-- dump date   	20140619_163811
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_002341564.1	NMA0001, unknown, len: 106 aa
YP_002341565.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002341566.1	NMA0003, unknown, len: 113 aa
YP_002341567.1	NMA0004, unknown, len: 191 aa; similar to hypothetical proteins e.g. Y977_HAEIN HI0977 (191 aa),fasta scores; E(): 0; 80.5% identity in 190 aa overlap, and to proteins involved in cell cycle e.g. TR:O54679 (EMBL:AF036487) Lactococcus lactis Plasmid pNZ4000  mobilization protein (200 aa), fasta scores; E(): 0, 55.1% identity in 167 aa overlap, and FIC_ECOLI cell filamentation protein FIC (200 aa), fasta scores; E(): 0.093, 29.4% identity in 126 aa overlap
YP_002341568.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002341569.1	NMA0006, nuoJ, NADH dehydrogenase I chain J, len: 223 aa; similar to many e.g. NUOJ_RHOCA NADH dehydrogenase I chain J (EC 1.6.5.3) (202 aa), fatsa scores; E(): 9.7e-21; 41.3% identity in 201 aa overlap. Contains Pfam match to entry PF00499 oxidored_q3,NADH-ubiquinone/plastoquinone oxidoreductase chain 6
YP_002341570.1	NMA0007, unknown, len: 235 aa
YP_002341571.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002341572.1	NMA0009, nuoH, NADH dehydrogenase I chain H, len: 358 aa; similar to many e.g. NUOH_RHOCA NADH dehydrogenase I chain H (EC 1.6.5.3) (345 aa), fasta scores; E(): 0,46.4% identity in 332 aa overlap. Contains Pfam match to entry PF00146 NADHdh, NADH dehydrogenases, and PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2
YP_002341573.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002341574.1	NMA0011, unknown, len: 89 aa; similar to TR:O33368 (EMBL:AJ002423) N.g. hypothetical 11.4 kd protein (94 aa),fasta scores; E(): 1.1e-16; 53.0% identity in 83 aa overlap. Also similar to NMA0292, fasta scores; E(): 5.4e-19; 54.2% identity in 83 aa overlap
YP_002341575.1	NMA0013, unknown, len: 145 aa. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002341576.1	NMA0014, nuoF, NADH dehydrogenase I chain F, len: 433 aa; similar to many e.g. NQO1_THETH NADH-ubiquinone oxidoreductase chain 1 (EC 1.6.5.3) (438 aa), fasta scores; E(): 0; 50.0% identity in 414 aa overlap, and SW:NUOF_ECOLI P31979 NADH dehydrogenase I chain F (EC 1.6.5.3) (445 aa), blastp scores Expect = 2.8e-93. Contains PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2
YP_002341577.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002341578.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002341579.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002341580.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_002341581.1	NMA0019, nuoA, NADH dehydrogenase I chain A, len: 118 aa; similar to many eg. NU3M_PLASU NADH-ubiquinone oxidoreductase chain 3 (EC 1.6.5.3) (117 aa), fastscores; E(): 8.3e-28, 55.3% identity in 114 aa overlap, and NUOA_ECOLI P33597 NADH dehydrogenase I chain A (EC 1.6.5.3) (147 aa), blastp scores; Expect = 7.1e-17; 33% identity in 112 aa overlap. Contains Pfam match to entry PF00507 oxidored_q4, NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
YP_002341582.1	NMA0020, probable integral membrane protein, len: 494 aa; weak similarity to TR:O33279 (EMBL:AL008687) Mycobacterium tuberculosis  spermidine synthase speE (523 aa), fasta scores; E(): 0.00015, 24.1% identity in 406 aa overlap. Contains several membrane spanning domains in N-terminal half
YP_002341583.1	NMA0021, probable integral membrane protein, len: 206 aa; weak similarity to TR:CAB42042 (EMBL:AL049754) Streptomyces coelicolor  spermidine synthase SCH10.33c (554 aa), fasta scores; E(): 0.0013, 25.8% identity in 194 aa overlap. Contains several membrane spanning domains
YP_002341584.1	NMA0022,  transposase for IS1016, len: 125 aa; 91.3% identity to TR:AAD31037 (EMBL:AF142582) N.g. MAFI (104 aa), and highly similar to part of TR:Q48234 (EMBL:X59756) Haemophilus influenzae insertion sequence IS1016-V6 (191 aa), fasta scores; E(): 2e-12, 67.9% identity in 53 aa overlap
YP_002341585.1	NMA0023, unknown, len: 109 aa
YP_002341586.1	NMA0024, unknown, len: 71 aa; similar to NMA0323,fasta scores; E(): 5.6e-11, 46.4% identity in 69 aa overlap
YP_002341587.1	NMA0025, unknown, len: 179 aa
YP_002341588.1	NMA0027, uvrD, probable DNA helicase II, len 735 aa; similar to e.g. UVRD_ECOLI DNA helicase II (EC 3.6.1.-) (720 aa), fasta scores; E(): 0, 48.0% identity in 736 aa overlap. Contains Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002341589.1	NMA0028, unknown, len: 215 aa; similar to hypothetical proteins e.g. YBGJ_HAEIN HI1731 (213 aa),fasta scores; E(): 0, 59.0% identity in 212 aa overlap
YP_002341590.1	NMA0029, unknown, len: 309 aa; similar to hypothetical proteins e.g. YBGK_HAEIN HI1730 (309 aa),fasta scores; E(): 0, 59.6% identity in 307 aa overlap. Also some similarity to part of DUR1_YEAST urea amidolyase (1835 aa), fasta scores; E(): 2.1e-12, 27.6% identity in 323 aa overlap
YP_002341591.1	NMA0030, unknown, len: 245 aa; similar to hypothetical proteins e.g. YBGL_HAEIN HI1729 (257 aa),fasta scores; E(): 0, 59.6% identity in 245 aa overlap, and to LAMB_EMENI Emericella nidulans lactam utilization protein LAMB (262 aa), fasta scores; E(): 3.3e-13, 39.1% identity in 128 aa overlap
YP_002341592.1	NMA0031, probable transmembrane transport protein,len: 397 aa; similar to many diverse transport proteins e.g. BRNQ_HAEIN branched-chain amino acid transport system carrier protein (436 aa), fasta scores; E(): 6.7e-06,23.7% identity in 371 aa overlap, and TYRP_HAEIN tyrosine-specific transport protein 1 (400 aa), fasta scores; E(): 0.25, 24.9% identity in 213 aa overlap
YP_002341593.1	NMA0032, unknown, len: 230 aa; similar to NMA0403,fasta scores; E(): 0, 53.5% identity in 230 aa overlap
YP_002341594.1	NMA0033, probable transposase for IS1655, len: 321 aa; similar to many e.g. TRA4_BACFR transposase for insertion sequence element IS4351 (326 aa), fasta scores; E(): 0, 41.6% identity in 310 aa overlap. Contains Pfam match to entry PF01460 Transposase_4, Transposase IS30 family, score 373.60, E-value 2e-108
YP_002341595.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
YP_002341596.1	NMA0036, unknown, len: 111 aa
YP_002341597.1	NMA0037, unknown, len: 157 aa
YP_002341598.1	NMA0038, unknown, len: 93 aa; highly similar to NMA2116, fasta scores; E(): 0, 88.2% identity in 93 aa overlap
YP_002341599.1	NMA0039, unknown, len: 107 aa
YP_002341600.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_002341601.1	carries the fatty acid chain in fatty acid biosynthesis
YP_002341602.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002341603.1	NMA0046, probable transmembrane transport protein,len: 318 aa; similar to members of the SBF family e.g. TR:O34524 (EMBL:AF027868) B. subtilis  transporter YOCS (321 aa), fasta scores; E(): 0, 37.7% identity in 305 aa overlap, and NTCI_HUMAN ileal sodium/bile acid cotransporter (348 aa), fasta scores; E(): 2.4e-13, 27.8% identity in 252 aa overlap
YP_002341604.1	NMA0047, probable transmembrane transport protein,len: 405 aa; similar to e.g. YHJX_ECOLI hypothetical protein (402 aa), fasta scores; E(): 7.9e-17, 24.7% identity in 397 aa overlap, and TR:Q51330 (EMBL:U40075) Oxalobacter formigenes oxalate:formate antiport protein (418 aa), fasta scores; E(): 1.5e-16, 26.8% identity in 377 aa overlap
YP_002341605.1	NMA0048, pglA, glycosyltransferase, len: 377 aa; almost identical to TR:O87893 (EMBL:U73942) N.m. glycosyltransferase involved in pilin glycosylation (376 aa), fasta scores; E(): 0, 98.9% identity in 377 aa overlap. Also similar to many others e.g. TR:Q53982 (EMBL:M96064) Shigella dysenteriae RFP protein (377 aa),fasta scores; E(): 0, 48.5% identity in 377 aa overlap,Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1, and (g)14 tract at aa 246
YP_002341606.1	NMA0049, probable RNA polymerase sigma factor, len: 283 aa; similar to many members of the sigma-54 family e.g. RP54_ALCEU RNA polymerase sigma-54 factor (493 aa),fasta scores; E(): 4.7e-11, 31.4% identity in 303 aa overlap, and RP54_ECOLI RNA polymerase sigma-54 factor (477 aa), fasta scores; E(): 0.034, 32.2% identity in 273 aa overlap. Contains PS00718 Sigma-54 factors family signature 2
YP_002341607.1	NMA0050, katA, catalase, len: 504 aa; highly similar to many e.g. CATA_HAEIN catalase (EC 1.11.1.6) (508 aa), fasta scores; E(): 0, 91.7% identity in 507 aa overlap. Contains Pfam match to entry PF00199 catalase,Catalase, PS00438 Catalase proximal active site signature, and PS00437 Catalase proximal heme-ligand signature
YP_002341608.1	NMA0052, probable integral membrane protein, len: 188 aa; similar to hypothetical proteins belonging to the UPF0059 family e.g. YEBN_ECOLI (206 aa), fasta scores; E(): 1.5e-29, 48.9% identity in 186 aa overlap
YP_002341609.1	NMA0054, prlC, probable oligopeptidase A, len: 678 aa; similar to many e.g. OPDA_ECOLI oligopeptidase A (EC 3.4.24.70) (680 aa), fasta scores; E(): 0, 49.9% identity in 679 aa overlap. Contains Pfam match to entry PF01432 Peptidase_M3, Peptidase family M3, and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002341610.1	NMA0055, probable integral membrane protein, len: 328 aa
YP_002341611.1	negatively supercoils closed circular double-stranded DNA
YP_002341612.1	NMA0057, sdaA, probable L-serine dehydratase, len: 439 aa; similar to many e.g. SDHL_STRCO L-serine dehydratase (EC 4.3.1.17) (455 aa), fasta scores; E(): 0,51.7% identity in 433 aa overlap
YP_002341613.1	NMA0060, probable transmembrane transport protein,len; 658 aa; similar to e.g. KEFB_ECOLI glutathione-regulated potassium-efflux system protein KEFB (601 aa), fasta scores; E(): 0, 33.6% identity in 563 aa overlap, Contains PS00213 Lipocalin signature
YP_002341614.1	NMA0061, probable ferredoxin, len: 279 aa; similar to e.g. YDGM_ECOLI  ferredoxin-like protein (192 aa), fasta scores; E(): 2.7e-23, 52.9% identity in 153 aa overlap. Contains Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains., and 2x PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature
YP_002341615.1	NMA0062, gapA, glyceraldehyde 3-phosphate dehydrogenase, len: 343 aa; similar to many e.g. G3PP_ALCEU glyceraldehyde 3-phosphate dehydrogenase,plasmid (EC 1.1.1.2842) (336 aa), fasta scores; E(): 0,67.4% identity in 331 aa overlap. Contains Pfam match to entry PF00044 gpdh, glyceraldehyde 3-phosphate dehydrogenases, and PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. Also similar to gapC, NMA0246,fasta scores; E(): 0, 50.7% identity in 341 aa overlap
YP_002341616.1	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys
YP_002341617.1	NMA0064, fur, ferric uptake regulation protein,len: 144 aa; almost identical to FUR_NEIME ferric uptake regulation protein (144 aa), fasta scores; E(): 0, 99.3% identity in 144 aa overlap. Contains Pfam match to entry PF01475 FUR, Ferric uptake regulator family E-value 1.3e-68
YP_002341618.1	NMA0065, probable lipoprotein, len: 125 aa; similar to hypothetical proteins e.g. SMPA_ECOLI small protein A (113 aa), fasta scores; E(): 1.5e-06, 39.8% identity in 103 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341619.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_002341620.1	NMA0067, unknown, len: 99 aa
YP_002341621.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
YP_002341622.1	NMA0070, rluC, probable ribosomal large subunit pseudouridine synthase C, len: 330 aa; similar to many e.g. RLUC_ECOLI ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) (319 aa), fasta scores; E(): 0,53.7% identity in 311 aa overlap. Contains Pfam match to entry PF00849 YABO, Hypothetical yabO/yceC/sfhB family, and PS01129 Hypothetical yabO/yceC/sfhB family signature
YP_002341623.1	NMA0071, rne, probable ribonuclease E, len: 919 aa; similar to e.g. RNE_ECOLI ribonuclease E (EC 3.1.4.-) (1061 aa), fasta scores; E(): 0, 44.3% identity in 979 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain
YP_002341624.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
YP_002341625.1	NMA0073, probable amino-acid transport protein,len: 475 aa; similar to e.g. ALST_BACSU amino acid carrier protein ALST (465 aa), fasta scores; E(): 0, 49.3% identity in 469 aa overlap, and DAGA_ALTHA Na(+)-linked D-alanine glycine permease (542 aa), fasta scores; E(): 0,44.2% identity in 303 aa overlap. Contains Pfam match to entry PF01235 Na_Ala_symp, Sodium:alanine symporter family, PS00873 Sodium:alanine symporter family signature, and (cgc)5 sequence at aa 291
YP_002341626.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_002341627.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_002341628.1	NMA0076, parA family protein, len: 257 aa; similar to many e.g. SOJ_BACSU SOJ protein (253 aa), fasta scores; E(): 0, 55.6% identity in 248 aa overlap. Contains Pfam match to entry PF00991 ParA, ParA family ATPase
YP_002341629.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_002341630.1	NMA0078, probable integral membrane protein, len: 161 aa. Contains four probable transmembrane domains
YP_002341631.1	NMA0079, probable integral membrane protein, len: 375 aa; similar to hypothetical proteins e.g. YEEA_ECOLI (352 aa), fasta scores; E(): 1.9e-20, 27.9% identity in 348 aa overlap
YP_002341632.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_002341633.1	NMA0081, uppS,  UDP diphosphate synthase, len: 248 aa; similar to e.g. UPPS_ECOLI UDP PYROPHOSPHATE SYNTHETASE (EC 2.5.1.31) (252 aa), fasta scores; E(): 0, 51.6% identity in 246 aa overlap, and to TR:O82827 (EMBL:AB004319) Micrococcus luteus UDP diphosphate synthase (249 aa), fasta scores; E(): 0, 45.4% identity in 229 aa overlap. Contains Pfam match to entry PF01255 UPF0015, Uncharacterized protein family UPF0015, score 372.10, E-value 5.6e-108, and PS01066 Uncharacterized protein family UPF0015 signature
YP_002341634.1	NMA0082, cdsA, probable phosphatidate cytidylyltransferase, len: 265 aa; similar to many e.g. CDSA_PSEAE phosphatidate cytidylyltransferase (EC 2.7.7.41) (271 aa), fasta scores; E(): 0, 44.2% identity in 269 aa overlap. Contains Pfam match to entry PF01148 Cytidylyltrans, Phosphatidate cytidylyltransferase, and PS01315 Phosphatidate cytidylyltransferase signature
YP_002341635.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_002341636.1	NMA0084, probable integral membrane protein, len: 446 aa; similar to many hypothetical proteins e.g. YAEL_ECOLI (450 aa), fasta scores; E(): 0, 38.4% identity in 456 aa overlap. Contains 2x Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF), and PS00142 Neutral zinc metallopeptidases, zinc-binding region signature
YP_002341637.1	NMA0085, omp85, outer membrane protein OMP85, len: 797 aa; almost identical to TR:O30912 (EMBL:AF021245) N.m. strain HH outer membrane protein OMP85 (797 aa), fasta scores; E(): 0, 99.6% identity in 797 aa overlap, and similar to e.g. D152_HAEIN protective surface antigen D15 precursor (795 aa), fasta scores; E(): 0, 31.6% identity in 813 aa overlap. Contains Pfam match to entry PF01103 Bac_surface_Ag, Bacterial surface antigen, PS00017 ATP/GTP-binding site motif A (P-loop), and N-terminal signal sequence
YP_002341638.1	NMA0086,  outer membrane protein, len: 166 aa; similar to e.g. OMPH_YEREN cationic 19 kd outer membrane protein precursor (164 aa), fasta scores; E(): 1.1e-05, 25.0% identity in 164 aa overlap, and HLPA_ECOLI histone-like protein HLP-1 precursor (161 aa), fasta scores; E(): 0.00038, 26.3% identity in 167 aa overlap. Contains N-terminal signal sequence
YP_002341639.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_002341640.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_002341641.1	NMA0089, unknown, len; 226 aa
YP_002341642.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
YP_002341643.1	NMA0091, probable amino-acid transporter, len: 463 aa; similar to members of the sodium:alanine symporter family e.g. Y883_HAEIN P44917 hypothetical protein HI0883 (456 aa), fasta scores; E(): 0, 52.6% identity in 454 aa overlap, and DAGA_ALTHA P30144 Na(+)-linked D-alanine glycine permease (542 aa), fasta scores; E(): 0, 36.1% identity in 540 aa overlap. Contains Pfam match to entry PF01235 Na_Ala_symp, Sodium:alanine symporter family, and PS00873 Sodium:alanine symporter family signature E-value 6e-162
YP_002341644.1	catalyzes the oxidative deamination of D-amino acids
YP_002341645.1	NMA0093, probable integral membrane protein, len: 269 aa; similar to hypothetical proteins e.g. YGIE_ECOLI P24198 (257 aa), fasta scores; E(): 5.8e-28, 36.8% identity in 261 aa overlap
YP_002341646.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_002341647.1	NMA0095, unknown, len: 51 aa
YP_002341648.1	NMA0096, unknown, len: 129 aa; similar to NMA1028,fasta scores; E(): 1.7e-19, 45.2% identity in 126 aa overlap, NMA1027, fasta scores; E(): 1.6e-12, 36.4% identity in 118 aa overlap, NMA1026, fasta scores; E(): 5.4e-10, 30.4% identity in 125 aa overlap, and the N-terminus of NMA1636, fasta scores; E(): 1.4e-06, 44.3% identity in 61 aa overlap
YP_002341649.1	NMA0098, oxyR,  hydrogen peroxide-inducible genes activator, len: 306 aa; similar to e.g. OXYR_ECOLI P11721 hydrogen peroxide-inducible genes activator (305 aa), fasta scores; E(): 0, 37.5% identity in 280 aa overlap. Contains Pfam match to entry PF00126 HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family, and PS00044 Bacterial regulatory proteins, lysR family signature
YP_002341650.1	works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell
YP_002341651.1	NMA0100, minD, probable septum site-determining protein, len: 271 aa; highly similar to e.g. MIND_ECOLI P18197 septum site-determining protein MIND (269 aa),fasta scores; E(): 0, 73.8% identity in 271 aa overlap. Contains Pfam match to entry PF00991 ParA, ParA family ATPase, and PS00017 ATP/GTP-binding site motif A (P-loop) E-value 5.8e-05
YP_002341652.1	blocks the formation of polar Z-ring septums
YP_002341653.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_002341654.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_002341655.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_002341656.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_002341657.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_002341658.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_002341659.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_002341660.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_002341661.1	late assembly protein
YP_002341662.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_002341663.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_002341664.1	binds 5S rRNA along with protein L5 and L25
YP_002341665.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_002341666.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_002341667.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_002341668.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_002341669.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_002341670.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_002341671.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_002341672.1	one of the stabilizing components for the large ribosomal subunit
YP_002341673.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_002341674.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_002341675.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_002341676.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_002341677.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_002341678.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_002341679.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_002341680.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_002341681.1	NMA0131,  ATP/GTP binding protein, len: 227 aa; some similarity in ATP/GTP binding domain to TR:Q9ZL99 (EMBL:AE001499) Helicobacter pylori J99 hypothetical protein (404 aa), fasta scores; E(): 0.00018, 37.3% identity in 102 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Also similar to upstream gene NMA0132 (43.2% identity in 229 aa overlap)
YP_002341682.1	NMA0132,  ATP/GTP binding protein, len: 351 aa; similar to downstream gene NMA0131 (43.2% identity in 229 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002341683.1	NMA0132A, unknown, len: 86 aa; contains G(9) homopolymeric tract
YP_002341684.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_002341685.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002341686.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_002341687.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_002341688.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_002341689.1	NMA0138, unknown, len: 49 aa; similar to the extreme C-terminus of Moraxella catarrhalis TR:O85087 (EMBL:AF043131) hypothetical 60.4 kd protein (538 aa),fasta scores; E(): 2.6e-07, 34.7% identity in 49 aa overlap. Also similar to the C-terminus of NMA1678 (60.9% identity in 46 aa overlap), NMA0476 (43.5% identity in 46 aa overlap), and NMA2174 (33.3% identity in 48 aa overlap)
YP_002341690.1	NMA0139,  periplasmic protein, len: 85 aa; contains N-terminal signal sequence
YP_002341691.1	NMA0140, unknown, len: 49 aa
YP_002341692.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_002341693.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_002341694.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_002341695.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_002341696.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_002341697.1	binds directly to 23S ribosomal RNA
YP_002341698.1	Modulates Rho-dependent transcription termination
YP_002341699.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_002341700.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002341701.1	NMA0150, probable ferredoxin, len: 83 aa; similar to e.g. FER_CHRVI fP00208 erredoxin (82 aa), fasta scores; E(): 1.7e-20, 70.5% identity in 78 aa overlap. Contains Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains, and PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature
YP_002341702.1	NMA0151,  DNA methylase, len: 189 aa; similar to hypothetical proteins containing methylase signatures e.g. YHHF_ECOLI P10120 (198 aa), fasta scores; E(): 3.1e-19, 38.2% identity in 186 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop), and PS00092 N-6 Adenine-specific DNA methylases signature
YP_002341703.1	NMA0153, unknown, len: 126 aa; similar to TR:Q51849 (EMBL:U39043) Pasteurella haemolytica hypothetical protein (100 aa), fasta scores; E(): 1.2e-05, 35.7% identity in 84 aa overlap. Contains Pfam match to entry PF01381 HTH_3,Helix-turn-helix
YP_002341704.1	NMA0154, probable integral membrane protein, len: 183 aa
YP_002341705.1	NMA0155, unknown, len: 231 aa
YP_002341706.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity
YP_002341707.1	NMA0157, unknown, len: 153 aa; some similarity to SMG_ECOLI P30853 SMG protein (157 aa), fasta scores; E(): 1.1e-05, 27.3% identity in 132 aa overlap
YP_002341708.1	NMA0158, dprA, DprA homolog, len: 395 aa; similar to SMF_HAEIN P43862 SMF protein (DNA processing chain A) thought to be involved in DNA uptake (373 aa), fasta scores; E(): 1.9e-29, 40.1% identity in 324 aa overlap, and to hypothetical proteins e.g. SMF_ECOLI P30852 SMF protein (374 aa), fasta scores; E(): 2.3e-27, 37.2% identity in 360 aa overlap
YP_002341709.1	NMA0159, probable two-component trancriptional regulator, len: 425 aa; similar to many e.g. NTRX_AZOCA Q04849 nitrogen assimilation regulatory protein NTRX (454 aa), fasta scores; E(): 4.5e-15, 34.9% identity in 458 aa overlap, and HYDG_ECOLI P14375 transcriptional regulatory protein HYDG (441 aa), fasta scores; E(): 1.6e-14, 29.0% identity in 448 aa overlap. Contains Pfam match to entry PF00072 response_reg, Response regulator receiver domain, and Pfam match to entry PF00158 sigma54, Sigma-54 transcription factors
YP_002341710.1	NMA0160, probable two-component sensor, len: 706 aa; similar to many e.g. NTRY_AZOCA Q04850 nitrogen regulation protein NTRY (EC 2.7.3.-) (771 aa), fasta scores; E(): 0, 29.8% identity in 721 aa overlap, and ATOS_ECOLI Q06067 sensor protein ATOS (EC 2.7.3.-) (608 aa), fasta scores; E(): 2.4e-16, 25.3% identity in 439 aa overlap. Contains Pfam match to entry PF00672 DUF5, Domain found in bacterial signal proteins and Pfam match to entry PF00512 signal, Signal carboxyl-terminal domain, and four transmembrane domains
YP_002341711.1	NMA0161, unknown, len: 199 aa
YP_002341712.1	NMA0162, SUN homolog, len: 419 aa; similar to many e.g. SUN_ECOLI P36929 SUN protein (FMU protein) (429 aa),fasta scores; E(): 0, 41.2% identity in 427 aa overlap. Contains Pfam match to entry PF01189 Nol1_Nop2_Sun,NOL1/NOP2/sun family. Also similar to NMA1563 (29.9% identity in 371 aa overlap)
YP_002341713.1	NMA0163, fmt, methionyl-tRNA formyltransferase,len: 308 aa; similar to many e.g. FMT_ECOLI P23882 methionyl-tRNA formyltransferase (EC 2.1.2.9) (314 aa),fasta scores; E(): 0, 51.5% identity in 303 aa overlap. Contains Pfam match to entry PF00551 formyl_transf, Formyl transferase
YP_002341714.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_002341715.1	NMA0165, probable periplasmic protein, len: 405 aa; has short segment of similarity (encompassing PFAM domain) to TR:O51302 (EMBL:AE001138) Borrelia burgdorferi hypothetical 44.2 kd protein BB0323 (377 aa), fasta scores; E(): 0.0006, 46.0% identity in 50 aa overlap, and XKDP_BACSU P54335 phage-like element PBSX protein XKDP (235 aa), fasta scores; E(): 0.0083, 50.0% identity in 40 aa overlap. Contains Pfam match to entry PF01476 PG_binding_2,  peptidoglycan binding domain and N-terminal signal sequence
YP_002341716.1	NMA0166, probable integral membrane protein, len: 211 aa; contains two membrane spanning domains near N-terminus
YP_002341717.1	involved in the allosteric regulation of aspartate carbamoyltransferase
YP_002341718.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_002341719.1	NMA0169, unknown, len: 280 aa; some similarity in C-terminus to hypothetical proteins e.g. TR:O07579 (EMBL:Y14082) Bacillus subtilis hypothetical 16.4 kd protein YHDJ (142 aa), fasta scores; E(): 4.6e-06, 29.9% identity in 134 aa overlap, and PHNO_ECOLI P16691 PHNO protein (144 aa), fasta scores; E(): 0.00012, 31.9% identity in 144 aa overlap. Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family
YP_002341720.1	NMA0170, probable lipoprotein, len: 52 aa; contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341721.1	NMA0171, unknown, len: 239 aa; similar in part to NMA1084 (54.7% identity in 53 aa overlap), and NMA1073 (40.4% identity in 104 aa overlap)
YP_002341722.1	NMA0171A,  integral membrane protein, len: 78 aa; contains two  transmembrane domains
YP_002341723.1	NMA0173, unknown, len: 373 aa; some similarity to TR:O53037 (EMBL:U68399) Haemophilus influenzae  haemocin processing protein hmcC (198 aa), fasta scores; E(): 2.6e-11, 35.5% identity in 141 aa overlap, and the trhe N-terminus of TR:O87239 (EMBL:AE001272) Lactococcus lactis plasmid pMRC01 predicted cytolysin B transport protein (708 aa), fasta scores; E(): 9.1e-05, 29.0% identity in 138 aa overlap. Also similar to NMA1066 (70.7% identity in 164 aa overlap), and NMA0767 (69.4% identity in 124 aa overlap). Frameshifted at (C)6 tract w.r.t NmC sequence. Coding sequence has been spliced to give intact translation
YP_002341724.1	NMA0174, probable integral membrane protein, len: 183 aa; contains multiple hydrophobic transmembrane domains
YP_002341725.1	NMA0177, pykA, pyruvate kinase, len: 490 aa; similar to many e.g. KPY2_ECOLI P14178 pyruvate kinase II (EC 2.7.1.40) (PK-2) (479 aa), fasta scores; E(): 0, 49.9% identity in 491 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase
YP_002341726.1	NMA0178, probable outer membrane protein, len: 464 aa; weak similarity to several e.g. TR:Q00754 (EMBL:Q00754) Haemophilus influenzae outer membrane protein P1 precursor (449 aa), fasta scores; E(): 1.2e-07,27.6% identity in 474 aa overlap, TR:O51857 (EMBL:AF006691) Pseudomonas putida plasmid pRE4 outer membrane protein IPBH (492 aa), fasta scores; E(): 1.3e-05, 22.6% identity in 487 aa overlap, and FADL_ECOLI P10384 long-chain fatty acid transport protein precursor (448 aa), fasta scores; E(): 0.00035, 25.2% identity in 428 aa overlap. Contains N-terminal signal sequence
YP_002341727.1	NMA0181, unknown, len: 65 aa
YP_002341728.1	NMA0182, probable lipoprotein, len: 338 aa. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341729.1	NMA0183, gltS, sodium/glutamate symport carrier protein, len: 404 aa; similar to many e.g. GLTS_ECOLI P19933 sodium/glutamate symport carrier protein (glutamate permease) (401 aa), fasta scores; E(): 0, 50.9% identity in 393 aa overlap
YP_002341730.1	NMA0184, unknown, len: 468 aa; some similarity to hypothetical proteins e.g. YBEQ_ECOLI P77234 hypothetical 37.3 kd protein in leuS-gltL intergenic region (327 aa),fasta scores E(): 8.4e-07, 29.6% identity in 301 aa overlap
YP_002341731.1	NMA0185, lipB, capsule polysaccharide modification protein, len: 419 aa; almost identical to LIPB_NEIME Q05014 capsule polysaccharide modification protein (419 aa), fasta scores; E(): 0, 99.8% identity in 419 aa overlap, and similar to e.g. KSS5_ECOLI P42218 capsule polysaccharide export protein KPSS (389 aa), fasta scores; E(): 0, 38.3% identity in 400 aa overlap
YP_002341732.1	NMA0186, lipA, capsule polysaccharide modification protein, len: 704 aa; almost identical to, but longer than, LIPA_NEIME Q05013 capsule polysaccharide modification protein (400 aa), fasta scores; E(): 0, 97.1% identity in 383 aa overlap, and similar to e.g. KSC5_ECOLI P42217 capsule polysaccharide export protein KPSC (675 aa), fasta scores; E(): 0, 48.9% identity in 687 aa overlap. Contains PS00214 Cytosolic fatty-acid binding proteins signature
YP_002341733.1	NMA0187, rfbC2, dTDP-4-dehydrorhamnose 3,5-epimerase, len: 184 aa; almost identical to TR:Q51155 (EMBL:L09189) N. meningitidis B1940 rfbC (333 aa), fasta scores; E(): 0, 94.5% identity in 181 aa overlap, and similar to many e.g. RFBC_NEIGO P37763 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) (328 aa), fasta scores; E(): 0, 83.5% identity in 176 aa overlap. Contains Pfam match to entry PF00908 dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. Also highly similar to rfbC, NMA0206 (98.3% identity in 181 aa overlap)
YP_002341734.1	NMA0188, rfbA2, glucose-1-phosphate thymidylyltransferase, len: 288 aa; almost identical to RFBA_NEIME P55255 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (288 aa), fasta scores; E(): 0, 99.3% identity in 288 aa overlap, and similar to many e.g. RFBA_NEIGO P37762 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (288 aa), fasta scores; E(): 0, 88.5% identity in 288 aa overlap. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Identical to rfbA, NMA0205
YP_002341735.1	NMA0189, rfbB2, dTDP-glucose 4,6-dehydratase, len: 341 aa; identical to TR:AAD23919 (EMBL:AF083467) N. meningitidis MA-1 dTDP-D-glucose 4,6-dehydratase (341 aa), and similar to e.g. RFBB_NEIGO P37761 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) (346 aa), fasta scores; E(): 0, 92.4% identity in 340 aa overlap. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family. Identical to rfbB, NMA0204
YP_002341736.1	NMA0190, galE2', truncated UDP-glucose 4-epimerase,len: 205 aa; almost identical to TR:Q51291 (EMBL:L20496) N. meningitidis MC58 truncated UDP-glucose 4-epimerase (galE2) (205 aa), fasta scores; E(): 0, 97.1% identity in 205 aa overlap, and similar to the N-terminus of many e.g. GALE_NEIGO Q05026 UDP-glucose 4-epimerase (EC 5.1.3.2) (338 aa), fasta scores; E(): 0, 87.9% identity in 206 aa overlap. Contains Pfam match to entry PF01370 Epimerase,NAD dependent epimerase/dehydratase family. Almost identical to the C-terminus of galE, NMA0203 (95.6% identity in 206 aa overlap)
YP_002341737.1	NMA0194,  transcriptional accessory protein, len: 757 aa; similar to hypothetical proteins e.g. YHGF_ECOLI P46837 hypothetical 85.1 kd protein in greB-feoA intergenic region (773 aa), fasta scores; E(): 0, 61.7% identity in 772 aa overlap, and to TEX_BORPE Q45388 transcriptional accessory protein TEX (791 aa), fasta scores; E(): 0, 60.4% identity in 770 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain
YP_002341738.1	NMA0195, ctrD, probable capsule polysaccharide export ATP-binding protein, len: 216 aa; almost identical to CTRD_NEIME P32016 capsule polysaccharide export ATP-binding protein (216 aa), fasta scores; E(): 0, 93.5% identity in 216 aa overlap, and similar to e.g. KST5_ECOLI P24586 polysialic acid transport ATP-binding protein KPST (224 aa), fasta scores; E(): 0, 42.3% identity in 215 aa overlap. Contains Pfam match to entry PF00005 ABC_tran,ABC transporter, PS00017 ATP/GTP-binding site motif A (P-loop), and PS00211 ABC transporters family signature
YP_002341739.1	NMA0196, ctrC, capsule polysaccharide export inner-membrane protein, len: 265 aa; highly similar to CTRC_NEIME P32015 capsule polysaccharide export inner-membrane protein CTRC (265 aa), fasta scores; E(): 0, 79.2% identity in 265 aa overlap, and similar to e.g. BEX2_HAEIN P19391 capsule polysaccharide export inner-membrane protein CTRC (265 aa), fasta scores; E(): 0, 67.2% identity in 265 aa overlap. Contains Pfam match to entry PF01061 ABC2_membrane, ABC-2 type transporter, and PS00890 ABC-2 type transport system integral membrane proteins signature
YP_002341740.1	NMA0197, ctrB, capsule polysaccharide export inner-membrane protein, len: 387 aa; highly similar to CTRB_NEIME P32014 capsule polysaccharide export inner-membrane protein CTRB (387 aa), fasta scores; E(): 0, 84.0% identity in 387 aa overlap, and similar to e.g. BEXC_HAEIN P22930 capsule polysaccharide export inner-membrane protein BEXC (377 aa), fasta scores; E(): 0, 58.6% identity in 379 aa overlap
YP_002341741.1	NMA0198, ctrA, capsule polysaccharide export outer membrane protein, len: 387 aa; almost identical to CTR2_NEIME P32758 capsule polysaccharide export outer membrane protein CTRA precursor (387 aa), fasta scores; E(): 0, 99.7% identity in 387 aa overlap, and similar to e.g. BEXD_HAEIN P22236 capsule polysaccharide export protein BEXD (394 aa), fasta scores; E(): 0, 53.8% identity in 385 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341742.1	NMA0199, sacA,  UDP-N-acetyl-D-glucosamine 2-epimerase, len: 372 aa; almost identical to TR:O68214 (EMBL:AF019760) N. meningitidis F8229 UDP-N-acetyl-D-glucosamine 2-epimerase (372 aa), fasta scores; E(): 0, 99.7% identity in 372 aa overlap, and similar to e.g. WECB_ECOLI P27828 UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (376 aa), fasta scores; E(): 0,58.2% identity in 373 aa overlap
YP_002341743.1	NMA0200, sacB,  capsule biosynthesis protein, len: 545 aa; almost identical to TR:O68215 (EMBL:AF019760) N. meningitidis F8229 SACB (545 aa), fasta scores; E(): 0, 99.4% identity in 545 aa overlap, and similar to hypothetical proteins e.g. TR:O06628 (EMBL:Z95618) hypothetical 60.3 kd protein Rv0806c (532 aa), fasta scores; E(): 0, 35.0% identity in 380 aa overlap
YP_002341744.1	NMA0201, sacC,  capsule biosynthesis protein, len: 247 aa; identical to TR:O68216 (EMBL:AF019760) N. meningitidis F8229 SACC, (247 aa)
YP_002341745.1	NMA0202, sacD,  capsule biosynthesis protein, len: 287 aa; identical to TR:O68217 (EMBL:AF019760) N. meningitidis F8229 SACD (287 aa)
YP_002341746.1	NMA0203, galE, UDP-glucose 4-epimerase, len: 339 aa; almost identical to GALE_NEIME Q59624 UDP-glucose 4-epimerase (EC 5.1.3.2) (339 aa), fasta scores; E(): 0,97.6% identity in 339 aa overlap, and similar toi many e.g. GALE_ECOLI P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) (338 aa), fasta scores; E(): 0, 56.3% identity in 336 aa overlap. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family. Also similar in C-terminus to galE2' NMA0190 (95.6% identity in 206 aa overlap)
YP_002341747.1	NMA0204, rfbB, dTDP-glucose 4,6-dehydratase, len: 341 aa; identical to TR:AAD23919 (EMBL:AF083467) N. meningitidis MA-1 dTDP-D-glucose 4,6-dehydratase (341 aa), and similar to e.g. RFBB_NEIGO P37761 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) (346 aa), fasta scores; E(): 0, 92.4% identity in 340 aa overlap. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family. Identical to rfbB2, NMA0189
YP_002341748.1	NMA0205, rfbA, glucose-1-phosphate thymidylyltransferase, len: 288 aa; almost identical to RFBA_NEIME P55255 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (288 aa), fasta scores; E(): 0, 99.3% identity in 288 aa overlap, and similar to many e.g. RFBA_NEIGO P37762 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (288 aa), fasta scores; E(): 0, 88.5% identity in 288 aa overlap. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Identical to rfbA2, NMA0188
YP_002341749.1	NMA0206, rfbC, dTDP-4-dehydrorhamnose 3,5-epimerase, len: 184 aa; almost identical to TR:Q51155 (EMBL:L09189) N. meningitidis B1940 rfbC (333 aa), fasta scores; E(): 0, 93.1% identity in 189 aa overlap, and similar to many e.g. RFBC_NEIGO P37763 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) (328 aa), fasta scores; E(): 0, 84.2% identity in 184 aa overlap. Contains Pfam match to entry PF00908 dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase
YP_002341750.1	NMA0207, probable integral membrane protein, len: 672 aa; similar to several hypothetical integral membrane proteins e.g. Y561_HAEIN P44016 hypothetical protein HI0561/560 (633 aa), fasta scores; E(): 0, 65.0% identity in 640 aa overlap
YP_002341751.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_002341752.1	NMA0210, unknown, len: 53 aa
YP_002341753.1	NMA0211,  DNA transport competence protein,len: 154 aa; region of similarity to SW:P39694 (CME1_BACSU) ComE a late competence operon protein from Bacillus subtilis (205 aa) fasta scores; E(): 6.2e-07,47.6% identity in 63 aa overlap. Almost identical to TR:CAB44958 (EMBL:AJ242837) ComEA protein (fragment) from Neisseria meningitidis serogroup A strain Z2491 (170 aa) fasta scores; E(): 0, 98.7% identity in 154 aa overlap. Contains Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif and membrane-spanning hydrophobic region. Identical to NMA0423, and almost identical to NMA1915 (98.7% identity in 154 aa overlap), and NMA2187 (98.7% identity in 154 aa overlap)
YP_002341754.1	NMA0213, dksA,  DnaK suppressor protein,len: 138 aa; similar to e.g. DKSA_ECOLI P18274 DNAK suppressor protein (151 aa), fasta scores; opt: 376 z-score: 466.7 E(): 1.2e-18, 44.4% identity in 124 aa overlap. Contains Pfam match to entry PF01258 zf_dskA_traR, Prokaryotic dksA/traR C4-type zinc finger
YP_002341755.1	NMA0215, proC, probable pyrroline-5-carboxylate reductase, len: 263 aa; similar to many e.g. PROC_HAEIN P00373 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (271 aa), fasta scores; E(): 4.8e-32, 39.3% identity in 267 aa overlap. Contains Pfam match to entry PF01089 P5CR, Delta 1-pyrroline-5-carboxylate reductase
YP_002341756.1	NMA0216, probable lipoprotein, len: 135 aa. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341757.1	NMA0217, unknown, len: 228 aa; similar to hypothetical proteins e.g. YPT5_PSEAE P24562 (230 aa),fasta scores; E(): 0, 51.5% identity in 227 aa overlap. Pfam match to entry PF01168 UPF0001, Uncharacterized protein family UPF0001
YP_002341758.1	NMA0218, pilT,  pilus retraction protein,len: 347 aa; almost identical to TR:O85741 (EMBL:AF074716) Neisseria meningitidis PILT (347 aa), fasta scores; E(): 0, 99.4% identity in 347 aa overlap, and similar to e.g. PILT_PSEAE P24559 twitching mobility protein (344 aa),fasta scores; E(): 0, 66.6% identity in 344 aa overlap. Contains Pfam match to entry PF00437 GSPII_E, Bacterial type II secretion system protein, PS00017 ATP/GTP-binding site motif A (P-loop), and PS00662 Bacterial type II secretion system protein E signature. Also similar to pilT2 NMA0979 (40.6% identity in 335 aa overlap), and pilU NMA0219 (33.7% identity in 335 aa overlap)
YP_002341759.1	NMA0219, pilU, pilT-like protein, len: 408 aa; almost identical to TR:Q06582 (EMBL:L11719) Neisseria gonorrhoeae twitching motility protein homolog (180 aa),fasta scores; E(): 0, 97.8% identity in 180 aa overlap, and similar to TR:Q51532 (EMBL:L27667) Pseudomonas aeruginosa PILU (382 aa), fasta scores; E(): 0, 44.3% identity in 368 aa overlap. Contains 2x Pfam match to entry PF00437 GSPII_E, Bacterial type II secretion system protein, and PS00017 ATP/GTP-binding site motif A (P-loop). Also similar to pilT2 NMA0979 (44.8% identity in 348 aa overlap) and pilT NMA0218 (33.7% identity in 335 aa overlap)
YP_002341760.1	NMA0220, probable integral membrane protein, len: 716 aa; simlar to several hypothetical proteins e.g. YCCS_HAEIN P44289 HI1680 (718 aa), fasta scores; E(): 0,48.2% identity in 709 aa overlap, and YCCS_ECOLI P75870 (720 aa), fasta scores; E(): 0, 36.2% identity in 704 aa overlap. Highly similar in part to YOR2_NEIGO O33369 (417 aa), fasta scores; E(): 0, 81.1% identity in 355 aa overlap. Contains two sets of six  transmembrane domains between aa 1-150 and aa 370-500
YP_002341761.1	NMA0221, probable transposase for IS1106, len: 335 aa; almost identical to many e.g. TR:CAB44967 (EMBL:AJ242841) N. meningitidis  transposase for IS1106A3 (335 aa), fasta scores; E(): 0, 97.0% identity in 335 aa overlap
YP_002341762.1	NMA0222, probable peptide transporter, len: 485 aa; simlar to hypothetical proteins e.g. YCLF_BACSU P94408 (492 aa), fasta scores; E(): 0, 38.6% identity in 484 aa overlap, and to DTPT_LACLA P36574 di-/tripeptide transporter (463 aa), fasta scores; E(): 0, 36.7% identity in 463 aa overlap. Contains Pfam match to entry PF00854 PTR2, Peptide transporter family, and PS01023 PTR2 family proton/oligopeptide symporters signature 2
YP_002341763.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_002341764.1	NMA0225,  lipoprotein, len: 300 aa; similar to hypothetical proteins e.g. YCHK_ECOLI (314 aa), fasta scores; E(): 1.2e-17, 36.6% identity in 194 aa overlap. Contains Pfam match to entry PF01173 UPF0028,Uncharacterized protein family UPF0028, N-terminal signal sequence, and PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341765.1	NMA0226, probable integral membrane protein, len: 149 aa; similar to YG02_HAEIN P44270 HI1602 (151 aa),fasta scores; E(): 1.5e-32, 58.8% identity in 136 aa overlap. Also similar to NMA2196 (34.1% identity in 129 aa overlap)
YP_002341766.1	NMA0227, probable periplasmic protein, len: 102 aa; similar to YG01_HAEIN P44269 HI1601 precursor (95 aa),fasta scores; E(): 3.9e-09, 48.0% identity in 100 aa overlap. Contains N-terminal signal sequence
YP_002341767.1	NMA0228, unknown, len: 280 aa; similar to YG00_HAEIN P44268 HI1600 (317 aa), fasta scores; E(): 0,66.0% identity in 294 aa overlap
YP_002341768.1	NMA0229, unknown, len: 248 aa; similar to YF99_HAEIN P44267 HI1599 (238 aa), fasta scores; E(): 1.3e-24, 36.1% identity in 227 aa overlap
YP_002341769.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_002341770.1	NMA0233, probable lipoprotein, len: 140 aa. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341771.1	NMA0237, unknown, len: 200 aa; similar to hypothetical proteins e.g. YRDC_ECOLI P45748 (190 aa),fasta scores; E(): 4.4e-20, 41.7% identity in 168 aa overlap. Contains Pfam match to entry PF01300 Sua5_yciO_yrdC, SUA5/yciO/yrdC family, PS01147 SUA5/yciO/yrdC family signature, and PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site
YP_002341772.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_002341773.1	NMA0239, unknowwn, len: 105 aa
YP_002341774.1	NMA0240, unknown, len: 203 aa; similar to hypothetical proteins e.g. YIGZ_ECOLI P27862 (205 aa),fasta scores; E(): 6.5e-16, 36.3% identity in 160 aa overlap. Contains Pfam match to entry PF01205 UPF0029,Uncharacterized protein family UPF0029, and PS00910 Uncharacterized protein family UPF0029 signature
YP_002341775.1	NMA0241, etfA, electron transfer flavoprotein alpha-subunit, len: 311 aa; highly similar to many e.g. ETFA_BRAJA P53573 electron transfer flavoprotein alpha-subunit (314 aa), fasta scores; E(): 0, 59.4% identity in 310 aa overlap, and ETFA_HUMAN P13804 electron transfer flavoprotein alpha-subunit (333 aa), fasta scores; E(): 0, 55.1% identity in 312 aa overlap. Contains Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit
YP_002341776.1	NMA0242, etfB, flaX, electron transfer flavoprotein beta-subunit, len: 249 aa; almost identical to TR:Q51129 (EMBL:U40862) N. meningitidis FLAX (249 aa), fasta scores; E(): 0,97.2% identity in 249 aa overlap, and highly similar to e.g. ETFB_BRAJA P53575 electron transfer flavoprotein beta-subunit (249 aa), fasta scores; E(): 0,62.7% identity in 249 aa overlap, and ETFB_HUMAN P38117 electron transfer flavoprotein beta-subunit (255 aa),fasta scores; E(): 0, 55.6% identity in 252 aa overlap. Contains Pfam match to entry PF01012 ETF_beta, Electron transfer flavoprotein beta subunit
YP_002341777.1	NMA0243, rfaC, lipopolysaccharide heptosyltransferase I, len: 322 aa; almost identical to TR:Q51122 (EMBL:U35454) N. meningitidis heptosyltransferase I (322 aa), fasta scores; E(): 0,97.8% identity in 322 aa overlap, and similar to e.g. RFAC_ECOLI P24173 lipopolysaccharide heptosyltransferase-1 (319 aa), fasta scores; E(): 0, 40.8% identity in 287 aa overlap. Contains Pfam match to entry PF01075 Heptosyltranf, Heptosyltransferase
YP_002341778.1	NMA0244, pncA, probable nicotinamidase, len: 211 aa; similar to e.g. PNCA_ECOLI P21369 pyrazinamidase/nicotinamidase [includes: pyrazinamidase (EC 3.5.1.-) (PZASE); nicotinamidase (EC 3.5.1.19) (nicotine deamidase)] (213 aa), fasta scores; E(): 7e-09,32.5% identity in 212 aa overlap
YP_002341779.1	NMA0245, unknown, len: 226 aa; similar to hypothetical proteins e.g. YAEB_ECOLI P28634 (235 aa),fasta scores; opt: 578 z-score: 695.1 E(): 2.3e-31 41.8% identity in 232 aa overlap
YP_002341780.1	NMA0246, gapC, glyceraldehyde 3-phosphate dehydrogenase C, len: 334 aa; highly similar to many e.g. G3P_CLOPA Q59309 glyceraldehyde 3-phosphate dehydrogenase (EC 1.1.1.2842) (334 aa), fasta scores; E(): 0, 75.9% identity in 328 aa overlap, and G3P3_ECOLI P33898 glyceraldehyde 3-phosphate dehydrogenase C (EC 1.1.1.2842) (332 aa), fasta scores; E(): 0, 57.1% identity in 331 aa overlap. Contains Pfam match to entry PF00044 gpdh,glyceraldehyde 3-phosphate dehydrogenases, and PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. Also similar to gapA, NMA0062 (50.7% identity in 341 aa overlap)
YP_002341781.1	This protein performs the mismatch recognition step during the DNA repair process
YP_002341782.1	NMA0248,  acetyltransferase, len: 163 aa; contains weak similarity to predicted acetyltransferases e.g. TR:Q50708 (EMBL:Z77165) M. tuberculosis ribosomal-protein-alanine acetyltransferase (158 aa),fasta scores; E(): 0.00045, 30.5% identity in 154 aa overlap. Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family
YP_002341783.1	NMA0249, probable periplasmic protein, len: 113 aa; contains probable N-terminal signal sequence and coiled-coil domain around aa 50
YP_002341784.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_002341785.1	NMA0251, probable periplasmic protein, len: 218 aa; some similarity to e.g. TR:O07474 (EMBL:U61158) Staphylococcus gallinarum GDMH protein involved in antibiotic gallidermin secretion (330 aa), fasta scores; E(): 1.5e-06, 29.5% identity in 129 aa overlap, and SANA_ECOLI P33017 SANA protein involved in the barrier function of the cell envelope (239 aa), fasta scores; E(): 0.00013, 23.6% identity in 212 aa overlap. Contains N-terminal signal sequence
YP_002341786.1	NMA0252, probable oxidoreductase, len: 117 aa; similar to YFGD_ECOLI P76569 hypothetical protein (119 aa), fasta scores; E(): 1.2e-23, 53.9% identity in 115 aa overlap, and to e.g. ARC2_ECOLI P52147 arsenate reductase (141 aa), fasta scores; E(): 8.3e-12, 35.9% identity in 117 aa overlap
YP_002341787.1	NMA0253, probable periplasmic thiredoxin, len: 160 aa; similar to e.g. TLPA_BRAJA P43221 thiol:disulfide interchange protein TLPA (221 aa), fasta scores; E(): 7.4e-08, 30.7% identity in 153 aa overlap
YP_002341788.1	NMA0254, ftsE, probable ABC transporter ATP-binding protein, len: 305 aa; similar to e.g. FTSE_ECOLI P10115 cell division ATP-binding protein FTSE (222 aa), fasta scores; E(): 0, 50.2% identity in 215 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter
YP_002341789.1	NMA0255, ftsX, probable ABC transporter integral membrane protein, len: 305 aa; similar to e.g. FTSX_ECOLI P10122 cell division protein FTSX (352 aa), fasta scores; E(): 2.6e-20, 29.5% identity in 288 aa overlap
YP_002341790.1	NMA0256, unknown, len: 82 aa; similar to hypothetical proteins e.g. YV22_SYNY3 P73055 SSR3122 (85 aa), fasta scores; E(): 1.5e-06, 35.7% identity in 84 aa overlap, and YRBA_ECOLI P43781 (84 aa), fasta scores; E(): 6e-06, 31.5% identity in 73 aa overlap
YP_002341791.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_002341792.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_002341793.1	NMA0259, probable transmembrane transport protein,len: 324 aa; similar to hypothetical membrane proteins e.g. YGJT_ECOLI P42601 (321 aa), fasta scores; E(): 0,55.5% identity in 301 aa overlap, and to TERC_ALCSP P18780 tellurium resistance protein TERC (346 aa), fasta scores; E(): 1.4e-11, 34.8% identity in 345 aa overlap
YP_002341794.1	NMA0260, probable integral membrane protein, len: 149 aa; similar to TR:O26032 (EMBL:AE000648) Helicabacter pylori HP1502 (145 aa), fasta scores; E(): 2.3e-09, 29.5% identity in 149 aa overlap
YP_002341795.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
YP_002341796.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_002341797.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
YP_002341798.1	NMA0264, pilE, fimbrial protein precursor (pilin),len: 170 aa; highly similar to e.g. FMM1_NEIME P05431 fimbrial protein precursor (pilin) (167 aa), fasta scores; E(): 0, 85.2% identity in 169 aa overlap. Contains Pfam match to entry PF00114 pilin, and PS00409 Prokaryotic N-terminal methylation site
YP_002341799.1	NMA0272, pilS8, pilin, partial CDS, len: 113 aa; highly similar to e.g. FMD3_NEIGO Q00046 fimbrial protein MS11-D3A precursor (L-pilin) (180 aa), fasta scores; E(): 1.3e-16, 63.0% identity in 81 aa overlap
YP_002341800.1	NMA0273, fbp, peptidyl-prolyl cis-trans isomerase,len: 109aa; almost identical to FKBP_NEIME P25138 FK506-binding protein (peptidyl-prolyl cis-trans isomerase) (PPIASE) (EC 5.2.1.8) (109 aa), fasta scores; E(): 0, 97.2% identity in 109 aa overlap. Contains Pfam match to entry PF00254 FKBP, FKBP-type peptidyl-prolyl cis-trans isomerases, PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1, and PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2. Also similar to NMA1756 (45.9% identity in 98 aa overlap)
YP_002341801.1	NMA0274,  glycerate dehydrogenase, len: 322 aa; similar to DHGY_METEX Q59516 glycerate dehydrogenase (EC 1.1.1.29) (313 aa), fasta scores; E(): 0, 47.8% identity in 316 aa overlap, and to e.g. SERA_RAT O08651 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (533 aa),fasta scores; E(): 2.4e-26, 31.4% identity in 322 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH,D-isomer specific 2-hydroxyacid dehydrogenases, PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2, and PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3
YP_002341802.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_002341803.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_002341804.1	NMA0277, probable lipoprotein, len: 172 aa. Contains N-terminal signal sequence, and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341805.1	NMA0279, probable membrane-bound lytic murein transglycosylase, len: 441 aa; similar to MLTA_ECOLI P46885 membrane-bound lytic murein transglycosylase A precursor (EC 3.2.1.-) (365 aa), fasta scores; E(): 1.4e-16, 27.7% identity in 441 aa overlap. Contains N-terminal signal sequence, and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341806.1	NMA0280, probable integral membrane protein, len: 279 aa; similar to hypothetical membrane proteins e.g. YCDN_ECOLI P75901 (276 aa), fasta scores; E(): 0, 51.5% identity in 274 aa overlap
YP_002341807.1	NMA0281, probable lipoprotein, len: 388 aa; similar to hypothetical proteins e.g. YCDO_ECOLI P75902 (375 aa),fasta scores; E(): 0, 62.8% identity in 360 aa overlap. Contains N-terminal signals sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341808.1	NMA0282,  periplasmic protein, len: 421 aa; similar to e.g. YCDB_ECOLI P31545 hypothetical lipoprotein (423 aa), fasta scores; E(): 0, 49.5% identity in 424 aa overlap. Contains  N-terminal signal sequence
YP_002341809.1	NMA0283, phnA, PhnA protein NMB_orthologue, len: 109 aa; similar to many e.g. PHNA_ECOLI P16680 PHNA protein (111 aa), fasta scores; E(): 4.7e-25, 68.2% identity in 110 aa overlap
YP_002341810.1	NMA0284, glmU, UDP-N-acetylglucosamine pyrophosphorylase, len: 456 aa; similar to amny e.g. GLMU_NEIGO Q50986 UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (456 aa), fasta scores; E(): 0, 91.7% identity in 456 aa overlap. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase, and 2x Pfam match to entry PF00132 hexapep,Bacterial transferase hexapeptide (four repeats)
YP_002341811.1	NMA0287, tbpA, probable thiamin-binding periplasmic protein, len: 333 aa; similar to e.g. TBPA_ECOLI P31550 thiamin-binding periplasmic protein precursor (327 aa),fasta scores; E(): 3.3e-21, 30.9% identity in 333 aa overlap. Contains N-terminal signal sequence
YP_002341812.1	NMA0288, probable integral membrane protein, len: 282 aa; similar to hypothetical integral membrane proteins e.g. YGGB_ECOLI P11666 (286 aa), fasta scores; E(): 7.2e-31, 34.3% identity in 268 aa overlap. Contains Pfam match to entry PF00924 UPF0003, Uncharacterized protein family UPF0003
YP_002341813.1	NMA0289, unknown, len: 161 aa; similar to hypothetical proteins e.g. YGAD_ENTAG P51967 (164 aa),fasta scores; E(): 3.4e-26, 55.9% identity in 152 aa overlap, and to the C-terminus of CINA_STRPN P54184 competence-damage protein (418 aa), fasta scores; E(): 7e-11, 37.1% identity in 151 aa overlap
YP_002341814.1	NMA0290, pilB, probable peptide methionine sulfoxide reductase, len: 522 aa; almost identical to PMSR_NEIGO P14930 peptide methionine sulfoxide reductase (521 aa), fasta scores; E(): 0, 88.0% identity in 527 aa overlap, and similar in C-terminus to e.g. PMSR_STRPN P35593 peptide methionine sulfoxide reductase (312 aa),fasta scores; E(): 4.9e-31, 51.7% identity in 317 aa overlap, and in N-terminus to e.g. THIO_STRCO P52230 thioredoxin (110 aa), blastp scores; Expect = 0.0028, 30% identity in 107 aa overlap
YP_002341815.1	NMA0291, pilA, ftsY, probable signal recognition particle protein, len: 421 aa; almost identical to PILA_NEIME O30391 probable signal recognition particle protein (421 aa), fasta scores; E(): 0, 97.9% identity in 421 aa overlap, and highly similar to e.g. FTSY_ECOLI P10121 cell division protein FTSY (497 aa), fasta scores; E(): 0, 47.6% identity in 412 aa overlap. Contains Pfam match to entry PF00448 SRP54, SRP54-type protein, PS00017 ATP/GTP-binding site motif A (P-loop), and PS00300 SRP54-type proteins GTP-binding domain signature
YP_002341816.1	NMA0292, unknown, len: aa; almost identical to TR:O33368 (EMBL:AJ002423) N. gonorrhoeae hypothetical 11.4 kd protein (94 aa), fasta scores; E(): 0, 96.8% identity in 94 aa overlap. Also similar to NMA0011, fasta scores; E(): 5.4e-19; 54.2% identity in 83 aa overlap
YP_002341817.1	NMA0293, pilC2, pilus-associated protein,pseudogene, len: 30 aa; N-terminus identical to the N-terminus of TR:O05925 (EMBL:Y13021) N. meningitidis FAM20 pilC2 (1048 aa). C-terminus highly similar to the C-terminus of TR:O05925 (EMBL:Y13021) N. meningitidis FAM20 pilC2 (6248 bp), fasta scores; E(): 0, 75.2% identity in 1036 aa overlap. Contains a (g)11 tract at aa 27 that, if variable, would allow translation as an intact CDS. Also similar to NMA0609, pilC1 (intact) (90% identity in 30 aa overlap and 82.8% identity in 1050 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Coding sequence has been spliced to give intact translation
YP_002341818.1	NMA0295, probable periplasmic protein, len: 1371 aa; some similarity to YTFN_ECOLI P39321 hypothetical 136.8 kd protein (1259 aa), fasta scores; E(): 2.2e-17,21.6% identity in 1403 aa overlap. Contains N-terminal signal sequence
YP_002341819.1	NMA0296, probable outer membrane protein, len: 615 aa; some similarity to e.g. YTFM_ECOLI P39320 hypothetical protein (577 aa), fasta scores; E(): 2.3e-20, 23.4% identity in 569 aa overlap, and to TR:P95359 (EMBL:U81959) N. gonorrhoeae outer membrane protein omp85 (792 aa),fasta scores; E(): 0.0031, 23.2% identity in 595 aa overlap
YP_002341820.1	involved in the import of serine and threonine coupled with the import of sodium
YP_002341821.1	NMA0299, probable periplasmic protein, len: 497 aa; contains N-terminal signal sequence
YP_002341822.1	NMA0300, probable integral membrane protein, len: 71 aa
YP_002341823.1	NMA0301, unknonwn, len: 71 aa
YP_002341824.1	catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis
YP_002341825.1	NMA0304, unknown, len: 266 aa; similar to hypothetical proteins e.g. TR:AAD42399 (EMBL:AF157493) Zymomonas mobilis hypothetical competence-damage protein ZM10ORF4 (253 aa), fasta scores; E(): 8.4e-12, 31.1% identity in 209 aa overlap, and weakly simar to the N-terminus of e.g. CINA_BACSU P46323  competence-damage protein (416 aa), fasta scores; E(): 0.00012, 25.6% identity in 254 aa overlap
YP_002341826.1	NMA0305, probable protease, len: 328 aa; similar to part of e.g. SPPA_SYNY3 P73689 protease IV homolog (610 aa), fasta scores; E(): 1.4e-14, 32.7% identity in 211 aa overlap, and SPPA_ECOLI P08395 protease IV (618 aa), fasta scores; E(): 2.5e-10, 29.2% identity in 271 aa overlap. Contains Pfam match to entry PF01343 Peptidase_U7,Peptidase family U7
YP_002341827.1	NMA0307, unknown, len: 124 aa; similar to upstream gene NMA0320 (45.6% identity in 125 aa overlap)
YP_002341829.1	NMA0308, unknown, len: 118 aa
YP_002341830.1	NMA0310, unknown, len: 114 aa
YP_002341831.1	NMA0311, unknown, len: 133 aa; similar to NMA2120 (32.8% identity in 128 aa overlap)
YP_002341832.1	NMA0314, unknown, len: 105 aa
YP_002341833.1	NMA0316, unknown, len 100 aa
YP_002341834.1	NMA0317, unknown, len: 89 aa
YP_002341835.1	NMA0318, unknown, len: 68 aa
YP_002341836.1	NMA0320, unknown, len: 123 aa. Similar to NMA0307 (45.6% identity in 125 aa overlap)
YP_002341837.1	NMA0321, unknown, len: 68 aa
YP_002341838.1	NMA0322, unknown, len: 53 aa
YP_002341839.1	NMA0323, unknown, len: 68 aa. Similar to NMA0024 (46.4% identity in 69 aa overlap)
YP_002341840.1	NMA0324, mafB, adhesin, len: 492 aa; almost identical to TR:AAD31039 (EMBL:AF142582) Neisseria gonorrhoeae MS11 adhesin MAFB (509 aa), fasta scores; E(): 0, 72.6% identity in 503 aa overlap, but varying in the C-terminus. An identical sequence to the C-terminus is present in NMA0319 (mafB'). NMA0319, NMA0315, NMA0313 and NMA0309 contain perfect direct repeats from this gene, and may represent alternative C-termini. Contains N-terminal signal sequence. Also similar to NMA2113 (31.4% identity in 500 aa overlap), and NMA0853 (33.5% identity in 376 aa overlap)
YP_002341841.1	NMA0325, mafA, adhesin, len: 320 aa; almost identical to TR:AAD31038 (EMBL:AF142582) Neisseria gonorrhoeae MS11 adhesin MAFA (320 aa), fastaa scores; E(): 0, 98.4% identity in 320 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341842.1	Catalyzes the phosphorylation of UMP to UDP
YP_002341843.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_002341844.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_002341845.1	NMA0329,  integral membrane protein, len: 69 aa
YP_002341846.1	NMA0330, unknown, len: 193 aa; similar to hypothetical proteins e.g. YGFA_HAEIN P44905 hypothetical protein HI0858 (187 aa), fasta scores; E(): 5e-11, 27.8% identity in 194 aa overlap, and to e.g. FTHC_HUMAN P49914 5-formyltetrahydrofolate cyclo-ligase (202 aa), fasta scores; E(): 6.7e-07, 24.1% identity in 191 aa overlap
YP_002341847.1	NMA0331, unknown, len: 196 aa; similar to hypothetical proteins e.g. TR:O54394 (EMBL:U81516) hypothetical 24.4 kd protein (216 aa), fasta scores; E(): 4.2e-19, 37.2% identity in 199 aa overlap
YP_002341848.1	malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate
YP_002341849.1	NMA0335,  adhesin component, len: 186 aa; similar to TR:P94741 (EMBL:D78153) Eikenella corrodens component protein of adhesin complex (226 aa), fasta scores; E(): 3.9e-08, 43.9% identity in 98 aa overlap
YP_002341850.1	NMA0336, unknown, len: 99 aa
YP_002341851.1	NMA0337, map, methionine aminopeptidase, len: 259 aa; similar to many e.g. AMPM_ECOLI P07906 methionine aminopeptidase (EC 3.4.11.18) (264 aa), fasta scores; E(): 0, 56.4% identity in 257 aa overlap. Contains Pfam match to entry PF00557 Peptidase_M24, metallopeptidase family M24, and PS00680 Methionine aminopeptidase subfamily 1 signature
YP_002341852.1	NMA0338, probable periplasmic protein, len: 197 aa; contains N-terminal signal sequence and P-,E-rich C-terminal region
YP_002341853.1	NMA0339, probable lipoprotein, len: 202 aa; similar to hypothetical proteins e.g. YRAP_ECOLI P45467 (191 aa),fasta scores; E(): 4.8e-14, 35.0% identity in 183 aa overlap, and to HLY2_ACTPL P46028 Actinobacillus pleuropneumoniae 21 KD hemolysin precursor (194 aa), fasta scores; E(): 9.2e-10, 32.3% identity in 164 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341854.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
YP_002341855.1	NMA0341, unknown, len: 115 aa; similar to hypothetical proteins e.g. YRAN_ECOLI P45465 (131 aa),fasta scores; E(): 7.4e-11, 37.7% identity in 114 aa overlap
YP_002341856.1	NMA0342, unknown, len: 291 aa; similar to many hypothetical proteins e.g. YRAL_ECOLI P45528 (286 aa),fasta scores; E(): 0, 44.4% identity in 284 aa overlap. Contains Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases
YP_002341857.1	NMA0343, cybB, probable cytochrome B561, len: 134 aa; similar to e.g. C561_ECOLI P08732 cytochrome B561 (176 aa), fasta scores; E(): 0.00015, 30.6% identity in 134 aa overlap
YP_002341858.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_002341859.1	NMA0346, probable ATP-binding protein, len: 349 aa; Also similar to NMA0935 (28.7% identity in 338 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002341860.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_002341861.1	NMA0348,  nuclease, len: 259 aa; similar to EXOA_BACSU P37454 exodeoxyribonuclease (252 aa), fasta scores; E(): 0, 39.0% identity in 251 aa overlap, and TR:Q51380 (EMBL:U38241) Pseudomonas aeruginosa catabolite repression control protein (259 aa), fasta scores; E(): 0,37.3% identity in 255 aa overlap, and APE1_HUMAN P27695 DNA-(apurinic or apyrimidinic site) lyase (317 aa), fasta scores; E(): 0, 35.8% identity in 254 aa overlap. Contains Pfam match to entry PF01260 AP_endonucleas1, AP endonuclease family 1, and PS00726 AP endonucleases family 1 signature 1. Also similar to NMA2086, xthA (29.5% identity in 268 aa overlap)
YP_002341862.1	NMA0349, probable integral membrane protein, len: 114 aa; contains three  transmembrane domain
YP_002341863.1	NMA0350, unknown, len: 176 aa
YP_002341864.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_002341865.1	NMA0353, probable integral membrane protein, len: 193 aa; some similarity to YF60_HAEIN P44253 hypothetical protein HI1560 (156 aa), fasta scores; E(): 0.0012, 28.1% identity in 128 aa overlap
YP_002341866.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_002341867.1	NMA0356,  transferase, len: 168 aa; similar to e.g. TR:Q43999 (EMBL:U07639) Alcaligenes eutrophus H16 autotrophic growth (aut) gene (164 aa), fasta scores; E(): 0, 59.4% identity in 160 aa overlap, and to C-terminus of RFAE_ECOLI P76658 ADP-heptose synthase (477 aa), fasta scores; E(): 1.4e-22, 50.4% identity in 137 aa overlap. Contains Pfam match to entry PF01467 Cytidylyltransf,Cytidylyltransferase
YP_002341868.1	activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins and catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_002341869.1	NMA0358, probable periplasmic protein, len: 274 aa. Contains N-terminal signal sequence and probable coiled-coil domain from approx aa 70-100
YP_002341870.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_002341871.1	NMA0362, unknown, len: 64 aa
YP_002341872.1	NMA0363, thiE, thiamin-phosphate pyrophosphorylase,len: 205 aa; THIE_ECOLI P30137 thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) (211 aa), fasta scores; E(): 1.3e-32, 52.1% identity in 188 aa overlap. Contains PS00012 Phosphopantetheine attachment site
YP_002341873.1	NMA0364, probable oxidoreductase, len: 366 aa; similar to e.g. TR:O34292 (EMBL:AF004408) Rhizobium etli amino acid oxidase flavoprotein thiO (327 aa),fasta scores; E(): 1.1e-23, 36.2% identity in 351 aa overlap, and GLOX_BACSU O31616 glycine oxidase (369 aa),fasta scores; E(): 1e-08, 24.3% identity in 350 aa overlap
YP_002341874.1	NMA0365, probable permease, len: 437 aa; similar to e.g. CODB_ECOLI P25525 cytosine permease (419 aa), fasta scores; E(): 3.8e-14, 26.0% identity in 369 aa overlap
YP_002341875.1	NMA0367, tldD, TLDD protein homolog, len: 480 aa; TLDD_ECOLI P46473 TLDD protein (481 aa), fasta scores; E(): 0, 53.9% identity in 477 aa overlap
YP_002341876.1	NMA0370, probable integral membrane protein, len: 462 aa; similar to hypothetical proteins e.g. Y325_HAEIN P44640 hypothetical protein HI0325 (450 aa), fasta scores; E(): 0, 49.8% identity in 464 aa overlap
YP_002341877.1	NMA0371, slyX, SLYX protein homolog, len: 74 aa; simlar to SLYX_HAEIN P44759 SLYX protein homolog (73 aa),fasta scores; E(): 0.0017, 33.8% identity in 74 aa overlap, and SLYX_ECOLI P30857 SLYX protein (72 aa), fasta scores; E(): 0.24, 32.4% identity in 68 aa overlap
YP_002341878.1	NMA0373, thiF, probable ThiF protein, len: 256 aa; similar to e.g. THIF_ECOLI P30138 THIF protein (251 aa),fasta scores; E(): 0, 43.1% identity in 246 aa overlap, and MOEB_ECOLI P12282 molybdopterin biosynthesis MOEB protein. (249 aa), fasta scores; E(): 0, 43.9% identity in 244 aa overlap (note that N.m. does not have NMB_orthologues of any other molybdopterin biosynthesis proteins). Contains Pfam match to entry PF00899 ThiF_family, ThiF family
YP_002341879.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
YP_002341880.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_002341881.1	NMA0376, unknown, len: 109 aa; contains several coiled-coil domains
YP_002341882.1	NMA0377, unknown, len: 101 aa; some similarity to YGFE_ECOLI P45580 (109 aa), fasta scores; E(): 0.00018,29.5% identity in 95 aa overlap
YP_002341883.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_002341884.1	forms a direct contact with the tRNA during translation
YP_002341885.1	NMA0381, metR, probable transcriptional activator protein METR, len: 309 aa; similar to METR_HAEIN P45349 transcriptional activator protein METR (309 aa), fasta scores; E(): 0, 68.4% identity in 304 aa overlap, and METR_ECOLI P19797 transcriptional activator protein METR (317 aa), fasta scores; E(): 0, 44.0% identity in 298 aa overlap. Contains Pfam match to entry PF00126 HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family, and PS00044 Bacterial regulatory proteins, lysR family signature
YP_002341886.1	NMA0382, unknown, len: 249 aa; similar to hypothetical proteins e.g. YBGI_HAEIN Q57354 hypothetical protein HI0105 (279 aa), fasta scores; E(): 0, 49.8% identity in 241 aa overlap
YP_002341887.1	NMA0383, petA, ubiquinol-cytochrome c reductase iron-sulfur subunit, len: 193 aa; similar to many e.g. UCRI_CHRVI O31214 ubiquinol-cytochrome c reductase iron-sulfur subunit (EC 1.10.2.2) (207 aa), fasta scores; E(): 0, 59.6% identity in 193 aa overlap. Contains Pfam match to entry PF00355 Rieske, Rieske iron-sulfur protein, and PS00200 Rieske iron-sulfur protein signature 2
YP_002341888.1	NMA0384, petB, cytochrome B, len: 449 aa; similar to many e.g. CYB_CHRVI O31215 Chromatium vinosum cytochrome B (EC 1.10.2.2) (411 aa), fasta scores; E(): 0,62.9% identity in 407 aa overlap. Contains Pfam match to entry PF00033 cytochrome_b_N, Cytochrome b(N-terminal)/b6/petB, Pfam match to entry PF00032 cytochrome_b_C, Cytochrome b(C-terminal)/b6/petD, and PS00192 Cytochrome b/b6 heme-ligand signature
YP_002341889.1	NMA0385, petC, cytochrome C1 precursor, len: 262 aa; similar to e.g. CY1_CHRVI O31216 cytochrome C1 precursor (244 aa), fasta scores; E(): 2.8e-27, 47.1% identity in 255 aa overlap. Contains PS00190 Cytochrome c family heme-binding site signature
YP_002341890.1	NMA0386, probable periplasmic protein, len: 594 aa; similar to YIGN_ECOLI P27850 hypothetical 54.7 kd protein (475 aa), fasta scores; E(): 0, 44.3% identity in 404 aa overlap. Contains N-terminal signal sequence and several coiled-coil domains in N-terminal half
YP_002341891.1	NMA0387,  hydrolase, len: 210 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YCBL_ECOLI P75849 (215 aa), fasta scores; E(): 0, 47.1% identity in 208 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily
YP_002341892.1	catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA
YP_002341893.1	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively
YP_002341894.1	NMA0390, probable sugar transport PTS system IIA component, len: 145 aa; simlar to e.g. PTFA_BACSU P26379 PTS system, fructose-specific IIA component (EC 2.7.1.69) (146 aa), fasta scores; E(): 0.053, 26.2% identity in 103 aa overlap, and the N-terminal domain of PTNA_ECOLI P08186 PTS system, mannose-specific IIAB component (322 aa),fasta scores; E(): 8.8e-06, 30.1% identity in 136 aa overlap
YP_002341895.1	NMA0391, ptsH, probable sugar transport PTS system phosphocarrier protein HPR, len: aa; similar to many e.g PTHP_ALCEU P23537 phosphocarrier protein HPR (89 aa),fasta scores; E(): 2.6e-17, 59.6% identity in 89 aa overlap. Contains Pfam match to entry PF00381 PTS-HPr, PTS HPr component phosphorylation sites, and PS00012 Phosphopantetheine attachment site
YP_002341896.1	NMA0392, ptsI, probable phosphoenolpyruvate-protein phosphotransferase (phosphotransferase system, enzyme I),len: aa; similar to many e.g. PT1_ALCEU P23536 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (592 aa), fasta scores; E(): 0, 46.1% identity in 583 aa overlap. Contains 2x Pfam match to entry PF00391 PEP-utilizers, PEP-utilizing enzymes, and PS00742 PEP-utilizing enzymes signature 2
YP_002341897.1	NMA0393, probable ABC-transport system ATP-binding protein, len: 312 aa; similar to e.g. POTA_ECOLI P23858 spermidine/putrescine transport atp-binding protein POTA (378 aa), fasta scores; E(): 0, 44.5% identity in 281 aa overlap. Contains Pfam match to entry PF00005 ABC_tran,ABC transporter, PS00017 ATP/GTP-binding site motif A (P-loop), and PS00211 ABC transporters family signature
YP_002341898.1	NMA0394, unknown, len:291 aa; some similarity to N-terminus of TNR3_SCHPO P41888 thiamine pyrophosphokinase (569 aa), fasta scores; E(): 4.7e-18, 30.4% identity in 260 aa overlap
YP_002341899.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_002341900.1	NMA0398, porB, porin, major outer membrane protein P.I, len: 329 aa; almost identical to many e.g. OMB2_NEIME P30688 major outer membrane protein P.IB precursor (331 aa), fasta scores; E(): 0, 94.9% identity in 331 aa overlap. Contains Pfam match to entry PF00267 Gram-ve_porins, General diffusion Gram-negative porins, and PS00576 General diffusion Gram-negative porins signature. Also similar to NMA1642, porA (43.7% identity in 398 aa overlap)
YP_002341901.1	NMA0400, chpA, PEMK-like protein, len: 105 aa; simlar to e.g. CHPA_ECOLI P33645 PEMK-like protein 1 (MAZF protein) (111 aa), fasta scores; E(): 7e-06, 38.9% identity in 72 aa overlap, and PEMK_ECOLI P13976 Plasmid IncFII R100 PEMK protein (133 aa), fasta scores; E(): 5.9e-05, 32.7% identity in 107 aa overlap
YP_002341902.1	NMA0401, unknonwn, len: 79 aa
YP_002341903.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_002341904.1	NMA0403, unknown, len: 230 aa; almost identical to TR:AAD38302 (EMBL:AF036242) N. meningitidis NMB hypothetical 26.3 kd protein (230 aa), fasta scores; E(): 0, 97.4% identity in 230 aa overlap, and similar to TR:O28566 (EMBL:AE000985) Archaeoglobus fulgidus AF1707 (219 aa), fasta scores; E(): 5.6e-06, 25.1% identity in 215 aa overlap. Also similar to NMA0032 (53.5% identity in 230 aa overlap)
YP_002341905.1	NMA0404, nlaB, probable 1-acyl-SN-glycerol-3-phosphate acyltransferase, len: 247 aa; identical to TR:AAD38301 (EMBL:AF036242) N. meningitidis NMB lysophosphatidic acid acyltransferase homolog (247 aa), and similar to many e.g. PLSC_BORBU Q59188 1-acyl-SN-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) (250 aa), fasta scores; E(): 4e-11, 31.4% identity in 226 aa overlap. Also similar to NMA1504, plsC (23.6% identity in 148 aa overlap). Contains N-terminal signal sequence
YP_002341906.1	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate
YP_002341907.1	NMA0408, probable integral membrane protein, len: 550 aa; highly similar to Y275_HAEIN P43975 hypothetical protein HI0275 (551 aa), fasta scores; E(): 0, 68.4% identity in 551 aa overlap
YP_002341908.1	NMA0409, probable amino-acid transport protein,len: 413 aa; similar to many e.g. MTR_ECOLI P22306 tryptophan-specific transport protein (414 aa), fasta scores; E(): 0, 47.1% identity in 408 aa overlap,TNAB_ECOLI P23173 low affinity tryptophan permease (415 aa), fasta scores; E(): 0, 43.5% identity in 409 aa overlap, and TYRP_ECOLI P18199 tyrosine-specific transport protein (403 aa), fasta scores; E(): 0, 36.9% identity in 401 aa overlap. Contains PS00594 Aromatic amino acids permeases signature
YP_002341909.1	Involved in ubiquinone biosynthesis
YP_002341910.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine
YP_002341911.1	NMA0412, probable glucokinase, len: 172 aa; similar to e.g. GNTK_SCHPO Q10242 probable gluconokinase (EC 2.7.1.12) (193 aa), fasta scores; E(): 1.8e-17, 41.5% identity in 176 aa overlap, GNTV_ECOLI P39208 thermosensitive gluconokinase (EC 2.7.1.12) (187 aa),fasta scores; E(): 2e-15, 41.8% identity in 134 aa overlap, and GNTK_ECOLI P46859 thermoresistant gluconokinase (EC 2.7.1.12) (175 aa), fasta scores; E(): 1.2e-16, 37.4% identity in 163 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002341912.1	NMA0413, gntP, probable gluconate permease, len: 461 aa; similar to many e.g. GNTP_BACSU Q9ZIJ1 gluconate permease (448 aa), fasta scores; E(): 0, 37.1% identity in 453 aa overlap
YP_002341913.1	NMA0414, probable permease, len: 530 aa; similar to many e.g. YABK_ECOLI P31549 (536 aa), fasta scores; E(): 1.1e-14, 28.0% identity in 517 aa overlap, and MODB_ECOLI P09834 molybdenum transport system permease (229 aa), fasta scores; E(): 9.1e-12, 29.8% identity in 198 aa overlap. Contains 2x Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, and PS00402 Binding-protein-dependent transport systems inner membrane comp sign
YP_002341914.1	NMA0415, unknown, len: 199 aa; similar to hypothetical proteins e.g. TR:O34872 (EMBL:AF008220) Bacillus subtilis YTIB (187 aa), fasta scores; E(): 0,55.4% identity in 184 aa overlap, and to CYNT_ECOLI P17582 carbonic anhydrase (EC 4.2.1.1) (219 aa), fasta scores; E(): 0.067, 31.5% identity in 108 aa overlap
YP_002341915.1	NMA0416, unknown, len: 197 aa; similar to many hypothetical proteins, e.g. YQEJ_BACSU P54455 (189 aa),fasta scores; E(): 1.7e-17, 35.5% identity in 203 aa overlap
YP_002341916.1	NMA0417, unknown, len: 128 aa; similar to many hypothetical proteins, e.g. YBEB_ECOLI P05848 (105 aa),fasta scores; E(): 3e-10, 36.4% identity in 110 aa overlap
YP_002341917.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_002341918.1	NMA0419, unknown, len: 88 aa; similar to many hypothetical proteins, e.g. YGGX_ECOLI P52065 (90 aa),fasta scores; E(): 8.2e-15, 44.3% identity in 88 aa overlap. Contains GC(6) repeat near C-terminus
YP_002341919.1	NMA0420, probable integral membrane protein, len: 227 aa; similar to many hypothetical proteins, e.g. YCCA_ECOLI P06967 (219 aa), fasta scores; E(): 2.5e-18,36.7% identity in 215 aa overlap. Contains Pfam match to entry PF01027 UPF0005, Uncharacterized protein family
YP_002341920.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_002341921.1	NMA0422, probable psedouridine synthase, len: 220 aa; similar to hypothetical proteins e.g. Y042_HAEIN P43930 hypothetical protein HI0042 (224 aa), fasta scores; E(): 0, 51.9% identity in 214 aa overlap, and to ribosomal psedouridine synthases e.g. RLUA_ECOLI P39219 ribosomal large subunit pseudouridine synthase A (218 aa), fasta scores; E(): 9.3e-12, 33.5% identity in 182 aa overlap. Contains Pfam match to entry PF00849 YABO, Hypothetical yabO/yceC/sfhB family, and PS01129 Hypothetical yabO/yceC/sfhB family signature
YP_002341922.1	NMA0423,  DNA transport competence protein,len: 154 aa; region of similarity to SW:P39694 (CME1_BACSU) ComE a late competence operon protein from Bacillus subtilis (205 aa) fasta scores; E(): 6.2e-07,47.6% identity in 63 aa overlap. Almost identical to TR:CAB44958 (EMBL:AJ242837) ComEA protein (fragment) from Neisseria meningitidis serogroup A strain Z2491 (170 aa) fasta scores; E(): 0, 98.7% identity in 154 aa overlap. Contains Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif and membrane-spanning hydrophobic region. Identical to NMA0211, and almost identical to NMA1915 (98.7% identity in 154 aa overlap), and NMA2187 (98.7% identity in 154 aa overlap)
YP_002341923.1	NMA0424, probable pilin, len: 149 aa; similar to e.g. FMM1_NEIGO P02974 fimbrial protein precursor (pilin) (165 aa), fasta scores; E(): 0.00029, 24.7% identity in 154 aa overlap. Contains PS00409 Prokaryotic N-terminal methylation site
YP_002341924.1	NMA0425, unknown, len: 89 aa
YP_002341925.1	NMA0427, probable modification methylase (cytosine-specific DNA methylase), len: 351 aa; similar to many e.g. MTD2_HERAU P25265 modification methylase HgiDII (EC ) (354 aa), fasta scores; E(): 0, 39.7% identity in 345 aa overlap. Contains 2x Pfam match to entry PF00145 DNA_methylase, C-5 cytosine-specific DNA methylase
YP_002341926.1	NMA0428, conserved hypothetical protein, len: 560aa; similar to many of undefined function eg. SW:P25280 (YD3M_HERAU) hypothetical protein from Herpetosiphon aurantiacus (Herpetosiphon giganteus) (611 aa) fasta scores; E(): 2.6e-15, 30.1% identity in 369 aa overlap. Lies in a region of unusually low GC content. Also shows weak similarity to SW:P70754 (MUTL_AQUPY) DNA mismatch repair protein from Aquifex pyrophilus (426 aa) fasta scores; E(): 4.4, 26.4% identity in 292 aa overlap.
YP_002341927.1	NMA0429, vsr, patch repair protein, len: 140aa; similar to SW:P09184 (VSR_ECOLI) vsr, patch repair protein from Escherichia coli (156 aa) fasta scores; E(): 9.8e-21,39.3% identity in 122 aa overlap. Lies in a region of unusually low GC content.
YP_002341928.1	NMA0430,  DNA helicase, len: 1041aa; regions similar to many eg. SW:P43329 (HRPA_ECOLI) ATP-dependent helicase from Escherichia coli (1281 aa) fasta scores; E(): 0, 30.6% identity in 1035 aa overlap. Contains a direct degenerate repeat (408-473, 474-531) which is absent from homologues.
YP_002341929.1	NMA0431,  inner membrane protein, len: 424aa; contains  membrane-spanning hydrophobic regions. Lies in a region of unusually low GC content.
YP_002341930.1	NMA0432, hypothetical protein, len: 375aa
YP_002341931.1	NMA0433, hrpA', ATP-dependent DNA helicase, len: 495aa; similar to regions of many eg. SW:P43329 (HRPA_ECOLI) hrpA, ATP-dependent DNA helicase from Escherichia coli (1281 aa) fasta scores; E(): 0, 64.5% identity in 453 aa overlap. Contains Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002341932.1	NMA0434, hypothetical inner membrane protein, len: 469aa; similar to SW:P37019 (YADQ_ECOLI) hypothetical protein from Escherichia coli (436 aa) fasta scores; E(): 1e-18, 29.2% identity in 449 aa overlap. Contains membrane-spanning hydrophobic regions.
YP_002341933.1	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
YP_002341934.1	NMA0436, hypothetical inner membrane protein, len: 230aa; similar to many eg. SW:P33373 (YOHK_ECOLI) hypothetical protein from Escherichia coli (231 aa) fasta scores; E(): 4.3e-26, 39.0% identity in 218 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002341935.1	NMA0437, hypothetical inner membrane protein, len: 114aa; similar to many eg. SW:P39591 (YWBH_BACSU) hypothetical protein from Bacillus subtilis (128 aa) fasta scores; E(): 1.9e-07, 36.0% identity in 111 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002341936.1	NMA0439, hypothetical protein, len: 72aa
YP_002341937.1	NMA0440, hypothetical outer membrane protein, len: 280aa; C-terminal region similar to many eg. SW:P76190 (YDHO_ECOLI) hypothetical protein from Escherichia coli (271 aa) fasta scores; E(): 1.2e-18, 50.9% identity in 116 aa overlap, similar to NMA1645 fasta scores; E(): 2.4e-20,45.8% identity in 120 aa overlap and contains Pfam match to entry PF00877 NLPC_P60, NLP/P60 family, includes several lipoproteins. N-terminal region contains 4 x EQPVLP(V/I)NR(A/V)PARRAGNADELIG(N/S)AMGL(N/L) repeat.
YP_002341938.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
YP_002341939.1	NMA0442, hypothetical inner membrane protein, len: 484aa; similar to many proposed transporters eg. TR:P73368 (EMBL:D90905) proposed Mg2+ transporter from Synechocystis sp. (strain PCC 6803) (463 aa) fasta scores; E(): 0, 30.6% identity in 422 aa overlap. Contains two Pfam matches to entry PF00571 CBS, CBS domain.
YP_002341940.1	NMA0444, probable hydroxyacylglutathione hydrolase,len: 250aa; similar to many eg. SW:Q47677 (GLO2_ECOLI) probable hydroxyacylglutathione hydrolase from Escherichia coli (251 aa) fasta scores; E(): 2.6e-26, 37.5% identity in 259 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.
YP_002341941.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_002341942.1	NMA0447, glnB, nitrogen regulatory protein P-II 1,len: 112aa; similar to many eg. SW:P05826 (GLNB_ECOLI) glnB, nitrogen regulatory protein P-II 1 from Escherichia coli (112 aa) fasta scores; E(): 1.9e-31, 74.1% identity in 112 aa overlap. Contains Pfam match to entry PF00543 P-II, Nitrogen regulatory protein P-II; Prosite match to PS00496 P-II protein urydylation site and Prosite match to PS00638 P-II protein C-terminal region signature
YP_002341943.1	NMA0448, probable ABC transporter ATP-binding subunit, len: 252aa; similar to many probable transporters eg. TR:P94420 (EMBL:D50453) from Bacillus subtilis (252 aa) fasta scores; E(): 0, 46.4% identity in 250 aa overlap. Contains Pfam match to entry PF00005 ABC_tran,ABC transporter; Prosite match to PS00211 ABC transporters family signature and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002341944.1	NMA0449, hypothetical protein, len: 193aa
YP_002341945.1	NMA0450,  inner membrane transport protein,len: 315aa; similar to many transport proteins eg. SW:P37737 (FATC_VIBAN) anguibactin transport protein from Vibrio anguillarum (317 aa) fasta scores; E(): 9.2e-27,29.3% identity in 307 aa overlap. Contains Pfam match to entry PF01032 FecCD_family, FecCD transport family; Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site and  membrane-spanning hydrophobic regions.
YP_002341946.1	NMA0451,  inner membrane transport protein,len: 322aa; similar to many transport proteins eg. SW:P37738 (FATD_VIBAN) anguibactin transport protein from Vibrio anguillarum (314 aa) fasta scores; E(): 0, 38.1% identity in 310 aa overlap. Contains Pfam match to entry PF01032 FecCD_family, FecCD transport family and membrane-spanning hydrophobic regions.
YP_002341947.1	NMA0452, fetB, probable ferric enterobactin periplasmic binding protein, len: 321aa; similar to many eg. SW:P11460 (FATB_VIBAN) anguibactin binding protein from Vibrio anguillarum (322 aa) fasta scores; E(): 3.7e-22, 30.8% identity in 302 aa overlap and TR:AAD29611 (EMBL:AF115385)  ferric enterobactin periplasmic binding protein from Neisseria gonorrhoeae (323 aa) fasta scores; E(): 0, 96.3% identity in 323 aa overlap. Contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002341948.1	NMA0453, fetA, probable ferric enterobactin receptor, len: 714aa; similar to many eg. TR:AAD29612 (EMBL:AF115385) FetA, ferric enterobactin receptor from Neisseria gonorrhoeae (713 aa) fasta scores; E(): 0, 95.0% identity in 714 aa overlap. Contains two Prosite match to PS01156 TonB-dependent receptor proteins signature 2.
YP_002341949.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_002341950.1	NMA0455, hypothetical protein, len: 51aa
YP_002341951.1	NMA0456,  inner membrane protein, len: 143aa; contains  membrane-spanning hydrophobic regions.
YP_002341952.1	NMA0457, iga2, IgA-specific serine endopeptidase,len: 1449aa; similar to many eg. SW:P09790 (IGA_NEIGO) iga, IgA-specific serine endopeptidase from Neisseria gonorrhoeae (1532 aa) fasta scores; E(): 0, 28.8% identity in 1594 aa overlap. Contains Prosite match to PS00135 Serine proteases, trypsin family, serine active site. Also similar to NMA0905, iga (29.9% identity in 1339 aa overlap)
YP_002341953.1	NMA0458, transposase for insertion element IS1106A3, len: 370aa; similar to many eg. TR:CAB44967 (EMBL:AJ242841) transposase for insertion element IS1106A3 from Neisseria meningitidis serogroup A strain Z2491 (this strain) (335 aa) fasta scores; E(): 0, 84.6% identity in 370 aa overlap. Also similar to many others on this chromosome eg. NMA1115 (fasta scores; E(): 0, 85.7% identity in 370 aa overlap).
YP_002341954.1	NMA0459, hypothetical protein, len: 223aa; similar to TRNEW:AAD39623 (EMBL:AF069302) hypothetical protein from Pediococcus pentosaceus (231 aa) fasta scores; E(): 2.6e-27, 38.1% identity in 223 aa overlap.
YP_002341955.1	NMA0462, polA, DNA polymerase I, len: 938aa; similar to many eg. SW:P00582 (DPO1_ECOLI) polA, DNA polymerase I from Escherichia coli (928 aa) fasta scores; E(): 0, 52.5% identity in 946 aa overlap. Contains Pfam match to entry PF00476 DNA_pol_A, DNA polymerase family A; Pfam match to entry PF01367 5_3_exonuclease, 5'-3' exonuclease and Prosite match to PS00447 DNA polymerase family A signature.
YP_002341956.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_002341957.1	NMA0464, hypothetical protein, len: 139aa; similar to SW:P44078 (Y931_HAEIN) hypothetical protein from Haemophilus influenzae (161 aa) fasta scores; E(): 7.7e-13, 40.7% identity in 123 aa overlap.
YP_002341958.1	NMA0465, hypothetical inner membrane protein, len: 338aa; similar to SW:P45290 (YEIH_HAEIN) hypothetical protein from Haemophilus influenzae (338 aa) fasta scores; E(): 0, 93.2% identity in 338 aa overlap. Contains membrane-spanning hydrophobic regions. Lies in a region of unusually low GC content.
YP_002341959.1	defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly
YP_002341960.1	NMA0467,  lipoprotein, len: 56aa; similar to SW:P17323 (LPPL_PSEAE) lipopeptide from Pseudomonas aeruginosa (46 aa) fasta scores; E(): 1.2, 44.4% identity in 45 aa overlap. Contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002341961.1	NMA0468, lysA, diaminopimelate decarboxylase, len: 406aa; similar to many eg. SW:P19572 (DCDA_PSEAE) lysA,diaminopimelate decarboxylase from Pseudomonas aeruginosa (415 aa) fasta scores; E(): 0, 59.0% identity in 400 aa overlap. Contains Pfam match to entry PF00278 Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase and Prosite match to PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2.
YP_002341962.1	NMA0470,  sodium-dependent inner membrane transport protein, len: 511aa; similar to many eg. SW:P44849 (Y736_HAEIN) hypothetical sodium-dependent transporter (508 aa) fasta scores; E(): 0, 59.7% identity in 506 aa overlap. Contains  membrane-spanning hydrophobic regions; two Pfam matches to entry PF00209 SNF, Sodium:neurotransmitter symporter family and Prosite match to PS00610 Sodium:neurotransmitter symporter family signature 1.
YP_002341963.1	NMA0471, insertion element IS1016 transposase, len: 217 aa; similar to many eg. TR:Q48234 (EMBL:X59756) insertion sequence IS1016-V6 from Haemophilus influenzae (191 aa) fasta scores; E(): 0, 70.3% identity in 175 aa overlap. Also similar to many others on this chromosome eg. NMA2185 (fasta scores; E(): 0, 97.7% identity in 217 aa overlap).
YP_002341964.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_002341965.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_002341966.1	NMA0474, hpuB, haemoglobin-haptoglobin-utilization protein, len: 810aa; strongly similar to many eg. SW:P96949 (U73112) hpuB,haemoglobin-haptoglobin-utilization protein from Neisseria meningitidis strain DNM2 (810 aa) fasta scores; E(): 0,96.5% identity in 810 aa overlap. Contains Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region.
YP_002341967.1	NMA0475, hpuA, haemoglobin-haptoglobin-utilization protein, len: 357aa; similar to many eg. TR:P96948 (EMBL:U73112) hpuA, haemoglobin-haptoglobin-utilization protein from Neisseria meningitidis strain DNM2 (341 aa) fasta scores; E(): 0, 77.4% identity in 359 aa overlap.
YP_002341968.1	NMA0476, hypothetical periplasmic protein, len: 505aa; weakly similar to hypothetical proteins eg. TR:Q9ZF57 (EMBL:AF118122)  outer membrane protein from Neisseria meningitidis (488 aa) fasta scores; E(): 5e-16, 26.3% identity in 452 aa overlap
YP_002341969.1	NMA0477,  para-aminobenzoate synthase component I, len: 598aa; regions similar to many eg. SW:P05041 (PABB_ECOLI) para-aminobenzoate synthase component I from Escherichia coli (453 aa) fasta scores; E(): 8.5e-29, 41.2% identity in 284 aa overlap. Contains Pfam match to entry PF01063 aminotran_4, Aminotransferase class IV and
YP_002341970.1	NMA0478,  outer membrane peptidase, len: 1068aa; similar to many eg. similar to a group of proteins described as outer membrane antigens or peptidases egs. SW:P31631 (SSA1_PASHA) serotype-specific antigen I from Pasteurella haemolytica (932 aa) fasta scores; E(): 5.7e-22, 26.1% identity in 509 aa overlap and SW:P09489 (PRTS_SERMA) extracellular serine protease from Serratia marcescens (1045 aa) fasta scores; E(): 1.8e-10, 23.7% identity in 1074 aa overlap. Contains two Pfam matches to entry PF00082 Peptidase_S8, Subtilase family; and Prosite match to PS00138 Serine proteases, subtilase family,serine active site.
YP_002341971.1	NAD-linked
YP_002341972.1	NMA0481, unknown, len: 66 aa
YP_002341973.1	NMA0482, unknown, len: 129 aa
YP_002341974.1	NMA0483,  transcriptional regulator, len: 305aa; C-terminal region weakly similar to that of many eg. SW:Q00753 (MSMR_STRMU) msm operon regulatory protein from Streptococcus mutans (278 aa) fasta scores; E(): 9.4e-05, 30.2% identity in 96 aa overlap. Contains Pfam match to entry PF00165 HTH_2, Bacterial regulatory helix-turn-helix proteins, araC family and Prosite match to PS00041 Bacterial regulatory proteins, araC family signature.
YP_002341975.1	NMA0485, probable ABC transport ATP-binding subunit, len: 286aa; similar to many eg. TR:Q9Z402 (EMBL:AF106002) toluene tolerance protein from Pseudomonas putida (269 aa) fasta scores; E(): 0, 50.8% identity in 260 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter; Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop) and Prosite match to PS00211 ABC transporters family signature.
YP_002341976.1	NMA0486,  ABC transport inner membrane subunit, len: 258aa; similar to many eg. TR:Q9Z401 (EMBL:AF106002) toluene tolerance protein from Pseudomonas putida (265 aa) fasta scores; E(): 0, 51.0% identity in 255 aa overlap. Lies downstream from an  ABC transport ATP-binding subunit (NMA0485) and contains  membrane-spanning hydrophobic regions.
YP_002341977.1	NMA0487,  outer membrane transport protein,len: 164aa; similar to many eg. TR:Q9Z400 (EMBL:AF106002) toluene tolerance protein from Pseudomonas putida (161 aa) fasta scores; E(): 1.3e-19, 51.7% identity in 147 aa overlap. Appears to lie in an operon downstream of an  ABC transporter (NMA0485 and NMA0486). Contains Contains a cleavable N-terminal signal sequence and membrane-spanning hydrophobic regions.
YP_002341978.1	NMA0488,  periplasmic transport protein,len: 196aa; weakly similar to many eg. TR:Q9Z3Z9 (EMBL:AF106002) toluene tolerance protein from Pseudomonas putida (215 aa) fasta scores; E(): 0.0041, 24.2% identity in 211 aa overlap. Contains a  cleavable N-terminal signal sequence and appears to lie in a transport operon.
YP_002341979.1	NMA0489, hypothetical protein, len: 100aa; similar to SW:Q57407 (YA83_HAEIN) hypothetical protein from Haemophilus influenzae (105 aa) fasta scores; E(): 0.65,29.5% identity in 88 aa overlap.
YP_002341980.1	NMA0490,  periplasmic/outer membrane protein, len: 279aa; similar to many eg. SW:P43262 (VACJ_SHIFL) lipoprotein required for intercellular spreading of Shigella flexneri (251 aa) fasta scores; E(): 1.8e-14, 31.7% identity in 221 aa overlap. Seems to have a cleavable N-term signal seq.
YP_002341981.1	NMA0491, hypothetical protein, len: 160aa
YP_002341982.1	NMA0492, conserved hypothetical protein, len: 127aa; similar to many eg. SW:P77712 (YBAW_ECOLI) hypothetical protein from Escherichia coli (132 aa) fasta scores; E(): 3.1e-15, 40.2% identity in 127 aa overlap.
YP_002341983.1	NMA0493,  periplasmic protein, len: 162aa; similar to many of undefined function eg. TR:O66542 (EMBL:AE000675) from Aquifex aeolicus (146 aa) fasta scores; E(): 1.3e-06, 32.0% identity in 128 aa overlap. Contains a  cleavable N-terminal signal sequence.
YP_002341984.1	NMA0494,  acetyltransferase, len: 170aa; similar to many eg. SW:P07464 (THGA_ECOLI) thiogalactoside transacetylase from Escherichia coli (203 aa) fasta scores; E(): 6.3e-10, 32.1% identity in 140 aa overlap. Contains two Pfam match to entry PF00132 hexapep,Bacterial transferase hexapeptide (four repeats).
YP_002341985.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002341986.1	NMA0496, cad, cadmium resistance protein, len: 213aa; strongly similar to TR:O05469 (EMBL:U76550) cadD,cadmium resistance protein from Staphylococcus aureus (209 aa) fasta scores; E(): 0, 55.5% identity in 209 aa overlap. Lies in a region of unusually low GC content.
YP_002341987.1	NMA0497, probable inner membrane protein, len: 558aa; similar to many eg. TR:P76473 (EMBL:AE000315) hypothetical protein from Escherichia coli (550 aa) fasta scores; E(): 5.4e-05, 25.1% identity in 379 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002341988.1	NMA0498, regF, probable regulator of pilE expression, len: 201aa; similar to TR:O33374 (EMBL:X99693) regF, regulator of pilE expression from Neisseria gonorrhoeae (201 aa) fasta scores; E(): 0, 98.0% identity in 201 aa overlap and SW:P05838 (SSPA_ECOLI) stringent starvation protein A from Escherichia coli (211 aa) fasta scores; E(): 3.3e-32, 45.8% identity in 201 aa overlap. Also similar to many glutathione transferases eg. TR:O24595 (EMBL:Y12862) glutathione transferase from Zea mays (Maize) (224 aa) fasta scores; E(): 2.3e-13, 32.3% identity in 195 aa overlap. Contains Pfam match to entry PF00043 GST, Glutathione S-transferases.
YP_002341989.1	NMA0499, regG,  regulator of pilE expression, may act in concert with regF (NMA0498) len: 130aa; similar to TR:O33375 (EMBL:X99693) regG (FRAGMENT), regulator of pilE expression from Neisseria gonorrhoeae (65 aa) fasta scores; E(): 2.6e-25, 98.5% identity in 65 aa overlap and SW:P25663 (SSPB_ECOLI) stringent starvation protein B from Escherichia coli (165 aa) fasta scores; E(): 6.7e-17, 46.6% identity in 118 aa overlap.
YP_002341990.1	NMA0501, conserved hypothetical protein, len: 148aa; similar to many eg. TR:P71480 (EMBL:U63641) hypothetical protein from Legionella pneumophila (146 aa) fasta scores; E(): 1.3e-19, 46.3% identity in 147 aa overlap.
YP_002341991.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_002341992.1	NMA0503,  transglycosylase, len: 616aa; weakly similar to many eg. SW:P03810 (SLT_ECOLI) soluble lytic transglycosylase from Escherichia coli (645 aa) fasta scores; E(): 9.8e-21, 24.8% identity in 592 aa overlap. Contains Pfam match to entry PF01464 SLT,Transglycosylase SLT domain and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002341993.1	NMA0504, probable ABC transport ATP-binding subunit, len: 249aa; similar to many eg. SW:P30750 (ABC_ECOLI) ATP-binding protein ABC from Escherichia coli (343 aa) fasta scores; E(): 0, 50.6% identity in 243 aa overlap. Contains Pfam match to entry PF00005 ABC_tran,ABC transporter; Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop) and Prosite match to PS00211 ABC transporters family signature.
YP_002341994.1	NMA0505, probable inner membrane transport protein,len: 228aa; similar to many eg. SW:P31547 (YAEE_ECOLI) hypothetical ABC transporter permease from Escherichia coli (217 aa) fasta scores; E(): 7e-28, 43.1% identity in 209 aa overlap. Lies immediately downstream of a  ABC transport ATP-binding subunit and contains Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component.
YP_002341995.1	NMA0506,  lipoprotein, len: 287aa; similar to many eg. SW:P28635 (YAEC_ECOLI) hypothetical lipoprotein from Escherichia coli (271 aa) fasta scores; E(): 4.7e-27, 39.4% identity in 277 aa overlap. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002341996.1	NMA0507, probable decarboxylase, len: 189aa; similar to many eg. SW:P33751 (PAD1_YEAST) phenylacrylic acid decarboxylase from Saccharomyces cerevisiae (Baker's yeast) (242 aa) fasta scores; E(): 1e-30, 42.2% identity in 185 aa overlap.
YP_002341997.1	NMA0508,  chromosome segregation proteins,len: 286aa; similar to many eg. SW:P26497 (SP0J_BACSU) stage 0 sporulation protein from Bacillus subtilis (282 aa) fasta scores; E(): 0, 41.3% identity in 286 aa overlap. Contains helix-turn-helix motifs 132-153aa (+5.12 SD) and 143-164aa (+5.01 SD).
YP_002341998.1	NMA0510, hypothetical protein, len: 112aa; contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site and a  helix-turn-helix motif 32-53aa (+2.63 SD).
YP_002341999.1	NMA0511, insertion element IS1655 transposase, len: 254aa; similar to many eg. SW:P37247 (TRA4_BACFR) insertion element IS4351 transposase from Bacteroides fragilis (326 aa) fasta scores; E(): 3e-29, 38.5% identity in 252 aa overlap. Also similar to many others on this chromosome eg. NMA1486 (fasta scores; E(): 0, 100.0% identity in 254 aa overlap). Contains Pfam match to entry PF01460 Transposase_4, Transposase IS30 family. Contains helix-turn-helix motif 22-43aa (+4.99 SD).
YP_002342000.1	NMA0512, atpI, probable ATP synthase I, inner membrane protein, len: 117aa; weakly similar to many eg. SW:P03808 (ATPZ_ECOLI) atpI, probable ATP synthase I from Escherichia coli (125 aa) fasta scores; E(): 0.93, 25.5% identity in 102 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002342001.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_002342002.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_002342003.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_002342004.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_002342005.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_002342006.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_002342007.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_002342008.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_002342009.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002342010.1	NMA0522, hypothetical protein, len: 136aa; similar to SW:P44649 (YGGL_HAEIN) hypothetical protein from Haemophilus influenzae (114 aa) fasta scores; E(): 0.015,32.1% identity in 106 aa overlap.
YP_002342011.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002342012.1	NMA0524, lgtA, lacto-N-neotetraose biosynthesis glycosyl tranferase, len: 346 aa; highly similar to TR:Q51115 (EMBL:U25839), lgtA, Neisseria meningitidis lacto-N-neotetraose biosynthesis glycosyl tranferase (333 aa), fasta scores; E(): 0, 94.3% identity in 333 aa overlap. Contains Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferases
YP_002342013.1	NMA0525, lgtB, lacto-N-neotetraose biosynthesis glycosyl tranferase, len:279 aa; highly similar to SW:LGTB_NEIME (EMBL:U25839), lgtB, Neisseria meningitidis MC58 lacto-N-neotetraose biosynthesis glycosyl tranferase (275 aa), fasta scores; E(): 0, 92.5% identity in 279 aa overlap. Highly similar to NMA0527, fasta scores; E(): 0,75.7% identity in 280 aa overlap
YP_002342014.1	NMA0527, lgtB2, lacto-N-neotetraose biosynthesis glycosyl tranferase, len: 268 aa; highly similar to SW:LGTB_NEIME (EMBL:U25839), lgtB, Neisseria meningitidis MC58 lacto-N-neotetraose biosynthesis glycosyl tranferase (275 aa), fasta scores; E(): 0, 72.9% identity in 280 aa overlap. Highly similar to NMA0525, fasta scores; E(): 0,75.7% identity in 280 aa overlap
YP_002342015.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_002342016.1	NMA0529, len: 264 aa; unknown, similar to SW:SUHB_ECOLI (EMBL:M34828), suhB, Escherichia coli protein which affects sigma 32 synthesis (267 aa), fasta scores; E(): 4e-18, 34.8% identity in 184 aa overlap and to  homologues from other bacteria. Also similar to eukaryotic myo-inositol-1(or 4)-monophosphatases e.g. SW:MYOP_RAT (EMBL:U84038), impA1, Rattus norvegicus myo-inositol-1(or 4)-monophosphatase (277 aa), fasta scores; E(): 4.2e-17, 34.8% identity in 204 aa overlap. Also similar to NMA1559, fasta scores; E(): 5e-19, 35.2% identity in 179 aa overlap. Contains Pfam match to entry PF00459 inositol_P, Inositol monophosphatase family and PS00629 Inositol monophosphatase family signature 1
YP_002342017.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002342018.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_002342019.1	NMA0535, probable ABC transporter ATP-binding protein, len: 621 aa; similar to many e.g. SW:MSBA_ECOLI (EMBL:Z11796), msbA, Escherichia coli essential ABC transporter involved in lipid A and phospholipid biosynthesis (582 aa), fasta scores; E(): 0, 35.2% identity in 597 aa overlap. Contains Pfam matches to entry PF00664 ABC_membrane, ABC transporter transmembrane region and to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). Contains hydrophobic, probable membrane-spanning regions
YP_002342020.1	NMA0536, fabD, probable malonyl CoA-acyl carrier protein transacylase, len: 308 aa; similar to many e.g. SW:FABD_ECOLI (EMBL:M87040), fabD, Escherichia coli malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) (308 aa), fasta scores; E(): 0, 57.0% identity in 305 aa overlap. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain
YP_002342021.1	NMA0537,  integral membrane protein, len: 121 aa; unknown, in part similar to TR:P94519 (EMBL:Z75208), ysdA, Bacillus subtilis hypothetical protein (89 aa), fasta scores; E(): 3.1e-05, 39.3% identity in 84 aa overlap. Contains hydrophobic,  membrane-spanning regions
YP_002342022.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_002342023.1	NMA0540, len: 141 aa; unknown, lies within a region of unusually low GC content
YP_002342024.1	NMA0541, len: 83 aa, unknown, lies within a region of unusually low GC content
YP_002342025.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_002342026.1	NMA0543, len: 175 aa; shows very weak similarity to TR:P74916 (EMBL:D37928), gpt, Thermus aquaticus purine phosphoribosyltransferase (154 aa), fasta scores; E(): 8.7e-05, 27.8% identity in 158 aa overlap and to hypothetical proteins e.g. TR:CAB49024 (EMBL:AJ248283) purine phosphoribosyltransferase related protein (153 aa),fasta scores; E(): 2.5e-09, 30.1% identity in 163 aa overlap
YP_002342027.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_002342028.1	NMA0545, len: 167 aa; unknown, shows weak similarity to SW:YCED_ECOLI (EMBL:M29698), yceD,Escherichia coli hypothetical protein (17=3 aa), fasta scores; E(): 1.3e-07, 32.0% identity in 172 aa overlap and SW:YCED_HAEIN (EMBL:U20229), HI0159, Haemophilus influenzae hypothetical protein (174 aa), fasta scores; E(): 4.5e-06,30.6% identity in 173 aa overlap
YP_002342029.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002342030.1	NMA0547, len: 241 aa; unknown, similar to many hypothetical proteins e.g. SW:YRAL_ECOLI (EMBL:U18997),yraL, Escherichia coli hypothetical protein (286 aa),fasta scores; E(): 5.6e-14, 31.1% identity in 235 aa overlap. Also similar to NMA0342, fasta scores; E(): 1.6e-14, 30.4% identity in 217 aa overlap
YP_002342031.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_002342032.1	NMA0549, len: 96 aa; unknown, similar to hypothetical proteins found downstream of rnpA and elsewhere in many bacteria e.g. SW:YIDD_ECOLI (EMBL:M11056), yidD, Escherichia coli hypothetical protein (85 aa), fasta scores; E(): 3.1e-14, 52.9% identity in 68 aa overlap. Also similar to TR:Q44066 (EMBL:L36462), hlyA,Aeromonas hydrophila  haemolysin (85 aa), fasta scores; E(): 3.1e-14, 52.9% identity in 68 aa overlap. GC frameplot suggests a start codon overlapping the stop codon of rnpA. However, similarity to other sequences suggests a start codon at codon 24 or 28. The true position is therefore uncertain
YP_002342033.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_002342034.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_002342035.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_002342036.1	binds the polymerase to DNA and acts as a sliding clamp
YP_002342037.1	NMA0554,  transposase for IS1016, len: 197 aa; similar to many e.g. TR:Q48234 (EMBL:X59756) ORF from Haemophilus influenzae insertion sequence IS1016-V6 (191 aa), fasta scores; E(): 0, 69.7% identity in 175 aa overlap
YP_002342038.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_002342039.1	NMA0556,  periplasmic protein, len: 147 aa; unknown, contains a probable N-terminal signal sequence
YP_002342040.1	NMA0557, mlp, lipoprotein, len: 171 aa; highly similar to TR:Q51103 (EMBL:U16284), mlp, Neisseria meningitidis BNCV lipoprotein not expressed by Neisseria gonorrhoeae (171 aa), fasta scores; E(): 0, 97.1% identity in 171 aa overlap. Contains a probable N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342041.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_002342042.1	NMA0560, drg, probable type II restriction endonuclease, len: 263 aa; similar to SW:T2D1_STRPN (EMBL:M14340), dpnC, Streptococcus pneumoniae type II restriction endonuclease (254 aa), fasta scores; E(): 0,43.4% identity in 256 aa overlap. Highly similar to TR:AAD34293 (EMBL:AF091143), drg, Neisseria meningitidis BL2  endonuclease (254 aa), fasta scores; E(): 0,100.0% identity in 252 aa overlap. Lies within a region of unusually low GC content
YP_002342043.1	NMA0562, len: 293 aa; unknown, shows weak similarity, except at the N-terminus, to hypothetical proteins from bacteria and yeast e.g. SW:YGGG_ECOLI (EMBL:M32363), yggG, Escherichia coli hypothetical protein (252 aa), fasta scores; E(): 1.3e-07 23.4% identity in 256 aa overlap. The predicted start codon is uncertain; fasta similarities and GC frameplot suggest that the start codon would be at approx. codon 17 where a potential signal sequence and lipoprotein attachment site would then be predicted. As no candidate sites are present, the nearest upstream alternative has been used. Lies within a region of unusually low GC content
YP_002342044.1	NMA0564,  DNA-binding protein, len: 103 aa; unknown, similar to TR:Q57459 (EMBL:X75356) Coxiella burnetii plasmid QpH1 hypothetical protein (114 aa), fasta scores; E(): 3.5e-15, 49.0% identity in 96 aa overlap. Contains Pfam match to entry PF01381 HTH_3,Helix-turn-helix. Contains probable helix-turn-helix motif at aa 58-79 (Score 1781, +5.25 SD)
YP_002342045.1	NMA0565, len: 122 aa; unknown, similar to TR:Q45933 (EMBL:X85964) Coxiella burnetii plasmid QpDV hypothetical protein (121 aa), fasta scores; E(): 3.5e-14, 39.2% identity in 120 aa overlap
YP_002342046.1	NMA0569, secG, probable protein-export integral membrane protein, len: 116 aa; similar to SW:SECG_ECOLI (EMBL:D16463), secG, Escherichia coli protein-export membrane protein (110 aa), fasta scores; E(): 2.9e-09,38.6% identity in 101 aa overlap. Contains a probable N-terminal signal sequence and a hydrophobic, probable membrane-spanning region
YP_002342047.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_002342048.1	NMA0571, len: 175 aa; unknown, similar to hypothetical proteins from bacteria and eukaryotes e.g. SW:YKG9_YEAST (EMBL:X75780), YKL069W, Saccharomyces cerevisiae hypothetical protein (180 aa), fasta scores; E(): 1.3e-20, 37.7% identity in 167 aa overlap and SW:YEBR_ECOLI (EMBL:AE000277), yebR, Escherichia coli hypothetical protein (183 aa), fasta scores; E(): 1.4e-20,44.0% identity in 150 aa overlap
YP_002342049.1	NMA0572, probable protein-L-isoaspartate O-methyltransferase, len: 218 aa; similar to many e.g. SW:PIMT_ECOLI (EMBL:M63493), pcm, Escherichia coli protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) (207 aa), fasta scores; E(): 1.5e-17, 38.7% identity in 186 aa overlap. Contains Pfam match to entry PF01135 PCMT,Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
YP_002342050.1	NMA0573, len: 107 aa; unknown, shows weak similarity SW:GLPE_ECOLI (EMBL:M96795), glpE, Escherichia coli protein of unknown function (108 aa), fasta scores; E(): 4.6e-06, 31.8% identity in 85 aa overlap and to other hypothetical protein of similar length. Also shows weak similarity to the C-termini of longer hypothetical proteins e.g. TR:O05860 (EMBL:Z95120) Mycobacterium tuberculosis hypothetical protein (392 aa), fasta scores; E(): 8.9e-10, 39.0% identity in 100 aa overlap. Contains Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain
YP_002342051.1	NMA0575, probable ferric siderophore receptor protein, len: 725 aa; similar to many ferric siderophore receptors e.g. TR:AAD26430 (EMBL:AF135154), fauA,Bordetella pertussis FERRIC alcaligin siderophore receptor (734 aa), fasta scores; E(): 0, 33.1% identity in 721 aa overlap. Contains Pfam match to entry PF00593 TonB_boxC,TonB dependent receptor C-terminal region. Contains a probable N-terminal signal sequence
YP_002342052.1	NMA0576, len: 107 aa; unknown, shows weak similarity to TR:P96597 (EMBL:AB001488), ydbB, Bacillus subtilis hypothetical protein (113 aa), fasta scores; E(): 2.7e-05, 33.3% identity in 66 aa overlap
YP_002342053.1	NMA0577, fetB2, probable ferric enterobactin transporter binding protein, len: 321 aa; similar to TR:AAD29611 (EMBL:AF115385), fetB, Neisseria gonorrhoeae ferric enterobactin transporter periplasmic binding protein (323 aa), fasta scores; E(): 0, 50.6% identity in 314 aa overlap. Contains a probable N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Similar to NMA0452, fasta scores; E(): 0, 50.0% identity in 314 aa overlap
YP_002342054.1	NMA0578,  araC-family transcriptional regulator, len: 318 aa; shows similarity to known transcriptional regulators only at the C-terminus, in the helix-turn-helix region e.g. TR:O52834 (EMBL:AJ000061), alcR, Bordetella bronchiseptica regulator of alcaligin siderophore synthesis (303 aa), fasta scores; E(): 5.2e-06, 32.9% identity in 140 aa overlap. Contains a probable helix-turn-helix motif at aa 236-257 (Score 2068,+6.23 SD). Contains Pfam match to entry PF00165 HTH_2,Bacterial regulatory helix-turn-helix proteins, araC family
YP_002342055.1	NMA0579,  prolyl endopeptidase, len: 671 aa; shows weak similarity to known prolyl endopeptidases e.g. SW:PPCE_AERHY (EMBL:D14005) Aeromonas hydrophila prolyl endopeptidase (EC 3.4.21.26) (689 aa), fasta scores; E(): 3.5e-31, 25.5% identity in 666 aa overlap and SW:PPCF_FLAME (EMBL:M81461) Flavobacterium meningosepticum prolyl endopeptidase precursor (EC 3.4.21.26) (705 aa),fasta scores; E(): 1.8e-28, 24.7% identity in 684 aa overlap. Contains Pfam match to entry PF00326 Peptidase_S9, Prolyl oligopeptidase family
YP_002342056.1	catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis
YP_002342057.1	NMA0581, len: 144 aa; unknown
YP_002342058.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002342059.1	NMA0583, len: 245 aa; unknown
YP_002342060.1	NMA0584,  acetyltransferase, len: 146 aa; shows weak similarity to SW:RIMI_ECOLI (EMBL:X06117),rimI, Escherichia coli ribosomal-protein-alanine acetyltransferase (148 aa), fasta scores; E(): 1.4e-11,40.8% identity in 120 aa overlap. Also similar to hypothetical acetyltransferases. Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family
YP_002342061.1	NMA0585, len: 225 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YEAZ_ECOLI (EMBL:AE000275),yeaZ, Escherichia coli hypothetical protein (231 aa),fasta scores; E(): 6.7e-13, 35.2% identity in 227 aa overlap
YP_002342062.1	NMA0586,  lipoprotein, len: 280 aa; unknown, contains a  N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342063.1	class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis
YP_002342064.1	NMA0588, xerC, probable integrase/recombinase, len: 305 aa; similar to many e.g. SW:XERC_ECOLI (EMBL:M87049),xerC, Escherichia coli integrase/recombinase (298 aa),fasta scores; E(): 0, 43.7% identity in 300 aa overlap. Similar to NMA0964, fasta scores; E(): 4.4e-28, 35.0% identity in 294 aa overlap. Contains Pfam match to entry PF00589 Phage_integrase, 'Phage' integrase family
YP_002342065.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_002342066.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_002342067.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_002342068.1	3'-5' exoribonuclease specific for small oligoribonuclotides
YP_002342069.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_002342070.1	NMA0596, accC, probable acetyl-CoA carboxylase biotin carboxylase component, len: 453 aa; similar to many e.g. SW:ACCC_PSEAE (EMBL:L14612), accC, Pseudomonas aeruginosa biotin carboxylase (EC 6.3.4.14) (449 aa),fasta scores; E(): 0, 68.2% identity in 444 aa overlap. Contains Pfam match to entry PF00289 CPSase_L_chain,Carbamoyl-phosphate synthase (CPSase), PS00866 Carbamoyl-phosphate synthase subdomain signature 1 and PS00867 Carbamoyl-phosphate synthase subdomain signature 2
YP_002342071.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002342072.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_002342073.1	NMA0600, len: 192 aa; unknown, similar to SW:MDAB_ECOLI (EMBL:U18656), mdaB, Escherichia coli modulator of drug activity B ( modulator of topoisomerase IV activity imparting DMP 840, adriamycin and etoposide resistance on overexpression) (193 aa),fasta scores; E(): 0, 59.2% identity in 191 aa overlap. Also similar to hypothetical proteins from bacteria and Schizosaccharomyces pombe e.g. SW:YA05_SCHPO (EMBL:Z49811), SPAC5H10.05C, Schizosaccharomyces pombe hypothetical protein (196 aa), E(): 0, 55.7% identity in 192 aa overlap. Identical, except at the N-terminus, to NMA1174, fasta scores; E(): 0, 99.3% identity in 147 aa overlap
YP_002342074.1	NMA0601, probable lysR-family transcriptional regulator, len: 299 aa; similar to many e.g. TR:P72131 (EMBL:U35068), ptxR, Pseudomonas aeruginosa positive regulator of exotoxin A production (312 aa), fasta scores; E(): 7.4e-24, 31.9% identity in 295 aa overlap. Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family and PS00044 Bacterial regulatory proteins, lysR family signature. Contains probable helix-turn-helix motif at aa 19-40 (Score 1196, +3.26 SD)
YP_002342075.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_002342076.1	NMA0603, len: 182 aa; unknown, lies within a region of unusually low GC content. Shows weak similarity to NMA2217, fasta scores; E(): 4.4e-05, 23.8% identity in 185 aa overlap
YP_002342077.1	NMA0604, len: 187 aa; unknown, shows very weak similarity to the C-termini of SW:CMF3_BACSU (EMBL:Z18629), comFC, Bacillus subtilis competence protein (229 aa), fasta scores; E(): 0.077, 25.3% identity in 150 aa overlap and TR:AAD36651 (EMBL:AE001803), TM1584,Thermotoga maritima  competence protein (202 aa),fasta scores; E(): 0.003, 26.1% identity in 142 aa overlap. Lies within a region of unusually low GC content
YP_002342078.1	NMA0605, len: 129 aa; unknown, similar to ORFs present between the carA and carB genes of other Neisseria spp. e.g. TR:Q9ZIE8 (EMBL:AF029362) Neisseria gonorrhoeae ORF (129 aa), fasta scores; E(): 0, 91.5% identity in 129 aa overlap and to  CDS from other bacteria e.g. SW:YCJD_ECOLI (EMBL:AE000227), ycjD, Escherichia coli hop (117 aa), fasta scores; E(): 1.7e-20, 46.0% identity in 113 aa overlap
YP_002342079.1	NMA0606, len: 59 aa; unknown
YP_002342080.1	NMA0607, len: 45 aa; unknown, highly similar to part of TR:Q50992 (EMBL:L36381), sucA, Neisseria gonorrhoeae  2-oxoglutarate dehydrogenase E1 component (partial CDS) (582 aa), fasta scores; E(): 8.4e-17, 93.0% identity in 43 aa overlap. Up to codon 87 in TR:Q50992 the sequence is markedly different from other sucA homologues, including sucA from this strain
YP_002342081.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_002342082.1	NMA0609, pilC1, pilus-associated protein, len: 1037; highly similar to many other pilus-associated proteins from Neisseris spp. e.g. TR:O05924 (EMBL:Y13020),pilC1 from Neisseria meningitidis FAM20 (1038 aa), fasta scores; E(): 0, 78.0% identity in 1043 aa overlap. Contains 2 PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342083.1	NMA0611, len: 375 aa; unknown, similar to many hypothetical proteins from both bacteria and eukaryotes e.g. SW:MRP_ECOLI (EMBL:U00007), mrp, Escherichia coli hypothetical protein (379 aa), fasta scores; E(): 0, 45.2% identity in 372 aa overlap. Contains a region similar to NMA0076, fasta scores; E(): 1.2e-06, 24.1% identity in 266 aa overlap and NMA0100, fasta scores; E(): 2.4e-05, 26.3% identity in 262 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342084.1	NMA0612,  periplasmic thioredoxin, len: 169 aa; similar to many e.g. shows weak similarity to SW:CCMG_PARDE (EMBL:Z71971), ccmG, Paracoccus denitrificans periplasmic protein-disulfide oxidoreductase (179 aa), fasta scores; E(): 7e-05, 26.5% identity in 136 aa overlap and similar to SW:THIX_HAEIN (EMBL:U32791),HI1115, Haemophilus influenzae thioredoxin-like protein (167 aa), fasta scores; E(): 7.6e-26, 42.4% identity in 170 aa overlap. Contains a probable N-terminal signal sequence
YP_002342085.1	NMA0613, probable marR-family transcriptional regulator, len: 146 aa; shows weak similarity to TR:P94314 (EMBL:U64802), cinR, Butyrivibrio fibrisolvens transcriptional repressor of cinnamoyl ester hydrolase (142 aa), fasta scores; E(): 0.0013, 30.3% identity in 145 aa overlap and SW:HPCR_ECOLI (EMBL:S56952), hpaR,Escherichia coli homoprotocatechuate degradative operon repressor (148 aa), fasta scores; E(): 8.3e-26, 55.7% identity in 131 aa overlap. Contains Pfam match to entry PF01047 MarR, MarR family and PS01117 Bacterial regulatory proteins, marR family signature
YP_002342086.1	NMA0614, probable NADH:FMN oxidoreductase, len: 166 aa; similar to many NADH:FMN redox coupling protein components from multi-component monooxygenases e.g. TR:Q57501 (EMBL:Z37980), hpaC, Escherichia coli 4-hydroxyphenylacetate 3-monooxygenase coupling protein (170 aa), fasta scores; E(): 5.7e-24, 43.8% identity in 153 aa overlap and TR:O87008 (EMBL:U83405), tftC,Burkholderia cepacia chlorophenol-4-monooxygenase component 1 (179 aa), fasta scores; E(): 3.1e-15, 35.0% identity in 163 aa overlap
YP_002342087.1	NMA0615,  sugar-phosphate nucleotidyl transferase, len: 231 aa; Similar to the N-terminal regions of many e.g. TR:O08245 (EMBL:Y10907), mtmD,Streptomyces argillaceus TDP-D-glucose synthase (355 aa),fasta scores; E(): 4.2e-11, 30.7% identity in 241 aa overlap and SW:RFBA_XANCA (EMBL:L2394), rfbA, Xanthomonas campestris glucose-1-phosphate thymidylyltransferase involved in lipopolysaccharide biosynthesis (295 aa),fasta scores; E(): 9.1e-10, 31.7% identity in 240 aa overlap. Of a similar length to TR:AAD22456 (EMBL:AF116284) Pseudomonas aeruginosa hypothetical protein located downstream of a virulence factor (224 aa), fasta scores; E(): 0, 54.0% identity in 226 aa overlap. Similar to NMA0205, fasta scores; E(): 7.2e-09,27.9% identity in 247 aa overlap and NMA0188, fasta scores; E(): 7.2e-09, 27.9% identity in 247 aa overlap. Contains Pfam match to entry PF00483 NTP_transferase,Nucleotidyl transferase
YP_002342088.1	NMA0616, probable integral membrane protein, len: 143 aa; similar to bacterial hypothetical proteins e.g. SW:YCB6_PSEDE (EMBL:M62866) Pseudomonas denitrificans hypothetical protein (141 aa), fasta scores; E(): 1.4e-30,55.4% identity in 139 aa overlap. Contains Pfam match to entry PF00892 DUF6, Integral membrane protein. Contains hydrophobic, probable membrane-spanning regions
YP_002342089.1	catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate
YP_002342090.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_002342091.1	NMA0619,  lipopolysaccharide modification acyltransferase, len: 622 aa; similar to TR:P74874 (EMBL:U65941), oafA, Salmonella typhimurium integral membrane protein responsible for acetylation of the O-antigen (609 aa), fasta scores; E(): 0, 28.0% identity in 624 aa overlap and to TR:P72134 (EMBL:U50396), wbpC,Pseudomonas aeruginosa CDS involved in O-antigen (629 aa),fasta scores; E(): 0, 33.8% identity in 619 aa overlap. Also similar to several CDS from Caenorhabditis elegans e.g. TR:O02306 (EMBL:Z81147), T09E11.4, Caenorhabditis elegans hypothetical protein (650 aa), fasta scores; E(): 1.3e-24, 29.9% identity in 344 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342092.1	NMA0620, tyrS, probable tyrosyl-tRNA synthetase,len: 431 aa; similar to many e.g. SW:SYY_ECOLI (EMBL:J01719), tyrS, Escherichia coli tyrosyl-tRNA synthetase (EC 6.1.1.1) (423 aa), fasta scores; E(): 0,63.1% identity in 431 aa overlap. Contains Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y) and PS00178 Aminoacyl-transfer RNA synthetases class-I signature
YP_002342093.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_002342094.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_002342095.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_002342096.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_002342097.1	NMA0625,  phosphatase, len: 159 aa; shows weak similarity to phosphoglycolate phosphatases e.g. SW:GPHC_ALCEU (EMBL:M68904), cbbzC, Alcaligenes eutrophus chromosomal phosphoglycolate phosphatase (231 aa), fasta scores; E(): 6.5e-08, 30.2% identity in 172 aa overlap and SW:GPH_ECOLI (EMBL:Z19601), gph, Escherichia coli phosphoglycolate phosphatase (252 aa), fasta scores; E(): 4.2e-05, 23.1% identity in 173 aa overlap. The N-terminus may have been removed by insertion of the neighbouring IS element as this CDS appears to be shorter
YP_002342098.1	NMA0629, len: 108 aa; unknown
YP_002342099.1	NMA0630, len: 304 aa; unknown, shows weak similarity to TR:BAA80229 (EMBL:AP000061), APE1240,Aeropyrum pernix hypothetical protein (340 aa), fasta scores; E(): 0.00016, 27.1% identity in 266 aa overlap
YP_002342100.1	NMA0631, len: 1082 aa; unknown
YP_002342101.1	NMA0632, dnaE, probable DNA polymerase III, alpha subunit, len: 1144 aa; similar to many e.g. SW:DP3A_VIBCH (EMBL:U30472), dnaE, Vibrio cholerae DNA polymerase III,alpha subunit (EC 2.7.7.7) (1159 aa), fasta scores; E(): 0, 46.2% identity in 1170 aa overlap
YP_002342102.1	NMA0633, len: 77 aa; unknown, similar to SW:YBCJ_ECOLI (EMBL:D10588), ybcJ, Escherichia coli hypothetical protein (70 aa), fasta scores; E(): 7.7e-07,47.8% identity in 67 aa overlap and to the N-terminal half of TR:Q48692 (EMBL:X89367) Lactococcus lactis hypothetical protein (120 aa), fasta scores; E(): 5.4e-05, 43.9% identity in 66 aa overlap
YP_002342103.1	NMA0634, len: 71 aa; unknown
YP_002342104.1	NMA0635, len: 278 aa; unknown, similar to hypothetical proteins e.g. SW:YCIV_HAEIN (EMBL:U32820),HI1400, Haemophilus influenzae hypothetical protein (274 aa), fasta scores; E(): 0, 45.8% identity in 275 aa overlap and TR:Q9ZQI9 (EMBL:AC006218), F17L24.11,Arabidopsis thaliana hypothetical protein (312 aa), fasta scores; E(): 4.5e-20, 33.0% identity in 227 aa overlap
YP_002342105.1	transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis
YP_002342106.1	NMA0637, pglD, pilin glycosylation protein, len: 636 aa; highly similar to TR:AAC25981 (EMBL:AF014804) pglD from Neisseria meningitidis MC58 (636 aa), fasta scores; E(): 0, 96.7% identity in 636 aa overlap. Similar to many genes implicated in lipopolysaccharide biosynthesis e.g. TR:O05349 (EMBL:Y07788), rfbU, Vibrio cholerae mannosyl-transferase essential for O-antigen biosynthesis (621 aa), fasta scores; E(): 0, 47.7% identity in 616 aa overlap
YP_002342107.1	NMA0638, pglC, pilin glycosylation protein, len: 404 aa; highly similar to TR:AAC25980 (EMBL:AF014804) pglC from Neisseria meningitidis MC58 (391 aa), fasta scores; E(): 0, 95.1% identity in 391 aa overlap. Contains Pfam match to entry PF01041 DegT_DnrJ_EryC1,DegT/DnrJ/EryC1/StrS family
YP_002342108.1	NMA0639, pglB, pilin glycosylation protein, len: 413 aa; highly similar to TR:AAC25979 (EMBL:AF014804) pglB from Neisseria meningitidis MC58 (413 aa), fasta scores; E(): 0, 94.6% identity in 410 aa overlap. Possibly a transferase; N-terminal half is similar to the C-terminal half of e.g. SW:RFBP_SALTY (EMBL:X56793), rfbP, Salmonella typhimurium UDP-phosphate galactosephosphotransferase (476 aa), blastp scores; Expect = 1.5e-24. Contains an hydrophobic,  membrane-spanning region near the N-terminus. Contains Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats)
YP_002342109.1	NMA0640, len: 387 aa; unknown, shows very weak similarity to galactosyl transferases e.g. SW:RFAB_SALTY (EMBL:AF026386), rfaB, Salmonella typhimurium lipopolysaccharide 1,6-galactosyltransferase (359 aa),fasta scores; E(): 0.053, 25.3% identity in 324 aa overlap
YP_002342110.1	NMA0641,  glycosyl transferase, pseudogene,len: 1079 bp; shows weak similarity to the C-terminal half of many e.g. SW:CAPM_STAAU (EMBL:U10927), capM,Staphylococcus aureus type 1 capsular polysaccharide biosynthesis protein (380 aa), fasta scores; E(): 6.4e-09,26.8% identity in 190 aa overlap and TR:O84910 (EMBL:AF010183), wbpZ, Pseudomonas aeruginosa glycosyltransferase involved in A-band polysaccharide biosynthesis (381 aa), fasta scores; E(): 9e-07, 25.7% identity in 191 aa overlap. Also similar to NMA1057, fasta scores; E(): 1.3e-06, 28.7% identity in 129 aa overlap. Contains Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1. Contains a g{16} repeat which would allow this to be translated as an intact CDS,if variable
YP_002342111.1	NMA0643,  lipopolysaccharide biosynthesis translocase, len: 473 aa; shows weak similarity to several proteins implicated in lipopolysaccharide biosynthesis e.g. TR:Q56050 (EMBL:U40830), epsM, Streptococcus thermophilus eps cluster gene (473 aa), fasta scores; E(): 3.8e-10, 20.4% identity in 471 aa overlap and TR:Q56865 (EMBL:U46859), wzx, Yersinia enterocolitica  O-antigen 'flippase' (429 aa), fasta scores; E(): 3.2e-05,21.7% identity in 392 aa overlap. Contains hydrophobic,probable membrane-spanning regions
YP_002342112.1	NMA0644, ribD, probable diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase, len: 369 aa; similar to many e.g. SW:RIBD_ACTPL (EMBL:U27202),ribD, Actinobacillus pleuropneumoniae diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase (EC 3.5.4.26) (EC 1.1.1.193) (410 aa), fasta scores; E(): 0,42.4% identity in 323 aa overlap. Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342113.1	NMA0645, len: 154 aa; unknown, similar to many bacterial hypothetical proteins e.g. TR:O50470 (EMBL:AJ002783) Neisseria gonorrhoeae hypothetical protein (partial CDS) (109 aa), fasta scores; E(): 0, 93.5% identity in 108 aa overlap
YP_002342114.1	NMA0646, len: 280 aa; unknown, highly similar to TR:O50469 (EMBL:AJ002783), yafJ, Neisseria gonorrhoeae hypothetical protein (280 aa), fasta scores; E(): 0, 93.6% identity in 281 aa overlap and similar to SW:YAFJ_ECOLI (EMBL:D38582), yafJ, Escherichia coli hypothetical protein (255 aa), fasta scores; E(): 0, 51.8% identity in 255 aa overlap and to other bacterial hypothetical proteins
YP_002342115.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_002342116.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_002342117.1	NMA0650, pilQ, pilus secretin, len: 761 aa; highly similar to secretins from Neisseria spp. e.g. TR:Q9ZHF3 (EMBL:AF066056), pilQ, Neisseria meningitidis strain H44/76 (serogroup B) secretin precursor (766 aa), fasta scores; E(): 0, 84.9% identity in 766 aa overlap. Contains 5 copies of the small basic repeat PAKQQAAA (with slight degeneracy). Contains Pfam match to entry PF00263 Bac_GSPproteins, Bacterial type II secretion system protein and PS00875 Bacterial type II secretion system protein D signature. Contains a probable N-terminal signal sequence
YP_002342118.1	NMA0651, pilP, pilus assembly protein, len: 181 aa; highly similar to TR:Q50971 (EMBL:U40596), pilP, Neisseria gonorrhoeae type IV pilus biogenesis protein (180 aa),fasta scores; E(): 0, 96.7% identity in 181 aa overlap. Contains a probable N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342119.1	NMA0652, pilO, pilus assembly protein, len: 215 aa; highly similar to TR:Q50970 (EMBL:U40596), pilO, Neisseria gonorrhoeae type IV pilus biogenesis protein (215 aa),fasta scores; E(): 0, 98.6% identity in 215 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains an hydrophobic,  membrane-spanning region
YP_002342120.1	NMA0653, pilN, probable pilus assembly protein,len: 199 aa; similar to TR:Q52540 (EMBL:L28837), pilN,Pseudomonas syringae gene required for pilus expression (199 aa), fasta scores; E(): 1.5e-13, 27.9% identity in 197 aa overlap and highly similar to TR:O05129 (EMBL:U72876), pilN, Neisseria gonorrhoeae FA19 pilN (203 aa), fasta scores; E(): 0, 81.0% identity in 179 aa overlap (divergent at the C-terminus). Contains an hydrophobic,  membrane-spanning region
YP_002342121.1	NMA0654, pilM, probable pilus assembly protein,len: 371 aa; similar to TR:Q51351 (EMBL:U12892), pilM,Pseudomonas aeruginosa type 4 fimbrial assembly protein (354 aa), fasta scores; E(): 1.5e-17, 25.6% identity in 347 aa overlap and highly similar to TR:O05130 (EMBL:U72876), pilM, Neisseria gonorrhoeae FA19 pilM (371 aa), fasta scores; E(): 0, 94.6% identity in 371 aa overlap
YP_002342122.1	NMA0655, ponA, penicillin-binding protein 1, len: 798 aa; previously sequenced as TR:O05194 (EMBL:U80933) Neisseria meningitidis Z2491 penicillin-binding protein 1 (798 aa), fasta scores; E(): 0, 100.0% identity in 798 aa overlap. Contains Pfam matches to entry PF00912 Transglycosyl, Transglycosylase and to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain. Contains probable N-terminal signal sequence
YP_002342123.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_002342124.1	NMA0658, cyc, probable cytochrome C, len: 207 aa; similar to many e.g. SW:CYC4_PSEST (EMBL:U05988), cc4,Pseudomonas stutzeri cytochrome C4 precursor (210 aa),fasta scores; E(): 1e-19, 34.9% identity in 212 aa overlap. Contains two Pfam matches to entry PF00034 cytochrome_c, Cytochrome c and two PS00190 Cytochrome c family heme-binding site signature. Contains a probable N-terminal signal sequence
YP_002342125.1	NMA0659,  membrane protein, len: 650 aa; similar to TR:Q9ZG10 (EMBL:AF089765), resB, Thiobacillus ferrooxidans cytochrome C biosynthesis protein (591 aa), fasta scores; E(): 0, 32.0% identity in 659 aa overlap. Shows weak similarity to TR:O50041 (EMBL:U71000),ccs1, Chlamydomonas reinhardtii nuclear gene required for the post-translational assembly of chloroplast cytochrome C (613 aa), fasta scores; E(): 4.2e-05, 26.2% identity in 305 aa overlap. Contains a  N-terminal signal sequence and hydrophobic,  membrane-spanning regions
YP_002342126.1	NMA0660, probable membrane protein, len: 395 aa; similar to chloroplast genes required for cytochrome C biosynthesis e.g SW:CCSA_CHLRE (EMBL:U15556), ccsA,Chlamydomonas reinhardtii cytochrome C biogenesis protein (353 aa), fasta scores; E(): 1e-30, 36.1% identity in 266 aa overlap. Also similar to bacterial hypothetical proteins e.g. TR:Q9ZG09 (EMBL:AF089766), resC,Thiobacillus ferrooxidans  cytochrome C-type biogenesis protein (381 aa), fasta scores; E(): 0, 45.2% identity in 378 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342127.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_002342128.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
YP_002342129.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002342131.1	NMA0665, probable peptidase, len: 469 aa; similar to many e.g. TR:O85665 (EMBL:AF071224), pbp3, Neisseria gonorrhoeae penicillin binding protein 3 (469 aa), fasta scores; E(): 0, 96.6% identity in 469 aa overlap and SW:PBP4_ECOLI (EMBL:X59460), dacB, Escherichia coli penicillin-binding protein (477 aa), fasta scores; E(): 7.9e-21, 27.0% identity in 456 aa overlap. Contains probable N-terminal signal sequence
YP_002342132.1	NMA0666, probable oxidoreductase, len: 188 aa; similar to TR:AAD37373 (EMBL:AF145234), nqr, Arabidopsis thaliana NADPH:quinone oxidoreductase 9196 aa), fasta scores; E(): 2.9e-13, 35.7% identity in 168 aa overlap and to bacterial hypothetical proteins
YP_002342133.1	NMA0668, probable transmembrane transport protein,len: 437 aa; similar to e.g. SW:CITM_BACSU (EMBL:U62003),citM, Bacillus subtilis Mg2+/citrate complex secondary transporter (433 aa), fasta scores; E(): 0, 33.2% identity in 437 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342134.1	NMA0670,  two-component system sensor kinase, len: 416 aa; similar to several sensor kinases e.g. SW:IRLS_BURPS (EMBL:AF005358), irlS, Burkholderia pseudomallei sensor protein (464 aa), fasta scores; E(): 4.7e-16, 26.8% identity in 381 aa overlap. Also similar to SW:YGIY_ECOLI (EMBL:U28377), ygiY, Escherichia coli probable sensor protein (449 aa), fasta scores; E(): 8.7e-28, 31.6% identity in 335 aa overlap. Contains Pfam match to entry PF00512 signal, Signal carboxyl-terminal domain. Contains an hydrophobic,  membrane-spanning region
YP_002342135.1	NMA0672, len: 497 aa; unknown, similar to the N-terminal half of SW:RNE_ECOLI (EMBL:AE000209), rne,Escherichia coli ribonuclease E (1061 aa), fasta scores; E(): 0, 35.6% identity in 464 aa overlap and to SW:CAFA_ECOLI (EMBL:X57166), cafA, Escherichia coli cytoplasmic axial filament protein (488 aa), fasta scores; E(): 0, 49.5% identity in 491 aa overlap. Also similar to many bacterial hypothetical proteins. Similar to the N-terminal half of NMA0071 (rne), fasta scores; E(): 0,33.0% identity in 482 aa overlap
YP_002342136.1	NMA0673,  glutaredoxin, len: 85 aa; similar to many e.g. SW:GLR3_ECOLI (EMBL:U00039), grxC,Escherichia coli glutaredoxin 3 (82 aa), fasta scores; E(): 5.4e-11, 47.5% identity in 80 aa overlap. Contains PS00194 Thioredoxin family active site
YP_002342137.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
YP_002342138.1	catalyzes branch migration in Holliday junction intermediates
YP_002342139.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_002342140.1	NMA0677, len: 97 aa; unknown, contains a region similar to NMA0700, fasta scores; E(): 6.1e-09, 64.4% identity in 45 aa overlap
YP_002342141.1	NMA0680,  lipoprotein, len: 75 aa; unknown,contains a probable N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains one hydrophobic, membrane-spanning region. Lies within a region of unusually low GC content
YP_002342142.1	NMA0681, len: 117 aa; unknown
YP_002342143.1	NMA0684, len: 100 aa; unknown
YP_002342144.1	NMA0685, len: 56 aa; unknown
YP_002342145.1	NMA0687, probable periplasmic protein, len: 580 aa; similar to hemolysin activating proteins e.g. SW:HLYB_SERMA (EMBL:M22618), shlB, Serratia marcescens protein required for extracellular secretion and activation of hemoysin (557 aa), fasta scores; E(): 1.7e-07, 25.1% identity in 542 aa overlap and to SW:FHAC_BORPE (EMBL:X64876), fhaC, Bordetella pertussis hemolysin activator-like protein (584 aa), fasta scores; E(): 9.7e-08, 25.8% identity in 577 aa overlap. Contains a region identical to TR:P72090 (EMBL:U56747) Neisseria meningitidis strain Z2491 sequence found in Z2491 but not in Neisseria gonorrhoeae strain MS11, fasta scores; E(): 2.4e-23, 100.0% identity in 69 aa overlap. Contains a probable N-terminal signal sequence
YP_002342146.1	NMA0688, len: 2015 aa; similar to the N-terminal half of SW:FHAB_BORPE (EMBL:M60351), fhaB, Bordetella pertussis filamentous haemagglutinin (3591 aa), fasta scores; E(): 8.4e-25, 22.8% identity in 1884 aa overlap and to SW:HLYA_PROMI (EMBL:M30186), hmpA, Proteus mirabilis calcium-independent hemolysin (1577 aa), fasta scores; E(): 1.9e-09, 22.9% identity in 1692 aa overlap. Contains a region identical to TR:P72087 (EMBL:U56741) Neisseria meningitidis strain Z2491 sequence found in Z2491 but not in Neisseria gonorrhoeae strain MS11, fasta scores; E(): 2.3e-32, 100.0% identity in 117 aa overlap. The C-terminal region is highly similar to NMA0690, fasta scores; E(): 0, 70.6% identity in 571 aa overlap and NMA0962, fasta scores; E(): 0, 54.0% identity in 622 aa overlap. Also contains a sequence motif ILAYSKLVAGTVSGVVGGDVNTAANAAKVAIENNLL (codon 1629 to codon 1664) which occurs (with some degeneracy) within NMA0690,NMA0692 and NMA0695
YP_002342147.1	NMA0689, len: 127 aa; unknown, lies within a region of unusually low GC content
YP_002342148.1	NMA0690, len: 893 aa; unknown, highly similar to the C-terminal region of NMA0688, fasta scores; E(): 0,70.6% identity in 571 aa overlap and to NMA0992, fasta scores; E(): 0, 71.9% identity in 620 aa overlap. Also contains a sequence motif ILAYSKLVAGTVSGVVGGDVNAAANAAEVAVKNNQL (codon 540 to codon 575) which occurs (with some degeneracy) within NMA0688,NMA0692, and NMA0695. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342149.1	NMA0691, len: 143 aa; unknown, Asn-rich N-terminus,lies within a region of unusually low GC content
YP_002342150.1	NMA0692, len: 692 aa; unknown, contains an Ala-rich region from aa 330-400 approx. Highly similar to NMA0690,fasta scores; E(): 0, 71.9% identity in 620 aa overlap and to the C-terminal region of NMA0688, fasta scores; E(): 0,54.0% identity in 622 aa overlap. The Ala-rich region is not well conserved in NMA0690 and NMA0688. Also contains a sequence motif IAYSQIIAGSAVALVKGDVNTAVNAATVAVENNSL (codon 586 to codon 620) which occurs (with some degeneracy) within NMA0688, NMA0690, and NMA0695. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342151.1	NMA0693, len: 162 aa; unknown, lies within a region of unusually low GC content
YP_002342152.1	NMA0694, len: 90 aa; unknown, lies within a region of unusually low GC content
YP_002342153.1	NMA0695, len: 322 aa; unknown, contains an sequence motif ITAYSKLVAGTASAVVGGDVNTAANAAQIAVENNTL (codon 22 to codon 57) which occurs (with some degeneracy) at different positions within NMA0688, NMA0690 and NMA0692
YP_002342154.1	NMA0696, len: 311 aa; unknown
YP_002342155.1	NMA0696A, len: 311 aa; unknown
YP_002342156.1	NMA0697, len: 59 aa; unknown, lies within a region of unusually low GC content
YP_002342157.1	NMA0698,  periplasmic protein, len: 152 aa; unknown, contains a probable N-terminal signal sequence and lies within a region of unusually low GC content
YP_002342158.1	RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; this protein contains a C-terminal extension of unknown function
YP_002342159.1	NMA0702, len: 219 aa; similar to TR:Q52925 (EMBL:Z50189), exsB, Rhizobium meliloti  regulator of succinoglycan biosynthesis (not a transcriptional regulator) (234 aa), fasta scores; E(): 3.1e-15, 32.7% identity in 205 aa overlap. Also similar to many hbacterial ypothetical proteins e.g. SW:YBAX_HAEIN (EMBL:U32798), HI1191, Haemophilus influenzae hypothetical protein (196 aa), fasta scores; E(): 0, 79.2% identity in 173 aa overlap
YP_002342160.1	NMA0703, len: 172 aa; unknown
YP_002342161.1	NMA0704, len: 140 aa; similar to many hypothetical proteins e.g. SW:YB90_HAEIN (EMBL:U32798), HI1190,Haemophilus influenzae hypothetical protein (141 aa),fasta scores; E(): 5.1e-32, 58.0% identity in 138 aa overlap. Shows very weak similarity to eukaryotic 6-pyruvoyl-tetrahydropterin synthases e.g. SW:PTPS_RAT (EMBL:M77850), pts, Rattus norvegicus 6-pyruvoyl tetrahydrobiopterin synthase precursor (EC 4.6.1.10) (144 aa), fasta scores; E(): 0.0062, 27.3% identity in 154 aa overlap. Contains Pfam match to entry PF01242 PTPS,6-pyruvoyl tetrahydropterin synthase
YP_002342162.1	NMA0706,  membrane protein, len: 123 aa; similar to SW:YTRP_LACLA (EMBL:M87483) Lactococcus lactis (subsp. lactis) hypothetical protein (119 aa), fasta scores; E(): 9.2e-11, 39.7% identity in 116 aa overlap. Contains hydrophobic,  membrane-spanning regions
YP_002342163.1	NMA0707, len: 212 aa; similar to many bacterial hypothetical proteins e.g. SW:YGCF_HAEIN (EMBL:U32798),HI1189, Haemophilus influenzae hypothetical protein (211 aa), fasta scores; E(): 0, 61.4% identity in 202 aa overlap
YP_002342164.1	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
YP_002342165.1	NMA0709, probable integral membrane protein, len: 506 aa; similar to bacterial hypothetical proteins e.g. SW:YF86_HAEIN (EMBL:U32832), HI1586, Haemophilus influenzae hypothetical protein (519 aa), fasta scores; E(): 0, 60.7% identity in 507 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342166.1	NMA0710, probable periplasmic serine protease, len: 499 aa; similar to many e.g. TR:Q57155 (EMBL:U49151),mucD, Pseudomonas aeruginosa gene from locus affecting conversion to mucoidy in cystic fibrosis (474 aa), fasta scores; E(): 0, 49.8% identity in 454 aa overlap and SW:HTRA_ECOLI (EMBL:M36536), htrA, Escherichia coli protease DO precursor (EC 3.4.21.-) (474 aa), fasta scores; E(): 0, 33.5% identity in 457 aa overlap. Contains two Pfam matches to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF), Pfam match to entry PF00089 trypsin, Trypsin and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains a probable N-terminal signal sequence
YP_002342167.1	NMA0711, nth, probable endonuclease III, len: 209 aa; similar to many e.g. SW:END3_ECOLI (EMBL:J02857), nth,Escherichia coli endonuclease III (EC 4.2.99.18) (211 aa),fasta scores; E(): 0, 72.1% identity in 208 aa overlap. Contains Pfam match to entry PF00730 Endonuclease_3,Endonuclease III and PS01155 Endonuclease III family signature
YP_002342168.1	NMA0712,  membrane protein, len: 137 aa; similar to e.g. SW:YQAA_ECOLI (EMBL:AE000353), yqaA,Escherichia coli hypothetical protein (142 aa), fasta scores; E(): 1.1e-12, 34.8% identity in 141 aa overlap. Contains hydrophobic, membrane-spanning regions
YP_002342169.1	NMA0714, probable transmembrane hexose transporter,len: 407 aa; similar to sugar transporters e.g. SW:GLUP_BRUAB (EMBL:U43785), gluP, Brucella abortus glucose/galactose transporter (412 aa), fasta scores; E(): 0, 52.9% identity in 403 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains hydrophobic, probable membrane-spanning regions
YP_002342170.1	NMA0715, probable transmembrane transport protein,len: 459 aa; similar to SW:NHAC_BACFI (EMBL:U61539), nhaC,Bacillus firmus Na(+)/H(+) antiporter (462 aa), fasta scores; E(): 0, 36.5% identity in 446 aa overlap and to  transporters. Contains hydrophobic, probable membrane-spanning regions
YP_002342171.1	NMA0716, len: 274 aa; shows weak similarity to SW:HLYC_TREHY (EMBL:X73141), tlyC, Treponema hyodysenteriae hemolysin C (268 aa), fasta scores; E(): 7.4e-23, 33.7% identity in 252 aa overlap. Also similar to many hypothetical proteins e.g. SW:YBEX_ECOLI (EMBL:AE000170), ybeX, Escherichia coli hypothetical protein (292 aa), fasta scores; E(): 0, 51.1% identity in 266 aa overlap. Shows weak similarity to the C-terminal half of NMA1694, E(): 9.5e-17, 26.4% identity in 242 aa overlap. The  membrane-spanning regions of NMA1694 do not lie within this region. Contains two Pfam matches to entry PF00571 CBS, CBS domain
YP_002342172.1	NMA0717, len: 171 aa; similar to many bacterial hypothetical proteins e.g. SW:YBEY_ECOLI (EMBL:AE000170),ybeY, Escherichia coli hypothetical protein (155 aa),fasta scores; E(): 1.9e-24, 47.5% identity in 139 aa overlap
YP_002342173.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_002342174.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_002342175.1	NMA0720, len: 165 aa; unknown
YP_002342176.1	NMA0721, len: 67 aa; unknown
YP_002342177.1	NMA0722, probable transmembrane transport protein,len: 528 aa; shows weak similarity to lactate permeases e.g. SW:LLDP_ECOLI (EMBL:L13970), lldP, Escherichia coli L-lactate permease (551 aa), fasta scores; E(): 2.4e-29,25.3% identity in 550 aa overlap. Also similar to many hypothetical lactate permeases e.g. SW:YC18_HAEIN (EMBL:U32801), HI1218, Haemophilus influenzae  L-lactate permease (532 aa), fasta scores; E(): 0, 57.3% identity in 527 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342178.1	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine
YP_002342179.1	NMA0724, len: 1161 aa; unknown, contains two coiled-coil domains and shows weak similarity to many bacterial hypothetical proteins (also with coiled-coil domains) e.g. TR:O59462 (EMBL:AP000007), PH1798,Pyrococcus horikoshii hypothetical protein (1179 aa),fasta scores; E(): 0, 23.7% identity in 1217 aa overlap. Also shows weak similarity to coiled-coil-containing eukaryotic proteins involved in chromosome maintenance e.g. SW:XCPE_XENLA (EMBL:U13674), xcap-E, Xenopus laevis chromosome assembly protein (1203 aa), fasta scores; E(): 4.9e-16, 22.1% identity in 1198 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342180.1	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs
YP_002342181.1	NMA0726, probable pilin, len: 129 aa; similar to many type IV pilins e.g. TR:Q60148 (EMBL:L76605), pilE,Pseudomonas aeruginosa fimbrial protein precursor (141 aa), fasta scores; E(): 1.8e-09, 37.5% identity in 128 aa overlap and TR:AAD27895 (EMBL:AF027189), comF,Acinetobacter sp. BD413 pilin-like competence factor involved in natural transformation (141 aa), fasta scores; E(): 3.9e-07, 34.9% identity in 126 aa overlap. Similar to NMA0424, fasta scores; E(): 2e-11, 32.8% identity in 131 aa overlap, NMA1110, fasta scores; E(): 4.1e-07, 31.9% identity in 141 aa overlap and NMA0264, fasta scores; E(): 4.3e-07, 41.2% identity in 68 aa overlap. Contains PS00409 Prokaryotic N-terminal methylation site and a probable N-terminal signal sequence
YP_002342182.1	NMA0728, probable periplasmic protein, len: 392 aa; shows weak similarity to proteins encoding membrane transport functions e.g. SW:ACRA_ECOLI (EMBL:M94248),acrA, Escherichia coli acriflavin resistance protein (397 aa), fasta scores; E(): 1.3e-08, 26.9% identity in 338 aa overlap and SW:MTRC_NEIGO (EMBL:U14993), mtrC, Neisseria gonorrhoeae membrane fusion protein (412 aa), fasta scores; E(): 3.7e-07, 26.3% identity in 396 aa overlap. Contains probable N-terminal signal sequence
YP_002342183.1	NMA0729, probable ABC transporter ATP-binding protein, len: 644 aa; similar to many e.g. SW:YBJZ_ECOLI (EMBL:AE000189), ybjZ, Escherichia coli hypothetical ABC transporter ATP-binding protein (648 aa), fasta scores; E(): 0, 52.2% identity in 648 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). Contains hydrophobic, probable membrane-spanning regions
YP_002342184.1	NMA0730,  thiol:disulphide interchange protein, len: 260 aa; shows weak similarity to thiol:disulphide interchange proteins e.g. SW:DSBC_ECOLI (EMBL:M54884), dsbC, Escherichia coli thiol:disulfide interchange protein (236 aa), fasta scores; E(): 1.6e-13,27.7% identity in 231 aa overlap and SW:DSBC_ERWCH (EMBL:X76687), dsbC, Erwinia chrysanthemi thiol:disulfide interchange protein (238 aa), fasta scores; E(): 4.1e-11,24.5% identity in 220 aa overlap. Contains a probable N-terminal signal sequence. Cys 148 and Cys 151 are conserved in known thiol:disulphide interchange proteins
YP_002342185.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_002342186.1	NMA0732, probable integral membrane protein, len: 357 aa; unknown, contains hydrophobic, probable membrane-spanning regions
YP_002342187.1	NMA0733, probable transposase, len: 291 aa; similar to many e.g. similar to many e.g. TR:Q51474 (EMBL:M24471) Alteromonas atlantica CDS within insertion element IS492 which is involved in reversible inactivation of extracellular polysaccharide production (318 aa), fasta scores; E(): 1.6e-26, 34.8% identity in 267 aa overlap. Also shows weak similarity to pilin-inverting genes e.g. SW:PIV_MORLA (EMBL:M34367), piv, Moraxella acunata pilin gene inverting protein (322 aa), fasta scores; E(): 3.3e-11, 30.7% identity in 264 aa overlap. Highly similar to others from Neisseria meningitidis e.g. NMA1185, E(): 0, 94.3% identity in 279 aa overlap, also NMA2085. Contains Pfam match to entry PF01548 Transposase_9,Transposase
YP_002342188.1	NMA0734, probable transposase for IS1106A3, len: 316 aa; similar to many e.g. TR:CAB44967 (EMBL:AJ242841),Neisseria meningitidis transposase for insertion sequence IS1106A3 (335 aa), fasta scores; E(): 0, 97.2% identity in 282 aa overlap
YP_002342189.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_002342190.1	NMA0737, len: 90 aa; unknown
YP_002342191.1	NMA0738,  transcriptional regulator, len: 228 aa; shows weak similarity to phage repressors e.g. SW:RPC1_BPPH8 (EMBL:X13065) bacteriophage phi-80 repressor protein (235 aa), fasta scores; E(): 5.9e-11, 30.3% identity in 234 aa overlap. Also similar to other transcriptional regulators e.g. SW:PRTR_PSEAE (EMBL:D12706), prtR, Pseudomonas aeruginosa pyosin repressor protein (256 aa), fasta scores; E(): 2.5e-05,26.7% identity in 247 aa overlap. Similar to NMA1884,fasta scores; E(): 0, 53.4% identity in 232 aa overlap
YP_002342192.1	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors
YP_002342193.1	NMA0740, len: 154 aa; unknown
YP_002342194.1	an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions
YP_002342195.1	NMA0742, cysE, probable serine acetyltransferase,len: 272 aa; similar to many e.g. SW:CYSE_ECOLI (EMBL:M15745), cysE, Escherichia coli serine acetyltransferase (EC 2.3.1.30) (273 aa), fasta scores; E(): 0, 57.0% identity in 251 aa overlap. Contains Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) and PS00101 Hexapeptide-repeat containing-transferases signature
YP_002342196.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_002342197.1	NMA0745,  periplasmic protein, len: 71 aa; similar to SW:Y173_HAEIN (EMBL:U32702) Haemophilus influenzae hypothetical protein (86 aa), fasta scores; E(): 1.5e-10, 50.8% identity in 65 aa overlap. Contains a  N-terminal signal sequence
YP_002342198.1	NMA0746, apbE, probable thiamine biosynthesis protein, len: 351 aa; similar to e.g. SW:APBE_SALTY (EMBL:AF035376), apbE, Salmonella typhimurium thiamine biosynthesis lipoprotein apbE precursor (350 aa), fasta scores; E(): 0, 38.7% identity in 349 aa overlap. Contains a probable N-terminal signal sequence
YP_002342199.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_002342200.1	Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
YP_002342201.1	Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm
YP_002342202.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_002342203.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_002342204.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_002342205.1	NMA0753,  membrane protein, len: 473 aa; shows very weak similarity to SW:Y753_SYNY3 (EMBL:D90917) Synechocystis sp. (strain PCC 6803) hypothetical membrane protein (449 aa), fasta scores; E(): 1.7e-05, 23.9% identity in 481 aa overlap. Contains hydrophobic, membrane-spanning regions
YP_002342206.1	NMA0754,  membrane protein, len: 119 aa; similar to SW:YBAN_ECOLI (EMBL:AE000153), ybaN,Escherichia coli hypothetical protein, len: 125 aa, fasta scores; E(): 6.4e-17, 41.0% identity in 117 aa overlap and TR:Q51668 (EMBL:U34346) Paracoccus denitrificans hypothetical protein (fragment) (115 aa), fasta scores; E(): 8.5e-15, 36.5% identity in 115 aa overlap. Contains hydrophobic, membrane-spanning region
YP_002342207.1	NMA0755, len: 201 aa; unknown
YP_002342208.1	NMA0756, probable AsnC-family transcriptional regulator, len: 160 aa; similar to many e.g. SW:BKDR_PSEPU (EMBL:M57613), bkdR, Pseudomonas putida branched-chain keto acid dehydrogenase complex operon transcriptional regulator (161 aa), fasta scores; E(): 1.2e-23, 43.3% identity in 150 aa overlap. Contains Pfam match to entry PF01037 ASNC_trans_reg, AsnC family
YP_002342209.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_002342210.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_002342211.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_002342212.1	NMA0761,  regulatory protein, len: 173 aa; similar to the N-termini of several nosR proteins e.g. TR:O68483 (EMBL:AF047430), nosR, Sinorhizobium meliloti regulatory protein (755 aa), fasta scores; E(): 1.8e-12,38.3% identity in 115 aa overlap
YP_002342213.1	NMA0762, hypothetical protein, len: 344 aa; unknown function, similar to part of several nosD proteins e.g. SW:NOSD_PSEST (EMBL:X53676), nosD, Pseudomonas stutzeri copper-binding periplasmic protein precursor (436 aa),fasta scores; E(): 9.8e-29, 39.0% identity in 331 aa overlap
YP_002342214.1	NMA0763, probable ABC-transporter ATP-binding protein, len: 216 aa; similar to many ABC-transporter ATP-binding proteins e.g. SW:NOSF_PSEST (EMBL:X53676),nosF, Pseudomonas stutzeri copper transport ATP-binding protein (308 aa), fasta scores; E(): 5.2e-33, 50.5% identity in 200 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342215.1	NMA0765,  lipoprotein, len: 164 aa; similar to several nosL proteins e.g. TR:O07331 (EMBL:U94899),nosL, Sinorhizobium meliloti  outer-membrane lipoprotein (185 aa), fasta scores; E(): 2.4e-27, 45.1% identity in 164 aa overlap. Contains probable N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342216.1	NMA0766, probable electron transfer flavoprotein-ubiquinone oxidoreductase, len: 553 aa; similar to many eukaryotic enzymes e.g. SW:ETFD_HUMAN (EMBL:S69232), etfdH, Homo sapiens electron transfer flavoprotein-ubiquinone oxidoreductase precursor (EC 1.5.5.1) (617 aa), fasta scores; E(): 0, 56.6% identity in 558 aa overlap. Also shows weaker similarity to several bacterial fixC proteins e.g. SW:FIXC_AZOCA (EMBL:X55450),fixC, Azorhizobium caulinodans  electron transfer quinone reductase (435 aa), fasta scores; E(): 3.4e-11,24.6% identity in 398 aa overlap
YP_002342217.1	NMA0767, unknown, len: 138 aa; shows weak similarity to part of TR:O53037 (EMBL:U68399), hmcC,Haemophilus influenzae protein implicated in haemocin production (198 aa), fasta scores; E(): 1.1e-06, 30.9% identity in 110 aa overlap. Also highly similar to other proteins from Neisseria meningitidis, NMA0173, fasta scores; 70.7% identity in 164 aa overlap and NMA1066,fasta scores; 88.3% identity in 128 aa overlap
YP_002342218.1	NMA0768, probable transposase for IS1655, len: 321 aa; similar to many e.g. SW:TRA4_BACFR (EMBL:M17808) Bacteroides fragilis transposase for insertion sequence element (326 aa), fasta scores; E(): 0, 41.6% identity in 310 aa overlap. Contains Pfam match to entry PF01460 Transposase_4, Transposase IS30 family. Contains probable helix-turn-helix motif at aa 22-34 (Score 1705, +4.99 SD)
YP_002342219.1	NMA0769,  transposase for IS1016, len: 217 aa; similar to many e.g. TR:Q48234 (EMBL:X59756) ORF from Haemophilus influenzae insertion sequence IS1016-V6 (191 aa), fasta scores; E(): 0, 66.5% identity in 188 aa overlap
YP_002342220.1	NMA0772, probable DNA-invertase, len: 321 aa; similar to site-specific pilin-gene invertases from Moraxella e.g. SW:PIV_MORBO (EMBL:M32345), piv, Moraxella bovis pilin gene inverting protein (322 aa), fasta scores; E(): 2.8e-23, 30.0% identity in 320 aa overlap. Also similar to TR:P72078 (EMBL:U65994) Neisseria gonorrhoeae pilin gene inverting protein homolog (320 aa), fasta scores; E(): 0, 47.1% identity in 323 aa overlap. Similar to others from Neisseria meningitidis e.g. NMA1800 (318 aa), fasta scores; E(): 0, 40.9% identity in 318 aa overlap. Contains Pfam match to entry PF01548 Transposase_9, Transposase
YP_002342221.1	NMA0773, len: 82 aa; unknown
YP_002342222.1	NMA0774, unknown, len: 352 aa; similar to hypothetical proteins from bacteriophage and plasmids e.g. TR:O82966 (EMBL:AB015669) ORFC6 from Burkholderia solanacearum plasmid pJTPS1 (364 aa), fasta scores; E(): 9.7e-24, 30.9% identity in 366 aa overlap and TR:Q38198 (EMBL:M57538) unknown protein from bacteriophage Cf1c (388 aa), fasta scores; E(): 1.2e-16, 25.5% identity in 357 aa overlap. Similar to NMA1799, fasta scores; E(): 0, 40.4% identity in 369 aa overlap. Contains 2 PS00017 ATP/GTP-binding site motif A (P-loop), which may be fortuitous
YP_002342223.1	NMA0775,  integral membrane protein, len: 95 aa; unknown, shows weak similarity to NMA1798, fasta scores; E(): 4.5e-07, 34.8% identity in 92 aa overlap. Contains hydrophobic,  membrane-spanning regions
YP_002342224.1	NMA0776, probable cell-surface protein, len; 504 aa; highly similar to TR:O87783 (EMBL:AJ010115), tspB,Neisseria meningitidis strain B:15:P1.16 T-cell and B-cell antigen (partial CDS) (504 aa), fasta scores; E(): 0,54.8% identity in 485 aa overlap. Similar to others from Neisseria meningitidis, NMA1797, fasta scores; E(): 0,58.4% identity in 474 aa overlap, NMA1173, fasta scores; E(): 2.9e-21, 51.0% identity in 145 aa overlap and NMA2005, fasta scores; E(): 8.6e-19, 61.5% identity in 96 aa overlap. Contains a probable N-terminal signal sequence
YP_002342225.1	NMA0777, len: 101 aa; unknown, similar to others from Neisseria meningitidis, NMA1172, fasta scores; E(): 5.1e-16, 57.5% identity in 73 aa overlap and NMA2004,fasta scores; E(): 1.8e-14, 47.6% identity in 105 aa overlap
YP_002342226.1	NMA0778, unknown, len: 91 aa; shows weak similarity to TR:O82955 (EMBL:AB015669) ORF C4 from Burkholderia solanacearum plasmid pJTPS1 (111 aa), fasta scores; E(): 0.0061, 26.0% identity in 104 aa overlap. Similar to others from Neisseria meningitidis, NMA1171, fasta scores; E(): 3.1e-25, 58.7% identity in 92 aa overlap, NMA2003,fasta scores; E(): 3.1e-25, 58.7% identity in 92 aa overlap and NMA1796, fasta scores; E(): 5.9e-10, 30.4% identity in 92 aa overlap
YP_002342227.1	NMA0779,  integral membrane protein, len: 72 aa; similar to TR:O88142 (EMBL:AB012574), vpf77,hypothetical protein from Vibrio parahaemolyticus filamentous bacteriophage Vf12 (77 aa), fasta scores; E(): 0.64, 32.0% identity in 75 aa overlap. Similar to others from Neisseria meningitidis, NMA2002, fasta scores; E(): 2.8e-18, 72.2% identity in 72 aa overlap and NMA1170,fasta scores; E(): 2.8e-18, 72.2% identity in 72 aa overlap. Contains hydrophobic,  membrane-spanning regions
YP_002342228.1	NMA0780, len: 67 aa; unknown, similar to others from Neisseria meningitidis, NMA1794, fasta scores; E(): 2.6e-20, 58.5% identity in 65 aa overlap and NMA1169,fasta scores; E(): 3e-07, 36.1% identity in 61 aa overlap and NMA2001, fasta scores; E(): 3e-07, 36.1% identity in 61 aa overlap
YP_002342229.1	NMA0781, len: 103 aa; unknown, similar to others from Neisseria meningitidis, NMA1793, fasta scores; E(): 2.6e-30, 70.1% identity in 97 aa overlap, NMA1168, fasta scores; E(): 4.9e-11, 34.9% identity in 83 aa overlap and NMA2000, fasta scores; E(): 4.9e-11, 34.9% identity in 83 aa overlap
YP_002342230.1	NMA0782,  phage replication protein, len: 449 aa; shows weak similarity to e.g. TR:O34630 (EMBL:U83796) rstA2, Vibrio cholerae bacteriophage CTXphi protein required for replication and integration (359 aa),fasta scores; E(): 4.5e-10, 27.0% identity in 296 aa overlap. Also similar to TR:O82959 (EMBL:AB015669) ORF C7 from Burkholderia solanacearum plasmid pJTPS1 (444 aa),fasta scores; E (): 3.4e-15, 31.6% identity in 326 aa overlap. Similar to others from Neisseria meningitidis,NMA1792, E(): 0, 50.4% identity in 407 aa overlap,NMA1999, fasta scores; E(): 0, 42.7% identity in 337 aa overlap, and NMA1167, fasta scores; E(): 0, 42.7% identity in 337 aa overlap
YP_002342231.1	NMA0783, len: 71 aa; unknown
YP_002342232.1	NMA0784,  membrane protein, len: 173 aa; unknown, similar to others from Neisseria meningitidis,NMA1989, fasta scores; E(): 0, 82.7% identity in 173 aa overlap and NMA0786, fasta scores; E(): 0, 50.0% identity in 168 aa overlap. Within a region of unusually low GC content. Contains hydrophobic,  membrane-spanning regions
YP_002342233.1	NMA0785, len: 149 aa; unknown, similar to the N-terminal half of NMA0787, fasta scores; E(): 4.3e-33,73.5% identity in 132 aa overlap. Within a region of unusually low GC content
YP_002342234.1	NMA0786,  membrane protein, len: 168 aa; unknown, similar to NMA0784, fasta scores; E(): 0, 50.0% identity in 168 aa overlap and NMA1989, fasta scores; E(): 0, 47.6% identity in 168 aa overlap. Within a region of unusually low GC content. Contains hydrophobic,  membrane-spanning regions
YP_002342235.1	NMA0789, probable periplasmic binding protein, len: 308 aa; similar to binding protein components of ABC-transporters and to other binding proteins such as adhesins e.g. SW:ZNUA_ECOLI (EMBL:U38702), znuA,Escherichia coli high-affinity zinc uptake system component (328 aa), fasta scores; E(): 1.4e-13, 27.1% identity in 292 aa overlap and SW:ADHS_STRPA (EMBL:M26130), fimA, Streptococcus parasanguis adhesin B precursor (309 aa), fasta scores; E(): 1.2e-13, 26.0% identity in 304 aa overlap. Contains HD repeats from aa 115-134. Contains Pfam match to entry PF01297 Lipoprotein_4, Adhesion lipoprotein and probable N-terminal signal sequence
YP_002342236.1	NMA0790, probable ABC-transporter membrane protein,len: 291 aa; similar to many e.g. SW:MNTB_SYNY3 (EMBL:L34630), mntB, Synechocystis sp. (strain PCC 6803) manganese transport system membrane protein (306 aa),fasta scores; E(): 2.7e-21, 27.9% identity in 280 aa overlap. Contains Pfam match to entry PF00950 ABC-3, ABC 3 transport family and contains hydrophobic, membrane-spanning regions
YP_002342237.1	NMA0791, probable ABC-transporter ATP-binding protein, len: 251 aa; similar to many e.g. SW:MNTA_SYNY3 (EMBL:L34630), mntA, Synechocystis sp. (strain PCC 6803) manganese transport system ATP-binding protein (260 aa),fasta scores; E(): 2.7e-27, 38.8% identity in 232 aa overlap. Contains Pfam match to entry PF00005 ABC_tran,ABC transporter and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342238.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_002342239.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_002342240.1	Essential for efficient processing of 16S rRNA
YP_002342241.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_002342242.1	NMA0796, unknown, len: 808 aa; shows weak similarity in the N-terminal half to acyl-CoA synthetases e.g. TR:Q9ZER2 (EMBL:AJ012480) Pseudomonas mendocina pimeloyl-CoA synthetase (711 aa), fasta scores; E(): 3.3e-07, 22.0% identity in 496 aa overlap. Also similar to in part to many hypothetical proteins. The C-terminus contains a Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family
YP_002342243.1	NMA0797, probable two-component system sensor kinase, len: 468 aa; similar to many e.g. SW:BAES_ECOLI (EMBL:D14054), baeS, Escherichia coli sensor protein (EC 2.7.3.-) (467 aa), fasta scores; E(): 1.1e-21, 28.0% identity in 300 aa overlap. Contains Pfam matches to entry PF00512 signal, Signal carboxyl-terminal domain and to entry PF00672 DUF5, Domain found in bacterial signal proteins. Contains hydrophobic, probable membrane-spanning regions
YP_002342244.1	NMA0798, probable two-component system regulator,len: 225 aa; similar to many e.g. SW:OMPR_ECOLI (EMBL:J01656), ompR, Escherichia coli transcriptional regulatory protein (239 aa), fasta scores; E(): 1.7e-28,41.8% identity in 232 aa overlap. Contains Pfam matches to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal and to entry PF00072 response_reg,Response regulator receiver domain
YP_002342245.1	NMA0800,  integral membrane protein, len: 604 aa; unknown, shows very weak similarity to the N-terminal half of TR:AAD35888 (EMBL:AE001748) Thermotoga maritima hypothetical protein (1065 aa), fasta scores; E(): 0.014, 21.7% identity in 465 aa overlap. Contains hydrophobic, membrane-spanning regions
YP_002342246.1	NMA0801, len: 117 aa; unknown
YP_002342247.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002342248.1	NMA0803, tatC, probable sec-independent protein translocase component, len: 256 aa; similar to many e.g. SW:TATC_ECOLI (EMBL:AJ005830), tatC, mttB, Escherichia coli sec-independent protein translocase (258 aa),fasta scores; E(): 0, 50.2% identity in 247 aa overlap. Contains Pfam match to entry PF00902 UPF0032, MttB family. Contains hydrophobic,  membrane-spanning regions
YP_002342249.1	NMA0804,  sec-independent protein translocase component, len: 228 aa; the hydrophobic N-terminus is similar to the N-terminus of TR:O69415 (EMBL:AJ005830), tatB, Escherichia coli sec-independent protein translocase component (171 aa), fasta scores; E(): 0.0011, 38.6% identity in 70 aa overlap. This region is also similar to N-termini from several hypothetical proteins
YP_002342250.1	NMA0806,  nucleotide-binding protein, len: 107 aa; similar to members of the HIT (histidine triad) family e.g. SW:IPK1_RABIT (EMBL:Y11175), hinT, Oryctolagus cuniculus HinT protein (125 aa), fasta scores; E(): 5e-15,40.2% identity in 102 aa overlap. Highly similar to SW:HITA_NEIGO (EMBL:AF003550), hitA, Neisseria gonorrhoeae HitA protein (107 aa), fasta scores; E(): 0, 96.3% identity in 107 aa overlap. Contains Pfam match to entry PF01230 HIT, HIT family and PS00892 HIT family signature
YP_002342251.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
YP_002342252.1	NMA0808, probable zinc-binding alcohol dehydrogenase, len: 354 aa; similar to many e.g. TR:Q59696 (EMBL:L35343), adh, Pseudomonas putida 2,3-butanediol dehydrogenase (EC 1.1.1.4) (362 aa), fasta scores; E(): 0,38.2% identity in 356 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and PS00059 Zinc-containing alcohol dehydrogenases signature
YP_002342253.1	NMA0810, len: 385 aa; unknown, similar to members of the histone deacetylase/acetoin utilization/acetylpolyamine aminohydrolase family e.g. SW:Y245_SYNY3 (EMBL:D90900) Synechocystis sp. (strain PCC 6803) hypothetical protein (304 aa), fasta scores; E(): 8.2e-33, 35.7% identity in 300 aa overlap. Contains Pfam match to entry PF00850 Hist_deacetyl, Histone deacetylase family
YP_002342254.1	NMA0811, len: 88 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YAJC_ECOLI (EMBL:EG11096),yajC, Escherichia coli hypothetical protein (110 aa),fasta scores; E(): 6.9e-07, 35.2% identity in 88 aa overlap
YP_002342255.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_002342256.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_002342257.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_002342258.1	NMA0816, probable polyamine permease ATP-binding protein, len: 374 aa; similar to ATP-binding components of many polyamine permeases e.g. SW:POTG_ECOLI (EMBL:M93239),potG, Escherichia coli putrescine transport ATP-binding protein (404 aa), fasta scores; E(): 0, 54.2% identity in 395 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342259.1	NMA0817, probable polyamine permease inner membrane protein, len: 321 aa; similar to inner membrane components from many polyamine permeases e.g. SW:POTH_ECOLI (EMBL:M93239), potH, Escherichia coli putrescine transport system permease (317 aa), fasta scores; E(): 0,49.2% identity in 311 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains hydrophobic, probable membrane-spanning regions
YP_002342260.1	NMA0818, probable polyamine permease inner membrane protein, len: 295 aa; similar to inner membrane components from many polyamine permeases e.g. SW:POTI_ECOLI (EMBL:M93239), potI, Escherichia coli putrescine transport system permease (281 aa), fasta scores; E(): 0,54.7% identity in 278 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains hydrophobic, probable membrane-spanning regions
YP_002342261.1	NMA0819,  oxidoreductase, len: 431 aa; shows very weak similarity to several known oxidoreductases e.g. SW:SAOX_CORS1 (EMBL:U23955), soxB,Corynebacterium sp. sarcosine oxidase beta subunit (EC 1.5.3.1) (405 aa), fasta scores; E(): 6.8e-05, 23.7% identity in 414 aa overlap. Also similar to SW:ORDL_ECOLI (EMBL:U38543), ordL, Escherichia coli probable oxidoreductase (426 aa), fasta scores; E(): 0, 46.2% identity in 433 aa overlap
YP_002342262.1	NMA0820, amtB, probable ammonium transporter, len: 434 aa; similar to many of bacterial and eukaryotic origin e.g. TR:O67997 (EMBL:AF005275), amtB, Azospirillum brasilense (Methyl)ammonium transporter (438 aa), fasta scores; E(): 0, 54.7% identity in 428 aa overlap. Contains Pfam match to entry PF00909 Ammonium_transp, Ammonium Transporter Family and PS01219 Ammonium transporters signature. Contains hydrophobic,  membrane-spanning regions
YP_002342263.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_002342264.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002342265.1	NMA0827, len: 273 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YDIA_ECOLI (EMBL:AE000265) Escherichia coli hypothetical protein (277 aa), fasta scores; E(): 0, 47.4% identity in 270 aa overlap and to the C-terminal half of TR:O49562 (EMBL:AL021960) Arabidopsis thaliana hypothetical protein (403 aa), fasta scores; E(): 3.1e-16, 27.8% identity in 288 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342266.1	NMA0828, probable phosphatase, len: 220 aa; similar to many e.g. SW:GPHP_ALCEU (EMBL:M68905), cbbzP,Alcaligenes eutrophus phosphoglycolate phosphatase (231 aa), fasta scores; E(): 1.4e-13, 32.3% identity in 192 aa overlap and to  phosphatases found within polyketide biosynthesis operons e.g. TR:AAD31837 (EMBL:AF131879), ansH, Streptomyces collinus  phosphatase (268 aa), fasta scores; E(): 1.1e-11, 30.1% identity in 216 aa overlap. Also similar to NMA1688, fasta scores; E(): 2e-11, 27.8% identity in 227 aa overlap. Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase
YP_002342267.1	NMA0829, len: 275 aa; unknown, similar to SW:Y077_HAEIN (EMBL:U32693) Haemophilus influenzae hypothetical protein (288 aa), fasta scores; E(): 0, 48.9% identity in 272 aa overlap
YP_002342268.1	NMA0830,  periplasmic carrier protein, len: 207 aa; similar to e.g. SW:LOLA_ECOLI (EMBL:D49398), lolA,Escherichia coli outer membrane lipoproteins carrier protein precursor (204 aa), fasta scores; E(): 2.2e-11,29.4% identity in 197 aa overlap. Contains a N-terminal signal sequence
YP_002342269.1	NMA0831,  polyamine permease substrate-binding protein, len: 379 aa; similar to SW:POTF_ECOLI (EMBL:M93239), potF, Escherichia coli putrescine-binding periplasmic protein precursor (370 aa),fasta scores; E(): 0, 40.8% identity in 346 aa overlap. Also similar to NMA1786, fasta scores; E(): 0, 60.8% identity in 380 aa overlap and NMA2023, fasta scores; E(): 0, 54.8% identity in 396 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop) and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains a probable N-terminal signal sequence
YP_002342270.1	NMA0832,  glycosyl transferase, len: 383 aa; shows very weak similarity to several glycosyltransferases (some ) associated with capsule polysaccharide formation in pathogenic bacteria e.g. TR:AAD24457 (EMBL:AF118389), cps2K, Streptococcus suis  glycosyl transferase (276 aa), fasta scores; E(): 1.6e-07, 25.7% identity in 335 aa overlap. Contains 9x NNKQQTT repeats and has an unusually low GC content (31%). Contains Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferases
YP_002342271.1	NMA0833, len: 176 aa; unknown, similar to many hypothetical proteins e.g. part of SW:YRDA_ECOLI (EMBL:U18997) Escherichia coli hypothetical protein (256 aa), fasta scores; E(): 0, 62.4% identity in 173 aa overlap and to part of SW:CAIE_ECOLI (EMBL:X73904), caiE,Escherichia coli carnitine operon protein (203 aa), fasta scores; E(): 6.3e-16, 34.1% identity in 164 aa overlap. Contains a weak Pfam matches to entry PF00132 hexapep,Bacterial transferase hexapeptide (four repeats)
YP_002342272.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
YP_002342273.1	PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers
YP_002342274.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_002342275.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_002342276.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_002342277.1	NMA0841, probable phosphate acyltransferase, len: 500 aa; similar to many phosphate acetyltransferases,except over the N-terminal approx. 200 aa e.g. SW:PTA_ECOLI (EMBL:D17576), pta, Escherichia coli phosphate acetyltransferase (EC 2.3.1.8) (713 aa), fasta scores; E(): 0, 67.6% identity in 346 aa overlap. Contains Pfam match to entry PF01515 PTA_PTB, Phosphate acetyl/butaryl transferase
YP_002342278.1	NMA0842, fbpC, probable iron-uptake permease ATP-binding protein, len: 352 aa; similar to many ABC-transporter ATP-binding proteins involved in iron uptake e.g. TR:Q50966 (EMBL:U33937), fpbC, Neisseria gonorrhoeae iron-regulated protein (352 aa), fasta scores; E(): 0, 93.5% identity in 352 aa overlap and SW:SFUC_SERMA (EMBL:M33815), sfuC, Serratia marcescens iron(III)-transport ATP-binding protein (345 aa), fasta scores; E(): 0, 41.8% identity in 352 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter,PS00211 ABC transporters family signature and two PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342279.1	NMA0843, fbpB, probable iron-uptake permease inner membrane protein, len: 509 aa; similar to many binding protein dependent permease components e.g. TR:Q50965 (EMBL:U33937), fbpB, Neisseria gonorrhoeae iron-regulated protein (511 aa), fasta scores; E(): 0, 89.8% identity in 512 aa overlap and SW:SFUB_SERMA (EMBL:M33815), sfuB,Serratia marcescens iron(III)-transport system permease (527 aa), fasta scores; E(): 0, 36.6% identity in 497 aa overlap. Contains two Pfam matches to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains hydrophobic, probable membrane-spanning regions
YP_002342280.1	NMA0844, fbpA, major ferric iron binding protein,len: 331 aa; highly similar to many e.g. SW:FBP_NEIME (EMBL:X53467), fbpA, Neisseria meningitidis major ferric iron binding protein (330 aa), fasta scores; E(): 0, 98.8% identity in 331 aa overlap and probably constitutes the periplasmic binding component of an iron permease. Contains a probable N-terminal signal sequence
YP_002342281.1	NMA0846; unknown, fused with NMA0845 in MC58 and FAM18
YP_002342282.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_002342283.1	NMA0848, galU, probable UTP--glucose-1-phosphate uridylyltransferase, len: 289 aa; similar to many e.g. SW:GALU_ECOLI (EMBL:X59940), galU, Escherichia coli UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (301 aa), fasta scores; E(): 0, 50.2% identity in 291 aa overlap. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase
YP_002342284.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_002342285.1	NMA0850, len: 77 aa; unknown
YP_002342286.1	NMA0851, ppa, probable inorganic pyrophosphatase,len: 177 aa; similar to many e.g. SW:IPYR_SULAC (EMBL:X81842), ppa, Sulfolobus acidocaldarius inorganic pyrophosphatase (EC 3.6.1.1) (173 aa), fasta scores; E(): 4.5e-20, 41.0% identity in 166 aa overlap. Contains Pfam match to entry PF00719 Pyrophosphatase, Inorganic pyrophosphatase and PS00387 Inorganic pyrophosphatase signature
YP_002342287.1	converts dATP to dAMP and pyrophosphate
YP_002342288.1	NMA0853, mafB3, probable adhesin, len: 556 aa; similar, except at the C-terminus, to TR:AAD31039 (EMBL:AF142582), mafB, Neisseria gonorrhoeae adhesin (509 aa), E(): 9.1e-28, 32.0% identity in 425 aa overlap. Also similar to NMA2113, fasta scores; E(): 0, 38.6% identity in 412 aa overlap and NMA0324, fasta scores; (): 1.2e-27,33.5% identity in 376 aa overlap, differing from both at the C-terminus. Contains a probable N-terminal signal sequence
YP_002342289.1	NMA0854, len: 80 aa; unknown, within a region of unusually low GC content
YP_002342290.1	NMA0855, len: 81 aa; unknown, within a region of unusually low GC content
YP_002342291.1	NMA0856, len: 129 aa; unknown, similar to NMA0857,fasta scores; E(): 2.7e-34, 62.8% identity in 129 aa overlap and NMA0858, fasta scores; E(): 0, 67.4% identity in 129 aa overlap. Within a region of unusually low GC content
YP_002342292.1	NMA0857, len: 149 aa; unknown, similar to NMA0856,fasta scores; E(): 8e-34, 62.8% identity in 129 aa overlap and NMA0858, fasta scores; E(): 9.9e-32, 61.2% identity in 129 aa overlap. Within a region of unusually low GC content
YP_002342293.1	NMA0858, len: 129 aa; unknown, similar to NMA0856,fasta scores; E(): 0, 67.4% identity in 129 aa overlap and NMA0857, fasta scores; E(): 1.7e-31, 61.2% identity in 129 aa overlap. Within a region of unusually low GC content
YP_002342294.1	NMA0859, probable transmembrane potassium transporter, len: 485 aa; similar to many e.g. SW:TRKH_ECOLI (EMBL:M87049), trkH, Escherichia coli TRK system potassium uptake protein (483 aa), fasta scores; E(): 0, 41.8% identity in 486 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342295.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
YP_002342296.1	NMA0861, len: 129 aa; unknown, similar to many hypothetical proteins e.g. SW:YVN1_AZOVI (EMBL:M26752) Azotobacter vinelandii hypothetical protein (127 aa),fasta scores; E(): 2e-29, 66.9% identity in 127 aa overlap. Contains Pfam match to entry PF01042 DUF10,Domain of unknown function and PS01094 Hypothetical YER057c/yjjV family signature
YP_002342297.1	NMA0862, nspA, outer membrane protein, len: 174 aa; highly similar to surface antigens from other Neisseria meningitidis isolates e.g. TR:P96943 (EMBL:U52066) Neisseria meningitidis strain 608B outer membrane protein precursor (174 aa), fasta scores; E(): 0, 98.3% identity in 174 aa overlap. Contains an N-terminal signal sequence. Similar to NMA1890, NMA2043 and NMA1676, which contain short indels with respect to nspA
YP_002342298.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002342299.1	NMA0865, ligA, probable DNA ligase, len: 841 aa; similar to many e.g. SW:DNLJ_RHOMR (EMBL:U10483), ligA,Rhodothermus marinus DNA ligase (EC 6.5.1.2) (712 aa),fasta scores; E(): 0, 40.2% identity in 826 aa overlap. Contains Pfam matches to entry PF01653 DNA_ligase_N,NAD-dependent DNA ligase and to entry PF00533 BRCT, BRCA1 C Terminus (BRCT) domain. Contains PS01056 NAD-dependent DNA ligase signature 2 and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342300.1	NMA0866, len: 428 aa; unknown, N-terminus is hydrophobic, contains a PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342301.1	NMA0867, ampD, probable anhydro-N-acetylmuramyl-tripeptide amidase, len: 190 aa; similar to many e.g. TR:Q46960 (EMBL:U40806), ampD,Enterobacter cloacae anhydro-N-acetylmuramyl-tripeptide amidase (187 aa), fasta scores; E(): 0, 52.9% identity in 172 aa overlap
YP_002342302.1	NMA0868,  periplasmic protein, len: 331 aa; unknown, similar to many hypothetical proteins e.g. SW:YCEG_HAEIN (EMBL:U32728) Haemophilus influenzae hypothetical protein (347 aa), fasta scores; E(): 0, 44.2% identity in 260 aa overlap. Contains  N-terminal signal sequence
YP_002342303.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_002342304.1	NMA0870, maeA, probable malate oxidoreductase, len: 426 aa; similar to many e.g. SW:MAOX_BACST (EMBL:M19485) Bacillus stearothermophilus malate oxidoreductase (EC 1.1.1.38) (478 aa), fasta scores; E(): 0, 46.8% identity in 410 aa overlap. Contains PS00331 Malic enzymes signature
YP_002342305.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
YP_002342306.1	NMA0873,  periplasmic protein, len: 195 aa; unknown, contains probable N-terminal signal sequence
YP_002342307.1	NMA0874, len: 60 aa; unknown, similar to bacterial hypothetical proteins e.g. TR:BAA35663 (EMBL:D90730) Escherichia coli hypothetical protein (60 aa), fasta scores; E(): 1.3e-10, 48.3% identity in 60 aa overlap
YP_002342308.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_002342309.1	NMA0876, len: 133 aa; unknown, C-terminus contains a Neisseria meningitidis repeat, suggesting that the original C-terminus may have been removed by a recombination event
YP_002342310.1	NMA0877, len: 54 aa; unknown
YP_002342311.1	NMA0878, len: 38 aa; unknown
YP_002342312.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_002342313.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
YP_002342314.1	NMA0881, cnp1,  periplasmic protein, len: 203 aa; highly similar to TR:Q50984 (EMBL:M84111), cnp1,Neisseria gonorrhoeae cryptic protein precursor (203 aa),fasta scores; E(): 0, 92.1% identity in 203 aa overlap. Reported to be found in pathogenic Neisseria gonorrhoeae and Neisseria meningitidis species, but not in commensal species. Contains probable N-terminal signal sequence
YP_002342315.1	NMA0882, len: 74 aa; unknown, similar to hypothetical proteins e.g. SW:YRKI_BACSU (EMBL:D84432) Bacillus subtilis hypothetical protein (75 aa), fasta scores; E(): 6.6e-09, 38.0% identity in 71 aa overlap. Contains Pfam match to entry PF01206 UPF0033,Uncharacterized protein family UPF0033 and PS01148 Uncharacterized protein family UPF0033 signature
YP_002342316.1	NMA0883,  lipoprotein, len: 197 aa; unknown, contains probable N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342317.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_002342318.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_002342319.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_002342320.1	NMA0887, len: 107 aa; unknown
YP_002342321.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_002342322.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_002342323.1	catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis
YP_002342324.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002342325.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_002342326.1	NMA0894,  membrane protein, len: 165 aa; similar to SW:CVPA_ECOL (EMBL:J01666), cvpA, Escherichia coli colicin V production protein (162 aa), fasta scores; E(): 4.7e-10, 31.2% identity in 138 aa overlap. Contains hydrophobic, membrane-spanning regions
YP_002342327.1	NMA0895, tpc, tetrapac protein homologue, len: 332 aa; highly similar to TR:Q50991 (EMBL:Z68205), tpc,Neisseria gonorrhoeae tetrapac forming protein involved in natural transformation competence, epithelial cell invasion and cell separation (346 aa), fasta scores; E(): 0, 89.9% identity in 346 aa overlap. Contains an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342328.1	NMA0896, folC, bifunctional folylpolyglutamate synthase/dihydrofolate synthase, len: 424 aa; highly similar to many e.g. TR:Q50990 (EMBL:Z68205), folC,Neisseria gonorrhoeae bifunctional folylpolyglutamate synthase/dihydrofolate synthase (EC 6.3.2.17) (EC 6.3.2.12) (424 aa), fasta scores; E(): 0, 93.4% identity in 424 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family
YP_002342329.1	NMA0897, folI,  transcriptional regulator,len: 146 aa; highly similar to TR:Q50989 (EMBL:Z68205),folI, Neisseria gonorrhoeae  transcriptional activator (146 aa), fasta scores; E(): 0, 95.8% identity in 144 aa overlap. Note that activation of folC expression by folI provided in trans has only been demonstrated in Escherichia coli
YP_002342330.1	NMA0899, len: 124 aa; unknown
YP_002342331.1	NMA0900,  amino acid permease ATP-binding protein, len: 242 aa; similar to many e.g. SW:GLNQ_BACST (EMBL:M61017), glnQ, Bacillus stearothermophilus glutamine transport ATP-binding protein (242 aa), fasta scores; E(): 0, 63.2% identity in 242 aa overlap and SW:AAPP_RHILV (EMBL:X82596), aapP, Rhizobium leguminosarum general L-amino acid transport ATP-binding protein (257 aa), fasta scores; E(): 0, 56.9% identity in 239 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter,PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342332.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_002342333.1	NMA0903, len: 231 aa; unknown
YP_002342334.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_002342335.1	NMA0905, iga, IgA1 protease, len: 1773 aa; highly similar to IgA1 proteases from Neisseria and Haemophilus species e.g. TR:Q51169 (EMBL:X82474), iga, Neisseria meningitidis HF13 IgA1 protease (1561 aa), fasta scores; E(): 0, 77.9% identity in 1784 aa overlap. Also similar to NMA0457, iga2 (29.9% identity in 1339 aa overlap)
YP_002342336.1	NMA0906, comA, competence protein, len: 691 aa; highly similar to SW:COMA_NEIGO (EMBL:S75490), comA,Neisseria gonorrhoeae competence protein essential for natural transformation (691 aa), fasta scores; E(): 0,95.1% identity in 691 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily. Contains hydrophobic, probable membrane-spanning regions
YP_002342337.1	NMA0907, comL, competence lipoprotein, len: 267 aa; highly similar to SW:COML_NEIGO (EMBL:Z49895), comL,Neisseria gonorrhoeae competence lipoprotein (267 aa),fasta scores; E(): 0, 98.5% identity in 267 aa overlap. Contains an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site and a probable N-terminal signal sequence
YP_002342338.1	NMA0908, rluD, probable ribosomal large subunit pseudouridine synthase D, len: 374 aa; similar to many e.g. SW:RLUD_ECOLI (EMBL:U50134), rluD, Escherichia coli ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) (326 aa), fasta scores; E(): 0, 49.5% identity in 323 aa overlap. This protein has an N-terminal extension of approx. 20 aa which is not present in otherwise similar proteins. Contains Pfam matches to entry PF01479 S4, S4 domain and to entry PF00849 YABO,Hypothetical yabO/yceC/sfhB family. Contains PS01129 Hypothetical yabO/yceC/sfhB family signature
YP_002342339.1	NMA0909, probable transmembrane transport protein,len: 315 aa; similar to many eukaryotic (Na)+ dependent transporters e.g. SW:NTCI_HUMAN (EMBL:U10417), SLC10A2,Homo sapiens ileal sodium/bile acid cotransporter (348 aa), fasta scores; E(): 9.9e-19, 31.4% identity in 287 aa overlap. Also similar to bacterial hypothetical proteins e.g. TR:O34524 (EMBL:AF027868), yocS, Bacillus subtilis  transporter (321 aa), fasta scores; E(): 0, 58.1% identity in 313 aa overlap. Similar to NMA0046, fasta scores; E(): 0, 37.4% identity in 310 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342340.1	NMA0911, len: 259 aa; unknown, similar to many bacterial hypothetical proteins e.g. SW:YFIH_ECOLI (EMBL:U50134), yfiH, Escherichia coli hypothetical protein (243 aa), fasta scores; E(): 0, 50.4% identity in 240 aa overlap
YP_002342341.1	NMA0912, probable lipoprotein, len; 159 aa; similar to SW:RLPB_ECOLI (EMBL:M18277), rlpB, Escherichia coli rare lipoprotein B precursor (193 aa), fasta scores; E(): 1.9e-07, 30.3% identity in 165 aa overlap. Contains an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site and a probable N-terminal signal sequence
YP_002342342.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_002342343.1	NMA0914,  membrane protein, len: 139 aa; unknown, contains hydrophobic,  membrane-spanning regions
YP_002342344.1	NMA0915, len: 170 aa; unknown, contains hydrophobic,  membrane-spanning regions
YP_002342345.1	NMA0916, len: 294 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YICC_ECOLI (EMBL:L10328),yicC, Escherichia coli hypothetical protein (287 aa),fasta scores; E(): 0, 41.0% identity in 290 aa overlap
YP_002342346.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_002342347.1	Transfers the fatty acyl group on membrane lipoproteins
YP_002342348.1	NMA0919, similar to hypothetical proteins from Escherichia coli and Mycobacterium tuberculosis e.g. SW:YEDI_ECOLI (EMBL:AE000287), yedI, Escherichia coli hypothetical protein (305 aa), fasta scores; E(): 7.7e-24,60.5% identity in 114 aa overlap
YP_002342349.1	NMA0921, similar to hypothetical proteins from Escherichia coli e.g. SW:YCGO_ECOLI (EMBL:AE000217), ycgO,Escherichia coli  Na(+)/H(+) exchanger (578 aa),blastp score; Expect = 2.3e-11
YP_002342351.1	NMA0925,  cytochrome C, len: 163 aa; shows very weak similarity to many e.g. SW:C552_THETH (EMBL:M93437), cycA, Thermus aquaticus cytochrome C-552 precursor (148 aa), fasta scores; E(): 0.00017, 33.6% identity in 137 aa overlap. Contains Pfam match to entry PF00034 cytochrome_c, Cytochrome c and PS00190 Cytochrome c family heme-binding site signature. Contains a probable N-terminal signal sequence
YP_002342352.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_002342353.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_002342354.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_002342355.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_002342356.1	NMA0931, rpmI, probable 50S ribosomal protein L35,len: 65 aa; similar to many e.g. SW:RL35_ECOLI (EMBL:AE000266), rpmI, Escherichia coli 50S ribosomal protein L35 (64 aa), fasta scores; E(): 2.4e-10, 57.8% identity in 64 aa overlap. Contains Pfam match to entry PF01632 Ribosomal_L35p, Ribosomal protein L35 and PS00936 Ribosomal protein L35 signature
YP_002342357.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_002342358.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_002342359.1	NMA0935, len: 354 aa; unknown, lies in a region of unusually low GC content. Similar to NMA0346, fasta scores; E(): 8.4e-19, 28.9% identity in 339 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342360.1	NMA0936, len: 172 aa; unknown, lies in a region of unusually low GC content
YP_002342361.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_002342362.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_002342363.1	NMA0939, len: 96 aa; unknown
YP_002342364.1	F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein
YP_002342365.1	NMA0941, len: 79 aa; unknown
YP_002342366.1	NMA0942, bioA, probable adenosylmethionine-8-amino-7-oxononanoate aminotransferase, len: 433 aa; similar to many e.g. SW:BIOA_ECOLI (EMBL:J04423), bioA, Escherichia coli adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (429 aa), fasta scores; E(): 0, 58.4% identity in 418 aa overlap. Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate and PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site
YP_002342367.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_002342368.1	NMA0944, len: 158 aa, unknown, shows very weak similarity in the C-terminus to SW:UBIC_ECOLI (EMBL:M93136), ubiC, Escherichia coli chorismate--pyruvate lyase (EC 4.-.-.-) (164 aa), fasta scores; E(): 0.0086,34.1% identity in 91 aa overlap
YP_002342369.1	catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway
YP_002342370.1	NMA0946,  regulatory protein, len: 149 aa; similar to CDS from several rpoN operons e.g. SW:PTSN_ECOLI (EMBL:U12684), ptsN, Escherichia coli nitrogen regulatory IIA protein (EC 2.7.1.69) (163 aa),fasta scores; E(): 9.4e-17, 42.6% identity in 129 aa overlap, which influences transcription of sigma 54-dependent genes. Contains Pfam match to entry PF00359 PTS_EIIA_2, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 and PS00372 PTS EIIA domains phosphorylation site signature 2
YP_002342371.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
YP_002342372.1	NMA0948, len: 284 aa; similar to many e.g. TR:Q9ZA87 (EMBL:AF088980) Proteus mirabilis protein (284 aa), fasta scores; E(): 0, 44.0% identity in 282 aa overlap. Proteus mirabilis mutated in this gene exhibit reduced virulence in a mouse model of ascending urinary tract infection. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342373.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
YP_002342374.1	NMA0951, len: 200 aa; unknown, similar to bacterial hypothetical proteins e.g. TR:O83471 (EMBL:AE001223),TP0458, Treponema pallidum hypothetical protein (192 aa),fasta scores; E(): 4.9e-12, 38.2% identity in 173 aa overlap
YP_002342375.1	NMA0952, recN, probable DNA repair protein, len: 557 aa; similar to many e.g. SW:RECN_ECOLI (EMBL:Y00357),recN, Escherichia coli DNA repair protein (553 aa), fasta scores; E():0, 39.1% identity in 553 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342376.1	NMA0954, len: 539 aa; unknown, similar to parts of bacterial hypothetical proteins e.g. TR:P77182 (EMBL:AE000321) Escherichia coli hypothetical protein (688 aa), fasta scores; E(): 1.7e-28, 26.8% identity in 477 aa overlap
YP_002342377.1	NMA0955, len: 130 aa; unknown, similar to bacterial hypothetical proteins e.g. TR:Q51512 (EMBL:X66592) Pseudomonas aeruginosa hypothetical protein (123 aa),fasta scores; E(): 5.6e-22, 56.3% identity in 112 aa overlap
YP_002342378.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
YP_002342379.1	NMA0957, len: 159 aa; unknown
YP_002342380.1	NMA0958, folK, probable 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine- pyrophosphokinase, len: 164 aa; similar to many e.g. SW:HPPK_ECOLI (EMBL:L06495), folK, Escherichia coli 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (158 aa), fasta scores; E(): 1.2e-15, 43.0% identity in 135 aa overlap. Contains fam match to entry PF01288 HPPK,7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase (HPPK)
YP_002342381.1	NMA0959,  regulator, len: 124 aa; similar to TR:AAD32201 (EMBL:AF134855), sirB ORF1, Salmonella typhimurium protein affecting expression of a type III secretion system within Salmonella pathogenicity island 1 (129 aa), fasta scores; E(): 3.3e-06, 31.9% identity in 119 aa overlap and TR:Q46755 (EMBL:U18555) Escherichia coli hypothetical protein within kdsA operon (130 aa),fasta scores; E(): 1.3e-06, 29.3% identity in 116 aa overlap
YP_002342382.1	NMA0960, len: 188 aa; unknown, similar to bacterial hypothetical proteins e.g. TR:O34614 (EMBL:AF008220),ytqB, Bacillus subtilis hypothetical protein (194 aa),fasta scores; E(): 3.1e-28, 41.4% identity in 191 aa overlap
YP_002342383.1	NMA0961, hfq, probable regulator, len: 97 aa; similar to many e.g. TR:Q56928 (EMBL:D28762), ymr,Yersinia enterocolitica positive regulator of expression of heat-stable enterotoxin gene (101 aa), fasta scores; E(): 3.3e-20, 65.6% identity in 96 aa overlap, TR:AAD38187 (EMBL:AF154075), hfq, Brucella abortus host factor I protein which is a major determinant of virulence in mice (78 aa), fasta scores; E(): 2.4e-11, 51.4% identity in 72 aa overlap and SW:HFQ_ECOLI (EMBL:D00743), hfq,Escherichia coli host factor-I protein for bacteriophage Q beta (101 aa), fasta scores; E(): 1e-19, 63.0% identity in 100 aa overlap
YP_002342384.1	NMA0962, probable D-alanyl-D-alanine-endopeptidase,len: 312 aa; similar to many penicillin-binding proteins e.g. TR:AF156692 (EMBL:AF156692), pbp4, Neisseria gonorrhoeae penicillin-binding protein 4 (312 aa), fasta scores; E(): 0, 98.1% identity in 312 aa overlap and SW:PBP5_PSEAE (EMBL:U62582), pbpG, Pseudomonas aeruginosa penicillin-binding protein 5 precursor (EC 3.4.-.-) (311 aa), fasta scores; E(): 0, 43.8% identity in 240 aa overlap. Similar to part of NMA1095, fasta scores; E(): 1.2e-13, 29.6% identity in 243 aa overlap. Contains Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase
YP_002342385.1	NMA0963, len: 167 aa; unknown, similar to many bacterial proteins of unknown function e.g. TR:P72697 (EMBL:D90900), bcp, Synechocystis sp. bacterioferritin comigratory protein (160 aa), fasta scores; E(): 4.3e-22,45.1% identity in 142 aa overlap. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family
YP_002342386.1	NMA0964, xerD, probable integrase/recombinase, len: 291 aa; similar to many e.g. SW:XERD_ECOLI (EMBL:M54884),xerD, Escherichia coli integrase/recombinase (298 aa),fasta scores; E(): 0, 48.6% identity in 290 aa overlap. Contains Pfam match to entry PF00589 Phage_integrase,'Phage' integrase family. Similar to NMA0588, fasta scores; E(): 2.9e-30, 35.0% identity in 294 aa overlap
YP_002342387.1	NMA0965, probable ferredoxin, len: 66 aa; similar to many e.g. SW:BFD_ECOLI (EMBL:M27176), bfd, Escherichia coli bacterioferritin-associated ferredoxin (64 aa), fasta scores; E(): 0.47, 28.6% identity in 42 aa overlap
YP_002342388.1	NMA0966,  thioredoxin, len: 77 aa; shows weak similarity to many e.g. TR:CAB40815 (EMBL:AJ133006),trxA, Listeria monocytogenes thioredoxin (EC 1.8.1.9) (103 aa), fasta scores; E(): 0.41, 33.8% identity in 65 aa overlap and SW:YV35_MYCTU (EMBL:Z77162) Mycobacterium tuberculosis hypothetical protein (97 aa), fasta scores; E(): 4e-05, 29.8% identity in 84 aa overlap. Contains PS00190 Cytochrome c family heme-binding site signature
YP_002342389.1	NMA0967, rfbD, probable dTDP-4-dehydrorhamnose reductase, len: 287 aa; similar to many e.g. SW:RFBD_SALTY (EMBL:X56793), rfbD, Salmonella typhimurium dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) (299 aa),fasta scores; E(): 0, 39.0% identity in 295 aa overlap
YP_002342390.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_002342391.1	NMA0969, pnp, probable polyribonucleotide nucleotidyltransferase, len: 706 aa; similar to many e.g. SW:PNP_PHOLU (EMBL:X76069), pnp, Photorhabdus luminescens polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (709 aa), fasta scores; E(): 0, 63.7% identity in 703 aa overlap. Contains two Pfam matches to entry PF01138 RNase_PH, 3' exoribonuclease family, Pfam match to entry PF00013 KH-domain, KH domain and Pfam match to entry PF00575 S1, S1 RNA binding domain
YP_002342392.1	NMA0970, len: 222 aa; unknown
YP_002342393.1	NMA0971,  lipoprotein, len: 98 aa; unknown,contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342394.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_002342395.1	NMA0973, probable integral membrane protein, len: 201 aa; unknown. Contains hydrophobic, probable membrane-spanning regions
YP_002342396.1	NMA0974, cysK, probable cysteine synthase, len: 310 aa; similar to many from bacteria and eukaryotes e.g. SW:CYSK_SPIOL (EMBL:D10476), cysK, Spinacia oleracea cysteine synthase (EC 2.5.1.47) (325 aa), fasta scores; E(): 0, 58.1% identity in 310 aa overlap. Contains Pfam match to entry PF00291 S_T_dehydratase,Pyridoxal-phosphate dependent enzymes and PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site
YP_002342397.1	NMA0975, probable integral membrane protein, len: 292 aa; unknown, shows weak similarity to bacterial hypothetical proteins e.g. SW:YDED_ECOLI (EMBL:AE000250),ydeD, Escherichia coli hypothetical protein (266 aa),fasta scores; E(): 1.4e-07, 27.8% identity in 255 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342398.1	NMA0976, lepB, probable signal peptidase I, len: 292 aa; similar to many e.g. SW:LEP_ECOLI (EMBL:K00426),lepB, Escherichia coli signal peptidase I (EC 3.4.21.89) (324 aa), fasta scores; E(): 1.5e-27, 40.9% identity in 257 aa overlap. The N-terminus differs from its homologues. A  start codon chosen with reference to the N-terminal membrane-spanning regions found in characterised signal peptidases. Contains two Pfam match to entry PF00461 Peptidase_S26, Signal peptidase I,PS00760 Signal peptidases I lysine active site and PS00761 Signal peptidases I signature 3
YP_002342399.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_002342400.1	NMA0978, pfs, probable 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, len: 233 aa; similar to many e.g. SW:PFS_ECOLI (EMBL:U24438), pfs, Escherichia coli MTA/SAH nucleosidase (EC 3.2.2.16) (EC 3.2.2.9) (232 aa), fasta scores; E(): 0, 47.8% identity in 228 aa overlap. Contains Pfam match to entry PF01048 PNP_UDP_1, Phosphorylase family
YP_002342401.1	NMA0979, pilT2,  pilus retraction protein,len: 370 aa; similar to many e.g. SW:PILT_PSEAE (EMBL:M55524), pilT, Pseudomonas aeruginosa twitching mobility protein which complements mutants deficient in this function (344 aa), fasta scores; E(): 0, 43.8% identity in 329 aa overlap. Similar to TR:O85741 (EMBL:AF074716), pilT, from Neisseria meningitidis (strain 8013) (347 aa), fasta scores; E(): 0, 40.9% identity in 335 aa overlap. Shows weaker similarity to bacterial type II secretion proteins e.g. SW:GSPE_KLEPN (EMBL:M32613),pulE, Klebsiella pneumoniae general secretion pathway protein (497 aa), fasta scores; E(): 5.6e-14, 33.1% identity in 281 aa overlap. Also similar to NMA0218, fasta scores; E(): 0, 40.1% identity in 334 aa overlap and NMA0219, fasta scores; E(): 0, 44.8% identity in 348 aa overlap. Contains Pfam match to entry PF00437 GSPII_E,Bacterial type II secretion system protein, PS00662 Bacterial type II secretion system protein E signature and PS00017 ATP/GTP-binding site motif A (P-loop). Also similar to pilT NMA0218 (40.1% identity in 334 aa overlap), and pilU NMA0219 (44.8% identity in 348 aa overlap)
YP_002342402.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_002342403.1	NMA0981,  pilus biogenesis protein, len: 116 aa; similar to TR:Q51538 (EMBL:L42622), pilZ,Pseudomonas aeruginosa protein involved in biogenesis of type 4 fimbriae (118 aa), fasta scores; E(): 9.9e-12,31.5% identity in 108 aa overlap
YP_002342404.1	NMA0982, len: 259 aa; unknown, similar to many hypothetical proteins e.g. SW:YCFH_ECOLI (EMBL:AE000210),ycfH, Escherichia coli hypothetical protein (265 aa),fasta scores; E(): 0, 44.7% identity in 255 aa overlap. Contains Pfam match to entry PF01026 UPF0006,Uncharacterized protein family and PS01137 Uncharacterized protein family UPF0006 signature 1
YP_002342405.1	NMA0984, len: 103 aa; unknown, similar to many hypothetical proteins, some of which are glutaredoxin-like e.g. SW:YI46_SYNY3 (EMBL:D90903) Synechocystis sp. hypothetical protein (107 aa), fasta scores; E(): 7.4e-24,62.5% identity in 96 aa overlap. No N-terminal CXXC  active site residues are apparent in this CDS
YP_002342406.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_002342407.1	NMA0986, len: 106 aa; unknown
YP_002342408.1	NMA0987, probable secreted protein, len: 140 aa; unknown, highly similar to TR:O30392 (EMBL:AF003941),gly1ORF1, Neisseria gonorrhoeae PilA-regulated protein (140 aa), fasta scores; E(): 0, 97.9% identity in 140 aa overlap. Found in outer membrane preparations of wild-type N. gonorrhoeae. A knockout of the gly1 locus results in increased toxicity of the strain to human fallopian tube organ cultures. Contains an N-terminal signal sequence
YP_002342409.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis
YP_002342410.1	NMA0989, len: 424 aa; unknown, shows weak similarity to  uroporphyrin-III C-methyltransferase from Escherichia coli and Haemophilus influenzae, e.g. SW:HEMX_ECOLI (EMBL:X13406), hemX,Escherichia coli uroporphyrin-III C-methyltransferase (EC 2.1.1.107) (393 aa), fasta scores; E(): 8.1e-17, 25.4% identity in 389 aa overlap
YP_002342411.1	NMA0990, len: 405 aa; unknown
YP_002342412.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_002342413.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_002342414.1	NMA0993,  periplasmic protein, len: 159 aa; unknown, similar to TR:O83865 (EMBL:AE001259) Treponema pallidum hypothetical protein (168 aa), fasta scores; E(): 2.1e-16, 35.9% identity in 153 aa overlap. Contains a N-terminal signal sequence
YP_002342415.1	NMA0994,  periplasmic protein, len: 119 aa; unknown, shows weak similarity to SW:PSPE_ECOLI (EMBL:X57560), pspE, Escherichia coli phage shock protein (104 aa), fasta scores; E(): 1.9e-09, 40.9% identity in 88 aa overlap. Contains Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain. Contains a  N-terminal signal sequence
YP_002342416.1	NMA0995, recB, probable exodeoxyribonuclease V beta chain, len: 1204 aa; similar to bacterial deoxyribonucleases e.g. SW:EX5B_ECOLI (EMBL:X04581), recB,Escherichia coli exodeoxyribonuclease V beta chain (EC 3.1.11.5) (1180 aa),fasta scores; E(): 0, 32.2% identity in 1241 aa overlap. Contains Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase and two PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342417.1	NMA0996, len: 302 aa; unknown, similar to TR:P76536 (EMBL:AE000330) Escherichia coli hypothetical protein (308 aa), fasta scores; E(): 0, 49.7% identity in 302 aa overlap and TR:O07180 (EMBL:Z96797) Mycobacterium tuberculosis hypothetical protein (335 aa), fasta scores; E(): 5.3e-33, 34.5% identity in 304 aa overlap
YP_002342418.1	NMA0997, probable amino acid permease substrate-binding protein, len: 275 aa; similar to many e.g. SW:HISJ_ECOLI (EMBL:U47027), hisJ, Escherichia coli histidine-binding periplasmic protein precursor (260 aa),fasta scores; E(): 5.2e-13, 27.6% identity in 232 aa overlap. Similar to many hypothetical binding proteins e.g. TR:Q9ZKR0 (EMBL:AE001517) Helicobacter pylori J99 amino acid abc transporter, binding protein precursor (257 aa), fasta scores; E(): 0, 54.4% identity in 237 aa overlap. Contains Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3, PS01039 Bacterial extracellular solute-binding proteins, family 3 signature and PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains a probable N-terminal signal sequence
YP_002342419.1	NMA0999, probable amino acid permease integral membrane protein, len: 238 aa; similar to many e.g. SW:GLNP_ECOLI (EMBL:X14180), glnP, Escherichia coli glutamine transport system permease (219 aa),fasta scores; E(): 1.2e-20, 34.0% identity in 209 aa overlap. Similar to many hypothetical permease integral membrane proteins e.g. TR:Q9ZKR1 (EMBL:AE001517) Helicobacter pylori J99  amino acid abc transporter, permease (237 aa), fasta scores; E(): 0, 58.4% identity in 226 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains hydrophobic, probable membrane-spanning regions
YP_002342420.1	NMA1000, probable amino acid permease ATP-binding protein, len: 251 aa; similar to many e.g. SW:GLNQ_BACST (EMBL:M61017), glnQ, Bacillus stearothermophilus glutamine transport ATP-binding protein (242 aa), E(): 0, 52.6% identity in 247 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342421.1	NMA1001, pgm, phosphoglucomutase, len: 460 aa; highly similar to SW:PGMU_NEIME (EMBL:U02490), pgm,Neisseria meningitidis strain NMB phosphoglucomutase (EC 5.4.2.2) (460 aa), fasta scores; E(): 0, 94.3% identity in 460 aa overlap. Contains Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase and PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature
YP_002342422.1	NMA1002, ppiB, probable peptidyl-prolyl cis-trans isomerase B, len: 169 aa; similar to many e.g. SW:CYPB_ECOLI (EMBL:M55430), ppiB, Escherichia coli peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) (164 aa), fasta scores; E(): 0, 58.9% identity in 163 aa overlap. Also similar to NMA1469, fasta scores; E(): 2.3e-21, 46.3% identity in 162 aa overlap. Contains Pfam match to entry PF00160 pro_isomerase, Peptidyl-prolyl cis-trans isomerase and PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature
YP_002342423.1	NMA1003, probable transmembrane transport protein,len: 471 aa; similar to many e.g. to part of SW:PH87_YEAST (EMBL:X56909), PHO87, Saccharomyces cerevisiae inorganic phosphate transporter (923 aa), fasta scores; E(): 6.2e-20, 27.1% identity in 425 aa overlap and to hypothetical transporters e.g. SW:Y608_HAEIN (EMBL:U32743), HI0608, Haemophilus influenzae hypothetical protein (461 aa), fasta scores; E(): 0, 56.3% identity in 448 aa overlap. Contains Pfam match to entry PF00939 Na_sulph_symp, Sodium:sulfate symporter transmembrane region and PS01271 Sodium:sulfate symporter family signature. Contains hydrophobic, probable membrane-spanning regions
YP_002342425.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_002342426.1	NMA1005, len: 92 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YFJF_HAEIN (EMBL:U32723),HI0395, Haemophilus influenzae hypothetical protein (102 aa), fasta scores; E(): 2.6e-14, 48.3% identity in 89 aa overlap
YP_002342427.1	NMA1006, len: 147 aa; unknown, similar to bacterial hypothetical proteins e.g. TR:O68560 (EMBL:AF050676) Pseudomonas aeruginosa hypothetical protein (144 aa),fasta scores; E(): 1.8e-17, 34.5% identity in 139 aa overlap
YP_002342428.1	NMA1007, ftsH, probable ATP-dependent zinc metallopeptidase, len: 655 aa; similar to many e.g. SW:FTSH_ECOLI (EMBL:M83138), ftsH, Escherichia coli cell division protein (EC 3.4.24.-) (644 aa), fasta scores; E(): 0, 58.5% identity in 646 aa overlap. Contains Pfam matches to entry PF00004 AAA, ATPases associated with various cellular activities (AAA) and to entry PF01434 Peptidase_M41, Peptidase family M41, PS00674 AAA-protein family signature and two PS00017 ATP/GTP-binding site motif A (P-loop). Contains hydrophobic, probable membrane-spanning regions
YP_002342429.1	NMA1008, ftsJ, probable cell division protein, len: 106 aa; similar to many e.g. SW:FTSJ_ECOLI (EMBL:M83138),ftsJ, Escherichia coli cell division protein (209 aa),fasta scores; E(): 0, 49.0% identity in 204 aa overlap
YP_002342430.1	NMA1009, len: 94 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YHBY_HAEIN (EMBL:U32812),HI1333, Haemophilus influenzae hypothetical protein (99 aa), fasta scores; E(): 5.3e-12, 48.9% identity in 90 aa overlap
YP_002342431.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_002342432.1	NMA1012, probable carbon-sulphur lyase, len: 385 aa; similar to many members of the pyridoxal-phosphate dependent cysteine and methionine metabolism family e.g. SW:MEGL_PSEPU (EMBL:D88554), mdeA, Pseudomonas putida methionine gamma-lyase (EC 4.4.1.11) (398 aa), fasta scores; E(): 0, 39.3% identity in 402 aa overlap and SW:METB_ECOLI (EMBL:K01546), metB, Escherichia coli cystathionine gamma-synthase (EC 4.2.99.9) (386 aa), fasta scores; E(): 0, 39.4% identity in 376 aa overlap. Contains Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme and PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site
YP_002342433.1	similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis
YP_002342434.1	NMA1015, probable NAD(P)H-flavin oxidoreductase,len: 221 aa; similar to many e.g. SW:NFNB_SALTY (EMBL:X17250), nfnB, Salmonella typhimurium oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) (217 aa), fasta scores; E(): 8.7e-13, 31.4% identity in 223 aa overlap and SW:NFNB_ECOLI (EMBL:D25414), nfnB,Escherichia coli dihydropteridine reductase (EC 1.6.99.7) (217 aa), fasta scores; E(): 3.6e-11, 31.5% identity in 219 aa overlap. Contains Pfam match to entry PF00881 Nitroreductase, Nitroreductase family
YP_002342435.1	NMA1016, probable RNA-binding protein, len: 252 aa; shows weak similarity to pseudouridine synthases e.g. SW:RSUA_ECOLI (EMBL:U00008), rluA, Escherichia coli ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) (231 aa), fasta scores; E(): 1.4e-09, 30.2% identity in 242 aa overlap. Also shows weak similarity to NMA1573, fasta scores; E(): 4.2e-13, 35.5% identity in 248 aa overlap and NMA1508, fasta scores; E(): 2.7e-10, 26.1% identity in 241 aa overlap. Contains Pfam match to entry PF01479 S4, S4 domain
YP_002342436.1	catalyzes the phosphorylation of NAD to NADP
YP_002342437.1	NMA1018, len: 188 aa; unknown
YP_002342438.1	NMA1019, len: 258 aa; unknown, similar to SW:YEEZ_ECOLI (EMBL:AE000293), yeeZ, Escherichia coli hypothetical protein (274 aa), fasta scores; E(): 6e-17,30.9% identity in 256 aa overlap
YP_002342439.1	NMA1020, probable tetR-family transcriptional regulator, len: 216 aa; similar to many e.g. to the N-terminus of TR:Q9Z480 (EMBL:AF090987), tetR,Agrobacterium tumefaciens C58 transcriptional repressor (215 aa), fasta scores; E(): 0.00072, 40.0% identity in 75 aa overlap and to  regulators e.g. .Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family. Contains a probable helix-turn-helix motif at aa 32-53 (Score 1664, +4.85 SD)
YP_002342440.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_002342441.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
YP_002342442.1	May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
YP_002342443.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_002342444.1	NMA1025, len: 86 aa; unknown
YP_002342445.1	NMA1026, len: 127 aa; unknown, similar to others from Neisseria meningitidis e.g. NMA1028, fasta scores; E(): 1.3e-13, 35.4% identity in 130 aa overlap, also to NMA1027 and NMA0096
YP_002342446.1	NMA1027,  DNA-binding protein, len: 136 aa; similar to others from Neisseria meningitidis e.g. NMA1028, fasta scores; E(): 7e-21, 42.7% identity in 131 aa overlap, also to NMA0096 and NMA1026. Contains probable helix-turn-helix motif at aa 96-117 (Score 1404, +3.97 SD)
YP_002342447.1	NMA1028,  DNA-binding protein, len: 130 aa; similar to others from Neisseria meningitidis e.g. NMA1027, fasta scores; E(): 1.4e-20, 42.7% identity in 131 aa overlap, also to NMA0096 and NMA1026. Contains probable helix-turn-helix motif at aa 90-111 (Score 1103, +2.94 SD)
YP_002342448.1	NMA1030, len: 167 aa; unknown
YP_002342449.1	metalloprotease
YP_002342450.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_002342451.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_002342452.1	NMA1034, rfaE, probable ADP-heptose synthetase,len: 323 aa; similar to many e.g. SW:RFAE_ECOLI (EMBL:AE000387), rfaE, Escherichia coli ADP-heptose synthase (EC 2.7.-.-) (477 aa), fasta scores; E(): 0,50.5% identity in 309 aa overlap and to TR:AAD32179 (EMBL:AF125564), rfaE, Neisseria meningitidis  ADP-heptose synthetase (fragment) (313 aa), fasta scores; E(): 0, 96.8% identity in 313 aa overlap. Contains PS00583 pfkB family of carbohydrate kinases signature 1
YP_002342453.1	NMA1035, nmgII, probable modification methylase,len: 411 aa; similar to many e.g. SW:MTS2_SHISO (EMBL:M86545), ssoIIM, Shigella sonnei modification methylase (EC ) (379 aa), fasta scores; E(): 6e-30, 31.7% identity in 398 aa overlap and to TR:AAD32180 (EMBL:AF125564), nmgII, Neisseria meningitidis NMB  site specific dna methyltransferase (411 aa),E(): 0, 99.3% identity in 411 aa overlap. Similar to others from Neisseria meningitidis e.g. NMA1453, fasta scores; E(): 1.6e-23, 29.4% identity in 432 aa overlap. Contains two Pfam matches to entry PF00145 DNA_methylase,C-5 cytosine-specific DNA methylase, PS00095 C-5 cytosine-specific DNA methylases C-terminal signature and PS00094 C-5 cytosine-specific DNA methylases active site
YP_002342454.1	NMA1036, nmgI,  type II restriction endonuclease, len: 372 aa; shows weak similarity to the C-termini of restriction endonucleases e.g. TR:O30359 (EMBL:AF001598), dcrH, Neisseria gonorrhoeae restriction endonuclease (374 aa), fasta scores; E(): 1e-05, 33.0% identity in 109 aa overlap. Similar to TR:AAD32181 (EMBL:AF125564), nmgI, Neisseria meningitidis NMB  restriction endonuclease (374 aa), fasta scores; E(): 0,97.9% identity in 374 aa overlap. Lies within a region of unusually low GC content, adjacent to a  modification methylase
YP_002342455.1	NMA1037, rfaD, probable ADP-L-glycero-D-mannoheptose epimerase, len: 334 aa; similar to many e.g. SW:RFAD_ECOLI (EMBL:M33577), rfaD,Escherichia coli ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) (310 aa), fasta scores; E(): 0, 52.7% identity in 328 aa overlap. Also highly similar to TR:Q51061 (EMBL:L07845), gme, Neisseria gonorrhoeae ADP-L-glycero-D-mannoheptose epimerase (334 aa), fasta scores; E(): 0, 97.0% identity in 334 aa overlap. Similar to others from Neisseria meningitidis e.g. NMA0203, fasta scores; E(): 9.3e-10, 25.5% identity in 333 aa overlap,also similar to NMA0189 and NMA0204. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family
YP_002342456.1	NMA1038, probable type I restriction-modification system protein, len: 514 aa; similar to many e.g. SW:T1M1_ECOLI (EMBL:X13145), hsdM, Escherichia coli type I restriction enzyme protein M (EC 2.1.1.72) (520 aa), fasta scores; E(): 0, 75.8% identity in 512 aa overlap. Contains PS00092 N-6 Adenine-specific DNA methylases signature
YP_002342457.1	NMA1039,  DNA-binding protein, len: 336 aa; similar, in part, to TR:Q9Z627 (EMBL:AF106566), rhuM,Salmonella typhimurium hypothetical protein from SPI-3 pathogenicity island (215 aa), fasta scores; E(): 7.8e-28,43.9% identity in 187 aa overlap. Contains a probable helix-turn-helix motif at aa 27-48 (Score 1542, +4.44 SD)
YP_002342458.1	NMA1045, clpA, probable ATP-dependent protease ATP-binding protein, len: 759 aa; similar to many e.g. SW:CLPA_ECOLI (EMBL:M31045), clpA, Escherichia coli ATP-dependent Clp protease ATP-binding subunit (758 aa),fasta scores; E(): 0, 56.2% identity in 762 aa overlap. Similar to NMA1683, fasta scores; E(): 0, 37.2% identity in 844 aa overlap. Contains Pfam match to entry PF00495 clpA_B, Chaperonin clpA/B, PS00870 Chaperonins clpA/B signature 1, PS00871 Chaperonins clpA/B signature 2 and two PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342459.1	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA
YP_002342460.1	NMA1047, cspA, probable transcriptional regulator,len: 67 aa; similar to many cold-shock proteins e.g. SW:CSPA_ECOLI (EMBL:M30139), cspA, Escherichia coli cold shock protein (69 aa), fasta scores; E(): 1e-15, 64.5% identity in 62 aa overlap. Contains PS00352 'Cold-shock' DNA-binding domain signature
YP_002342461.1	NMA1048, len: 443 aa; unknown, similar to many e.g. SW:PMBA_ECOLI (EMBL:X54152), pmbA, Escherichia coli protein possibly involved in the control of DNA gyrase (450 aa), fasta scores; E(): 0, 50.4% identity in 425 aa overlap. Contains Pfam match to entry PF01523 PmbA_TldD, modulator of DNA gyrase
YP_002342462.1	NMA1049, len: 191 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YJGA_HAEIN (EMBL:U32794),HI1151, Haemophilus influenzae hypothetical protein (178 aa), fasta scores; E(): 9.4e-19, 36.4% identity in 176 aa overlap
YP_002342463.1	NMA1051,  membrane protein, len: 237 aa; unknown, contains probable N-terminal signal sequence and hydrophobic,  membrane-spanning region
YP_002342464.1	NMA1052, recJ, probable single-stranded-DNA-specific exonuclease, len: 566 aa; similar to many e.g. SW:RECJ_ECOLI (EMBL:M54884), recJ,Escherichia coli single-stranded-DNA-specific exonuclease (EC 3.1.-.-) (577 aa), fasta scores; E(): 0, 47.9% identity in 584 aa overlap. Contains Pfam match to entry PF01368 DHH, DHH family
YP_002342465.1	NMA1053, pcnB, probable poly(A) polymerase, len: 453 aa; similar to many e.g. SW:PCNB_ECOLI (EMBL:M20574),pcnB, Escherichia coli poly(A) polymerase (EC 2.7.7.19) (472 aa), fasta scores; E(): 0, 41.3% identity in 441 aa overlap
YP_002342466.1	NMA1054,  periplasmic protein, len: 108 aa; unknown, contains probable N-terminal signal sequence
YP_002342467.1	NMA1056, len: 317 aa; unknown, similar to many bacterial proteins of the phoH family e.g. SW:PHOL_ECOLI (EMBL:AE000170), ybeZ, Escherichia coli hypothetical protein (359 aa), fasta scores; E(): 0, 58.1% identity in 320 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342468.1	NMA1059,  periplasmic protein, len: 234 aa; unknown, contains probable N-terminal signal sequence
YP_002342469.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_002342470.1	NMA1061,  periplasmic protein, len: 138 aa; unknown, contains probable N-terminal signal sequence
YP_002342471.1	Required for efficient pilin antigenic variation
YP_002342472.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_002342473.1	NMA1064,  membrane protein, len: 209 aa; similar to SW:GC_NEIGO (EMBL:AF058711) Neisseria gonorrhoeae unknown protein (209 aa), fasta scores; E(): 0, 98.1% identity in 209 aa overlap and to bacterial hypothetical proteins. Contains hydrophobic,  membrane-spanning region
YP_002342474.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_002342475.1	NMA1066,  periplasmic protein, len: 218 aa; shows weak similarity to part of TR:O53037 (EMBL:U68399),hmcC, Haemophilus influenzae protein implicated in haemocin production (198 aa), fasta scores; E(): 4.3e-12,33.6% identity in 146 aa overlap. Also highly similar to other proteins from Neisseria meningitidis, NMA0173, fasta scores; E(): 0, 70.7% identity in 164 aa overlap and NMA0767, fasta scores; E(): 0, 88.3% identity in 128 aa overlap. Contains a probable N-terminal signal sequence
YP_002342476.1	NMA1068, len: 178 aa; unknown, lies within a region of unusually low GC content
YP_002342477.1	NMA1070, len: 66 aa; unknown, lies within a region of unusually low GC content
YP_002342478.1	NMA1071, len: 139 aa; unknown, lies within a region of unusually low GC content
YP_002342479.1	NMA1072, len: 121 aa; unknown, lies within a region of unusually low GC content
YP_002342480.1	NMA1073, len: 181 aa; unknown, similar to parts others from Neisseria meningitidis e.g. NMA1083, fasta scores; E(): 3.3e-17, 65.6% identity in 93 aa overlap,also to NMA1078. Lies within a region of unusually low GC content
YP_002342481.1	NMA1074,  membrane protein, len: 90 aa; unknown, contains hydrophobic,  membrane-spanning regions. Lies within a region of unusually low GC content
YP_002342483.1	NMA1077, len: 82 aa; unknown, lies within a region of unusually low GC content
YP_002342484.1	NMA1078, len: 122 aa; unknown, similar to parts others from Neisseria meningitidis e.g. NMA1073, fasta scores; E(): 8.4e-14, 64.6% identity in 79 aa overlap,also to NMA1083. Lies within a region of unusually low GC content
YP_002342485.1	NMA1079, len: 81 aa; unknown, lies within a region of unusually low GC content
YP_002342486.1	NMA1080, len: 38 aa; unknown, lies within a region of unusually low GC content
YP_002342487.1	NMA1081,  membrane protein, len: 95 aa; unknown, contains hydrophobic,  membrane-spanning regions, lies within a region of unusually low GC content
YP_002342488.1	NMA1082, len: 123 aa; unknown, lies within a region of unusually low GC content
YP_002342489.1	NMA1083,  periplasmic protein, len: 147 aa; unknown, similar to parts of other proteins from Neisseria meningitidis e.g. NMA1073, fasta scores; E(): 1.4e-17,65.6% identity in 93 aa overlap, also to NMA1078. Contains probable N-terminal signal sequence. Lies within a region of unusually low GC content
YP_002342490.1	NMA1084,  periplasmic protein, len: 289 aa; shows weak similarity to TR:O53036 (EMBL:U68399), hmcD,Haemophilus influenzae protein at haemocin immunity locus (297 aa), fasta scores; E(): 3.7e-07, 24.6% identity in 289 aa overlap. Similar to part of NMA0171, fasta scores; E(): 1.2e-09, 54.7% identity in 53 aa overlap. Contains probable N-terminal signal sequence
YP_002342491.1	NMA1085, len: 307 aa; similar to TR:O07166 (EMBL:Z96070) Mycobacterium tuberculosis hypothetical protein (305 aa), fasta scores; E(): 0, 42.9% identity in 282 aa overlap and shows weak similarity to many,including pseudouridine synthases. Contains Pfam match to entry PF00849 YABO, Hypothetical yabO/yceC/sfhB family
YP_002342492.1	NMA1086, len: 213 aa; shows weak similarity to TR:Q9ZD73 (EMBL:AJ235271), RP471, Rickettsia prowazekii hypothetical protein (238 aa), fasta scores; E(): 1.4e-10,30.3% identity in 198 aa overlap
YP_002342493.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
YP_002342494.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_002342495.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_002342496.1	NMA1090,  periplasmic protein, len: 612 aa; shows weak similarity to hypothetical proteins e.g. SW:YHE3_PSEAE (EMBL:X82071) Pseudomonas aeruginosa hypothetical protein (576 aa), fasta scores; E(): 1.7e-15,26.4% identity in 613 aa overlap. Contains probable N-terminal signal sequence
YP_002342497.1	Incorporates lipoproteins in the outer membrane after they are released by the LolA protein
YP_002342498.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_002342499.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_002342500.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_002342501.1	NMA1095, probable D-alanyl-D-alanine carboxypeptidase, len: 389 aa; similar to many e.g. SW:DACC_ECOLI (EMBL:X06480), dacC, Escherichia coli D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) (400 aa), fasta scores; E(): 0, 36.3% identity in 364 aa overlap. Similar to NMA0962, fasta scores; E(): 8.4e-14,29.6% identity in 243 aa overlap. Contains Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase. Contains probable N-terminal signal sequence
YP_002342502.1	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway
YP_002342503.1	NMA1097, cysA, probable sulphate permease ATP-binding protein, len: 357 aa; similar to many e.g. SW:CYSA_ECOLI (EMBL:M32101), cysA, Escherichia coli sulfate transport ATP-binding protein (365 aa), fasta scores; E(): 0, 49.4% identity in 360 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter,PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342504.1	NMA1098, cysW, probable sulphate permease inner membrane protein, len: 286 aa; similar to many e.g. SW:CYSW_ECOLI (EMBL:M32101), cysW, Escherichia coli sulfate transport system permease (291 aa), fasta scores; E(): 0, 51.7% identity in 265 aa overlap. Contains Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component and PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains hydrophobic,probable membrane-spanning regions
YP_002342505.1	NMA1100, cysU, probable sulphate permease inner membrane protein, len: 278 aa; similar to many e.g. SW:CYST_ECOLI (EMBL:M32101), cysU, Escherichia coli sulfate transport system permease (277 aa), fasta scores; E(): 0, 48.4% identity in 273 aa overlap. Contains Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component and PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains hydrophobic,probable membrane-spanning regions
YP_002342506.1	NMA1101, len: 110 aa; unknown, Glu-rich protein
YP_002342507.1	NMA1102,  integral membrane protein, len: 169 aa; similar to bacterial hypothetical proteins e.g. SW:Y318_HAEIN (EMBL:U32717), HI0318, Haemophilus influenzae (172 aa), fasta scores; E(): 0, 56.2% identity in 169 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains hydrophobic,  membrane-spanning regions. Lies within a region of unusually low GC content
YP_002342508.1	NMA1104, sodB, probable superoxide dismutase, len: 195 aa; highly similar to many e.g. SW:SODF_BORPE (EMBL:X63055), sodF, Bordetella pertussis superoxide dismutase [Fe] (EC 1.15.1.1) (192 aa), fasta scores; E(): 0, 72.9% identity in 192 aa overlap. Contains Pfam match to entry PF00081 sodfe, Iron/manganese superoxide dismutases (SODM) and PS00088 Manganese and iron superoxide dismutases signature
YP_002342509.1	unwinds double stranded DNA
YP_002342510.1	NMA1106, len: 221 aa; unknown, N-terminus is similar to the N-termini of fimbrial proteins e.g. TR:Q51528 (EMBL:L48934), fimT, Pseudomonas aeruginosa fimbrial protein (169 aa), fasta scores; E(): 0.00046,31.5% identity in 108 aa overlap. Contains N-terminal signal sequence, similar to that present in others from Neisseria meningitidis: NMA0264, NMA1110,NMA0726, NMA0424, which are all pilin-related
YP_002342511.1	NMA1107,  membrane protein, len: 204 aa; unknown, N-terminus is similar to the N-terminus of TR:Q57003 (EMBL:L36117), pilV, Pseudomonas aeruginosa gene required for type 4 fimbrial biogenesis (185 aa), fasta scores; E(): 0.00046, 25.1% identity in 183 aa overlap. Contains hydrophobic,  membrane-spanning region near the N-terminus
YP_002342512.1	NMA1108,  membrane protein, len: 332 aa; unknown, contains hydrophobic,  membrane-spanning region near the N-terminus
YP_002342513.1	NMA1109,  membrane protein, len: 197 aa; unknown, contains hydrophobic,  membrane-spanning region near the N-terminus
YP_002342514.1	NMA1110, probable pilin, len: 162 aa; similar to many e.g. SW:FMI_MORBO (EMBL:M32345) Moraxella bovis fimbrial protein I precursor (159 aa), fasta scores; E(): 6.4e-06, 28.1% identity in 153 aa overlap. Contains Pfam match to entry PF00114 pilin, Pilins (bacterial filaments) and PS00409 Prokaryotic N-terminal methylation site. Contains probable N-terminal signal sequence
YP_002342515.1	NMA1111, len: 160 aa; shows weak similarity to N-terminal regions of bacterial hypothetical proteins e.g. SW:YGAZ_ECOLI (EMBL:AE000353), ygaZ, Escherichia coli hypothetical protein (245 aa), fasta scores; E(): 1.7e-05,28.4% identity in 116 aa overlap
YP_002342516.1	catalyzes the formation of dUMP from dUTP
YP_002342517.1	catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate
YP_002342518.1	NMA1114, len: 259 aa; similar to bacterial hypothetical proteins e.g. SW:YAAA_ECOLI (EMBL:D10483),yaaA, Escherichia coli hypothetical protein (258 aa),fasta scores; E(): 0, 54.9% identity in 257 aa overlap
YP_002342519.1	NMA1115, probable transposase for IS1106A3, len: 335 aa; similar to many e.g. TR:CAB44967 (EMBL:AJ242841),Neisseria meningitidis transposase for insertion element IS1106A3 (335 aa), fasta scores; E(): 0, 97.6% identity in 335 aa overlap
YP_002342520.1	NMA1116, icd, probable isocitrate dehydrogenase,len: 741 aa; similar to many e.g. SW:IDH_AZOVI (EMBL:D73443), icd, Azotobacter vinelandii isocitrate dehydrogenase (EC 1.1.1.42) (741 aa), fasta scores; E(): 0, 65.6% identity in 735 aa overlap
YP_002342521.1	NMA1118, lst,CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3- sialyltransferase, len: 371 aa; highly similar to sialyltransferases from other strains e.g. TR:P72097 (EMBL:U60661), lst, Neisseria meningitidis strains 406Y,NRCC and 4030 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3- sialyltransferase (EC 2.4.99.-) (371 aa), fasta scores; E(): 0, 98.9% identity in 371 aa overlap
YP_002342522.1	NMA1119, probable C-type cytochrome, len: 152 aa; similar to many e.g. SW:C554_RHOSH (EMBL:L36880), cycF,Rhodobacter sphaeroides cytochrome C-554 precursor (153 aa), fasta scores; E(): 9.9e-06, 28.4% identity in 148 aa overlap. Contains Pfam match to entry PF01322 Cytochrome_C_2, Cytochrome C', PS00190 Cytochrome c family heme-binding site signature and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains a probable N-terminal signal sequence
YP_002342523.1	NMA1120, probable oxidoreductase, len: 273 aa; similar to many oxidoreductases e.g. TR:O54197 (EMBL:AJ000671), car, Streptomyces clavuligerus clavulanate-9-aldehyde reductase (247 aa), fasta scores; E(): 2.1e-23, 36.6% identity in 238 aa overlap and SW:FABG_ECOLI (EMBL:M84991), fabG, Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) (244 aa), fasta scores; E(): 1.1e-16, 32.8% identity in 201 aa overlap. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase and PS00061 Short-chain dehydrogenases/reductases family signature
YP_002342524.1	NMA1121,  acyl-CoA hydrolase, len: 148 aa; shows weak similarity to part of SW:CTE2_RAT (EMBL:U49694) Rattus norvegicus cytosolic acyl coenzyme a thioester hydrolase (EC 3.1.2.2) (338 aa), fasta scores; E(): 4.2e-07, 31.0% identity in 113 aa overlap. Also similar to hypothetical proteins e.g. SW:YCIA_HAEIN (EMBL:U32765),HI0827, Haemophilus influenzae hypothetical protein (154 aa), fasta scores; E(): 0, 62.1% identity in 132 aa overlap. Similar to NMA1691, fasta scores; E(): 1.2e-08,27.6% identity in 127 aa overlap. Contains Pfam match to entry PF01662 Acyl-CoA_hydro, Cytosolic long-chain acyl-CoA thioester hydrolase
YP_002342525.1	NMA1122, pip, probable proline iminopeptidase, len: 310 aa; similar to many e.g. SW:PIP_NEIGO (EMBL:Z25461),pip, Neisseria gonorrhoeae proline iminopeptidase (EC 3.4.11.5) (310 aa), fasta scores; E(): 0, 96.5% identity in 310 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold
YP_002342526.1	NMA1123,  lipoprotein, len: 375 aa; unknown, contains an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site and a N-terminal signal sequence
YP_002342527.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_002342528.1	NMA1126, probable transmembrane transport protein,len: 463 aa; similar to many from both prokaryotes and eukaryotes e.g. SW:UAPC_EMENI (EMBL:X79796), uapC,Emericella nidulans purine permease (580 aa), fasta scores; E(): 4.4e-22, 30.7% identity in 499 aa overlap. Also similar to hypothetical proteins e.g. SW:YGFO_ECOLI (EMBL:U28375), ygfO, Escherichia coli hypothetical protein (485 aa), fasta scores; E(): 0, 69.4% identity in 438 aa overlap. Contains Pfam match to entry PF00860 xan_ur_permease, Xanthine/uracil permeases family and PS01116 Xanthine/uracil permeases family signature. Contains hydrophobic, probable membrane-spanning regions
YP_002342529.1	NMA1127,  RNA methylase, len: 261 aa; shows weak similarity to SW:TSNR_STRAZ (EMBL:X02392), tsnR,Streptomyces azureus rRNA (adenosine-2'-O-)-methyltransferase (EC 2.1.1.66) (269 aa), blastp scores; Expect = 4.0e-14. Similar to other hypothetical RNA methylases e.g. SW:YJFH_ECOLI (EMBL:U14003), yjfH, Escherichia coli hypothetical tRNA/tRNA methyltransferase (243 aa), fasta scores; E(): 0, 52.3% identity in 241 aa overlap. Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family
YP_002342530.1	NMA1128,  membrane protein, len: 162 aa; similar to SW:YQGC_BACSU (EMBL:D84432), yqgC, Bacillus subtilis hypothetical protein (160 aa), fasta scores; E(): 3.6e-10, 34.2% identity in 161 aa overlap. Contains hydrophobic, membrane-spanning regions
YP_002342531.1	Similar to Neisseria meningitidis cytidine and deoxycytidylate deaminase family protein nmb0933 SWALL:Q9JZR1 (EMBL:AE002444) (239 aa) fasta scores: E(): 2.8e-91, 97.49% id in 239 aa, and to Bacillus subtilis hypothetical protein YaaJ yaaJ SWALL:YAAJ_BACSU (SWALL:P21335) (161 aa) fasta scores: E(): 9e-21, 40.66% id in 150 aa; NMA1129,  cytosine deaminase, len: 239 aa; shows weak similarity to many e.g. SW:FCA1_CANAL (EMBL:U55194), fca1, Candida albicans cytosine deaminase (EC 3.5.4.1) (150 aa), fasta scores; E(): 5.5e-08, 31.4% identity in 140 aa overlap. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region and PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature
YP_002342532.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_002342534.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_002342535.1	NMA1134,  lipoprotein, len: 281 aa; unknown, contains appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site and probable N-terminal signal sequence
YP_002342536.1	NMA1135, len: 193 aa; unknown, shows weak similarity to parts of hypothetical proteins e.g. TR:O32813 (EMBL:U80599) Lactococcus lactis hypothetical protein (207 aa), fasta scores; E(): 0.001, 25.6% identity in 121 aa overlap
YP_002342537.1	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine
YP_002342538.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif
YP_002342539.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002342540.1	MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor
YP_002342541.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_002342542.1	NMA1141,  redoxin, len: 245 aa; similar to many from both bacteria and eukaryotes e.g. TR:AAD28242 (EMBL:AF121355) Arabidopsis thaliana peroxiredoxin (162 aa), fasta scores; E(): 2e-17, 39.9% identity in 158 aa overlap. Contains Pfam match to entry PF00578 AhpC-TSA,AhpC/TSA family
YP_002342543.1	Catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002342544.1	NMA1143, sdhC, probable succinate dehydrogenase cytochrome B subunit, len: 125 aa; similar to many e.g. SW:DHSC_ECOLI (EMBL:J01619), sdhC, Escherichia coli succinate dehydrogenase cytochrome B-556 subunit (129 aa),fasta scores; E(): 1.4e-14, 39.8% identity in 123 aa overlap. Contains Pfam match to entry PF01127 Sdh_cyt,Succinate dehydrogenase cytochrome b subunit and PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. Contains hydrophobic, probable membrane-spanning regions
YP_002342545.1	NMA1144, sdhD, probable succinate dehydrogenase hydrophobic membrane anchor protein, len: 113 aa; similar to SW:DHSD_ECOLI (EMBL:J01619), sdhD, Escherichia coli succinate dehydrogenase hydrophobic membrane anchor protein (115 aa), fasta scores; E(): 5e-13, 36.5% identity in 104 aa overlap. Also similar to TR:O83000 (EMBL:AB015757) Rhodoferax fermentans fumarate reductase cytochrome B small subunit (121 aa), fasta scores; E(): 1.8e-21, 48.6% identity in 111 aa overlap. Contains hydrophobic, probable membrane-spanning regions
YP_002342546.1	NMA1145, sdhA, probable succinate dehydrogenase flavoprotein subunit, len: 587 aa; similar to many e.g. SW:DHSA_ECOLI (EMBL:J01619), sdhA, Escherichia coli succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) (588 aa), fasta scores; E(): 0, 56.6% identity in 590 aa overlap. Also similar to TR:O83001 (EMBL:AB015757) Rhodoferax fermentans fumarate reductase flavoprotein subunit (601 aa), fasta scores; E(): 0, 64.2% identity in 592 aa overlap. Similar to NMA2092, fasta scores; E(): 8.6e-31, 33.9% identity in 546 aa overlap. Contains Pfam match to entry PF00890 FAD_binding_2, FAD binding domain and PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site
YP_002342547.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_002342548.1	NMA1147, len: 82 aa; shows weak similarity to bacterial hypothetical proteins e.g. TR:Q9ZCV9 (EMBL:AJ235272), RP599, Rickettsia prowazekii hypothetical protein (87 aa), fasta scores; E(): 0.00085, 30.7% identity in 75 aa overlap
YP_002342549.1	type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH
YP_002342550.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_002342551.1	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA
YP_002342552.1	E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002342553.1	NMA1152,  membrane protein, len: 95 aa; unknown, contains hydrophobic,  membrane-spanning regions and a N-terminal signal sequence
YP_002342554.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_002342555.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
YP_002342556.1	NMA1155, len: 120 aa; unknown, shows similarity to parts of hypothetical proteins e.g. SW:YAFM_HAEIN (EMBL:U32706), HI0217, Haemophilus influenzae hypothetical protein (176 aa), fasta scores; E(): 2.6e-15, 42.5% identity in 106 aa overlap. Similar to parts of NMA1675,fasta scores; E(): 8.4e-07, 42.7% identity in 103 aa overlap and NMA0532, fasta scores; E(): 8.4e-07, 42.7% identity in 103 aa overlap
YP_002342557.1	NMA1156, len: 76 aa; unknown, lysine-rich
YP_002342558.1	NMA1157, len: 265 aa; unknown, lies within a region of unusually low GC content
YP_002342559.1	NMA1158, len: 62 aa; unknown, lies within a region of unusually low GC content
YP_002342560.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_002342561.1	catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_002342562.1	NMA1161, probable outer-membrane receptor protein,len: 764 aa; shows weak similarity to many outer-membrane receptors e.g. TR:O68881 (EMBL:AF055999), phuR,Pseudomonas aeruginosa outer membrane hemin receptor (764 aa), fasta scores; E(): 5.3e-09, 22.5% identity in 746 aa overlap and TR:P72121 (EMBL:D28119) Pseudomonas aeruginosa outer membrane protein C precursor (723 aa), fasta scores; E(): 0.00075, 21.0% identity in 794 aa overlap. Similar to NMA0474, fasta scores; E(): 2e-05, 20.8% identity in 795 aa overlap. Contains probable N-terminal signal sequence
YP_002342563.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
YP_002342564.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002342565.1	NMA1167,  phage protein, len: 344 aa; shows weak similarity to e.g. TR:O34630 (EMBL:U83796), rstA2,Vibrio cholerae bacteriophage CTXphi protein required for replication and integration (359 aa), fasta scores; E(): 1.5e-09, 27.8% identity in 223 aa overlap. Also similar to TR:O82959 (EMBL:AB015669) ORF C7 from Burkholderia solanacearum plasmid pJTPS1 (444 aa), fasta scores; E(): 1.4e-16, 33.9% identity in 239 aa overlap. Highly similar to others from Neisseria meningitidis, NMA1999, E(): 0,100.0% identity in 344 aa overlap, NMA0782, fasta scores; E(): 0, 42.7% identity in 337 aa overlap, and NMA1792,fasta scores; E(): 0, 43.3% identity in 298 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342566.1	NMA1168, len: 114 aa; unknown, similar to others from Neisseria meningitidis, NMA2000, fasta scores; E(): 0, 100.0% identity in 114 aa overlap, NMA1793, fasta scores; E(): 1.6e-13, 37.8% identity in 98 aa overlap and NMA0781, fasta scores; E(): 2.3e-10, 34.9% identity in 83 aa overlap
YP_002342567.1	NMA1169, len: 65 aa; unknown, similar to others from Neisseria meningitidis, NMA2001, fasta scores; E(): 4.2e-27, 100.0% identity in 65 aa overlap, NMA1794, fasta scores; E(): 4.6e-07, 38.3% identity in 60 aa overlap and NMA0780, fasta scores; E(): 1.3e-06, 36.1% identity in 61 aa overlap
YP_002342568.1	NMA1170,  integral membrane protein, len: 94 aa; unknown, similar to others from Neisseria meningitidis, NMA2002, fasta scores; E(): 0, 100.0% identity in 94 aa overlap. Contains hydrophobic,  membrane-spanning regions, NMA1170, fasta scores; E(): 0,100.0% identity in 94 aa overlap and NMA0779, fasta scores; E(): 1.5e-18, 72.2% identity in 72 aa overlap
YP_002342569.1	NMA1171, len: 92 aa; unknown, similar to others from Neisseria meningitidis, NMA2003, fasta scores; E(): 0, 100.0% identity in 92 aa overlap, NMA0778, fasta scores; (): 1.5e-25, 58.7% identity in 92 aa overlap and NMA1796, fasta scores; E(): 8.4e-09, 32.3% identity in 93 aa overlap. C-terminus is hydrophobic
YP_002342570.1	NMA1172, len: 105 aa; similar to others from Neisseria meningitidis e.g. TR:O87782 (EMBL:AJ010115) Neisseria meningitidis strain B:15:P1.16 hypothetical protein (fragment) (148 aa), fasta scores; E(): 0, 83.8% identity in 105 aa overlap. Also similar to NMA2004, fasta scores; E(): 4e-25 54.8% identity in 104 aa overlap and NMA0777, fasta scores; E(): 6.7e-16, 57.5% identity in 73 aa overlap. Lies within a region of unusually low GC content
YP_002342571.1	NMA1173, probable cell-surface protein, len: 146 aa; highly similar to the N-terminus of TR:O87783 (EMBL:AJ010115), tspB, Neisseria meningitidis strain B:15:P1.16 T-cell and B-cell antigen (partial CDS) (504 aa), fasta scores; E(): 5.9e-29, 68.2% identity in 129 aa overlap. Similar to others from Neisseria meningitidis,e.g. NMA0776, fasta scores; E(): 1.8e-23, 51.0% identity in 145 aa overlap, and NMA1797, fasta scores; E(): 1.8e-23, 51.0% identity in 145 aa overlap (both tspB genes) and NMA2005 (another  cell-surface protein), fasta scores, E(): 1.2e-30, 66.2% identity in 133 aa overlap. N-terminal half has low GC content. Contains a probable N-terminal signal sequence
YP_002342572.1	NMA1174, len: 155 aa; unknown, similar, except at the N-terminus, to SW:MDAB_ECOLI (EMBL:U18656), mdaB,Escherichia coli modulator of drug activity B ( modulator of topoisomerase IV activity imparting DMP 840,adriamycin and etoposide resistance on overexpression) (193 aa), fasta scores; E(): 0, 63.7% identity in 146 aa overlap. Also similar to hypothetical proteins from bacteria and Schizosaccharomyces pombe e.g. SW:YA05_SCHPO (EMBL:Z49811), SPAC5H10.05C, Schizosaccharomyces pombe hypothetical protein (196 aa), fasta scores; E(): 0, 55.1% identity in 147 aa overlap. Identical, except at the N-terminus, to NMA0600, fasta scores; E(): 0, 99.3% identity in 147 aa overlap
YP_002342573.1	catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme
YP_002342574.1	NMA1176,  membrane protein, len: 127 aa; unknown, contains hydrophobic,  membrane-spanning regions
YP_002342575.1	forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
YP_002342576.1	NMA1179, serB, probable phosphoserine phosphatase,len: 277 aa; similar, except at N-terminus, to many e.g. SW:SERB_ECOLI (EMBL:X03046), serB, Escherichia coli phosphoserine phosphatase (EC 3.1.3.3) (322 aa), fasta scores; E(): 8.4e-30, 45.7% identity in 234 aa overlap
YP_002342577.1	involved in de novo purine biosynthesis
YP_002342578.1	NMA1185, probable transposase, len: 318 aa; similar to many e.g. TR:Q51474 (EMBL:M24471) Alteromonas atlantica CDS within insertion element IS492 which is involved in reversible inactivation of extracellular polysaccharide production (318 aa), fasta scores; E(): 1.3e-28, 33.9% identity in 301 aa overlap. Also shows weak similarity to pilin-inverting genes e.g. SW:PIV_MORLA (EMBL:M34367),piv, Moraxella lacunata pilin gene inverting protein (322 aa), fasta scores; E(): 8.5e-14, 30.4% identity in 313 aa overlap. Highly similar to others from Neisseria meningitidis e.g. NMA0733, fasta scores; E(): 0, 94.3% identity in 279 aa overlap, also NMA2085. Contains Pfam match to entry PF01548 Transposase_9, Transposase
YP_002342579.1	NMA1186, len: 164 aa; unknown, similar to part of TR:Q38494 (EMBL:M64097) bacteriophage Mu protein E16 (195 aa), fasta scores; E(): 2.7e-05, 46.7% identity in 60 aa overlap. Identical to NMA1301 and similar to NMA1867,fasta scores; E(): 1.5e-25, 55.5% identity in 137 aa overlap
YP_002342580.1	NMA1187, len: 142 aa; unknown, identical to NMA1302 and similar to NMA1866, fasta scores; E(): 2.4e-10, 29.7% identity in 145 aa overlap
YP_002342581.1	NMA1188,  amidase, len: 181 aa; shows very weak similarity to TR:P89923 (EMBL:Y11476), ply12,Bacteriophage 12826 N-acetylmuramoyl-L-alanine amidase endolysin (EC 3.5.1.28) (257 aa), fasta scores; E(): 0.16,26.0% identity in 177 aa overlap and to bacterial amidases (some ) e.g. TR:O32421 (EMBL:D76414), lytH,Staphylococcus aureus N-acetylmuramoyl-L-alanine amidase (291 aa), fasta scores; E(): 0.0093, 25.8% identity in 182 aa overlap. Identical to NMA1303 and highly similar to NMA1865, fasta scores, E(): 0, 96.7% identity in 181 aa overlap
YP_002342582.1	NMA1189, len: 54 aa; unknown, identical to NMA1304 and NMA1863
YP_002342583.1	NMA1190, len: 78 aa; unknown, identical to NMA1305 and NMA1862
YP_002342584.1	NMA1191, len: 139 aa; unknown, highly similar to NMA1306, fasta scores; E(): 0, 97.1% identity in 139 aa overlap and NMA1861, fasta scores; E(): 0, 97.1% identity in 139 aa overlap
YP_002342585.1	NMA1192, len: 60 aa; unknown, highly similar to NMA1860, fasta scores; E(): 7.9e-26, 98.3% identity in 60 aa overlap and to part of NMA1307, fasta scores; E(): 6.8e-09, 82.8% identity in 29 aa overlap
YP_002342586.1	NMA1193, len: 56 aa; unknown, identical to NMA1859
YP_002342587.1	NMA1194, len: 72 aa; unknown, identical to NMA1858
YP_002342588.1	NMA1195, len: 112 aa; unknown, highly similar to part of NMA1308, fasta scores; E(): 2e-20, 84.4% identity in 64 aa overlap and similar to part of NMA1857, fasta scores; E(): 7.2e-17, 47.3% identity in 112 aa overlap
YP_002342589.1	NMA1196, len: 88 aa; unknown, highly similar to NMA1310, fasta scores; E(): 6.8e-34, 94.3% identity in 88 aa overlap and similar to NMA1856, fasta scores; E(): 3.5e-11, 45.2% identity in 84 aa overlap
YP_002342590.1	NMA1197, len: 65 aa; unknown, similar to NMA1311,fasta scores; E(): 8.2e-14, 56.3% identity in 64 aa overlap and NMA1855, fasta scores; E(): 3.2e-09, 45.5% identity in 66 aa overlap
YP_002342591.1	NMA1198,  DNA-binding protein, len: 168 aa; highly similar to NMA1312, fasta scores; E(): 0, 73.7% identity in 167 aa overlap and NMA1854, fasta scores; E(): 0, 69.0% identity in 168 aa overlap. Contains probable helix-turn-helix motif at aa 21-42 (Score 1161, +3.14 SD)
YP_002342592.1	NMA1199, probable transposase for IS1106A3, len: 335 aa; similar to many e.g. TR:CAB44967 (EMBL:AJ242841),Neisseria meningitidis transposase for insertion sequence IS1106A3 (335 aa), fasta scores; E(): 0, 97.3% identity in 335 aa overlap
YP_002342593.1	NMA1200, probable surface fibril protein, len: 529 aa; similar to the N-terminal regions of TR:Q48152 (EMBL:U38617), hia, Haemophilus influenzae adhesin (1098 aa), fasta scores; E(): 0, 44.0% identity in 627 aa overlap and TR:P71401 (EMBL:U41852), hsf, Haemophilus influenzae type B surface fibril protein (2353 aa), fasta scores; E(): 0, 47.8% identity in 584 aa overlap
YP_002342594.1	NMA1201, probable rubredoxin, len: 56 aa; similar to many e.g. SW:RUBR_ACICA (EMBL:Z46863) Acinetobacter calcoaceticus rubredoxin involved in the hydrocarbon hydroxylating system (54 aa), fasta scores; E(): 1.6e-13,64.2% identity in 53 aa overlap. Contains Pfam match to entry PF00301 rubredoxin, Rubredoxins and PS00202 Rubredoxin signature
YP_002342595.1	NMA1202, probable acyl-CoA dehydrogenase, len: 363 aa; shows weak similarity to many e.g. SW:IVD_HUMAN (EMBL:M34192), ivd, Homo sapiens isovaleryl-CoA dehydrogenase precursor (EC 1.3.99.10) (423 aa), fasta scores; E(): 2.7e-10, 24.0% identity in 358 aa overlap. Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase
YP_002342596.1	NMA1203, len: 182 aa; shows weak similarity to TR:Q53427 (EMBL:S71704), mip, Legionella pneumophila macrophage infectivity potentiator protein (184 aa), fasta scores; E(): 2.9e-08, 26.9% identity in 175 aa overlap
YP_002342597.1	NMA1204, len: 123 aa; unknown
YP_002342598.1	component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent
YP_002342599.1	NMA1206, probable oxidoreductase, len: 1277 aa; the N-terminal half shows weak similarity to several oxidoreductases e.g. TR:Q9ZLW7 (EMBL:AE001480), glcD,Helicobacter pylori J99  glycolate oxidase (459 aa), fasta scores; E(): 1.5e-09, 24.8% identity in 455 aa overlap. The C-terminal half shows weak similarity to iron-sulphur proteins e.g. TR:O67558 (EMBL:AE000748), glpC, Aquifex aeolicus oxido/reductase iron sulfur protein (395 aa), fasta scores; E(): 5.2e-07,22.8% identity in 465 aa overlap. Contains Pfam matches to entry PF01565 FAD_binding_4, FAD binding domain and to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains. Contains PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature
YP_002342600.1	NMA1207, len: 333 aa; similar to many hypothetical proteins e.g. TR:O68273 (EMBL:AF026544) Alcaligenes eutrophus hypothetical protein (322 aa), fasta scores; E(): 0, 47.3% identity in 315 aa overlap. Also similar to SW:NIR3_RHOCA (EMBL:X72382), nifR3, Rhodobacter capsulatus nitrogen regulation protein (not stringently required for nitrogen fixation) (324 aa), fasta scores; E(): 8.1e-19,31.5% identity in 324 aa overlap. Similar to NMA1633,fasta scores; E(): 8.3e-20, 34.0% identity in 244 aa overlap. Contains Pfam match to entry PF01207 UPF0034,Uncharacterized protein family UPF0034 and PS01136 Uncharacterized protein family UPF0034 signature
YP_002342601.1	NMA1209, len: 30 aa; unknown
YP_002342602.1	NMA1210, len: 102 aa; unknown
YP_002342603.1	NMA1211, len: 171 aa; unknown
YP_002342604.1	NMA1214, len: 38 aa; unknown
YP_002342605.1	NMA1215, len: 57 aa; similar to parts of hypothetical proteins from bacteriophage and bacteria e.g. SW:YO14_BPHP1 (EMBL:U24159) bacteriophage HP1 hypothetical protein (133 aa), fasta scores; E(): 3e-07, 37.5% identity in 56 aa overlap
YP_002342606.1	NMA1216, len: 71 aa; unknown
YP_002342607.1	NMA1217, probable transposase for IS1106A3, len: 294 aa; highly similar to many e.g. TR:CAB44967 (EMBL:AJ242841) Neisseria meningitidis transposase for insertion sequence IS1106A3 (335 aa), fasta scores; E(): 0, 79.4% identity in 335 aa overlap. The difference in length with respect to TR:CAB44967 is accounted for by a deletion from within the C-terminal region of NMA1217
YP_002342608.1	NMA1221,  phage integrase, len: 191 aa; similar to the C-terminal half of phage integrases e.g. SW:INTA_ECOLI (EMBL:U03737), intA, Escherichia coli prophage CP4-57 integrase (413 aa), fasta scores; E(): 3.1e-06, 30.3% identity in 165 aa overlap
YP_002342609.1	NMA1222, len: 291 aa; unknown
YP_002342610.1	NMA1223, len: 96 aa; unknown
YP_002342611.1	NMA1225,  phage repressor, len: 125 aa; shows weak similarity to SW:RPC_BPPH1 (EMBL:X02799) Bacteriophage phi-105 immunity repressor protein (144 aa),fasta scores; E(): 0.0068, 36.3% identity in 80 aa overlap and to  phage repressors. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and probable helix-turn-helix motif at aa 21-42 (Score 1857, +5.51 SD). Lies within a region of unusually low GC content
YP_002342612.1	NMA1226, len: 81 aa; unknown, lies within a region of unusually low GC content
YP_002342613.1	NMA1227, len: 30 aa; unknown, lies within a region of unusually low GC content
YP_002342614.1	NMA1228, len: 322 aa; unknown, lies within a region of unusually low GC content
YP_002342615.1	NMA1229,  membrane protein, len: 160 aa; unknown, contains a  N-terminal signal sequence and hydrophobic, membrane-spanning regions. Lies within a region of unusually low GC content
YP_002342616.1	NMA1230, len: 167 aa; unknown
YP_002342617.1	NMA1233, len: 136 aa; similar to part of TR:Q50995 (EMBL:L36381) Neisseria gonorrhoeae hypothetical protein (172 aa), fasta scores; E(): 9.1e-15, 61.2% identity in 98 aa overlap
YP_002342618.1	NMA1234,  transposase, len: 249 aa; similar to many e.g. SW:T150_ECOLI (EMBL:X07037) Escherichia coli transposase for insertion sequence IS150 (283 aa), fasta scores; E(): 0, 43.7% identity in 263 aa overlap. Also highly similar to TR:Q50996 (EMBL:L36381) Neisseria gonorrhoeae hypothetical protein (267 aa), fasta scores; E(): 0, 73.4% identity in 267 aa overlap
YP_002342619.1	NMA1237, len: 201 aa; similar to bacterial hypothetical proteins e.g. SW:YFCN_ECOLI (EMBL:AE000321),yfcN, Escherichia coli hypothetical protein (183 aa),fasta scores; E(): 3.1e-06, 27.5% identity in 178 aa overlap
YP_002342620.1	NMA1243, probable sulphate-binding protein, len: 351 aa; similar to many e.g. SW:SUBI_ECOLI (EMBL:X02519),sbp, Escherichia coli sulfate-binding protein precursor (329 aa), fasta scores; E(): 0, 49.1% identity in 316 aa overlap. Contains Pfam match to entry PF01100 Sulphate_bind, Prokaryotic sulphate- and thiosulphate-binding protein and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains a probable N-terminal signal sequence
YP_002342621.1	NMA1244, len: 160 aa; similar to TR:P72792 (EMBL:D90900) Synechocystis sp. (strain PCC 6803) hypothetical protein (160 aa), fasta scores; E(): 1.1e-05,28.8% identity in 160 aa overlap. Shows very weak similarity (not statistically significant) to eukaryotic acetyltransferases e.g. SW:ATDA_MOUSE (EMBL:L10244), sat,Mus musculus diamine acetyltransferase (EC 2.3.1.57) (171 aa), fasta scores; E(): 1, 24.8% identity in 137 aa overlap. Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family
YP_002342622.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_002342623.1	NMA1246, len: 181 aa; unknown, previously sequenced from Neisseria meningitidis Z2491 as TR:CAB44974 (EMBL:AJ242841). Lies within a region of unusually low GC content
YP_002342624.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_002342625.1	NMA1248,  periplasmic protein, len: 121 aa; previously sequenced from Neisseria meningitidis Z2491 as TR:CAB44972 (EMBL:AJ242841). Contains  N-terminal signal sequence
YP_002342626.1	NMA1249, abcZ, probable ABC transporter ATP-binding protein, len: 636 aa; previously sequenced from Neisseria meningitidis Z2491 as TR:CAB44971 (EMBL:AJ242841). Similar to many e.g. SW:TLRC_STRFR (EMBL:M57437), tlrC,Streptomyces fradiae tylosin resistance ATP-binding protein (548 aa), blastp score; Expect = 1.5e-53 and SW:UUP_ECOLI (EMBL:AE000197), uup, Escherichia coli  ABC transporter ATP-binding protein (635 aa),fasta scores; E(): 0, 47.2% identity in 634 aa overlap. . Similar to many others in Neisseria meningitidis,particularly NMA2101, fasta scores; E(): 0, 39.3% identity in 539 aa overlap. Contains two Pfam matches to entry PF00005 ABC_tran, ABC transporter, two PS00211 ABC transporters family signature and two PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342627.1	NMA1250, dedA, hypothetical protein, len: 214 aa; previously sequenced from Neisseria meningitidis Z2491 as TR:CAB44970 (EMBL:AJ242841), but with a different predicted start codon. Similar to many e.g. SW:DEDA_ECOLI (EMBL:M68934), dedA, Escherichia coli dedA protein Ded A protein (219 aa), fasta scores; E(): 0, 68.0% identity in 206 aa overlap. Contains Pfam match to entry PF00597 DedA,DedA family
YP_002342628.1	NMA1251, opcA, outer membrane protein precursor,len: 272 aa; previously sequenced from Neisseria meningitidis Z2491 as TR:CAB44969 (EMBL:AJ242841). C-terminus is similar to NMA2183, fasta scores; E(): 1e-05, 29.2% identity in 89 aa overlap. Contains an N-terminal signal sequence
YP_002342629.1	NMA1253, probable transposase for IS1106A3, len: 335 aa; previously sequenced as TR:CAB44967 (EMBL:AJ242841)
YP_002342630.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_002342631.1	NMA1255, ggt, probable gamma-glutamyltranspeptidase, len: 591 aa; similar to many e.g. SW:GGT_BACSU (EMBL:U49358), ggt, Bacillus subtilis gamma-glutamyltranspeptidase precursor (EC 2.3.2.2) (587 aa), fasta scores; E(): 0, 38.2% identity in 573 aa overlap. Contains Pfam match to entry PF01019 G_glu_transpept, Gamma-glutamyltranspeptidase and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains a probable N-terminal signal sequence
YP_002342632.1	NMA1257, len: 75 aa; unknown
YP_002342633.1	NMA1258, len: 72 aa; similar to hypothetical proteins TR:Q9ZJY4 (EMBL:AE001544) Helicobacter pylori J99 hypothetical protein (76 aa), fasta scores; E(): 1.1e-06,47.0% identity in 66 aa overlap and TR:O25839 (EMBL:AE000629) Helicobacter pylori 26695 hypothetical protein (76 aa), fasta scores; E(): 1.3e-06, 45.5% identity in 66 aa overlap
YP_002342634.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
YP_002342635.1	NMA1260, len: 281 aa; unknown, similar to SW:YHIR_ECOLI (EMBL:U00039), yhiR, Escherichia coli hypothetical protein (280 aa), fasta scores; E(): 0, 42.3% identity in 274 aa overlap and SW:YHIR_HAEIN (EMBL:M62809), HI0441, Haemophilus influenzae hypothetical protein (281 aa), fasta scores; E(): 0, 41.9% identity in 272 aa overlap
YP_002342636.1	NMA1261,  integral membrane protein, len: 200 aa; similar to many bacterial hypothetical proteins e.g. SW:YGIH_ECOLI (EMBL:U28379), ygiH, Escherichia coli hypothetical protein (205 aa), fasta scores; E(): 7.8e-26,43.5% identity in 193 aa overlap. Contains hydrophobic, membrane-spanning regions
YP_002342637.1	NMA1262, folB, probable dihydroneopterin aldolase,len: 118 aa; similar to many e.g. SW:FOLB_BACSU (EMBL:M34053), folB, Bacillus subtilis dihydroneopterin aldolase (EC 4.1.2.25) (120 aa), fasta scores; E(): 3.5e-07, 35.3% identity in 119 aa overlap and SW:FOLB_ECOLI (EMBL:U28379), folB, Escherichia coli probable dihydroneopterin aldolase (122 aa), fasta scores; E(): 9.2e-15, 40.0% identity in 115 aa overlap
YP_002342638.1	NMA1263, len: 178 aa; unknown, similar to many bacterial hypothetical proteins e.g. SW:YQKG_BACSU (EMBL:D84432), yqkG, Bacillus subtilis hypothetical protein (185 aa), fasta scores; E(): 6.9e-21, 37.9% identity in 177 aa overlap. Contains Pfam match to entry PF00293 mutT, Bacterial mutT protein
YP_002342639.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_002342640.1	NMA1265, probable integral membrane protein, len: 226 aa; unknown, contains hydrophobic, probable membrane-spanning regions
YP_002342641.1	NMA1266,  cell-division protein, len: 1014 aa; similar to many e.g. SW:FTSK_ECOLI (EMBL:Z49932),ftsK, Escherichia coli cell division protein (1329 aa),fasta scores; E(): 0, 40.0% identity in 1015 aa overlap,the E.coli protein being approx. 300 aa longer at the N-terminus. Note that this means most of the predicted membrane spans in the E.coli homologue are absent from this protein. Similar over the C-terminal approx. 500 aa to NMA1527, fasta scores; E(): 0, 57.9% identity in 556 aa overlap. Contains Pfam match to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family and PS00017 ATP/GTP-binding site motif A (P-loop). Contains a probable N-terminal signal sequence and a hydrophobic, probable membrane-spanning region
YP_002342642.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_002342643.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_002342644.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_002342645.1	NMA1272, len: 220 aa; unknown, shows weak similarity to SW:YECA_ECOLI (EMBL:AE000284), yecA,Escherichia coli hypothetical protein (221 aa), fasta scores; E(): 5.5e-12, 27.2% identity in 228 aa overlap
YP_002342646.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_002342647.1	NMA1274, len: 376 aa; unknown, similar to SW:YPG2_ZYMMO (EMBL:L09649), zm2, Zymomonas mobilis hypothetical protein (380 aa), fasta scores; E(): 0, 47.1% identity in 374 aa overlap. Also similar to parts of Caenorhabditis elegans hypothetical proteins e.g. TR:O76373 (EMBL:AF067618), F56H1.5, Caenorhabditis elegans hypothetical protein (1192 aa), fasta scores; E(): 5e-11,27.1% identity in 317 aa overlap. Contains Pfam match to entry PF00246 Zn_carbOpept, Zinc carboxypeptidase
YP_002342648.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_002342649.1	NMA1278, len: 222 aa; unknown, similar to bacterial hypothetical proteins e.g. TR:O33611 (EMBL:AB004855) Streptomyces cyaneus protein possibly involved in morphological differentiation (277 aa), fasta scores; E(): 1.5e-15, 29.1% identity in 227 aa overlap and TR:O69629 (EMBL:AL022121) Mycobacterium tuberculosis hypothetical protein (287 aa), fasta scores; E(): 2.1e-15, 30.2% identity in 222 aa overlap
YP_002342650.1	NMA1279, len: 243 aa; similar to SW:YFGE_ECOLI (EMBL:AE000336), yfgE, Escherichia coli hypothetical protein (248 aa), fasta scores; E(): 3.2e-19, 31.3% identity in 230 aa overlap and SW:YFGE_HAEIN (EMBL:U32802), HI1225.1, Haemophilus influenzae hypothetical protein (231 aa), fasta scores; E(): 5.8e-17,30.1% identity in 226 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop), which may be fortuitous
YP_002342651.1	NMA1281, len: 61 aa; unknown
YP_002342652.1	NMA1282,  DNA-binding protein, len: 293 aa; unknown, contains probable helix-turn-helix at aa 42-63 (Score 1152, +3.11 SD)
YP_002342653.1	NMA1283, len: 83 aa; unknown
YP_002342654.1	NMA1284,  phage transposase, len: 657 aa; similar to TR:Q38013 (EMBL:X87627) Bacteriophage D3112 transposase A (690 aa), fasta scores; E(): 0, 34.0% identity in 623 aa overlap. Similar to NMA1882, fasta scores; E(): 0, 41.3% identity in 656 aa overlap. Contains Pfam match to entry PF00552 integrase, Integrase and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342655.1	NMA1287, len: 88 aa; unknown, similar to part of NMA1880, fasta scores; E(): 0.0086, 36.5% identity in 63 aa overlap
YP_002342656.1	NMA1288, len: 39 aa; unknown
YP_002342657.1	NMA1289, len: 40 aa; unknown
YP_002342658.1	NMA1290, len: 55 aa; unknown
YP_002342659.1	NMA1291, gam, probable host-nuclease inhibitor protein, len: 172 aa; similar to several e.g. SW:VGAM_BPMU (EMBL:X04390), gam, Bacteriophage Mu host-nuclease inhibitor protein (174 aa), fasta scores; E(): 3.9e-24,46.8% identity in 173 aa overlap
YP_002342660.1	NMA1292, len: 71 aa; unknown
YP_002342661.1	NMA1293,  phage anti-repressor protein,len: 202 aa; similar to several e.g. TR:Q38585 (EMBL:X95646), ant, Streptococcus thermophilus bacteriophage Sfi21 anti-repressor protein (287 aa), fasta scores; E(): 6.5e-07, 31.3% identity in 134 aa overlap and TR:AAD25485 (EMBL:AF125520), L0142, bacteriophage 933W hypothetical protein (209 aa), fasta scores; E(): 2.7e-17,37.8% identity in 201 aa overlap
YP_002342662.1	NMA1294, len: 66 aa; unknown, similar to NMA1297,fasta scores; E(): 1.4e-08, 43.9% identity in 57 aa overlap and NMA1295, fasta scores; E(): 7.1e-07, 51.1% identity in 47 aa overlap
YP_002342663.1	NMA1295, len: 61 aa; unknown, similar to NMA1297,fasta scores; E(): 2.7e-09, 53.8% identity in 52 aa overlap and NMA1294, fasta scores; E(): 4.1e-06, 51.1% identity in 47 aa overlap
YP_002342664.1	NMA1296, len: 33 aa; unknown
YP_002342665.1	NMA1297, len: 55 aa; unknown, similar to NMA1295,fasta scores; E(): 1.9e-10, 53.8% identity in 52 aa overlap and NMA1294, fasta scores; E(): 1.1e-08, 43.9% identity in 57 aa overlap
YP_002342666.1	NMA1298, len: 60 aa; unknown
YP_002342667.1	NMA1299, len: 63 aa; unknown
YP_002342668.1	NMA1300,  membrane protein, len: 138 aa; unknown, contains hydrophobic,  membrane-spanning regions
YP_002342669.1	NMA1301, len: 164 aa; unknown, similar to part of TR:Q38494 (EMBL:M64097) bacteriophage Mu protein E16 (195 aa), fasta scores; E(): 2.7e-05, 46.7% identity in 60 aa overlap. Identical to NMA1186 and similar to NMA1867,fasta scores; E(): 1.5e-25, 55.5% identity in 137 aa overlap
YP_002342670.1	NMA1302, len: 142 aa; unknown, identical to NMA1187 and similar to NMA1866, fasta scores; E(): 1.8e-10, 29.7% identity in 145 aa overlap
YP_002342671.1	NMA1303,  amidase, len: 181 aa; shows very weak similarity to TR:P89923 (EMBL:Y11476), ply12,Bacteriophage 12826 N-acetylmuramoyl-L-alanine amidase endolysin (EC 3.5.1.28) (257 aa), fasta scores; E(): 0.16,26.0% identity in 177 aa overlap and to bacterial amidases (some ) e.g. TR:O32421 (EMBL:D76414), lytH,Staphylococcus aureus N-acetylmuramoyl-L-alanine amidase (291 aa), fasta scores; E(): 0.0093, 25.8% identity in 182 aa overlap. identical to NMA1188 and highly similar to NMA1864, fasta scores; E(): 0, 96.7% identity in 181 aa overlap
YP_002342672.1	NMA1304, len: 54 aa; unknown, identical to NMA1189 and NMA1863
YP_002342673.1	NMA1305, len: 78 aa; unknown, identical to NMA1190 and NMA1862
YP_002342674.1	NMA1306, len: 139 aa; unknown, identical to NMA1861 and highly similar to NMA1191, fasta scores; E(): 0, 97.1% identity in 139 aa overlap
YP_002342675.1	NMA1307, len: 64 aa; unknown, highly similar to NMA1192, fasta scores; E(): 1.9e-11, 82.8% identity in 29 aa overlap and NMA1860, fasta scores; E(): 1.9e-11, 82.8% identity in 29 aa overlap
YP_002342676.1	NMA1308, len: 70 aa; unknown, highly similar to NMA1195, fasta scores; E(): 3.3e-24, 84.4% identity in 64 aa overlap and NMA1157, fasta scores; E(): 1.7e-11, 47.5% identity in 61 aa overlap
YP_002342677.1	NMA1309, len: 39 aa; unknown, similar to NMA1195,fasta scores; E(): 6.1e-08, 65.7% identity in 35 aa overlap and NMA1857, fasta scores; E(): 0.036, 42.9% identity in 35 aa overlap
YP_002342678.1	NMA1310, len: 88 aa; unknown, highly similar to NMA1196, fasta scores; E(): 3.9e-33, 94.3% identity in 88 aa overlap and similar to NMA1156, fasta scores; E(): 1.5e-10, 44.0% identity in 84 aa overlap
YP_002342679.1	NMA1311, len: 65 aa; unknown, similar to NMA1197,fasta scores; E(): 1.1e-14, 56.3% identity in 64 aa overlap and NMA1855, fasta scores; E(): 1.2e-10, 47.0% identity in 66 aa overlap
YP_002342680.1	NMA1312,  DNA-binding protein, len: 168 aa; unknown, similar to NMA1198, fasta scores; E(): 0, 73.7% identity in 167 aa overlap and NMA1854, fasta scores; E(): 0, 56.3% identity in 167 aa overlap. Contains probable helix-turn-helix motif at aa 21-42 (Score 1051, +2.77 SD)
YP_002342681.1	NMA1313, len: 540 aa; unknown, highly similar to NMA1852, fasta scores; E(): 0, 86.5% identity in 539 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342682.1	NMA1314, len: 522 aa; unknown, similar to SW:YF01_HAEIN (EMBL:U32826), HI1501, Haemophilus influenzae hypothetical protein (520 aa), fasta scores; E(): 0, 40.2% identity in 518 aa overlap and contains a region similar to SW:YF71_HAEIN (EMBL:U32831), HI1571,Haemophilus influenzae hypothetical protein (79 aa), fasta scores; E(): 7.5e-14, 63.2% identity in 76 aa overlap. Highly similar to NMA1851, fasta scores; E(): 0, 49.0% identity in 510 aa overlap
YP_002342683.1	NMA1315, len: 431 aa; unknown, contains regions similar to SW:YF70_HAEIN (EMBL:U32831), HI1570,Haemophilus influenzae hypothetical protein (169 aa),fasta scores; E(): 4.6e-25, 48.7% identity in 154 aa overlap, SW:YF02_HAEIN (EMBL:U32827), HI1502, Haemophilus influenzae hypothetical protein (414 aa), fasta scores; E(): 3.8e-22, 35.4% identity in 237 aa overlap and TR:Q46548 (EMBL:U20249) Bacteroides nodosus plasmid pJIR787 ORF240' (fragment) (240 aa), fasta scores; E(): 4.8e-12, 30.4% identity in 194 aa overlap. Similar to NMA1850, fasta scores; E(): 0, 33.1% identity in 378 aa overlap
YP_002342684.1	NMA1320, len: 381 aa; unknown, shows weak similarity to SW:VPP_BPMU (EMBL:X06796) bacteriophage Mu tail protein (379 aa), fasta scores; E(): 1.2e-12, 24.9% identity in 366 aa overlap. Similar to NMA1830, fasta scores; E(): 0, 44.8% identity in 373 aa overlap
YP_002342685.1	NMA1321, len: 222 aa; unknown, shows weak similarity to SW:VPV_BPP2 (EMBL:AF063097) bacteriophage P2 baseplate assembly protein V (211 aa), fasta scores; E(): 0.85, 24.4% identity in 221 aa overlap and SW:YF18_HAEIN (EMBL:U32827), HI1518, Haemophilus influenzae hypothetical protein (182 aa), fasta scores; E(): 0.0011, 26.8% identity in 194 aa overlap. Similar to NMA1829, fasta scores; E(): 1.8e-32, 46.7% identity in 197 aa overlap
YP_002342686.1	NMA1322, len: 115 aa; unknown, shows weak similarity to SW:YF19_HAEIN (EMBL:U32827), HI1519,Haemophilus influenzae hypothetical protein (135 aa),fasta scores; E(): 0.031, 36.3% identity in 102 aa overlap. Similar to NMA1828, fasta scores; E(): 3.4e-20,51.3% identity in 117 aa overlap
YP_002342687.1	NMA1323, len: 351 aa; unknown, similar to bacterial hypothetical proteins including SW:XKDT_BACSU (EMBL:Z70177), xkdT, phage-like element PbsX protein (348 aa), fasta scores; E(): 1.2e-07, 28.0% identity in 361 aa overlap and SW:YF20_HAEIN (EMBL:U32827), HI1520,Haemophilus influenzae hypothetical protein (355 aa),fasta scores; E(): 4.7e-16, 31.5% identity in 321 aa overlap. Similar at the N-terminus to NMA1827, fasta scores; E(): 1.5e-18, 41.4% identity in 152 aa overlap and at the C-terminus to NMA1826, fasta scores; E(): 1e-29,50.8% identity in 185 aa overlap
YP_002342688.1	NMA1324, len: 186 aa; unknown, shows weak similarity to SW:YMFQ_ECOLI (EMBL:AE000214), ymfQ,Escherichia coli hypothetical protein (194 aa), fasta scores; E(): 0.0001, 28.2% identity in 195 aa overlap. Similar to NMA1825, fasta scores; E(): 9.6e-24, 42.4% identity in 184 aa overlap
YP_002342689.1	NMA1325,  phage tail fibre protein, len: 657 aa; similar in part to SW:VPH_BPHP1 (EMBL:U24159) bacteriophage HP1 probable tail fibre protein (925 aa),fasta scores; E(): 0, 48.7% identity in 452 aa overlap. The N-terminus is similar to that of NMA1824, fasta scores; E(): 3.9e-09, 33.3% identity in 147 aa overlap
YP_002342690.1	NMA1328, len: 201 aa; unknown, C-terminal half is similar to SW:YE02_HAEIN (EMBL:U32820), HI1402,Haemophilus influenzae hypothetical protein (68 aa), fasta scores; E(): 1.3e-08, 56.3% identity in 64 aa overlap. Shows weak similarity to NMA1823, E(): 3.6e-07, 28.8% identity in 191 aa overlap
YP_002342691.1	NMA1329, len: 98 aa; unknown
YP_002342692.1	NMA1332,  periplasmic protein, len: 215 aa; unknown, contains a probable N-terminal signal sequence
YP_002342693.1	NMA1334,  periplasmic protein, len: 123 aa; unknown, contains a probable N-terminal signal sequence
YP_002342694.1	NMA1335,  periplasmic protein, len: 223 aa; unknown, contains a probable N-terminal signal sequence
YP_002342695.1	NMA1336,  oxidoreductase, len: 256 aa; similar to many from both bacterial and eukaryotic sources e.g. weak similarity to SW:TRN1_DATST (EMBL:L20473) Datura stramonium tropinone reductase-I (273 aa), fasta scores; E(): 7.1e-11, 30.2% identity in 205 aa overlap. Similar to SW:YCIK_ECOLI (EMBL:AE000225), yciK, Escherichia coli hypothetical oxidoreductase (252 aa), fasta scores; E(): 6.9e-25, 35.2% identity in 233 aa overlap. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase
YP_002342696.1	NMA1338,  oxidoreductase, len: 437 aa; shows weak similarity to phytoene dehydrogenases e.g. TR:Q40406 (EMBL:X78815), pds, Narcissus pseudonarcissus phytoene dehydrogenase precursor (570 aa), fasta scores; E(): 1.6e-06, 24.7% identity in 473 aa overlap. Also to SW:Y4AB_RHISN (EMBL:AE000064), Y4AB, Rhizobium sp. (strain NGR234) hypothetical protein (417 aa), fasta scores; E(): 8.9e-15, 27.3% identity in 444 aa overlap
YP_002342697.1	NMA1339,  poly-isoprenyl transferase, len: 290 aa; similar to many phytoene synthases e.g. SW:PSY_CAPAN (EMBL:X68017), psy1, Capsicum annuum phytoene synthase precursor (EC 2.5.1.-) (419 aa), fasta scores; E(): 6.7e-26, 36.0% identity in 278 aa overlap (NMA1339 is shorter at the N-terminus) and TR:CAB39693 (EMBL:AL049485), SC6A5.09, Streptomyces coelicolor phytoene synthase (312 aa0, fasta scores; E(): 1.6e-32, 38.0% identity in 287 aa overlap. Similar to NMA1721, fasta scores; E(): 2e-17, 31.0% identity in 226 aa overlap. Contains Pfam match to entry PF00494 SQS_PSY,Squalene and phytoene synthases
YP_002342698.1	involved in the maturation of iron-sulfur cluster-containing proteins
YP_002342699.1	NMA1341, len: 187 aa; unknown
YP_002342700.1	NMA1343, len: 186 aa; unknown
YP_002342701.1	NMA1344, fdx, probable ferredoxin, len: 113 aa; similar to many e.g. SW:FER_ECOLI (EMBL:M88654), fdx,Escherichia coli ferredoxin 2FE-2S (110 aa), fasta scores; E(): 1.2e-30, 67.3% identity in 110 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains
YP_002342702.1	NMA1345, len: 195 aa; unknown
YP_002342703.1	NMA1347, len: 65 aa; unknown, similar to bacterial hypothetical proteins e.g. TR:O69223 (EMBL:AF010139) Azotobacter vinelandii hypothetical protein (68 aa), fasta scores; E(): 2.9e-14, 56.9% identity in 65 aa overlap
YP_002342704.1	NMA1348, len: 133 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YRFH_ECOLI (EMBL:U18997),yrfH, Escherichia coli hypothetical protein (133 aa),fasta scores; E(): 1.3e-19, 45.5% identity in 132 aa overlap. Contains Pfam match to entry PF01479 S4, S4 domain
YP_002342705.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_002342706.1	NMA1350, len: 426 aa; unknown, similar to many bacterial hypothetical proteins e.g. SW:MESJ_ECOLI (EMBL:D49445), mesJ, Escherichia coli  cell cycle protein (432 aa), fasta scores; E(): 0, 34.3% identity in 428 aa overlap
YP_002342707.1	NMA1351,  RNA methyltransferase, len: 261 aa; shows weak similarity to SW:TSNR_STRLU (EMBL:L39157),tsnR, Streptomyces laurentii rRNA (adenosine-2'-O-)-methyltransferase (270 aa), fasta scores; E(): 1.4e-07, 26.1% identity in 253 aa overlap. Similar to many hypothetical proteins e.g. SW:YG73_SYNY3 (EMBL:D90913), SLR1673, Synechocystis sp. (strain PCC 6803) hypothetical tRNA/rRNA methyltransferase (274 aa),fasta scores; E(): 9e-20, 34.1% identity in 267 aa overlap. Shows weak similarity to NMA1127, fasta scores; E(): 1.3e-10, 27.7% identity in 224 aa overlap. Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family
YP_002342708.1	NMA1353,  lipoprotein, len: 78 aa; unknown,contains a  N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site, therefore may be a lipoprotein
YP_002342709.1	NMA1354, len: 137 aa; unknown, lies within a region of unusually low GC content
YP_002342710.1	NMA1355,  periplasmic protein, len: 101 aa; unknown, contains a  N-terminal signal sequence. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342711.1	NMA1356, mpl, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase, len: 458 aa; similar to SW:MPL_ECOLI (EMBL:U14003), mpl, Escherichia coli UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase (EC 6.3.2.-) (457 aa), fasta scores; E(): 0, 57.3% identity in 457 aa overlap. Shows weak similarity to NMA2061, fasta scores; E(): 1.5e-19, 28.4% identity in 479 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family
YP_002342712.1	NMA1358, bioB, probable biotin synthase, len: 350 aa; similar to many e.g. SW:BIOB_ECOLI (EMBL:J04423),bioB, Escherichia coli biotin synthase (EC 2.8.1.6) (346 aa), fasta scores; E(): 0, 59.1% identity in 308 aa overlap
YP_002342713.1	NMA1359, len: 211 aa; unknown
YP_002342714.1	NMA1360, len: 79 aa; unknown
YP_002342715.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_002342716.1	hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide
YP_002342717.1	NMA1363, cysJ, probable sulphite reductase alpha subunit, len: 604 aa; similar to many e.g. SW:CYSJ_ECOLI (EMBL:M23008), cysJ, Escherichia coli sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2) (598 aa), fasta scores; E(): 0, 55.7% identity in 600 aa overlap. Contains Pfam matches to entry PF00667 FAD_binding, FAD binding domain and to entry PF00175 oxidored_fad, Oxidoreductase FAD/NAD-binding domain
YP_002342718.1	NMA1364, cysN, probable sulphate adenylate transferase subunit 1, len: 428 aa; similar to many e.g. SW:CYSN_ECOLI (EMBL:M74586), cysN, Escherichia coli sulfate adenylate transferase subunit 1 (EC 2.7.7.4) (475 aa), fasta scores; E(): 0, 46.8% identity in 432 aa overlap. Contains Pfam match to entry PF00009 GTP_EFTU,Elongation factor Tu family, PS00301 GTP-binding elongation factors signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342719.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_002342720.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
YP_002342721.1	NMA1367, cysG, sirohaem synthase, len: 486 aa; highly similar to TR:P95370 (EMBL:Y10177), cysG, Neisseria meningitidis strain MC58 sirohaem synthase (EC 2.1.1.107) (475 aa), fasta scores; E(): 0, 97.5% identity in 474 aa overlap. Contains Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases,PS00839 Uroporphyrin-III C-methyltransferase signature 1 and PS00840 Uroporphyrin-III C-methyltransferase signature 2
YP_002342722.1	NMA1368,  membrane protein, len: 218 aa; similar to TR:Q46471 (EMBL:U25811) Chromatium vinosum hypothetical protein (231 aa), fasta scores; E(): 1.1e-23,37.9% identity in 211 aa overlap. Contains hydrophobic, membrane-spanning regions. C-terminus contains a poly-Ala tract
YP_002342723.1	NMA1369, len: 296 aa; unknown, similar to the C-terminal half of bacterial hypothetical proteins e.g. SW:YJEF_ECOLI (EMBL:U14003), yjeF, Escherichia coli hypothetical protein (515 aa), fasta scores; E(): 7.8e-28,37.8% identity in 278 aa overlap. Contains Pfam match to entry PF01256 UPF0031, Uncharacterized protein family UPF0031
YP_002342724.1	NMA1370, typA, probable GTP-binding protein, len: 603 aa; similar to many e.g. SW:TYPA_ECOLI (EMBL:L19201),typA, Escherichia coli GTP-binding protein implicated in regulation of virulence factors, fasta scores; E(): 0,64.1% identity in 599 aa overlap. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family,PS00301 GTP-binding elongation factors signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342725.1	NMA1371, vacB, probable ribonuclease, len: 791 aa; similar to many e.g. SW:VACB_SHIFL (EMBL:D11024), vacB,Shigella flexneri chromosomal gene required for expression of virulence genes (also in enteroinvasive Escherichia coli) (760 aa), fasta scores; E(): 0, 44.9% identity in 762 aa overlap. May have a post-transcriptional regulatory role. Also similar to SW:RNB_ECOLI (EMBL:X67913), rnb,Escherichia coli exoribonuclease II (EC 3.1.13.1) (644 aa), fasta scores; E(): 0, 30.0% identity in 580 aa overlap. Contains Pfam matches to entry PF00773 RNB,RNB-like proteins and to entry PF00575 S1, S1 RNA binding domain and PS01175 Ribonuclease II family signature
YP_002342726.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_002342727.1	NMA1373, len: 153 aa; unknown
YP_002342728.1	NMA1374, glnD, probable [protein-PII] uridylyltransferase, len: 852 aa; similar to many e.g. SW:GLND_ECOLI (EMBL:M96431), glnD, Escherichia coli [protein-PII] uridylyltransferase (EC 2.7.7.59) (890 aa),fasta scores; E(): 0, 33.1% identity in 865 aa overlap
YP_002342729.1	NMA1375,  transcriptional regulator, len: 106 aa; similar to e.g. regulatory proteins of restriction modification systems e.g. TR:Q52622 (EMBL:M77223), pvuIIC,Proteus vulgaris regulatory transcription factor C (84 aa), fasta scores; E(): 1.8e-05, 42.2% identity in 64 aa overlap. Similar to TR:AAD39136 (EMBL:AF123569), nmeSIC,Neisseria meningitidis strain 800615 (serotype B:4:P1.4)  control element (70 aa), fasta scores; E(): 4.3e-05, 46.0% identity in 50 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. Contains a probable helix-turn-helix motif at aa 36-57 (Score 1818,+5.38 SD)
YP_002342730.1	NMA1376, bfrB, probable bacterioferritin B, len: 157 aa; similar to many e.g. SW:BFRB_NEIGO (EMBL:U76634),bfrB, Neisseria gonorrhoeae bacterioferritin B (157 aa),fasta scores; E(): 0, 99.4% identity in 157 aa overlap and SW:BFR_AZOVI (EMBL:M83692), bfr, Azotobacter vinelandii bacterioferritin (156 aa), fasta scores; E(): 0, 62.2% identity in 156 aa overlap. Similar to NMA1377, fasta scores; E(): 3.1e-17, 39.9% identity in 153 aa overlap
YP_002342731.1	NMA1377, bfrA, probable bacterioferritin A, len: 154 aa; similar to many e.g. SW:BFRA_NEIGO (EMBL:U76633),bfrA, Neisseria gonorrhoeae bacterioferritin A (154 aa),fasta scores; E(): 0, 99.4% identity in 154 aa overlap and SW:BFR_PSEPU (EMBL:U66717), bfr, Pseudomonas putida bacterioferritin (154 aa), fasta scores; E(): 0, 61.0% identity in 154 aa overlap. Similar to NMA1376, fasta scores; E(): 2.2e-17, 39.9% identity in 153 aa overlap
YP_002342732.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_002342733.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
YP_002342734.1	NMA1380, len: 91 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YBED_ECOLI (EMBL:L07636),ybeD, Escherichia coli hypothetical protein (87 aa),fasta scores; E(): 3.1e-08, 37.8% identity in 82 aa overlap
YP_002342735.1	NMA1381, probable integral membrane protein, len: 356 aa; similar to many bacterial hypothetical proteins e.g. SW:PERM_ECOLI (EMBL:AE000335), perm, Escherichia coli permease (353 aa), fasta scores; E(): 1.5e-19,26.2% identity in 313 aa overlap. Contains Pfam match to entry PF01594 DUF20,  permease. Contains hydrophobic, probable membrane-spanning regions
YP_002342736.1	NMA1382,  periplasmic protein, len: 315 aa; similar to many hypothetical proteins found in both bacteria and eukaryotes e.g. TR:O60376 (EMBL:AC004472),P1.11659_4, Homo sapiens hypothetical protein (357 aa),fasta scores; E(): 0, 48.4% identity in 289 aa overlap and TR:Q9ZDK0 (EMBL:AJ235271), RP328, Rickettsia prowazekii hypothetical protein (311 aa), fasta scores; E(): 0, 48.6% identity in 315 aa overlap. Contains Pfam match to entry PF01145 Band_7, Band 7 family. Contains a probable N-terminal signal sequence
YP_002342737.1	NMA1383,  membrane protein, len: 135 aa; unknown, contains hydrophobic,  membrane-spanning regions
YP_002342738.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_002342740.1	NMA1391,  periplasmic protein, len: 171 aa; unknown, contains a probable N-terminal signal sequence
YP_002342741.1	NMA1394, len: 131 aa; unknown
YP_002342742.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_002342743.1	NMA1396,  membrane protein, len: 144 aa; unknown, contains a hydrophobic,  membrane-spanning region
YP_002342744.1	NMA1397, hupB, probable DNA-binding protein, len: 89 aa; similar to many e.g. SW:DBHB_ECOLI (EMBL:X53241),hupB, Escherichia coli DNA-binding protein HU-beta (90 aa), fasta scores; E(): 1.4e-19, 68.5% identity in 89 aa overlap. Similar to NMA1868, fasta scores; E(): 3.6e-21,69.7% identity in 89 aa overlap. Contains Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein and PS00045 Bacterial histone-like DNA-binding proteins signature
YP_002342745.1	NMA1398, lon, probable ATP-dependent protease, len: 820 aa; similar to many e.g. SW:LON_ECOLI (EMBL:L12349),lon, Escherichia coli ATP-dependent protease (EC 3.4.21.53) (784 aa), fasta scores; E(): 0, 65.5% identity in 796 aa overlap. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA), PS01046 ATP-dependent serine proteases, lon family,serine active site and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342746.1	NMA1400, len: 331 aa; unknown, shows weak similarity to parts bacterial hypothetical proteins e.g. TR:CAB49354 (EMBL:AJ248284) Pyrococcus abyssi hypothetical protein (197 aa), fasta scores; E(): 1.5e-06, 33.5% identity in 179 aa overlap. Contains PS00092 N-6 Adenine-specific DNA methylases signature
YP_002342747.1	NMA1401, recD, exodeoxyribonuclease V alpha subunit, len: 581 aa; highly similar to TR:O68924 (EMBL:AF058330), recD, Neisseria gonorrhoeae exodeoxyribonuclease V alpha subunit (581 aa), fasta scores; E(): 0, 95.2% identity in 580 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342748.1	NMA1402, probable ABC-transporter ATP-binding protein, len: 231 aa; similar to many e.g. SW:GLNQ_BACST (EMBL:M61017), glnQ, Bacillus stearothermophilus glutamine transport ATP-binding protein (242 aa), blastp scores; Expect 3.6e-29 and SW:YCFV_ECOLI (EMBL:AE000212), ycfV,Escherichia coli hypothetical ABC transporter ATP-binding protein (233 aa), fasta scores; E(): 0, 53.8% identity in 223 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342749.1	NMA1403,  integral membrane protein, len: 415 aa; unknown, similar to many bacterial hypothetical proteins e.g. SW:YCFW_ECOLI (EMBL:AE000212), yxfW,Escherichia coli hypothetical protein (414 aa), fasta scores; E(): 0, 35.3% identity in 405 aa overlap. Contains hydrophobic, membrane-spanning regions
YP_002342750.1	NMA1405,  periplasmic protein, len: 92 aa; unknown, contains a  N-terminal signal sequence
YP_002342751.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_002342752.1	NMA1407,  peptidyl-prolyl cis-trans isomerase, len: 512 aa; similar to e.g. SW:CYPD_ECOLI (EMBL:AE000150), ppiD, Escherichia coli peptidyl-prolyl cis-trans isomerase D (EC 5.2.1.8) (623 aa), fasta scores; E(): 8.4e-14, 21.7% identity in 608 aa overlap. Contains a probable N-terminal signal sequence
YP_002342753.1	NMA1408, len: 124 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:YFFB_ECOLI (EMBL:X57403),yffB, Escherichia coli hypothetical protein (118 aa),fasta scores; E(): 5.8e-15, 38.5% identity in 117 aa overlap
YP_002342754.1	NMA1409, probable ABC-transporter ATP-binding protein, len: 542 aa; similar to many e.g. SW:TLRC_STRFR (EMBL:M57437), tlrC, Streptomyces fradiae tylosin resistance ATP-binding protein (548 aa), blastp scores; Expect 1.4e-45 and SW:YBIT_ECOLI (EMBL:AE000184), ybiT,Escherichia coli hypothetical ABC-transporter ATP-binding protein (530 aa), fasta scores; E(): 0, 65.6% identity in 543 aa overlap. Contains two Pfam matches to entry PF00005 ABC_tran, ABC transporter and two PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342755.1	catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
YP_002342756.1	NMA1411, len: 102 aa; unknown
YP_002342757.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_002342758.1	NMA1413, rpe, probable ribulose-phosphate 3-epimerase, len: 242 aa; similar to many e.g. SW:RPE_ECOLI (EMBL:Z19601), rpe, Escherichia coli ribulose-phosphate 3-epimerase (EC 5.1.3.1) (225 aa),fasta scores; E(): 0, 66.2% identity in 225 aa overlap. Contains Pfam match to entry PF00834 Ribul_P_3_epim,Ribulose-phosphate 3 epimerase family, PS01085 Ribulose-phosphate 3-epimerase family signature 1 and PS01086 Ribulose-phosphate 3-epimerase family signature 2
YP_002342759.1	NMA1414,  periplasmic protein, len: 144 aa; shows weak similarity to SW:SPY_ECOLI (EMBL:Y07714), spy,Escherichia coli spheroplast protein (161 aa), fasta scores; E(): 0.0013, 27.6% identity in 134 aa overlap. Contains a  N-terminal signal sequence
YP_002342760.1	NMA1415, len: 287 aa; unknown, similar to the C-terminal half of TR:Q55502 (EMBL:D64006) Synechocystis sp. (strain PCC 6803) hypothetical protein (436 aa), fasta scores; E(): 0, 46.9% identity in 241 aa overlap and also to TR:O66668 (EMBL:AE000684), AQ_336, Aquifex aeolicus hypothetical protein (196 aa), fasta scores; E(): 3.4e-19,46.5% identity in 142 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342761.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_002342762.1	NMA1417,  molybdopterin-guanine dinucleotide biosynthesis protein A, len: 192 aa; similar to bacterial mobA genes e.g. SW:MOBA_ECOLI (EMBL:L19201),mobA, Escherichia coli molybdopterin-guanine dinucleotide biosynthesis protein A (194 aa), fasta scores; E(): 1.9e-14, 31.4% identity in 185 aa overlap
YP_002342763.1	NMA1418, probable two-component system sensor kinase, len: 590 aa; similar to many e.g. SW:NARX_ECOLI (EMBL:X13360), narX, Escherichia coli nitrate/nitrite sensor protein (EC 2.7.3.-) (598 aa), fasta scores; E(): 3.2e-17, 25.9% identity in 609 aa overlap. Contains Pfam match to entry PF00672 DUF5, Domain found in bacterial signal proteins. Contains two hydrophobic, membrane-spanning regions
YP_002342764.1	NMA1419, probable two-component system response regulator, len: 218 aa; similar to many e.g. TR:CAB44989 (EMBL:AJ131854), narL, Pseudomonas stutzeri nitrate and nitrite response regulator (218 aa), fasta scores; E(): 8.5e-31, 43.3% identity in 210 aa overlap. Contains probable helix-turn-helix motif at aa 169-190 (Score 1324,+3.70 SD). Contains Pfam matches to entry PF00072 response_reg, Response regulator receiver domain and to entry PF00196 GerE, Bacterial regulatory proteins, luxR family and PS00622 Bacterial regulatory proteins, luxR family signature
YP_002342765.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_002342766.1	NMA1424, len: 224 aa; unknown
YP_002342767.1	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
YP_002342768.1	bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis
YP_002342769.1	NMA1433, len: 436 aa; unknown, similar to many hypothetical proteins e.g. SW:YCAJ_HAEIN (EMBL:U32833),HI1590, Haemophilus influenzae hypothetical protein (446 aa), fasta scores; E(): 0, 54.0% identity in 437 aa overlap. may have some role in DNA replication or repair as the N-terminal half is similar to yeast replication factors e.g. SW:RFC3_YEAST (EMBL:L18755), rfc3,Saccharomyces cerevisiae replication factor C 40 kD subunit (340 aa), fasta scores; E(): 1.4e-10, 30.5% identity in 233 aa overlap and to bacterial helicase components SW:RUVB_THEMA (EMBL:U38840), ruvB, Thermotoga maritima (334 aa), fasta scores; E(): 1.1e-07, 28.3% identity in 244 aa overlap. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA) and PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342770.1	NMA1435, len: 161 aa; unknown, lies within a region of unusually low GC content
YP_002342771.1	NMA1436, len: 259 aa; unknown, rich in Ser, Thr and Asn, lies within a region of unusually low GC content
YP_002342772.1	NMA1437, probable lysR-family transcriptional regulator, len: 304 aa; shows weak similarity to many e.g. SW:XAPR_ECOLI (EMBL:X63976), xapR, Escherichia coli xanthosine operon regulatory protein (294 aa), fasta scores; E(): 1.6e-11, 23.7% identity in 295 aa overlap and TR:O30441 (EMBL:AF006000), brg1, Bordetella pertussis transcriptional regulator homologue regulated by the oxygen-responsive transcriptional regulator btr (291 aa),fasta scores; E(): 5.4e-13, 28.7% identity in 296 aa overlap. Contains probable helix-turn-helix motif at aa 17-38 (Score 1810, +5.35 SD). Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family and PS00044 Bacterial regulatory proteins, lysR family signature
YP_002342773.1	NMA1438,  integral membrane protein, len: 489 aa; unknown, contains hydrophobic,  membrane-spanning regions
YP_002342774.1	NMA1439,  lipoprotein, len: 123 aa; unknown, contains a probable N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342775.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_002342776.1	NMA1441, len: 264 aa; unknown
YP_002342777.1	NMA1442, fpr, probable ferredoxin--NADP reductase,len: 258 aa; similar to many e.g. SW:FENR_AZOVI (EMBL:L36319), fpr, Azotobacter vinelandii ferredoxin--NADP reductase (EC 1.18.1.2) (257 aa), fasta scores; E(): 0, 69.8% identity in 255 aa overlap. Similar to NMA1664, fasta scores; E(): 1.3e-30, 34.6% identity in 257 aa overlap. Contains Pfam match to entry PF00175 oxidored_fad, Oxidoreductase FAD/NAD-binding domain
YP_002342778.1	NMA1444, probable P-type cation-transporting ATPase, len: 823 aa; similar to many e.g. SW:COPA_ENTHR (EMBL:L13292), copA, Enterococcus hirae copper/potassium-transporting ATPase A (EC 3.6.1.36) (727 aa), fasta scores; E(): 0, 34.0% identity in 744 aa overlap. Similar to NMA1539, fasta scores; E(): 0, 34.4% identity in 735 aa overlap. Contains hydrophobic, probable membrane-spanning regions. Contains two Pfam matches to entry PF00122 E1-E2_ATPase, E1-E2 ATPases and PS00154 E1-E2 ATPases phosphorylation site
YP_002342779.1	NMA1445, len: 369 aa; unknown, similar to many hypothetical proteins contains  ATP/GTP-binding domains e.g. SW:HFLX_ECOLI (EMBL:U00005), hflX,Escherichia coli GTP-binding protein (426 aa), fasta scores; E(): 0, 48.5% identity in 375 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002342780.1	NMA1446,  periplasmic protein, len: 426 aa; contains  N-terminal signal sequence
YP_002342781.1	NMA1447, len: 241 aa; unknown, similar to bacterial hypothetical proteins e.g. SW:Y882_HAEIN (EMBL:U32770),HI0882, Haemophilus influenzae hypothetical protein (245 aa), fasta scores; E(): 0, 76.9% identity in 212 aa overlap
YP_002342782.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_002342783.1	NMA1449, gshA, probable glutamate--cysteine ligase,len: 449 aa; similar to TR:Q56277 (EMBL:U81808), gshA,Thiobacillus ferrooxidans glutamate--cysteine ligase (EC 6.3.2.2) (436 aa), fasta scores; E(): 0, 45.7% identity in 446 aa overlap
YP_002342784.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_002342785.1	NMA1451,  lipoprotein, len: 84 aa; unknown,contains N-terminal signal sequence and an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342786.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_002342787.1	NMA1453, DNA modification methylase, len: 423 aa; almost identical to SW:MTN4_NEILA (EMBL:U06074) Neisseria lactamica modification methylase NlaIV (EC ) (423 aa), fasta scores; E(): 0, 99.1% identity in 423 aa overlap and TR:Q59605 (EMBL:U43735), dcmE, Neisseria gonorrhoeae modification methylase (EC ) (423 aa),fasta scores; E(): 0, 97.9% identity in 423 aa overlap. Also similar to others from Neisseria meningitidis e.g. NMA1035, fasta scores; E(): 4.5e-21, 29.2% identity in 432 aa overlap. Contains Pfam match to entry PF00145 DNA_methylase, C-5 cytosine-specific DNA methylase and PS00094 C-5 cytosine-specific DNA methylases active site. Lies within a region of unusually low GC content
YP_002342788.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_002342789.1	NMA1457,  periplasmic protein, len: 187 aa; unknown, contains a  N-terminal signal sequence
YP_002342790.1	catalyzes the formation of fumarate from aspartate
YP_002342791.1	NMA1460, probable integral membrane protein, len: 291 aa; similar to SW:YD76_HAEIN (EMBL:U32818), HI1376,Haemophilus influenzae hypothetical protein (291 aa),fasta scores; E(): 0, 54.8% identity in 292 aa overlap. Contains hydrophobic,  membrane-spanning regions
YP_002342792.1	NMA1461, probable dnaJ-family protein, len: 240 aa; unknown, N-terminal approx. 70 aa contains a J-domain,suggesting involvement with hsp70, while the remainder of the protein contains two hydrophobic, membrane-spanning regions. Only the N-terminus shows significant similarity to other proteins e.g. SW:DNAJ_LEGPN (EMBL:U15010), dnaJ, Legionella pneumophila DnaJ protein (379 aa), fasta scores; E(): 1.6e-09,65.6% identity in 64 aa overlap. Contains Pfam match to entry PF00226 DnaJ, DnaJ domain and PS00636 Nt-dnaJ domain signature
YP_002342793.1	NMA1462, len: 159 aa; unknown, shows weak similarity to SW:EBSC_ENTFA (EMBL:L23802) Enterococcus faecalis  regulatory protein (164 aa), fasta scores; E(): 3.6e-08, 23.8% identity in 143 aa overlap and to other bacterial hypothetical proteins e.g. SW:YBAK_ECOLI (EMBL:AE000154), ybaK, Escherichia coli hypothetical protein (159 aa), fasta scores; E(): 1.2e-12,35.7% identity in 157 aa overlap
YP_002342794.1	NMA1463, len: 120 aa; unknown, similar to hypothetical proteins e.g. SW:Y117_HAEDU (EMBL:AF017750) Haemophilus ducreyi hypothetical protein (117 aa), fasta scores; E(): 1e-17, 46.8% identity in 111 aa overlap. Contains Pfam match to entry PF01042 DUF10, Domain of unknown function
YP_002342795.1	NMA1464, len: 288 aa; unknown, shows very weak similarity to some bacterial hypothetical proteins e.g. SW:UP14_ECOLI (EMBL:U28375), ygfZ, Escherichia coli hypothetical protein (325 aa), fasta scores; E(): 1.2e-07,25.0% identity in 284 aa overlap
YP_002342796.1	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs
YP_002342797.1	NMA1466, probable type III restriction-modification system endonuclease, len: 979 aa; similar to many e.g. SW:T3RE_BPP1 (EMBL:X06287), res, bacteriophage P1 type III restriction-modification system EcoPI enzyme (EC 3.1.21.5) (970 aa), fasta scores; E(): 0, 55.8% identity in 980 aa overlap
YP_002342798.1	NMA1469, ppiA, probable peptidyl-prolyl cis-trans isomerase A, len: 185 aa; similar to many e.g. SW:CYPH_ECOLI (EMBL:M55429), ppiB, Escherichia coli probable peptidyl-prolyl cis-trans isomerase A precursor (EC 5.2.1.8) (190 aa), fasta scores; E(): 9.4e-32, 54.9% identity in 182 aa overlap. Also similar to NMA1002, fasta scores; E(): 7.9e-21, 45.7% identity in 162 aa overlap. Contains Pfam match to entry PF00160 pro_isomerase,Peptidyl-prolyl cis-trans isomerase and PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature
YP_002342799.1	NMA1470, len: 308 aa; unknown, similar to SW:YEIR_ECOLI (EMBL:AE000307), yeiR, Escherichia coli hypothetical protein (328 aa), fasta scores; E(): 1.1e-27,33.3% identity in 318 aa overlap. Also shows similarity at the N-terminus to SW:COBW_PSEDE (EMBL M62866), cobW,Pseudomonas denitrificans gene involved in cobalamin biosynthesis (353 aa), fasta scores; E(): 6.4e-11, 28.8% identity in 215 aa overlap
YP_002342800.1	NMA1471,  cation uptake regulator, len: 158 aa; shows weak similarity to many cation uptake regulator proteins e.g. SW:ZUR_ECOLI (EMBL:U00006), zur, Escherichia coli zinc uptake regulation protein (171 aa), fasta scores; E(): 4.1e-07 30.6% identity in 160 aa overlap and SW:FUR_STAEP (EMBL:X97011), fur, Staphylococcus epidermidis ferric uptake regulation protein (138 aa),fasta scores; E(): 0.22, 22.8% identity in 158 aa overlap. Also similar to a protein identified as a virulence candidate in Pseudomonas aeruginosa TR:P72159 (EMBL:U58365), np20, fasta scores; E(): 1e-07, 37.3% identity in 75 aa overlap
YP_002342801.1	NMA1472, probable low molecular weight protein-tyrosine-phosphatase, len: 151 aa; similar to many protein-tyrosine-phosphatases e.g. SW:PTPA_STRCO (EMBL:U37580), ptpA, Streptomyces coelicolor A3(2) low molecular weight protein-tyrosine-phosphatase (EC 3.1.3.48) (164 aa), fasta scores; E(): 3e-16, 39.2% identity in 153 aa overlap and SW:PPAL_SCHPO (EMBL:L33929), stp1, Schizosaccharomyces pombe low molecular weight phosphotyrosine protein phosphatase (EC 3.1.3.48) (156 aa), fasta scores; E(): 2.7e-13, 40.2% identity in 132 aa overlap. Contains Pfam match to entry PF01451 LMWPc, Low molecular weight phosphotyrosine protein phosphatase
YP_002342802.1	NMA1473, len: 371 aa; unknown, similar to many bacterial hypothetical proteins e.g. SW:YXAA_BACSU (EMBL:AB005554), yxaA, Bacillus subtilis hypothetical protein (382 aa), fasta scores; E(): 0, 40.2% identity in 378 aa overlap. Lies within a region of unusually low GC content
YP_002342803.1	NMA1474, len: 365 aa; unknown
YP_002342804.1	NMA1475, len: 543 aa; unknown, shares N-terminal similarity with some bacterial hypothetical proteins e.g. TR:O05979 (EMBL:Y11779) Rickettsia prowazekii hypothetical protein (216 aa), fasta scores; E(): 3e-29, 43.8% identity in 185 aa overlap
YP_002342805.1	NMA1476,  mercuric ion binding protein,len: 94 aa; similar to many small mercuric ion binding proteins e.g. SW:MERP_ACICA (EMBL:L04303), merP,Acinetobacter calcoaceticus plasmid pKLH2 mercuric transport protein periplasmic component precursor (91 aa),fasta scores; E(): 3e-06, 37.7% identity in 69 aa overlap and SW:MERP_PSEFL (EMBL:X73112), merP, Pseudomonas fluorescens plasmid pMER327 mercuric transport protein periplasmic component precursor (91 aa), fasta scores; E(): 4.9e-06, 36.2% identity in 69 aa overlap. Contains Pfam match to entry PF00403 HMA, Heavy-metal-associated domain
YP_002342806.1	NMA1478,  polysaccharide modification protein, len: 478 aa; similar to TR:Q51392 (EMBL:U50202),algI, Pseudomonas aeruginosa protein involved in alginate O-acetylation (520 aa), fasta scores; E(): 4.9e-33, 32.9% identity in 444 aa overlap and TR:O70067 (EMBL:AF049357),glg2, Streptococcus mutans CDS involved in intracellular polysaccharide accumulation (420 aa), fasta scores; E(): 1.5e-21, 28.7% identity in 407 aa overlap. Also shows weaker similarity to SW:DLTB_BACSU (EMBL:X73124), dltB,Bacillus subtilis protein involved in biosynthesis of D-alanyl-lipoteichoic acid (395 aa), fasta scores; E(): 3.1e-17, 25.3% identity in 395 aa overlap. Contains hydrophobic,  membrane-spanning regions
YP_002342807.1	NMA1479,  periplasmic protein, len: 327 aa; unknown, contains a probable N-terminal signal sequence
YP_002342808.1	NMA1480,  periplasmic protein, len: 397 aa; unknown, contains a  N-terminal signal sequence
YP_002342809.1	NMA1481, probable transposase for IS1655, len: 321 aa; similar to many e.g. SW:TRA4_BACFR (EMBL:M17808) Bacteroides fragilis transposase for insertion sequence element (326 aa), fasta scores; E(): 0, 42.3% identity in 310 aa overlap. Contains Pfam match to entry PF01460 Transposase_4, Transposase IS30 family. Contains probable helix-turn-helix motif at aa 22-43 (Score 1705, +4.99 SD)
YP_002342810.1	activates fatty acids by binding to coenzyme A
YP_002342811.1	NMA1483, probable transmembrane transport protein,len: 660 aa; similar to many e.g. SW:OPUD_BACSU (EMBL:U50082), opuD, Bacillus subtilis glycine betaine transporter (512 aa), fasta scores; E(): 0, 42.8% identity in 493 aa overlap and SW:BETT_ECOLI (EMBL:X52905), betT,Escherichia coli high-affinity choline transport protein (677 aa), fasta scores; E(): 0, 34.2% identity in 663 aa overlap. Possibly involved in osmotic regulation. Highly similar to SW:YH06_HAEIN (EMBL:U32843), HI1706,Haemophilus influenzae probable transport protein (669 aa), fasta scores; E(): 0, 75.8% identity in 669 aa overlap. Contains hydrophobic, probable membrane-spanning regions. Contains PS01303 BCCT family of transporters signature
YP_002342812.1	NMA1485, gcr, site-specific recombinase, len: 668 aa; highly similar to TR:O05319 (EMBL:U82253) Neisseria gonorrhoeae site-specific recombinase (439 aa), fasta scores; E(): 0, 96.6% identity in 439 aa overlap. GC frameplot and codon usage plots predict a start codon 678 bp upstream of the functionally characterised start codon described in EMBL:U82253. The sequence described in EMBL:U82253 does not extend upstream of codon 188 in our predicted CDS
YP_002342813.1	NMA1486, probable transposase for IS1655, len: 321 aa; similar to many e.g. SW:TRA4_BACFR (EMBL:M17808) Bacteroides fragilis transposase for insertion sequence element (326 aa), fasta scores; E(): 0, 42.3% identity in 310 aa overlap. Contains Pfam match to entry PF01460 Transposase_4, Transposase IS30 family. Contains probable helix-turn-helix motif at aa 22-43 (Score 1705, +4.99 SD)
YP_002342814.1	NMA1487,  transposase for IS1016, len: 197 aa; similar to many e.g. TR:Q48234 (EMBL:X59756) ORF from Haemophilus influenzae insertion sequence IS1016-V6 (191 aa), fasta scores; E(): 0, 70.3% identity in 175 aa overlap.
YP_002342815.1	NMA1488, mltB, murein hydrolase, len: 321aa; similar to several eg. SW:P41052 (MLTB_ECOLI) membrane-bound lytic murein transglycosylase from Escherichia coli (361 aa) fasta scores; E(): 0, 38.4% identity in 310 aa overlap. Contains  N-terminal signal sequence.
YP_002342816.1	NMA1490,  oxidoreductase, len: 517aa; weakly similar to many acyl-dehydrogenases eg. SW:P52042 (ACDS_CLOAB) (379 aa) fasta scores; E(): 0.00073, 20.8% identity in 380 aa overlap.
YP_002342817.1	NMA1491, mfd, transcription-repair coupling factor,len: 1296aa; similar to many eg. SW:P30958 (MFD_ECOLI) (1148 aa) fasta scores; E(): 0, 44.2% identity in 1305 aa overlap. Contains Pfam match to entry PF00270 DEAD,DEAD/DEAH box helicase and to entry PF00271 helicase_C,Helicases conserved C-terminal domain
YP_002342818.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_002342819.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_002342820.1	NMA1494, unknown, len: 146aa; N-terminal region similar to TR:O66525 (EMBL:AE000675) hypothetical protein (132 aa) fasta scores; E(): 0.005, 29.6% identity in 115 aa overlap.
YP_002342821.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_002342822.1	NMA1496, unknown, len: 92aa; similar to SW:Q46894 (YGBQ_ECOLI) hypothetical protein from Escherichia coli (103 aa) fasta scores; E(): 1.1e-10, 46.6% identity in 88 aa overlap.
YP_002342823.1	NMA1497,  iron-sulphur binding protein,len: 96aa; similar to SW:P37910 (YFAE_ECOLI) hypothetical protein from Escherichia coli (84 aa) fasta scores; E(): 4.2e-11, 45.8% identity in 83 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains and Prosite match to PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature.
YP_002342824.1	B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA
YP_002342825.1	NMA1499,  type-II restriction endonuclease,len: 395aa; similar to SW:P14633 (T2E2_ECOLI) restriction endonuclease EcoRII from Escherichia coli (404 aa) fasta scores; E(): 2.9e-29, 34.4% identity in 392 aa overlap.
YP_002342826.1	NMA1500, probable modification methylase, len: 337aa; similar to many eg. SW:P05101 (MTS2_SHISO) modification methylase from Shigella sonnei (379 aa) fasta scores; E(): 0, 53.1% identity in 324 aa overlap. Contains Pfam match to entry PF00145 DNA_methylase, C-5 cytosine-specific DNA methylase and Prosite match to PS00095 C-5 cytosine-specific DNA methylases C-terminal signature and PS00094 C-5 cytosine-specific DNA methylases active site.
YP_002342827.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002342828.1	NMA1503, unknown, len: 103aa
YP_002342829.1	NMA1504, plsC, 1-acyl-SN-glycerol-3-phosphate acyltransferase, len: 255aa; similar to eg. TR:Q59618 (EMBL:U21807) plsC, 1-acyl-SN-glycerol-3-phosphate acyltransferase from Neisseria meningitidis serogroup B (257 aa) fasta scores; E(): 0, 97.3% identity in 257 aa overlap. Contains Pfam match to entry PF01553 Acyltransferase. Contains  membrane spanning hydrophobic regions.
YP_002342830.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_002342831.1	NMA1506, unknown, len: 221aa
YP_002342832.1	NMA1507,  membrane-bound lytic murein transglycosylase, len: 658aa; similar to SW:P23931 (MLTD_ECOLI) membrane-bound lytic murein transglycosylase D precursor from Escherichia coli (452 aa) fasta scores; E(): 5.8e-31, 33.3% identity in 399 aa overlap. Contains three Pfam matches to entry PF01476 PG_binding_2, peptidoglycan binding domain and Pfam match to entry PF01464 SLT, Transglycosylase SLT domain.
YP_002342833.1	NMA1508,  ribosomal small subunit pseudouridine synthase, len: 230aa; similar to many eg. SW:P33918 (RSUA_ECOLI) RsuA, ribosomal small subunit pseudouridine synthase A from Escherichia coli (231 aa) fasta scores; E(): 1.4e-21, 36.4% identity in 225 aa overlap. Contains Prosite match to PS01149 RsuA family of pseudouridine synthase signature.
YP_002342834.1	NMA1514, cmk, cytidylate kinase, len: 218aa; similar to many eg. SW:P23863 (KCY_ECOLI) cmk, cytidylate kinase from Escherichia coli (227 aa) fasta scores; E(): 1.6e-30, 46.3% identity in 216 aa overlap
YP_002342835.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_002342836.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_002342837.1	NMA1517, probable transcriptional regulator, len: 135aa; N-terminal region similar to many eg. SW:P22853 (MERR_BACSR) mercuric resistance operon regulator from Bacillus sp. (strain RC607) (132 aa) fasta scores; E(): 0.00031, 25.5% identity in 110 aa overlap. Also similar to SW:P44558 (Y186_HAEIN) hypothetical transcriptional regulator from Haemophilus influenzae (135 aa) fasta scores; E(): 0, 93.3% identity in 135 aa overlap. Contains Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family and Prosite match to PS00552 Bacterial regulatory proteins, merR family signature. Also contains probable coiled-coil in the C-terminal region and helix-turn-helix 4-25aa (+3.80 SD).
YP_002342838.1	NMA1518, adhC, alcohol dehydrogenase class-III,glutathione-dependent formaldehyde dehydrogenase, len: 378aa; similar to many eg. SW:P25437 (ADH3_ECOLI) adhC,alcohol dehydrogenase class-III from Escherichia coli (369 aa) fasta scores; E(): 0, 90.0% identity in 369 aa overlap. Contains Pfam match to entry PF00107 adh_zinc,Zinc-binding dehydrogenases and Prosite match to PS00059 Zinc-containing alcohol dehydrogenases signature.
YP_002342839.1	NMA1519, esd, esterase D, len: 275aa; similar to SW:P10768 (ESTD_HUMAN) esd, esterase D from Homo sapiens (Human) (282 aa) fasta scores; E(): 0, 52.9% identity in 278 aa overlap. Also similar to SW:P44556 (YAIM_HAEIN) hypothetical protein from Haemophilus influenzae (275 aa) fasta scores; E(): 0, 95.3% identity in 275 aa overlap. Contains Pfam match to entry PF00756 Esterase,  esterase.
YP_002342840.1	NMA1520,  nucleotide-binding protein, len: 383aa; similar to many of undefined function eg. SW:P46442 (YHCM_ECOLI) hypothetical protein from Escherichia coli (375 aa) fasta scores; E(): 0, 38.1% identity in 370 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002342841.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_002342842.1	NMA1522, conserved hypothetical protein, len: 364aa; similar to many eg. SW:Q51385 (YFGB_PSEAE) hypothetical protein from Pseudomonas aeruginosa (379 aa) fasta scores; E(): 0, 57.9% identity in 356 aa overlap.
YP_002342843.1	NMA1523,  lipoprotein, len: 253aa; similar to TR:O67735 (EMBL:AE000762) hypothetical protein from Aquifex aeolicus (342 aa) fasta scores; E(): 3e-07, 29.7% identity in 195 aa overlap. Contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site and  uncleavable N-terminal signal sequence.
YP_002342844.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_002342845.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002342846.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_002342847.1	NMA1527, ftsK-like cell division/stress response protein, len: 767aa; similar to many eg. TR:Q9Z3U1 (EMBL:AF095845) cell division/stress response protein from Pseudomonas syringae (801 aa) fasta scores; E(): 0, 44.7% identity in 774 aa overlap. Contains Pfam match to entry PF01580 FtsK_SpoIIIE and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002342848.1	NMA1528, uraA, uracil permease, len: 403aa; similar to many eg. SW:P41006 (PYRP_BACCL) uracil permease from Bacillus caldolyticus (432 aa) fasta scores; E(): 0, 45.3% identity in 395 aa overlap. Contains Pfam match to entry PF00860 xan_ur_permease, Xanthine/uracil permeases family and Prosite match to PS01116 Xanthine/uracil permeases family signature. Also contains  membrane spanning hydrophobic regions.
YP_002342849.1	NMA1529, unknown, len: 160aa
YP_002342850.1	NMA1532, pss, phosphatidylserine synthase, len: 248aa; similar to many eg. SW:Q48269 (PSS_HELPY) pss,phosphatidylserine synthase from Helicobacter pylori (237 aa) fasta scores; E(): 5.9e-21, 35.7% identity in 221 aa overlap. Contains Prosite match to PS00379 CDP-alcohol phosphatidyltransferases signature. Also contains membrane spanning hydrophobic regions.
YP_002342851.1	NMA1533, conserved hypothetical integral membrane protein, len: 268aa; similar to many eg. SW:P44070 (Y902_HAEIN) hypothetical protein from Haemophilus influenzae (264 aa) fasta scores; E(): 5.1e-23, 33.7% identity in 261 aa overlap. Contains  membrane spanning hydrophobic regions.
YP_002342852.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_002342853.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_002342854.1	NMA1536, priB, primosomal replication protein, len: 100aa; similar to many eg. SW:P07013 (PRIB_ECOLI) priB,primosomal replication protein N from Escherichia coli (103 aa) fasta scores; E(): 0.016, 31.2% identity in 77 aa overlap.
YP_002342855.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_002342856.1	NMA1538, trxB, thioredoxin reductase, len: 316aa; similar to many eg. SW:P09625 (TRXB_ECOLI) trxB,thioredoxin reductase from Escherichia coli (320 aa) fasta scores; E(): 0, 66.7% identity in 312 aa overlap. Contains Prosite match to PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
YP_002342857.1	NMA1539, probable cation-transporting ATPase, len: 725aa; similar to many eg. SW:P32113 (COPA_ENTHR) copper/potassium-transporting ATPase A from Enterococcus hirae (834 aa) fasta scores; E(): 0, 40.7% identity in 732 aa overlap. Contains Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPases, Pfam match to entry PF00403 HMA, Heavy-metal-associated domain, Prosite match to PS01047 Heavy-metal-associated domain and Prosite match to PS00154 E1-E2 ATPases phosphorylation site. Also contains membrane spanning hydrophobic regions.
YP_002342858.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_002342859.1	NMA1541, unknown, len: 477aa
YP_002342860.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_002342861.1	NMA1543, Insertion element IS1016 transposase, len: 200aa; similar to many eg. TR:Q48208 (EMBL:X58176) from a compound transposon in Haemophilus influenzae (164 aa) fasta scores; E(): 0, 69.6% identity in 161 aa overlap. Similar to others from Neisseria meningitidis eg. NMA1956,fasta scores; E(): 0, 97.5% identity in 200 aa overlap.
YP_002342862.1	NMA1544, unknown, len: 254aa; lies in a region of unusually low GC content, some N-terminal similarity to TR:AAD38961 (EMBL:AF147978) hypothetical protein from Pseudomonas aeruginosa Bacteriophage D3 (170 aa) fasta scores; E(): 0.00049, 31.5% identity in 111 aa overlap.
YP_002342863.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_002342864.1	NMA1546,  carboxy-terminal processing protease, len: 494aa; similar to many eg. TR:Q44879 (EMBL:L37094) carboxy-terminal processing protease from Bartonella bacilliformis (434 aa) fasta scores; E(): 0,41.5% identity in 455 aa overlap. Contains Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF).
YP_002342865.1	NMA1547,  secreted lysine-rich protein, peptidase function, len: 601aa; contains probable N-terminal signal sequence and extensive coiled-coil regions and is largely hydrophilic. Also contains Pfam match to entry PF01551 Peptidase_M37.
YP_002342866.1	NMA1549,  lipoprotein, function unknown,len: 186aa; similar to SW:P08367 (CREA_ECOLI) hypothetical protein from Escherichia coli fasta scores; E(): 1.5e-21,45.9% identity in 146 aa overlap. Contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002342867.1	NMA1550, conserved hypothetical protein, function unknown, len: 182aa; similar to several eg. SW:P52049 (YQGE_ECOLI) hypothetical protein from Escherichia coli (187 aa) fasta scores; E(): 3.2e-31, 44.1% identity in 188 aa overlap.
YP_002342868.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_002342869.1	NMA1552,  hydrolase, len: 218aa; similar to the C-terminal region of TR:Q46978 (EMBL:Z37980) OPET decarboxylase from Escherichia coli (429 aa) fasta scores; E(): 1.4e-13, 30.7% identity in 199 aa overlap. Also similar to many of undefined function particularly TR:Q9ZHI3 (EMBL:AF061446) hypothetical protein from Chromobacterium violaceum (138 aa) fasta scores; E(): 3.5e-26, 56.2% identity in 137 aa overlap. Contains Pfam match to entry PF01557 FAA_hydrolase.
YP_002342870.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_002342871.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
YP_002342872.1	NMA1555, aceF, dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, len: 535aa; similar to many eg. SW:P06959 (ODP2_ECOLI) aceF,dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex from Escherichia coli (629 aa) fasta scores; E(): 0, 56.5% identity in 536 aa overlap. Contains two Pfam matches to entry PF00364 biotin_lipoyl,Biotin-requiring enzymes, Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain) and two Prosite matches to PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
YP_002342873.1	NMA1556, lpdA, dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes), len: 594aa; similar to many eg. SW:P00391 (DLDH_ECOLI) lpdA, dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) from Escherichia coli (473 aa) fasta scores; E(): 0, 63.8% identity in 486 aa overlap. Also similar to TR:Q51188 (EMBL:X84696) from Neisseria meningitidis (594 aa) fasta scores; E(): 0, 97.0% identity in 594 aa overlap. Contains Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzymes; Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase class-I; Prosite match to PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site and Prosite match to PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
YP_002342874.1	NMA1557, unknown, len: 512aa
YP_002342875.1	NMA1558,  TonB-dependent receptor protein,len: 706aa; weakly similar to many TonB-dependent receptor proteins eg. SW:P11461 (FATA_VIBAN) ferric anguibactin receptor precursor from Vibrio anguillarum (726 aa) fasta scores; E(): 8.2e-19, 25.5% identity in 722 aa overlap. Contains Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region.
YP_002342876.1	NMA1559, inositol monophosphate family protein,function unknown, len: 261aa; similar to many other inositol monophosphate family proteins eg. SW:P22783 (SUHB_ECOLI) extragenic suppressor protein from Escherichia coli (267 aa) fasta scores; E(): 0, 44.1% identity in 254 aa overlap. Contains Pfam match to entry PF00459 inositol_P, Inositol monophosphatase family; Prosite match to PS00629 Inositol monophosphatase family signature 1 and Prosite match to PS00630 Inositol monophosphatase family signature 2.
YP_002342877.1	NMA1560, SpoU methylase family protein, len: 292aa; similar to many others of undefined function which carry a Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family eg. TR:P77438 (EMBL:AE000339) hypothetical protein from Escherichia coli (246 aa) fasta scores; E(): 2.7e-17, 36.2% identity in 260 aa overlap. Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family.
YP_002342878.1	NMA1561, unknown, len: 292aa
YP_002342879.1	NMA1562, unknown, len: 113aa; lies in a region of unusually low GC content.
YP_002342880.1	NMA1563, Sun-family protein, len: 418aa; C-terminal similar to many other SUN-family proteins eg. SW:P36929 (SUN_ECOLI) Sun protein from Escherichia coli (429 aa) fasta scores; E(): 1.3e-24, 32.6% identity in 356 aa overlap. Contains Pfam match to entry PF01189 Nol1_Nop2_Sun, NOL1/NOP2/sun family.
YP_002342881.1	NMA1564, unknown, len: 144aa; contains probable coiled-coil in the C-terminal region.
YP_002342882.1	NMA1565, probable aldehyde dehydrogenase, len: 447aa; similar to many eg. SW:P71016 (DHAB_BACSU) betaine aldehyde dehydrogenase from Bacillus subtilis (490 aa) fasta scores; E(): 0, 33.8% identity in 420 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and Prosite match to PS00070 Aldehyde dehydrogenases cysteine active site.
YP_002342883.1	NMA1566, conserved hypothetical protein, len: 237aa; similar to many eg. SW:P25743 (YCHE_ECOLI) hypothetical protein from Escherichia coli (215 aa) fasta scores; E(): 1.2e-20, 33.3% identity in 207 aa overlap.
YP_002342884.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_002342885.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002342886.1	NMA1569,  membrane protein, len: 310aa; similar to SW:Q57273 (YB19_HAEIN) hypothetical protein from Haemophilus influenzae (292 aa) fasta scores; E(): 1.9e-32, 37.6% identity in 295 aa overlap. Contains membrane spanning hydrophobic regions.
YP_002342887.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002342888.1	NMA1571, iron/sulphur-binding oxidoreductase, len: 336aa; similar to many eg. SW:P37911 (ASCD_YERPS) CDP-6-deoxy-delta-3,4-glucoseen reductase from Yersinia pseudotuberculosis (328 aa) fasta scores; E(): 0, 40.4% identity in 329 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains; Pfam match to entry PF00175 oxidored_fad, Oxidoreductase FAD/NAD-binding domain and Prosite match to PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature.
YP_002342889.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate
YP_002342890.1	NMA1573,  pseudouridine synthase, len: 256aa; similar to SW:P35159 (RLUB_BACSU) large subunit pseudouridine synthase B from Bacillus subtilis (229 aa) fasta scores; E(): 1e-21, 39.1% identity in 235 aa overlap. Also similar to many hypothetical proteins eg. SW:P37765 (YCIL_ECOLI) hypothetical protein from Escherichia coli (291 aa) fasta scores; E(): 0, 51.2% identity in 256 aa overlap. Contains Pfam match to entry PF01479 S4, S4 domain and Prosite match to PS01149 RsuA family of pseudouridine synthase signature.
YP_002342891.1	NMA1574,  integral membrane transporter,len: 513aa; weakly similar to several monocarboxylate transporters (eukaryote) eg. SW:P53986 (MOT1_MOUSE) monocarboxylate transporter from Mus musculus (Mouse) (493 aa) fasta scores; E(): 5.7e-10, 23.8% identity in 479 aa overlap. Also similar to TR:Q9ZBV5 (EMBL:AL034443)  integral membrane transporter from Streptomyces coelicolor (446 aa) fasta scores; E(): 0, 50.1% identity in 463 aa overlap.
YP_002342892.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_002342893.1	NMA1576, nadE, NH(3)-dependent NAD synthetase, len: 273aa; similar to many egs. SW:Q58747 (NADE_METJA) probable NH(3)-dependent NAD synthetase from Methanococcus jannaschii (259 aa) fasta scores; E(): 3.9e-22, 35.1% identity in 259 aa overlap and SW:P08164 (NADE_BACSU) NH(3)-dependent NAD synthetase from Bacillus subtilis (272 aa) fasta scores; E(): 4.8e-15, 31.8% identity in 236 aa overlap.
YP_002342894.1	NMA1577, unknown, len: 157aa; similar to SW:P39313 (YTFE_ECOLI) hypothetical protein from Escherichia coli (220 aa) fasta scores; E(): 3.7e-26, 45.7% identity in 151 aa overlap.
YP_002342895.1	NMA1578, trxA, thioredoxin I, len: 129aa; similar to many eg. SW:P00274 (THIO_ECOLI) trxA, thioredoxin I from Escherichia coli (108 aa) fasta scores; E(): 9.1e-27,61.1% identity in 108 aa overlap. Contains Pfam match to entry PF00085 thiored, Thioredoxin and Prosite match to PS00194 Thioredoxin family active site.
YP_002342896.1	NMA1579, unknown, len: 315aa; similar to the C-terminal region of many eg. SW:P44524 (YCBY_HAEIN) hypothetical protein from Haemophilus influenzae (711 aa) fasta scores; E(): 0, 48.4% identity in 316 aa overlap.
YP_002342897.1	NMA1580, probable ATP-dependent RNA helicase, len: 462aa; similar to many eg. SW:P25888 (RHLE_ECOLI) RhlE, ATP-dependent RNA helicase from Escherichia coli (454 aa) fasta scores; E(): 0, 44.0% identity in 466 aa overlap. Contains Pfam match to entry PF00270 DEAD,DEAD/DEAH box helicase; Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain; Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop) and PS00039 DEAD-box subfamily ATP-dependent helicases signature.
YP_002342898.1	NMA1581,  membrane lipoprotein, len: 184aa; contains  N-terminal signal sequence, a  membrane spanning hydrophobic region and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342899.1	NMA1582, unknown, len: 186aa
YP_002342900.1	DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate
YP_002342901.1	binds and unfolds substrates as part of the ClpXP protease
YP_002342902.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_002342903.1	NMA1587, unknown, len: 543aa
YP_002342904.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_002342905.1	NMA1591,  type III restriction/modification system enzyme, len: 940aa; lies alongside a probable modification methylase. C-terminal similar to that from SW:P08764 (T3RE_BPP1) type III restriction/modification system EcoP1 restriction enzyme (970 aa) fasta scores; E(): 0.0039, 22.3% identity in 412 aa overlap. Also highly similar to TR:Q9ZHV5 (EMBL:AF048762) from Neisseria meningitidis (965 aa) fasta scores; E(): 0, 100.0% identity in 933 aa overlap. Lies in a DNA region of unusually low GC content.
YP_002342906.1	NMA1592, lldA, L-lactate dehydrogenase, len: 390aa; almost identical to TR:Q51135 (EMBL:U58911) lldA,L-lactate dehydrogenase from Neisseria meningitidis (390 aa) fasta scores; E(): 0, 99.7% identity in 390 aa overlap. Contains Pfam match to entry PF01070 FMN_dh,FMN-dependent dehydrogenase and Prosite match to PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site.
YP_002342907.1	NMA1593,  conserved hypothetical DNA-binding protein, len: 148aa; similar to many egs. SW:P77484 (YFHP_ECOLI) hypothetical protein from Escherichia coli (162 aa) fasta scores; E(): 1.8e-26,50.7% identity in 146 aa overlap and SW:Q51134 (YLDA_NEIME) hypothetical protein from Neisseria meningitidis (150 aa) fasta scores; E(): 0, 98.5% identity in 131 aa overlap. Contains helix-turn-helix 27-48aa (+2.63 SD).
YP_002342908.1	catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis
YP_002342909.1	NMA1596, NifU-like protein, len: 128aa; similar to many eg. TR:P77310 (EMBL:AE000339) NifU protein from Escherichia coli (128 aa) fasta scores; E(): 0, 84.4% identity in 128 aa overlap. Contains Pfam match to entry PF01592 NifU_N.
YP_002342910.1	NMA1597, HesB-like protein, len: 106aa; similar to many HesB-like proteins eg. SW:P36539 (YFHF_ECOLI) hypothetical protein from Escherichia coli (107 aa) fasta scores; E(): 1.2e-27, 66.7% identity in 105 aa overlap. Contains Pfam match to entry PF01521 HesB-like and Prosite match to PS01152 Hypothetical hesB/yadR/yfhF family signature.
YP_002342911.1	NMA1598, hscB, chaperone protein, len: 166aa; similar to many eg. SW:P36540 (HSCB_ECOLI) hscB, chaperone protein from Escherichia coli (171 aa) fasta scores; E(): 3.2e-17, 41.3% identity in 160 aa overlap. Contains Pfam match to entry PF00226 DnaJ, DnaJ domain.
YP_002342912.1	NMA1599, gyrA, DNA gyrase subunit A, len: 916aa; similar to many eg. SW:P48371 (GYRA_NEIGO) gyrA, DNA gyrase subunit A from Neisseria gonorrhoeae (916 aa) fasta scores; E(): 0, 97.3% identity in 916 aa overlap. Contains Pfam match to entry PF00521 DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A.
YP_002342913.1	NMA1600,  transposase, len: 134aa; similar to (but missing a central 82aa portion) TR:Q9ZIX7 (EMBL:AF007429) transposase from Haemophilus gallinarum (216 aa) fasta scores; E(): 4.3e-22, 51.6% identity in 215 aa overlap. Contains  helix-turn-helix 23-44aa (+3.20 SD).
YP_002342914.1	NMA1603, unknown, len: 183aa; contains probable coiled-coil regions.
YP_002342915.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_002342916.1	NMA1605, probable transcriptional regulator, len: 282aa; weakly similar to SW:P39266 (RPIR_ECOLI) Als operon repressor from Escherichia coli (296 aa) fasta scores; E(): 9.2e-21, 27.9% identity in 258 aa overlap. Also similar to many hypothetical proteins eg. SW:P46118 (YEBK_ECOLI) hypothetical protein from Escherichia coli (289 aa) fasta scores; E(): 0, 42.1% identity in 278 aa overlap. Contains Pfam match to entry PF01380 SIS, SIS domain; Pfam match to entry PF01418 HTH_6,Helix-turn-helix domain, rpiR family and Prosite match to PS00356 Bacterial regulatory proteins, lacI family signature.
YP_002342917.1	catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate
YP_002342918.1	NMA1608, pgl, 6-phosphogluconolactonase, len: 231aa; similar to TR:AAD22666 (EMBL:AF029673) pgl,6-phosphogluconolactonase from Pseudomonas aeruginosa (243 aa) fasta scores; E(): 2.9e-26, 41.7% identity in 218 aa overlap.
YP_002342919.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002342920.1	catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate
YP_002342921.1	catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate
YP_002342922.1	NMA1614, mutY, adenine glycosylase, len: 349aa; similar to many eg. SW:P17802 (MUTY_ECOLI) mutY, adenine glycosylase from Escherichia coli (350 aa) fasta scores; E(): 0, 44.6% identity in 343 aa overlap. Also almost identical to TR:Q9ZF41 (EMBL:AJ001313) mutY, adenine glycosylase from Neisseria meningitidis (346 aa) fasta scores; E(): 0, 99.7% identity in 346 aa overlap. Contains Pfam match to entry PF00730 Endonuclease_3, Endonuclease III and Prosite match to PS00764 Endonuclease III iron-sulfur binding region signature.
YP_002342923.1	NMA1616, unknown, len: 60aa
YP_002342924.1	NMA1617, sodC, superoxide dismutase, len: 186aa; almost identical to SW:Q59623 (SODC_NEIME) sodC,superoxide dismutase from Neisseria meningitidis (186 aa) fasta scores; E(): 0, 99.5% identity in 186 aa overlap. Probably located in the periplasmic space. Contains Pfam match to entry PF00080 sodcu, Copper/zinc superoxide dismutase (SODC) and Prosite match to PS00332 Copper/Zinc superoxide dismutase signature 2.
YP_002342925.1	NMA1620, probable cytolysin secretion ABC transporter, len: 742aa; similar to many involved in cytolysin secretion eg. SW:P26760 (RT1B_ACTPL) RTX-1 toxin secretion ATP-binding protein from Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae) (707 aa) fasta scores; E(): 0, 72.7% identity in 699 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter; Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region; Prosite match to PS00211 ABC transporters family signature and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002342926.1	NMA1621, insertion element IS1016 transposase, len: 179aa; similar to many eg. TR:Q48234 (EMBL:X59756) IS1016 insertion sequence from Haemophilus influenzae (191 aa) fasta scores; E(): 0, 72.6% identity in 175 aa overlap. Similar to others from Neisseria meningitidis eg. NMA2185,fasta scores; E(): 0, 92.7% identity in 179 aa overlap.
YP_002342927.1	NMA1622, unknown, len: 144aa; lies in a region of unusually low GC content.
YP_002342928.1	NMA1623, unknown, len: 73aa; lies in a region of unusually low GC content.
YP_002342929.1	NMA1624,  integral membrane protein, len: 242aa; contains  membrane spanning hydrophobic regions. Lies in a region of unusually low GC content.
YP_002342930.1	NMA1625, probable RTX-family exoprotein, len: 350aa; similar to regions of Neisseria meningitidis iron-regulated proteins egs. N-terminal region of SW:P55127 (FRPC_NEIME) FrpC (1829 aa) fasta scores; E(): 0, 78.8% identity in 146 aa overlap and N-terminal region of SW:P55126 (FRPA_NEIME) FrpA (1115 aa) fasta scores; E(): 0, 41.6% identity in 394 aa overlap. Contains a membrane spanning hydrophobic region.
YP_002342931.1	NMA1626, probable RTX-family exoprotein, len: 697aa; similar to regions of other RTX-family proteins particularly C-terminal region of SW:P55126 (FRPA_NEIME) iron-regulated protein from Neisseria meningitidis (1115 aa) fasta scores; E(): 0, 99.1% identity in 697 aa overlap and C-terminal region of SW:P55127 (FRPC_NEIME) iron-regulated protein from Neisseria meningitidis (1829 aa) fasta scores; E(): 0, 88.0% identity in 685 aa overlap. Contains three Pfam matches to entry PF00353 hemolysinCabind, Hemolysin-type calcium-binding proteins and three Prosite matches to PS00330 Hemolysin-type calcium-binding region signature.
YP_002342932.1	NMA1627, pepN, aminopeptidase N, len: 867aa; similar to many eg. SW:P04825 (AMPN_ECOLI) pepN,aminopeptidase N from Escherichia coli (869 aa) fasta scores; E(): 0, 48.4% identity in 868 aa overlap. Contains Pfam match to entry PF01433 Peptidase_M1, Peptidase family M1 and Prosite match to PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
YP_002342933.1	NMA1628, unknown, len: 264aa; similar to TR:Q9ZLF2 (EMBL:AE001495) hypothetical protein from Helicobacter pylori J99 (276 aa) fasta scores; E(): 1.6e-15, 26.0% identity in 273 aa overlap.
YP_002342934.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
YP_002342935.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_002342936.1	NMA1632, fis, factor-for-inversion-stimulation protein, len: 79aa; similar to many eg. SW:P11028 (FIS_ECOLI) fis, factor-for-inversion-stimulation protein from Escherichia coli (98 aa) fasta scores; E(): 0, 44.0% identity in 75 aa overlap. Contains probable DNA-binding helix-turn-helix motif (+3.80 SD) 54-75aa. Also contains Pfam match to entry PF00158 sigma54, Sigma-54 transcription factors.
YP_002342937.1	NMA1633, conserved hypothetical protein, len: 336aa; similar to many eg. SW:P25717 (YHDG_ECOLI) hypothetical protein from Escherichia coli (321 aa) fasta scores; E(): 0, 53.3% identity in 321 aa overlap. Contains Pfam match to entry PF01207 UPF0034, Uncharacterized protein family UPF0034 and Prosite match to PS01136 Uncharacterized protein family UPF0034 signature.
YP_002342938.1	NMA1634, probable ATP-dependent RNA helicase, len: 457aa; similar to many eg. SW:P25888 (RHLE_ECOLI) ATP-dependent RNA helicase from Escherichia coli (454 aa) fasta scores; E(): 0, 46.2% identity in 457 aa overlap. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase; Pfam match to entry PF00271 helicase_C,Helicases conserved C-terminal domain; Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop) and Prosite match to PS00039 DEAD-box subfamily ATP-dependent helicases signature.
YP_002342939.1	NMA1635, unknown, len: 375aa
YP_002342940.1	NMA1636, unknown, len: 292aa
YP_002342941.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_002342942.1	NMA1639, probable integral membrane protein, len: 417aa; contains probable membrane spanning hydrophobic regions.
YP_002342943.1	NMA1640,  aminopeptidase, len: 659aa; weakly similar to many both prokaryote and eukaryote eg. TR:Q95333 (EMBL:U55039) aminopeptidase P from Sus scrofa (Pig) (673 aa) fasta scores; E(): 0, 34.8% identity in 632 aa overlap. Contains Pfam match to entry PF00557 Peptidase_M24, metallopeptidase family M24.
YP_002342944.1	NMA1641, probable insertion element IS1106 transposase, len: 273aa; similar to many transposases particularly SW:Q00840 (TRA6_NEIME) insertion element IS1106 transposase from Neisseria meningitidis (288 aa) fasta scores; E(): 0, 80.8% identity in 265 aa overlap.
YP_002342945.1	NMA1642, porA, porin, class I outer membrane protein, len: 395aa; highly similar to many eg. TR:Q51240 (EMBL:X52995) porA, class I outer membrane protein from Neisseria meningitidis (392 aa) fasta scores; E(): 0,95.7% identity in 395 aa overlap. Contains Pfam match to entry PF00267 Gram-ve_porins, General diffusion Gram-negative porins and Prosite match to PS00576 General diffusion Gram-negative porins signature. Also similar to NM398, porB (43.7% identity in 398 aa overlap)
YP_002342946.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002342947.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_002342948.1	NMA1645,  lipoprotein, len: 177aa; similar to many over a specific region which corresponds to a conserved domain of unknown function found in lipoproteins eg. SW:Q47151 (YAFL_ECOLI) hypothetical lipoprotein from Escherichia coli (249 aa) fasta scores; E(): 0, 37.2% identity in 156 aa overlap. Contains Pfam match to entry PF00877 NLPC_P60, NLP/P60 family and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002342949.1	NMA1646, phopholipase D-family protein, len: 525aa; similar to many of undefined function eg. SW:P75919 (YMDC_ECOLI) hypothetical protein from Escherichia coli (493 aa) fasta scores; E(): 0, 48.7% identity in 460 aa overlap. Contains two Pfam matches to entry PF00614 PLDc,Phospholipase D. Active site motif. Also contains a membrane spanning hydrophobic region.
YP_002342950.1	NMA1647, probable integral membrane protein, len: 513aa; similar to many with  membrane spanning hydrophobic regions eg. SW:P31474 (YIEO_ECOLI) hypothetical protein from Escherichia coli (475 aa) fasta scores; E(): 0, 43.0% identity in 451 aa overlap. Contains  membrane spanning hydrophobic regions.
YP_002342951.1	NMA1648, conserved hypothetical protein, len: 259aa; similar to others of undefined function eg. TR:O24951 (EMBL:AE000535) conserved hypothetical secreted protein from Helicobacter pylori (242 aa) fasta scores; E(): 0, 40.8% identity in 240 aa overlap.
YP_002342952.1	NMA1649, conserved hypothetical protein, len: 233aa; similar to TR:O24949 (EMBL:AE000535) hypothetical protein from Helicobacter pylori (211 aa) fasta scores; E(): 1.9e-11, 29.0% identity in 217 aa overlap.
YP_002342953.1	NMA1650, conserved hypothetical iron-sulphur protein, len: 484aa; similar to many eg. TR:O24950 (EMBL:AE000535) conserved hypothetical iron-sulphur protein from Helicobacter pylori (481 aa) fasta scores; E(): 0, 44.4% identity in 450 aa overlap. Contains Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and two Prosite matches to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
YP_002342954.1	NMA1651, purE, phosphoribosylaminoimidazole carboxylase catalytic subunit, len: 161aa; similar to many eg. SW:P12044 (PUR6_BACSU) purE,phosphoribosylaminoimidazole (162 aa) fasta scores; E(): 0, 66.2% identity in 151 aa overlap. Contains Pfam match to entry PF00731 AIRC, AIR carboxylase, score 300.10,E-value 2.8e-86.
YP_002342955.1	NMA1652,  periplasmic protein, len: 238aa; contains N-terminal signal sequence. Also contains probable coiled-coil region.
YP_002342956.1	NMA1653,  methyltransferase, len: 222aa; similar to many methyltransferases egs. TR:Q50859 (EMBL:U24657) O-methyltransferase from DNA-binding antibiotic biosynthesis cluster of Myxococcus xanthus (220 aa) fasta scores; E(): 2.4e-26, 39.3% identity in 219 aa overlap. Contains Pfam match to entry PF01596 Methyltransf_3.
YP_002342957.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_002342958.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_002342959.1	NMA1657, conserved hypothetical protein, len: 111aa; similar to many eg. SW:P44711 (YBAB_HAEIN) hypothetical protein from Haemophilus influenzae (109 aa) fasta scores; E(): 4.8e-19, 58.3% identity in 108 aa overlap. Contains probable coiled-coil region towards the N-terminus.
YP_002342960.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_002342961.1	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis
YP_002342962.1	NMA1660, rep, ATP-dependent DNA helicase, len: 671aa; similar to many eg. SW:P09980 (REP_ECOLI) rep,ATP-deepndent DNA helicase from Escherichia coli (673 aa) fasta scores; E(): 0, 48.1% identity in 669 aa overlap. Contains Pfam match to entry PF00580 UvrD-helicase,UvrD/REP helicase and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002342963.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_002342964.1	NMA1664, probable ferredoxin NADP+ reductase, len: 259aa; similar to many ferredoxin NADP+ reductases eg. SW:P28861 (FENR_ECOLI) ferredoxin NADP+ reductase from Escherichia coli (247 aa) fasta scores; E(): 3.7e-22,32.3% identity in 254 aa overlap. Contains Pfam match to entry PF00175 oxidored_fad, Oxidoreductase FAD/NAD-binding domain.
YP_002342965.1	NMA1665,  DNA polymerase III subunit, len: 470aa; similar to many eg. the central region of SW:P13267 (DPO3_BACSU) DNA polymerase III alpha chain from Bacillus subtilis (1437 aa) fasta scores; E(): 1.1e-11, 30.6% identity in 170 aa overlap. Contains Pfam match to entry PF00929 Exonuclease, Exonuclease.
YP_002342966.1	NMA1666, unknown, len: 391aa; similar to TR:O25465 (EMBL:AE000589) hypothetical protein from Helicobacter pylori (363 aa) fasta scores; E(): 1.2e-23, 30.7% identity in 387 aa overlap.
YP_002342967.1	NMA1667,  inner membrane protein, len: 182aa; contains a  membrane spanning hydrophobic region close to the N-terminus.
YP_002342968.1	NMA1668,  ferredoxin, len: 498aa; similar to many ferredoxin-like proteins eg. SW:P18396 (FIXG_RHIME) FixG from Rhizobium meliloti (524 aa) fasta scores; E(): 0, 33.8% identity in 461 aa overlap. Contains Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and Prosite match to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. Contains  membrane spanning hydrophobic regions.
YP_002342969.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002342970.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_002342971.1	NMA1671, conserved hypothetical protein, len: 307aa; similar to many eg. SW:P71360 (YHBE_HAEIN) hypothetical protein from Haemophilus influenzae (306 aa) fasta scores; E(): 0, 48.2% identity in 307 aa overlap. Contains two Pfam matches to entry PF00892 DUF6, Integral membrane protein.
YP_002342972.1	NMA1672, ssb, single-stranded binding protein, len: 174aa; similar to many eg. SW:P02339 (SSB_ECOLI) ssb,single-stranded binding protein from Escherichia coli (177 aa) fasta scores; E(): 1.3e-22, 48.1% identity in 181 aa overlap. Contains Pfam match to entry PF00436 SSB,Single-strand binding protein family; Prosite match to PS00736 Single-strand binding protein family signature 2 and Prosite match to PS00735 Single-strand binding protein family signature 1.
YP_002342973.1	NMA1673, probable integral membrane transporter,len: 461aa; similar to many proposed membrane transporters eg. TR:O67276 (EMBL:AE000729) transporter (major facilitator family) from Aquifex aeolicus (392 aa) fasta scores; E(): 0, 41.6% identity in 382 aa overlap. Contains Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter and Prosite match to PS00216 Sugar transport proteins signature 1. Also contains probable membrane spanning hydrophobic regions.
YP_002342974.1	NMA1674,  transglycosylase, len: 207aa; regions of weak similarity to many eg. SW:P03810 (SLT_ECOLI) soluble lytic murein transglycosylase precursor from Escherichia coli (645 aa) fasta scores; E(): 0.1, 27.7% identity in 141 aa overlap. Contains Pfam match to entry PF01464 SLT, Transglycosylase SLT domain.
YP_002342975.1	NMA1675, conserved hypothetical protein, len: 138aa; similar to others eg. SW:Q47152 (YAFM_ECOLI) hypothetical protein from Escherichia coli (165 aa) fasta scores; E(): 9.6e-30, 52.0% identity in 127 aa overlap. Also highly similar to NMA0532 form another region of the Neisseria meningitidis chromosome (138 aa) fasta scores; E(): 0, 99.3% identity in 138 aa overlap. Lies within a region of unusually low GC content.
YP_002342976.1	NMA1679, ppx/gppA, exopolyphosphatase, len: 502aa; similar to many exophosphatases including SW:P29014 (PPX_ECOLI) ppx, exopolyphosphatase from Escherichia coli (512 aa) fasta scores; E(): 0, 36.5% identity in 501 aa overlap and SW:P25552 (GPPA_ECOLI) guanosine pentaphosphate phosphohydrolase from Escherichia coli (494 aa) fasta scores; E(): 0, 34.3% identity in 499 aa overlap.
YP_002342977.1	NMA1681, unknown, len: 113aa
YP_002342978.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002342979.1	NMA1683, clpB, ClpB protein, len: 859aa; similar to many eg. SW:P03815 (CLPB_ECOLI) ClpB protein (ATPase subunit of clp protease) from Escherichia coli (857 aa) fasta scores; E(): 0, 66.4% identity in 857 aa overlap. Contains Pfam match to entry PF00495 clpA_B, Chaperonin clpA/B; two Prosite matches to PS00017 ATP/GTP-binding site motif A (P-loop); Prosite match to PS00870 Chaperonins clpA/B signature 1 and Prosite match to PS00871 Chaperonins clpA/B signature 2. Also contains coiled-coil regions.
YP_002342980.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
YP_002342981.1	NMA1685,  tautomerase, len: 69aa; similar to many eg. SW:P49172 (DMPI_PSESP) 4-oxalocrotonate tautomerase from Pseudomonas sp. (strain CF600) (62 aa) fasta scores; E(): 0.32, 32.3% identity in 65 aa overlap. Also similar to SW:P45418 (YKDK_ERWCH) hypothetical protein from Erwinia chrysanthemi (73 aa) fasta scores; E(): 2.2e-15, 65.7% identity in 67 aa overlap. Contains Pfam match to entry PF01361 Tautomerase, Tautomerase enzyme.
YP_002342982.1	NMA1686,  periplasmic protein, len: 268aa; similar to SW:P44196 (YE27_HAEIN) hypothetical protein from Haemophilus influenzae (278 aa) fasta scores; E(): 0,44.6% identity in 269 aa overlap. Seems to have a cleavable N-term signal seq.
YP_002342983.1	NMA1687, probable glutamate dehydrogenase, len: 421aa; similar to many eg. SW:P27346 (DHE2_CLODI) NAD-specific glutamate dehydrogenase (421 aa) fasta scores; E(): 0, 56.6% identity in 422 aa overlap. Contains Pfam match to entry PF00208 GLFV_dehydrog,Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; and Prosite match to PS00074 Glu / Leu / Phe / Val dehydrogenases active site.
YP_002342984.1	catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate
YP_002342985.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_002342986.1	NMA1691,  acyl-CoA hydrolase, len: 160aa; weakly similar to the N-terminal region of TR:O08652 (EMBL:D88891) acyl-CoA hydrolase from Rattus norvegicus (Rat) (343 aa) fasta scores; E(): 1.7e-10, 32.2% identity in 152 aa overlap. Also similar to SW:O05729 (VDLD_HELPY) VdlD protein from Helicobacter pylori (174 aa) fasta scores; E(): 5.1e-30, 56.5% identity in 138 aa overlap. Contains Pfam match to entry PF01662 Acyl-CoA_hydro.
YP_002342987.1	NMA1692,  membrane peptidase, len: 415aa; similar to the C-terminal region of proposed lipoproteins eg. SW:P33648 (NLPD_ECOLI) lipoprotein from Escherichia coli (379 aa) fasta scores; E(): 3.3e-16, 36.4% identity in 321 aa overlap. Also similar to SW:P44833 (LPPB_HAEIN) outer membrane antigenic lipoprotein from Haemophilus influenzae (405 aa) fasta scores; E(): 1.4e-14, 30.5% identity in 446 aa overlap. Contains Pfam match to entry PF01551 Peptidase_M37,  peptidoglycan binding domain; Pfam match to entry PF01476 PG_binding_2,  peptidoglycan binding domain; Pfam match to entry PF01476 PG_binding_2, peptidoglycan binding domain and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002342988.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_002342989.1	NMA1694, conserved hypothetical integral membrane protein, len: 526aa; similar to many hypothetical proteins eg. SW:P76262 (YOAE_ECOLI) hypothetical protein from Escherichia coli (518 aa) fasta scores; E(): 0, 46.4% identity in 521 aa overlap. Contains two Pfam match to entry PF00571 CBS, CBS domain and probable membrane spanning hydrophobic regions.
YP_002342990.1	NMA1695,  fimbrial assembly protein, len: 262aa; similar to several fimbrial assembly proteins SW:P17834 (FMBI_BACNO) fimbrial assembly protein from Bacteroides nodosus (257 aa) fasta scores; E(): 0, 39.0% identity in 254 aa overlap.
YP_002342991.1	NMA1696, gabD, succinate semialdehyde dehydrogenase, len: 477aa; similar to many eg. SW:P25526 (GABD_ECOLI) gabD, succinate semialdehyde dehydrogenase from Escherichia coli (482 aa) fasta scores; E(): 0, 61.5% identity in 455 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase; Prosite match to PS00070 Aldehyde dehydrogenases cysteine active site and Prosite match to PS00687 Aldehyde dehydrogenases glutamic acid active site.
YP_002342992.1	NMA1697,  lipoprotein, len: 126aa; contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site
YP_002342993.1	NMA1698, probable integral membrane protein (CstA-like), len: 693aa; strongly similar to SW:P15078 (CSTA_ECOLI) CstA, carbon starvation protein from Escherichia coli (701 aa) fasta scores; E(): 0, 62.1% identity in 683 aa overlap. Contains probable membrane-spanning hydrophobic regions.
YP_002342994.1	NMA1700,  outer membrane substrate binding protein, len: 922aa; weakly similar to several transferrin-binding proteins from Neisseria meningitidis eg. SW:Q06987 (TB12_NEIME) transferrin-binding protein (908 aa) fasta scores; E(): 1.9e-07, 23.5% identity in 833 aa overlap. Also similar to SW:P45114 (YC17_HAEIN) probable TonB receptor protein from Haemophilus influenzae (913 aa) fasta scores; E(): 0, 52.4% identity in 931 aa overlap. Contains Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop) and Prosite match to PS01156 TonB-dependent receptor proteins signature 2. Also contains a  N-terminal signal sequence.
YP_002342995.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_002342996.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_002342997.1	NMA1703, conserved hypothetical protein, len: 154aa; similar to many eg. TR:O06153 (EMBL:Z95554) hypothetical protein from Mycobacterium tuberculosis (146 aa) fasta scores; E(): 9.3e-10, 34.5% identity in 148 aa overlap. Contains Pfam match to entry PF00582 Usp,Universal stress protein family.
YP_002342998.1	NMA1704, conserved hypothetical protein, len: 258aa; similar to SW:Q46927 (YGDL_ECOLI) hypothetical protein from Escherichia coli (268 aa) fasta scores; E(): 0, 50.6% identity in 253 aa overlap. Contains Pfam match to entry PF00899 ThiF_family, ThiF family.
YP_002342999.1	NMA1705, unknown, len: 284aa; similar to many hypothetical proteins eg. SW:P35154 (YPUG_BACSU) hypothetical protein from Bacillus subtilis (251 aa) fasta scores; E(): 2.4e-16, 40.5% identity in 247 aa overlap.
YP_002343000.1	catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate
YP_002343001.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_002343002.1	NMA1708, unknown, len: 472aa; N-terminal region highly similar to one previously partially sequenced ie. TR:AAD24875 (EMBL:AF073777) hypothetical protein from Neisseria meningitidis (235 aa) fasta scores; E(): 0,90.8% identity in 196 aa overlap.
YP_002343003.1	NMA1709, binding-protein-dependent transport systems inner membrane protein, len: 248aa; similar to many eg. SW:P41074 (GLTJ_ECOLI) glutamate/aspartate transport system permease from Escherichia coli (246 aa) fasta scores; E(): 0, 31.2% identity in 231 aa overlap. Contains Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component and Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains  membrane-spanning hydrophobic regions
YP_002343004.1	NMA1710,  nuclease, len: 233aa; similar to SW:P29769 (NUC_SHIFL) micrococcal nuclease from Shigella flexneri (174 aa) fasta scores; E(): 7e-08, 35.8% identity in 151 aa overlap. Contains Pfam match to entry PF00565 SNase, Staphylococcal nuclease homologues and Prosite match to PS01123 Thermonuclease family signature 1.
YP_002343005.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
YP_002343006.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
YP_002343007.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_002343008.1	NMA1714, dnaQ, DNA polymerase III, epsilon chain,len: 244aa; similar to many eg. SW:P03007 (DP3E_ECOLI) dnaQ, DNA polymerase III, epsilon chain from Escherichia coli (243 aa) fasta scores; E(): 0, 45.5% identity in 242 aa overlap. Contains Pfam match to entry PF00929 Exonuclease, Exonuclease.
YP_002343009.1	NMA1715,  integral membrane protein, len: 436aa; weakly similar to many of undefined function eg. TR:O84647 (EMBL:AE001334) proposed efflux protein from Chlamydia trachomatis (559 aa) fasta scores; E(): 1.7e-16,25.1% identity in 442 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343010.1	NMA1716,  inner membrane protein, len: 62aa; contains a  non-cleavable N-terminal signal sequence.
YP_002343011.1	NMA1717, unknown, len: 99aa
YP_002343012.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_002343013.1	two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm
YP_002343014.1	NMA1720, unknown, len: 156aa
YP_002343015.1	NMA1721,  transferase, len: 276aa; similar to a region from many phytoene synthases eg. SW:P37272 (PSY_CAPAN) phytoene synthase from Capsicum annuum (Bell pepper) (419 aa) fasta scores; E(): 3e-17, 31.1% identity in 273 aa overlap. Also similar to hypothetical proteins eg. TR:O06001 (EMBL:X86552) hypothetical protein from Bradyrhizobium japonicum (294 aa) fasta scores; E(): 6.6e-23, 35.8% identity in 257 aa overlap. Contains Pfam match to entry PF00494 SQS_PSY, Squalene and phytoene synthases.
YP_002343016.1	NMA1722,  cis-trans isomerase, len: 160aa; similar to many eg. SW:P30856 (SLYD_ECOLI) SlyD,peptidyl-prolyl cis-trans isomerase from Escherichia coli (196 aa) fasta scores; E(): 8.8e-19, 42.3% identity in 163 aa overlap.
YP_002343017.1	NMA1723,  proline-rich repeat protein, len: 110aa; contains 7x K(LH)(PL)(LP)LK(HL)(LP)(PL)P repeat at 20-89aa.
YP_002343018.1	NMA1724, hypothetical protein, len: 455aa; C-terminal strongly similar to TR:Q51113 (EMBL:U23782) hypothetical protein (FRAGMENT) from Neisseria meningitidis (195 aa) fasta scores; E(): 0, 85.1% identity in 195 aa overlap. N-terminal region contains Pfam match to entry PF01565 FAD_binding_4.
YP_002343019.1	NMA1725,  virulence associated protein,len: 642aa; strongly similar to TR:Q51112 (EMBL:U23782) from Neisseria meningitidis, designated as similar to Shigella flexneri VirG protein (682 aa) fasta scores; E(): 0, 81.7% identity in 650 aa overlap.
YP_002343020.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_002343021.1	NMA1727, rfaF, ADP-heptose:LPS heptosyltransferase II, len: 455aa; similar to many eg. TR:Q51063 (EMBL:Z37141) rfaF, ADP-heptose:LPS heptosyltransferase II from Neisseria gonorrhoeae (336 aa) fasta scores; E(): 0,96.4% identity in 336 aa overlap. Contains Pfam match to entry PF01075 Heptosyltranf, Heptosyltransferase.
YP_002343022.1	NMA1728,  methylated-DNA-protein-cysteine methyltransferase, len: 289aa; C-terminal region similar to the methylated-DNA-protein-cysteine methyltransferase domain of many eg. SW:P19220 (ADAB_BACSU) methylated-DNA-protein-cysteine methyltransferase from Bacillus subtilis (179 aa) fasta scores; E(): 1.2e-20,44.0% identity in 141 aa overlap. C-terminal region contains Pfam match to entry PF01035 Methyltransf_1,6-O-methylguanine DNA methyltransferase and Prosite match to PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
YP_002343023.1	NMA1729,  outer membrane protein, len: 186aa; similar to many hypothetical proteins especially in the N-terminal region eg. SW:P77368 (YBCL_ECOLI) hypothetical protein from Escherichia coli (183 aa) fasta scores; E(): 2.5e-13, 46.0% identity in 113 aa overlap.
YP_002343024.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_002343025.1	NMA1731, conserved hypothetical protein, len: 206aa; similar to SW:P44013 (Y552_HAEIN) hypothetical protein from Haemophilus influenzae (207 aa) fasta scores; E(): 0, 59.6% identity in 203 aa overlap.
YP_002343026.1	NMA1732, conserved hypothetical protein, len: 169aa; similar to SW:P43971 (Y243_HAEIN) hypothetical protein from Haemophilus influenzae (172 aa) fasta scores; E(): 0, 49.7% identity in 169 aa overlap.
YP_002343027.1	NMA1733, H.8 outer membrane protein, len: 183aa; strongly similar to SW:P07212 (H8_NEIME) H.8 outer membrane protein from Neisseria meningitidis (183 aa) fasta scores; E(): 0, 96.7% identity in 183 aa overlap. Contains Pfam match to entry PF00127 copper-bind, Copper binding proteins, plastocyanin/azurin family and Prosite match to PS00196 Type-1 copper (blue) proteins signature.
YP_002343028.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_002343029.1	synthesizes RNA primers at the replication forks
YP_002343030.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_002343031.1	NMA1738, insertion element IS1106 transposase, len: 283aa; similar to other copies eg. SW:Q00840 (TRA6_NEIME) transposase for insertion element IS1106 from Neisseria meningitidis (288 aa) fasta scores; E(): 0, 74.3% identity in 230 aa overlap.
YP_002343032.1	NMA1739, lbpA, lactoferrin binding protein A, len: 944aa; similar to many eg. TR:Q51187 (EMBL:X79838) lbpA,lactoferrin binding protein A from Neisseria meningitidis (940 aa) fasta scores; E(): 0, 95.4% identity in 944 aa overlap. Contains Pfam match to entry PF00593 TonB_boxC,TonB dependent receptor C-terminal region and Prosite match to PS01156 TonB-dependent receptor proteins signature 2.
YP_002343033.1	NMA1740, lbpB, lactoferrin-binding protein, len: 741aa; similar to many eg. TR:AAD31768 (EMBL:AF123380) lbpB, lactoferrin-binding protein from Neisseria meningitidis (741 aa) fasta scores; E(): 0, 83.4% identity in 749 aa overlap. Contains Pfam match to entry PF01298 Lipoprotein_5, Transferrin binding protein and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Contains potential coiled-coil region around 460aa.
YP_002343034.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_002343035.1	NMA1743, fadD, long-chain-fatty-acid--CoA-ligase,len: 556aa; similar to many eg. SW:P29212 (LCFA_ECOLI) fadD, long-chain-fatty-acid--CoA-ligase from Escherichia coli (561 aa) fasta scores; E(): 0, 56.6% identity in 557 aa overlap. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme; Prosite match to PS00455  AMP-binding domain signature and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002343036.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_002343037.1	NMA1745, unknown, len: 157 aa; similar to hypothetical proteins e.g. TR:O67294 (EMBL:AE000731) Aquifex aeolicus AQ_1253 (151 aa), fasta scores; E(): 1.1e-09, 33.1% identity in 151 aa overlap
YP_002343038.1	NMA1746, dgk, diacylglycerol kinase, len: 127aa; similar to many eg. SW:P00556 (KDGL_ECOLI) dgk,diacylglycerol kinase from Escherichia coli (121 aa) fasta scores; E(): 3.6e-12, 43.5% identity in 108 aa overlap. Contains Pfam match to entry PF01219 DAGK_prokar,Prokaryotic diacylglycerol kinase. Also contains  membrane-spanning hydrophobic regions.
YP_002343039.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
YP_002343040.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002343041.1	NMA1749, glpR, glycerol 3-phosphate regulon repressor, len: 257aa; similar to many eg. SW:P09392 (GLPR_ECOLI) glpR, glycerol 3-phosphate regulon repressor (252 aa) fasta scores; E(): 0, 43.9% identity in 253 aa overlap. Contains Pfam match to entry PF00455 deoR,Bacterial regulatory proteins, deoR family and Prosite match to PS00894 Bacterial regulatory proteins, deoR family signature. Also contains  helix-turn-helix 22-43aa (+4.67 SD).
YP_002343042.1	NMA1750, hypothetical integral membrane protein,len: 300aa; similar to many hypothetical proteins eg. TR:BAA35588 (EMBL:D90724) hypothetical protein from Escherichia coli (299 aa) fasta scores; E(): 0, 39.0% identity in 300 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343043.1	NMA1751,  gntR-family transcriptional regulator, len: 238aa; similar to many proposed transcriptional regulators eg. TR:CAB46933 (EMBL:AL096822)  gntR-family transcriptional regulator from Streptomyces coelicolor (216 aa) fasta scores; E(): 5.8e-13, 32.7% identity in 199 aa overlap. Contains Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family and helix-turn-helix 50-71aa (+3.34 SD).
YP_002343044.1	NMA1753, unknown, len: 116aa; similar to many of undefined function eg. SW:P24246 (YHFA_ECOLI) hypothetical protein from Escherichia coli (134 aa) fasta scores; E(): 1e-23, 51.8% identity in 114 aa overlap.
YP_002343045.1	NMA1754, unknown, len: 223aa
YP_002343046.1	NMA1755, purN, phosphoribosylglycinamide transformylase, len: 208aa; similar to many eg. SW:P08179 (PUR3_ECOLI) purN, phosphoribosylglycinamide transformylase from Escherichia coli (212 aa) fasta scores; E(): 0, 51.8% identity in 193 aa overlap. Contains Pfam match to entry PF00551 formyl_transf, Formyl transferase.
YP_002343047.1	NMA1756,  peptidyl-prolyl isomerase, len: 272aa; similar to many eg. TR:O08437 (EMBL:U56832) peptidyl-prolyl isomerase from Aeromonas hydrophila (268 aa) fasta scores; E(): 5.4e-30, 44.5% identity in 265 aa overlap. Contains Pfam match to entry PF00254 FKBP,FKBP-type peptidyl-prolyl cis-trans isomerases; Pfam match to entry PF01346 FKBP_N, Domain amino terminal to FKBP-type peptidyl-prolyl isomerase and Prosite match to PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
YP_002343048.1	NMA1757, holC, DNA polymerase III chi subunit, len: 146aa; similar to SW:P28905 (HOLC_ECOLI) holC, DNA polymerase III chi subunit from Escherichia coli (147 aa) fasta scores; E(): 8.9e-05, 29.9% identity in 147 aa overlap.
YP_002343049.1	NMA1758, pepA, aminopeptidase A, len: 468aa; similar to many aminopeptidases eg. SW:P11648 (AMPA_ECOLI) pepA, aminopeptidase A from Escherichia coli (503 aa) fasta scores; E(): 0, 50.3% identity in 362 aa overlap. Contains Pfam match to entry PF00883 Peptidase_M17,Cytosol aminopeptidase family and Prosite match to PS00631 Cytosol aminopeptidase signature.
YP_002343050.1	NMA1759, conserved hypothetical integral membrane protein, len: 371aa; similar to SW:P39340 (YJGP_ECOLI) hypothetical protein from Escherichia coli (366 aa) fasta scores; E(): 2.1e-26, 29.2% identity in 360 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343051.1	NMA1760, conserved hypothetical integral membrane protein, len: 356aa; similar to many eg. SW:P39341 (YJGQ_ECOLI) hypothetical protein from Escherichia coli (361 aa) fasta scores; E(): 1.1e-32, 28.8% identity in 354 aa overlap. Contains  membrane-spanning hydrophobic regions
YP_002343052.1	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
YP_002343053.1	catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway
YP_002343054.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_002343055.1	NMA1764, conserved hypothetical protein, len: 97aa; similar to many eg. SW:P94425 (YCNE_BACSU) hypothetical protein from Bacillus subtilis (95 aa) fasta scores; E(): 4.5e-12, 48.6% identity in 74 aa overlap.
YP_002343056.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_002343057.1	NMA1766, ilvI, acetolactate synthase isozyme III large subunit, len: 575aa; similar to many eg. SW:P00893 (ILVI_ECOLI) ilvI, acetolactate synthase isozyme III large subunit from Escherichia coli (574 aa) fasta scores; E(): 0, 57.5% identity in 572 aa overlap. Contains Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes and Prosite match to PS00187 Thiamine pyrophosphate enzymes signature.
YP_002343058.1	NMA1767,  lipoprotein, len: 217aa; contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Some similarity to several hypothetical proteins eg. TR:Q9ZCW7 (EMBL:AJ235272) hypothetical protein from Rickettsia prowazekii (205 aa) fasta scores; E(): 1.7e-19, 43.9% identity in 139 aa overlap.
YP_002343059.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
YP_002343060.1	NMA1769, unknown, len: 229aa
YP_002343061.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_002343062.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_002343063.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
YP_002343064.1	NMA1773, unknown, len: 289aa; similar to many of undefined function eg. TR:Q9ZLJ4 (EMBL:AE001491) dehydrogenase from Helicobacter pylori (285 aa) fasta scores; E(): 0, 44.2% identity in 285 aa overlap.
YP_002343065.1	NMA1774,  transcriptional regulator, len: 120aa; similar to many of undefined function eg. SW:P42193 (PAPX_ECOLI) Papx protein from Escherichia coli (164 aa) fasta scores; E(): 0.024, 27.6% identity in 116 aa overlap. Contains Pfam match to entry PF01047 MarR, MarR family and  helix-turn-helix motif 45-66aa (+3.67 SD).
YP_002343067.1	NMA1777,  integral membrane protein, len: 287aa; contains  membrane-spanning hydrophobic regions.
YP_002343068.1	SohB; periplasmic protein; member of the peptidase S49 family
YP_002343069.1	NMA1779, pgsA,CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, len: 187aa; similar to many eg. SW:P06978 (PGSA_ECOLI) pgsA,CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase from Escherichia coli (181 aa) fasta scores; E(): 2.3e-31, 51.1% identity in 182 aa overlap. Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase and Prosite match to PS00379 CDP-alcohol phosphatidyltransferases signature.
YP_002343070.1	NMA1781, doubtful CDS, function unknown, len: 100aa
YP_002343071.1	NMA1782, conserved hypothetical protein, len: 111aa; similar to many eg. SW:Q57498 (YA53_HAEIN) hypothetical protein from Haemophilus influenzae (113 aa) fasta scores; E(): 6.3e-29, 75.9% identity in 112 aa overlap.
YP_002343072.1	NMA1783, AraC-family transcriptional regulator,len: 301aa; similar to many eg. TR:AAD44693 (EMBL:AF128627) MtrA AraC-like protein from Neisseria gonorrhoeae (301 aa) fasta scores; E(): 0, 94.0% identity in 301 aa overlap. Contains Pfam match to entry PF00165 HTH_2, Bacterial regulatory helix-turn-helix proteins,araC family.
YP_002343073.1	NMA1784, unknown, len: 191aa
YP_002343074.1	NMA1785, conserved hypothetical integral membrane protein,  transport function, len: 300aa; similar to many eg. TR:O83951 (EMBL:AE001266) conserved hypothetical integral membrane protein from Treponema pallidum (294 aa) fasta scores; E(): 2.4e-15, 31.4% identity in 271 aa overlap. Contains Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains  membrane-spanning hydrophobic regions.
YP_002343075.1	NMA1786,  polyamine permease substrate-binding protein, len: 376aa; similar to many eg. SW:P31133 (POTF_ECOLI) putrescine-binding periplasmic protein (370 aa) fasta scores; E(): 0, 43.2% identity in 347 aa overlap. Also similar to NMA0831 (fasta scores; E(): 0, 60.8% identity in 380 aa overlap) and NMA2023 fasta scores; (E(): 0, 55.2% identity in 377 aa overlap) from Neisseria meningitidis. Contains a  cleavable N-terminal signal sequence.
YP_002343076.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002343077.1	NMA1789, unknown, len: 243aa; lies in a DNA region of unusually low GC content.
YP_002343078.1	NMA1791, unknown, len: 803aa; similar to but approx. 110aa shorter than TR:O30579 (EMBL:AF012532) hypothetical protein from Bacillus subtilis (879 aa) fasta scores; E(): 0, 38.5% identity in 816 aa overlap.
YP_002343079.1	NMA1792, unknown, len: 422aa; lies in a DNA region of unusually low GC content.
YP_002343080.1	NMA1793, unknown, len: 103aa; lies in a DNA region of unusually low GC content.
YP_002343081.1	NMA1794, unknown, len: 66aa; lies in a DNA region of unusually low GC content.
YP_002343082.1	NMA1795, unknown, len: 76aa; lies in a DNA region of unusually low GC content and contains membrane-spanning hydrophobic regions.
YP_002343083.1	NMA1796, unknown, len: 100aa; lies in a DNA region of unusually low GC content.
YP_002343084.1	NMA1797, tspB, TspB protein, len: 539aa; strongly similar to TR:O87783 (EMBL:AJ010115) a potent T-cell and B-cell stimulating Neisseria-specific antigen from Neisseria meningitidis (504 aa) fasta scores; E(): 0,85.6% identity in 465 aa overlap.
YP_002343085.1	NMA1798,  integral membrane protein, len: 94aa; contains a  non-cleavable N-terminal signal sequence and membrane-spanning hydrophobic region.
YP_002343086.1	NMA1799, unknown, len: 395aa; similar to TR:O82966 (EMBL:AB015669) hypothetical protein from Burkholderia solanacearum (364 aa) fasta scores; E(): 1.1e-20; 31.0% identity in 358 aa overlap.
YP_002343087.1	NMA1800,  invertase/transposase, len: 318aa; similar to other proposed invertases eg. TR:P72078 (EMBL:U65994) pilin gene inverting protein homolog from Neisseria gonorrhoeae (320 aa) fasta scores; E(): 0, 42.6% identity in 317 aa overlap. Contains Pfam match to entry PF01548 Transposase_9.
YP_002343088.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_002343089.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002343090.1	NMA1803,  two component sensor kinase, len: 505aa; similar to many eg. TR:Q51530 (EMBL:L22436) pilin transcripoitnal regulator (530 aa) fasta scores; E(): 4.3e-22; 25.8% identity in 496 aa overlap. Also strongly similar to TR:P72076 (EMBL:U65994) Rsp from Neisseria gonorrhoeae (572 aa) fasta scores; E(): 0, 75.5% identity in 335 aa overlap. Contains  membrane-spanning hydrophobic regions in the N-terminal region and Pfam match to entry PF00512 signal, Signal carboxyl-terminal domain in the C-terminal region.
YP_002343091.1	NMA1805,  two component response regulator,len: 155aa; similar to the N-terminus of many regulators eg. SW:Q00934 (PILR_PSEAE) PilR typeIV fimbriae expression regulator from Pseudomonas aeruginosa (446 aa) fasta scores; E(): 3.2e-14, 41.2% identity in 153 aa overlap. Contains Pfam match to entry PF00072 response_reg,Response regulator receiver domain and Pfam match to entry PF00158 sigma54, Sigma-54 transcription factors and helix-turn-helix motif 130-151 (+3.44 SD).
YP_002343092.1	NMA1806, conserved hypothetical protein, len: 250aa; similar to many eg. SW:P72077 (YHIQ_NEIGO) hypothetical protein from Neisseria gonorrhoeae (250 aa) fasta scores; E(): 0, 95.6% identity in 250 aa overlap.
YP_002343093.1	NMA1808, metZ, O-succinylhomoserine sulfhydrolase,len: 389aa; similar to many eg. SW:P55218 (METZ_PSEAE) metZ, O-succinylhomoserine sulfhydrolase from Pseudomonas aeruginosa (403 aa) fasta scores; E(): 0, 49.9% identity in 381 aa overlap. Contains Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme.
YP_002343094.1	NMA1809, unknown, len: 253aa
YP_002343095.1	NMA1810, unknown, len: 83aa
YP_002343096.1	NMA1811, hisJ, histidine-binding periplasmic protein, len: 268aa; similar to many eg. SW:Q06758 (HISJ_NEIGO) hisJ, histidine-binding periplasmic protein from Neisseria gonorrhoeae (268 aa) fasta scores; E(): 0,96.6% identity in 268 aa overlap. Contains Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3, PS00013 Prokaryotic membrane lipoprotein lipid attachment site, and PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
YP_002343097.1	NMA1812, fumA, fumarate hydratase, len: 546aa; similar to many eg. SW:P00923 (FUMA_ECOLI) fumA, fumarate hydratase from Escherichia coli (547 aa) fasta scores; E(): 4.2e-33, 31.8% identity in 541 aa overlap.
YP_002343098.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
YP_002343099.1	NMA1814, insertion element IS1655 transposase, len: 321aa; similar to many eg. SW:P37247 (TRA4_BACFR) transposase for insertion element IS4351 from Bacteroides fragilis (326 aa) fasta scores; E(): 0, 41.9% identity in 310 aa overlap. Also N-terminal region almost identical to TR:P72086 (EMBL:U56740) transposase homolog (fragment) from Neisseria meningitidis (104 aa) fasta scores; E(): 0,99.0% identity in 104 aa overlap. Contains Pfam match to entry PF01460 Transposase_4, Transposase IS30 family and helix-turn-helix motif 22-43aa (+4.99 SD).
YP_002343100.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
YP_002343101.1	with TehA confers resistance to tellurite
YP_002343102.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_002343103.1	NMA1818, unknown, len: 143aa
YP_002343104.1	NMA1819, conserved hypothetical protein, len: 394aa; regions similar to many eg. TR:O87499 (EMBL:AF081283) hypothetical protein from Escherichia coli (304 aa) fasta scores; E(): 0, 40.5% identity in 306 aa overlap.
YP_002343105.1	NMA1820, gpxA, glutathione peroxidase, len: 177aa; previously sequenced and characterised therefore identical to SW:P52036 (GPXA_NEIME) gpxA, glutathione peroxidase from Neisseria meningitidis (177 aa) fasta scores; E(): 0,100.0% identity in 177 aa overlap. Contains Pfam match to entry PF00255 GSHPx, Glutathione peroxidases; Prosite match to PS00763 Glutathione peroxidases signature 2 and Prosite match to PS00460 Glutathione peroxidases selenocysteine active site.
YP_002343106.1	NMA1821, conserved hypothetical protein, len: 279aa; similar to SW:P44243 (YF23_HAEIN) hypothetical protein from Haemophilus influenzae (296 aa) fasta scores; E(): 0, 47.3% identity in 277 aa overlap.
YP_002343107.1	NMA1822, unknown, len: 162aa
YP_002343108.1	NMA1823, unknown, len: 207aa
YP_002343109.1	NMA1824, unknown, len: 760aa
YP_002343110.1	NMA1825, unknown, len: 188aa; weakly similar to SW:P75982 (YMFQ_ECOLI) hypothetical protein from Escherichia coli (194 aa) fasta scores; E(): 1.1e-06,26.3% identity in 190 aa overlap.
YP_002343111.1	NMA1826, unknown, len: 191aa
YP_002343112.1	NMA1827, unknown, len: 161aa
YP_002343113.1	NMA1828, unknown, len: 117aa
YP_002343114.1	NMA1829, unknown, len: 209aa; note weak similarity to SW:P31340 (VPV_BPP2) baseplate assembly protein V from Bacteriophage P2 (211 aa) fasta scores; E(): 0.0055, 27.1% identity in 214 aa overlap.
YP_002343115.1	NMA1830, unknown, len: 379aa; note weak similarity to SW:P08558 (VPP_BPMU) 43kD tail protein from Bacteriophage Mu (379 aa) fasta scores; E(): 1.9e-11,26.2% identity in 362 aa overlap.
YP_002343116.1	NMA1831, unknown, len: 455aa; weak similarity to SW:P71389 (VPN_HAEIN) cryptic Mu-phage N protein from Haemophilus influenzae (455 aa) fasta scores; E(): 0,23.3% identity in 463 aa overlap.
YP_002343117.1	NMA1832, unknown, len: 80aa
YP_002343118.1	NMA1833,  DNA-binding protein , len: 559aa; contains  helix-turn-helix motif 84-105aa (+4.43 SD).
YP_002343119.1	NMA1834, unknown, len: 82aa
YP_002343120.1	NMA1835, unknown, len: 129aa
YP_002343121.1	NMA1836, unknown, len: 65aa
YP_002343122.1	NMA1837, unknown, len: 154aa
YP_002343123.1	NMA1838,  DNA-binding protein, len: 128aa; contains helix-turn-helix motif 20-41aa (+2.60 SD).
YP_002343124.1	NMA1840, unknown, len: 124aa
YP_002343125.1	NMA1841, unknown, len: 475aa; similar to TR:P79678 (EMBL:AB000833) sheath protein from Bacteriophage Mu (495 aa) fasta scores; E(): 1.1e-10, 30.8% identity in 500 aa overlap.
YP_002343126.1	NMA1842, unknown, len: 62aa
YP_002343127.1	NMA1843, unknown, len: 222aa
YP_002343128.1	NMA1844, unknown, len: 141aa; similar to SW:P44230 (YF08_HAEIN) hypothetical protein from Haemophilus influenzae (141 aa) fasta scores; E(): 7.3e-10, 32.8% identity in 137 aa overlap.
YP_002343129.1	NMA1845, unknown, len: 157aa; contains coiled-coil region in the N-terminal half.
YP_002343130.1	NMA1847, conserved hypothetical protein, len: 300aa; similar to SW:P44230 (YF05_HAEIN) hypothetical protein from Haemophilus influenzae (308 aa) fasta scores; E(): 0, 53.6% identity in 306 aa overlap.
YP_002343131.1	NMA1848, hypothetical protein, len: 354aa; similar to SW:O05073 (VPI_HAEIN) cryptic Mu phage I protein from Haemophilus influenzae (355 aa) fasta scores; E(): 2.2e-15, 32.2% identity in 360 aa overlap.
YP_002343132.1	NMA1849, unknown, len: 165aa; similar to SW:P45255 (VPG2_HAEIN) hypothetical protein from Haemophilus influenzae (138 aa) fasta scores; E(): 5.6e-11, 38.4% identity in 164 aa overlap.
YP_002343133.1	NMA1850, unknown, len: 448aa; weakly similar to SW:P44226 (YF02_HAEIN) hypothetical protein from Haemophilus influenzae (414 aa) fasta scores; E(): 7.9e-18, 27.3% identity in 362 aa overlap.
YP_002343134.1	NMA1851, conserved hypothetical protein, len: 519aa; similar to SW:P44225 (YF01_HAEIN) hypothetical protein from Haemophilus influenzae (520 aa) fasta scores; E(): 0, 46.2% identity in 511 aa overlap.
YP_002343135.1	NMA1852, unknown, len: 539aa
YP_002343136.1	NMA1853, unknown, len: 64aa
YP_002343137.1	NMA1854,  DNA-binding protein, len: 168aa; contains helix-turn-helix motif 21-42aa (+3.63 SD).
YP_002343138.1	NMA1855, unknown, len: 71aa
YP_002343139.1	NMA1856, unknown, len: 93aa; contains hydrophilic,hydrophobic and coiled-coil regions.
YP_002343140.1	NMA1857, unknown, len: 113aa
YP_002343141.1	NMA1858, duplicated hypothetical protein, len: 72aa; identical to (but shorter than) another from Neisseria meningitidis NMA1194 fasta scores; E(): 1.8e-32, 100.0% identity in 72 aa overlap.
YP_002343142.1	NMA1859, duplicated hypothetical protein, len: 56aa; identical to another from Neisseria meningitidis NMA1193 fasta scores; E(): 6e-26, 100.0% identity in 56 aa overlap.
YP_002343143.1	NMA1860, duplicated hypothetical protein, len: 60aa; almost identical to another from Neisseria meningitidis NMA1192 fasta scores; E(): 8e-26, 98.3% identity in 60 aa overlap.
YP_002343144.1	NMA1861, duplicated hypothetical protein, len: aa; identical/almost identical to two others in Neisseria meningitidis; NMA1306 fasta scores; E(): 0, 100.0% identity in 139 aa overlap and NMA1191 fasta scores; E(): 0, 97.1% identity in 139 aa overlap.
YP_002343145.1	NMA1862, duplicated hypothetical protein, len: 78aa; identical to two others from Neisseria meningitidis; NMA1190 and NMA1305 fasta scores; E(): 2e-31, 100.0% identity in 78 aa overlap.
YP_002343146.1	NMA1863, duplicated hypothetical protein, len: 54aa; identical to two others from Neisseria meningitidis; NMA1189 and NMA1304 fasta scores; E(): 1.7e-22, 100.0% identity in 54 aa overlap.
YP_002343147.1	NMA1864, duplicated hypothetical protein, len: 54aa; almost identical to two others from Neisseria meningitidis; NMA1188 and NMA1303 fasta scores; E(): 0,96.7% identity in 181 aa overlap.
YP_002343148.1	NMA1865, unknown, len: 225aa
YP_002343149.1	NMA1866,  integral membrane protein, len: 148aa; contains  membrane-spanning hydrophobic region.
YP_002343150.1	NMA1867, unknown, len: 159aa
YP_002343151.1	NMA1868, hupB2, DNA-binding protein HU-beta, len: 91aa; strongly similar to many eg. SW:P02341 (DBHB_ECOLI) DNA-binding protein HU-beta from Escherichia coli (90 aa) fasta scores; E(): 7.1e-17, 57.8% identity in 90 aa overlap. Contains Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein.
YP_002343152.1	NMA1869, unknown, len: 66aa
YP_002343153.1	NMA1870, unknown, len: 216aa
YP_002343154.1	NMA1871, unknown, len: 203aa
YP_002343155.1	NMA1872, unknown, len: 64aa
YP_002343156.1	NMA1873, unknown, len: 151aa
YP_002343157.1	NMA1874, unknown, len: 125aa
YP_002343158.1	NMA1875, unknown, len: 104aa
YP_002343159.1	NMA1876, unknown, len: 71aa
YP_002343160.1	NMA1877,  small secreted protein, len: 54aa; contains a  non-cleavable N-terminal signal sequence.
YP_002343161.1	NMA1878, unknown, len: 50aa
YP_002343162.1	NMA1879, unknown, len: 99aa
YP_002343163.1	NMA1880, unknown, len: 80aa
YP_002343164.1	NMA1881,  DNA-binding protein, len: 304aa; similar to SW:P96343 (VPB_HAEIN) cryptic Mu-phage DNA transposition protein from Haemophilus influenzae (287 aa) fasta scores; E(): 2.4e-17, 30.6% identity in 281 aa overlap. Contains  helix-turn-helix motif 15-36aa (+6.22 SD).
YP_002343165.1	NMA1882,  transposase, len: 681aa; similar to TR:Q38013 (EMBL:X87627) transposase from Bacteriophage D3112 of Pseudomonas aeruginosa (690 aa) fasta scores; E(): 3.6e-26, 32.6% identity in 671 aa overlap. Also highly similar to TR:P72094 (EMBL:U56765) transposase homolog (fragment) from Neisseria meningitidis (90 aa) fasta scores; E(): 3.9e-29, 98.9% identity in 90 aa overlap.
YP_002343166.1	NMA1883, Ner-like DNA-binding protein, len: 87aa; similar to others eg. SW:P06020 (DBNE_BPMU) DNA-binding protein Ner from Bacteriophage Mu (74 aa) fasta scores; E(): 1.2e-10, 51.5% identity in 68 aa overlap. Contains helix-turn-helix motif 25-46aa (+4.35 SD).
YP_002343167.1	NMA1884,  regulator, len: 234aa; similar to others eg. SW:P14819 (RPC1_BPPH8) repressor protein CI from Bacteriophage phi-80 (235 aa) fasta scores; E(): 4.4e-09, 29.3% identity in 232 aa overlap.
YP_002343168.1	NMA1885, unknown, len: 52aa
YP_002343169.1	NMA1886, nor, nitric oxide reductase, len: 751aa; similar to many eg. TR:O30368 (EMBL:AF002217) nitric oxide reductase from Alcaligenes eutrophus (762 aa) fasta scores; E(): 0, 61.2% identity in 752 aa overlap. Contains Prosite match to PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature and membrane-spanning hydrophobic regions.
YP_002343170.1	NMA1887, aniA, nitrite reductase, major outer membrane copper-containing protein, len: 386aa; similar to many egs. SW:Q02219 (ANIA_NEIGO) major outer membrane protein from Neisseria gonorrhoeae (392 aa) fasta scores; E(): 0, 95.7% identity in 392 aa overlap and SW:P25006 (NIR_ACHCY) copper-containing nitrite reductase from Achromobacter cycloclastes (378 aa) fasta scores; E(): 1.2e-17, 36.4% identity in 365 aa overlap. Contains a cleavable N-terminal signal sequence and Pfam match to entry PF00394 Cu-oxidase, Multicopper oxidase and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002343171.1	NMA1888, unknown, len: 251aa
YP_002343172.1	NMA1891, conserved hypothetical protein, len: 185aa; previously sequenced therefore identical to TR:O34773 (EMBL:AF004825) hypothetical protein from Neisseria meningitidis serogroup A (185 aa) fasta scores; E(): 0, 100.0% identity in 185 aa overlap. Also similar to other hypothetical proteins eg. SW:P45244 (YDJA_HAEIN) hypothetical protein from Haemophilus influenzae (184 aa) fasta scores; E(): 0, 50.3% identity in 185 aa overlap.
YP_002343173.1	NMA1892, conserved hypothetical protein, len: 544aa; previously sequenced therefore identical to TR:O34609 (EMBL:AF004825) hypothetical protein from Neisseria meningitidis serogroup A (544 aa) fasta scores; E(): 0, 100.0% identity in 544 aa overlap. Also similar to many other hypothetical proteins eg. SW:P30845 (YJDB_ECOLI) hypothetical protein from Escherichia coli (547 aa) fasta scores; E(): 0, 44.2% identity in 547 aa overlap.
YP_002343174.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_002343175.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_002343176.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_002343177.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_002343178.1	NMA1898,  integral membrane protein, len: 464aa; N-terminal similar to that of SW:P17196 (EF1A_SULAC) elongation factor 1-alpha from Sulfolobus acidocaldarius (435 aa) fasta scores; E(): 0.25, 31.0% identity in 129 aa overlap. Contains  membrane-spanning hydrophobic region.
YP_002343179.1	NMA1899,  integral membrane protein, len: 449aa; contains  membrane-spanning hydrophobic regions.
YP_002343180.1	NMA1900,  haemolysin, len: 208aa; similar to SW:P54176 (HLY3_BACCE) hemolysin III from Bacillus cereus (219 aa) fasta scores; E(): 4e-30, 42.1% identity in 202 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343181.1	NMA1901,  sodium:alanine symporter, len: 472aa; similar to many eg. SW:P30144 (DAGA_ALTHA) Na(+)-linked D-alanine glycine permease (542 aa) fasta scores; E(): 0, 32.6% identity in 537 aa overlap. Contains Pfam match to entry PF01235 Na_Ala_symp, Sodium:alanine symporter family and Prosite match to PS00873 Sodium:alanine symporter family signature. Also contains  membrane-spanning hydrophobic regions.
YP_002343182.1	NMA1902, conserved hypothetical protein, len: 242aa; similar to many eg. SW:P24237 (YEBC_ECOLI) hypothetical protein from Escherichia coli (246 aa) fasta scores; E(): 0, 57.7% identity in 234 aa overlap.
YP_002343183.1	NMA1903,  disulphide bond formation protein, len: 199aa; similar to many eg. SW:P30018 (DSBB_ECOLI) disulphide bond formation protein B from Escherichia coli (176 aa) fasta scores; E(): 4.2e-08,28.6% identity in 161 aa overlap.
YP_002343184.1	NMA1905, AsnC-family transcriptional regulator,len: 154aa; similar to many eg. SW:P19494 (LRP_ECOLI) Lrp leucine-responsive regulatory protein from Escherichia coli (163 aa) fasta scores; E(): 3.7e-31, 56.5% identity in 147 aa overlap. Contains Pfam match to entry PF01037 ASNC_trans_reg, AsnC family.
YP_002343185.1	NMA1906, alr, alanine racemase, len: 377aa; similar to many eg. SW:P06655 (ALR1_SALTY) alr, alanine racemase from Salmonella typhimurium (359 aa) fasta scores; E(): 0,41.7% identity in 360 aa overlap. Contains Pfam match to entry PF00842 Ala_racemase, Alanine racemase and Prosite match to PS00395 Alanine racemase pyridoxal-phosphate attachment site.
YP_002343186.1	NMA1908, conserved hypothetical protein, len: 451aa; similar to TR:Q59059 (EMBL:U67606) hypothetical protein from Methanococcus jannaschii (458 aa) fasta scores; E(): 0, 62.9% identity in 453 aa overlap.
YP_002343187.1	ACT domain-containing protein
YP_002343188.1	NMA1911,  periplasmic protein, len: 245aa; contains a  cleavable N-terminal signal sequence.
YP_002343189.1	involved in methylation of ribosomal protein L3
YP_002343190.1	NMA1913, unknown, len: 197aa
YP_002343191.1	NMA1914, unknown, len: 206aa
YP_002343192.1	NMA1915,  DNA transport competence protein,len: 154 aa; region of similarity to SW:P39694 (CME1_BACSU) ComE a late competence operon protein from Bacillus subtilis (205 aa) fasta scores; E(): 9.8e-07,47.6% identity in 63 aa overlap. Previously sequenced therefore almost identical to TR:CAB44958 (EMBL:AJ242837) ComEA protein (fragment) from Neisseria meningitidis serogroup A strain Z2491 (170 aa) fasta scores; E(): 0,100.0% identity in 154 aa overlap. Contains Pfam match to entry PF00633 HHH, Helix-hairpin-helix motif and  membrane-spanning hydrophobic region. Identical to NMA2187, and almost identical to NMA0211 (98.7% identity in 154 aa overlap), and NMA0423 (98.7% identity in 154 aa overlap)
YP_002343193.1	NMA1916, unknown, len: 394aa; similar to many proposed DNA/pantothenate metabolism flavoproteins eg. SW:P24285 (DFP_ECOLI) from Escherichia coli (430 aa) fasta scores; E(): 0, 39.7% identity in 383 aa overlap.
YP_002343194.1	NMA1917, spoT, guanosine-3',5'-bis(diphosphate) 3'-pyrophophohydrolase, len: 725aa; similar to many eg. SW:P17580 (SPOT_ECOLI) spoT,guanosine-3',5'-bis(diphosphate) 3'-pyrophophohydrolase from Escherichia coli (702 aa) fasta scores; E(): 0, 45.6% identity in 697 aa overlap.
YP_002343195.1	NMA1918, rpoZ, DNA-directed RNA polymerase omega chain, len: 68aa; similar to SW:P08374 (RPOZ_ECOLI) rpoZ,DNA-directed RNA polymerase omega chain from Escherichia coli (91 aa) fasta scores; E(): 3.1e-10, 55.4% identity in 65 aa overlap.
YP_002343196.1	Essential for recycling GMP and indirectly, cGMP
YP_002343197.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_002343198.1	NMA1921, conserved hypothetical protein, len: 269aa; similar to many hypothetical proteins eg. TR:Q45494 (EMBL:AF012285) hypothetical protein from Bacillus subtilis (257 aa) fasta scores; E(): 1.7e-25, 32.6% identity in 264 aa overlap. Contains Pfam match to entry PF00592 DUF3, Domain of Unknown Function 3 and Prosite match to PS01229 Hypothetical cof family signature 2.
YP_002343199.1	NMA1923, probable protease, len: 451aa; similar to many eg. SW:P76403 (YEGQ_ECOLI)  protease from Escherichia coli (453 aa) fasta scores; E(): 0, 60.0% identity in 450 aa overlap. Contains Pfam match to entry PF01136 Peptidase_U32, Peptidase family U32 and Prosite match to PS01276 Peptidase family U32 signature.
YP_002343200.1	NMA1924, unknown, len: 158aa
YP_002343201.1	NMA1927, hemO, haem utilisation protein, len: 230aa; similar to TR:O69002 (EMBL:AF060193) PigA, iron starvation protein from Pseudomonas aeruginosa (198 aa) fasta scores; E(): 1.3e-20, 37.8% identity in 196 aa overlap. Identified as haem utilisation protein by Zhu et al, J. Bact 182, 439-447 (2000)
YP_002343202.1	NMA1928, hypothetical integral membrane protein,len: 434aa; similar to SW:P43670 (PQIA_ECOLI) paraquat-inducible protein from Escherichia coli (417 aa) fasta scores; E(): 0, 31.9% identity in 414 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343203.1	NMA1929, hypothetical integral membrane protein,len: 553aa; similar to SW:P43671 (PQIB_ECOLI) paraquat-inducible protein from Escherichia coli (546 aa) fasta scores; E(): 0, 37.0% identity in 549 aa overlap. Contains  membrane-spanning hydrophobic regions and a coiled-coil region.
YP_002343204.1	NMA1930,  lipoprotein, len: 172aa; similar to SW:P75866 (YMBA_ECOLI) hypothetical protein from Escherichia coli (182 aa) fasta scores; E(): 6.3e-08,30.1% identity in 173 aa overlap. Contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002343205.1	NMA1931, tag, DNA-3-methyladenine glycosylase I,len: 183aa; similar to many eg. SW:P05100 (3MG1_ECOLI) tag, DNA-3-methyladenine glycosylase I from Escherichia coli (187 aa) fasta scores; E(): 4.1e-13, 39.3% identity in 168 aa overlap.
YP_002343206.1	NMA1932,  lipase, len: 213aa; similar to SW:P29679 (TESA_ECOLI) acyl-CoA thioesterase I from Escherichia coli (208 aa) fasta scores; E(): 1.6e-11,34.9% identity in 172 aa overlap. Contains Pfam match to entry PF00657 Lipase_GDSL, Lipase/Acylhydrolase with GDSL-like motif.
YP_002343207.1	NMA1933,  integral membrane protein, len: 119aa; contains  membrane-spanning hydrophobic regions.
YP_002343208.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine
YP_002343209.1	NMA1936, probable cytochrome, len: 279aa; regions similar to many smaller cytochromes eg. SW:P00123 (C555_CHLLT) cytochromes c-555 from Chlorobium limicola f.sp. thiosulfatophilum (86 aa) fasta scores; E(): 9.9e-06, 41.3% identity in 80 aa overlap. Contains two Pfam matches to entry PF00034 cytochrome_c, Cytochrome c and two Prosite matches to PS00190 Cytochrome c family heme-binding site signature.
YP_002343210.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_002343211.1	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs
YP_002343212.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_002343213.1	NMA1940, unknown, len: 141aa
YP_002343214.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002343215.1	hydrolyzes diadenosine polyphosphate
YP_002343216.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002343217.1	NMA1944, ldhA, D-lactate dehydrogenase, len: 332aa; similar to many eg. SW:P52643 (LDHD_ECOLI) ldhA, D-lactate dehydrogenase from Escherichia coli (329 aa) fasta scores; E(): 0, 72.7% identity in 326 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases; Prosite match to PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3; Prosite match to PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2 and Prosite match to PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature.
YP_002343218.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_002343219.1	NMA1946, conserved hypothetical protein, len: 284aa; note  alternative downstream translational start. Similar to many eg. SW:P39408 (YJJV_ECOLI) hypothetical protein from Escherichia coli (259 aa) fasta scores; E(): 4.2e-23, 33.3% identity in 261 aa overlap. Contains Pfam match to entry PF01026 UPF0006,Uncharacterized protein family.
YP_002343220.1	NMA1947, ans, L-asparaginase, len: 329aa; similar to many eg. SW:P18840 (ASG1_ECOLI) ansA, L-asparaginase I from Escherichia coli (338 aa) fasta scores; E(): 3.6e-28,32.6% identity in 334 aa overlap. Contains Pfam match to entry PF00710 Asparaginase, Asparaginase; Prosite match to PS00144 Asparaginase / glutaminase active site signature 1 and Prosite match to PS00917 Asparaginase / glutaminase active site signature 2.
YP_002343221.1	NMA1948, DedA-family integral membrane protein,len: 261aa; similar to many eg. SW:P45280 (YG29_HAEIN) hypothetical protein from Haemophilus influenzae (212 aa) fasta scores; E(): 0, 58.5% identity in 183 aa overlap. Contains Pfam match to entry PF00597 DedA, DedA family. Also contains  membrane-spanning hydrophobic regions.
YP_002343222.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_002343223.1	NMA1950, dhpS, dihydropteroate synthase, len: 283aa; similar to many egs. SW:P26282 (DHPS_ECOLI) dhpS,dihydropteroate synthase from Escherichia coli (282 aa) fasta scores; E(): 0, 47.6% identity in 269 aa overlap and SW:Q51161 (DHPS_NEIME) dhpS, dihydropteroate synthase from Neisseria meningitidis (283 aa) fasta scores; E(): 0,91.5% identity in 283 aa overlap. Contains Pfam match to entry PF00809 DHPS, Dihydropteroate synthase and PS00793 Dihydropteroate synthase signature 2.
YP_002343224.1	NMA1951, uknown, len: 740aa; similar to SW:U11035 (ASMA_ECOLI) AsmA protein from Escherichia coli (617 aa) fasta scores; E(): 0.0047, 19.0% identity in 695 aa overlap.
YP_002343225.1	NMA1952, conserved hypothetical protein, len: 492aa; similar to many eg. SW:P26615 (YIGC_ECOLI) hypothetical protein from Escherichia coli (497 aa) fasta scores; E(): 0, 71.7% identity in 492 aa overlap.
YP_002343226.1	NMA1953, unknown, len: 171aa
YP_002343227.1	NMA1954,  integral membrane protein, len: 144aa; contains  membrane-spanning hydrophobic regions.
YP_002343228.1	NMA1955, unknown, len: 144aa
YP_002343229.1	NMA1956, insertion element IS1016 transposase, len: 222aa; similar to many eg. TR:Q48208 (EMBL:X58176) insertion sequence IS1016 from Haemophilus influenzae (164 aa) fasta scores; E(): 0, 69.6% identity in 161 aa overlap. Similar to others from Neisseria meningitidis eg. NMA2185, fasta scores; E(): 0, 94.8% identity in 211 aa overlap. Contains  helix-turn-helix motif 35-56aa (+4.71 SD).
YP_002343230.1	FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002343231.1	NMA1958, lgtF, beta-1,4-glucosyltransferase, len: 254aa; strongly similar to TR:P95373 (EMBL:U58765) lgtF,beta-1,4-glucosyltransferase from Neisseria meningitidis strain CDC8201085; NMB (252 aa) fasta scores; E(): 0,98.4% identity in 252 aa overlap. Contains Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferases.
YP_002343232.1	NMA1959, rfaK, alpha 1,2 N-acetylglucosamine transferase, len: 354aa; strongly similar to TR:Q51123 (EMBL:U58765) rfaK, alpha 1,2 N-acetylglucosamine transferase from Neisseria meningitidis strain CDC8201085; NMB (354 aa) fasta scores; E(): 0, 96.3% identity in 354 aa overlap. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1.
YP_002343233.1	NMA1960, unknown, len: 56aa
YP_002343234.1	NMA1961, probable integral membrane ion transporter, len: 445aa; similar to many proposed transporteres eg. TR:AAD20893 (EMBL:U58765) sodium/chroride ion channel from Neisseria meningitidis strain CDC8201085; NMB (445 aa) fasta scores; E(): 0,97.5% identity in 445 aa overlap. Contain two Pfam matches to entry PF00209 SNF, Sodium:neurotransmitter symporter family and  membrane-spanning hydrophobic regions.
YP_002343235.1	NMA1962, hypothetical periplasmic protein, len: 219aa; similar to many of undefined function eg. TR:O07332 (EMBL:U94899) NosX protein from Sinorhizobium meliloti (321 aa) fasta scores; E(): 7.4e-25, 50.7% identity in 150 aa overlap. Contains a  cleavable N-terminal signal sequence.
YP_002343236.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_002343237.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_002343238.1	NMA1965, GntR-family transcriptional regulator,len: 260aa; similar to many eg. SW:P06957 (PDHR_ECOLI) pyruvate dehydrogenase complex repressor from Escherichia coli (254 aa) fasta scores; E(): 2.9e-24, 36.0% identity in 247 aa overlap. Contains Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family and Prosite match to PS00043 Bacterial regulatory proteins,gntR family signature.
YP_002343239.1	NMA1966,  integral membrane protein, len: 99aa; region similar to regions from lactate permeases eg. SW:P33231 (LLDP_ECOLI) L-lactate permease from Escherichia coli (551 aa) fasta scores; E(): 4.1e-07, 48.6% identity in 70 aa overlap.
YP_002343240.1	NMA1968, mtrE,  outer membrane lipoprotein,len: 467aa; similar to many especially TR:Q51006 (EMBL:X95635) implicated in resistance to toxic hydrophobic agents in Neisseria gonorrhoeae (467 aa) fasta scores; E(): 0, 92.1% identity in 467 aa overlap. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site and coiled-coil regions.
YP_002343241.1	NMA1969, mtrD, probable drug efflux protein, len: 1067aa; strongly similar to TR:Q51073 (EMBL:U60099) MtrD protein from Neisseria gonorrhoeae (1067 aa) fasta scores; E(): 0, 96.8% identity in 1067 aa overlap and SW:P31224 (ACRB_ECOLI) acriflavin resistance protein from Escherichia coli (1049 aa) fasta scores; E(): 0, 49.4% identity in 1063 aa overlap. Contains Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family.
YP_002343242.1	NMA1970, mtrC, membrane fusion protein, len: 412aa; strongly similar to many eg. SW:P43505 (MTRC_NEIGO) mtrC,membrane fusion protein from Neisseria gonorrhoeae (412 aa) fasta scores; E(): 0, 96.4% identity in 412 aa overlap and SW:P31223 (ACRA_ECOLI) acriflavin resistance protein from Escherichia coli (397 aa) fasta scores; E(): 0, 42.4% identity in 389 aa overlap. Contains Pfam match to entry PF00529 HlyD, HlyD family secretion protein and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site and  coiled-coil region.
YP_002343243.1	NMA1971, mtrR, transcriptional regulator, len: 210aa; similar to many eg. SW:P39897 (MTRR_NEIGO) mtrR,transcriptional regulator from Neisseria gonorrhoeae (210 aa) fasta scores; E(): 0, 96.2% identity in 210 aa overlap. Contains Pfam match to entry PF00440 tetR,Bacterial regulatory proteins, tetR family; Prosite match to PS01081 Bacterial regulatory proteins, tetR family signature and  helix-turn-helix 32-53aa (+6.17 SD).
YP_002343244.1	NMA1972, unknown, len: 85aa
YP_002343245.1	NMA1973, hypothetical integral membrane protein,len: 522aa; similar to SW:P46133 (YDAH_ECOLI) hypothetical protein from Escherichia coli (510 aa) fasta scores; E(): 0, 38.5% identity in 520 aa overlap. Contains membrane-spanning hydrophobic regions.
YP_002343246.1	NMA1974, recC, exodeoxyribonuclease V, len: 1069aa; similar to SW:P07648 (EX5C_ECOLI) recC,exodeoxyribonuclease V from Escherichia coli (1122 aa) fasta scores; E(): 0, 32.3% identity in 1110 aa overlap.
YP_002343247.1	NMA1975,  integral membrane protein, len: 469aa; contains  membrane-spanning hydrophobic regions. Similar to TR:P72122 (EMBL:D28119) outer membrane protein from Pseudomonas aeruginosa (471 aa) fasta scores; E(): 0, 35.8% identity in 480 aa overlap.
YP_002343248.1	CcoO; FixO
YP_002343249.1	CcoN; FixN
YP_002343250.1	NMA1981, hypothetical protein, len: 585aa; similar to TR:Q55449 (EMBL:D64006) hypothetical protein from Synechocystis sp. (strain PCC 6803) (584 aa) fasta scores; E(): 0, 34.3% identity in 589 aa overlap.
YP_002343251.1	NMA1982, hypothetical protein, len: 155aa; similar to TR:O33514 (EMBL:U23145) hypothetical protein from Rhodobacter capsulatus (146 aa) fasta scores; E(): 5.7e-11, 34.6% identity in 130 aa overlap.
YP_002343252.1	NMA1983, exbD, biopolymer transport protein, len: 144aa; previously sequenced therefore identical to SW:P95376 (EXBD_NEIME) exbD, biopolymer transport protein from Neisseria meningitidis (144 aa) fasta scores; E(): 0,100.0% identity in 144 aa overlap. Contains membrane-spanning and coiled-coil regions.
YP_002343253.1	NMA1984, exbB, biopolymer transport protein, len: 220aa; almost identical to SW:P95375 (EXBB_NEIME) exbB,biopolymer transport protein from Neisseria meningitidis (220 aa) fasta scores; E(): 0, 98.6% identity in 220 aa overlap. Contains Pfam match to entry PF01618 MotA_ExbB and  membrane-spanning hydrophobic regions.
YP_002343254.1	NMA1985, tonB, TonB protein, len: 280aa; almost identical to SW:P95374 (TONB_NEIME) TonB protein from Neisseria meningitidis (278 aa) fasta scores; E(): 0,79.7% identity in 281 aa overlap.
YP_002343255.1	NMA1986, conserved hypothetical integral membrane protein, len: 212aa; similar to many eg. TR:O67705 (EMBL:AE000759) hypothetical protein from Aquifex aeolicus (217 aa) fasta scores; E(): 2.1e-15, 41.2% identity in 199 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343256.1	NMA1988,  integral membrane protein, len: 266aa; contains  membrane-spanning hydrophobic regions.
YP_002343257.1	NMA1989, hypothetical integral membrane protein,len: 172aa; similar to two others in this strain: NMA0784 fasta scores; E(): 0, 82.7% identity in 173 aa overlap and NMA0786 fasta scores; E(): 47.6% identity in 168 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343258.1	cofactor involved in the reduction of disulfides
YP_002343259.1	NMA1991, relA, GTP pyrophosphokinase, len: 769aa; similar to many eg. SW:P11585 (RELA_ECOLI) relA, GTP pyrophosphokinase from Escherichia coli (744 aa) fasta scores; E(): 0, 41.8% identity in 692 aa overlap.
YP_002343260.1	NMA1994, natC,  periplasmic type I secretion system protein, len: 467aa; previously sequenced in Neisseria meningitidis therefore almost identical to TR:AAD30978 (EMBL:AF121772) (467 aa) fasta scores; E(): 0,99.8% identity in 467 aa overlap. Also similar to many others eg. SW:P02930 (TOLC_ECOLI) TolC, type I secretion system protein from Escherichia coli (495 aa) fasta scores; E(): 8.8e-23, 27.6% identity in 439 aa overlap. Contains a coiled-ciol region.
YP_002343261.1	NMA1996, natD',  periplasmic type I secretion system protein, N-terminal region, len: 454aa; previously sequenced in Neisseria meningitidis therefore almost identical to N-terminal region of TR:AAD30977 (EMBL:AF121772) (475 aa) fasta scores; E(): 0, 98.9% identity in 439 aa overlap. Also similar to N-terminal region of SW:P09986 (HLY4_ECOLI) haemolysin secretion protein D from Escherichia coli (478 aa) fasta scores; E(): 0, 38.2% identity in 432 aa overlap. Note CDS is incomplete and may be able to frameshift into the downstream CDS due to the presence of a large tandem repeat between these two CDSs.
YP_002343262.1	NMA1999,  phage protein, len: 344 aa; shows weak similarity to e.g. TR:O34630 (EMBL:U83796), rstA2,Vibrio cholerae bacteriophage CTXphi protein required for replication and integration (359 aa), fasta scores; E(): 1.5e-09, 27.8% identity in 223 aa overlap. Also similar to TR:O82959 (EMBL:AB015669) ORF C7 from Burkholderia solanacearum plasmid pJTPS1 (444 aa), fasta scores; E(): 1.4e-16, 33.9% identity in 239 aa overlap. Highly similar to others from Neisseria meningitidis e.g. NMA1167, E(): 0, 100.0% identity in 344 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop)
YP_002343263.1	NMA2000, len: 114 aa; unknown, similar to others from Neisseria meningitidis e.g. NMA1168, fasta scores; E(): 0, 100.0% identity in 114 aa overlap
YP_002343264.1	NMA2001, len: 65 aa; unknown, similar to others from Neisseria meningitidis e.g. NMA1169, fasta scores; E(): 4.2e-27, 100.0% identity in 65 aa overlap
YP_002343265.1	NMA2002, len: 94 aa; unknown, similar to others from Neisseria meningitidis e.g. NMA1170, fasta scores; E(): 0, 100.0% identity in 94 aa overlap
YP_002343266.1	NMA2003, len: 92 aa; unknown, similar to others from Neisseria meningitidis e.g. NMA2003, fasta scores; E(): 0, 100.0% identity in 92 aa overlap
YP_002343267.1	NMA2004, len: 105 aa; similar to others from Neisseria meningitidis e.g. TR:O87782 (EMBL:AJ010115) Neisseria meningitidis strain B:15:P1.16 hypothetical protein (fragment) (148 aa), fasta scores; E(): 1.2e-24,57.3% identity in 110 aa overlap. Also similar to NMA1172,fasta scores; E(): 4e-25 54.8% identity in 104 aa overlap. Lies within a region of unusually low GC content.
YP_002343268.1	NMA2005, probable cell-surface protein, len: 146 aa; highly similar to the N-terminus of TR:O87783 (EMBL:AJ010115), tspB, Neisseria meningitidis strain B:15:P1.16 T-cell and B-cell antigen (partial CDS) (504 aa), fasta scores; E(): 7.3e-25, 84.1% identity in 88 aa overlap. Similar to others from Neisseria meningitidis,e.g. NMA0776, fasta scores; E(): 1.9e-20, 61.5% identity in 96 aa overlap, and NMA1797 fasta scores; E(): 7.8e-23,68.0% identity in 97 aa overlap, (both tspB genes) and NMA1173 fasta scores; E(): 2.9e-30, 66.2% identity in 133 aa overlap (another  cell-surface protein). N-terminal half has low GC content. Contains a probable N-terminal signal sequence
YP_002343269.1	NMA2006, conserved hypothetical protein, len: 119aa; similar to many eg. TR:O67700 (EMBL:AE000759) hypothetical protein from Aquifex aeolicus (117 aa) fasta scores; E(): 3.6e-15, 42.0% identity in 112 aa overlap.
YP_002343270.1	NMA2007, unknown, len: 214aa
YP_002343271.1	NMA2008, conserved hypothetical protein, len: 178aa; similar to many eg. TR:O67698 (EMBL:AE000759) hypothetical protein from Aquifex aeolicus (186 aa) fasta scores; E(): 1.2e-16, 34.6% identity in 179 aa overlap.
YP_002343272.1	NMA2009, unknown, len: 365aa
YP_002343273.1	NMA2010, hypothetical protein, len: 463aa; weakly similar to TR:Q56292 (EMBL:L18975) hypothetical protein from Thiobacillus ferrooxidans (318 aa) fasta scores; E(): 0.86, 24.6% identity in 349 aa overlap.
YP_002343274.1	NMA2011, conserved hypothetical protein, len: 264aa; highly similar to SW:P45249 (BIOC_HAEIN)  biotin synthesis protein from Haemophilus influenzae (260 aa) fasta scores; E(): 0, 92.2% identity in 255 aa overlap. Also weakly similar to SW:P12999 (BIOC_ECOLI) biotin synthesis protein from Escherichia coli (251 aa) fasta scores; E(): 1.8e-07, 25.9% identity in 259 aa overlap.
YP_002343275.1	NMA2012, conserved hypothetical protein, len: 215aa; highly similar to SW:P44251 (YF52_HAEIN) hypothetical protein from Haemophilus influenzae (215 aa) fasta scores; E(): 0, 86.0% identity in 215 aa overlap.
YP_002343276.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
YP_002343277.1	NMA2014, unknown, len: 358aa
YP_002343278.1	NMA2015,  integral membrane transport protein, len: 488aa; similar to many eg. SW:Q41364 (SOT1_SPIOL) 2-oxoglutarate/malate translocator from Spinacia oleracea (Spinach) (569 aa) fasta scores; E(): 0,44.2% identity in 480 aa overlap. Contains Pfam match to entry PF00939 Na_sulph_symp, Sodium:sulfate symporter transmembrane region and several  membrane-spanning hydrophobic regions.
YP_002343279.1	catalyzes the formation of putrescine from agmatine
YP_002343280.1	catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis
YP_002343281.1	NMA2018, hypothetical periplasmic protein, len: 94aa; cContains a  cleavable N-terminal signal sequence.
YP_002343282.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_002343283.1	NMA2020,  integral membrane protein, len: 245aa; similar to TR:Q9Z846 (EMBL:AE001635) hypothetical protein from Chlamydia pneumoniae (223 aa) fasta scores; E(): 1.5e-21, 31.8% identity in 220 aa overlap. Contains membrane-spanning hydrophobic regions.
YP_002343284.1	NMA2021,  phopholipase, len: 409aa; similar to, but longer than, many eg. SW:P00631 (PA1_ECOLI) phopholipase A1 from Escherichia coli (289 aa) fasta scores; E(): 1.3e-25, 37.5% identity in 256 aa overlap. Note alternative translational start sites downstream.
YP_002343285.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_002343286.1	NMA2023,  polyamine permease substrate-binding protein, len: 407aa; similar to many eg. SW:P31133 (POTF_ECOLI) putrescine-binding periplasmic protein (370 aa) fasta scores; E(): 0, 38.9% identity in 352 aa overlap. Also similar to NMA0831 (fasta scores; E(): 0, 54.8% identity in 396 aa overlap) and NMA2023 fasta scores; (E(): 0, 55.2% identity in 377 aa overlap) from Neisseria meningitidis. Contains a  cleavable N-terminal signal sequence.
YP_002343287.1	NMA2024, tbpA, transferrin-binding protein A, len: 910aa; previously sequenced therefore identical to TR:Q53348 (EMBL:AF058689). Contains Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region and Prosite match to PS01156 TonB-dependent receptor proteins signature 2.
YP_002343288.1	NMA2025, tbpB, transferrin-binding protein B, len: 698aa; previously sequenced therefore identical to TR:O68937 (EMBL:AF058689). Contains Pfam match to entry PF01298 Lipoprotein_5, Transferrin binding protein and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
YP_002343289.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_002343290.1	NMA2027, conserved hypothetical protein, len: 153aa; similar to many eg. SW:P31805 (YJEE_ECOLI) hypothetical protein from Escherichia coli (153 aa) fasta scores; E(): 9.3e-26, 48.9% identity in 137 aa overlap.
YP_002343291.1	NMA2028, amiC, N-acetylmuramoyl-L-alanine amidase,len: 416aa; similar to many eg. SW:Q46929 (AMIC_ECOLI) amiC, N-acetylmuramoyl-L-alanine amidase from Escherichia coli (417 aa) fasta scores; E(): 0, 51.1% identity in 425 aa overlap. Contains Pfam match to entry PF01520 Amidase_3.
YP_002343292.1	NMA2029, unknown, len: 290aa
YP_002343293.1	NMA2030, conserved hypothetical protein, len: 380aa; similar to the N-terminal half of many hypothetical proteins eg. SW:P75864 (YCBY_ECOLI) hypothetical protein from Escherichia coli (702 aa) fasta scores; E(): 0, 37.9% identity in 372 aa overlap. Also similar and equal in length to many others eg. SW:Q55156 (Y064_SYNY3) hypothetical protein from Synechocystis sp. (strain PCC 6803) (384 aa) fasta scores; E(): 0, 34.8% identity in 374 aa overlap. Contains Pfam match to entry PF01170 UPF0020,Uncharacterized protein family UPF0020 and Prosite match to PS01261 Uncharacterized protein family UPF0020 signature.
YP_002343294.1	NMA2031,  secreted protein, len: 140aa; contains a cleavable N-terminal signal sequence.
YP_002343295.1	NMA2032, MutT-related protein, len: 269aa; similar to but larger than many MutT homlogs eg. SW:P44932 (MUTT_HAEIN) MutT protein from Haemophilus influenzae (136 aa) fasta scores; E(): 3.5e-13, 40.6% identity in 128 aa overlap. Contains Pfam match to entry PF00293 mutT,Bacterial mutT protein and Prosite match to PS00893 mutT domain signature.
YP_002343296.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_002343297.1	NMA2035, conserved hypothetical protein, len: 255aa; weakly similar to many eg. TR:O66527 (EMBL:AE000675) hypothetical protein from Aquifex aeolicus (272 aa) fasta scores; E(): 0.0001, 24.6% identity in 256 aa overlap. Lies in a region of unusually low GC content.
YP_002343298.1	NMA2036, unknown, len: 259aa; Lies in a region of unusually low GC content.
YP_002343299.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
YP_002343300.1	NMA2038, recO, DNA repair protein (recombination protein o), len: aa; similar to many eg. TR:Q9ZHY2 (EMBL:AF047375) RecO protein from Neisseria gonorrhoeae (247 aa) fasta scores; E(): 0, 80.7% identity in 244 aa overlap.
YP_002343301.1	NMA2039, pheA, chorismate mutase, len: 375aa; similar to many egs. TR:Q9ZHY3 (EMBL:AF047375) PheA from Neisseria gonorrhoeae (375 aa) fasta scores; E(): 0, 98.7% identity in 375 aa overlap and SW:P27603 (PHEA_PSEST) chorismate mutase from Pseudomonas stutzeri (365 aa) fasta scores; E(): 0, 50.4% identity in 357 aa overlap. Contains Pfam match to entry PF00800 PDT, Prephenate dehydratase and Prosite match to PS00857 Prephenate dehydratase signature 1.
YP_002343302.1	NMA2040,  integral membrane efflux protein,len: 410aa; similar to many eg. SW:P28246 (BCR_ECOLI) bicyclomycin resistance protein from Escherichia coli (396 aa) fasta scores; E(): 0, 29.0% identity in 386 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343303.1	NMA2041, conserved hypothetical protein, len: 284aa; similar to many hypothetical protein, some of which occur as two seperate CDSs ie. N-terminal region similar to SW:Q57147 (Y976_HAEIN) hypothetical protein from Haemophilus influenzae (128 aa) fasta scores; E(): 1.1e-18, 53.5% identity in 114 aa overlap; C-terminal region similar to SW:O86230 (Y97X_HAEIN) hypothetical protein from Haemophilus influenzae (170 aa) fasta scores; E(): 8.9e-27, 48.1% identity in 156 aa overlap. Contains a Pfam match to entry PF00892 DUF6, Integral membrane protein in both the N and C-terminal regions.
YP_002343304.1	NMA2044, conserved hypothetical protein, len: 270aa; similar to SW:P55175 (Y601_SYNY3) hypothetical protein from Synechocystis sp. (strain PCC 6803) (272 aa) fasta scores; E(): 0, 40.4% identity in 275 aa overlap.
YP_002343305.1	NMA2045,  oxidoreductase, len: 290aa; similar to many eg. SW:P20692 (TYRA_BACSU) prephenate dehydrogenase from Bacillus subtilis (372 aa) fasta scores; E(): 2.8e-30, 39.4% identity in 284 aa overlap.
YP_002343306.1	NMA2046, hypothetical integral membrane protein,len: 400aa; similar to TR:P95556 (EMBL:Z73914) hypothetical protein from Pseudomonas stutzeri (396 aa) fasta scores; E(): 0, 35.0% identity in 391 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343307.1	NMA2047, hypothetical protein, len: 122aa; weakly similar to SW:P71932 (YQ03_MYCTU) hypothetical protein from Mycobacterium tuberculosis (161 aa) fasta scores; E(): 0.017, 32.5% identity in 117 aa overlap.
YP_002343308.1	NMA2048, conserved hypothetical protein, len: 147aa; similar to many eg. SW:P21498 (YJEB_ECOLI) hypothetical protein from Escherichia coli (141 aa) fasta scores; E(): 5.9e-23, 47.9% identity in 140 aa overlap.
YP_002343309.1	NMA2049, conserved hypothetical protein, len: 206aa; similar to many eg. SW:P45847 (YCIO_ECOLI) hypothetical protein from Escherichia coli (206 aa) fasta scores; E(): 0, 62.9% identity in 205 aa overlap. Contains Pfam match to entry PF01300 Sua5_yciO_yrdC, SUA5/yciO/yrdC family and Prosite match to PS01147 SUA5/yciO/yrdC family signature.
YP_002343310.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_002343311.1	NMA2051, conserved hypothetical protein, len: 389aa; similar to SW:O07931 (YRAM_BACSU) hypothetical protein from Bacillus subtilis (367 aa) fasta scores; E(): 0, 37.1% identity in 385 aa overlap.
YP_002343312.1	Catalyzes the conversion of citrate to isocitrate
YP_002343313.1	NMA2053, conserved hypothetical integral membrane protein, len: 262aa; similar to many eg. SW:P29942 (YCB9_PSEDE) hypothetical protein from Pseudomonas denitrificans (261 aa) fasta scores; E(): 0, 48.4% identity in 256 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343314.1	catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity
YP_002343315.1	catalyzes the formation of pyruvate and succinate from 2-methylisocitrate
YP_002343316.1	NMA2056, conserved hypothetical protein, len: 436aa; similar to many eg. SW:Q57772 (Y326_METJA) hypothetical protein from Methanococcus jannaschii (436 aa) fasta scores; E(): 0, 50.5% identity in 430 aa overlap. Contains Pfam match to entry PF00860 xan_ur_permease, Xanthine/uracil permeases family.
YP_002343317.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_002343318.1	NMA2058, ftsA, cell division protein, len: 414aa; strongly similar to many eg. SW:P06137 (FTSA_ECOLI) ftsA,cell division protein from Escherichia coli (420 aa) fasta scores; E(): 0, 41.9% identity in 420 aa overlap.
YP_002343319.1	NMA2059, ftsQ, cell division protein, len: 242aa; similar to many eg. SW:P06136 (FTSQ_ECOLI) ftsQ, cell division protein from Escherichia coli (276 aa) fasta scores; E(): 9.1e-26, 34.7% identity in 239 aa overlap.
YP_002343320.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002343321.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_002343322.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_002343323.1	NMA2063, ftsW, cell division protein, len: 435aa; similar to many eg. SW:P16457 (FTSW_ECOLI) ftsW, cell division protein from Escherichia coli (414 aa) fasta scores; E(): 0, 39.3% identity in 394 aa overlap. Contains Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein and Prosite match to PS00428 Cell cycle proteins ftsW / rodA / spoVE signature.
YP_002343324.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_002343325.1	NMA2065,  periplasmic protein, len: 90aa; contains a  cleavable N-terminal signal sequence.
YP_002343326.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_002343327.1	NMA2067,  periplasmic protein, len: 60aa; contains a  cleavable N-terminal signal sequence.
YP_002343328.1	NMA2068, murF, UDP-MurNAc-pentapeptide synthetase,len: 452aa; similar to many eg. SW:P11880 (MURF_ECOLI) murF, UDP-MurNAc-pentapeptide synthetase from Escherichia coli (452 aa) fasta scores; E(): 0, 41.0% identity in 456 aa overlap. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family.
YP_002343329.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_002343330.1	NMA2072, penA, penicillin-binding protein 2, len: 581aa; highly similar to many from Neisseria. Identical to SW:P11882 (PBP2_NEIME) from Neisseria meningitidis (581 aa). Contains Pfam match to entry PF00905 Transpeptidase,Penicillin binding protein transpeptidase domain.
YP_002343331.1	NMA2073,  small periplasmic protein, len: 89aa; contains a  cleavable N-terminal signal sequence.
YP_002343332.1	NMA2074, conserved hypothetical protein, len: aa; similar to many eg. SW:P18595 (YABC_ECOLI) hypothetical protein from Escherichia coli (313 aa) fasta scores; E(): 0, 53.3% identity in 315 aa overlap.
YP_002343333.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_002343334.1	NMA2076, conserved hypothetical protein, len: 405aa; similar to many eg. TR:Q57456 (EMBL:D64000) hypothetical protein from Synechocystis sp. (strain PCC 6803) (416 aa) fasta scores; E(): 0, 33.2% identity in 371 aa overlap. Note  alternative downstream start codons.
YP_002343335.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell
YP_002343336.1	NMA2078,  thiol:disulphide interchange protein, len: 214aa; weakly similar to many eg. SW:P95460 (DSBA_PSEAE) DsbA, proposed thiol:disulphide interchange protein from Pseudomonas aeruginosa (210 aa) fasta scores; E(): 2.1e-16, 33.5% identity in 203 aa overlap. Contains Pfam match to entry PF01323 DSBA, DSBA oxidoreductase and Prosite match to PS00194 Thioredoxin family active site. Contains a  cleavable N-terminal signal sequence.
YP_002343337.1	NMA2079, hypothetical lysine-rich membrane protein,len: 289aa; contains a  non-cleavable N-terminal signal sequence.
YP_002343338.1	NMA2080,  chelatase, len: 498aa; similar to many eg. SW:P45049 (YIFB_HAEIN) hypothetical protein from Haemophilus influenzae (509 aa) fasta scores; E(): 0,50.0% identity in 500 aa overlap. Contains Pfam match to entry PF01078 Mg_chelatase, Magnesium chelatase, subunit ChlI.
YP_002343339.1	NMA2081, hypothetical protein, len: 117aa; N-terminal region similar to SW:Q46868 (YQIC_ECOLI) hypothetical protein from Escherichia coli (116 aa) fasta scores; E(): 2.7e-06, 40.7% identity in 81 aa overlap. Contains  coiled-coil region.
YP_002343340.1	NMA2083, putP, sodium/proline symporter, len: 508aa; strongly similar to many eg. SW:P07117 (PUTP_ECOLI) putP, sodium/proline symporter from Escherichia coli (502 aa) fasta scores; E(): 0, 64.1% identity in 504 aa overlap. Contains Pfam match to entry PF00474 SSF,Sodium:solute symporter family, Prosite match to PS00456 Sodium:solute symporter family signature 1 and Prosite match to PS00457 Sodium:solute symporter family signature 2.
YP_002343341.1	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain
YP_002343342.1	NMA2086, xthA, exodeoxyribonuclease III, len: 256aa; similar to many eg. SW:P09030 (EX3_ECOLI) xthA,exodeoxyribonuclease III from Escherichia coli (268 aa) fasta scores; E(): 1.6e-17, 36.5% identity in 266 aa overlap. Contains Pfam match to entry PF01260 AP_endonucleas1, AP endonuclease family 1 and Prosite match to PS00726 AP endonucleases family 1 signature 1.
YP_002343343.1	NMA2088, nadC, nicotinate-nucleotide pyrophosphorylase, len: 293aa; similar to many eg. SW:O06594 (NADC_MYCTU) nadC, nicotinate-nucleotide pyrophosphorylase from Mycobacterium tuberculosis (285 aa) fasta scores; E(): 0, 45.5% identity in 277 aa overlap.
YP_002343344.1	NMA2089,  cytoplasmic membrane protein,len: 312aa; contains a  non-cleavable N-terminal signal sequence. Region around 200-300aa similar to region in several hypothetical proteins eg. TR:P74291 (EMBL:D90913) from Synechocystis sp. strain PCC6803 (261 aa) fasta scores; E(): 1.7e-05, 27.1% identity in 129 aa overlap.
YP_002343345.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_002343346.1	NMA2091,  integral membrane drug resistance protein, len: 111aa; strongly similar to many drug resistance proteins eg. SW:P14319 (EBR_STAAU) ethidium bromide resistance protein from Staphylococcus aureus (107 aa) fasta scores; E(): 2.5e-17, 53.5% identity in 101 aa overlap. Contains Pfam match to entry PF00893 DUF7,Integral membrane protein.
YP_002343347.1	NMA2092, nadB, L-aspartate oxidase, len: 502aa; similar to many eg. SW:P38032 (NADB_BACSU) nadB,L-aspartate oxidase from Bacillus subtilis (531 aa) fasta scores; E(): 0, 37.3% identity in 507 aa overlap. Contains Pfam match to entry PF00890 FAD_binding_2, FAD binding domain.
YP_002343348.1	NMA2093, pgm2, beta-phosphoglucomutase, len: 221aa; similar to many eg. SW:P71447 (PGMB_LACLA) pgmB,beta-phosphoglucomutase from Lactococcus lactis (subsp. lactis) (221 aa) fasta scores; E(): 0, 68.2% identity in 220 aa overlap. Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase. Highly similar to the neighbouring gene NMA2097 (fasta scores; E(): 0, 95.9% identity in 221 aa overlap) indicating a  duplication event.
YP_002343349.1	NMA2095,  integral membrane efflux protein,len: 350aa; similar to SW:P74311 (Y944_SYNY3) hypothetical protein from Synechocystis sp. (strain PCC 6803) (383 aa) fasta scores; E(): 0, 44.4% identity in 342 aa overlap. Weakly similar to SW:Q06598 (ACR3_YEAST) arsenical resistance protein from Saccharomyces cerevisiae (Baker's yeast) (404 aa) fasta scores; E(): 2.2e-13, 26.4% identity in 382 aa overlap. Lies in a region of unusually low GC content and may therefore be 'recently acquired'. Contains membrane-spanning hydrophobic regions.
YP_002343350.1	NMA2097, pgm1, beta-phosphoglucomutase, len: 221aa; similar to many eg. SW:P71447 (PGMB_LACLA) pgmB,beta-phosphoglucomutase from Lactococcus lactis (subsp. lactis) (221 aa) fasta scores; E(): 0, 66.4% identity in 220 aa overlap. Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase. Highly similar to the neighbouring gene NMA2093 (fasta scores; E(): 0, 95.9% identity in 221 aa overlap) indicating a  duplication event.
YP_002343351.1	NMA2098, mapA,  maltose phosphorylase, len: 752aa; similar to TR:O87772 (EMBL:AJ224340) mapA,  maltose phosphorylase from Lactobacillus sanfrancisco (753 aa) fasta scores; E(): 0, 59.9% identity in 749 aa overlap. C-terminus highly similar to the neighbouring gene NMA2094 (fasta scores; E(): 3.5e-32, 98.8% identity in 86 aa overlap) indicating a  duplication event.
YP_002343352.1	NMA2099, galM, aldose 1-epimerase (mutarotase),len: 336aa; similar to many eg. SW:P21955 (GALM_STRTR) galM, aldose 1-epimerase (mutarotase) from Streptococcus thermophilus (348 aa) fasta scores; E(): 4e-22, 35.3% identity in 340 aa overlap. Contains Pfam match to entry PF01263 Aldose_epim, Aldose 1-epimerase.
YP_002343353.1	NMA2100,  integral membrane transport protein, len: 451aa; similar to many eg. SW:Q03411 (STP_SPIOL) sucrose transport protein from Spinacia oleracea (Spinach) (525 aa) fasta scores; E(): 6.5e-07,24.5% identity in 493 aa overlap.
YP_002343354.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_002343355.1	NMA2102, pgpA, phosphatidylglycerophosphatase A,inner membrane, len: 161aa; similar to SW:P18200 (PGPA_ECOLI) pgpA, phosphatidylglycerophosphatase A from Escherichia coli (172 aa) fasta scores; E(): 6.7e-24,42.1% identity in 145 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343356.1	catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP
YP_002343357.1	NMA2105, rmpM, outer membrane protein class 4, len: 242aa; strongly similar to SW:P38367 (OMP4_NEIME) rmpM,outer membrane protein class 4 from Neisseria meningitidis (240 aa) fasta scores; E(): 0, 99.2% identity in 242 aa overlap. Contains Pfam match to entry PF00691 OmpA, OmpA family and Prosite match to PS01068 OmpA-like domain.
YP_002343358.1	NMA2106, transcriptional regulator, len: 316aa; similar to many eg. SW:P06613 (CYSB_ECOLI) cysB, cys regulon transcriptional activator (324 aa) fasta scores; E(): 0, 50.6% identity in 316 aa overlap. Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family and Prosite match to PS00044 Bacterial regulatory proteins, lysR family signature.
YP_002343359.1	NMA2107,  anaerobic transcriptional regulatory protein, len: 244aa; similar to many eg. SW:P23926 (ANR_PSEAE) transcriptional activator protein Anr from seudomonas aeruginosa (244 aa) fasta scores; E(): 0, 47.8% identity in 226 aa overlap. Contains Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain and Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family. Contains  helix-turn-helix motif 190-211aa (+3.65 SD).
YP_002343360.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002343361.1	NMA2109,  phosphate permease, len: 524aa; similar to TR:Q50684 (EMBL:Z77163)  phosphate permease from Mycobacterium tuberculosis (552 aa) fasta scores; E(): 0, 58.3% identity in 511 aa overlap. Contains Pfam match to entry PF01384 PHO4, Phosphate transporter family.
YP_002343362.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
YP_002343363.1	NMA2112, mafA2, adhesin, len: 313aa; similar to TR:AAD31038 (EMBL:AF142582) MafA adhesin from Neisseria gonorrhoeae (320 aa) fasta scores; E(): 0, 62.4% identity in 314 aa overlap. Also similar to NMA0325 fasta scores; E(): 0, 62.4% identity in 314 aa overlap.
YP_002343364.1	NMA2113, mafB2, adhesin, len: 498aa; similar to TR:AAD31039 (EMBL:AF142582) adhesin MafB from Neisseria gonorrhoeae (509 aa) fasta scores; E(): 0, 30.7% identity in 514 aa overlap. Also similar to NMA0853 fasta scores; E(): 0, 38.6% identity in 412 aa overlap and NMA0324 fasta scores; E(): 0, 31.6% identity in 503 aa overlap.
YP_002343365.1	NMA2114, hypothetical protein, len: 2114aa; lies within a region of unusually low GC content.
YP_002343366.1	NMA2115, hypothetical protein, len: 224aa; lies within a region of unusually low GC content.
YP_002343367.1	NMA2116, hypothetical protein, len: 93aa; lies within a region of unusually low GC content.
YP_002343368.1	NMA2117, hypothetical protein, len: 161aa; lies within a region of unusually low GC content.
YP_002343369.1	NMA2118, hypothetical protein, len: 125aa; lies within a region of unusually low GC content.
YP_002343370.1	NMA2120, hypothetical protein, len: 133aa; lies within a region of unusually low GC content.
YP_002343371.1	NMA2121, hypothetical protein, len: 171aa; lies within a region of unusually low GC content.
YP_002343372.1	NMA2122, hypothetical protein, len: 374aa
YP_002343373.1	NMA2123, frpC',  partial CDS, hypothetical protein, len: 91aa; highly similar to the N-terminus of SW:P55127 (FRPC_NEIME) iron-regulated protein FrpC from Neisseria meningitidis strain FAM20 (1829 aa) fasta scores; E(): 3.4e-29, 96.2% identity in 78 aa overlap.
YP_002343374.1	NMA2124,  outer membrane hypothetical protein, len: 255aa; strongly similar to TR:Q08840 (EMBL:L06299) hypothetical protein from Neisseria meningitidis strain FAM20 (271 aa) fasta scores; E(): 0,90.0% identity in 271 aa overlap.
YP_002343375.1	NMA2126, hypothetical protein, len: 91aa; similar to TR:P95364 (EMBL:U82701) hypothetical protein from Neisseria gonorrhoeae (91 aa) fasta scores; E(): 0, 95.6% identity in 91 aa overlap.
YP_002343376.1	NMA2127,  integral membrane signal transducer protein, len: 427aa; similar to many eg. TR:P95363 (EMBL:U82701) hypothetical protein from Neisseria gonorrhoeae (427 aa) fasta scores; E(): 0, 97.9% identity in 427 aa overlap and SW:P36670 (AMPG_ECOLI) AmpG, signal transducer protein from Escherichia coli (491 aa) fasta scores; E(): 0, 40.2% identity in 398 aa overlap. Contains membrane-spanning hydrophobic regions.
YP_002343377.1	NMA2128, glnA, glutamine synthetase, len: 472aa; strongly similar to many eg. TR:P95395 (EMBL:U82856) glnA,glutamine synthetase from Neisseria meningitidis strain M470 (468 aa) fasta scores; E(): 0, 99.6% identity in 468 aa overlap. Contains Pfam match to entry PF00120 gln-synt,Glutamine synthetase; Prosite match to PS00182 Glutamine synthetase class-I adenylation site; Prosite match to PS00181 Glutamine synthetase  ATP-binding region signature and Prosite match to PS00180 Glutamine synthetase signature 1.
YP_002343378.1	NMA2129, aroE, shikimate dehydrogenase, len: 271aa; strongly similar to many eg. TR:P95387 (EMBL:U82840) aroE,shikimate dehydrogenase from Neisseria meningitidis strain 44/76 (269 aa) fasta scores; E(): 0, 98.9% identity in 269 aa overlap. Contains Pfam match to entry PF01488 Shikimate_DH, Shikimate / quinate 5-dehydrogenase.
YP_002343379.1	glycosyltransferase; polymerizes glycan strands in the peptidoglycan
YP_002343380.1	NMA2131,  ABC transporter ATP-binding protein, len: 254aa; similar to many of undefined function eg. TR:O30650 (EMBL:AF013987)  ABC transporter ATP-binding protein from Vibrio cholerae (241 aa) fasta scores; E(): 0, 61.5% identity in 239 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter; Prosite match to PS00211 ABC transporters family signature and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002343381.1	NMA2132,  outer membrane hypothetical protein, len: 176aa; similar to SW:P45074 (YHBN_HAEIN) hypothetical protein from Haemophilus influenzae fasta scores; E(): 4.3e-14, 39.5% identity in 172 aa overlap.
YP_002343382.1	NMA2133,  periplasmic hypothetical protein,len: 193aa
YP_002343383.1	NMA2134, conserved hypothetical protein, len: 178aa; similar to many eg. SW:P45396 (YRBI_ECOLI) hypothetical protein from Escherichia coli (188 aa) fasta scores; E(): 1.5e-28, 46.0% identity in 174 aa overlap.
YP_002343384.1	NMA2135, conserved hypothetical protein, len: 324aa; similar to many eg. SW:P45395 (YRBH_ECOLI) hypothetical protein from Escherichia coli (328 aa) fasta scores; E(): 0, 56.2% identity in 313 aa overlap. Contains two Pfam matches to entry PF00571 CBS, CBS domain and Pfam match to entry PF01380 SIS, SIS domain.
YP_002343385.1	catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate
YP_002343386.1	NMA2137, hypothetical protein, len: 96aa; lies within a region of unusually low GC content.
YP_002343387.1	this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu
YP_002343388.1	NMA2139, conserved hypothetical protein, len: 336aa; similar to many eg. SW:P32695 (YJBN_ECOLI) hypothetical protein from Escherichia coli (330 aa) fasta scores; E(): 0, 54.4% identity in 318 aa overlap. Contains Pfam match to entry PF01207 UPF0034, Uncharacterized protein family UPF0034 and Prosite match to PS01136 Uncharacterized protein family UPF0034 signature.
YP_002343389.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine
YP_002343390.1	NMA2141, hypothetical protein, len: 239aa
YP_002343391.1	NMA2142,  periplasmic hypothetical protein,len: 288aa; similar to SW:P37566 (YACD_BACSU) hypothetical protein from Bacillus subtilis (297 aa) fasta scores; E(): 7.7e-08, 22.6% identity in 292 aa overlap. Contains a cleavable N-terminal signal sequence.
YP_002343392.1	NMA2143, conserved hypothetical protein, len: 92aa; similar to many eg. SW:P29943 (YCB1_PSEDE) hypothetical protein from Pseudomonas denitrificans (93 aa) fasta scores; E(): 4.2e-07, 37.8% identity in 90 aa overlap.
YP_002343393.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
YP_002343394.1	Involved in cell division; probably involved in intracellular septation
YP_002343395.1	NMA2146, tspA, Neisseria-specific antigen protein,len: 880aa; identical to TR:O86394 (EMBL:AJ010113) tspA,Neisseria-specific antigen protein from Neisseria meningitidis strain B:15:P1.16. (880 aa).
YP_002343396.1	NMA2147, gloA, lactoylglutathione lyase, len: 138aa; identical to SW:O33393 (LGUL_NEIME) gloA,lactoylglutathione lyase from Neisseria meningitidis strain B:15:P1.16 (138 aa). Similar to SW:Q60003 (LGUL_SALTY) gloA, lactoylglutathione lyase from Salmonella typhimurium (135 aa) fasta scores; E(): 0,67.7% identity in 127 aa overlap. Contains Pfam match to entry PF00903 Glyoxalase, Glyoxalase and Prosite match to PS00934 Glyoxalase I signature 1.
YP_002343397.1	NMA2148,  periplasmic hypothetical protein,len: 389aa; similar to SW:P45576 (YCIM_ECOLI) hypothetical protein from Escherichia coli (389 aa) fasta scores; E(): 1.5e-32, 29.2% identity in 387 aa overlap. Contains a cleavable N-terminal signal sequence.
YP_002343398.1	NMA2149,  inner membrane hypothetical protein, len: 104aa; weakly similar to TR:O32045 (EMBL:Z99118) hypothetical protein from Bacillus subtilis (107 aa) fasta scores; E(): 0.18, 35.0% identity in 80 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343399.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_002343400.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_002343401.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
YP_002343402.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_002343403.1	NMA2155, pilG, pilus-assembly protein, len: 410aa; strongly similar to many eg. TR:Q57076 (EMBL:U32588) pilG,pilus-assembly protein from Neisseria gonorrhoeae (410 aa) fasta scores; E(): 0, 99.3% identity in 410 aa overlap. Contains Pfam match to entry PF00482 GSPII_F, Bacterial type II secretion system protein F domain and Prosite match to PS00874 Bacterial type II secretion system protein F signature. Also contains membrane-spanning hydrophobic regions.
YP_002343404.1	NMA2156, pilD, type IV prepilin leader peptidase,len: 286aa; strongly similar to many eg. SW:P33566 (LEP3_NEIGO) pilD, type IV prepilin peptidase from Neisseria gonorrhoeae (286 aa) fasta scores; E(): 0, 96.1% identity in 285 aa overlap. Contains Pfam match to entry PF01478 Peptidase_C20, Type III leader peptidase family and  membrane-spanning hydrophobic regions.
YP_002343405.1	NMA2157, conserved hypothetical protein, len: 210aa; similar to many eg. SW:P36679 (YACE_ECOLI) hypothetical protein from Escherichia coli (206 aa) fasta scores; E(): 2.1e-19, 37.9% identity in 195 aa overlap. Contains Pfam match to entry PF01121 UPF0038,Uncharacterized protein family UPF0038 and Prosite match to PS01294 Uncharacterized protein family UPF0038 signature.
YP_002343406.1	NMA2158, conserved hypothetical protein, len: 69aa; similar to others eg. TR:O69083 (EMBL:AF062531) hypothetical protein from Pseudomonas putida GB-1 (66 aa) fasta scores; E(): 1.4e-10, 50.8% identity in 61 aa overlap.
YP_002343407.1	NMA2159, pilF, type IV pilus assembly protein, len: 558aa; strongly similar to many eg. SW:P37094 (PILF_NEIGO) pilF, type IV pilus assembly protein from Neisseria gonorrhoeae (558 aa) fasta scores; E(): 0, 99.3% identity in 558 aa overlap. Contains Pfam match to entry PF00437 GSPII_E, Bacterial type II secretion system protein; Prosite match to PS00662 Bacterial type II secretion system protein E signature and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
YP_002343408.1	NMA2160, conserved hypothetical protein, len: 148aa; similar to many eg. SW:P44110 (YEAL_HAEIN) hypothetical protein from Haemophilus influenzae (150 aa) fasta scores; E(): 0, 63.3% identity in 147 aa overlap.
YP_002343409.1	NMA2161, ispB, octaprenyl-diphosphate synthase,len: 324aa; similar to many eg. SW:P19641 (ISPB_ECOLI) ispB, octaprenyl-diphosphate synthase from Escherichia coli (323 aa) fasta scores; E(): 0, 53.4% identity in 320 aa overlap. Contains Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetases; Prosite match to PS00444 Polyprenyl synthetases signature 2 and Prosite match to PS00723 Polyprenyl synthetases signature 1.
YP_002343410.1	NMA2162, rplU, 50S ribosomal protein L21, len: 102aa; strongly similar to many eg. SW:P02422 (RL21_ECOLI) rplU, 50S ribosomal protein L21 from Escherichia coli (103 aa) fasta scores; E(): 5.3e-21, 54.9% identity in 102 aa overlap. Contains Pfam match to entry PF00829 Ribosomal_L21p, Ribosomal prokaryotic L21 protein and Prosite match to PS01169 Ribosomal protein L21 signature.
YP_002343411.1	involved in the peptidyltransferase reaction during translation
YP_002343412.1	NMA2164,  monooxygenase, len: 394aa; similar to many eg. SW:P25535 (VISC_ECOLI) hypothetical monooxygenase from Escherichia coli (400 aa) fasta scores; E(): 2.2e-27; 28.3% identity in 392 aa overlap and SW:P52019 (ERG1_MOUSE) squalene monooxygenase from Mus musculus (Mouse) (572 aa) fasta scores; E(): 0, 23.4% identity in 381 aa overlap. Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase.
YP_002343413.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_002343414.1	required for 70S ribosome assembly
YP_002343415.1	NMA2168, emrB, multidrug resistance translocase,len: 516aa; strongly similar to many eg. SW:P27304 (EMRB_ECOLI) emrB, multidrug resistance translocase (512 aa) fasta scores; E(): 0, 57.5% identity in 504 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343416.1	NMA2169, emrA, multidrug resistance translocase,len: 394aa; similar to many eg. SW:P27303 (EMRA_ECOLI) emrA, multidrug resistance translocase from Escherichia coli (390 aa) fasta scores; E(): 0, 44.8% identity in 386 aa overlap. Contains Pfam match to entry PF00529 HlyD,HlyD family secretion protein
YP_002343417.1	NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis
YP_002343418.1	NMA2171, conserved hypothetical inner membrane protein, len: 228aa; similar to many eg. SW:P37619 (YHHQ_ECOLI) hypothetical protein from Escherichia coli (221 aa) fasta scores; E(): 0, 66.5% identity in 209 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343419.1	NMA2172, conserved hypothetical protein, peptidase, len: 430aa; similar to many eg. SW:P44693 (YEBA_HAEIN) hypothetical protein from Haemophilus influenzae (475 aa) fasta scores; E(): 4.6e-23, 31.0% identity in 387 aa overlap. Contains Pfam match to entry PF01551 Peptidase_M37.
YP_002343420.1	NMA2173, hypothetical protein, len: 322aa
YP_002343421.1	NMA2174, conserved hypothetical protein, len: 490aa; similar to many eg. TR:Q9ZF57 (EMBL:AF118122) outer membrane protein from Neisseria meningitidis strain 8013#6 (488 aa) fasta scores; E(): 0,99.2% identity in 488 aa overlap and TR:O85049 (EMBL:AF039312) hypothetical protein from Moraxella catarrhalis (512 aa) fasta scores; E(): 0, 41.5% identity in 458 aa overlap.
YP_002343422.1	NMA2175, vapA,  virulence associated protein, len: 619aa; strongly similar to TR:Q9ZF58 (EMBL:AF118122) vapA, virulence associated protein from Neisseria meningitidis strain 8013#6 (619 aa) fasta scores; E(): 0, 98.4% identity in 619 aa overlap.
YP_002343423.1	NMA2176, hypothetical protein, len: 81aa
YP_002343424.1	NMA2177, conserved hypothetical inner membrane protein, len: 145aa; similar to many eg. TR:Q9ZJD5 (EMBL:AE001560) hypothetical protein from Helicobacter pylori J99 (148 aa) fasta scores; E(): 3.9e-15, 40.7% identity in 145 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343425.1	NMA2178, conserved hypothetical protein, len: 158aa; similar to TR:Q55960 (EMBL:D64005) hypothetical protein from Synechocystis sp. (strain PCC 6803) (154 aa) fasta scores; E(): 5.8e-28, 44.5% identity in 155 aa overlap.
YP_002343426.1	NMA2179, folA, dihydrofolate reductase, len: 162aa; similar to many eg. SW:P12833 (DYR3_SALTY) dhfrIII,dihydrofolate reductase type III from Salmonella typhimurium (162 aa) fasta scores; E(): 2.1e-26, 50.7% identity in 152 aa overlap. Contains Pfam match to entry PF00186 DiHfolate_red, Dihydrofolate reductase and Prosite match to PS00075 Dihydrofolate reductase signature.
YP_002343427.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_002343428.1	NMA2181, hypothetical protein (improbable CDS),len: 121aa
YP_002343429.1	NMA2182, hypothetical protein (improbable CDS),len: 30aa
YP_002343430.1	NMA2185, insertion element IS1016C2  transposase, len: 217aa; similar to many eg. TR:Q48234 (EMBL:X59756) insertion sequence IS1016-V6 from Haemophilus influenzae (191 aa) fasta scores; E(): 0,70.3% identity in 175 aa overlap. Also highly similar to many others from Neisseria meningitidis eg. NMA0471,NMA0769.
YP_002343431.1	NMA2186, hypothetical protein, len: 152aa; similar to TR:CAB44963 (EMBL:AJ242838) hypothetical protein from Neisseria meningitidis serogroup C strain FAM18 (148 aa) fasta scores; E(): 0, 97.2% identity in 145 aa overlap
YP_002343432.1	NMA2187,  DNA transport competence protein,len: 154 aa; region of similarity to SW:P39694 (CME1_BACSU) ComE a late competence operon protein from Bacillus subtilis (205 aa) fasta scores; E(): 9.8e-07,47.6% identity in 63 aa overlap. Previously sequenced therefore identical to TR:CAB44958 (EMBL:AJ242837) ComEA protein (fragment) from Neisseria meningitidis serogroup A strain Z2491 (170 aa) fasta scores; E(): 0, 100.0% identity in 154 aa overlap. Contains Pfam match to entry PF00633 HHH, Helix-hairpin-helix motif and  membrane-spanning hydrophobic region. Identical to NMA1915, and almost identical to NMA0211 (98.7% identity in 154 aa overlap), and NMA0423 (98.7% identity in 154 aa overlap)
YP_002343433.1	NMA2189, hypothetical inner membrane protein, len: 268aa; weakly similar to many eg. TR:P76599 (EMBL:AE000347) hypothetical protein from Escherichia coli (288 aa) fasta scores; E(): 8.2e-13, 27.3% identity in 249 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343434.1	NMA2190, ffh, signal recognition particle protein,len: 456aa; strongly similar to many eg. SW:P07019 (SR54_ECOLI) ffh, signal recognition particle protein from Escherichia coli (453 aa) fasta scores; E(): 0, 67.3% identity in 455 aa overlap. Contains Pfam match to entry PF00448 SRP54, SRP54-type protein; Prosite match to PS00300 SRP54-type proteins GTP-binding domain signature and potential coiled-coil region close to the N-terminus.
YP_002343435.1	NMA2191,  thiol:disulphide interchange protein, len: 231aa; weakly similar to many eg. SW:P2499 (DSBA_ECOLI) DsbA, thiol:disulphide interchange protein from Escherichia coli (208 aa) fasta scores; E(): 5.3e-10,30.8% identity in 198 aa overlap. Also similar to NMA2209 (fasta scores; E(): 0, 73.5% identity in 230 aa overlap). Contains Pfam match to entry PF01323 DSBA, DSBA oxidoreductase and Prosite match to PS00194 Thioredoxin family active site. Contains a  cleavable N-terminal signal sequence.
YP_002343436.1	NMA2192, conserved hypothetical protein, len: 219aa; similar to TR:O25892 (EMBL:AE000635) hypothetical protein from Helicobacter pylori (Campylobacter pylori) (224 aa) fasta scores; E(): 0, 47.5% identity in 223 aa overlap. Lies in a region of unusually low GC content.
YP_002343437.1	NMA2193,  TonB-dependent receptor protein,len: 703aa; similar to many eg. SW:P48632 (FPVA_PSEAE) ferripyoverdine receptor from Pseudomonas aeruginosa (813 aa) fasta scores; E(): 2.4e-18, 24.1% identity in 602 aa overlap. Contains Pfam match to entry PF00593 TonB_boxC,TonB dependent receptor C-terminal region.
YP_002343438.1	NMA2195, hypothetical protein, len: 201aa; similar to SW:P37261 (YC08_YEAST) hypothetical protein from Saccharomyces cerevisiae (Baker's yeast) (192 aa) fasta scores; E(): 3.2e-12, 32.1% identity in 184 aa overlap.
YP_002343439.1	NMA2196, conserved hypothetical inner membrane protein, len: 132aa; similar to many eg. SW:P44069 (Y886_HAEIN) hypothetical protein from Haemophilus influenzae (134 aa) fasta scores; E(): 5.1e-24, 55.0% identity in 129 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343440.1	NMA2197, probable LysR-family transcriptional regulator, len: 303aa; similar to many eg. TR:AAD33772 (EMBL:AF139107) hypothetical transcriptional activator from Pseudomonas aeruginosa (306 aa) fasta scores; E(): 6.1e-29, 33.4% identity in 290 aa overlap. Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family and Prosite match to PS00044 Bacterial regulatory proteins, lysR family signature.
YP_002343441.1	NMA2198, phr, deoxyribodopyrimidine photolyase,len: 433aa; similar to many eg. SW:P00914 (PHR_ECOLI) phr,deoxyribodopyrimidine photolyase from Escherichia coli (472 aa) fasta scores; E(): 8.2e-15, 30.4% identity in 457 aa overlap. Contains Pfam match to entry PF00875 DNA_photolyase, DNA photolyase and Prosite match to PS00394 DNA photolyases class 1 signature 1.
YP_002343442.1	NMA2199, hypothetical inner membrane protein, len: 76aa; contains  membrane-spanning hydrophobic regions.
YP_002343443.1	helicase involved in DNA repair and perhaps also replication
YP_002343444.1	NMA2201, hypothetical protein, len: 204aa; similar to SW:P33218 (YEBE_ECOLI) hypothetical protein from Escherichia coli (219 aa) fasta scores; E(): 3.1e-07,29.2% identity in 212 aa overlap.
YP_002343445.1	NMA2202,  inner membrane trans-acylase, len: 622aa; similar to TR:P74874 (EMBL:U65941) OafA integral membrane trans-acylase from Salmonella typhimurium (609 aa) fasta scores; E(): 4.9e-23, 31.4% identity in 488 aa overlap. Regions of similarity to others eg. 40-280aa similar to SW:P43993 (Y392_HAEIN) hypothetical protein from Haemophilus influenzae (245 aa) fasta scores; E(): 0, 60.7% identity in 239 aa overlap. Contains membrane-spanning hydrophobic regions.
YP_002343446.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_002343447.1	NMA2204, hypothetical protein, len: 210aa; similar to TR:Q46063 (EMBL:X81379) hypothetical protein from Corynebacterium glutamicum (211 aa) fasta scores; E(): 5.7e-30, 52.5% identity in 160 aa overlap.
YP_002343448.1	NMA2205, hypothetical protein, len: 635aa
YP_002343449.1	NMA2206,  rotamase, len: 347aa; weakly similar to many eg. SW:P21202 (SURA_ECOLI) SurA, survival protein from Escherichia coli (428 aa) fasta scores; E(): 4.7e-09, 26.1% identity in 303 aa overlap. Contains Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain and PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature
YP_002343450.1	NMA2207,  solvent tolerance protein, len: 802aa; similar to SW:P31554 (OSTA_ECOLI) solvent tolerance protein from Escherichia coli (784 aa) fasta scores; E(): 1.4e-30, 27.9% identity in 768 aa overlap.
YP_002343451.1	NMA2208, hypothetical protein, len: 334aa; similar to TR:AAD22455 (EMBL:AF116284) hypothetical protein from Pseudomonas aeruginosa (338 aa) fasta scores; E(): 0,44.0% identity in 332 aa overlap.
YP_002343452.1	NMA2209,  thiol:disulphide interchange protein, len: 232aa; weakly similar to many eg. SW:P52234 (DSBA_ERWCH) DsbA, thiol:disulphide interchange protein from Erwinia chrysanthemi (207 aa) fasta scores; E(): 7e-06, 26.4% identity in 193 aa overlap. Also similar to NMA2191 (fasta scores; E(): 0, 73.5% identity in 230 aa overlap). Contains Pfam match to entry PF01323 DSBA, DSBA oxidoreductase and Prosite match to PS00194 Thioredoxin family active site. Contains a  cleavable N-terminal signal sequence.
YP_002343453.1	NMA2210,  inner membrane virulence factor protein, len: 512aa; similar to many MviN virulence factor homologs eg. SW:P37169 (MVIN_SALTY) from Salmonella typhimurium (524 aa) fasta scores; E(): 0, 63.5% identity in 509 aa overlap. Contains  membrane-spanning hydrophobic regions.
YP_002343454.1	NMA2211, conserved hypothetical protein, len: 318aa; similar to many eg. SW:P45524 (YHET_ECOLI) hypothetical protein from Escherichia coli (340 aa) fasta scores; E(): 0, 36.6% identity in 314 aa overlap. Contains PS01133 Uncharacterized protein family UPF0017 signature.
YP_002343455.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_002343456.1	NMA2213, recQ, ATP-dependent DNA helicase, len: 801aa; similar to many eg. SW:P15043 (RECQ_ECOLI) recQ,ATP-dependent DNA helicase from Escherichia coli (607 aa) fasta scores; E(): 0, 47.1% identity in 594 aa overlap. Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase; Pfam match to entry PF00271 helicase_C,Helicases conserved C-terminal domain and two Pfam matches to entry PF00570 HRDC, HRDC domain.
YP_002343457.1	NMA2214, hypothetical protein, len: 208aa
YP_002343458.1	NMA2215, hypothetical protein, len: 262aa
YP_002343459.1	NMA2216,  hydrolase, len: 312aa; similar to TR:O67982 (EMBL:AF003947) 3-oxoadipate enol-lactone-hydrolase/4-carboxymuconolactone-decarboxyla se from Rhodococcus opacus (400 aa) fasta scores; E(): 3.9e-10, 28.7% identity in 265 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.
YP_002343460.1	NMA2217, hypothetical protein, len: 246aa; similar to others of undefined function eg. SW:P31773 (COMF_HAEIN) competence protein from Haemophilus influenzae (229 aa) fasta scores; E(): 1.4e-17, 32.5% identity in 231 aa overlap.
YP_002343461.1	NMA2218,  tRNA/rRNA methyltransferase, len: 154aa; similar to many eg. SW:P33899 (YIBK_ECOLI) hypothetical tRNA/rRNA methyltransferase from Escherichia coli (157 aa) fasta scores; E(): 0, 62.3% identity in 154 aa overlap. Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family.
YP_002343462.1	NMA2219,  periplasmic protein, len: 239aa; weakly similar to many of undefined function eg. TRNEW:AAD32233 (EMBL:AF147448) from Pseudomonas aeruginosa (342 aa) fasta scores; E(): 4.2e-24, 40.5% identity in 232 aa overlap.
YP_002343463.1	NMA2220, hypothetical protein, len: 126aa
YP_002343464.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_002343465.1	NMA2223, probable ABC transporter, len: 618aa; similar to many eg. SW:Q57180 (YA51_HAEIN) hypothetical ABC transporter from Haemophilus influenzae (614 aa) fasta scores; E(): 0, 76.5% identity in 614 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter; Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop) and Prosite match to PS00211 ABC transporters family signature
YP_002343466.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_002343467.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
YP_002343468.1	NMA2226, ispA, geranyltranstransferase, len: 298aa; similar to many eg. SW:P22939 (ISPA_ECOLI) ispA,geranyltranstransferase from Escherichia coli (299 aa) fasta scores; E(): 0, 49.1% identity in 289 aa overlap. Contains Pfam match to entry PF00348 polyprenyl_synt,Polyprenyl synthetases; Prosite match to PS00723 Polyprenyl synthetases signature 1 and Prosite match to PS00444 Polyprenyl synthetases signature 2.
YP_002343469.1	NMA2227, hypothetical inner membrane protein, len: 116aa; Contains  membrane-spanning hydrophobic regions.
YP_002343470.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002343471.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002343472.1	NMA2230, hypothetical protein, len: 571aa; weakly similar to many eg. TR:O34810 (EMBL:AE000641) hypothetical protein from Helicobacter pylori (Campylobacter pylori) (578 aa) fasta scores; E(): 3e-21, 23.2% identity in 604 aa overlap. Lies in a region of unusually low GC content.