023 D 272831 CDS YP_975542.1 121635297 4675881 1598728..1599348 1 NC_008767.1 hypothetical protein 1599348 4675881 NMC1573 Neisseria meningitidis FAM18 hypothetical protein YP_975542.1 1598728 D 272831 CDS YP_975543.1 121635298 4675882 complement(1599279..1599743) 1 NC_008767.1 DNA transport competence protein 1599743 4675882 NMC1574 Neisseria meningitidis FAM18 DNA transport competence protein YP_975543.1 1599279 R 272831 CDS YP_975544.1 121635299 4675965 1605612..1606796 1 NC_008767.1 hypothetical protein 1606796 4675965 NMC1576 Neisseria meningitidis FAM18 hypothetical protein YP_975544.1 1605612 D 272831 CDS YP_975545.1 121635300 4675966 complement(1606863..1609019) 1 NC_008767.1 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 1609019 spoT 4675966 spoT Neisseria meningitidis FAM18 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase YP_975545.1 1606863 R 272831 CDS YP_975546.1 121635301 4675212 complement(1609112..1609318) 1 NC_008767.1 DNA-directed RNA polymerase subunit omega 1609318 rpoZ 4675212 rpoZ Neisseria meningitidis FAM18 DNA-directed RNA polymerase subunit omega YP_975546.1 1609112 R 272831 CDS YP_975547.1 121635302 4675317 complement(1609377..1609994) 1 NC_008767.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1609994 gmk 4675317 gmk Neisseria meningitidis FAM18 guanylate kinase YP_975547.1 1609377 R 272831 CDS YP_975548.1 121635303 4676526 1610122..1610721 1 NC_008767.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1610721 apt 4676526 apt Neisseria meningitidis FAM18 adenine phosphoribosyltransferase YP_975548.1 1610122 D 272831 CDS YP_975549.1 121635304 4676423 complement(1610767..1611555) 1 NC_008767.1 hypothetical protein 1611555 4676423 NMC1581 Neisseria meningitidis FAM18 hypothetical protein YP_975549.1 1610767 R 272831 CDS YP_975550.1 121635305 4675908 1611880..1613235 1 NC_008767.1 protease 1613235 4675908 NMC1582 Neisseria meningitidis FAM18 protease YP_975550.1 1611880 D 272831 CDS YP_975551.1 121635306 4675909 1613369..1613845 1 NC_008767.1 hypothetical protein 1613845 4675909 NMC1583 Neisseria meningitidis FAM18 hypothetical protein YP_975551.1 1613369 D 272831 CDS YP_975552.1 121635307 4675918 complement(1614450..1614836) 1 NC_008767.1 hypothetical protein 1614836 4675918 NMC1584 Neisseria meningitidis FAM18 hypothetical protein YP_975552.1 1614450 R 272831 CDS YP_975553.1 121635308 4675919 complement(1614833..1615078) 1 NC_008767.1 hypothetical protein 1615078 4675919 NMC1585 Neisseria meningitidis FAM18 hypothetical protein YP_975553.1 1614833 R 272831 CDS YP_975554.1 121635309 4675914 complement(join(1615450..1616667,1616666..1617829)) 1 NC_008767.1 hypothetical protein 1617829 hmbR 4675914 hmbR Neisseria meningitidis FAM18 hypothetical protein YP_975554.1 1615450 R 272831 CDS YP_975555.1 121635310 4676343 complement(1618004..1618696) 1 NC_008767.1 heme utilisation protein 1618696 hemO 4676343 hemO Neisseria meningitidis FAM18 heme utilisation protein YP_975555.1 1618004 R 272831 CDS YP_975556.1 121635311 4675851 1619127..1620431 1 NC_008767.1 hypothetical protein 1620431 4675851 NMC1588 Neisseria meningitidis FAM18 hypothetical protein YP_975556.1 1619127 D 272831 CDS YP_975557.1 121635312 4675915 1620424..1622064 1 NC_008767.1 hypothetical protein 1622064 4675915 NMC1589 Neisseria meningitidis FAM18 hypothetical protein YP_975557.1 1620424 D 272831 CDS YP_975558.1 121635313 4675722 1622064..1622582 1 NC_008767.1 lipoprotein 1622582 4675722 NMC1590 Neisseria meningitidis FAM18 lipoprotein YP_975558.1 1622064 D 272831 CDS YP_975559.1 121635314 4675723 1622586..1623137 1 NC_008767.1 DNA-3-methyladenine glycosylase I 1623137 tag 4675723 tag Neisseria meningitidis FAM18 DNA-3-methyladenine glycosylase I YP_975559.1 1622586 D 272831 CDS YP_975560.1 121635315 4674942 1623145..1623768 1 NC_008767.1 lipase 1623768 4674942 NMC1592 Neisseria meningitidis FAM18 lipase YP_975560.1 1623145 D 272831 CDS YP_975561.1 121635316 4675843 1623990..1624298 1 NC_008767.1 hypothetical protein 1624298 4675843 NMC1593 Neisseria meningitidis FAM18 hypothetical protein YP_975561.1 1623990 D 272831 CDS YP_975562.1 121635317 4675844 1624329..1627181 1 NC_008767.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 1627181 gcvP 4675844 gcvP Neisseria meningitidis FAM18 glycine dehydrogenase YP_975562.1 1624329 D 272831 CDS YP_975563.1 121635318 4676634 complement(1627646..1628485) 1 NC_008767.1 cytochrome 1628485 4676634 NMC1595 Neisseria meningitidis FAM18 cytochrome YP_975563.1 1627646 R 272831 CDS YP_975564.1 121635319 4675895 complement(1628910..1630103) 1 NC_008767.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1630103 tyrB 4675895 tyrB Neisseria meningitidis FAM18 aromatic amino acid aminotransferase YP_975564.1 1628910 R 272831 CDS YP_975565.1 121635320 4676482 complement(1630109..1631212) 1 NC_008767.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 1631212 trmA 4676482 trmA Neisseria meningitidis FAM18 tRNA (uracil-5-)-methyltransferase YP_975565.1 1630109 R 272831 CDS YP_975566.1 121635321 4675192 1631355..1632455 1 NC_008767.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1632455 aroC 4675192 aroC Neisseria meningitidis FAM18 chorismate synthase YP_975566.1 1631355 D 272831 CDS YP_975567.1 121635322 4675501 1632546..1632971 1 NC_008767.1 hypothetical protein 1632971 4675501 NMC1599 Neisseria meningitidis FAM18 hypothetical protein YP_975567.1 1632546 D 272831 CDS YP_975568.1 121635323 4675896 complement(1633045..1635030) 1 NC_008767.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1635030 parE 4675896 parE Neisseria meningitidis FAM18 DNA topoisomerase IV subunit B YP_975568.1 1633045 R 272831 CDS YP_975569.1 121635324 4676175 complement(1635097..1635621) 1 NC_008767.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1635621 4676175 NMC1601 Neisseria meningitidis FAM18 dinucleoside polyphosphate hydrolase YP_975569.1 1635097 R 272831 CDS YP_975570.1 121635325 4675860 1635786..1637081 1 NC_008767.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1637081 serS 4675860 serS Neisseria meningitidis FAM18 seryl-tRNA synthetase YP_975570.1 1635786 D 272831 CDS YP_975571.1 121635326 4675082 complement(1637159..1638160) 1 NC_008767.1 D-lactate dehydrogenase 1638160 ldhA 4675082 ldhA Neisseria meningitidis FAM18 D-lactate dehydrogenase YP_975571.1 1637159 R 272831 CDS YP_975572.1 121635327 4676407 complement(1638282..1639358) 1 NC_008767.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1639358 prfA 4676407 prfA Neisseria meningitidis FAM18 peptide chain release factor 1 YP_975572.1 1638282 R 272831 CDS YP_975573.1 121635328 4676066 complement(1639448..1640272) 1 NC_008767.1 hypothetical protein 1640272 4676066 NMC1605 Neisseria meningitidis FAM18 hypothetical protein YP_975573.1 1639448 R 272831 CDS YP_975574.1 121635329 4675861 complement(1640221..1641213) 1 NC_008767.1 L-asparaginase 1641213 ans 4675861 ans Neisseria meningitidis FAM18 L-asparaginase YP_975574.1 1640221 R 272831 CDS YP_975575.1 121635330 4676466 complement(1641280..1641963) 1 NC_008767.1 DedA family integral membrane protein 1641963 4676466 NMC1607 Neisseria meningitidis FAM18 DedA family integral membrane protein YP_975575.1 1641280 R 272831 CDS YP_975576.1 121635331 4675873 complement(1642152..1643486) 1 NC_008767.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1643486 glmM 4675873 glmM Neisseria meningitidis FAM18 phosphoglucosamine mutase YP_975576.1 1642152 R 272831 CDS YP_975577.1 121635332 4675874 complement(1643616..1644467) 1 NC_008767.1 dihydropteroate synthase 1644467 dhpS 4675874 dhpS Neisseria meningitidis FAM18 dihydropteroate synthase YP_975577.1 1643616 R 272831 CDS YP_975578.1 121635333 4675975 1644634..1646856 1 NC_008767.1 hypothetical protein 1646856 4675975 NMC1610 Neisseria meningitidis FAM18 hypothetical protein YP_975578.1 1644634 D 272831 CDS YP_975579.1 121635334 4675862 complement(1646921..1648405) 1 NC_008767.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1648405 4675862 NMC1611 Neisseria meningitidis FAM18 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_975579.1 1646921 R 272831 CDS YP_975580.1 121635335 4675863 complement(1648419..1648934) 1 NC_008767.1 hypothetical protein 1648934 4675863 NMC1613 Neisseria meningitidis FAM18 hypothetical protein YP_975580.1 1648419 R 272831 CDS YP_975581.1 121635336 4675864 complement(1648941..1649375) 1 NC_008767.1 hypothetical protein 1649375 4675864 NMC1614 Neisseria meningitidis FAM18 hypothetical protein YP_975581.1 1648941 R 272831 CDS YP_975582.1 121635337 4675865 complement(1649673..1650107) 1 NC_008767.1 hypothetical protein 1650107 4675865 NMC1615 Neisseria meningitidis FAM18 hypothetical protein YP_975582.1 1649673 R 272831 CDS YP_975583.1 121635338 4675877 1650282..1650893 1 NC_008767.1 insertion element IS1016 transposase 1650893 4675877 NMC1616 Neisseria meningitidis FAM18 insertion element IS1016 transposase YP_975583.1 1650282 D 272831 CDS YP_975584.1 121635339 4675878 join(1650838..1651560,1651564..1651974) 1 NC_008767.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1651974 fabF2 4675878 fabF2 Neisseria meningitidis FAM18 3-oxoacyl-ACP synthase YP_975584.1 1650838 D 272831 CDS YP_975585.1 121635340 4675840 1652172..1652936 1 NC_008767.1 beta-1,4-glucosyltransferase 1652936 lgtF 4675840 lgtF Neisseria meningitidis FAM18 beta-1,4-glucosyltransferase YP_975585.1 1652172 D 272831 CDS YP_975586.1 121635341 4676380 1652937..1654001 1 NC_008767.1 alpha 1,2 N-acetylglucosamine transferase 1654001 rfaK 4676380 rfaK Neisseria meningitidis FAM18 alpha 1,2 N-acetylglucosamine transferase YP_975586.1 1652937 D 272831 CDS YP_975587.1 121635342 4675559 1654040..1654210 1 NC_008767.1 hypothetical protein 1654210 4675559 NMC1621 Neisseria meningitidis FAM18 hypothetical protein YP_975587.1 1654040 D 272831 CDS YP_975588.1 121635343 4675868 1654388..1655725 1 NC_008767.1 integral membrane ion transporter 1655725 4675868 NMC1622 Neisseria meningitidis FAM18 integral membrane ion transporter YP_975588.1 1654388 D 272831 CDS YP_975589.1 121635344 4675869 complement(join(1655897..1656298,1656297..1656557)) 1 NC_008767.1 hypothetical protein 1656557 4675869 NMC1623 Neisseria meningitidis FAM18 hypothetical protein YP_975589.1 1655897 R 272831 CDS YP_975590.1 121635345 4675170 complement(1656566..1657360) 1 NC_008767.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1657360 thyA 4675170 thyA Neisseria meningitidis FAM18 thymidylate synthase YP_975590.1 1656566 R 272831 CDS YP_975591.1 121635346 4675196 1657744..1659078 1 NC_008767.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1659078 gdhA 4675196 gdhA Neisseria meningitidis FAM18 glutamate dehydrogenase YP_975591.1 1657744 D 272831 CDS YP_975592.1 121635347 4676618 1659226..1659594 1 NC_008767.1 LOW G+C REGION; hypothetical protein 1659594 4676618 NMC1626 Neisseria meningitidis FAM18 hypothetical protein YP_975592.1 1659226 D 272831 CDS YP_975593.1 121635348 4675277 complement(1660081..1660863) 1 NC_008767.1 GntR family transcriptional regulator 1660863 4675277 NMC1629 Neisseria meningitidis FAM18 GntR family transcriptional regulator YP_975593.1 1660081 R 272831 CDS YP_975594.1 121635349 4675278 1661395..1661694 1 NC_008767.1 hypothetical protein 1661694 4675278 NMC1630 Neisseria meningitidis FAM18 hypothetical protein YP_975594.1 1661395 D 272831 CDS YP_975595.1 121635350 4676611 complement(1662062..1663513) 1 NC_008767.1 outer membrane lipoprotein 1663513 mtrE 4676611 mtrE Neisseria meningitidis FAM18 outer membrane lipoprotein YP_975595.1 1662062 R 272831 CDS YP_975596.1 121635351 4675937 complement(1663520..1666723) 1 NC_008767.1 drug efflux protein 1666723 mtrD 4675937 mtrD Neisseria meningitidis FAM18 drug efflux protein YP_975596.1 1663520 R 272831 CDS YP_975597.1 121635352 4676291 complement(1666735..1667973) 1 NC_008767.1 membrane fusion protein 1667973 mtrC 4676291 mtrC Neisseria meningitidis FAM18 membrane fusion protein YP_975597.1 1666735 R 272831 CDS YP_975598.1 121635353 4676290 1668381..1669013 1 NC_008767.1 transcriptional regulator 1669013 mtrR 4676290 mtrR Neisseria meningitidis FAM18 transcriptional regulator YP_975598.1 1668381 D 272831 CDS YP_975599.1 121635354 4675938 complement(1669292..1669549) 1 NC_008767.1 hypothetical protein 1669549 4675938 NMC1636 Neisseria meningitidis FAM18 hypothetical protein YP_975599.1 1669292 R 272831 CDS YP_975600.1 121635355 4676612 1669838..1671406 1 NC_008767.1 hypothetical protein 1671406 4676612 NMC1637 Neisseria meningitidis FAM18 hypothetical protein YP_975600.1 1669838 D 272831 CDS YP_975601.1 121635356 4676284 complement(1671476..1674685) 1 NC_008767.1 exodeoxyribonuclease V 1674685 recC 4676284 recC Neisseria meningitidis FAM18 exodeoxyribonuclease V YP_975601.1 1671476 R 272831 CDS YP_975602.1 121635357 4675754 complement(1674786..1676195) 1 NC_008767.1 hypothetical protein 1676195 4675754 NMC1639 Neisseria meningitidis FAM18 hypothetical protein YP_975602.1 1674786 R 272831 CDS YP_975603.1 121635358 4676471 complement(1677927..1678538) 1 NC_008767.1 CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 1678538 4676471 NMC1643 Neisseria meningitidis FAM18 cbb3-type cytochrome c oxidase subunit II YP_975603.1 1677927 R 272831 CDS YP_975604.1 121635359 4676472 complement(1678565..1680010) 1 NC_008767.1 CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 1680010 4676472 NMC1645 Neisseria meningitidis FAM18 cbb3-type cytochrome c oxidase subunit I YP_975604.1 1678565 R 272831 CDS YP_975605.1 121635360 4676679 1680316..1682073 1 NC_008767.1 hypothetical protein 1682073 4676679 NMC1646 Neisseria meningitidis FAM18 hypothetical protein YP_975605.1 1680316 D 272831 CDS YP_975606.1 121635361 4676680 1682099..1682566 1 NC_008767.1 hypothetical protein 1682566 4676680 NMC1647 Neisseria meningitidis FAM18 hypothetical protein YP_975606.1 1682099 D 272831 CDS YP_975607.1 121635362 4676643 complement(1683253..1683687) 1 NC_008767.1 biopolymer transport protein 1683687 exbD 4676643 exbD Neisseria meningitidis FAM18 biopolymer transport protein YP_975607.1 1683253 R 272831 CDS YP_975608.1 121635363 4675875 complement(1683690..1684352) 1 NC_008767.1 biopolymer transport protein 1684352 exbB 4675875 exbB Neisseria meningitidis FAM18 biopolymer transport protein YP_975608.1 1683690 R 272831 CDS YP_975609.1 121635364 4675898 complement(1684418..1685254) 1 NC_008767.1 TonB protein 1685254 tonB 4675898 tonB Neisseria meningitidis FAM18 TonB protein YP_975609.1 1684418 R 272831 CDS YP_975610.1 121635365 4674851 1685509..1686147 1 NC_008767.1 hypothetical protein 1686147 4674851 NMC1651 Neisseria meningitidis FAM18 hypothetical protein YP_975610.1 1685509 D 272831 CDS YP_975611.1 121635366 4676644 complement(1686599..1687399) 1 NC_008767.1 hypothetical protein 1687399 4676644 NMC1652 Neisseria meningitidis FAM18 hypothetical protein YP_975611.1 1686599 R 272831 CDS YP_975612.1 121635367 4676651 complement(1687535..1688056) 1 NC_008767.1 hypothetical protein 1688056 4676651 NMC1653 Neisseria meningitidis FAM18 hypothetical protein YP_975612.1 1687535 R 272831 CDS YP_975613.1 121635368 4676652 complement(1688378..1689022) 1 NC_008767.1 cofactor involved in the reduction of disulfides; glutaredoxin 1689022 grxB 4676652 grxB Neisseria meningitidis FAM18 glutaredoxin YP_975613.1 1688378 R 272831 CDS YP_975614.1 121635369 4676528 1689347..1691560 1 NC_008767.1 GTP pyrophosphokinase 1691560 relA 4676528 relA Neisseria meningitidis FAM18 GTP pyrophosphokinase YP_975614.1 1689347 D 272831 CDS YP_975615.1 121635370 4676659 complement(1692854..1694257) 1 NC_008767.1 periplasmic type I secretion system protein 1694257 natC 4676659 natC Neisseria meningitidis FAM18 periplasmic type I secretion system protein YP_975615.1 1692854 R 272831 CDS YP_975616.1 121635371 4676237 complement(1694326..1695753) 1 NC_008767.1 periplasmic type I secretion system protein 1695753 4676237 NMC1658 Neisseria meningitidis FAM18 periplasmic type I secretion system protein YP_975616.1 1694326 R 272831 CDS YP_975617.1 121635372 4676660 1696339..1696845 1 NC_008767.1 hypothetical protein 1696845 4676660 NMC1660 Neisseria meningitidis FAM18 hypothetical protein YP_975617.1 1696339 D 272831 CDS YP_975618.1 121635373 4676583 1697238..1698272 1 NC_008767.1 hypothetical protein 1698272 4676583 NMC1661 Neisseria meningitidis FAM18 hypothetical protein YP_975618.1 1697238 D 272831 CDS YP_975619.1 121635374 4676584 1698263..1698607 1 NC_008767.1 hypothetical protein 1698607 4676584 NMC1662 Neisseria meningitidis FAM18 hypothetical protein YP_975619.1 1698263 D 272831 CDS YP_975620.1 121635375 4676396 1698612..1698809 1 NC_008767.1 hypothetical protein 1698809 4676396 NMC1663 Neisseria meningitidis FAM18 hypothetical protein YP_975620.1 1698612 D 272831 CDS YP_975621.1 121635376 4676397 1698817..1699101 1 NC_008767.1 hypothetical protein 1699101 4676397 NMC1664 Neisseria meningitidis FAM18 hypothetical protein YP_975621.1 1698817 D 272831 CDS YP_975622.1 121635377 4676645 1699108..1699386 1 NC_008767.1 hypothetical protein 1699386 4676645 NMC1665 Neisseria meningitidis FAM18 hypothetical protein YP_975622.1 1699108 D 272831 CDS YP_975623.1 121635378 4676646 1699544..1699831 1 NC_008767.1 hypothetical protein 1699831 4676646 NMC1667 Neisseria meningitidis FAM18 hypothetical protein YP_975623.1 1699544 D 272831 CDS YP_975624.1 121635379 4676624 1699812..1700210 1 NC_008767.1 cell-surface protein 1700210 4676624 NMC1668 Neisseria meningitidis FAM18 cell-surface protein YP_975624.1 1699812 D 272831 CDS YP_975625.1 121635380 4676625 complement(1700877..1701236) 1 NC_008767.1 hypothetical protein 1701236 4676625 NMC1669 Neisseria meningitidis FAM18 hypothetical protein YP_975625.1 1700877 R 272831 CDS YP_975626.1 121635381 4676641 complement(1701259..1701903) 1 NC_008767.1 hypothetical protein 1701903 4676641 NMC1670 Neisseria meningitidis FAM18 hypothetical protein YP_975626.1 1701259 R 272831 CDS YP_975627.1 121635382 4676642 complement(1701905..1702441) 1 NC_008767.1 hypothetical protein 1702441 4676642 NMC1671 Neisseria meningitidis FAM18 hypothetical protein YP_975627.1 1701905 R 272831 CDS YP_975628.1 121635383 4676594 complement(1702453..1703550) 1 NC_008767.1 hypothetical protein 1703550 4676594 NMC1672 Neisseria meningitidis FAM18 hypothetical protein YP_975628.1 1702453 R 272831 CDS YP_975629.1 121635384 4676595 complement(1703553..1704965) 1 NC_008767.1 hypothetical protein 1704965 4676595 NMC1673 Neisseria meningitidis FAM18 hypothetical protein YP_975629.1 1703553 R 272831 CDS YP_975630.1 121635385 4676557 complement(1705209..1706003) 1 NC_008767.1 hypothetical protein 1706003 4676557 NMC1674 Neisseria meningitidis FAM18 hypothetical protein YP_975630.1 1705209 R 272831 CDS YP_975631.1 121635386 4676558 complement(1705979..1706626) 1 NC_008767.1 hypothetical protein 1706626 4676558 NMC1675 Neisseria meningitidis FAM18 hypothetical protein YP_975631.1 1705979 R 272831 CDS YP_975632.1 121635387 4676591 complement(1706636..1707778) 1 NC_008767.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1707778 bioF 4676591 bioF Neisseria meningitidis FAM18 8-amino-7-oxononanoate synthase YP_975632.1 1706636 R 272831 CDS YP_975633.1 121635388 4676555 1708001..1709077 1 NC_008767.1 hypothetical protein 1709077 4676555 NMC1677 Neisseria meningitidis FAM18 hypothetical protein YP_975633.1 1708001 D 272831 CDS YP_975634.1 121635389 4676592 complement(1709284..1710750) 1 NC_008767.1 integral membrane transport protein 1710750 4676592 NMC1679 Neisseria meningitidis FAM18 integral membrane transport protein YP_975634.1 1709284 R 272831 CDS YP_975635.1 121635390 4676579 complement(1710948..1711871) 1 NC_008767.1 catalyzes the formation of putrescine from agmatine; agmatinase 1711871 speB 4676579 speB Neisseria meningitidis FAM18 agmatinase YP_975635.1 1710948 R 272831 CDS YP_975636.1 121635391 4675211 complement(1711970..1713862) 1 NC_008767.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 1713862 speA 4675211 speA Neisseria meningitidis FAM18 arginine decarboxylase YP_975636.1 1711970 R 272831 CDS YP_975637.1 121635392 4675026 complement(1714029..1714313) 1 NC_008767.1 hypothetical protein 1714313 4675026 NMC1683 Neisseria meningitidis FAM18 hypothetical protein YP_975637.1 1714029 R 272831 CDS YP_975638.1 121635393 4676580 complement(1714464..1716272) 1 NC_008767.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1716272 aspS 4676580 aspS Neisseria meningitidis FAM18 aspartyl-tRNA synthetase YP_975638.1 1714464 R 272831 CDS YP_975639.1 121635394 4675644 complement(1716330..1717067) 1 NC_008767.1 hypothetical protein 1717067 4675644 NMC1686 Neisseria meningitidis FAM18 hypothetical protein YP_975639.1 1716330 R 272831 CDS YP_975640.1 121635395 4676562 complement(1718482..1718745) 1 NC_008767.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1718745 rpsT 4676562 rpsT Neisseria meningitidis FAM18 30S ribosomal protein S20 YP_975640.1 1718482 R 272831 CDS YP_975641.1 121635396 4675129 1719048..1720190 1 NC_008767.1 polyamine permease substrate-binding protein 1720190 4675129 NMC1689 Neisseria meningitidis FAM18 polyamine permease substrate-binding protein YP_975641.1 1719048 D 272831 CDS YP_975642.1 121635397 4676563 complement(1721463..1724189) 1 NC_008767.1 transferrin-binding protein A 1724189 tbpA 4676563 tbpA Neisseria meningitidis FAM18 transferrin-binding protein A YP_975642.1 1721463 R 272831 CDS YP_975643.1 121635398 4675205 complement(1724276..1726075) 1 NC_008767.1 transferrin-binding protein B 1726075 tbpB 4675205 tbpB Neisseria meningitidis FAM18 transferrin-binding protein B YP_975643.1 1724276 R 272831 CDS YP_975644.1 121635399 4675206 complement(1727770..1728582) 1 NC_008767.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1728582 glr 4675206 glr Neisseria meningitidis FAM18 glutamate racemase YP_975644.1 1727770 R 272831 CDS YP_975645.1 121635400 4676599 1728772..1729233 1 NC_008767.1 hypothetical protein 1729233 4676599 NMC1693 Neisseria meningitidis FAM18 hypothetical protein YP_975645.1 1728772 D 272831 CDS YP_975646.1 121635401 4676564 1729230..1730480 1 NC_008767.1 N-acetylmuramoyl-L-alanine amidase 1730480 amiC 4676564 amiC Neisseria meningitidis FAM18 N-acetylmuramoyl-L-alanine amidase YP_975646.1 1729230 D 272831 CDS YP_975647.1 121635402 4676479 1730544..1731365 1 NC_008767.1 hypothetical protein 1731365 4676479 NMC1695 Neisseria meningitidis FAM18 hypothetical protein YP_975647.1 1730544 D 272831 CDS YP_975648.1 121635403 4676539 complement(1731666..1732808) 1 NC_008767.1 hypothetical protein 1732808 4676539 NMC1697 Neisseria meningitidis FAM18 hypothetical protein YP_975648.1 1731666 R 272831 CDS YP_975649.1 121635404 4676540 complement(1732857..1733279) 1 NC_008767.1 secreted protein 1733279 4676540 NMC1698 Neisseria meningitidis FAM18 secreted protein YP_975649.1 1732857 R 272831 CDS YP_975650.1 121635405 4676543 complement(1733272..1734081) 1 NC_008767.1 MutT-like protein 1734081 4676543 NMC1699 Neisseria meningitidis FAM18 MutT-like protein YP_975650.1 1733272 R 272831 CDS YP_975651.1 121635406 4676544 complement(1734163..1734540) 1 NC_008767.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1734540 acpS 4676544 acpS Neisseria meningitidis FAM18 4'-phosphopantetheinyl transferase YP_975651.1 1734163 R 272831 CDS YP_975652.1 121635407 4675517 complement(1734740..1735507) 1 NC_008767.1 hypothetical protein 1735507 4675517 NMC1701 Neisseria meningitidis FAM18 hypothetical protein YP_975652.1 1734740 R 272831 CDS YP_975653.1 121635408 4676548 complement(join(1735517..1736056,1736228..1736449)) 1 NC_008767.1 hypothetical protein 1736449 4676548 NMC1702 Neisseria meningitidis FAM18 hypothetical protein YP_975653.1 1735517 R 272831 CDS YP_975654.1 121635409 4676549 complement(1736601..1737329) 1 NC_008767.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1737329 pdxJ 4676549 pdxJ Neisseria meningitidis FAM18 pyridoxine 5'-phosphate synthase YP_975654.1 1736601 R 272831 CDS YP_975655.1 121635410 4676157 complement(1737353..1738147) 1 NC_008767.1 DNA repair protein (recombination protein o) 1738147 recO 4676157 recO Neisseria meningitidis FAM18 DNA repair protein (recombination protein o) YP_975655.1 1737353 R 272831 CDS YP_975656.1 121635411 4675740 complement(1738178..1739308) 1 NC_008767.1 chorismate mutase 1739308 pheA 4675740 pheA Neisseria meningitidis FAM18 chorismate mutase YP_975656.1 1738178 R 272831 CDS YP_975657.1 121635412 4676111 complement(1739344..1740723) 1 NC_008767.1 integral membrane efflux protein 1740723 4676111 NMC1706 Neisseria meningitidis FAM18 integral membrane efflux protein YP_975657.1 1739344 R 272831 CDS YP_975658.1 121635413 4676519 complement(1741096..1741980) 1 NC_008767.1 hypothetical protein 1741980 4676519 NMC1708 Neisseria meningitidis FAM18 hypothetical protein YP_975658.1 1741096 R 272831 CDS YP_975659.1 121635414 4676520 1743688..1744896 1 NC_008767.1 hypothetical protein 1744896 4676520 NMC1709 Neisseria meningitidis FAM18 hypothetical protein YP_975659.1 1743688 D 272831 CDS YP_975660.1 121635415 4676533 1744917..1745228 1 NC_008767.1 hypothetical protein 1745228 4676533 NMC1710 Neisseria meningitidis FAM18 hypothetical protein YP_975660.1 1744917 D 272831 CDS YP_975661.1 121635416 4676534 1745232..1745432 1 NC_008767.1 hypothetical protein 1745432 4676534 NMC1711 Neisseria meningitidis FAM18 hypothetical protein YP_975661.1 1745232 D 272831 CDS YP_975662.1 121635417 4676514 1745659..1745889 1 NC_008767.1 hypothetical protein 1745889 4676514 NMC1712 Neisseria meningitidis FAM18 hypothetical protein YP_975662.1 1745659 D 272831 CDS YP_975663.1 121635418 4676515 1745917..1746216 1 NC_008767.1 hypothetical protein 1746216 4676515 NMC1713 Neisseria meningitidis FAM18 hypothetical protein YP_975663.1 1745917 D 272831 CDS YP_975664.1 121635419 4676516 1746233..1746655 1 NC_008767.1 hypothetical protein 1746655 4676516 NMC1714 Neisseria meningitidis FAM18 hypothetical protein YP_975664.1 1746233 D 272831 CDS YP_975665.1 121635420 4676517 1746543..1748162 1 NC_008767.1 TspB protein 1748162 4676517 NMC1715 Neisseria meningitidis FAM18 TspB protein YP_975665.1 1746543 D 272831 CDS YP_975666.1 121635421 4676488 1748465..1748749 1 NC_008767.1 hypothetical protein 1748749 4676488 NMC1716 Neisseria meningitidis FAM18 hypothetical protein YP_975666.1 1748465 D 272831 CDS YP_975667.1 121635422 4676489 1748750..1749937 1 NC_008767.1 hypothetical protein 1749937 4676489 NMC1717 Neisseria meningitidis FAM18 hypothetical protein YP_975667.1 1748750 D 272831 CDS YP_975668.1 121635423 4676492 1750152..1751108 1 NC_008767.1 transposase 1751108 4676492 NMC1718 Neisseria meningitidis FAM18 transposase YP_975668.1 1750152 D 272831 CDS YP_975669.1 121635424 4676493 1751514..1752332 1 NC_008767.1 Opa1800 outer membrane protein 1752332 4676493 NMC1719 Neisseria meningitidis FAM18 Opa1800 outer membrane protein YP_975669.1 1751514 D 272831 CDS YP_975670.1 121635425 4676501 complement(1754168..1754980) 1 NC_008767.1 hypothetical protein 1754980 4676501 NMC1720 Neisseria meningitidis FAM18 hypothetical protein YP_975670.1 1754168 R 272831 CDS YP_975671.1 121635426 4676502 1755065..1755937 1 NC_008767.1 oxidoreductase 1755937 4676502 NMC1721 Neisseria meningitidis FAM18 oxidoreductase YP_975671.1 1755065 D 272831 CDS YP_975672.1 121635427 4676486 complement(1755994..1757196) 1 NC_008767.1 hypothetical protein 1757196 4676486 NMC1722 Neisseria meningitidis FAM18 hypothetical protein YP_975672.1 1755994 R 272831 CDS YP_975673.1 121635428 4676487 complement(1757193..1757561) 1 NC_008767.1 hypothetical protein 1757561 4676487 NMC1724 Neisseria meningitidis FAM18 hypothetical protein YP_975673.1 1757193 R 272831 CDS YP_975674.1 121635429 4676494 1757735..1758178 1 NC_008767.1 hypothetical protein 1758178 4676494 NMC1725 Neisseria meningitidis FAM18 hypothetical protein YP_975674.1 1757735 D 272831 CDS YP_975675.1 121635430 4676495 complement(1758305..1759069) 1 NC_008767.1 hypothetical protein 1759069 4676495 NMC1726 Neisseria meningitidis FAM18 hypothetical protein YP_975675.1 1758305 R 272831 CDS YP_975676.1 121635431 4676469 complement(1759032..1760231) 1 NC_008767.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1760231 ackA2 4676469 ackA2 Neisseria meningitidis FAM18 acetate kinase YP_975676.1 1759032 R 272831 CDS YP_975677.1 121635432 4675428 complement(1760646..1761815) 1 NC_008767.1 hypothetical protein 1761815 4675428 NMC1728 Neisseria meningitidis FAM18 hypothetical protein YP_975677.1 1760646 R 272831 CDS YP_975678.1 121635433 4676470 complement(1762168..1764774) 1 NC_008767.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1764774 acnA 4676470 acnA Neisseria meningitidis FAM18 aconitate hydratase YP_975678.1 1762168 R 272831 CDS YP_975679.1 121635434 4675429 complement(1764877..1766094) 1 NC_008767.1 hypothetical protein 1766094 4675429 NMC1730 Neisseria meningitidis FAM18 hypothetical protein YP_975679.1 1764877 R 272831 CDS YP_975680.1 121635435 4676448 complement(1766108..1766833) 1 NC_008767.1 D-alanyl-d-alanine dipeptidase 1766833 ddpX 4676448 ddpX Neisseria meningitidis FAM18 D-alanyl-d-alanine dipeptidase YP_975680.1 1766108 R 272831 CDS YP_975681.1 121635436 4675930 complement(1766923..1768077) 1 NC_008767.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 1768077 prpC 4675930 prpC Neisseria meningitidis FAM18 methylcitrate synthase YP_975681.1 1766923 R 272831 CDS YP_975682.1 121635437 4676027 complement(1768163..1769041) 1 NC_008767.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 1769041 prpB 4676027 prpB Neisseria meningitidis FAM18 2-methylisocitrate lyase YP_975682.1 1768163 R 272831 CDS YP_975683.1 121635438 4676053 complement(1769664..1770974) 1 NC_008767.1 permease 1770974 4676053 NMC1735 Neisseria meningitidis FAM18 permease YP_975683.1 1769664 R 272831 CDS YP_975684.1 121635439 4676449 complement(1771113..1772291) 1 NC_008767.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1772291 ftsZ 4676449 ftsZ Neisseria meningitidis FAM18 cell division protein FtsZ YP_975684.1 1771113 R 272831 CDS YP_975685.1 121635440 4676635 complement(1772410..1773654) 1 NC_008767.1 cell division protein 1773654 ftsA 4676635 ftsA Neisseria meningitidis FAM18 cell division protein YP_975685.1 1772410 R 272831 CDS YP_975686.1 121635441 4676608 complement(1773740..1774468) 1 NC_008767.1 cell division protein 1774468 ftsQ 4676608 ftsQ Neisseria meningitidis FAM18 cell division protein YP_975686.1 1773740 R 272831 CDS YP_975687.1 121635442 4676650 complement(1774458..1775372) 1 NC_008767.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1775372 ddl 4676650 ddl Neisseria meningitidis FAM18 D-alanine--D-alanine ligase YP_975687.1 1774458 R 272831 CDS YP_975688.2 229270471 4676002 complement(1775485..1776891) 1 NC_008767.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1776891 murC 4676002 murC Neisseria meningitidis FAM18 UDP-N-acetylmuramate--L-alanine ligase YP_975688.2 1775485 R 272831 CDS YP_975689.1 121635444 4676263 complement(1777048..1778115) 1 NC_008767.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1778115 murG 4676263 murG Neisseria meningitidis FAM18 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_975689.1 1777048 R 272831 CDS YP_975690.1 121635445 4676260 complement(1778119..1779426) 1 NC_008767.1 cell division protein 1779426 ftsW 4676260 ftsW Neisseria meningitidis FAM18 cell division protein YP_975690.1 1778119 R 272831 CDS YP_975691.1 121635446 4676664 complement(1779570..1780907) 1 NC_008767.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1780907 murD 4676664 murD Neisseria meningitidis FAM18 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_975691.1 1779570 R 272831 CDS YP_975692.1 121635447 4676264 complement(1780997..1781269) 1 NC_008767.1 hypothetical protein 1781269 4676264 NMC1746 Neisseria meningitidis FAM18 hypothetical protein YP_975692.1 1780997 R 272831 CDS YP_975693.1 121635448 4676446 complement(1781384..1782466) 1 NC_008767.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1782466 mraY 4676446 mraY Neisseria meningitidis FAM18 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_975693.1 1781384 R 272831 CDS YP_975694.1 121635449 4676295 complement(1782713..1782895) 1 NC_008767.1 hypothetical protein 1782895 4676295 NMC1748 Neisseria meningitidis FAM18 hypothetical protein YP_975694.1 1782713 R 272831 CDS YP_975695.1 121635450 4676447 complement(1782892..1784331) 1 NC_008767.1 deleted EC_number 6.3.2.15; UDP-MurNAc-pentapeptide synthetase 1784331 murF 4676447 murF Neisseria meningitidis FAM18 UDP-MurNAc-pentapeptide synthetase YP_975695.1 1782892 R 272831 CDS YP_975696.1 121635451 4676085 complement(1784374..1786020) 1 NC_008767.1 hypothetical protein 1786020 4676085 NMC1750 Neisseria meningitidis FAM18 hypothetical protein YP_975696.1 1784374 R 272831 CDS YP_975697.1 121635452 4676456 complement(1786043..1787521) 1 NC_008767.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1787521 murE 4676456 murE Neisseria meningitidis FAM18 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_975697.1 1786043 R 272831 CDS YP_975698.1 121635453 4676084 complement(1787546..1789291) 1 NC_008767.1 penicillin-binding protein 2 1789291 penA 4676084 penA Neisseria meningitidis FAM18 penicillin-binding protein 2 YP_975698.1 1787546 R 272831 CDS YP_975699.1 121635454 4676105 complement(1789352..1789621) 1 NC_008767.1 small periplasmic protein 1789621 4676105 NMC1754 Neisseria meningitidis FAM18 small periplasmic protein YP_975699.1 1789352 R 272831 CDS YP_975700.1 121635455 4676457 complement(1789612..1790598) 1 NC_008767.1 S-adenosyl-methyltransferase MraW 1790598 mraW 4676457 mraW Neisseria meningitidis FAM18 S-adenosyl-methyltransferase MraW YP_975700.1 1789612 R 272831 CDS YP_975701.1 121635456 4676460 complement(1790595..1791050) 1 NC_008767.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1791050 4676460 NMC1756 Neisseria meningitidis FAM18 cell division protein MraZ YP_975701.1 1790595 R 272831 CDS YP_975702.1 121635457 4676461 1791329..1792546 1 NC_008767.1 hypothetical protein 1792546 4676461 NMC1757 Neisseria meningitidis FAM18 hypothetical protein YP_975702.1 1791329 D 272831 CDS YP_975703.1 121635458 4676401 complement(1793119..1793940) 1 NC_008767.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 1793940 4676401 NMC1759 Neisseria meningitidis FAM18 undecaprenyl pyrophosphate phosphatase YP_975703.1 1793119 R 272831 CDS YP_975704.1 121635459 4676402 complement(1793973..1794617) 1 NC_008767.1 thiol:disulfide interchange protein 1794617 4676402 NMC1760 Neisseria meningitidis FAM18 thiol:disulfide interchange protein YP_975704.1 1793973 R 272831 CDS YP_975705.1 121635460 4676224 complement(1794620..1795471) 1 NC_008767.1 hypothetical protein 1795471 4676224 NMC1762 Neisseria meningitidis FAM18 hypothetical protein YP_975705.1 1794620 R 272831 CDS YP_975706.1 121635461 4676225 complement(1795571..1797067) 1 NC_008767.1 chelatase 1797067 4676225 NMC1763 Neisseria meningitidis FAM18 chelatase YP_975706.1 1795571 R 272831 CDS YP_975707.1 121635462 4676413 complement(1797081..1797434) 1 NC_008767.1 hypothetical protein 1797434 4676413 NMC1764 Neisseria meningitidis FAM18 hypothetical protein YP_975707.1 1797081 R 272831 CDS YP_975708.1 121635463 4676414 1797884..1799410 1 NC_008767.1 sodium/proline symporter 1799410 putP 4676414 putP Neisseria meningitidis FAM18 sodium/proline symporter YP_975708.1 1797884 D 272831 CDS YP_975709.1 121635464 4675782 join(1799442..1799630,1799629..1803264) 1 NC_008767.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1803264 putA 4675782 putA Neisseria meningitidis FAM18 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_975709.1 1799442 D 272831 CDS YP_975710.1 121635465 4676030 complement(1804266..1804847) 1 NC_008767.1 transposase 1804847 4676030 NMC1767 Neisseria meningitidis FAM18 transposase YP_975710.1 1804266 R 272831 CDS YP_975711.1 121635466 4676358 complement(1805789..1806559) 1 NC_008767.1 exodeoxyribonuclease III 1806559 xthA 4676358 xthA Neisseria meningitidis FAM18 exodeoxyribonuclease III YP_975711.1 1805789 R 272831 CDS YP_975712.1 121635467 4676667 complement(1806619..1806900) 1 NC_008767.1 ArsR family transcriptional regulator 1806900 4676667 NMC1769 Neisseria meningitidis FAM18 ArsR family transcriptional regulator YP_975712.1 1806619 R 272831 CDS YP_975713.1 121635468 4676359 complement(1807368..1808249) 1 NC_008767.1 nicotinate-nucleotide pyrophosphorylase 1808249 nadC 4676359 nadC Neisseria meningitidis FAM18 nicotinate-nucleotide pyrophosphorylase YP_975713.1 1807368 R 272831 CDS YP_975714.1 121635469 4676252 complement(1808324..1809262) 1 NC_008767.1 cytoplasmic membrane protein 1809262 4676252 NMC1771 Neisseria meningitidis FAM18 cytoplasmic membrane protein YP_975714.1 1808324 R 272831 CDS YP_975715.1 121635470 4676346 1809569..1810681 1 NC_008767.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1810681 nadA 4676346 nadA Neisseria meningitidis FAM18 quinolinate synthetase YP_975715.1 1809569 D 272831 CDS YP_975716.1 121635471 4676254 1810887..1812395 1 NC_008767.1 L-aspartate oxidase 1812395 nadB 4676254 nadB Neisseria meningitidis FAM18 L-aspartate oxidase YP_975716.1 1810887 D 272831 CDS YP_975717.1 121635472 4676347 1813627..1814634 1 NC_008767.1 transposase for IS1106A3 1814634 4676347 NMC1775 Neisseria meningitidis FAM18 transposase for IS1106A3 YP_975717.1 1813627 D 272831 CDS YP_975718.1 121635473 4676354 complement(1814844..1815509) 1 NC_008767.1 beta-phosphoglucomutase 1815509 pgm2 4676354 pgm2 Neisseria meningitidis FAM18 beta-phosphoglucomutase YP_975718.1 1814844 R 272831 CDS YP_975719.1 121635474 4676132 complement(1815522..1817780) 1 NC_008767.1 maltose phosphorylase 1817780 mapA 4676132 mapA Neisseria meningitidis FAM18 maltose phosphorylase YP_975719.1 1815522 R 272831 CDS YP_975720.1 121635475 4676325 complement(1818014..1819051) 1 NC_008767.1 aldose 1-epimerase 1819051 galM 4676325 galM Neisseria meningitidis FAM18 aldose 1-epimerase YP_975720.1 1818014 R 272831 CDS YP_975721.1 121635476 4676656 complement(1819055..1820410) 1 NC_008767.1 integral membrane transport protein 1820410 4676656 NMC1779 Neisseria meningitidis FAM18 integral membrane transport protein YP_975721.1 1819055 R 272831 CDS YP_975722.1 121635477 4676355 1820798..1822474 1 NC_008767.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1822474 4676355 NMC1780 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975722.1 1820798 D 272831 CDS YP_975723.1 121635478 4676352 complement(1822534..1823019) 1 NC_008767.1 phosphatidylglycerophosphatase A 1823019 pgpA 4676352 pgpA Neisseria meningitidis FAM18 phosphatidylglycerophosphatase A YP_975723.1 1822534 R 272831 CDS YP_975724.1 121635479 4676040 complement(1823012..1823968) 1 NC_008767.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 1823968 thiL 4676040 thiL Neisseria meningitidis FAM18 thiamine monophosphate kinase YP_975724.1 1823012 R 272831 CDS YP_975725.1 121635480 4675200 complement(1824789..1825517) 1 NC_008767.1 outer membrane protein class 4 1825517 rmpM 4675200 rmpM Neisseria meningitidis FAM18 outer membrane protein class 4 YP_975725.1 1824789 R 272831 CDS YP_975726.1 121635481 4675578 1825881..1826831 1 NC_008767.1 transcriptional regulator CysB-like protein 1826831 4675578 NMC1784 Neisseria meningitidis FAM18 transcriptional regulator CysB-like protein YP_975726.1 1825881 D 272831 CDS YP_975727.1 121635482 4676353 complement(1826944..1827678) 1 NC_008767.1 anaerobic transcriptional regulatory protein 1827678 4676353 NMC1785 Neisseria meningitidis FAM18 anaerobic transcriptional regulatory protein YP_975727.1 1826944 R 272831 CDS YP_975728.1 121635483 4675664 1827883..1829304 1 NC_008767.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1829304 hemN 4675664 hemN Neisseria meningitidis FAM18 coproporphyrinogen III oxidase YP_975728.1 1827883 D 272831 CDS YP_975729.1 121635484 4676498 complement(1829657..1831231) 1 NC_008767.1 phosphate permease 1831231 4676498 NMC1787 Neisseria meningitidis FAM18 phosphate permease YP_975729.1 1829657 R 272831 CDS YP_975730.1 121635485 4675665 1831553..1832656 1 NC_008767.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1832656 anmK 4675665 anmK Neisseria meningitidis FAM18 anhydro-N-acetylmuramic acid kinase YP_975730.1 1831553 D 272831 CDS YP_975731.1 121635486 4676322 1832775..1833716 1 NC_008767.1 adhesin 1833716 mafA2 4676322 mafA2 Neisseria meningitidis FAM18 adhesin YP_975731.1 1832775 D 272831 CDS YP_975732.1 121635487 4676327 1833720..1835483 1 NC_008767.1 adhesin 1835483 4676327 NMC1790 Neisseria meningitidis FAM18 adhesin YP_975732.1 1833720 D 272831 CDS YP_975733.1 121635488 4676323 1835486..1835809 1 NC_008767.1 LOW G+C REGION; hypothetical protein 1835809 4676323 NMC1791 Neisseria meningitidis FAM18 hypothetical protein YP_975733.1 1835486 D 272831 CDS YP_975734.1 121635489 4676320 1835862..1836095 1 NC_008767.1 LOW G+C REGION; hypothetical protein 1836095 4676320 NMC1792 Neisseria meningitidis FAM18 hypothetical protein YP_975734.1 1835862 D 272831 CDS YP_975735.1 121635490 4676321 1836222..1836764 1 NC_008767.1 LOW G+C REGION; hypothetical protein 1836764 4676321 NMC1793 Neisseria meningitidis FAM18 hypothetical protein YP_975735.1 1836222 D 272831 CDS YP_975736.1 121635491 4676341 1837582..1837980 1 NC_008767.1 hypothetical protein 1837980 4676341 NMC1795 Neisseria meningitidis FAM18 hypothetical protein YP_975736.1 1837582 D 272831 CDS YP_975737.1 121635492 4676303 1838011..1838388 1 NC_008767.1 hypothetical protein 1838388 4676303 NMC1796 Neisseria meningitidis FAM18 hypothetical protein YP_975737.1 1838011 D 272831 CDS YP_975738.1 121635493 4676304 1838520..1838984 1 NC_008767.1 hypothetical protein 1838984 4676304 NMC1797 Neisseria meningitidis FAM18 hypothetical protein YP_975738.1 1838520 D 272831 CDS YP_975739.1 121635494 4676281 1838993..1839265 1 NC_008767.1 hypothetical protein 1839265 4676281 NMC1798 Neisseria meningitidis FAM18 hypothetical protein YP_975739.1 1838993 D 272831 CDS YP_975740.1 121635495 4676282 1839432..1839662 1 NC_008767.1 hypothetical protein 1839662 4676282 NMC1799 Neisseria meningitidis FAM18 hypothetical protein YP_975740.1 1839432 D 272831 CDS YP_975741.1 121635496 4676279 1839813..1840442 1 NC_008767.1 hypothetical protein 1840442 4676279 NMC1800 Neisseria meningitidis FAM18 hypothetical protein YP_975741.1 1839813 D 272831 CDS YP_975742.1 121635497 4676280 1840393..1840878 1 NC_008767.1 hypothetical protein 1840878 4676280 NMC1801 Neisseria meningitidis FAM18 hypothetical protein YP_975742.1 1840393 D 272831 CDS YP_975743.1 121635498 4676297 1841099..1841458 1 NC_008767.1 LOW G+C REGION; lipoprotein 1841458 4676297 NMC1802 Neisseria meningitidis FAM18 lipoprotein YP_975743.1 1841099 D 272831 CDS YP_975744.1 121635499 4676298 1841470..1841805 1 NC_008767.1 hypothetical protein 1841805 4676298 NMC1803 Neisseria meningitidis FAM18 hypothetical protein YP_975744.1 1841470 D 272831 CDS YP_975745.1 121635500 4676311 1842109..1843233 1 NC_008767.1 hypothetical protein 1843233 4676311 NMC1804 Neisseria meningitidis FAM18 hypothetical protein YP_975745.1 1842109 D 272831 CDS YP_975746.1 121635501 4676312 complement(1843320..1843595) 1 NC_008767.1 hypothetical protein 1843595 4676312 NMC1805 Neisseria meningitidis FAM18 hypothetical protein YP_975746.1 1843320 R 272831 CDS YP_975747.1 121635502 4676248 complement(1843612..1844379) 1 NC_008767.1 hypothetical protein 1844379 4676248 NMC1806 Neisseria meningitidis FAM18 hypothetical protein YP_975747.1 1843612 R 272831 CDS YP_975748.1 121635503 4676249 complement(1844804..1845079) 1 NC_008767.1 hypothetical protein 1845079 4676249 NMC1807 Neisseria meningitidis FAM18 hypothetical protein YP_975748.1 1844804 R 272831 CDS YP_975749.1 121635504 4676276 complement(1845076..1846359) 1 NC_008767.1 integral membrane signal transducer protein 1846359 4676276 NMC1808 Neisseria meningitidis FAM18 integral membrane signal transducer protein YP_975749.1 1845076 R 272831 CDS YP_975750.1 121635505 4676277 complement(1846513..1847931) 1 NC_008767.1 glutamine synthetase 1847931 glnA 4676277 glnA Neisseria meningitidis FAM18 glutamine synthetase YP_975750.1 1846513 R 272831 CDS YP_975751.1 121635506 4676581 1848753..1849562 1 NC_008767.1 shikimate dehydrogenase 1849562 aroE 4676581 aroE Neisseria meningitidis FAM18 shikimate dehydrogenase YP_975751.1 1848753 D 272831 CDS YP_975752.1 121635507 4675566 1849564..1850265 1 NC_008767.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 1850265 mtgA 4675566 mtgA Neisseria meningitidis FAM18 monofunctional biosynthetic peptidoglycan transglycosylase YP_975752.1 1849564 D 272831 CDS YP_975753.1 121635508 4676296 complement(1850734..1851498) 1 NC_008767.1 ABC transporter ATP-binding protein 1851498 4676296 NMC1812 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975753.1 1850734 R 272831 CDS YP_975754.1 121635509 4676241 complement(1851542..1852072) 1 NC_008767.1 hypothetical protein 1852072 4676241 NMC1813 Neisseria meningitidis FAM18 hypothetical protein YP_975754.1 1851542 R 272831 CDS YP_975755.1 121635510 4676242 complement(1852053..1852634) 1 NC_008767.1 hypothetical protein 1852634 4676242 NMC1814 Neisseria meningitidis FAM18 hypothetical protein YP_975755.1 1852053 R 272831 CDS YP_975756.1 121635511 4676057 complement(1852631..1853167) 1 NC_008767.1 hypothetical protein 1853167 4676057 NMC1815 Neisseria meningitidis FAM18 hypothetical protein YP_975756.1 1852631 R 272831 CDS YP_975757.1 121635512 4676058 complement(1853232..1854206) 1 NC_008767.1 hypothetical protein 1854206 4676058 NMC1816 Neisseria meningitidis FAM18 hypothetical protein YP_975757.1 1853232 R 272831 CDS YP_975758.1 121635513 4676049 1854303..1855358 1 NC_008767.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 1855358 tal 4676049 tal Neisseria meningitidis FAM18 transaldolase YP_975758.1 1854303 D 272831 CDS YP_975759.1 121635514 4674943 1855512..1855802 1 NC_008767.1 hypothetical protein 1855802 4674943 NMC1819 Neisseria meningitidis FAM18 hypothetical protein YP_975759.1 1855512 D 272831 CDS YP_975760.1 121635515 4676050 1855819..1856706 1 NC_008767.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 1856706 4676050 NMC1820 Neisseria meningitidis FAM18 glutamyl-Q tRNA(Asp) synthetase YP_975760.1 1855819 D 272831 CDS YP_975761.1 121635516 4676197 complement(1856776..1857786) 1 NC_008767.1 tRNA-dihydrouridine synthase A 1857786 4676197 NMC1822 Neisseria meningitidis FAM18 tRNA-dihydrouridine synthase A YP_975761.1 1856776 R 272831 CDS YP_975762.1 121635517 4676198 complement(1857817..1858308) 1 NC_008767.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1858308 4676198 NMC1823 Neisseria meningitidis FAM18 D-tyrosyl-tRNA(Tyr) deacylase YP_975762.1 1857817 R 272831 CDS YP_975763.1 121635518 4676184 complement(1858382..1859101) 1 NC_008767.1 hypothetical protein 1859101 4676184 NMC1824 Neisseria meningitidis FAM18 hypothetical protein YP_975763.1 1858382 R 272831 CDS YP_975764.1 121635519 4676185 complement(1859211..1860077) 1 NC_008767.1 hypothetical protein 1860077 4676185 NMC1825 Neisseria meningitidis FAM18 hypothetical protein YP_975764.1 1859211 R 272831 CDS YP_975765.1 121635520 4675935 complement(1860126..1860404) 1 NC_008767.1 hypothetical protein 1860404 4675935 NMC1826 Neisseria meningitidis FAM18 hypothetical protein YP_975765.1 1860126 R 272831 CDS YP_975766.2 161723297 4675936 complement(1860404..1860694) 1 NC_008767.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1860694 4675936 NMC1827 Neisseria meningitidis FAM18 hypothetical protein YP_975766.2 1860404 R 272831 CDS YP_975767.1 121635522 4676017 complement(1860697..1861245) 1 NC_008767.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1861245 4676017 NMC1828 Neisseria meningitidis FAM18 intracellular septation protein A YP_975767.1 1860697 R 272831 CDS YP_975768.1 121635523 4676018 1861433..1864060 1 NC_008767.1 hypothetical protein 1864060 tspA 4676018 tspA Neisseria meningitidis FAM18 hypothetical protein YP_975768.1 1861433 D 272831 CDS YP_975769.1 121635524 4674755 complement(1864232..1864648) 1 NC_008767.1 lactoylglutathione lyase 1864648 gloA 4674755 gloA Neisseria meningitidis FAM18 lactoylglutathione lyase YP_975769.1 1864232 R 272831 CDS YP_975770.1 121635525 4676604 complement(1864695..1865864) 1 NC_008767.1 tetratricopeptide repeat protein 1865864 4676604 NMC1831 Neisseria meningitidis FAM18 tetratricopeptide repeat protein YP_975770.1 1864695 R 272831 CDS YP_975771.1 121635526 4676160 complement(1865875..1866231) 1 NC_008767.1 hypothetical protein 1866231 4676160 NMC1832 Neisseria meningitidis FAM18 hypothetical protein YP_975771.1 1865875 R 272831 CDS YP_975772.1 121635527 4676161 1866499..1867497 1 NC_008767.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1867497 ilvE 4676161 ilvE Neisseria meningitidis FAM18 branched-chain amino acid aminotransferase YP_975772.1 1866499 D 272831 CDS YP_975773.1 121635528 4676438 complement(1867683..1868468) 1 NC_008767.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1868468 fabI 4676438 fabI Neisseria meningitidis FAM18 enoyl-ACP reductase YP_975773.1 1867683 R 272831 CDS YP_975774.1 121635529 4675841 complement(1868623..1869444) 1 NC_008767.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1869444 dapD 4675841 dapD Neisseria meningitidis FAM18 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_975774.1 1868623 R 272831 CDS YP_975775.1 121635530 4675961 complement(1869654..1871408) 1 NC_008767.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1871408 pgi 4675961 pgi Neisseria meningitidis FAM18 glucose-6-phosphate isomerase YP_975775.1 1869654 R 272831 CDS YP_975776.1 121635531 4676142 1871807..1873039 1 NC_008767.1 pilus-assembly protein 1873039 pilG 4676142 pilG Neisseria meningitidis FAM18 pilus-assembly protein YP_975776.1 1871807 D 272831 CDS YP_975777.1 121635532 4676109 1873113..1873973 1 NC_008767.1 type IV prepilin leader peptidase 1873973 pilD 4676109 pilD Neisseria meningitidis FAM18 type IV prepilin leader peptidase YP_975777.1 1873113 D 272831 CDS YP_975778.1 121635533 4676104 1873975..1874607 1 NC_008767.1 hypothetical protein 1874607 4676104 NMC1841 Neisseria meningitidis FAM18 hypothetical protein YP_975778.1 1873975 D 272831 CDS YP_975779.1 121635534 4676177 1874600..1874809 1 NC_008767.1 hypothetical protein 1874809 4676177 NMC1842 Neisseria meningitidis FAM18 hypothetical protein YP_975779.1 1874600 D 272831 CDS YP_975780.1 121635535 4676178 complement(1874894..1876570) 1 NC_008767.1 type IV pilus assembly protein 1876570 pilF 4676178 pilF Neisseria meningitidis FAM18 type IV pilus assembly protein YP_975780.1 1874894 R 272831 CDS YP_975781.1 121635536 4675956 complement(1877062..1877508) 1 NC_008767.1 hypothetical protein 1877508 4675956 NMC1845 Neisseria meningitidis FAM18 hypothetical protein YP_975781.1 1877062 R 272831 CDS YP_975782.1 121635537 4675981 complement(1877513..1878487) 1 NC_008767.1 octaprenyl-diphosphate synthase 1878487 4675981 NMC1846 Neisseria meningitidis FAM18 octaprenyl-diphosphate synthase YP_975782.1 1877513 R 272831 CDS YP_975783.1 121635538 4675982 1878711..1879019 1 NC_008767.1 50S ribosomal protein L21 1879019 rplU 4675982 rplU Neisseria meningitidis FAM18 50S ribosomal protein L21 YP_975783.1 1878711 D 272831 CDS YP_975784.1 121635539 4675373 1879044..1879316 1 NC_008767.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1879316 rpmA 4675373 rpmA Neisseria meningitidis FAM18 50S ribosomal protein L27 YP_975784.1 1879044 D 272831 CDS YP_975785.1 121635540 4675440 1879350..1880735 1 NC_008767.1 hypothetical protein 1880735 4675440 NMC1849 Neisseria meningitidis FAM18 hypothetical protein YP_975785.1 1879350 D 272831 CDS YP_975786.1 121635541 4676158 complement(1881006..1881161) 1 NC_008767.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1881161 rpmG 4676158 rpmG Neisseria meningitidis FAM18 50S ribosomal protein L33 YP_975786.1 1881006 R 272831 CDS YP_975787.1 121635542 4675294 complement(1881193..1881426) 1 NC_008767.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1881426 rpmB 4675294 rpmB Neisseria meningitidis FAM18 50S ribosomal protein L28 YP_975787.1 1881193 R 272831 CDS YP_975788.1 121635543 4675437 complement(1881676..1883226) 1 NC_008767.1 multidrug resistance translocase 1883226 emrB 4675437 emrB Neisseria meningitidis FAM18 multidrug resistance translocase YP_975788.1 1881676 R 272831 CDS YP_975789.1 121635544 4675899 complement(1883226..1884482) 1 NC_008767.1 multidrug resistance translocase 1884482 emrA 4675899 emrA Neisseria meningitidis FAM18 multidrug resistance translocase YP_975789.1 1883226 R 272831 CDS YP_975790.1 121635545 4675922 1884675..1885148 1 NC_008767.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1885148 4675922 NMC1854 Neisseria meningitidis FAM18 7-cyano-7-deazaguanine reductase YP_975790.1 1884675 D 272831 CDS YP_975791.1 121635546 4676159 1885223..1885909 1 NC_008767.1 hypothetical protein 1885909 4676159 NMC1855 Neisseria meningitidis FAM18 hypothetical protein YP_975791.1 1885223 D 272831 CDS YP_975792.1 121635547 4676148 complement(1886412..1887704) 1 NC_008767.1 hypothetical protein 1887704 4676148 NMC1856 Neisseria meningitidis FAM18 hypothetical protein YP_975792.1 1886412 R 272831 CDS YP_975793.1 121635548 4676149 1887781..1888749 1 NC_008767.1 hypothetical protein 1888749 4676149 NMC1857 Neisseria meningitidis FAM18 hypothetical protein YP_975793.1 1887781 D 272831 CDS YP_975794.1 121635549 4676154 complement(1888950..1890419) 1 NC_008767.1 hypothetical protein 1890419 4676154 NMC1858 Neisseria meningitidis FAM18 hypothetical protein YP_975794.1 1888950 R 272831 CDS YP_975795.1 121635550 4676706 1893555..1894763 1 NC_008767.1 replication initiation factor 1894763 4676706 NMC1861 Neisseria meningitidis FAM18 replication initiation factor YP_975795.1 1893555 D 272831 CDS YP_975796.1 121635551 4676162 1894784..1895095 1 NC_008767.1 hypothetical protein 1895095 4676162 NMC1862 Neisseria meningitidis FAM18 hypothetical protein YP_975796.1 1894784 D 272831 CDS YP_975797.1 121635552 4676163 1895099..1895299 1 NC_008767.1 hypothetical protein 1895299 4676163 NMC1863 Neisseria meningitidis FAM18 hypothetical protein YP_975797.1 1895099 D 272831 CDS YP_975798.1 121635553 4676113 1895537..1895767 1 NC_008767.1 hypothetical protein 1895767 4676113 NMC1864 Neisseria meningitidis FAM18 hypothetical protein YP_975798.1 1895537 D 272831 CDS YP_975799.1 121635554 4676114 1895796..1896098 1 NC_008767.1 hypothetical protein 1896098 4676114 NMC1865 Neisseria meningitidis FAM18 hypothetical protein YP_975799.1 1895796 D 272831 CDS YP_975800.1 121635555 4676025 1896545..1898050 1 NC_008767.1 TspB protein 1898050 4676025 NMC1866 Neisseria meningitidis FAM18 TspB protein YP_975800.1 1896545 D 272831 CDS YP_975801.1 121635556 4676026 1898353..1898637 1 NC_008767.1 hypothetical protein 1898637 4676026 NMC1867 Neisseria meningitidis FAM18 hypothetical protein YP_975801.1 1898353 D 272831 CDS YP_975802.1 121635557 4676004 1898638..1899825 1 NC_008767.1 hypothetical protein 1899825 4676004 NMC1868 Neisseria meningitidis FAM18 hypothetical protein YP_975802.1 1898638 D 272831 CDS YP_975803.1 121635558 4676005 1900040..1900996 1 NC_008767.1 invertase/transposase 1900996 4676005 NMC1869 Neisseria meningitidis FAM18 invertase/transposase YP_975803.1 1900040 D 272831 CDS YP_975804.1 121635559 4676037 complement(1902080..1902325) 1 NC_008767.1 hypothetical protein 1902325 4676037 NMC1870 Neisseria meningitidis FAM18 hypothetical protein YP_975804.1 1902080 R 272831 CDS YP_975805.1 121635560 4676038 1902428..1902865 1 NC_008767.1 hypothetical protein 1902865 4676038 NMC1871 Neisseria meningitidis FAM18 hypothetical protein YP_975805.1 1902428 D 272831 CDS YP_975806.1 121635561 4675906 1902862..1903353 1 NC_008767.1 hypothetical protein 1903353 4675906 NMC1872 Neisseria meningitidis FAM18 hypothetical protein YP_975806.1 1902862 D 272831 CDS YP_975807.1 121635562 4675907 complement(1903703..1904191) 1 NC_008767.1 dihydrofolate reductase 1904191 folA 4675907 folA Neisseria meningitidis FAM18 dihydrofolate reductase YP_975807.1 1903703 R 272831 CDS YP_975808.1 121635563 4676702 complement(1904259..1905314) 1 NC_008767.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1905314 aroG 4676702 aroG Neisseria meningitidis FAM18 phospho-2-dehydro-3-deoxyheptonate aldolase YP_975808.1 1904259 R 272831 CDS YP_975809.1 121635564 4675567 1905368..1905661 1 NC_008767.1 hypothetical protein 1905661 4675567 NMC1875 Neisseria meningitidis FAM18 hypothetical protein YP_975809.1 1905368 D 272831 CDS YP_975810.1 121635565 4676129 1905779..1905871 1 NC_008767.1 hypothetical protein 1905871 4676129 NMC1876 Neisseria meningitidis FAM18 hypothetical protein YP_975810.1 1905779 D 272831 CDS YP_975811.1 121635566 4676130 1905960..1906238 1 NC_008767.1 hypothetical protein 1906238 opcB 4676130 opcB Neisseria meningitidis FAM18 hypothetical protein YP_975811.1 1905960 D 272831 CDS YP_975812.1 121635567 4676082 complement(1906495..1906941) 1 NC_008767.1 hypothetical protein 1906941 4676082 NMC1879 Neisseria meningitidis FAM18 hypothetical protein YP_975812.1 1906495 R 272831 CDS YP_975813.1 121635568 4676083 complement(1907066..1907530) 1 NC_008767.1 DNA transport competence protein 1907530 4676083 NMC1880 Neisseria meningitidis FAM18 DNA transport competence protein YP_975813.1 1907066 R 272831 CDS YP_975814.1 121635569 4676116 complement(1913331..1914137) 1 NC_008767.1 hypothetical protein 1914137 4676116 NMC1882 Neisseria meningitidis FAM18 hypothetical protein YP_975814.1 1913331 R 272831 CDS YP_975815.1 121635570 4676117 1914357..1915727 1 NC_008767.1 signal recognition particle protein 1915727 ffh 4676117 ffh Neisseria meningitidis FAM18 signal recognition particle protein YP_975815.1 1914357 D 272831 CDS YP_975816.1 121635571 4676590 1916101..1917066 1 NC_008767.1 transposase for IS1655 1917066 4676590 NMC1884 Neisseria meningitidis FAM18 transposase for IS1655 YP_975816.1 1916101 D 272831 CDS YP_975817.1 121635572 4675941 complement(1917143..1917838) 1 NC_008767.1 thiol:disulfide interchange protein 1917838 4675941 NMC1885 Neisseria meningitidis FAM18 thiol:disulfide interchange protein YP_975817.1 1917143 R 272831 CDS YP_975818.1 121635573 4675942 complement(1918009..1918668) 1 NC_008767.1 hypothetical protein 1918668 4675942 NMC1886 Neisseria meningitidis FAM18 hypothetical protein YP_975818.1 1918009 R 272831 CDS YP_975819.1 121635574 4676047 complement(1918871..1920982) 1 NC_008767.1 TonB-dependent receptor protein 1920982 4676047 NMC1887 Neisseria meningitidis FAM18 TonB-dependent receptor protein YP_975819.1 1918871 R 272831 CDS YP_975820.1 121635575 4676048 complement(1921168..1921773) 1 NC_008767.1 hypothetical protein 1921773 4676048 NMC1889 Neisseria meningitidis FAM18 hypothetical protein YP_975820.1 1921168 R 272831 CDS YP_975821.1 121635576 4676090 complement(1921822..1922283) 1 NC_008767.1 hypothetical protein 1922283 4676090 NMC1890 Neisseria meningitidis FAM18 hypothetical protein YP_975821.1 1921822 R 272831 CDS YP_975822.1 121635577 4676091 1922328..1923239 1 NC_008767.1 LysR family transcriptional regulator 1923239 4676091 NMC1891 Neisseria meningitidis FAM18 LysR family transcriptional regulator YP_975822.1 1922328 D 272831 CDS YP_975823.1 121635578 4676086 1923229..1924530 1 NC_008767.1 deoxyribodopyrimidine photolyase 1924530 phr 4676086 phr Neisseria meningitidis FAM18 deoxyribodopyrimidine photolyase YP_975823.1 1923229 D 272831 CDS YP_975824.1 121635579 4676118 1924635..1925219 1 NC_008767.1 IS1106 transposase (fragment) 1925219 4676118 NMC1894 Neisseria meningitidis FAM18 IS1106 transposase (fragment) YP_975824.1 1924635 D 272831 CDS YP_975825.1 121635580 4676087 1925685..1925960 1 NC_008767.1 hypothetical protein 1925960 4676087 NMC1896 Neisseria meningitidis FAM18 hypothetical protein YP_975825.1 1925685 D 272831 CDS YP_975826.1 121635581 4676072 complement(1926177..1926971) 1 NC_008767.1 hypothetical protein 1926971 4676072 NMC1898 Neisseria meningitidis FAM18 hypothetical protein YP_975826.1 1926177 R 272831 CDS YP_975827.1 121635582 4676073 1927180..1927905 1 NC_008767.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1927905 4676073 NMC1899 Neisseria meningitidis FAM18 16S ribosomal RNA methyltransferase RsmE YP_975827.1 1927180 D 272831 CDS YP_975828.1 121635583 4676045 complement(1930082..1930888) 1 NC_008767.1 lacto-N-neotetraose biosynthesis glycosyl transferase 1930888 lgtB2 4676045 lgtB2 Neisseria meningitidis FAM18 lacto-N-neotetraose biosynthesis glycosyl transferase YP_975828.1 1930082 R 272831 CDS YP_975829.1 121635584 4675979 complement(1930930..1931025) 1 NC_008767.1 hypothetical protein 1931025 4675979 NMC1900A Neisseria meningitidis FAM18 hypothetical protein YP_975829.1 1930930 R 272831 CDS YP_975830.1 121635585 4676046 complement(1931037..1931864) 1 NC_008767.1 lacto-N-neotetraose biosynthesis glycosyl transferase 1931864 lgtB 4676046 lgtB Neisseria meningitidis FAM18 lacto-N-neotetraose biosynthesis glycosyl transferase YP_975830.1 1931037 R 272831 CDS YP_975831.1 121635586 4675978 complement(1931906..1932952) 1 NC_008767.1 lacto-N-neotetraose biosynthesis glycosyl transferase 1932952 lgtA 4675978 lgtA Neisseria meningitidis FAM18 lacto-N-neotetraose biosynthesis glycosyl transferase YP_975831.1 1931906 R 272831 CDS YP_975832.1 121635587 4676390 complement(1932969..1935032) 1 NC_008767.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1935032 glyS 4676390 glyS Neisseria meningitidis FAM18 glycyl-tRNA synthetase subunit beta YP_975832.1 1932969 R 272831 CDS YP_975833.1 121635588 4676553 complement(1935149..1936045) 1 NC_008767.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1936045 glyQ 4676553 glyQ Neisseria meningitidis FAM18 glycyl-tRNA synthetase subunit alpha YP_975833.1 1935149 R 272831 CDS YP_975834.1 121635589 4676552 complement(1936369..1936791) 1 NC_008767.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 1936791 atpC 4676552 atpC Neisseria meningitidis FAM18 ATP synthase F0F1 subunit epsilon YP_975834.1 1936369 R 272831 CDS YP_975835.1 121635590 4676545 complement(1936802..1938199) 1 NC_008767.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1938199 atpD 4676545 atpD Neisseria meningitidis FAM18 ATP synthase F0F1 subunit beta YP_975835.1 1936802 R 272831 CDS YP_975836.1 121635591 4676546 complement(1938237..1939112) 1 NC_008767.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1939112 atpG 4676546 atpG Neisseria meningitidis FAM18 ATP synthase F0F1 subunit gamma YP_975836.1 1938237 R 272831 CDS YP_975837.1 121635592 4675645 complement(1939137..1940684) 1 NC_008767.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1940684 atpA 4675645 atpA Neisseria meningitidis FAM18 ATP synthase F0F1 subunit alpha YP_975837.1 1939137 R 272831 CDS YP_975838.1 121635593 4675633 complement(1940695..1941228) 1 NC_008767.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 1941228 atpH 4675633 atpH Neisseria meningitidis FAM18 ATP synthase F0F1 subunit delta YP_975838.1 1940695 R 272831 CDS YP_975839.1 121635594 4675646 complement(1941233..1941703) 1 NC_008767.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 1941703 atpF 4675646 atpF Neisseria meningitidis FAM18 ATP synthase F0F1 subunit B YP_975839.1 1941233 R 272831 CDS YP_975840.1 121635595 4675670 complement(1941774..1942010) 1 NC_008767.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 1942010 atpE 4675670 atpE Neisseria meningitidis FAM18 ATP synthase F0F1 subunit C YP_975840.1 1941774 R 272831 CDS YP_975841.1 121635596 4675669 complement(1942067..1942933) 1 NC_008767.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 1942933 atpB 4675669 atpB Neisseria meningitidis FAM18 ATP synthase F0F1 subunit A YP_975841.1 1942067 R 272831 CDS YP_975842.1 121635597 4675634 complement(1942923..1943276) 1 NC_008767.1 ATP synthase I 1943276 atpI 4675634 atpI Neisseria meningitidis FAM18 ATP synthase I YP_975842.1 1942923 R 272831 CDS YP_975843.1 121635598 4676675 complement(1943644..1943982) 1 NC_008767.1 hypothetical protein 1943982 4676675 NMC1914 Neisseria meningitidis FAM18 hypothetical protein YP_975843.1 1943644 R 272831 CDS YP_975844.1 121635599 4676076 complement(1944117..1944977) 1 NC_008767.1 chromosome segregation proteins 1944977 4676076 NMC1915 Neisseria meningitidis FAM18 chromosome segregation proteins YP_975844.1 1944117 R 272831 CDS YP_975845.1 121635600 4676077 1945033..1945704 1 NC_008767.1 aromatic acid decarboxylase 1945704 4676077 NMC1916 Neisseria meningitidis FAM18 aromatic acid decarboxylase YP_975845.1 1945033 D 272831 CDS YP_975846.1 121635601 4675988 complement(1945766..1946629) 1 NC_008767.1 lipoprotein 1946629 4675988 NMC1917 Neisseria meningitidis FAM18 lipoprotein YP_975846.1 1945766 R 272831 CDS YP_975847.1 121635602 4675989 complement(1946788..1947474) 1 NC_008767.1 inner membrane transport protein 1947474 4675989 NMC1918 Neisseria meningitidis FAM18 inner membrane transport protein YP_975847.1 1946788 R 272831 CDS YP_975848.1 121635603 4675849 complement(1947477..1948214) 1 NC_008767.1 ABC transport ATP-binding subunit 1948214 4675849 NMC1919 Neisseria meningitidis FAM18 ABC transport ATP-binding subunit YP_975848.1 1947477 R 272831 CDS YP_975849.1 121635604 4675850 1948745..1950592 1 NC_008767.1 transglycosylase 1950592 4675850 NMC1920 Neisseria meningitidis FAM18 transglycosylase YP_975849.1 1948745 D 272831 CDS YP_975850.1 121635605 4676070 1950881..1951093 1 NC_008767.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1951093 rpsU 4676070 rpsU Neisseria meningitidis FAM18 30S ribosomal protein S21 YP_975850.1 1950881 D 272831 CDS YP_975851.1 121635606 4675123 1951267..1951671 1 NC_008767.1 hypothetical protein 1951671 4675123 NMC1922 Neisseria meningitidis FAM18 hypothetical protein YP_975851.1 1951267 D 272831 CDS YP_975852.1 121635607 4676071 complement(1951996..1952451) 1 NC_008767.1 ClpXP protease specificity-enhancing factor 1952451 regG 4676071 regG Neisseria meningitidis FAM18 ClpXP protease specificity-enhancing factor YP_975852.1 1951996 R 272831 CDS YP_975853.1 121635608 4675746 complement(1952459..1953064) 1 NC_008767.1 regulator of pilE expression 1953064 regF 4675746 regF Neisseria meningitidis FAM18 regulator of pilE expression YP_975853.1 1952459 R 272831 CDS YP_975854.1 121635609 4675672 complement(1953334..1955046) 1 NC_008767.1 hypothetical protein 1955046 4675672 NMC1926 Neisseria meningitidis FAM18 hypothetical protein YP_975854.1 1953334 R 272831 CDS YP_975855.1 121635610 4676061 complement(1955151..1955792) 1 NC_008767.1 cadmium resistance protein 1955792 4676061 NMC1927 Neisseria meningitidis FAM18 cadmium resistance protein YP_975855.1 1955151 R 272831 CDS YP_975856.2 161723296 4676062 complement(1956095..1956310) 1 NC_008767.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1956310 rpmE 4676062 rpmE Neisseria meningitidis FAM18 50S ribosomal protein L31 YP_975856.2 1956095 R 272831 CDS YP_975857.1 121635612 4675434 join(1956545..1956856,1956856..1957062) 1 NC_008767.1 acetyltransferase 1957062 4675434 NMC1929 Neisseria meningitidis FAM18 acetyltransferase YP_975857.1 1956545 D 272831 CDS YP_975858.1 121635613 4676059 complement(1957146..1957634) 1 NC_008767.1 hypothetical protein 1957634 4676059 NMC1930 Neisseria meningitidis FAM18 hypothetical protein YP_975858.1 1957146 R 272831 CDS YP_975859.1 121635614 4676060 complement(1957631..1958014) 1 NC_008767.1 hypothetical protein 1958014 4676060 NMC1931 Neisseria meningitidis FAM18 hypothetical protein YP_975859.1 1957631 R 272831 CDS YP_975860.1 121635615 4676042 complement(1958014..1958496) 1 NC_008767.1 hypothetical protein 1958496 4676042 NMC1932 Neisseria meningitidis FAM18 hypothetical protein YP_975860.1 1958014 R 272831 CDS YP_975861.1 121635616 4676043 complement(1958501..1959328) 1 NC_008767.1 periplasmic/outer membrane protein 1959328 4676043 NMC1933 Neisseria meningitidis FAM18 periplasmic/outer membrane protein YP_975861.1 1958501 R 272831 CDS YP_975862.1 121635617 4676012 complement(1959325..1959627) 1 NC_008767.1 hypothetical protein 1959627 4676012 NMC1934 Neisseria meningitidis FAM18 hypothetical protein YP_975862.1 1959325 R 272831 CDS YP_975863.1 121635618 4676013 complement(1959660..1960250) 1 NC_008767.1 periplasmic transport protein 1960250 4676013 NMC1935 Neisseria meningitidis FAM18 periplasmic transport protein YP_975863.1 1959660 R 272831 CDS YP_975864.1 121635619 4675997 complement(1960287..1960766) 1 NC_008767.1 outer membrane transport protein 1960766 4675997 NMC1936 Neisseria meningitidis FAM18 outer membrane transport protein YP_975864.1 1960287 R 272831 CDS YP_975865.1 121635620 4675998 complement(1960832..1961608) 1 NC_008767.1 ABC transport inner membrane subunit 1961608 4675998 NMC1937 Neisseria meningitidis FAM18 ABC transport inner membrane subunit YP_975865.1 1960832 R 272831 CDS YP_975866.1 121635621 4676033 complement(1961657..1962517) 1 NC_008767.1 ABC transport ATP-binding protein 1962517 4676033 NMC1938 Neisseria meningitidis FAM18 ABC transport ATP-binding protein YP_975866.1 1961657 R 272831 CDS YP_975867.1 121635622 4676034 join(1962630..1963049,1963053..1963289,1963285..1963449,1963451..1963543) 1 NC_008767.1 transcriptional regulator 1963543 4676034 NMC1939 Neisseria meningitidis FAM18 transcriptional regulator YP_975867.1 1962630 D 272831 CDS YP_975868.1 121635623 4675986 1963751..1964140 1 NC_008767.1 hypothetical protein 1964140 4675986 NMC1940 Neisseria meningitidis FAM18 hypothetical protein YP_975868.1 1963751 D 272831 CDS YP_975869.1 121635624 4675987 1964149..1964349 1 NC_008767.1 hypothetical protein 1964349 4675987 NMC1941 Neisseria meningitidis FAM18 hypothetical protein YP_975869.1 1964149 D 272831 CDS YP_975870.1 121635625 4675715 1964384..1965826 1 NC_008767.1 NAD-linked; aldehyde dehydrogenase 1965826 aldA 4675715 aldA Neisseria meningitidis FAM18 aldehyde dehydrogenase YP_975870.1 1964384 D 272831 CDS YP_975871.1 121635626 4676385 join(1967026..1967313,1967313..1970228) 1 NC_008767.1 outer membrane peptidase 1970228 4676385 NMC1943 Neisseria meningitidis FAM18 outer membrane peptidase YP_975871.1 1967026 D 272831 CDS YP_975872.1 121635627 4675716 1971412..1973208 1 NC_008767.1 para-aminobenzoate synthase component I 1973208 4675716 NMC1944 Neisseria meningitidis FAM18 para-aminobenzoate synthase component I YP_975872.1 1971412 D 272831 CDS YP_975873.1 121635628 4675713 complement(1973267..1974784) 1 NC_008767.1 hypothetical protein 1974784 4675713 NMC1945 Neisseria meningitidis FAM18 hypothetical protein YP_975873.1 1973267 R 272831 CDS YP_975874.1 121635629 4675714 1975529..1976554 1 NC_008767.1 hemoglobin-haptoglobin-utilization protein 1976554 hpuA 4675714 hpuA Neisseria meningitidis FAM18 hemoglobin-haptoglobin-utilization protein YP_975874.1 1975529 D 272831 CDS YP_975875.1 121635630 4676377 1976585..1979017 1 NC_008767.1 hemoglobin-haptoglobin-utilization protein 1979017 hpuB 4676377 hpuB Neisseria meningitidis FAM18 hemoglobin-haptoglobin-utilization protein YP_975875.1 1976585 D 272831 CDS YP_975876.1 121635631 4676463 complement(1979605..1981239) 1 NC_008767.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 1981239 groEL 4676463 groEL Neisseria meningitidis FAM18 molecular chaperone GroEL YP_975876.1 1979605 R 272831 CDS YP_975877.1 121635632 4676481 complement(1981332..1981658) 1 NC_008767.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1981658 groES 4676481 groES Neisseria meningitidis FAM18 co-chaperonin GroES YP_975877.1 1981332 R 272831 CDS YP_975878.1 121635633 4676250 1981852..1982505 1 NC_008767.1 insertion element IS1016 transposase 1982505 4676250 NMC1950 Neisseria meningitidis FAM18 insertion element IS1016 transposase YP_975878.1 1981852 D 272831 CDS YP_975879.1 121635634 4675710 1982622..1984253 1 NC_008767.1 sodium-dependent inner membrane transport protein 1984253 4675710 NMC1951 Neisseria meningitidis FAM18 sodium-dependent inner membrane transport protein YP_975879.1 1982622 D 272831 CDS YP_975880.1 121635635 4675711 complement(1984378..1985622) 1 NC_008767.1 diaminopimelate decarboxylase 1985622 lysA 4675711 lysA Neisseria meningitidis FAM18 diaminopimelate decarboxylase YP_975880.1 1984378 R 272831 CDS YP_975881.1 121635636 4676339 complement(1985633..1985803) 1 NC_008767.1 lipoprotein 1985803 4676339 NMC1953 Neisseria meningitidis FAM18 lipoprotein YP_975881.1 1985633 R 272831 CDS YP_975882.1 121635637 4675707 1985874..1986197 1 NC_008767.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 1986197 cyaY 4675707 cyaY Neisseria meningitidis FAM18 frataxin-like protein YP_975882.1 1985874 D 272831 CDS YP_975883.1 121635638 4675708 1986228..1986647 1 NC_008767.1 hypothetical protein 1986647 4675708 NMC1955 Neisseria meningitidis FAM18 hypothetical protein YP_975883.1 1986228 D 272831 CDS YP_975884.1 121635639 4676172 1986669..1987175 1 NC_008767.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1987175 4676172 NMC1956 Neisseria meningitidis FAM18 S-ribosylhomocysteinase YP_975884.1 1986669 D 272831 CDS YP_975885.1 121635640 4676173 1987321..1990113 1 NC_008767.1 DNA polymerase I 1990113 polA 4676173 polA Neisseria meningitidis FAM18 DNA polymerase I YP_975885.1 1987321 D 272831 CDS YP_975886.1 121635641 4676092 1991459..1992181 1 NC_008767.1 hypothetical protein 1992181 4676092 NMC1958 Neisseria meningitidis FAM18 hypothetical protein YP_975886.1 1991459 D 272831 CDS YP_975887.1 121635642 4674929 complement(1992290..1996654) 1 NC_008767.1 IgA-specific serine endopeptidase 1996654 iga2 4674929 iga2 Neisseria meningitidis FAM18 IgA-specific serine endopeptidase YP_975887.1 1992290 R 272831 CDS YP_975888.1 121635643 4676439 complement(1996788..1997219) 1 NC_008767.1 hypothetical protein 1997219 4676439 NMC1960 Neisseria meningitidis FAM18 hypothetical protein YP_975888.1 1996788 R 272831 CDS YP_975889.1 121635644 4674930 complement(1997216..1997371) 1 NC_008767.1 hypothetical protein 1997371 4674930 NMC1961 Neisseria meningitidis FAM18 hypothetical protein YP_975889.1 1997216 R 272831 CDS YP_975890.1 121635645 4674878 1997502..1998848 1 NC_008767.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1998848 trmE 4674878 trmE Neisseria meningitidis FAM18 tRNA modification GTPase TrmE YP_975890.1 1997502 D 272831 CDS YP_975891.1 121635646 4675204 2000909..2003053 1 NC_008767.1 iron-regulated outer membrane protein 2003053 fetA 4675204 fetA Neisseria meningitidis FAM18 iron-regulated outer membrane protein YP_975891.1 2000909 D 272831 CDS YP_975892.1 121635647 4675149 2003309..2004322 1 NC_008767.1 membrane transport solute-binding protein 2004322 fetB 4675149 fetB Neisseria meningitidis FAM18 membrane transport solute-binding protein YP_975892.1 2003309 D 272831 CDS YP_975893.1 121635648 4675150 2004789..2005622 1 NC_008767.1 inner membrane transport protein 2005622 4675150 NMC1965 Neisseria meningitidis FAM18 inner membrane transport protein YP_975893.1 2004789 D 272831 CDS YP_975894.1 121635649 4674879 2005612..2006586 1 NC_008767.1 inner membrane transport protein 2006586 4674879 NMC1966 Neisseria meningitidis FAM18 inner membrane transport protein YP_975894.1 2005612 D 272831 CDS YP_975895.1 121635650 4675157 2006631..2007257 1 NC_008767.1 hypothetical protein 2007257 4675157 NMC1967 Neisseria meningitidis FAM18 hypothetical protein YP_975895.1 2006631 D 272831 CDS YP_975896.1 121635651 4675158 2007342..2008100 1 NC_008767.1 ABC transporter ATP-binding subunit 2008100 4675158 NMC1968 Neisseria meningitidis FAM18 ABC transporter ATP-binding subunit YP_975896.1 2007342 D 272831 CDS YP_975897.1 121635652 4675703 2008404..2009600 1 NC_008767.1 adhesin/invasin 2009600 4675703 NMC1969 Neisseria meningitidis FAM18 adhesin/invasin YP_975897.1 2008404 D 272831 CDS YP_975898.1 121635653 4675704 complement(2009666..2010004) 1 NC_008767.1 nitrogen regulatory protein P-II 1 2010004 glnB 4675704 glnB Neisseria meningitidis FAM18 nitrogen regulatory protein P-II 1 YP_975898.1 2009666 R 272831 CDS YP_975899.1 121635654 4676582 2010140..2014117 1 NC_008767.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2014117 purL 4676582 purL Neisseria meningitidis FAM18 phosphoribosylformylglycinamidine synthase YP_975899.1 2010140 D 272831 CDS YP_975900.1 121635655 4675794 2014212..2014970 1 NC_008767.1 hydroxyacylglutathione hydrolase 2014970 4675794 NMC1973 Neisseria meningitidis FAM18 hydroxyacylglutathione hydrolase YP_975900.1 2014212 D 272831 CDS YP_975901.1 121635656 4675702 2019991..2021445 1 NC_008767.1 hypothetical protein 2021445 4675702 NMC1976 Neisseria meningitidis FAM18 hypothetical protein YP_975901.1 2019991 D 272831 CDS YP_975902.1 121635657 4674817 complement(2021531..2022532) 1 NC_008767.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 2022532 hslO 4674817 hslO Neisseria meningitidis FAM18 heat shock protein 33 YP_975902.1 2021531 R 272831 CDS YP_975903.1 121635658 4674818 2022684..2023439 1 NC_008767.1 hypothetical protein 2023439 4674818 NMC1978 Neisseria meningitidis FAM18 hypothetical protein YP_975903.1 2022684 D 272831 CDS YP_975904.1 121635659 4674820 2023458..2023676 1 NC_008767.1 hypothetical protein 2023676 4674820 NMC1979 Neisseria meningitidis FAM18 hypothetical protein YP_975904.1 2023458 D 272831 CDS YP_975905.1 121635660 4674821 2023821..2024165 1 NC_008767.1 hypothetical protein 2024165 4674821 NMC1980 Neisseria meningitidis FAM18 hypothetical protein YP_975905.1 2023821 D 272831 CDS YP_975906.1 121635661 4675268 2024165..2024857 1 NC_008767.1 hypothetical protein 2024857 4675268 NMC1981 Neisseria meningitidis FAM18 hypothetical protein YP_975906.1 2024165 D 272831 CDS YP_975907.1 121635662 4675269 2024924..2026144 1 NC_008767.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 2026144 argJ 4675269 argJ Neisseria meningitidis FAM18 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_975907.1 2024924 D 272831 CDS YP_975908.1 121635663 4676239 2026291..2027613 1 NC_008767.1 hypothetical protein 2027613 4676239 NMC1983 Neisseria meningitidis FAM18 hypothetical protein YP_975908.1 2026291 D 272831 CDS YP_975909.1 121635664 4674880 2027802..2029193 1 NC_008767.1 ATP-dependent DNA helicase 2029193 4674880 NMC1984 Neisseria meningitidis FAM18 ATP-dependent DNA helicase YP_975909.1 2027802 D 272831 CDS YP_975910.1 121635665 4674881 2029294..2030421 1 NC_008767.1 hypothetical protein 2030421 4674881 NMC1985 Neisseria meningitidis FAM18 hypothetical protein YP_975910.1 2029294 D 272831 CDS YP_975911.1 121635666 4674797 2030602..2032176 1 NC_008767.1 hypothetical protein 2032176 4674797 NMC1986 Neisseria meningitidis FAM18 hypothetical protein YP_975911.1 2030602 D 272831 CDS YP_975912.1 121635667 4674798 2032242..2035541 1 NC_008767.1 DNA helicase 2035541 4674798 NMC1987 Neisseria meningitidis FAM18 DNA helicase YP_975912.1 2032242 D 272831 CDS YP_975913.1 121635668 4674782 complement(2035564..2035950) 1 NC_008767.1 patch repair protein 2035950 vsr 4674782 vsr Neisseria meningitidis FAM18 patch repair protein YP_975913.1 2035564 R 272831 CDS YP_975914.1 121635669 4676537 complement(2035990..2037672) 1 NC_008767.1 hypothetical protein 2037672 4676537 NMC1991 Neisseria meningitidis FAM18 hypothetical protein YP_975914.1 2035990 R 272831 CDS YP_975915.1 121635670 4674783 complement(2037650..2038705) 1 NC_008767.1 deleted EC_number 2.1.1.73; cytosine-specific DNA methylase 2038705 4674783 NMC1992 Neisseria meningitidis FAM18 cytosine-specific DNA methylase YP_975915.1 2037650 R 272831 CDS YP_975916.1 121635671 4675258 2039326..2040291 1 NC_008767.1 insertion element IS1655 transposase 2040291 4675258 NMC1993 Neisseria meningitidis FAM18 insertion element IS1655 transposase YP_975916.1 2039326 D 272831 CDS YP_975917.1 121635672 4675259 2040934..2041203 1 NC_008767.1 hypothetical protein 2041203 4675259 NMC1994 Neisseria meningitidis FAM18 hypothetical protein YP_975917.1 2040934 D 272831 CDS YP_975918.1 121635673 4676450 complement(2041364..2041813) 1 NC_008767.1 pilin 2041813 4676450 NMC1995 Neisseria meningitidis FAM18 pilin YP_975918.1 2041364 R 272831 CDS YP_975919.1 121635674 4676451 complement(2041901..2042365) 1 NC_008767.1 DNA transport competence protein 2042365 4676451 NMC1996 Neisseria meningitidis FAM18 DNA transport competence protein YP_975919.1 2041901 R 272831 CDS YP_975920.1 121635675 4674925 complement(2048049..2048759) 1 NC_008767.1 psedouridine synthase 2048759 4674925 NMC1997 Neisseria meningitidis FAM18 psedouridine synthase YP_975920.1 2048049 R 272831 CDS YP_975921.1 121635676 4674926 complement(2048734..2049246) 1 NC_008767.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 2049246 coaD 4674926 coaD Neisseria meningitidis FAM18 phosphopantetheine adenylyltransferase YP_975921.1 2048734 R 272831 CDS YP_975922.1 121635677 4676419 complement(2049370..2050053) 1 NC_008767.1 hypothetical protein 2050053 4676419 NMC1999 Neisseria meningitidis FAM18 hypothetical protein YP_975922.1 2049370 R 272831 CDS YP_975923.1 121635678 4675647 complement(2050210..2050476) 1 NC_008767.1 hypothetical protein 2050476 4675647 NMC2000 Neisseria meningitidis FAM18 hypothetical protein YP_975923.1 2050210 R 272831 CDS YP_975924.1 121635679 4675648 complement(2050551..2051021) 1 NC_008767.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2051021 4675648 NMC2001 Neisseria meningitidis FAM18 rRNA large subunit methyltransferase YP_975924.1 2050551 R 272831 CDS YP_975925.1 121635680 4676631 complement(2051075..2051461) 1 NC_008767.1 hypothetical protein 2051461 4676631 NMC2002 Neisseria meningitidis FAM18 hypothetical protein YP_975925.1 2051075 R 272831 CDS YP_975926.1 121635681 4676632 complement(2051520..2052125) 1 NC_008767.1 hypothetical protein 2052125 4676632 NMC2003 Neisseria meningitidis FAM18 hypothetical protein YP_975926.1 2051520 R 272831 CDS YP_975927.1 121635682 4675291 complement(2052122..2052721) 1 NC_008767.1 hypothetical protein 2052721 4675291 NMC2004 Neisseria meningitidis FAM18 hypothetical protein YP_975927.1 2052122 R 272831 CDS YP_975928.1 121635683 4675292 complement(2052750..2054342) 1 NC_008767.1 permease 2054342 4675292 NMC2005 Neisseria meningitidis FAM18 permease YP_975928.1 2052750 R 272831 CDS YP_975929.1 121635684 4675691 2054682..2056067 1 NC_008767.1 gluconate permease 2056067 gntP 4675691 gntP Neisseria meningitidis FAM18 gluconate permease YP_975929.1 2054682 D 272831 CDS YP_975930.1 121635685 4675983 2056087..2056605 1 NC_008767.1 glucokinase 2056605 4675983 NMC2007 Neisseria meningitidis FAM18 glucokinase YP_975930.1 2056087 D 272831 CDS YP_975931.1 121635686 4675692 complement(2056944..2057861) 1 NC_008767.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase 2057861 thrB 4675692 thrB Neisseria meningitidis FAM18 homoserine kinase YP_975931.1 2056944 R 272831 CDS YP_975932.1 121635687 4675197 complement(2057898..2058647) 1 NC_008767.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2058647 ubiG 4675197 ubiG Neisseria meningitidis FAM18 3-demethylubiquinone-9 3-methyltransferase YP_975932.1 2057898 R 272831 CDS YP_975933.1 121635688 4676474 2058778..2060019 1 NC_008767.1 amino-acid transport protein 2060019 4676474 NMC2010 Neisseria meningitidis FAM18 amino-acid transport protein YP_975933.1 2058778 D 272831 CDS YP_975934.1 121635689 4675685 2060077..2061135 1 NC_008767.1 protein LgtG 2061135 4675685 NMC2011 Neisseria meningitidis FAM18 protein LgtG YP_975934.1 2060077 D 272831 CDS YP_975935.1 121635690 4675686 complement(2061202..2062854) 1 NC_008767.1 hypothetical protein 2062854 4675686 NMC2012 Neisseria meningitidis FAM18 hypothetical protein YP_975935.1 2061202 R 272831 CDS YP_975936.1 121635691 4675697 join(2063024..2063266,2063266..2063595) 1 NC_008767.1 hypothetical protein 2063595 4675697 NMC2013 Neisseria meningitidis FAM18 hypothetical protein YP_975936.1 2063024 D 272831 CDS YP_975937.1 121635692 4675698 2063592..2064155 1 NC_008767.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 2064155 4675698 NMC2014 Neisseria meningitidis FAM18 D,D-heptose 1,7-bisphosphate phosphatase YP_975937.1 2063592 D 272831 CDS YP_975938.1 121635693 4675393 2064185..2064928 1 NC_008767.1 1-acyl-SN-glycerol-3-phosphate acyltransferase 2064928 nlaB 4675393 nlaB Neisseria meningitidis FAM18 1-acyl-SN-glycerol-3-phosphate acyltransferase YP_975938.1 2064185 D 272831 CDS YP_975939.1 121635694 4676226 2064925..2065617 1 NC_008767.1 hypothetical protein 2065617 4676226 NMC2016 Neisseria meningitidis FAM18 hypothetical protein YP_975939.1 2064925 D 272831 CDS YP_975940.1 121635695 4675394 2067123..2067920 1 NC_008767.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2067920 truA 4675394 truA Neisseria meningitidis FAM18 tRNA pseudouridine synthase A YP_975940.1 2067123 D 272831 CDS YP_975941.1 121635696 4675185 2068043..2068282 1 NC_008767.1 hypothetical protein 2068282 4675185 NMC2018 Neisseria meningitidis FAM18 hypothetical protein YP_975941.1 2068043 D 272831 CDS YP_975942.1 121635697 4676692 2068270..2068593 1 NC_008767.1 PEMK-like protein 2068593 chpA 4676692 chpA Neisseria meningitidis FAM18 PEMK-like protein YP_975942.1 2068270 D 272831 CDS YP_975943.1 121635698 4676662 2069294..2070508 1 NC_008767.1 porin 2070508 porB 4676662 porB Neisseria meningitidis FAM18 porin YP_975943.1 2069294 D 272831 CDS YP_975944.1 121635699 4676064 complement(2072542..2074443) 1 NC_008767.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 2074443 thiC 4676064 thiC Neisseria meningitidis FAM18 thiamine biosynthesis protein ThiC YP_975944.1 2072542 R 272831 CDS YP_975945.1 121635700 4674912 2075041..2075916 1 NC_008767.1 hypothetical protein 2075916 4674912 NMC2022 Neisseria meningitidis FAM18 hypothetical protein YP_975945.1 2075041 D 272831 CDS YP_975946.1 121635701 4676693 2075925..2076863 1 NC_008767.1 ABC transporter ATP-binding protein 2076863 4676693 NMC2023 Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_975946.1 2075925 D 272831 CDS YP_975947.1 121635702 4676530 complement(2078138..2079913) 1 NC_008767.1 phosphoenolpyruvate-protein phosphotransferase 2079913 ptsI 4676530 ptsI Neisseria meningitidis FAM18 phosphoenolpyruvate-protein phosphotransferase YP_975947.1 2078138 R 272831 CDS YP_975948.1 121635703 4676011 complement(2079913..2080182) 1 NC_008767.1 sugar transport PTS system phosphocarrier protein HPr 2080182 ptsH 4676011 ptsH Neisseria meningitidis FAM18 sugar transport PTS system phosphocarrier protein HPr YP_975948.1 2079913 R 272831 CDS YP_975949.1 121635704 4676010 complement(2080251..2080688) 1 NC_008767.1 sugar transport PTS system IIA component 2080688 4676010 NMC2026 Neisseria meningitidis FAM18 sugar transport PTS system IIA component YP_975949.1 2080251 R 272831 CDS YP_975950.1 121635705 4676531 complement(2080769..2081332) 1 NC_008767.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 2081332 hpt 4676531 hpt Neisseria meningitidis FAM18 hypoxanthine-guanine phosphoribosyltransferase YP_975950.1 2080769 R 272831 CDS YP_975951.1 121635706 4676376 complement(2081401..2082225) 1 NC_008767.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase 2082225 4676376 NMC2028 Neisseria meningitidis FAM18 DNA ligase YP_975951.1 2081401 R 272831 CDS YP_975952.1 121635707 4675270 2082284..2082949 1 NC_008767.1 hydrolase 2082949 4675270 NMC2029 Neisseria meningitidis FAM18 hydrolase YP_975952.1 2082284 D 272831 CDS YP_975953.1 121635708 4675271 complement(2083156..2084940) 1 NC_008767.1 hypothetical protein 2084940 4675271 NMC2030 Neisseria meningitidis FAM18 hypothetical protein YP_975953.1 2083156 R 272831 CDS YP_975954.1 121635709 4675695 complement(2085279..2086082) 1 NC_008767.1 cytochrome C1 precursor 2086082 petC 4675695 petC Neisseria meningitidis FAM18 cytochrome C1 precursor YP_975954.1 2085279 R 272831 CDS YP_975955.1 121635710 4676153 complement(2086082..2087431) 1 NC_008767.1 cytochrome B 2087431 petB 4676153 petB Neisseria meningitidis FAM18 cytochrome B YP_975955.1 2086082 R 272831 CDS YP_975956.1 121635711 4676152 complement(2087450..2088031) 1 NC_008767.1 ubiquinol-cytochrome c reductase iron-sulfur subunit 2088031 petA 4676152 petA Neisseria meningitidis FAM18 ubiquinol-cytochrome c reductase iron-sulfur subunit YP_975956.1 2087450 R 272831 CDS YP_975957.1 121635712 4675894 complement(2088154..2088963) 1 NC_008767.1 hypothetical protein 2088963 4675894 NMC2035 Neisseria meningitidis FAM18 hypothetical protein YP_975957.1 2088154 R 272831 CDS YP_975958.1 121635713 4675696 2089034..2089963 1 NC_008767.1 transcriptional activator protein METR 2089963 metR 4675696 metR Neisseria meningitidis FAM18 transcriptional activator protein METR YP_975958.1 2089034 D 272831 CDS YP_975959.1 121635714 4676315 complement(2090219..2090611) 1 NC_008767.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 2090611 rpsI 4676315 rpsI Neisseria meningitidis FAM18 30S ribosomal protein S9 YP_975959.1 2090219 R 272831 CDS YP_975960.1 121635715 4675134 complement(2090621..2091052) 1 NC_008767.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 2091052 rplM 4675134 rplM Neisseria meningitidis FAM18 50S ribosomal protein L13 YP_975960.1 2090621 R 272831 CDS YP_975961.1 121635716 4675469 complement(2091415..2091720) 1 NC_008767.1 hypothetical protein 2091720 4675469 NMC2039 Neisseria meningitidis FAM18 hypothetical protein YP_975961.1 2091415 R 272831 CDS YP_975962.1 121635717 4674774 complement(2091731..2092060) 1 NC_008767.1 hypothetical protein 2092060 4674774 NMC2040 Neisseria meningitidis FAM18 hypothetical protein YP_975962.1 2091731 R 272831 CDS YP_975963.1 121635718 4674775 complement(2092115..2093104) 1 NC_008767.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2093104 gpsA 4674775 gpsA Neisseria meningitidis FAM18 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_975963.1 2092115 R 272831 CDS YP_975964.1 121635719 4676522 complement(2093227..2095929) 1 NC_008767.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 2095929 ppc 4676522 ppc Neisseria meningitidis FAM18 phosphoenolpyruvate carboxylase YP_975964.1 2093227 R 272831 CDS YP_975965.1 121635720 4676081 2095918..2096865 1 NC_008767.1 thiazole biosynthesis adenylyltransferase ThiF 2096865 thiF 4676081 thiF Neisseria meningitidis FAM18 thiazole biosynthesis adenylyltransferase ThiF YP_975965.1 2095918 D 272831 CDS YP_975966.1 121635721 4675202 complement(2097563..2097787) 1 NC_008767.1 hypothetical protein 2097787 slyX 4675202 slyX Neisseria meningitidis FAM18 hypothetical protein YP_975966.1 2097563 R 272831 CDS YP_975967.1 121635722 4675061 complement(2097788..2099176) 1 NC_008767.1 hypothetical protein 2099176 4675061 NMC2045 Neisseria meningitidis FAM18 hypothetical protein YP_975967.1 2097788 R 272831 CDS YP_975968.1 121635723 4675397 complement(2099262..2100533) 1 NC_008767.1 hemk protein 2100533 4675397 NMC2046 Neisseria meningitidis FAM18 hemk protein YP_975968.1 2099262 R 272831 CDS YP_975969.1 121635724 4675398 complement(2100598..2102082) 1 NC_008767.1 TLDD protein 2102082 tldD 4675398 tldD Neisseria meningitidis FAM18 TLDD protein YP_975969.1 2100598 R 272831 CDS YP_975970.1 121635725 4674865 2102430..2103653 1 NC_008767.1 permease 2103653 4674865 NMC2048 Neisseria meningitidis FAM18 permease YP_975970.1 2102430 D 272831 CDS YP_975971.1 121635726 4676348 2103650..2104750 1 NC_008767.1 oxidoreductase 2104750 4676348 NMC2049 Neisseria meningitidis FAM18 oxidoreductase YP_975971.1 2103650 D 272831 CDS YP_975972.1 121635727 4676349 2104771..2105388 1 NC_008767.1 thiamin-phosphate pyrophosphorylase 2105388 thiE 4676349 thiE Neisseria meningitidis FAM18 thiamin-phosphate pyrophosphorylase YP_975972.1 2104771 D 272831 CDS YP_975973.1 121635728 4675201 2105811..2106005 1 NC_008767.1 hypothetical protein 2106005 4675201 NMC2051 Neisseria meningitidis FAM18 hypothetical protein YP_975973.1 2105811 D 272831 CDS YP_975974.1 121635729 4675550 2106219..2107007 1 NC_008767.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 2107007 thiG 4675550 thiG Neisseria meningitidis FAM18 thiazole synthase YP_975974.1 2106219 D 272831 CDS YP_975975.1 121635730 4675199 complement(2107770..2108594) 1 NC_008767.1 hypothetical protein 2108594 4675199 NMC2053 Neisseria meningitidis FAM18 hypothetical protein YP_975975.1 2107770 R 272831 CDS YP_975976.1 121635731 4675551 complement(2108707..2110485) 1 NC_008767.1 activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins and catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; bifunctional biotin--[acetyl-CoA-carboxylase] ligase/pantothenate kinase 2110485 birA 4675551 birA Neisseria meningitidis FAM18 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/pantothenate kinase YP_975976.1 2108707 R 272831 CDS YP_975977.1 121635732 4676524 complement(2110482..2110919) 1 NC_008767.1 transferase 2110919 4676524 NMC2055 Neisseria meningitidis FAM18 transferase YP_975977.1 2110482 R 272831 CDS YP_975978.1 121635733 4675532 2111628..2112482 1 NC_008767.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2112482 folD 4675532 folD Neisseria meningitidis FAM18 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_975978.1 2111628 D 272831 CDS YP_975979.1 121635734 4676699 complement(2112544..2113125) 1 NC_008767.1 hypothetical protein 2113125 4676699 NMC2057 Neisseria meningitidis FAM18 hypothetical protein YP_975979.1 2112544 R 272831 CDS YP_975980.1 121635735 4675533 2113301..2114416 1 NC_008767.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 2114416 4675533 NMC2058 Neisseria meningitidis FAM18 aspartate-semialdehyde dehydrogenase YP_975980.1 2113301 D 272831 CDS YP_975981.1 121635736 4675687 complement(2114509..2115039) 1 NC_008767.1 hypothetical protein 2115039 4675687 NMC2059 Neisseria meningitidis FAM18 hypothetical protein YP_975981.1 2114509 R 272831 CDS YP_975982.1 121635737 4675688 complement(2115050..2115394) 1 NC_008767.1 hypothetical protein 2115394 4675688 NMC2060 Neisseria meningitidis FAM18 hypothetical protein YP_975982.1 2115050 R 272831 CDS YP_975983.1 121635738 4675281 complement(2115381..2116160) 1 NC_008767.1 nuclease 2116160 4675281 NMC2061 Neisseria meningitidis FAM18 nuclease YP_975983.1 2115381 R 272831 CDS YP_975984.1 121635739 4675282 complement(2116243..2118342) 1 NC_008767.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2118342 cysS 4675282 cysS Neisseria meningitidis FAM18 cysteinyl-tRNA synthetase YP_975984.1 2116243 R 272831 CDS YP_975985.1 121635740 4676019 complement(2118352..2119401) 1 NC_008767.1 ATP-binding protein 2119401 4676019 NMC2064 Neisseria meningitidis FAM18 ATP-binding protein YP_975985.1 2118352 R 272831 CDS YP_975986.1 121635741 4675547 complement(2119484..2120638) 1 NC_008767.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 2120638 obgE 4675547 obgE Neisseria meningitidis FAM18 GTPase ObgE YP_975986.1 2119484 R 272831 CDS YP_975987.1 121635742 4675548 2121196..2121549 1 NC_008767.1 cytochrome B561 2121549 cybB 4675548 cybB Neisseria meningitidis FAM18 cytochrome B561 YP_975987.1 2121196 D 272831 CDS YP_975988.1 121635743 4676310 complement(2121584..2122594) 1 NC_008767.1 hypothetical protein 2122594 4676310 NMC2068 Neisseria meningitidis FAM18 hypothetical protein YP_975988.1 2121584 R 272831 CDS YP_975989.1 121635744 4675677 2122506..2122853 1 NC_008767.1 hypothetical protein 2122853 4675677 NMC2069 Neisseria meningitidis FAM18 hypothetical protein YP_975989.1 2122506 D 272831 CDS YP_975990.1 121635745 4675678 2122858..2123451 1 NC_008767.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 2123451 gmhA 4675678 gmhA Neisseria meningitidis FAM18 phosphoheptose isomerase YP_975990.1 2122858 D 272831 CDS YP_975991.1 121635746 4676392 2123515..2124123 1 NC_008767.1 lipoprotein 2124123 4676392 NMC2071 Neisseria meningitidis FAM18 lipoprotein YP_975991.1 2123515 D 272831 CDS YP_975992.1 121635747 4675421 2124188..2124781 1 NC_008767.1 hypothetical protein 2124781 4675421 NMC2072 Neisseria meningitidis FAM18 hypothetical protein YP_975992.1 2124188 D 272831 CDS YP_975993.1 121635748 4675422 2124821..2125600 1 NC_008767.1 methionine aminopeptidase 2125600 map 4675422 map Neisseria meningitidis FAM18 methionine aminopeptidase YP_975993.1 2124821 D 272831 CDS YP_975994.1 121635749 4676324 2125755..2126054 1 NC_008767.1 hypothetical protein 2126054 4676324 NMC2074 Neisseria meningitidis FAM18 hypothetical protein YP_975994.1 2125755 D 272831 CDS YP_975995.1 121635750 4674862 2126106..2126666 1 NC_008767.1 adhesin 2126666 4674862 NMC2075 Neisseria meningitidis FAM18 adhesin YP_975995.1 2126106 D 272831 CDS YP_975996.1 121635751 4674863 complement(2126854..2128320) 1 NC_008767.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2128320 mqo 4674863 mqo Neisseria meningitidis FAM18 malate:quinone oxidoreductase YP_975996.1 2126854 R 272831 CDS YP_975997.1 121635752 4676287 complement(2128857..2129447) 1 NC_008767.1 hypothetical protein 2129447 4676287 NMC2077 Neisseria meningitidis FAM18 hypothetical protein YP_975997.1 2128857 R 272831 CDS YP_975998.1 121635753 4676101 complement(2129508..2130167) 1 NC_008767.1 hypothetical protein 2130167 4676101 NMC2078 Neisseria meningitidis FAM18 hypothetical protein YP_975998.1 2129508 R 272831 CDS YP_975999.1 121635754 4676102 2130167..2130376 1 NC_008767.1 hypothetical protein 2130376 4676102 NMC2079 Neisseria meningitidis FAM18 hypothetical protein YP_975999.1 2130167 D 272831 CDS YP_976000.1 121635755 4676362 2130577..2131305 1 NC_008767.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2131305 rpsB 4676362 rpsB Neisseria meningitidis FAM18 30S ribosomal protein S2 YP_976000.1 2130577 D 272831 CDS YP_976001.1 121635756 4675267 2131455..2132288 1 NC_008767.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2132288 tsf 4675267 tsf Neisseria meningitidis FAM18 elongation factor Ts YP_976001.1 2131455 D 272831 CDS YP_976002.1 121635757 4674754 2132505..2133224 1 NC_008767.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 2133224 pyrH 4674754 pyrH Neisseria meningitidis FAM18 uridylate kinase YP_976002.1 2132505 D 272831 CDS YP_976003.1 121635758 4675766 2133408..2134370 1 NC_008767.1 adhesin 2134370 mafA 4675766 mafA Neisseria meningitidis FAM18 adhesin YP_976003.1 2133408 D 272831 CDS YP_976004.1 121635759 4676326 2134410..2135792 1 NC_008767.1 adhesin 2135792 mafB 4676326 mafB Neisseria meningitidis FAM18 adhesin YP_976004.1 2134410 D 272831 CDS YP_976005.1 121635760 4675933 2135789..2136106 1 NC_008767.1 hypothetical protein 2136106 4675933 NMC2085 Neisseria meningitidis FAM18 hypothetical protein YP_976005.1 2135789 D 272831 CDS YP_976006.1 121635761 4675705 2136854..2137060 1 NC_008767.1 hypothetical protein 2137060 4675705 NMC2087 Neisseria meningitidis FAM18 hypothetical protein YP_976006.1 2136854 D 272831 CDS YP_976007.1 121635762 4675706 2137192..2137443 1 NC_008767.1 hypothetical protein 2137443 4675706 NMC2088 Neisseria meningitidis FAM18 hypothetical protein YP_976007.1 2137192 D 272831 CDS YP_976008.1 121635763 4675673 2137479..2137811 1 NC_008767.1 hypothetical protein 2137811 4675673 NMC2089 Neisseria meningitidis FAM18 hypothetical protein YP_976008.1 2137479 D 272831 CDS YP_976009.1 121635764 4675674 2138062..2139048 1 NC_008767.1 mafb protein (fragment) 2139048 4675674 NMC2090 Neisseria meningitidis FAM18 mafb protein (fragment) YP_976009.1 2138062 D 272831 CDS YP_976010.1 121635765 4675545 2139130..2139477 1 NC_008767.1 LOW G+C REGION; hypothetical protein 2139477 4675545 NMC2091 Neisseria meningitidis FAM18 hypothetical protein YP_976010.1 2139130 D 272831 CDS YP_976011.1 121635766 4675546 2139480..2139803 1 NC_008767.1 LOW G+C REGION; hypothetical protein 2139803 4675546 NMC2092 Neisseria meningitidis FAM18 hypothetical protein YP_976011.1 2139480 D 272831 CDS YP_976012.1 121635767 4675416 2139841..2140185 1 NC_008767.1 LOW G+C REGION; hypothetical protein 2140185 4675416 NMC2093 Neisseria meningitidis FAM18 hypothetical protein YP_976012.1 2139841 D 272831 CDS YP_976013.1 121635768 4675409 2140938..2141156 1 NC_008767.1 hypothetical protein 2141156 4675409 NMC2095 Neisseria meningitidis FAM18 hypothetical protein YP_976013.1 2140938 D 272831 CDS YP_976014.1 121635769 4675410 2141153..2141512 1 NC_008767.1 LOW G+C REGION; hypothetical protein 2141512 4675410 NMC2096 Neisseria meningitidis FAM18 hypothetical protein YP_976014.1 2141153 D 272831 CDS YP_976015.1 121635770 4675405 2141588..2141800 1 NC_008767.1 LOW G+C REGION; hypothetical protein 2141800 4675405 NMC2097 Neisseria meningitidis FAM18 hypothetical protein YP_976015.1 2141588 D 272831 CDS YP_976016.1 121635771 4675418 2142065..2142421 1 NC_008767.1 hypothetical protein 2142421 4675418 NMC2099 Neisseria meningitidis FAM18 hypothetical protein YP_976016.1 2142065 D 272831 CDS YP_976017.1 121635772 4675419 2142469..2142597 1 NC_008767.1 hypothetical protein 2142597 4675419 NMC2100 Neisseria meningitidis FAM18 hypothetical protein YP_976017.1 2142469 D 272831 CDS YP_976018.1 121635773 4675583 complement(2143926..2144912) 1 NC_008767.1 protease 2144912 4675583 NMC2103 Neisseria meningitidis FAM18 protease YP_976018.1 2143926 R 272831 CDS YP_976019.1 121635774 4675584 complement(2144952..2145752) 1 NC_008767.1 hypothetical protein 2145752 4675584 NMC2104 Neisseria meningitidis FAM18 hypothetical protein YP_976019.1 2144952 R 272831 CDS YP_976020.1 121635775 4675492 2145877..2147220 1 NC_008767.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 2147220 argG 4675492 argG Neisseria meningitidis FAM18 argininosuccinate synthase YP_976020.1 2145877 D 272831 CDS YP_976021.1 121635776 4675866 2147268..2147510 1 NC_008767.1 hypothetical protein 2147510 4675866 NMC2107 Neisseria meningitidis FAM18 hypothetical protein YP_976021.1 2147268 D 272831 CDS YP_976022.1 121635777 4675493 2147503..2147718 1 NC_008767.1 hypothetical protein 2147718 4675493 NMC2108 Neisseria meningitidis FAM18 hypothetical protein YP_976022.1 2147503 D 272831 CDS YP_976023.1 121635778 4675485 complement(2147794..2149287) 1 NC_008767.1 hypothetical protein 2149287 4675485 NMC2109 Neisseria meningitidis FAM18 hypothetical protein YP_976023.1 2147794 R 272831 CDS YP_976024.1 121635779 4675486 complement(2149399..2150628) 1 NC_008767.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 2150628 4675486 NMC2110 Neisseria meningitidis FAM18 serine/threonine transporter SstT YP_976024.1 2149399 R 272831 CDS YP_976025.1 121635780 4675543 2151040..2152887 1 NC_008767.1 hypothetical protein 2152887 4675543 NMC2112 Neisseria meningitidis FAM18 hypothetical protein YP_976025.1 2151040 D 272831 CDS YP_976026.1 121635781 4675544 2152942..2157111 1 NC_008767.1 hypothetical protein 2157111 4675544 NMC2113 Neisseria meningitidis FAM18 hypothetical protein YP_976026.1 2152942 D 272831 CDS YP_976027.1 121635782 4676571 2158083..2159540 1 NC_008767.1 peptide transporter 2159540 4676571 NMC2114 Neisseria meningitidis FAM18 peptide transporter YP_976027.1 2158083 D 272831 CDS YP_976028.1 121635783 4676572 complement(2160450..2161553) 1 NC_008767.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 2161553 prfB 4676572 prfB Neisseria meningitidis FAM18 peptide chain release factor 2 YP_976028.1 2160450 R 272831 CDS YP_976029.1 121635784 4676067 complement(2161656..2162558) 1 NC_008767.1 lipoprotein 2162558 4676067 NMC2118 Neisseria meningitidis FAM18 lipoprotein YP_976029.1 2161656 R 272831 CDS YP_976030.1 121635785 4675240 2162891..2163340 1 NC_008767.1 hypothetical protein 2163340 4675240 NMC2119 Neisseria meningitidis FAM18 hypothetical protein YP_976030.1 2162891 D 272831 CDS YP_976031.1 121635786 4675241 2163414..2163722 1 NC_008767.1 hypothetical protein 2163722 4675241 NMC2120 Neisseria meningitidis FAM18 hypothetical protein YP_976031.1 2163414 D 272831 CDS YP_976032.1 121635787 4675254 2163814..2164680 1 NC_008767.1 hypothetical protein 2164680 4675254 NMC2121 Neisseria meningitidis FAM18 hypothetical protein YP_976032.1 2163814 D 272831 CDS YP_976033.1 121635788 4675255 2164649..2165416 1 NC_008767.1 hypothetical protein 2165416 4675255 NMC2122 Neisseria meningitidis FAM18 hypothetical protein YP_976033.1 2164649 D 272831 CDS YP_976034.1 121635789 4675350 2165438..2166025 1 NC_008767.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 2166025 4675350 NMC2123 Neisseria meningitidis FAM18 RNA polymerase sigma factor YP_976034.1 2165438 D 272831 CDS YP_976035.1 121635790 4675351 2166442..2166882 1 NC_008767.1 lipoprotein 2166882 4675351 NMC2124 Neisseria meningitidis FAM18 lipoprotein YP_976035.1 2166442 D 272831 CDS YP_976036.1 121635791 4675343 2167356..2168321 1 NC_008767.1 insertion element IS1655 transposase 2168321 4675343 NMC2125 Neisseria meningitidis FAM18 insertion element IS1655 transposase YP_976036.1 2167356 D 272831 CDS YP_976037.1 121635792 4675344 2168865..2169518 1 NC_008767.1 insertion element IS1016 transposase 2169518 4675344 NMC2126 Neisseria meningitidis FAM18 insertion element IS1016 transposase YP_976037.1 2168865 D 272831 CDS YP_976038.1 121635793 4676218 complement(2169590..2170192) 1 NC_008767.1 hypothetical protein 2170192 4676218 NMC2128 Neisseria meningitidis FAM18 hypothetical protein YP_976038.1 2169590 R 272831 CDS YP_976039.1 121635794 4676219 complement(2170226..2171497) 1 NC_008767.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 2171497 purD 4676219 purD Neisseria meningitidis FAM18 phosphoribosylamine--glycine ligase YP_976039.1 2170226 R 272831 CDS YP_976040.1 121635795 4676024 2171655..2171972 1 NC_008767.1 hypothetical protein 2171972 4676024 NMC2130 Neisseria meningitidis FAM18 hypothetical protein YP_976040.1 2171655 D 272831 CDS YP_976041.1 121635796 4676256 complement(2172024..2172635) 1 NC_008767.1 hypothetical protein 2172635 4676256 NMC2131 Neisseria meningitidis FAM18 hypothetical protein YP_976041.1 2172024 R 272831 CDS YP_976042.1 121635797 4676257 complement(2172698..2173633) 1 NC_008767.1 electron transfer flavoprotein subunit alpha 2173633 etfA 4676257 etfA Neisseria meningitidis FAM18 electron transfer flavoprotein subunit alpha YP_976042.1 2172698 R 272831 CDS YP_976043.1 121635798 4675890 complement(2173644..2174393) 1 NC_008767.1 electron transfer flavoprotein subunit beta 2174393 etfB 4675890 etfB Neisseria meningitidis FAM18 electron transfer flavoprotein subunit beta YP_976043.1 2173644 R 272831 CDS YP_976044.1 121635799 4675897 complement(2174619..2175587) 1 NC_008767.1 lipopolysaccharide heptosyltransferase I 2175587 4675897 NMC2134 Neisseria meningitidis FAM18 lipopolysaccharide heptosyltransferase I YP_976044.1 2174619 R 272831 CDS YP_976045.1 121635800 4676307 complement(2175625..2176260) 1 NC_008767.1 nicotinamidase 2176260 pncA 4676307 pncA Neisseria meningitidis FAM18 nicotinamidase YP_976045.1 2175625 R 272831 CDS YP_976046.1 121635801 4676108 2176375..2177055 1 NC_008767.1 hypothetical protein 2177055 4676108 NMC2136 Neisseria meningitidis FAM18 hypothetical protein YP_976046.1 2176375 D 272831 CDS YP_976047.1 121635802 4676308 complement(2177313..2178350) 1 NC_008767.1 glyceraldehyde 3-phosphate dehydrogenase C 2178350 4676308 NMC2137 Neisseria meningitidis FAM18 glyceraldehyde 3-phosphate dehydrogenase C YP_976047.1 2177313 R 272831 CDS YP_976048.1 121635803 4676244 2178761..2181355 1 NC_008767.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2181355 mutS 4676244 mutS Neisseria meningitidis FAM18 DNA mismatch repair protein MutS YP_976048.1 2178761 D 272831 CDS YP_976049.1 121635804 4676214 complement(2181478..2181969) 1 NC_008767.1 acetyltransferase 2181969 4676214 NMC2139 Neisseria meningitidis FAM18 acetyltransferase YP_976049.1 2181478 R 272831 CDS YP_976050.1 121635805 4676245 complement(2181973..2182371) 1 NC_008767.1 hypothetical protein 2182371 4676245 NMC2140 Neisseria meningitidis FAM18 hypothetical protein YP_976050.1 2181973 R 272831 CDS YP_976051.1 121635806 4676258 complement(2182389..2183783) 1 NC_008767.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2183783 gltX 4676258 gltX Neisseria meningitidis FAM18 glutamyl-tRNA synthetase YP_976051.1 2182389 R 272831 CDS YP_976052.1 121635807 4676574 complement(2183899..2184555) 1 NC_008767.1 hypothetical protein 2184555 4676574 NMC2142 Neisseria meningitidis FAM18 hypothetical protein YP_976052.1 2183899 R 272831 CDS YP_976053.1 121635808 4676259 complement(2184552..2184905) 1 NC_008767.1 oxidoreductase 2184905 4676259 NMC2143 Neisseria meningitidis FAM18 oxidoreductase YP_976053.1 2184552 R 272831 CDS YP_976054.1 121635809 4676265 2185029..2185511 1 NC_008767.1 periplasmic thiredoxin 2185511 4676265 NMC2144 Neisseria meningitidis FAM18 periplasmic thiredoxin YP_976054.1 2185029 D 272831 CDS YP_976055.1 121635810 4676266 2185705..2186355 1 NC_008767.1 ABC transporter ATP-binding protein 2186355 ftsE 4676266 ftsE Neisseria meningitidis FAM18 ABC transporter ATP-binding protein YP_976055.1 2185705 D 272831 CDS YP_976056.1 121635811 4676657 2186352..2187269 1 NC_008767.1 ABC transporter integral membrane protein 2187269 ftsX 4676657 ftsX Neisseria meningitidis FAM18 ABC transporter integral membrane protein YP_976056.1 2186352 D 272831 CDS YP_976057.1 121635812 4676665 2187330..2187608 1 NC_008767.1 hypothetical protein 2187608 4676665 NMC2147 Neisseria meningitidis FAM18 hypothetical protein YP_976057.1 2187330 D 272831 CDS YP_976058.1 121635813 4676170 complement(2187675..2188853) 1 NC_008767.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 2188853 pgk 4676170 pgk Neisseria meningitidis FAM18 phosphoglycerate kinase YP_976058.1 2187675 R 272831 CDS YP_976059.1 121635814 4676143 complement(2188934..2190187) 1 NC_008767.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2190187 murA 4676143 murA Neisseria meningitidis FAM18 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_976059.1 2188934 R 272831 CDS YP_976060.1 121635815 4676267 complement(2190551..2191525) 1 NC_008767.1 transmembrane transport protein 2191525 4676267 NMC2150 Neisseria meningitidis FAM18 transmembrane transport protein YP_976060.1 2190551 R 272831 CDS YP_976061.1 121635816 4676171 complement(2191558..2192019) 1 NC_008767.1 hypothetical protein 2192019 4676171 NMC2151 Neisseria meningitidis FAM18 hypothetical protein YP_976061.1 2191558 R 272831 CDS YP_976062.1 121635817 4676293 complement(2192048..2193385) 1 NC_008767.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 2193385 kdtA 4676293 kdtA Neisseria meningitidis FAM18 3-deoxy-D-manno-octulosonic-acid transferase YP_976062.1 2192048 R 272831 CDS YP_976063.1 121635818 4676406 complement(2193382..2194830) 1 NC_008767.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2194830 gnd 4676406 gnd Neisseria meningitidis FAM18 6-phosphogluconate dehydrogenase YP_976063.1 2193382 R 272831 CDS