-- dump date   	20140619_164509
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
228410000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
228410000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
228410000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410000004	Walker A motif; other site
228410000005	ATP binding site [chemical binding]; other site
228410000006	Walker B motif; other site
228410000007	arginine finger; other site
228410000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
228410000009	DnaA box-binding interface [nucleotide binding]; other site
228410000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
228410000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
228410000012	putative DNA binding surface [nucleotide binding]; other site
228410000013	dimer interface [polypeptide binding]; other site
228410000014	beta-clamp/clamp loader binding surface; other site
228410000015	beta-clamp/translesion DNA polymerase binding surface; other site
228410000016	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
228410000017	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410000018	Mg2+ binding site [ion binding]; other site
228410000019	G-X-G motif; other site
228410000020	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
228410000021	anchoring element; other site
228410000022	dimer interface [polypeptide binding]; other site
228410000023	ATP binding site [chemical binding]; other site
228410000024	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
228410000025	active site
228410000026	putative metal-binding site [ion binding]; other site
228410000027	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
228410000028	hypothetical protein; Provisional; Region: PRK10527
228410000029	3 probable transmembrane helices predicted by TMHMM2.0
228410000030	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
228410000031	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
228410000032	RNA binding surface [nucleotide binding]; other site
228410000033	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
228410000034	active site
228410000035	Ferredoxin [Energy production and conversion]; Region: COG1146
228410000036	4Fe-4S binding domain; Region: Fer4; cl02805
228410000037	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
228410000038	putative exosortase-associated protein, TIGR04073 family; Region: exo_TIGR04073
228410000039	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.953 at residue 24
228410000040	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
228410000041	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
228410000042	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410000043	ATP binding site [chemical binding]; other site
228410000044	putative Mg++ binding site [ion binding]; other site
228410000045	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410000046	nucleotide binding region [chemical binding]; other site
228410000047	ATP-binding site [chemical binding]; other site
228410000048	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
228410000049	MgtC family; Region: MgtC; pfam02308
228410000050	Predicted membrane protein [Function unknown]; Region: COG3174
228410000051	Domain of unknown function (DUF4010); Region: DUF4010; pfam13194
228410000052	14 probable transmembrane helices predicted by TMHMM2.0
228410000053	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
228410000054	DHH family; Region: DHH; pfam01368
228410000055	DHHA1 domain; Region: DHHA1; pfam02272
228410000056	1 probable transmembrane helix predicted by TMHMM2.0
228410000057	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.995 at residue 27
228410000058	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
228410000059	active site
228410000060	ribulose/triose binding site [chemical binding]; other site
228410000061	phosphate binding site [ion binding]; other site
228410000062	substrate (anthranilate) binding pocket [chemical binding]; other site
228410000063	product (indole) binding pocket [chemical binding]; other site
228410000064	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
228410000065	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
228410000066	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
228410000067	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
228410000068	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
228410000069	glutamine binding [chemical binding]; other site
228410000070	catalytic triad [active]
228410000071	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
228410000072	HAMP domain; Region: HAMP; pfam00672
228410000073	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410000074	dimer interface [polypeptide binding]; other site
228410000075	phosphorylation site [posttranslational modification]
228410000076	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410000077	ATP binding site [chemical binding]; other site
228410000078	Mg2+ binding site [ion binding]; other site
228410000079	G-X-G motif; other site
228410000080	2 probable transmembrane helices predicted by TMHMM2.0
228410000081	response regulator GlrR; Provisional; Region: PRK15115
228410000082	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410000083	active site
228410000084	phosphorylation site [posttranslational modification]
228410000085	intermolecular recognition site; other site
228410000086	dimerization interface [polypeptide binding]; other site
228410000087	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410000088	Walker A motif; other site
228410000089	ATP binding site [chemical binding]; other site
228410000090	Walker B motif; other site
228410000091	arginine finger; other site
228410000092	Protein of unknown function, DUF399; Region: DUF399; pfam04187
228410000093	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
228410000094	protein binding site [polypeptide binding]; other site
228410000095	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
228410000096	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
228410000097	dimerization interface [polypeptide binding]; other site
228410000098	ATP binding site [chemical binding]; other site
228410000099	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
228410000100	dimerization interface [polypeptide binding]; other site
228410000101	ATP binding site [chemical binding]; other site
228410000102	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
228410000103	putative active site [active]
228410000104	catalytic triad [active]
228410000105	Uncharacterized conserved protein [Function unknown]; Region: COG0062
228410000106	putative carbohydrate kinase; Provisional; Region: PRK10565
228410000107	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
228410000108	putative substrate binding site [chemical binding]; other site
228410000109	putative ATP binding site [chemical binding]; other site
228410000110	hypothetical protein; Provisional; Region: PRK10756
228410000111	CreA protein; Region: CreA; pfam05981
228410000112	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.914) with cleavage site probability 0.913 at residue 40
228410000113	1 probable transmembrane helix predicted by TMHMM2.0
228410000114	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
228410000115	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
228410000116	hexamer interface [polypeptide binding]; other site
228410000117	ligand binding site [chemical binding]; other site
228410000118	putative active site [active]
228410000119	NAD(P) binding site [chemical binding]; other site
228410000120	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
228410000121	putative catalytic site [active]
228410000122	putative phosphate binding site [ion binding]; other site
228410000123	active site
228410000124	metal binding site A [ion binding]; metal-binding site
228410000125	DNA binding site [nucleotide binding]
228410000126	putative AP binding site [nucleotide binding]; other site
228410000127	putative metal binding site B [ion binding]; other site
228410000128	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
228410000129	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
228410000130	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
228410000131	Beta-Casp domain; Region: Beta-Casp; smart01027
228410000132	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
228410000133	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
228410000134	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06943
228410000135	inhibitor-cofactor binding pocket; inhibition site
228410000136	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410000137	catalytic residue [active]
228410000138	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
228410000139	oligomerisation interface [polypeptide binding]; other site
228410000140	mobile loop; other site
228410000141	roof hairpin; other site
228410000142	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
228410000143	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
228410000144	ring oligomerisation interface [polypeptide binding]; other site
228410000145	ATP/Mg binding site [chemical binding]; other site
228410000146	stacking interactions; other site
228410000147	hinge regions; other site
228410000148	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
228410000149	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
228410000150	NADP binding site [chemical binding]; other site
228410000151	homodimer interface [polypeptide binding]; other site
228410000152	active site
228410000153	trigger factor; Provisional; Region: tig; PRK01490
228410000154	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
228410000155	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
228410000156	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
228410000157	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
228410000158	oligomer interface [polypeptide binding]; other site
228410000159	active site residues [active]
228410000160	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
228410000161	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
228410000162	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410000163	Walker A motif; other site
228410000164	ATP binding site [chemical binding]; other site
228410000165	Walker B motif; other site
228410000166	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
228410000167	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
228410000168	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410000169	Walker A motif; other site
228410000170	ATP binding site [chemical binding]; other site
228410000171	Walker B motif; other site
228410000172	arginine finger; other site
228410000173	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
228410000174	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
228410000175	homodimer interface [polypeptide binding]; other site
228410000176	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410000177	catalytic residue [active]
228410000178	AAA domain; Region: AAA_32; pfam13654
228410000179	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
228410000180	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
228410000181	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.996 at residue 25
228410000182	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
228410000183	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410000184	S-adenosylmethionine binding site [chemical binding]; other site
228410000185	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
228410000186	ThiC-associated domain; Region: ThiC-associated; pfam13667
228410000187	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
228410000188	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
228410000189	7 probable transmembrane helices predicted by TMHMM2.0
228410000190	Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522
228410000191	active site residue [active]
228410000192	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
228410000193	substrate binding site [chemical binding]; other site
228410000194	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
228410000195	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
228410000196	active site
228410000197	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 38
228410000198	1 probable transmembrane helix predicted by TMHMM2.0
228410000199	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
228410000200	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
228410000201	active site
228410000202	HIGH motif; other site
228410000203	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
228410000204	KMSKS motif; other site
228410000205	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
228410000206	tRNA binding surface [nucleotide binding]; other site
228410000207	anticodon binding site; other site
228410000208	Methyltransferase domain; Region: Methyltransf_18; pfam12847
228410000209	3 probable transmembrane helices predicted by TMHMM2.0
228410000210	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
228410000211	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
228410000212	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
228410000213	ligand binding site [chemical binding]; other site
228410000214	1 probable transmembrane helix predicted by TMHMM2.0
228410000215	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
228410000216	flagellar motor protein MotA; Validated; Region: PRK09110
228410000217	4 probable transmembrane helices predicted by TMHMM2.0
228410000218	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
228410000219	nucleoside/Zn binding site; other site
228410000220	dimer interface [polypeptide binding]; other site
228410000221	catalytic motif [active]
228410000222	class II aldolase/adducin domain protein; Provisional; Region: PRK07090
228410000223	intersubunit interface [polypeptide binding]; other site
228410000224	active site
228410000225	Zn2+ binding site [ion binding]; other site
228410000226	Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]; Region: COG4191
228410000227	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
228410000228	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410000229	dimerization interface [polypeptide binding]; other site
228410000230	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
228410000231	putative active site [active]
228410000232	heme pocket [chemical binding]; other site
228410000233	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410000234	dimer interface [polypeptide binding]; other site
228410000235	phosphorylation site [posttranslational modification]
228410000236	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410000237	ATP binding site [chemical binding]; other site
228410000238	G-X-G motif; other site
228410000239	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
228410000240	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410000241	active site
228410000242	phosphorylation site [posttranslational modification]
228410000243	intermolecular recognition site; other site
228410000244	dimerization interface [polypeptide binding]; other site
228410000245	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
228410000246	putative binding surface; other site
228410000247	active site
228410000248	2 probable transmembrane helices predicted by TMHMM2.0
228410000249	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
228410000250	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
228410000251	CoA-ligase; Region: Ligase_CoA; pfam00549
228410000252	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
228410000253	CoA binding domain; Region: CoA_binding; smart00881
228410000254	CoA-ligase; Region: Ligase_CoA; pfam00549
228410000255	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.744) with cleavage site probability 0.592 at residue 27
228410000256	1 probable transmembrane helix predicted by TMHMM2.0
228410000257	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027
228410000258	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 22
228410000259	1 probable transmembrane helix predicted by TMHMM2.0
228410000260	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
228410000261	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410000262	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410000263	Walker A/P-loop; other site
228410000264	ATP binding site [chemical binding]; other site
228410000265	Q-loop/lid; other site
228410000266	ABC transporter signature motif; other site
228410000267	Walker B; other site
228410000268	6 probable transmembrane helices predicted by TMHMM2.0
228410000269	intracellular septation protein A; Reviewed; Region: PRK00259
228410000270	5 probable transmembrane helices predicted by TMHMM2.0
228410000271	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
228410000272	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
228410000273	minor groove reading motif; other site
228410000274	helix-hairpin-helix signature motif; other site
228410000275	substrate binding pocket [chemical binding]; other site
228410000276	active site
228410000277	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
228410000278	DNA binding and oxoG recognition site [nucleotide binding]
228410000279	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
228410000280	aromatic acid decarboxylase; Validated; Region: PRK05920
228410000281	Flavoprotein; Region: Flavoprotein; pfam02441
228410000282	HPr kinase/phosphorylase; Provisional; Region: PRK05428
228410000283	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
228410000284	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
228410000285	Hpr binding site; other site
228410000286	active site
228410000287	homohexamer subunit interaction site [polypeptide binding]; other site
228410000288	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
228410000289	active site
228410000290	phosphorylation site [posttranslational modification]
228410000291	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
228410000292	30S subunit binding site; other site
228410000293	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
228410000294	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
228410000295	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
228410000296	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
228410000297	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
228410000298	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
228410000299	Walker A/P-loop; other site
228410000300	ATP binding site [chemical binding]; other site
228410000301	Q-loop/lid; other site
228410000302	ABC transporter signature motif; other site
228410000303	Walker B; other site
228410000304	D-loop; other site
228410000305	H-loop/switch region; other site
228410000306	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
228410000307	OstA-like protein; Region: OstA; pfam03968
228410000308	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.938) with cleavage site probability 0.932 at residue 44
228410000309	1 probable transmembrane helix predicted by TMHMM2.0
228410000310	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
228410000311	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117; cl01200
228410000312	quinolinate synthetase; Provisional; Region: PRK09375
228410000313	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
228410000314	putative catalytic site [active]
228410000315	putative metal binding site [ion binding]; other site
228410000316	putative phosphate binding site [ion binding]; other site
228410000317	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
228410000318	putative active site [active]
228410000319	catalytic site [active]
228410000320	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
228410000321	PLD-like domain; Region: PLDc_2; pfam13091
228410000322	putative active site [active]
228410000323	catalytic site [active]
228410000324	poly(A) polymerase; Region: pcnB; TIGR01942
228410000325	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
228410000326	active site
228410000327	NTP binding site [chemical binding]; other site
228410000328	metal binding triad [ion binding]; metal-binding site
228410000329	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
228410000330	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
228410000331	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
228410000332	catalytic center binding site [active]
228410000333	ATP binding site [chemical binding]; other site
228410000334	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
228410000335	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
228410000336	Substrate-binding site [chemical binding]; other site
228410000337	Substrate specificity [chemical binding]; other site
228410000338	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
228410000339	oligomerization interface [polypeptide binding]; other site
228410000340	active site
228410000341	metal binding site [ion binding]; metal-binding site
228410000342	pantoate--beta-alanine ligase; Region: panC; TIGR00018
228410000343	Pantoate-beta-alanine ligase; Region: PanC; cd00560
228410000344	active site
228410000345	ATP-binding site [chemical binding]; other site
228410000346	pantoate-binding site; other site
228410000347	HXXH motif; other site
228410000348	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
228410000349	putative homodimer interface [polypeptide binding]; other site
228410000350	putative active site pocket [active]
228410000351	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
228410000352	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
228410000353	catalytic site [active]
228410000354	putative active site [active]
228410000355	putative substrate binding site [chemical binding]; other site
228410000356	dimer interface [polypeptide binding]; other site
228410000357	Peptidase family M48; Region: Peptidase_M48; pfam01435
228410000358	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.626) with cleavage site probability 0.624 at residue 31
228410000359	7 probable transmembrane helices predicted by TMHMM2.0
228410000360	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_a; cd00913
228410000361	aromatic arch; other site
228410000362	DCoH dimer interaction site [polypeptide binding]; other site
228410000363	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
228410000364	DCoH tetramer interaction site [polypeptide binding]; other site
228410000365	substrate binding site [chemical binding]; other site
228410000366	GTPase RsgA; Reviewed; Region: PRK00098
228410000367	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
228410000368	RNA binding site [nucleotide binding]; other site
228410000369	homodimer interface [polypeptide binding]; other site
228410000370	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
228410000371	GTPase/Zn-binding domain interface [polypeptide binding]; other site
228410000372	GTP/Mg2+ binding site [chemical binding]; other site
228410000373	G4 box; other site
228410000374	G5 box; other site
228410000375	G1 box; other site
228410000376	Switch I region; other site
228410000377	G2 box; other site
228410000378	G3 box; other site
228410000379	Switch II region; other site
228410000380	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
228410000381	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 at residue 25
228410000382	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
228410000383	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
228410000384	active site
228410000385	phosphorylation site [posttranslational modification]
228410000386	intermolecular recognition site; other site
228410000387	dimerization interface [polypeptide binding]; other site
228410000388	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
228410000389	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
228410000390	metal binding site [ion binding]; metal-binding site
228410000391	active site
228410000392	I-site; other site
228410000393	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410000394	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
228410000395	4 probable transmembrane helices predicted by TMHMM2.0
228410000396	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.850 at residue 25
228410000397	1 probable transmembrane helix predicted by TMHMM2.0
228410000398	Glycine-zipper containing OmpA-like membrane domain; Region: Gly-zipper_OmpA; pfam13436
228410000399	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.982) with cleavage site probability 0.351 at residue 19
228410000400	1 probable transmembrane helix predicted by TMHMM2.0
228410000401	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
228410000402	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
228410000403	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410000404	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
228410000405	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 20
228410000406	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
228410000407	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
228410000408	active site
228410000409	substrate binding site [chemical binding]; other site
228410000410	cosubstrate binding site; other site
228410000411	catalytic site [active]
228410000412	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
228410000413	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
228410000414	dimerization interface [polypeptide binding]; other site
228410000415	putative ATP binding site [chemical binding]; other site
228410000416	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
228410000417	Domain of unknown function DUF20; Region: UPF0118; pfam01594
228410000418	8 probable transmembrane helices predicted by TMHMM2.0
228410000419	Sterile alpha motif; Region: SAM; smart00454
228410000420	SAM (Sterile alpha motif ); Region: SAM_superfamily; cd09487
228410000421	TOMM system kinase/cyclase fusion protein; Region: TOMM_kin_cyc; TIGR03903
228410000422	cyclase homology domain; Region: CHD; cd07302
228410000423	nucleotidyl binding site; other site
228410000424	metal binding site [ion binding]; metal-binding site
228410000425	dimer interface [polypeptide binding]; other site
228410000426	AAA ATPase domain; Region: AAA_16; pfam13191
228410000427	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
228410000428	Ligand Binding Site [chemical binding]; other site
228410000429	ABC1 family; Region: ABC1; cl17513
228410000430	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
228410000431	1 probable transmembrane helix predicted by TMHMM2.0
228410000432	Uncharacterized conserved protein [Function unknown]; Region: COG1479
228410000433	Protein of unknown function DUF262; Region: DUF262; pfam03235
228410000434	DEAD-like helicases superfamily; Region: DEXDc; smart00487
228410000435	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410000436	ATP binding site [chemical binding]; other site
228410000437	putative Mg++ binding site [ion binding]; other site
228410000438	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410000439	nucleotide binding region [chemical binding]; other site
228410000440	ATP-binding site [chemical binding]; other site
228410000441	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
228410000442	Part of AAA domain; Region: AAA_19; pfam13245
228410000443	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
228410000444	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
228410000445	Family description; Region: UvrD_C_2; pfam13538
228410000446	GMP synthase; Reviewed; Region: guaA; PRK00074
228410000447	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
228410000448	AMP/PPi binding site [chemical binding]; other site
228410000449	candidate oxyanion hole; other site
228410000450	catalytic triad [active]
228410000451	potential glutamine specificity residues [chemical binding]; other site
228410000452	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
228410000453	ATP Binding subdomain [chemical binding]; other site
228410000454	Ligand Binding sites [chemical binding]; other site
228410000455	Dimerization subdomain; other site
228410000456	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
228410000457	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
228410000458	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
228410000459	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
228410000460	active site
228410000461	putative exosortase-associated protein, TIGR04073 family; Region: exo_TIGR04073
228410000462	1 probable transmembrane helix predicted by TMHMM2.0
228410000463	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.990 at residue 25
228410000464	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
228410000465	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
228410000466	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
228410000467	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410000468	Walker A motif; other site
228410000469	ATP binding site [chemical binding]; other site
228410000470	Walker B motif; other site
228410000471	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
228410000472	arginine finger; other site
228410000473	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
228410000474	metabolite-proton symporter; Region: 2A0106; TIGR00883
228410000475	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
228410000476	putative substrate translocation pore; other site
228410000477	12 probable transmembrane helices predicted by TMHMM2.0
228410000478	glycerate dehydrogenase; Provisional; Region: PRK06487
228410000479	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
228410000480	putative ligand binding site [chemical binding]; other site
228410000481	putative NAD binding site [chemical binding]; other site
228410000482	catalytic site [active]
228410000483	Cytochrome c; Region: Cytochrom_C; cl11414
228410000484	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 24
228410000485	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
228410000486	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
228410000487	catalytic residues [active]
228410000488	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
228410000489	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
228410000490	7 probable transmembrane helices predicted by TMHMM2.0
228410000491	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
228410000492	Permease; Region: Permease; pfam02405
228410000493	6 probable transmembrane helices predicted by TMHMM2.0
228410000494	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
228410000495	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
228410000496	Walker A/P-loop; other site
228410000497	ATP binding site [chemical binding]; other site
228410000498	Q-loop/lid; other site
228410000499	ABC transporter signature motif; other site
228410000500	Walker B; other site
228410000501	D-loop; other site
228410000502	H-loop/switch region; other site
228410000503	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
228410000504	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
228410000505	metal binding site [ion binding]; metal-binding site
228410000506	dimer interface [polypeptide binding]; other site
228410000507	1 probable transmembrane helix predicted by TMHMM2.0
228410000508	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
228410000509	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cd09634
228410000510	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
228410000511	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cd09686
228410000512	CRISPR-associated (Cas) DxTHG family; Region: Cas_DxTHG; pfam09455
228410000513	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cd09668
228410000514	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cl17439
228410000515	CRISPR/Cas system-associated protein Csx16; Region: Csx16_III-U; cd09743
228410000516	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cl11443
228410000517	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
228410000518	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
228410000519	CRISPR/Cas system-associated RAMP superfamily protein Csm5; Region: Csm5_III-A; cl17437
228410000520	CRISPR/Cas system-associated RAMP superfamily protein Csm4; Region: Csm4_III-A; cl17438
228410000521	CRISPR/Cas system-associated RAMP superfamily protein Csm3; Region: Csm3_III-A; cd09684
228410000522	CRISPR/Cas system-associated protein Csm2; Region: Csm2_III-A; cd09647
228410000523	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cd09680
228410000524	CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE; Region: cas_TM1811_Csm1; TIGR02578
228410000525	NE0126, NE0125 and NE0124 are parts of a pseudogene caused by at least 2 frameshifts, possible TonB-dependent receptor protein
228410000526	fec operon regulator FecR; Reviewed; Region: PRK09774
228410000527	FecR protein; Region: FecR; pfam04773
228410000528	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410000529	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410000530	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410000531	DNA binding residues [nucleotide binding]
228410000532	BON domain; Region: BON; pfam04972
228410000533	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.385 at residue 30
228410000534	2 probable transmembrane helices predicted by TMHMM2.0
228410000535	CsbD-like; Region: CsbD; cl17424
228410000536	BON domain; Region: BON; pfam04972
228410000537	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.795 at residue 26
228410000538	NE0133 and NE0135 are two parts of a pseudogene caused by the interruption of an IS element
228410000539	NE0133 and NE0135 are 2 parts of a dead gene due to IS element insertion;PAS domain
228410000540	ISNE7
228410000541	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
228410000542	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; cl01481
228410000543	NE0133 and NE0135 are 2 parts of a dead gene due to IS element insertion;probable transcriptional regulator
228410000544	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.959 at residue 21
228410000545	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
228410000546	catalytic residues [active]
228410000547	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
228410000548	Methyltransferase domain; Region: Methyltransf_11; pfam08241
228410000549	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
228410000550	RNA/DNA hybrid binding site [nucleotide binding]; other site
228410000551	active site
228410000552	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
228410000553	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
228410000554	active site
228410000555	catalytic site [active]
228410000556	substrate binding site [chemical binding]; other site
228410000557	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
228410000558	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
228410000559	inhibitor-cofactor binding pocket; inhibition site
228410000560	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410000561	catalytic residue [active]
228410000562	nitrosocyanin; Region: nitroso_cyanin; TIGR03096
228410000563	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.828 at residue 25
228410000564	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
228410000565	active site
228410000566	multimer interface [polypeptide binding]; other site
228410000567	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
228410000568	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410000569	FeS/SAM binding site; other site
228410000570	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.964) with cleavage site probability 0.426 at residue 27
228410000571	type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521
228410000572	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410000573	binding surface
228410000574	TPR motif; other site
228410000575	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410000576	TPR motif; other site
228410000577	binding surface
228410000578	Helix-turn-helix domain; Region: HTH_25; pfam13413
228410000579	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
228410000580	1 probable transmembrane helix predicted by TMHMM2.0
228410000581	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
228410000582	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
228410000583	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
228410000584	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
228410000585	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
228410000586	dimer interface [polypeptide binding]; other site
228410000587	motif 1; other site
228410000588	active site
228410000589	motif 2; other site
228410000590	motif 3; other site
228410000591	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
228410000592	anticodon binding site; other site
228410000593	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
228410000594	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
228410000595	1 probable transmembrane helix predicted by TMHMM2.0
228410000596	outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300
228410000597	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
228410000598	Trp docking motif [polypeptide binding]; other site
228410000599	active site
228410000600	1 probable transmembrane helix predicted by TMHMM2.0
228410000601	GTP-binding protein Der; Reviewed; Region: PRK00093
228410000602	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
228410000603	G1 box; other site
228410000604	GTP/Mg2+ binding site [chemical binding]; other site
228410000605	Switch I region; other site
228410000606	G2 box; other site
228410000607	Switch II region; other site
228410000608	G3 box; other site
228410000609	G4 box; other site
228410000610	G5 box; other site
228410000611	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
228410000612	G1 box; other site
228410000613	GTP/Mg2+ binding site [chemical binding]; other site
228410000614	Switch I region; other site
228410000615	G2 box; other site
228410000616	G3 box; other site
228410000617	Switch II region; other site
228410000618	G4 box; other site
228410000619	G5 box; other site
228410000620	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
228410000621	Transposase; Region: HTH_Tnp_1; pfam01527
228410000622	putative transposase OrfB; Reviewed; Region: PHA02517
228410000623	Integrase core domain; Region: rve; pfam00665
228410000624	Integrase core domain; Region: rve_2; pfam13333
228410000625	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410000626	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
228410000627	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410000628	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.771) with cleavage site probability 0.656 at residue 28
228410000629	1 probable transmembrane helix predicted by TMHMM2.0
228410000630	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
228410000631	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.789) with cleavage site probability 0.458 at residue 29
228410000632	12 probable transmembrane helices predicted by TMHMM2.0
228410000633	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
228410000634	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410000635	1 probable transmembrane helix predicted by TMHMM2.0
228410000636	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
228410000637	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cd02259
228410000638	putative active site [active]
228410000639	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410000640	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
228410000641	Walker A/P-loop; other site
228410000642	ATP binding site [chemical binding]; other site
228410000643	Q-loop/lid; other site
228410000644	ABC transporter signature motif; other site
228410000645	Walker B; other site
228410000646	D-loop; other site
228410000647	H-loop/switch region; other site
228410000648	3 probable transmembrane helices predicted by TMHMM2.0
228410000649	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
228410000650	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.798) with cleavage site probability 0.784 at residue 17
228410000651	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
228410000652	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
228410000653	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000654	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000655	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000656	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000657	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000658	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000659	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000660	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000661	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000662	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000663	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000664	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000665	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000666	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000667	cyanobacterial long protein repeat; Region: swm_rep_I; TIGR02059
228410000668	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
228410000669	ISNE1
228410000670	Winged helix-turn helix; Region: HTH_29; pfam13551
228410000671	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410000672	Homeodomain-like domain; Region: HTH_32; pfam13565
228410000673	Integrase core domain; Region: rve; pfam00665
228410000674	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410000675	Integrase core domain; Region: rve_3; pfam13683
228410000676	dead gene, it is only the 5' half of the tranposase;Transposase IS911 HTH and LZ region
228410000677	5' half of transposase, the next gene downstream is also the 5' end of a transposase; transposase
228410000678	ISNE6 fragment
228410000679	3 probable transmembrane helices predicted by TMHMM2.0
228410000680	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
228410000681	Uncharacterized conserved protein [Function unknown]; Region: COG3461
228410000682	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
228410000683	12 probable transmembrane helices predicted by TMHMM2.0
228410000684	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410000685	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410000686	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410000687	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.956) with cleavage site probability 0.810 at residue 39
228410000688	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
228410000689	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.808) with cleavage site probability 0.796 at residue 26
228410000690	Protein of unknown function, DUF481; Region: DUF481; pfam04338
228410000691	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.860 at residue 23
228410000692	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
228410000693	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
228410000694	RNase E interface [polypeptide binding]; other site
228410000695	trimer interface [polypeptide binding]; other site
228410000696	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
228410000697	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
228410000698	RNase E interface [polypeptide binding]; other site
228410000699	trimer interface [polypeptide binding]; other site
228410000700	active site
228410000701	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
228410000702	putative nucleic acid binding region [nucleotide binding]; other site
228410000703	G-X-X-G motif; other site
228410000704	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
228410000705	RNA binding site [nucleotide binding]; other site
228410000706	domain interface; other site
228410000707	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
228410000708	16S/18S rRNA binding site [nucleotide binding]; other site
228410000709	S13e-L30e interaction site [polypeptide binding]; other site
228410000710	25S rRNA binding site [nucleotide binding]; other site
228410000711	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
228410000712	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
228410000713	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
228410000714	catalytic residue [active]
228410000715	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
228410000716	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
228410000717	active site
228410000718	metal-binding site
228410000719	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
228410000720	nucleotide binding site/active site [active]
228410000721	HIT family signature motif; other site
228410000722	catalytic residue [active]
228410000723	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
228410000724	Fatty acid desaturase; Region: FA_desaturase; pfam00487
228410000725	putative di-iron ligands [ion binding]; other site
228410000726	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
228410000727	6 probable transmembrane helices predicted by TMHMM2.0
228410000728	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
228410000729	catalytic core [active]
228410000730	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
228410000731	seryl-tRNA synthetase; Provisional; Region: PRK05431
228410000732	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
228410000733	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
228410000734	dimer interface [polypeptide binding]; other site
228410000735	active site
228410000736	motif 1; other site
228410000737	motif 2; other site
228410000738	motif 3; other site
228410000739	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
228410000740	active site
228410000741	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
228410000742	substrate binding site [chemical binding]; other site
228410000743	2 probable transmembrane helices predicted by TMHMM2.0
228410000744	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 at residue 29
228410000745	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
228410000746	nudix motif; other site
228410000747	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
228410000748	active site
228410000749	Modulator of Rho-dependent transcription termination (ROF); Region: ROF; pfam07073
228410000750	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.992 at residue 46
228410000751	ISNE1
228410000752	Winged helix-turn helix; Region: HTH_29; pfam13551
228410000753	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410000754	Homeodomain-like domain; Region: HTH_32; pfam13565
228410000755	Integrase core domain; Region: rve; pfam00665
228410000756	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410000757	Integrase core domain; Region: rve_3; pfam13683
228410000758	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410000759	salt bridge; other site
228410000760	non-specific DNA binding site [nucleotide binding]; other site
228410000761	sequence-specific DNA binding site [nucleotide binding]; other site
228410000762	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
228410000763	NTP_transferase_like_1 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_1; cd06422
228410000764	Substrate binding site; other site
228410000765	metal-binding site
228410000766	Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]; Region: COG3178
228410000767	Phosphotransferase enzyme family; Region: APH; pfam01636
228410000768	Membrane fusogenic activity; Region: BMFP; pfam04380
228410000769	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
228410000770	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
228410000771	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410000772	Walker A motif; other site
228410000773	ATP binding site [chemical binding]; other site
228410000774	Walker B motif; other site
228410000775	arginine finger; other site
228410000776	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
228410000777	replicative DNA helicase; Region: DnaB; TIGR00665
228410000778	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
228410000779	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
228410000780	Walker A motif; other site
228410000781	ATP binding site [chemical binding]; other site
228410000782	Walker B motif; other site
228410000783	DNA binding loops [nucleotide binding]
228410000784	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
228410000785	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
228410000786	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
228410000787	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
228410000788	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
228410000789	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
228410000790	ATP synthase I chain; Region: ATP_synt_I; cl09170
228410000791	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.895 at residue 36
228410000792	4 probable transmembrane helices predicted by TMHMM2.0
228410000793	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
228410000794	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
228410000795	5 probable transmembrane helices predicted by TMHMM2.0
228410000796	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
228410000797	2 probable transmembrane helices predicted by TMHMM2.0
228410000798	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
228410000799	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
228410000800	1 probable transmembrane helix predicted by TMHMM2.0
228410000801	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
228410000802	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
228410000803	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
228410000804	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
228410000805	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
228410000806	beta subunit interaction interface [polypeptide binding]; other site
228410000807	Walker A motif; other site
228410000808	ATP binding site [chemical binding]; other site
228410000809	Walker B motif; other site
228410000810	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
228410000811	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
228410000812	core domain interface [polypeptide binding]; other site
228410000813	delta subunit interface [polypeptide binding]; other site
228410000814	epsilon subunit interface [polypeptide binding]; other site
228410000815	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
228410000816	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
228410000817	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
228410000818	alpha subunit interaction interface [polypeptide binding]; other site
228410000819	Walker A motif; other site
228410000820	ATP binding site [chemical binding]; other site
228410000821	Walker B motif; other site
228410000822	inhibitor binding site; inhibition site
228410000823	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
228410000824	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
228410000825	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
228410000826	gamma subunit interface [polypeptide binding]; other site
228410000827	epsilon subunit interface [polypeptide binding]; other site
228410000828	LBP interface [polypeptide binding]; other site
228410000829	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
228410000830	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
228410000831	Substrate binding site; other site
228410000832	Mg++ binding site; other site
228410000833	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
228410000834	active site
228410000835	substrate binding site [chemical binding]; other site
228410000836	CoA binding site [chemical binding]; other site
228410000837	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
228410000838	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
228410000839	glutaminase active site [active]
228410000840	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
228410000841	dimer interface [polypeptide binding]; other site
228410000842	active site
228410000843	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
228410000844	dimer interface [polypeptide binding]; other site
228410000845	active site
228410000846	hypothetical protein; Validated; Region: PRK00110
228410000847	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
228410000848	active site
228410000849	putative DNA-binding cleft [nucleotide binding]; other site
228410000850	dimer interface [polypeptide binding]; other site
228410000851	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
228410000852	RuvA N terminal domain; Region: RuvA_N; pfam01330
228410000853	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
228410000854	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
228410000855	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410000856	Walker A motif; other site
228410000857	ATP binding site [chemical binding]; other site
228410000858	Walker B motif; other site
228410000859	arginine finger; other site
228410000860	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
228410000861	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
228410000862	active site
228410000863	TolQ protein; Region: tolQ; TIGR02796
228410000864	3 probable transmembrane helices predicted by TMHMM2.0
228410000865	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
228410000866	TolR protein; Region: tolR; TIGR02801
228410000867	1 probable transmembrane helix predicted by TMHMM2.0
228410000868	TolA protein; Region: tolA_full; TIGR02794
228410000869	TonB C terminal; Region: TonB_2; pfam13103
228410000870	1 probable transmembrane helix predicted by TMHMM2.0
228410000871	translocation protein TolB; Provisional; Region: tolB; PRK02889
228410000872	TolB amino-terminal domain; Region: TolB_N; pfam04052
228410000873	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410000874	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410000875	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410000876	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 at residue 23
228410000877	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
228410000878	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
228410000879	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
228410000880	ligand binding site [chemical binding]; other site
228410000881	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.972 at residue 22
228410000882	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
228410000883	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410000884	TPR motif; other site
228410000885	binding surface
228410000886	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 20
228410000887	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, gammaproteobacterial type; Region: rSAM_QueE_gams; TIGR04349
228410000888	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410000889	FeS/SAM binding site; other site
228410000890	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
228410000891	Ligand Binding Site [chemical binding]; other site
228410000892	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.951) with cleavage site probability 0.602 at residue 20
228410000893	Dihydroneopterin aldolase; Region: FolB; smart00905
228410000894	active site
228410000895	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
228410000896	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.644 at residue 23
228410000897	4 probable transmembrane helices predicted by TMHMM2.0
228410000898	UGMP family protein; Validated; Region: PRK09604
228410000899	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
228410000900	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
228410000901	Yqey-like protein; Region: YqeY; pfam09424
228410000902	DNA primase; Validated; Region: dnaG; PRK05667
228410000903	CHC2 zinc finger; Region: zf-CHC2; pfam01807
228410000904	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
228410000905	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
228410000906	active site
228410000907	metal binding site [ion binding]; metal-binding site
228410000908	interdomain interaction site; other site
228410000909	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
228410000910	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
228410000911	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
228410000912	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
228410000913	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
228410000914	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
228410000915	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410000916	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
228410000917	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410000918	DNA binding residues [nucleotide binding]
228410000919	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
228410000920	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
228410000921	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
228410000922	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
228410000923	active site
228410000924	metal binding site [ion binding]; metal-binding site
228410000925	interdomain interaction site; other site
228410000926	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
228410000927	active site
228410000928	DNA binding site [nucleotide binding]
228410000929	Int/Topo IB signature motif; other site
228410000930	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
228410000931	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
228410000932	catalytic residues [active]
228410000933	catalytic nucleophile [active]
228410000934	Recombinase; Region: Recombinase; pfam07508
228410000935	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
228410000936	ISNE1
228410000937	Winged helix-turn helix; Region: HTH_29; pfam13551
228410000938	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410000939	Homeodomain-like domain; Region: HTH_32; pfam13565
228410000940	Integrase core domain; Region: rve; pfam00665
228410000941	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410000942	Integrase core domain; Region: rve_3; pfam13683
228410000943	Sel1-like repeats; Region: SEL1; smart00671
228410000944	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
228410000945	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410000946	binding surface
228410000947	TPR motif; other site
228410000948	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410000949	binding surface
228410000950	TPR motif; other site
228410000951	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410000952	TPR motif; other site
228410000953	binding surface
228410000954	Sel1-like repeats; Region: SEL1; smart00671
228410000955	4 probable transmembrane helices predicted by TMHMM2.0
228410000956	Winged helix-turn helix; Region: HTH_29; pfam13551
228410000957	Integrase core domain; Region: rve; pfam00665
228410000958	Integrase core domain; Region: rve_3; pfam13683
228410000959	ISNE2
228410000960	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
228410000961	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
228410000962	Walker A motif; other site
228410000963	ATP binding site [chemical binding]; other site
228410000964	Walker B motif; other site
228410000965	2 probable transmembrane helices predicted by TMHMM2.0
228410000966	NE0247 and NE0250 are two parts of a pseudogene caused by the interruption of an IS element
228410000967	NE0247 and NE0250 are 2 parts of a dead gene due to IS element insertion;Lysine exporter protein (LYSE/YGGA)
228410000968	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.898 at residue 26
228410000969	3 probable transmembrane helices predicted by TMHMM2.0
228410000970	dead due to upsteam premature stop codoni in NE0248;probable ISRm2011-2 transposase protein, C-terminal portion
228410000971	dead due to premature stop codon, the second part of the gene is modeled as NE0248;possible transposase
228410000972	NE0247 and NE0250 are 2 parts of a dead gene due to IS element insertion;conserved hypothetical protein
228410000973	2 probable transmembrane helices predicted by TMHMM2.0
228410000974	Fic/DOC family; Region: Fic; pfam02661
228410000975	Fic family protein [Function unknown]; Region: COG3177
228410000976	ISNE3
228410000977	putative transposase OrfB; Reviewed; Region: PHA02517
228410000978	HTH-like domain; Region: HTH_21; pfam13276
228410000979	Integrase core domain; Region: rve; pfam00665
228410000980	Integrase core domain; Region: rve_3; pfam13683
228410000981	ISNE1
228410000982	Winged helix-turn helix; Region: HTH_29; pfam13551
228410000983	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410000984	Homeodomain-like domain; Region: HTH_32; pfam13565
228410000985	Integrase core domain; Region: rve; pfam00665
228410000986	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410000987	Integrase core domain; Region: rve_3; pfam13683
228410000988	1 probable transmembrane helix predicted by TMHMM2.0
228410000989	ISNE
228410000990	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
228410000991	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
228410000992	catalytic residues [active]
228410000993	catalytic nucleophile [active]
228410000994	Presynaptic Site I dimer interface [polypeptide binding]; other site
228410000995	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
228410000996	Synaptic Flat tetramer interface [polypeptide binding]; other site
228410000997	Synaptic Site I dimer interface [polypeptide binding]; other site
228410000998	DNA binding site [nucleotide binding]
228410000999	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
228410001000	DNA-binding interface [nucleotide binding]; DNA binding site
228410001001	Antirestriction protein (ArdA); Region: ArdA; pfam07275
228410001002	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
228410001003	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
228410001004	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
228410001005	dimerization interface [polypeptide binding]; other site
228410001006	putative DNA binding site [nucleotide binding]; other site
228410001007	putative Zn2+ binding site [ion binding]; other site
228410001008	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_3; cd08896
228410001009	putative hydrophobic ligand binding site [chemical binding]; other site
228410001010	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
228410001011	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
228410001012	dimer interface [polypeptide binding]; other site
228410001013	Protein of unknown function (DUF1428); Region: DUF1428; pfam07237
228410001014	ISNE1
228410001015	Winged helix-turn helix; Region: HTH_29; pfam13551
228410001016	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410001017	Homeodomain-like domain; Region: HTH_32; pfam13565
228410001018	Integrase core domain; Region: rve; pfam00665
228410001019	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410001020	Integrase core domain; Region: rve_3; pfam13683
228410001021	5' remnant of gene interrupted by an IS element;pseudogene
228410001022	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410001023	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410001024	ISNE5
228410001025	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410001026	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
228410001027	Cytochrome c553 [Energy production and conversion]; Region: COG2863
228410001028	Cytochrome c553 [Energy production and conversion]; Region: COG2863
228410001029	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 22
228410001030	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.892) with cleavage site probability 0.890 at residue 22
228410001031	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
228410001032	active site
228410001033	ribonuclease PH; Reviewed; Region: rph; PRK00173
228410001034	Ribonuclease PH; Region: RNase_PH_bact; cd11362
228410001035	hexamer interface [polypeptide binding]; other site
228410001036	active site
228410001037	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
228410001038	active site
228410001039	dimerization interface [polypeptide binding]; other site
228410001040	coproporphyrinogen III oxidase; Provisional; Region: PRK08898
228410001041	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410001042	FeS/SAM binding site; other site
228410001043	HemN C-terminal domain; Region: HemN_C; pfam06969
228410001044	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
228410001045	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
228410001046	Multicopper oxidase; Region: Cu-oxidase; pfam00394
228410001047	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
228410001048	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.987 at residue 27
228410001049	Copper resistance protein B precursor (CopB); Region: CopB; pfam05275
228410001050	E3 Ubiquitin ligase; Region: GIDE; pfam12483
228410001051	EF hand; Region: EF_hand_3; pfam13202
228410001052	2 probable transmembrane helices predicted by TMHMM2.0
228410001053	LemA family; Region: LemA; cl00742
228410001054	1 probable transmembrane helix predicted by TMHMM2.0
228410001055	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410001056	S-adenosylmethionine binding site [chemical binding]; other site
228410001057	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
228410001058	ThiS interaction site; other site
228410001059	putative active site [active]
228410001060	tetramer interface [polypeptide binding]; other site
228410001061	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
228410001062	thiS-thiF/thiG interaction site; other site
228410001063	MEKHLA domain; Region: MEKHLA; pfam08670
228410001064	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410001065	oligomeric interface; other site
228410001066	putative active site [active]
228410001067	homodimer interface [polypeptide binding]; other site
228410001068	ISNE2
228410001069	Winged helix-turn helix; Region: HTH_29; pfam13551
228410001070	Integrase core domain; Region: rve; pfam00665
228410001071	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410001072	Integrase core domain; Region: rve_3; pfam13683
228410001073	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
228410001074	NE0290 and NE0291 are 2 parts of a pseudogene caused by a frameshift
228410001075	NE0290 and NE0291 are 2 parts of a dead gene due to a frameshift;conserved hypothetical protein
228410001076	NE0290 and NE0291 are 2 parts of a dead gene due to a frameshift; transmembrane sensor
228410001077	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
228410001078	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
228410001079	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
228410001080	Cytochrome c; Region: Cytochrom_C; pfam00034
228410001081	High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672
228410001082	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.908 at residue 33
228410001083	8 probable transmembrane helices predicted by TMHMM2.0
228410001084	Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones]; Region: COG4067
228410001085	1 probable transmembrane helix predicted by TMHMM2.0
228410001086	Inactive transglutaminase fused to 7 transmembrane helices; Region: Transglut_i_TM; pfam14400
228410001087	7 transmembrane helices usually fused to an inactive transglutaminase; Region: 7TM_transglut; pfam14402
228410001088	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.313 at residue 35
228410001089	6 probable transmembrane helices predicted by TMHMM2.0
228410001090	alpha-L-glutamate ligase-related protein; Region: rimK_rel_E_lig; TIGR02291
228410001091	Sugar-transfer associated ATP-grasp; Region: ATPgrasp_ST; pfam14397
228410001092	phosphate acetyltransferase; Reviewed; Region: PRK05632
228410001093	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
228410001094	DRTGG domain; Region: DRTGG; pfam07085
228410001095	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
228410001096	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
228410001097	4 probable transmembrane helices predicted by TMHMM2.0
228410001098	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
228410001099	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
228410001100	COQ9; Region: COQ9; pfam08511
228410001101	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
228410001102	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
228410001103	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.930 at residue 22
228410001104	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
228410001105	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
228410001106	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
228410001107	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
228410001108	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.822) with cleavage site probability 0.429 at residue 16
228410001109	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
228410001110	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
228410001111	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
228410001112	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
228410001113	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
228410001114	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
228410001115	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
228410001116	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
228410001117	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
228410001118	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
228410001119	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12694
228410001120	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
228410001121	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
228410001122	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12699
228410001123	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
228410001124	1 probable transmembrane helix predicted by TMHMM2.0
228410001125	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
228410001126	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
228410001127	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 25
228410001128	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
228410001129	flagellar rod assembly protein/muramidase FlgJ; Region: flagell_FlgJ; TIGR02541
228410001130	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
228410001131	flagellar hook-associated protein FlgK; Region: flgK_ends; TIGR02492
228410001132	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
228410001133	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK07192
228410001134	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
228410001135	3 probable transmembrane helices predicted by TMHMM2.0
228410001136	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.953) with cleavage site probability 0.491 at residue 21
228410001137	Protein of unknown function DUF89; Region: DUF89; pfam01937
228410001138	Bacterial transcriptional activator domain; Region: BTAD; smart01043
228410001139	Predicted transcriptional regulator [Transcription]; Region: COG2932
228410001140	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
228410001141	Catalytic site [active]
228410001142	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
228410001143	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
228410001144	Coenzyme A binding pocket [chemical binding]; other site
228410001145	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410001146	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410001147	N-terminal plug; other site
228410001148	ligand-binding site [chemical binding]; other site
228410001149	oxidative damage protection protein; Provisional; Region: PRK05408
228410001150	polyphosphate kinase; Provisional; Region: PRK05443
228410001151	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
228410001152	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
228410001153	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
228410001154	putative domain interface [polypeptide binding]; other site
228410001155	putative active site [active]
228410001156	catalytic site [active]
228410001157	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
228410001158	putative domain interface [polypeptide binding]; other site
228410001159	putative active site [active]
228410001160	catalytic site [active]
228410001161	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
228410001162	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
228410001163	intersubunit interface [polypeptide binding]; other site
228410001164	active site
228410001165	zinc binding site [ion binding]; other site
228410001166	Na+ binding site [ion binding]; other site
228410001167	pyruvate kinase; Provisional; Region: PRK05826
228410001168	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
228410001169	domain interfaces; other site
228410001170	active site
228410001171	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.985) with cleavage site probability 0.974 at residue 19
228410001172	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
228410001173	Phosphoglycerate kinase; Region: PGK; pfam00162
228410001174	substrate binding site [chemical binding]; other site
228410001175	hinge regions; other site
228410001176	ADP binding site [chemical binding]; other site
228410001177	catalytic site [active]
228410001178	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
228410001179	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
228410001180	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
228410001181	transketolase; Reviewed; Region: PRK12753
228410001182	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
228410001183	TPP-binding site [chemical binding]; other site
228410001184	dimer interface [polypeptide binding]; other site
228410001185	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
228410001186	PYR/PP interface [polypeptide binding]; other site
228410001187	dimer interface [polypeptide binding]; other site
228410001188	TPP binding site [chemical binding]; other site
228410001189	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
228410001190	hopanoid biosynthesis associated radical SAM protein HpnH; Region: HpnH; TIGR03470
228410001191	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410001192	FeS/SAM binding site; other site
228410001193	Domain of unknown function (DUF3463); Region: DUF3463; pfam11946
228410001194	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
228410001195	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
228410001196	active site
228410001197	4 probable transmembrane helices predicted by TMHMM2.0
228410001198	hopanoid biosynthesis associated membrane protein HpnM; Region: HpnM; TIGR03481
228410001199	DNA gyrase subunit A; Validated; Region: PRK05560
228410001200	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
228410001201	CAP-like domain; other site
228410001202	active site
228410001203	primary dimer interface [polypeptide binding]; other site
228410001204	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
228410001205	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
228410001206	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
228410001207	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
228410001208	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
228410001209	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
228410001210	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
228410001211	homodimer interface [polypeptide binding]; other site
228410001212	substrate-cofactor binding pocket; other site
228410001213	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410001214	catalytic residue [active]
228410001215	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
228410001216	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
228410001217	putative ligand binding site [chemical binding]; other site
228410001218	putative NAD binding site [chemical binding]; other site
228410001219	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
228410001220	L-serine binding site [chemical binding]; other site
228410001221	ACT domain interface; other site
228410001222	Chorismate mutase type II; Region: CM_2; pfam01817
228410001223	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
228410001224	Prephenate dehydratase; Region: PDT; pfam00800
228410001225	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
228410001226	putative L-Phe binding site [chemical binding]; other site
228410001227	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
228410001228	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
228410001229	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410001230	homodimer interface [polypeptide binding]; other site
228410001231	catalytic residue [active]
228410001232	cyclohexadienyl dehydrogenase; Validated; Region: PRK07502
228410001233	prephenate dehydrogenase; Validated; Region: PRK08507
228410001234	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.625) with cleavage site probability 0.361 at residue 25
228410001235	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
228410001236	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
228410001237	active site
228410001238	DNA binding site [nucleotide binding]
228410001239	Int/Topo IB signature motif; other site
228410001240	Protein of unknown function, DUF484; Region: DUF484; cl17449
228410001241	Winged helix-turn helix; Region: HTH_29; pfam13551
228410001242	Integrase core domain; Region: rve; pfam00665
228410001243	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410001244	Integrase core domain; Region: rve_3; pfam13683
228410001245	ISNE2
228410001246	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410001247	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410001248	ISNE5
228410001249	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410001250	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
228410001251	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
228410001252	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
228410001253	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410001254	ATP binding site [chemical binding]; other site
228410001255	Mg2+ binding site [ion binding]; other site
228410001256	G-X-G motif; other site
228410001257	2 probable transmembrane helices predicted by TMHMM2.0
228410001258	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
228410001259	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410001260	active site
228410001261	phosphorylation site [posttranslational modification]
228410001262	intermolecular recognition site; other site
228410001263	dimerization interface [polypeptide binding]; other site
228410001264	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
228410001265	DNA binding site [nucleotide binding]
228410001266	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
228410001267	12 probable transmembrane helices predicted by TMHMM2.0
228410001268	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.746) with cleavage site probability 0.450 at residue 31
228410001269	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410001270	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410001271	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410001272	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.488 at residue 37
228410001273	1 probable transmembrane helix predicted by TMHMM2.0
228410001274	spermidine synthase; Provisional; Region: PRK00811
228410001275	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410001276	S-adenosylmethionine binding site [chemical binding]; other site
228410001277	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; pfam02675
228410001278	ribonuclease R; Region: RNase_R; TIGR02063
228410001279	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
228410001280	RNB domain; Region: RNB; pfam00773
228410001281	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
228410001282	RNA binding site [nucleotide binding]; other site
228410001283	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
228410001284	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
228410001285	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
228410001286	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
228410001287	TolR protein; Region: tolR; TIGR02801
228410001288	1 probable transmembrane helix predicted by TMHMM2.0
228410001289	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
228410001290	3 probable transmembrane helices predicted by TMHMM2.0
228410001291	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
228410001292	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
228410001293	1 probable transmembrane helix predicted by TMHMM2.0
228410001294	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 at residue 27
228410001295	ribonuclease G; Provisional; Region: PRK11712
228410001296	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
228410001297	homodimer interface [polypeptide binding]; other site
228410001298	oligonucleotide binding site [chemical binding]; other site
228410001299	Maf-like protein; Region: Maf; pfam02545
228410001300	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
228410001301	active site
228410001302	dimer interface [polypeptide binding]; other site
228410001303	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
228410001304	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
228410001305	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
228410001306	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
228410001307	active site
228410001308	(T/H)XGH motif; other site
228410001309	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
228410001310	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
228410001311	E3 interaction surface; other site
228410001312	lipoyl attachment site [posttranslational modification]; other site
228410001313	e3 binding domain; Region: E3_binding; pfam02817
228410001314	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
228410001315	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
228410001316	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
228410001317	dimer interface [polypeptide binding]; other site
228410001318	TPP-binding site [chemical binding]; other site
228410001319	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14189
228410001320	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
228410001321	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
228410001322	homodimer interface [polypeptide binding]; other site
228410001323	NADP binding site [chemical binding]; other site
228410001324	substrate binding site [chemical binding]; other site
228410001325	2 probable transmembrane helices predicted by TMHMM2.0
228410001326	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
228410001327	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
228410001328	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
228410001329	active site
228410001330	HIGH motif; other site
228410001331	nucleotide binding site [chemical binding]; other site
228410001332	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
228410001333	KMSK motif region; other site
228410001334	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
228410001335	tRNA binding surface [nucleotide binding]; other site
228410001336	anticodon binding site; other site
228410001337	Sporulation related domain; Region: SPOR; pfam05036
228410001338	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.915) with cleavage site probability 0.436 at residue 36
228410001339	1 probable transmembrane helix predicted by TMHMM2.0
228410001340	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
228410001341	catalytic residues [active]
228410001342	hinge region; other site
228410001343	alpha helical domain; other site
228410001344	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.941 at residue 27
228410001345	1 probable transmembrane helix predicted by TMHMM2.0
228410001346	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
228410001347	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
228410001348	Zn2+ binding site [ion binding]; other site
228410001349	Mg2+ binding site [ion binding]; other site
228410001350	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
228410001351	synthetase active site [active]
228410001352	NTP binding site [chemical binding]; other site
228410001353	metal binding site [ion binding]; metal-binding site
228410001354	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
228410001355	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
228410001356	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
228410001357	2 probable transmembrane helices predicted by TMHMM2.0
228410001358	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
228410001359	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.645) with cleavage site probability 0.484 at residue 25
228410001360	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_like_1; cd08581
228410001361	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
228410001362	putative active site [active]
228410001363	catalytic site [active]
228410001364	putative metal binding site [ion binding]; other site
228410001365	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.683 at residue 33
228410001366	2 probable transmembrane helices predicted by TMHMM2.0
228410001367	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.933 at residue 26
228410001368	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
228410001369	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410001370	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
228410001371	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410001372	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.727) with cleavage site probability 0.292 at residue 25
228410001373	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
228410001374	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.986 at residue 32
228410001375	12 probable transmembrane helices predicted by TMHMM2.0
228410001376	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
228410001377	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410001378	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
228410001379	Walker A/P-loop; other site
228410001380	ATP binding site [chemical binding]; other site
228410001381	Q-loop/lid; other site
228410001382	ABC transporter signature motif; other site
228410001383	Walker B; other site
228410001384	D-loop; other site
228410001385	H-loop/switch region; other site
228410001386	5 probable transmembrane helices predicted by TMHMM2.0
228410001387	putative PEP-CTERM system histidine kinase; Region: PEP_his_kin; TIGR02916
228410001388	GAF domain; Region: GAF_3; pfam13492
228410001389	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
228410001390	dimer interface [polypeptide binding]; other site
228410001391	phosphorylation site [posttranslational modification]
228410001392	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410001393	ATP binding site [chemical binding]; other site
228410001394	Mg2+ binding site [ion binding]; other site
228410001395	G-X-G motif; other site
228410001396	9 probable transmembrane helices predicted by TMHMM2.0
228410001397	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.981 at residue 45
228410001398	sugar transferase, PEP-CTERM system associated; Region: EpsB_2; TIGR03013
228410001399	Bacterial sugar transferase; Region: Bac_transf; pfam02397
228410001400	5 probable transmembrane helices predicted by TMHMM2.0
228410001401	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
228410001402	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
228410001403	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
228410001404	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
228410001405	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
228410001406	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
228410001407	EamA-like transporter family; Region: EamA; pfam00892
228410001408	EamA-like transporter family; Region: EamA; pfam00892
228410001409	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.749) with cleavage site probability 0.317 at residue 40
228410001410	10 probable transmembrane helices predicted by TMHMM2.0
228410001411	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
228410001412	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
228410001413	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410001414	ATP binding site [chemical binding]; other site
228410001415	putative Mg++ binding site [ion binding]; other site
228410001416	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
228410001417	Divergent AAA domain; Region: AAA_4; pfam04326
228410001418	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
228410001419	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
228410001420	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
228410001421	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
228410001422	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
228410001423	HsdM N-terminal domain; Region: HsdM_N; pfam12161
228410001424	HsdM N-terminal domain; Region: HsdM_N; pfam12161
228410001425	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
228410001426	Methyltransferase domain; Region: Methyltransf_26; pfam13659
228410001427	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
228410001428	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
228410001429	trmE is a tRNA modification GTPase; Region: trmE; cd04164
228410001430	G1 box; other site
228410001431	GTP/Mg2+ binding site [chemical binding]; other site
228410001432	Switch I region; other site
228410001433	G2 box; other site
228410001434	Switch II region; other site
228410001435	G3 box; other site
228410001436	G4 box; other site
228410001437	G5 box; other site
228410001438	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
228410001439	membrane protein insertase; Provisional; Region: PRK01318
228410001440	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
228410001441	4 probable transmembrane helices predicted by TMHMM2.0
228410001442	Haemolytic domain; Region: Haemolytic; pfam01809
228410001443	Ribonuclease P; Region: Ribonuclease_P; pfam00825
228410001444	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
228410001445	3 probable transmembrane helices predicted by TMHMM2.0
228410001446	Protein of unknown function (DUF2905); Region: DUF2905; pfam11146
228410001447	2 probable transmembrane helices predicted by TMHMM2.0
228410001448	pyrroline-5-carboxylate reductase; Region: PLN02688
228410001449	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
228410001450	YGGT family; Region: YGGT; pfam02325
228410001451	YGGT family; Region: YGGT; pfam02325
228410001452	4 probable transmembrane helices predicted by TMHMM2.0
228410001453	Uncharacterized ACR, YggU family COG1872; Region: DUF167; cl00811
228410001454	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
228410001455	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
228410001456	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK12490
228410001457	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
228410001458	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
228410001459	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
228410001460	elongation factor Tu; Reviewed; Region: PRK00049
228410001461	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
228410001462	G1 box; other site
228410001463	GEF interaction site [polypeptide binding]; other site
228410001464	GTP/Mg2+ binding site [chemical binding]; other site
228410001465	Switch I region; other site
228410001466	G2 box; other site
228410001467	G3 box; other site
228410001468	Switch II region; other site
228410001469	G4 box; other site
228410001470	G5 box; other site
228410001471	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
228410001472	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
228410001473	Antibiotic Binding Site [chemical binding]; other site
228410001474	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
228410001475	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
228410001476	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
228410001477	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
228410001478	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
228410001479	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
228410001480	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
228410001481	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
228410001482	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
228410001483	protein-rRNA interface [nucleotide binding]; other site
228410001484	putative translocon binding site; other site
228410001485	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
228410001486	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
228410001487	G-X-X-G motif; other site
228410001488	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
228410001489	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
228410001490	23S rRNA interface [nucleotide binding]; other site
228410001491	5S rRNA interface [nucleotide binding]; other site
228410001492	putative antibiotic binding site [chemical binding]; other site
228410001493	L25 interface [polypeptide binding]; other site
228410001494	L27 interface [polypeptide binding]; other site
228410001495	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
228410001496	23S rRNA interface [nucleotide binding]; other site
228410001497	putative translocon interaction site; other site
228410001498	signal recognition particle (SRP54) interaction site; other site
228410001499	L23 interface [polypeptide binding]; other site
228410001500	trigger factor interaction site; other site
228410001501	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
228410001502	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
228410001503	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
228410001504	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
228410001505	RNA binding site [nucleotide binding]; other site
228410001506	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
228410001507	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
228410001508	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
228410001509	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
228410001510	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
228410001511	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
228410001512	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
228410001513	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
228410001514	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
228410001515	5S rRNA interface [nucleotide binding]; other site
228410001516	L27 interface [polypeptide binding]; other site
228410001517	23S rRNA interface [nucleotide binding]; other site
228410001518	L5 interface [polypeptide binding]; other site
228410001519	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
228410001520	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
228410001521	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
228410001522	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
228410001523	23S rRNA binding site [nucleotide binding]; other site
228410001524	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
228410001525	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
228410001526	SecY translocase; Region: SecY; pfam00344
228410001527	10 probable transmembrane helices predicted by TMHMM2.0
228410001528	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
228410001529	rRNA binding site [nucleotide binding]; other site
228410001530	predicted 30S ribosome binding site; other site
228410001531	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
228410001532	30S ribosomal protein S13; Region: bact_S13; TIGR03631
228410001533	30S ribosomal protein S11; Validated; Region: PRK05309
228410001534	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
228410001535	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
228410001536	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
228410001537	RNA binding surface [nucleotide binding]; other site
228410001538	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
228410001539	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
228410001540	alphaNTD homodimer interface [polypeptide binding]; other site
228410001541	alphaNTD - beta interaction site [polypeptide binding]; other site
228410001542	alphaNTD - beta' interaction site [polypeptide binding]; other site
228410001543	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
228410001544	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
228410001545	hypothetical protein; Validated; Region: PRK01777
228410001546	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
228410001547	putative coenzyme Q binding site [chemical binding]; other site
228410001548	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
228410001549	SmpB-tmRNA interface; other site
228410001550	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
228410001551	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
228410001552	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.893) with cleavage site probability 0.420 at residue 46
228410001553	8 probable transmembrane helices predicted by TMHMM2.0
228410001554	RDD family; Region: RDD; pfam06271
228410001555	3 probable transmembrane helices predicted by TMHMM2.0
228410001556	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14969
228410001557	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410001558	Walker A motif; other site
228410001559	ATP binding site [chemical binding]; other site
228410001560	Walker B motif; other site
228410001561	arginine finger; other site
228410001562	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
228410001563	hypothetical protein; Validated; Region: PRK00153
228410001564	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
228410001565	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
228410001566	RNA binding surface [nucleotide binding]; other site
228410001567	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
228410001568	probable active site [active]
228410001569	Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890
228410001570	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410001571	S-adenosylmethionine binding site [chemical binding]; other site
228410001572	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
228410001573	nucleoside/Zn binding site; other site
228410001574	dimer interface [polypeptide binding]; other site
228410001575	catalytic motif [active]
228410001576	malate dehydrogenase; Provisional; Region: PRK13529
228410001577	Malic enzyme, N-terminal domain; Region: malic; pfam00390
228410001578	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
228410001579	NAD(P) binding site [chemical binding]; other site
228410001580	Domain of unknown function (DUF4072); Region: DUF4072; pfam13284
228410001581	phosphoserine phosphatase SerB; Region: serB; TIGR00338
228410001582	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410001583	motif II; other site
228410001584	HDOD domain; Region: HDOD; pfam08668
228410001585	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
228410001586	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
228410001587	metal binding site [ion binding]; metal-binding site
228410001588	active site
228410001589	I-site; other site
228410001590	multifunctional aminopeptidase A; Provisional; Region: PRK00913
228410001591	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
228410001592	interface (dimer of trimers) [polypeptide binding]; other site
228410001593	Substrate-binding/catalytic site; other site
228410001594	Zn-binding sites [ion binding]; other site
228410001595	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; pfam04364
228410001596	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
228410001597	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
228410001598	HIGH motif; other site
228410001599	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
228410001600	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
228410001601	active site
228410001602	KMSKS motif; other site
228410001603	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
228410001604	tRNA binding surface [nucleotide binding]; other site
228410001605	anticodon binding site; other site
228410001606	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
228410001607	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
228410001608	substrate binding site [chemical binding]; other site
228410001609	active site
228410001610	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
228410001611	dimer interface [polypeptide binding]; other site
228410001612	Methyladenine glycosylase; Region: Adenine_glyco; cl01059
228410001613	Ammonium Transporter Family; Region: Ammonium_transp; cl03012
228410001614	12 probable transmembrane helices predicted by TMHMM2.0
228410001615	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.728 at residue 25
228410001616	glutamate racemase; Provisional; Region: PRK00865
228410001617	integron integrase; Region: integrase_gron; TIGR02249
228410001618	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
228410001619	Int/Topo IB signature motif; other site
228410001620	ISNE3
228410001621	putative transposase OrfB; Reviewed; Region: PHA02517
228410001622	HTH-like domain; Region: HTH_21; pfam13276
228410001623	Integrase core domain; Region: rve; pfam00665
228410001624	Integrase core domain; Region: rve_3; pfam13683
228410001625	5' remnant of gene interrupted by an IS element;Patatin
228410001626	ISNE2
228410001627	Winged helix-turn helix; Region: HTH_29; pfam13551
228410001628	Integrase core domain; Region: rve; pfam00665
228410001629	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410001630	Integrase core domain; Region: rve_3; pfam13683
228410001631	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
228410001632	Putative serine esterase (DUF676); Region: DUF676; pfam05057
228410001633	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
228410001634	1 probable transmembrane helix predicted by TMHMM2.0
228410001635	Uncharacterized conserved protein [Function unknown]; Region: COG5316
228410001636	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
228410001637	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.608) with cleavage site probability 0.344 at residue 24
228410001638	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
228410001639	6 probable transmembrane helices predicted by TMHMM2.0
228410001640	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.859) with cleavage site probability 0.607 at residue 35
228410001641	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
228410001642	2 probable transmembrane helices predicted by TMHMM2.0
228410001643	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
228410001644	5 probable transmembrane helices predicted by TMHMM2.0
228410001645	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 42
228410001646	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
228410001647	1 probable transmembrane helix predicted by TMHMM2.0
228410001648	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.990 at residue 23
228410001649	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
228410001650	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
228410001651	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
228410001652	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
228410001653	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07718
228410001654	1 probable transmembrane helix predicted by TMHMM2.0
228410001655	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
228410001656	putative homodimer interface [polypeptide binding]; other site
228410001657	putative active site pocket [active]
228410001658	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
228410001659	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
228410001660	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.798) with cleavage site probability 0.271 at residue 46
228410001661	8 probable transmembrane helices predicted by TMHMM2.0
228410001662	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
228410001663	transcriptional activator RfaH; Region: RfaH; TIGR01955
228410001664	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
228410001665	heterodimer interface [polypeptide binding]; other site
228410001666	homodimer interface [polypeptide binding]; other site
228410001667	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
228410001668	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
228410001669	NAD binding site [chemical binding]; other site
228410001670	substrate binding site [chemical binding]; other site
228410001671	homodimer interface [polypeptide binding]; other site
228410001672	active site
228410001673	3' remnant of gene;conserved hypothetical protein
228410001674	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
228410001675	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
228410001676	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
228410001677	6 probable transmembrane helices predicted by TMHMM2.0
228410001678	AAA domain; Region: AAA_14; pfam13173
228410001679	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
228410001680	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
228410001681	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
228410001682	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410001683	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410001684	Walker A/P-loop; other site
228410001685	ATP binding site [chemical binding]; other site
228410001686	Q-loop/lid; other site
228410001687	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410001688	ABC transporter signature motif; other site
228410001689	Walker B; other site
228410001690	D-loop; other site
228410001691	ABC transporter; Region: ABC_tran_2; pfam12848
228410001692	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410001693	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
228410001694	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410001695	oligomeric interface; other site
228410001696	putative active site [active]
228410001697	homodimer interface [polypeptide binding]; other site
228410001698	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
228410001699	addiction module antidote protein, HigA family; Region: antidote_HigA; TIGR02607
228410001700	sequence-specific DNA binding site [nucleotide binding]; other site
228410001701	salt bridge; other site
228410001702	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
228410001703	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
228410001704	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
228410001705	Walker A/P-loop; other site
228410001706	ATP binding site [chemical binding]; other site
228410001707	Q-loop/lid; other site
228410001708	ABC transporter signature motif; other site
228410001709	Walker B; other site
228410001710	D-loop; other site
228410001711	H-loop/switch region; other site
228410001712	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
228410001713	putative carbohydrate binding site [chemical binding]; other site
228410001714	Methyltransferase domain; Region: Methyltransf_23; pfam13489
228410001715	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410001716	S-adenosylmethionine binding site [chemical binding]; other site
228410001717	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
228410001718	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
228410001719	putative homodimer interface [polypeptide binding]; other site
228410001720	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
228410001721	putative ligand binding site [chemical binding]; other site
228410001722	putative catalytic site [active]
228410001723	1 probable transmembrane helix predicted by TMHMM2.0
228410001724	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
228410001725	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
228410001726	active site
228410001727	homodimer interface [polypeptide binding]; other site
228410001728	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
228410001729	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
228410001730	AIPR protein; Region: AIPR; pfam10592
228410001731	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
228410001732	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410001733	sequence-specific DNA binding site [nucleotide binding]; other site
228410001734	salt bridge; other site
228410001735	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
228410001736	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
228410001737	Helix-turn-helix domain; Region: HTH_17; pfam12728
228410001738	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
228410001739	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410001740	oligomeric interface; other site
228410001741	putative active site [active]
228410001742	homodimer interface [polypeptide binding]; other site
228410001743	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
228410001744	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
228410001745	Probable Catalytic site; other site
228410001746	metal-binding site
228410001747	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
228410001748	UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs; Region: UDP_G4E_4_SDR_e; cd05232
228410001749	putative NAD(P) binding site [chemical binding]; other site
228410001750	active site
228410001751	putative substrate binding site [chemical binding]; other site
228410001752	Bacterial sugar transferase; Region: Bac_transf; pfam02397
228410001753	1 probable transmembrane helix predicted by TMHMM2.0
228410001754	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
228410001755	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
228410001756	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
228410001757	NAD(P) binding site [chemical binding]; other site
228410001758	homodimer interface [polypeptide binding]; other site
228410001759	substrate binding site [chemical binding]; other site
228410001760	active site
228410001761	3 probable transmembrane helices predicted by TMHMM2.0
228410001762	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.539 at residue 22
228410001763	glutamine synthetase; Provisional; Region: glnA; PRK09469
228410001764	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
228410001765	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
228410001766	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
228410001767	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
228410001768	RNA binding surface [nucleotide binding]; other site
228410001769	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
228410001770	active site
228410001771	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
228410001772	recombination associated protein; Reviewed; Region: rdgC; PRK00321
228410001773	Protein of unknown function (DUF1292); Region: DUF1292; pfam06949
228410001774	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.978) with cleavage site probability 0.637 at residue 20
228410001775	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
228410001776	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
228410001777	Cu(I) binding site [ion binding]; other site
228410001778	1 probable transmembrane helix predicted by TMHMM2.0
228410001779	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.974 at residue 28
228410001780	1 probable transmembrane helix predicted by TMHMM2.0
228410001781	Putative exonuclease, RdgC; Region: RdgC; cl01122
228410001782	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.961 at residue 21
228410001783	amino acid transporter; Region: 2A0306; TIGR00909
228410001784	13 probable transmembrane helices predicted by TMHMM2.0
228410001785	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
228410001786	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410001787	active site
228410001788	phosphorylation site [posttranslational modification]
228410001789	intermolecular recognition site; other site
228410001790	dimerization interface [polypeptide binding]; other site
228410001791	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
228410001792	DNA binding site [nucleotide binding]
228410001793	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
228410001794	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410001795	dimerization interface [polypeptide binding]; other site
228410001796	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410001797	dimer interface [polypeptide binding]; other site
228410001798	phosphorylation site [posttranslational modification]
228410001799	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410001800	ATP binding site [chemical binding]; other site
228410001801	Mg2+ binding site [ion binding]; other site
228410001802	G-X-G motif; other site
228410001803	2 probable transmembrane helices predicted by TMHMM2.0
228410001804	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.969) with cleavage site probability 0.721 at residue 30
228410001805	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
228410001806	dimerization domain [polypeptide binding]; other site
228410001807	dimer interface [polypeptide binding]; other site
228410001808	catalytic residues [active]
228410001809	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.933 at residue 22
228410001810	Winged helix-turn helix; Region: HTH_29; pfam13551
228410001811	Integrase core domain; Region: rve; pfam00665
228410001812	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410001813	Integrase core domain; Region: rve_3; pfam13683
228410001814	ISNE2
228410001815	ISNE4
228410001816	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410001817	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410001818	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410001819	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 22
228410001820	fructose-1,6-bisphosphatase family protein; Region: PLN02628
228410001821	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
228410001822	AMP binding site [chemical binding]; other site
228410001823	metal binding site [ion binding]; metal-binding site
228410001824	active site
228410001825	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
228410001826	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
228410001827	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
228410001828	putative dimer interface [polypeptide binding]; other site
228410001829	N-terminal domain interface [polypeptide binding]; other site
228410001830	putative substrate binding pocket (H-site) [chemical binding]; other site
228410001831	DoxX; Region: DoxX; pfam07681
228410001832	FOG: CBS domain [General function prediction only]; Region: COG0517
228410001833	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
228410001834	FOG: CBS domain [General function prediction only]; Region: COG0517
228410001835	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
228410001836	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; pfam01985
228410001837	FtsJ-like methyltransferase; Region: FtsJ; cl17430
228410001838	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
228410001839	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
228410001840	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410001841	Walker A motif; other site
228410001842	ATP binding site [chemical binding]; other site
228410001843	Walker B motif; other site
228410001844	arginine finger; other site
228410001845	Peptidase family M41; Region: Peptidase_M41; pfam01434
228410001846	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.971) with cleavage site probability 0.467 at residue 29
228410001847	2 probable transmembrane helices predicted by TMHMM2.0
228410001848	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
228410001849	dihydropteroate synthase; Region: DHPS; TIGR01496
228410001850	substrate binding pocket [chemical binding]; other site
228410001851	dimer interface [polypeptide binding]; other site
228410001852	inhibitor binding site; inhibition site
228410001853	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
228410001854	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
228410001855	active site
228410001856	substrate binding site [chemical binding]; other site
228410001857	metal binding site [ion binding]; metal-binding site
228410001858	phosphate binding protein; Region: ptsS_2; TIGR02136
228410001859	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.963 at residue 32
228410001860	1 probable transmembrane helix predicted by TMHMM2.0
228410001861	siroheme synthase; Provisional; Region: cysG; PRK10637
228410001862	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
228410001863	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
228410001864	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
228410001865	active site
228410001866	SAM binding site [chemical binding]; other site
228410001867	homodimer interface [polypeptide binding]; other site
228410001868	RNA polymerase sigma factor; Reviewed; Region: PRK12523
228410001869	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410001870	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410001871	DNA binding residues [nucleotide binding]
228410001872	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410001873	FecR protein; Region: FecR; pfam04773
228410001874	1 probable transmembrane helix predicted by TMHMM2.0
228410001875	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410001876	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410001877	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410001878	N-terminal plug; other site
228410001879	ligand-binding site [chemical binding]; other site
228410001880	1 probable transmembrane helix predicted by TMHMM2.0
228410001881	BNR repeat-like domain; Region: BNR_2; pfam13088
228410001882	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.997 at residue 28
228410001883	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
228410001884	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
228410001885	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
228410001886	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.931) with cleavage site probability 0.486 at residue 35
228410001887	4 probable transmembrane helices predicted by TMHMM2.0
228410001888	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
228410001889	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.987) with cleavage site probability 0.974 at residue 23
228410001890	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410001891	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410001892	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
228410001893	11 probable transmembrane helices predicted by TMHMM2.0
228410001894	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
228410001895	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410001896	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410001897	DNA binding residues [nucleotide binding]
228410001898	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410001899	FecR protein; Region: FecR; pfam04773
228410001900	1 probable transmembrane helix predicted by TMHMM2.0
228410001901	HupE / UreJ protein; Region: HupE_UreJ_2; pfam13795
228410001902	7 probable transmembrane helices predicted by TMHMM2.0
228410001903	1 probable transmembrane helix predicted by TMHMM2.0
228410001904	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410001905	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410001906	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410001907	N-terminal plug; other site
228410001908	ligand-binding site [chemical binding]; other site
228410001909	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.968 at residue 20
228410001910	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
228410001911	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410001912	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410001913	DNA binding residues [nucleotide binding]
228410001914	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410001915	FecR protein; Region: FecR; pfam04773
228410001916	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410001917	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410001918	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410001919	N-terminal plug; other site
228410001920	ligand-binding site [chemical binding]; other site
228410001921	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 at residue 21
228410001922	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
228410001923	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
228410001924	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
228410001925	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
228410001926	4 probable transmembrane helices predicted by TMHMM2.0
228410001927	Predicted transcriptional regulator [Transcription]; Region: COG3905
228410001928	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
228410001929	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410001930	oligomeric interface; other site
228410001931	putative active site [active]
228410001932	homodimer interface [polypeptide binding]; other site
228410001933	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
228410001934	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410001935	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410001936	DNA binding residues [nucleotide binding]
228410001937	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410001938	FecR protein; Region: FecR; pfam04773
228410001939	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410001940	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410001941	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410001942	N-terminal plug; other site
228410001943	ligand-binding site [chemical binding]; other site
228410001944	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.984 at residue 22
228410001945	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
228410001946	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410001947	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410001948	DNA binding residues [nucleotide binding]
228410001949	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410001950	FecR protein; Region: FecR; pfam04773
228410001951	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410001952	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410001953	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410001954	N-terminal plug; other site
228410001955	ligand-binding site [chemical binding]; other site
228410001956	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.995 at residue 29
228410001957	ISNE4
228410001958	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410001959	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410001960	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410001961	ISNE2
228410001962	Winged helix-turn helix; Region: HTH_29; pfam13551
228410001963	Integrase core domain; Region: rve; pfam00665
228410001964	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410001965	Integrase core domain; Region: rve_3; pfam13683
228410001966	The 5' end of the coding region and promoter have been destroyed by IS elements;conserved hypothetical protein
228410001967	4 probable transmembrane helices predicted by TMHMM2.0
228410001968	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
228410001969	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
228410001970	Uncharacterized conserved protein [Function unknown]; Region: COG3391
228410001971	1 probable transmembrane helix predicted by TMHMM2.0
228410001972	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.413 at residue 27
228410001973	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
228410001974	Response regulator receiver domain; Region: Response_reg; pfam00072
228410001975	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410001976	active site
228410001977	phosphorylation site [posttranslational modification]
228410001978	intermolecular recognition site; other site
228410001979	dimerization interface [polypeptide binding]; other site
228410001980	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410001981	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
228410001982	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
228410001983	folate binding site [chemical binding]; other site
228410001984	NADP+ binding site [chemical binding]; other site
228410001985	thymidylate synthase; Reviewed; Region: thyA; PRK01827
228410001986	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
228410001987	dimerization interface [polypeptide binding]; other site
228410001988	active site
228410001989	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
228410001990	interface (dimer of trimers) [polypeptide binding]; other site
228410001991	Substrate-binding/catalytic site; other site
228410001992	Zn-binding sites [ion binding]; other site
228410001993	Domain of unknown function (DUF4389); Region: DUF4389; pfam14333
228410001994	1 probable transmembrane helix predicted by TMHMM2.0
228410001995	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
228410001996	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.983 at residue 25
228410001997	transcriptional regulator CysB-like protein; Reviewed; Region: PRK12683
228410001998	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
228410001999	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
228410002000	putative substrate binding site [chemical binding]; other site
228410002001	dimerization interface [polypeptide binding]; other site
228410002002	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
228410002003	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
228410002004	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
228410002005	catalytic residue [active]
228410002006	serine O-acetyltransferase; Region: cysE; TIGR01172
228410002007	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
228410002008	trimer interface [polypeptide binding]; other site
228410002009	active site
228410002010	substrate binding site [chemical binding]; other site
228410002011	CoA binding site [chemical binding]; other site
228410002012	ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118
228410002013	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
228410002014	Walker A/P-loop; other site
228410002015	ATP binding site [chemical binding]; other site
228410002016	Q-loop/lid; other site
228410002017	ABC transporter signature motif; other site
228410002018	Walker B; other site
228410002019	D-loop; other site
228410002020	H-loop/switch region; other site
228410002021	TOBE-like domain; Region: TOBE_3; pfam12857
228410002022	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410002023	dimer interface [polypeptide binding]; other site
228410002024	conserved gate region; other site
228410002025	putative PBP binding loops; other site
228410002026	ABC-ATPase subunit interface; other site
228410002027	5 probable transmembrane helices predicted by TMHMM2.0
228410002028	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
228410002029	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410002030	dimer interface [polypeptide binding]; other site
228410002031	conserved gate region; other site
228410002032	putative PBP binding loops; other site
228410002033	ABC-ATPase subunit interface; other site
228410002034	7 probable transmembrane helices predicted by TMHMM2.0
228410002035	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.831) with cleavage site probability 0.762 at residue 40
228410002036	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410002037	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410002038	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; cl01811
228410002039	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
228410002040	substrate binding pocket [chemical binding]; other site
228410002041	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
228410002042	membrane-bound complex binding site; other site
228410002043	hinge residues; other site
228410002044	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.971 at residue 25
228410002045	1 probable transmembrane helix predicted by TMHMM2.0
228410002046	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
228410002047	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.997 at residue 24
228410002048	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
228410002049	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410002050	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410002051	DNA binding residues [nucleotide binding]
228410002052	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
228410002053	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
228410002054	catalytic triad [active]
228410002055	Protein of unknown function (DUF2868); Region: DUF2868; pfam11067
228410002056	4 probable transmembrane helices predicted by TMHMM2.0
228410002057	50S ribosome-binding GTPase; Region: MMR_HSR1; pfam01926
228410002058	G1 box; other site
228410002059	GTP/Mg2+ binding site [chemical binding]; other site
228410002060	G2 box; other site
228410002061	Switch I region; other site
228410002062	G3 box; other site
228410002063	Switch II region; other site
228410002064	G4 box; other site
228410002065	Domain of unknown function (DUF3482); Region: DUF3482; pfam11981
228410002066	G5 box; other site
228410002067	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
228410002068	Chain length determinant protein; Region: Wzz; cl15801
228410002069	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
228410002070	active site
228410002071	catalytic residues [active]
228410002072	DNA binding site [nucleotide binding]
228410002073	Int/Topo IB signature motif; other site
228410002074	2 probable transmembrane helices predicted by TMHMM2.0
228410002075	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
228410002076	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
228410002077	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
228410002078	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
228410002079	domain interfaces; other site
228410002080	active site
228410002081	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
228410002082	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
228410002083	active site
228410002084	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
228410002085	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.495 at residue 30
228410002086	1 probable transmembrane helix predicted by TMHMM2.0
228410002087	heme biosynthesis-associated TPR protein; Region: TPR_hemY_coli; TIGR00540
228410002088	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410002089	binding surface
228410002090	TPR motif; other site
228410002091	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.301 at residue 21
228410002092	2 probable transmembrane helices predicted by TMHMM2.0
228410002093	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
228410002094	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
228410002095	catalytic loop [active]
228410002096	iron binding site [ion binding]; other site
228410002097	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
228410002098	FAD binding pocket [chemical binding]; other site
228410002099	FAD binding motif [chemical binding]; other site
228410002100	phosphate binding motif [ion binding]; other site
228410002101	beta-alpha-beta structure motif; other site
228410002102	NAD binding pocket [chemical binding]; other site
228410002103	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
228410002104	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
228410002105	putative NAD(P) binding site [chemical binding]; other site
228410002106	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
228410002107	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
228410002108	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
228410002109	3 probable transmembrane helices predicted by TMHMM2.0
228410002110	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
228410002111	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
228410002112	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
228410002113	5 probable transmembrane helices predicted by TMHMM2.0
228410002114	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
228410002115	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
228410002116	CoA-binding site [chemical binding]; other site
228410002117	hypothetical protein; Provisional; Region: PRK05287
228410002118	lysophospholipid transporter LplT; Provisional; Region: PRK11195
228410002119	12 probable transmembrane helices predicted by TMHMM2.0
228410002120	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
228410002121	10 probable transmembrane helices predicted by TMHMM2.0
228410002122	3 probable transmembrane helices predicted by TMHMM2.0
228410002123	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
228410002124	6 probable transmembrane helices predicted by TMHMM2.0
228410002125	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410002126	S-adenosylmethionine binding site [chemical binding]; other site
228410002127	Protein of unknown function (DUF1347); Region: DUF1347; pfam07079
228410002128	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.880 at residue 21
228410002129	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
228410002130	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
228410002131	active site
228410002132	zinc binding site [ion binding]; other site
228410002133	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.747 at residue 24
228410002134	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
228410002135	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
228410002136	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
228410002137	lipoyl attachment site [posttranslational modification]; other site
228410002138	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
228410002139	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
228410002140	tetramer interface [polypeptide binding]; other site
228410002141	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410002142	catalytic residue [active]
228410002143	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
228410002144	tetramer interface [polypeptide binding]; other site
228410002145	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410002146	catalytic residue [active]
228410002147	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
228410002148	Ribokinase-like subgroup A.  Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_A; cd01942
228410002149	substrate binding site [chemical binding]; other site
228410002150	ATP binding site [chemical binding]; other site
228410002151	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
228410002152	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
228410002153	putative acyl-acceptor binding pocket; other site
228410002154	1 probable transmembrane helix predicted by TMHMM2.0
228410002155	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
228410002156	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
228410002157	active site
228410002158	metal binding site [ion binding]; metal-binding site
228410002159	dihydrodipicolinate reductase; Provisional; Region: PRK00048
228410002160	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
228410002161	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
228410002162	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
228410002163	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
228410002164	ferric uptake regulator; Provisional; Region: fur; PRK09462
228410002165	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
228410002166	metal binding site 2 [ion binding]; metal-binding site
228410002167	putative DNA binding helix; other site
228410002168	metal binding site 1 [ion binding]; metal-binding site
228410002169	dimer interface [polypeptide binding]; other site
228410002170	structural Zn2+ binding site [ion binding]; other site
228410002171	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
228410002172	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
228410002173	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.726 at residue 27
228410002174	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
228410002175	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
228410002176	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
228410002177	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
228410002178	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410002179	motif II; other site
228410002180	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
228410002181	10 probable transmembrane helices predicted by TMHMM2.0
228410002182	Phosphoenolpyruvate:glucose-phosphotransferase regulator; Region: MtfA; pfam06167
228410002183	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH2; cd08183
228410002184	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
228410002185	putative active site [active]
228410002186	metal binding site [ion binding]; metal-binding site
228410002187	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
228410002188	Cupin domain; Region: Cupin_2; pfam07883
228410002189	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
228410002190	trimer interface [polypeptide binding]; other site
228410002191	active site
228410002192	antiporter inner membrane protein; Provisional; Region: PRK11670
228410002193	Domain of unknown function DUF59; Region: DUF59; pfam01883
228410002194	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
228410002195	Walker A motif; other site
228410002196	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
228410002197	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
228410002198	active site
228410002199	HIGH motif; other site
228410002200	KMSKS motif; other site
228410002201	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
228410002202	tRNA binding surface [nucleotide binding]; other site
228410002203	anticodon binding site; other site
228410002204	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
228410002205	dimer interface [polypeptide binding]; other site
228410002206	putative tRNA-binding site [nucleotide binding]; other site
228410002207	aminopeptidase N; Provisional; Region: pepN; PRK14015
228410002208	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
228410002209	Zn binding site [ion binding]; other site
228410002210	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410002211	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410002212	N-terminal plug; other site
228410002213	ligand-binding site [chemical binding]; other site
228410002214	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.751) with cleavage site probability 0.742 at residue 46
228410002215	NE0628, NE0629 and NE0630 are parts of a pseudogene caused by at least 1 premature stop codons and a frameshift
228410002216	pseuso gene; it contains at least 1 frameshift and 1 premature stop; the parts of the original gene are NE0628, NE0629 and NE0630;Cobalamin biosynthesis protein CobN and related Mg-chelatases
228410002217	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.688 at residue 27
228410002218	1 probable transmembrane helix predicted by TMHMM2.0
228410002219	pseuso gene; it contains at least 1 frameshift and 1 premature stop; the parts of the original gene are NE0628, NE0629 and NE0630;CobN/magnesium chelatase
228410002220	pseuso gene; it contains at least 1 frameshift and 1 premature stop; the parts of the original gene are NE0628, NE0629 and NE0630;CobN/magnesium chelatase
228410002221	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
228410002222	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.710) with cleavage site probability 0.546 at residue 34
228410002223	3 probable transmembrane helices predicted by TMHMM2.0
228410002224	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
228410002225	1 probable transmembrane helix predicted by TMHMM2.0
228410002226	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
228410002227	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
228410002228	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
228410002229	homodimer interface [polypeptide binding]; other site
228410002230	Walker A motif; other site
228410002231	ATP binding site [chemical binding]; other site
228410002232	hydroxycobalamin binding site [chemical binding]; other site
228410002233	Walker B motif; other site
228410002234	5 probable transmembrane helices predicted by TMHMM2.0
228410002235	TonB-dependent vitamin B12 receptor; Region: TonB-B12; TIGR01779
228410002236	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410002237	N-terminal plug; other site
228410002238	ligand-binding site [chemical binding]; other site
228410002239	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.978 at residue 25
228410002240	Sec-independent protein translocase protein (TatC); Region: TatC; cl00521
228410002241	6 probable transmembrane helices predicted by TMHMM2.0
228410002242	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
228410002243	1 probable transmembrane helix predicted by TMHMM2.0
228410002244	twin arginine translocase protein A; Provisional; Region: tatA; PRK02958
228410002245	1 probable transmembrane helix predicted by TMHMM2.0
228410002246	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
228410002247	nucleotide binding site/active site [active]
228410002248	HIT family signature motif; other site
228410002249	catalytic residue [active]
228410002250	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
228410002251	metal binding site [ion binding]; metal-binding site
228410002252	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
228410002253	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
228410002254	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
228410002255	substrate binding site [chemical binding]; other site
228410002256	glutamase interaction surface [polypeptide binding]; other site
228410002257	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
228410002258	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
228410002259	catalytic residues [active]
228410002260	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146
228410002261	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
228410002262	putative active site [active]
228410002263	oxyanion strand; other site
228410002264	catalytic triad [active]
228410002265	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
228410002266	putative active site pocket [active]
228410002267	4-fold oligomerization interface [polypeptide binding]; other site
228410002268	metal binding residues [ion binding]; metal-binding site
228410002269	3-fold/trimer interface [polypeptide binding]; other site
228410002270	histidinol-phosphate aminotransferase; Provisional; Region: PRK04870
228410002271	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
228410002272	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410002273	homodimer interface [polypeptide binding]; other site
228410002274	catalytic residue [active]
228410002275	3 probable transmembrane helices predicted by TMHMM2.0
228410002276	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
228410002277	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
228410002278	hydroxyglutarate oxidase; Provisional; Region: PRK11728
228410002279	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
228410002280	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
228410002281	Dehydroquinase class II; Region: DHquinase_II; pfam01220
228410002282	trimer interface [polypeptide binding]; other site
228410002283	active site
228410002284	dimer interface [polypeptide binding]; other site
228410002285	1 probable transmembrane helix predicted by TMHMM2.0
228410002286	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
228410002287	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
228410002288	carboxyltransferase (CT) interaction site; other site
228410002289	biotinylation site [posttranslational modification]; other site
228410002290	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
228410002291	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
228410002292	ATP-grasp domain; Region: ATP-grasp_4; cl17255
228410002293	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
228410002294	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
228410002295	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410002296	S-adenosylmethionine binding site [chemical binding]; other site
228410002297	MJ0042 family finger-like domain; Region: MJ0042_CXXC; TIGR02098
228410002298	Protein of unknown function (DUF3426); Region: DUF3426; pfam11906
228410002299	1 probable transmembrane helix predicted by TMHMM2.0
228410002300	AMIN domain; Region: AMIN; pfam11741
228410002301	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
228410002302	active site
228410002303	metal binding site [ion binding]; metal-binding site
228410002304	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.759 at residue 33
228410002305	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
228410002306	C factor cell-cell signaling protein; Provisional; Region: PRK09009
228410002307	carbonyl reductase sniffer-like, classical (c) SDRs; Region: carb_red_sniffer_like_SDR_c; cd05325
228410002308	NADP binding site [chemical binding]; other site
228410002309	homodimer interface [polypeptide binding]; other site
228410002310	active site
228410002311	S-adenosylmethionine synthetase; Validated; Region: PRK05250
228410002312	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
228410002313	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
228410002314	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
228410002315	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
228410002316	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
228410002317	homotetramer interface [polypeptide binding]; other site
228410002318	ligand binding site [chemical binding]; other site
228410002319	catalytic site [active]
228410002320	NAD binding site [chemical binding]; other site
228410002321	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
228410002322	FAD binding site [chemical binding]; other site
228410002323	ISNE6
228410002324	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
228410002325	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410002326	1 probable transmembrane helix predicted by TMHMM2.0
228410002327	this and 2182 are remnants of the gene destroyed by a transposon;possible exodeoxyribonuclease I
228410002328	this gene and 2181 are remnants of a gene destroyed by a transposon;possible exodeoxyribonuclease I
228410002329	Uncharacterized conserved protein [Function unknown]; Region: COG1432
228410002330	Uncharacterized subfamily of N-terminal LabA-like domains; Region: LabA_like_N_1; cd11297
228410002331	putative metal binding site [ion binding]; other site
228410002332	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
228410002333	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
228410002334	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410002335	dimerization interface [polypeptide binding]; other site
228410002336	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410002337	ATP binding site [chemical binding]; other site
228410002338	Mg2+ binding site [ion binding]; other site
228410002339	G-X-G motif; other site
228410002340	2 probable transmembrane helices predicted by TMHMM2.0
228410002341	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.410 at residue 25
228410002342	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
228410002343	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410002344	active site
228410002345	phosphorylation site [posttranslational modification]
228410002346	intermolecular recognition site; other site
228410002347	dimerization interface [polypeptide binding]; other site
228410002348	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
228410002349	DNA binding site [nucleotide binding]
228410002350	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
228410002351	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.375 at residue 20
228410002352	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
228410002353	Protein export membrane protein; Region: SecD_SecF; cl14618
228410002354	11 probable transmembrane helices predicted by TMHMM2.0
228410002355	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410002356	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.956) with cleavage site probability 0.308 at residue 25
228410002357	exonuclease I; Provisional; Region: sbcB; PRK11779
228410002358	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
228410002359	active site
228410002360	catalytic site [active]
228410002361	substrate binding site [chemical binding]; other site
228410002362	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
228410002363	Protein of unknown function DUF45; Region: DUF45; pfam01863
228410002364	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
228410002365	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
228410002366	Cysteine-rich domain; Region: CCG; pfam02754
228410002367	Cysteine-rich domain; Region: CCG; pfam02754
228410002368	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
228410002369	FAD binding domain; Region: FAD_binding_4; pfam01565
228410002370	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
228410002371	FAD binding domain; Region: FAD_binding_4; pfam01565
228410002372	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
228410002373	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
228410002374	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
228410002375	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
228410002376	substrate binding site; other site
228410002377	tetramer interface; other site
228410002378	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.623) with cleavage site probability 0.384 at residue 23
228410002379	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: rmlC; TIGR01221
228410002380	UDP-glucose 4-epimerase; Region: PLN02240
228410002381	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
228410002382	NAD binding site [chemical binding]; other site
228410002383	homodimer interface [polypeptide binding]; other site
228410002384	active site
228410002385	substrate binding site [chemical binding]; other site
228410002386	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
228410002387	6 probable transmembrane helices predicted by TMHMM2.0
228410002388	4 probable transmembrane helices predicted by TMHMM2.0
228410002389	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.726) with cleavage site probability 0.439 at residue 28
228410002390	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
228410002391	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
228410002392	Cu(I) binding site [ion binding]; other site
228410002393	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.934 at residue 30
228410002394	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cd00919
228410002395	D-pathway; other site
228410002396	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
228410002397	Low-spin heme binding site [chemical binding]; other site
228410002398	Putative water exit pathway; other site
228410002399	Binuclear center (active site) [active]
228410002400	K-pathway; other site
228410002401	Putative proton exit pathway; other site
228410002402	12 probable transmembrane helices predicted by TMHMM2.0
228410002403	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
228410002404	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
228410002405	2 probable transmembrane helices predicted by TMHMM2.0
228410002406	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.755) with cleavage site probability 0.569 at residue 28
228410002407	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
228410002408	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
228410002409	substrate binding site [chemical binding]; other site
228410002410	ligand binding site [chemical binding]; other site
228410002411	Predicted small secreted protein [Function unknown]; Region: COG5510
228410002412	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.940 at residue 20
228410002413	1 probable transmembrane helix predicted by TMHMM2.0
228410002414	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
228410002415	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
228410002416	substrate binding site [chemical binding]; other site
228410002417	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
228410002418	tartrate dehydrogenase; Region: TTC; TIGR02089
228410002419	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
228410002420	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
228410002421	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
228410002422	FimV C-terminal domain; Region: FimV_Cterm; TIGR03504
228410002423	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
228410002424	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
228410002425	dimerization interface 3.5A [polypeptide binding]; other site
228410002426	active site
228410002427	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
228410002428	active site
228410002429	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
228410002430	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
228410002431	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410002432	catalytic residue [active]
228410002433	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
228410002434	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
228410002435	substrate binding site [chemical binding]; other site
228410002436	active site
228410002437	catalytic residues [active]
228410002438	heterodimer interface [polypeptide binding]; other site
228410002439	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
228410002440	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
228410002441	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
228410002442	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
228410002443	Sporulation related domain; Region: SPOR; pfam05036
228410002444	1 probable transmembrane helix predicted by TMHMM2.0
228410002445	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
228410002446	Colicin V production protein; Region: Colicin_V; pfam02674
228410002447	4 probable transmembrane helices predicted by TMHMM2.0
228410002448	amidophosphoribosyltransferase; Provisional; Region: PRK09246
228410002449	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
228410002450	active site
228410002451	tetramer interface [polypeptide binding]; other site
228410002452	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
228410002453	active site
228410002454	O-succinylhomoserine sulfhydrylase; Validated; Region: PRK08133
228410002455	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
228410002456	homodimer interface [polypeptide binding]; other site
228410002457	substrate-cofactor binding pocket; other site
228410002458	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410002459	catalytic residue [active]
228410002460	threonine dehydratase; Reviewed; Region: PRK09224
228410002461	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
228410002462	tetramer interface [polypeptide binding]; other site
228410002463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410002464	catalytic residue [active]
228410002465	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
228410002466	putative Ile/Val binding site [chemical binding]; other site
228410002467	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
228410002468	putative Ile/Val binding site [chemical binding]; other site
228410002469	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
228410002470	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
228410002471	type II secretion system protein D; Region: type_II_gspD; TIGR02517
228410002472	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
228410002473	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
228410002474	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
228410002475	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.950) with cleavage site probability 0.581 at residue 20
228410002476	1 probable transmembrane helix predicted by TMHMM2.0
228410002477	Type II secretion system (T2SS), protein M subtype b; Region: T2SM_b; pfam10741
228410002478	1 probable transmembrane helix predicted by TMHMM2.0
228410002479	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.982) with cleavage site probability 0.773 at residue 21
228410002480	ISNE3
228410002481	putative transposase OrfB; Reviewed; Region: PHA02517
228410002482	HTH-like domain; Region: HTH_21; pfam13276
228410002483	Integrase core domain; Region: rve; pfam00665
228410002484	Integrase core domain; Region: rve_3; pfam13683
228410002485	1 probable transmembrane helix predicted by TMHMM2.0
228410002486	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.805) with cleavage site probability 0.794 at residue 28
228410002487	hypothetical protein; Reviewed; Region: PRK12497
228410002488	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
228410002489	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
228410002490	ISNE2
228410002491	Winged helix-turn helix; Region: HTH_29; pfam13551
228410002492	Integrase core domain; Region: rve; pfam00665
228410002493	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410002494	Integrase core domain; Region: rve_3; pfam13683
228410002495	ISNE5
228410002496	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410002497	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410002498	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410002499	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
228410002500	DNA-binding site [nucleotide binding]; DNA binding site
228410002501	RNA-binding motif; other site
228410002502	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
228410002503	3 probable transmembrane helices predicted by TMHMM2.0
228410002504	hypothetical protein; Reviewed; Region: PRK12497
228410002505	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
228410002506	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410002507	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
228410002508	Walker A/P-loop; other site
228410002509	ATP binding site [chemical binding]; other site
228410002510	Q-loop/lid; other site
228410002511	ABC transporter signature motif; other site
228410002512	Walker B; other site
228410002513	D-loop; other site
228410002514	H-loop/switch region; other site
228410002515	5 probable transmembrane helices predicted by TMHMM2.0
228410002516	Predicted methyltransferases [General function prediction only]; Region: COG0313
228410002517	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
228410002518	putative SAM binding site [chemical binding]; other site
228410002519	putative homodimer interface [polypeptide binding]; other site
228410002520	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
228410002521	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
228410002522	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; cl15373
228410002523	Autotransporter beta-domain; Region: Autotransporter; pfam03797
228410002524	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.971 at residue 23
228410002525	11 probable transmembrane helices predicted by TMHMM2.0
228410002526	1 probable transmembrane helix predicted by TMHMM2.0
228410002527	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.983 at residue 23
228410002528	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
228410002529	active site
228410002530	substrate binding pocket [chemical binding]; other site
228410002531	dimer interface [polypeptide binding]; other site
228410002532	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
228410002533	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
228410002534	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410002535	dimer interface [polypeptide binding]; other site
228410002536	phosphorylation site [posttranslational modification]
228410002537	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410002538	ATP binding site [chemical binding]; other site
228410002539	Mg2+ binding site [ion binding]; other site
228410002540	G-X-G motif; other site
228410002541	2 probable transmembrane helices predicted by TMHMM2.0
228410002542	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.943) with cleavage site probability 0.543 at residue 30
228410002543	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
228410002544	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410002545	active site
228410002546	phosphorylation site [posttranslational modification]
228410002547	intermolecular recognition site; other site
228410002548	dimerization interface [polypeptide binding]; other site
228410002549	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
228410002550	DNA binding site [nucleotide binding]
228410002551	ferric uptake regulator; Provisional; Region: fur; PRK09462
228410002552	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
228410002553	metal binding site 2 [ion binding]; metal-binding site
228410002554	putative DNA binding helix; other site
228410002555	metal binding site 1 [ion binding]; metal-binding site
228410002556	dimer interface [polypeptide binding]; other site
228410002557	structural Zn2+ binding site [ion binding]; other site
228410002558	Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774
228410002559	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410002560	N-terminal plug; other site
228410002561	ligand-binding site [chemical binding]; other site
228410002562	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.931 at residue 34
228410002563	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
228410002564	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
228410002565	active site residue [active]
228410002566	AAA domain; Region: AAA_17; pfam13207
228410002567	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cl00240
228410002568	selenophosphate synthetase; Provisional; Region: PRK00943
228410002569	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
228410002570	dimerization interface [polypeptide binding]; other site
228410002571	putative ATP binding site [chemical binding]; other site
228410002572	ABC transporter ATPase component; Reviewed; Region: PRK11147
228410002573	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410002574	Walker A/P-loop; other site
228410002575	ATP binding site [chemical binding]; other site
228410002576	Q-loop/lid; other site
228410002577	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410002578	ABC transporter; Region: ABC_tran_2; pfam12848
228410002579	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410002580	Cytochrome c553 [Energy production and conversion]; Region: COG2863
228410002581	Cytochrome c553 [Energy production and conversion]; Region: COG2863
228410002582	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 23
228410002583	Domain of unknown function (DUF1841); Region: DUF1841; pfam08897
228410002584	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
228410002585	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
228410002586	putative active site [active]
228410002587	metal binding site [ion binding]; metal-binding site
228410002588	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.946) with cleavage site probability 0.830 at residue 27
228410002589	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
228410002590	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 26
228410002591	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.965) with cleavage site probability 0.957 at residue 30
228410002592	FAD binding domain; Region: FAD_binding_4; pfam01565
228410002593	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
228410002594	Benzyl alcohol dehydrogenase; Region: benzyl_alcohol_DH; cd08278
228410002595	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
228410002596	catalytic Zn binding site [ion binding]; other site
228410002597	NAD binding site [chemical binding]; other site
228410002598	structural Zn binding site [ion binding]; other site
228410002599	5' end of this gene has been destroyed by a transposon, part of the 3' end is also missing; TonB-dependent receptor
228410002600	ISNE7
228410002601	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
228410002602	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; cl01481
228410002603	RES domain; Region: RES; pfam08808
228410002604	ISNE1
228410002605	ISNE3
228410002606	dead gene due to framshift; the rest of the gene is NE0748;possible phage integrase
228410002607	dead gene due to framshift, the rest of the gene is NE0747, and the real start should ovelap with NE0749;Integrase, catalytic core
228410002608	The 5' end of the transposon is interrupted by another transposon;Integrase, catalytic core
228410002609	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.648) with cleavage site probability 0.320 at residue 35
228410002610	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
228410002611	multiple promoter invertase; Provisional; Region: mpi; PRK13413
228410002612	catalytic residues [active]
228410002613	catalytic nucleophile [active]
228410002614	Presynaptic Site I dimer interface [polypeptide binding]; other site
228410002615	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
228410002616	Synaptic Flat tetramer interface [polypeptide binding]; other site
228410002617	Synaptic Site I dimer interface [polypeptide binding]; other site
228410002618	DNA binding site [nucleotide binding]
228410002619	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
228410002620	DNA-binding interface [nucleotide binding]; DNA binding site
228410002621	remnant of a transposon, OrfB is completely missing;IS298, transposase OrfA
228410002622	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
228410002623	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
228410002624	1 probable transmembrane helix predicted by TMHMM2.0
228410002625	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
228410002626	3 probable transmembrane helices predicted by TMHMM2.0
228410002627	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
228410002628	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989
228410002629	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
228410002630	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
228410002631	2 probable transmembrane helices predicted by TMHMM2.0
228410002632	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.928 at residue 39
228410002633	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
228410002634	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410002635	N-terminal plug; other site
228410002636	ligand-binding site [chemical binding]; other site
228410002637	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.913) with cleavage site probability 0.711 at residue 25
228410002638	ribosome maturation protein RimP; Reviewed; Region: PRK00092
228410002639	Sm and related proteins; Region: Sm_like; cl00259
228410002640	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
228410002641	putative oligomer interface [polypeptide binding]; other site
228410002642	putative RNA binding site [nucleotide binding]; other site
228410002643	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
228410002644	NusA N-terminal domain; Region: NusA_N; pfam08529
228410002645	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
228410002646	RNA binding site [nucleotide binding]; other site
228410002647	homodimer interface [polypeptide binding]; other site
228410002648	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
228410002649	G-X-X-G motif; other site
228410002650	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
228410002651	G-X-X-G motif; other site
228410002652	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
228410002653	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
228410002654	translation initiation factor IF-2; Region: IF-2; TIGR00487
228410002655	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
228410002656	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
228410002657	G1 box; other site
228410002658	putative GEF interaction site [polypeptide binding]; other site
228410002659	GTP/Mg2+ binding site [chemical binding]; other site
228410002660	Switch I region; other site
228410002661	G2 box; other site
228410002662	G3 box; other site
228410002663	Switch II region; other site
228410002664	G4 box; other site
228410002665	G5 box; other site
228410002666	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
228410002667	Translation-initiation factor 2; Region: IF-2; pfam11987
228410002668	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
228410002669	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
228410002670	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01851
228410002671	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
228410002672	RNA binding site [nucleotide binding]; other site
228410002673	active site
228410002674	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
228410002675	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
228410002676	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410002677	Walker A/P-loop; other site
228410002678	ATP binding site [chemical binding]; other site
228410002679	Q-loop/lid; other site
228410002680	ABC transporter signature motif; other site
228410002681	Walker B; other site
228410002682	D-loop; other site
228410002683	H-loop/switch region; other site
228410002684	CcmB protein; Region: CcmB; pfam03379
228410002685	6 probable transmembrane helices predicted by TMHMM2.0
228410002686	heme exporter protein CcmC; Region: ccmC; TIGR01191
228410002687	6 probable transmembrane helices predicted by TMHMM2.0
228410002688	CcmE; Region: CcmE; pfam03100
228410002689	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.893 at residue 45
228410002690	1 probable transmembrane helix predicted by TMHMM2.0
228410002691	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
228410002692	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.757) with cleavage site probability 0.373 at residue 20
228410002693	15 probable transmembrane helices predicted by TMHMM2.0
228410002694	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
228410002695	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
228410002696	catalytic residues [active]
228410002697	central insert; other site
228410002698	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.893) with cleavage site probability 0.327 at residue 24
228410002699	1 probable transmembrane helix predicted by TMHMM2.0
228410002700	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
228410002701	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.987 at residue 29
228410002702	2 probable transmembrane helices predicted by TMHMM2.0
228410002703	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
228410002704	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
228410002705	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410002706	binding surface
228410002707	TPR motif; other site
228410002708	2 probable transmembrane helices predicted by TMHMM2.0
228410002709	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
228410002710	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
228410002711	catalytic triad [active]
228410002712	malate dehydrogenase; Provisional; Region: PRK05442
228410002713	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
228410002714	NAD(P) binding site [chemical binding]; other site
228410002715	dimer interface [polypeptide binding]; other site
228410002716	malate binding site [chemical binding]; other site
228410002717	dihydrolipoamide dehydrogenase; Validated; Region: PRK06292
228410002718	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
228410002719	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410002720	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
228410002721	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
228410002722	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
228410002723	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
228410002724	5 probable transmembrane helices predicted by TMHMM2.0
228410002725	PGAP1-like protein; Region: PGAP1; pfam07819
228410002726	1 probable transmembrane helix predicted by TMHMM2.0
228410002727	N-acetylglutamate synthase; Validated; Region: PRK05279
228410002728	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
228410002729	putative feedback inhibition sensing region; other site
228410002730	putative nucleotide binding site [chemical binding]; other site
228410002731	putative substrate binding site [chemical binding]; other site
228410002732	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
228410002733	Coenzyme A binding pocket [chemical binding]; other site
228410002734	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
228410002735	RNA methyltransferase, RsmE family; Region: TIGR00046
228410002736	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
228410002737	putative catalytic residue [active]
228410002738	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
228410002739	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
228410002740	active site
228410002741	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
228410002742	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
228410002743	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
228410002744	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.976) with cleavage site probability 0.597 at residue 29
228410002745	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
228410002746	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.602) with cleavage site probability 0.531 at residue 55
228410002747	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.613 at residue 22
228410002748	excinuclease ABC subunit B; Provisional; Region: PRK05298
228410002749	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410002750	ATP binding site [chemical binding]; other site
228410002751	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410002752	nucleotide binding region [chemical binding]; other site
228410002753	ATP-binding site [chemical binding]; other site
228410002754	Ultra-violet resistance protein B; Region: UvrB; pfam12344
228410002755	UvrB/uvrC motif; Region: UVR; pfam02151
228410002756	aspartate aminotransferase; Provisional; Region: PRK05764
228410002757	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
228410002758	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410002759	homodimer interface [polypeptide binding]; other site
228410002760	catalytic residue [active]
228410002761	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
228410002762	dimerization interface [polypeptide binding]; other site
228410002763	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
228410002764	DNA binding residues [nucleotide binding]
228410002765	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.974) with cleavage site probability 0.857 at residue 28
228410002766	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39G; cd02423
228410002767	putative active site [active]
228410002768	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.968 at residue 20
228410002769	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 at residue 24
228410002770	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
228410002771	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.623 at residue 34
228410002772	Putative phosphatase (DUF442); Region: DUF442; cl17385
228410002773	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.975 at residue 22
228410002774	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
228410002775	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
228410002776	catalytic motif [active]
228410002777	Zn binding site [ion binding]; other site
228410002778	RibD C-terminal domain; Region: RibD_C; cl17279
228410002779	PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family; Region: stp3; TIGR04063
228410002780	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
228410002781	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
228410002782	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
228410002783	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
228410002784	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
228410002785	acyl-activating enzyme (AAE) consensus motif; other site
228410002786	active site
228410002787	AMP binding site [chemical binding]; other site
228410002788	CoA binding site [chemical binding]; other site
228410002789	Exopolysaccharide synthesis, ExoD; Region: ExoD; pfam06055
228410002790	4 probable transmembrane helices predicted by TMHMM2.0
228410002791	1 probable transmembrane helix predicted by TMHMM2.0
228410002792	MobA-like NTP transferase domain; Region: NTP_transf_3; pfam12804
228410002793	active site
228410002794	Predicted permeases [General function prediction only]; Region: COG0795
228410002795	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
228410002796	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.867) with cleavage site probability 0.329 at residue 40
228410002797	6 probable transmembrane helices predicted by TMHMM2.0
228410002798	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
228410002799	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
228410002800	7 probable transmembrane helices predicted by TMHMM2.0
228410002801	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
228410002802	4 probable transmembrane helices predicted by TMHMM2.0
228410002803	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
228410002804	Protein of unknown function (DUF2959); Region: DUF2959; pfam11172
228410002805	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.952) with cleavage site probability 0.589 at residue 26
228410002806	1 probable transmembrane helix predicted by TMHMM2.0
228410002807	Protein of unknown function (DUF721); Region: DUF721; pfam05258
228410002808	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
228410002809	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
228410002810	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
228410002811	SEC-C motif; Region: SEC-C; pfam02810
228410002812	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
228410002813	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
228410002814	[2Fe-2S] cluster binding site [ion binding]; other site
228410002815	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.916) with cleavage site probability 0.531 at residue 34
228410002816	1 probable transmembrane helix predicted by TMHMM2.0
228410002817	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
228410002818	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
228410002819	Qi binding site; other site
228410002820	intrachain domain interface; other site
228410002821	interchain domain interface [polypeptide binding]; other site
228410002822	heme bH binding site [chemical binding]; other site
228410002823	heme bL binding site [chemical binding]; other site
228410002824	Qo binding site; other site
228410002825	interchain domain interface [polypeptide binding]; other site
228410002826	intrachain domain interface; other site
228410002827	Qi binding site; other site
228410002828	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
228410002829	Qo binding site; other site
228410002830	10 probable transmembrane helices predicted by TMHMM2.0
228410002831	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
228410002832	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.940 at residue 21
228410002833	1 probable transmembrane helix predicted by TMHMM2.0
228410002834	stringent starvation protein A; Provisional; Region: sspA; PRK09481
228410002835	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
228410002836	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
228410002837	dimer interface [polypeptide binding]; other site
228410002838	N-terminal domain interface [polypeptide binding]; other site
228410002839	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
228410002840	ISNE1
228410002841	Winged helix-turn helix; Region: HTH_29; pfam13551
228410002842	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410002843	Homeodomain-like domain; Region: HTH_32; pfam13565
228410002844	Integrase core domain; Region: rve; pfam00665
228410002845	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410002846	Integrase core domain; Region: rve_3; pfam13683
228410002847	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410002848	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410002849	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410002850	N-terminal plug; other site
228410002851	ligand-binding site [chemical binding]; other site
228410002852	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410002853	FecR protein; Region: FecR; pfam04773
228410002854	1 probable transmembrane helix predicted by TMHMM2.0
228410002855	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410002856	RNA polymerase sigma factor; Reviewed; Region: PRK12527
228410002857	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410002858	DNA binding residues [nucleotide binding]
228410002859	Formylmethanofuran dehydrogenase subunit E [Energy production and conversion]; Region: COG2191
228410002860	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
228410002861	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
228410002862	putative NAD(P) binding site [chemical binding]; other site
228410002863	putative substrate binding site [chemical binding]; other site
228410002864	catalytic Zn binding site [ion binding]; other site
228410002865	structural Zn binding site [ion binding]; other site
228410002866	dimer interface [polypeptide binding]; other site
228410002867	RES domain; Region: RES; smart00953
228410002868	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
228410002869	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410002870	TPR motif; other site
228410002871	binding surface
228410002872	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.834 at residue 28
228410002873	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.893 at residue 22
228410002874	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410002875	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
228410002876	FtsX-like permease family; Region: FtsX; pfam02687
228410002877	4 probable transmembrane helices predicted by TMHMM2.0
228410002878	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410002879	FtsX-like permease family; Region: FtsX; pfam02687
228410002880	4 probable transmembrane helices predicted by TMHMM2.0
228410002881	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.859 at residue 43
228410002882	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
228410002883	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
228410002884	Walker A/P-loop; other site
228410002885	ATP binding site [chemical binding]; other site
228410002886	Q-loop/lid; other site
228410002887	ABC transporter signature motif; other site
228410002888	Walker B; other site
228410002889	D-loop; other site
228410002890	H-loop/switch region; other site
228410002891	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410002892	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410002893	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410002894	1 probable transmembrane helix predicted by TMHMM2.0
228410002895	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.435 at residue 22
228410002896	Uncharacterized protein conserved in bacteria (DUF2062); Region: DUF2062; pfam09835
228410002897	4 probable transmembrane helices predicted by TMHMM2.0
228410002898	ATP-binding cassette domain of MutS homologs; Region: ABC_MutS_homologs; cd03243
228410002899	Walker A/P-loop; other site
228410002900	ATP binding site [chemical binding]; other site
228410002901	Q-loop/lid; other site
228410002902	ABC transporter signature motif; other site
228410002903	Walker B; other site
228410002904	D-loop; other site
228410002905	H-loop/switch region; other site
228410002906	2 probable transmembrane helices predicted by TMHMM2.0
228410002907	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
228410002908	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
228410002909	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
228410002910	CoenzymeA binding site [chemical binding]; other site
228410002911	subunit interaction site [polypeptide binding]; other site
228410002912	PHB binding site; other site
228410002913	ATP-dependent helicase HrpA; Region: DEAH_box_HrpA; TIGR01967
228410002914	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410002915	ATP binding site [chemical binding]; other site
228410002916	putative Mg++ binding site [ion binding]; other site
228410002917	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410002918	nucleotide binding region [chemical binding]; other site
228410002919	ATP-binding site [chemical binding]; other site
228410002920	Helicase associated domain (HA2); Region: HA2; pfam04408
228410002921	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
228410002922	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
228410002923	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
228410002924	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
228410002925	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
228410002926	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
228410002927	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
228410002928	multiple promoter invertase; Provisional; Region: mpi; PRK13413
228410002929	catalytic residues [active]
228410002930	catalytic nucleophile [active]
228410002931	Presynaptic Site I dimer interface [polypeptide binding]; other site
228410002932	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
228410002933	Synaptic Flat tetramer interface [polypeptide binding]; other site
228410002934	Synaptic Site I dimer interface [polypeptide binding]; other site
228410002935	DNA binding site [nucleotide binding]
228410002936	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
228410002937	DNA-binding interface [nucleotide binding]; DNA binding site
228410002938	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410002939	Domain of unknown function (DUF3330); Region: DUF3330; pfam11809
228410002940	transcriptional regulator MerD; Provisional; Region: PRK13749
228410002941	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
228410002942	DNA binding residues [nucleotide binding]
228410002943	putative mercuric reductase; Provisional; Region: PRK13748
228410002944	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
228410002945	metal-binding site [ion binding]
228410002946	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410002947	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
228410002948	putative mercury transport protein MerC; Provisional; Region: PRK13755
228410002949	4 probable transmembrane helices predicted by TMHMM2.0
228410002950	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.920 at residue 32
228410002951	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
228410002952	metal-binding site [ion binding]
228410002953	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 20
228410002954	putative mercuric transport protein; Provisional; Region: PRK13751
228410002955	3 probable transmembrane helices predicted by TMHMM2.0
228410002956	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.900) with cleavage site probability 0.769 at residue 34
228410002957	putative transcriptional regulator MerR; Provisional; Region: PRK13752
228410002958	Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator; Region: HTH_MerR1; cd04783
228410002959	DNA binding residues [nucleotide binding]
228410002960	dimer interface [polypeptide binding]; other site
228410002961	mercury binding site [ion binding]; other site
228410002962	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
228410002963	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
228410002964	Nuclease-related domain; Region: NERD; pfam08378
228410002965	2 probable transmembrane helices predicted by TMHMM2.0
228410002966	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
228410002967	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
228410002968	putative active site [active]
228410002969	putative metal binding site [ion binding]; other site
228410002970	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
228410002971	catalytic core [active]
228410002972	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
228410002973	5 probable transmembrane helices predicted by TMHMM2.0
228410002974	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
228410002975	putative hydrolase; Provisional; Region: PRK11460
228410002976	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.844 at residue 27
228410002977	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
228410002978	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
228410002979	sulfite reductase subunit beta; Provisional; Region: PRK13504
228410002980	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
228410002981	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
228410002982	sulfite reductase [NADPH] flavoprotein, alpha-component; Region: cysJ; TIGR01931
228410002983	Flavodoxin; Region: Flavodoxin_1; pfam00258
228410002984	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
228410002985	FAD binding pocket [chemical binding]; other site
228410002986	FAD binding motif [chemical binding]; other site
228410002987	catalytic residues [active]
228410002988	NAD binding pocket [chemical binding]; other site
228410002989	phosphate binding motif [ion binding]; other site
228410002990	beta-alpha-beta structure motif; other site
228410002991	transcriptional regulator CysB-like protein; Reviewed; Region: PRK12684
228410002992	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
228410002993	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
228410002994	substrate binding site [chemical binding]; other site
228410002995	dimerization interface [polypeptide binding]; other site
228410002996	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
228410002997	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
228410002998	Active Sites [active]
228410002999	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
228410003000	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
228410003001	Active Sites [active]
228410003002	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
228410003003	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
228410003004	CysD dimerization site [polypeptide binding]; other site
228410003005	G1 box; other site
228410003006	putative GEF interaction site [polypeptide binding]; other site
228410003007	GTP/Mg2+ binding site [chemical binding]; other site
228410003008	Switch I region; other site
228410003009	G2 box; other site
228410003010	G3 box; other site
228410003011	Switch II region; other site
228410003012	G4 box; other site
228410003013	G5 box; other site
228410003014	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
228410003015	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
228410003016	putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Validated; Region: PRK06567
228410003017	FAD/NAD binding domain (electron transfer subunit) of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate...; Region: DHOD_e_trans_like; cd06192
228410003018	FAD binding pocket [chemical binding]; other site
228410003019	FAD binding motif [chemical binding]; other site
228410003020	phosphate binding motif [ion binding]; other site
228410003021	beta-alpha-beta structure motif; other site
228410003022	NAD binding pocket [chemical binding]; other site
228410003023	Iron coordination center [ion binding]; other site
228410003024	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.940) with cleavage site probability 0.929 at residue 21
228410003025	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
228410003026	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
228410003027	ligand binding site [chemical binding]; other site
228410003028	homodimer interface [polypeptide binding]; other site
228410003029	NAD(P) binding site [chemical binding]; other site
228410003030	trimer interface B [polypeptide binding]; other site
228410003031	trimer interface A [polypeptide binding]; other site
228410003032	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
228410003033	3 probable transmembrane helices predicted by TMHMM2.0
228410003034	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
228410003035	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
228410003036	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.972) with cleavage site probability 0.729 at residue 26
228410003037	8 probable transmembrane helices predicted by TMHMM2.0
228410003038	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
228410003039	Sel1-like repeats; Region: SEL1; smart00671
228410003040	Sel1-like repeats; Region: SEL1; smart00671
228410003041	1 probable transmembrane helix predicted by TMHMM2.0
228410003042	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
228410003043	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
228410003044	heme binding site [chemical binding]; other site
228410003045	ferroxidase pore; other site
228410003046	ferroxidase diiron center [ion binding]; other site
228410003047	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4255
228410003048	PAS fold; Region: PAS_4; pfam08448
228410003049	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
228410003050	putative active site [active]
228410003051	heme pocket [chemical binding]; other site
228410003052	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410003053	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.945) with cleavage site probability 0.505 at residue 65
228410003054	2 probable transmembrane helices predicted by TMHMM2.0
228410003055	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
228410003056	ATP binding site [chemical binding]; other site
228410003057	active site
228410003058	substrate binding site [chemical binding]; other site
228410003059	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
228410003060	ATP-grasp domain; Region: ATP-grasp; pfam02222
228410003061	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.943) with cleavage site probability 0.908 at residue 25
228410003062	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
228410003063	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
228410003064	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
228410003065	1 probable transmembrane helix predicted by TMHMM2.0
228410003066	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
228410003067	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
228410003068	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
228410003069	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
228410003070	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
228410003071	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
228410003072	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
228410003073	NAD binding site [chemical binding]; other site
228410003074	dimerization interface [polypeptide binding]; other site
228410003075	product binding site; other site
228410003076	substrate binding site [chemical binding]; other site
228410003077	zinc binding site [ion binding]; other site
228410003078	catalytic residues [active]
228410003079	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
228410003080	hypothetical protein; Provisional; Region: PRK06996
228410003081	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
228410003082	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
228410003083	FMN binding site [chemical binding]; other site
228410003084	active site
228410003085	catalytic residues [active]
228410003086	substrate binding site [chemical binding]; other site
228410003087	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
228410003088	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
228410003089	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
228410003090	purine monophosphate binding site [chemical binding]; other site
228410003091	dimer interface [polypeptide binding]; other site
228410003092	putative catalytic residues [active]
228410003093	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
228410003094	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
228410003095	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
228410003096	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
228410003097	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
228410003098	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
228410003099	Cupin domain; Region: Cupin_2; pfam07883
228410003100	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.319 at residue 21
228410003101	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
228410003102	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
228410003103	ATP binding site [chemical binding]; other site
228410003104	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
228410003105	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
228410003106	OstA-like protein; Region: OstA; cl00844
228410003107	Organic solvent tolerance protein; Region: OstA_C; pfam04453
228410003108	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.995 at residue 24
228410003109	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
228410003110	SurA N-terminal domain; Region: SurA_N; pfam09312
228410003111	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
228410003112	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
228410003113	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.985) with cleavage site probability 0.713 at residue 33
228410003114	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
228410003115	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
228410003116	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
228410003117	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
228410003118	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
228410003119	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
228410003120	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
228410003121	DNA binding site [nucleotide binding]
228410003122	active site
228410003123	phage/plasmid replication protein, gene II/X family; Region: rep_II_X; TIGR01629
228410003124	Phage replication protein CRI; Region: Phage_CRI; pfam05144
228410003125	Phage X family; Region: Phage_X; pfam05155
228410003126	Bacteriophage coat protein B; Region: CoatB; pfam10389
228410003127	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.977 at residue 27
228410003128	2 probable transmembrane helices predicted by TMHMM2.0
228410003129	DNA polymerase III subunit delta'; Validated; Region: PRK07993
228410003130	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.961) with cleavage site probability 0.935 at residue 24
228410003131	2 probable transmembrane helices predicted by TMHMM2.0
228410003132	Protein of unknown function (DUF2523); Region: DUF2523; pfam10734
228410003133	2 probable transmembrane helices predicted by TMHMM2.0
228410003134	Zonular occludens toxin (Zot); Region: Zot; cl17485
228410003135	AAA domain; Region: AAA_22; pfam13401
228410003136	1 probable transmembrane helix predicted by TMHMM2.0
228410003137	1 probable transmembrane helix predicted by TMHMM2.0
228410003138	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
228410003139	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410003140	non-specific DNA binding site [nucleotide binding]; other site
228410003141	salt bridge; other site
228410003142	sequence-specific DNA binding site [nucleotide binding]; other site
228410003143	Phage protein; Region: DUF3653; pfam12375
228410003144	elongation factor P; Validated; Region: PRK00529
228410003145	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
228410003146	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
228410003147	RNA binding site [nucleotide binding]; other site
228410003148	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
228410003149	RNA binding site [nucleotide binding]; other site
228410003150	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4394
228410003151	conserved hypothetical protein, PP_1857 family; Region: efp_adjacent_2; TIGR03837
228410003152	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
228410003153	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
228410003154	putative ligand binding site [chemical binding]; other site
228410003155	putative NAD binding site [chemical binding]; other site
228410003156	catalytic site [active]
228410003157	2 probable transmembrane helices predicted by TMHMM2.0
228410003158	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.835) with cleavage site probability 0.687 at residue 23
228410003159	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
228410003160	Zn binding site [ion binding]; other site
228410003161	M28 Zn-Peptidases containing a PA domain insert and associated with a PDZ domain; Region: M28_like_PA_PDZ_associated; cd05663
228410003162	Peptidase family M28; Region: Peptidase_M28; pfam04389
228410003163	metal binding site [ion binding]; metal-binding site
228410003164	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
228410003165	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.990 at residue 27
228410003166	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410003167	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410003168	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410003169	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.986 at residue 35
228410003170	Cytochrome c; Region: Cytochrom_C; pfam00034
228410003171	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
228410003172	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
228410003173	Cytochrome c; Region: Cytochrom_C; pfam00034
228410003174	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.944 at residue 31
228410003175	Cytochrome c; Region: Cytochrom_C; cl11414
228410003176	Cytochrome c; Region: Cytochrom_C; cl11414
228410003177	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 19
228410003178	Protein of unknown function (DUF3293); Region: DUF3293; pfam11697
228410003179	FtsH Extracellular; Region: FtsH_ext; pfam06480
228410003180	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
228410003181	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410003182	Walker A motif; other site
228410003183	ATP binding site [chemical binding]; other site
228410003184	Walker B motif; other site
228410003185	arginine finger; other site
228410003186	Peptidase family M41; Region: Peptidase_M41; pfam01434
228410003187	2 probable transmembrane helices predicted by TMHMM2.0
228410003188	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
228410003189	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
228410003190	substrate binding site [chemical binding]; other site
228410003191	catalytic Zn binding site [ion binding]; other site
228410003192	NAD binding site [chemical binding]; other site
228410003193	structural Zn binding site [ion binding]; other site
228410003194	dimer interface [polypeptide binding]; other site
228410003195	S-formylglutathione hydrolase; Region: PLN02442
228410003196	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
228410003197	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
228410003198	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase; Region: PLPDE_III_ODC; cd00622
228410003199	active site
228410003200	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
228410003201	dimer interface [polypeptide binding]; other site
228410003202	catalytic residues [active]
228410003203	substrate binding site [chemical binding]; other site
228410003204	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
228410003205	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 25
228410003206	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
228410003207	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
228410003208	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410003209	FeS/SAM binding site; other site
228410003210	PEP-CTERM protein-sorting domain; Region: PEP_exosort; TIGR02595
228410003211	1 probable transmembrane helix predicted by TMHMM2.0
228410003212	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 36
228410003213	BolA-like protein; Region: BolA; cl00386
228410003214	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
228410003215	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.981) with cleavage site probability 0.206 at residue 29
228410003216	1 probable transmembrane helix predicted by TMHMM2.0
228410003217	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 at residue 23
228410003218	3 probable transmembrane helices predicted by TMHMM2.0
228410003219	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
228410003220	Repair protein; Region: Repair_PSII; pfam04536
228410003221	Repair protein; Region: Repair_PSII; pfam04536
228410003222	RNA polymerase factor sigma-70; Validated; Region: PRK09047
228410003223	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003224	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410003225	DNA binding residues [nucleotide binding]
228410003226	Protein of unknown function (DUF3619); Region: DUF3619; pfam12279
228410003227	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
228410003228	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410003229	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410003230	Walker A/P-loop; other site
228410003231	ATP binding site [chemical binding]; other site
228410003232	Q-loop/lid; other site
228410003233	ABC transporter signature motif; other site
228410003234	Walker B; other site
228410003235	D-loop; other site
228410003236	H-loop/switch region; other site
228410003237	6 probable transmembrane helices predicted by TMHMM2.0
228410003238	Domain of unknown function (DUF1854); Region: DUF1854; pfam08909
228410003239	PemK-like protein; Region: PemK; pfam02452
228410003240	cyanophycin synthetase; Provisional; Region: PRK14016
228410003241	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
228410003242	cyanophycin synthetase; Provisional; Region: PRK14016
228410003243	ATP-grasp domain; Region: ATP-grasp_4; cl17255
228410003244	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
228410003245	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
228410003246	nitrite reductase, copper-containing; Region: Cu_nitrite_red; TIGR02376
228410003247	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
228410003248	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.946 at residue 25
228410003249	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
228410003250	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
228410003251	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.832 at residue 30
228410003252	1 probable transmembrane helix predicted by TMHMM2.0
228410003253	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
228410003254	Cytochrome c; Region: Cytochrom_C; pfam00034
228410003255	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 23
228410003256	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
228410003257	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
228410003258	Multicopper oxidase; Region: Cu-oxidase; pfam00394
228410003259	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.954 at residue 44
228410003260	1 probable transmembrane helix predicted by TMHMM2.0
228410003261	Predicted transcriptional regulator [Transcription]; Region: COG1959
228410003262	Transcriptional regulator; Region: Rrf2; cl17282
228410003263	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
228410003264	Family of unknown function (DUF490); Region: DUF490; pfam04357
228410003265	1 probable transmembrane helix predicted by TMHMM2.0
228410003266	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
228410003267	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
228410003268	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
228410003269	Surface antigen; Region: Bac_surface_Ag; pfam01103
228410003270	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.553 at residue 19
228410003271	Family-5 Uracil-DNA glycosylases (UDG), found in thermophilic organisms; Region: UDG_F5_TTUDGB_like; cd10031
228410003272	Fe-S cluster binding site [ion binding]; other site
228410003273	DNA binding site [nucleotide binding]
228410003274	active site
228410003275	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
228410003276	active site 1 [active]
228410003277	dimer interface [polypeptide binding]; other site
228410003278	hexamer interface [polypeptide binding]; other site
228410003279	active site 2 [active]
228410003280	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
228410003281	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
228410003282	GIY-YIG motif/motif A; other site
228410003283	active site
228410003284	catalytic site [active]
228410003285	putative DNA binding site [nucleotide binding]; other site
228410003286	metal binding site [ion binding]; metal-binding site
228410003287	UvrB/uvrC motif; Region: UVR; pfam02151
228410003288	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
228410003289	ISNE2
228410003290	Winged helix-turn helix; Region: HTH_29; pfam13551
228410003291	Integrase core domain; Region: rve; pfam00665
228410003292	3' half of this gene has been destroyed by a transposon; outer membrane receptor protein
228410003293	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 36
228410003294	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
228410003295	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410003296	active site
228410003297	phosphorylation site [posttranslational modification]
228410003298	intermolecular recognition site; other site
228410003299	dimerization interface [polypeptide binding]; other site
228410003300	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
228410003301	DNA binding site [nucleotide binding]
228410003302	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.951) with cleavage site probability 0.655 at residue 31
228410003303	2 probable transmembrane helices predicted by TMHMM2.0
228410003304	ISNE1
228410003305	Winged helix-turn helix; Region: HTH_29; pfam13551
228410003306	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410003307	Homeodomain-like domain; Region: HTH_32; pfam13565
228410003308	Integrase core domain; Region: rve; pfam00665
228410003309	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410003310	Integrase core domain; Region: rve_3; pfam13683
228410003311	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
228410003312	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
228410003313	1 probable transmembrane helix predicted by TMHMM2.0
228410003314	1 probable transmembrane helix predicted by TMHMM2.0
228410003315	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.938 at residue 23
228410003316	2 probable transmembrane helices predicted by TMHMM2.0
228410003317	methane monooxygenase/ammonia monooxygenase, subunit B; Region: CH4_NH3mon_ox_B; TIGR03079
228410003318	Monooxygenase subunit B protein; Region: Monooxygenase_B; pfam04744
228410003319	3 probable transmembrane helices predicted by TMHMM2.0
228410003320	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.953 at residue 26
228410003321	methane monooxygenase/ammonia monooxygenase, subunit A; Region: CH4_NH3mon_ox_A; TIGR03080
228410003322	6 probable transmembrane helices predicted by TMHMM2.0
228410003323	Ammonia monooxygenase/methane monooxygenase, subunit C; Region: AmoC; pfam04896
228410003324	6 probable transmembrane helices predicted by TMHMM2.0
228410003325	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
228410003326	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
228410003327	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
228410003328	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410003329	motif II; other site
228410003330	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
228410003331	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
228410003332	Peptidase family M23; Region: Peptidase_M23; pfam01551
228410003333	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.773 at residue 21
228410003334	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
228410003335	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410003336	S-adenosylmethionine binding site [chemical binding]; other site
228410003337	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
228410003338	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
228410003339	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
228410003340	DNA binding residues [nucleotide binding]
228410003341	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
228410003342	IHF - DNA interface [nucleotide binding]; other site
228410003343	IHF dimer interface [polypeptide binding]; other site
228410003344	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
228410003345	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
228410003346	putative tRNA-binding site [nucleotide binding]; other site
228410003347	B3/4 domain; Region: B3_4; pfam03483
228410003348	tRNA synthetase B5 domain; Region: B5; smart00874
228410003349	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
228410003350	dimer interface [polypeptide binding]; other site
228410003351	motif 1; other site
228410003352	motif 3; other site
228410003353	motif 2; other site
228410003354	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
228410003355	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
228410003356	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
228410003357	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
228410003358	dimer interface [polypeptide binding]; other site
228410003359	motif 1; other site
228410003360	active site
228410003361	motif 2; other site
228410003362	motif 3; other site
228410003363	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
228410003364	23S rRNA binding site [nucleotide binding]; other site
228410003365	L21 binding site [polypeptide binding]; other site
228410003366	L13 binding site [polypeptide binding]; other site
228410003367	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
228410003368	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.959) with cleavage site probability 0.952 at residue 53
228410003369	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
228410003370	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
228410003371	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
228410003372	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
228410003373	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
228410003374	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
228410003375	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
228410003376	active site
228410003377	dimer interface [polypeptide binding]; other site
228410003378	motif 1; other site
228410003379	motif 2; other site
228410003380	motif 3; other site
228410003381	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
228410003382	anticodon binding site; other site
228410003383	NapC/NirT cytochrome c family, N-terminal region; Region: Cytochrom_NNT; pfam03264
228410003384	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
228410003385	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.690 at residue 29
228410003386	1 probable transmembrane helix predicted by TMHMM2.0
228410003387	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
228410003388	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 25
228410003389	1 probable transmembrane helix predicted by TMHMM2.0
228410003390	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
228410003391	Seven times multi-haem cytochrome CxxCH; Region: Multi-haem_cyto; pfam13447
228410003392	1 probable transmembrane helix predicted by TMHMM2.0
228410003393	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 25
228410003394	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
228410003395	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
228410003396	Tfp pilus assembly protein, ATPase PilU [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilU; COG5008
228410003397	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
228410003398	Walker A motif; other site
228410003399	ATP binding site [chemical binding]; other site
228410003400	Walker B motif; other site
228410003401	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
228410003402	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
228410003403	Walker A motif; other site
228410003404	ATP binding site [chemical binding]; other site
228410003405	Walker B motif; other site
228410003406	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
228410003407	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
228410003408	catalytic residue [active]
228410003409	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
228410003410	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
228410003411	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
228410003412	active site
228410003413	(T/H)XGH motif; other site
228410003414	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
228410003415	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410003416	S-adenosylmethionine binding site [chemical binding]; other site
228410003417	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
228410003418	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
228410003419	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
228410003420	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
228410003421	dimer interface [polypeptide binding]; other site
228410003422	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
228410003423	Peptidase family M54, also called archaemetzincins or archaelysins; Region: Peptidase_M54; cl17349
228410003424	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.836 at residue 22
228410003425	PemK-like protein; Region: PemK; cl00995
228410003426	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
228410003427	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
228410003428	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
228410003429	Walker A/P-loop; other site
228410003430	ATP binding site [chemical binding]; other site
228410003431	Q-loop/lid; other site
228410003432	ABC transporter signature motif; other site
228410003433	Walker B; other site
228410003434	D-loop; other site
228410003435	H-loop/switch region; other site
228410003436	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
228410003437	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
228410003438	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410003439	dimer interface [polypeptide binding]; other site
228410003440	conserved gate region; other site
228410003441	putative PBP binding loops; other site
228410003442	ABC-ATPase subunit interface; other site
228410003443	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
228410003444	12 probable transmembrane helices predicted by TMHMM2.0
228410003445	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.912) with cleavage site probability 0.814 at residue 36
228410003446	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410003447	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410003448	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410003449	N-terminal plug; other site
228410003450	ligand-binding site [chemical binding]; other site
228410003451	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.977 at residue 42
228410003452	1 probable transmembrane helix predicted by TMHMM2.0
228410003453	fec operon regulator FecR; Reviewed; Region: PRK09774
228410003454	FecR protein; Region: FecR; pfam04773
228410003455	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410003456	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003457	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
228410003458	DNA binding residues [nucleotide binding]
228410003459	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
228410003460	endonuclease III; Region: ENDO3c; smart00478
228410003461	minor groove reading motif; other site
228410003462	helix-hairpin-helix signature motif; other site
228410003463	substrate binding pocket [chemical binding]; other site
228410003464	active site
228410003465	cell division protein MraZ; Reviewed; Region: PRK00326
228410003466	MraZ protein; Region: MraZ; pfam02381
228410003467	MraZ protein; Region: MraZ; pfam02381
228410003468	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
228410003469	MraW methylase family; Region: Methyltransf_5; cl17771
228410003470	Cell division protein FtsL; Region: FtsL; pfam04999
228410003471	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.882) with cleavage site probability 0.764 at residue 23
228410003472	1 probable transmembrane helix predicted by TMHMM2.0
228410003473	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
228410003474	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
228410003475	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
228410003476	1 probable transmembrane helix predicted by TMHMM2.0
228410003477	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
228410003478	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
228410003479	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
228410003480	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
228410003481	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
228410003482	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
228410003483	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
228410003484	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
228410003485	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
228410003486	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
228410003487	Mg++ binding site [ion binding]; other site
228410003488	putative catalytic motif [active]
228410003489	putative substrate binding site [chemical binding]; other site
228410003490	10 probable transmembrane helices predicted by TMHMM2.0
228410003491	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02006
228410003492	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
228410003493	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
228410003494	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
228410003495	cell division protein FtsW; Region: ftsW; TIGR02614
228410003496	10 probable transmembrane helices predicted by TMHMM2.0
228410003497	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
228410003498	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
228410003499	active site
228410003500	homodimer interface [polypeptide binding]; other site
228410003501	1 probable transmembrane helix predicted by TMHMM2.0
228410003502	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
228410003503	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
228410003504	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
228410003505	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
228410003506	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
228410003507	FAD binding domain; Region: FAD_binding_4; pfam01565
228410003508	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
228410003509	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
228410003510	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
228410003511	ATP-grasp domain; Region: ATP-grasp_4; cl17255
228410003512	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
228410003513	Cell division protein FtsQ; Region: FtsQ; pfam03799
228410003514	1 probable transmembrane helix predicted by TMHMM2.0
228410003515	cell division protein FtsA; Region: ftsA; TIGR01174
228410003516	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
228410003517	nucleotide binding site [chemical binding]; other site
228410003518	Cell division protein FtsA; Region: FtsA; pfam14450
228410003519	cell division protein FtsZ; Validated; Region: PRK09330
228410003520	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
228410003521	nucleotide binding site [chemical binding]; other site
228410003522	SulA interaction site; other site
228410003523	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
228410003524	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410003525	dimer interface [polypeptide binding]; other site
228410003526	conserved gate region; other site
228410003527	putative PBP binding loops; other site
228410003528	ABC-ATPase subunit interface; other site
228410003529	6 probable transmembrane helices predicted by TMHMM2.0
228410003530	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
228410003531	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410003532	ABC-ATPase subunit interface; other site
228410003533	6 probable transmembrane helices predicted by TMHMM2.0
228410003534	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14252
228410003535	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
228410003536	Walker A/P-loop; other site
228410003537	ATP binding site [chemical binding]; other site
228410003538	Q-loop/lid; other site
228410003539	ABC transporter signature motif; other site
228410003540	Walker B; other site
228410003541	D-loop; other site
228410003542	H-loop/switch region; other site
228410003543	aconitate hydratase; Validated; Region: PRK09277
228410003544	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
228410003545	substrate binding site [chemical binding]; other site
228410003546	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
228410003547	ligand binding site [chemical binding]; other site
228410003548	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
228410003549	substrate binding site [chemical binding]; other site
228410003550	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.950) with cleavage site probability 0.919 at residue 30
228410003551	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
228410003552	active site
228410003553	phosphate binding residues; other site
228410003554	catalytic residues [active]
228410003555	Predicted flavoprotein [General function prediction only]; Region: COG0431
228410003556	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
228410003557	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
228410003558	feedback inhibition sensing region; other site
228410003559	homohexameric interface [polypeptide binding]; other site
228410003560	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
228410003561	nucleotide binding site [chemical binding]; other site
228410003562	N-acetyl-L-glutamate binding site [chemical binding]; other site
228410003563	CheW-like domain; Region: CheW; pfam01584
228410003564	Response regulator receiver domain; Region: Response_reg; pfam00072
228410003565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410003566	active site
228410003567	phosphorylation site [posttranslational modification]
228410003568	intermolecular recognition site; other site
228410003569	dimerization interface [polypeptide binding]; other site
228410003570	outer membrane lipoprotein; Provisional; Region: PRK11023
228410003571	BON domain; Region: BON; pfam04972
228410003572	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.914) with cleavage site probability 0.465 at residue 34
228410003573	1 probable transmembrane helix predicted by TMHMM2.0
228410003574	FAD binding domain; Region: FAD_binding_4; pfam01565
228410003575	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
228410003576	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
228410003577	UbiA prenyltransferase family; Region: UbiA; pfam01040
228410003578	9 probable transmembrane helices predicted by TMHMM2.0
228410003579	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
228410003580	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.931) with cleavage site probability 0.697 at residue 33
228410003581	1 probable transmembrane helix predicted by TMHMM2.0
228410003582	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
228410003583	2 probable transmembrane helices predicted by TMHMM2.0
228410003584	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.699) with cleavage site probability 0.585 at residue 37
228410003585	Cytochrome c oxidase subunit III.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665
228410003586	Subunit III/VIIa interface [polypeptide binding]; other site
228410003587	Phospholipid binding site [chemical binding]; other site
228410003588	Subunit I/III interface [polypeptide binding]; other site
228410003589	Subunit III/VIb interface [polypeptide binding]; other site
228410003590	Subunit III/VIa interface; other site
228410003591	Subunit III/Vb interface [polypeptide binding]; other site
228410003592	7 probable transmembrane helices predicted by TMHMM2.0
228410003593	Protein of unknown function (DUF2970); Region: DUF2970; pfam11174
228410003594	1 probable transmembrane helix predicted by TMHMM2.0
228410003595	cytochrome C oxidase assembly protein; Provisional; Region: PRK05089
228410003596	1 probable transmembrane helix predicted by TMHMM2.0
228410003597	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
228410003598	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
228410003599	Subunit I/III interface [polypeptide binding]; other site
228410003600	D-pathway; other site
228410003601	Subunit I/VIIc interface [polypeptide binding]; other site
228410003602	Subunit I/IV interface [polypeptide binding]; other site
228410003603	Subunit I/II interface [polypeptide binding]; other site
228410003604	Low-spin heme (heme a) binding site [chemical binding]; other site
228410003605	Subunit I/VIIa interface [polypeptide binding]; other site
228410003606	Subunit I/VIa interface [polypeptide binding]; other site
228410003607	Dimer interface; other site
228410003608	Putative water exit pathway; other site
228410003609	Binuclear center (heme a3/CuB) [ion binding]; other site
228410003610	K-pathway; other site
228410003611	Subunit I/Vb interface [polypeptide binding]; other site
228410003612	Putative proton exit pathway; other site
228410003613	Subunit I/VIb interface; other site
228410003614	Subunit I/VIc interface [polypeptide binding]; other site
228410003615	Electron transfer pathway; other site
228410003616	Subunit I/VIIIb interface [polypeptide binding]; other site
228410003617	Subunit I/VIIb interface [polypeptide binding]; other site
228410003618	12 probable transmembrane helices predicted by TMHMM2.0
228410003619	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
228410003620	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
228410003621	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
228410003622	3 probable transmembrane helices predicted by TMHMM2.0
228410003623	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.965 at residue 26
228410003624	YccA-like proteins; Region: YccA_like; cd10433
228410003625	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
228410003626	7 probable transmembrane helices predicted by TMHMM2.0
228410003627	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
228410003628	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
228410003629	metal-binding site [ion binding]
228410003630	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
228410003631	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
228410003632	metal-binding site [ion binding]
228410003633	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
228410003634	Soluble P-type ATPase [General function prediction only]; Region: COG4087
228410003635	8 probable transmembrane helices predicted by TMHMM2.0
228410003636	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
228410003637	metal-binding site [ion binding]
228410003638	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
228410003639	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
228410003640	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
228410003641	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
228410003642	Ligand Binding Site [chemical binding]; other site
228410003643	TilS substrate binding domain; Region: TilS; pfam09179
228410003644	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
228410003645	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
228410003646	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
228410003647	NADP binding site [chemical binding]; other site
228410003648	active site
228410003649	putative substrate binding site [chemical binding]; other site
228410003650	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
228410003651	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
228410003652	tandem repeat interface [polypeptide binding]; other site
228410003653	oligomer interface [polypeptide binding]; other site
228410003654	active site residues [active]
228410003655	1 probable transmembrane helix predicted by TMHMM2.0
228410003656	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
228410003657	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
228410003658	ligand binding site [chemical binding]; other site
228410003659	2 probable transmembrane helices predicted by TMHMM2.0
228410003660	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.943) with cleavage site probability 0.261 at residue 24
228410003661	Bacterial SH3 domain; Region: SH3_4; pfam06347
228410003662	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
228410003663	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
228410003664	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.871) with cleavage site probability 0.264 at residue 29
228410003665	1 probable transmembrane helix predicted by TMHMM2.0
228410003666	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
228410003667	Ligand Binding Site [chemical binding]; other site
228410003668	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
228410003669	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
228410003670	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.951 at residue 34
228410003671	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
228410003672	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410003673	dimer interface [polypeptide binding]; other site
228410003674	conserved gate region; other site
228410003675	putative PBP binding loops; other site
228410003676	ABC-ATPase subunit interface; other site
228410003677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410003678	dimer interface [polypeptide binding]; other site
228410003679	conserved gate region; other site
228410003680	putative PBP binding loops; other site
228410003681	ABC-ATPase subunit interface; other site
228410003682	11 probable transmembrane helices predicted by TMHMM2.0
228410003683	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
228410003684	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
228410003685	Walker A/P-loop; other site
228410003686	ATP binding site [chemical binding]; other site
228410003687	Q-loop/lid; other site
228410003688	ABC transporter signature motif; other site
228410003689	Walker B; other site
228410003690	D-loop; other site
228410003691	H-loop/switch region; other site
228410003692	TOBE domain; Region: TOBE_2; pfam08402
228410003693	hypothetical protein; Provisional; Region: PRK02877
228410003694	Transglycosylase SLT domain; Region: SLT_2; pfam13406
228410003695	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
228410003696	N-acetyl-D-glucosamine binding site [chemical binding]; other site
228410003697	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.961) with cleavage site probability 0.889 at residue 41
228410003698	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
228410003699	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
228410003700	catalytic residues [active]
228410003701	transcription termination factor Rho; Provisional; Region: rho; PRK09376
228410003702	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
228410003703	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
228410003704	RNA binding site [nucleotide binding]; other site
228410003705	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
228410003706	multimer interface [polypeptide binding]; other site
228410003707	Walker A motif; other site
228410003708	ATP binding site [chemical binding]; other site
228410003709	Walker B motif; other site
228410003710	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
228410003711	NE1037 and NE1038 are 2 parts of a pseudogene caused by a frameshift
228410003712	NE1037 and NE1038 are 2 parts of a dead gene due to a frameshift;TonB-dependent receptor protein
228410003713	NE1037 and NE1038 are 2 parts of a dead gene due to a frameshift;possible tonB-dependent receptor protein
228410003714	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.733 at residue 27
228410003715	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.710 at residue 33
228410003716	1 probable transmembrane helix predicted by TMHMM2.0
228410003718	NE1039 and NE1040 are 2 parts of a dead gene due to a frameshift;possible transmembrane sensor
228410003719	NE1039 and NE1040 are 2 parts of a dead gene due to a frameshift; transmembrane sensor
228410003720	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
228410003721	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410003722	DNA binding residues [nucleotide binding]
228410003723	1 probable transmembrane helix predicted by TMHMM2.0
228410003724	Septum formation initiator; Region: DivIC; cl17659
228410003725	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
228410003726	1 probable transmembrane helix predicted by TMHMM2.0
228410003727	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.637) with cleavage site probability 0.589 at residue 16
228410003728	enolase; Provisional; Region: eno; PRK00077
228410003729	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
228410003730	dimer interface [polypeptide binding]; other site
228410003731	metal binding site [ion binding]; metal-binding site
228410003732	substrate binding pocket [chemical binding]; other site
228410003733	CTP synthetase; Validated; Region: pyrG; PRK05380
228410003734	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
228410003735	Catalytic site [active]
228410003736	active site
228410003737	UTP binding site [chemical binding]; other site
228410003738	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
228410003739	active site
228410003740	putative oxyanion hole; other site
228410003741	catalytic triad [active]
228410003742	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.972) with cleavage site probability 0.898 at residue 26
228410003743	3 probable transmembrane helices predicted by TMHMM2.0
228410003744	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
228410003745	Iron-sulfur protein interface; other site
228410003746	proximal quinone binding site [chemical binding]; other site
228410003747	SdhD (CybS) interface [polypeptide binding]; other site
228410003748	proximal heme binding site [chemical binding]; other site
228410003749	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
228410003750	SdhC subunit interface [polypeptide binding]; other site
228410003751	proximal heme binding site [chemical binding]; other site
228410003752	cardiolipin binding site; other site
228410003753	Iron-sulfur protein interface; other site
228410003754	proximal quinone binding site [chemical binding]; other site
228410003755	3 probable transmembrane helices predicted by TMHMM2.0
228410003756	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07057
228410003757	L-aspartate oxidase; Provisional; Region: PRK06175
228410003758	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
228410003759	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.678) with cleavage site probability 0.306 at residue 26
228410003760	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
228410003761	Ankyrin repeat; Region: Ank; pfam00023
228410003762	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
228410003763	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
228410003764	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
228410003765	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
228410003766	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 36
228410003767	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
228410003768	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
228410003769	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
228410003770	5 probable transmembrane helices predicted by TMHMM2.0
228410003771	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
228410003772	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
228410003773	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.697 at residue 22
228410003774	recombination factor protein RarA; Reviewed; Region: PRK13342
228410003775	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410003776	Walker A motif; other site
228410003777	ATP binding site [chemical binding]; other site
228410003778	Walker B motif; other site
228410003779	arginine finger; other site
228410003780	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
228410003781	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
228410003782	12 probable transmembrane helices predicted by TMHMM2.0
228410003783	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.881 at residue 32
228410003784	1 probable transmembrane helix predicted by TMHMM2.0
228410003785	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
228410003786	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
228410003787	Walker A/P-loop; other site
228410003788	ATP binding site [chemical binding]; other site
228410003789	Q-loop/lid; other site
228410003790	ABC transporter signature motif; other site
228410003791	Walker B; other site
228410003792	D-loop; other site
228410003793	H-loop/switch region; other site
228410003794	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
228410003795	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410003796	FtsX-like permease family; Region: FtsX; pfam02687
228410003797	4 probable transmembrane helices predicted by TMHMM2.0
228410003798	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.794) with cleavage site probability 0.244 at residue 39
228410003799	PEP-CTERM motif; Region: VPEP; pfam07589
228410003800	1 probable transmembrane helix predicted by TMHMM2.0
228410003801	Urea transporter; Region: UT; cl01829
228410003802	9 probable transmembrane helices predicted by TMHMM2.0
228410003803	3' remnant of gene interrupted by an IS element; outer membrane receptor protein
228410003804	Winged helix-turn helix; Region: HTH_29; pfam13551
228410003805	Integrase core domain; Region: rve; pfam00665
228410003806	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410003807	Integrase core domain; Region: rve_3; pfam13683
228410003808	ISNE2
228410003809	NE1062 and NE1063 are 2 parts of a pseudogene caused by a frameshift
228410003810	NE1062 and NE1063 are 2 parts of a dead gene due to a frameshift;TonB-dependent receptor protein
228410003811	NE1062 and NE1063 are 2 parts of a dead gene due to a frameshift;possible tonB-dependent receptor protein
228410003812	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.989 at residue 62
228410003813	1 probable transmembrane helix predicted by TMHMM2.0
228410003814	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410003815	oligomeric interface; other site
228410003816	putative active site [active]
228410003817	homodimer interface [polypeptide binding]; other site
228410003818	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
228410003819	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
228410003820	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410003821	homodimer interface [polypeptide binding]; other site
228410003822	putative active site [active]
228410003823	NE1068 and NE1069 are 2 parts of a pseudogene caused by 2 premature stop codons
228410003824	pseudogene, contains 2 premature stop codons, the other part of the gene is NE1069; transmembrane sensor
228410003825	pseudogene, contains 2 premature stop codons, the other part of the gene is NE1068;Helix-turn-helix motif
228410003826	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410003827	FecR protein; Region: FecR; pfam04773
228410003828	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410003829	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003830	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410003831	DNA binding residues [nucleotide binding]
228410003832	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410003833	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410003834	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410003835	N-terminal plug; other site
228410003836	ligand-binding site [chemical binding]; other site
228410003837	dead gene, only the 3' end of the gene;Site-specific recombinase
228410003838	Uncharacterized conserved protein [Function unknown]; Region: COG2361
228410003839	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
228410003840	active site
228410003841	NTP binding site [chemical binding]; other site
228410003842	metal binding triad [ion binding]; metal-binding site
228410003843	antibiotic binding site [chemical binding]; other site
228410003844	CcdB protein; Region: CcdB; cl03380
228410003845	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
228410003846	fec operon regulator FecR; Reviewed; Region: PRK09774
228410003847	FecR protein; Region: FecR; pfam04773
228410003848	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410003849	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003850	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410003851	DNA binding residues [nucleotide binding]
228410003852	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
228410003853	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.566 at residue 21
228410003854	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
228410003855	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
228410003856	Walker A/P-loop; other site
228410003857	ATP binding site [chemical binding]; other site
228410003858	Q-loop/lid; other site
228410003859	ABC transporter signature motif; other site
228410003860	Walker B; other site
228410003861	D-loop; other site
228410003862	H-loop/switch region; other site
228410003863	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410003864	FtsX-like permease family; Region: FtsX; pfam02687
228410003865	4 probable transmembrane helices predicted by TMHMM2.0
228410003866	macrolide transporter subunit MacA; Provisional; Region: PRK11578
228410003867	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410003868	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410003869	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.866) with cleavage site probability 0.639 at residue 35
228410003870	1 probable transmembrane helix predicted by TMHMM2.0
228410003871	Protein of unknown function (DUF3325); Region: DUF3325; pfam11804
228410003872	4 probable transmembrane helices predicted by TMHMM2.0
228410003873	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.724 at residue 25
228410003874	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
228410003875	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
228410003876	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
228410003877	11 probable transmembrane helices predicted by TMHMM2.0
228410003878	fec operon regulator FecR; Reviewed; Region: PRK09774
228410003879	FecR protein; Region: FecR; pfam04773
228410003880	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410003881	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003882	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410003883	DNA binding residues [nucleotide binding]
228410003884	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
228410003885	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410003886	N-terminal plug; other site
228410003887	ligand-binding site [chemical binding]; other site
228410003888	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.978 at residue 45
228410003889	1 probable transmembrane helix predicted by TMHMM2.0
228410003890	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410003891	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
228410003892	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410003893	N-terminal plug; other site
228410003894	ligand-binding site [chemical binding]; other site
228410003895	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 39
228410003896	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410003897	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410003898	N-terminal plug; other site
228410003899	ligand-binding site [chemical binding]; other site
228410003900	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.974 at residue 21
228410003901	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
228410003902	NE1092 and NE1094 are two parts of a pseudogene caused by the interruption of an IS element
228410003903	NE1092 and NE1094 are 2 parts of a dead gene due to IS element insertion;TonB-dependent receptor protein
228410003904	Transposase domain (DUF772); Region: DUF772; pfam05598
228410003905	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410003906	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
228410003907	ISNE4
228410003908	NE1092 and NE1094 are 2 parts of a dead gene due to IS element insertion;possible TonB-dependent receptor
228410003909	1 probable transmembrane helix predicted by TMHMM2.0
228410003910	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.732 at residue 24
228410003911	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410003912	FecR protein; Region: FecR; pfam04773
228410003913	1 probable transmembrane helix predicted by TMHMM2.0
228410003914	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410003915	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003916	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
228410003917	DNA binding residues [nucleotide binding]
228410003918	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410003919	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
228410003920	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410003921	N-terminal plug; other site
228410003922	ligand-binding site [chemical binding]; other site
228410003923	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.999 at residue 37
228410003924	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410003925	FecR protein; Region: FecR; pfam04773
228410003926	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410003927	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003928	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410003929	DNA binding residues [nucleotide binding]
228410003930	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410003931	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410003932	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410003933	DNA binding residues [nucleotide binding]
228410003934	fec operon regulator FecR; Reviewed; Region: PRK09774
228410003935	FecR protein; Region: FecR; pfam04773
228410003936	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
228410003937	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
228410003938	NE1105 and NE1108 are two parts of a pseudogene caused by the interruption of an IS element
228410003939	Interrupted by IS element, the other part of the gene is NE1108;possible tonB-dependent receptor protein
228410003940	ISNE5
228410003941	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410003942	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410003943	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410003944	Interrupted by IS element, the other part of the gene is NE1105;TonB-dependent receptor protein
228410003945	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
228410003946	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
228410003947	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410003948	non-specific DNA binding site [nucleotide binding]; other site
228410003949	salt bridge; other site
228410003950	sequence-specific DNA binding site [nucleotide binding]; other site
228410003951	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
228410003952	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.971) with cleavage site probability 0.405 at residue 33
228410003953	multidrug efflux protein; Reviewed; Region: PRK09577
228410003954	11 probable transmembrane helices predicted by TMHMM2.0
228410003955	periplasmic multidrug efflux lipoprotein precursor; Reviewed; Region: PRK09578
228410003956	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
228410003957	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410003958	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
228410003959	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
228410003960	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
228410003961	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
228410003962	HlyD family secretion protein; Region: HlyD; pfam00529
228410003963	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410003964	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410003965	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.716) with cleavage site probability 0.282 at residue 25
228410003966	1 probable transmembrane helix predicted by TMHMM2.0
228410003967	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
228410003968	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
228410003969	Walker A/P-loop; other site
228410003970	ATP binding site [chemical binding]; other site
228410003971	Q-loop/lid; other site
228410003972	ABC transporter signature motif; other site
228410003973	Walker B; other site
228410003974	D-loop; other site
228410003975	H-loop/switch region; other site
228410003976	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
228410003977	Walker A/P-loop; other site
228410003978	ATP binding site [chemical binding]; other site
228410003979	Q-loop/lid; other site
228410003980	ABC transporter signature motif; other site
228410003981	Walker B; other site
228410003982	D-loop; other site
228410003983	H-loop/switch region; other site
228410003984	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
228410003985	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
228410003986	5 probable transmembrane helices predicted by TMHMM2.0
228410003987	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
228410003988	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
228410003989	5 probable transmembrane helices predicted by TMHMM2.0
228410003990	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 35
228410003991	1 probable transmembrane helix predicted by TMHMM2.0
228410003992	2 probable transmembrane helices predicted by TMHMM2.0
228410003993	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.938 at residue 31
228410003994	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033
228410003995	putative uracil binding site [chemical binding]; other site
228410003996	putative active site [active]
228410003997	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
228410003998	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
228410003999	active site
228410004000	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.462 at residue 26
228410004001	1 probable transmembrane helix predicted by TMHMM2.0
228410004002	PEP-CTERM-box response regulator transcription factor; Region: PEP_resp_reg; TIGR02915
228410004003	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410004004	active site
228410004005	phosphorylation site [posttranslational modification]
228410004006	intermolecular recognition site; other site
228410004007	dimerization interface [polypeptide binding]; other site
228410004008	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410004009	Walker A motif; other site
228410004010	ATP binding site [chemical binding]; other site
228410004011	Walker B motif; other site
228410004012	arginine finger; other site
228410004013	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
228410004014	acyl-CoA ligase (AMP-forming), exosortase A-associated; Region: ligase_PEP_1; TIGR03098
228410004015	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
228410004016	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_6; cd05922
228410004017	acyl-activating enzyme (AAE) consensus motif; other site
228410004018	acyl-activating enzyme (AAE) consensus motif; other site
228410004019	putative AMP binding site [chemical binding]; other site
228410004020	putative active site [active]
228410004021	putative CoA binding site [chemical binding]; other site
228410004022	pyridoxal-dependent decarboxylase, exosortase A system-associated; Region: dCO2ase_PEP1; TIGR03099
228410004023	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Btrk Decarboxylase; Region: PLPDE_III_Btrk_like; cd06839
228410004024	dimer interface [polypeptide binding]; other site
228410004025	active site
228410004026	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
228410004027	catalytic residues [active]
228410004028	substrate binding site [chemical binding]; other site
228410004029	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
228410004030	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
228410004031	Ligand Binding Site [chemical binding]; other site
228410004032	Molecular Tunnel; other site
228410004033	N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated; Region: exosort_acyl; TIGR03694
228410004034	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.654 at residue 29
228410004035	1 probable transmembrane helix predicted by TMHMM2.0
228410004036	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 30
228410004037	1 probable transmembrane helix predicted by TMHMM2.0
228410004038	NE1131 and NE1134 are two parts of a pseudo gene caused by the insertion of an IS element
228410004039	Interrupted by IS element, the other part of the gene is NE1134;Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF)
228410004040	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.848) with cleavage site probability 0.727 at residue 44
228410004041	3 probable transmembrane helices predicted by TMHMM2.0
228410004042	ISNE6
228410004043	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
228410004044	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410004045	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
228410004046	interrupted by IS element, other part is NE1131;Domain of unknown function 2
228410004047	OsmC-like protein; Region: OsmC; cl00767
228410004048	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
228410004049	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
228410004050	Lipopolysaccharide-assembly; Region: LptE; cl01125
228410004051	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.874) with cleavage site probability 0.325 at residue 26
228410004052	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
228410004053	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
228410004054	HIGH motif; other site
228410004055	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
228410004056	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
228410004057	active site
228410004058	KMSKS motif; other site
228410004059	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
228410004060	tRNA binding surface [nucleotide binding]; other site
228410004061	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
228410004062	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
228410004063	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
228410004064	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
228410004065	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
228410004066	1 probable transmembrane helix predicted by TMHMM2.0
228410004067	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
228410004068	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
228410004069	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
228410004070	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.712) with cleavage site probability 0.479 at residue 30
228410004071	4 probable transmembrane helices predicted by TMHMM2.0
228410004072	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
228410004073	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
228410004074	Protein export membrane protein; Region: SecD_SecF; pfam02355
228410004075	6 probable transmembrane helices predicted by TMHMM2.0
228410004076	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3536
228410004077	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
228410004078	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410004079	S-adenosylmethionine binding site [chemical binding]; other site
228410004080	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
228410004081	agmatinase; Region: agmatinase; TIGR01230
228410004082	oligomer interface [polypeptide binding]; other site
228410004083	putative active site [active]
228410004084	Mn binding site [ion binding]; other site
228410004085	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
228410004086	lipoprotein signal peptidase; Provisional; Region: PRK14787
228410004087	5 probable transmembrane helices predicted by TMHMM2.0
228410004088	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
228410004089	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
228410004090	active site
228410004091	HIGH motif; other site
228410004092	nucleotide binding site [chemical binding]; other site
228410004093	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
228410004094	active site
228410004095	KMSKS motif; other site
228410004096	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
228410004097	tRNA binding surface [nucleotide binding]; other site
228410004098	anticodon binding site; other site
228410004099	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
228410004100	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
228410004101	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
228410004102	active site
228410004103	Riboflavin kinase; Region: Flavokinase; smart00904
228410004104	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
228410004105	apolar tunnel; other site
228410004106	heme binding site [chemical binding]; other site
228410004107	dimerization interface [polypeptide binding]; other site
228410004108	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_18; cd08505
228410004109	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
228410004110	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.981) with cleavage site probability 0.742 at residue 39
228410004111	2 probable transmembrane helices predicted by TMHMM2.0
228410004112	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
228410004113	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410004114	dimer interface [polypeptide binding]; other site
228410004115	conserved gate region; other site
228410004116	putative PBP binding loops; other site
228410004117	ABC-ATPase subunit interface; other site
228410004118	6 probable transmembrane helices predicted by TMHMM2.0
228410004119	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410004120	dimerization interface [polypeptide binding]; other site
228410004121	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
228410004122	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
228410004123	metal binding site [ion binding]; metal-binding site
228410004124	active site
228410004125	I-site; other site
228410004126	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.919) with cleavage site probability 0.622 at residue 34
228410004127	2 probable transmembrane helices predicted by TMHMM2.0
228410004128	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
228410004129	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
228410004130	HSP70 interaction site [polypeptide binding]; other site
228410004131	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
228410004132	substrate binding site [polypeptide binding]; other site
228410004133	dimer interface [polypeptide binding]; other site
228410004134	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
228410004135	Protein of unknown function (DUF2914); Region: DUF2914; pfam11141
228410004136	1 probable transmembrane helix predicted by TMHMM2.0
228410004137	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_4; cd04511
228410004138	nudix motif; other site
228410004139	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
228410004140	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
228410004141	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
228410004142	substrate binding pocket [chemical binding]; other site
228410004143	chain length determination region; other site
228410004144	substrate-Mg2+ binding site; other site
228410004145	catalytic residues [active]
228410004146	aspartate-rich region 1; other site
228410004147	active site lid residues [active]
228410004148	aspartate-rich region 2; other site
228410004149	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
228410004150	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
228410004151	TPP-binding site; other site
228410004152	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
228410004153	PYR/PP interface [polypeptide binding]; other site
228410004154	dimer interface [polypeptide binding]; other site
228410004155	TPP binding site [chemical binding]; other site
228410004156	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
228410004157	putative GTP cyclohydrolase; Provisional; Region: PRK13674
228410004158	hypothetical protein; Provisional; Region: PRK05208
228410004159	4 probable transmembrane helices predicted by TMHMM2.0
228410004160	pteridine reductase; Provisional; Region: PRK09135
228410004161	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
228410004162	NADP binding site [chemical binding]; other site
228410004163	substrate binding pocket [chemical binding]; other site
228410004164	active site
228410004165	Uncharacterized conserved protein [Function unknown]; Region: COG1565
228410004166	hopanoid-associated phosphorylase; Region: HpnG; TIGR03468
228410004167	squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507
228410004168	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
228410004169	Active site cavity [active]
228410004170	catalytic acid [active]
228410004171	VacJ like lipoprotein; Region: VacJ; cl01073
228410004172	1 probable transmembrane helix predicted by TMHMM2.0
228410004173	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
228410004174	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
228410004175	putative NADP binding site [chemical binding]; other site
228410004176	putative substrate binding site [chemical binding]; other site
228410004177	active site
228410004178	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.890) with cleavage site probability 0.640 at residue 23
228410004179	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
228410004180	3 probable transmembrane helices predicted by TMHMM2.0
228410004181	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
228410004182	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
228410004183	generic binding surface II; other site
228410004184	generic binding surface I; other site
228410004185	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
228410004186	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.971) with cleavage site probability 0.602 at residue 27
228410004187	4 probable transmembrane helices predicted by TMHMM2.0
228410004188	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
228410004189	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
228410004190	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
228410004191	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
228410004192	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.555 at residue 25
228410004193	4 probable transmembrane helices predicted by TMHMM2.0
228410004194	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
228410004195	catalytic residue [active]
228410004196	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
228410004197	5' remnant of gene interrupted by an IS element;YER057c/YjgF/UK114 family
228410004198	ISNE1
228410004199	Winged helix-turn helix; Region: HTH_29; pfam13551
228410004200	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410004201	Homeodomain-like domain; Region: HTH_32; pfam13565
228410004202	Integrase core domain; Region: rve; pfam00665
228410004203	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410004204	Integrase core domain; Region: rve_3; pfam13683
228410004205	2 probable transmembrane helices predicted by TMHMM2.0
228410004206	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.600) with cleavage site probability 0.596 at residue 17
228410004207	PemK-like protein; Region: PemK; pfam02452
228410004208	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
228410004209	Peptidase S8 family domain, uncharacterized subfamily 1; Region: Peptidases_S8_1; cd07487
228410004210	active site
228410004211	catalytic triad [active]
228410004212	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
228410004213	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
228410004214	putative acyl-acceptor binding pocket; other site
228410004215	1 probable transmembrane helix predicted by TMHMM2.0
228410004216	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
228410004217	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410004218	active site
228410004219	motif I; other site
228410004220	motif II; other site
228410004221	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
228410004222	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
228410004223	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
228410004224	dimer interface [polypeptide binding]; other site
228410004225	motif 1; other site
228410004226	active site
228410004227	motif 2; other site
228410004228	motif 3; other site
228410004229	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
228410004230	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
228410004231	putative active site [active]
228410004232	catalytic triad [active]
228410004233	putative dimer interface [polypeptide binding]; other site
228410004234	7 probable transmembrane helices predicted by TMHMM2.0
228410004235	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.860) with cleavage site probability 0.271 at residue 23
228410004236	1 probable transmembrane helix predicted by TMHMM2.0
228410004237	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410004238	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
228410004239	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410004240	N-terminal plug; other site
228410004241	ligand-binding site [chemical binding]; other site
228410004242	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 28
228410004243	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410004244	FecR protein; Region: FecR; pfam04773
228410004245	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410004246	RNA polymerase sigma factor; Reviewed; Region: PRK12527
228410004247	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410004248	DNA binding residues [nucleotide binding]
228410004249	NE1193 and an unannotated ORF overlapping the 5' end are 2 parts of a pseudogene caused by a frameshift
228410004250	NE1193 and an unannotated ORF overlapping the 5' end are 2 parts of a dead gene due to a frameshift;similar to S. meliloti suppressor of E.coli rpoH thermosensitive mutation transmembrane protein
228410004251	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.679) with cleavage site probability 0.488 at residue 39
228410004252	1 probable transmembrane helix predicted by TMHMM2.0
228410004253	NnrS protein; Region: NnrS; pfam05940
228410004254	12 probable transmembrane helices predicted by TMHMM2.0
228410004255	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.796) with cleavage site probability 0.580 at residue 35
228410004256	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
228410004257	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
228410004258	Walker A/P-loop; other site
228410004259	ATP binding site [chemical binding]; other site
228410004260	Q-loop/lid; other site
228410004261	ABC transporter signature motif; other site
228410004262	Walker B; other site
228410004263	D-loop; other site
228410004264	H-loop/switch region; other site
228410004265	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
228410004266	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410004267	dimer interface [polypeptide binding]; other site
228410004268	conserved gate region; other site
228410004269	putative PBP binding loops; other site
228410004270	ABC-ATPase subunit interface; other site
228410004271	6 probable transmembrane helices predicted by TMHMM2.0
228410004272	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
228410004273	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 23
228410004274	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
228410004275	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.446 at residue 22
228410004276	5 probable transmembrane helices predicted by TMHMM2.0
228410004277	2 probable transmembrane helices predicted by TMHMM2.0
228410004278	hypothetical protein; Provisional; Region: PRK09272
228410004279	3 probable transmembrane helices predicted by TMHMM2.0
228410004280	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
228410004281	Ligand Binding Site [chemical binding]; other site
228410004282	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
228410004283	Ligand Binding Site [chemical binding]; other site
228410004284	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.976) with cleavage site probability 0.800 at residue 42
228410004285	2 probable transmembrane helices predicted by TMHMM2.0
228410004286	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410004287	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410004288	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410004289	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.971) with cleavage site probability 0.951 at residue 26
228410004290	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.990 at residue 26
228410004291	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
228410004292	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410004293	N-terminal plug; other site
228410004294	ligand-binding site [chemical binding]; other site
228410004295	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.900 at residue 41
228410004296	1 probable transmembrane helix predicted by TMHMM2.0
228410004297	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
228410004298	catalytic residues [active]
228410004299	dimer interface [polypeptide binding]; other site
228410004300	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
228410004301	Gamma carbonic anhydrases (CA): Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed...; Region: LbH_gamma_CA; cd00710
228410004302	trimer interface [polypeptide binding]; other site
228410004303	active site
228410004304	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
228410004305	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410004306	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410004307	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.520 at residue 35
228410004308	1 probable transmembrane helix predicted by TMHMM2.0
228410004309	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
228410004310	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
228410004311	Walker A/P-loop; other site
228410004312	ATP binding site [chemical binding]; other site
228410004313	Q-loop/lid; other site
228410004314	ABC transporter signature motif; other site
228410004315	Walker B; other site
228410004316	D-loop; other site
228410004317	H-loop/switch region; other site
228410004318	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
228410004319	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
228410004320	Walker A/P-loop; other site
228410004321	ATP binding site [chemical binding]; other site
228410004322	Q-loop/lid; other site
228410004323	ABC transporter signature motif; other site
228410004324	Walker B; other site
228410004325	D-loop; other site
228410004326	H-loop/switch region; other site
228410004327	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
228410004328	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
228410004329	7 probable transmembrane helices predicted by TMHMM2.0
228410004330	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
228410004331	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
228410004332	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
228410004333	7 probable transmembrane helices predicted by TMHMM2.0
228410004334	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
228410004335	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
228410004336	putative substrate binding site [chemical binding]; other site
228410004337	putative ATP binding site [chemical binding]; other site
228410004338	sucrose-phosphate synthase, putative, glycosyltransferase domain; Region: sucr_P_syn_N; TIGR02472
228410004339	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
228410004340	putative ADP-binding pocket [chemical binding]; other site
228410004341	sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial; Region: sucr_syn_bact_C; TIGR02471
228410004342	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410004343	active site
228410004344	motif I; other site
228410004345	motif II; other site
228410004346	sucrose synthase; Region: sucr_synth; TIGR02470
228410004347	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
228410004348	putative ADP-binding pocket [chemical binding]; other site
228410004349	short chain dehydrogenase; Provisional; Region: PRK05993
228410004350	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
228410004351	NADP binding site [chemical binding]; other site
228410004352	active site
228410004353	steroid binding site; other site
228410004354	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.823) with cleavage site probability 0.477 at residue 25
228410004355	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
228410004356	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
228410004357	Soluble P-type ATPase [General function prediction only]; Region: COG4087
228410004358	8 probable transmembrane helices predicted by TMHMM2.0
228410004359	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410004360	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
228410004361	fec operon regulator FecR; Reviewed; Region: PRK09774
228410004362	FecR protein; Region: FecR; pfam04773
228410004363	1 probable transmembrane helix predicted by TMHMM2.0
228410004364	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
228410004365	active site
228410004366	DNA polymerase IV; Validated; Region: PRK02406
228410004367	DNA binding site [nucleotide binding]
228410004368	remnant of gene interrupted by an IS element;probable tonB-dependent receptor protein
228410004369	1 probable transmembrane helix predicted by TMHMM2.0
228410004370	ISNE1
228410004371	dead gene the 5' end of the transposon is missing, cut off by another transposon;Integrase, catalytic core
228410004372	ISNE4
228410004373	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410004374	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410004375	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410004376	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
228410004377	ISNE
228410004378	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
228410004379	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
228410004380	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
228410004381	putative active site [active]
228410004382	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
228410004383	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.832 at residue 25
228410004384	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA; cl00391
228410004385	Protein of unknown function (DUF1504); Region: DUF1504; pfam07399
228410004386	12 probable transmembrane helices predicted by TMHMM2.0
228410004387	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.883) with cleavage site probability 0.647 at residue 39
228410004388	peptide chain release factor 2; Validated; Region: prfB; PRK00578
228410004389	This domain is found in peptide chain release factors; Region: PCRF; smart00937
228410004390	RF-1 domain; Region: RF-1; pfam00472
228410004391	Protein of unknown function (DUF1207); Region: DUF1207; pfam06727
228410004392	Protein of unknown function (DUF533); Region: DUF533; pfam04391
228410004393	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
228410004394	putative metal binding site [ion binding]; other site
228410004395	Catalase-like heme-binding proteins similar to the uncharacterized y4iL; Region: y4iL_like; cd08152
228410004396	putative heme binding pocket [chemical binding]; other site
228410004397	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
228410004398	1 probable transmembrane helix predicted by TMHMM2.0
228410004399	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
228410004400	choline dehydrogenase; Validated; Region: PRK02106
228410004401	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
228410004402	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
228410004403	Animal heme peroxidases and related proteins; Region: An_peroxidase_like; cl14561
228410004404	Animal heme oxidases similar to plant pathogen-inducible oxygenases; Region: PIOX_like; cd09818
228410004405	putative heme binding site [chemical binding]; other site
228410004406	putative active site [active]
228410004407	putative substrate binding site [chemical binding]; other site
228410004408	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.751) with cleavage site probability 0.566 at residue 22
228410004409	Lipoxygenase; Region: Lipoxygenase; pfam00305
228410004410	Animal prostaglandin endoperoxide synthase and related bacterial proteins; Region: prostaglandin_endoperoxide_synthase; cd09816
228410004411	substrate binding site [chemical binding]; other site
228410004412	homodimer interface [polypeptide binding]; other site
228410004413	heme binding site [chemical binding]; other site
228410004414	Common central domain of tyrosinase; Region: Tyrosinase; pfam00264
228410004415	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
228410004416	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
228410004417	1 probable transmembrane helix predicted by TMHMM2.0
228410004418	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
228410004419	Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; Region: KAZAL_FS; cd00104
228410004420	1 probable transmembrane helix predicted by TMHMM2.0
228410004421	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
228410004422	this is the remnant of a transposon;transposase
228410004423	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
228410004424	putative binding surface; other site
228410004425	active site
228410004426	Hpt domain; Region: Hpt; pfam01627
228410004427	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
228410004428	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
228410004429	putative binding surface; other site
228410004430	active site
228410004431	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
228410004432	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410004433	ATP binding site [chemical binding]; other site
228410004434	Mg2+ binding site [ion binding]; other site
228410004435	G-X-G motif; other site
228410004436	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
228410004437	Response regulator receiver domain; Region: Response_reg; pfam00072
228410004438	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410004439	active site
228410004440	phosphorylation site [posttranslational modification]
228410004441	intermolecular recognition site; other site
228410004442	dimerization interface [polypeptide binding]; other site
228410004443	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
228410004444	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
228410004445	dimer interface [polypeptide binding]; other site
228410004446	putative CheW interface [polypeptide binding]; other site
228410004447	2 probable transmembrane helices predicted by TMHMM2.0
228410004448	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
228410004449	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
228410004450	1 probable transmembrane helix predicted by TMHMM2.0
228410004451	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
228410004452	1 probable transmembrane helix predicted by TMHMM2.0
228410004453	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.966) with cleavage site probability 0.947 at residue 17
228410004454	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
228410004455	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
228410004456	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.683) with cleavage site probability 0.135 at residue 35
228410004457	1 probable transmembrane helix predicted by TMHMM2.0
228410004458	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
228410004459	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
228410004460	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
228410004461	3 probable transmembrane helices predicted by TMHMM2.0
228410004462	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
228410004463	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
228410004464	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
228410004465	Walker A motif; other site
228410004466	ATP binding site [chemical binding]; other site
228410004467	Walker B motif; other site
228410004468	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
228410004469	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
228410004470	ParB-like nuclease domain; Region: ParB; smart00470
228410004471	ISNE3
228410004472	putative transposase OrfB; Reviewed; Region: PHA02517
228410004473	HTH-like domain; Region: HTH_21; pfam13276
228410004474	Integrase core domain; Region: rve; pfam00665
228410004475	Integrase core domain; Region: rve_3; pfam13683
228410004476	5' end removed by IS element;ATPase components of ABC transporters with duplicated ATPase domains
228410004477	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
228410004478	ISNE1
228410004479	Winged helix-turn helix; Region: HTH_29; pfam13551
228410004480	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410004481	Homeodomain-like domain; Region: HTH_32; pfam13565
228410004482	Integrase core domain; Region: rve; pfam00665
228410004483	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410004484	Integrase core domain; Region: rve_3; pfam13683
228410004485	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
228410004486	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
228410004487	Coenzyme A binding pocket [chemical binding]; other site
228410004488	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
228410004489	gene remnant;conserved hypothetical protein
228410004490	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
228410004491	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
228410004492	ISNE3
228410004493	putative transposase OrfB; Reviewed; Region: PHA02517
228410004494	HTH-like domain; Region: HTH_21; pfam13276
228410004495	Integrase core domain; Region: rve; pfam00665
228410004496	Integrase core domain; Region: rve_3; pfam13683
228410004497	3' remnant of gene interrupted by an IS element; serine protease protein
228410004498	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
228410004499	HI0933-like protein; Region: HI0933_like; pfam03486
228410004500	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
228410004501	Cytochrome c; Region: Cytochrom_C; pfam00034
228410004502	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 28
228410004503	1 probable transmembrane helix predicted by TMHMM2.0
228410004504	1 probable transmembrane helix predicted by TMHMM2.0
228410004505	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.739) with cleavage site probability 0.372 at residue 32
228410004506	DoxX; Region: DoxX; pfam07681
228410004507	4 probable transmembrane helices predicted by TMHMM2.0
228410004508	3 probable transmembrane helices predicted by TMHMM2.0
228410004509	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
228410004510	Found in ATP-dependent protease La (LON); Region: LON; smart00464
228410004511	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410004512	Walker A motif; other site
228410004513	ATP binding site [chemical binding]; other site
228410004514	Walker B motif; other site
228410004515	arginine finger; other site
228410004516	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
228410004517	1 probable transmembrane helix predicted by TMHMM2.0
228410004518	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.961 at residue 21
228410004519	1 probable transmembrane helix predicted by TMHMM2.0
228410004520	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
228410004521	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
228410004522	GDP-binding site [chemical binding]; other site
228410004523	ACT binding site; other site
228410004524	IMP binding site; other site
228410004525	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: PRK12421
228410004526	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
228410004527	dimer interface [polypeptide binding]; other site
228410004528	motif 1; other site
228410004529	active site
228410004530	motif 2; other site
228410004531	motif 3; other site
228410004532	Uncharacterized protein conserved in bacteria (DUF2065); Region: DUF2065; pfam09838
228410004533	2 probable transmembrane helices predicted by TMHMM2.0
228410004534	HflC protein; Region: hflC; TIGR01932
228410004535	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
228410004536	1 probable transmembrane helix predicted by TMHMM2.0
228410004537	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.977) with cleavage site probability 0.412 at residue 23
228410004538	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
228410004539	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
228410004540	HflK protein; Region: hflK; TIGR01933
228410004541	1 probable transmembrane helix predicted by TMHMM2.0
228410004542	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
228410004543	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
228410004544	HflX GTPase family; Region: HflX; cd01878
228410004545	G1 box; other site
228410004546	GTP/Mg2+ binding site [chemical binding]; other site
228410004547	Switch I region; other site
228410004548	G2 box; other site
228410004549	G3 box; other site
228410004550	Switch II region; other site
228410004551	G4 box; other site
228410004552	G5 box; other site
228410004553	bacterial Hfq-like; Region: Hfq; cd01716
228410004554	hexamer interface [polypeptide binding]; other site
228410004555	Sm1 motif; other site
228410004556	RNA binding site [nucleotide binding]; other site
228410004557	Sm2 motif; other site
228410004558	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
228410004559	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
228410004560	PAS domain; Region: PAS_8; pfam13188
228410004561	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410004562	dimer interface [polypeptide binding]; other site
228410004563	phosphorylation site [posttranslational modification]
228410004564	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410004565	ATP binding site [chemical binding]; other site
228410004566	Mg2+ binding site [ion binding]; other site
228410004567	G-X-G motif; other site
228410004568	2 probable transmembrane helices predicted by TMHMM2.0
228410004569	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
228410004570	gamma-glutamyl kinase; Provisional; Region: PRK05429
228410004571	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
228410004572	nucleotide binding site [chemical binding]; other site
228410004573	homotetrameric interface [polypeptide binding]; other site
228410004574	putative phosphate binding site [ion binding]; other site
228410004575	putative allosteric binding site; other site
228410004576	PUA domain; Region: PUA; pfam01472
228410004577	GTPase CgtA; Reviewed; Region: obgE; PRK12299
228410004578	GTP1/OBG; Region: GTP1_OBG; pfam01018
228410004579	Obg GTPase; Region: Obg; cd01898
228410004580	G1 box; other site
228410004581	GTP/Mg2+ binding site [chemical binding]; other site
228410004582	Switch I region; other site
228410004583	G2 box; other site
228410004584	G3 box; other site
228410004585	Switch II region; other site
228410004586	G4 box; other site
228410004587	G5 box; other site
228410004588	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
228410004589	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
228410004590	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
228410004591	glutamate--cysteine ligase, T. ferrooxidans family; Region: gshA_ferroox; TIGR02049
228410004592	Glutamate-cysteine ligase; Region: GshA; pfam08886
228410004593	glutathione synthetase; Provisional; Region: PRK05246
228410004594	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
228410004595	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
228410004596	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
228410004597	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
228410004598	ligand binding site [chemical binding]; other site
228410004599	flexible hinge region; other site
228410004600	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
228410004601	1 probable transmembrane helix predicted by TMHMM2.0
228410004602	FecR protein; Region: FecR; pfam04773
228410004603	Tetratricopeptide repeat; Region: TPR_16; pfam13432
228410004604	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410004605	TPR motif; other site
228410004606	TPR repeat; Region: TPR_11; pfam13414
228410004607	binding surface
228410004608	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410004609	binding surface
228410004610	Tetratricopeptide repeat; Region: TPR_16; pfam13432
228410004611	TPR motif; other site
228410004612	TPR repeat; Region: TPR_11; pfam13414
228410004613	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
228410004614	1 probable transmembrane helix predicted by TMHMM2.0
228410004615	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
228410004616	CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria; Region: CHASE2; smart01080
228410004617	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
228410004618	cyclase homology domain; Region: CHD; cd07302
228410004619	nucleotidyl binding site; other site
228410004620	metal binding site [ion binding]; metal-binding site
228410004621	dimer interface [polypeptide binding]; other site
228410004622	4 probable transmembrane helices predicted by TMHMM2.0
228410004623	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.629 at residue 30
228410004624	1 probable transmembrane helix predicted by TMHMM2.0
228410004625	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.974 at residue 23
228410004626	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
228410004627	3 probable transmembrane helices predicted by TMHMM2.0
228410004628	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
228410004629	Family description; Region: VCBS; pfam13517
228410004630	LppP/LprE lipoprotein; Region: Lipoprotein_21; pfam14041
228410004631	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 at residue 25
228410004632	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410004633	non-specific DNA binding site [nucleotide binding]; other site
228410004634	salt bridge; other site
228410004635	sequence-specific DNA binding site [nucleotide binding]; other site
228410004636	Plasmid maintenance system killer protein; Region: Plasmid_killer; pfam05015
228410004637	PemK-like protein; Region: PemK; pfam02452
228410004638	Protein of unknown function (DUF3018); Region: DUF3018; pfam11455
228410004639	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
228410004640	Pilin (bacterial filament); Region: Pilin; pfam00114
228410004641	1 probable transmembrane helix predicted by TMHMM2.0
228410004642	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.810) with cleavage site probability 0.396 at residue 28
228410004643	Predicted membrane protein (DUF2335); Region: DUF2335; pfam10097
228410004644	HipA N-terminal domain; Region: couple_hipA; TIGR03071
228410004645	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
228410004646	HipA-like N-terminal domain; Region: HipA_N; pfam07805
228410004647	HipA-like C-terminal domain; Region: HipA_C; pfam07804
228410004648	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410004649	non-specific DNA binding site [nucleotide binding]; other site
228410004650	salt bridge; other site
228410004651	sequence-specific DNA binding site [nucleotide binding]; other site
228410004652	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
228410004653	DNA-binding site [nucleotide binding]; DNA binding site
228410004654	RNA-binding motif; other site
228410004655	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain [Signal transduction mechanisms / Transcription]; Region: COG4567
228410004656	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410004657	active site
228410004658	phosphorylation site [posttranslational modification]
228410004659	intermolecular recognition site; other site
228410004660	dimerization interface [polypeptide binding]; other site
228410004661	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
228410004662	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
228410004663	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410004664	ATP binding site [chemical binding]; other site
228410004665	G-X-G motif; other site
228410004666	5 probable transmembrane helices predicted by TMHMM2.0
228410004667	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
228410004668	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
228410004669	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 at residue 27
228410004670	1 probable transmembrane helix predicted by TMHMM2.0
228410004671	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
228410004672	putative active site [active]
228410004673	Ap4A binding site [chemical binding]; other site
228410004674	nudix motif; other site
228410004675	putative metal binding site [ion binding]; other site
228410004676	prolyl-tRNA synthetase; Provisional; Region: PRK09194
228410004677	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
228410004678	dimer interface [polypeptide binding]; other site
228410004679	motif 1; other site
228410004680	active site
228410004681	motif 2; other site
228410004682	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
228410004683	putative deacylase active site [active]
228410004684	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
228410004685	active site
228410004686	motif 3; other site
228410004687	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
228410004688	anticodon binding site; other site
228410004689	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
228410004690	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
228410004691	N-acetyl-D-glucosamine binding site [chemical binding]; other site
228410004692	catalytic residue [active]
228410004693	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.883 at residue 19
228410004694	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
228410004695	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
228410004696	catalytic residues [active]
228410004697	1 probable transmembrane helix predicted by TMHMM2.0
228410004698	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.975) with cleavage site probability 0.610 at residue 21
228410004699	2-isopropylmalate synthase; Validated; Region: PRK00915
228410004700	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
228410004701	active site
228410004702	catalytic residues [active]
228410004703	metal binding site [ion binding]; metal-binding site
228410004704	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
228410004705	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
228410004706	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
228410004707	6 probable transmembrane helices predicted by TMHMM2.0
228410004708	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
228410004709	1 probable transmembrane helix predicted by TMHMM2.0
228410004710	ketol-acid reductoisomerase; Provisional; Region: PRK05479
228410004711	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
228410004712	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
228410004713	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
228410004714	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
228410004715	putative valine binding site [chemical binding]; other site
228410004716	dimer interface [polypeptide binding]; other site
228410004717	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
228410004718	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK06965
228410004719	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
228410004720	PYR/PP interface [polypeptide binding]; other site
228410004721	dimer interface [polypeptide binding]; other site
228410004722	TPP binding site [chemical binding]; other site
228410004723	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
228410004724	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
228410004725	TPP-binding site [chemical binding]; other site
228410004726	dimer interface [polypeptide binding]; other site
228410004727	protease TldD; Provisional; Region: tldD; PRK10735
228410004728	nitrilase; Region: PLN02798
228410004729	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
228410004730	putative active site [active]
228410004731	catalytic triad [active]
228410004732	dimer interface [polypeptide binding]; other site
228410004733	TIGR02099 family protein; Region: TIGR02099
228410004734	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
228410004735	1 probable transmembrane helix predicted by TMHMM2.0
228410004736	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
228410004737	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
228410004738	metal binding triad; other site
228410004739	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
228410004740	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
228410004741	metal binding triad; other site
228410004742	Fatty acid cis/trans isomerase (CTI); Region: CTI; pfam06934
228410004743	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
228410004744	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
228410004745	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.459 at residue 23
228410004746	Sulfatase; Region: Sulfatase; cl17466
228410004747	5 probable transmembrane helices predicted by TMHMM2.0
228410004748	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
228410004749	NAD(P) binding site [chemical binding]; other site
228410004750	active site
228410004751	1 probable transmembrane helix predicted by TMHMM2.0
228410004752	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.978 at residue 27
228410004753	Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex; Region: CESA_CaSu_A2; cd06437
228410004754	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
228410004755	DXD motif; other site
228410004756	6 probable transmembrane helices predicted by TMHMM2.0
228410004757	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
228410004758	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
228410004759	PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family; Region: stp3; TIGR04063
228410004760	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u9; cd10933
228410004761	putative active site [active]
228410004762	putative catalytic site [active]
228410004763	H-NS histone family; Region: Histone_HNS; pfam00816
228410004764	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
228410004765	H-NS histone family; Region: Histone_HNS; pfam00816
228410004766	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
228410004767	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
228410004768	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
228410004769	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
228410004770	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
228410004771	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
228410004772	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.630) with cleavage site probability 0.465 at residue 29
228410004773	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
228410004774	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
228410004775	ISNE1
228410004776	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410004777	Winged helix-turn helix; Region: HTH_29; pfam13551
228410004778	Homeodomain-like domain; Region: HTH_32; pfam13565
228410004779	Integrase core domain; Region: rve; pfam00665
228410004780	Integrase core domain; Region: rve_3; pfam13683
228410004781	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
228410004782	putative active site [active]
228410004783	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
228410004784	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
228410004785	ISNE1
228410004786	Winged helix-turn helix; Region: HTH_29; pfam13551
228410004787	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410004788	Homeodomain-like domain; Region: HTH_32; pfam13565
228410004789	Integrase core domain; Region: rve; pfam00665
228410004790	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410004791	Integrase core domain; Region: rve_3; pfam13683
228410004792	toxin-antitoxin system, toxin component, Txe/YoeB family; Region: toxin_Txe_YoeB; TIGR02116
228410004793	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
228410004794	Helix-turn-helix domain; Region: HTH_37; pfam13744
228410004795	non-specific DNA binding site [nucleotide binding]; other site
228410004796	salt bridge; other site
228410004797	sequence-specific DNA binding site [nucleotide binding]; other site
228410004798	probable addiction module antidote protein; Region: dnstrm_HI1420; TIGR02684
228410004799	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
228410004800	NE1358 and NE1359 are 2 parts of a pseudogene caused by a frameshift
228410004801	NE1358 and NE1359 are 2 parts of a dead gene due to a frameshift;hypothetical protein
228410004802	NE1358 and NE1359 are 2 parts of a dead gene due to a frameshift;conserved hypothetical protein
228410004803	RloB-like protein; Region: RloB; pfam13707
228410004804	Predicted ATPases [General function prediction only]; Region: COG1106
228410004805	Macro domain, Poa1p_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Poa1p_like; cd02901
228410004806	ADP-ribose binding site [chemical binding]; other site
228410004807	Protein of unknown function (DUF4065); Region: DUF4065; cl01445
228410004808	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
228410004809	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410004810	sequence-specific DNA binding site [nucleotide binding]; other site
228410004811	salt bridge; other site
228410004812	ISNE1
228410004813	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410004814	Winged helix-turn helix; Region: HTH_29; pfam13551
228410004815	Homeodomain-like domain; Region: HTH_32; pfam13565
228410004816	Integrase core domain; Region: rve_3; pfam13683
228410004817	remnant of gene interrupted by IS element;possible glycosyltransferase
228410004818	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
228410004819	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
228410004820	active site
228410004821	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
228410004822	active site
228410004823	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
228410004824	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
228410004825	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
228410004826	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410004827	non-specific DNA binding site [nucleotide binding]; other site
228410004828	salt bridge; other site
228410004829	sequence-specific DNA binding site [nucleotide binding]; other site
228410004830	PIN domains of VapC and Smg6 ribonucleases, ribosome assembly factor NOB1, Archaeoglobus fulgidus AF0591 protein and homologs; Region: PIN_VapC-Smg6-like; cd09855
228410004831	putative active site [active]
228410004832	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
228410004833	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410004834	non-specific DNA binding site [nucleotide binding]; other site
228410004835	salt bridge; other site
228410004836	sequence-specific DNA binding site [nucleotide binding]; other site
228410004837	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
228410004838	PIN domain; Region: PIN_3; cl17397
228410004839	ISNE1
228410004840	Winged helix-turn helix; Region: HTH_29; pfam13551
228410004841	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410004842	Homeodomain-like domain; Region: HTH_32; pfam13565
228410004843	Integrase core domain; Region: rve; pfam00665
228410004844	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410004845	Integrase core domain; Region: rve_3; pfam13683
228410004846	1 probable transmembrane helix predicted by TMHMM2.0
228410004847	Domain of unknown function (DUF4325); Region: DUF4325; pfam14213
228410004848	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
228410004849	UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: GalU; COG1210
228410004850	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
228410004851	active site
228410004852	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.786) with cleavage site probability 0.644 at residue 23
228410004853	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
228410004854	2 probable transmembrane helices predicted by TMHMM2.0
228410004855	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
228410004856	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
228410004857	Walker A/P-loop; other site
228410004858	ATP binding site [chemical binding]; other site
228410004859	Q-loop/lid; other site
228410004860	ABC transporter signature motif; other site
228410004861	Walker B; other site
228410004862	D-loop; other site
228410004863	H-loop/switch region; other site
228410004864	ABC-2 type transporter; Region: ABC2_membrane; cl17235
228410004865	6 probable transmembrane helices predicted by TMHMM2.0
228410004866	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
228410004867	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
228410004868	1 probable transmembrane helix predicted by TMHMM2.0
228410004869	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.576 at residue 28
228410004870	hypothetical protein; Provisional; Region: PRK07505
228410004871	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
228410004872	substrate-cofactor binding pocket; other site
228410004873	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410004874	catalytic residue [active]
228410004875	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
228410004876	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
228410004877	active site
228410004878	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
228410004879	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
228410004880	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
228410004881	enoyl reductase of polyketide synthase; Region: enoyl_red; cd05195
228410004882	Enoylreductase; Region: PKS_ER; smart00829
228410004883	NAD(P) binding site [chemical binding]; other site
228410004884	beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 2, complex (x); Region: KR_2_FAS_SDR_x; cd08955
228410004885	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
228410004886	putative NADP binding site [chemical binding]; other site
228410004887	active site
228410004888	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
228410004889	exonuclease subunit SbcD; Provisional; Region: PRK10966
228410004890	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
228410004891	active site
228410004892	metal binding site [ion binding]; metal-binding site
228410004893	DNA binding site [nucleotide binding]
228410004894	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
228410004895	The other half of this pseudogene is modeled as NE2120 at position 2300508..2301302;Esterase/lipase/thioesterase family active site
228410004896	exonuclease subunit SbcC; Provisional; Region: PRK10246
228410004897	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410004898	Walker A/P-loop; other site
228410004899	ATP binding site [chemical binding]; other site
228410004900	Q-loop/lid; other site
228410004901	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
228410004902	ABC transporter signature motif; other site
228410004903	Walker B; other site
228410004904	D-loop; other site
228410004905	H-loop/switch region; other site
228410004906	NE1393 and NE1394 are 2 parts of a pseudogene caused by a premature stop codons
228410004907	pseudogene, contains a premature stop codon, the other half of the gene is NE1394; protein
228410004908	pseudogene, contains a premature stop codon, the other half of the gene is NE1393;possible TodX protein
228410004909	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.964) with cleavage site probability 0.960 at residue 25
228410004910	NE1395 and NE1396 are 2 parts of a pseudogene caused by a frameshift
228410004911	dead gene due to frameshift; this gene contains only 1 PAS & 1 PAC domain and nothing else; it seems to be the 5' of NE1396 which also contains PAS and PAC domains plus a signal transducer;PAS domain:PAC motif
228410004912	dead gene due to framehsift; the other part of the gene is NE1395;Methyl-accepting chemotaxis protein
228410004913	CheW-like domain; Region: CheW; pfam01584
228410004914	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
228410004915	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
228410004916	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
228410004917	Fe-S cluster binding site [ion binding]; other site
228410004918	active site
228410004919	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
228410004920	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
228410004921	Coenzyme A binding pocket [chemical binding]; other site
228410004922	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
228410004923	Glycoprotease family; Region: Peptidase_M22; pfam00814
228410004924	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
228410004925	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
228410004926	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
228410004927	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
228410004928	homotrimer interaction site [polypeptide binding]; other site
228410004929	zinc binding site [ion binding]; other site
228410004930	CDP-binding sites; other site
228410004931	Uncharacterized conserved protein [Function unknown]; Region: COG3189
228410004932	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
228410004933	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
228410004934	Walker A/P-loop; other site
228410004935	ATP binding site [chemical binding]; other site
228410004936	Q-loop/lid; other site
228410004937	ABC transporter signature motif; other site
228410004938	Walker B; other site
228410004939	D-loop; other site
228410004940	H-loop/switch region; other site
228410004941	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410004942	FtsX-like permease family; Region: FtsX; pfam02687
228410004943	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
228410004944	FtsX-like permease family; Region: FtsX; pfam02687
228410004945	10 probable transmembrane helices predicted by TMHMM2.0
228410004946	Hydroxyneurosporene synthase (CrtC); Region: CrtC; pfam07143
228410004947	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.931) with cleavage site probability 0.725 at residue 26
228410004948	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
228410004949	CPxP  motif; other site
228410004950	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
228410004951	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410004952	dimer interface [polypeptide binding]; other site
228410004953	phosphorylation site [posttranslational modification]
228410004954	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410004955	ATP binding site [chemical binding]; other site
228410004956	Mg2+ binding site [ion binding]; other site
228410004957	G-X-G motif; other site
228410004958	2 probable transmembrane helices predicted by TMHMM2.0
228410004959	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.934 at residue 27
228410004960	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
228410004961	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410004962	active site
228410004963	phosphorylation site [posttranslational modification]
228410004964	intermolecular recognition site; other site
228410004965	dimerization interface [polypeptide binding]; other site
228410004966	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
228410004967	DNA binding site [nucleotide binding]
228410004968	Predicted membrane protein [Function unknown]; Region: COG3212
228410004969	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
228410004970	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.886) with cleavage site probability 0.367 at residue 18
228410004971	methane monooxygenase/ammonia monooxygenase, subunit C; Region: CH4_NH3mon_ox_C; TIGR03078
228410004972	6 probable transmembrane helices predicted by TMHMM2.0
228410004973	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
228410004974	substrate binding site; other site
228410004975	dimer interface; other site
228410004976	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.748) with cleavage site probability 0.747 at residue 19
228410004977	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
228410004978	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
228410004979	4 probable transmembrane helices predicted by TMHMM2.0
228410004980	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
228410004981	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410004982	Walker A/P-loop; other site
228410004983	ATP binding site [chemical binding]; other site
228410004984	Q-loop/lid; other site
228410004985	ABC transporter signature motif; other site
228410004986	Walker B; other site
228410004987	D-loop; other site
228410004988	H-loop/switch region; other site
228410004989	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
228410004990	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
228410004991	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
228410004992	P loop; other site
228410004993	GTP binding site [chemical binding]; other site
228410004994	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
228410004995	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
228410004996	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
228410004997	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.767 at residue 27
228410004998	alanine racemase; Reviewed; Region: alr; PRK00053
228410004999	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
228410005000	active site
228410005001	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
228410005002	substrate binding site [chemical binding]; other site
228410005003	catalytic residues [active]
228410005004	dimer interface [polypeptide binding]; other site
228410005005	peptidyl-prolyl cis-trans isomerase, EpsD family; Region: cis_trans_EpsD; TIGR02925
228410005006	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
228410005007	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.795 at residue 25
228410005008	YciI-like protein; Reviewed; Region: PRK11370
228410005009	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
228410005010	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
228410005011	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410005012	heat shock protein HtpX; Provisional; Region: PRK05457
228410005013	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.946) with cleavage site probability 0.883 at residue 28
228410005014	4 probable transmembrane helices predicted by TMHMM2.0
228410005015	VacJ like lipoprotein; Region: VacJ; cl01073
228410005016	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.985) with cleavage site probability 0.658 at residue 26
228410005017	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
228410005018	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
228410005019	inhibitor-cofactor binding pocket; inhibition site
228410005020	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410005021	catalytic residue [active]
228410005022	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
228410005023	thiamine phosphate binding site [chemical binding]; other site
228410005024	active site
228410005025	pyrophosphate binding site [ion binding]; other site
228410005026	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
228410005027	dimer interface [polypeptide binding]; other site
228410005028	substrate binding site [chemical binding]; other site
228410005029	ATP binding site [chemical binding]; other site
228410005030	Rubredoxin [Energy production and conversion]; Region: COG1773
228410005031	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
228410005032	iron binding site [ion binding]; other site
228410005033	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
228410005034	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
228410005035	dimer interface [polypeptide binding]; other site
228410005036	active site
228410005037	metal binding site [ion binding]; metal-binding site
228410005038	glutathione binding site [chemical binding]; other site
228410005039	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
228410005040	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
228410005041	putative peptidase; Provisional; Region: PRK11649
228410005042	Peptidase family M23; Region: Peptidase_M23; pfam01551
228410005043	1 probable transmembrane helix predicted by TMHMM2.0
228410005044	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.899) with cleavage site probability 0.726 at residue 46
228410005045	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
228410005046	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
228410005047	active site
228410005048	HIGH motif; other site
228410005049	dimer interface [polypeptide binding]; other site
228410005050	KMSKS motif; other site
228410005051	S4 RNA-binding domain; Region: S4; smart00363
228410005052	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
228410005053	ATP cone domain; Region: ATP-cone; pfam03477
228410005054	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
228410005055	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
228410005056	dimer interface [polypeptide binding]; other site
228410005057	active site
228410005058	glycine-pyridoxal phosphate binding site [chemical binding]; other site
228410005059	folate binding site [chemical binding]; other site
228410005060	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
228410005061	Transcriptional regulator [Transcription]; Region: LysR; COG0583
228410005062	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
228410005063	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
228410005064	putative dimerization interface [polypeptide binding]; other site
228410005065	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
228410005066	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
228410005067	THF binding site; other site
228410005068	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
228410005069	substrate binding site [chemical binding]; other site
228410005070	THF binding site; other site
228410005071	zinc-binding site [ion binding]; other site
228410005072	argininosuccinate synthase; Provisional; Region: PRK13820
228410005073	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
228410005074	ANP binding site [chemical binding]; other site
228410005075	Substrate Binding Site II [chemical binding]; other site
228410005076	Substrate Binding Site I [chemical binding]; other site
228410005077	ornithine carbamoyltransferase; Provisional; Region: PRK00779
228410005078	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
228410005079	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
228410005080	acetylornithine aminotransferase; Provisional; Region: PRK02627
228410005081	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
228410005082	inhibitor-cofactor binding pocket; inhibition site
228410005083	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410005084	catalytic residue [active]
228410005085	Protein of unknown function (DUF1318); Region: DUF1318; cl01547
228410005086	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 at residue 26
228410005087	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.908 at residue 35
228410005088	1 probable transmembrane helix predicted by TMHMM2.0
228410005089	1 probable transmembrane helix predicted by TMHMM2.0
228410005090	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.952) with cleavage site probability 0.951 at residue 40
228410005091	cysteine synthase B; Region: cysM; TIGR01138
228410005092	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
228410005093	dimer interface [polypeptide binding]; other site
228410005094	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410005095	catalytic residue [active]
228410005096	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
228410005097	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005098	binding surface
228410005099	TPR motif; other site
228410005100	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005101	binding surface
228410005102	TPR motif; other site
228410005103	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005104	TPR motif; other site
228410005105	binding surface
228410005106	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005107	binding surface
228410005108	TPR motif; other site
228410005109	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005110	binding surface
228410005111	TPR motif; other site
228410005112	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005113	binding surface
228410005114	TPR motif; other site
228410005115	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005116	binding surface
228410005117	TPR motif; other site
228410005118	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005119	binding surface
228410005120	TPR motif; other site
228410005121	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.958) with cleavage site probability 0.320 at residue 32
228410005122	1 probable transmembrane helix predicted by TMHMM2.0
228410005123	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
228410005124	NifU-like domain; Region: NifU; cl00484
228410005125	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
228410005126	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
228410005127	trimerization site [polypeptide binding]; other site
228410005128	active site
228410005129	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
228410005130	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
228410005131	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
228410005132	catalytic residue [active]
228410005133	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
228410005134	FeS assembly protein SufD; Region: sufD; TIGR01981
228410005135	sulfate ABC transporter protein; Validated; Region: ycf16; CHL00131
228410005136	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
228410005137	Walker A/P-loop; other site
228410005138	ATP binding site [chemical binding]; other site
228410005139	Q-loop/lid; other site
228410005140	ABC transporter signature motif; other site
228410005141	Walker B; other site
228410005142	D-loop; other site
228410005143	H-loop/switch region; other site
228410005144	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
228410005145	putative ABC transporter; Region: ycf24; CHL00085
228410005146	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
228410005147	iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010
228410005148	Rrf2 family protein; Region: rrf2_super; TIGR00738
228410005149	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
228410005150	FtsX-like permease family; Region: FtsX; pfam02687
228410005151	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
228410005152	10 probable transmembrane helices predicted by TMHMM2.0
228410005153	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG4181
228410005154	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
228410005155	Walker A/P-loop; other site
228410005156	ATP binding site [chemical binding]; other site
228410005157	Q-loop/lid; other site
228410005158	ABC transporter signature motif; other site
228410005159	Walker B; other site
228410005160	D-loop; other site
228410005161	H-loop/switch region; other site
228410005162	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
228410005163	active site
228410005164	catalytic triad [active]
228410005165	oxyanion hole [active]
228410005166	switch loop; other site
228410005167	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.910 at residue 23
228410005168	1 probable transmembrane helix predicted by TMHMM2.0
228410005169	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
228410005170	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
228410005171	RNA binding surface [nucleotide binding]; other site
228410005172	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
228410005173	active site
228410005174	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
228410005175	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
228410005176	homodimer interface [polypeptide binding]; other site
228410005177	oligonucleotide binding site [chemical binding]; other site
228410005178	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
228410005179	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
228410005180	active site
228410005181	Int/Topo IB signature motif; other site
228410005182	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
228410005183	8 probable transmembrane helices predicted by TMHMM2.0
228410005184	signal recognition particle protein; Provisional; Region: PRK10867
228410005185	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
228410005186	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
228410005187	P loop; other site
228410005188	GTP binding site [chemical binding]; other site
228410005189	Signal peptide binding domain; Region: SRP_SPB; pfam02978
228410005190	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
228410005191	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.947 at residue 22
228410005192	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
228410005193	trimer interface [polypeptide binding]; other site
228410005194	active site
228410005195	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
228410005196	Flavoprotein; Region: Flavoprotein; pfam02441
228410005197	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
228410005198	hypothetical protein; Reviewed; Region: PRK00024
228410005199	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
228410005200	MPN+ (JAMM) motif; other site
228410005201	Zinc-binding site [ion binding]; other site
228410005202	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
228410005203	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
228410005204	Fatty acid desaturase; Region: FA_desaturase; pfam00487
228410005205	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
228410005206	Di-iron ligands [ion binding]; other site
228410005207	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
228410005208	Transposase; Region: DDE_Tnp_ISL3; pfam01610
228410005209	3 probable transmembrane helices predicted by TMHMM2.0
228410005210	DNA polymerase I; Provisional; Region: PRK05755
228410005211	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
228410005212	active site
228410005213	metal binding site 1 [ion binding]; metal-binding site
228410005214	putative 5' ssDNA interaction site; other site
228410005215	metal binding site 3; metal-binding site
228410005216	metal binding site 2 [ion binding]; metal-binding site
228410005217	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
228410005218	putative DNA binding site [nucleotide binding]; other site
228410005219	putative metal binding site [ion binding]; other site
228410005220	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
228410005221	active site
228410005222	catalytic site [active]
228410005223	substrate binding site [chemical binding]; other site
228410005224	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
228410005225	active site
228410005226	DNA binding site [nucleotide binding]
228410005227	catalytic site [active]
228410005228	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
228410005229	Protein of unknown function (DUF2782); Region: DUF2782; pfam11191
228410005230	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.998 at residue 23
228410005231	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
228410005232	Homoserine Kinase, type II. Homoserine kinase is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; Region: HomoserineK_II; cd05153
228410005233	putative active site [active]
228410005234	putative substrate binding site [chemical binding]; other site
228410005235	ATP binding site [chemical binding]; other site
228410005236	6 probable transmembrane helices predicted by TMHMM2.0
228410005237	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
228410005238	Part of AAA domain; Region: AAA_19; pfam13245
228410005239	Family description; Region: UvrD_C_2; pfam13538
228410005240	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
228410005241	active site
228410005242	Peptidase family M48; Region: Peptidase_M48; pfam01435
228410005243	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.656 at residue 23
228410005244	ferrochelatase; Reviewed; Region: hemH; PRK00035
228410005245	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
228410005246	C-terminal domain interface [polypeptide binding]; other site
228410005247	active site
228410005248	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
228410005249	active site
228410005250	N-terminal domain interface [polypeptide binding]; other site
228410005251	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
228410005252	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
228410005253	NAD(+)/NADH kinase family protein; Provisional; Region: ppnK; PRK02155
228410005254	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
228410005255	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
228410005256	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
228410005257	Walker A/P-loop; other site
228410005258	ATP binding site [chemical binding]; other site
228410005259	Q-loop/lid; other site
228410005260	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
228410005261	ABC transporter signature motif; other site
228410005262	Walker B; other site
228410005263	D-loop; other site
228410005264	H-loop/switch region; other site
228410005265	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
228410005266	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
228410005267	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.894 at residue 51
228410005268	1 probable transmembrane helix predicted by TMHMM2.0
228410005269	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
228410005270	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
228410005271	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
228410005272	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
228410005273	23S rRNA interface [nucleotide binding]; other site
228410005274	L3 interface [polypeptide binding]; other site
228410005275	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
228410005276	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
228410005277	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
228410005278	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 at residue 32
228410005279	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
228410005280	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
228410005281	homodimer interface [polypeptide binding]; other site
228410005282	substrate-cofactor binding pocket; other site
228410005283	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410005284	catalytic residue [active]
228410005285	Protein of unknown function (DUF493); Region: DUF493; pfam04359
228410005286	lipoate-protein ligase B; Provisional; Region: PRK14342
228410005287	lipoyl synthase; Provisional; Region: PRK05481
228410005288	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410005289	FeS/SAM binding site; other site
228410005290	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
228410005291	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
228410005292	Ligand Binding Site [chemical binding]; other site
228410005293	Uncharacterized copper-binding protein [Inorganic ion transport and metabolism]; Region: COG4454
228410005294	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.646 at residue 26
228410005295	Predicted metal-binding protein [General function prediction only]; Region: COG3019
228410005296	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.850 at residue 28
228410005297	cytochrome c-550; Provisional; Region: psbV; cl17239
228410005298	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
228410005299	Cytochrome c; Region: Cytochrom_C; pfam00034
228410005300	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.895) with cleavage site probability 0.561 at residue 23
228410005301	CHAD domain; Region: CHAD; pfam05235
228410005302	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
228410005303	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
228410005304	P-loop; other site
228410005305	Magnesium ion binding site [ion binding]; other site
228410005306	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
228410005307	Magnesium ion binding site [ion binding]; other site
228410005308	Clostridium thermocellum (Cth)TTM and similar proteins, a subgroup of the CYTH-like superfamily; Region: CYTH-like_CthTTM-like; cd07761
228410005309	putative active site [active]
228410005310	putative metal binding residues [ion binding]; other site
228410005311	signature motif; other site
228410005312	putative dimer interface [polypeptide binding]; other site
228410005313	putative phosphate binding site [ion binding]; other site
228410005314	Protein of unknown function (DUF3460); Region: DUF3460; pfam11943
228410005315	Homospermidine synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG5310
228410005316	Saccharopine dehydrogenase; Region: Saccharop_dh; pfam03435
228410005317	1 probable transmembrane helix predicted by TMHMM2.0
228410005318	Invasion gene expression up-regulator, SirB; Region: SirB; pfam04247
228410005319	4 probable transmembrane helices predicted by TMHMM2.0
228410005320	4 probable transmembrane helices predicted by TMHMM2.0
228410005321	Protein of unknown function (DUF3478); Region: DUF3478; pfam11964
228410005322	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
228410005323	8 probable transmembrane helices predicted by TMHMM2.0
228410005324	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
228410005325	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
228410005326	[2Fe-2S] cluster binding site [ion binding]; other site
228410005327	C-terminal catalytic domain of the oxygenase alpha subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C; cd00680
228410005328	alpha subunit interface [polypeptide binding]; other site
228410005329	active site
228410005330	substrate binding site [chemical binding]; other site
228410005331	Fe binding site [ion binding]; other site
228410005332	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.976) with cleavage site probability 0.755 at residue 25
228410005333	primosome assembly protein PriA; Validated; Region: PRK05580
228410005334	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410005335	ATP binding site [chemical binding]; other site
228410005336	putative Mg++ binding site [ion binding]; other site
228410005337	helicase superfamily c-terminal domain; Region: HELICc; smart00490
228410005338	ATP-binding site [chemical binding]; other site
228410005339	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
228410005340	Ligand Binding Site [chemical binding]; other site
228410005341	folate/biopterin transporter; Region: fbt; TIGR00788
228410005342	12 probable transmembrane helices predicted by TMHMM2.0
228410005343	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
228410005344	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
228410005345	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
228410005346	protein binding site [polypeptide binding]; other site
228410005347	1 probable transmembrane helix predicted by TMHMM2.0
228410005348	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
228410005349	Uncharacterized conserved protein [Function unknown]; Region: COG0327
228410005350	MltA specific insert domain; Region: MltA; smart00925
228410005351	3D domain; Region: 3D; pfam06725
228410005352	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
228410005353	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
228410005354	dimerization domain [polypeptide binding]; other site
228410005355	dimer interface [polypeptide binding]; other site
228410005356	catalytic residues [active]
228410005357	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.990 at residue 22
228410005358	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608
228410005359	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
228410005360	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.919) with cleavage site probability 0.627 at residue 20
228410005361	1 probable transmembrane helix predicted by TMHMM2.0
228410005362	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
228410005363	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
228410005364	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
228410005365	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
228410005366	Ankyrin repeat; Region: Ank; pfam00023
228410005367	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
228410005368	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
228410005369	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.985 at residue 30
228410005370	1 probable transmembrane helix predicted by TMHMM2.0
228410005371	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
228410005372	active site
228410005373	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
228410005374	active site
228410005375	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410005376	FeS/SAM binding site; other site
228410005377	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410005378	non-specific DNA binding site [nucleotide binding]; other site
228410005379	salt bridge; other site
228410005380	sequence-specific DNA binding site [nucleotide binding]; other site
228410005381	The 5' end of the gene has been destroyed by another transposon formed by genes 2700-1;Site-specific recombinase
228410005382	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410005383	ISNE
228410005384	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410005385	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410005386	ISNE1
228410005387	Winged helix-turn helix; Region: HTH_29; pfam13551
228410005388	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410005389	Homeodomain-like domain; Region: HTH_32; pfam13565
228410005390	Integrase core domain; Region: rve; pfam00665
228410005391	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410005392	Integrase core domain; Region: rve_3; pfam13683
228410005393	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
228410005394	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
228410005395	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
228410005396	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.453 at residue 25
228410005397	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
228410005398	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
228410005399	dimer interface [polypeptide binding]; other site
228410005400	active site
228410005401	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
228410005402	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
228410005403	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
228410005404	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
228410005405	substrate binding site [chemical binding]; other site
228410005406	oxyanion hole (OAH) forming residues; other site
228410005407	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
228410005408	trimer interface [polypeptide binding]; other site
228410005409	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.897 at residue 30
228410005410	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
228410005411	catalytic residues [active]
228410005412	1 probable transmembrane helix predicted by TMHMM2.0
228410005413	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 at residue 20
228410005414	BNR repeat-like domain; Region: BNR_2; pfam13088
228410005415	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.781 at residue 26
228410005416	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
228410005417	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410005418	N-terminal plug; other site
228410005419	ligand-binding site [chemical binding]; other site
228410005420	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.972) with cleavage site probability 0.939 at residue 44
228410005421	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
228410005422	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410005423	N-terminal plug; other site
228410005424	ligand-binding site [chemical binding]; other site
228410005425	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.990 at residue 43
228410005426	1 probable transmembrane helix predicted by TMHMM2.0
228410005427	M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658
228410005428	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
228410005429	active site
228410005430	metal binding site [ion binding]; metal-binding site
228410005431	Protein of unknown function DUF86; Region: DUF86; cl01031
228410005432	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
228410005433	active site
228410005434	NTP binding site [chemical binding]; other site
228410005435	metal binding triad [ion binding]; metal-binding site
228410005436	antibiotic binding site [chemical binding]; other site
228410005437	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
228410005438	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410005439	N-terminal plug; other site
228410005440	ligand-binding site [chemical binding]; other site
228410005441	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 20
228410005442	BNR repeat-like domain; Region: BNR_2; pfam13088
228410005443	1 probable transmembrane helix predicted by TMHMM2.0
228410005444	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.946 at residue 26
228410005445	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
228410005446	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
228410005447	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
228410005448	putative active site [active]
228410005449	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 29
228410005450	1 probable transmembrane helix predicted by TMHMM2.0
228410005451	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
228410005452	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410005453	N-terminal plug; other site
228410005454	ligand-binding site [chemical binding]; other site
228410005455	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 32
228410005456	Hemin uptake protein hemP; Region: hemP; pfam10636
228410005457	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
228410005458	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
228410005459	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
228410005460	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.704 at residue 33
228410005461	1 probable transmembrane helix predicted by TMHMM2.0
228410005462	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
228410005463	LysR family transcriptional regulator; Provisional; Region: PRK14997
228410005464	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
228410005465	putative effector binding pocket; other site
228410005466	dimerization interface [polypeptide binding]; other site
228410005467	Pirin-related protein [General function prediction only]; Region: COG1741
228410005468	Pirin; Region: Pirin; pfam02678
228410005469	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
228410005470	Predicted membrane protein [Function unknown]; Region: COG2259
228410005471	4 probable transmembrane helices predicted by TMHMM2.0
228410005472	1 probable transmembrane helix predicted by TMHMM2.0
228410005473	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.986 at residue 21
228410005474	1 probable transmembrane helix predicted by TMHMM2.0
228410005475	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
228410005476	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
228410005477	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
228410005478	active site
228410005479	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
228410005480	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
228410005481	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
228410005482	acyl-activating enzyme (AAE) consensus motif; other site
228410005483	putative AMP binding site [chemical binding]; other site
228410005484	putative active site [active]
228410005485	putative CoA binding site [chemical binding]; other site
228410005486	2 probable transmembrane helices predicted by TMHMM2.0
228410005487	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410005488	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410005489	ISNE
228410005490	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410005491	dead gene, 5' end removed by IS element, 3' end missing;possible probable oxidoreductase
228410005492	3 probable transmembrane helices predicted by TMHMM2.0
228410005493	Transposase; Region: HTH_Tnp_IS630; pfam01710
228410005494	DDE superfamily endonuclease; Region: DDE_3; pfam13358
228410005495	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
228410005496	PhosphatidylEthanolamine-Binding Protein (PEBP) domain; Region: PEBP; cl00227
228410005497	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
228410005498	putative active site [active]
228410005499	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.877 at residue 18
228410005500	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
228410005501	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
228410005502	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
228410005503	Ligand Binding Site [chemical binding]; other site
228410005504	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
228410005505	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
228410005506	PLD-like domain; Region: PLDc_2; pfam13091
228410005507	putative active site [active]
228410005508	catalytic site [active]
228410005509	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
228410005510	PLD-like domain; Region: PLDc_2; pfam13091
228410005511	putative active site [active]
228410005512	catalytic site [active]
228410005513	flagellin modification protein A; Provisional; Region: PRK09186
228410005514	classical (c) SDR, subgroup 8; Region: SDR_c8; cd08930
228410005515	putative NAD(P) binding site [chemical binding]; other site
228410005516	active site
228410005517	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.742) with cleavage site probability 0.413 at residue 34
228410005518	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
228410005519	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
228410005520	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
228410005521	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
228410005522	ligand binding site; other site
228410005523	tetramer interface; other site
228410005524	FOG: CBS domain [General function prediction only]; Region: COG0517
228410005525	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain associated with the NTP (Nucleotidyl transferase) domain downstream. CBS is a small domain originally identified in cystathionine beta-synthase and subsequently...; Region: CBS_pair_NTP_transferase_assoc; cd04607
228410005526	Sialic acid synthase [Cell envelope biogenesis, outer membrane]; Region: SpsE; COG2089
228410005527	NeuB family; Region: NeuB; pfam03102
228410005528	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
228410005529	NeuB binding interface [polypeptide binding]; other site
228410005530	putative substrate binding site [chemical binding]; other site
228410005531	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
228410005532	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
228410005533	putative SAM binding site [chemical binding]; other site
228410005534	homodimer interface [polypeptide binding]; other site
228410005535	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
228410005536	Peptidase S8 family domain, uncharacterized subfamily 15; Region: Peptidases_S8_15; cd07498
228410005537	active site
228410005538	catalytic triad [active]
228410005539	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
228410005540	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.880) with cleavage site probability 0.714 at residue 46
228410005541	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.991 at residue 27
228410005542	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
228410005543	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
228410005544	PemK-like protein; Region: PemK; pfam02452
228410005545	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864
228410005546	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410005547	oligomeric interface; other site
228410005548	putative active site [active]
228410005549	homodimer interface [polypeptide binding]; other site
228410005550	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
228410005551	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
228410005552	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
228410005553	ISNE4
228410005554	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410005555	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410005556	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410005557	Predicted transcription regulator containing HTH domain [Transcription]; Region: COG5499
228410005558	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; pfam09907
228410005559	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
228410005560	putative active site [active]
228410005561	homotetrameric interface [polypeptide binding]; other site
228410005562	metal binding site [ion binding]; metal-binding site
228410005563	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
228410005564	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
228410005565	putative addiction module component, TIGR02574 family; Region: stabl_TIGR02574
228410005566	flagellin; Provisional; Region: PRK12802
228410005567	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
228410005568	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
228410005569	FlaG protein; Region: FlaG; pfam03646
228410005570	flagellar capping protein; Reviewed; Region: fliD; PRK08032
228410005571	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
228410005572	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
228410005573	flagellar protein FliS; Validated; Region: fliS; PRK05685
228410005574	Flagellar protein FliT; Region: FliT; cl05125
228410005575	Flagellar protein FliT; Region: FliT; pfam05400
228410005576	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
228410005577	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
228410005578	binding surface
228410005579	TPR motif; other site
228410005580	Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilF; COG3063
228410005581	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005582	TPR motif; other site
228410005583	binding surface
228410005584	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005585	binding surface
228410005586	TPR motif; other site
228410005587	TPR repeat; Region: TPR_11; pfam13414
228410005588	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410005589	binding surface
228410005590	TPR motif; other site
228410005591	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.839 at residue 39
228410005592	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
228410005593	1 probable transmembrane helix predicted by TMHMM2.0
228410005594	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.672) with cleavage site probability 0.274 at residue 32
228410005595	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
228410005596	1 probable transmembrane helix predicted by TMHMM2.0
228410005597	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
228410005598	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
228410005599	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
228410005600	1 probable transmembrane helix predicted by TMHMM2.0
228410005601	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
228410005602	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410005603	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
228410005604	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
228410005605	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
228410005606	dockerin binding interface; other site
228410005607	1 probable transmembrane helix predicted by TMHMM2.0
228410005608	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.524 at residue 22
228410005609	1 probable transmembrane helix predicted by TMHMM2.0
228410005610	1 probable transmembrane helix predicted by TMHMM2.0
228410005611	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
228410005612	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.835) with cleavage site probability 0.692 at residue 44
228410005613	1 probable transmembrane helix predicted by TMHMM2.0
228410005614	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
228410005615	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
228410005616	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
228410005617	Walker A motif; other site
228410005618	ATP binding site [chemical binding]; other site
228410005619	Walker B motif; other site
228410005620	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
228410005621	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
228410005622	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
228410005623	3 probable transmembrane helices predicted by TMHMM2.0
228410005624	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
228410005625	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
228410005626	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
228410005627	1 probable transmembrane helix predicted by TMHMM2.0
228410005628	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
228410005629	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
228410005630	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
228410005631	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410005632	thiol reductant ABC exporter, CydD subunit; Region: CydD; TIGR02857
228410005633	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410005634	Walker A/P-loop; other site
228410005635	ATP binding site [chemical binding]; other site
228410005636	Q-loop/lid; other site
228410005637	ABC transporter signature motif; other site
228410005638	Walker B; other site
228410005639	D-loop; other site
228410005640	H-loop/switch region; other site
228410005641	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.920 at residue 31
228410005642	5 probable transmembrane helices predicted by TMHMM2.0
228410005643	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
228410005644	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
228410005645	active site
228410005646	NTP binding site [chemical binding]; other site
228410005647	metal binding triad [ion binding]; metal-binding site
228410005648	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
228410005649	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
228410005650	Zn2+ binding site [ion binding]; other site
228410005651	Mg2+ binding site [ion binding]; other site
228410005652	lytic murein transglycosylase; Provisional; Region: PRK11619
228410005653	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
228410005654	N-acetyl-D-glucosamine binding site [chemical binding]; other site
228410005655	catalytic residue [active]
228410005656	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.810 at residue 20
228410005657	glutamate dehydrogenase; Provisional; Region: PRK09414
228410005658	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
228410005659	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
228410005660	NAD(P) binding site [chemical binding]; other site
228410005661	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410005662	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410005663	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
228410005664	NE1618(fecR) and NE1619 are 2 parts of a pseudogene caused by a premature stop codon
228410005665	pseudogene, contains a premature stop codon, the other half of the gene is NE1619;possible FecR protein
228410005666	1 probable transmembrane helix predicted by TMHMM2.0
228410005667	pseudogene, contains a premature stop codon, the other half of the gene is NE1618; transmembrane sensor
228410005668	NE1620 and NE1621 are 2 parts of a pseudogene caused by a frameshift
228410005669	NE1620 and NE1621 are 2 parts of a dead gene due to a frameshift;possible tonB-dependent receptor protein
228410005670	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.859 at residue 49
228410005671	NE1620 and NE1621 are 2 parts of a dead gene due to a frameshift;TonB-dependent receptor protein
228410005672	PIN domain; Region: PIN_3; cl17397
228410005673	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
228410005674	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
228410005675	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
228410005676	substrate binding pocket [chemical binding]; other site
228410005677	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
228410005678	B12 binding site [chemical binding]; other site
228410005679	cobalt ligand [ion binding]; other site
228410005680	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
228410005681	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
228410005682	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
228410005683	HIGH motif; other site
228410005684	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
228410005685	active site
228410005686	KMSKS motif; other site
228410005687	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
228410005688	RNB domain; Region: RNB; pfam00773
228410005689	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
228410005690	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
228410005691	1 probable transmembrane helix predicted by TMHMM2.0
228410005692	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
228410005693	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
228410005694	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
228410005695	shikimate binding site; other site
228410005696	NAD(P) binding site [chemical binding]; other site
228410005697	Transglycosylase; Region: Transgly; cl17702
228410005698	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
228410005699	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.869) with cleavage site probability 0.389 at residue 58
228410005700	1 probable transmembrane helix predicted by TMHMM2.0
228410005701	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.904) with cleavage site probability 0.882 at residue 35
228410005702	1 probable transmembrane helix predicted by TMHMM2.0
228410005703	ISNE5
228410005704	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410005705	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410005706	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410005707	remnant of gene interrupted by an IS element;probable phosphate transporter
228410005708	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
228410005709	MgtE intracellular N domain; Region: MgtE_N; smart00924
228410005710	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
228410005711	Divalent cation transporter; Region: MgtE; cl00786
228410005712	5 probable transmembrane helices predicted by TMHMM2.0
228410005713	HprK-related kinase A; Region: HprK_rel_A; TIGR04352
228410005714	PqqD family protein, HPr-rel-A system; Region: PqqD_rel_X; TIGR04353
228410005715	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
228410005716	12 probable transmembrane helices predicted by TMHMM2.0
228410005717	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.898) with cleavage site probability 0.338 at residue 25
228410005718	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
228410005719	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
228410005720	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410005721	1 probable transmembrane helix predicted by TMHMM2.0
228410005722	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
228410005723	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.989) with cleavage site probability 0.489 at residue 34
228410005724	1 probable transmembrane helix predicted by TMHMM2.0
228410005725	Maf-like protein; Region: Maf; pfam02545
228410005726	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
228410005727	active site
228410005728	dimer interface [polypeptide binding]; other site
228410005729	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
228410005730	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
228410005731	putative phosphate acyltransferase; Provisional; Region: PRK05331
228410005732	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
228410005733	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
228410005734	dimer interface [polypeptide binding]; other site
228410005735	active site
228410005736	CoA binding pocket [chemical binding]; other site
228410005737	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
228410005738	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
228410005739	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
228410005740	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
228410005741	NAD(P) binding site [chemical binding]; other site
228410005742	homotetramer interface [polypeptide binding]; other site
228410005743	homodimer interface [polypeptide binding]; other site
228410005744	active site
228410005745	acyl carrier protein; Provisional; Region: acpP; PRK00982
228410005746	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
228410005747	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
228410005748	dimer interface [polypeptide binding]; other site
228410005749	active site
228410005750	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.922) with cleavage site probability 0.434 at residue 25
228410005751	YceG-like family; Region: YceG; pfam02618
228410005752	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
228410005753	dimerization interface [polypeptide binding]; other site
228410005754	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.679 at residue 34
228410005755	1 probable transmembrane helix predicted by TMHMM2.0
228410005756	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
228410005757	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
228410005758	Ligand binding site; other site
228410005759	Putative Catalytic site; other site
228410005760	DXD motif; other site
228410005761	Predicted membrane protein [Function unknown]; Region: COG2246
228410005762	GtrA-like protein; Region: GtrA; pfam04138
228410005763	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
228410005764	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
228410005765	14 probable transmembrane helices predicted by TMHMM2.0
228410005766	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
228410005767	7 probable transmembrane helices predicted by TMHMM2.0
228410005768	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.876 at residue 32
228410005769	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
228410005770	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
228410005771	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
228410005772	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
228410005773	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
228410005774	catalytic residue [active]
228410005775	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
228410005776	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
228410005777	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
228410005778	NAD(P) binding site [chemical binding]; other site
228410005779	active site
228410005780	acyl-CoA synthetase; Validated; Region: PRK09192
228410005781	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
228410005782	acyl-activating enzyme (AAE) consensus motif; other site
228410005783	active site
228410005784	L,D-transpeptidase; Provisional; Region: PRK10190
228410005785	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
228410005786	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.521 at residue 27
228410005787	1 probable transmembrane helix predicted by TMHMM2.0
228410005788	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
228410005789	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
228410005790	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
228410005791	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
228410005792	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
228410005793	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
228410005794	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
228410005795	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
228410005796	ATP-grasp domain; Region: ATP-grasp_4; cl17255
228410005797	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
228410005798	IMP binding site; other site
228410005799	dimer interface [polypeptide binding]; other site
228410005800	partial ornithine binding site; other site
228410005801	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
228410005802	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
228410005803	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
228410005804	catalytic site [active]
228410005805	subunit interface [polypeptide binding]; other site
228410005806	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
228410005807	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
228410005808	active site
228410005809	Zn binding site [ion binding]; other site
228410005810	dihydroorotase; Provisional; Region: PRK07627
228410005811	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
228410005812	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
228410005813	active site
228410005814	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
228410005815	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
228410005816	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
228410005817	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
228410005818	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
228410005819	active site
228410005820	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
228410005821	hypothetical protein; Validated; Region: PRK00228
228410005822	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
228410005823	diiron binding motif [ion binding]; other site
228410005824	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
228410005825	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
228410005826	Cysteine-rich domain; Region: CCG; pfam02754
228410005827	Cysteine-rich domain; Region: CCG; pfam02754
228410005828	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
228410005829	16S rRNA processing protein RimM; Region: 16S_RimM; TIGR02273
228410005830	RimM N-terminal domain; Region: RimM; pfam01782
228410005831	PRC-barrel domain; Region: PRC; pfam05239
228410005832	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
228410005833	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
228410005834	ISNE1
228410005835	Winged helix-turn helix; Region: HTH_29; pfam13551
228410005836	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410005837	Homeodomain-like domain; Region: HTH_32; pfam13565
228410005838	Integrase core domain; Region: rve; pfam00665
228410005839	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410005840	Integrase core domain; Region: rve_3; pfam13683
228410005841	NE1676 and NE1677 are 2 parts of a pseudogene caused by a frameshift
228410005842	NE1676 and NE1677 are 2 parts of a dead gene due to a frameshift;Glycosyl transferase, family 2
228410005843	NE1676 and NE1677 are 2 parts of a dead gene due to a frameshift;Predicted glycosyltransferases
228410005844	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.958) with cleavage site probability 0.754 at residue 26
228410005845	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
228410005846	ArsC family; Region: ArsC; pfam03960
228410005847	catalytic residues [active]
228410005848	Invasion associated locus B (IalB) protein; Region: IalB; cl02207
228410005849	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 at residue 25
228410005850	Domain of unknown function (DUF2024); Region: DUF2024; pfam09630
228410005851	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
228410005852	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410005853	S-adenosylmethionine binding site [chemical binding]; other site
228410005854	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
228410005855	O-Antigen ligase; Region: Wzy_C; pfam04932
228410005856	8 probable transmembrane helices predicted by TMHMM2.0
228410005857	Methyltransferase FkbM domain; Region: Methyltransf_21; cl17387
228410005858	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
228410005859	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
228410005860	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
228410005861	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
228410005862	Ligand binding site; other site
228410005863	oligomer interface; other site
228410005864	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
228410005865	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_2; cd12172
228410005866	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
228410005867	putative ligand binding site [chemical binding]; other site
228410005868	putative NAD binding site [chemical binding]; other site
228410005869	catalytic site [active]
228410005870	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
228410005871	extended (e) SDRs; Region: SDR_e; cd08946
228410005872	NAD(P) binding site [chemical binding]; other site
228410005873	active site
228410005874	substrate binding site [chemical binding]; other site
228410005875	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
228410005876	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410005877	motif II; other site
228410005878	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
228410005879	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
228410005880	putative active site [active]
228410005881	Protein of unknown function, DUF486; Region: DUF486; pfam04342
228410005882	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.646) with cleavage site probability 0.530 at residue 27
228410005883	4 probable transmembrane helices predicted by TMHMM2.0
228410005884	Domain of unknown function (DUF4126); Region: DUF4126; pfam13548
228410005885	3 probable transmembrane helices predicted by TMHMM2.0
228410005886	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.987) with cleavage site probability 0.952 at residue 21
228410005887	Glucokinase; Region: Glucokinase; pfam02685
228410005888	glucokinase, proteobacterial type; Region: glk; TIGR00749
228410005889	serine O-acetyltransferase; Region: cysE; TIGR01172
228410005890	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
228410005891	trimer interface [polypeptide binding]; other site
228410005892	active site
228410005893	substrate binding site [chemical binding]; other site
228410005894	CoA binding site [chemical binding]; other site
228410005895	NnrS protein; Region: NnrS; pfam05940
228410005896	12 probable transmembrane helices predicted by TMHMM2.0
228410005897	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
228410005898	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
228410005899	homodimer interface [polypeptide binding]; other site
228410005900	substrate-cofactor binding pocket; other site
228410005901	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410005902	catalytic residue [active]
228410005903	ISNE7
228410005904	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
228410005905	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; cl01481
228410005906	Pectinacetylesterase; Region: PAE; pfam03283
228410005907	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.942 at residue 24
228410005908	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
228410005909	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410005910	active site
228410005911	phosphorylation site [posttranslational modification]
228410005912	intermolecular recognition site; other site
228410005913	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410005914	Response regulator receiver domain; Region: Response_reg; pfam00072
228410005915	active site
228410005916	phosphorylation site [posttranslational modification]
228410005917	intermolecular recognition site; other site
228410005918	PAS fold; Region: PAS_3; pfam08447
228410005919	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
228410005920	putative active site [active]
228410005921	heme pocket [chemical binding]; other site
228410005922	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
228410005923	GAF domain; Region: GAF; pfam01590
228410005924	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
228410005925	PAS domain; Region: PAS_9; pfam13426
228410005926	putative active site [active]
228410005927	heme pocket [chemical binding]; other site
228410005928	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
228410005929	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
228410005930	metal binding site [ion binding]; metal-binding site
228410005931	active site
228410005932	I-site; other site
228410005933	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410005934	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
228410005935	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
228410005936	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
228410005937	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
228410005938	SelR domain; Region: SelR; pfam01641
228410005939	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.946 at residue 20
228410005940	putative lipoprotein/autotransporter domain-containing protein; Provisional; Region: PRK14849
228410005941	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.894 at residue 28
228410005942	Uncharacterized ACR, COG1993; Region: DUF190; cl00872
228410005943	chromosome condensation membrane protein; Provisional; Region: PRK14196
228410005944	4 probable transmembrane helices predicted by TMHMM2.0
228410005945	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
228410005946	MutS domain I; Region: MutS_I; pfam01624
228410005947	MutS domain II; Region: MutS_II; pfam05188
228410005948	MutS domain III; Region: MutS_III; pfam05192
228410005949	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
228410005950	Walker A/P-loop; other site
228410005951	ATP binding site [chemical binding]; other site
228410005952	Q-loop/lid; other site
228410005953	ABC transporter signature motif; other site
228410005954	Walker B; other site
228410005955	D-loop; other site
228410005956	H-loop/switch region; other site
228410005957	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
228410005958	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
228410005959	RNA/DNA hybrid binding site [nucleotide binding]; other site
228410005960	active site
228410005961	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
228410005962	periplasmic chaperone; Provisional; Region: PRK10780
228410005963	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
228410005964	1 probable transmembrane helix predicted by TMHMM2.0
228410005965	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
228410005966	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
228410005967	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
228410005968	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
228410005969	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
228410005970	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
228410005971	Surface antigen; Region: Bac_surface_Ag; pfam01103
228410005972	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 at residue 20
228410005973	zinc metallopeptidase RseP; Provisional; Region: PRK10779
228410005974	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
228410005975	active site
228410005976	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
228410005977	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
228410005978	protein binding site [polypeptide binding]; other site
228410005979	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
228410005980	putative substrate binding region [chemical binding]; other site
228410005981	4 probable transmembrane helices predicted by TMHMM2.0
228410005982	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
228410005983	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
228410005984	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
228410005985	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
228410005986	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
228410005987	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
228410005988	8 probable transmembrane helices predicted by TMHMM2.0
228410005989	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.580 at residue 40
228410005990	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
228410005991	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
228410005992	catalytic residue [active]
228410005993	putative FPP diphosphate  binding site; other site
228410005994	putative FPP binding hydrophobic cleft; other site
228410005995	dimer interface [polypeptide binding]; other site
228410005996	putative IPP diphosphate binding site; other site
228410005997	ribosome recycling factor; Reviewed; Region: frr; PRK00083
228410005998	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
228410005999	hinge region; other site
228410006000	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
228410006001	putative nucleotide binding site [chemical binding]; other site
228410006002	uridine monophosphate binding site [chemical binding]; other site
228410006003	homohexameric interface [polypeptide binding]; other site
228410006004	elongation factor Ts; Provisional; Region: tsf; PRK09377
228410006005	UBA/TS-N domain; Region: UBA; pfam00627
228410006006	Elongation factor TS; Region: EF_TS; pfam00889
228410006007	Elongation factor TS; Region: EF_TS; pfam00889
228410006008	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
228410006009	rRNA interaction site [nucleotide binding]; other site
228410006010	S8 interaction site; other site
228410006011	putative laminin-1 binding site; other site
228410006012	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
228410006013	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
228410006014	ligand binding site [chemical binding]; other site
228410006015	flexible hinge region; other site
228410006016	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
228410006017	putative switch regulator; other site
228410006018	non-specific DNA interactions [nucleotide binding]; other site
228410006019	DNA binding site [nucleotide binding]
228410006020	sequence specific DNA binding site [nucleotide binding]; other site
228410006021	putative cAMP binding site [chemical binding]; other site
228410006022	Cytochrome c; Region: Cytochrom_C; cl11414
228410006023	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
228410006024	1 probable transmembrane helix predicted by TMHMM2.0
228410006025	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
228410006026	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
228410006027	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.977) with cleavage site probability 0.776 at residue 23
228410006028	Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]; Region: Fur; COG0735
228410006029	metal binding site 2 [ion binding]; metal-binding site
228410006030	putative DNA binding helix; other site
228410006031	metal binding site 1 [ion binding]; metal-binding site
228410006032	dimer interface [polypeptide binding]; other site
228410006033	structural Zn2+ binding site [ion binding]; other site
228410006034	NnrS protein; Region: NnrS; pfam05940
228410006035	12 probable transmembrane helices predicted by TMHMM2.0
228410006036	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
228410006037	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
228410006038	active site
228410006039	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
228410006040	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
228410006041	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
228410006042	Peptidase family M50; Region: Peptidase_M50; pfam02163
228410006043	active site
228410006044	putative substrate binding region [chemical binding]; other site
228410006045	5 probable transmembrane helices predicted by TMHMM2.0
228410006046	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
228410006047	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
228410006048	active site
228410006049	HIGH motif; other site
228410006050	dimer interface [polypeptide binding]; other site
228410006051	KMSKS motif; other site
228410006052	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
228410006053	active site
228410006054	KMSKS motif; other site
228410006055	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
228410006056	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
228410006057	isocitrate dehydrogenase; Validated; Region: PRK07362
228410006058	isocitrate dehydrogenase; Reviewed; Region: PRK07006
228410006059	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
228410006060	DNA-binding site [nucleotide binding]; DNA binding site
228410006061	RNA-binding motif; other site
228410006062	Uncharacterized conserved protein [Function unknown]; Region: COG2127
228410006063	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
228410006064	Clp amino terminal domain; Region: Clp_N; pfam02861
228410006065	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410006066	Walker A motif; other site
228410006067	ATP binding site [chemical binding]; other site
228410006068	Walker B motif; other site
228410006069	arginine finger; other site
228410006070	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410006071	Walker A motif; other site
228410006072	ATP binding site [chemical binding]; other site
228410006073	Walker B motif; other site
228410006074	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
228410006075	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
228410006076	active site
228410006077	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
228410006078	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
228410006079	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.986) with cleavage site probability 0.266 at residue 48
228410006080	1 probable transmembrane helix predicted by TMHMM2.0
228410006081	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
228410006082	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410006083	putative PBP binding loops; other site
228410006084	ABC-ATPase subunit interface; other site
228410006085	6 probable transmembrane helices predicted by TMHMM2.0
228410006086	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
228410006087	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
228410006088	Walker A/P-loop; other site
228410006089	ATP binding site [chemical binding]; other site
228410006090	Q-loop/lid; other site
228410006091	ABC transporter signature motif; other site
228410006092	Walker B; other site
228410006093	D-loop; other site
228410006094	H-loop/switch region; other site
228410006095	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410006096	active site
228410006097	phosphorylation site [posttranslational modification]
228410006098	intermolecular recognition site; other site
228410006099	dimerization interface [polypeptide binding]; other site
228410006100	PAS domain S-box; Region: sensory_box; TIGR00229
228410006101	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
228410006102	Histidine kinase; Region: HisKA_3; pfam07730
228410006103	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410006104	ATP binding site [chemical binding]; other site
228410006105	Mg2+ binding site [ion binding]; other site
228410006106	G-X-G motif; other site
228410006107	NE1739 and NE1741 (both vsrDs) are two parts of a pseudogene caused by the interruption of an IS element
228410006108	NE1739 and NE1741 are 2 parts of a dead gene due to IS element insertion;Response regulator receiver domain
228410006109	ISNE6
228410006110	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
228410006111	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410006112	NE1739 and NE1741 are 2 parts of a dead gene due to IS element insertion;Bacterial regulatory protein, LuxR family
228410006113	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
228410006114	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410006115	ATP binding site [chemical binding]; other site
228410006116	Mg2+ binding site [ion binding]; other site
228410006117	G-X-G motif; other site
228410006118	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
228410006119	ATP binding site [chemical binding]; other site
228410006120	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
228410006121	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
228410006122	tetramer (dimer of dimers) interface [polypeptide binding]; other site
228410006123	active site
228410006124	dimer interface [polypeptide binding]; other site
228410006125	transcriptional regulator PhoU; Provisional; Region: PRK11115
228410006126	PhoU domain; Region: PhoU; pfam01895
228410006127	PhoU domain; Region: PhoU; pfam01895
228410006128	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
228410006129	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
228410006130	Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968
228410006131	1 probable transmembrane helix predicted by TMHMM2.0
228410006132	Tfp pilus assembly protein, tip-associated adhesin PilY1 [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilY1; COG3419
228410006133	Neisseria PilC beta-propeller domain; Region: Neisseria_PilC; pfam05567
228410006134	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.951) with cleavage site probability 0.462 at residue 27
228410006135	TraU protein; Region: TraU; cl06067
228410006136	Tfp pilus assembly protein PilX [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilX; COG4726
228410006137	PilX N-terminal; Region: PilX_N; pfam14341
228410006138	1 probable transmembrane helix predicted by TMHMM2.0
228410006139	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
228410006140	Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilW; COG4966
228410006141	1 probable transmembrane helix predicted by TMHMM2.0
228410006142	type IV pilus modification protein PilV; Region: type_IV_pilV; TIGR02523
228410006143	1 probable transmembrane helix predicted by TMHMM2.0
228410006144	Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimT; COG4970
228410006145	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
228410006146	Type II transport protein GspH; Region: GspH; pfam12019
228410006147	1 probable transmembrane helix predicted by TMHMM2.0
228410006148	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
228410006149	dimer interface [polypeptide binding]; other site
228410006150	1 probable transmembrane helix predicted by TMHMM2.0
228410006151	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.828 at residue 26
228410006152	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
228410006153	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
228410006154	nucleotide binding pocket [chemical binding]; other site
228410006155	K-X-D-G motif; other site
228410006156	catalytic site [active]
228410006157	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
228410006158	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
228410006159	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
228410006160	Dimer interface [polypeptide binding]; other site
228410006161	BRCT sequence motif; other site
228410006162	5'-methylthioadenosine phosphorylase; Validated; Region: PRK09136
228410006163	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
228410006164	active site
228410006165	catalytic residues [active]
228410006166	metal binding site [ion binding]; metal-binding site
228410006167	Predicted membrane protein [Function unknown]; Region: COG1981
228410006168	4 probable transmembrane helices predicted by TMHMM2.0
228410006169	VanZ like family; Region: VanZ; pfam04892
228410006170	24 probable transmembrane helices predicted by TMHMM2.0
228410006171	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
228410006172	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
228410006173	5 probable transmembrane helices predicted by TMHMM2.0
228410006174	hopanoid biosynthesis associated RND transporter like protein HpnN; Region: HpnN; TIGR03480
228410006175	12 probable transmembrane helices predicted by TMHMM2.0
228410006176	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.876) with cleavage site probability 0.423 at residue 42
228410006177	ISNE1
228410006178	Winged helix-turn helix; Region: HTH_29; pfam13551
228410006179	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410006180	Homeodomain-like domain; Region: HTH_32; pfam13565
228410006181	Integrase core domain; Region: rve; pfam00665
228410006182	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410006183	Integrase core domain; Region: rve_3; pfam13683
228410006184	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410006185	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410006186	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
228410006187	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.988 at residue 26
228410006188	heat shock protein 90; Provisional; Region: PRK05218
228410006189	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410006190	ATP binding site [chemical binding]; other site
228410006191	Mg2+ binding site [ion binding]; other site
228410006192	G-X-G motif; other site
228410006193	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
228410006194	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.901 at residue 22
228410006195	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
228410006196	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
228410006197	14 probable transmembrane helices predicted by TMHMM2.0
228410006198	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
228410006199	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
228410006200	14 probable transmembrane helices predicted by TMHMM2.0
228410006201	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
228410006202	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
228410006203	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
228410006204	16 probable transmembrane helices predicted by TMHMM2.0
228410006205	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
228410006206	3 probable transmembrane helices predicted by TMHMM2.0
228410006207	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
228410006208	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
228410006209	5 probable transmembrane helices predicted by TMHMM2.0
228410006210	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
228410006211	4Fe-4S binding domain; Region: Fer4; cl02805
228410006212	4Fe-4S binding domain; Region: Fer4; pfam00037
228410006213	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
228410006214	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
228410006215	8 probable transmembrane helices predicted by TMHMM2.0
228410006216	NADH dehydrogenase subunit G; Validated; Region: PRK09129
228410006217	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
228410006218	catalytic loop [active]
228410006219	iron binding site [ion binding]; other site
228410006220	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
228410006221	MopB_NDH-1_NuoG2: The second domain of the NuoG subunit of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1), found in beta- and gammaproteobacteria. The NDH-1 is the first energy-transducting complex in the respiratory chain and functions as...; Region: MopB_NDH-1_NuoG2; cd02772
228410006222	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
228410006223	SLBB domain; Region: SLBB; pfam10531
228410006224	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
228410006225	NADH dehydrogenase subunit E; Validated; Region: PRK07539
228410006226	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
228410006227	putative dimer interface [polypeptide binding]; other site
228410006228	[2Fe-2S] cluster binding site [ion binding]; other site
228410006229	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
228410006230	NADH dehydrogenase subunit D; Validated; Region: PRK06075
228410006231	1 probable transmembrane helix predicted by TMHMM2.0
228410006232	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
228410006233	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
228410006234	NADH dehydrogenase subunit B; Validated; Region: PRK06411
228410006235	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
228410006236	3 probable transmembrane helices predicted by TMHMM2.0
228410006237	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.669) with cleavage site probability 0.266 at residue 29
228410006238	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
228410006239	2 probable transmembrane helices predicted by TMHMM2.0
228410006240	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
228410006241	triosephosphate isomerase; Provisional; Region: PRK14567
228410006242	substrate binding site [chemical binding]; other site
228410006243	dimer interface [polypeptide binding]; other site
228410006244	catalytic triad [active]
228410006245	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
228410006246	catalytic core [active]
228410006247	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
228410006248	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
228410006249	Peptidase family M23; Region: Peptidase_M23; pfam01551
228410006250	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.826) with cleavage site probability 0.810 at residue 44
228410006251	1 probable transmembrane helix predicted by TMHMM2.0
228410006252	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
228410006253	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
228410006254	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
228410006255	protein binding site [polypeptide binding]; other site
228410006256	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
228410006257	Catalytic dyad [active]
228410006258	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.851 at residue 30
228410006259	1 probable transmembrane helix predicted by TMHMM2.0
228410006260	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
228410006261	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
228410006262	ATP binding site [chemical binding]; other site
228410006263	substrate interface [chemical binding]; other site
228410006264	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
228410006265	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410006266	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410006267	Walker A/P-loop; other site
228410006268	ATP binding site [chemical binding]; other site
228410006269	Q-loop/lid; other site
228410006270	ABC transporter signature motif; other site
228410006271	Walker B; other site
228410006272	D-loop; other site
228410006273	H-loop/switch region; other site
228410006274	6 probable transmembrane helices predicted by TMHMM2.0
228410006275	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.569 at residue 40
228410006276	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
228410006277	Low molecular weight phosphatase family; Region: LMWPc; cd00115
228410006278	active site
228410006279	NE1786 and NE1787 are 2 parts of a pseudogene caused by a frameshift
228410006280	NE1786 and NE1787 are 2 parts of a dead gene due to a frameshift; GumJ protein
228410006281	2 probable transmembrane helices predicted by TMHMM2.0
228410006282	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.937) with cleavage site probability 0.662 at residue 34
228410006283	NE1786 and NE1787 are 2 parts of a dead gene due to a frameshift; GumJ protein
228410006284	1 probable transmembrane helix predicted by TMHMM2.0
228410006285	ISNE4
228410006286	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410006287	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410006288	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410006289	Sugar-transfer associated ATP-grasp; Region: ATPgrasp_ST; pfam14397
228410006290	Sugar-transfer associated ATP-grasp; Region: ATPgrasp_ST; pfam14397
228410006291	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
228410006292	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
228410006293	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u9; cd10933
228410006294	putative active site [active]
228410006295	putative catalytic site [active]
228410006296	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
228410006297	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
228410006298	active site
228410006299	dimer interface [polypeptide binding]; other site
228410006300	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
228410006301	Ligand Binding Site [chemical binding]; other site
228410006302	Molecular Tunnel; other site
228410006303	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp2; TIGR03088
228410006304	This family is most closely related to the GT1 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis; Region: GT1_WbnK_like; cd03807
228410006305	putative ADP-binding pocket [chemical binding]; other site
228410006306	exosortase A; Region: exosortase_1; TIGR03109
228410006307	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
228410006308	EpsI family protein; Region: EpsI_fam; TIGR02914
228410006309	8 probable transmembrane helices predicted by TMHMM2.0
228410006310	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
228410006311	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
228410006312	FemAB-related protein, PEP-CTERM system-associated; Region: pepcterm_femAB; TIGR03019
228410006313	Putative catalytic domain of uncharacterized prokaryotic polysaccharide deacetylases similar to bacterial PuuE allantoinases and Helicobacter pylori peptidoglycan deacetylase (HpPgdA); Region: CE4_PuuE_HpPgdA_like_2; cd10941
228410006314	polysaccharide deacetylase family protein, PEP-CTERM locus subfamily; Region: pepcterm_polyde; TIGR03006
228410006315	putative active site [active]
228410006316	putative catalytic site [active]
228410006317	putative secretion ATPase, PEP-CTERM locus subfamily; Region: pepcterm_ATPase; TIGR03015
228410006318	AAA ATPase domain; Region: AAA_16; pfam13191
228410006319	uncharacterized protein, PEP-CTERM system associated; Region: pepcterm_hypo_1; TIGR03016
228410006320	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.841) with cleavage site probability 0.829 at residue 36
228410006321	exopolysaccharide/PEP-CTERM locus tyrosine autokinase; Region: pepcterm_TyrKin; TIGR03018
228410006322	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
228410006323	polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Region: pepcterm_ChnLen; TIGR03007
228410006324	Chain length determinant protein; Region: Wzz; cl15801
228410006325	3 probable transmembrane helices predicted by TMHMM2.0
228410006326	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
228410006327	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
228410006328	SLBB domain; Region: SLBB; pfam10531
228410006329	1 probable transmembrane helix predicted by TMHMM2.0
228410006330	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.922) with cleavage site probability 0.650 at residue 27
228410006331	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
228410006332	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410006333	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410006334	ABC transporter; Region: ABC_tran_2; pfam12848
228410006335	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
228410006336	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
228410006337	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
228410006338	ATP binding site [chemical binding]; other site
228410006339	Mg++ binding site [ion binding]; other site
228410006340	motif III; other site
228410006341	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410006342	nucleotide binding region [chemical binding]; other site
228410006343	ATP-binding site [chemical binding]; other site
228410006344	DNA repair protein RadA; Provisional; Region: PRK11823
228410006345	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
228410006346	Walker A motif/ATP binding site; other site
228410006347	ATP binding site [chemical binding]; other site
228410006348	Walker B motif; other site
228410006349	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
228410006350	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
228410006351	malate--CoA ligase subunit beta; Provisional; Region: PRK14046
228410006352	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
228410006353	CoA-ligase; Region: Ligase_CoA; pfam00549
228410006354	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
228410006355	CoA binding domain; Region: CoA_binding; smart00881
228410006356	CoA-ligase; Region: Ligase_CoA; pfam00549
228410006357	NE1812 and NE1813 are 2 parts of a pseudogene caused by 2 premature stop codons
228410006358	pseudogene, contains 2 premature stop codons, the other part of the gene is NE1813;Haem peroxidase superfamily:Catalase/peroxidase HPI
228410006359	pseudogene, contains 2 premature stop codons, the other part of the gene is NE1812;catalase-peroxidase
228410006360	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.985) with cleavage site probability 0.490 at residue 22
228410006361	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
228410006362	ISNE3
228410006363	putative transposase OrfB; Reviewed; Region: PHA02517
228410006364	HTH-like domain; Region: HTH_21; pfam13276
228410006365	Integrase core domain; Region: rve; pfam00665
228410006366	Integrase core domain; Region: rve_3; pfam13683
228410006367	Domain of unknown function (DUF955); Region: DUF955; pfam06114
228410006368	NE1819 and NE1820 are 2 parts of a pseudogene caused by a premature stop codons
228410006369	pseudogene, contains a premature stop codon, the other half of the gene is NE1820; membrane protein
228410006370	2 probable transmembrane helices predicted by TMHMM2.0
228410006371	pseudogene, contains a premature stop codon, the other half of the gene is NE1819; membrane protein
228410006372	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
228410006373	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
228410006374	GTP-binding protein YchF; Reviewed; Region: PRK09601
228410006375	YchF GTPase; Region: YchF; cd01900
228410006376	G1 box; other site
228410006377	GTP/Mg2+ binding site [chemical binding]; other site
228410006378	Switch I region; other site
228410006379	G2 box; other site
228410006380	Switch II region; other site
228410006381	G3 box; other site
228410006382	G4 box; other site
228410006383	G5 box; other site
228410006384	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
228410006385	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
228410006386	putative active site [active]
228410006387	catalytic residue [active]
228410006388	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
228410006389	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
228410006390	5S rRNA interface [nucleotide binding]; other site
228410006391	CTC domain interface [polypeptide binding]; other site
228410006392	L16 interface [polypeptide binding]; other site
228410006393	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
228410006394	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
228410006395	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
228410006396	active site
228410006397	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
228410006398	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
228410006399	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
228410006400	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
228410006401	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
228410006402	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.287 at residue 21
228410006403	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
228410006404	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
228410006405	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
228410006406	Switch I; other site
228410006407	Switch II; other site
228410006408	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
228410006409	septum formation inhibitor; Reviewed; Region: minC; PRK00339
228410006410	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
228410006411	Outer membrane lipoprotein Slp family; Region: Slp; pfam03843
228410006412	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.897 at residue 23
228410006413	Predicted periplasmic lipoprotein (DUF2279); Region: DUF2279; pfam10043
228410006414	1 probable transmembrane helix predicted by TMHMM2.0
228410006415	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
228410006416	TrkA-N domain; Region: TrkA_N; pfam02254
228410006417	TrkA-C domain; Region: TrkA_C; pfam02080
228410006418	TrkA-N domain; Region: TrkA_N; pfam02254
228410006419	Cation transport protein; Region: TrkH; cl17365
228410006420	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
228410006421	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.909) with cleavage site probability 0.555 at residue 34
228410006422	11 probable transmembrane helices predicted by TMHMM2.0
228410006423	Response regulator receiver domain; Region: Response_reg; pfam00072
228410006424	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410006425	active site
228410006426	phosphorylation site [posttranslational modification]
228410006427	intermolecular recognition site; other site
228410006428	dimerization interface [polypeptide binding]; other site
228410006429	Chorismate lyase; Region: Chor_lyase; cl01230
228410006430	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
228410006431	UbiA prenyltransferase family; Region: UbiA; pfam01040
228410006432	9 probable transmembrane helices predicted by TMHMM2.0
228410006433	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
228410006434	ISNE1
228410006435	Winged helix-turn helix; Region: HTH_29; pfam13551
228410006436	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410006437	Homeodomain-like domain; Region: HTH_32; pfam13565
228410006438	Integrase core domain; Region: rve; pfam00665
228410006439	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410006440	Integrase core domain; Region: rve_3; pfam13683
228410006441	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.605) with cleavage site probability 0.438 at residue 31
228410006442	NE1842 and NE1844 are two parts of a pseudogene caused by the interruption of an IS element
228410006443	NE1842 and NE1844 are 2 parts of a dead gene due to IS element insertion;conserved hypothetical protein
228410006444	5 probable transmembrane helices predicted by TMHMM2.0
228410006445	ISNE2
228410006446	Winged helix-turn helix; Region: HTH_29; pfam13551
228410006447	Integrase core domain; Region: rve; pfam00665
228410006448	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410006449	Integrase core domain; Region: rve_3; pfam13683
228410006450	NE1842 and NE1844 are 2 parts of a dead gene due to IS element insertion;conserved hypothetical protein
228410006451	3 probable transmembrane helices predicted by TMHMM2.0
228410006452	ISNE1
228410006453	Winged helix-turn helix; Region: HTH_29; pfam13551
228410006454	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410006455	Homeodomain-like domain; Region: HTH_32; pfam13565
228410006456	Integrase core domain; Region: rve; pfam00665
228410006457	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410006458	Integrase core domain; Region: rve_3; pfam13683
228410006459	HDOD domain; Region: HDOD; pfam08668
228410006460	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
228410006461	Zn2+ binding site [ion binding]; other site
228410006462	Mg2+ binding site [ion binding]; other site
228410006463	1 probable transmembrane helix predicted by TMHMM2.0
228410006464	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
228410006465	cyclase homology domain; Region: CHD; cd07302
228410006466	nucleotidyl binding site; other site
228410006467	metal binding site [ion binding]; metal-binding site
228410006468	dimer interface [polypeptide binding]; other site
228410006469	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
228410006470	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
228410006471	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
228410006472	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
228410006473	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
228410006474	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
228410006475	ssDNA binding site; other site
228410006476	generic binding surface II; other site
228410006477	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410006478	ATP binding site [chemical binding]; other site
228410006479	putative Mg++ binding site [ion binding]; other site
228410006480	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410006481	nucleotide binding region [chemical binding]; other site
228410006482	ATP-binding site [chemical binding]; other site
228410006483	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
228410006484	homotrimer interaction site [polypeptide binding]; other site
228410006485	putative active site [active]
228410006486	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
228410006487	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
228410006488	hinge; other site
228410006489	active site
228410006490	1 probable transmembrane helix predicted by TMHMM2.0
228410006491	argininosuccinate lyase; Provisional; Region: PRK00855
228410006492	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
228410006493	active sites [active]
228410006494	tetramer interface [polypeptide binding]; other site
228410006495	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.918) with cleavage site probability 0.676 at residue 19
228410006496	Phosphotransferase enzyme family; Region: APH; pfam01636
228410006497	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
228410006498	active site
228410006499	substrate binding site [chemical binding]; other site
228410006500	ATP binding site [chemical binding]; other site
228410006501	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
228410006502	Dynamin family; Region: Dynamin_N; pfam00350
228410006503	G1 box; other site
228410006504	GTP/Mg2+ binding site [chemical binding]; other site
228410006505	G2 box; other site
228410006506	Switch I region; other site
228410006507	G3 box; other site
228410006508	Switch II region; other site
228410006509	G4 box; other site
228410006510	2 probable transmembrane helices predicted by TMHMM2.0
228410006511	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
228410006512	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410006513	S-adenosylmethionine binding site [chemical binding]; other site
228410006514	HDOD domain; Region: HDOD; pfam08668
228410006515	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
228410006516	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410006517	active site
228410006518	phosphorylation site [posttranslational modification]
228410006519	intermolecular recognition site; other site
228410006520	dimerization interface [polypeptide binding]; other site
228410006521	CheB methylesterase; Region: CheB_methylest; pfam01339
228410006522	chemoreceptor glutamine deamidase CheD; Provisional; Region: PRK13487
228410006523	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
228410006524	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
228410006525	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
228410006526	PAS domain; Region: PAS_9; pfam13426
228410006527	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
228410006528	putative active site [active]
228410006529	heme pocket [chemical binding]; other site
228410006530	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
228410006531	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410006532	dimerization interface [polypeptide binding]; other site
228410006533	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
228410006534	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
228410006535	dimer interface [polypeptide binding]; other site
228410006536	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
228410006537	putative CheW interface [polypeptide binding]; other site
228410006538	3 probable transmembrane helices predicted by TMHMM2.0
228410006539	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
228410006540	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
228410006541	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
228410006542	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410006543	dimerization interface [polypeptide binding]; other site
228410006544	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
228410006545	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
228410006546	dimer interface [polypeptide binding]; other site
228410006547	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
228410006548	putative CheW interface [polypeptide binding]; other site
228410006549	3 probable transmembrane helices predicted by TMHMM2.0
228410006550	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
228410006551	chemotaxis protein CheA; Provisional; Region: PRK10547
228410006552	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
228410006553	putative binding surface; other site
228410006554	active site
228410006555	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
228410006556	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410006557	ATP binding site [chemical binding]; other site
228410006558	Mg2+ binding site [ion binding]; other site
228410006559	G-X-G motif; other site
228410006560	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
228410006561	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
228410006562	SCP-2 sterol transfer family; Region: SCP2; cl01225
228410006563	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
228410006564	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
228410006565	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
228410006566	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
228410006567	Walker A/P-loop; other site
228410006568	ATP binding site [chemical binding]; other site
228410006569	Q-loop/lid; other site
228410006570	ABC transporter signature motif; other site
228410006571	Walker B; other site
228410006572	D-loop; other site
228410006573	H-loop/switch region; other site
228410006574	TOBE domain; Region: TOBE_2; pfam08402
228410006575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410006576	dimer interface [polypeptide binding]; other site
228410006577	conserved gate region; other site
228410006578	ABC-ATPase subunit interface; other site
228410006579	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.709) with cleavage site probability 0.155 at residue 35
228410006580	6 probable transmembrane helices predicted by TMHMM2.0
228410006581	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
228410006582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410006583	dimer interface [polypeptide binding]; other site
228410006584	conserved gate region; other site
228410006585	putative PBP binding loops; other site
228410006586	ABC-ATPase subunit interface; other site
228410006587	6 probable transmembrane helices predicted by TMHMM2.0
228410006588	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
228410006589	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
228410006590	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.399 at residue 25
228410006591	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
228410006592	dimer interface [polypeptide binding]; other site
228410006593	[2Fe-2S] cluster binding site [ion binding]; other site
228410006594	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
228410006595	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
228410006596	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
228410006597	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
228410006598	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
228410006599	Tetramer interface [polypeptide binding]; other site
228410006600	active site
228410006601	FMN-binding site [chemical binding]; other site
228410006602	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
228410006603	Sel1-like repeats; Region: SEL1; smart00671
228410006604	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.987) with cleavage site probability 0.507 at residue 22
228410006605	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
228410006606	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.942) with cleavage site probability 0.154 at residue 27
228410006607	1 probable transmembrane helix predicted by TMHMM2.0
228410006608	ISNE1
228410006609	Winged helix-turn helix; Region: HTH_29; pfam13551
228410006610	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410006611	Homeodomain-like domain; Region: HTH_32; pfam13565
228410006612	Integrase core domain; Region: rve; pfam00665
228410006613	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410006614	Integrase core domain; Region: rve_3; pfam13683
228410006615	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
228410006616	Protein of unknown function (DUF3696); Region: DUF3696; pfam12476
228410006617	Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases; Region: Adenylation_DNA_ligase_like; cl12015
228410006618	active site
228410006619	Domain of unknown function (DUF202); Region: DUF202; pfam02656
228410006620	2 probable transmembrane helices predicted by TMHMM2.0
228410006621	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
228410006622	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
228410006623	tetramer interface [polypeptide binding]; other site
228410006624	heme binding pocket [chemical binding]; other site
228410006625	NADPH binding site [chemical binding]; other site
228410006626	Protein of unknown function (DUF3422); Region: DUF3422; pfam11902
228410006627	1 probable transmembrane helix predicted by TMHMM2.0
228410006628	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
228410006629	8 probable transmembrane helices predicted by TMHMM2.0
228410006630	EVE domain; Region: EVE; cl00728
228410006631	Cell division protein ZapA; Region: ZapA; pfam05164
228410006632	L-aspartate oxidase; Provisional; Region: PRK09077
228410006633	L-aspartate oxidase; Provisional; Region: PRK06175
228410006634	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
228410006635	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.861) with cleavage site probability 0.340 at residue 28
228410006636	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
228410006637	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
228410006638	homodimer interface [polypeptide binding]; other site
228410006639	substrate-cofactor binding pocket; other site
228410006640	catalytic residue [active]
228410006641	Zinc-finger domain; Region: zf-CHCC; cl01821
228410006642	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
228410006643	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
228410006644	active site
228410006645	substrate binding site [chemical binding]; other site
228410006646	metal binding site [ion binding]; metal-binding site
228410006647	NAD synthetase; Provisional; Region: PRK13981
228410006648	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
228410006649	multimer interface [polypeptide binding]; other site
228410006650	active site
228410006651	catalytic triad [active]
228410006652	protein interface 1 [polypeptide binding]; other site
228410006653	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
228410006654	homodimer interface [polypeptide binding]; other site
228410006655	NAD binding pocket [chemical binding]; other site
228410006656	ATP binding pocket [chemical binding]; other site
228410006657	Mg binding site [ion binding]; other site
228410006658	active-site loop [active]
228410006659	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
228410006660	Peptidase family M48; Region: Peptidase_M48; pfam01435
228410006661	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.743) with cleavage site probability 0.724 at residue 34
228410006662	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410006663	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410006664	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410006665	1 probable transmembrane helix predicted by TMHMM2.0
228410006666	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
228410006667	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
228410006668	Walker A/P-loop; other site
228410006669	ATP binding site [chemical binding]; other site
228410006670	Q-loop/lid; other site
228410006671	ABC transporter signature motif; other site
228410006672	Walker B; other site
228410006673	D-loop; other site
228410006674	H-loop/switch region; other site
228410006675	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410006676	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
228410006677	FtsX-like permease family; Region: FtsX; pfam02687
228410006678	4 probable transmembrane helices predicted by TMHMM2.0
228410006679	putative monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12648
228410006680	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
228410006681	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
228410006682	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
228410006683	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
228410006684	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
228410006685	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.892 at residue 22
228410006686	23 probable transmembrane helices predicted by TMHMM2.0
228410006687	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK09094
228410006688	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.703) with cleavage site probability 0.435 at residue 20
228410006689	3 probable transmembrane helices predicted by TMHMM2.0
228410006690	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK12666
228410006691	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
228410006692	14 probable transmembrane helices predicted by TMHMM2.0
228410006693	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK08965
228410006694	4 probable transmembrane helices predicted by TMHMM2.0
228410006695	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK06161
228410006696	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.293 at residue 35
228410006697	3 probable transmembrane helices predicted by TMHMM2.0
228410006698	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12671
228410006699	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.659) with cleavage site probability 0.235 at residue 27
228410006700	3 probable transmembrane helices predicted by TMHMM2.0
228410006701	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.388 at residue 23
228410006702	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
228410006703	GST_N family, Saccharomyces cerevisiae GTT2-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT2. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing...; Region: GST_N_GTT2_like; cd03051
228410006704	putative C-terminal domain interface [polypeptide binding]; other site
228410006705	putative GSH binding site (G-site) [chemical binding]; other site
228410006706	putative dimer interface [polypeptide binding]; other site
228410006707	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
228410006708	N-terminal domain interface [polypeptide binding]; other site
228410006709	dimer interface [polypeptide binding]; other site
228410006710	substrate binding pocket (H-site) [chemical binding]; other site
228410006711	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410006712	dimerization interface [polypeptide binding]; other site
228410006713	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
228410006714	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
228410006715	metal binding site [ion binding]; metal-binding site
228410006716	active site
228410006717	I-site; other site
228410006718	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410006719	2 probable transmembrane helices predicted by TMHMM2.0
228410006720	Predicted membrane protein [Function unknown]; Region: COG1238
228410006721	4 probable transmembrane helices predicted by TMHMM2.0
228410006722	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
228410006723	putative GSH binding site [chemical binding]; other site
228410006724	catalytic residues [active]
228410006725	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
228410006726	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410006727	S-adenosylmethionine binding site [chemical binding]; other site
228410006728	peptide chain release factor 1; Validated; Region: prfA; PRK00591
228410006729	This domain is found in peptide chain release factors; Region: PCRF; smart00937
228410006730	RF-1 domain; Region: RF-1; pfam00472
228410006731	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
228410006732	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
228410006733	tRNA; other site
228410006734	putative tRNA binding site [nucleotide binding]; other site
228410006735	putative NADP binding site [chemical binding]; other site
228410006736	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
228410006737	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
228410006738	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
228410006739	substrate binding pocket [chemical binding]; other site
228410006740	chain length determination region; other site
228410006741	substrate-Mg2+ binding site; other site
228410006742	catalytic residues [active]
228410006743	aspartate-rich region 1; other site
228410006744	active site lid residues [active]
228410006745	aspartate-rich region 2; other site
228410006746	norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role  in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454
228410006747	metal ion-dependent adhesion site (MIDAS); other site
228410006748	MoxR-like ATPases [General function prediction only]; Region: COG0714
228410006749	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
228410006750	CbbQ/NirQ/NorQ C-terminal; Region: CbbQ_C; pfam08406
228410006751	Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of photorespiration. Rubisco...; Region: RuBisCO_small; cd03527
228410006752	multimerization interface [polypeptide binding]; other site
228410006753	ribulose bisophosphate carboxylase; Reviewed; Region: rbcL; PRK04208
228410006754	Ribulose bisphosphate carboxylase large chain; Region: RuBisCO_large; cl08232
228410006755	dimer interface [polypeptide binding]; other site
228410006756	catalytic residue [active]
228410006757	metal binding site [ion binding]; metal-binding site
228410006758	Transcriptional regulator [Transcription]; Region: LysR; COG0583
228410006759	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
228410006760	The C-terminal substrate binding of LysR-type transcriptional regulator (CbbR) of RubisCO operon, which is involved in the carbon dioxide fixation, contains the type 2 periplasmic binding fold; Region: PBP2_CbbR_RubisCO_like; cd08419
228410006761	putative dimerization interface [polypeptide binding]; other site
228410006762	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
228410006763	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410006764	active site
228410006765	phosphorylation site [posttranslational modification]
228410006766	intermolecular recognition site; other site
228410006767	dimerization interface [polypeptide binding]; other site
228410006768	Chemotaxis phosphatase, CheZ; Region: CheZ; pfam04344
228410006769	ISNE1
228410006770	Winged helix-turn helix; Region: HTH_29; pfam13551
228410006771	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410006772	Homeodomain-like domain; Region: HTH_32; pfam13565
228410006773	Integrase core domain; Region: rve; pfam00665
228410006774	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410006775	Integrase core domain; Region: rve_3; pfam13683
228410006776	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
228410006777	active site clefts [active]
228410006778	zinc binding site [ion binding]; other site
228410006779	dimer interface [polypeptide binding]; other site
228410006780	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
228410006781	Sulfate transporter family; Region: Sulfate_transp; pfam00916
228410006782	8 probable transmembrane helices predicted by TMHMM2.0
228410006783	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
228410006784	Smr domain; Region: Smr; pfam01713
228410006785	thioredoxin reductase; Provisional; Region: PRK10262
228410006786	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
228410006787	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410006788	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
228410006789	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
228410006790	motif 1; other site
228410006791	active site
228410006792	motif 2; other site
228410006793	motif 3; other site
228410006794	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; cl17802
228410006795	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
228410006796	DHHA1 domain; Region: DHHA1; pfam02272
228410006797	recombination regulator RecX; Reviewed; Region: recX; PRK00117
228410006798	recombinase A; Provisional; Region: recA; PRK09354
228410006799	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
228410006800	hexamer interface [polypeptide binding]; other site
228410006801	Walker A motif; other site
228410006802	ATP binding site [chemical binding]; other site
228410006803	Walker B motif; other site
228410006804	adenylate kinase; Reviewed; Region: adk; PRK00279
228410006805	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
228410006806	AMP-binding site [chemical binding]; other site
228410006807	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
228410006808	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.622 at residue 19
228410006809	6-phosphofructokinase; Provisional; Region: PRK14072
228410006810	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
228410006811	active site
228410006812	ADP/pyrophosphate binding site [chemical binding]; other site
228410006813	dimerization interface [polypeptide binding]; other site
228410006814	allosteric effector site; other site
228410006815	fructose-1,6-bisphosphate binding site; other site
228410006816	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
228410006817	membrane-bound proton-translocating pyrophosphatase; Validated; Region: hppA; PRK00733
228410006818	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.967) with cleavage site probability 0.760 at residue 29
228410006819	15 probable transmembrane helices predicted by TMHMM2.0
228410006820	Protein of unknown function (DUF3750); Region: DUF3750; pfam12570
228410006821	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.828) with cleavage site probability 0.186 at residue 26
228410006822	1 probable transmembrane helix predicted by TMHMM2.0
228410006823	ISNE5
228410006824	2974 and 2975 do not overlap, so there can be no frameshift during translation, so it is a dead IS element;possible transposase
228410006825	dead IS element, 2974 and 2975 do not overlap so there can be no frameshift during translation; ISCc1, transposase OrfB
228410006826	Winged helix-turn helix; Region: HTH_29; pfam13551
228410006827	Integrase core domain; Region: rve; pfam00665
228410006828	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410006829	Integrase core domain; Region: rve_3; pfam13683
228410006830	ISNE2
228410006831	defective integrase
228410006832	dead gene due to multiple premature stop codons, NE1942 is the model for the 5' end; integrase
228410006833	dead due to multiple premature stop codons, NE1941 is the 3' of the transposon; integrase
228410006834	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
228410006835	OsmC-like protein; Region: OsmC; pfam02566
228410006836	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
228410006837	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
228410006838	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
228410006839	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
228410006840	hypothetical protein; Provisional; Region: PRK11281
228410006841	Tumour-suppressor protein CtIP N-terminal domain; Region: CtIP_N; pfam10482
228410006842	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
228410006843	Transcriptional regulator PadR-like family; Region: PadR; cl17335
228410006844	Mechanosensitive ion channel; Region: MS_channel; pfam00924
228410006845	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.942 at residue 24
228410006846	11 probable transmembrane helices predicted by TMHMM2.0
228410006847	chaperone protein DnaJ; Provisional; Region: PRK10767
228410006848	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
228410006849	HSP70 interaction site [polypeptide binding]; other site
228410006850	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
228410006851	substrate binding site [polypeptide binding]; other site
228410006852	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
228410006853	Zn binding sites [ion binding]; other site
228410006854	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
228410006855	dimer interface [polypeptide binding]; other site
228410006856	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
228410006857	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
228410006858	nucleotide binding site [chemical binding]; other site
228410006859	GrpE; Region: GrpE; pfam01025
228410006860	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
228410006861	dimer interface [polypeptide binding]; other site
228410006862	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
228410006863	adenylosuccinate lyase; Provisional; Region: PRK09285
228410006864	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
228410006865	tetramer interface [polypeptide binding]; other site
228410006866	active site
228410006867	putative glutathione S-transferase; Provisional; Region: PRK10357
228410006868	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
228410006869	putative C-terminal domain interface [polypeptide binding]; other site
228410006870	putative GSH binding site (G-site) [chemical binding]; other site
228410006871	putative dimer interface [polypeptide binding]; other site
228410006872	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
228410006873	dimer interface [polypeptide binding]; other site
228410006874	N-terminal domain interface [polypeptide binding]; other site
228410006875	putative substrate binding pocket (H-site) [chemical binding]; other site
228410006876	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
228410006877	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
228410006878	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
228410006879	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
228410006880	active site
228410006881	dimerization interface [polypeptide binding]; other site
228410006882	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
228410006883	mce related protein; Region: MCE; pfam02470
228410006884	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.981) with cleavage site probability 0.928 at residue 25
228410006885	1 probable transmembrane helix predicted by TMHMM2.0
228410006886	Protein of unknown function (DUF330); Region: DUF330; cl01135
228410006887	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.469 at residue 19
228410006888	diaminopimelate decarboxylase; Region: lysA; TIGR01048
228410006889	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
228410006890	active site
228410006891	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
228410006892	substrate binding site [chemical binding]; other site
228410006893	catalytic residues [active]
228410006894	dimer interface [polypeptide binding]; other site
228410006895	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
228410006896	active site lid residues [active]
228410006897	substrate binding pocket [chemical binding]; other site
228410006898	catalytic residues [active]
228410006899	substrate-Mg2+ binding site; other site
228410006900	aspartate-rich region 1; other site
228410006901	aspartate-rich region 2; other site
228410006902	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
228410006903	active site
228410006904	dimer interface [polypeptide binding]; other site
228410006905	this is a gene remnant;conserved hypothetical protein
228410006906	2 probable transmembrane helices predicted by TMHMM2.0
228410006907	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.935) with cleavage site probability 0.265 at residue 23
228410006908	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
228410006909	IHF dimer interface [polypeptide binding]; other site
228410006910	IHF - DNA interface [nucleotide binding]; other site
228410006911	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
228410006912	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
228410006913	RNA binding site [nucleotide binding]; other site
228410006914	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
228410006915	RNA binding site [nucleotide binding]; other site
228410006916	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
228410006917	RNA binding site [nucleotide binding]; other site
228410006918	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
228410006919	RNA binding site [nucleotide binding]; other site
228410006920	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
228410006921	RNA binding site [nucleotide binding]; other site
228410006922	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
228410006923	RNA binding site [nucleotide binding]; other site
228410006924	cytidylate kinase; Provisional; Region: cmk; PRK00023
228410006925	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
228410006926	CMP-binding site; other site
228410006927	The sites determining sugar specificity; other site
228410006928	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
228410006929	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
228410006930	hinge; other site
228410006931	active site
228410006932	2 probable transmembrane helices predicted by TMHMM2.0
228410006933	DNA topoisomerase III; Validated; Region: PRK08173
228410006934	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
228410006935	active site
228410006936	putative interdomain interaction site [polypeptide binding]; other site
228410006937	putative metal-binding site [ion binding]; other site
228410006938	putative nucleotide binding site [chemical binding]; other site
228410006939	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
228410006940	domain I; other site
228410006941	DNA binding groove [nucleotide binding]
228410006942	phosphate binding site [ion binding]; other site
228410006943	domain II; other site
228410006944	domain III; other site
228410006945	nucleotide binding site [chemical binding]; other site
228410006946	catalytic site [active]
228410006947	domain IV; other site
228410006948	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
228410006949	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
228410006950	Protein of unknown function (DUF494); Region: DUF494; pfam04361
228410006951	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
228410006952	DNA protecting protein DprA; Region: dprA; TIGR00732
228410006953	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
228410006954	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.987) with cleavage site probability 0.457 at residue 23
228410006955	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
228410006956	active site
228410006957	catalytic residues [active]
228410006958	metal binding site [ion binding]; metal-binding site
228410006959	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
228410006960	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
228410006961	putative active site [active]
228410006962	substrate binding site [chemical binding]; other site
228410006963	putative cosubstrate binding site; other site
228410006964	catalytic site [active]
228410006965	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
228410006966	substrate binding site [chemical binding]; other site
228410006967	16S rRNA methyltransferase B; Provisional; Region: PRK10901
228410006968	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
228410006969	putative RNA binding site [nucleotide binding]; other site
228410006970	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410006971	S-adenosylmethionine binding site [chemical binding]; other site
228410006972	Domain of unknown function (DUF4390); Region: DUF4390; pfam14334
228410006973	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
228410006974	dimerization interface [polypeptide binding]; other site
228410006975	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
228410006976	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410006977	dimer interface [polypeptide binding]; other site
228410006978	phosphorylation site [posttranslational modification]
228410006979	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410006980	ATP binding site [chemical binding]; other site
228410006981	Mg2+ binding site [ion binding]; other site
228410006982	G-X-G motif; other site
228410006983	3 probable transmembrane helices predicted by TMHMM2.0
228410006984	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
228410006985	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410006986	active site
228410006987	phosphorylation site [posttranslational modification]
228410006988	intermolecular recognition site; other site
228410006989	dimerization interface [polypeptide binding]; other site
228410006990	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
228410006991	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
228410006992	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
228410006993	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
228410006994	Protein of unknown function (DUF2909); Region: DUF2909; pfam11137
228410006995	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.745 at residue 20
228410006996	2 probable transmembrane helices predicted by TMHMM2.0
228410006997	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
228410006998	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
228410006999	putative active site [active]
228410007000	putative PHP Thumb interface [polypeptide binding]; other site
228410007001	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
228410007002	generic binding surface II; other site
228410007003	generic binding surface I; other site
228410007004	putative protease; Provisional; Region: PRK15452
228410007005	Peptidase family U32; Region: Peptidase_U32; pfam01136
228410007006	shikimate kinase; Reviewed; Region: aroK; PRK00131
228410007007	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
228410007008	ADP binding site [chemical binding]; other site
228410007009	magnesium binding site [ion binding]; other site
228410007010	putative shikimate binding site; other site
228410007011	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
228410007012	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
228410007013	active site
228410007014	dimer interface [polypeptide binding]; other site
228410007015	metal binding site [ion binding]; metal-binding site
228410007016	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
228410007017	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
228410007018	Zn2+ binding site [ion binding]; other site
228410007019	Mg2+ binding site [ion binding]; other site
228410007020	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
228410007021	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
228410007022	Sel1-like repeats; Region: SEL1; smart00671
228410007023	Sel1-like repeats; Region: SEL1; smart00671
228410007024	Sel1-like repeats; Region: SEL1; smart00671
228410007025	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.385 at residue 19
228410007026	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
228410007027	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
228410007028	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
228410007029	8 probable transmembrane helices predicted by TMHMM2.0
228410007030	3 probable transmembrane helices predicted by TMHMM2.0
228410007031	3 probable transmembrane helices predicted by TMHMM2.0
228410007032	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.883) with cleavage site probability 0.199 at residue 21
228410007033	NE1987 and NE1988 are 2 parts of a pseudogene caused by a frameshift
228410007034	NE1987 and NE1988 are 2 parts of a dead gene due to a frameshift;TonB-dependent receptor protein
228410007035	NE1987 and NE1988 are 2 parts of a dead gene due to a frameshift; tonB-dependent receptor protein
228410007036	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410007037	FecR protein; Region: FecR; pfam04773
228410007038	1 probable transmembrane helix predicted by TMHMM2.0
228410007039	ISNE5
228410007040	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410007041	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410007042	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410007043	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
228410007044	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410007045	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410007046	DNA binding residues [nucleotide binding]
228410007047	Bacterial transcriptional activator domain; Region: BTAD; smart01043
228410007048	ISNE3
228410007049	putative transposase OrfB; Reviewed; Region: PHA02517
228410007050	HTH-like domain; Region: HTH_21; pfam13276
228410007051	Integrase core domain; Region: rve; pfam00665
228410007052	Integrase core domain; Region: rve_3; pfam13683
228410007053	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
228410007054	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
228410007055	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.613) with cleavage site probability 0.570 at residue 39
228410007056	1 probable transmembrane helix predicted by TMHMM2.0
228410007057	putative regulator PrlF; Provisional; Region: PRK09974
228410007058	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
228410007059	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
228410007060	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
228410007061	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
228410007062	NAD(P) binding site [chemical binding]; other site
228410007063	catalytic residues [active]
228410007064	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
228410007065	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.846) with cleavage site probability 0.248 at residue 21
228410007066	7 probable transmembrane helices predicted by TMHMM2.0
228410007067	Cytochrome c; Region: Cytochrom_C; pfam00034
228410007068	1 probable transmembrane helix predicted by TMHMM2.0
228410007069	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
228410007070	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
228410007071	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
228410007072	Putative water exit pathway; other site
228410007073	Binuclear center (active site) [active]
228410007074	K-pathway; other site
228410007075	Putative proton exit pathway; other site
228410007076	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.931) with cleavage site probability 0.700 at residue 31
228410007077	12 probable transmembrane helices predicted by TMHMM2.0
228410007078	MoxR-like ATPases [General function prediction only]; Region: COG0714
228410007079	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410007080	Walker A motif; other site
228410007081	ATP binding site [chemical binding]; other site
228410007082	Walker B motif; other site
228410007083	CbbQ/NirQ/NorQ C-terminal; Region: CbbQ_C; pfam08406
228410007084	Nitric oxide reductase activation protein [Inorganic ion transport and metabolism]; Region: NorD; COG4548
228410007085	norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role  in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454
228410007086	metal ion-dependent adhesion site (MIDAS); other site
228410007087	NE2008 and NE2009 are parts of a large pseudogene caused by multiple premature stops and/or frameshifts. The 5' end of the pseudogene is no longer detectable.
228410007088	NE2008 and NE2009 are remnants of a dead, large extracellular protease gene; adhesin aida-I
228410007089	NE2008 and NE2009 are remnants of a dead, large extracellular protease gene;possible serine proteinase
228410007090	ISNE5
228410007091	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410007092	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410007093	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410007094	ISNE2
228410007095	Winged helix-turn helix; Region: HTH_29; pfam13551
228410007096	Integrase core domain; Region: rve; pfam00665
228410007097	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410007098	Integrase core domain; Region: rve_3; pfam13683
228410007099	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410007100	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
228410007101	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
228410007102	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
228410007103	probable O-glycosylation ligase, exosortase A-associated; Region: PEP_O_lig_1; TIGR03097
228410007104	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.943) with cleavage site probability 0.197 at residue 20
228410007105	10 probable transmembrane helices predicted by TMHMM2.0
228410007106	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
228410007107	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
228410007108	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
228410007109	active site
228410007110	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
228410007111	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
228410007112	active site
228410007113	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
228410007114	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
228410007115	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
228410007116	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
228410007117	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
228410007118	colanic acid exporter; Provisional; Region: PRK10459
228410007119	12 probable transmembrane helices predicted by TMHMM2.0
228410007120	ISNE5
228410007121	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410007122	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410007123	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410007124	part of dead transposon from 2187413..2188287; transposase
228410007125	part of dead transposon from 2187413..2188287; transposase
228410007126	5' remnant of gene interrupted by an IS element;conserved hypothetical protein
228410007127	Winged helix-turn helix; Region: HTH_29; pfam13551
228410007128	Integrase core domain; Region: rve; pfam00665
228410007129	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410007130	Integrase core domain; Region: rve_3; pfam13683
228410007131	ISNE2
228410007132	glycogen branching enzyme; Provisional; Region: PRK05402
228410007133	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
228410007134	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
228410007135	active site
228410007136	catalytic site [active]
228410007137	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
228410007138	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
228410007139	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
228410007140	ligand binding site; other site
228410007141	oligomer interface; other site
228410007142	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
228410007143	dimer interface [polypeptide binding]; other site
228410007144	N-terminal domain interface [polypeptide binding]; other site
228410007145	sulfate 1 binding site; other site
228410007146	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
228410007147	N-terminal catalytic domain of thermoactive amylopullulanases; glycoside hydrolase family 57 (GH57); Region: GH57N_APU; cd10796
228410007148	putative active site [active]
228410007149	catalytic site [active]
228410007150	N-terminal catalytic domain of 4-alpha-glucanotransferase; glycoside hydrolase family 57 (GH57); Region: GH57N_TLGT_like; cd10793
228410007151	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
228410007152	active site
228410007153	catalytic site [active]
228410007154	homodimer interface [polypeptide binding]; other site
228410007155	Lid 1; other site
228410007156	Domain of unknown function (DUF1925); Region: DUF1925; pfam09094
228410007157	Domain of unknown function (DUF1926); Region: DUF1926; pfam09095
228410007158	Mannosyl oligosaccharide glucosidase; Region: Glyco_hydro_63; pfam03200
228410007159	putative inner membrane protein; Provisional; Region: PRK11099
228410007160	10 probable transmembrane helices predicted by TMHMM2.0
228410007161	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
228410007162	CPxP  motif; other site
228410007163	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
228410007164	11 probable transmembrane helices predicted by TMHMM2.0
228410007165	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
228410007166	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
228410007167	HlyD family secretion protein; Region: HlyD_3; pfam13437
228410007168	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.382 at residue 22
228410007169	Uncharacterized bacterial family of heme peroxidases; Region: An_peroxidase_bacterial_1; cd09819
228410007170	putative heme binding site [chemical binding]; other site
228410007171	putative substrate binding site [chemical binding]; other site
228410007172	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.689) with cleavage site probability 0.449 at residue 23
228410007173	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
228410007174	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
228410007175	ATP binding site [chemical binding]; other site
228410007176	Mg++ binding site [ion binding]; other site
228410007177	motif III; other site
228410007178	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410007179	nucleotide binding region [chemical binding]; other site
228410007180	ATP-binding site [chemical binding]; other site
228410007181	8 probable transmembrane helices predicted by TMHMM2.0
228410007182	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
228410007183	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.622 at residue 25
228410007184	1 probable transmembrane helix predicted by TMHMM2.0
228410007185	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
228410007186	Seven times multi-haem cytochrome CxxCH; Region: Multi-haem_cyto; pfam13447
228410007187	1 probable transmembrane helix predicted by TMHMM2.0
228410007188	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.985 at residue 25
228410007189	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
228410007190	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
228410007191	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
228410007192	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
228410007193	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
228410007194	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
228410007195	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
228410007196	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
228410007197	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
228410007198	DNA binding site [nucleotide binding]
228410007199	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
228410007200	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
228410007201	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
228410007202	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
228410007203	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
228410007204	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
228410007205	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
228410007206	RPB3 interaction site [polypeptide binding]; other site
228410007207	RPB1 interaction site [polypeptide binding]; other site
228410007208	RPB11 interaction site [polypeptide binding]; other site
228410007209	RPB10 interaction site [polypeptide binding]; other site
228410007210	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.813) with cleavage site probability 0.627 at residue 35
228410007211	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
228410007212	peripheral dimer interface [polypeptide binding]; other site
228410007213	core dimer interface [polypeptide binding]; other site
228410007214	L10 interface [polypeptide binding]; other site
228410007215	L11 interface [polypeptide binding]; other site
228410007216	putative EF-Tu interaction site [polypeptide binding]; other site
228410007217	putative EF-G interaction site [polypeptide binding]; other site
228410007218	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
228410007219	23S rRNA interface [nucleotide binding]; other site
228410007220	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
228410007221	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
228410007222	mRNA/rRNA interface [nucleotide binding]; other site
228410007223	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
228410007224	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
228410007225	23S rRNA interface [nucleotide binding]; other site
228410007226	L7/L12 interface [polypeptide binding]; other site
228410007227	putative thiostrepton binding site; other site
228410007228	L25 interface [polypeptide binding]; other site
228410007229	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
228410007230	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
228410007231	putative homodimer interface [polypeptide binding]; other site
228410007232	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
228410007233	heterodimer interface [polypeptide binding]; other site
228410007234	homodimer interface [polypeptide binding]; other site
228410007235	elongation factor Tu; Reviewed; Region: PRK00049
228410007236	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
228410007237	G1 box; other site
228410007238	GEF interaction site [polypeptide binding]; other site
228410007239	GTP/Mg2+ binding site [chemical binding]; other site
228410007240	Switch I region; other site
228410007241	G2 box; other site
228410007242	G3 box; other site
228410007243	Switch II region; other site
228410007244	G4 box; other site
228410007245	G5 box; other site
228410007246	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
228410007247	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
228410007248	Antibiotic Binding Site [chemical binding]; other site
228410007249	elongation factor G; Reviewed; Region: PRK00007
228410007250	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
228410007251	G1 box; other site
228410007252	putative GEF interaction site [polypeptide binding]; other site
228410007253	GTP/Mg2+ binding site [chemical binding]; other site
228410007254	Switch I region; other site
228410007255	G2 box; other site
228410007256	G3 box; other site
228410007257	Switch II region; other site
228410007258	G4 box; other site
228410007259	G5 box; other site
228410007260	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
228410007261	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
228410007262	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
228410007263	30S ribosomal protein S7; Validated; Region: PRK05302
228410007264	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
228410007265	S17 interaction site [polypeptide binding]; other site
228410007266	S8 interaction site; other site
228410007267	16S rRNA interaction site [nucleotide binding]; other site
228410007268	streptomycin interaction site [chemical binding]; other site
228410007269	23S rRNA interaction site [nucleotide binding]; other site
228410007270	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
228410007271	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
228410007272	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
228410007273	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.471 at residue 24
228410007274	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.854 at residue 24
228410007275	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
228410007276	Cytochrome c; Region: Cytochrom_C; pfam00034
228410007277	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
228410007278	10 probable transmembrane helices predicted by TMHMM2.0
228410007279	CopC domain; Region: CopC; pfam04234
228410007280	1 probable transmembrane helix predicted by TMHMM2.0
228410007281	1 probable transmembrane helix predicted by TMHMM2.0
228410007282	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.482 at residue 30
228410007283	2 probable transmembrane helices predicted by TMHMM2.0
228410007284	methane monooxygenase/ammonia monooxygenase, subunit B; Region: CH4_NH3mon_ox_B; TIGR03079
228410007285	Monooxygenase subunit B protein; Region: Monooxygenase_B; pfam04744
228410007286	3 probable transmembrane helices predicted by TMHMM2.0
228410007287	methane monooxygenase/ammonia monooxygenase, subunit A; Region: CH4_NH3mon_ox_A; TIGR03080
228410007288	6 probable transmembrane helices predicted by TMHMM2.0
228410007289	Ammonia monooxygenase/methane monooxygenase, subunit C; Region: AmoC; pfam04896
228410007290	6 probable transmembrane helices predicted by TMHMM2.0
228410007291	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
228410007292	rare lipoprotein A; Region: rlpA; TIGR00413
228410007293	Sporulation related domain; Region: SPOR; pfam05036
228410007294	1 probable transmembrane helix predicted by TMHMM2.0
228410007295	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
228410007296	10 probable transmembrane helices predicted by TMHMM2.0
228410007297	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
228410007298	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
228410007299	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
228410007300	1 probable transmembrane helix predicted by TMHMM2.0
228410007301	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
228410007302	4 probable transmembrane helices predicted by TMHMM2.0
228410007303	rod shape-determining protein MreC; Provisional; Region: PRK13922
228410007304	rod shape-determining protein MreC; Region: MreC; pfam04085
228410007305	rod shape-determining protein MreB; Provisional; Region: PRK13927
228410007306	MreB and similar proteins; Region: MreB_like; cd10225
228410007307	nucleotide binding site [chemical binding]; other site
228410007308	Mg binding site [ion binding]; other site
228410007309	putative protofilament interaction site [polypeptide binding]; other site
228410007310	RodZ interaction site [polypeptide binding]; other site
228410007311	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
228410007312	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
228410007313	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
228410007314	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
228410007315	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
228410007316	GatB domain; Region: GatB_Yqey; smart00845
228410007317	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
228410007318	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
228410007319	putative dimer interface [polypeptide binding]; other site
228410007320	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
228410007321	CHASE2 domain; Region: CHASE2; pfam05226
228410007322	PAS fold; Region: PAS; pfam00989
228410007323	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
228410007324	putative active site [active]
228410007325	heme pocket [chemical binding]; other site
228410007326	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
228410007327	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
228410007328	metal binding site [ion binding]; metal-binding site
228410007329	active site
228410007330	I-site; other site
228410007331	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
228410007332	2 probable transmembrane helices predicted by TMHMM2.0
228410007333	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.944) with cleavage site probability 0.401 at residue 34
228410007334	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4254
228410007335	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
228410007336	FecR protein; Region: FecR; pfam04773
228410007337	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
228410007338	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
228410007339	Flagellar regulator YcgR; Region: YcgR; pfam07317
228410007340	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
228410007341	PilZ domain; Region: PilZ; pfam07238
228410007342	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
228410007343	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
228410007344	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410007345	active site
228410007346	phosphorylation site [posttranslational modification]
228410007347	intermolecular recognition site; other site
228410007348	dimerization interface [polypeptide binding]; other site
228410007349	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410007350	Walker A motif; other site
228410007351	ATP binding site [chemical binding]; other site
228410007352	Walker B motif; other site
228410007353	arginine finger; other site
228410007354	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
228410007355	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
228410007356	PAS domain; Region: PAS; smart00091
228410007357	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
228410007358	phosphorylation site [posttranslational modification]
228410007359	dimer interface [polypeptide binding]; other site
228410007360	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
228410007361	ATP binding site [chemical binding]; other site
228410007362	Mg2+ binding site [ion binding]; other site
228410007363	G-X-G motif; other site
228410007364	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
228410007365	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
228410007366	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
228410007367	1 probable transmembrane helix predicted by TMHMM2.0
228410007368	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
228410007369	FliG C-terminal domain; Region: FliG_C; pfam01706
228410007370	flagellar assembly protein H; Validated; Region: fliH; PRK05687
228410007371	Flagellar assembly protein FliH; Region: FliH; pfam02108
228410007372	flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496
228410007373	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
228410007374	Walker A motif/ATP binding site; other site
228410007375	Walker B motif; other site
228410007376	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
228410007377	flagellar export protein FliJ; Region: flagell_FliJ; TIGR02473
228410007378	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
228410007379	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
228410007380	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
228410007381	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
228410007382	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410007383	binding surface
228410007384	TPR motif; other site
228410007385	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
228410007386	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410007387	binding surface
228410007388	Tetratricopeptide repeat; Region: TPR_16; pfam13432
228410007389	TPR motif; other site
228410007390	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
228410007391	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
228410007392	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
228410007393	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
228410007394	SIR2-like domain; Region: SIR2_2; pfam13289
228410007395	Domain of unknown function DUF87; Region: DUF87; pfam01935
228410007396	AAA-like domain; Region: AAA_10; pfam12846
228410007397	ISNE3
228410007398	Integrase core domain; Region: rve; pfam00665
228410007399	Integrase core domain; Region: rve_3; pfam13683
228410007400	ISNE8
228410007401	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
228410007402	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
228410007403	putative active site [active]
228410007404	putative NTP binding site [chemical binding]; other site
228410007405	putative nucleic acid binding site [nucleotide binding]; other site
228410007406	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
228410007407	MTH538 TIR-like domain (DUF1863); Region: DUF1863; pfam08937
228410007408	3 probable transmembrane helices predicted by TMHMM2.0
228410007409	putative transposase OrfB; Reviewed; Region: PHA02517
228410007410	Domain of unknown function (DUF4415); Region: DUF4415; pfam14384
228410007411	Protein of unknown function (DUF497); Region: DUF497; cl01108
228410007412	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
228410007413	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
228410007414	RES domain; Region: RES; pfam08808
228410007415	ISNE3
228410007416	putative transposase OrfB; Reviewed; Region: PHA02517
228410007417	HTH-like domain; Region: HTH_21; pfam13276
228410007418	Integrase core domain; Region: rve; pfam00665
228410007419	Integrase core domain; Region: rve_3; pfam13683
228410007420	Fic family protein [Function unknown]; Region: COG3177
228410007421	Fic/DOC family; Region: Fic; pfam02661
228410007422	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
228410007423	1 probable transmembrane helix predicted by TMHMM2.0
228410007424	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
228410007425	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
228410007426	oligomeric interface; other site
228410007427	putative active site [active]
228410007428	homodimer interface [polypeptide binding]; other site
228410007429	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
228410007430	putative active site [active]
228410007431	homotetrameric interface [polypeptide binding]; other site
228410007432	metal binding site [ion binding]; metal-binding site
228410007433	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
228410007434	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
228410007435	dead gene, half the gene is missing;conserved hypothetical protein
228410007436	NE2117 and NE2118 are 2 parts of a pseudogene caused by a frameshift
228410007437	NE2117 and NE2118 are 2 parts of a dead gene due to a frameshift;conserved hypothetical protein
228410007438	NE2117 and NE2118 are 2 parts of a dead gene due to a frameshift;conserved hypothetical protein
228410007439	Fic family protein [Function unknown]; Region: COG3177
228410007440	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
228410007441	Fic/DOC family; Region: Fic; pfam02661
228410007442	The other half of this pseudogene is modeled as NE1391 at position complement(1518978..1519682);Phosphoribosyl transferase
228410007443	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.858) with cleavage site probability 0.428 at residue 33
228410007444	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
228410007445	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
228410007446	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK06978
228410007447	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
228410007448	dimerization interface [polypeptide binding]; other site
228410007449	active site
228410007450	1 probable transmembrane helix predicted by TMHMM2.0
228410007451	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
228410007452	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
228410007453	active site
228410007454	FMN binding site [chemical binding]; other site
228410007455	substrate binding site [chemical binding]; other site
228410007456	3Fe-4S cluster binding site [ion binding]; other site
228410007457	Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774
228410007458	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410007459	N-terminal plug; other site
228410007460	ligand-binding site [chemical binding]; other site
228410007461	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.978) with cleavage site probability 0.381 at residue 27
228410007462	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
228410007463	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
228410007464	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
228410007465	active site
228410007466	substrate binding site [chemical binding]; other site
228410007467	FMN binding site [chemical binding]; other site
228410007468	putative catalytic residues [active]
228410007469	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
228410007470	5 probable transmembrane helices predicted by TMHMM2.0
228410007471	NE2128 and NE2129 are 2 parts of a pseudogene caused by a frameshift
228410007472	NE2128 and NE2129 are 2 parts of a dead gene due to a frameshift;Carbohydrate kinase, FGGY family
228410007473	NE2128 and NE2129 are 2 parts of a dead gene due to a frameshift;Carbohydrate kinase, FGGY family
228410007474	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
228410007475	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
228410007476	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
228410007477	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
228410007478	active site
228410007479	phosphorylation site [posttranslational modification]
228410007480	intermolecular recognition site; other site
228410007481	dimerization interface [polypeptide binding]; other site
228410007482	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
228410007483	DNA binding site [nucleotide binding]
228410007484	aspartate kinase; Reviewed; Region: PRK06635
228410007485	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
228410007486	putative nucleotide binding site [chemical binding]; other site
228410007487	putative catalytic residues [active]
228410007488	putative Mg ion binding site [ion binding]; other site
228410007489	putative aspartate binding site [chemical binding]; other site
228410007490	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
228410007491	putative allosteric regulatory site; other site
228410007492	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
228410007493	putative allosteric regulatory residue; other site
228410007494	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
228410007495	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.956) with cleavage site probability 0.422 at residue 27
228410007496	propionate/acetate kinase; Provisional; Region: PRK12379
228410007497	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
228410007498	putative phosphoketolase; Provisional; Region: PRK05261
228410007499	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
228410007500	TPP-binding site; other site
228410007501	XFP C-terminal domain; Region: XFP_C; pfam09363
228410007502	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
228410007503	putative active site [active]
228410007504	transaldolase; Provisional; Region: PRK03903
228410007505	catalytic residue [active]
228410007506	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
228410007507	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.503 at residue 19
228410007508	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
228410007509	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410007510	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410007511	DNA binding residues [nucleotide binding]
228410007512	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
228410007513	FecR protein; Region: FecR; pfam04773
228410007514	1 probable transmembrane helix predicted by TMHMM2.0
228410007515	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410007516	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410007517	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410007518	N-terminal plug; other site
228410007519	ligand-binding site [chemical binding]; other site
228410007520	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.956 at residue 22
228410007521	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
228410007522	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
228410007523	8 probable transmembrane helices predicted by TMHMM2.0
228410007524	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
228410007525	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
228410007526	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
228410007527	RNA binding surface [nucleotide binding]; other site
228410007528	Pirin-related protein [General function prediction only]; Region: COG1741
228410007529	Pirin; Region: Pirin; pfam02678
228410007530	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
228410007531	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
228410007532	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.582 at residue 20
228410007533	2 probable transmembrane helices predicted by TMHMM2.0
228410007534	proline aminopeptidase P II; Provisional; Region: PRK10879
228410007535	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
228410007536	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
228410007537	active site
228410007538	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
228410007539	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
228410007540	substrate binding site [chemical binding]; other site
228410007541	hexamer interface [polypeptide binding]; other site
228410007542	metal binding site [ion binding]; metal-binding site
228410007543	phosphoglycolate phosphatase; Provisional; Region: PRK13222
228410007544	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410007545	motif II; other site
228410007546	anthranilate synthase component I; Provisional; Region: PRK13565
228410007547	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
228410007548	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
228410007549	Predicted membrane protein (DUF2231); Region: DUF2231; cl01730
228410007550	4 probable transmembrane helices predicted by TMHMM2.0
228410007551	4 probable transmembrane helices predicted by TMHMM2.0
228410007552	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.952) with cleavage site probability 0.409 at residue 26
228410007553	Predicted transcriptional regulator [Transcription]; Region: COG2345
228410007554	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
228410007555	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
228410007556	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.882 at residue 28
228410007557	ISNE3
228410007558	putative transposase OrfB; Reviewed; Region: PHA02517
228410007559	HTH-like domain; Region: HTH_21; pfam13276
228410007560	Integrase core domain; Region: rve; pfam00665
228410007561	Integrase core domain; Region: rve_3; pfam13683
228410007562	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
228410007563	E3 interaction surface; other site
228410007564	lipoyl attachment site [posttranslational modification]; other site
228410007565	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
228410007566	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
228410007567	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410007568	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
228410007569	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
228410007570	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
228410007571	putative catalytic cysteine [active]
228410007572	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
228410007573	TPR motif; other site
228410007574	binding surface
228410007575	TPR repeat; Region: TPR_11; pfam13414
228410007576	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.500 at residue 27
228410007577	1 probable transmembrane helix predicted by TMHMM2.0
228410007578	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
228410007579	exosortase A system-associated hydrolase 1; Region: hydr1_PEP; TIGR03100
228410007580	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
228410007581	exosortase A system-associated hydrolase 2; Region: hydr2_PEP; TIGR03101
228410007582	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
228410007583	tetraacyldisaccharide 4'-kinase; Provisional; Region: PRK01906
228410007584	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
228410007585	Uncharacterized conserved protein [Function unknown]; Region: COG2835
228410007586	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410007587	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410007588	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410007589	N-terminal plug; other site
228410007590	ligand-binding site [chemical binding]; other site
228410007591	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
228410007592	Part of AAA domain; Region: AAA_19; pfam13245
228410007593	Family description; Region: UvrD_C_2; pfam13538
228410007594	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
228410007595	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
228410007596	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
228410007597	inhibitor-cofactor binding pocket; inhibition site
228410007598	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410007599	catalytic residue [active]
228410007600	13 probable transmembrane helices predicted by TMHMM2.0
228410007601	Methyltransferase domain; Region: Methyltransf_23; pfam13489
228410007602	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410007603	S-adenosylmethionine binding site [chemical binding]; other site
228410007604	GtrA-like protein; Region: GtrA; pfam04138
228410007605	4 probable transmembrane helices predicted by TMHMM2.0
228410007606	Formyltransferase, catalytic core domain; Region: FMT_core; cd08369
228410007607	active site
228410007608	substrate binding site [chemical binding]; other site
228410007609	cosubstrate binding site; other site
228410007610	catalytic site [active]
228410007611	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410007612	S-adenosylmethionine binding site [chemical binding]; other site
228410007613	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
228410007614	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
228410007615	Ligand binding site; other site
228410007616	Putative Catalytic site; other site
228410007617	DXD motif; other site
228410007618	2 probable transmembrane helices predicted by TMHMM2.0
228410007619	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
228410007620	putative active site [active]
228410007621	Protein of unknown function (DUF2281); Region: DUF2281; pfam10047
228410007622	WbqC-like protein family; Region: WbqC; pfam08889
228410007623	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; cl09823
228410007624	10 probable transmembrane helices predicted by TMHMM2.0
228410007625	probable DNA repair protein; Region: TIGR03623
228410007626	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
228410007627	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.926) with cleavage site probability 0.517 at residue 23
228410007628	1 probable transmembrane helix predicted by TMHMM2.0
228410007629	DNA polymerase III subunit delta'; Validated; Region: PRK06964
228410007630	thymidylate kinase; Validated; Region: tmk; PRK00698
228410007631	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
228410007632	TMP-binding site; other site
228410007633	ATP-binding site [chemical binding]; other site
228410007634	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
228410007635	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
228410007636	amidase catalytic site [active]
228410007637	Zn binding residues [ion binding]; other site
228410007638	substrate binding site [chemical binding]; other site
228410007639	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
228410007640	active pocket/dimerization site; other site
228410007641	active site
228410007642	phosphorylation site [posttranslational modification]
228410007643	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
228410007644	dimerization domain swap beta strand [polypeptide binding]; other site
228410007645	regulatory protein interface [polypeptide binding]; other site
228410007646	active site
228410007647	regulatory phosphorylation site [posttranslational modification]; other site
228410007648	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
228410007649	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
228410007650	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
228410007651	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
228410007652	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
228410007653	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
228410007654	Methyltransferase domain; Region: Methyltransf_31; pfam13847
228410007655	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410007656	S-adenosylmethionine binding site [chemical binding]; other site
228410007657	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
228410007658	1 probable transmembrane helix predicted by TMHMM2.0
228410007659	integron integrase; Region: integrase_gron; TIGR02249
228410007660	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
228410007661	Int/Topo IB signature motif; other site
228410007662	ISNE8
228410007663	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
228410007664	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
228410007665	putative active site [active]
228410007666	putative NTP binding site [chemical binding]; other site
228410007667	putative nucleic acid binding site [nucleotide binding]; other site
228410007668	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
228410007669	muropeptide transporter; Reviewed; Region: ampG; PRK11902
228410007670	AmpG-like permease; Region: 2A0125; TIGR00901
228410007671	9 probable transmembrane helices predicted by TMHMM2.0
228410007672	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
228410007673	putative active site [active]
228410007674	putative catalytic site [active]
228410007675	putative DNA binding site [nucleotide binding]; other site
228410007676	putative phosphate binding site [ion binding]; other site
228410007677	metal binding site A [ion binding]; metal-binding site
228410007678	putative AP binding site [nucleotide binding]; other site
228410007679	putative metal binding site B [ion binding]; other site
228410007680	hypothetical protein; Provisional; Region: PRK05255
228410007681	peptidase PmbA; Provisional; Region: PRK11040
228410007682	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
228410007683	EamA-like transporter family; Region: EamA; pfam00892
228410007684	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.632) with cleavage site probability 0.135 at residue 53
228410007685	8 probable transmembrane helices predicted by TMHMM2.0
228410007686	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
228410007687	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
228410007688	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
228410007689	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
228410007690	RNA binding site [nucleotide binding]; other site
228410007691	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
228410007692	3 probable transmembrane helices predicted by TMHMM2.0
228410007693	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.975) with cleavage site probability 0.769 at residue 18
228410007694	Flavin-binding monooxygenase-like; Region: FMO-like; pfam00743
228410007695	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
228410007696	ISNE4
228410007697	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410007698	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410007699	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410007700	NE2202 and NE2203 are 2 parts of a pseudogene caused by a frameshift
228410007701	NE2202 and NE2203 are 2 parts of a dead gene due to a frameshift;conserved hypothetical protein
228410007702	NE2202 and NE2203 are 2 parts of a dead gene due to a frameshift;Carbon-nitrogen hydrolase:Rhodanese/cdc25 fold
228410007703	NE2204 and an unannotated ORF overlapping its 3' end are two parts of a pseudogene caused by a frameshift
228410007704	NE2204 and an unannotated ORF overlapping the 3' end are 2 parts of a dead gene due to a frameshift;possible transcriptional regulator
228410007705	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
228410007706	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
228410007707	NAD binding site [chemical binding]; other site
228410007708	homotetramer interface [polypeptide binding]; other site
228410007709	homodimer interface [polypeptide binding]; other site
228410007710	substrate binding site [chemical binding]; other site
228410007711	active site
228410007712	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.626) with cleavage site probability 0.422 at residue 22
228410007713	SurA N-terminal domain; Region: SurA_N_3; cl07813
228410007714	periplasmic folding chaperone; Provisional; Region: PRK10788
228410007715	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
228410007716	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.767) with cleavage site probability 0.487 at residue 31
228410007717	1 probable transmembrane helix predicted by TMHMM2.0
228410007718	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
228410007719	IHF dimer interface [polypeptide binding]; other site
228410007720	IHF - DNA interface [nucleotide binding]; other site
228410007721	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
228410007722	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
228410007723	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
228410007724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3807
228410007725	Bacterial SH3 domain; Region: SH3_4; pfam06347
228410007726	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.513 at residue 17
228410007727	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.970) with cleavage site probability 0.809 at residue 32
228410007728	1 probable transmembrane helix predicted by TMHMM2.0
228410007729	preprotein translocase subunit SecB; Validated; Region: PRK05751
228410007730	SecA binding site; other site
228410007731	Preprotein binding site; other site
228410007732	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
228410007733	GSH binding site [chemical binding]; other site
228410007734	catalytic residues [active]
228410007735	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
228410007736	active site residue [active]
228410007737	1 probable transmembrane helix predicted by TMHMM2.0
228410007738	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
228410007739	heterotetramer interface [polypeptide binding]; other site
228410007740	active site pocket [active]
228410007741	cleavage site
228410007742	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG2607
228410007743	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410007744	Walker A motif; other site
228410007745	ATP binding site [chemical binding]; other site
228410007746	Walker B motif; other site
228410007747	arginine finger; other site
228410007748	hypothetical protein; Provisional; Region: PRK08999
228410007749	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
228410007750	active site
228410007751	8-oxo-dGMP binding site [chemical binding]; other site
228410007752	nudix motif; other site
228410007753	metal binding site [ion binding]; metal-binding site
228410007754	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
228410007755	thiamine phosphate binding site [chemical binding]; other site
228410007756	active site
228410007757	pyrophosphate binding site [ion binding]; other site
228410007758	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
228410007759	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410007760	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
228410007761	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
228410007762	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
228410007763	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
228410007764	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.952) with cleavage site probability 0.421 at residue 23
228410007765	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
228410007766	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
228410007767	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
228410007768	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.976) with cleavage site probability 0.747 at residue 33
228410007769	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
228410007770	arginyl-tRNA-protein transferase; Provisional; Region: PRK01305
228410007771	Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376
228410007772	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
228410007773	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
228410007774	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
228410007775	quinone interaction residues [chemical binding]; other site
228410007776	active site
228410007777	catalytic residues [active]
228410007778	FMN binding site [chemical binding]; other site
228410007779	substrate binding site [chemical binding]; other site
228410007780	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.741) with cleavage site probability 0.389 at residue 19
228410007781	ferredoxin; Provisional; Region: PRK08764
228410007782	Putative Fe-S cluster; Region: FeS; pfam04060
228410007783	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
228410007784	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
228410007785	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
228410007786	minor groove reading motif; other site
228410007787	helix-hairpin-helix signature motif; other site
228410007788	substrate binding pocket [chemical binding]; other site
228410007789	active site
228410007790	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
228410007791	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
228410007792	active site
228410007793	NTP binding site [chemical binding]; other site
228410007794	metal binding triad [ion binding]; metal-binding site
228410007795	antibiotic binding site [chemical binding]; other site
228410007796	Protein of unknown function DUF86; Region: DUF86; pfam01934
228410007797	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
228410007798	Sel1-like repeats; Region: SEL1; smart00671
228410007799	Sel1-like repeats; Region: SEL1; smart00671
228410007800	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
228410007801	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
228410007802	N-acetyl-D-glucosamine binding site [chemical binding]; other site
228410007803	catalytic residue [active]
228410007804	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.715 at residue 23
228410007805	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
228410007806	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
228410007807	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
228410007808	Transporter associated domain; Region: CorC_HlyC; smart01091
228410007809	6 probable transmembrane helices predicted by TMHMM2.0
228410007810	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.958) with cleavage site probability 0.939 at residue 27
228410007811	ISNE1
228410007812	Winged helix-turn helix; Region: HTH_29; pfam13551
228410007813	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410007814	Homeodomain-like domain; Region: HTH_32; pfam13565
228410007815	Integrase core domain; Region: rve; pfam00665
228410007816	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410007817	Integrase core domain; Region: rve_3; pfam13683
228410007818	hypothetical protein; Provisional; Region: PRK14852
228410007819	Haemagglutinin; Region: Hemagglutinin; pfam00509
228410007820	1 probable transmembrane helix predicted by TMHMM2.0
228410007821	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
228410007822	active site
228410007823	NTP binding site [chemical binding]; other site
228410007824	metal binding triad [ion binding]; metal-binding site
228410007825	antibiotic binding site [chemical binding]; other site
228410007826	ISNE1
228410007827	Winged helix-turn helix; Region: HTH_29; pfam13551
228410007828	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410007829	Homeodomain-like domain; Region: HTH_32; pfam13565
228410007830	Integrase core domain; Region: rve; pfam00665
228410007831	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410007832	Integrase core domain; Region: rve_3; pfam13683
228410007833	Fatty acid desaturase; Region: FA_desaturase; pfam00487
228410007834	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
228410007835	putative di-iron ligands [ion binding]; other site
228410007836	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
228410007837	3 probable transmembrane helices predicted by TMHMM2.0
228410007838	Pseudomonas fluorescens MupV-like, extended (e) SDRs; Region: MupV_like_SDR_e; cd05263
228410007839	putative NAD(P) binding site [chemical binding]; other site
228410007840	active site
228410007841	putative substrate binding site [chemical binding]; other site
228410007842	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
228410007843	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
228410007844	acyl-activating enzyme (AAE) consensus motif; other site
228410007845	putative AMP binding site [chemical binding]; other site
228410007846	putative active site [active]
228410007847	putative CoA binding site [chemical binding]; other site
228410007848	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
228410007849	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
228410007850	Ligand Binding Site [chemical binding]; other site
228410007851	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
228410007852	FAD binding domain; Region: FAD_binding_4; pfam01565
228410007853	Transposase IS200 like; Region: Y1_Tnp; pfam01797
228410007854	1 probable transmembrane helix predicted by TMHMM2.0
228410007855	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.941) with cleavage site probability 0.381 at residue 30
228410007856	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
228410007857	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410007858	4 probable transmembrane helices predicted by TMHMM2.0
228410007859	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.648 at residue 20
228410007860	1 probable transmembrane helix predicted by TMHMM2.0
228410007861	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
228410007862	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
228410007863	FtsX-like permease family; Region: FtsX; pfam02687
228410007864	4 probable transmembrane helices predicted by TMHMM2.0
228410007865	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.808 at residue 36
228410007866	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
228410007867	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
228410007868	Walker A/P-loop; other site
228410007869	ATP binding site [chemical binding]; other site
228410007870	Q-loop/lid; other site
228410007871	ABC transporter signature motif; other site
228410007872	Walker B; other site
228410007873	D-loop; other site
228410007874	H-loop/switch region; other site
228410007875	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.503 at residue 26
228410007876	N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated; Region: exosort_acyl; TIGR03694
228410007877	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
228410007878	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.981) with cleavage site probability 0.865 at residue 27
228410007879	1 probable transmembrane helix predicted by TMHMM2.0
228410007880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
228410007881	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
228410007882	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
228410007883	active site
228410007884	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
228410007885	homodimer interface [polypeptide binding]; other site
228410007886	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
228410007887	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
228410007888	Substrate binding site; other site
228410007889	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
228410007890	putative regulatory protein, FmdB family; Region: CxxC_CxxC_SSSS; TIGR02605
228410007891	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
228410007892	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
228410007893	dimer interface [polypeptide binding]; other site
228410007894	anticodon binding site; other site
228410007895	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
228410007896	homodimer interface [polypeptide binding]; other site
228410007897	motif 1; other site
228410007898	active site
228410007899	motif 2; other site
228410007900	GAD domain; Region: GAD; pfam02938
228410007901	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
228410007902	motif 3; other site
228410007903	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
228410007904	nudix motif; other site
228410007905	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
228410007906	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
228410007907	catalytic site [active]
228410007908	G-X2-G-X-G-K; other site
228410007909	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
228410007910	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
228410007911	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
228410007912	Coenzyme A binding pocket [chemical binding]; other site
228410007913	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410007914	S-adenosylmethionine binding site [chemical binding]; other site
228410007915	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_17; cd08356
228410007916	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
228410007917	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
228410007918	potential catalytic triad [active]
228410007919	conserved cys residue [active]
228410007920	ATP-dependent protease subunit HslV; Provisional; Region: PRK05456
228410007921	active site
228410007922	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
228410007923	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410007924	Walker A motif; other site
228410007925	ATP binding site [chemical binding]; other site
228410007926	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
228410007927	Walker B motif; other site
228410007928	arginine finger; other site
228410007929	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
228410007930	beta-ketothiolase; Provisional; Region: PRK09051
228410007931	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
228410007932	dimer interface [polypeptide binding]; other site
228410007933	active site
228410007934	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
228410007935	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
228410007936	active site
228410007937	dimer interface [polypeptide binding]; other site
228410007938	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
228410007939	dimer interface [polypeptide binding]; other site
228410007940	active site
228410007941	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
228410007942	glycogen/starch synthase, ADP-glucose type; Region: glgA; TIGR02095
228410007943	ADP-binding pocket [chemical binding]; other site
228410007944	homodimer interface [polypeptide binding]; other site
228410007945	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.990 at residue 28
228410007946	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
228410007947	putative ADP-binding pocket [chemical binding]; other site
228410007948	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
228410007949	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp2; TIGR03088
228410007950	This family is most closely related to the GT1 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis; Region: GT1_WbnK_like; cd03807
228410007951	putative ADP-binding pocket [chemical binding]; other site
228410007952	Herpesvirus latent membrane protein 1 (LMP1); Region: Herpes_LMP1; pfam05297
228410007953	8 probable transmembrane helices predicted by TMHMM2.0
228410007954	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
228410007955	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
228410007956	putative ADP-binding pocket [chemical binding]; other site
228410007957	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
228410007958	ATP-grasp domain; Region: ATP-grasp_4; cl17255
228410007959	ATP-grasp domain; Region: ATP-grasp_4; cl17255
228410007960	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
228410007961	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
228410007962	putative active site [active]
228410007963	putative metal binding site [ion binding]; other site
228410007964	NE2272 and NE2275 are two parts of a pseudogene caused by the interruption of an IS element
228410007965	NE2272 and NE2275 are 2 parts of a dead gene due to IS element insertion;hypothetical protein
228410007966	4 probable transmembrane helices predicted by TMHMM2.0
228410007967	ISNE4
228410007968	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410007969	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410007970	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410007971	NE2272 and NE2275 are 2 parts of a dead gene due to IS element insertion;Polysaccharide biosynthesis protein
228410007972	7 probable transmembrane helices predicted by TMHMM2.0
228410007973	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
228410007974	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
228410007975	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
228410007976	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
228410007977	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
228410007978	putative NAD(P) binding site [chemical binding]; other site
228410007979	active site
228410007980	putative substrate binding site [chemical binding]; other site
228410007981	Low molecular weight phosphatase family; Region: LMWPc; cd00115
228410007982	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
228410007983	polysaccharide export protein Wza; Provisional; Region: PRK15078
228410007984	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
228410007985	SLBB domain; Region: SLBB; pfam10531
228410007986	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.739) with cleavage site probability 0.252 at residue 21
228410007987	tyrosine kinase; Provisional; Region: PRK11519
228410007988	Chain length determinant protein; Region: Wzz; pfam02706
228410007989	Bacterial type III secretion protein (HrpB7); Region: HrpB7; pfam09486
228410007990	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
228410007991	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
228410007992	2 probable transmembrane helices predicted by TMHMM2.0
228410007993	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
228410007994	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
228410007995	Mg++ binding site [ion binding]; other site
228410007996	putative catalytic motif [active]
228410007997	substrate binding site [chemical binding]; other site
228410007998	10 probable transmembrane helices predicted by TMHMM2.0
228410007999	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
228410008000	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; cl02748
228410008001	ZipA, C-terminal domain (FtsZ-binding); Region: ZipA_C; smart00771
228410008002	FtsZ protein binding site [polypeptide binding]; other site
228410008003	1 probable transmembrane helix predicted by TMHMM2.0
228410008004	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
228410008005	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
228410008006	Walker A/P-loop; other site
228410008007	ATP binding site [chemical binding]; other site
228410008008	Q-loop/lid; other site
228410008009	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
228410008010	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
228410008011	Q-loop/lid; other site
228410008012	ABC transporter signature motif; other site
228410008013	Walker B; other site
228410008014	D-loop; other site
228410008015	H-loop/switch region; other site
228410008016	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
228410008017	fumarate hydratase; Reviewed; Region: fumC; PRK00485
228410008018	Class II fumarases; Region: Fumarase_classII; cd01362
228410008019	active site
228410008020	tetramer interface [polypeptide binding]; other site
228410008021	NE2287 and NE2288 are 2 parts of a pseudogene caused by a frameshift
228410008022	NE2287 and NE2288 are 2 parts of a dead gene due to a frameshift;conserved hypothetical protein
228410008023	NE2287 and NE2288 are 2 parts of a dead gene due to a frameshift;Domain of unknown function 2
228410008024	dead gene, missing 1/3 length and the other gene in the operon is also dead due to frameshift;Domain of unknown function, DUF9
228410008025	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
228410008026	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
228410008027	type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538
228410008028	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
228410008029	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
228410008030	Walker A motif; other site
228410008031	ATP binding site [chemical binding]; other site
228410008032	Walker B motif; other site
228410008033	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
228410008034	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.603) with cleavage site probability 0.349 at residue 21
228410008035	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
228410008036	Ligand Binding Site [chemical binding]; other site
228410008037	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
228410008038	5 probable transmembrane helices predicted by TMHMM2.0
228410008039	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
228410008040	active site
228410008041	nucleophile elbow; other site
228410008042	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
228410008043	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
228410008044	AAA domain; Region: AAA_26; pfam13500
228410008045	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
228410008046	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410008047	S-adenosylmethionine binding site [chemical binding]; other site
228410008048	pimelyl-[acyl-carrier protein] methyl ester esterase; Region: bioH; TIGR01738
228410008049	TAP-like protein; Region: Abhydrolase_4; pfam08386
228410008050	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
228410008051	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
228410008052	substrate-cofactor binding pocket; other site
228410008053	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410008054	catalytic residue [active]
228410008055	biotin synthase; Region: bioB; TIGR00433
228410008056	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
228410008057	FeS/SAM binding site; other site
228410008058	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
228410008059	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
228410008060	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
228410008061	active site
228410008062	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
228410008063	AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The...; Region: Rieske_AIFL_N; cd03478
228410008064	[2Fe-2S] cluster binding site [ion binding]; other site
228410008065	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
228410008066	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410008067	Isochorismatase family; Region: Isochorismatase; pfam00857
228410008068	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
228410008069	catalytic triad [active]
228410008070	dimer interface [polypeptide binding]; other site
228410008071	conserved cis-peptide bond; other site
228410008072	Protein of unknown function, DUF488; Region: DUF488; pfam04343
228410008073	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
228410008074	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
228410008075	Virulence protein [General function prediction only]; Region: COG3943
228410008076	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
228410008077	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
228410008078	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
228410008079	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
228410008080	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
228410008081	DNA methylase; Region: N6_N4_Mtase; pfam01555
228410008082	DNA methylase; Region: N6_N4_Mtase; pfam01555
228410008083	AAA domain; Region: AAA_21; pfam13304
228410008084	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410008085	ABC transporter signature motif; other site
228410008086	Walker B; other site
228410008087	D-loop; other site
228410008088	H-loop/switch region; other site
228410008089	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
228410008090	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410008091	ATP binding site [chemical binding]; other site
228410008092	putative Mg++ binding site [ion binding]; other site
228410008093	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410008094	nucleotide binding region [chemical binding]; other site
228410008095	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
228410008096	ATP-binding site [chemical binding]; other site
228410008097	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
228410008098	AMIN domain; Region: AMIN; pfam11741
228410008099	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
228410008100	Secretin and TonB N terminus short domain; Region: STN; pfam07660
228410008101	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
228410008102	Tfp pilus assembly protein PilP [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilP; COG3168
228410008103	Pilus assembly protein, PilP; Region: PilP; pfam04351
228410008104	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.958) with cleavage site probability 0.297 at residue 22
228410008105	Pilus assembly protein, PilO; Region: PilO; pfam04350
228410008106	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
228410008107	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
228410008108	1 probable transmembrane helix predicted by TMHMM2.0
228410008109	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; pfam00370
228410008110	Competence protein A; Region: Competence_A; pfam11104
228410008111	Cell division protein FtsA; Region: FtsA; pfam14450
228410008112	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
228410008113	Transglycosylase; Region: Transgly; pfam00912
228410008114	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
228410008115	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.957 at residue 28
228410008116	1 probable transmembrane helix predicted by TMHMM2.0
228410008117	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
228410008118	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
228410008119	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
228410008120	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
228410008121	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.991 at residue 20
228410008122	beta-hexosaminidase; Provisional; Region: PRK05337
228410008123	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
228410008124	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
228410008125	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
228410008126	active site
228410008127	hydrophilic channel; other site
228410008128	dimerization interface [polypeptide binding]; other site
228410008129	catalytic residues [active]
228410008130	active site lid [active]
228410008131	GTPase Era; Reviewed; Region: era; PRK00089
228410008132	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
228410008133	G1 box; other site
228410008134	GTP/Mg2+ binding site [chemical binding]; other site
228410008135	Switch I region; other site
228410008136	G2 box; other site
228410008137	Switch II region; other site
228410008138	G3 box; other site
228410008139	G4 box; other site
228410008140	G5 box; other site
228410008141	KH domain; Region: KH_2; pfam07650
228410008142	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
228410008143	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
228410008144	dimerization interface [polypeptide binding]; other site
228410008145	active site
228410008146	metal binding site [ion binding]; metal-binding site
228410008147	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
228410008148	dsRNA binding site [nucleotide binding]; other site
228410008149	1 probable transmembrane helix predicted by TMHMM2.0
228410008150	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
228410008151	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
228410008152	Catalytic site [active]
228410008153	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
228410008154	2 probable transmembrane helices predicted by TMHMM2.0
228410008155	GTP-binding protein LepA; Provisional; Region: PRK05433
228410008156	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
228410008157	G1 box; other site
228410008158	putative GEF interaction site [polypeptide binding]; other site
228410008159	GTP/Mg2+ binding site [chemical binding]; other site
228410008160	Switch I region; other site
228410008161	G2 box; other site
228410008162	G3 box; other site
228410008163	Switch II region; other site
228410008164	G4 box; other site
228410008165	G5 box; other site
228410008166	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
228410008167	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
228410008168	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
228410008169	Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768
228410008170	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
228410008171	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
228410008172	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
228410008173	protein binding site [polypeptide binding]; other site
228410008174	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
228410008175	protein binding site [polypeptide binding]; other site
228410008176	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.998 at residue 52
228410008177	1 probable transmembrane helix predicted by TMHMM2.0
228410008178	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
228410008179	1 probable transmembrane helix predicted by TMHMM2.0
228410008180	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
228410008181	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410008182	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410008183	DNA binding residues [nucleotide binding]
228410008184	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
228410008185	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
228410008186	Transporter associated domain; Region: CorC_HlyC; smart01091
228410008187	Uncharacterized protein family UPF0054; Region: UPF0054; cl00402
228410008188	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
228410008189	PhoH-like protein; Region: PhoH; pfam02562
228410008190	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
228410008191	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
228410008192	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
228410008193	FeS/SAM binding site; other site
228410008194	TRAM domain; Region: TRAM; pfam01938
228410008195	NapC/NirT cytochrome c family, N-terminal region; Region: Cytochrom_NNT; pfam03264
228410008196	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
228410008197	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.690 at residue 29
228410008198	1 probable transmembrane helix predicted by TMHMM2.0
228410008199	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
228410008200	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 25
228410008201	1 probable transmembrane helix predicted by TMHMM2.0
228410008202	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
228410008203	Seven times multi-haem cytochrome CxxCH; Region: Multi-haem_cyto; pfam13447
228410008204	1 probable transmembrane helix predicted by TMHMM2.0
228410008205	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 at residue 25
228410008206	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
228410008207	acetyl-CoA synthetase; Provisional; Region: PRK00174
228410008208	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
228410008209	active site
228410008210	CoA binding site [chemical binding]; other site
228410008211	acyl-activating enzyme (AAE) consensus motif; other site
228410008212	AMP binding site [chemical binding]; other site
228410008213	acetate binding site [chemical binding]; other site
228410008214	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
228410008215	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
228410008216	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
228410008217	active site
228410008218	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 at residue 37
228410008219	1 probable transmembrane helix predicted by TMHMM2.0
228410008220	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
228410008221	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.875) with cleavage site probability 0.361 at residue 46
228410008222	1 probable transmembrane helix predicted by TMHMM2.0
228410008223	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
228410008224	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
228410008225	catalytic site [active]
228410008226	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
228410008227	putative substrate translocation pore; other site
228410008228	Major Facilitator Superfamily; Region: MFS_1; pfam07690
228410008229	12 probable transmembrane helices predicted by TMHMM2.0
228410008230	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
228410008231	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
228410008232	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
228410008233	active site
228410008234	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
228410008235	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
228410008236	acyl-activating enzyme (AAE) consensus motif; other site
228410008237	AMP binding site [chemical binding]; other site
228410008238	active site
228410008239	CoA binding site [chemical binding]; other site
228410008240	1 probable transmembrane helix predicted by TMHMM2.0
228410008241	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
228410008242	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
228410008243	CoA-transferase family III; Region: CoA_transf_3; pfam02515
228410008244	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
228410008245	MoaE interaction surface [polypeptide binding]; other site
228410008246	MoeB interaction surface [polypeptide binding]; other site
228410008247	thiocarboxylated glycine; other site
228410008248	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding); Region: MPN_like; cd08070
228410008249	MPN+ (JAMM) motif; other site
228410008250	Zinc-binding site [ion binding]; other site
228410008251	molybdopterin biosynthesis-like protein MoeZ; Validated; Region: PRK07878
228410008252	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
228410008253	ATP binding site [chemical binding]; other site
228410008254	substrate interface [chemical binding]; other site
228410008255	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
228410008256	active site residue [active]
228410008257	1 probable transmembrane helix predicted by TMHMM2.0
228410008258	1 probable transmembrane helix predicted by TMHMM2.0
228410008259	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
228410008260	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
228410008261	dimer interface [polypeptide binding]; other site
228410008262	putative anticodon binding site; other site
228410008263	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
228410008264	motif 1; other site
228410008265	active site
228410008266	motif 2; other site
228410008267	motif 3; other site
228410008268	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
228410008269	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
228410008270	active site
228410008271	HIGH motif; other site
228410008272	nucleotide binding site [chemical binding]; other site
228410008273	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
228410008274	KMSKS motif; other site
228410008275	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
228410008276	NlpC/P60 family; Region: NLPC_P60; pfam00877
228410008277	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.902) with cleavage site probability 0.531 at residue 25
228410008278	PEP synthetase regulatory protein; Provisional; Region: PRK05339
228410008279	phosphoenolpyruvate synthase; Validated; Region: PRK06464
228410008280	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
228410008281	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
228410008282	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
228410008283	Xcc1710_like family, specific to proteobacteria. Xcc1710 is a hypothetical protein from Xanthomonas campestris pv. campestris str. ATCC 33913, similar to Mth938, a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome; Region: Xcc1710_like; cd05560
228410008284	5' remnant of a gene destroyed by the creation of a 7.5kb repeat, the intact gene is NE2355;OB-fold nucleic acid binding domain
228410008285	5' remnant of gene destroyed by the creation of a 7.5 kb repeat, the intact gene is NE2368;probable aminotransferase
228410008286	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
228410008287	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
228410008288	active site
228410008289	HIGH motif; other site
228410008290	nucleotide binding site [chemical binding]; other site
228410008291	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
228410008292	KMSKS motif; other site
228410008293	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
228410008294	NlpC/P60 family; Region: NLPC_P60; pfam00877
228410008295	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.902) with cleavage site probability 0.531 at residue 25
228410008296	PEP synthetase regulatory protein; Provisional; Region: PRK05339
228410008297	phosphoenolpyruvate synthase; Validated; Region: PRK06464
228410008298	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
228410008299	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
228410008300	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
228410008301	Xcc1710_like family, specific to proteobacteria. Xcc1710 is a hypothetical protein from Xanthomonas campestris pv. campestris str. ATCC 33913, similar to Mth938, a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome; Region: Xcc1710_like; cd05560
228410008302	aminotransferase AlaT; Validated; Region: PRK09265
228410008303	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
228410008304	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410008305	homodimer interface [polypeptide binding]; other site
228410008306	catalytic residue [active]
228410008307	homoserine dehydrogenase; Provisional; Region: PRK06349
228410008308	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
228410008309	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
228410008310	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
228410008311	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
228410008312	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
228410008313	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410008314	catalytic residue [active]
228410008315	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
228410008316	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
228410008317	Flavinator of succinate dehydrogenase; Region: Sdh5; cl01110
228410008318	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
228410008319	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
228410008320	dimer interface [polypeptide binding]; other site
228410008321	active site
228410008322	citrylCoA binding site [chemical binding]; other site
228410008323	NADH binding [chemical binding]; other site
228410008324	cationic pore residues; other site
228410008325	oxalacetate/citrate binding site [chemical binding]; other site
228410008326	coenzyme A binding site [chemical binding]; other site
228410008327	catalytic triad [active]
228410008328	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
228410008329	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
228410008330	TPP-binding site [chemical binding]; other site
228410008331	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
228410008332	dimer interface [polypeptide binding]; other site
228410008333	PYR/PP interface [polypeptide binding]; other site
228410008334	TPP binding site [chemical binding]; other site
228410008335	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
228410008336	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
228410008337	E3 interaction surface; other site
228410008338	lipoyl attachment site [posttranslational modification]; other site
228410008339	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
228410008340	BolA-like protein; Region: BolA; pfam01722
228410008341	ABC-2 type transporter; Region: ABC2_membrane; cl17235
228410008342	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
228410008343	7 probable transmembrane helices predicted by TMHMM2.0
228410008344	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.884) with cleavage site probability 0.686 at residue 43
228410008345	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
228410008346	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
228410008347	Walker A/P-loop; other site
228410008348	ATP binding site [chemical binding]; other site
228410008349	Q-loop/lid; other site
228410008350	ABC transporter signature motif; other site
228410008351	Walker B; other site
228410008352	D-loop; other site
228410008353	H-loop/switch region; other site
228410008354	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
228410008355	anti sigma factor interaction site; other site
228410008356	regulatory phosphorylation site [posttranslational modification]; other site
228410008357	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494
228410008358	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.854 at residue 23
228410008359	1 probable transmembrane helix predicted by TMHMM2.0
228410008360	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
228410008361	mce related protein; Region: MCE; pfam02470
228410008362	1 probable transmembrane helix predicted by TMHMM2.0
228410008363	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
228410008364	Permease; Region: Permease; pfam02405
228410008365	6 probable transmembrane helices predicted by TMHMM2.0
228410008366	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
228410008367	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
228410008368	Walker A/P-loop; other site
228410008369	ATP binding site [chemical binding]; other site
228410008370	Q-loop/lid; other site
228410008371	ABC transporter signature motif; other site
228410008372	Walker B; other site
228410008373	D-loop; other site
228410008374	H-loop/switch region; other site
228410008375	Domain of unknown function (DUF4124); Region: DUF4124; pfam13511
228410008376	Staphylococcal nuclease homologues; Region: SNc; smart00318
228410008377	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
228410008378	Catalytic site; other site
228410008379	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.947 at residue 38
228410008380	1 probable transmembrane helix predicted by TMHMM2.0
228410008381	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
228410008382	Bacterial SH3 domain; Region: SH3_3; cl17532
228410008383	2 probable transmembrane helices predicted by TMHMM2.0
228410008384	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.634 at residue 27
228410008385	2 probable transmembrane helices predicted by TMHMM2.0
228410008386	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
228410008387	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
228410008388	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
228410008389	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
228410008390	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
228410008391	DsbD alpha interface [polypeptide binding]; other site
228410008392	catalytic residues [active]
228410008393	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 21
228410008394	8 probable transmembrane helices predicted by TMHMM2.0
228410008395	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
228410008396	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
228410008397	catalytic residues [active]
228410008398	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.415 at residue 20
228410008399	1 probable transmembrane helix predicted by TMHMM2.0
228410008400	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
228410008401	ApbE family; Region: ApbE; pfam02424
228410008402	Protein of unknown function (DUF539); Region: DUF539; cl01129
228410008403	2 probable transmembrane helices predicted by TMHMM2.0
228410008404	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.569 at residue 34
228410008405	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
228410008406	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
228410008407	catalytic loop [active]
228410008408	iron binding site [ion binding]; other site
228410008409	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
228410008410	FAD binding pocket [chemical binding]; other site
228410008411	FAD binding motif [chemical binding]; other site
228410008412	phosphate binding motif [ion binding]; other site
228410008413	beta-alpha-beta structure motif; other site
228410008414	NAD binding pocket [chemical binding]; other site
228410008415	1 probable transmembrane helix predicted by TMHMM2.0
228410008416	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
228410008417	6 probable transmembrane helices predicted by TMHMM2.0
228410008418	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
228410008419	5 probable transmembrane helices predicted by TMHMM2.0
228410008420	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
228410008421	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
228410008422	1 probable transmembrane helix predicted by TMHMM2.0
228410008423	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.912) with cleavage site probability 0.405 at residue 35
228410008424	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
228410008425	8 probable transmembrane helices predicted by TMHMM2.0
228410008426	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
228410008427	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
228410008428	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623
228410008429	FOG: CBS domain [General function prediction only]; Region: COG0517
228410008430	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
228410008431	HSP70 interaction site [polypeptide binding]; other site
228410008432	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
228410008433	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
228410008434	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410008435	homodimer interface [polypeptide binding]; other site
228410008436	catalytic residue [active]
228410008437	5-histidylcysteine sulfoxide synthase; Region: ovoA_Nterm; TIGR04344
228410008438	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
228410008439	Methyltransferase domain; Region: Methyltransf_31; pfam13847
228410008440	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410008441	S-adenosylmethionine binding site [chemical binding]; other site
228410008442	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
228410008443	Clp amino terminal domain; Region: Clp_N; pfam02861
228410008444	Clp amino terminal domain; Region: Clp_N; pfam02861
228410008445	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410008446	Walker A motif; other site
228410008447	ATP binding site [chemical binding]; other site
228410008448	Walker B motif; other site
228410008449	arginine finger; other site
228410008450	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410008451	Walker A motif; other site
228410008452	ATP binding site [chemical binding]; other site
228410008453	Walker B motif; other site
228410008454	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
228410008455	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
228410008456	dihydrodipicolinate synthase; Region: dapA; TIGR00674
228410008457	dimer interface [polypeptide binding]; other site
228410008458	active site
228410008459	catalytic residue [active]
228410008460	Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane]; Region: NlpB; COG3317
228410008461	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
228410008462	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.877) with cleavage site probability 0.667 at residue 18
228410008463	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
228410008464	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
228410008465	13 probable transmembrane helices predicted by TMHMM2.0
228410008466	transcriptional activator FlhC; Provisional; Region: PRK12722
228410008467	transcriptional activator FlhD; Provisional; Region: PRK02909
228410008468	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
228410008469	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
228410008470	Competence protein; Region: Competence; pfam03772
228410008471	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
228410008472	10 probable transmembrane helices predicted by TMHMM2.0
228410008473	Protein of unknown function (DUF466); Region: DUF466; pfam04328
228410008474	carbon starvation protein A; Provisional; Region: PRK15015
228410008475	Carbon starvation protein CstA; Region: CstA; pfam02554
228410008476	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
228410008477	16 probable transmembrane helices predicted by TMHMM2.0
228410008478	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.987) with cleavage site probability 0.501 at residue 26
228410008479	ISNE2
228410008480	Winged helix-turn helix; Region: HTH_29; pfam13551
228410008481	Integrase core domain; Region: rve; pfam00665
228410008482	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410008483	Integrase core domain; Region: rve_3; pfam13683
228410008484	ISNE4
228410008485	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410008486	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410008487	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410008488	ISNE1
228410008489	Winged helix-turn helix; Region: HTH_29; pfam13551
228410008490	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410008491	Homeodomain-like domain; Region: HTH_32; pfam13565
228410008492	Integrase core domain; Region: rve; pfam00665
228410008493	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410008494	Integrase core domain; Region: rve_3; pfam13683
228410008495	3' remnant of gene interrupted by an IS element;Probable Sensory transduction histidine kinases
228410008496	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
228410008497	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
228410008498	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
228410008499	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
228410008500	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
228410008501	carboxyltransferase (CT) interaction site; other site
228410008502	biotinylation site [posttranslational modification]; other site
228410008503	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
228410008504	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
228410008505	urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425
228410008506	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
228410008507	permease, urea carboxylase system; Region: ureacarb_perm; TIGR03428
228410008508	12 probable transmembrane helices predicted by TMHMM2.0
228410008509	urea carboxylase; Region: urea_carbox; TIGR02712
228410008510	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
228410008511	ATP-grasp domain; Region: ATP-grasp_4; cl17255
228410008512	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
228410008513	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
228410008514	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
228410008515	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
228410008516	carboxyltransferase (CT) interaction site; other site
228410008517	biotinylation site [posttranslational modification]; other site
228410008518	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
228410008519	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
228410008520	N-acetyl-D-glucosamine binding site [chemical binding]; other site
228410008521	catalytic residue [active]
228410008522	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
228410008523	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
228410008524	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
228410008525	1 probable transmembrane helix predicted by TMHMM2.0
228410008526	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.906 at residue 27
228410008527	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
228410008528	dimer interface [polypeptide binding]; other site
228410008529	putative radical transfer pathway; other site
228410008530	diiron center [ion binding]; other site
228410008531	tyrosyl radical; other site
228410008532	1 probable transmembrane helix predicted by TMHMM2.0
228410008533	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07207
228410008534	ATP cone domain; Region: ATP-cone; pfam03477
228410008535	ATP cone domain; Region: ATP-cone; pfam03477
228410008536	Class I ribonucleotide reductase; Region: RNR_I; cd01679
228410008537	active site
228410008538	dimer interface [polypeptide binding]; other site
228410008539	catalytic residues [active]
228410008540	effector binding site; other site
228410008541	R2 peptide binding site; other site
228410008542	NE2424 and NE2425 are 2 parts of a pseudogene caused by a frameshift
228410008543	NE2424 and NE2425 are dead genes due to a frameshift;Phospholipid and glycerol acyltransferase (from motifs_6.msf)
228410008544	12 probable transmembrane helices predicted by TMHMM2.0
228410008545	NE2424 and NE2425 are dead genes due to a frameshift; 2-acylglycerophosphoethanolamine acyltransferase
228410008546	Methyltransferase domain; Region: Methyltransf_23; pfam13489
228410008547	Methyltransferase domain; Region: Methyltransf_12; pfam08242
228410008548	1 probable transmembrane helix predicted by TMHMM2.0
228410008549	1 probable transmembrane helix predicted by TMHMM2.0
228410008550	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
228410008551	putative active site [active]
228410008552	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
228410008553	4 probable transmembrane helices predicted by TMHMM2.0
228410008554	Secretin and TonB N terminus short domain; Region: STN; smart00965
228410008555	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410008556	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410008557	N-terminal plug; other site
228410008558	ligand-binding site [chemical binding]; other site
228410008559	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.967) with cleavage site probability 0.864 at residue 45
228410008560	fec operon regulator FecR; Reviewed; Region: PRK09774
228410008561	FecR protein; Region: FecR; pfam04773
228410008562	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410008563	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410008564	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410008565	DNA binding residues [nucleotide binding]
228410008566	EcsC protein family; Region: EcsC; pfam12787
228410008567	2 probable transmembrane helices predicted by TMHMM2.0
228410008568	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
228410008569	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; cl15433
228410008570	1 probable transmembrane helix predicted by TMHMM2.0
228410008571	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
228410008572	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
228410008573	Ligand binding site; other site
228410008574	DXD motif; other site
228410008575	6 probable transmembrane helices predicted by TMHMM2.0
228410008576	CsbD-like; Region: CsbD; cl17424
228410008577	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.930 at residue 33
228410008578	1 probable transmembrane helix predicted by TMHMM2.0
228410008579	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.805 at residue 25
228410008580	ISNE1
228410008581	Winged helix-turn helix; Region: HTH_29; pfam13551
228410008582	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410008583	Homeodomain-like domain; Region: HTH_32; pfam13565
228410008584	Integrase core domain; Region: rve; pfam00665
228410008585	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410008586	Integrase core domain; Region: rve_3; pfam13683
228410008587	Protein of unknown function (DUF3465); Region: DUF3465; pfam11948
228410008588	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.887) with cleavage site probability 0.684 at residue 19
228410008589	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
228410008590	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.940 at residue 42
228410008591	ISNE1
228410008592	Winged helix-turn helix; Region: HTH_29; pfam13551
228410008593	Helix-turn-helix domain; Region: HTH_28; pfam13518
228410008594	Homeodomain-like domain; Region: HTH_32; pfam13565
228410008595	Integrase core domain; Region: rve; pfam00665
228410008596	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
228410008597	Integrase core domain; Region: rve_3; pfam13683
228410008598	ISNE4
228410008599	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410008600	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
228410008601	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
228410008602	5' remnant of gene interrupted by an IS element;possible type I restriction-modification enzyme R subunit
228410008603	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.944) with cleavage site probability 0.939 at residue 33
228410008604	1 probable transmembrane helix predicted by TMHMM2.0
228410008605	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
228410008606	Mrr N-terminal domain; Region: Mrr_N; pfam14338
228410008607	Restriction endonuclease; Region: Mrr_cat; pfam04471
228410008608	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
228410008609	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
228410008610	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
228410008611	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410008612	Walker A/P-loop; other site
228410008613	ATP binding site [chemical binding]; other site
228410008614	Q-loop/lid; other site
228410008615	ABC transporter signature motif; other site
228410008616	Walker B; other site
228410008617	D-loop; other site
228410008618	H-loop/switch region; other site
228410008619	5 probable transmembrane helices predicted by TMHMM2.0
228410008620	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
228410008621	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
228410008622	dimer interface [polypeptide binding]; other site
228410008623	ssDNA binding site [nucleotide binding]; other site
228410008624	tetramer (dimer of dimers) interface [polypeptide binding]; other site
228410008625	Major Facilitator Superfamily; Region: MFS_1; pfam07690
228410008626	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
228410008627	putative substrate translocation pore; other site
228410008628	12 probable transmembrane helices predicted by TMHMM2.0
228410008629	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.770) with cleavage site probability 0.760 at residue 35
228410008630	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
228410008631	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
228410008632	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
228410008633	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
228410008634	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
228410008635	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
228410008636	MOFRL family; Region: MOFRL; pfam05161
228410008637	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
228410008638	dimer interface [polypeptide binding]; other site
228410008639	active site
228410008640	aspartate-rich active site metal binding site; other site
228410008641	allosteric magnesium binding site [ion binding]; other site
228410008642	Schiff base residues; other site
228410008643	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
228410008644	G1 box; other site
228410008645	GTP/Mg2+ binding site [chemical binding]; other site
228410008646	Switch I region; other site
228410008647	G2 box; other site
228410008648	G3 box; other site
228410008649	Switch II region; other site
228410008650	G4 box; other site
228410008651	G5 box; other site
228410008652	pantothenate kinase; Reviewed; Region: PRK13329
228410008653	HTH domain; Region: HTH_11; pfam08279
228410008654	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
228410008655	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
228410008656	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
228410008657	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.825 at residue 25
228410008658	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
228410008659	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
228410008660	trimer interface [polypeptide binding]; other site
228410008661	active site
228410008662	substrate binding site [chemical binding]; other site
228410008663	CoA binding site [chemical binding]; other site
228410008664	succinyldiaminopimelate transaminase; Provisional; Region: PRK09147
228410008665	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
228410008666	pyridoxal 5'-phosphate binding site [chemical binding]; other site
228410008667	homodimer interface [polypeptide binding]; other site
228410008668	catalytic residue [active]
228410008669	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
228410008670	EamA-like transporter family; Region: EamA; cl17759
228410008671	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.974) with cleavage site probability 0.762 at residue 22
228410008672	10 probable transmembrane helices predicted by TMHMM2.0
228410008673	peroxiredoxin; Region: AhpC; TIGR03137
228410008674	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
228410008675	dimer interface [polypeptide binding]; other site
228410008676	decamer (pentamer of dimers) interface [polypeptide binding]; other site
228410008677	catalytic triad [active]
228410008678	peroxidatic and resolving cysteines [active]
228410008679	CNP1-like family; Region: CNP1; pfam08750
228410008680	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.747) with cleavage site probability 0.563 at residue 26
228410008681	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
228410008682	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
228410008683	1 probable transmembrane helix predicted by TMHMM2.0
228410008684	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.608) with cleavage site probability 0.383 at residue 22
228410008685	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_1; cd07020
228410008686	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
228410008687	active site residues [active]
228410008688	dimer interface [polypeptide binding]; other site
228410008689	NfeD-like C-terminal, partner-binding; Region: NfeD; pfam01957
228410008690	5 probable transmembrane helices predicted by TMHMM2.0
228410008691	ISNE6
228410008692	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
228410008693	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410008694	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
228410008695	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
228410008696	dimer interface [polypeptide binding]; other site
228410008697	ADP-ribose binding site [chemical binding]; other site
228410008698	active site
228410008699	nudix motif; other site
228410008700	metal binding site [ion binding]; metal-binding site
228410008701	Tim44-like domain; Region: Tim44; pfam04280
228410008702	2 probable transmembrane helices predicted by TMHMM2.0
228410008703	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.955) with cleavage site probability 0.604 at residue 16
228410008704	hypothetical protein; Provisional; Region: PRK11820
228410008705	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
228410008706	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
228410008707	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
228410008708	ParB-like nuclease domain; Region: ParBc; pfam02195
228410008709	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
228410008710	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
228410008711	P-loop; other site
228410008712	Magnesium ion binding site [ion binding]; other site
228410008713	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
228410008714	Magnesium ion binding site [ion binding]; other site
228410008715	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
228410008716	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410008717	S-adenosylmethionine binding site [chemical binding]; other site
228410008718	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
228410008719	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
228410008720	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
228410008721	FlgN protein; Region: FlgN; pfam05130
228410008722	flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824
228410008723	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
228410008724	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
228410008725	dimer interface [polypeptide binding]; other site
228410008726	conserved gate region; other site
228410008727	putative PBP binding loops; other site
228410008728	ABC-ATPase subunit interface; other site
228410008729	9 probable transmembrane helices predicted by TMHMM2.0
228410008730	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
228410008731	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
228410008732	Walker A/P-loop; other site
228410008733	ATP binding site [chemical binding]; other site
228410008734	Q-loop/lid; other site
228410008735	ABC transporter signature motif; other site
228410008736	Walker B; other site
228410008737	D-loop; other site
228410008738	H-loop/switch region; other site
228410008739	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
228410008740	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
228410008741	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
228410008742	Walker A/P-loop; other site
228410008743	ATP binding site [chemical binding]; other site
228410008744	Q-loop/lid; other site
228410008745	ABC transporter signature motif; other site
228410008746	Walker B; other site
228410008747	D-loop; other site
228410008748	H-loop/switch region; other site
228410008749	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
228410008750	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
228410008751	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
228410008752	G1 box; other site
228410008753	putative GEF interaction site [polypeptide binding]; other site
228410008754	GTP/Mg2+ binding site [chemical binding]; other site
228410008755	Switch I region; other site
228410008756	G2 box; other site
228410008757	G3 box; other site
228410008758	Switch II region; other site
228410008759	G4 box; other site
228410008760	G5 box; other site
228410008761	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
228410008762	NE2482 and NE2484 are 2 parts of a dead gene due to IS element insertion;TonB-dependent receptor protein
228410008763	Winged helix-turn helix; Region: HTH_29; pfam13551
228410008764	Integrase core domain; Region: rve; pfam00665
228410008765	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410008766	Integrase core domain; Region: rve_3; pfam13683
228410008767	ISNE2
228410008768	NE2482 and NE2484 are 2 parts of a dead gene due to IS element insertion;possible TonB-dependent receptor
228410008769	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.847) with cleavage site probability 0.655 at residue 52
228410008770	fec operon regulator FecR; Reviewed; Region: PRK09774
228410008771	FecR protein; Region: FecR; pfam04773
228410008772	RNA polymerase sigma factor; Provisional; Region: PRK12528
228410008773	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410008774	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410008775	DNA binding residues [nucleotide binding]
228410008776	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
228410008777	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
228410008778	4 probable transmembrane helices predicted by TMHMM2.0
228410008779	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
228410008780	FHIPEP family; Region: FHIPEP; pfam00771
228410008781	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.678) with cleavage site probability 0.590 at residue 21
228410008782	7 probable transmembrane helices predicted by TMHMM2.0
228410008783	flagellar biosynthesis regulator FlhF; Provisional; Region: flhF; PRK14721
228410008784	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
228410008785	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
228410008786	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
228410008787	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
228410008788	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
228410008789	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
228410008790	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
228410008791	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
228410008792	DNA binding residues [nucleotide binding]
228410008793	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
228410008794	Major Facilitator Superfamily; Region: MFS_1; pfam07690
228410008795	putative substrate translocation pore; other site
228410008796	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
228410008797	10 probable transmembrane helices predicted by TMHMM2.0
228410008798	Predicted membrane protein [Function unknown]; Region: COG2119
228410008799	Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169
228410008800	Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169
228410008801	5 probable transmembrane helices predicted by TMHMM2.0
228410008802	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
228410008803	AAA domain; Region: AAA_21; pfam13304
228410008804	Walker A/P-loop; other site
228410008805	ATP binding site [chemical binding]; other site
228410008806	AAA domain; Region: AAA_21; pfam13304
228410008807	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
228410008808	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
228410008809	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
228410008810	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
228410008811	HsdM N-terminal domain; Region: HsdM_N; pfam12161
228410008812	Methyltransferase domain; Region: Methyltransf_26; pfam13659
228410008813	KilA-N domain; Region: KilA-N; pfam04383
228410008814	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
228410008815	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
228410008816	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410008817	ATP binding site [chemical binding]; other site
228410008818	putative Mg++ binding site [ion binding]; other site
228410008819	Predicted membrane protein (DUF2231); Region: DUF2231; cl01730
228410008820	4 probable transmembrane helices predicted by TMHMM2.0
228410008821	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
228410008822	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.817) with cleavage site probability 0.200 at residue 21
228410008823	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
228410008824	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.975 at residue 29
228410008825	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
228410008826	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
228410008827	N-terminal plug; other site
228410008828	ligand-binding site [chemical binding]; other site
228410008829	ISNE6
228410008830	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
228410008831	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
228410008832	Fic family protein [Function unknown]; Region: COG3177
228410008833	Domain of unknown function (DUF4172); Region: DUF4172; pfam13776
228410008834	Fic/DOC family; Region: Fic; pfam02661
228410008835	Helix-turn-helix domain; Region: HTH_17; pfam12728
228410008836	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
228410008837	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
228410008838	conserved cys residue [active]
228410008839	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
228410008840	Domain of unknown function (DUF336); Region: DUF336; cl01249
228410008841	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 at residue 23
228410008842	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
228410008843	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
228410008844	FMN binding site [chemical binding]; other site
228410008845	active site
228410008846	substrate binding site [chemical binding]; other site
228410008847	catalytic residue [active]
228410008848	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
228410008849	conserved cys residue [active]
228410008850	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
228410008851	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
228410008852	Protein of unknown function (DUF3223); Region: DUF3223; pfam11523
228410008853	Predicted transcriptional regulator [Transcription]; Region: COG2378
228410008854	WYL domain; Region: WYL; pfam13280
228410008855	ISNE3
228410008856	putative transposase OrfB; Reviewed; Region: PHA02517
228410008857	HTH-like domain; Region: HTH_21; pfam13276
228410008858	Integrase core domain; Region: rve; pfam00665
228410008859	Integrase core domain; Region: rve_3; pfam13683
228410008860	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
228410008861	active site
228410008862	NTP binding site [chemical binding]; other site
228410008863	metal binding triad [ion binding]; metal-binding site
228410008864	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
228410008865	active site
228410008866	nucleophile elbow; other site
228410008867	Predicted transcriptional regulator [Transcription]; Region: COG2378
228410008868	WYL domain; Region: WYL; pfam13280
228410008869	DEAD-like helicases superfamily; Region: DEXDc; smart00487
228410008870	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410008871	ATP binding site [chemical binding]; other site
228410008872	putative Mg++ binding site [ion binding]; other site
228410008873	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410008874	nucleotide binding region [chemical binding]; other site
228410008875	ATP-binding site [chemical binding]; other site
228410008876	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
228410008877	active site
228410008878	DNA protecting protein DprA; Region: dprA; TIGR00732
228410008879	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
228410008880	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.912) with cleavage site probability 0.481 at residue 29
228410008881	HsdM N-terminal domain; Region: HsdM_N; pfam12161
228410008882	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
228410008883	Methyltransferase domain; Region: Methyltransf_26; pfam13659
228410008884	1 probable transmembrane helix predicted by TMHMM2.0
228410008885	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
228410008886	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
228410008887	HsdM N-terminal domain; Region: HsdM_N; pfam12161
228410008888	Methyltransferase domain; Region: Methyltransf_26; pfam13659
228410008889	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
228410008890	Divergent AAA domain; Region: AAA_4; pfam04326
228410008891	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
228410008892	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
228410008893	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
228410008894	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
228410008895	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
228410008896	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
228410008897	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410008898	ATP binding site [chemical binding]; other site
228410008899	putative Mg++ binding site [ion binding]; other site
228410008900	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
228410008901	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
228410008902	Walker A motif; other site
228410008903	ATP binding site [chemical binding]; other site
228410008904	Walker B motif; other site
228410008905	arginine finger; other site
228410008906	5-methylcytosine-specific restriction enzyme subunit McrC; Provisional; Region: PRK09736
228410008907	ISNE3
228410008908	putative transposase OrfB; Reviewed; Region: PHA02517
228410008909	HTH-like domain; Region: HTH_21; pfam13276
228410008910	Integrase core domain; Region: rve; pfam00665
228410008911	Integrase core domain; Region: rve_3; pfam13683
228410008912	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
228410008913	catalytic residues [active]
228410008914	ISNE2
228410008915	Winged helix-turn helix; Region: HTH_29; pfam13551
228410008916	Integrase core domain; Region: rve; pfam00665
228410008917	DDE domain; Region: DDE_Tnp_IS240; pfam13610
228410008918	Integrase core domain; Region: rve_3; pfam13683
228410008919	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
228410008920	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
228410008921	non-specific DNA binding site [nucleotide binding]; other site
228410008922	salt bridge; other site
228410008923	sequence-specific DNA binding site [nucleotide binding]; other site
228410008924	Domain of unknown function (DUF955); Region: DUF955; pfam06114
228410008925	Protein of unknown function (DUF2924); Region: DUF2924; pfam11149
228410008926	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
228410008927	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
228410008928	catalytic residues [active]
228410008929	catalytic nucleophile [active]
228410008930	Presynaptic Site I dimer interface [polypeptide binding]; other site
228410008931	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
228410008932	Synaptic Flat tetramer interface [polypeptide binding]; other site
228410008933	Synaptic Site I dimer interface [polypeptide binding]; other site
228410008934	DNA binding site [nucleotide binding]
228410008935	Recombinase; Region: Recombinase; pfam07508
228410008936	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
228410008937	TIGR04255 family protein; Region: sporadTIGR04255
228410008938	phosphoglycolate phosphatase; Provisional; Region: PRK13222
228410008939	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
228410008940	motif II; other site
228410008941	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
228410008942	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
228410008943	S-adenosylmethionine binding site [chemical binding]; other site
228410008944	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
228410008945	ligand binding site [chemical binding]; other site
228410008946	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.948 at residue 29
228410008947	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
228410008948	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
228410008949	Walker A/P-loop; other site
228410008950	ATP binding site [chemical binding]; other site
228410008951	Q-loop/lid; other site
228410008952	ABC transporter signature motif; other site
228410008953	Walker B; other site
228410008954	D-loop; other site
228410008955	H-loop/switch region; other site
228410008956	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
228410008957	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.791) with cleavage site probability 0.733 at residue 33
228410008958	6 probable transmembrane helices predicted by TMHMM2.0
228410008959	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
228410008960	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.978) with cleavage site probability 0.798 at residue 35
228410008961	2 probable transmembrane helices predicted by TMHMM2.0
228410008962	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
228410008963	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
228410008964	DNA binding site [nucleotide binding]
228410008965	catalytic residue [active]
228410008966	H2TH interface [polypeptide binding]; other site
228410008967	putative catalytic residues [active]
228410008968	turnover-facilitating residue; other site
228410008969	intercalation triad [nucleotide binding]; other site
228410008970	8OG recognition residue [nucleotide binding]; other site
228410008971	putative reading head residues; other site
228410008972	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
228410008973	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
228410008974	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
228410008975	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
228410008976	catalytic residues [active]
228410008977	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
228410008978	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
228410008979	G1 box; other site
228410008980	putative GEF interaction site [polypeptide binding]; other site
228410008981	GTP/Mg2+ binding site [chemical binding]; other site
228410008982	Switch I region; other site
228410008983	G2 box; other site
228410008984	G3 box; other site
228410008985	Switch II region; other site
228410008986	G4 box; other site
228410008987	G5 box; other site
228410008988	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
228410008989	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
228410008990	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
228410008991	Lumazine binding domain; Region: Lum_binding; pfam00677
228410008992	Lumazine binding domain; Region: Lum_binding; pfam00677
228410008993	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Provisional; Region: PRK14019
228410008994	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
228410008995	GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925
228410008996	dimerization interface [polypeptide binding]; other site
228410008997	active site
228410008998	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
228410008999	homopentamer interface [polypeptide binding]; other site
228410009000	active site
228410009001	transcription antitermination factor NusB; Region: nusB; TIGR01951
228410009002	putative RNA binding site [nucleotide binding]; other site
228410009003	thiamine monophosphate kinase; Provisional; Region: PRK05731
228410009004	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
228410009005	ATP binding site [chemical binding]; other site
228410009006	dimerization interface [polypeptide binding]; other site
228410009007	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
228410009008	tetramer interfaces [polypeptide binding]; other site
228410009009	binuclear metal-binding site [ion binding]; other site
228410009010	4 probable transmembrane helices predicted by TMHMM2.0
228410009011	Competence-damaged protein; Region: CinA; cl00666
228410009012	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.941 at residue 23
228410009013	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
228410009014	trimer interface [polypeptide binding]; other site
228410009015	eyelet of channel; other site
228410009016	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
228410009017	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.822 at residue 23
228410009018	ATP-dependent DNA helicase, RecQ family; Region: recQ_fam; TIGR00614
228410009019	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
228410009020	ATP binding site [chemical binding]; other site
228410009021	putative Mg++ binding site [ion binding]; other site
228410009022	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
228410009023	nucleotide binding region [chemical binding]; other site
228410009024	ATP-binding site [chemical binding]; other site
228410009025	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
228410009026	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
228410009027	RNA binding surface [nucleotide binding]; other site
228410009028	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
228410009029	8 probable transmembrane helices predicted by TMHMM2.0
228410009030	Putative phosphatase (DUF442); Region: DUF442; cl17385
228410009031	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
228410009032	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
228410009033	dimerization interface [polypeptide binding]; other site
228410009034	putative DNA binding site [nucleotide binding]; other site
228410009035	putative Zn2+ binding site [ion binding]; other site
228410009036	Predicted transporter component [General function prediction only]; Region: COG2391
228410009037	Sulphur transport; Region: Sulf_transp; pfam04143
228410009038	4 probable transmembrane helices predicted by TMHMM2.0
228410009039	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.958) with cleavage site probability 0.715 at residue 25
228410009040	Predicted transporter component [General function prediction only]; Region: COG2391
228410009041	4 probable transmembrane helices predicted by TMHMM2.0
228410009042	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
228410009043	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
228410009044	Peptidase M15; Region: Peptidase_M15_3; cl01194
228410009045	Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.970) with cleavage site probability 0.889 at residue 42
228410009046	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
228410009047	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
228410009048	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
228410009049	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734