-- dump date 20140619_163346 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 272831000001 SEQ_END SEQ_END NC_008767.1 2194961 2194961 DR NC_008767.1; contig end 2194961..2194961 Neisseria meningitidis FAM18 YP_974147.1 CDS lpxC NC_008767.1 1261 2184 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(1261..2184) Neisseria meningitidis FAM18 4675238 YP_974148.1 CDS pilS2 NC_008767.1 3675 4040 R truncated pilin complement(3675..4040) Neisseria meningitidis FAM18 4675991 YP_974149.1 CDS fbp NC_008767.1 4069 4398 R peptidyl-prolyl cis-trans isomerase complement(4069..4398) Neisseria meningitidis FAM18 4675992 YP_974150.1 CDS NMC0005 NC_008767.1 4476 4694 R hypothetical protein complement(4476..4694) Neisseria meningitidis FAM18 4675837 YP_974151.1 CDS NMC0006 NC_008767.1 4816 5769 D glycerate dehydrogenase 4816..5769 Neisseria meningitidis FAM18 4675117 YP_974152.1 CDS metG NC_008767.1 5843 7900 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(5843..7900) Neisseria meningitidis FAM18 4675118 YP_974153.1 CDS glmS NC_008767.1 8016 9854 R isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(8016..9854) Neisseria meningitidis FAM18 4676318 YP_974154.1 CDS NMC0009 NC_008767.1 10290 10808 D lipoprotein 10290..10808 Neisseria meningitidis FAM18 4676509 YP_974155.1 CDS gna33 NC_008767.1 11226 12551 R outer membrane lipoprotein Gna33; membrane-bound lytic murein transglycosylase complement(11226..12551) Neisseria meningitidis FAM18 4675112 YP_974156.1 CDS NMC0011 NC_008767.1 12763 13602 D hypothetical protein 12763..13602 Neisseria meningitidis FAM18 4676527 YP_974157.1 CDS NMC0012 NC_008767.1 13599 14765 D hypothetical protein 13599..14765 Neisseria meningitidis FAM18 4675114 YP_974158.1 CDS NMC0013 NC_008767.1 15029 16294 D hypothetical protein 15029..16294 Neisseria meningitidis FAM18 4675116 YP_974159.1 CDS phnA NC_008767.1 16366 16695 R phosphonoacetate hydrolase complement(16366..16695) Neisseria meningitidis FAM18 4675108 YP_974160.1 CDS glmU NC_008767.1 16772 18142 R UDP-N-acetylglucosamine pyrophosphorylase complement(16772..18142) Neisseria meningitidis FAM18 4676123 YP_974161.1 CDS NMC0016 NC_008767.1 18197 19174 R May be two merged CDSs or a complete CDS which has a frameshift mutation in Neisseria meningitidis serogroup A strain Z2491 at a homopolymeric run. N-terminal region similar and equivalent to Neisseria meningitidis possible hydrolase NMA0286 SWALL:Q9JWN1 (EMBL:AL162752) (243 aa) fasta scores: E(): 1.1e-86, 94.78% id in 230 aa. C-terminal region similar and equivalent to Neisseria meningitidis lipoprotein NMA0285 SWALL:Q9JWN2 (EMBL:AL162752) (90 aa) fasta scores: E(): 4.5e-28, 87.77% id in 90 aa.; hypothetical protein complement(18197..19174) Neisseria meningitidis FAM18 4676510 YP_974162.1 CDS tbpA NC_008767.1 19233 20234 D solute-binding periplasmic protein 19233..20234 Neisseria meningitidis FAM18 4675111 YP_974163.1 CDS NMC0018 NC_008767.1 20328 21176 D hypothetical protein 20328..21176 Neisseria meningitidis FAM18 4675208 YP_974164.1 CDS NMC0019 NC_008767.1 21203 21688 D hypothetical protein 21203..21688 Neisseria meningitidis FAM18 4675113 YP_974165.1 CDS pilB NC_008767.1 21790 23358 R trifunctional thioredoxin/methionine sulfoxide reductase A/B protein complement(21790..23358) Neisseria meningitidis FAM18 4675107 YP_974166.1 CDS pilA NC_008767.1 23503 24768 D signal recognition particle protein 23503..24768 Neisseria meningitidis FAM18 4676126 YP_974167.1 CDS NMC0022 NC_008767.1 25628 26584 R transposase complement(25628..26584) Neisseria meningitidis FAM18 4676119 YP_974168.1 CDS NMC0023 NC_008767.1 26799 27986 R hypothetical protein complement(26799..27986) Neisseria meningitidis FAM18 4675105 YP_974169.1 CDS NMC0024 NC_008767.1 27987 28271 R hypothetical protein complement(27987..28271) Neisseria meningitidis FAM18 4675106 YP_974170.1 CDS NMC0025 NC_008767.1 28574 30133 R TspB protein complement(28574..30133) Neisseria meningitidis FAM18 4675099 YP_974171.1 CDS NMC0027 NC_008767.1 30552 30854 R hypothetical protein complement(30552..30854) Neisseria meningitidis FAM18 4675104 YP_974172.1 CDS NMC0028 NC_008767.1 30882 31112 R hypothetical protein complement(30882..31112) Neisseria meningitidis FAM18 4675098 YP_974173.1 CDS NMC0029 NC_008767.1 31339 31539 R hypothetical protein complement(31339..31539) Neisseria meningitidis FAM18 4675091 YP_974174.1 CDS NMC0030 NC_008767.1 31543 31854 R hypothetical protein complement(31543..31854) Neisseria meningitidis FAM18 4675096 YP_974175.1 CDS NMC0031 NC_008767.1 31875 33083 R hypothetical protein complement(31875..33083) Neisseria meningitidis FAM18 4675097 YP_974176.1 CDS pilC NC_008767.1 34401 37547 D pilus assembly protein PilC 34401..37547 Neisseria meningitidis FAM18 4675089 YP_974177.1 CDS NMC0034 NC_008767.1 38697 40847 R hypothetical protein complement(38697..40847) Neisseria meningitidis FAM18 4676127 YP_974178.1 CDS pilU NC_008767.1 41133 42359 R twitching motility protein PilT complement(41133..42359) Neisseria meningitidis FAM18 4675090 YP_974179.1 CDS pilT NC_008767.1 42522 43565 R pilus retraction protein complement(42522..43565) Neisseria meningitidis FAM18 4676088 YP_974180.1 CDS NMC0037 NC_008767.1 43685 44371 D hypothetical protein 43685..44371 Neisseria meningitidis FAM18 4676031 YP_974181.1 CDS NMC0038 NC_008767.1 44371 44778 D lipoprotein 44371..44778 Neisseria meningitidis FAM18 4675085 YP_974182.1 CDS proC NC_008767.1 44827 45618 D pyrroline-5-carboxylate reductase 44827..45618 Neisseria meningitidis FAM18 4675086 YP_974183.1 CDS dksA NC_008767.1 45765 46181 D DnaK suppressor protein 45765..46181 Neisseria meningitidis FAM18 4675872 YP_974184.1 CDS NMC0041 NC_008767.1 51981 52445 D DNA transport competence protein 51981..52445 Neisseria meningitidis FAM18 4675959 YP_974185.1 CDS NMC0042 NC_008767.1 52506 52667 R hypothetical protein complement(52506..52667) Neisseria meningitidis FAM18 4675087 YP_974186.1 CDS dnaJ NC_008767.1 52714 53835 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 52714..53835 Neisseria meningitidis FAM18 4675088 YP_974187.1 CDS NMC0044 NC_008767.1 54031 56049 D inner membrane transport protein 54031..56049 Neisseria meningitidis FAM18 4675943 YP_974188.1 CDS rfbC NC_008767.1 56093 56665 R dTDP-4-dehydrorhamnose 3,5-epimerase complement(56093..56665) Neisseria meningitidis FAM18 4675081 YP_974189.1 CDS rfbA NC_008767.1 56704 57570 R glucose-1-phosphate thymidylyltransferase complement(56704..57570) Neisseria meningitidis FAM18 4675611 YP_974190.1 CDS rfbB NC_008767.1 57633 58700 R dTDP-glucose 4,6-dehydratase complement(57633..58700) Neisseria meningitidis FAM18 4675560 YP_974191.1 CDS galE NC_008767.1 58816 59835 R UDP-glucose 4-epimerase complement(58816..59835) Neisseria meningitidis FAM18 4675614 YP_974192.1 CDS NMC0050 NC_008767.1 61225 62607 R hypothetical protein complement(61225..62607) Neisseria meningitidis FAM18 4675084 YP_974193.1 CDS NMC0051 NC_008767.1 62636 64114 R alpha-2,9-polysialyltransferase complement(62636..64114) Neisseria meningitidis FAM18 4675075 YP_974194.1 CDS siaC NC_008767.1 64194 65243 R N-acetylneuraminic acid synthase complement(64194..65243) Neisseria meningitidis FAM18 4675073 YP_974195.1 CDS siaB NC_008767.1 65244 65930 R acylneuraminate cytidylyltransferase complement(65244..65930) Neisseria meningitidis FAM18 4675072 YP_974196.1 CDS sacA NC_008767.1 65934 67067 R N-acetylglucosamine-6-phosphate 2-epimerase complement(65934..67067) Neisseria meningitidis FAM18 4675083 YP_974197.1 CDS ctrA NC_008767.1 67202 68377 D capsule polysaccharide export outer membrane protein 67202..68377 Neisseria meningitidis FAM18 4675121 YP_974198.1 CDS ctrB NC_008767.1 68392 69555 D capsule polysaccharide export inner-membrane protein 68392..69555 Neisseria meningitidis FAM18 4676616 YP_974199.1 CDS ctrC NC_008767.1 69555 70352 D capsule polysaccharide export inner-membrane protein 69555..70352 Neisseria meningitidis FAM18 4676269 YP_974200.1 CDS ctrD NC_008767.1 70349 70999 D capsule polysaccharide export ATP-binding protein CtrD 70349..70999 Neisseria meningitidis FAM18 4676270 YP_974201.1 CDS NMC0059 NC_008767.1 71060 73336 D transcriptional accessory protein 71060..73336 Neisseria meningitidis FAM18 4676309 YP_974202.1 CDS rfbB2 NC_008767.1 75521 76588 D dTDP-glucose 4,6-dehydratase 75521..76588 Neisseria meningitidis FAM18 4675070 YP_974203.1 CDS rfbA2 NC_008767.1 76651 77517 D glucose-1-phosphate thymidylyltransferase 76651..77517 Neisseria meningitidis FAM18 4675610 YP_974204.1 CDS rfbC2 NC_008767.1 77556 78110 D dTDP-D-glucose 4,6-dehydratase 77556..78110 Neisseria meningitidis FAM18 4675613 YP_974205.1 CDS lipA NC_008767.1 78134 80248 D capsule polysaccharide modification protein 78134..80248 Neisseria meningitidis FAM18 4675541 YP_974206.1 CDS lipB NC_008767.1 80385 81644 D capsule polysaccharide modification protein 80385..81644 Neisseria meningitidis FAM18 4676394 YP_974207.1 CDS NMC0068 NC_008767.1 82013 83419 D hypothetical protein 82013..83419 Neisseria meningitidis FAM18 4676378 YP_974208.1 CDS gltS NC_008767.1 83637 84851 D sodium/glutamate symport carrier protein 83637..84851 Neisseria meningitidis FAM18 4675068 YP_974209.1 CDS NMC0071 NC_008767.1 84950 85966 D lipoprotein 84950..85966 Neisseria meningitidis FAM18 4676577 YP_974210.1 CDS NMC0072 NC_008767.1 85977 86174 D hypothetical protein 85977..86174 Neisseria meningitidis FAM18 4675064 YP_974211.1 CDS NMC0073 NC_008767.1 86600 88000 R outer membrane transport protein complement(86600..88000) Neisseria meningitidis FAM18 4675067 YP_974212.1 CDS pykA NC_008767.1 88308 89780 R pyruvate kinase complement(88308..89780) Neisseria meningitidis FAM18 4675060 YP_974213.1 CDS NMC0075 NC_008767.1 90041 90370 D IS1016 transposase, partial CDS 90041..90370 Neisseria meningitidis FAM18 4675783 YP_974214.1 CDS NMC0080 NC_008767.1 91332 91568 D hypothetical protein 91332..91568 Neisseria meningitidis FAM18 4675063 YP_974215.1 CDS NMC0081 NC_008767.1 91562 91789 D hypothetical protein 91562..91789 Neisseria meningitidis FAM18 4675056 YP_974216.1 CDS NMC0083 NC_008767.1 92161 92349 D hypothetical protein 92161..92349 Neisseria meningitidis FAM18 4675059 YP_974217.1 CDS NMC0083A NC_008767.1 92356 92508 D hypothetical protein 92356..92508 Neisseria meningitidis FAM18 4675055 YP_974218.1 CDS NMC0084 NC_008767.1 92609 92746 D hypothetical protein 92609..92746 Neisseria meningitidis FAM18 4675057 YP_974219.1 CDS NMC0085 NC_008767.1 92791 94056 D protein export protein 92791..94056 Neisseria meningitidis FAM18 4675052 YP_974220.1 CDS NMC0086 NC_008767.1 94059 96146 D protein export protein 94059..96146 Neisseria meningitidis FAM18 4675053 YP_974221.1 CDS NMC0088 NC_008767.1 96416 97423 D IS1106 transposase 96416..97423 Neisseria meningitidis FAM18 4675049 YP_974222.1 CDS NMC0089 NC_008767.1 97605 97751 R hypothetical protein complement(97605..97751) Neisseria meningitidis FAM18 4675050 YP_974223.1 CDS NMC0092 NC_008767.1 98556 99107 D hypothetical protein 98556..99107 Neisseria meningitidis FAM18 4675044 YP_974224.1 CDS NMC0093 NC_008767.1 99384 100043 R periplasmic peptidase (bacteriocin resistance) complement(99384..100043) Neisseria meningitidis FAM18 4675046 YP_974225.1 CDS NMC0094 NC_008767.1 100024 100260 R hypothetical protein complement(100024..100260) Neisseria meningitidis FAM18 4675043 YP_974226.1 CDS NMC0095 NC_008767.1 100382 101057 R hypothetical protein complement(join(100382..100981,100983..101057)) Neisseria meningitidis FAM18 4675045 YP_974227.1 CDS NMC0096 NC_008767.1 101184 101342 R lipoprotein complement(101184..101342) Neisseria meningitidis FAM18 4675040 YP_974228.1 CDS NMC0097 NC_008767.1 101339 102181 R hypothetical protein complement(101339..102181) Neisseria meningitidis FAM18 4675042 YP_974229.1 CDS pyrB NC_008767.1 102420 103340 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 102420..103340 Neisseria meningitidis FAM18 4675038 YP_974230.1 CDS pyrI NC_008767.1 103350 103808 D involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 103350..103808 Neisseria meningitidis FAM18 4675790 YP_974231.1 CDS NMC0100 NC_008767.1 103873 104538 D hypothetical protein 103873..104538 Neisseria meningitidis FAM18 4675767 YP_974232.1 CDS NMC0101 NC_008767.1 104601 105818 R hypothetical protein complement(104601..105818) Neisseria meningitidis FAM18 4675039 YP_974233.1 CDS def NC_008767.1 106002 106505 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 106002..106505 Neisseria meningitidis FAM18 4675035 YP_974234.1 CDS fmt NC_008767.1 106592 107518 D methionyl-tRNA formyltransferase 106592..107518 Neisseria meningitidis FAM18 4675967 YP_974235.1 CDS NMC0104 NC_008767.1 107597 108856 D SUN-family protein 107597..108856 Neisseria meningitidis FAM18 4676701 YP_974236.1 CDS NMC0105 NC_008767.1 108822 109421 D hypothetical protein 108822..109421 Neisseria meningitidis FAM18 4675037 YP_974237.1 CDS NMC0106 NC_008767.1 109421 111538 D two-component sensor kinase 109421..111538 Neisseria meningitidis FAM18 4675033 YP_974238.1 CDS NMC0107 NC_008767.1 111531 112808 D two-component transcriptional regulator 111531..112808 Neisseria meningitidis FAM18 4675034 YP_974239.1 CDS smf NC_008767.1 112899 114092 D SMF-family protein 112899..114092 Neisseria meningitidis FAM18 4675036 YP_974240.1 CDS NMC0109 NC_008767.1 114118 114579 D SMG-family protein 114118..114579 Neisseria meningitidis FAM18 4675062 YP_974241.1 CDS topA NC_008767.1 114651 116957 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I 114651..116957 Neisseria meningitidis FAM18 4675032 YP_974242.1 CDS NMC0111 NC_008767.1 117030 117725 R hypothetical protein complement(117030..117725) Neisseria meningitidis FAM18 4674852 YP_974243.1 CDS NMC0112 NC_008767.1 117745 118297 R hypothetical protein complement(join(117745..117978,117980..118297)) Neisseria meningitidis FAM18 4675024 YP_974244.1 CDS NMC0113 NC_008767.1 118416 118793 D hypothetical protein 118416..118793 Neisseria meningitidis FAM18 4675028 YP_974245.1 CDS NMC0114 NC_008767.1 118882 119451 D hypothetical protein 118882..119451 Neisseria meningitidis FAM18 4675029 YP_974246.1 CDS NMC0115 NC_008767.1 119574 119825 D ferredoxin 119574..119825 Neisseria meningitidis FAM18 4675019 YP_974247.1 CDS NMC0116 NC_008767.1 120242 121426 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 120242..121426 Neisseria meningitidis FAM18 4675020 YP_974248.1 CDS secE NC_008767.1 121623 121901 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 121623..121901 Neisseria meningitidis FAM18 4675021 YP_974249.1 CDS nusG NC_008767.1 121903 122439 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 121903..122439 Neisseria meningitidis FAM18 4675214 YP_974250.1 CDS rplK NC_008767.1 122540 122974 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 122540..122974 Neisseria meningitidis FAM18 4676186 YP_974251.1 CDS rplA NC_008767.1 122974 123669 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 122974..123669 Neisseria meningitidis FAM18 4675465 YP_974252.1 CDS rplJ NC_008767.1 123899 124399 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 123899..124399 Neisseria meningitidis FAM18 4675403 YP_974253.1 CDS rplL NC_008767.1 124457 124828 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 124457..124828 Neisseria meningitidis FAM18 4675464 YP_974254.1 CDS rpoB NC_008767.1 125013 129197 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 125013..129197 Neisseria meningitidis FAM18 4675468 YP_974255.1 CDS rpoC NC_008767.1 129354 133529 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 129354..133529 Neisseria meningitidis FAM18 4675257 YP_974256.1 CDS rpsL NC_008767.1 133787 134158 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 133787..134158 Neisseria meningitidis FAM18 4675272 YP_974257.1 CDS rpsG NC_008767.1 134276 134746 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 134276..134746 Neisseria meningitidis FAM18 4675230 YP_974258.1 CDS fusA NC_008767.1 134765 136870 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 134765..136870 Neisseria meningitidis FAM18 4675301 YP_974259.1 CDS NMC0128 NC_008767.1 136958 138142 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 136958..138142 Neisseria meningitidis FAM18 4676668 YP_974260.1 CDS rpsJ NC_008767.1 138160 138471 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 138160..138471 Neisseria meningitidis FAM18 4675022 YP_974261.1 CDS rplC NC_008767.1 139475 140119 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 139475..140119 Neisseria meningitidis FAM18 4675016 YP_974262.1 CDS rplD NC_008767.1 140119 140739 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 140119..140739 Neisseria meningitidis FAM18 4675473 YP_974263.1 CDS rplW NC_008767.1 140730 141050 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 140730..141050 Neisseria meningitidis FAM18 4675399 YP_974264.1 CDS rplB NC_008767.1 141056 141889 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 141056..141889 Neisseria meningitidis FAM18 4675442 YP_974265.1 CDS rpsS NC_008767.1 141896 142174 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 141896..142174 Neisseria meningitidis FAM18 4675472 YP_974266.1 CDS rplV NC_008767.1 142183 142512 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 142183..142512 Neisseria meningitidis FAM18 4675128 YP_974267.1 CDS rpsC NC_008767.1 142522 143214 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 142522..143214 Neisseria meningitidis FAM18 4675441 YP_974268.1 CDS rplP NC_008767.1 143198 143614 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 143198..143614 Neisseria meningitidis FAM18 4675246 YP_974269.1 CDS rpmC NC_008767.1 143614 143805 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 143614..143805 Neisseria meningitidis FAM18 4675384 YP_974270.1 CDS rpsQ NC_008767.1 143805 144068 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 143805..144068 Neisseria meningitidis FAM18 4675438 YP_974271.1 CDS rplN NC_008767.1 144290 144658 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 144290..144658 Neisseria meningitidis FAM18 4675218 YP_974272.1 CDS rplX NC_008767.1 144670 144993 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 144670..144993 Neisseria meningitidis FAM18 4675387 YP_974273.1 CDS rplE NC_008767.1 145003 145542 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 145003..145542 Neisseria meningitidis FAM18 4675439 YP_974274.1 CDS rpsN NC_008767.1 145545 145850 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 145545..145850 Neisseria meningitidis FAM18 4675400 YP_974275.1 CDS rpsH NC_008767.1 145866 146258 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 145866..146258 Neisseria meningitidis FAM18 4675228 YP_974276.1 CDS rplF NC_008767.1 146272 146805 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 146272..146805 Neisseria meningitidis FAM18 4675302 YP_974277.1 CDS rplR NC_008767.1 146819 147172 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 146819..147172 Neisseria meningitidis FAM18 4675462 YP_974278.1 CDS rpsE NC_008767.1 147191 147709 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 147191..147709 Neisseria meningitidis FAM18 4675381 YP_974279.1 CDS rpmD NC_008767.1 147702 147887 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 147702..147887 Neisseria meningitidis FAM18 4675303 YP_974280.1 CDS rplO NC_008767.1 147889 148323 D late assembly protein; 50S ribosomal protein L15 147889..148323 Neisseria meningitidis FAM18 4675433 YP_974281.1 CDS secY NC_008767.1 148335 149645 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 148335..149645 Neisseria meningitidis FAM18 4675388 YP_974282.1 CDS infA NC_008767.1 149650 149868 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 149650..149868 Neisseria meningitidis FAM18 4675095 YP_974283.1 CDS rpmJ NC_008767.1 149889 150002 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 149889..150002 Neisseria meningitidis FAM18 4675971 YP_974284.1 CDS rpsM NC_008767.1 150068 150430 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 150068..150430 Neisseria meningitidis FAM18 4675328 YP_974285.1 CDS rpsK NC_008767.1 150450 150845 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 150450..150845 Neisseria meningitidis FAM18 4675227 YP_974286.1 CDS rpsD NC_008767.1 150865 151485 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 150865..151485 Neisseria meningitidis FAM18 4675229 YP_974287.1 CDS rpoA NC_008767.1 151511 152497 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 151511..152497 Neisseria meningitidis FAM18 4675247 YP_974288.1 CDS rplQ NC_008767.1 152521 152889 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 152521..152889 Neisseria meningitidis FAM18 4675256 YP_974289.1 CDS minC NC_008767.1 153036 153749 D blocks the formation of polar Z-ring septums; septum formation inhibitor 153036..153749 Neisseria meningitidis FAM18 4675385 YP_974290.1 CDS minD NC_008767.1 153777 154592 D septum site-determining protein 153777..154592 Neisseria meningitidis FAM18 4676306 YP_974291.1 CDS minE NC_008767.1 154596 154859 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 154596..154859 Neisseria meningitidis FAM18 4676299 YP_974292.1 CDS oxyR NC_008767.1 154863 155783 D hydrogen peroxide-inducible genes activator 154863..155783 Neisseria meningitidis FAM18 4676300 YP_974293.1 CDS valS NC_008767.1 156113 158950 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(156113..158950) Neisseria meningitidis FAM18 4676121 YP_974294.1 CDS NMC0165 NC_008767.1 159047 159856 R zinc transporter ZupT complement(159047..159856) Neisseria meningitidis FAM18 4676713 YP_974295.1 CDS dadA NC_008767.1 160037 161293 R catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit complement(160037..161293) Neisseria meningitidis FAM18 4675017 YP_974296.1 CDS NMC0167 NC_008767.1 161372 162763 R amino-acid transporter complement(161372..162763) Neisseria meningitidis FAM18 4675996 YP_974297.1 CDS lpxA NC_008767.1 163121 163897 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(163121..163897) Neisseria meningitidis FAM18 4675015 YP_974298.1 CDS NMC0169 NC_008767.1 163940 164662 R hypothetical protein complement(163940..164662) Neisseria meningitidis FAM18 4676335 YP_974299.1 CDS fabZ NC_008767.1 164827 165276 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(164827..165276) Neisseria meningitidis FAM18 4675013 YP_974300.1 CDS lpxD NC_008767.1 165310 166356 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(165310..166356) Neisseria meningitidis FAM18 4675842 YP_974301.1 CDS NMC0172 NC_008767.1 166389 166889 R hypothetical protein complement(166389..166889) Neisseria meningitidis FAM18 4676345 YP_974302.1 CDS omp85 NC_008767.1 166955 169348 R hypothetical protein complement(166955..169348) Neisseria meningitidis FAM18 4675012 YP_974303.1 CDS NMC0174 NC_008767.1 169405 170745 R inner membrane protease complement(169405..170745) Neisseria meningitidis FAM18 4676187 YP_974304.1 CDS dxr NC_008767.1 170780 172015 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(170780..172015) Neisseria meningitidis FAM18 4675014 YP_974305.1 CDS cdsA NC_008767.1 172020 172817 R phosphatidate cytidylyltransferase complement(172020..172817) Neisseria meningitidis FAM18 4675916 YP_974306.1 CDS uppS NC_008767.1 172821 173594 R undecaprenyl diphosphate synthase complement(172821..173594) Neisseria meningitidis FAM18 4676661 YP_974307.1 CDS frr NC_008767.1 173623 174180 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(173623..174180) Neisseria meningitidis FAM18 4676670 YP_974308.1 CDS NMC0179 NC_008767.1 174361 175488 R hypothetical protein complement(174361..175488) Neisseria meningitidis FAM18 4676607 YP_974309.1 CDS NMC0180 NC_008767.1 175739 176227 D hypothetical protein 175739..176227 Neisseria meningitidis FAM18 4675011 YP_974310.1 CDS gidB NC_008767.1 176323 176946 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 176323..176946 Neisseria meningitidis FAM18 4675010 YP_974311.1 CDS NMC0182 NC_008767.1 177045 177818 D hypothetical protein 177045..177818 Neisseria meningitidis FAM18 4676605 YP_974312.1 CDS rnhB NC_008767.1 178616 179200 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(178616..179200) Neisseria meningitidis FAM18 4675004 YP_974313.1 CDS gidA NC_008767.1 179268 181163 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(179268..181163) Neisseria meningitidis FAM18 4675575 YP_974314.1 CDS NMC0185 NC_008767.1 181438 182865 R inner membrane amino-acid transport protein complement(181438..182865) Neisseria meningitidis FAM18 4676622 YP_974315.1 CDS pdxA NC_008767.1 183025 184014 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 183025..184014 Neisseria meningitidis FAM18 4675005 YP_974316.1 CDS rne NC_008767.1 185095 187854 R ribonuclease E complement(185095..187854) Neisseria meningitidis FAM18 4676135 YP_974317.1 CDS rluC NC_008767.1 188347 189339 D ribosomal large subunit pseudouridine synthase C 188347..189339 Neisseria meningitidis FAM18 4675573 YP_974318.1 CDS lpxB NC_008767.1 189405 190559 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 189405..190559 Neisseria meningitidis FAM18 4675593 YP_974319.1 CDS NMC0193 NC_008767.1 190769 191158 R hypothetical protein complement(190769..191158) Neisseria meningitidis FAM18 4676344 YP_974320.1 CDS NMC0194 NC_008767.1 191492 191791 D hypothetical protein 191492..191791 Neisseria meningitidis FAM18 4675009 YP_974321.1 CDS dapB NC_008767.1 192055 192864 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(192055..192864) Neisseria meningitidis FAM18 4675006 YP_974322.1 CDS NMC0196 NC_008767.1 192874 193251 R outer membrane lipoprotein complement(192874..193251) Neisseria meningitidis FAM18 4675950 YP_974323.1 CDS fur NC_008767.1 193409 193912 D ferric uptake regulation protein 193409..193912 Neisseria meningitidis FAM18 4675003 YP_974324.1 CDS aat NC_008767.1 193982 194707 D leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 193982..194707 Neisseria meningitidis FAM18 4676648 YP_974325.1 CDS gapA NC_008767.1 194955 195986 R glyceraldehyde 3-phosphate dehydrogenase complement(194955..195986) Neisseria meningitidis FAM18 4676294 YP_974326.1 CDS NMC0200 NC_008767.1 196185 197024 R ferredoxin complement(196185..197024) Neisseria meningitidis FAM18 4676637 YP_974327.1 CDS NMC0201 NC_008767.1 197173 199149 D inner membrane transport protein 197173..199149 Neisseria meningitidis FAM18 4675001 YP_974328.1 CDS gyrB NC_008767.1 202007 204397 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(202007..204397) Neisseria meningitidis FAM18 4675216 YP_974329.1 CDS NMC0205 NC_008767.1 204553 205539 D hypothetical protein 204553..205539 Neisseria meningitidis FAM18 4676507 YP_974330.1 CDS prlC NC_008767.1 205627 207663 D oligopeptidase A 205627..207663 Neisseria meningitidis FAM18 4674999 YP_974331.1 CDS NMC0207 NC_008767.1 207939 208505 R hypothetical protein complement(207939..208505) Neisseria meningitidis FAM18 4676069 YP_974332.1 CDS NMC0209 NC_008767.1 208969 209469 R hypothetical protein complement(208969..209469) Neisseria meningitidis FAM18 4675000 YP_974333.1 CDS pilE NC_008767.1 209923 210369 R class II pilin PilE complement(209923..210369) Neisseria meningitidis FAM18 4674996 YP_974334.1 CDS katA NC_008767.1 211530 213044 R catalase complement(211530..213044) Neisseria meningitidis FAM18 4675955 YP_974335.1 CDS NMC0212 NC_008767.1 213393 214244 D RNA polymerase sigma factor 213393..214244 Neisseria meningitidis FAM18 4675903 YP_974336.1 CDS NMC0214 NC_008767.1 216671 217888 R inner membrane transport protein complement(216671..217888) Neisseria meningitidis FAM18 4676140 YP_974337.1 CDS NMC0215 NC_008767.1 218313 219269 D inner membrane transport protein 218313..219269 Neisseria meningitidis FAM18 4674992 YP_974338.1 CDS fabF NC_008767.1 219511 220758 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(219511..220758) Neisseria meningitidis FAM18 4674993 YP_974339.1 CDS acpP NC_008767.1 220914 221150 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(220914..221150) Neisseria meningitidis FAM18 4675839 YP_974340.1 CDS pyrD NC_008767.1 221382 222389 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 221382..222389 Neisseria meningitidis FAM18 4675348 YP_974341.1 CDS NMC0220 NC_008767.1 222723 223046 D hypothetical protein 222723..223046 Neisseria meningitidis FAM18 4675774 YP_974342.1 CDS NMC0221 NC_008767.1 223133 223414 D hypothetical protein 223133..223414 Neisseria meningitidis FAM18 4674991 YP_974343.1 CDS NMC0222 NC_008767.1 223467 223940 D hypothetical protein 223467..223940 Neisseria meningitidis FAM18 4674987 YP_974344.1 CDS NMC0223 NC_008767.1 224194 224529 D hypothetical protein 224194..224529 Neisseria meningitidis FAM18 4674989 YP_974345.1 CDS glnE NC_008767.1 224709 227399 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 224709..227399 Neisseria meningitidis FAM18 4674990 YP_974346.1 CDS NMC0225 NC_008767.1 227699 228391 R hypothetical protein complement(227699..228391) Neisseria meningitidis FAM18 4676610 YP_974347.1 CDS NMC0226 NC_008767.1 228499 229692 R inner membrane transport protein complement(228499..229692) Neisseria meningitidis FAM18 4674985 YP_974348.1 CDS NMC0227 NC_008767.1 229821 230558 R LamB/YcsF family protein complement(229821..230558) Neisseria meningitidis FAM18 4674986 YP_974349.1 CDS NMC0228 NC_008767.1 230545 231474 R hypothetical protein complement(230545..231474) Neisseria meningitidis FAM18 4674988 YP_974350.1 CDS NMC0229 NC_008767.1 231471 232118 R hypothetical protein complement(231471..232118) Neisseria meningitidis FAM18 4674982 YP_974351.1 CDS uvrD NC_008767.1 232302 234509 D DNA helicase II 232302..234509 Neisseria meningitidis FAM18 4674984 YP_974352.1 CDS NMC0231 NC_008767.1 234744 235283 D hypothetical protein 234744..235283 Neisseria meningitidis FAM18 4676602 YP_974353.1 CDS NMC0232 NC_008767.1 235473 235688 R hypothetical protein complement(235473..235688) Neisseria meningitidis FAM18 4674980 YP_974354.1 CDS NMC0233 NC_008767.1 235812 236171 R hypothetical protein complement(235812..236171) Neisseria meningitidis FAM18 4674981 YP_974355.1 CDS NMC0234 NC_008767.1 236224 236601 D May be truncated at the N-terminus. Similar to Neisseria meningitidis IS1016 transposase NMA0022 SWALL:Q9JX76 (EMBL:AL162752) (125 aa) fasta scores: E(): 2.3e-51, 100% id in 125 aa, and to Haemophilus influenzae insertion sequence IS1016 SWALL:Q48208 (EMBL:X58176) (164 aa) fasta scores: E(): 6.2e-15, 70.58% id in 68 aa; IS1016 transposase 236224..236601 Neisseria meningitidis FAM18 4674983 YP_974356.1 CDS NMC0235 NC_008767.1 236755 237420 D hypothetical protein 236755..237420 Neisseria meningitidis FAM18 4674979 YP_974357.1 CDS NMC0236 NC_008767.1 237401 238894 D hypothetical protein 237401..238894 Neisseria meningitidis FAM18 4674977 YP_974358.1 CDS nuoA NC_008767.1 239356 239712 D NADH dehydrogenase I subunit A 239356..239712 Neisseria meningitidis FAM18 4674976 YP_974359.1 CDS nuoB NC_008767.1 239703 240185 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 239703..240185 Neisseria meningitidis FAM18 4676201 YP_974360.1 CDS nuoC NC_008767.1 240198 240791 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 240198..240791 Neisseria meningitidis FAM18 4676202 YP_974361.1 CDS nuoD NC_008767.1 240781 242037 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 240781..242037 Neisseria meningitidis FAM18 4676206 YP_974362.1 CDS nuoE NC_008767.1 242037 242510 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 242037..242510 Neisseria meningitidis FAM18 4676207 YP_974363.1 CDS nuoF NC_008767.1 242900 244201 D NADH dehydrogenase I subunit F 242900..244201 Neisseria meningitidis FAM18 4676191 YP_974364.1 CDS NMC0243 NC_008767.1 244201 244638 D hypothetical protein 244201..244638 Neisseria meningitidis FAM18 4676192 YP_974365.1 CDS nuoG NC_008767.1 244928 247189 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 244928..247189 Neisseria meningitidis FAM18 4674978 YP_974366.1 CDS nuoH NC_008767.1 247186 248268 D NADH dehydrogenase I subunit H 247186..248268 Neisseria meningitidis FAM18 4675963 YP_974367.1 CDS nuoI NC_008767.1 248349 248828 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 248349..248828 Neisseria meningitidis FAM18 4675964 YP_974368.1 CDS nuoJ NC_008767.1 248840 249511 D NADH dehydrogenase I subunit J 248840..249511 Neisseria meningitidis FAM18 4676199 YP_974369.1 CDS nuoK NC_008767.1 249508 249813 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 249508..249813 Neisseria meningitidis FAM18 4676200 YP_974370.1 CDS NMC0249 NC_008767.1 249847 250422 D hypothetical protein 249847..250422 Neisseria meningitidis FAM18 4676194 YP_974371.1 CDS NMC0250 NC_008767.1 250546 250887 D hypothetical protein 250546..250887 Neisseria meningitidis FAM18 4674971 YP_974372.1 CDS nuoL NC_008767.1 250936 252960 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 250936..252960 Neisseria meningitidis FAM18 4674972 YP_974373.1 CDS nuoM NC_008767.1 253049 254545 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 253049..254545 Neisseria meningitidis FAM18 4676195 YP_974374.1 CDS nuoN NC_008767.1 254555 256000 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 254555..256000 Neisseria meningitidis FAM18 4676006 YP_974375.1 CDS NMC0254 NC_008767.1 256061 256411 D inner membrane protei 256061..256411 Neisseria meningitidis FAM18 4676007 YP_974376.1 CDS ispA NC_008767.1 256520 257416 R geranyltranstransferase complement(256520..257416) Neisseria meningitidis FAM18 4674974 YP_974377.1 CDS xseB NC_008767.1 257400 257624 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(257400..257624) Neisseria meningitidis FAM18 4676434 YP_974378.1 CDS NMC0257 NC_008767.1 257735 258658 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(257735..258658) Neisseria meningitidis FAM18 4676666 YP_974379.1 CDS NMC0258 NC_008767.1 258663 260516 R ABC transporter complement(258663..260516) Neisseria meningitidis FAM18 4674973 YP_974380.1 CDS ruvA NC_008767.1 260682 261266 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(260682..261266) Neisseria meningitidis FAM18 4674975 YP_974381.1 CDS NMC0260 NC_008767.1 261348 261728 R hypothetical protein complement(261348..261728) Neisseria meningitidis FAM18 4675529 YP_974382.1 CDS NMC0261 NC_008767.1 261728 262447 R hypothetical protein complement(261728..262447) Neisseria meningitidis FAM18 4674970 YP_974383.1 CDS NMC0262 NC_008767.1 262577 263041 R tRNA/rRNA methyltransferase complement(262577..263041) Neisseria meningitidis FAM18 4674968 YP_974384.1 CDS NMC0263 NC_008767.1 263106 263831 R hypothetical protein complement(263106..263831) Neisseria meningitidis FAM18 4674969 YP_974385.1 CDS NMC0264 NC_008767.1 263803 264573 D hydrolase 263803..264573 Neisseria meningitidis FAM18 4674966 YP_974386.1 CDS NMC0265 NC_008767.1 264575 265363 D hypothetical protein 264575..265363 Neisseria meningitidis FAM18 4674965 YP_974387.1 CDS NMC0267 NC_008767.1 265817 266113 D hypothetical protein 265817..266113 Neisseria meningitidis FAM18 4674967 YP_974388.1 CDS recQ NC_008767.1 266719 269019 R ATP-dependent DNA helicase complement(266719..269019) Neisseria meningitidis FAM18 4674964 YP_974389.1 CDS trpC NC_008767.1 269085 269867 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase complement(269085..269867) Neisseria meningitidis FAM18 4675741 YP_974390.1 CDS NMC0271 NC_008767.1 269918 270874 R hypothetical protein complement(269918..270874) Neisseria meningitidis FAM18 4675187 YP_974391.1 CDS NMC0272 NC_008767.1 271007 272545 R hypothetical protein complement(271007..272545) Neisseria meningitidis FAM18 4674963 YP_974392.1 CDS NMC0273 NC_008767.1 273004 273702 D thiol:disulfide interchange protein 273004..273702 Neisseria meningitidis FAM18 4674959 YP_974393.1 CDS NMC0274 NC_008767.1 273759 274763 R hypothetical protein complement(273759..274763) Neisseria meningitidis FAM18 4674958 YP_974394.1 CDS NMC0275 NC_008767.1 274833 277241 D outer membrane solvent tolerance protein 274833..277241 Neisseria meningitidis FAM18 4674960 YP_974395.1 CDS NMC0276 NC_008767.1 277343 278560 D rotamase 277343..278560 Neisseria meningitidis FAM18 4674961 YP_974396.1 CDS NMC0277 NC_008767.1 280407 281615 D hypothetical protein 280407..281615 Neisseria meningitidis FAM18 4674962 YP_974397.1 CDS NMC0278 NC_008767.1 281636 281947 D hypothetical protein 281636..281947 Neisseria meningitidis FAM18 4674956 YP_974398.1 CDS NMC0279 NC_008767.1 281951 282151 D hypothetical protein 281951..282151 Neisseria meningitidis FAM18 4674957 YP_974399.1 CDS NMC0280 NC_008767.1 282378 282608 D hypothetical protein 282378..282608 Neisseria meningitidis FAM18 4674954 YP_974400.1 CDS NMC0281 NC_008767.1 282636 282938 D hypothetical protein 282636..282938 Neisseria meningitidis FAM18 4674955 YP_974401.1 CDS NMC0282 NC_008767.1 283053 283334 D Doubtful due to large overlap with downstream CDS. Similar to Neisseria meningitidis hypothetical protein NMB1746 SWALL:Q9JY50 (EMBL:AE002524) (96 aa) fasta scores: E(): 0.25, 35.21% id in 71 aa; hypothetical protein 283053..283334 Neisseria meningitidis FAM18 4674953 YP_974402.1 CDS tspB NC_008767.1 283285 284916 D TspB protein 283285..284916 Neisseria meningitidis FAM18 4674951 YP_974403.1 CDS NMC0284 NC_008767.1 285219 285503 D hypothetical protein 285219..285503 Neisseria meningitidis FAM18 4674749 YP_974404.1 CDS NMC0285 NC_008767.1 285504 286691 D hypothetical protein 285504..286691 Neisseria meningitidis FAM18 4674952 YP_974405.1 CDS NMC0286 NC_008767.1 286906 287862 D invertase/transposase 286906..287862 Neisseria meningitidis FAM18 4674948 YP_974406.1 CDS NMC0288 NC_008767.1 288298 290178 R hypothetical protein complement(288298..290178) Neisseria meningitidis FAM18 4674949 YP_974407.1 CDS NMC0289 NC_008767.1 290487 291119 D hypothetical protein 290487..291119 Neisseria meningitidis FAM18 4674950 YP_974408.1 CDS purB NC_008767.1 291191 292561 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 291191..292561 Neisseria meningitidis FAM18 4674947 YP_974409.1 CDS NMC0291 NC_008767.1 292641 294509 D inner membrane trans-acylase protein 292641..294509 Neisseria meningitidis FAM18 4675799 YP_974410.1 CDS dinG NC_008767.1 295254 297404 R helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG complement(295254..297404) Neisseria meningitidis FAM18 4674945 YP_974411.1 CDS NMC0294 NC_008767.1 297476 297706 D hypothetical protein 297476..297706 Neisseria meningitidis FAM18 4675976 YP_974412.1 CDS NMC0295 NC_008767.1 298148 300736 D deleted EC_number 2.1.1.73; DNA methylase 298148..300736 Neisseria meningitidis FAM18 4674946 YP_974413.1 CDS NMC0297 NC_008767.1 301098 302063 D insertion element IS1655 transposase 301098..302063 Neisseria meningitidis FAM18 4674941 YP_974414.1 CDS NMC0298 NC_008767.1 303055 303426 R hypothetical protein complement(303055..303426) Neisseria meningitidis FAM18 4674936 YP_974415.1 CDS NMC0299 NC_008767.1 303741 304745 R transposase for IS1106A3 complement(303741..304745) Neisseria meningitidis FAM18 4674940 YP_974416.1 CDS fabG NC_008767.1 306449 307195 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(306449..307195) Neisseria meningitidis FAM18 4674935 YP_974417.1 CDS guaA NC_008767.1 307257 308822 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(307257..308822) Neisseria meningitidis FAM18 4675885 YP_974418.1 CDS NMC0304 NC_008767.1 308922 310979 R ABC transporter ATP-binding protein complement(308922..310979) Neisseria meningitidis FAM18 4676513 YP_974419.1 CDS fabD NC_008767.1 310925 311851 R malonyl CoA-ACP transacylase complement(310925..311851) Neisseria meningitidis FAM18 4674937 YP_974420.1 CDS NMC0306 NC_008767.1 311945 312352 R hypothetical protein complement(311945..312352) Neisseria meningitidis FAM18 4675876 YP_974421.1 CDS fabH NC_008767.1 312399 313361 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(312399..313361) Neisseria meningitidis FAM18 4674933 YP_974422.1 CDS NMC0308 NC_008767.1 313611 314036 R hypothetical protein complement(313611..314036) Neisseria meningitidis FAM18 4675886 YP_974423.1 CDS NMC0309 NC_008767.1 314054 314305 R hypothetical protein complement(314054..314305) Neisseria meningitidis FAM18 4674934 YP_974424.1 CDS plsX NC_008767.1 314441 315496 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX complement(314441..315496) Neisseria meningitidis FAM18 4674932 YP_974425.1 CDS NMC0311 NC_008767.1 315584 316111 R hypothetical protein complement(315584..316111) Neisseria meningitidis FAM18 4676107 YP_974426.1 CDS rpmF NC_008767.1 316286 316465 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(316286..316465) Neisseria meningitidis FAM18 4674928 YP_974427.1 CDS NMC0313 NC_008767.1 316499 317002 R hypothetical protein complement(316499..317002) Neisseria meningitidis FAM18 4675431 YP_974428.1 CDS NMC0314 NC_008767.1 317150 317740 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 317150..317740 Neisseria meningitidis FAM18 4674931 YP_974429.1 CDS NMC0315 NC_008767.1 317787 318512 D hypothetical protein 317787..318512 Neisseria meningitidis FAM18 4674924 YP_974430.1 CDS NMC0316 NC_008767.1 318593 320230 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC complement(318593..320230) Neisseria meningitidis FAM18 4674920 YP_974431.1 CDS NMC0317 NC_008767.1 320402 320623 R hypothetical protein complement(320402..320623) Neisseria meningitidis FAM18 4674921 YP_974432.1 CDS rnpA NC_008767.1 320688 321053 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(320688..321053) Neisseria meningitidis FAM18 4674922 YP_974433.1 CDS rpmH NC_008767.1 321056 321190 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(321056..321190) Neisseria meningitidis FAM18 4675576 YP_974434.1 CDS dnaA NC_008767.1 321483 323039 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 321483..323039 Neisseria meningitidis FAM18 4675295 YP_974435.1 CDS dnaN NC_008767.1 323119 324222 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 323119..324222 Neisseria meningitidis FAM18 4675939 YP_974436.1 CDS ppk NC_008767.1 324485 326635 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(324485..326635) Neisseria meningitidis FAM18 4675925 YP_974437.1 CDS NMC0324 NC_008767.1 326711 327154 R hypothetical protein complement(326711..327154) Neisseria meningitidis FAM18 4676078 YP_974438.1 CDS mlp NC_008767.1 327161 327676 R lipoprotein complement(327161..327676) Neisseria meningitidis FAM18 4674923 YP_974439.1 CDS leuS NC_008767.1 327943 330573 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 327943..330573 Neisseria meningitidis FAM18 4676288 YP_974440.1 CDS NMC0327 NC_008767.1 330811 331623 D DNA adenine methylase 330811..331623 Neisseria meningitidis FAM18 4676230 YP_974441.1 CDS NMC0328 NC_008767.1 331616 332425 D modification methylase DpnIIB 331616..332425 Neisseria meningitidis FAM18 4674917 YP_974442.1 CDS NMC0329 NC_008767.1 332422 332976 D hypothetical protein 332422..332976 Neisseria meningitidis FAM18 4674918 YP_974443.1 CDS NMC0331 NC_008767.1 333746 334057 R DNA-binding protein complement(333746..334057) Neisseria meningitidis FAM18 4674908 YP_974444.1 CDS NMC0332 NC_008767.1 334054 334395 R hypothetical protein complement(334054..334395) Neisseria meningitidis FAM18 4674914 YP_974445.1 CDS secG NC_008767.1 335322 335672 R preprotein translocase subunit SecG complement(335322..335672) Neisseria meningitidis FAM18 4674911 YP_974446.1 CDS tpiA NC_008767.1 335679 336452 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(335679..336452) Neisseria meningitidis FAM18 4675094 YP_974447.1 CDS NMC0335 NC_008767.1 336612 337139 D hypothetical protein 336612..337139 Neisseria meningitidis FAM18 4674846 YP_974448.1 CDS NMC0336 NC_008767.1 337241 337897 D protein-L-isoaspartate O-methyltransferase 337241..337897 Neisseria meningitidis FAM18 4674905 YP_974449.1 CDS NMC0337 NC_008767.1 337977 338300 D hypothetical protein 337977..338300 Neisseria meningitidis FAM18 4674907 YP_974450.1 CDS NMC0338 NC_008767.1 338717 340894 R ferric siderophore receptor protein complement(338717..340894) Neisseria meningitidis FAM18 4674909 YP_974451.1 CDS NMC0339 NC_008767.1 341008 341331 R hypothetical protein complement(341008..341331) Neisseria meningitidis FAM18 4674904 YP_974452.1 CDS fetB2 NC_008767.1 342383 343348 R ferric enterobactin transporter binding protein complement(342383..343348) Neisseria meningitidis FAM18 4674902 YP_974453.1 CDS NMC0341 NC_008767.1 343584 344540 D AraC family transcriptional regulator 343584..344540 Neisseria meningitidis FAM18 4676589 YP_974454.1 CDS NMC0342 NC_008767.1 344654 346669 R prolyl endopeptidase complement(344654..346669) Neisseria meningitidis FAM18 4674903 YP_974455.1 CDS argA NC_008767.1 346765 348075 R catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase complement(346765..348075) Neisseria meningitidis FAM18 4674898 YP_974456.1 CDS NMC0344 NC_008767.1 348072 348506 R hypothetical protein complement(348072..348506) Neisseria meningitidis FAM18 4676424 YP_974457.1 CDS pyrE NC_008767.1 348580 349221 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(348580..349221) Neisseria meningitidis FAM18 4674900 YP_974458.1 CDS NMC0346 NC_008767.1 349283 350017 R hypothetical protein complement(349283..350017) Neisseria meningitidis FAM18 4675775 YP_974459.1 CDS NMC0347 NC_008767.1 350011 350451 R acetyltransferase complement(350011..350451) Neisseria meningitidis FAM18 4674901 YP_974460.1 CDS NMC0348 NC_008767.1 350448 351125 R hypothetical protein complement(350448..351125) Neisseria meningitidis FAM18 4674897 YP_974461.1 CDS NMC0349 NC_008767.1 351263 352102 R lipoprotein complement(351263..352102) Neisseria meningitidis FAM18 4674891 YP_974462.1 CDS fba NC_008767.1 352242 353306 R class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase complement(352242..353306) Neisseria meningitidis FAM18 4674894 YP_974463.1 CDS xerC NC_008767.1 353500 354417 D integrase/recombinase 353500..354417 Neisseria meningitidis FAM18 4675276 YP_974464.1 CDS dxs NC_008767.1 354502 356415 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 354502..356415 Neisseria meningitidis FAM18 4676538 YP_974465.1 CDS NMC0353 NC_008767.1 356500 357828 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(356500..357828) Neisseria meningitidis FAM18 4675917 YP_974466.1 CDS hemL NC_008767.1 358611 359894 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 358611..359894 Neisseria meningitidis FAM18 4674895 YP_974467.1 CDS orn NC_008767.1 360300 360863 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(360300..360863) Neisseria meningitidis FAM18 4676497 YP_974468.1 CDS prmA NC_008767.1 360881 361768 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase complement(360881..361768) Neisseria meningitidis FAM18 4676120 YP_974469.1 CDS accC NC_008767.1 362029 363390 R acetyl-CoA carboxylase biotin carboxylase component complement(362029..363390) Neisseria meningitidis FAM18 4676054 YP_974470.1 CDS accB NC_008767.1 363502 363957 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(363502..363957) Neisseria meningitidis FAM18 4676205 YP_974471.1 CDS queA NC_008767.1 364274 365353 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 364274..365353 Neisseria meningitidis FAM18 4676204 YP_974472.1 CDS NMC0361 NC_008767.1 365724 366302 R hypothetical protein complement(365724..366302) Neisseria meningitidis FAM18 4675771 YP_974473.1 CDS NMC0362 NC_008767.1 366541 367440 D LysR family transcriptional regulator 366541..367440 Neisseria meningitidis FAM18 4674896 YP_974474.1 CDS carB NC_008767.1 367667 370882 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(367667..370882) Neisseria meningitidis FAM18 4674892 YP_974475.1 CDS NMC0364 NC_008767.1 370889 371437 R hypothetical protein complement(370889..371437) Neisseria meningitidis FAM18 4676541 YP_974476.1 CDS NMC0365 NC_008767.1 371440 372003 R hypothetical protein complement(371440..372003) Neisseria meningitidis FAM18 4674890 YP_974477.1 CDS NMC0366 NC_008767.1 372581 372970 R hypothetical protein complement(372581..372970) Neisseria meningitidis FAM18 4674889 YP_974478.1 CDS NMC0367 NC_008767.1 372967 373227 R hypothetical protein complement(372967..373227) Neisseria meningitidis FAM18 4674886 YP_974479.1 CDS NMC0368 NC_008767.1 373301 373447 R hypothetical protein complement(373301..373447) Neisseria meningitidis FAM18 4674887 YP_974480.1 CDS NMC0369 NC_008767.1 373550 373687 R hypothetical protein complement(373550..373687) Neisseria meningitidis FAM18 4674888 YP_974481.1 CDS carA NC_008767.1 373733 374866 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(373733..374866) Neisseria meningitidis FAM18 4674883 YP_974482.1 CDS pilC1 NC_008767.1 376847 379963 R pilus-associated protein complement(376847..379963) Neisseria meningitidis FAM18 4676525 YP_974483.1 CDS NMC0372 NC_008767.1 380917 381996 R hypothetical protein complement(380917..381996) Neisseria meningitidis FAM18 4676103 YP_974484.1 CDS NMC0373 NC_008767.1 382354 382875 D periplasmic thioredoxin 382354..382875 Neisseria meningitidis FAM18 4674885 YP_974485.1 CDS NMC0374 NC_008767.1 383218 383658 D MarR family transcriptional regulator 383218..383658 Neisseria meningitidis FAM18 4674875 YP_974486.1 CDS NMC0375 NC_008767.1 383773 384273 D NADH:FMN oxidoreductase 383773..384273 Neisseria meningitidis FAM18 4674876 YP_974487.1 CDS NMC0376 NC_008767.1 384289 384984 D sugar-phosphate nucleotidyl transferase 384289..384984 Neisseria meningitidis FAM18 4674877 YP_974488.1 CDS NMC0377 NC_008767.1 385215 385646 R hypothetical protein complement(385215..385646) Neisseria meningitidis FAM18 4674874 YP_974489.1 CDS fhs NC_008767.1 385821 387497 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 385821..387497 Neisseria meningitidis FAM18 4674871 YP_974490.1 CDS NMC0379 NC_008767.1 387611 388702 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 387611..388702 Neisseria meningitidis FAM18 4676677 YP_974491.1 CDS NMC0380 NC_008767.1 389077 390959 D lipopolysaccharide modification acyltransferase join(389077..389259,389262..390959) Neisseria meningitidis FAM18 4674872 YP_974492.1 CDS tyrS NC_008767.1 391022 392317 D tyrosyl-tRNA synthetase 391022..392317 Neisseria meningitidis FAM18 4674870 YP_974493.1 CDS ribF NC_008767.1 392808 393764 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 392808..393764 Neisseria meningitidis FAM18 4676483 YP_974494.1 CDS ileS NC_008767.1 393905 396694 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 393905..396694 Neisseria meningitidis FAM18 4675586 YP_974495.1 CDS lspA NC_008767.1 397998 398495 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 397998..398495 Neisseria meningitidis FAM18 4676440 YP_974496.1 CDS ispH NC_008767.1 398524 399492 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 398524..399492 Neisseria meningitidis FAM18 4676329 YP_974497.1 CDS NMC0386 NC_008767.1 399579 400238 R phosphatase complement(399579..400238) Neisseria meningitidis FAM18 4676331 YP_974498.1 CDS NMC0387 NC_008767.1 400386 402554 D TonB-dependent receptor 400386..402554 Neisseria meningitidis FAM18 4674869 YP_974499.1 CDS NMC0388 NC_008767.1 402624 403556 D esterase 402624..403556 Neisseria meningitidis FAM18 4674861 YP_974500.1 CDS dnaE NC_008767.1 403990 407424 R DNA polymerase III subunit alpha complement(403990..407424) Neisseria meningitidis FAM18 4674864 YP_974501.1 CDS NMC0390 NC_008767.1 407587 407823 D hypothetical protein 407587..407823 Neisseria meningitidis FAM18 4675957 YP_974502.1 CDS NMC0392 NC_008767.1 407801 408004 D hypothetical protein 407801..408004 Neisseria meningitidis FAM18 4674868 YP_974503.1 CDS NMC0393 NC_008767.1 408109 408510 D hypothetical protein 408109..408510 Neisseria meningitidis FAM18 4674860 YP_974504.1 CDS NMC0394 NC_008767.1 408820 409656 D hypothetical protein 408820..409656 Neisseria meningitidis FAM18 4674855 YP_974505.1 CDS avtA NC_008767.1 409708 411000 R transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase complement(409708..411000) Neisseria meningitidis FAM18 4674858 YP_974506.1 CDS pglD NC_008767.1 411056 412966 R pilin glycosylation protein complement(411056..412966) Neisseria meningitidis FAM18 4676676 YP_974507.1 CDS pglC NC_008767.1 413014 414189 R pilin glycosylation protein complement(413014..414189) Neisseria meningitidis FAM18 4676147 YP_974508.1 CDS NMC0398 NC_008767.1 414660 415346 R hydrolase, haloacid dehalogenase-like hydrolase complement(414660..415346) Neisseria meningitidis FAM18 4676146 YP_974509.1 CDS NMC0399 NC_008767.1 415333 416911 R protein Pglb2 complement(join(415333..416301,416300..416911)) Neisseria meningitidis FAM18 4674857 YP_974510.1 CDS NMC0400 NC_008767.1 416904 418076 R hypothetical protein complement(416904..418076) Neisseria meningitidis FAM18 4674859 YP_974511.1 CDS NMC0401 NC_008767.1 418090 419173 R hypothetical protein complement(join(418090..418671,418673..419173)) Neisseria meningitidis FAM18 4674854 YP_974512.1 CDS NMC0402 NC_008767.1 419170 420597 R lipopolysaccharide biosynthesis translocase complement(419170..420597) Neisseria meningitidis FAM18 4674856 YP_974513.1 CDS ribD NC_008767.1 420792 421901 R diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase complement(420792..421901) Neisseria meningitidis FAM18 4674849 YP_974514.1 CDS nrdR NC_008767.1 421934 422398 R transcriptional regulator NrdR complement(421934..422398) Neisseria meningitidis FAM18 4675539 YP_974515.1 CDS NMC0405 NC_008767.1 422427 423269 R hypothetical protein complement(422427..423269) Neisseria meningitidis FAM18 4674853 YP_974516.1 CDS aroB NC_008767.1 424559 425638 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(424559..425638) Neisseria meningitidis FAM18 4674848 YP_974517.1 CDS aroK NC_008767.1 425718 426233 R catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(425718..426233) Neisseria meningitidis FAM18 4675592 YP_974518.1 CDS pilQ NC_008767.1 427192 428962 R pilus secretin complement(join(427192..428472,428474..428962)) Neisseria meningitidis FAM18 4675619 YP_974519.1 CDS pilP NC_008767.1 428981 429526 R pilus assembly protein complement(428981..429526) Neisseria meningitidis FAM18 4676098 YP_974520.1 CDS pilO NC_008767.1 429544 430191 R pilus assembly protein complement(429544..430191) Neisseria meningitidis FAM18 4676097 YP_974521.1 CDS pilN NC_008767.1 430192 430791 R pilus assembly protein complement(430192..430791) Neisseria meningitidis FAM18 4676015 YP_974522.1 CDS pilM NC_008767.1 430794 431909 R pilus assembly protein complement(430794..431909) Neisseria meningitidis FAM18 4676014 YP_974523.1 CDS ponA NC_008767.1 432061 434457 D penicillin-binding protein 1 432061..434457 Neisseria meningitidis FAM18 4676110 YP_974524.1 CDS engB NC_008767.1 434578 435207 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(434578..435207) Neisseria meningitidis FAM18 4676093 YP_974525.1 CDS cyc NC_008767.1 435413 436036 D cytochrome C 435413..436036 Neisseria meningitidis FAM18 4674850 YP_974526.1 CDS NMC0417 NC_008767.1 436250 438265 D hypothetical protein 436250..438265 Neisseria meningitidis FAM18 4675812 YP_974527.1 CDS NMC0418 NC_008767.1 438258 439445 D hypothetical protein 438258..439445 Neisseria meningitidis FAM18 4674842 YP_974528.1 CDS gcp NC_008767.1 439561 440625 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 439561..440625 Neisseria meningitidis FAM18 4674844 YP_974529.1 CDS NMC0421 NC_008767.1 440669 441565 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(440669..441565) Neisseria meningitidis FAM18 4676596 YP_974530.1 CDS metK NC_008767.1 441911 443080 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 441911..443080 Neisseria meningitidis FAM18 4674837 YP_974531.1 CDS NMC0423 NC_008767.1 443572 444223 D insertion element IS1016 transposase join(443572..444030,444032..444223) Neisseria meningitidis FAM18 4676319 YP_974532.1 CDS NMC0425 NC_008767.1 444299 445708 R peptidase complement(444299..445708) Neisseria meningitidis FAM18 4674841 YP_974533.1 CDS NMC0426 NC_008767.1 445873 446439 D oxidoreductase 445873..446439 Neisseria meningitidis FAM18 4674836 YP_974534.1 CDS NMC0427 NC_008767.1 447005 448321 D transmembrane transport protein 447005..448321 Neisseria meningitidis FAM18 4674835 YP_974535.1 CDS NMC0428 NC_008767.1 448529 448675 D two-component system response regulator 448529..448675 Neisseria meningitidis FAM18 4674833 YP_974536.1 CDS NMC0429 NC_008767.1 448715 449965 D two-component system sensor kinase 448715..449965 Neisseria meningitidis FAM18 4674826 YP_974537.1 CDS NMC0430 NC_008767.1 449999 451492 R hypothetical protein complement(449999..451492) Neisseria meningitidis FAM18 4674825 YP_974538.1 CDS NMC0431 NC_008767.1 451681 451962 D glutaredoxin 451681..451962 Neisseria meningitidis FAM18 4674824 YP_974539.1 CDS secB NC_008767.1 451983 452426 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 451983..452426 Neisseria meningitidis FAM18 4674823 YP_974540.1 CDS recG NC_008767.1 452512 454554 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 452512..454554 Neisseria meningitidis FAM18 4675100 YP_974541.1 CDS argC NC_008767.1 455710 456753 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(455710..456753) Neisseria meningitidis FAM18 4675758 YP_974542.1 CDS NMC0435 NC_008767.1 456750 457031 R hypothetical protein complement(456750..457031) Neisseria meningitidis FAM18 4676426 YP_974543.1 CDS NMC0436 NC_008767.1 457285 458440 D hypothetical protein join(457285..457335,457337..458440) Neisseria meningitidis FAM18 4674819 YP_974544.1 CDS NMC0437 NC_008767.1 458437 458676 D lipoprotein 458437..458676 Neisseria meningitidis FAM18 4674816 YP_974545.1 CDS NMC0438 NC_008767.1 458669 459022 D hypothetical protein 458669..459022 Neisseria meningitidis FAM18 4674815 YP_974546.1 CDS NMC0439 NC_008767.1 459083 459861 D secretion protein join(459083..459610,459613..459861) Neisseria meningitidis FAM18 4674812 YP_974547.1 CDS NMC0440 NC_008767.1 460170 460472 D hypothetical protein 460170..460472 Neisseria meningitidis FAM18 4674811 YP_974548.1 CDS NMC0441 NC_008767.1 460487 460657 D hypothetical protein 460487..460657 Neisseria meningitidis FAM18 4674810 YP_974549.1 CDS NMC0443 NC_008767.1 461056 462798 D hemolysin activator 461056..462798 Neisseria meningitidis FAM18 4674809 YP_974550.1 CDS NMC0444 NC_008767.1 462907 468987 D hemagglutinin 462907..468987 Neisseria meningitidis FAM18 4674808 YP_974551.1 CDS NMC0445 NC_008767.1 468994 469503 D hypothetical protein 468994..469503 Neisseria meningitidis FAM18 4674807 YP_974552.1 CDS NMC0447 NC_008767.1 471672 472046 D hypothetical protein 471672..472046 Neisseria meningitidis FAM18 4674805 YP_974553.1 CDS rte5 NC_008767.1 472359 473861 D hemagglutinin/hemolysin-like protein 472359..473861 Neisseria meningitidis FAM18 4674804 YP_974554.1 CDS NMC0449 NC_008767.1 473880 474143 D hypothetical protein 473880..474143 Neisseria meningitidis FAM18 4675124 YP_974555.1 CDS NMC0450 NC_008767.1 474250 476637 D hemagglutinin/hemolysin-like protein 474250..476637 Neisseria meningitidis FAM18 4674803 YP_974556.1 CDS NMC0451 NC_008767.1 476642 477025 D hypothetical protein 476642..477025 Neisseria meningitidis FAM18 4674802 YP_974557.1 CDS NMC0452 NC_008767.1 477275 479776 D hemagglutinin 477275..479776 Neisseria meningitidis FAM18 4674801 YP_974558.1 CDS NMC0453 NC_008767.1 479773 480261 D hypothetical protein 479773..480261 Neisseria meningitidis FAM18 4674800 YP_974559.1 CDS NMC0454 NC_008767.1 480449 480721 D hypothetical protein 480449..480721 Neisseria meningitidis FAM18 4674799 YP_974560.1 CDS NMC0456 NC_008767.1 480925 481893 D hypothetical protein 480925..481893 Neisseria meningitidis FAM18 4674796 YP_974561.1 CDS NMC0457 NC_008767.1 481896 482831 D hypothetical protein 481896..482831 Neisseria meningitidis FAM18 4674795 YP_974562.1 CDS NMC0458 NC_008767.1 483601 483879 D hypothetical protein 483601..483879 Neisseria meningitidis FAM18 4674793 YP_974563.1 CDS NMC0459 NC_008767.1 484162 484620 D hypothetical protein 484162..484620 Neisseria meningitidis FAM18 4674791 YP_974564.1 CDS rbn NC_008767.1 485133 486359 R RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; this protein contains a C-terminal extension of unknown function; ribonuclease BN/unknown domain fusion protein complement(485133..486359) Neisseria meningitidis FAM18 4674790 YP_974565.1 CDS NMC0464 NC_008767.1 486904 487563 D hypothetical protein 486904..487563 Neisseria meningitidis FAM18 4674789 YP_974566.1 CDS NMC0465 NC_008767.1 487591 488106 D hypothetical protein 487591..488106 Neisseria meningitidis FAM18 4674788 YP_974567.1 CDS NMC0466 NC_008767.1 488113 488535 D hypothetical protein 488113..488535 Neisseria meningitidis FAM18 4674785 YP_974568.1 CDS NMC0467 NC_008767.1 488804 489175 D hypothetical protein 488804..489175 Neisseria meningitidis FAM18 4674784 YP_974569.1 CDS NMC0468 NC_008767.1 489172 489810 D hypothetical protein 489172..489810 Neisseria meningitidis FAM18 4674781 YP_974570.1 CDS NMC0469 NC_008767.1 490450 491535 R hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase complement(490450..491535) Neisseria meningitidis FAM18 4674779 YP_974571.1 CDS NMC0470 NC_008767.1 491592 493112 R hypothetical protein complement(491592..493112) Neisseria meningitidis FAM18 4674778 YP_974572.1 CDS NMC0471 NC_008767.1 493312 494811 R periplasmic serine protease complement(493312..494811) Neisseria meningitidis FAM18 4674777 YP_974573.1 CDS nth NC_008767.1 494949 495578 R endonuclease III complement(494949..495578) Neisseria meningitidis FAM18 4674776 YP_974574.1 CDS NMC0473 NC_008767.1 495624 496052 R hypothetical protein complement(495624..496052) Neisseria meningitidis FAM18 4676211 YP_974575.1 CDS NMC0474 NC_008767.1 496627 497850 D transmembrane hexose transporter 496627..497850 Neisseria meningitidis FAM18 4674773 YP_974576.1 CDS NMC0475 NC_008767.1 498141 499520 D transmembrane transport protein 498141..499520 Neisseria meningitidis FAM18 4674771 YP_974577.1 CDS NMC0476 NC_008767.1 499649 500473 R hypothetical protein complement(499649..500473) Neisseria meningitidis FAM18 4674770 YP_974578.1 CDS NMC0477 NC_008767.1 500475 500990 R hypothetical protein complement(500475..500990) Neisseria meningitidis FAM18 4674769 YP_974579.1 CDS hemC NC_008767.1 501109 502044 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 501109..502044 Neisseria meningitidis FAM18 4674768 YP_974580.1 CDS aspC NC_008767.1 502447 503640 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(502447..503640) Neisseria meningitidis FAM18 4676351 YP_974581.1 CDS NMC0480 NC_008767.1 503722 504219 R hypothetical protein complement(503722..504219) Neisseria meningitidis FAM18 4675643 YP_974582.1 CDS NMC0481 NC_008767.1 504335 504538 D hypothetical protein 504335..504538 Neisseria meningitidis FAM18 4674767 YP_974583.1 CDS NMC0482 NC_008767.1 504706 506292 R transmembrane transport protein complement(504706..506292) Neisseria meningitidis FAM18 4674764 YP_974584.1 CDS NMC0483 NC_008767.1 506561 507283 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(506561..507283) Neisseria meningitidis FAM18 4674763 YP_974585.1 CDS NMC0484 NC_008767.1 507533 511018 D hypothetical protein 507533..511018 Neisseria meningitidis FAM18 4674762 YP_974586.1 CDS adhA NC_008767.1 511369 512415 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(511369..512415) Neisseria meningitidis FAM18 4674761 YP_974587.1 CDS NMC0487 NC_008767.1 512699 513088 R pilin complement(512699..513088) Neisseria meningitidis FAM18 4675518 YP_974588.1 CDS NMC0488 NC_008767.1 513314 514492 D hypothetical protein 513314..514492 Neisseria meningitidis FAM18 4674760 YP_974589.1 CDS NMC0489 NC_008767.1 514558 516492 D ABC transporter ATP-binding protein 514558..516492 Neisseria meningitidis FAM18 4674759 YP_974590.1 CDS NMC0490 NC_008767.1 516795 517637 R thiol:disulfide interchange protein complement(516795..517637) Neisseria meningitidis FAM18 4674758 YP_974591.1 CDS priA NC_008767.1 517734 519923 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 517734..519923 Neisseria meningitidis FAM18 4674756 YP_974592.1 CDS NMC0493 NC_008767.1 519970 521082 R hypothetical protein complement(519970..521082) Neisseria meningitidis FAM18 4675970 YP_974593.1 CDS NMC0494 NC_008767.1 521091 522047 R transposase complement(521091..522047) Neisseria meningitidis FAM18 4674746 YP_974594.1 CDS dnaK NC_008767.1 523485 525413 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(523485..525413) Neisseria meningitidis FAM18 4676715 YP_974595.1 CDS NMC0496 NC_008767.1 525621 525893 R hypothetical protein complement(525621..525893) Neisseria meningitidis FAM18 4675944 YP_974596.1 CDS NMC0497 NC_008767.1 526079 526765 D transcriptional regulator 526079..526765 Neisseria meningitidis FAM18 4675147 YP_974597.1 CDS NMC0498 NC_008767.1 526897 527235 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 526897..527235 Neisseria meningitidis FAM18 4674753 YP_974598.1 CDS NMC0499 NC_008767.1 527395 527859 D hypothetical protein 527395..527859 Neisseria meningitidis FAM18 4674751 YP_974599.1 CDS ubiB NC_008767.1 527894 529405 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 527894..529405 Neisseria meningitidis FAM18 4675137 YP_974600.1 CDS cysE NC_008767.1 529762 530580 R serine acetyltransferase complement(529762..530580) Neisseria meningitidis FAM18 4676711 YP_974601.1 CDS grpE NC_008767.1 530764 531342 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 530764..531342 Neisseria meningitidis FAM18 4675632 YP_974602.1 CDS NMC0503 NC_008767.1 531466 531681 R hypothetical protein complement(531466..531681) Neisseria meningitidis FAM18 4676251 YP_974603.1 CDS apbE NC_008767.1 531707 532783 R thiamine biosynthesis protein complement(531707..532783) Neisseria meningitidis FAM18 4675151 YP_974604.1 CDS nqrF NC_008767.1 532914 534131 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F complement(532914..534131) Neisseria meningitidis FAM18 4676372 YP_974605.1 CDS nqrE NC_008767.1 534145 534738 R Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E complement(534145..534738) Neisseria meningitidis FAM18 4676124 YP_974606.1 CDS nqrD NC_008767.1 534742 535368 R Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D complement(534742..535368) Neisseria meningitidis FAM18 4676217 YP_974607.1 CDS nqrC NC_008767.1 535368 536144 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C complement(535368..536144) Neisseria meningitidis FAM18 4676216 YP_974608.1 CDS nqrB NC_008767.1 536137 537369 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B complement(536137..537369) Neisseria meningitidis FAM18 4676232 YP_974609.1 CDS nqrA NC_008767.1 537372 538715 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A complement(537372..538715) Neisseria meningitidis FAM18 4676231 YP_974610.1 CDS NMC0512 NC_008767.1 539063 540502 R hypothetical protein complement(539063..540502) Neisseria meningitidis FAM18 4676223 YP_974611.1 CDS NMC0513 NC_008767.1 540842 541201 R hypothetical protein complement(540842..541201) Neisseria meningitidis FAM18 4675155 YP_974612.1 CDS NMC0514 NC_008767.1 541198 541803 R hypothetical protein complement(541198..541803) Neisseria meningitidis FAM18 4676710 YP_974613.1 CDS NMC0515 NC_008767.1 541850 542332 R AsnC family transcriptional regulator complement(541850..542332) Neisseria meningitidis FAM18 4674919 YP_974614.1 CDS gcvT NC_008767.1 542838 543944 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 542838..543944 Neisseria meningitidis FAM18 4675213 YP_974615.1 CDS gcvH NC_008767.1 544107 544493 D part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 544107..544493 Neisseria meningitidis FAM18 4676617 YP_974616.1 CDS hemA NC_008767.1 544645 545892 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 544645..545892 Neisseria meningitidis FAM18 4676633 YP_974617.1 CDS NMC0519 NC_008767.1 546168 546740 D regulatory protein 546168..546740 Neisseria meningitidis FAM18 4676508 YP_974618.1 CDS NMC0520 NC_008767.1 546743 547828 D hypothetical protein 546743..547828 Neisseria meningitidis FAM18 4675182 YP_974619.1 CDS NMC0521 NC_008767.1 547886 548506 D ABC transporter ATP-binding protein 547886..548506 Neisseria meningitidis FAM18 4676246 YP_974620.1 CDS NMC0522 NC_008767.1 548723 549217 D lipoprotein 548723..549217 Neisseria meningitidis FAM18 4675221 YP_974621.1 CDS NMC0523 NC_008767.1 549351 551012 R electron transfer flavoprotein-ubiquinone oxidoreductase complement(549351..551012) Neisseria meningitidis FAM18 4675222 YP_974622.1 CDS NMC0524 NC_008767.1 551142 551684 R peptidase complement(551142..551684) Neisseria meningitidis FAM18 4675220 YP_974623.1 CDS NMC0525 NC_008767.1 552629 553282 R transposase complement(552629..553282) Neisseria meningitidis FAM18 4675226 YP_974624.1 CDS NMC0526 NC_008767.1 553888 554703 D hypothetical protein 553888..554703 Neisseria meningitidis FAM18 4675225 YP_974625.1 CDS frpC NC_008767.1 554720 560809 D iron-regulated protein FrpC 554720..560809 Neisseria meningitidis FAM18 4675231 YP_974626.1 CDS NMC0528 NC_008767.1 561089 562003 R periplasmic binding protein complement(561089..562003) Neisseria meningitidis FAM18 4676685 YP_974627.1 CDS NMC0529 NC_008767.1 562080 562955 R ABC-transporter membrane protein complement(562080..562955) Neisseria meningitidis FAM18 4675244 YP_974628.1 CDS NMC0530 NC_008767.1 562979 563734 R ABC transporter ATP-binding protein complement(562979..563734) Neisseria meningitidis FAM18 4675138 YP_974629.1 CDS rplS NC_008767.1 564026 564391 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(564026..564391) Neisseria meningitidis FAM18 4675173 YP_974630.1 CDS trmD NC_008767.1 564407 565156 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(564407..565156) Neisseria meningitidis FAM18 4675382 YP_974631.1 CDS rimM NC_008767.1 565156 565665 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(565156..565665) Neisseria meningitidis FAM18 4674831 YP_974632.1 CDS rpsP NC_008767.1 565681 565926 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(565681..565926) Neisseria meningitidis FAM18 4675587 YP_974633.1 CDS NMC0535 NC_008767.1 565971 568397 R hypothetical protein complement(565971..568397) Neisseria meningitidis FAM18 4675224 YP_974634.1 CDS NMC0536 NC_008767.1 568515 569921 R two-component system sensor kinase complement(568515..569921) Neisseria meningitidis FAM18 4675172 YP_974635.1 CDS NMC0537 NC_008767.1 569934 570611 R two-component system regulator complement(569934..570611) Neisseria meningitidis FAM18 4675248 YP_974636.1 CDS NMC0539 NC_008767.1 570801 572615 R hypothetical protein complement(570801..572615) Neisseria meningitidis FAM18 4675249 YP_974637.1 CDS NMC0540 NC_008767.1 572605 572958 R hypothetical protein complement(572605..572958) Neisseria meningitidis FAM18 4675252 YP_974638.1 CDS NMC0541 NC_008767.1 572967 573575 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(572967..573575) Neisseria meningitidis FAM18 4675245 YP_974639.1 CDS tatC NC_008767.1 573628 574398 R sec-independent protein translocase component complement(573628..574398) Neisseria meningitidis FAM18 4676044 YP_974640.1 CDS NMC0543 NC_008767.1 574412 575098 R sec-independent protein translocase component complement(574412..575098) Neisseria meningitidis FAM18 4675207 YP_974641.1 CDS NMC0545 NC_008767.1 575352 575675 R nucleotide-binding protein complement(575352..575675) Neisseria meningitidis FAM18 4675162 YP_974642.1 CDS hisE NC_008767.1 575747 576070 R catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase complement(575747..576070) Neisseria meningitidis FAM18 4675341 YP_974643.1 CDS NMC0547 NC_008767.1 576211 577275 R zinc-binding alcohol dehydrogenase complement(576211..577275) Neisseria meningitidis FAM18 4676484 YP_974644.1 CDS NMC0548 NC_008767.1 577638 578747 R hypothetical protein complement(577638..578747) Neisseria meningitidis FAM18 4675143 YP_974645.1 CDS NMC0549 NC_008767.1 578875 579141 D hypothetical protein 578875..579141 Neisseria meningitidis FAM18 4675349 YP_974646.1 CDS secD NC_008767.1 579350 581206 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 579350..581206 Neisseria meningitidis FAM18 4675300 YP_974647.1 CDS secF NC_008767.1 581210 582145 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 581210..582145 Neisseria meningitidis FAM18 4675101 YP_974648.1 CDS rpsO NC_008767.1 582368 582637 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 582368..582637 Neisseria meningitidis FAM18 4675215 YP_974649.1 CDS NMC0553 NC_008767.1 583019 584143 D polyamine permease ATP-binding protein 583019..584143 Neisseria meningitidis FAM18 4675223 YP_974650.1 CDS NMC0554 NC_008767.1 584159 585124 D polyamine permease inner membrane protein 584159..585124 Neisseria meningitidis FAM18 4675352 YP_974651.1 CDS NMC0555 NC_008767.1 585124 586011 D polyamine permease inner membrane protein 585124..586011 Neisseria meningitidis FAM18 4675305 YP_974652.1 CDS NMC0556 NC_008767.1 586137 587432 D oxidoreductase 586137..587432 Neisseria meningitidis FAM18 4675253 YP_974653.1 CDS amtB NC_008767.1 587677 588981 R ammonium transporter complement(587677..588981) Neisseria meningitidis FAM18 4675307 YP_974654.1 CDS NMC0558 NC_008767.1 590199 590594 R IS1106 transposase complement(590199..590594) Neisseria meningitidis FAM18 4676375 YP_974655.1 CDS rho NC_008767.1 591470 592729 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(591470..592729) Neisseria meningitidis FAM18 4675309 YP_974656.1 CDS ppsA NC_008767.1 592949 595333 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(592949..595333) Neisseria meningitidis FAM18 4675601 YP_974657.1 CDS NMC0562 NC_008767.1 595744 596565 D hypothetical protein 595744..596565 Neisseria meningitidis FAM18 4676079 YP_974658.1 CDS NMC0563 NC_008767.1 596804 597466 R phosphatase complement(596804..597466) Neisseria meningitidis FAM18 4675308 YP_974659.1 CDS NMC0565 NC_008767.1 597479 598333 R hypothetical protein complement(597479..598333) Neisseria meningitidis FAM18 4675310 YP_974660.1 CDS NMC0566 NC_008767.1 598734 599357 D periplasmic carrier protein 598734..599357 Neisseria meningitidis FAM18 4675314 YP_974661.1 CDS NMC0567 NC_008767.1 599609 600769 D polyamine permease substrate-binding protein 599609..600769 Neisseria meningitidis FAM18 4675312 YP_974662.1 CDS NMC0568 NC_008767.1 600903 602082 D glycosyl transferase join(600903..601232,601240..602082) Neisseria meningitidis FAM18 4675319 YP_974663.1 CDS NMC0569 NC_008767.1 602123 602653 D hypothetical protein 602123..602653 Neisseria meningitidis FAM18 4675322 YP_974664.1 CDS prfC NC_008767.1 602822 604417 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(602822..604417) Neisseria meningitidis FAM18 4675321 YP_974665.1 CDS hisI NC_008767.1 604524 604919 R PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase complement(604524..604919) Neisseria meningitidis FAM18 4675969 YP_974666.1 CDS hisF NC_008767.1 604950 605717 R catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF complement(604950..605717) Neisseria meningitidis FAM18 4676452 YP_974667.1 CDS hisA NC_008767.1 605730 606467 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase complement(605730..606467) Neisseria meningitidis FAM18 4676485 YP_974668.1 CDS hisH NC_008767.1 606500 607138 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(606500..607138) Neisseria meningitidis FAM18 4676476 YP_974669.1 CDS NMC0575 NC_008767.1 607269 608903 R phosphate acyltransferase complement(607269..608903) Neisseria meningitidis FAM18 4676430 YP_974670.1 CDS fbpC NC_008767.1 608956 610014 R iron-uptake permease ATP-binding protein complement(608956..610014) Neisseria meningitidis FAM18 4675330 YP_974671.1 CDS fbpB NC_008767.1 610035 611570 R iron-uptake permease inner membrane protein complement(610035..611570) Neisseria meningitidis FAM18 4675853 YP_974672.1 CDS fbpA NC_008767.1 611620 612615 R major ferric iron binding protein complement(611620..612615) Neisseria meningitidis FAM18 4675848 YP_974673.1 CDS NMC0579 NC_008767.1 612866 613336 R hypothetical protein complement(612866..613336) Neisseria meningitidis FAM18 4675847 YP_974674.1 CDS argH NC_008767.1 613394 614770 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(613394..614770) Neisseria meningitidis FAM18 4675327 YP_974675.1 CDS galU NC_008767.1 614789 615658 R UTP-glucose-1-phosphate uridylyltransferase complement(614789..615658) Neisseria meningitidis FAM18 4675867 YP_974676.1 CDS NMC0582 NC_008767.1 615686 616285 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase complement(615686..616285) Neisseria meningitidis FAM18 4676629 YP_974677.1 CDS NMC0583 NC_008767.1 616278 616511 R hypothetical protein complement(616278..616511) Neisseria meningitidis FAM18 4675165 YP_974678.1 CDS ppa NC_008767.1 616619 617200 R inorganic pyrophosphatase complement(616619..617200) Neisseria meningitidis FAM18 4675332 YP_974679.1 CDS ntpA NC_008767.1 617253 617711 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(617253..617711) Neisseria meningitidis FAM18 4676080 YP_974680.1 CDS mafB3 NC_008767.1 618156 619982 D adhesin 618156..619982 Neisseria meningitidis FAM18 4676212 YP_974681.1 CDS NMC0587 NC_008767.1 619985 620449 D hypothetical protein 619985..620449 Neisseria meningitidis FAM18 4675934 YP_974682.1 CDS NMC0588 NC_008767.1 620475 620663 D lipoprotein 620475..620663 Neisseria meningitidis FAM18 4675174 YP_974683.1 CDS NMC0589 NC_008767.1 620832 621119 D ribonuclease inhibitor barstar 620832..621119 Neisseria meningitidis FAM18 4675500 YP_974684.1 CDS NMC0591 NC_008767.1 622433 622855 D hypothetical protein 622433..622855 Neisseria meningitidis FAM18 4675432 YP_974685.1 CDS NMC0592 NC_008767.1 623013 623255 D hypothetical protein 623013..623255 Neisseria meningitidis FAM18 4675342 YP_974686.1 CDS NMC0593 NC_008767.1 623333 623578 D hypothetical protein 623333..623578 Neisseria meningitidis FAM18 4675436 YP_974687.1 CDS NMC0594 NC_008767.1 623581 623967 D hypothetical protein 623581..623967 Neisseria meningitidis FAM18 4675360 YP_974688.1 CDS NMC0595 NC_008767.1 624068 624457 D hypothetical protein 624068..624457 Neisseria meningitidis FAM18 4675366 YP_974689.1 CDS NMC0596 NC_008767.1 624579 625520 D adhesin 624579..625520 Neisseria meningitidis FAM18 4675456 YP_974690.1 CDS NMC0597 NC_008767.1 625524 626792 D adhesin 625524..626792 Neisseria meningitidis FAM18 4675454 YP_974691.1 CDS NMC0598 NC_008767.1 626795 627112 D hypothetical protein 626795..627112 Neisseria meningitidis FAM18 4675453 YP_974692.1 CDS NMC0599 NC_008767.1 627246 627923 D hypothetical protein 627246..627923 Neisseria meningitidis FAM18 4675459 YP_974693.1 CDS NMC0600 NC_008767.1 627929 628306 D hypothetical protein 627929..628306 Neisseria meningitidis FAM18 4675455 YP_974694.1 CDS NMC0601 NC_008767.1 628437 629105 D hypothetical protein 628437..629105 Neisseria meningitidis FAM18 4675460 YP_974695.1 CDS NMC0602 NC_008767.1 629109 629381 D hypothetical protein 629109..629381 Neisseria meningitidis FAM18 4675475 YP_974696.1 CDS NMC0603 NC_008767.1 629363 629515 D hypothetical protein 629363..629515 Neisseria meningitidis FAM18 4675470 YP_974697.1 CDS NMC0604 NC_008767.1 629502 630047 D hypothetical protein 629502..630047 Neisseria meningitidis FAM18 4675476 YP_974698.1 CDS NMC0605 NC_008767.1 630041 630664 D hypothetical protein 630041..630664 Neisseria meningitidis FAM18 4676473 YP_974699.1 CDS NMC0606 NC_008767.1 630897 631076 D fragment because of a substitution M->H; hypothetical protein 630897..631076 Neisseria meningitidis FAM18 4675478 YP_974700.1 CDS NMC0607 NC_008767.1 631107 631508 D hypothetical protein 631107..631508 Neisseria meningitidis FAM18 4675479 YP_974701.1 CDS NMC0608 NC_008767.1 631690 632079 D hypothetical protein 631690..632079 Neisseria meningitidis FAM18 4676418 YP_974702.1 CDS NMC0609 NC_008767.1 632120 633577 R transmembrane potassium transporter complement(632120..633577) Neisseria meningitidis FAM18 4675511 YP_974703.1 CDS apaH NC_008767.1 633592 634482 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(633592..634482) Neisseria meningitidis FAM18 4675527 YP_974704.1 CDS NMC0611 NC_008767.1 634500 634889 R hypothetical protein complement(634500..634889) Neisseria meningitidis FAM18 4676371 YP_974705.1 CDS nspA NC_008767.1 635025 635549 R hypothetical protein complement(635025..635549) Neisseria meningitidis FAM18 4675980 YP_974706.1 CDS NMC0613 NC_008767.1 636136 637335 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(636136..637335) Neisseria meningitidis FAM18 4676221 YP_974707.1 CDS ligA NC_008767.1 637368 639893 R DNA ligase complement(637368..639893) Neisseria meningitidis FAM18 4675503 YP_974708.1 CDS NMC0615 NC_008767.1 640041 641327 R hypothetical protein complement(640041..641327) Neisseria meningitidis FAM18 4676381 YP_974709.1 CDS ampD NC_008767.1 641523 642095 R N-acetyl-anhydromuranmyl-L-alanine amidase complement(641523..642095) Neisseria meningitidis FAM18 4675580 YP_974710.1 CDS NMC0618 NC_008767.1 642122 643174 D hypothetical protein 642122..643174 Neisseria meningitidis FAM18 4676374 YP_974711.1 CDS tmk NC_008767.1 643234 643854 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 643234..643854 Neisseria meningitidis FAM18 4675577 YP_974712.1 CDS maeA NC_008767.1 644076 645356 D malate oxidoreductase 644076..645356 Neisseria meningitidis FAM18 4674866 YP_974713.1 CDS lpxK NC_008767.1 645903 646937 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 645903..646937 Neisseria meningitidis FAM18 4676332 YP_974714.1 CDS NMC0622 NC_008767.1 647137 647724 D hypothetical protein 647137..647724 Neisseria meningitidis FAM18 4676328 YP_974715.1 CDS NMC0623 NC_008767.1 647793 647975 D hypothetical protein 647793..647975 Neisseria meningitidis FAM18 4675531 YP_974716.1 CDS kdsB NC_008767.1 647972 648733 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 647972..648733 Neisseria meningitidis FAM18 4675581 YP_974717.1 CDS NMC0625 NC_008767.1 648756 649157 D hypothetical protein 648756..649157 Neisseria meningitidis FAM18 4676405 YP_974718.1 CDS NMC0626 NC_008767.1 649178 649375 D hypothetical protein 649178..649375 Neisseria meningitidis FAM18 4675600 YP_974719.1 CDS NMC0627 NC_008767.1 649353 649469 D hypothetical protein 649353..649469 Neisseria meningitidis FAM18 4675595 YP_974720.2 CDS trpA NC_008767.1 650051 650836 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 650051..650836 Neisseria meningitidis FAM18 4675599 YP_974721.2 CDS accD NC_008767.1 650873 651745 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 650873..651745 Neisseria meningitidis FAM18 4675189 YP_974722.1 CDS cnp1 NC_008767.1 651805 652428 R hypothetical protein complement(651805..652428) Neisseria meningitidis FAM18 4675426 YP_974723.1 CDS NMC0631 NC_008767.1 652525 652749 D hypothetical protein 652525..652749 Neisseria meningitidis FAM18 4676673 YP_974724.1 CDS NMC0632 NC_008767.1 652750 653355 D lipoprotein 652750..653355 Neisseria meningitidis FAM18 4675590 YP_974725.1 CDS pyrC NC_008767.1 653415 654449 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 653415..654449 Neisseria meningitidis FAM18 4675604 YP_974726.1 CDS nusB NC_008767.1 654813 655238 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(654813..655238) Neisseria meningitidis FAM18 4675791 YP_974727.1 CDS ribH NC_008767.1 655316 655792 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(655316..655792) Neisseria meningitidis FAM18 4676183 YP_974728.1 CDS NMC0636 NC_008767.1 655839 656162 R hypothetical protein complement(655839..656162) Neisseria meningitidis FAM18 4675540 YP_974729.1 CDS rnc NC_008767.1 656245 657048 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 656245..657048 Neisseria meningitidis FAM18 4675618 YP_974730.1 CDS era NC_008767.1 657095 658018 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 657095..658018 Neisseria meningitidis FAM18 4675579 YP_974731.1 CDS trpF NC_008767.1 659053 659679 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(659053..659679) Neisseria meningitidis FAM18 4675888 YP_974732.1 CDS greB NC_008767.1 659738 660229 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB complement(659738..660229) Neisseria meningitidis FAM18 4674828 YP_974733.1 CDS purF NC_008767.1 660329 661873 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(660329..661873) Neisseria meningitidis FAM18 4676480 YP_974734.1 CDS NMC0642 NC_008767.1 662185 662682 R hypothetical protein complement(662185..662682) Neisseria meningitidis FAM18 4675368 YP_974735.1 CDS tpc NC_008767.1 662675 663673 R tetrapac protein complement(662675..663673) Neisseria meningitidis FAM18 4675607 YP_974736.1 CDS folC NC_008767.1 663686 664960 R bifunctional folylpolyglutamate synthase/dihydrofolate synthase complement(663686..664960) Neisseria meningitidis FAM18 4674845 YP_974737.1 CDS folI NC_008767.1 664992 665432 R transcriptional regulator complement(664992..665432) Neisseria meningitidis FAM18 4676705 YP_974738.1 CDS NMC0646 NC_008767.1 665437 665811 R hypothetical protein complement(665437..665811) Neisseria meningitidis FAM18 4676700 YP_974739.1 CDS NMC0647 NC_008767.1 665869 666618 R amino acid permease complement(665869..666618) Neisseria meningitidis FAM18 4675608 YP_974740.1 CDS ksgA NC_008767.1 666770 667549 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(666770..667549) Neisseria meningitidis FAM18 4675565 YP_974741.1 CDS NMC0649 NC_008767.1 667740 668456 D hypothetical protein 667740..668456 Neisseria meningitidis FAM18 4676420 YP_974742.1 CDS trpB NC_008767.1 668641 669843 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 668641..669843 Neisseria meningitidis FAM18 4675658 YP_974743.1 CDS iga NC_008767.1 670022 674728 R IgA1 protease complement(670022..674728) Neisseria meningitidis FAM18 4675190 YP_974744.1 CDS comA NC_008767.1 676012 678087 D competence protein 676012..678087 Neisseria meningitidis FAM18 4676411 YP_974745.1 CDS comL NC_008767.1 678145 678948 R competence lipoprotein complement(678145..678948) Neisseria meningitidis FAM18 4676585 YP_974746.1 CDS rluD NC_008767.1 678947 680071 D ribosomal large subunit pseudouridine synthase D 678947..680071 Neisseria meningitidis FAM18 4676586 YP_974747.1 CDS NMC0655 NC_008767.1 680223 681215 R transmembrane transport protein complement(680223..681215) Neisseria meningitidis FAM18 4675594 YP_974748.1 CDS NMC0656 NC_008767.1 681777 682556 D hypothetical protein 681777..682556 Neisseria meningitidis FAM18 4675626 YP_974749.1 CDS NMC0657 NC_008767.1 682608 683087 D lipoprotein 682608..683087 Neisseria meningitidis FAM18 4676683 YP_974750.1 CDS holA NC_008767.1 683089 684087 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 683089..684087 Neisseria meningitidis FAM18 4676532 YP_974751.1 CDS NMC0659 NC_008767.1 684208 684627 D hypothetical protein 684208..684627 Neisseria meningitidis FAM18 4676435 YP_974752.1 CDS NMC0660 NC_008767.1 684652 685218 D hypothetical protein 684652..685218 Neisseria meningitidis FAM18 4676523 YP_974753.1 CDS NMC0661 NC_008767.1 685302 686186 R hypothetical protein complement(685302..686186) Neisseria meningitidis FAM18 4675814 YP_974754.1 CDS rpoH NC_008767.1 686670 687542 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(686670..687542) Neisseria meningitidis FAM18 4675823 YP_974755.1 CDS lnt NC_008767.1 687797 689341 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(687797..689341) Neisseria meningitidis FAM18 4675316 YP_974756.1 CDS NMC0665 NC_008767.1 689375 690130 R hypothetical protein complement(689375..690130) Neisseria meningitidis FAM18 4676383 YP_974757.1 CDS NMC0666 NC_008767.1 690326 690646 D hypothetical protein 690326..690646 Neisseria meningitidis FAM18 4676663 YP_974758.1 CDS NMC0667 NC_008767.1 690799 691089 D hypothetical protein 690799..691089 Neisseria meningitidis FAM18 4675724 YP_974759.1 CDS NMC0668 NC_008767.1 691152 691553 R cytochrome C complement(691152..691553) Neisseria meningitidis FAM18 4675836 YP_974760.1 CDS hemH NC_008767.1 691745 692755 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(691745..692755) Neisseria meningitidis FAM18 4675731 YP_974761.1 CDS tgt NC_008767.1 692837 693952 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(692837..693952) Neisseria meningitidis FAM18 4676500 YP_974762.1 CDS thrS NC_008767.1 694227 696173 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 694227..696173 Neisseria meningitidis FAM18 4675203 YP_974763.1 CDS infC NC_008767.1 696191 696712 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 696191..696712 Neisseria meningitidis FAM18 4675195 YP_974764.1 CDS rpmI NC_008767.1 696859 697056 D 50S ribosomal protein L35 696859..697056 Neisseria meningitidis FAM18 4676433 YP_974765.1 CDS rplT NC_008767.1 697069 697428 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 697069..697428 Neisseria meningitidis FAM18 4675730 YP_974766.2 CDS pheS NC_008767.1 697774 698766 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 697774..698766 Neisseria meningitidis FAM18 4675372 YP_974767.1 CDS vsr NC_008767.1 699090 699536 D NmeDIP very-short-patch-repair endonuclease 699090..699536 Neisseria meningitidis FAM18 4676112 YP_974768.1 CDS nmeDIMP NC_008767.1 699550 700701 D modification methylase NmeDI 699550..700701 Neisseria meningitidis FAM18 4676707 YP_974769.1 CDS NMC0680 NC_008767.1 700673 701728 D type II restriction enzyme NmeDIP 700673..701728 Neisseria meningitidis FAM18 4676227 YP_974770.1 CDS pheT NC_008767.1 701783 704146 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 701783..704146 Neisseria meningitidis FAM18 4675727 YP_974771.1 CDS ihfA NC_008767.1 704220 704522 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 704220..704522 Neisseria meningitidis FAM18 4676122 YP_974772.1 CDS NMC0683 NC_008767.1 704524 704814 D hypothetical protein 704524..704814 Neisseria meningitidis FAM18 4676467 YP_974773.1 CDS fxsA NC_008767.1 705144 705629 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 705144..705629 Neisseria meningitidis FAM18 4675743 YP_974774.1 CDS bioA NC_008767.1 706341 707642 D adenosylmethionine-8-amino-7-oxononanoate aminotransferase 706341..707642 Neisseria meningitidis FAM18 4675756 YP_974775.1 CDS bioD NC_008767.1 707639 708286 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 707639..708286 Neisseria meningitidis FAM18 4676626 YP_974776.1 CDS NMC0687 NC_008767.1 708253 708777 D hypothetical protein 708253..708777 Neisseria meningitidis FAM18 4676554 YP_974777.1 CDS ubiA NC_008767.1 708807 709697 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 708807..709697 Neisseria meningitidis FAM18 4675755 YP_974778.1 CDS NMC0689 NC_008767.1 709882 710331 D regulatory protein 709882..710331 Neisseria meningitidis FAM18 4676208 YP_974779.1 CDS NMC0690 NC_008767.1 710335 711297 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 710335..711297 Neisseria meningitidis FAM18 4675781 YP_974780.1 CDS NMC0691 NC_008767.1 711278 712132 D hypothetical protein 711278..712132 Neisseria meningitidis FAM18 4675784 YP_974781.1 CDS rbgA NC_008767.1 712213 713154 D essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 712213..713154 Neisseria meningitidis FAM18 4675776 YP_974782.1 CDS NMC0693 NC_008767.1 713255 713857 D hypothetical protein 713255..713857 Neisseria meningitidis FAM18 4675789 YP_974783.1 CDS recN NC_008767.1 714041 715714 D DNA repair protein 714041..715714 Neisseria meningitidis FAM18 4675804 YP_974784.1 CDS NMC0695 NC_008767.1 716796 718415 R hypothetical protein complement(716796..718415) Neisseria meningitidis FAM18 4675749 YP_974785.1 CDS NMC0696 NC_008767.1 718535 718903 D hypothetical protein 718535..718903 Neisseria meningitidis FAM18 4675797 YP_974786.1 CDS ubiE NC_008767.1 718946 719683 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 718946..719683 Neisseria meningitidis FAM18 4675948 YP_974787.1 CDS NMC0698 NC_008767.1 719903 720382 D hypothetical protein 719903..720382 Neisseria meningitidis FAM18 4676209 YP_974788.1 CDS folK NC_008767.1 720507 721001 R 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine- pyrophosphokinase complement(720507..721001) Neisseria meningitidis FAM18 4675945 YP_974789.1 CDS NMC0700 NC_008767.1 721011 721385 R regulator complement(721011..721385) Neisseria meningitidis FAM18 4676686 YP_974790.1 CDS NMC0701 NC_008767.1 721439 722005 R hypothetical protein complement(721439..722005) Neisseria meningitidis FAM18 4675830 YP_974791.1 CDS hfq NC_008767.1 722089 722382 R regulator complement(722089..722382) Neisseria meningitidis FAM18 4675902 YP_974792.1 CDS NMC0703 NC_008767.1 722511 723461 R D-alanyl-D-alanine-endopeptidase complement(722511..723461) Neisseria meningitidis FAM18 4675852 YP_974793.1 CDS NMC0704 NC_008767.1 723707 724210 D hypothetical protein 723707..724210 Neisseria meningitidis FAM18 4675146 YP_974794.1 CDS xerD NC_008767.1 724262 725137 D integrase/recombinase 724262..725137 Neisseria meningitidis FAM18 4675920 YP_974795.1 CDS NMC0706 NC_008767.1 725309 725509 D ferredoxin 725309..725509 Neisseria meningitidis FAM18 4676681 YP_974796.1 CDS NMC0707 NC_008767.1 725675 725908 D thioredoxin 725675..725908 Neisseria meningitidis FAM18 4675913 YP_974797.1 CDS rfbD NC_008767.1 726383 727246 R dTDP-4-dehydrorhamnose reductase complement(726383..727246) Neisseria meningitidis FAM18 4675884 YP_974798.1 CDS purC NC_008767.1 727259 728308 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 727259..728308 Neisseria meningitidis FAM18 4675542 YP_974799.1 CDS pnp NC_008767.1 728530 730665 D polynucleotide phosphorylase 728530..730665 Neisseria meningitidis FAM18 4676023 YP_974800.1 CDS NMC0711 NC_008767.1 730737 731405 R hypothetical protein complement(730737..731405) Neisseria meningitidis FAM18 4675954 YP_974801.1 CDS NMC0712 NC_008767.1 731419 731739 R lipoprotein complement(731419..731739) Neisseria meningitidis FAM18 4675880 YP_974802.1 CDS dapF NC_008767.1 731852 732703 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 731852..732703 Neisseria meningitidis FAM18 4675154 YP_974803.1 CDS NMC0714 NC_008767.1 732700 733305 D hypothetical protein 732700..733305 Neisseria meningitidis FAM18 4676001 YP_974804.1 CDS cysK NC_008767.1 733445 734431 D cysteine synthase 733445..734431 Neisseria meningitidis FAM18 4675856 YP_974805.1 CDS NMC0717 NC_008767.1 734868 735848 D hypothetical protein 734868..735848 Neisseria meningitidis FAM18 4676021 YP_974806.1 CDS lepB NC_008767.1 736262 737281 R signal peptidase I complement(736262..737281) Neisseria meningitidis FAM18 4675870 YP_974807.1 CDS lepA NC_008767.1 737424 739217 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(737424..739217) Neisseria meningitidis FAM18 4676398 YP_974808.1 CDS pfs NC_008767.1 739360 740115 R 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(739360..740115) Neisseria meningitidis FAM18 4676408 YP_974809.1 CDS pilT2 NC_008767.1 740247 741359 D pilus retraction protein 740247..741359 Neisseria meningitidis FAM18 4676150 YP_974810.1 CDS holB NC_008767.1 741394 742371 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 741394..742371 Neisseria meningitidis FAM18 4676032 YP_974811.1 CDS NMC0723 NC_008767.1 742375 742725 D pilus biogenesis protein 742375..742725 Neisseria meningitidis FAM18 4676436 YP_974812.1 CDS NMC0724 NC_008767.1 742730 743509 D hypothetical protein 742730..743509 Neisseria meningitidis FAM18 4675153 YP_974813.1 CDS NMC0726 NC_008767.1 743851 744162 D hypothetical protein 743851..744162 Neisseria meningitidis FAM18 4676708 YP_974814.1 CDS upp NC_008767.1 744268 744894 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 744268..744894 Neisseria meningitidis FAM18 4674744 YP_974815.1 CDS NMC0728 NC_008767.1 744917 745237 D hypothetical protein 744917..745237 Neisseria meningitidis FAM18 4676475 YP_974816.1 CDS NMC0729 NC_008767.1 745640 746062 D secreted protein 745640..746062 Neisseria meningitidis FAM18 4676518 YP_974817.1 CDS hemD NC_008767.1 746089 746841 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 746089..746841 Neisseria meningitidis FAM18 4676505 YP_974818.1 CDS NMC0731 NC_008767.1 746856 748190 D hypothetical protein 746856..748190 Neisseria meningitidis FAM18 4676674 YP_974819.1 CDS NMC0732 NC_008767.1 748187 749404 D hypothetical protein 748187..749404 Neisseria meningitidis FAM18 4676697 YP_974820.1 CDS hemE NC_008767.1 749479 750543 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 749479..750543 Neisseria meningitidis FAM18 4676623 YP_974821.1 CDS radA NC_008767.1 750706 752100 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 750706..752100 Neisseria meningitidis FAM18 4676499 YP_974822.1 CDS NMC0735 NC_008767.1 752375 752854 R hypothetical protein complement(752375..752854) Neisseria meningitidis FAM18 4675772 YP_974823.1 CDS NMC0736 NC_008767.1 752986 753429 R hypothetical protein complement(752986..753429) Neisseria meningitidis FAM18 4676511 YP_974824.1 CDS recB NC_008767.1 753384 756998 R exodeoxyribonuclease V subunit beta complement(753384..756998) Neisseria meningitidis FAM18 4675668 YP_974825.1 CDS NMC0738 NC_008767.1 757231 758349 R hypothetical protein complement(757231..758349) Neisseria meningitidis FAM18 4675753 YP_974826.1 CDS NMC0739 NC_008767.1 758424 759251 D amino acid permease 758424..759251 Neisseria meningitidis FAM18 4676415 YP_974827.1 CDS NMC0741 NC_008767.1 759241 759957 D amino acid permease 759241..759957 Neisseria meningitidis FAM18 4676445 YP_974828.1 CDS NMC0742 NC_008767.1 759967 760722 D amino acid permease 759967..760722 Neisseria meningitidis FAM18 4676386 YP_974829.1 CDS pgm NC_008767.1 760742 762124 R phosphoglucomutase complement(760742..762124) Neisseria meningitidis FAM18 4676409 YP_974830.1 CDS ppiB NC_008767.1 762287 762796 R peptidyl-prolyl cis-trans isomerase B complement(762287..762796) Neisseria meningitidis FAM18 4676131 YP_974831.1 CDS NMC0745 NC_008767.1 762915 764330 R transmembrane transport protein complement(762915..764330) Neisseria meningitidis FAM18 4676075 YP_974832.1 CDS NMC0746 NC_008767.1 764561 764884 R hypothetical protein complement(764561..764884) Neisseria meningitidis FAM18 4676361 YP_974833.1 CDS pth NC_008767.1 765187 765765 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(765187..765765) Neisseria meningitidis FAM18 4674745 YP_974834.1 CDS NMC0748 NC_008767.1 765818 766096 R hypothetical protein complement(765818..766096) Neisseria meningitidis FAM18 4675985 YP_974835.1 CDS NMC0749 NC_008767.1 766089 766532 R hypothetical protein complement(766089..766532) Neisseria meningitidis FAM18 4676333 YP_974836.1 CDS ftsH NC_008767.1 766741 768708 R ATP-dependent zinc metallopeptidase complement(766741..768708) Neisseria meningitidis FAM18 4676271 YP_974837.1 CDS ftsJ NC_008767.1 768772 769392 R cell division protein complement(768772..769392) Neisseria meningitidis FAM18 4676658 YP_974838.1 CDS NMC0752 NC_008767.1 769466 769786 D hypothetical protein 769466..769786 Neisseria meningitidis FAM18 4676649 YP_974839.1 CDS hemB NC_008767.1 769954 770970 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 769954..770970 Neisseria meningitidis FAM18 4676278 YP_974840.1 CDS NMC0754 NC_008767.1 771033 772259 R carbon-sulfur lyase complement(771033..772259) Neisseria meningitidis FAM18 4676350 YP_974841.2 CDS NMC0755 NC_008767.1 772382 773155 D similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase 772382..773155 Neisseria meningitidis FAM18 4676233 YP_974842.1 CDS NMC0756 NC_008767.1 773355 774020 D NAD(P)H-flavin oxidoreductase 773355..774020 Neisseria meningitidis FAM18 4676210 YP_974843.1 CDS NMC0757 NC_008767.1 774075 774833 R RNA-binding protein complement(774075..774833) Neisseria meningitidis FAM18 4676228 YP_974844.1 CDS ppnK NC_008767.1 774858 775748 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(774858..775748) Neisseria meningitidis FAM18 4676009 YP_974845.1 CDS NMC0759 NC_008767.1 775768 776334 R hypothetical protein complement(775768..776334) Neisseria meningitidis FAM18 4676189 YP_974846.1 CDS NMC0760 NC_008767.1 776385 777161 R hypothetical protein complement(776385..777161) Neisseria meningitidis FAM18 4676136 YP_974847.1 CDS NMC0761 NC_008767.1 777216 777866 R TetR family transcriptional regulator complement(777216..777866) Neisseria meningitidis FAM18 4676145 YP_974848.1 CDS murB NC_008767.1 777878 778918 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(777878..778918) Neisseria meningitidis FAM18 4676008 YP_974849.1 CDS NMC0763 NC_008767.1 779097 780476 R NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein complement(779097..780476) Neisseria meningitidis FAM18 4676268 YP_974850.1 CDS hisZ NC_008767.1 780811 781962 D May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase 780811..781962 Neisseria meningitidis FAM18 4676036 YP_974851.1 CDS purA NC_008767.1 782060 783364 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 782060..783364 Neisseria meningitidis FAM18 4676096 YP_974852.1 CDS htpX NC_008767.1 783751 784590 R metalloprotease; heat shock protein HtpX complement(783751..784590) Neisseria meningitidis FAM18 4675798 YP_974853.1 CDS adk NC_008767.1 784805 785452 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 784805..785452 Neisseria meningitidis FAM18 4676454 YP_974854.1 CDS pyrF NC_008767.1 785978 786718 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 785978..786718 Neisseria meningitidis FAM18 4675505 YP_974855.1 CDS rfaE NC_008767.1 786773 787744 D DP-heptose synthetase 786773..787744 Neisseria meningitidis FAM18 4675777 YP_974856.1 CDS nmgII NC_008767.1 787781 789016 D deleted EC_number 2.1.1.73; modification methylase 787781..789016 Neisseria meningitidis FAM18 4675732 YP_974857.1 CDS nmgI NC_008767.1 789018 790136 D type II restriction endonuclease 789018..790136 Neisseria meningitidis FAM18 4675952 YP_974858.1 CDS rfaD NC_008767.1 790177 791181 D ADP-L-glycero-D-manno-heptose-6-epimerase 790177..791181 Neisseria meningitidis FAM18 4675951 YP_974859.1 CDS clpA NC_008767.1 791245 793560 R ATP-dependent protease ATP-binding protein complement(791245..793560) Neisseria meningitidis FAM18 4675726 YP_974860.1 CDS clpS NC_008767.1 793544 793846 R involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS complement(793544..793846) Neisseria meningitidis FAM18 4676694 YP_974861.1 CDS cspA NC_008767.1 794089 794292 D transcriptional regulator 794089..794292 Neisseria meningitidis FAM18 4676115 YP_974862.1 CDS NMC0777 NC_008767.1 794589 795920 R hypothetical protein complement(794589..795920) Neisseria meningitidis FAM18 4676615 YP_974863.1 CDS NMC0778 NC_008767.1 796063 796581 D hypothetical protein 796063..796581 Neisseria meningitidis FAM18 4675712 YP_974864.1 CDS NMC0779 NC_008767.1 796616 797362 D hypothetical protein 796616..797362 Neisseria meningitidis FAM18 4675717 YP_974865.1 CDS recJ NC_008767.1 797414 799114 D single-stranded-DNA-specific exonuclease 797414..799114 Neisseria meningitidis FAM18 4675700 YP_974866.1 CDS pcnB NC_008767.1 799483 800829 D poly(A) polymerase 799483..800829 Neisseria meningitidis FAM18 4675748 YP_974867.1 CDS NMC0782 NC_008767.1 800974 801300 D hypothetical protein 800974..801300 Neisseria meningitidis FAM18 4676134 YP_974868.1 CDS NMC0784 NC_008767.1 801404 802357 R hypothetical protein complement(801404..802357) Neisseria meningitidis FAM18 4675683 YP_974869.1 CDS NMC0788 NC_008767.1 803887 804591 D hypothetical protein 803887..804591 Neisseria meningitidis FAM18 4675689 YP_974870.1 CDS dcd NC_008767.1 804655 805221 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(804655..805221) Neisseria meningitidis FAM18 4675694 YP_974871.1 CDS NMC0790 NC_008767.1 805287 805703 R hypothetical protein complement(805287..805703) Neisseria meningitidis FAM18 4675682 YP_974872.1 CDS rdgC NC_008767.1 805765 806664 R Required for efficient pilin antigenic variation; recombination associated protein complement(805765..806664) Neisseria meningitidis FAM18 4675684 YP_974873.1 CDS engA NC_008767.1 806695 808152 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(806695..808152) Neisseria meningitidis FAM18 4675763 YP_974874.1 CDS NMC0793 NC_008767.1 808302 808931 R hypothetical protein complement(808302..808931) Neisseria meningitidis FAM18 4675676 YP_974875.1 CDS hisS NC_008767.1 808932 810227 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(808932..810227) Neisseria meningitidis FAM18 4675679 YP_974876.1 CDS NMC0795 NC_008767.1 810354 811019 R hypothetical protein complement(810354..811019) Neisseria meningitidis FAM18 4676342 YP_974877.1 CDS NMC0796 NC_008767.1 811292 811828 R hypothetical protein complement(811292..811828) Neisseria meningitidis FAM18 4675681 YP_974878.1 CDS NMC0798 NC_008767.1 811996 812196 R hypothetical protein complement(811996..812196) Neisseria meningitidis FAM18 4675659 YP_974879.1 CDS NMC0800 NC_008767.1 812788 813153 R hypothetical protein complement(812788..813153) Neisseria meningitidis FAM18 4675662 YP_974880.1 CDS NMC0801 NC_008767.1 813135 813680 R hypothetical protein complement(813135..813680) Neisseria meningitidis FAM18 4675552 YP_974881.1 CDS NMC0802 NC_008767.1 813843 814139 R hypothetical protein complement(813843..814139) Neisseria meningitidis FAM18 4675553 YP_974882.1 CDS NMC0803 NC_008767.1 814381 814671 R hypothetical protein complement(814381..814671) Neisseria meningitidis FAM18 4675557 YP_974883.1 CDS NMC0804 NC_008767.1 814991 815239 R hypothetical protein complement(814991..815239) Neisseria meningitidis FAM18 4675536 YP_974884.1 CDS NMC0805 NC_008767.1 815285 815653 R hypothetical protein complement(815285..815653) Neisseria meningitidis FAM18 4675515 YP_974885.1 CDS NMC0806 NC_008767.1 815999 816394 R hypothetical protein complement(815999..816394) Neisseria meningitidis FAM18 4675556 YP_974886.1 CDS NMC0807 NC_008767.1 816437 817306 R hypothetical protein complement(816437..817306) Neisseria meningitidis FAM18 4675424 YP_974887.1 CDS NMC0808 NC_008767.1 817471 818394 D hypothetical protein 817471..818394 Neisseria meningitidis FAM18 4675404 YP_974888.1 CDS NMC0809 NC_008767.1 818472 819113 R hypothetical protein complement(818472..819113) Neisseria meningitidis FAM18 4675413 YP_974889.1 CDS NMC0810 NC_008767.1 819168 819959 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(819168..819959) Neisseria meningitidis FAM18 4675420 YP_974890.1 CDS panB NC_008767.1 820452 821243 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 820452..821243 Neisseria meningitidis FAM18 4675383 YP_974891.1 CDS panC NC_008767.1 821366 822202 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 821366..822202 Neisseria meningitidis FAM18 4675973 YP_974892.1 CDS NMC0813 NC_008767.1 822361 824211 D hypothetical protein 822361..824211 Neisseria meningitidis FAM18 4675974 YP_974893.1 CDS lolB NC_008767.1 824294 824932 D Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 824294..824932 Neisseria meningitidis FAM18 4675380 YP_974894.1 CDS ipk NC_008767.1 824942 825787 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 824942..825787 Neisseria meningitidis FAM18 4675392 YP_974895.1 CDS prsA NC_008767.1 826205 827188 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 826205..827188 Neisseria meningitidis FAM18 4675379 YP_974896.1 CDS NMC0817 NC_008767.1 827255 827827 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 827255..827827 Neisseria meningitidis FAM18 4676028 YP_974897.1 CDS NMC0818 NC_008767.1 827952 829121 R D-alanyl-D-alanine carboxypeptidase complement(827952..829121) Neisseria meningitidis FAM18 4675377 YP_974898.1 CDS ilvA NC_008767.1 829269 830795 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 829269..830795 Neisseria meningitidis FAM18 4675376 YP_974899.1 CDS cysA NC_008767.1 830852 831925 R sulfate permease ATP-binding protein complement(830852..831925) Neisseria meningitidis FAM18 4676441 YP_974900.1 CDS cysW NC_008767.1 831922 832782 R sulfate permease inner membrane protein complement(831922..832782) Neisseria meningitidis FAM18 4675813 YP_974901.1 CDS cysU NC_008767.1 833037 833873 R sulfate permease inner membrane protein complement(833037..833873) Neisseria meningitidis FAM18 4675995 YP_974902.1 CDS NMC0823 NC_008767.1 834164 834496 D hypothetical protein 834164..834496 Neisseria meningitidis FAM18 4676020 YP_974903.1 CDS NMC0824 NC_008767.1 834827 835336 D hypothetical protein 834827..835336 Neisseria meningitidis FAM18 4675365 YP_974904.1 CDS sodB NC_008767.1 835908 836495 R superoxide dismutase complement(835908..836495) Neisseria meningitidis FAM18 4675296 YP_974905.1 CDS dnaB NC_008767.1 836658 838064 D unwinds double stranded DNA; replicative DNA helicase 836658..838064 Neisseria meningitidis FAM18 4675031 YP_974906.1 CDS NMC0827 NC_008767.1 838328 839047 D hypothetical protein 838328..839047 Neisseria meningitidis FAM18 4675940 YP_974907.1 CDS NMC0828 NC_008767.1 839065 839682 D hypothetical protein 839065..839682 Neisseria meningitidis FAM18 4675293 YP_974908.1 CDS NMC0829 NC_008767.1 839679 840620 D hypothetical protein 839679..840620 Neisseria meningitidis FAM18 4675289 YP_974909.1 CDS NMC0830 NC_008767.1 840599 841198 D hypothetical protein 840599..841198 Neisseria meningitidis FAM18 4675288 YP_974910.1 CDS NMC0831 NC_008767.1 841188 841676 D pilin 841188..841676 Neisseria meningitidis FAM18 4675285 YP_974911.1 CDS NMC0832 NC_008767.1 843353 843835 R hypothetical protein complement(843353..843835) Neisseria meningitidis FAM18 4675283 YP_974912.1 CDS dut NC_008767.1 843948 844430 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 843948..844430 Neisseria meningitidis FAM18 4675279 YP_974913.1 CDS NMC0834 NC_008767.1 844506 845693 D catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate; succinyldiaminopimelate transaminase 844506..845693 Neisseria meningitidis FAM18 4675929 YP_974914.1 CDS NMC0835 NC_008767.1 845955 846734 D hypothetical protein 845955..846734 Neisseria meningitidis FAM18 4675265 YP_974915.1 CDS NMC0836 NC_008767.1 847266 848462 D Phage integrase 847266..848462 Neisseria meningitidis FAM18 4675264 YP_974916.1 CDS NMC0837 NC_008767.1 848617 848997 D hypothetical protein 848617..848997 Neisseria meningitidis FAM18 4675263 YP_974917.1 CDS NMC0838 NC_008767.1 849043 849231 D hypothetical protein 849043..849231 Neisseria meningitidis FAM18 4675262 YP_974918.1 CDS NMC0839 NC_008767.1 849556 849912 D hypothetical protein 849556..849912 Neisseria meningitidis FAM18 4675261 YP_974919.1 CDS NMC0840 NC_008767.1 850780 851697 D phage related protein 850780..851697 Neisseria meningitidis FAM18 4675260 YP_974920.1 CDS NMC0841 NC_008767.1 851755 852039 R D-lactate dehydrogenase-like protein complement(851755..852039) Neisseria meningitidis FAM18 4675274 YP_974921.1 CDS NMC0842 NC_008767.1 852101 852292 R hypothetical protein complement(852101..852292) Neisseria meningitidis FAM18 4675133 YP_974922.1 CDS NMC0843 NC_008767.1 852295 852588 R hypothetical protein complement(852295..852588) Neisseria meningitidis FAM18 4675131 YP_974923.1 CDS NMC0844 NC_008767.1 852585 852845 R coiled coil, 39-60; lipoprotein complement(852585..852845) Neisseria meningitidis FAM18 4675130 YP_974924.1 CDS NMC0845 NC_008767.1 852881 853096 R hypothetical protein complement(852881..853096) Neisseria meningitidis FAM18 4675126 YP_974925.1 CDS NMC0846 NC_008767.1 853168 854022 R hypothetical protein complement(853168..854022) Neisseria meningitidis FAM18 4675125 YP_974926.1 CDS NMC0847 NC_008767.1 854047 854406 R hypothetical protein complement(854047..854406) Neisseria meningitidis FAM18 4675122 YP_974927.1 CDS NMC0848 NC_008767.1 854474 854674 R hypothetical protein complement(854474..854674) Neisseria meningitidis FAM18 4675119 YP_974928.1 CDS NMC0849 NC_008767.1 854905 855429 R hypothetical protein complement(854905..855429) Neisseria meningitidis FAM18 4675071 YP_974929.1 CDS NMC0850 NC_008767.1 855433 856149 R transcriptional regulator complement(855433..856149) Neisseria meningitidis FAM18 4675069 YP_974930.1 CDS NMC0852 NC_008767.1 856549 856896 D coiled coil, 56-83; hypothetical protein 856549..856896 Neisseria meningitidis FAM18 4675066 YP_974931.1 CDS NMC0853 NC_008767.1 857011 859857 D hypothetical protein 857011..859857 Neisseria meningitidis FAM18 4675065 YP_974932.1 CDS NMC0854 NC_008767.1 859874 860083 D hypothetical protein 859874..860083 Neisseria meningitidis FAM18 4675054 YP_974933.1 CDS NMC0855 NC_008767.1 860086 860472 D hypothetical protein 860086..860472 Neisseria meningitidis FAM18 4675048 YP_974934.1 CDS NMC0856 NC_008767.1 860459 860713 D coiled coil, 50-61; hypothetical protein 860459..860713 Neisseria meningitidis FAM18 4675041 YP_974935.1 CDS NMC0857 NC_008767.1 860722 862284 D phage related protein 860722..862284 Neisseria meningitidis FAM18 4675027 YP_974936.1 CDS NMC0858 NC_008767.1 862274 864157 D phage-like protein 862274..864157 Neisseria meningitidis FAM18 4674916 YP_974937.1 CDS NMC0859 NC_008767.1 864215 864442 D hypothetical protein 864215..864442 Neisseria meningitidis FAM18 4674910 YP_974938.1 CDS NMC0860 NC_008767.1 864435 864737 D hypothetical protein 864435..864737 Neisseria meningitidis FAM18 4674906 YP_974939.1 CDS NMC0861 NC_008767.1 864760 865137 D hypothetical protein 864760..865137 Neisseria meningitidis FAM18 4674893 YP_974940.1 CDS NMC0862 NC_008767.1 865169 865810 D hypothetical protein 865169..865810 Neisseria meningitidis FAM18 4674884 YP_974941.1 CDS NMC0863 NC_008767.1 865874 866185 D hypothetical protein 865874..866185 Neisseria meningitidis FAM18 4674882 YP_974942.1 CDS NMC0864 NC_008767.1 866233 866505 D hypothetical protein 866233..866505 Neisseria meningitidis FAM18 4674873 YP_974943.1 CDS NMC0865 NC_008767.1 866498 869716 D coiled coils, 60-70, 429-480, 760-775; prophage-like protein 866498..869716 Neisseria meningitidis FAM18 4674840 YP_974944.1 CDS NMC0866 NC_008767.1 869738 870007 D phage-like protein 869738..870007 Neisseria meningitidis FAM18 4674830 YP_974945.1 CDS NMC0867 NC_008767.1 870067 870789 D phage-like protein 870067..870789 Neisseria meningitidis FAM18 4674794 YP_974946.1 CDS NMC0868 NC_008767.1 870786 871541 D phage-like protein NLPC_P60 870786..871541 Neisseria meningitidis FAM18 4674765 YP_974947.1 CDS NMC0869 NC_008767.1 871538 872260 D phage-like protein 871538..872260 Neisseria meningitidis FAM18 4676698 YP_974948.1 CDS NMC0870 NC_008767.1 872396 876661 D coiled coils, 800-880, 1120-1146; hypothetical protein 872396..876661 Neisseria meningitidis FAM18 4675159 YP_974949.1 CDS NMC0871 NC_008767.1 876732 877178 D hypothetical protein 876732..877178 Neisseria meningitidis FAM18 4675164 YP_974950.1 CDS NMC0872 NC_008767.1 877195 877401 D hypothetical protein 877195..877401 Neisseria meningitidis FAM18 4675177 YP_974951.1 CDS NMC0873 NC_008767.1 877430 877840 D hypothetical protein 877430..877840 Neisseria meningitidis FAM18 4675181 YP_974952.1 CDS NMC0877 NC_008767.1 878740 879213 D ATP binding protein 878740..879213 Neisseria meningitidis FAM18 4675175 YP_974953.1 CDS NMC0878 NC_008767.1 879225 879734 D coiled coil, 60-100; hypothetical protein 879225..879734 Neisseria meningitidis FAM18 4674757 YP_974954.1 CDS NMC0879 NC_008767.1 879787 880134 R plamid toxin PemK protein complement(879787..880134) Neisseria meningitidis FAM18 4675234 YP_974955.1 CDS NMC0880 NC_008767.1 880136 880372 R transcriptional regulator complement(880136..880372) Neisseria meningitidis FAM18 4675443 YP_974956.1 CDS NMC0881 NC_008767.1 880731 881381 R hypothetical protein complement(880731..881381) Neisseria meningitidis FAM18 4675359 YP_974957.1 CDS NMC0882 NC_008767.1 881660 882028 R death-on-curing protein, prophage related protein complement(881660..882028) Neisseria meningitidis FAM18 4675232 YP_974958.1 CDS NMC0883 NC_008767.1 882025 882183 R hypothetical protein complement(882025..882183) Neisseria meningitidis FAM18 4675233 YP_974959.1 CDS NMC0884 NC_008767.1 882572 883579 R transposase for IS1106A3 complement(882572..883579) Neisseria meningitidis FAM18 4675136 YP_974960.1 CDS NMC0887 NC_008767.1 884729 885991 R HlyD family secretion protein complement(884729..885991) Neisseria meningitidis FAM18 4675235 YP_974961.1 CDS NMC0888 NC_008767.1 885993 888089 R ABC transporter complement(885993..888089) Neisseria meningitidis FAM18 4675237 YP_974962.1 CDS NMC0889 NC_008767.1 888125 888460 R hypothetical protein complement(888125..888460) Neisseria meningitidis FAM18 4675251 YP_974963.1 CDS NMC0890 NC_008767.1 888453 888872 R hypothetical protein complement(888453..888872) Neisseria meningitidis FAM18 4675250 YP_974964.1 CDS NMC0891 NC_008767.1 888876 890024 R hypothetical protein complement(888876..890024) Neisseria meningitidis FAM18 4676065 YP_974965.1 CDS NMC0892 NC_008767.1 890118 890234 D hypothetical protein 890118..890234 Neisseria meningitidis FAM18 4675243 YP_974966.1 CDS NMC0893 NC_008767.1 890200 890403 R ParB protein complement(890200..890403) Neisseria meningitidis FAM18 4676056 YP_974967.1 CDS parA NC_008767.1 890446 891090 R ParA protein complement(join(890446..890865,890869..891090)) Neisseria meningitidis FAM18 4675299 YP_974968.1 CDS NMC0896 NC_008767.1 891437 892411 R fragment due to substitution of M->S; transposase for IS1106A3 (fragment) complement(891437..892411) Neisseria meningitidis FAM18 4676180 YP_974969.1 CDS icd NC_008767.1 893798 896023 R isocitrate dehydrogenase complement(893798..896023) Neisseria meningitidis FAM18 4675242 YP_974970.1 CDS lst NC_008767.1 896456 897571 D CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 896456..897571 Neisseria meningitidis FAM18 4676410 YP_974971.1 CDS NMC0900 NC_008767.1 897736 898194 R cytochrome C complement(897736..898194) Neisseria meningitidis FAM18 4676338 YP_974972.1 CDS NMC0901 NC_008767.1 898313 899134 D oxidoreductase 898313..899134 Neisseria meningitidis FAM18 4676128 YP_974973.1 CDS NMC0902 NC_008767.1 899185 899631 R acyl-CoA hydrolase complement(899185..899631) Neisseria meningitidis FAM18 4675239 YP_974974.1 CDS opaD NC_008767.1 901047 901833 R hypothetical protein complement(join(901047..901790,901786..901833)) Neisseria meningitidis FAM18 4675311 YP_974975.1 CDS NMC0904 NC_008767.1 902518 903483 R transposase for IS1655 complement(902518..903483) Neisseria meningitidis FAM18 4675537 YP_974976.1 CDS pip NC_008767.1 904126 905061 D proline iminopeptidase 904126..905061 Neisseria meningitidis FAM18 4675315 YP_974977.1 CDS NMC0906 NC_008767.1 905118 906314 R lipoprotein complement(905118..906314) Neisseria meningitidis FAM18 4676089 YP_974978.1 CDS dapA NC_008767.1 906323 907198 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(906323..907198) Neisseria meningitidis FAM18 4675313 YP_974979.1 CDS NMC0908 NC_008767.1 907487 908896 D transmembrane transport protein 907487..908896 Neisseria meningitidis FAM18 4675949 YP_974980.1 CDS NMC0909 NC_008767.1 908958 909710 R RNA methylase complement(908958..909710) Neisseria meningitidis FAM18 4675324 YP_974981.1 CDS NMC0910 NC_008767.1 909776 910264 R hypothetical protein complement(909776..910264) Neisseria meningitidis FAM18 4675323 YP_974982.1 CDS NMC0911 NC_008767.1 910269 910988 R cytosine deaminase complement(910269..910988) Neisseria meningitidis FAM18 4675318 YP_974983.1 CDS miaA NC_008767.1 910992 911933 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(910992..911933) Neisseria meningitidis FAM18 4675325 YP_974984.1 CDS NMC0913 NC_008767.1 912312 913685 R hypothetical protein complement(join(912312..912875,912879..913685)) Neisseria meningitidis FAM18 4676305 YP_974985.1 CDS efp NC_008767.1 913923 914483 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 913923..914483 Neisseria meningitidis FAM18 4675320 YP_974986.1 CDS NMC0916 NC_008767.1 914533 915378 R lipoprotein complement(914533..915378) Neisseria meningitidis FAM18 4675921 YP_974987.1 CDS NMC0917 NC_008767.1 915495 916085 R hypothetical protein complement(915495..916085) Neisseria meningitidis FAM18 4675287 YP_974988.1 CDS metX NC_008767.1 916073 917194 R Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase complement(916073..917194) Neisseria meningitidis FAM18 4675326 YP_974989.1 CDS rpmJ NC_008767.1 917661 917786 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(917661..917786) Neisseria meningitidis FAM18 4676316 YP_974990.1 CDS rpmE2 NC_008767.1 917786 918061 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(917786..918061) Neisseria meningitidis FAM18 4675329 YP_974991.1 CDS metF NC_008767.1 918261 919139 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 918261..919139 Neisseria meningitidis FAM18 4675430 YP_974992.1 CDS metE NC_008767.1 919277 921553 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 919277..921553 Neisseria meningitidis FAM18 4676314 YP_974993.1 CDS NMC0923 NC_008767.1 921832 922569 D redoxin 921832..922569 Neisseria meningitidis FAM18 4676313 YP_974994.1 CDS lpdA2 NC_008767.1 922818 924221 D Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 922818..924221 Neisseria meningitidis FAM18 4675333 YP_974995.1 CDS sdhC NC_008767.1 924500 924877 D succinate dehydrogenase cytochrome B subunit 924500..924877 Neisseria meningitidis FAM18 4676357 YP_974996.1 CDS sdhD NC_008767.1 924886 925212 D succinate dehydrogenase hydrophobic membrane anchor protein 924886..925212 Neisseria meningitidis FAM18 4675110 YP_974997.1 CDS sdhA NC_008767.1 925203 926978 D succinate dehydrogenase flavoprotein subunit 925203..926978 Neisseria meningitidis FAM18 4675102 YP_974998.1 CDS sdhB NC_008767.1 927075 927806 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 927075..927806 Neisseria meningitidis FAM18 4675217 YP_974999.1 CDS NMC0929 NC_008767.1 927810 928058 D hypothetical protein 927810..928058 Neisseria meningitidis FAM18 4675109 YP_975000.1 CDS gltA NC_008767.1 928170 929453 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 928170..929453 Neisseria meningitidis FAM18 4675331 YP_975001.1 CDS sucA NC_008767.1 929658 932486 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 929658..932486 Neisseria meningitidis FAM18 4676576 YP_975002.1 CDS sucB NC_008767.1 932586 933827 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 932586..933827 Neisseria meningitidis FAM18 4675008 YP_975003.1 CDS lpdA3 NC_008767.1 934192 935625 D E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 934192..935625 Neisseria meningitidis FAM18 4674994 YP_975004.1 CDS NMC0934 NC_008767.1 935750 936037 D hypothetical protein 935750..936037 Neisseria meningitidis FAM18 4676334 YP_975005.1 CDS sucC NC_008767.1 936137 937303 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 936137..937303 Neisseria meningitidis FAM18 4675334 YP_975006.1 CDS sucD NC_008767.1 937314 938204 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 937314..938204 Neisseria meningitidis FAM18 4674995 YP_975007.1 CDS NMC0938 NC_008767.1 938439 938768 R hypothetical protein complement(938439..938768) Neisseria meningitidis FAM18 4675209 YP_975008.1 CDS NMC0940 NC_008767.1 939748 941802 R low G+C; ATP-dependent helicase complement(939748..941802) Neisseria meningitidis FAM18 4675336 YP_975009.1 CDS uvrA NC_008767.1 941817 944663 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(941817..944663) Neisseria meningitidis FAM18 4675335 YP_975010.1 CDS NMC0942 NC_008767.1 944818 945615 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 944818..945615 Neisseria meningitidis FAM18 4676416 YP_975011.1 CDS NMC0944 NC_008767.1 947278 949572 R outer-membrane receptor protein complement(947278..949572) Neisseria meningitidis FAM18 4675339 YP_975012.1 CDS trpG NC_008767.1 949976 950566 D TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 949976..950566 Neisseria meningitidis FAM18 4675340 YP_975013.1 CDS trpD NC_008767.1 950631 951689 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 950631..951689 Neisseria meningitidis FAM18 4674813 YP_975014.1 CDS NMC0949 NC_008767.1 951841 952014 R transposase complement(951841..952014) Neisseria meningitidis FAM18 4675188 YP_975015.1 CDS NMC0950 NC_008767.1 952467 953501 D phage replication initiation protein 952467..953501 Neisseria meningitidis FAM18 4675338 YP_975016.1 CDS NMC0951 NC_008767.1 953492 953836 D hypothetical protein 953492..953836 Neisseria meningitidis FAM18 4676283 YP_975017.1 CDS NMC0952 NC_008767.1 953841 954038 D hypothetical protein 953841..954038 Neisseria meningitidis FAM18 4676099 YP_975018.1 CDS NMC0953 NC_008767.1 954046 954330 D hypothetical protein 954046..954330 Neisseria meningitidis FAM18 4675345 YP_975019.1 CDS NMC0954 NC_008767.1 954337 954615 D hypothetical protein 954337..954615 Neisseria meningitidis FAM18 4675156 YP_975020.1 CDS NMC0955 NC_008767.1 954773 955060 D hypothetical protein 954773..955060 Neisseria meningitidis FAM18 4675148 YP_975021.1 CDS NMC0956 NC_008767.1 955002 955442 D cell-surface protein 955002..955442 Neisseria meningitidis FAM18 4675346 YP_975022.1 CDS NMC0957 NC_008767.1 955953 956513 D hypothetical protein 955953..956513 Neisseria meningitidis FAM18 4675435 YP_975023.1 CDS pntB NC_008767.1 956721 958106 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(956721..958106) Neisseria meningitidis FAM18 4675444 YP_975024.1 CDS NMC0959 NC_008767.1 958172 958555 R hypothetical protein complement(958172..958555) Neisseria meningitidis FAM18 4676095 YP_975025.1 CDS pntA NC_008767.1 958559 960100 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(958559..960100) Neisseria meningitidis FAM18 4675449 YP_975026.1 CDS serB NC_008767.1 960393 961226 D phosphoserine phosphatase 960393..961226 Neisseria meningitidis FAM18 4676094 YP_975027.1 CDS NMC0962 NC_008767.1 961271 962512 D hypothetical protein 961271..962512 Neisseria meningitidis FAM18 4675092 YP_975028.1 CDS purH NC_008767.1 962677 964257 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 962677..964257 Neisseria meningitidis FAM18 4675448 YP_975029.1 CDS NMC0964 NC_008767.1 964856 965812 D transposase 964856..965812 Neisseria meningitidis FAM18 4675787 YP_975030.1 CDS NMC0965 NC_008767.1 965966 966400 D phage related protein 965966..966400 Neisseria meningitidis FAM18 4675447 YP_975031.1 CDS NMC0966 NC_008767.1 966372 966809 D phage related protein 966372..966809 Neisseria meningitidis FAM18 4675457 YP_975032.1 CDS NMC0967 NC_008767.1 967117 967662 D amidase 967117..967662 Neisseria meningitidis FAM18 4675362 YP_975033.1 CDS NMC0969 NC_008767.1 967895 968032 D phage related protein 967895..968032 Neisseria meningitidis FAM18 4675452 YP_975034.1 CDS NMC0970 NC_008767.1 968035 968271 D phage related protein 968035..968271 Neisseria meningitidis FAM18 4675458 YP_975035.1 CDS NMC0971 NC_008767.1 968252 968662 D phage related protein 968252..968662 Neisseria meningitidis FAM18 4675467 YP_975036.1 CDS NMC0972 NC_008767.1 968706 968864 D phage related protein 968706..968864 Neisseria meningitidis FAM18 4675466 YP_975037.1 CDS NMC0973 NC_008767.1 968909 969079 R hypothetical protein complement(968909..969079) Neisseria meningitidis FAM18 4675461 YP_975038.1 CDS NMC0974 NC_008767.1 969092 969310 D phage related protein 969092..969310 Neisseria meningitidis FAM18 4675474 YP_975039.1 CDS NMC0976 NC_008767.1 969503 970468 R transposase for IS1655 complement(969503..970468) Neisseria meningitidis FAM18 4675481 YP_975040.1 CDS NMC0977 NC_008767.1 970767 971774 R transposase for IS1106 complement(970767..971774) Neisseria meningitidis FAM18 4675477 YP_975041.1 CDS NMC0978 NC_008767.1 971907 973676 R surface fibril protein complement(971907..973676) Neisseria meningitidis FAM18 4675482 YP_975042.1 CDS NMC0980 NC_008767.1 975798 976004 R rubredoxin complement(975798..976004) Neisseria meningitidis FAM18 4675480 YP_975043.1 CDS NMC0981 NC_008767.1 976440 977531 R acyl-CoA dehydrogenase complement(976440..977531) Neisseria meningitidis FAM18 4675488 YP_975044.1 CDS NMC0982 NC_008767.1 977666 978349 R hypothetical protein complement(977666..978349) Neisseria meningitidis FAM18 4675487 YP_975045.1 CDS NMC0983 NC_008767.1 978369 978740 R hypothetical protein complement(978369..978740) Neisseria meningitidis FAM18 4675490 YP_975046.1 CDS dld NC_008767.1 979035 980726 R component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase complement(979035..980726) Neisseria meningitidis FAM18 4675495 YP_975047.1 CDS NMC0985 NC_008767.1 981164 985084 D oxidoreductase 981164..985084 Neisseria meningitidis FAM18 4675960 YP_975048.1 CDS NMC0986 NC_008767.1 985137 986162 D hypothetical protein 985137..986162 Neisseria meningitidis FAM18 4675491 YP_975049.1 CDS NMC0988 NC_008767.1 986593 987600 D transposase for IS1106 986593..987600 Neisseria meningitidis FAM18 4675494 YP_975050.1 CDS NMC0992 NC_008767.1 988668 989306 R phage integrase complement(988668..989306) Neisseria meningitidis FAM18 4675513 YP_975051.1 CDS NMC0993 NC_008767.1 989615 990490 R hypothetical protein complement(989615..990490) Neisseria meningitidis FAM18 4675528 YP_975052.1 CDS NMC0995 NC_008767.1 990535 990831 R hypothetical protein complement(990535..990831) Neisseria meningitidis FAM18 4675512 YP_975053.1 CDS NMC0997 NC_008767.1 991130 991507 D phage repressor 991130..991507 Neisseria meningitidis FAM18 4675582 YP_975054.1 CDS NMC0998 NC_008767.1 991536 991781 D hypothetical protein 991536..991781 Neisseria meningitidis FAM18 4676364 YP_975055.1 CDS NMC0999 NC_008767.1 991867 991959 D hypothetical protein 991867..991959 Neisseria meningitidis FAM18 4675510 YP_975056.1 CDS NMC1000 NC_008767.1 992071 992982 D hypothetical protein 992071..992982 Neisseria meningitidis FAM18 4675521 YP_975057.1 CDS NMC1001 NC_008767.1 992979 993461 D hypothetical protein 992979..993461 Neisseria meningitidis FAM18 4675588 YP_975058.1 CDS NMC1002 NC_008767.1 993551 994054 D hypothetical protein 993551..994054 Neisseria meningitidis FAM18 4675585 YP_975059.1 CDS NMC1005 NC_008767.1 994491 994901 D hypothetical protein 994491..994901 Neisseria meningitidis FAM18 4675596 YP_975060.1 CDS NMC1006 NC_008767.1 994906 995655 D transposase 994906..995655 Neisseria meningitidis FAM18 4675589 YP_975061.1 CDS NMC1007 NC_008767.1 996397 997002 R hypothetical protein complement(996397..997002) Neisseria meningitidis FAM18 4675605 YP_975062.1 CDS NMC1008 NC_008767.1 997069 998034 R transposase for IS1655 complement(997069..998034) Neisseria meningitidis FAM18 4675603 YP_975063.1 CDS NMC1009 NC_008767.1 998811 999866 R sulfate-binding protein complement(998811..999866) Neisseria meningitidis FAM18 4675612 YP_975064.1 CDS NMC1010 NC_008767.1 999972 1000454 R hypothetical protein complement(999972..1000454) Neisseria meningitidis FAM18 4675609 YP_975065.1 CDS purK NC_008767.1 1000501 1001637 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(1000501..1001637) Neisseria meningitidis FAM18 4675606 YP_975066.1 CDS NMC1012 NC_008767.1 1001634 1002179 R hypothetical protein complement(1001634..1002179) Neisseria meningitidis FAM18 4675788 YP_975067.1 CDS trpE NC_008767.1 1002176 1003651 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1002176..1003651) Neisseria meningitidis FAM18 4675564 YP_975068.1 CDS NMC1014 NC_008767.1 1003762 1004127 R hypothetical protein complement(1003762..1004127) Neisseria meningitidis FAM18 4674827 YP_975069.1 CDS abcZ NC_008767.1 1004148 1006073 R ABC transporter ATP-binding protein complement(1004148..1006073) Neisseria meningitidis FAM18 4675615 YP_975070.1 CDS dedA NC_008767.1 1006077 1006721 R DedA protein ortholog complement(1006077..1006721) Neisseria meningitidis FAM18 4676301 YP_975071.1 CDS glyA NC_008767.1 1006812 1008062 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(1006812..1008062) Neisseria meningitidis FAM18 4675931 YP_975072.1 CDS ggt NC_008767.1 1008543 1010318 R gamma-glutamyltranspeptidase complement(1008543..1010318) Neisseria meningitidis FAM18 4676575 YP_975073.1 CDS NMC1020 NC_008767.1 1010889 1011116 D hypothetical protein 1010889..1011116 Neisseria meningitidis FAM18 4676621 YP_975074.1 CDS NMC1021 NC_008767.1 1011092 1011310 D hypothetical protein 1011092..1011310 Neisseria meningitidis FAM18 4675623 YP_975075.1 CDS fbp NC_008767.1 1011469 1012443 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(1011469..1012443) Neisseria meningitidis FAM18 4675625 YP_975076.1 CDS NMC1024 NC_008767.1 1012689 1013534 R hypothetical protein complement(1012689..1013534) Neisseria meningitidis FAM18 4675838 YP_975077.1 CDS NMC1026 NC_008767.1 1013622 1014224 R hypothetical protein complement(1013622..1014224) Neisseria meningitidis FAM18 4675621 YP_975078.1 CDS folB NC_008767.1 1014280 1014636 D dihydroneopterin aldolase 1014280..1014636 Neisseria meningitidis FAM18 4675624 YP_975079.1 CDS NMC1028 NC_008767.1 1014670 1015206 D hypothetical protein 1014670..1015206 Neisseria meningitidis FAM18 4676704 YP_975080.1 CDS NMC1029 NC_008767.1 1016250 1016609 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1016250..1016609) Neisseria meningitidis FAM18 4675622 YP_975081.1 CDS NMC1030 NC_008767.1 1016638 1017318 R hypothetical protein complement(1016638..1017318) Neisseria meningitidis FAM18 4675636 YP_975082.1 CDS NMC1031 NC_008767.1 1017483 1020515 D cell-division protein 1017483..1020515 Neisseria meningitidis FAM18 4675568 YP_975083.1 CDS proA NC_008767.1 1020740 1022002 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1020740..1022002) Neisseria meningitidis FAM18 4675630 YP_975084.1 CDS proB NC_008767.1 1022015 1023124 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1022015..1023124) Neisseria meningitidis FAM18 4676055 YP_975085.1 CDS leuA NC_008767.1 1023610 1025163 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1023610..1025163 Neisseria meningitidis FAM18 4675871 YP_975086.1 CDS NMC1035 NC_008767.1 1025363 1026025 D hypothetical protein 1025363..1026025 Neisseria meningitidis FAM18 4676399 YP_975087.1 CDS lgt NC_008767.1 1026108 1026959 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1026108..1026959) Neisseria meningitidis FAM18 4675635 YP_975088.1 CDS NMC1037 NC_008767.1 1027032 1028162 R hypothetical protein complement(1027032..1028162) Neisseria meningitidis FAM18 4676389 YP_975089.1 CDS argB NC_008767.1 1028332 1029228 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1028332..1029228 Neisseria meningitidis FAM18 4675627 YP_975090.1 CDS NMC1039 NC_008767.1 1031085 1031753 R hypothetical protein complement(1031085..1031753) Neisseria meningitidis FAM18 4676425 YP_975091.1 CDS NMC1040 NC_008767.1 1031750 1032481 R chromosome replication initiator DnaA complement(1031750..1032481) Neisseria meningitidis FAM18 4676696 YP_975092.1 CDS NMC1041 NC_008767.1 1032523 1033140 R ABC transporter ATP-binding protein complement(1032523..1033140) Neisseria meningitidis FAM18 4676578 YP_975093.1 CDS NMC1042 NC_008767.1 1033116 1033295 D hypothetical protein 1033116..1033295 Neisseria meningitidis FAM18 4675835 YP_975094.1 CDS NMC1044 NC_008767.1 1033495 1034394 R DNA-binding protein complement(1033495..1034394) Neisseria meningitidis FAM18 4675657 YP_975095.1 CDS NMC1045 NC_008767.1 1034438 1034689 D DNA-binding protein (phage related) 1034438..1034689 Neisseria meningitidis FAM18 4676551 YP_975096.1 CDS NMC1046 NC_008767.1 1034691 1036670 D phage transposase 1034691..1036670 Neisseria meningitidis FAM18 4675736 YP_975097.1 CDS NMC1048 NC_008767.1 1036706 1037620 D phage transposase 1036706..1037620 Neisseria meningitidis FAM18 4675817 YP_975098.1 CDS NMC1049 NC_008767.1 1037686 1037976 D hypothetical protein 1037686..1037976 Neisseria meningitidis FAM18 4675729 YP_975099.1 CDS NMC1050 NC_008767.1 1037963 1038088 D hypothetical protein 1037963..1038088 Neisseria meningitidis FAM18 4675728 YP_975100.1 CDS NMC1051 NC_008767.1 1038085 1038258 D hypothetical protein 1038085..1038258 Neisseria meningitidis FAM18 4675738 YP_975101.1 CDS NMC1052 NC_008767.1 1038251 1038418 D hypothetical protein 1038251..1038418 Neisseria meningitidis FAM18 4675742 YP_975102.1 CDS NMC1053 NC_008767.1 1038482 1038709 D hypothetical protein 1038482..1038709 Neisseria meningitidis FAM18 4675739 YP_975103.1 CDS gam NC_008767.1 1038724 1039242 D host-nuclease inhibitor protein 1038724..1039242 Neisseria meningitidis FAM18 4675752 YP_975104.1 CDS NMC1055 NC_008767.1 1039375 1040340 R transposase for IS1655 complement(1039375..1040340) Neisseria meningitidis FAM18 4676630 YP_975105.1 CDS NMC1057 NC_008767.1 1041177 1041737 D hypothetical protein 1041177..1041737 Neisseria meningitidis FAM18 4675759 YP_975106.1 CDS NMC1058 NC_008767.1 1041748 1043721 D phage tail fiber protein 1041748..1043721 Neisseria meningitidis FAM18 4675770 YP_975107.1 CDS NMC1059 NC_008767.1 1045258 1045863 D hypothetical protein 1045258..1045863 Neisseria meningitidis FAM18 4675765 YP_975108.1 CDS NMC1060 NC_008767.1 1045842 1046138 D hypothetical protein 1045842..1046138 Neisseria meningitidis FAM18 4675786 YP_975109.1 CDS NMC1062 NC_008767.1 1046454 1047597 R ABC transporter ATP-binding protein complement(join(1046454..1047416,1047418..1047597)) Neisseria meningitidis FAM18 4675800 YP_975110.1 CDS NMC1063 NC_008767.1 1048039 1048686 R hypothetical protein complement(1048039..1048686) Neisseria meningitidis FAM18 4675773 YP_975111.1 CDS NMC1065 NC_008767.1 1048683 1049054 R hypothetical protein complement(1048683..1049054) Neisseria meningitidis FAM18 4675796 YP_975112.1 CDS NMC1066 NC_008767.1 1049061 1049732 R hypothetical protein complement(1049061..1049732) Neisseria meningitidis FAM18 4675785 YP_975113.1 CDS NMC1067 NC_008767.1 1049897 1050616 R short chain dehydrogenase complement(1049897..1050616) Neisseria meningitidis FAM18 4675801 YP_975114.1 CDS NMC1068 NC_008767.1 1050699 1052012 R oxidoreductase complement(1050699..1052012) Neisseria meningitidis FAM18 4675805 YP_975115.1 CDS NMC1069 NC_008767.1 1052409 1053281 R poly-isoprenyl transferase complement(1052409..1053281) Neisseria meningitidis FAM18 4675803 YP_975116.1 CDS hscA NC_008767.1 1053296 1055314 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 1053296..1055314 Neisseria meningitidis FAM18 4675802 YP_975117.1 CDS NMC1071 NC_008767.1 1055637 1056200 D hypothetical protein 1055637..1056200 Neisseria meningitidis FAM18 4675806 YP_975118.1 CDS NMC1072 NC_008767.1 1056483 1056998 D hypothetical protein 1056483..1056998 Neisseria meningitidis FAM18 4675810 YP_975119.1 CDS fdx NC_008767.1 1057053 1057394 D ferredoxin 1057053..1057394 Neisseria meningitidis FAM18 4675809 YP_975120.1 CDS NMC1074 NC_008767.1 1057681 1058268 R hypothetical protein complement(1057681..1058268) Neisseria meningitidis FAM18 4675854 YP_975121.1 CDS NMC1076 NC_008767.1 1058481 1058678 D hypothetical protein 1058481..1058678 Neisseria meningitidis FAM18 4675821 YP_975122.1 CDS NMC1077 NC_008767.1 1058746 1059147 R hypothetical protein complement(1058746..1059147) Neisseria meningitidis FAM18 4675811 YP_975123.1 CDS accA NC_008767.1 1059358 1060317 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1059358..1060317 Neisseria meningitidis FAM18 4675827 YP_975124.1 CDS NMC1080 NC_008767.1 1060358 1061695 D hypothetical protein 1060358..1061695 Neisseria meningitidis FAM18 4676302 YP_975125.1 CDS NMC1081 NC_008767.1 1061769 1062554 D RNA methyltransferase 1061769..1062554 Neisseria meningitidis FAM18 4675822 YP_975126.1 CDS NMC1082 NC_008767.1 1062605 1062841 D lipoprotein 1062605..1062841 Neisseria meningitidis FAM18 4676003 YP_975127.1 CDS NMC1083 NC_008767.1 1063023 1063376 D hypothetical protein 1063023..1063376 Neisseria meningitidis FAM18 4675818 YP_975128.1 CDS NMC1084 NC_008767.1 1063388 1063693 D hypothetical protein 1063388..1063693 Neisseria meningitidis FAM18 4676016 YP_975129.1 CDS mpl NC_008767.1 1063755 1065131 D UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso- diaminopimelate ligase 1063755..1065131 Neisseria meningitidis FAM18 4675990 YP_975130.1 CDS bioB NC_008767.1 1065140 1066390 D biotin synthase 1065140..1066390 Neisseria meningitidis FAM18 4676286 YP_975131.1 CDS NMC1088 NC_008767.1 1066374 1067102 R hypothetical protein complement(1066374..1067102) Neisseria meningitidis FAM18 4676627 YP_975132.1 CDS NMC1089 NC_008767.1 1067226 1067465 R hypothetical protein complement(1067226..1067465) Neisseria meningitidis FAM18 4675879 YP_975133.1 CDS ilvD NC_008767.1 1067748 1069607 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(1067748..1069607) Neisseria meningitidis FAM18 4675932 YP_975134.1 CDS cysI NC_008767.1 1069780 1071549 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(1069780..1071549) Neisseria meningitidis FAM18 4676437 YP_975135.1 CDS cysJ NC_008767.1 1071576 1073390 R sulfite reductase subunit alpha complement(1071576..1073390) Neisseria meningitidis FAM18 4675744 YP_975136.1 CDS cysN NC_008767.1 1073387 1074673 R sulfate adenylate transferase subunit 1 complement(1073387..1074673) Neisseria meningitidis FAM18 4675745 YP_975137.1 CDS cysD NC_008767.1 1074712 1075635 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(1074712..1075635) Neisseria meningitidis FAM18 4676022 YP_975138.1 CDS cysH NC_008767.1 1075673 1076407 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(1075673..1076407) Neisseria meningitidis FAM18 4675631 YP_975139.1 CDS cysG NC_008767.1 1076423 1077874 R siroheme synthase complement(1076423..1077874) Neisseria meningitidis FAM18 4675846 YP_975140.1 CDS NMC1097 NC_008767.1 1078324 1078980 R hypothetical protein complement(1078324..1078980) Neisseria meningitidis FAM18 4675845 YP_975141.1 CDS NMC1098 NC_008767.1 1079045 1079935 D hypothetical protein 1079045..1079935 Neisseria meningitidis FAM18 4675163 YP_975142.1 CDS typA NC_008767.1 1080205 1082016 D GTP-binding protein 1080205..1082016 Neisseria meningitidis FAM18 4675927 YP_975143.1 CDS vacB NC_008767.1 1083004 1085379 D ribonuclease 1083004..1085379 Neisseria meningitidis FAM18 4674750 YP_975144.1 CDS guaB NC_008767.1 1085718 1087181 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(1085718..1087181) Neisseria meningitidis FAM18 4676712 YP_975145.1 CDS glnD NC_008767.1 1087328 1089886 R [protein-PII] uridylyltransferase complement(1087328..1089886) Neisseria meningitidis FAM18 4676490 YP_975146.1 CDS NMC1106 NC_008767.1 1089935 1090255 R transcriptional regulator complement(1089935..1090255) Neisseria meningitidis FAM18 4676609 YP_975147.1 CDS bfrB NC_008767.1 1090579 1091052 R bacterioferritin B complement(1090579..1091052) Neisseria meningitidis FAM18 4675912 YP_975148.1 CDS bfrA NC_008767.1 1091080 1091544 R bacterioferritin A complement(1091080..1091544) Neisseria meningitidis FAM18 4676570 YP_975149.1 CDS lipA NC_008767.1 1092007 1093077 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1092007..1093077) Neisseria meningitidis FAM18 4676569 YP_975150.1 CDS lipB NC_008767.1 1092983 1093555 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1092983..1093555) Neisseria meningitidis FAM18 4676395 YP_975151.1 CDS NMC1112 NC_008767.1 1093608 1093883 R hypothetical protein complement(1093608..1093883) Neisseria meningitidis FAM18 4676379 YP_975152.1 CDS NMC1113 NC_008767.1 1094068 1095138 D hypothetical protein 1094068..1095138 Neisseria meningitidis FAM18 4675905 YP_975153.1 CDS NMC1114 NC_008767.1 1095385 1096332 R hypothetical protein complement(1095385..1096332) Neisseria meningitidis FAM18 4675859 YP_975154.1 CDS NMC1115 NC_008767.1 1096347 1096766 R hypothetical protein complement(1096347..1096766) Neisseria meningitidis FAM18 4675901 YP_975155.1 CDS NMC1116 NC_008767.1 1096835 1097494 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1096835..1097494 Neisseria meningitidis FAM18 4675883 YP_975156.1 CDS NMC1117 NC_008767.1 1097553 1098086 D hypothetical protein 1097553..1098086 Neisseria meningitidis FAM18 4676703 YP_975157.1 CDS NMC1118 NC_008767.1 1098201 1098650 R multiple antibiotic resistance; transcriptional regulator complement(1098201..1098650) Neisseria meningitidis FAM18 4675160 YP_975158.1 CDS NMC1120 NC_008767.1 1099113 1100069 R transposase complement(1099113..1100069) Neisseria meningitidis FAM18 4676176 YP_975159.1 CDS NMC1121 NC_008767.1 1100551 1100643 D hypothetical protein 1100551..1100643 Neisseria meningitidis FAM18 4676628 YP_975160.1 CDS NMC1122 NC_008767.1 1100666 1100815 D hypothetical protein 1100666..1100815 Neisseria meningitidis FAM18 4676593 YP_975161.1 CDS NMC1123 NC_008767.1 1100906 1101061 D transposase (fragment) 1100906..1101061 Neisseria meningitidis FAM18 4676688 YP_975162.1 CDS NMC1124 NC_008767.1 1101279 1101602 R hypothetical protein complement(1101279..1101602) Neisseria meningitidis FAM18 4676565 YP_975163.1 CDS NMC1125 NC_008767.1 1101647 1102162 R hypothetical protein complement(1101647..1102162) Neisseria meningitidis FAM18 4676573 YP_975164.1 CDS NMC1126 NC_008767.1 1102628 1104550 R coiled coils, 90-110, 568-587, 596-626; ABC transporter ATP-binding protein complement(1102628..1104550) Neisseria meningitidis FAM18 4676550 YP_975165.1 CDS NMC1127 NC_008767.1 1104627 1105058 R hypothetical protein complement(1104627..1105058) Neisseria meningitidis FAM18 4676568 YP_975166.2 CDS hom NC_008767.1 1105196 1106503 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1105196..1106503 Neisseria meningitidis FAM18 4676547 YP_975167.1 CDS NMC1129 NC_008767.1 1106496 1106930 D hypothetical protein 1106496..1106930 Neisseria meningitidis FAM18 4676422 YP_975168.1 CDS hupB NC_008767.1 1106989 1107258 R DNA-binding protein complement(1106989..1107258) Neisseria meningitidis FAM18 4675855 YP_975169.1 CDS lon NC_008767.1 1107440 1109890 R ATP-dependent protease complement(1107440..1109890) Neisseria meningitidis FAM18 4676455 YP_975170.1 CDS NMC1132 NC_008767.1 1110249 1111244 D hypothetical protein 1110249..1111244 Neisseria meningitidis FAM18 4676391 YP_975171.1 CDS recD NC_008767.1 1111272 1113017 R exodeoxyribonuclease V subunit alpha complement(1111272..1113017) Neisseria meningitidis FAM18 4676506 YP_975172.1 CDS NMC1134 NC_008767.1 1113085 1113771 R ABC transporter ATP-binding protein complement(1113085..1113771) Neisseria meningitidis FAM18 4675757 YP_975173.1 CDS NMC1135 NC_008767.1 1113773 1115020 R hypothetical protein complement(1113773..1115020) Neisseria meningitidis FAM18 4676272 YP_975174.1 CDS NMC1136 NC_008767.1 1115213 1115503 D hypothetical protein 1115213..1115503 Neisseria meningitidis FAM18 4676496 YP_975175.1 CDS recR NC_008767.1 1115559 1116179 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(1115559..1116179) Neisseria meningitidis FAM18 4676458 YP_975176.1 CDS NMC1138 NC_008767.1 1116243 1117781 R peptidyl-prolyl cis-trans isomerase complement(1116243..1117781) Neisseria meningitidis FAM18 4675671 YP_975177.1 CDS NMC1139 NC_008767.1 1117836 1118210 R hypothetical protein complement(1117836..1118210) Neisseria meningitidis FAM18 4676462 YP_975178.1 CDS NMC1140 NC_008767.1 1118360 1119988 D ABC transporter ATP-binding protein 1118360..1119988 Neisseria meningitidis FAM18 4676459 YP_975179.1 CDS cca NC_008767.1 1120060 1121313 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 1120060..1121313 Neisseria meningitidis FAM18 4676393 YP_975180.1 CDS NMC1143 NC_008767.1 1121536 1121844 D hypothetical protein 1121536..1121844 Neisseria meningitidis FAM18 4676542 YP_975181.1 CDS ruvB NC_008767.1 1121926 1122957 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1121926..1122957 Neisseria meningitidis FAM18 4676412 YP_975182.1 CDS rpe NC_008767.1 1122980 1123708 R ribulose-phosphate 3-epimerase complement(1122980..1123708) Neisseria meningitidis FAM18 4675530 YP_975183.1 CDS NMC1146 NC_008767.1 1123854 1124288 D hypothetical protein 1123854..1124288 Neisseria meningitidis FAM18 4675411 YP_975184.1 CDS NMC1147 NC_008767.1 1124301 1125164 R hypothetical protein complement(join(1124301..1124507,1124511..1125164)) Neisseria meningitidis FAM18 4676373 YP_975185.2 CDS ribC NC_008767.1 1125172 1125789 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1125172..1125789) Neisseria meningitidis FAM18 4676365 YP_975186.1 CDS NMC1149 NC_008767.1 1125952 1126530 R molybdopterin-guanine dinucleotide biosynthesis protein A complement(1125952..1126530) Neisseria meningitidis FAM18 4675598 YP_975187.1 CDS NMC1150 NC_008767.1 1126772 1128544 D two-component system sensor kinase 1126772..1128544 Neisseria meningitidis FAM18 4676169 YP_975188.1 CDS NMC1151 NC_008767.1 1128541 1129197 D two-component system response regulator 1128541..1129197 Neisseria meningitidis FAM18 4676317 YP_975189.1 CDS purM NC_008767.1 1129671 1130705 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(1129671..1130705) Neisseria meningitidis FAM18 4676292 YP_975190.1 CDS NMC1154 NC_008767.1 1131464 1132141 D hypothetical protein 1131464..1132141 Neisseria meningitidis FAM18 4675795 YP_975191.1 CDS ribA NC_008767.1 1132134 1132727 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1132134..1132727 Neisseria meningitidis FAM18 4676360 YP_975192.1 CDS NMC1156 NC_008767.1 1132895 1133909 D hypothetical protein join(1132895..1133209,1133208..1133909) Neisseria meningitidis FAM18 4675602 YP_975193.2 CDS ribB NC_008767.1 1134377 1135468 D bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein 1134377..1135468 Neisseria meningitidis FAM18 4676188 YP_975194.1 CDS NMC1158 NC_008767.1 1135776 1136102 R type I restriction enzyme system modification protein complement(1135776..1136102) Neisseria meningitidis FAM18 4675597 YP_975195.1 CDS NMC1159 NC_008767.1 1136390 1137700 R recombination factor protein RarA complement(1136390..1137700) Neisseria meningitidis FAM18 4676330 YP_975196.1 CDS NMC1160 NC_008767.1 1137949 1138434 D hypothetical protein 1137949..1138434 Neisseria meningitidis FAM18 4676243 YP_975197.1 CDS NMC1162 NC_008767.1 1139484 1140437 R LysR family transcriptional regulator complement(1139484..1140437) Neisseria meningitidis FAM18 4676247 YP_975198.1 CDS NMC1163 NC_008767.1 1140612 1142123 D hypothetical protein 1140612..1142123 Neisseria meningitidis FAM18 4676203 YP_975199.1 CDS NMC1164 NC_008767.1 1142375 1142746 D lipoprotein 1142375..1142746 Neisseria meningitidis FAM18 4676196 YP_975200.1 CDS thrC NC_008767.1 1142819 1144228 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1142819..1144228 Neisseria meningitidis FAM18 4676213 YP_975201.1 CDS NMC1166 NC_008767.1 1144274 1145068 D hypothetical protein 1144274..1145068 Neisseria meningitidis FAM18 4675198 YP_975202.1 CDS fpr NC_008767.1 1145256 1146032 D ferredoxin-NADP reductase 1145256..1146032 Neisseria meningitidis FAM18 4676193 YP_975203.1 CDS NMC1170 NC_008767.1 1146700 1149210 R P-type cation-transporting ATPase complement(1146700..1149210) Neisseria meningitidis FAM18 4676684 YP_975204.1 CDS NMC1171 NC_008767.1 1149168 1150346 R hypothetical protein complement(1149168..1150346) Neisseria meningitidis FAM18 4676190 YP_975205.1 CDS NMC1172 NC_008767.1 1150351 1151655 R hypothetical protein complement(1150351..1151655) Neisseria meningitidis FAM18 4676234 YP_975206.1 CDS NMC1173 NC_008767.1 1151784 1152509 R hypothetical protein complement(1151784..1152509) Neisseria meningitidis FAM18 4676181 YP_975207.1 CDS radC NC_008767.1 1152582 1153259 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(1152582..1153259) Neisseria meningitidis FAM18 4676164 YP_975208.1 CDS gshA NC_008767.1 1153382 1154731 R glutamate--cysteine ligase complement(1153382..1154731) Neisseria meningitidis FAM18 4675734 YP_975209.1 CDS leuC NC_008767.1 1154991 1156400 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1154991..1156400 Neisseria meningitidis FAM18 4676529 YP_975210.1 CDS NMC1178 NC_008767.1 1156446 1156751 D lipoprotein 1156446..1156751 Neisseria meningitidis FAM18 4676388 YP_975211.1 CDS leuD NC_008767.1 1156813 1157454 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1156813..1157454 Neisseria meningitidis FAM18 4676137 YP_975212.1 CDS NMC1180 NC_008767.1 1157624 1158893 D deleted EC_number 2.1.1.73; DNA modification methylase join(1157624..1158025,1158025..1158420,1158420..1158893) Neisseria meningitidis FAM18 4676229 YP_975213.1 CDS NMC1181 NC_008767.1 1158909 1159640 D type II restriction endonuclease join(1158909..1159067,1159071..1159640) Neisseria meningitidis FAM18 4676141 YP_975214.1 CDS leuB NC_008767.1 1159674 1160744 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1159674..1160744 Neisseria meningitidis FAM18 4676144 YP_975215.1 CDS NMC1183 NC_008767.1 1160907 1161470 D hypothetical protein 1160907..1161470 Neisseria meningitidis FAM18 4676387 YP_975216.1 CDS aspA NC_008767.1 1161930 1163327 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1161930..1163327 Neisseria meningitidis FAM18 4676138 YP_975217.1 CDS NMC1186 NC_008767.1 1163399 1164274 R hypothetical protein complement(1163399..1164274) Neisseria meningitidis FAM18 4675620 YP_975218.1 CDS NMC1188 NC_008767.1 1164276 1164998 R molecuar chaperone DnaJ complement(1164276..1164998) Neisseria meningitidis FAM18 4676100 YP_975219.1 CDS NMC1189 NC_008767.1 1165020 1165499 R hypothetical protein complement(1165020..1165499) Neisseria meningitidis FAM18 4676133 YP_975220.1 CDS NMC1190 NC_008767.1 1165560 1165937 D hypothetical protein 1165560..1165937 Neisseria meningitidis FAM18 4675977 YP_975221.1 CDS NMC1191 NC_008767.1 1165969 1166835 D hypothetical protein 1165969..1166835 Neisseria meningitidis FAM18 4676051 YP_975222.1 CDS NMC1192 NC_008767.1 1166933 1167892 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1166933..1167892 Neisseria meningitidis FAM18 4676039 YP_975223.1 CDS NMC1193 NC_008767.1 1167986 1170925 R type III restriction-modification system endonuclease protein complement(1167986..1170925) Neisseria meningitidis FAM18 4676035 YP_975224.1 CDS NMC1194 NC_008767.1 1170938 1172912 R hypothetical protein complement(join(1170938..1172824,1172823..1172912)) Neisseria meningitidis FAM18 4675680 YP_975225.1 CDS ppiA NC_008767.1 1173028 1173585 R peptidyl-prolyl cis-trans isomerase A complement(1173028..1173585) Neisseria meningitidis FAM18 4675699 YP_975226.1 CDS NMC1196 NC_008767.1 1173650 1174576 R hypothetical protein complement(1173650..1174576) Neisseria meningitidis FAM18 4676074 YP_975227.1 CDS NMC1197 NC_008767.1 1174564 1175157 R cation uptake regulator complement(1174564..1175157) Neisseria meningitidis FAM18 4675675 YP_975228.1 CDS NMC1198 NC_008767.1 1175111 1175668 R protein-tyrosine-phosphatase complement(1175111..1175668) Neisseria meningitidis FAM18 4675690 YP_975229.1 CDS NMC1199 NC_008767.1 1175691 1176806 R hypothetical protein complement(1175691..1176806) Neisseria meningitidis FAM18 4675661 YP_975230.1 CDS NMC1200 NC_008767.1 1176920 1178017 R hypothetical protein complement(1176920..1178017) Neisseria meningitidis FAM18 4675660 YP_975231.1 CDS NMC1201 NC_008767.1 1178099 1179730 R hypothetical protein complement(1178099..1179730) Neisseria meningitidis FAM18 4675563 YP_975232.1 CDS NMC1202 NC_008767.1 1179830 1180042 R mercuric ion binding protein complement(1179830..1180042) Neisseria meningitidis FAM18 4675558 YP_975233.1 CDS NMC1203 NC_008767.1 1180672 1182108 D polysaccharide modification protein 1180672..1182108 Neisseria meningitidis FAM18 4675555 YP_975234.1 CDS NMC1204 NC_008767.1 1182119 1183105 D hypothetical protein 1182119..1183105 Neisseria meningitidis FAM18 4675554 YP_975235.1 CDS NMC1205 NC_008767.1 1183102 1184295 D hypothetical protein 1183102..1184295 Neisseria meningitidis FAM18 4675549 YP_975236.1 CDS NMC1207 NC_008767.1 1184505 1186097 D activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1184505..1186097 Neisseria meningitidis FAM18 4675425 YP_975237.1 CDS NMC1208 NC_008767.1 1186187 1188214 R transmembrane transport protein complement(1186187..1188214) Neisseria meningitidis FAM18 4675423 YP_975238.1 CDS gcr NC_008767.1 1188503 1190509 D site-specific recombinase 1188503..1190509 Neisseria meningitidis FAM18 4675415 YP_975239.1 CDS mltB NC_008767.1 1190632 1191723 R murein hydrolase complement(1190632..1191723) Neisseria meningitidis FAM18 4676597 YP_975240.1 CDS NMC1213 NC_008767.1 1191872 1193425 R oxidoreductase complement(1191872..1193425) Neisseria meningitidis FAM18 4676289 YP_975241.1 CDS mfd NC_008767.1 1193484 1197611 D transcription-repair coupling factor 1193484..1197611 Neisseria meningitidis FAM18 4675414 YP_975242.1 CDS panD NC_008767.1 1197760 1198143 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 1197760..1198143 Neisseria meningitidis FAM18 4676274 YP_975243.1 CDS kdsA NC_008767.1 1198165 1199007 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1198165..1199007 Neisseria meningitidis FAM18 4676179 YP_975244.1 CDS NMC1219 NC_008767.1 1199022 1199462 D hypothetical protein 1199022..1199462 Neisseria meningitidis FAM18 4675904 YP_975245.1 CDS eno NC_008767.1 1199509 1200795 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1199509..1200795 Neisseria meningitidis FAM18 4675401 YP_975246.1 CDS NMC1221 NC_008767.1 1200809 1201087 D hypothetical protein 1200809..1201087 Neisseria meningitidis FAM18 4675900 YP_975247.1 CDS NMC1222 NC_008767.1 1201128 1201418 R iron-sulfur binding protein complement(1201128..1201418) Neisseria meningitidis FAM18 4675396 YP_975248.1 CDS nrdB NC_008767.1 1201643 1202776 R B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta complement(1201643..1202776) Neisseria meningitidis FAM18 4675395 YP_975249.1 CDS NMC1225 NC_008767.1 1202990 1203913 R hypothetical protein complement(1202990..1203913) Neisseria meningitidis FAM18 4676220 YP_975250.1 CDS nrdA NC_008767.1 1203936 1206215 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1203936..1206215) Neisseria meningitidis FAM18 4675391 YP_975251.1 CDS NMC1229 NC_008767.1 1206744 1207055 D secreted protein; hypothetical protein 1206744..1207055 Neisseria meningitidis FAM18 4676125 YP_975252.1 CDS NMC1231 NC_008767.1 1207366 1208133 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1207366..1208133) Neisseria meningitidis FAM18 4675390 YP_975253.1 CDS fpg NC_008767.1 1208221 1209063 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(1208221..1209063) Neisseria meningitidis FAM18 4675389 YP_975254.1 CDS NMC1233 NC_008767.1 1209100 1209765 R hypothetical protein complement(1209100..1209765) Neisseria meningitidis FAM18 4676687 YP_975255.1 CDS NMC1234 NC_008767.1 1209944 1211920 D membrane bound murein transglycosylase 1209944..1211920 Neisseria meningitidis FAM18 4675386 YP_975256.1 CDS NMC1235 NC_008767.1 1211988 1212680 D ribosomal small subunit pseudouridine synthase 1211988..1212680 Neisseria meningitidis FAM18 4675378 YP_975257.1 CDS cmk NC_008767.1 1214782 1215438 D cytidylate kinase 1214782..1215438 Neisseria meningitidis FAM18 4675374 YP_975258.1 CDS rpsA NC_008767.1 1215567 1217279 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1215567..1217279 Neisseria meningitidis FAM18 4676672 YP_975259.1 CDS ihfB NC_008767.1 1217290 1217604 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1217290..1217604 Neisseria meningitidis FAM18 4675266 YP_975260.1 CDS NMC1240 NC_008767.1 1217954 1218361 R transcriptional regulator complement(1217954..1218361) Neisseria meningitidis FAM18 4676468 YP_975261.1 CDS adhC NC_008767.1 1218482 1219618 D deleted EC_number 1.2.1.1; alcohol dehydrogenase 1218482..1219618 Neisseria meningitidis FAM18 4675371 YP_975262.1 CDS esd NC_008767.1 1219627 1220454 D esterase 1219627..1220454 Neisseria meningitidis FAM18 4675504 YP_975263.1 CDS NMC1243 NC_008767.1 1220845 1221996 D nucleotide-binding protein 1220845..1221996 Neisseria meningitidis FAM18 4675889 YP_975264.1 CDS ndk NC_008767.1 1222055 1222480 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1222055..1222480 Neisseria meningitidis FAM18 4675364 YP_975265.1 CDS NMC1245 NC_008767.1 1222623 1223717 D hypothetical protein 1222623..1223717 Neisseria meningitidis FAM18 4676238 YP_975266.1 CDS NMC1246 NC_008767.1 1223684 1224481 D lipoprotein 1223684..1224481 Neisseria meningitidis FAM18 4675363 YP_975267.1 CDS ispG NC_008767.1 1224497 1225762 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1224497..1225762 Neisseria meningitidis FAM18 4675361 YP_975268.1 CDS clpP NC_008767.1 1225819 1226433 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1225819..1226433) Neisseria meningitidis FAM18 4675290 YP_975269.1 CDS tig NC_008767.1 1226529 1227842 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(1226529..1227842) Neisseria meningitidis FAM18 4676503 YP_975270.1 CDS NMC1251 NC_008767.1 1228048 1230486 R DNA translocase FtsK complement(1228048..1230486) Neisseria meningitidis FAM18 4675193 YP_975271.1 CDS uraA NC_008767.1 1230685 1231920 D uracil permease 1230685..1231920 Neisseria meningitidis FAM18 4675286 YP_975272.1 CDS NMC1253 NC_008767.1 1231972 1232454 R hypothetical protein complement(1231972..1232454) Neisseria meningitidis FAM18 4676671 YP_975273.1 CDS NMC1254 NC_008767.1 1232560 1232963 D hypothetical protein join(1232560..1232751,1232751..1232963) Neisseria meningitidis FAM18 4675284 YP_975274.1 CDS pss NC_008767.1 1233037 1233783 D phosphatidylserine synthase 1233037..1233783 Neisseria meningitidis FAM18 4675280 YP_975275.1 CDS NMC1256 NC_008767.1 1233784 1234590 D hypothetical protein 1233784..1234590 Neisseria meningitidis FAM18 4675984 YP_975276.1 CDS rplI NC_008767.1 1235378 1235830 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(1235378..1235830) Neisseria meningitidis FAM18 4675824 YP_975277.1 CDS rpsR NC_008767.1 1235847 1236077 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1235847..1236077) Neisseria meningitidis FAM18 4675463 YP_975278.1 CDS priB NC_008767.1 1236084 1236386 R primosomal replication protein complement(1236084..1236386) Neisseria meningitidis FAM18 4675219 YP_975279.1 CDS rpsF NC_008767.1 1236387 1236755 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1236387..1236755) Neisseria meningitidis FAM18 4676068 YP_975280.1 CDS trxB NC_008767.1 1236910 1237860 R thioredoxin reductase complement(1236910..1237860) Neisseria meningitidis FAM18 4675304 YP_975281.1 CDS NMC1262 NC_008767.1 1237849 1240161 D cation-transporting ATPase 1237849..1240161 Neisseria meningitidis FAM18 4675184 YP_975282.1 CDS uvrC NC_008767.1 1240216 1242102 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1240216..1242102 Neisseria meningitidis FAM18 4675132 YP_975283.1 CDS NMC1265 NC_008767.1 1242189 1243623 D hypothetical protein join(1242189..1242491,1242490..1243623) Neisseria meningitidis FAM18 4676601 YP_975284.1 CDS trmB NC_008767.1 1243745 1244461 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1243745..1244461 Neisseria meningitidis FAM18 4675127 YP_975285.1 CDS NMC1268 NC_008767.1 1244642 1244929 R hypothetical protein complement(1244642..1244929) Neisseria meningitidis FAM18 4675115 YP_975286.1 CDS uvrB NC_008767.1 1245041 1247068 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1245041..1247068) Neisseria meningitidis FAM18 4675489 YP_975287.1 CDS NMC1270 NC_008767.1 1247397 1248881 R carboxy-terminal processing protease complement(1247397..1248881) Neisseria meningitidis FAM18 4676417 YP_975288.1 CDS NMC1271 NC_008767.1 1249008 1250813 R hypothetical protein complement(1249008..1250813) Neisseria meningitidis FAM18 4675080 YP_975289.1 CDS NMC1273 NC_008767.1 1251141 1251701 D lipoprotein 1251141..1251701 Neisseria meningitidis FAM18 4675078 YP_975290.1 CDS NMC1274 NC_008767.1 1251703 1252251 D hypothetical protein 1251703..1252251 Neisseria meningitidis FAM18 4675076 YP_975291.1 CDS NMC1275 NC_008767.1 1252244 1252699 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1252244..1252699 Neisseria meningitidis FAM18 4675023 YP_975292.1 CDS NMC1276 NC_008767.1 1252709 1253365 R hydrolase complement(1252709..1253365) Neisseria meningitidis FAM18 4674938 YP_975293.1 CDS proS NC_008767.1 1253428 1255140 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(1253428..1255140) Neisseria meningitidis FAM18 4674927 YP_975294.1 CDS aceE NC_008767.1 1255834 1258497 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1255834..1258497 Neisseria meningitidis FAM18 4676052 YP_975295.1 CDS aceF NC_008767.1 1258647 1260248 D dihydrolipoamide acetyltransferase 1258647..1260248 Neisseria meningitidis FAM18 4675427 YP_975296.1 CDS lpdA NC_008767.1 1260325 1262112 D dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) 1260325..1262112 Neisseria meningitidis FAM18 4676165 YP_975297.1 CDS NMC1281 NC_008767.1 1262472 1264010 R hypothetical protein complement(1262472..1264010) Neisseria meningitidis FAM18 4676356 YP_975298.1 CDS NMC1282 NC_008767.1 1264146 1266269 R TonB-dependent receptor protein complement(1264146..1266269) Neisseria meningitidis FAM18 4674899 YP_975299.1 CDS NMC1283 NC_008767.1 1266539 1267324 R inositol monophosphatase complement(1266539..1267324) Neisseria meningitidis FAM18 4674867 YP_975300.1 CDS NMC1284 NC_008767.1 1267505 1268383 D SpoU methylase family protein 1267505..1268383 Neisseria meningitidis FAM18 4674847 YP_975301.1 CDS NMC1285 NC_008767.1 1268423 1269301 D hypothetical protein 1268423..1269301 Neisseria meningitidis FAM18 4674843 YP_975302.1 CDS NMC1286 NC_008767.1 1269337 1270593 D SUN-family protein 1269337..1270593 Neisseria meningitidis FAM18 4674839 YP_975303.1 CDS NMC1287 NC_008767.1 1271689 1272123 D coiled coil, 93-110; hypothetical protein 1271689..1272123 Neisseria meningitidis FAM18 4674834 YP_975304.1 CDS NMC1288 NC_008767.1 1272172 1273515 R aldehyde dehydrogenase complement(1272172..1273515) Neisseria meningitidis FAM18 4674829 YP_975305.1 CDS NMC1289 NC_008767.1 1273520 1274233 R hypothetical protein complement(1273520..1274233) Neisseria meningitidis FAM18 4674792 YP_975306.1 CDS gatC NC_008767.1 1274315 1274614 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1274315..1274614 Neisseria meningitidis FAM18 4674787 YP_975307.1 CDS gatA NC_008767.1 1274677 1276122 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1274677..1276122 Neisseria meningitidis FAM18 4676620 YP_975308.1 CDS NMC1292 NC_008767.1 1276119 1277051 D hypothetical protein 1276119..1277051 Neisseria meningitidis FAM18 4676638 YP_975309.1 CDS gatB NC_008767.1 1277094 1278524 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1277094..1278524 Neisseria meningitidis FAM18 4674786 YP_975310.1 CDS NMC1294 NC_008767.1 1278616 1279626 D iron/sulfur-binding oxidoreductase 1278616..1279626 Neisseria meningitidis FAM18 4676619 YP_975311.1 CDS pdxH NC_008767.1 1279755 1280387 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1279755..1280387) Neisseria meningitidis FAM18 4674772 YP_975312.1 CDS NMC1296 NC_008767.1 1281044 1281814 D pseudouridine synthase 1281044..1281814 Neisseria meningitidis FAM18 4676156 YP_975313.1 CDS NMC1297 NC_008767.1 1281883 1283424 R integral membrane transporter complement(1281883..1283424) Neisseria meningitidis FAM18 4674766 YP_975314.1 CDS xseA NC_008767.1 1284671 1286026 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1284671..1286026) Neisseria meningitidis FAM18 4674752 YP_975315.1 CDS nadE NC_008767.1 1286223 1287044 D NH(3)-dependent NAD synthetase 1286223..1287044 Neisseria meningitidis FAM18 4676682 YP_975316.1 CDS NMC1300 NC_008767.1 1287112 1287585 R hypothetical protein complement(1287112..1287585) Neisseria meningitidis FAM18 4676253 YP_975317.1 CDS trxA NC_008767.1 1287883 1288215 D thioredoxin 1287883..1288215 Neisseria meningitidis FAM18 4674748 YP_975318.1 CDS NMC1302 NC_008767.1 1288268 1289185 R hypothetical protein complement(1288268..1289185) Neisseria meningitidis FAM18 4675183 YP_975319.1 CDS NMC1303 NC_008767.1 1289543 1290931 D ATP-dependent RNA helicase 1289543..1290931 Neisseria meningitidis FAM18 4676600 YP_975320.1 CDS NMC1304 NC_008767.1 1291573 1292127 R membrane lipoprotein complement(1291573..1292127) Neisseria meningitidis FAM18 4676370 YP_975321.1 CDS NMC1305 NC_008767.1 1292212 1292772 R hypothetical protein complement(1292212..1292772) Neisseria meningitidis FAM18 4676556 YP_975322.1 CDS argD NC_008767.1 1293116 1294312 D DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 1293116..1294312 Neisseria meningitidis FAM18 4676714 YP_975323.1 CDS clpX NC_008767.1 1294415 1295659 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1294415..1295659) Neisseria meningitidis FAM18 4676443 YP_975324.1 CDS rbfA NC_008767.1 1295850 1296221 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1295850..1296221 Neisseria meningitidis FAM18 4676504 YP_975325.1 CDS truB NC_008767.1 1296227 1297186 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1296227..1297186 Neisseria meningitidis FAM18 4675735 YP_975326.1 CDS NMC1310 NC_008767.1 1297477 1299711 D type III restriction/modification system modification methylase 1297477..1299711 Neisseria meningitidis FAM18 4675186 YP_975327.1 CDS NMC1311 NC_008767.1 1299659 1302475 D type III restriction/modification system enzyme 1299659..1302475 Neisseria meningitidis FAM18 4674747 YP_975328.1 CDS lldA NC_008767.1 1302624 1303796 R L-lactate dehydrogenase complement(1302624..1303796) Neisseria meningitidis FAM18 4675176 YP_975329.1 CDS NMC1314 NC_008767.1 1304085 1304531 D DNA-binding protein 1304085..1304531 Neisseria meningitidis FAM18 4676382 YP_975330.1 CDS NMC1315 NC_008767.1 1304560 1305774 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 1304560..1305774 Neisseria meningitidis FAM18 4676709 YP_975331.1 CDS NMC1317 NC_008767.1 1306035 1306421 D scaffold protein 1306035..1306421 Neisseria meningitidis FAM18 4675142 YP_975332.1 CDS NMC1318 NC_008767.1 1306508 1306828 D HesB-like protein 1306508..1306828 Neisseria meningitidis FAM18 4675141 YP_975333.1 CDS hscB NC_008767.1 1307091 1307591 D chaperone protein 1307091..1307591 Neisseria meningitidis FAM18 4676689 YP_975334.1 CDS gyrA NC_008767.1 1307689 1310439 D DNA gyrase subunit A 1307689..1310439 Neisseria meningitidis FAM18 4676464 YP_975335.1 CDS NMC1323 NC_008767.1 1311521 1311712 D transposase (fragment) 1311521..1311712 Neisseria meningitidis FAM18 4676275 YP_975336.1 CDS NMC1325 NC_008767.1 1312043 1312594 R hypothetical protein complement(1312043..1312594) Neisseria meningitidis FAM18 4675166 YP_975337.1 CDS pgi NC_008767.1 1312608 1314254 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1312608..1314254) Neisseria meningitidis FAM18 4675180 YP_975338.1 CDS NMC1328 NC_008767.1 1314375 1315259 R transcriptional regulator complement(1314375..1315259) Neisseria meningitidis FAM18 4676151 YP_975339.1 CDS glk NC_008767.1 1315273 1316259 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(1315273..1316259) Neisseria meningitidis FAM18 4675161 YP_975340.1 CDS pgl NC_008767.1 1316240 1316935 R 6-phosphogluconolactonase complement(1316240..1316935) Neisseria meningitidis FAM18 4676606 YP_975341.1 CDS zwf NC_008767.1 1317215 1318660 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1317215..1318660) Neisseria meningitidis FAM18 4676139 YP_975342.1 CDS edd NC_008767.1 1319176 1321011 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1319176..1321011 Neisseria meningitidis FAM18 4676400 YP_975343.1 CDS eda NC_008767.1 1321129 1321830 D catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1321129..1321830 Neisseria meningitidis FAM18 4675911 YP_975344.1 CDS mutY NC_008767.1 1323283 1324332 D adenine glycosylase 1323283..1324332 Neisseria meningitidis FAM18 4674743 YP_975345.1 CDS sodC NC_008767.1 1324749 1325309 D superoxide dismutase 1324749..1325309 Neisseria meningitidis FAM18 4675709 YP_975346.1 CDS NMC1340 NC_008767.1 1325895 1326395 R insertion element IS1106 transposase (fragment) complement(1325895..1326395) Neisseria meningitidis FAM18 4675025 YP_975347.1 CDS NMC1341 NC_008767.1 1326522 1326839 R remnant of insertion element IS1106A3 transposase complement(1326522..1326839) Neisseria meningitidis FAM18 4674822 YP_975348.1 CDS NMC1342 NC_008767.1 1327063 1329291 R cytolysin secretion ABC transporter complement(1327063..1329291) Neisseria meningitidis FAM18 4674838 YP_975349.1 CDS NMC1343 NC_008767.1 1329996 1330649 R insertion element IS1016 transposase complement(1329996..1330649) Neisseria meningitidis FAM18 4676235 YP_975350.1 CDS NMC1344 NC_008767.1 1331255 1332070 D RTX iron-regulated frpc protein outer membrane 1331255..1332070 Neisseria meningitidis FAM18 4676236 YP_975351.1 CDS pepN NC_008767.1 1338602 1341205 R aminopeptidase complement(1338602..1341205) Neisseria meningitidis FAM18 4675356 YP_975352.1 CDS NMC1348 NC_008767.1 1341417 1342211 R hypothetical protein complement(1341417..1342211) Neisseria meningitidis FAM18 4675893 YP_975353.1 CDS NMC1351 NC_008767.1 1342961 1343830 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1342961..1343830) Neisseria meningitidis FAM18 4675297 YP_975354.1 CDS ruvC NC_008767.1 1343881 1344423 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1343881..1344423) Neisseria meningitidis FAM18 4675298 YP_975355.1 CDS fis NC_008767.1 1344420 1344659 R Fis family transcriptional regulator complement(1344420..1344659) Neisseria meningitidis FAM18 4675120 YP_975356.1 CDS NMC1354 NC_008767.1 1344689 1345699 R hypothetical protein complement(1344689..1345699) Neisseria meningitidis FAM18 4676678 YP_975357.1 CDS NMC1355 NC_008767.1 1345987 1347438 D ATP-dependent RNA helicase 1345987..1347438 Neisseria meningitidis FAM18 4675946 YP_975358.1 CDS NMC1357 NC_008767.1 1348134 1349261 D hypothetical protein 1348134..1349261 Neisseria meningitidis FAM18 4675947 YP_975359.1 CDS NMC1358 NC_008767.1 1349291 1350169 D hypothetical protein 1349291..1350169 Neisseria meningitidis FAM18 4675139 YP_975360.1 CDS lysS NC_008767.1 1350587 1352098 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(1350587..1352098) Neisseria meningitidis FAM18 4675140 YP_975361.1 CDS NMC1362 NC_008767.1 1352253 1353506 R hypothetical protein complement(1352253..1353506) Neisseria meningitidis FAM18 4676337 YP_975362.1 CDS NMC1363 NC_008767.1 1353781 1355760 D aminopeptidase 1353781..1355760 Neisseria meningitidis FAM18 4675178 YP_975363.1 CDS porA NC_008767.1 1356569 1357726 R porin complement(1356569..1357726) Neisseria meningitidis FAM18 4675179 YP_975364.1 CDS greA NC_008767.1 1358694 1359170 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1358694..1359170) Neisseria meningitidis FAM18 4676063 YP_975365.1 CDS aroA NC_008767.1 1359565 1360866 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1359565..1360866 Neisseria meningitidis FAM18 4676536 YP_975366.1 CDS NMC1367 NC_008767.1 1360909 1361442 R lipoprotein complement(1360909..1361442) Neisseria meningitidis FAM18 4675591 YP_975367.1 CDS NMC1368 NC_008767.1 1361650 1363227 R phopholipase D-family protein complement(1361650..1363227) Neisseria meningitidis FAM18 4675498 YP_975368.1 CDS NMC1370 NC_008767.1 1363288 1364796 R hypothetical protein complement(1363288..1364796) Neisseria meningitidis FAM18 4675499 YP_975369.1 CDS NMC1371 NC_008767.1 1364978 1365757 D hypothetical protein 1364978..1365757 Neisseria meningitidis FAM18 4675923 YP_975370.1 CDS NMC1372 NC_008767.1 1365754 1366455 D hypothetical protein 1365754..1366455 Neisseria meningitidis FAM18 4675924 YP_975371.1 CDS NMC1373 NC_008767.1 1366452 1367906 D iron-sulfur protein 1366452..1367906 Neisseria meningitidis FAM18 4675353 YP_975372.1 CDS purE NC_008767.1 1368089 1368574 R phosphoribosylaminoimidazole carboxylase catalytic subunit complement(1368089..1368574) Neisseria meningitidis FAM18 4675354 YP_975373.1 CDS NMC1375 NC_008767.1 1368623 1369339 R hypothetical protein complement(1368623..1369339) Neisseria meningitidis FAM18 4675367 YP_975374.1 CDS NMC1376 NC_008767.1 1369339 1370007 R methyltransferase complement(1369339..1370007) Neisseria meningitidis FAM18 4675357 YP_975375.1 CDS mutL NC_008767.1 1370347 1372323 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1370347..1372323 Neisseria meningitidis FAM18 4675358 YP_975376.1 CDS dnaZX NC_008767.1 1372418 1374547 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1372418..1374547 Neisseria meningitidis FAM18 4676261 YP_975377.1 CDS NMC1380 NC_008767.1 1374627 1374962 D hypothetical protein 1374627..1374962 Neisseria meningitidis FAM18 4675928 YP_975378.1 CDS NMC1381 NC_008767.1 1377014 1377979 D transposase for IS1655 1377014..1377979 Neisseria meningitidis FAM18 4675523 YP_975379.1 CDS recA NC_008767.1 1378364 1379410 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1378364..1379410) Neisseria meningitidis FAM18 4675524 YP_975380.1 CDS aroD NC_008767.1 1379631 1380428 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1379631..1380428 Neisseria meningitidis FAM18 4675764 YP_975381.1 CDS rep NC_008767.1 1380391 1382463 D ATP-dependent DNA helicase 1380391..1382463 Neisseria meningitidis FAM18 4675502 YP_975382.1 CDS NMC1386 NC_008767.1 1382716 1383774 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(1382716..1383774) Neisseria meningitidis FAM18 4675725 YP_975383.1 CDS NMC1389 NC_008767.1 1385612 1386391 D ferredoxin NADP+ reductase 1385612..1386391 Neisseria meningitidis FAM18 4675451 YP_975384.1 CDS NMC1391 NC_008767.1 1386601 1388013 R DNA polymerase III subunit complement(1386601..1388013) Neisseria meningitidis FAM18 4675445 YP_975385.1 CDS NMC1392 NC_008767.1 1388831 1390006 D hypothetical protein 1388831..1390006 Neisseria meningitidis FAM18 4675446 YP_975386.1 CDS NMC1393 NC_008767.1 1390217 1390765 R hypothetical protein complement(1390217..1390765) Neisseria meningitidis FAM18 4675369 YP_975387.1 CDS NMC1394 NC_008767.1 1390768 1392264 R ferredoxin complement(1390768..1392264) Neisseria meningitidis FAM18 4675370 YP_975388.1 CDS tkt NC_008767.1 1392793 1394772 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1392793..1394772 Neisseria meningitidis FAM18 4675506 YP_975389.1 CDS fumC NC_008767.1 1394920 1396308 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1394920..1396308 Neisseria meningitidis FAM18 4675194 YP_975390.1 CDS NMC1397 NC_008767.1 1396373 1397296 R hypothetical protein complement(1396373..1397296) Neisseria meningitidis FAM18 4676647 YP_975391.1 CDS ssb NC_008767.1 1397821 1398345 R ssDNA-binding protein complement(1397821..1398345) Neisseria meningitidis FAM18 4675507 YP_975392.1 CDS NMC1400 NC_008767.1 1398349 1399734 R integral membrane transporter complement(1398349..1399734) Neisseria meningitidis FAM18 4675007 YP_975393.1 CDS NMC1401 NC_008767.1 1399842 1400465 R transglycosylase complement(1399842..1400465) Neisseria meningitidis FAM18 4675496 YP_975394.1 CDS NMC1402 NC_008767.1 1401610 1402101 R hypothetical protein complement(1401610..1402101) Neisseria meningitidis FAM18 4675497 YP_975395.1 CDS opaA NC_008767.1 1403533 1404333 R hypothetical protein complement(1403533..1404333) Neisseria meningitidis FAM18 4675483 YP_975396.1 CDS NMC1404 NC_008767.1 1405344 1406075 D hypothetical protein 1405344..1406075 Neisseria meningitidis FAM18 4676167 YP_975397.1 CDS NMC1405 NC_008767.1 1406192 1407700 D exopolyphosphatase 1406192..1407700 Neisseria meningitidis FAM18 4675484 YP_975398.1 CDS NMC1407 NC_008767.1 1408594 1408935 R hypothetical protein complement(1408594..1408935) Neisseria meningitidis FAM18 4676368 YP_975399.1 CDS trpS NC_008767.1 1408941 1409951 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1408941..1409951) Neisseria meningitidis FAM18 4676369 YP_975400.1 CDS clpB NC_008767.1 1410212 1412791 D ClpB protein 1410212..1412791 Neisseria meningitidis FAM18 4674814 YP_975401.1 CDS NMC1410 NC_008767.1 1412878 1414092 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase complement(1412878..1414092) Neisseria meningitidis FAM18 4676695 YP_975402.1 CDS NMC1411 NC_008767.1 1414181 1414390 R tautomerase complement(1414181..1414390) Neisseria meningitidis FAM18 4676366 YP_975403.1 CDS NMC1412 NC_008767.1 1414735 1415541 D hypothetical protein 1414735..1415541 Neisseria meningitidis FAM18 4676367 YP_975404.1 CDS NMC1413 NC_008767.1 1415599 1416864 R glutamate dehydrogenase complement(1415599..1416864) Neisseria meningitidis FAM18 4675519 YP_975405.1 CDS NMC1414 NC_008767.1 1417271 1417981 D catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 1417271..1417981 Neisseria meningitidis FAM18 4675520 YP_975406.1 CDS recX NC_008767.1 1418054 1418515 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1418054..1418515 Neisseria meningitidis FAM18 4675651 YP_975407.1 CDS NMC1417 NC_008767.1 1418903 1419385 D acyl-CoA hydrolase 1418903..1419385 Neisseria meningitidis FAM18 4675652 YP_975408.1 CDS NMC1418 NC_008767.1 1419745 1420992 R membrane peptidase complement(1419745..1420992) Neisseria meningitidis FAM18 4675168 YP_975409.1 CDS surE NC_008767.1 1421248 1421994 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(1421248..1421994) Neisseria meningitidis FAM18 4675169 YP_975410.1 CDS NMC1420 NC_008767.1 1422011 1423567 R hypothetical protein complement(1422011..1423567) Neisseria meningitidis FAM18 4675210 YP_975411.1 CDS NMC1422 NC_008767.1 1423935 1424723 R fimbrial assembly protein complement(1423935..1424723) Neisseria meningitidis FAM18 4675616 YP_975412.1 CDS gabD NC_008767.1 1424832 1426265 R succinate semialdehyde dehydrogenase complement(1424832..1426265) Neisseria meningitidis FAM18 4675617 YP_975413.1 CDS NMC1424 NC_008767.1 1426906 1427235 D hypothetical protein 1426906..1427235 Neisseria meningitidis FAM18 4676669 YP_975414.1 CDS NMC1425 NC_008767.1 1427368 1427748 R lipoprotein complement(1427368..1427748) Neisseria meningitidis FAM18 4675534 YP_975415.1 CDS NMC1426 NC_008767.1 1428224 1430305 D integral membrane protein (CstA-like) 1428224..1430305 Neisseria meningitidis FAM18 4675535 YP_975416.1 CDS NMC1428 NC_008767.1 1431830 1434595 D outer membrane substrate binding protein 1431830..1434595 Neisseria meningitidis FAM18 4675508 YP_975417.1 CDS lysC NC_008767.1 1436088 1437305 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(1436088..1437305) Neisseria meningitidis FAM18 4675509 YP_975418.1 CDS rph NC_008767.1 1437507 1438235 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(1437507..1438235) Neisseria meningitidis FAM18 4676336 YP_975419.1 CDS NMC1431 NC_008767.1 1438317 1438781 R hypothetical protein complement(1438317..1438781) Neisseria meningitidis FAM18 4675412 YP_975420.1 CDS NMC1432 NC_008767.1 1438998 1439774 D hypothetical protein 1438998..1439774 Neisseria meningitidis FAM18 4675525 YP_975421.1 CDS NMC1433 NC_008767.1 1440019 1440873 D hypothetical protein 1440019..1440873 Neisseria meningitidis FAM18 4675526 YP_975422.1 CDS pncB NC_008767.1 1440863 1442122 D catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1440863..1442122 Neisseria meningitidis FAM18 4675561 YP_975423.1 CDS argS NC_008767.1 1442214 1443932 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1442214..1443932 Neisseria meningitidis FAM18 4675953 YP_975424.1 CDS NMC1437 NC_008767.1 1444447 1445904 D hypothetical protein 1444447..1445904 Neisseria meningitidis FAM18 4676240 YP_975425.1 CDS NMC1438 NC_008767.1 1446841 1447587 R binding-protein-dependent transport systems inner membrane protein complement(1446841..1447587) Neisseria meningitidis FAM18 4675562 YP_975426.1 CDS NMC1439 NC_008767.1 1447766 1448467 R nuclease complement(1447766..1448467) Neisseria meningitidis FAM18 4675628 YP_975427.1 CDS rpiA NC_008767.1 1448506 1449177 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(1448506..1449177) Neisseria meningitidis FAM18 4675629 YP_975428.1 CDS ispF NC_008767.1 1449254 1449736 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(1449254..1449736) Neisseria meningitidis FAM18 4675402 YP_975429.1 CDS ispD NC_008767.1 1449768 1450457 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(1449768..1450457) Neisseria meningitidis FAM18 4675569 YP_975430.1 CDS dnaQ NC_008767.1 1450454 1451215 R DNA polymerase III subunit epsilon complement(1450454..1451215) Neisseria meningitidis FAM18 4675570 YP_975431.1 CDS NMC1444 NC_008767.1 1451346 1452656 R hypothetical protein complement(1451346..1452656) Neisseria meningitidis FAM18 4675926 YP_975432.1 CDS NMC1445 NC_008767.1 1452646 1452834 R hypothetical protein complement(1452646..1452834) Neisseria meningitidis FAM18 4675653 YP_975433.1 CDS NMC1446 NC_008767.1 1452831 1453130 R hypothetical protein complement(1452831..1453130) Neisseria meningitidis FAM18 4675654 YP_975434.1 CDS ackA1 NC_008767.1 1453451 1454677 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1453451..1454677 Neisseria meningitidis FAM18 4675571 YP_975435.1 CDS dipZ NC_008767.1 1455193 1457034 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(1455193..1457034) Neisseria meningitidis FAM18 4676166 YP_975436.1 CDS NMC1449 NC_008767.1 1457125 1457595 D hypothetical protein 1457125..1457595 Neisseria meningitidis FAM18 4675572 YP_975437.1 CDS NMC1450 NC_008767.1 1457666 1458493 R transferase complement(1457666..1458493) Neisseria meningitidis FAM18 4675144 YP_975438.1 CDS NMC1451 NC_008767.1 1458565 1459047 R peptidyl-prolyl isomerase complement(1458565..1459047) Neisseria meningitidis FAM18 4675145 YP_975439.1 CDS NMC1452 NC_008767.1 1459536 1459853 D hypothetical protein 1459536..1459853 Neisseria meningitidis FAM18 4676566 YP_975440.1 CDS NMC1453 NC_008767.1 1459911 1461278 D hypothetical protein 1459911..1461278 Neisseria meningitidis FAM18 4676567 YP_975441.1 CDS NMC1454 NC_008767.1 1461459 1463403 R virulence associated protein complement(join(1461459..1463300,1463299..1463403)) Neisseria meningitidis FAM18 4676559 YP_975442.1 CDS smpB NC_008767.1 1463876 1464328 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1463876..1464328) Neisseria meningitidis FAM18 4676560 YP_975443.1 CDS rfaF NC_008767.1 1464377 1465387 R ADP-heptose--LPS heptosyltransferase complement(1464377..1465387) Neisseria meningitidis FAM18 4675030 YP_975444.1 CDS NMC1457 NC_008767.1 1465970 1466839 R methylated-DNA-protein-cysteine methyltransferase complement(1465970..1466839) Neisseria meningitidis FAM18 4675733 YP_975445.1 CDS NMC1458 NC_008767.1 1466997 1467557 D hypothetical protein 1466997..1467557 Neisseria meningitidis FAM18 4676690 YP_975446.1 CDS dapE NC_008767.1 1468297 1469442 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(1468297..1469442) Neisseria meningitidis FAM18 4676691 YP_975447.1 CDS NMC1460 NC_008767.1 1469555 1470175 R hypothetical protein complement(1469555..1470175) Neisseria meningitidis FAM18 4675962 YP_975448.1 CDS NMC1461 NC_008767.1 1470209 1470739 R hypothetical protein complement(1470209..1470739) Neisseria meningitidis FAM18 4676613 YP_975449.1 CDS NMC1462 NC_008767.1 1470813 1471418 R hypothetical protein complement(1470813..1471418) Neisseria meningitidis FAM18 4676614 YP_975450.1 CDS secA NC_008767.1 1472198 1474948 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1472198..1474948 Neisseria meningitidis FAM18 4676639 YP_975451.1 CDS dnaG NC_008767.1 1475094 1476866 D synthesizes RNA primers at the replication forks; DNA primase 1475094..1476866 Neisseria meningitidis FAM18 4675103 YP_975452.1 CDS rpoD NC_008767.1 1477006 1478982 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1477006..1478982 Neisseria meningitidis FAM18 4675958 YP_975453.1 CDS lbpA NC_008767.1 1481777 1484608 R lactoferrin binding protein A complement(1481777..1484608) Neisseria meningitidis FAM18 4676640 YP_975454.1 CDS lbpB NC_008767.1 1484605 1486782 R lactoferrin-binding protein complement(1484605..1486782) Neisseria meningitidis FAM18 4676403 YP_975455.1 CDS NMC1470 NC_008767.1 1489378 1489662 R it misses that part: MSTFFRQTAQA, when compared to the homologous sequences, but there is a substitution of M -> R, thus cannot be extended; remnant of transposase from insertion element IS1106A2 (fragment) complement(1489378..1489662) Neisseria meningitidis FAM18 4676404 YP_975456.1 CDS pyrG NC_008767.1 1489911 1491545 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(1489911..1491545) Neisseria meningitidis FAM18 4676653 YP_975457.1 CDS fadD NC_008767.1 1491657 1493327 R long-chain-fatty-acid--CoA-ligase complement(1491657..1493327) Neisseria meningitidis FAM18 4675778 YP_975458.1 CDS mnmA NC_008767.1 1493398 1494501 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1493398..1494501) Neisseria meningitidis FAM18 4675275 YP_975459.1 CDS NMC1474 NC_008767.1 1494627 1495100 R hypothetical protein complement(1494627..1495100) Neisseria meningitidis FAM18 4674832 YP_975460.1 CDS dgk NC_008767.1 1495215 1495598 R diacylglycerol kinase complement(1495215..1495598) Neisseria meningitidis FAM18 4676654 YP_975461.1 CDS gshB NC_008767.1 1495910 1496869 R catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase complement(1495910..1496869) Neisseria meningitidis FAM18 4675968 YP_975462.1 CDS glnS NC_008767.1 1496959 1498680 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(1496959..1498680) Neisseria meningitidis FAM18 4676512 YP_975463.1 CDS glpR NC_008767.1 1498759 1499532 R glycerol 3-phosphate regulon repressor complement(1498759..1499532) Neisseria meningitidis FAM18 4676603 YP_975464.1 CDS NMC1480 NC_008767.1 1499575 1500477 R hypothetical protein complement(1499575..1500477) Neisseria meningitidis FAM18 4676598 YP_975465.1 CDS NMC1481 NC_008767.1 1500626 1501342 R GntR family transcriptional regulator complement(1500626..1501342) Neisseria meningitidis FAM18 4675639 YP_975466.1 CDS NMC1483 NC_008767.1 1501911 1502333 R hypothetical protein complement(1501911..1502333) Neisseria meningitidis FAM18 4675640 YP_975467.1 CDS NMC1485 NC_008767.1 1502451 1503122 R hypothetical protein complement(1502451..1503122) Neisseria meningitidis FAM18 4676587 YP_975468.1 CDS purN NC_008767.1 1503138 1503764 R phosphoribosylglycinamide transformylase complement(1503138..1503764) Neisseria meningitidis FAM18 4676588 YP_975469.1 CDS NMC1487 NC_008767.1 1503871 1504677 R peptidyl-prolyl isomerase complement(1503871..1504677) Neisseria meningitidis FAM18 4676029 YP_975470.1 CDS holC NC_008767.1 1504936 1505376 R DNA polymerase III subunit chi complement(1504936..1505376) Neisseria meningitidis FAM18 4675641 YP_975471.1 CDS pepA NC_008767.1 1505439 1506845 R aminopeptidase complement(1505439..1506845) Neisseria meningitidis FAM18 4676421 YP_975472.1 CDS NMC1490 NC_008767.1 1507015 1508130 D hypothetical protein 1507015..1508130 Neisseria meningitidis FAM18 4676106 YP_975473.1 CDS NMC1491 NC_008767.1 1508127 1509197 D hypothetical protein 1508127..1509197 Neisseria meningitidis FAM18 4675642 YP_975474.1 CDS acnB NC_008767.1 1509508 1512093 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 1509508..1512093 Neisseria meningitidis FAM18 4675831 YP_975475.1 CDS argF NC_008767.1 1512235 1513230 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 1512235..1513230 Neisseria meningitidis FAM18 4675347 YP_975476.1 CDS ilvC NC_008767.1 1513454 1514467 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(1513454..1514467) Neisseria meningitidis FAM18 4676444 YP_975477.1 CDS NMC1495 NC_008767.1 1514547 1514840 R hypothetical protein complement(1514547..1514840) Neisseria meningitidis FAM18 4676442 YP_975478.1 CDS ilvH NC_008767.1 1514907 1515398 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(1514907..1515398) Neisseria meningitidis FAM18 4675832 YP_975479.1 CDS ilvI NC_008767.1 1515409 1517136 R acetolactate synthase isozyme III large subunit complement(1515409..1517136) Neisseria meningitidis FAM18 4676427 YP_975480.1 CDS NMC1498 NC_008767.1 1518257 1518910 D lipoprotein 1518257..1518910 Neisseria meningitidis FAM18 4676428 YP_975481.1 CDS hisG NC_008767.1 1518989 1519642 D short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 1518989..1519642 Neisseria meningitidis FAM18 4675655 YP_975482.1 CDS NMC1500 NC_008767.1 1519746 1520645 D hypothetical protein 1519746..1520645 Neisseria meningitidis FAM18 4676429 YP_975483.1 CDS hisD NC_008767.1 1520642 1521931 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1520642..1521931 Neisseria meningitidis FAM18 4675656 YP_975484.1 CDS hisC NC_008767.1 1521977 1523074 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1521977..1523074 Neisseria meningitidis FAM18 4676432 YP_975485.2 CDS hisB NC_008767.1 1523254 1523988 D catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1523254..1523988 Neisseria meningitidis FAM18 4676431 YP_975486.1 CDS NMC1504 NC_008767.1 1524083 1524952 D hypothetical protein 1524083..1524952 Neisseria meningitidis FAM18 4676477 YP_975487.1 CDS NMC1505 NC_008767.1 1525230 1525592 D transcriptional regulator 1525230..1525592 Neisseria meningitidis FAM18 4675649 YP_975488.1 CDS NMC1506 NC_008767.1 1525623 1526627 D transposase for IS1106A3 1525623..1526627 Neisseria meningitidis FAM18 4675650 YP_975489.1 CDS NMC1507 NC_008767.1 1526895 1527758 D hypothetical protein 1526895..1527758 Neisseria meningitidis FAM18 4675815 YP_975490.1 CDS NMC1508 NC_008767.1 1527809 1528861 R SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease complement(1527809..1528861) Neisseria meningitidis FAM18 4675816 YP_975491.1 CDS pgsA NC_008767.1 1529708 1530271 R CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(1529708..1530271) Neisseria meningitidis FAM18 4675637 YP_975492.1 CDS NMC1511 NC_008767.1 1530498 1530800 R hypothetical protein complement(1530498..1530800) Neisseria meningitidis FAM18 4676041 YP_975493.1 CDS NMC1512 NC_008767.1 1531131 1531466 R hypothetical protein complement(1531131..1531466) Neisseria meningitidis FAM18 4675638 YP_975494.1 CDS NMC1513 NC_008767.1 1531595 1532500 D AraC family transcriptional regulator 1531595..1532500 Neisseria meningitidis FAM18 4675761 YP_975495.1 CDS NMC1514 NC_008767.1 1532562 1533137 R hypothetical protein complement(1532562..1533137) Neisseria meningitidis FAM18 4675762 YP_975496.1 CDS NMC1515 NC_008767.1 1533197 1534099 D hypothetical protein 1533197..1534099 Neisseria meningitidis FAM18 4675750 YP_975497.1 CDS NMC1516 NC_008767.1 1534140 1535270 R polyamine permease substrate-binding protein complement(1534140..1535270) Neisseria meningitidis FAM18 4675751 YP_975498.1 CDS alaS NC_008767.1 1535475 1538099 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1535475..1538099 Neisseria meningitidis FAM18 4675666 YP_975499.1 CDS NMC1519 NC_008767.1 1538188 1539210 R hypothetical protein complement(1538188..1539210) Neisseria meningitidis FAM18 4676384 YP_975500.1 CDS NMC1520 NC_008767.1 1539264 1540415 R C-5 cytosine-specific DNA methylase complement(1539264..1540415) Neisseria meningitidis FAM18 4675667 YP_975501.1 CDS NMC1523 NC_008767.1 1543413 1544357 D potassium-tellurite ethidium and proflavin transporter 1543413..1544357 Neisseria meningitidis FAM18 4675768 YP_975502.1 CDS gpmA NC_008767.1 1544431 1545114 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(1544431..1545114) Neisseria meningitidis FAM18 4675769 YP_975503.1 CDS parC NC_008767.1 1545417 1547714 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1545417..1547714 Neisseria meningitidis FAM18 4676521 YP_975504.1 CDS NMC1526 NC_008767.1 1547734 1549251 D two component sensor kinase 1547734..1549251 Neisseria meningitidis FAM18 4676174 YP_975505.1 CDS NMC1527 NC_008767.1 1549303 1549770 D two component response regulator 1549303..1549770 Neisseria meningitidis FAM18 4675720 YP_975506.1 CDS NMC1528 NC_008767.1 1549874 1550626 D hypothetical protein 1549874..1550626 Neisseria meningitidis FAM18 4675721 YP_975507.1 CDS metZ NC_008767.1 1552367 1553536 R O-succinylhomoserine sulfhydrolase complement(1552367..1553536) Neisseria meningitidis FAM18 4675833 YP_975508.1 CDS NMC1531 NC_008767.1 1553834 1554595 R hypothetical protein complement(1553834..1554595) Neisseria meningitidis FAM18 4676273 YP_975509.1 CDS NMC1532 NC_008767.1 1554695 1554946 D hypothetical protein 1554695..1554946 Neisseria meningitidis FAM18 4675834 YP_975510.1 CDS hisJ NC_008767.1 1554998 1555804 D histidine-binding periplasmic protein 1554998..1555804 Neisseria meningitidis FAM18 4675807 YP_975511.1 CDS fumA NC_008767.1 1555994 1557634 D fumarate hydratase 1555994..1557634 Neisseria meningitidis FAM18 4676453 YP_975512.1 CDS trkA NC_008767.1 1557732 1559144 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1557732..1559144 Neisseria meningitidis FAM18 4676636 YP_975513.1 CDS NMC1536 NC_008767.1 1559477 1560364 R insertion element is1655 transposase (fragment) complement(1559477..1560364) Neisseria meningitidis FAM18 4675191 YP_975514.1 CDS thiD NC_008767.1 1561494 1562300 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(1561494..1562300) Neisseria meningitidis FAM18 4675808 YP_975515.1 CDS rnhA NC_008767.1 1564531 1564968 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1564531..1564968 Neisseria meningitidis FAM18 4675718 YP_975516.1 CDS NMC1545 NC_008767.1 1566542 1566946 D hypothetical protein 1566542..1566946 Neisseria meningitidis FAM18 4675574 YP_975517.1 CDS NMC1546 NC_008767.1 1566986 1568170 D hypothetical protein 1566986..1568170 Neisseria meningitidis FAM18 4675719 YP_975518.1 CDS gpxA NC_008767.1 1568233 1568766 R glutathione peroxidase complement(1568233..1568766) Neisseria meningitidis FAM18 4675792 YP_975519.1 CDS nor NC_008767.1 1568945 1571200 R nitric oxide reductase complement(join(1568945..1570915,1570919..1571200)) Neisseria meningitidis FAM18 4676535 YP_975520.1 CDS aniA NC_008767.1 1571574 1572733 D nitrite reductase, major outer membrane copper-containing protein join(1571574..1571825,1571825..1572733) Neisseria meningitidis FAM18 4676222 YP_975521.1 CDS NMC1550 NC_008767.1 1572858 1573613 D hypothetical protein 1572858..1573613 Neisseria meningitidis FAM18 4676465 YP_975522.1 CDS opaB NC_008767.1 1574776 1575569 D hypothetical protein join(1574776..1574811,1574811..1575569) Neisseria meningitidis FAM18 4675793 YP_975523.1 CDS NMC1552 NC_008767.1 1575770 1576327 R hypothetical protein complement(1575770..1576327) Neisseria meningitidis FAM18 4676168 YP_975524.1 CDS NMC1553 NC_008767.1 1576403 1578037 R hypothetical protein complement(1576403..1578037) Neisseria meningitidis FAM18 4675825 YP_975525.1 CDS serC NC_008767.1 1578318 1579424 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(1578318..1579424) Neisseria meningitidis FAM18 4675826 YP_975526.1 CDS NMC1555 NC_008767.1 1579789 1580220 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1579789..1580220 Neisseria meningitidis FAM18 4675093 YP_975527.1 CDS nusA NC_008767.1 1580233 1581750 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1580233..1581750 Neisseria meningitidis FAM18 4675993 YP_975528.1 CDS infB NC_008767.1 1581762 1584650 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1581762..1584650 Neisseria meningitidis FAM18 4676182 YP_975529.1 CDS NMC1558 NC_008767.1 1584862 1586256 R hypothetical protein complement(1584862..1586256) Neisseria meningitidis FAM18 4675972 YP_975530.1 CDS NMC1559 NC_008767.1 1586330 1587670 R hypothetical protein complement(1586330..1587670) Neisseria meningitidis FAM18 4675994 YP_975531.1 CDS NMC1560 NC_008767.1 1587813 1588439 D hemolysin 1587813..1588439 Neisseria meningitidis FAM18 4675819 YP_975532.1 CDS NMC1562 NC_008767.1 1588503 1589921 R sodium:alanine symporter complement(1588503..1589921) Neisseria meningitidis FAM18 4675820 YP_975533.1 CDS NMC1563 NC_008767.1 1590248 1590976 D hypothetical protein 1590248..1590976 Neisseria meningitidis FAM18 4675828 YP_975534.1 CDS NMC1564 NC_008767.1 1591035 1591724 R disulfide bond formation protein complement(1591035..1591724) Neisseria meningitidis FAM18 4675829 YP_975535.1 CDS NMC1566 NC_008767.1 1592281 1592745 R transcription regulator AsnC complement(1592281..1592745) Neisseria meningitidis FAM18 4675891 YP_975536.1 CDS alr NC_008767.1 1593070 1594128 D alanine racemase 1593070..1594128 Neisseria meningitidis FAM18 4675892 YP_975537.1 CDS NMC1568 NC_008767.1 1594192 1595547 R hypothetical protein complement(1594192..1595547) Neisseria meningitidis FAM18 4676478 YP_975538.1 CDS NMC1569 NC_008767.1 1595563 1595835 R ACT domain-containing protein; hypothetical protein complement(1595563..1595835) Neisseria meningitidis FAM18 4675999 YP_975539.1 CDS NMC1570 NC_008767.1 1595961 1596698 R hypothetical protein complement(1595961..1596698) Neisseria meningitidis FAM18 4676000 YP_975540.1 CDS NMC1571 NC_008767.1 1596979 1597890 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(1596979..1597890) Neisseria meningitidis FAM18 4675857 YP_975541.1 CDS NMC1572 NC_008767.1 1598023 1598616 D hypothetical protein 1598023..1598616 Neisseria meningitidis FAM18 4675858 YP_975542.1 CDS NMC1573 NC_008767.1 1598728 1599348 D hypothetical protein 1598728..1599348 Neisseria meningitidis FAM18 4675881 YP_975543.1 CDS NMC1574 NC_008767.1 1599279 1599743 R DNA transport competence protein complement(1599279..1599743) Neisseria meningitidis FAM18 4675882 YP_975544.1 CDS NMC1576 NC_008767.1 1605612 1606796 D hypothetical protein 1605612..1606796 Neisseria meningitidis FAM18 4675965 YP_975545.1 CDS spoT NC_008767.1 1606863 1609019 R guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase complement(1606863..1609019) Neisseria meningitidis FAM18 4675966 YP_975546.1 CDS rpoZ NC_008767.1 1609112 1609318 R DNA-directed RNA polymerase subunit omega complement(1609112..1609318) Neisseria meningitidis FAM18 4675212 YP_975547.1 CDS gmk NC_008767.1 1609377 1609994 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1609377..1609994) Neisseria meningitidis FAM18 4675317 YP_975548.1 CDS apt NC_008767.1 1610122 1610721 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1610122..1610721 Neisseria meningitidis FAM18 4676526 YP_975549.1 CDS NMC1581 NC_008767.1 1610767 1611555 R hypothetical protein complement(1610767..1611555) Neisseria meningitidis FAM18 4676423 YP_975550.1 CDS NMC1582 NC_008767.1 1611880 1613235 D protease 1611880..1613235 Neisseria meningitidis FAM18 4675908 YP_975551.1 CDS NMC1583 NC_008767.1 1613369 1613845 D hypothetical protein 1613369..1613845 Neisseria meningitidis FAM18 4675909 YP_975552.1 CDS NMC1584 NC_008767.1 1614450 1614836 R hypothetical protein complement(1614450..1614836) Neisseria meningitidis FAM18 4675918 YP_975553.1 CDS NMC1585 NC_008767.1 1614833 1615078 R hypothetical protein complement(1614833..1615078) Neisseria meningitidis FAM18 4675919 YP_975554.1 CDS hmbR NC_008767.1 1615450 1617829 R hypothetical protein complement(join(1615450..1616667,1616666..1617829)) Neisseria meningitidis FAM18 4675914 YP_975555.1 CDS hemO NC_008767.1 1618004 1618696 R heme utilisation protein complement(1618004..1618696) Neisseria meningitidis FAM18 4676343 YP_975556.1 CDS NMC1588 NC_008767.1 1619127 1620431 D hypothetical protein 1619127..1620431 Neisseria meningitidis FAM18 4675851 YP_975557.1 CDS NMC1589 NC_008767.1 1620424 1622064 D hypothetical protein 1620424..1622064 Neisseria meningitidis FAM18 4675915 YP_975558.1 CDS NMC1590 NC_008767.1 1622064 1622582 D lipoprotein 1622064..1622582 Neisseria meningitidis FAM18 4675722 YP_975559.1 CDS tag NC_008767.1 1622586 1623137 D DNA-3-methyladenine glycosylase I 1622586..1623137 Neisseria meningitidis FAM18 4675723 YP_975560.1 CDS NMC1592 NC_008767.1 1623145 1623768 D lipase 1623145..1623768 Neisseria meningitidis FAM18 4674942 YP_975561.1 CDS NMC1593 NC_008767.1 1623990 1624298 D hypothetical protein 1623990..1624298 Neisseria meningitidis FAM18 4675843 YP_975562.1 CDS gcvP NC_008767.1 1624329 1627181 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 1624329..1627181 Neisseria meningitidis FAM18 4675844 YP_975563.1 CDS NMC1595 NC_008767.1 1627646 1628485 R cytochrome complement(1627646..1628485) Neisseria meningitidis FAM18 4676634 YP_975564.1 CDS tyrB NC_008767.1 1628910 1630103 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1628910..1630103) Neisseria meningitidis FAM18 4675895 YP_975565.1 CDS trmA NC_008767.1 1630109 1631212 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(1630109..1631212) Neisseria meningitidis FAM18 4676482 YP_975566.1 CDS aroC NC_008767.1 1631355 1632455 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1631355..1632455 Neisseria meningitidis FAM18 4675192 YP_975567.1 CDS NMC1599 NC_008767.1 1632546 1632971 D hypothetical protein 1632546..1632971 Neisseria meningitidis FAM18 4675501 YP_975568.1 CDS parE NC_008767.1 1633045 1635030 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1633045..1635030) Neisseria meningitidis FAM18 4675896 YP_975569.1 CDS NMC1601 NC_008767.1 1635097 1635621 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(1635097..1635621) Neisseria meningitidis FAM18 4676175 YP_975570.1 CDS serS NC_008767.1 1635786 1637081 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1635786..1637081 Neisseria meningitidis FAM18 4675860 YP_975571.1 CDS ldhA NC_008767.1 1637159 1638160 R D-lactate dehydrogenase complement(1637159..1638160) Neisseria meningitidis FAM18 4675082 YP_975572.1 CDS prfA NC_008767.1 1638282 1639358 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1638282..1639358) Neisseria meningitidis FAM18 4676407 YP_975573.1 CDS NMC1605 NC_008767.1 1639448 1640272 R hypothetical protein complement(1639448..1640272) Neisseria meningitidis FAM18 4676066 YP_975574.1 CDS ans NC_008767.1 1640221 1641213 R L-asparaginase complement(1640221..1641213) Neisseria meningitidis FAM18 4675861 YP_975575.1 CDS NMC1607 NC_008767.1 1641280 1641963 R DedA family integral membrane protein complement(1641280..1641963) Neisseria meningitidis FAM18 4676466 YP_975576.1 CDS glmM NC_008767.1 1642152 1643486 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1642152..1643486) Neisseria meningitidis FAM18 4675873 YP_975577.1 CDS dhpS NC_008767.1 1643616 1644467 R dihydropteroate synthase complement(1643616..1644467) Neisseria meningitidis FAM18 4675874 YP_975578.1 CDS NMC1610 NC_008767.1 1644634 1646856 D hypothetical protein 1644634..1646856 Neisseria meningitidis FAM18 4675975 YP_975579.1 CDS NMC1611 NC_008767.1 1646921 1648405 R 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1646921..1648405) Neisseria meningitidis FAM18 4675862 YP_975580.1 CDS NMC1613 NC_008767.1 1648419 1648934 R hypothetical protein complement(1648419..1648934) Neisseria meningitidis FAM18 4675863 YP_975581.1 CDS NMC1614 NC_008767.1 1648941 1649375 R hypothetical protein complement(1648941..1649375) Neisseria meningitidis FAM18 4675864 YP_975582.1 CDS NMC1615 NC_008767.1 1649673 1650107 R hypothetical protein complement(1649673..1650107) Neisseria meningitidis FAM18 4675865 YP_975583.1 CDS NMC1616 NC_008767.1 1650282 1650893 D insertion element IS1016 transposase 1650282..1650893 Neisseria meningitidis FAM18 4675877 YP_975584.1 CDS fabF2 NC_008767.1 1650838 1651974 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase join(1650838..1651560,1651564..1651974) Neisseria meningitidis FAM18 4675878 YP_975585.1 CDS lgtF NC_008767.1 1652172 1652936 D beta-1,4-glucosyltransferase 1652172..1652936 Neisseria meningitidis FAM18 4675840 YP_975586.1 CDS rfaK NC_008767.1 1652937 1654001 D alpha 1,2 N-acetylglucosamine transferase 1652937..1654001 Neisseria meningitidis FAM18 4676380 YP_975587.1 CDS NMC1621 NC_008767.1 1654040 1654210 D hypothetical protein 1654040..1654210 Neisseria meningitidis FAM18 4675559 YP_975588.1 CDS NMC1622 NC_008767.1 1654388 1655725 D integral membrane ion transporter 1654388..1655725 Neisseria meningitidis FAM18 4675868 YP_975589.1 CDS NMC1623 NC_008767.1 1655897 1656557 R hypothetical protein complement(join(1655897..1656298,1656297..1656557)) Neisseria meningitidis FAM18 4675869 YP_975590.1 CDS thyA NC_008767.1 1656566 1657360 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(1656566..1657360) Neisseria meningitidis FAM18 4675170 YP_975591.1 CDS gdhA NC_008767.1 1657744 1659078 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1657744..1659078 Neisseria meningitidis FAM18 4675196 YP_975592.1 CDS NMC1626 NC_008767.1 1659226 1659594 D LOW G+C REGION; hypothetical protein 1659226..1659594 Neisseria meningitidis FAM18 4676618 YP_975593.1 CDS NMC1629 NC_008767.1 1660081 1660863 R GntR family transcriptional regulator complement(1660081..1660863) Neisseria meningitidis FAM18 4675277 YP_975594.1 CDS NMC1630 NC_008767.1 1661395 1661694 D hypothetical protein 1661395..1661694 Neisseria meningitidis FAM18 4675278 YP_975595.1 CDS mtrE NC_008767.1 1662062 1663513 R outer membrane lipoprotein complement(1662062..1663513) Neisseria meningitidis FAM18 4676611 YP_975596.1 CDS mtrD NC_008767.1 1663520 1666723 R drug efflux protein complement(1663520..1666723) Neisseria meningitidis FAM18 4675937 YP_975597.1 CDS mtrC NC_008767.1 1666735 1667973 R membrane fusion protein complement(1666735..1667973) Neisseria meningitidis FAM18 4676291 YP_975598.1 CDS mtrR NC_008767.1 1668381 1669013 D transcriptional regulator 1668381..1669013 Neisseria meningitidis FAM18 4676290 YP_975599.1 CDS NMC1636 NC_008767.1 1669292 1669549 R hypothetical protein complement(1669292..1669549) Neisseria meningitidis FAM18 4675938 YP_975600.1 CDS NMC1637 NC_008767.1 1669838 1671406 D hypothetical protein 1669838..1671406 Neisseria meningitidis FAM18 4676612 YP_975601.1 CDS recC NC_008767.1 1671476 1674685 R exodeoxyribonuclease V complement(1671476..1674685) Neisseria meningitidis FAM18 4676284 YP_975602.1 CDS NMC1639 NC_008767.1 1674786 1676195 R hypothetical protein complement(1674786..1676195) Neisseria meningitidis FAM18 4675754 YP_975603.1 CDS NMC1643 NC_008767.1 1677927 1678538 R CcoO; FixO; cbb3-type cytochrome c oxidase subunit II complement(1677927..1678538) Neisseria meningitidis FAM18 4676471 YP_975604.1 CDS NMC1645 NC_008767.1 1678565 1680010 R CcoN; FixN; cbb3-type cytochrome c oxidase subunit I complement(1678565..1680010) Neisseria meningitidis FAM18 4676472 YP_975605.1 CDS NMC1646 NC_008767.1 1680316 1682073 D hypothetical protein 1680316..1682073 Neisseria meningitidis FAM18 4676679 YP_975606.1 CDS NMC1647 NC_008767.1 1682099 1682566 D hypothetical protein 1682099..1682566 Neisseria meningitidis FAM18 4676680 YP_975607.1 CDS exbD NC_008767.1 1683253 1683687 R biopolymer transport protein complement(1683253..1683687) Neisseria meningitidis FAM18 4676643 YP_975608.1 CDS exbB NC_008767.1 1683690 1684352 R biopolymer transport protein complement(1683690..1684352) Neisseria meningitidis FAM18 4675875 YP_975609.1 CDS tonB NC_008767.1 1684418 1685254 R TonB protein complement(1684418..1685254) Neisseria meningitidis FAM18 4675898 YP_975610.1 CDS NMC1651 NC_008767.1 1685509 1686147 D hypothetical protein 1685509..1686147 Neisseria meningitidis FAM18 4674851 YP_975611.1 CDS NMC1652 NC_008767.1 1686599 1687399 R hypothetical protein complement(1686599..1687399) Neisseria meningitidis FAM18 4676644 YP_975612.1 CDS NMC1653 NC_008767.1 1687535 1688056 R hypothetical protein complement(1687535..1688056) Neisseria meningitidis FAM18 4676651 YP_975613.1 CDS grxB NC_008767.1 1688378 1689022 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1688378..1689022) Neisseria meningitidis FAM18 4676652 YP_975614.1 CDS relA NC_008767.1 1689347 1691560 D GTP pyrophosphokinase 1689347..1691560 Neisseria meningitidis FAM18 4676528 YP_975615.1 CDS natC NC_008767.1 1692854 1694257 R periplasmic type I secretion system protein complement(1692854..1694257) Neisseria meningitidis FAM18 4676659 YP_975616.1 CDS NMC1658 NC_008767.1 1694326 1695753 R periplasmic type I secretion system protein complement(1694326..1695753) Neisseria meningitidis FAM18 4676237 YP_975617.1 CDS NMC1660 NC_008767.1 1696339 1696845 D hypothetical protein 1696339..1696845 Neisseria meningitidis FAM18 4676660 YP_975618.1 CDS NMC1661 NC_008767.1 1697238 1698272 D hypothetical protein 1697238..1698272 Neisseria meningitidis FAM18 4676583 YP_975619.1 CDS NMC1662 NC_008767.1 1698263 1698607 D hypothetical protein 1698263..1698607 Neisseria meningitidis FAM18 4676584 YP_975620.1 CDS NMC1663 NC_008767.1 1698612 1698809 D hypothetical protein 1698612..1698809 Neisseria meningitidis FAM18 4676396 YP_975621.1 CDS NMC1664 NC_008767.1 1698817 1699101 D hypothetical protein 1698817..1699101 Neisseria meningitidis FAM18 4676397 YP_975622.1 CDS NMC1665 NC_008767.1 1699108 1699386 D hypothetical protein 1699108..1699386 Neisseria meningitidis FAM18 4676645 YP_975623.1 CDS NMC1667 NC_008767.1 1699544 1699831 D hypothetical protein 1699544..1699831 Neisseria meningitidis FAM18 4676646 YP_975624.1 CDS NMC1668 NC_008767.1 1699812 1700210 D cell-surface protein 1699812..1700210 Neisseria meningitidis FAM18 4676624 YP_975625.1 CDS NMC1669 NC_008767.1 1700877 1701236 R hypothetical protein complement(1700877..1701236) Neisseria meningitidis FAM18 4676625 YP_975626.1 CDS NMC1670 NC_008767.1 1701259 1701903 R hypothetical protein complement(1701259..1701903) Neisseria meningitidis FAM18 4676641 YP_975627.1 CDS NMC1671 NC_008767.1 1701905 1702441 R hypothetical protein complement(1701905..1702441) Neisseria meningitidis FAM18 4676642 YP_975628.1 CDS NMC1672 NC_008767.1 1702453 1703550 R hypothetical protein complement(1702453..1703550) Neisseria meningitidis FAM18 4676594 YP_975629.1 CDS NMC1673 NC_008767.1 1703553 1704965 R hypothetical protein complement(1703553..1704965) Neisseria meningitidis FAM18 4676595 YP_975630.1 CDS NMC1674 NC_008767.1 1705209 1706003 R hypothetical protein complement(1705209..1706003) Neisseria meningitidis FAM18 4676557 YP_975631.1 CDS NMC1675 NC_008767.1 1705979 1706626 R hypothetical protein complement(1705979..1706626) Neisseria meningitidis FAM18 4676558 YP_975632.1 CDS bioF NC_008767.1 1706636 1707778 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(1706636..1707778) Neisseria meningitidis FAM18 4676591 YP_975633.1 CDS NMC1677 NC_008767.1 1708001 1709077 D hypothetical protein 1708001..1709077 Neisseria meningitidis FAM18 4676555 YP_975634.1 CDS NMC1679 NC_008767.1 1709284 1710750 R integral membrane transport protein complement(1709284..1710750) Neisseria meningitidis FAM18 4676592 YP_975635.1 CDS speB NC_008767.1 1710948 1711871 R catalyzes the formation of putrescine from agmatine; agmatinase complement(1710948..1711871) Neisseria meningitidis FAM18 4676579 YP_975636.1 CDS speA NC_008767.1 1711970 1713862 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(1711970..1713862) Neisseria meningitidis FAM18 4675211 YP_975637.1 CDS NMC1683 NC_008767.1 1714029 1714313 R hypothetical protein complement(1714029..1714313) Neisseria meningitidis FAM18 4675026 YP_975638.1 CDS aspS NC_008767.1 1714464 1716272 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1714464..1716272) Neisseria meningitidis FAM18 4676580 YP_975639.1 CDS NMC1686 NC_008767.1 1716330 1717067 R hypothetical protein complement(1716330..1717067) Neisseria meningitidis FAM18 4675644 YP_975640.1 CDS rpsT NC_008767.1 1718482 1718745 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(1718482..1718745) Neisseria meningitidis FAM18 4676562 YP_975641.1 CDS NMC1689 NC_008767.1 1719048 1720190 D polyamine permease substrate-binding protein 1719048..1720190 Neisseria meningitidis FAM18 4675129 YP_975642.1 CDS tbpA NC_008767.1 1721463 1724189 R transferrin-binding protein A complement(1721463..1724189) Neisseria meningitidis FAM18 4676563 YP_975643.1 CDS tbpB NC_008767.1 1724276 1726075 R transferrin-binding protein B complement(1724276..1726075) Neisseria meningitidis FAM18 4675205 YP_975644.1 CDS glr NC_008767.1 1727770 1728582 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1727770..1728582) Neisseria meningitidis FAM18 4675206 YP_975645.1 CDS NMC1693 NC_008767.1 1728772 1729233 D hypothetical protein 1728772..1729233 Neisseria meningitidis FAM18 4676599 YP_975646.1 CDS amiC NC_008767.1 1729230 1730480 D N-acetylmuramoyl-L-alanine amidase 1729230..1730480 Neisseria meningitidis FAM18 4676564 YP_975647.1 CDS NMC1695 NC_008767.1 1730544 1731365 D hypothetical protein 1730544..1731365 Neisseria meningitidis FAM18 4676479 YP_975648.1 CDS NMC1697 NC_008767.1 1731666 1732808 R hypothetical protein complement(1731666..1732808) Neisseria meningitidis FAM18 4676539 YP_975649.1 CDS NMC1698 NC_008767.1 1732857 1733279 R secreted protein complement(1732857..1733279) Neisseria meningitidis FAM18 4676540 YP_975650.1 CDS NMC1699 NC_008767.1 1733272 1734081 R MutT-like protein complement(1733272..1734081) Neisseria meningitidis FAM18 4676543 YP_975651.1 CDS acpS NC_008767.1 1734163 1734540 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(1734163..1734540) Neisseria meningitidis FAM18 4676544 YP_975652.1 CDS NMC1701 NC_008767.1 1734740 1735507 R hypothetical protein complement(1734740..1735507) Neisseria meningitidis FAM18 4675517 YP_975653.1 CDS NMC1702 NC_008767.1 1735517 1736449 R hypothetical protein complement(join(1735517..1736056,1736228..1736449)) Neisseria meningitidis FAM18 4676548 YP_975654.1 CDS pdxJ NC_008767.1 1736601 1737329 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(1736601..1737329) Neisseria meningitidis FAM18 4676549 YP_975655.1 CDS recO NC_008767.1 1737353 1738147 R DNA repair protein (recombination protein o) complement(1737353..1738147) Neisseria meningitidis FAM18 4676157 YP_975656.1 CDS pheA NC_008767.1 1738178 1739308 R chorismate mutase complement(1738178..1739308) Neisseria meningitidis FAM18 4675740 YP_975657.1 CDS NMC1706 NC_008767.1 1739344 1740723 R integral membrane efflux protein complement(1739344..1740723) Neisseria meningitidis FAM18 4676111 YP_975658.1 CDS NMC1708 NC_008767.1 1741096 1741980 R hypothetical protein complement(1741096..1741980) Neisseria meningitidis FAM18 4676519 YP_975659.1 CDS NMC1709 NC_008767.1 1743688 1744896 D hypothetical protein 1743688..1744896 Neisseria meningitidis FAM18 4676520 YP_975660.1 CDS NMC1710 NC_008767.1 1744917 1745228 D hypothetical protein 1744917..1745228 Neisseria meningitidis FAM18 4676533 YP_975661.1 CDS NMC1711 NC_008767.1 1745232 1745432 D hypothetical protein 1745232..1745432 Neisseria meningitidis FAM18 4676534 YP_975662.1 CDS NMC1712 NC_008767.1 1745659 1745889 D hypothetical protein 1745659..1745889 Neisseria meningitidis FAM18 4676514 YP_975663.1 CDS NMC1713 NC_008767.1 1745917 1746216 D hypothetical protein 1745917..1746216 Neisseria meningitidis FAM18 4676515 YP_975664.1 CDS NMC1714 NC_008767.1 1746233 1746655 D hypothetical protein 1746233..1746655 Neisseria meningitidis FAM18 4676516 YP_975665.1 CDS NMC1715 NC_008767.1 1746543 1748162 D TspB protein 1746543..1748162 Neisseria meningitidis FAM18 4676517 YP_975666.1 CDS NMC1716 NC_008767.1 1748465 1748749 D hypothetical protein 1748465..1748749 Neisseria meningitidis FAM18 4676488 YP_975667.1 CDS NMC1717 NC_008767.1 1748750 1749937 D hypothetical protein 1748750..1749937 Neisseria meningitidis FAM18 4676489 YP_975668.1 CDS NMC1718 NC_008767.1 1750152 1751108 D transposase 1750152..1751108 Neisseria meningitidis FAM18 4676492 YP_975669.1 CDS NMC1719 NC_008767.1 1751514 1752332 D Opa1800 outer membrane protein 1751514..1752332 Neisseria meningitidis FAM18 4676493 YP_975670.1 CDS NMC1720 NC_008767.1 1754168 1754980 R hypothetical protein complement(1754168..1754980) Neisseria meningitidis FAM18 4676501 YP_975671.1 CDS NMC1721 NC_008767.1 1755065 1755937 D oxidoreductase 1755065..1755937 Neisseria meningitidis FAM18 4676502 YP_975672.1 CDS NMC1722 NC_008767.1 1755994 1757196 R hypothetical protein complement(1755994..1757196) Neisseria meningitidis FAM18 4676486 YP_975673.1 CDS NMC1724 NC_008767.1 1757193 1757561 R hypothetical protein complement(1757193..1757561) Neisseria meningitidis FAM18 4676487 YP_975674.1 CDS NMC1725 NC_008767.1 1757735 1758178 D hypothetical protein 1757735..1758178 Neisseria meningitidis FAM18 4676494 YP_975675.1 CDS NMC1726 NC_008767.1 1758305 1759069 R hypothetical protein complement(1758305..1759069) Neisseria meningitidis FAM18 4676495 YP_975676.1 CDS ackA2 NC_008767.1 1759032 1760231 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1759032..1760231) Neisseria meningitidis FAM18 4676469 YP_975677.1 CDS NMC1728 NC_008767.1 1760646 1761815 R hypothetical protein complement(1760646..1761815) Neisseria meningitidis FAM18 4675428 YP_975678.1 CDS acnA NC_008767.1 1762168 1764774 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1762168..1764774) Neisseria meningitidis FAM18 4676470 YP_975679.1 CDS NMC1730 NC_008767.1 1764877 1766094 R hypothetical protein complement(1764877..1766094) Neisseria meningitidis FAM18 4675429 YP_975680.1 CDS ddpX NC_008767.1 1766108 1766833 R D-alanyl-d-alanine dipeptidase complement(1766108..1766833) Neisseria meningitidis FAM18 4676448 YP_975681.1 CDS prpC NC_008767.1 1766923 1768077 R catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase complement(1766923..1768077) Neisseria meningitidis FAM18 4675930 YP_975682.1 CDS prpB NC_008767.1 1768163 1769041 R catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase complement(1768163..1769041) Neisseria meningitidis FAM18 4676027 YP_975683.1 CDS NMC1735 NC_008767.1 1769664 1770974 R permease complement(1769664..1770974) Neisseria meningitidis FAM18 4676053 YP_975684.1 CDS ftsZ NC_008767.1 1771113 1772291 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1771113..1772291) Neisseria meningitidis FAM18 4676449 YP_975685.1 CDS ftsA NC_008767.1 1772410 1773654 R cell division protein complement(1772410..1773654) Neisseria meningitidis FAM18 4676635 YP_975686.1 CDS ftsQ NC_008767.1 1773740 1774468 R cell division protein complement(1773740..1774468) Neisseria meningitidis FAM18 4676608 YP_975687.1 CDS ddl NC_008767.1 1774458 1775372 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase complement(1774458..1775372) Neisseria meningitidis FAM18 4676650 YP_975688.2 CDS murC NC_008767.1 1775485 1776891 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1775485..1776891) Neisseria meningitidis FAM18 4676002 YP_975689.1 CDS murG NC_008767.1 1777048 1778115 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase complement(1777048..1778115) Neisseria meningitidis FAM18 4676263 YP_975690.1 CDS ftsW NC_008767.1 1778119 1779426 R cell division protein complement(1778119..1779426) Neisseria meningitidis FAM18 4676260 YP_975691.1 CDS murD NC_008767.1 1779570 1780907 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(1779570..1780907) Neisseria meningitidis FAM18 4676664 YP_975692.1 CDS NMC1746 NC_008767.1 1780997 1781269 R hypothetical protein complement(1780997..1781269) Neisseria meningitidis FAM18 4676264 YP_975693.1 CDS mraY NC_008767.1 1781384 1782466 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1781384..1782466) Neisseria meningitidis FAM18 4676446 YP_975694.1 CDS NMC1748 NC_008767.1 1782713 1782895 R hypothetical protein complement(1782713..1782895) Neisseria meningitidis FAM18 4676295 YP_975695.1 CDS murF NC_008767.1 1782892 1784331 R deleted EC_number 6.3.2.15; UDP-MurNAc-pentapeptide synthetase complement(1782892..1784331) Neisseria meningitidis FAM18 4676447 YP_975696.1 CDS NMC1750 NC_008767.1 1784374 1786020 R hypothetical protein complement(1784374..1786020) Neisseria meningitidis FAM18 4676085 YP_975697.1 CDS murE NC_008767.1 1786043 1787521 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(1786043..1787521) Neisseria meningitidis FAM18 4676456 YP_975698.1 CDS penA NC_008767.1 1787546 1789291 R penicillin-binding protein 2 complement(1787546..1789291) Neisseria meningitidis FAM18 4676084 YP_975699.1 CDS NMC1754 NC_008767.1 1789352 1789621 R small periplasmic protein complement(1789352..1789621) Neisseria meningitidis FAM18 4676105 YP_975700.1 CDS mraW NC_008767.1 1789612 1790598 R S-adenosyl-methyltransferase MraW complement(1789612..1790598) Neisseria meningitidis FAM18 4676457 YP_975701.1 CDS NMC1756 NC_008767.1 1790595 1791050 R MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ complement(1790595..1791050) Neisseria meningitidis FAM18 4676460 YP_975702.1 CDS NMC1757 NC_008767.1 1791329 1792546 D hypothetical protein 1791329..1792546 Neisseria meningitidis FAM18 4676461 YP_975703.1 CDS NMC1759 NC_008767.1 1793119 1793940 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(1793119..1793940) Neisseria meningitidis FAM18 4676401 YP_975704.1 CDS NMC1760 NC_008767.1 1793973 1794617 R thiol:disulfide interchange protein complement(1793973..1794617) Neisseria meningitidis FAM18 4676402 YP_975705.1 CDS NMC1762 NC_008767.1 1794620 1795471 R hypothetical protein complement(1794620..1795471) Neisseria meningitidis FAM18 4676224 YP_975706.1 CDS NMC1763 NC_008767.1 1795571 1797067 R chelatase complement(1795571..1797067) Neisseria meningitidis FAM18 4676225 YP_975707.1 CDS NMC1764 NC_008767.1 1797081 1797434 R hypothetical protein complement(1797081..1797434) Neisseria meningitidis FAM18 4676413 YP_975708.1 CDS putP NC_008767.1 1797884 1799410 D sodium/proline symporter 1797884..1799410 Neisseria meningitidis FAM18 4676414 YP_975709.1 CDS putA NC_008767.1 1799442 1803264 D proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase join(1799442..1799630,1799629..1803264) Neisseria meningitidis FAM18 4675782 YP_975710.1 CDS NMC1767 NC_008767.1 1804266 1804847 R transposase complement(1804266..1804847) Neisseria meningitidis FAM18 4676030 YP_975711.1 CDS xthA NC_008767.1 1805789 1806559 R exodeoxyribonuclease III complement(1805789..1806559) Neisseria meningitidis FAM18 4676358 YP_975712.1 CDS NMC1769 NC_008767.1 1806619 1806900 R ArsR family transcriptional regulator complement(1806619..1806900) Neisseria meningitidis FAM18 4676667 YP_975713.1 CDS nadC NC_008767.1 1807368 1808249 R nicotinate-nucleotide pyrophosphorylase complement(1807368..1808249) Neisseria meningitidis FAM18 4676359 YP_975714.1 CDS NMC1771 NC_008767.1 1808324 1809262 R cytoplasmic membrane protein complement(1808324..1809262) Neisseria meningitidis FAM18 4676252 YP_975715.1 CDS nadA NC_008767.1 1809569 1810681 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1809569..1810681 Neisseria meningitidis FAM18 4676346 YP_975716.1 CDS nadB NC_008767.1 1810887 1812395 D L-aspartate oxidase 1810887..1812395 Neisseria meningitidis FAM18 4676254 YP_975717.1 CDS NMC1775 NC_008767.1 1813627 1814634 D transposase for IS1106A3 1813627..1814634 Neisseria meningitidis FAM18 4676347 YP_975718.1 CDS pgm2 NC_008767.1 1814844 1815509 R beta-phosphoglucomutase complement(1814844..1815509) Neisseria meningitidis FAM18 4676354 YP_975719.1 CDS mapA NC_008767.1 1815522 1817780 R maltose phosphorylase complement(1815522..1817780) Neisseria meningitidis FAM18 4676132 YP_975720.1 CDS galM NC_008767.1 1818014 1819051 R aldose 1-epimerase complement(1818014..1819051) Neisseria meningitidis FAM18 4676325 YP_975721.1 CDS NMC1779 NC_008767.1 1819055 1820410 R integral membrane transport protein complement(1819055..1820410) Neisseria meningitidis FAM18 4676656 YP_975722.1 CDS NMC1780 NC_008767.1 1820798 1822474 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1820798..1822474 Neisseria meningitidis FAM18 4676355 YP_975723.1 CDS pgpA NC_008767.1 1822534 1823019 R phosphatidylglycerophosphatase A complement(1822534..1823019) Neisseria meningitidis FAM18 4676352 YP_975724.1 CDS thiL NC_008767.1 1823012 1823968 R catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase complement(1823012..1823968) Neisseria meningitidis FAM18 4676040 YP_975725.1 CDS rmpM NC_008767.1 1824789 1825517 R outer membrane protein class 4 complement(1824789..1825517) Neisseria meningitidis FAM18 4675200 YP_975726.1 CDS NMC1784 NC_008767.1 1825881 1826831 D transcriptional regulator CysB-like protein 1825881..1826831 Neisseria meningitidis FAM18 4675578 YP_975727.1 CDS NMC1785 NC_008767.1 1826944 1827678 R anaerobic transcriptional regulatory protein complement(1826944..1827678) Neisseria meningitidis FAM18 4676353 YP_975728.1 CDS hemN NC_008767.1 1827883 1829304 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1827883..1829304 Neisseria meningitidis FAM18 4675664 YP_975729.1 CDS NMC1787 NC_008767.1 1829657 1831231 R phosphate permease complement(1829657..1831231) Neisseria meningitidis FAM18 4676498 YP_975730.1 CDS anmK NC_008767.1 1831553 1832656 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1831553..1832656 Neisseria meningitidis FAM18 4675665 YP_975731.1 CDS mafA2 NC_008767.1 1832775 1833716 D adhesin 1832775..1833716 Neisseria meningitidis FAM18 4676322 YP_975732.1 CDS NMC1790 NC_008767.1 1833720 1835483 D adhesin 1833720..1835483 Neisseria meningitidis FAM18 4676327 YP_975733.1 CDS NMC1791 NC_008767.1 1835486 1835809 D LOW G+C REGION; hypothetical protein 1835486..1835809 Neisseria meningitidis FAM18 4676323 YP_975734.1 CDS NMC1792 NC_008767.1 1835862 1836095 D LOW G+C REGION; hypothetical protein 1835862..1836095 Neisseria meningitidis FAM18 4676320 YP_975735.1 CDS NMC1793 NC_008767.1 1836222 1836764 D LOW G+C REGION; hypothetical protein 1836222..1836764 Neisseria meningitidis FAM18 4676321 YP_975736.1 CDS NMC1795 NC_008767.1 1837582 1837980 D hypothetical protein 1837582..1837980 Neisseria meningitidis FAM18 4676341 YP_975737.1 CDS NMC1796 NC_008767.1 1838011 1838388 D hypothetical protein 1838011..1838388 Neisseria meningitidis FAM18 4676303 YP_975738.1 CDS NMC1797 NC_008767.1 1838520 1838984 D hypothetical protein 1838520..1838984 Neisseria meningitidis FAM18 4676304 YP_975739.1 CDS NMC1798 NC_008767.1 1838993 1839265 D hypothetical protein 1838993..1839265 Neisseria meningitidis FAM18 4676281 YP_975740.1 CDS NMC1799 NC_008767.1 1839432 1839662 D hypothetical protein 1839432..1839662 Neisseria meningitidis FAM18 4676282 YP_975741.1 CDS NMC1800 NC_008767.1 1839813 1840442 D hypothetical protein 1839813..1840442 Neisseria meningitidis FAM18 4676279 YP_975742.1 CDS NMC1801 NC_008767.1 1840393 1840878 D hypothetical protein 1840393..1840878 Neisseria meningitidis FAM18 4676280 YP_975743.1 CDS NMC1802 NC_008767.1 1841099 1841458 D LOW G+C REGION; lipoprotein 1841099..1841458 Neisseria meningitidis FAM18 4676297 YP_975744.1 CDS NMC1803 NC_008767.1 1841470 1841805 D hypothetical protein 1841470..1841805 Neisseria meningitidis FAM18 4676298 YP_975745.1 CDS NMC1804 NC_008767.1 1842109 1843233 D hypothetical protein 1842109..1843233 Neisseria meningitidis FAM18 4676311 YP_975746.1 CDS NMC1805 NC_008767.1 1843320 1843595 R hypothetical protein complement(1843320..1843595) Neisseria meningitidis FAM18 4676312 YP_975747.1 CDS NMC1806 NC_008767.1 1843612 1844379 R hypothetical protein complement(1843612..1844379) Neisseria meningitidis FAM18 4676248 YP_975748.1 CDS NMC1807 NC_008767.1 1844804 1845079 R hypothetical protein complement(1844804..1845079) Neisseria meningitidis FAM18 4676249 YP_975749.1 CDS NMC1808 NC_008767.1 1845076 1846359 R integral membrane signal transducer protein complement(1845076..1846359) Neisseria meningitidis FAM18 4676276 YP_975750.1 CDS glnA NC_008767.1 1846513 1847931 R glutamine synthetase complement(1846513..1847931) Neisseria meningitidis FAM18 4676277 YP_975751.1 CDS aroE NC_008767.1 1848753 1849562 D shikimate dehydrogenase 1848753..1849562 Neisseria meningitidis FAM18 4676581 YP_975752.1 CDS mtgA NC_008767.1 1849564 1850265 D glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 1849564..1850265 Neisseria meningitidis FAM18 4675566 YP_975753.1 CDS NMC1812 NC_008767.1 1850734 1851498 R ABC transporter ATP-binding protein complement(1850734..1851498) Neisseria meningitidis FAM18 4676296 YP_975754.1 CDS NMC1813 NC_008767.1 1851542 1852072 R hypothetical protein complement(1851542..1852072) Neisseria meningitidis FAM18 4676241 YP_975755.1 CDS NMC1814 NC_008767.1 1852053 1852634 R hypothetical protein complement(1852053..1852634) Neisseria meningitidis FAM18 4676242 YP_975756.1 CDS NMC1815 NC_008767.1 1852631 1853167 R hypothetical protein complement(1852631..1853167) Neisseria meningitidis FAM18 4676057 YP_975757.1 CDS NMC1816 NC_008767.1 1853232 1854206 R hypothetical protein complement(1853232..1854206) Neisseria meningitidis FAM18 4676058 YP_975758.1 CDS tal NC_008767.1 1854303 1855358 D catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 1854303..1855358 Neisseria meningitidis FAM18 4676049 YP_975759.1 CDS NMC1819 NC_008767.1 1855512 1855802 D hypothetical protein 1855512..1855802 Neisseria meningitidis FAM18 4674943 YP_975760.1 CDS NMC1820 NC_008767.1 1855819 1856706 D this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 1855819..1856706 Neisseria meningitidis FAM18 4676050 YP_975761.1 CDS NMC1822 NC_008767.1 1856776 1857786 R tRNA-dihydrouridine synthase A complement(1856776..1857786) Neisseria meningitidis FAM18 4676197 YP_975762.1 CDS NMC1823 NC_008767.1 1857817 1858308 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1857817..1858308) Neisseria meningitidis FAM18 4676198 YP_975763.1 CDS NMC1824 NC_008767.1 1858382 1859101 R hypothetical protein complement(1858382..1859101) Neisseria meningitidis FAM18 4676184 YP_975764.1 CDS NMC1825 NC_008767.1 1859211 1860077 R hypothetical protein complement(1859211..1860077) Neisseria meningitidis FAM18 4676185 YP_975765.1 CDS NMC1826 NC_008767.1 1860126 1860404 R hypothetical protein complement(1860126..1860404) Neisseria meningitidis FAM18 4675935 YP_975766.2 CDS NMC1827 NC_008767.1 1860404 1860694 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein complement(1860404..1860694) Neisseria meningitidis FAM18 4675936 YP_975767.1 CDS NMC1828 NC_008767.1 1860697 1861245 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1860697..1861245) Neisseria meningitidis FAM18 4676017 YP_975768.1 CDS tspA NC_008767.1 1861433 1864060 D hypothetical protein 1861433..1864060 Neisseria meningitidis FAM18 4676018 YP_975769.1 CDS gloA NC_008767.1 1864232 1864648 R lactoylglutathione lyase complement(1864232..1864648) Neisseria meningitidis FAM18 4674755 YP_975770.1 CDS NMC1831 NC_008767.1 1864695 1865864 R tetratricopeptide repeat protein complement(1864695..1865864) Neisseria meningitidis FAM18 4676604 YP_975771.1 CDS NMC1832 NC_008767.1 1865875 1866231 R hypothetical protein complement(1865875..1866231) Neisseria meningitidis FAM18 4676160 YP_975772.1 CDS ilvE NC_008767.1 1866499 1867497 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1866499..1867497 Neisseria meningitidis FAM18 4676161 YP_975773.1 CDS fabI NC_008767.1 1867683 1868468 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(1867683..1868468) Neisseria meningitidis FAM18 4676438 YP_975774.1 CDS dapD NC_008767.1 1868623 1869444 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(1868623..1869444) Neisseria meningitidis FAM18 4675841 YP_975775.1 CDS pgi NC_008767.1 1869654 1871408 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1869654..1871408) Neisseria meningitidis FAM18 4675961 YP_975776.1 CDS pilG NC_008767.1 1871807 1873039 D pilus-assembly protein 1871807..1873039 Neisseria meningitidis FAM18 4676142 YP_975777.1 CDS pilD NC_008767.1 1873113 1873973 D type IV prepilin leader peptidase 1873113..1873973 Neisseria meningitidis FAM18 4676109 YP_975778.1 CDS NMC1841 NC_008767.1 1873975 1874607 D hypothetical protein 1873975..1874607 Neisseria meningitidis FAM18 4676104 YP_975779.1 CDS NMC1842 NC_008767.1 1874600 1874809 D hypothetical protein 1874600..1874809 Neisseria meningitidis FAM18 4676177 YP_975780.1 CDS pilF NC_008767.1 1874894 1876570 R type IV pilus assembly protein complement(1874894..1876570) Neisseria meningitidis FAM18 4676178 YP_975781.1 CDS NMC1845 NC_008767.1 1877062 1877508 R hypothetical protein complement(1877062..1877508) Neisseria meningitidis FAM18 4675956 YP_975782.1 CDS NMC1846 NC_008767.1 1877513 1878487 R octaprenyl-diphosphate synthase complement(1877513..1878487) Neisseria meningitidis FAM18 4675981 YP_975783.1 CDS rplU NC_008767.1 1878711 1879019 D 50S ribosomal protein L21 1878711..1879019 Neisseria meningitidis FAM18 4675982 YP_975784.1 CDS rpmA NC_008767.1 1879044 1879316 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1879044..1879316 Neisseria meningitidis FAM18 4675373 YP_975785.1 CDS NMC1849 NC_008767.1 1879350 1880735 D hypothetical protein 1879350..1880735 Neisseria meningitidis FAM18 4675440 YP_975786.1 CDS rpmG NC_008767.1 1881006 1881161 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1881006..1881161) Neisseria meningitidis FAM18 4676158 YP_975787.1 CDS rpmB NC_008767.1 1881193 1881426 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1881193..1881426) Neisseria meningitidis FAM18 4675294 YP_975788.1 CDS emrB NC_008767.1 1881676 1883226 R multidrug resistance translocase complement(1881676..1883226) Neisseria meningitidis FAM18 4675437 YP_975789.1 CDS emrA NC_008767.1 1883226 1884482 R multidrug resistance translocase complement(1883226..1884482) Neisseria meningitidis FAM18 4675899 YP_975790.1 CDS NMC1854 NC_008767.1 1884675 1885148 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1884675..1885148 Neisseria meningitidis FAM18 4675922 YP_975791.1 CDS NMC1855 NC_008767.1 1885223 1885909 D hypothetical protein 1885223..1885909 Neisseria meningitidis FAM18 4676159 YP_975792.1 CDS NMC1856 NC_008767.1 1886412 1887704 R hypothetical protein complement(1886412..1887704) Neisseria meningitidis FAM18 4676148 YP_975793.1 CDS NMC1857 NC_008767.1 1887781 1888749 D hypothetical protein 1887781..1888749 Neisseria meningitidis FAM18 4676149 YP_975794.1 CDS NMC1858 NC_008767.1 1888950 1890419 R hypothetical protein complement(1888950..1890419) Neisseria meningitidis FAM18 4676154 YP_975795.1 CDS NMC1861 NC_008767.1 1893555 1894763 D replication initiation factor 1893555..1894763 Neisseria meningitidis FAM18 4676706 YP_975796.1 CDS NMC1862 NC_008767.1 1894784 1895095 D hypothetical protein 1894784..1895095 Neisseria meningitidis FAM18 4676162 YP_975797.1 CDS NMC1863 NC_008767.1 1895099 1895299 D hypothetical protein 1895099..1895299 Neisseria meningitidis FAM18 4676163 YP_975798.1 CDS NMC1864 NC_008767.1 1895537 1895767 D hypothetical protein 1895537..1895767 Neisseria meningitidis FAM18 4676113 YP_975799.1 CDS NMC1865 NC_008767.1 1895796 1896098 D hypothetical protein 1895796..1896098 Neisseria meningitidis FAM18 4676114 YP_975800.1 CDS NMC1866 NC_008767.1 1896545 1898050 D TspB protein 1896545..1898050 Neisseria meningitidis FAM18 4676025 YP_975801.1 CDS NMC1867 NC_008767.1 1898353 1898637 D hypothetical protein 1898353..1898637 Neisseria meningitidis FAM18 4676026 YP_975802.1 CDS NMC1868 NC_008767.1 1898638 1899825 D hypothetical protein 1898638..1899825 Neisseria meningitidis FAM18 4676004 YP_975803.1 CDS NMC1869 NC_008767.1 1900040 1900996 D invertase/transposase 1900040..1900996 Neisseria meningitidis FAM18 4676005 YP_975804.1 CDS NMC1870 NC_008767.1 1902080 1902325 R hypothetical protein complement(1902080..1902325) Neisseria meningitidis FAM18 4676037 YP_975805.1 CDS NMC1871 NC_008767.1 1902428 1902865 D hypothetical protein 1902428..1902865 Neisseria meningitidis FAM18 4676038 YP_975806.1 CDS NMC1872 NC_008767.1 1902862 1903353 D hypothetical protein 1902862..1903353 Neisseria meningitidis FAM18 4675906 YP_975807.1 CDS folA NC_008767.1 1903703 1904191 R dihydrofolate reductase complement(1903703..1904191) Neisseria meningitidis FAM18 4675907 YP_975808.1 CDS aroG NC_008767.1 1904259 1905314 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1904259..1905314) Neisseria meningitidis FAM18 4676702 YP_975809.1 CDS NMC1875 NC_008767.1 1905368 1905661 D hypothetical protein 1905368..1905661 Neisseria meningitidis FAM18 4675567 YP_975810.1 CDS NMC1876 NC_008767.1 1905779 1905871 D hypothetical protein 1905779..1905871 Neisseria meningitidis FAM18 4676129 YP_975811.1 CDS opcB NC_008767.1 1905960 1906238 D hypothetical protein 1905960..1906238 Neisseria meningitidis FAM18 4676130 YP_975812.1 CDS NMC1879 NC_008767.1 1906495 1906941 R hypothetical protein complement(1906495..1906941) Neisseria meningitidis FAM18 4676082 YP_975813.1 CDS NMC1880 NC_008767.1 1907066 1907530 R DNA transport competence protein complement(1907066..1907530) Neisseria meningitidis FAM18 4676083 YP_975814.1 CDS NMC1882 NC_008767.1 1913331 1914137 R hypothetical protein complement(1913331..1914137) Neisseria meningitidis FAM18 4676116 YP_975815.1 CDS ffh NC_008767.1 1914357 1915727 D signal recognition particle protein 1914357..1915727 Neisseria meningitidis FAM18 4676117 YP_975816.1 CDS NMC1884 NC_008767.1 1916101 1917066 D transposase for IS1655 1916101..1917066 Neisseria meningitidis FAM18 4676590 YP_975817.1 CDS NMC1885 NC_008767.1 1917143 1917838 R thiol:disulfide interchange protein complement(1917143..1917838) Neisseria meningitidis FAM18 4675941 YP_975818.1 CDS NMC1886 NC_008767.1 1918009 1918668 R hypothetical protein complement(1918009..1918668) Neisseria meningitidis FAM18 4675942 YP_975819.1 CDS NMC1887 NC_008767.1 1918871 1920982 R TonB-dependent receptor protein complement(1918871..1920982) Neisseria meningitidis FAM18 4676047 YP_975820.1 CDS NMC1889 NC_008767.1 1921168 1921773 R hypothetical protein complement(1921168..1921773) Neisseria meningitidis FAM18 4676048 YP_975821.1 CDS NMC1890 NC_008767.1 1921822 1922283 R hypothetical protein complement(1921822..1922283) Neisseria meningitidis FAM18 4676090 YP_975822.1 CDS NMC1891 NC_008767.1 1922328 1923239 D LysR family transcriptional regulator 1922328..1923239 Neisseria meningitidis FAM18 4676091 YP_975823.1 CDS phr NC_008767.1 1923229 1924530 D deoxyribodopyrimidine photolyase 1923229..1924530 Neisseria meningitidis FAM18 4676086 YP_975824.1 CDS NMC1894 NC_008767.1 1924635 1925219 D IS1106 transposase (fragment) 1924635..1925219 Neisseria meningitidis FAM18 4676118 YP_975825.1 CDS NMC1896 NC_008767.1 1925685 1925960 D hypothetical protein 1925685..1925960 Neisseria meningitidis FAM18 4676087 YP_975826.1 CDS NMC1898 NC_008767.1 1926177 1926971 R hypothetical protein complement(1926177..1926971) Neisseria meningitidis FAM18 4676072 YP_975827.1 CDS NMC1899 NC_008767.1 1927180 1927905 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1927180..1927905 Neisseria meningitidis FAM18 4676073 YP_975828.1 CDS lgtB2 NC_008767.1 1930082 1930888 R lacto-N-neotetraose biosynthesis glycosyl transferase complement(1930082..1930888) Neisseria meningitidis FAM18 4676045 YP_975829.1 CDS NMC1900A NC_008767.1 1930930 1931025 R hypothetical protein complement(1930930..1931025) Neisseria meningitidis FAM18 4675979 YP_975830.1 CDS lgtB NC_008767.1 1931037 1931864 R lacto-N-neotetraose biosynthesis glycosyl transferase complement(1931037..1931864) Neisseria meningitidis FAM18 4676046 YP_975831.1 CDS lgtA NC_008767.1 1931906 1932952 R lacto-N-neotetraose biosynthesis glycosyl transferase complement(1931906..1932952) Neisseria meningitidis FAM18 4675978 YP_975832.1 CDS glyS NC_008767.1 1932969 1935032 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1932969..1935032) Neisseria meningitidis FAM18 4676390 YP_975833.1 CDS glyQ NC_008767.1 1935149 1936045 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1935149..1936045) Neisseria meningitidis FAM18 4676553 YP_975834.1 CDS atpC NC_008767.1 1936369 1936791 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(1936369..1936791) Neisseria meningitidis FAM18 4676552 YP_975835.1 CDS atpD NC_008767.1 1936802 1938199 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(1936802..1938199) Neisseria meningitidis FAM18 4676545 YP_975836.1 CDS atpG NC_008767.1 1938237 1939112 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(1938237..1939112) Neisseria meningitidis FAM18 4676546 YP_975837.1 CDS atpA NC_008767.1 1939137 1940684 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(1939137..1940684) Neisseria meningitidis FAM18 4675645 YP_975838.1 CDS atpH NC_008767.1 1940695 1941228 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(1940695..1941228) Neisseria meningitidis FAM18 4675633 YP_975839.1 CDS atpF NC_008767.1 1941233 1941703 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(1941233..1941703) Neisseria meningitidis FAM18 4675646 YP_975840.1 CDS atpE NC_008767.1 1941774 1942010 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(1941774..1942010) Neisseria meningitidis FAM18 4675670 YP_975841.1 CDS atpB NC_008767.1 1942067 1942933 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(1942067..1942933) Neisseria meningitidis FAM18 4675669 YP_975842.1 CDS atpI NC_008767.1 1942923 1943276 R ATP synthase I complement(1942923..1943276) Neisseria meningitidis FAM18 4675634 YP_975843.1 CDS NMC1914 NC_008767.1 1943644 1943982 R hypothetical protein complement(1943644..1943982) Neisseria meningitidis FAM18 4676675 YP_975844.1 CDS NMC1915 NC_008767.1 1944117 1944977 R chromosome segregation proteins complement(1944117..1944977) Neisseria meningitidis FAM18 4676076 YP_975845.1 CDS NMC1916 NC_008767.1 1945033 1945704 D aromatic acid decarboxylase 1945033..1945704 Neisseria meningitidis FAM18 4676077 YP_975846.1 CDS NMC1917 NC_008767.1 1945766 1946629 R lipoprotein complement(1945766..1946629) Neisseria meningitidis FAM18 4675988 YP_975847.1 CDS NMC1918 NC_008767.1 1946788 1947474 R inner membrane transport protein complement(1946788..1947474) Neisseria meningitidis FAM18 4675989 YP_975848.1 CDS NMC1919 NC_008767.1 1947477 1948214 R ABC transport ATP-binding subunit complement(1947477..1948214) Neisseria meningitidis FAM18 4675849 YP_975849.1 CDS NMC1920 NC_008767.1 1948745 1950592 D transglycosylase 1948745..1950592 Neisseria meningitidis FAM18 4675850 YP_975850.1 CDS rpsU NC_008767.1 1950881 1951093 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1950881..1951093 Neisseria meningitidis FAM18 4676070 YP_975851.1 CDS NMC1922 NC_008767.1 1951267 1951671 D hypothetical protein 1951267..1951671 Neisseria meningitidis FAM18 4675123 YP_975852.1 CDS regG NC_008767.1 1951996 1952451 R ClpXP protease specificity-enhancing factor complement(1951996..1952451) Neisseria meningitidis FAM18 4676071 YP_975853.1 CDS regF NC_008767.1 1952459 1953064 R regulator of pilE expression complement(1952459..1953064) Neisseria meningitidis FAM18 4675746 YP_975854.1 CDS NMC1926 NC_008767.1 1953334 1955046 R hypothetical protein complement(1953334..1955046) Neisseria meningitidis FAM18 4675672 YP_975855.1 CDS NMC1927 NC_008767.1 1955151 1955792 R cadmium resistance protein complement(1955151..1955792) Neisseria meningitidis FAM18 4676061 YP_975856.2 CDS rpmE NC_008767.1 1956095 1956310 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(1956095..1956310) Neisseria meningitidis FAM18 4676062 YP_975857.1 CDS NMC1929 NC_008767.1 1956545 1957062 D acetyltransferase join(1956545..1956856,1956856..1957062) Neisseria meningitidis FAM18 4675434 YP_975858.1 CDS NMC1930 NC_008767.1 1957146 1957634 R hypothetical protein complement(1957146..1957634) Neisseria meningitidis FAM18 4676059 YP_975859.1 CDS NMC1931 NC_008767.1 1957631 1958014 R hypothetical protein complement(1957631..1958014) Neisseria meningitidis FAM18 4676060 YP_975860.1 CDS NMC1932 NC_008767.1 1958014 1958496 R hypothetical protein complement(1958014..1958496) Neisseria meningitidis FAM18 4676042 YP_975861.1 CDS NMC1933 NC_008767.1 1958501 1959328 R periplasmic/outer membrane protein complement(1958501..1959328) Neisseria meningitidis FAM18 4676043 YP_975862.1 CDS NMC1934 NC_008767.1 1959325 1959627 R hypothetical protein complement(1959325..1959627) Neisseria meningitidis FAM18 4676012 YP_975863.1 CDS NMC1935 NC_008767.1 1959660 1960250 R periplasmic transport protein complement(1959660..1960250) Neisseria meningitidis FAM18 4676013 YP_975864.1 CDS NMC1936 NC_008767.1 1960287 1960766 R outer membrane transport protein complement(1960287..1960766) Neisseria meningitidis FAM18 4675997 YP_975865.1 CDS NMC1937 NC_008767.1 1960832 1961608 R ABC transport inner membrane subunit complement(1960832..1961608) Neisseria meningitidis FAM18 4675998 YP_975866.1 CDS NMC1938 NC_008767.1 1961657 1962517 R ABC transport ATP-binding protein complement(1961657..1962517) Neisseria meningitidis FAM18 4676033 YP_975867.1 CDS NMC1939 NC_008767.1 1962630 1963543 D transcriptional regulator join(1962630..1963049,1963053..1963289,1963285..1963449,1963451..1963543) Neisseria meningitidis FAM18 4676034 YP_975868.1 CDS NMC1940 NC_008767.1 1963751 1964140 D hypothetical protein 1963751..1964140 Neisseria meningitidis FAM18 4675986 YP_975869.1 CDS NMC1941 NC_008767.1 1964149 1964349 D hypothetical protein 1964149..1964349 Neisseria meningitidis FAM18 4675987 YP_975870.1 CDS aldA NC_008767.1 1964384 1965826 D NAD-linked; aldehyde dehydrogenase 1964384..1965826 Neisseria meningitidis FAM18 4675715 YP_975871.1 CDS NMC1943 NC_008767.1 1967026 1970228 D outer membrane peptidase join(1967026..1967313,1967313..1970228) Neisseria meningitidis FAM18 4676385 YP_975872.1 CDS NMC1944 NC_008767.1 1971412 1973208 D para-aminobenzoate synthase component I 1971412..1973208 Neisseria meningitidis FAM18 4675716 YP_975873.1 CDS NMC1945 NC_008767.1 1973267 1974784 R hypothetical protein complement(1973267..1974784) Neisseria meningitidis FAM18 4675713 YP_975874.1 CDS hpuA NC_008767.1 1975529 1976554 D hemoglobin-haptoglobin-utilization protein 1975529..1976554 Neisseria meningitidis FAM18 4675714 YP_975875.1 CDS hpuB NC_008767.1 1976585 1979017 D hemoglobin-haptoglobin-utilization protein 1976585..1979017 Neisseria meningitidis FAM18 4676377 YP_975876.1 CDS groEL NC_008767.1 1979605 1981239 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL complement(1979605..1981239) Neisseria meningitidis FAM18 4676463 YP_975877.1 CDS groES NC_008767.1 1981332 1981658 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(1981332..1981658) Neisseria meningitidis FAM18 4676481 YP_975878.1 CDS NMC1950 NC_008767.1 1981852 1982505 D insertion element IS1016 transposase 1981852..1982505 Neisseria meningitidis FAM18 4676250 YP_975879.1 CDS NMC1951 NC_008767.1 1982622 1984253 D sodium-dependent inner membrane transport protein 1982622..1984253 Neisseria meningitidis FAM18 4675710 YP_975880.1 CDS lysA NC_008767.1 1984378 1985622 R diaminopimelate decarboxylase complement(1984378..1985622) Neisseria meningitidis FAM18 4675711 YP_975881.1 CDS NMC1953 NC_008767.1 1985633 1985803 R lipoprotein complement(1985633..1985803) Neisseria meningitidis FAM18 4676339 YP_975882.1 CDS cyaY NC_008767.1 1985874 1986197 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 1985874..1986197 Neisseria meningitidis FAM18 4675707 YP_975883.1 CDS NMC1955 NC_008767.1 1986228 1986647 D hypothetical protein 1986228..1986647 Neisseria meningitidis FAM18 4675708 YP_975884.1 CDS NMC1956 NC_008767.1 1986669 1987175 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1986669..1987175 Neisseria meningitidis FAM18 4676172 YP_975885.1 CDS polA NC_008767.1 1987321 1990113 D DNA polymerase I 1987321..1990113 Neisseria meningitidis FAM18 4676173 YP_975886.1 CDS NMC1958 NC_008767.1 1991459 1992181 D hypothetical protein 1991459..1992181 Neisseria meningitidis FAM18 4676092 YP_975887.1 CDS iga2 NC_008767.1 1992290 1996654 R IgA-specific serine endopeptidase complement(1992290..1996654) Neisseria meningitidis FAM18 4674929 YP_975888.1 CDS NMC1960 NC_008767.1 1996788 1997219 R hypothetical protein complement(1996788..1997219) Neisseria meningitidis FAM18 4676439 YP_975889.1 CDS NMC1961 NC_008767.1 1997216 1997371 R hypothetical protein complement(1997216..1997371) Neisseria meningitidis FAM18 4674930 YP_975890.1 CDS trmE NC_008767.1 1997502 1998848 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1997502..1998848 Neisseria meningitidis FAM18 4674878 YP_975891.1 CDS fetA NC_008767.1 2000909 2003053 D iron-regulated outer membrane protein 2000909..2003053 Neisseria meningitidis FAM18 4675204 YP_975892.1 CDS fetB NC_008767.1 2003309 2004322 D membrane transport solute-binding protein 2003309..2004322 Neisseria meningitidis FAM18 4675149 YP_975893.1 CDS NMC1965 NC_008767.1 2004789 2005622 D inner membrane transport protein 2004789..2005622 Neisseria meningitidis FAM18 4675150 YP_975894.1 CDS NMC1966 NC_008767.1 2005612 2006586 D inner membrane transport protein 2005612..2006586 Neisseria meningitidis FAM18 4674879 YP_975895.1 CDS NMC1967 NC_008767.1 2006631 2007257 D hypothetical protein 2006631..2007257 Neisseria meningitidis FAM18 4675157 YP_975896.1 CDS NMC1968 NC_008767.1 2007342 2008100 D ABC transporter ATP-binding subunit 2007342..2008100 Neisseria meningitidis FAM18 4675158 YP_975897.1 CDS NMC1969 NC_008767.1 2008404 2009600 D adhesin/invasin 2008404..2009600 Neisseria meningitidis FAM18 4675703 YP_975898.1 CDS glnB NC_008767.1 2009666 2010004 R nitrogen regulatory protein P-II 1 complement(2009666..2010004) Neisseria meningitidis FAM18 4675704 YP_975899.1 CDS purL NC_008767.1 2010140 2014117 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2010140..2014117 Neisseria meningitidis FAM18 4676582 YP_975900.1 CDS NMC1973 NC_008767.1 2014212 2014970 D hydroxyacylglutathione hydrolase 2014212..2014970 Neisseria meningitidis FAM18 4675794 YP_975901.1 CDS NMC1976 NC_008767.1 2019991 2021445 D hypothetical protein 2019991..2021445 Neisseria meningitidis FAM18 4675702 YP_975902.1 CDS hslO NC_008767.1 2021531 2022532 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 complement(2021531..2022532) Neisseria meningitidis FAM18 4674817 YP_975903.1 CDS NMC1978 NC_008767.1 2022684 2023439 D hypothetical protein 2022684..2023439 Neisseria meningitidis FAM18 4674818 YP_975904.1 CDS NMC1979 NC_008767.1 2023458 2023676 D hypothetical protein 2023458..2023676 Neisseria meningitidis FAM18 4674820 YP_975905.1 CDS NMC1980 NC_008767.1 2023821 2024165 D hypothetical protein 2023821..2024165 Neisseria meningitidis FAM18 4674821 YP_975906.1 CDS NMC1981 NC_008767.1 2024165 2024857 D hypothetical protein 2024165..2024857 Neisseria meningitidis FAM18 4675268 YP_975907.1 CDS argJ NC_008767.1 2024924 2026144 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 2024924..2026144 Neisseria meningitidis FAM18 4675269 YP_975908.1 CDS NMC1983 NC_008767.1 2026291 2027613 D hypothetical protein 2026291..2027613 Neisseria meningitidis FAM18 4676239 YP_975909.1 CDS NMC1984 NC_008767.1 2027802 2029193 D ATP-dependent DNA helicase 2027802..2029193 Neisseria meningitidis FAM18 4674880 YP_975910.1 CDS NMC1985 NC_008767.1 2029294 2030421 D hypothetical protein 2029294..2030421 Neisseria meningitidis FAM18 4674881 YP_975911.1 CDS NMC1986 NC_008767.1 2030602 2032176 D hypothetical protein 2030602..2032176 Neisseria meningitidis FAM18 4674797 YP_975912.1 CDS NMC1987 NC_008767.1 2032242 2035541 D DNA helicase 2032242..2035541 Neisseria meningitidis FAM18 4674798 YP_975913.1 CDS vsr NC_008767.1 2035564 2035950 R patch repair protein complement(2035564..2035950) Neisseria meningitidis FAM18 4674782 YP_975914.1 CDS NMC1991 NC_008767.1 2035990 2037672 R hypothetical protein complement(2035990..2037672) Neisseria meningitidis FAM18 4676537 YP_975915.1 CDS NMC1992 NC_008767.1 2037650 2038705 R deleted EC_number 2.1.1.73; cytosine-specific DNA methylase complement(2037650..2038705) Neisseria meningitidis FAM18 4674783 YP_975916.1 CDS NMC1993 NC_008767.1 2039326 2040291 D insertion element IS1655 transposase 2039326..2040291 Neisseria meningitidis FAM18 4675258 YP_975917.1 CDS NMC1994 NC_008767.1 2040934 2041203 D hypothetical protein 2040934..2041203 Neisseria meningitidis FAM18 4675259 YP_975918.1 CDS NMC1995 NC_008767.1 2041364 2041813 R pilin complement(2041364..2041813) Neisseria meningitidis FAM18 4676450 YP_975919.1 CDS NMC1996 NC_008767.1 2041901 2042365 R DNA transport competence protein complement(2041901..2042365) Neisseria meningitidis FAM18 4676451 YP_975920.1 CDS NMC1997 NC_008767.1 2048049 2048759 R psedouridine synthase complement(2048049..2048759) Neisseria meningitidis FAM18 4674925 YP_975921.1 CDS coaD NC_008767.1 2048734 2049246 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(2048734..2049246) Neisseria meningitidis FAM18 4674926 YP_975922.1 CDS NMC1999 NC_008767.1 2049370 2050053 R hypothetical protein complement(2049370..2050053) Neisseria meningitidis FAM18 4676419 YP_975923.1 CDS NMC2000 NC_008767.1 2050210 2050476 R hypothetical protein complement(2050210..2050476) Neisseria meningitidis FAM18 4675647 YP_975924.1 CDS NMC2001 NC_008767.1 2050551 2051021 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2050551..2051021) Neisseria meningitidis FAM18 4675648 YP_975925.1 CDS NMC2002 NC_008767.1 2051075 2051461 R hypothetical protein complement(2051075..2051461) Neisseria meningitidis FAM18 4676631 YP_975926.1 CDS NMC2003 NC_008767.1 2051520 2052125 R hypothetical protein complement(2051520..2052125) Neisseria meningitidis FAM18 4676632 YP_975927.1 CDS NMC2004 NC_008767.1 2052122 2052721 R hypothetical protein complement(2052122..2052721) Neisseria meningitidis FAM18 4675291 YP_975928.1 CDS NMC2005 NC_008767.1 2052750 2054342 R permease complement(2052750..2054342) Neisseria meningitidis FAM18 4675292 YP_975929.1 CDS gntP NC_008767.1 2054682 2056067 D gluconate permease 2054682..2056067 Neisseria meningitidis FAM18 4675691 YP_975930.1 CDS NMC2007 NC_008767.1 2056087 2056605 D glucokinase 2056087..2056605 Neisseria meningitidis FAM18 4675983 YP_975931.1 CDS thrB NC_008767.1 2056944 2057861 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase complement(2056944..2057861) Neisseria meningitidis FAM18 4675692 YP_975932.1 CDS ubiG NC_008767.1 2057898 2058647 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(2057898..2058647) Neisseria meningitidis FAM18 4675197 YP_975933.1 CDS NMC2010 NC_008767.1 2058778 2060019 D amino-acid transport protein 2058778..2060019 Neisseria meningitidis FAM18 4676474 YP_975934.1 CDS NMC2011 NC_008767.1 2060077 2061135 D protein LgtG 2060077..2061135 Neisseria meningitidis FAM18 4675685 YP_975935.1 CDS NMC2012 NC_008767.1 2061202 2062854 R hypothetical protein complement(2061202..2062854) Neisseria meningitidis FAM18 4675686 YP_975936.1 CDS NMC2013 NC_008767.1 2063024 2063595 D hypothetical protein join(2063024..2063266,2063266..2063595) Neisseria meningitidis FAM18 4675697 YP_975937.1 CDS NMC2014 NC_008767.1 2063592 2064155 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 2063592..2064155 Neisseria meningitidis FAM18 4675698 YP_975938.1 CDS nlaB NC_008767.1 2064185 2064928 D 1-acyl-SN-glycerol-3-phosphate acyltransferase 2064185..2064928 Neisseria meningitidis FAM18 4675393 YP_975939.1 CDS NMC2016 NC_008767.1 2064925 2065617 D hypothetical protein 2064925..2065617 Neisseria meningitidis FAM18 4676226 YP_975940.1 CDS truA NC_008767.1 2067123 2067920 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2067123..2067920 Neisseria meningitidis FAM18 4675394 YP_975941.1 CDS NMC2018 NC_008767.1 2068043 2068282 D hypothetical protein 2068043..2068282 Neisseria meningitidis FAM18 4675185 YP_975942.1 CDS chpA NC_008767.1 2068270 2068593 D PEMK-like protein 2068270..2068593 Neisseria meningitidis FAM18 4676692 YP_975943.1 CDS porB NC_008767.1 2069294 2070508 D porin 2069294..2070508 Neisseria meningitidis FAM18 4676662 YP_975944.1 CDS thiC NC_008767.1 2072542 2074443 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(2072542..2074443) Neisseria meningitidis FAM18 4676064 YP_975945.1 CDS NMC2022 NC_008767.1 2075041 2075916 D hypothetical protein 2075041..2075916 Neisseria meningitidis FAM18 4674912 YP_975946.1 CDS NMC2023 NC_008767.1 2075925 2076863 D ABC transporter ATP-binding protein 2075925..2076863 Neisseria meningitidis FAM18 4676693 YP_975947.1 CDS ptsI NC_008767.1 2078138 2079913 R phosphoenolpyruvate-protein phosphotransferase complement(2078138..2079913) Neisseria meningitidis FAM18 4676530 YP_975948.1 CDS ptsH NC_008767.1 2079913 2080182 R sugar transport PTS system phosphocarrier protein HPr complement(2079913..2080182) Neisseria meningitidis FAM18 4676011 YP_975949.1 CDS NMC2026 NC_008767.1 2080251 2080688 R sugar transport PTS system IIA component complement(2080251..2080688) Neisseria meningitidis FAM18 4676010 YP_975950.1 CDS hpt NC_008767.1 2080769 2081332 R Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase complement(2080769..2081332) Neisseria meningitidis FAM18 4676531 YP_975951.1 CDS NMC2028 NC_008767.1 2081401 2082225 R catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase complement(2081401..2082225) Neisseria meningitidis FAM18 4676376 YP_975952.1 CDS NMC2029 NC_008767.1 2082284 2082949 D hydrolase 2082284..2082949 Neisseria meningitidis FAM18 4675270 YP_975953.1 CDS NMC2030 NC_008767.1 2083156 2084940 R hypothetical protein complement(2083156..2084940) Neisseria meningitidis FAM18 4675271 YP_975954.1 CDS petC NC_008767.1 2085279 2086082 R cytochrome C1 precursor complement(2085279..2086082) Neisseria meningitidis FAM18 4675695 YP_975955.1 CDS petB NC_008767.1 2086082 2087431 R cytochrome B complement(2086082..2087431) Neisseria meningitidis FAM18 4676153 YP_975956.1 CDS petA NC_008767.1 2087450 2088031 R ubiquinol-cytochrome c reductase iron-sulfur subunit complement(2087450..2088031) Neisseria meningitidis FAM18 4676152 YP_975957.1 CDS NMC2035 NC_008767.1 2088154 2088963 R hypothetical protein complement(2088154..2088963) Neisseria meningitidis FAM18 4675894 YP_975958.1 CDS metR NC_008767.1 2089034 2089963 D transcriptional activator protein METR 2089034..2089963 Neisseria meningitidis FAM18 4675696 YP_975959.1 CDS rpsI NC_008767.1 2090219 2090611 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(2090219..2090611) Neisseria meningitidis FAM18 4676315 YP_975960.1 CDS rplM NC_008767.1 2090621 2091052 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(2090621..2091052) Neisseria meningitidis FAM18 4675134 YP_975961.1 CDS NMC2039 NC_008767.1 2091415 2091720 R hypothetical protein complement(2091415..2091720) Neisseria meningitidis FAM18 4675469 YP_975962.1 CDS NMC2040 NC_008767.1 2091731 2092060 R hypothetical protein complement(2091731..2092060) Neisseria meningitidis FAM18 4674774 YP_975963.1 CDS gpsA NC_008767.1 2092115 2093104 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(2092115..2093104) Neisseria meningitidis FAM18 4674775 YP_975964.1 CDS ppc NC_008767.1 2093227 2095929 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(2093227..2095929) Neisseria meningitidis FAM18 4676522 YP_975965.1 CDS thiF NC_008767.1 2095918 2096865 D thiazole biosynthesis adenylyltransferase ThiF 2095918..2096865 Neisseria meningitidis FAM18 4676081 YP_975966.1 CDS slyX NC_008767.1 2097563 2097787 R hypothetical protein complement(2097563..2097787) Neisseria meningitidis FAM18 4675202 YP_975967.1 CDS NMC2045 NC_008767.1 2097788 2099176 R hypothetical protein complement(2097788..2099176) Neisseria meningitidis FAM18 4675061 YP_975968.1 CDS NMC2046 NC_008767.1 2099262 2100533 R hemk protein complement(2099262..2100533) Neisseria meningitidis FAM18 4675397 YP_975969.1 CDS tldD NC_008767.1 2100598 2102082 R TLDD protein complement(2100598..2102082) Neisseria meningitidis FAM18 4675398 YP_975970.1 CDS NMC2048 NC_008767.1 2102430 2103653 D permease 2102430..2103653 Neisseria meningitidis FAM18 4674865 YP_975971.1 CDS NMC2049 NC_008767.1 2103650 2104750 D oxidoreductase 2103650..2104750 Neisseria meningitidis FAM18 4676348 YP_975972.1 CDS thiE NC_008767.1 2104771 2105388 D thiamin-phosphate pyrophosphorylase 2104771..2105388 Neisseria meningitidis FAM18 4676349 YP_975973.1 CDS NMC2051 NC_008767.1 2105811 2106005 D hypothetical protein 2105811..2106005 Neisseria meningitidis FAM18 4675201 YP_975974.1 CDS thiG NC_008767.1 2106219 2107007 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 2106219..2107007 Neisseria meningitidis FAM18 4675550 YP_975975.1 CDS NMC2053 NC_008767.1 2107770 2108594 R hypothetical protein complement(2107770..2108594) Neisseria meningitidis FAM18 4675199 YP_975976.1 CDS birA NC_008767.1 2108707 2110485 R activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins and catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; bifunctional biotin--[acetyl-CoA-carboxylase] ligase/pantothenate kinase complement(2108707..2110485) Neisseria meningitidis FAM18 4675551 YP_975977.1 CDS NMC2055 NC_008767.1 2110482 2110919 R transferase complement(2110482..2110919) Neisseria meningitidis FAM18 4676524 YP_975978.1 CDS folD NC_008767.1 2111628 2112482 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2111628..2112482 Neisseria meningitidis FAM18 4675532 YP_975979.1 CDS NMC2057 NC_008767.1 2112544 2113125 R hypothetical protein complement(2112544..2113125) Neisseria meningitidis FAM18 4676699 YP_975980.1 CDS NMC2058 NC_008767.1 2113301 2114416 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 2113301..2114416 Neisseria meningitidis FAM18 4675533 YP_975981.1 CDS NMC2059 NC_008767.1 2114509 2115039 R hypothetical protein complement(2114509..2115039) Neisseria meningitidis FAM18 4675687 YP_975982.1 CDS NMC2060 NC_008767.1 2115050 2115394 R hypothetical protein complement(2115050..2115394) Neisseria meningitidis FAM18 4675688 YP_975983.1 CDS NMC2061 NC_008767.1 2115381 2116160 R nuclease complement(2115381..2116160) Neisseria meningitidis FAM18 4675281 YP_975984.1 CDS cysS NC_008767.1 2116243 2118342 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(2116243..2118342) Neisseria meningitidis FAM18 4675282 YP_975985.1 CDS NMC2064 NC_008767.1 2118352 2119401 R ATP-binding protein complement(2118352..2119401) Neisseria meningitidis FAM18 4676019 YP_975986.1 CDS obgE NC_008767.1 2119484 2120638 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(2119484..2120638) Neisseria meningitidis FAM18 4675547 YP_975987.1 CDS cybB NC_008767.1 2121196 2121549 D cytochrome B561 2121196..2121549 Neisseria meningitidis FAM18 4675548 YP_975988.1 CDS NMC2068 NC_008767.1 2121584 2122594 R hypothetical protein complement(2121584..2122594) Neisseria meningitidis FAM18 4676310 YP_975989.1 CDS NMC2069 NC_008767.1 2122506 2122853 D hypothetical protein 2122506..2122853 Neisseria meningitidis FAM18 4675677 YP_975990.1 CDS gmhA NC_008767.1 2122858 2123451 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 2122858..2123451 Neisseria meningitidis FAM18 4675678 YP_975991.1 CDS NMC2071 NC_008767.1 2123515 2124123 D lipoprotein 2123515..2124123 Neisseria meningitidis FAM18 4676392 YP_975992.1 CDS NMC2072 NC_008767.1 2124188 2124781 D hypothetical protein 2124188..2124781 Neisseria meningitidis FAM18 4675421 YP_975993.1 CDS map NC_008767.1 2124821 2125600 D methionine aminopeptidase 2124821..2125600 Neisseria meningitidis FAM18 4675422 YP_975994.1 CDS NMC2074 NC_008767.1 2125755 2126054 D hypothetical protein 2125755..2126054 Neisseria meningitidis FAM18 4676324 YP_975995.1 CDS NMC2075 NC_008767.1 2126106 2126666 D adhesin 2126106..2126666 Neisseria meningitidis FAM18 4674862 YP_975996.1 CDS mqo NC_008767.1 2126854 2128320 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2126854..2128320) Neisseria meningitidis FAM18 4674863 YP_975997.1 CDS NMC2077 NC_008767.1 2128857 2129447 R hypothetical protein complement(2128857..2129447) Neisseria meningitidis FAM18 4676287 YP_975998.1 CDS NMC2078 NC_008767.1 2129508 2130167 R hypothetical protein complement(2129508..2130167) Neisseria meningitidis FAM18 4676101 YP_975999.1 CDS NMC2079 NC_008767.1 2130167 2130376 D hypothetical protein 2130167..2130376 Neisseria meningitidis FAM18 4676102 YP_976000.1 CDS rpsB NC_008767.1 2130577 2131305 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2130577..2131305 Neisseria meningitidis FAM18 4676362 YP_976001.1 CDS tsf NC_008767.1 2131455 2132288 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2131455..2132288 Neisseria meningitidis FAM18 4675267 YP_976002.1 CDS pyrH NC_008767.1 2132505 2133224 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 2132505..2133224 Neisseria meningitidis FAM18 4674754 YP_976003.1 CDS mafA NC_008767.1 2133408 2134370 D adhesin 2133408..2134370 Neisseria meningitidis FAM18 4675766 YP_976004.1 CDS mafB NC_008767.1 2134410 2135792 D adhesin 2134410..2135792 Neisseria meningitidis FAM18 4676326 YP_976005.1 CDS NMC2085 NC_008767.1 2135789 2136106 D hypothetical protein 2135789..2136106 Neisseria meningitidis FAM18 4675933 YP_976006.1 CDS NMC2087 NC_008767.1 2136854 2137060 D hypothetical protein 2136854..2137060 Neisseria meningitidis FAM18 4675705 YP_976007.1 CDS NMC2088 NC_008767.1 2137192 2137443 D hypothetical protein 2137192..2137443 Neisseria meningitidis FAM18 4675706 YP_976008.1 CDS NMC2089 NC_008767.1 2137479 2137811 D hypothetical protein 2137479..2137811 Neisseria meningitidis FAM18 4675673 YP_976009.1 CDS NMC2090 NC_008767.1 2138062 2139048 D mafb protein (fragment) 2138062..2139048 Neisseria meningitidis FAM18 4675674 YP_976010.1 CDS NMC2091 NC_008767.1 2139130 2139477 D LOW G+C REGION; hypothetical protein 2139130..2139477 Neisseria meningitidis FAM18 4675545 YP_976011.1 CDS NMC2092 NC_008767.1 2139480 2139803 D LOW G+C REGION; hypothetical protein 2139480..2139803 Neisseria meningitidis FAM18 4675546 YP_976012.1 CDS NMC2093 NC_008767.1 2139841 2140185 D LOW G+C REGION; hypothetical protein 2139841..2140185 Neisseria meningitidis FAM18 4675416 YP_976013.1 CDS NMC2095 NC_008767.1 2140938 2141156 D hypothetical protein 2140938..2141156 Neisseria meningitidis FAM18 4675409 YP_976014.1 CDS NMC2096 NC_008767.1 2141153 2141512 D LOW G+C REGION; hypothetical protein 2141153..2141512 Neisseria meningitidis FAM18 4675410 YP_976015.1 CDS NMC2097 NC_008767.1 2141588 2141800 D LOW G+C REGION; hypothetical protein 2141588..2141800 Neisseria meningitidis FAM18 4675405 YP_976016.1 CDS NMC2099 NC_008767.1 2142065 2142421 D hypothetical protein 2142065..2142421 Neisseria meningitidis FAM18 4675418 YP_976017.1 CDS NMC2100 NC_008767.1 2142469 2142597 D hypothetical protein 2142469..2142597 Neisseria meningitidis FAM18 4675419 YP_976018.1 CDS NMC2103 NC_008767.1 2143926 2144912 R protease complement(2143926..2144912) Neisseria meningitidis FAM18 4675583 YP_976019.1 CDS NMC2104 NC_008767.1 2144952 2145752 R hypothetical protein complement(2144952..2145752) Neisseria meningitidis FAM18 4675584 YP_976020.1 CDS argG NC_008767.1 2145877 2147220 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 2145877..2147220 Neisseria meningitidis FAM18 4675492 YP_976021.1 CDS NMC2107 NC_008767.1 2147268 2147510 D hypothetical protein 2147268..2147510 Neisseria meningitidis FAM18 4675866 YP_976022.1 CDS NMC2108 NC_008767.1 2147503 2147718 D hypothetical protein 2147503..2147718 Neisseria meningitidis FAM18 4675493 YP_976023.1 CDS NMC2109 NC_008767.1 2147794 2149287 R hypothetical protein complement(2147794..2149287) Neisseria meningitidis FAM18 4675485 YP_976024.1 CDS NMC2110 NC_008767.1 2149399 2150628 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(2149399..2150628) Neisseria meningitidis FAM18 4675486 YP_976025.1 CDS NMC2112 NC_008767.1 2151040 2152887 D hypothetical protein 2151040..2152887 Neisseria meningitidis FAM18 4675543 YP_976026.1 CDS NMC2113 NC_008767.1 2152942 2157111 D hypothetical protein 2152942..2157111 Neisseria meningitidis FAM18 4675544 YP_976027.1 CDS NMC2114 NC_008767.1 2158083 2159540 D peptide transporter 2158083..2159540 Neisseria meningitidis FAM18 4676571 YP_976028.1 CDS prfB NC_008767.1 2160450 2161553 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(2160450..2161553) Neisseria meningitidis FAM18 4676572 YP_976029.1 CDS NMC2118 NC_008767.1 2161656 2162558 R lipoprotein complement(2161656..2162558) Neisseria meningitidis FAM18 4676067 YP_976030.1 CDS NMC2119 NC_008767.1 2162891 2163340 D hypothetical protein 2162891..2163340 Neisseria meningitidis FAM18 4675240 YP_976031.1 CDS NMC2120 NC_008767.1 2163414 2163722 D hypothetical protein 2163414..2163722 Neisseria meningitidis FAM18 4675241 YP_976032.1 CDS NMC2121 NC_008767.1 2163814 2164680 D hypothetical protein 2163814..2164680 Neisseria meningitidis FAM18 4675254 YP_976033.1 CDS NMC2122 NC_008767.1 2164649 2165416 D hypothetical protein 2164649..2165416 Neisseria meningitidis FAM18 4675255 YP_976034.1 CDS NMC2123 NC_008767.1 2165438 2166025 D Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 2165438..2166025 Neisseria meningitidis FAM18 4675350 YP_976035.1 CDS NMC2124 NC_008767.1 2166442 2166882 D lipoprotein 2166442..2166882 Neisseria meningitidis FAM18 4675351 YP_976036.1 CDS NMC2125 NC_008767.1 2167356 2168321 D insertion element IS1655 transposase 2167356..2168321 Neisseria meningitidis FAM18 4675343 YP_976037.1 CDS NMC2126 NC_008767.1 2168865 2169518 D insertion element IS1016 transposase 2168865..2169518 Neisseria meningitidis FAM18 4675344 YP_976038.1 CDS NMC2128 NC_008767.1 2169590 2170192 R hypothetical protein complement(2169590..2170192) Neisseria meningitidis FAM18 4676218 YP_976039.1 CDS purD NC_008767.1 2170226 2171497 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(2170226..2171497) Neisseria meningitidis FAM18 4676219 YP_976040.1 CDS NMC2130 NC_008767.1 2171655 2171972 D hypothetical protein 2171655..2171972 Neisseria meningitidis FAM18 4676024 YP_976041.1 CDS NMC2131 NC_008767.1 2172024 2172635 R hypothetical protein complement(2172024..2172635) Neisseria meningitidis FAM18 4676256 YP_976042.1 CDS etfA NC_008767.1 2172698 2173633 R electron transfer flavoprotein subunit alpha complement(2172698..2173633) Neisseria meningitidis FAM18 4676257 YP_976043.1 CDS etfB NC_008767.1 2173644 2174393 R electron transfer flavoprotein subunit beta complement(2173644..2174393) Neisseria meningitidis FAM18 4675890 YP_976044.1 CDS NMC2134 NC_008767.1 2174619 2175587 R lipopolysaccharide heptosyltransferase I complement(2174619..2175587) Neisseria meningitidis FAM18 4675897 YP_976045.1 CDS pncA NC_008767.1 2175625 2176260 R nicotinamidase complement(2175625..2176260) Neisseria meningitidis FAM18 4676307 YP_976046.1 CDS NMC2136 NC_008767.1 2176375 2177055 D hypothetical protein 2176375..2177055 Neisseria meningitidis FAM18 4676108 YP_976047.1 CDS NMC2137 NC_008767.1 2177313 2178350 R glyceraldehyde 3-phosphate dehydrogenase C complement(2177313..2178350) Neisseria meningitidis FAM18 4676308 YP_976048.1 CDS mutS NC_008767.1 2178761 2181355 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2178761..2181355 Neisseria meningitidis FAM18 4676244 YP_976049.1 CDS NMC2139 NC_008767.1 2181478 2181969 R acetyltransferase complement(2181478..2181969) Neisseria meningitidis FAM18 4676214 YP_976050.1 CDS NMC2140 NC_008767.1 2181973 2182371 R hypothetical protein complement(2181973..2182371) Neisseria meningitidis FAM18 4676245 YP_976051.1 CDS gltX NC_008767.1 2182389 2183783 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2182389..2183783) Neisseria meningitidis FAM18 4676258 YP_976052.1 CDS NMC2142 NC_008767.1 2183899 2184555 R hypothetical protein complement(2183899..2184555) Neisseria meningitidis FAM18 4676574 YP_976053.1 CDS NMC2143 NC_008767.1 2184552 2184905 R oxidoreductase complement(2184552..2184905) Neisseria meningitidis FAM18 4676259 YP_976054.1 CDS NMC2144 NC_008767.1 2185029 2185511 D periplasmic thiredoxin 2185029..2185511 Neisseria meningitidis FAM18 4676265 YP_976055.1 CDS ftsE NC_008767.1 2185705 2186355 D ABC transporter ATP-binding protein 2185705..2186355 Neisseria meningitidis FAM18 4676266 YP_976056.1 CDS ftsX NC_008767.1 2186352 2187269 D ABC transporter integral membrane protein 2186352..2187269 Neisseria meningitidis FAM18 4676657 YP_976057.1 CDS NMC2147 NC_008767.1 2187330 2187608 D hypothetical protein 2187330..2187608 Neisseria meningitidis FAM18 4676665 YP_976058.1 CDS pgk NC_008767.1 2187675 2188853 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(2187675..2188853) Neisseria meningitidis FAM18 4676170 YP_976059.1 CDS murA NC_008767.1 2188934 2190187 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(2188934..2190187) Neisseria meningitidis FAM18 4676143 YP_976060.1 CDS NMC2150 NC_008767.1 2190551 2191525 R transmembrane transport protein complement(2190551..2191525) Neisseria meningitidis FAM18 4676267 YP_976061.1 CDS NMC2151 NC_008767.1 2191558 2192019 R hypothetical protein complement(2191558..2192019) Neisseria meningitidis FAM18 4676171 YP_976062.1 CDS kdtA NC_008767.1 2192048 2193385 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(2192048..2193385) Neisseria meningitidis FAM18 4676293 YP_976063.1 CDS gnd NC_008767.1 2193382 2194830 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2193382..2194830) Neisseria meningitidis FAM18 4676406 NMC_t01 tRNA NMC_t01 NC_008767.1 48280 48356 D tRNA-Ile 48280..48356 Neisseria meningitidis FAM18 4881656 NMC_t02 tRNA NMC_t02 NC_008767.1 48362 48437 D tRNA-Ala 48362..48437 Neisseria meningitidis FAM18 4881658 NMC_t03 tRNA NMC_t03 NC_008767.1 119922 120005 D tRNA-Tyr 119922..120005 Neisseria meningitidis FAM18 4881618 NMC_t04 tRNA NMC_t04 NC_008767.1 120036 120109 D tRNA-Gly 120036..120109 Neisseria meningitidis FAM18 4881662 NMC_t05 tRNA NMC_t05 NC_008767.1 120119 120193 D tRNA-Thr 120119..120193 Neisseria meningitidis FAM18 4881617 NMC_t06 tRNA NMC_t06 NC_008767.1 121433 121508 D tRNA-Trp 121433..121508 Neisseria meningitidis FAM18 4881651 NMC_t07 tRNA NMC_t07 NC_008767.1 175562 175637 R tRNA-Thr complement(175562..175637) Neisseria meningitidis FAM18 4881603 NMC_t08 tRNA NMC_t08 NC_008767.1 199219 199294 D tRNA-Val 199219..199294 Neisseria meningitidis FAM18 4881622 NMC_t09 tRNA NMC_t09 NC_008767.1 199327 199403 D tRNA-Asp 199327..199403 Neisseria meningitidis FAM18 4881640 NMC_t10 tRNA NMC_t10 NC_008767.1 199443 199518 D tRNA-Val 199443..199518 Neisseria meningitidis FAM18 4881639 NMC_t11 tRNA NMC_t11 NC_008767.1 199551 199627 D tRNA-Asp 199551..199627 Neisseria meningitidis FAM18 4881644 NMC_t12 tRNA NMC_t12 NC_008767.1 335223 335308 R tRNA-Leu complement(335223..335308) Neisseria meningitidis FAM18 4881650 NMC_t13 tRNA NMC_t13 NC_008767.1 382212 382287 D tRNA-Lys 382212..382287 Neisseria meningitidis FAM18 4881636 NMC_t14 tRNA NMC_t14 NC_008767.1 490146 490222 R tRNA-Pro complement(490146..490222) Neisseria meningitidis FAM18 4881616 NMC_t15 tRNA NMC_t15 NC_008767.1 617922 617998 D tRNA-Pro 617922..617998 Neisseria meningitidis FAM18 4881659 NMC_t16 tRNA NMC_t16 NC_008767.1 649532 649624 D tRNA-Ser 649532..649624 Neisseria meningitidis FAM18 4881608 NMC_t17 tRNA NMC_t17 NC_008767.1 694131 694207 D tRNA-Val 694131..694207 Neisseria meningitidis FAM18 4881646 NMC_t18 tRNA NMC_t18 NC_008767.1 715824 715900 D tRNA-Arg 715824..715900 Neisseria meningitidis FAM18 4881648 NMC_t19 tRNA NMC_t19 NC_008767.1 715918 715992 D tRNA-Glu 715918..715992 Neisseria meningitidis FAM18 4881635 NMC_t20 tRNA NMC_t20 NC_008767.1 820125 820200 D tRNA-Thr 820125..820200 Neisseria meningitidis FAM18 4881647 NMC_t21 tRNA NMC_t21 NC_008767.1 820235 820310 D tRNA-Thr 820235..820310 Neisseria meningitidis FAM18 4881643 NMC_t22 tRNA NMC_t22 NC_008767.1 825795 825870 D tRNA-Gln 825795..825870 Neisseria meningitidis FAM18 4881649 NMC_t23 tRNA NMC_t23 NC_008767.1 825879 825954 D tRNA-Gln 825879..825954 Neisseria meningitidis FAM18 4881642 NMC_t24 tRNA NMC_t24 NC_008767.1 825963 826038 D tRNA-Gln 825963..826038 Neisseria meningitidis FAM18 4881661 NMC_t25 tRNA NMC_t25 NC_008767.1 846817 846907 D tRNA-Ser 846817..846907 Neisseria meningitidis FAM18 4881652 NMC_t26 tRNA NMC_t26 NC_008767.1 846985 847074 D tRNA-Ser 846985..847074 Neisseria meningitidis FAM18 4881620 NMC_t27 tRNA NMC_t27 NC_008767.1 1082581 1082671 R tRNA-Ser complement(1082581..1082671) Neisseria meningitidis FAM18 4881664 NMC_t28 tRNA NMC_t28 NC_008767.1 1082707 1082793 R tRNA-Leu complement(1082707..1082793) Neisseria meningitidis FAM18 4881615 NMC_t29 tRNA NMC_t29 NC_008767.1 1082829 1082915 R tRNA-Leu complement(1082829..1082915) Neisseria meningitidis FAM18 4881613 NMC_t30 tRNA NMC_t30 NC_008767.1 1131226 1131310 R tRNA-Leu complement(1131226..1131310) Neisseria meningitidis FAM18 4881653 NMC_t31 tRNA NMC_t31 NC_008767.1 1388104 1388180 D tRNA-Arg 1388104..1388180 Neisseria meningitidis FAM18 4881654 NMC_t32 tRNA NMC_t32 NC_008767.1 1388198 1388272 D tRNA-Glu 1388198..1388272 Neisseria meningitidis FAM18 4881629 NMC_t33 tRNA NMC_t33 NC_008767.1 1465704 1465779 R tRNA-Asn complement(1465704..1465779) Neisseria meningitidis FAM18 4881665 NMC_t34 tRNA NMC_t34 NC_008767.1 1517896 1517980 R tRNA-Leu complement(1517896..1517980) Neisseria meningitidis FAM18 4881625 NMC_t35 tRNA NMC_t35 NC_008767.1 1528965 1529054 R tRNA-Leu complement(1528965..1529054) Neisseria meningitidis FAM18 4881633 NMC_t36 tRNA NMC_t36 NC_008767.1 1529157 1529230 R tRNA-Cys complement(1529157..1529230) Neisseria meningitidis FAM18 4881626 NMC_t37 tRNA NMC_t37 NC_008767.1 1529256 1529331 R tRNA-Gly complement(1529256..1529331) Neisseria meningitidis FAM18 4881619 NMC_t38 tRNA NMC_t38 NC_008767.1 1529353 1529428 R tRNA-Gly complement(1529353..1529428) Neisseria meningitidis FAM18 4881631 NMC_t39 tRNA NMC_t39 NC_008767.1 1529452 1529527 R tRNA-Gly complement(1529452..1529527) Neisseria meningitidis FAM18 4881630 NMC_t40 tRNA NMC_t40 NC_008767.1 1529553 1529628 R tRNA-Gly complement(1529553..1529628) Neisseria meningitidis FAM18 4881634 NMC_t41 tRNA NMC_t41 NC_008767.1 1560819 1560894 D tRNA-Glu 1560819..1560894 Neisseria meningitidis FAM18 4881596 NMC_t42 tRNA NMC_t42 NC_008767.1 1603286 1603361 R tRNA-Ala complement(1603286..1603361) Neisseria meningitidis FAM18 4881611 NMC_t43 tRNA NMC_t43 NC_008767.1 1603367 1603443 R tRNA-Ile complement(1603367..1603443) Neisseria meningitidis FAM18 4881614 NMC_t44 tRNA NMC_t44 NC_008767.1 1628770 1628845 D tRNA-Arg 1628770..1628845 Neisseria meningitidis FAM18 4881612 NMC_t45 tRNA NMC_t45 NC_008767.1 1652028 1652103 D tRNA-Met 1652028..1652103 Neisseria meningitidis FAM18 4881595 NMC_t46 tRNA NMC_t46 NC_008767.1 1700709 1700784 R tRNA-Asn complement(1700709..1700784) Neisseria meningitidis FAM18 4881660 NMC_t47 tRNA NMC_t47 NC_008767.1 1792678 1792754 D tRNA-Met 1792678..1792754 Neisseria meningitidis FAM18 4881663 NMC_t48 tRNA NMC_t48 NC_008767.1 1792762 1792837 D tRNA-Ala 1792762..1792837 Neisseria meningitidis FAM18 4881628 NMC_t49 tRNA NMC_t49 NC_008767.1 1850468 1850543 R tRNA-Phe complement(1850468..1850543) Neisseria meningitidis FAM18 4881627 NMC_t50 tRNA NMC_t50 NC_008767.1 1876971 1877042 R tRNA-Arg complement(1876971..1877042) Neisseria meningitidis FAM18 4881624 NMC_t51 tRNA NMC_t51 NC_008767.1 1911076 1911151 R tRNA-Ala complement(1911076..1911151) Neisseria meningitidis FAM18 4881637 NMC_t52 tRNA NMC_t52 NC_008767.1 1911157 1911233 R tRNA-Ile complement(1911157..1911233) Neisseria meningitidis FAM18 4881641 NMC_t53 tRNA NMC_t53 NC_008767.1 2045909 2045984 R tRNA-Ala complement(2045909..2045984) Neisseria meningitidis FAM18 4881600 NMC_t54 tRNA NMC_t54 NC_008767.1 2045990 2046066 R tRNA-Ile complement(2045990..2046066) Neisseria meningitidis FAM18 4881598 NMC_t55 tRNA NMC_t55 NC_008767.1 2074783 2074859 D tRNA-Met 2074783..2074859 Neisseria meningitidis FAM18 4881667 NMC_t56 tRNA NMC_t56 NC_008767.1 2111124 2111199 R tRNA-His complement(2111124..2111199) Neisseria meningitidis FAM18 4881666 NMC_t57 tRNA NMC_t57 NC_008767.1 2111227 2111303 R tRNA-Arg complement(2111227..2111303) Neisseria meningitidis FAM18 4881597 NMC_t58 tRNA NMC_t58 NC_008767.1 2111328 2111405 R tRNA-Pro complement(2111328..2111405) Neisseria meningitidis FAM18 4881604 NMC_t59 tRNA NMC_t59 NC_008767.1 2190407 2190482 R tRNA-Lys complement(2190407..2190482) Neisseria meningitidis FAM18 4881607 NMC_r01 rRNA NMC_r01 NC_008767.1 46638 48181 D 16S ribosomal RNA 46638..48181 Neisseria meningitidis FAM18 4881645 NMC_r02 rRNA NMC_r02 NC_008767.1 48845 51735 D 23S ribosomal RNA 48845..51735 Neisseria meningitidis FAM18 4881657 NMC_r03 rRNA NMC_r03 NC_008767.1 51829 51945 D 5S ribosomal RNA 51829..51945 Neisseria meningitidis FAM18 4881655 NMC_r04 rRNA NMC_r04 NC_008767.1 1599779 1599895 R 5S ribosomal RNA complement(1599779..1599895) Neisseria meningitidis FAM18 4881609 NMC_r05 rRNA NMC_r05 NC_008767.1 1599989 1602878 R 23S ribosomal RNA complement(1599989..1602878) Neisseria meningitidis FAM18 4881610 NMC_r06 rRNA NMC_r06 NC_008767.1 1603542 1605085 R 16S ribosomal RNA complement(1603542..1605085) Neisseria meningitidis FAM18 4881621 NMC_r07 rRNA NMC_r07 NC_008767.1 1907566 1907682 R 5S ribosomal RNA complement(1907566..1907682) Neisseria meningitidis FAM18 4881623 NMC_r08 rRNA NMC_r08 NC_008767.1 1907776 1910666 R 23S ribosomal RNA complement(1907776..1910666) Neisseria meningitidis FAM18 4881638 NMC_r09 rRNA NMC_r09 NC_008767.1 1911332 1912875 R 16S ribosomal RNA complement(1911332..1912875) Neisseria meningitidis FAM18 4881602 NMC_r10 rRNA NMC_r10 NC_008767.1 2042401 2042517 R 5S ribosomal RNA complement(2042401..2042517) Neisseria meningitidis FAM18 4881605 NMC_r11 rRNA NMC_r11 NC_008767.1 2042611 2045501 R 23S ribosomal RNA complement(2042611..2045501) Neisseria meningitidis FAM18 4881601 NMC_r12 rRNA NMC_r12 NC_008767.1 2046165 2047708 R 16S ribosomal RNA complement(2046165..2047708) Neisseria meningitidis FAM18 4881599