-- dump date   	20140619_165732
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_495284.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_495286.1	Modulates the activities of several enzymes which are inactive in their acetylated form
YP_495287.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_495292.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_495302.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_495304.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
YP_495306.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_495307.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_495312.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_495313.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_495318.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth
YP_495326.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_495342.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_495343.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_495351.1	catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA
YP_495356.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_495368.1	in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane
YP_495372.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_495377.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
YP_495389.1	involved in de novo purine biosynthesis
YP_495397.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_495401.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_495403.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_495419.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_495420.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_495424.1	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_495425.1	unwinds double stranded DNA
YP_495429.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_495441.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
YP_495444.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_495454.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_495455.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_495476.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_495478.1	with SufCD activates cysteine desulfurase SufS
YP_495486.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_495504.1	required for 70S ribosome assembly
YP_495553.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
YP_495556.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_495566.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_495570.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_495571.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_495579.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_495587.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_495594.1	type IV secretion VirB6 family
YP_495597.1	type IV secretion system VirB4 family
YP_495602.1	type IV secretion VirD4 coupling protein family
YP_495605.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
YP_495613.1	catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide
YP_495614.1	catalyzes the formation of precorrin 6x from precorrin 5
YP_495615.1	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
YP_495619.1	CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6
YP_495622.1	catalyzes the interconversion of precorrin-8X and hydrogenobyrinate
YP_495624.1	with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism
YP_495675.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_495699.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_495704.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_495705.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_495731.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_495746.1	associated with various cellular activities
YP_495749.1	catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
YP_495763.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_495770.1	in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media
YP_495784.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_495821.1	catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol
YP_495824.1	catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P
YP_495827.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_495831.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_495859.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_495860.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_495862.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_495869.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_495877.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_495886.1	catalyzes the hydrolysis of allophanate
YP_495956.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_495961.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_495963.1	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein
YP_495965.1	catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis
YP_495967.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_495969.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_495970.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_495976.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_495977.1	dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate
YP_495985.1	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain
YP_495998.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_495999.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
YP_496007.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_496038.1	catalyzes the interconversion of D-xylose to D-xylulose
YP_496071.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_496088.1	catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA
YP_496090.1	MDM; functions in conversion of succinate to propionate
YP_496092.1	catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
YP_496100.1	activates fatty acids by binding to coenzyme A
YP_496103.1	Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis
YP_496105.1	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys
YP_496112.1	binds directly to 23S ribosomal RNA
YP_496113.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_496125.1	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit
YP_496129.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_496142.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_496159.1	homopentamer; channel that opens in response to pressure or hypoosmotic shock
YP_496161.1	catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation
YP_496164.1	catalyzes the formation of malate from glyoxylate and acetyl-CoA
YP_496165.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_496169.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_496173.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_496178.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_496185.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_496189.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_496190.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
YP_496191.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_496194.1	converts protoheme IX and farnesyl diphosphate to heme O
YP_496196.1	involved in the insertion of copper into subunit I of cytochrome C oxidase
YP_496200.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_496209.1	involved in the peptidyltransferase reaction during translation
YP_496214.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_496218.1	a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH
YP_496229.2	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_496230.1	UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin
YP_496246.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_496249.1	NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_496250.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_496261.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_496282.1	Essential for recycling GMP and indirectly, cGMP
YP_496285.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
YP_496286.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_496288.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_496289.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_496290.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
YP_496296.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_496308.1	Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates
YP_496320.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_496328.1	transports L-rhamnose and L-lyxose into the cell
YP_496329.1	flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration
YP_496337.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_496339.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_496346.1	pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient
YP_496348.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_496350.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_496364.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_496368.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_496379.1	catalyzes the formation of 2-oxobutanoate from L-threonine
YP_496380.1	Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate
YP_496393.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis
YP_496400.1	CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis
YP_496407.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_496409.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_496412.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_496413.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_496414.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_496415.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_496418.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_496424.2	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_496425.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_496432.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_496449.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_496452.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_496459.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_496461.1	Catalyzes the reversible oxidation of malate to oxaloacetate
YP_496471.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_496474.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_496478.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_496481.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_496490.1	activates fatty acids by binding to coenzyme A
YP_496501.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_496513.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_496522.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_496523.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_496524.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_496525.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_496526.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_496527.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_496528.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_496529.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_496530.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_496531.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_496532.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_496533.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_496534.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_496535.1	one of the stabilizing components for the large ribosomal subunit
YP_496536.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_496537.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_496538.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_496539.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_496540.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_496541.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_496542.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_496543.1	binds 5S rRNA along with protein L5 and L25
YP_496544.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_496545.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_496546.2	late assembly protein
YP_496547.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_496548.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_496550.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_496553.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_496555.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_496557.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_496560.1	Converts isocitrate to alpha ketoglutarate
YP_496562.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_496579.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_496580.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_496587.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_496594.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_496600.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_496604.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_496616.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_496617.1	carries the fatty acid chain in fatty acid biosynthesis
YP_496621.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
YP_496630.1	catalyzes the interconversion of chorismate to prephenate
YP_496635.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_496644.1	catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_496647.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_496648.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_496649.1	Catalyzes the phosphorylation of UMP to UDP
YP_496650.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_496653.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_496658.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_496667.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane
YP_496680.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_496683.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_496685.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_496686.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_496688.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_496691.1	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile
YP_496692.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_496693.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_496694.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_496695.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_496707.1	binds the polymerase to DNA and acts as a sliding clamp
YP_496721.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_496722.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_496806.1	activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence
YP_496807.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_496836.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_496837.1	activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence
YP_496864.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_496929.1	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate
YP_496931.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_496932.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_496943.1	catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA
YP_496953.1	catalyzes the formation of benzaldehyde from benzoylformate
YP_496967.1	activates fatty acids by binding to coenzyme A
YP_496970.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_497020.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
YP_497032.1	catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin
YP_497037.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_497056.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_497058.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_497071.1	catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine
YP_497077.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_497080.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_497083.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_497098.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_497109.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
YP_497113.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_497124.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_497125.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_497126.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein
YP_497127.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein
YP_497167.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_497169.1	catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate
YP_497173.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_497174.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_497177.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_497183.1	catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase
YP_497189.1	TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine
YP_497192.1	negatively supercoils closed circular double-stranded DNA
YP_497195.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_497199.1	bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations
YP_497205.1	stimulates the elongation of poly(A) tails
YP_497224.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_497230.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_497232.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_497238.1	catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis
YP_497239.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_497258.1	catalyzes the phosphorylation of NAD to NADP
YP_497264.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_497266.1	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
YP_497276.1	catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine
YP_497290.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_497296.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_497297.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_497302.1	Represses a number of genes involved in the response to DNA damage
YP_497316.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_497326.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_497327.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_497333.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_497334.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_497335.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_497336.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_497346.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_497350.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
YP_497354.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
YP_497359.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_497363.1	associated with various cellular activities
YP_497367.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_497383.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_497385.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_497388.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_497389.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_497394.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_497400.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_497401.1	functions in MreBCD complex in some organisms
YP_497402.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_497488.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_497495.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_497501.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_497502.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_497503.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_497506.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_497511.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_497516.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_497518.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_497521.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_497523.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_497525.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
YP_497527.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_497531.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_497533.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_497534.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_497550.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_497556.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_497558.1	Catalyzes the transfer of electrons from NADH to quinone
YP_497560.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_497563.1	Catalyzes the transfer of electrons from NADH to quinone
YP_497565.1	Catalyzes the transfer of electrons from NADH to quinone
YP_497566.1	part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase
YP_497571.1	Catalyzes the transfer of electrons from NADH to quinone
YP_497573.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_497593.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_497620.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_497622.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_497630.1	class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine
YP_497635.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_497637.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_497638.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_497649.1	catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis
YP_497660.1	similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity
YP_497663.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_497669.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_497670.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_497671.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_497672.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_497673.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex
YP_497706.1	catalyzes the formation of protocatechuate from 4-hydroxybenzoate
YP_497712.1	in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane
YP_497753.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_497757.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
YP_497758.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_497760.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_497762.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_497772.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_497796.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_497797.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_497798.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_497799.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_497806.1	catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis
YP_497808.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_497821.1	NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis
YP_497830.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
YP_497839.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_497847.1	CcoO; FixO
YP_497848.1	CcoN; FixN
YP_497855.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_497857.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_497865.1	YghU; B2989; one of eight  glutathione transferases from E. coli
YP_497904.1	heat shock protein involved in degradation of misfolded proteins
YP_497905.1	heat shock protein involved in degradation of misfolded proteins
YP_497926.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_497930.1	protein associated with Co2+ and Mg2+ efflux
YP_497932.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_497941.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_497947.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_497949.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate
YP_497950.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_497953.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_498050.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_498054.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_498055.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_498056.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_498063.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_498082.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_498083.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_498101.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_498102.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_498103.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_498105.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_498128.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_498132.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
YP_498163.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_498165.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_498166.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_498177.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_498188.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
YP_498189.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_498243.1	Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group
YP_498314.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_498323.1	binds and unfolds substrates as part of the ClpXP protease
YP_498324.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_498328.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_498330.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_498409.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
YP_498410.1	DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine
YP_498430.1	activates fatty acids by binding to coenzyme A
YP_498439.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_498456.1	phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin
YP_498457.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_498484.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_498521.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_498522.1	in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis
YP_498525.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_498528.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme
YP_498532.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_498534.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_498542.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif
YP_498554.1	forms a direct contact with the tRNA during translation
YP_498555.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_498559.1	fusion of thiS and thiG; functions in thiamine (vitamin B1) biosynthesis
YP_498560.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
YP_498562.1	This protein performs the mismatch recognition step during the DNA repair process
YP_498563.1	Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_498566.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_498569.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_498572.1	Involved in ubiquinone biosynthesis
YP_498573.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_498588.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_498607.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001165605.1	PFAM: amidohydrolase 2
YP_001165606.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001165607.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165608.1	PFAM: dihydrodipicolinate synthetase
YP_001165609.1	catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol
YP_001165610.1	PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase
YP_001165611.1	PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; 4-vinyl reductase, 4VR; Activator of aromatic catabolism; SMART: AAA ATPase
YP_001165612.1	PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein
YP_001165613.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001165614.1	PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein
YP_001165615.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001165616.1	PFAM: fatty acid desaturase
YP_001165617.1	PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein
YP_001165618.1	Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate
YP_001165619.1	PFAM: aldehyde dehydrogenase
YP_001165620.1	PFAM: ferredoxin
YP_001165621.1	TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase
YP_001165622.1	PFAM: Hydratase/decarboxylase
YP_001165623.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_001165624.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_001165625.1	PFAM: Hydratase/decarboxylase
YP_001165626.1	PFAM: aldehyde dehydrogenase
YP_001165627.1	PFAM: protein of unknown function DUF336
YP_001165628.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001165629.1	PFAM: alpha/beta hydrolase fold
YP_001165630.1	PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain
YP_001165631.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001165632.1	PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein
YP_001165633.1	PFAM: Pyridoxal phosphate biosynthetic protein PdxA
YP_001165634.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001165635.1	PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein
YP_001165636.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001165637.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165638.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001165639.1	PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein
YP_001165640.1	PFAM: DSBA oxidoreductase
YP_001165641.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165642.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165643.1	TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase
YP_001165644.1	TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein
YP_001165646.1	PFAM: FAD linked oxidase domain protein
YP_001165647.1	PFAM: aldehyde dehydrogenase
YP_001165648.1	TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein
YP_001165650.1	PFAM: FAD linked oxidase domain protein
YP_001165653.1	PFAM: alpha/beta hydrolase fold
YP_001165654.1	TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase
YP_001165655.1	PFAM: HpcH/HpaI aldolase
YP_001165656.1	PFAM: L-carnitine dehydratase/bile acid-inducible protein F
YP_001165657.1	PFAM: major facilitator superfamily MFS_1
YP_001165658.1	PFAM: regulatory protein, IclR
YP_001165659.1	PFAM: fatty acid desaturase
YP_001165661.1	TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein
YP_001165662.1	PFAM: BphX family protein
YP_001165663.1	PFAM: protein of unknown function DUF1330
YP_001165664.1	TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase
YP_001165665.1	PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein
YP_001165666.1	PFAM: dihydrodipicolinate synthetase
YP_001165667.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_001165668.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein
YP_001165669.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001165670.1	PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein
YP_001165671.1	PFAM: protein of unknown function DUF6, transmembrane
YP_001165672.1	TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1
YP_001165673.1	TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein
YP_001165674.1	TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein
YP_001165675.1	PFAM: thioesterase superfamily protein
YP_001165676.1	PFAM: alpha/beta hydrolase fold
YP_001165677.1	PFAM: regulatory protein, MarR; transcriptional regulator TrmB
YP_001165681.1	PFAM: sigma-70 region 2 domain protein
YP_001165683.1	PFAM: Resolvase, N-terminal domain
YP_001165685.1	PFAM: WGR domain protein
YP_001165686.1	TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease
YP_001165687.1	PFAM: Cobyrinic acid a,c-diamide synthase
YP_001165688.1	PFAM: plasmid encoded RepA protein
YP_001165689.1	PFAM: TOPRIM domain protein; SMART: Toprim sub domain protein
YP_001165691.1	PFAM: filamentation induced by cAMP protein Fic
YP_001165693.1	TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein, MerR
YP_001165694.1	TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease
YP_001165696.1	PFAM: intron maturase, type II; RNA-directed DNA polymerase (Reverse transcriptase)
YP_001165697.1	PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein
YP_001165699.1	PFAM: phage integrase family protein
YP_001165700.1	PFAM: domain of unknown function DUF1738
YP_001165705.1	PFAM: intron maturase, type II; RNA-directed DNA polymerase (Reverse transcriptase)
YP_001165714.1	PFAM: Radical SAM domain protein
YP_001165718.1	PFAM: protein of unknown function DUF736
YP_001165721.1	PFAM: protein of unknown function DUF159
YP_001165726.1	PFAM: protein of unknown function DUF1173
YP_001165728.1	PFAM: pentapeptide repeat protein
YP_001165729.1	PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2
YP_001165732.1	PFAM: nuclease (SNase domain protein)
YP_001165734.1	PFAM: single-strand binding protein/Primosomal replication protein n
YP_001165735.1	PFAM: ROSMUCR transcriptional regulator
YP_001165737.1	PFAM: phage integrase family protein
YP_001165738.1	PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein
YP_001165739.1	TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein
YP_001165740.1	PFAM: PilT protein domain protein
YP_001165743.1	PFAM: filamentation induced by cAMP protein Fic
YP_001165749.1	PFAM: CopG domain protein DNA-binding domain protein
YP_001165755.1	PFAM: type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like
YP_001165758.1	PFAM: regulatory protein GntR, HTH; GntR domain protein
YP_001165762.1	PFAM: TraH family protein
YP_001165765.1	PFAM: Mating pair stabilisation TraN
YP_001165767.1	PFAM: TraU family protein
YP_001165773.1	TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; CagE, TrbE, VirB component of type IV transporter system
YP_001165776.1	PFAM: TraB pilus assembly family protein
YP_001165778.1	PFAM: TraE family protein
YP_001165779.1	PFAM: TraL family protein
YP_001165783.1	PFAM: Lytic transglycosylase, catalytic
YP_001165784.1	PFAM: Dimethylmenaquinone methyltransferase
YP_001165785.1	PFAM: Dimethylmenaquinone methyltransferase
YP_001165786.1	PFAM: Endoribonuclease L-PSP
YP_001165787.1	PFAM: major facilitator superfamily MFS_1
YP_001165788.1	TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1
YP_001165789.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165792.1	PFAM: OmpA/MotB domain protein
YP_001165793.1	TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region
YP_001165794.1	PFAM: transcription elongation factor GreA/GreB domain protein
YP_001165795.1	PFAM: MmgE/PrpD family protein
YP_001165798.1	PFAM: amidohydrolase; Amidohydrolase 3
YP_001165799.1	PFAM: monooxygenase, FAD-binding
YP_001165800.1	PFAM: protein of unknown function DUF336
YP_001165801.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001165802.1	PFAM: fumarylacetoacetate (FAA) hydrolase
YP_001165804.1	PFAM: Rhodanese domain protein
YP_001165805.1	PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001165806.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165807.1	PFAM: Cupin 2, conserved barrel domain protein
YP_001165808.1	PFAM: fumarylacetoacetate (FAA) hydrolase
YP_001165809.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_001165810.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165812.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001165813.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001165814.1	PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase
YP_001165817.1	PFAM: amine oxidase; FAD dependent oxidoreductase
YP_001165818.1	PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR
YP_001165819.1	PFAM: helix-turn-helix, HxlR type
YP_001165820.1	PFAM: regulatory protein, LysR; LysR, substrate-binding
YP_001165821.1	PFAM: dihydrodipicolinate reductase; NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain
YP_001165822.1	PFAM: sulfatase
YP_001165823.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165824.1	PFAM: monooxygenase, FAD-binding
YP_001165825.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165826.1	PFAM: major facilitator superfamily MFS_1
YP_001165827.1	TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain
YP_001165828.1	PFAM: aminotransferase, class I and II
YP_001165831.1	PFAM: Citrate transporter; TrkA-C domain protein
YP_001165833.1	PFAM: Enoyl-CoA hydratase/isomerase
YP_001165834.1	PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR
YP_001165835.1	PFAM: regulatory protein, TetR
YP_001165836.1	PFAM: phosphoribosyltransferase
YP_001165837.1	TIGRFAM: thioredoxin; MJ0042 family finger-like protein; PFAM: Thioredoxin domain
YP_001165838.1	TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein
YP_001165839.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165840.1	PFAM: regulatory protein, MarR
YP_001165841.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein
YP_001165842.1	PFAM: glutathione-dependent formaldehyde-activating, GFA
YP_001165843.1	PFAM: Enoyl-CoA hydratase/isomerase
YP_001165845.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein
YP_001165846.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001165848.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165849.1	PFAM: Alcohol dehydrogenase GroES domain protein
YP_001165851.1	TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter
YP_001165852.1	PFAM: low molecular weight phosphotyrosine protein phosphatase
YP_001165853.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001165854.1	PFAM: regulatory protein, ArsR
YP_001165855.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165856.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein
YP_001165858.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165859.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165860.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein
YP_001165861.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001165862.1	PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; 4-vinyl reductase, 4VR; Activator of aromatic catabolism; SMART: AAA ATPase
YP_001165865.1	PFAM: FAD linked oxidase domain protein
YP_001165866.1	PFAM: cytochrome c, class I
YP_001165867.1	PFAM: aldehyde dehydrogenase
YP_001165869.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165870.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165871.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001165872.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001165873.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001165874.1	PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase
YP_001165875.1	PFAM: AMP-dependent synthetase and ligase
YP_001165876.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165877.1	PFAM: Xylose isomerase domain protein TIM barrel
YP_001165879.1	PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein
YP_001165880.1	PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein
YP_001165884.1	TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein
YP_001165885.1	PFAM: secretion protein HlyD family protein
YP_001165886.1	PFAM: protein of unknown function DUF1656
YP_001165887.1	PFAM: Fusaric acid resistance protein conserved region
YP_001165888.1	PFAM: regulatory protein, LysR; LysR, substrate-binding
YP_001165889.1	catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine
YP_001165890.1	TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein
YP_001165891.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165893.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001165894.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165895.1	PFAM: regulatory protein, TetR
YP_001165896.1	PFAM: major facilitator superfamily MFS_1
YP_001165898.1	PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain
YP_001165899.1	PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator
YP_001165900.1	PFAM: Ribose/galactose isomerase
YP_001165901.1	TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165902.1	PFAM: PfkB domain protein
YP_001165903.1	PFAM: Carboxylesterase, type B
YP_001165904.1	PFAM: Cupin 2, conserved barrel domain protein
YP_001165906.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165908.1	PFAM: glycoside hydrolase, family 43
YP_001165909.1	catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism
YP_001165910.1	PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain
YP_001165911.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165912.1	PFAM: type I phosphodiesterase/nucleotide pyrophosphatase
YP_001165914.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165915.1	PFAM: regulatory protein, TetR
YP_001165916.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165918.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165919.1	PFAM: cytochrome P450
YP_001165920.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165922.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165925.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165926.1	PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase
YP_001165928.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165929.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165930.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001165931.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001165932.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165934.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001165935.1	PFAM: regulatory protein, LuxR
YP_001165937.1	PFAM: alpha/beta hydrolase fold
YP_001165938.1	PFAM: GCN5-related N-acetyltransferase
YP_001165939.1	PFAM: PGAP1 family protein
YP_001165940.1	PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase
YP_001165943.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001165944.1	PFAM: dehydrogenase, E1 component
YP_001165945.1	PFAM: Transketolase, central region; Transketolase domain protein
YP_001165946.1	PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein
YP_001165948.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001165949.1	PFAM: Catalase domain protein
YP_001165950.1	PFAM: Xylose isomerase domain protein TIM barrel
YP_001165951.1	TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1
YP_001165953.1	PFAM: plasmid stabilization system
YP_001165954.1	TIGRFAM: putative addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156
YP_001165955.1	PFAM: Carboxylesterase, type B
YP_001165959.1	PFAM: protein of unknown function DUF1080
YP_001165960.1	PFAM: glutathione-dependent formaldehyde-activating, GFA
YP_001165961.1	PFAM: Xylose isomerase domain protein TIM barrel
YP_001165964.1	PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase
YP_001165965.1	PFAM: regulatory protein, TetR
YP_001165966.1	PFAM: Carotenoid oxygenase
YP_001165967.1	catalyzes the formation of thymine and 2-deoxy-alpha-D-ribose 1-phosphate from thymidine
YP_001165968.1	TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase
YP_001165969.1	PFAM: ABC transporter related; SMART: AAA ATPase
YP_001165970.1	PFAM: protein of unknown function DUF214
YP_001165971.1	TIGRFAM: efflux transporter, RND family, MFP subunit
YP_001165972.1	PFAM: protein of unknown function DUF156
YP_001165973.1	TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein
YP_001165976.1	TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease
YP_001165977.1	PFAM: Cobyrinic acid a,c-diamide synthase
YP_001165978.1	TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein
YP_001165979.1	PFAM: CheW domain protein
YP_001165980.1	PFAM: luciferase family protein
YP_001165981.1	PFAM: regulatory protein, LuxR
YP_001165982.1	PFAM: nuclear transport factor 2
YP_001165983.1	PFAM: Xylose isomerase domain protein TIM barrel
YP_001165984.1	PFAM: AMP-dependent synthetase and ligase
YP_001165985.1	PFAM: amidohydrolase 2
YP_001165986.1	PFAM: short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain
YP_001165987.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001165988.1	PFAM: Amidase
YP_001165989.1	PFAM: NADH:flavin oxidoreductase/NADH oxidase
YP_001165990.1	PFAM: regulatory protein, AsnC/Lrp family
YP_001165991.1	SMART: regulatory protein, AsnC/Lrp family
YP_001165992.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001165993.1	PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR
YP_001165994.1	PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR
YP_001165995.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001165996.1	PFAM: NADH:flavin oxidoreductase/NADH oxidase
YP_001165998.1	PFAM: flavin reductase domain protein, FMN-binding
YP_001165999.1	PFAM: regulatory protein, AsnC/Lrp family; Helix-turn-helix, type 11 domain protein
YP_001166000.1	PFAM: regulatory protein, AsnC/Lrp family
YP_001166001.1	PFAM: Alpha/beta hydrolase fold-3 domain protein
YP_001166002.1	PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase
YP_001166003.1	PFAM: AMP-dependent synthetase and ligase
YP_001166004.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001166005.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166006.1	PFAM: L-carnitine dehydratase/bile acid-inducible protein F
YP_001166007.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_001166008.1	PFAM: regulatory protein, LysR; LysR, substrate-binding
YP_001166009.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001166010.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001166011.1	PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase
YP_001166012.1	PFAM: protein of unknown function DUF1446
YP_001166014.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166016.1	PFAM: Amidohydrolase 3
YP_001166018.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166020.1	PFAM: GTP cyclohydrolase I
YP_001166021.1	PFAM: major facilitator superfamily MFS_1
YP_001166022.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166023.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001166024.1	PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain
YP_001166025.1	PFAM: Xylose isomerase domain protein TIM barrel
YP_001166028.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein
YP_001166029.1	PFAM: regulatory protein, TetR
YP_001166031.1	PFAM: D-aminoacylase domain protein; Amidohydrolase 3
YP_001166032.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001166033.1	PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166034.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001166035.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166036.1	catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine
YP_001166037.1	TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein
YP_001166038.1	PFAM: Alpha/beta hydrolase fold-3 domain protein
YP_001166039.1	PFAM: NAD-dependent epimerase/dehydratase
YP_001166040.1	PFAM: short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR
YP_001166042.1	PFAM: S-adenosyl-L-homocysteine hydrolase; short-chain dehydrogenase/reductase SDR; KR
YP_001166043.1	PFAM: ferredoxin
YP_001166044.1	PFAM: cytochrome P450
YP_001166045.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001166046.1	PFAM: helix-turn-helix- domain containing protein, AraC type
YP_001166048.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166050.1	PFAM: regulatory protein, LysR; LysR, substrate-binding
YP_001166051.1	PFAM: Rieske [2Fe-2S] domain protein
YP_001166052.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166053.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166054.1	PFAM: glycoside hydrolase family 2, immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2, TIM barrel; glycoside hydrolase family 2, sugar binding
YP_001166055.1	PFAM: major facilitator superfamily MFS_1
YP_001166057.1	PFAM: Excinuclease ABC, C subunit domain protein
YP_001166058.1	PFAM: PfkB domain protein
YP_001166060.1	PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein
YP_001166061.1	PFAM: regulatory protein GntR, HTH; GntR domain protein
YP_001166062.1	catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism
YP_001166063.1	PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain
YP_001166064.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein
YP_001166065.1	PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase
YP_001166067.1	PFAM: cytochrome P450
YP_001166069.1	PFAM: Xylose isomerase domain protein TIM barrel
YP_001166070.1	PFAM: aldo/keto reductase
YP_001166071.1	PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase
YP_001166072.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_001166073.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_001166074.1	PFAM: Hydratase/decarboxylase
YP_001166075.1	PFAM: alpha/beta hydrolase fold
YP_001166076.1	PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166077.1	PFAM: Enoyl-CoA hydratase/isomerase
YP_001166079.1	PFAM: regulatory protein, TetR
YP_001166080.1	PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase
YP_001166082.1	PFAM: Endoribonuclease L-PSP
YP_001166083.1	PFAM: alanine racemase domain protein
YP_001166084.1	PFAM: extracellular solute-binding protein, family 5
YP_001166085.1	PFAM: aldehyde dehydrogenase
YP_001166086.1	PFAM: regulatory protein, LysR; LysR, substrate-binding
YP_001166087.1	PFAM: regulatory protein, TetR
YP_001166088.1	PFAM: FAD dependent oxidoreductase
YP_001166089.1	PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166090.1	PFAM: regulatory protein, AsnC/Lrp family; Helix-turn-helix, type 11 domain protein
YP_001166091.1	PFAM: regulatory protein, AsnC/Lrp family
YP_001166092.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166093.1	PFAM: FAD dependent oxidoreductase
YP_001166094.1	PFAM: regulatory protein, TetR
YP_001166096.1	PFAM: regulatory protein, TetR
YP_001166098.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166101.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166102.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166103.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166104.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001166105.1	PFAM: Ethyl tert-butyl ether degradation EthD
YP_001166106.1	PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase
YP_001166108.1	PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein
YP_001166109.1	PFAM: major facilitator superfamily MFS_1
YP_001166110.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166111.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166116.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166117.1	PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein
YP_001166119.1	PFAM: regulatory protein, AsnC/Lrp family
YP_001166120.1	PFAM: regulatory protein, AsnC/Lrp family
YP_001166121.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166123.1	PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR
YP_001166124.1	PFAM: major facilitator superfamily MFS_1
YP_001166125.1	PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase
YP_001166126.1	PFAM: dehydrogenase, E1 component
YP_001166127.1	PFAM: Transketolase, central region; Transketolase domain protein
YP_001166128.1	PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein
YP_001166129.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166132.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166133.1	PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166134.1	PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR
YP_001166135.1	PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
YP_001166136.1	PFAM: coenzyme A transferase
YP_001166138.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_001166139.1	PFAM: 2-nitropropane dioxygenase, NPD
YP_001166140.1	PFAM: Enoyl-CoA hydratase/isomerase
YP_001166141.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001166142.1	PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166143.1	TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase
YP_001166145.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166146.1	PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166147.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001166148.1	PFAM: short-chain dehydrogenase/reductase SDR; KR
YP_001166149.1	PFAM: MaoC domain protein dehydratase
YP_001166150.1	PFAM: nuclear transport factor 2
YP_001166151.1	TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase
YP_001166152.1	PFAM: AMP-dependent synthetase and ligase
YP_001166153.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001166154.1	PFAM: inositol monophosphatase
YP_001166155.1	PFAM: regulatory protein, LuxR
YP_001166156.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166157.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001166159.1	PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B
YP_001166160.1	PFAM: MOFRL domain protein
YP_001166161.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001166163.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166164.1	PFAM: regulatory protein, LuxR
YP_001166165.1	PFAM: acyl-CoA dehydrogenase domain protein
YP_001166166.1	PFAM: EAL domain protein
YP_001166167.1	PFAM: response regulator receiver
YP_001166168.1	PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Cache domain protein
YP_001166169.1	PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein
YP_001166170.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166171.1	PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166175.1	PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III
YP_001166176.1	PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase
YP_001166177.1	TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1
YP_001166178.1	PFAM: secretion protein HlyD family protein
YP_001166179.1	PFAM: regulatory protein, MarR
YP_001166180.1	PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166182.1	PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein
YP_001166186.1	PFAM: regulatory protein, LuxR
YP_001166187.1	TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein
YP_001166188.1	PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein
YP_001166189.1	PFAM: phage integrase family protein
YP_001166191.1	PFAM: flavin reductase domain protein, FMN-binding
YP_001166192.1	PFAM: short-chain dehydrogenase/reductase SDR
YP_001166194.1	PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain
YP_001166196.1	PFAM: aldehyde dehydrogenase
YP_001166197.1	PFAM: helix-turn-helix- domain containing protein, AraC type
YP_001166198.1	PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit
YP_001166199.1	PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein
YP_001166200.1	PFAM: Amidase
YP_001166201.1	PFAM: TonB-dependent receptor; TonB-dependent receptor, plug
YP_001166202.1	PFAM: cytochrome c, class I
YP_001166203.1	PFAM: methylamine dehydrogenase heavy subunit
YP_001166205.1	TIGRFAM: methylamine dehydrogenase accessory protein MauD; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein
YP_001166206.1	PFAM: methylamine dehydrogenase light chain, C terminal domain protein
YP_001166208.1	TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase
YP_001166209.1	TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase
YP_001166210.1	TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase
YP_001166211.1	TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold
YP_001166212.1	PFAM: regulatory protein, LysR; LysR, substrate-binding
YP_001166213.1	TIGRFAM: muconate and chloromuconate cycloisomerase; PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein
YP_001166214.1	PFAM: Muconolactone delta-isomerase
YP_001166215.1	PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein
YP_001166216.1	PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator
YP_001166217.1	PFAM: cytochrome P450