-- dump date   	20140619_223921
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
709991000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
709991000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
709991000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991000004	Walker A motif; other site
709991000005	ATP binding site [chemical binding]; other site
709991000006	Walker B motif; other site
709991000007	arginine finger; other site
709991000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
709991000009	DnaA box-binding interface [nucleotide binding]; other site
709991000010	Uncharacterized conserved protein [Function unknown]; Region: COG1739
709991000011	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
709991000012	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
709991000013	active site
709991000014	Int/Topo IB signature motif; other site
709991000015	DNA binding site [nucleotide binding]
709991000016	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
709991000017	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991000018	AAA domain; Region: AAA_21; pfam13304
709991000019	Walker A/P-loop; other site
709991000020	ATP binding site [chemical binding]; other site
709991000021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991000022	Walker B; other site
709991000023	D-loop; other site
709991000024	H-loop/switch region; other site
709991000025	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
709991000026	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
709991000027	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
709991000028	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
709991000029	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
709991000030	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
709991000031	Immunity protein Imm5; Region: Imm5; pfam14423
709991000032	Immunity protein Imm5; Region: Imm5; pfam14423
709991000033	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991000034	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991000035	Putative methyltransferase; Region: Methyltransf_4; cl17290
709991000036	Protein of unknown function (DUF418); Region: DUF418; pfam04235
709991000037	maltose O-acetyltransferase; Provisional; Region: PRK10092
709991000038	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
709991000039	active site
709991000040	substrate binding site [chemical binding]; other site
709991000041	trimer interface [polypeptide binding]; other site
709991000042	CoA binding site [chemical binding]; other site
709991000043	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
709991000044	putative deacylase active site [active]
709991000045	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
709991000046	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000047	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991000048	FecR protein; Region: FecR; pfam04773
709991000049	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000050	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000051	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991000052	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000053	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991000054	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991000055	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991000056	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991000057	catalytic residues [active]
709991000058	alpha-galactosidase; Region: PLN02808; cl17638
709991000059	Carbohydrate Binding Module family 35 (CBM35); appended mainly to enzymes that bind alpha-D-galactose (CBM35-Gal), including glycoside hydrolase (GH) families GH31 and GH43; Region: CBM35_galactosidase-like; cd04081
709991000060	Ca binding site [ion binding]; other site
709991000061	Peptidase of plants and bacteria; Region: BSP; pfam04450
709991000062	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
709991000063	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
709991000064	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
709991000065	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
709991000066	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
709991000067	active site
709991000068	catalytic residues [active]
709991000069	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
709991000070	putative transporter; Provisional; Region: PRK10484
709991000071	Na binding site [ion binding]; other site
709991000072	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
709991000073	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
709991000074	intersubunit interface [polypeptide binding]; other site
709991000075	active site
709991000076	Zn2+ binding site [ion binding]; other site
709991000077	L-arabinose isomerase; Provisional; Region: PRK02929
709991000078	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
709991000079	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
709991000080	trimer interface [polypeptide binding]; other site
709991000081	putative substrate binding site [chemical binding]; other site
709991000082	putative metal binding site [ion binding]; other site
709991000083	ribulokinase; Provisional; Region: PRK04123
709991000084	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
709991000085	N- and C-terminal domain interface [polypeptide binding]; other site
709991000086	active site
709991000087	MgATP binding site [chemical binding]; other site
709991000088	catalytic site [active]
709991000089	metal binding site [ion binding]; metal-binding site
709991000090	carbohydrate binding site [chemical binding]; other site
709991000091	homodimer interface [polypeptide binding]; other site
709991000092	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
709991000093	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
709991000094	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
709991000095	ligand binding site [chemical binding]; other site
709991000096	Transposase domain (DUF772); Region: DUF772; pfam05598
709991000097	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991000098	probable DNA metabolism protein; Region: SAM_7_link_chp; TIGR03915
709991000099	putative DNA modification/repair radical SAM protein; Region: rSAM_link_UDG; TIGR03916
709991000100	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991000101	FeS/SAM binding site; other site
709991000102	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
709991000103	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
709991000104	nudix motif; other site
709991000105	Membrane protein of unknown function (DUF340); Region: DUF340; pfam03956
709991000106	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
709991000107	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
709991000108	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
709991000109	glyceraldehyde-3-phosphate dehydrogenase; Provisional; Region: PTZ00023
709991000110	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
709991000111	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
709991000112	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
709991000113	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
709991000114	Ligand Binding Site [chemical binding]; other site
709991000115	TilS substrate C-terminal domain; Region: TilS_C; smart00977
709991000116	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
709991000117	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991000118	Walker A/P-loop; other site
709991000119	ATP binding site [chemical binding]; other site
709991000120	Q-loop/lid; other site
709991000121	ABC transporter signature motif; other site
709991000122	Walker B; other site
709991000123	D-loop; other site
709991000124	H-loop/switch region; other site
709991000125	ABC transporter; Region: ABC_tran_2; pfam12848
709991000126	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991000127	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
709991000128	A new structural DNA glycosylase; Region: AlkD_like; cd06561
709991000129	active site
709991000130	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
709991000131	von Willebrand factor type A domain; Region: VWA_2; pfam13519
709991000132	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
709991000133	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
709991000134	P-loop; other site
709991000135	Magnesium ion binding site [ion binding]; other site
709991000136	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
709991000137	Magnesium ion binding site [ion binding]; other site
709991000138	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
709991000139	ParB-like nuclease domain; Region: ParBc; pfam02195
709991000140	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
709991000141	N-acetyl-D-glucosamine binding site [chemical binding]; other site
709991000142	catalytic residue [active]
709991000143	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
709991000144	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
709991000145	Resistant to P. syringae 6; Provisional; Region: PLN03210
709991000146	Domain of unknown function, B. Theta Gene description (DUF3871); Region: DUF3871; pfam12987
709991000147	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
709991000148	MPN+ (JAMM) motif; other site
709991000149	Zinc-binding site [ion binding]; other site
709991000150	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
709991000151	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
709991000152	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991000153	non-specific DNA binding site [nucleotide binding]; other site
709991000154	salt bridge; other site
709991000155	sequence-specific DNA binding site [nucleotide binding]; other site
709991000156	Domain of unknown function (DUF4062); Region: DUF4062; pfam13271
709991000157	Helix-turn-helix domain; Region: HTH_36; pfam13730
709991000158	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
709991000159	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
709991000160	active site
709991000161	DNA binding site [nucleotide binding]
709991000162	Int/Topo IB signature motif; other site
709991000163	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
709991000164	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
709991000165	Phosphotransferase enzyme family; Region: APH; pfam01636
709991000166	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991000167	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
709991000168	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000169	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991000170	DNA binding residues [nucleotide binding]
709991000171	RloB-like protein; Region: RloB; pfam13707
709991000172	AAA domain; Region: AAA_21; pfam13304
709991000173	FecR protein; Region: FecR; pfam04773
709991000174	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991000175	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000176	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000177	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991000178	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991000179	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000180	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991000181	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991000182	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991000183	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991000184	catalytic residues [active]
709991000185	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
709991000186	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991000187	Walker A/P-loop; other site
709991000188	ATP binding site [chemical binding]; other site
709991000189	Q-loop/lid; other site
709991000190	ABC transporter signature motif; other site
709991000191	Walker B; other site
709991000192	D-loop; other site
709991000193	H-loop/switch region; other site
709991000194	ABC transporter; Region: ABC_tran_2; pfam12848
709991000195	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991000196	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000197	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000198	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000199	DNA binding residues [nucleotide binding]
709991000200	FecR protein; Region: FecR; pfam04773
709991000201	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991000202	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000203	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000204	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991000205	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000206	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991000207	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991000208	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991000209	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991000210	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991000211	catalytic residues [active]
709991000212	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991000213	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991000214	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991000215	catalytic residues [active]
709991000216	YodL-like; Region: YodL; pfam14191
709991000217	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
709991000218	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
709991000219	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
709991000220	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
709991000221	HSP70 interaction site [polypeptide binding]; other site
709991000222	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
709991000223	dimer interface [polypeptide binding]; other site
709991000224	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000225	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000226	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000227	DNA binding residues [nucleotide binding]
709991000228	FecR protein; Region: FecR; pfam04773
709991000229	Transposase domain (DUF772); Region: DUF772; pfam05598
709991000230	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991000231	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000232	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000233	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991000234	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991000235	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000236	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991000237	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991000238	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
709991000239	Predicted membrane protein [Function unknown]; Region: COG1971
709991000240	Domain of unknown function DUF; Region: DUF204; pfam02659
709991000241	Domain of unknown function DUF; Region: DUF204; pfam02659
709991000242	GSCFA family; Region: GSCFA; pfam08885
709991000243	Sporulation related domain; Region: SPOR; pfam05036
709991000244	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
709991000245	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
709991000246	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
709991000247	NAD(P) binding site [chemical binding]; other site
709991000248	homodimer interface [polypeptide binding]; other site
709991000249	substrate binding site [chemical binding]; other site
709991000250	active site
709991000251	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
709991000252	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
709991000253	inhibitor-cofactor binding pocket; inhibition site
709991000254	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991000255	catalytic residue [active]
709991000256	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
709991000257	ligand binding site; other site
709991000258	tetramer interface; other site
709991000259	pseudaminic acid biosynthesis-associated protein PseG; Region: PseG; TIGR03590
709991000260	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
709991000261	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
709991000262	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
709991000263	catalytic residue [active]
709991000264	carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767
709991000265	ATP-grasp domain; Region: ATP-grasp_4; cl17255
709991000266	pseudaminic acid synthase; Region: PseI; TIGR03586
709991000267	NeuB family; Region: NeuB; pfam03102
709991000268	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
709991000269	NeuB binding interface [polypeptide binding]; other site
709991000270	putative substrate binding site [chemical binding]; other site
709991000271	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
709991000272	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
709991000273	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991000274	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
709991000275	Acyltransferase family; Region: Acyl_transf_3; pfam01757
709991000276	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
709991000277	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
709991000278	active site
709991000279	Protoporphyrinogen oxidase [Coenzyme metabolism]; Region: HemY; COG1232
709991000280	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
709991000281	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
709991000282	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
709991000283	putative NAD(P) binding site [chemical binding]; other site
709991000284	active site
709991000285	putative substrate binding site [chemical binding]; other site
709991000286	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
709991000287	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
709991000288	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
709991000289	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
709991000290	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
709991000291	active site
709991000292	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
709991000293	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
709991000294	putative ATP binding site [chemical binding]; other site
709991000295	putative substrate interface [chemical binding]; other site
709991000296	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
709991000297	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
709991000298	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
709991000299	active site
709991000300	HIGH motif; other site
709991000301	dimer interface [polypeptide binding]; other site
709991000302	KMSKS motif; other site
709991000303	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
709991000304	RuvA N terminal domain; Region: RuvA_N; pfam01330
709991000305	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
709991000306	potential frameshift: common BLAST hit: gi|188994696|ref|YP_001928948.1| gliding motility protein SprA
709991000307	Motility related/secretion protein; Region: SprA_N; pfam14349
709991000308	Motility related/secretion protein; Region: SprA_N; pfam14349
709991000309	Motility related/secretion protein; Region: SprA_N; pfam14349
709991000310	Motility related/secretion protein; Region: SprA_N; pfam14349
709991000311	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
709991000312	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
709991000313	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
709991000314	S-ribosylhomocysteinase; Provisional; Region: PRK02260
709991000315	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
709991000316	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
709991000317	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
709991000318	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991000319	S-adenosylmethionine binding site [chemical binding]; other site
709991000320	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
709991000321	UbiA prenyltransferase family; Region: UbiA; pfam01040
709991000322	Amidinotransferase; Region: Amidinotransf; cl12043
709991000323	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
709991000324	MgtE intracellular N domain; Region: MgtE_N; smart00924
709991000325	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
709991000326	Divalent cation transporter; Region: MgtE; pfam01769
709991000327	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
709991000328	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991000329	S-adenosylmethionine binding site [chemical binding]; other site
709991000330	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
709991000331	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
709991000332	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
709991000333	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000334	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000335	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000336	DNA binding residues [nucleotide binding]
709991000337	FecR protein; Region: FecR; pfam04773
709991000338	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991000339	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991000340	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000341	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000342	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991000343	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000344	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991000345	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991000346	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
709991000347	active site
709991000348	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
709991000349	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
709991000350	nucleotide binding site [chemical binding]; other site
709991000351	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
709991000352	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
709991000353	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991000354	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991000355	dimer interface [polypeptide binding]; other site
709991000356	phosphorylation site [posttranslational modification]
709991000357	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991000358	ATP binding site [chemical binding]; other site
709991000359	Mg2+ binding site [ion binding]; other site
709991000360	G-X-G motif; other site
709991000361	Response regulator receiver domain; Region: Response_reg; pfam00072
709991000362	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991000363	active site
709991000364	phosphorylation site [posttranslational modification]
709991000365	intermolecular recognition site; other site
709991000366	dimerization interface [polypeptide binding]; other site
709991000367	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
709991000368	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991000369	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
709991000370	active site
709991000371	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
709991000372	Uncharacterized conserved protein [Function unknown]; Region: COG3538
709991000373	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
709991000374	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
709991000375	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991000376	putative substrate translocation pore; other site
709991000377	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
709991000378	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
709991000379	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
709991000380	transcription termination factor Rho; Provisional; Region: rho; PRK09376
709991000381	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
709991000382	RNA binding site [nucleotide binding]; other site
709991000383	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
709991000384	multimer interface [polypeptide binding]; other site
709991000385	Walker A motif; other site
709991000386	ATP binding site [chemical binding]; other site
709991000387	Walker B motif; other site
709991000388	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
709991000389	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
709991000390	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
709991000391	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
709991000392	AAA domain; Region: AAA_14; pfam13173
709991000393	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
709991000394	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
709991000395	dimer interface [polypeptide binding]; other site
709991000396	PYR/PP interface [polypeptide binding]; other site
709991000397	TPP binding site [chemical binding]; other site
709991000398	substrate binding site [chemical binding]; other site
709991000399	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
709991000400	Domain of unknown function; Region: EKR; pfam10371
709991000401	4Fe-4S binding domain; Region: Fer4_6; pfam12837
709991000402	4Fe-4S binding domain; Region: Fer4; pfam00037
709991000403	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
709991000404	TPP-binding site [chemical binding]; other site
709991000405	dimer interface [polypeptide binding]; other site
709991000406	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
709991000407	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
709991000408	active site
709991000409	metal binding site [ion binding]; metal-binding site
709991000410	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
709991000411	active site
709991000412	metal binding site [ion binding]; metal-binding site
709991000413	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
709991000414	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991000415	active site
709991000416	phosphorylation site [posttranslational modification]
709991000417	intermolecular recognition site; other site
709991000418	dimerization interface [polypeptide binding]; other site
709991000419	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991000420	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
709991000421	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
709991000422	putative dimer interface [polypeptide binding]; other site
709991000423	[2Fe-2S] cluster binding site [ion binding]; other site
709991000424	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
709991000425	catalytic loop [active]
709991000426	iron binding site [ion binding]; other site
709991000427	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
709991000428	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
709991000429	4Fe-4S binding domain; Region: Fer4; pfam00037
709991000430	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
709991000431	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
709991000432	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
709991000433	dimer interface [polypeptide binding]; other site
709991000434	[2Fe-2S] cluster binding site [ion binding]; other site
709991000435	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
709991000436	SLBB domain; Region: SLBB; pfam10531
709991000437	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
709991000438	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
709991000439	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
709991000440	dimer interface [polypeptide binding]; other site
709991000441	[2Fe-2S] cluster binding site [ion binding]; other site
709991000442	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991000443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991000444	ATP binding site [chemical binding]; other site
709991000445	Mg2+ binding site [ion binding]; other site
709991000446	G-X-G motif; other site
709991000447	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase; Region: PHP_HisPPase; cd07432
709991000448	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
709991000449	active site
709991000450	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase; Region: PHP_HisPPase; cd07432
709991000451	PHP-associated; Region: PHP_C; pfam13263
709991000452	DRTGG domain; Region: DRTGG; pfam07085
709991000453	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
709991000454	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
709991000455	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
709991000456	Putative Fe-S cluster; Region: FeS; cl17515
709991000457	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
709991000458	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991000459	ATP binding site [chemical binding]; other site
709991000460	Mg2+ binding site [ion binding]; other site
709991000461	G-X-G motif; other site
709991000462	DRTGG domain; Region: DRTGG; pfam07085
709991000463	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
709991000464	Ligase N family; Region: LIGANc; smart00532
709991000465	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
709991000466	nucleotide binding pocket [chemical binding]; other site
709991000467	K-X-D-G motif; other site
709991000468	catalytic site [active]
709991000469	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
709991000470	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
709991000471	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
709991000472	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
709991000473	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
709991000474	Dimer interface [polypeptide binding]; other site
709991000475	BRCT sequence motif; other site
709991000476	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
709991000477	Clp amino terminal domain; Region: Clp_N; pfam02861
709991000478	Clp amino terminal domain; Region: Clp_N; pfam02861
709991000479	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991000480	Walker A motif; other site
709991000481	ATP binding site [chemical binding]; other site
709991000482	Walker B motif; other site
709991000483	arginine finger; other site
709991000484	UvrB/uvrC motif; Region: UVR; pfam02151
709991000485	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991000486	Walker A motif; other site
709991000487	ATP binding site [chemical binding]; other site
709991000488	Walker B motif; other site
709991000489	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
709991000490	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
709991000491	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
709991000492	putative DNA binding site [nucleotide binding]; other site
709991000493	putative Zn2+ binding site [ion binding]; other site
709991000494	AsnC family; Region: AsnC_trans_reg; pfam01037
709991000495	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
709991000496	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
709991000497	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
709991000498	multiple promoter invertase; Provisional; Region: mpi; PRK13413
709991000499	catalytic residues [active]
709991000500	catalytic nucleophile [active]
709991000501	Presynaptic Site I dimer interface [polypeptide binding]; other site
709991000502	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
709991000503	Synaptic Flat tetramer interface [polypeptide binding]; other site
709991000504	Synaptic Site I dimer interface [polypeptide binding]; other site
709991000505	DNA binding site [nucleotide binding]
709991000506	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
709991000507	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000508	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000509	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000510	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991000511	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000512	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991000513	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991000514	Domain of unknown function (DUF4302); Region: DUF4302; pfam14135
709991000515	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
709991000516	Interdomain contacts; other site
709991000517	Cytokine receptor motif; other site
709991000518	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
709991000519	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991000520	gliding motility-associated lipoprotein GldD; Region: GldD_lipo; TIGR03512
709991000521	gliding motility-associated protein GldE; Region: GldE; TIGR03520
709991000522	Domain of unknown function DUF21; Region: DUF21; pfam01595
709991000523	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
709991000524	Transporter associated domain; Region: CorC_HlyC; smart01091
709991000525	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
709991000526	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
709991000527	putative active site [active]
709991000528	putative NTP binding site [chemical binding]; other site
709991000529	putative nucleic acid binding site [nucleotide binding]; other site
709991000530	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
709991000531	Type II intron maturase; Region: Intron_maturas2; pfam01348
709991000532	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
709991000533	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
709991000534	dimer interface [polypeptide binding]; other site
709991000535	ssDNA binding site [nucleotide binding]; other site
709991000536	tetramer (dimer of dimers) interface [polypeptide binding]; other site
709991000537	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
709991000538	IHF - DNA interface [nucleotide binding]; other site
709991000539	IHF dimer interface [polypeptide binding]; other site
709991000540	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
709991000541	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
709991000542	homodimer interface [polypeptide binding]; other site
709991000543	oligonucleotide binding site [chemical binding]; other site
709991000544	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
709991000545	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
709991000546	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
709991000547	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991000548	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000549	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000550	DNA binding residues [nucleotide binding]
709991000551	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
709991000552	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
709991000553	Lipocalin-like; Region: Lipocalin_3; pfam12702
709991000554	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
709991000555	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
709991000556	GTP-binding protein YchF; Reviewed; Region: PRK09601
709991000557	YchF GTPase; Region: YchF; cd01900
709991000558	G1 box; other site
709991000559	GTP/Mg2+ binding site [chemical binding]; other site
709991000560	Switch I region; other site
709991000561	G2 box; other site
709991000562	Switch II region; other site
709991000563	G3 box; other site
709991000564	G4 box; other site
709991000565	G5 box; other site
709991000566	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
709991000567	Glycosyl hydrolase family 43; Region: GH43_5; cd08984
709991000568	active site
709991000569	Glycosyl hydrolase family 43; Region: GH43_ABN_2; cd08999
709991000570	putative substrate binding site [chemical binding]; other site
709991000571	active site
709991000572	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
709991000573	active site
709991000574	catalytic residues [active]
709991000575	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
709991000576	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
709991000577	Uncharacterized conserved protein [Function unknown]; Region: COG1624
709991000578	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
709991000579	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
709991000580	ATP binding site [chemical binding]; other site
709991000581	active site
709991000582	substrate binding site [chemical binding]; other site
709991000583	PhoH-like protein; Region: PhoH; pfam02562
709991000584	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
709991000585	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
709991000586	homodimer interface [polypeptide binding]; other site
709991000587	metal binding site [ion binding]; metal-binding site
709991000588	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
709991000589	homodimer interface [polypeptide binding]; other site
709991000590	active site
709991000591	putative chemical substrate binding site [chemical binding]; other site
709991000592	metal binding site [ion binding]; metal-binding site
709991000593	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
709991000594	catalytic loop [active]
709991000595	iron binding site [ion binding]; other site
709991000596	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
709991000597	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
709991000598	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
709991000599	4Fe-4S binding domain; Region: Fer4; pfam00037
709991000600	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
709991000601	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
709991000602	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
709991000603	S1 domain; Region: S1_2; pfam13509
709991000604	S1 domain; Region: S1_2; pfam13509
709991000605	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
709991000606	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991000607	Walker A/P-loop; other site
709991000608	ATP binding site [chemical binding]; other site
709991000609	Q-loop/lid; other site
709991000610	ABC transporter signature motif; other site
709991000611	Walker B; other site
709991000612	D-loop; other site
709991000613	H-loop/switch region; other site
709991000614	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
709991000615	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
709991000616	substrate binding site [chemical binding]; other site
709991000617	hexamer interface [polypeptide binding]; other site
709991000618	metal binding site [ion binding]; metal-binding site
709991000619	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
709991000620	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
709991000621	trimer interface [polypeptide binding]; other site
709991000622	putative metal binding site [ion binding]; other site
709991000623	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
709991000624	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
709991000625	putative dimer interface [polypeptide binding]; other site
709991000626	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
709991000627	Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins. Dispersin B is a soluble beta-N-acetylglucosamidase found in bacteria that hydrolyzes the beta-1,6-linkages of PGA (poly-beta-(1,6)...; Region: GH20_DspB_LnbB-like; cd06564
709991000628	active site
709991000629	AAA domain; Region: AAA_22; pfam13401
709991000630	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991000631	Walker A motif; other site
709991000632	ATP binding site [chemical binding]; other site
709991000633	Walker B motif; other site
709991000634	Family description; Region: UvrD_C_2; pfam13538
709991000635	HRDC domain; Region: HRDC; pfam00570
709991000636	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
709991000637	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
709991000638	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
709991000639	recombination factor protein RarA; Reviewed; Region: PRK13342
709991000640	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991000641	Walker A motif; other site
709991000642	ATP binding site [chemical binding]; other site
709991000643	Walker B motif; other site
709991000644	arginine finger; other site
709991000645	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
709991000646	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
709991000647	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
709991000648	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
709991000649	Domain of unknown function DUF21; Region: DUF21; pfam01595
709991000650	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
709991000651	Transporter associated domain; Region: CorC_HlyC; smart01091
709991000652	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
709991000653	MutS domain III; Region: MutS_III; pfam05192
709991000654	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991000655	Walker A/P-loop; other site
709991000656	ATP binding site [chemical binding]; other site
709991000657	Q-loop/lid; other site
709991000658	ABC transporter signature motif; other site
709991000659	Walker B; other site
709991000660	D-loop; other site
709991000661	H-loop/switch region; other site
709991000662	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
709991000663	Smr domain; Region: Smr; pfam01713
709991000664	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991000665	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991000666	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991000667	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991000668	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
709991000669	16S/18S rRNA binding site [nucleotide binding]; other site
709991000670	S13e-L30e interaction site [polypeptide binding]; other site
709991000671	25S rRNA binding site [nucleotide binding]; other site
709991000672	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
709991000673	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
709991000674	RNase E interface [polypeptide binding]; other site
709991000675	trimer interface [polypeptide binding]; other site
709991000676	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
709991000677	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
709991000678	RNase E interface [polypeptide binding]; other site
709991000679	trimer interface [polypeptide binding]; other site
709991000680	active site
709991000681	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
709991000682	putative nucleic acid binding region [nucleotide binding]; other site
709991000683	G-X-X-G motif; other site
709991000684	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
709991000685	RNA binding site [nucleotide binding]; other site
709991000686	domain interface; other site
709991000687	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; pfam00596
709991000688	active site
709991000689	Zn2+ binding site [ion binding]; other site
709991000690	intersubunit interface [polypeptide binding]; other site
709991000691	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
709991000692	Pyridoxal phosphate biosynthetic protein PdxA; Region: PdxA; cl00873
709991000693	NVEALA protein; Region: NVEALA; pfam14055
709991000694	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
709991000695	Clostripain family; Region: Peptidase_C11; pfam03415
709991000696	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
709991000697	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
709991000698	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
709991000699	putative ADP-ribose binding site [chemical binding]; other site
709991000700	putative active site [active]
709991000701	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991000702	Major Facilitator Superfamily; Region: MFS_1; pfam07690
709991000703	putative substrate translocation pore; other site
709991000704	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
709991000705	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
709991000706	active site
709991000707	Na/Ca binding site [ion binding]; other site
709991000708	catalytic site [active]
709991000709	Domain of unknown function (DUF1939); Region: DUF1939; pfam09154
709991000710	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
709991000711	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
709991000712	Ca binding site [ion binding]; other site
709991000713	active site
709991000714	catalytic site [active]
709991000715	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
709991000716	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991000717	ATP binding site [chemical binding]; other site
709991000718	putative Mg++ binding site [ion binding]; other site
709991000719	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991000720	nucleotide binding region [chemical binding]; other site
709991000721	ATP-binding site [chemical binding]; other site
709991000722	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
709991000723	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
709991000724	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
709991000725	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
709991000726	tetramer interface [polypeptide binding]; other site
709991000727	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991000728	catalytic residue [active]
709991000729	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
709991000730	ABC1 family; Region: ABC1; cl17513
709991000731	putative transporter; Validated; Region: PRK03818
709991000732	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
709991000733	TrkA-C domain; Region: TrkA_C; pfam02080
709991000734	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
709991000735	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
709991000736	NlpC/P60 family; Region: NLPC_P60; pfam00877
709991000737	WbqC-like protein family; Region: WbqC; pfam08889
709991000738	1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]; Region: GlgB; COG0296
709991000739	N-terminal Early set domain associated with the catalytic domain of eukaryotic glycogen branching enzyme (also called 1,4 alpha glucan branching enzyme); Region: E_set_GBE_euk_N; cd02854
709991000740	Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes; Region: AmyAc_bac_euk_BE; cd11321
709991000741	active site
709991000742	catalytic site [active]
709991000743	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
709991000744	Glycogen debranching enzyme N terminal; Region: GDE_N; pfam12439
709991000745	glycogen debranching enzyme, archaeal type, putative; Region: gde_arch; TIGR01561
709991000746	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
709991000747	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
709991000748	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
709991000749	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991000750	N-terminal catalytic domain of a thermoactive alpha-amylase from Methanococcus jannaschii and similar proteins; glycoside hydrolase family 57 (GH57); Region: GH57N_MJA1_like; cd10795
709991000751	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
709991000752	putative active site [active]
709991000753	catalytic site [active]
709991000754	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
709991000755	Glycogen synthase; Region: Glycogen_syn; pfam05693
709991000756	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
709991000757	putative homodimer interface [polypeptide binding]; other site
709991000758	putative active site pocket [active]
709991000759	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
709991000760	thymidine kinase; Provisional; Region: PRK04296
709991000761	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000762	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000763	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000764	DNA binding residues [nucleotide binding]
709991000765	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
709991000766	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
709991000767	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
709991000768	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991000769	ATP binding site [chemical binding]; other site
709991000770	putative Mg++ binding site [ion binding]; other site
709991000771	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991000772	nucleotide binding region [chemical binding]; other site
709991000773	ATP-binding site [chemical binding]; other site
709991000774	Part of AAA domain; Region: AAA_19; pfam13245
709991000775	AAA domain; Region: AAA_30; pfam13604
709991000776	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
709991000777	Family description; Region: UvrD_C_2; pfam13538
709991000778	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
709991000779	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
709991000780	nucleotide binding site [chemical binding]; other site
709991000781	NEF interaction site [polypeptide binding]; other site
709991000782	SBD interface [polypeptide binding]; other site
709991000783	cysteate synthase; Region: cysteate_syn; TIGR03844
709991000784	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
709991000785	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991000786	catalytic residue [active]
709991000787	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
709991000788	Predicted permeases [General function prediction only]; Region: COG0795
709991000789	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
709991000790	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
709991000791	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
709991000792	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
709991000793	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
709991000794	putative active site [active]
709991000795	substrate binding site [chemical binding]; other site
709991000796	putative cosubstrate binding site; other site
709991000797	catalytic site [active]
709991000798	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
709991000799	substrate binding site [chemical binding]; other site
709991000800	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000801	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000802	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991000803	DNA binding residues [nucleotide binding]
709991000804	FecR protein; Region: FecR; pfam04773
709991000805	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991000806	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991000807	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000808	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000809	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991000810	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
709991000811	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000812	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991000813	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
709991000814	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991000815	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
709991000816	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991000817	Walker A motif; other site
709991000818	ATP binding site [chemical binding]; other site
709991000819	Walker B motif; other site
709991000820	arginine finger; other site
709991000821	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
709991000822	methionine sulfoxide reductase B; Provisional; Region: PRK00222
709991000823	SelR domain; Region: SelR; pfam01641
709991000824	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
709991000825	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
709991000826	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
709991000827	NAD(P) binding site [chemical binding]; other site
709991000828	active site
709991000829	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
709991000830	MiaB-like tRNA modifying enzyme; Region: MiaB-like-C; TIGR01579
709991000831	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
709991000832	FeS/SAM binding site; other site
709991000833	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
709991000834	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
709991000835	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
709991000836	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991000837	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991000838	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991000839	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
709991000840	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
709991000841	Walker A/P-loop; other site
709991000842	ATP binding site [chemical binding]; other site
709991000843	Q-loop/lid; other site
709991000844	ABC transporter signature motif; other site
709991000845	Walker B; other site
709991000846	D-loop; other site
709991000847	H-loop/switch region; other site
709991000848	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991000849	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
709991000850	FtsX-like permease family; Region: FtsX; pfam02687
709991000851	Histidine kinase; Region: His_kinase; pfam06580
709991000852	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
709991000853	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991000854	active site
709991000855	phosphorylation site [posttranslational modification]
709991000856	intermolecular recognition site; other site
709991000857	dimerization interface [polypeptide binding]; other site
709991000858	LytTr DNA-binding domain; Region: LytTR; smart00850
709991000859	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
709991000860	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
709991000861	TrkA-C domain; Region: TrkA_C; pfam02080
709991000862	TrkA-C domain; Region: TrkA_C; pfam02080
709991000863	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991000864	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
709991000865	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
709991000866	NAD binding pocket [chemical binding]; other site
709991000867	beta-alpha-beta structure motif; other site
709991000868	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
709991000869	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
709991000870	MG2 domain; Region: A2M_N; pfam01835
709991000871	Initiator Replication protein; Region: Rep_3; pfam01051
709991000872	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
709991000873	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
709991000874	active site
709991000875	Zn binding site [ion binding]; other site
709991000876	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000877	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000878	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000879	DNA binding residues [nucleotide binding]
709991000880	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
709991000881	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
709991000882	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
709991000883	active site
709991000884	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
709991000885	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
709991000886	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000887	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000888	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000889	DNA binding residues [nucleotide binding]
709991000890	FecR protein; Region: FecR; pfam04773
709991000891	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991000892	Transposase domain (DUF772); Region: DUF772; pfam05598
709991000893	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991000894	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
709991000895	putative catalytic site [active]
709991000896	putative metal binding site [ion binding]; other site
709991000897	putative phosphate binding site [ion binding]; other site
709991000898	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
709991000899	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
709991000900	LytB protein; Region: LYTB; cl00507
709991000901	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
709991000902	6-phosphofructokinase; Provisional; Region: PRK03202
709991000903	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
709991000904	active site
709991000905	ADP/pyrophosphate binding site [chemical binding]; other site
709991000906	dimerization interface [polypeptide binding]; other site
709991000907	allosteric effector site; other site
709991000908	fructose-1,6-bisphosphate binding site; other site
709991000909	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991000910	primosomal protein N' Region: priA; TIGR00595
709991000911	ATP binding site [chemical binding]; other site
709991000912	putative Mg++ binding site [ion binding]; other site
709991000913	helicase superfamily c-terminal domain; Region: HELICc; smart00490
709991000914	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991000915	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991000916	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991000917	DNA binding residues [nucleotide binding]
709991000918	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991000919	FecR protein; Region: FecR; pfam04773
709991000920	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991000921	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991000922	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991000923	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991000924	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991000925	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
709991000926	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
709991000927	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
709991000928	putative active site [active]
709991000929	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991000930	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991000931	Walker A/P-loop; other site
709991000932	ATP binding site [chemical binding]; other site
709991000933	Q-loop/lid; other site
709991000934	ABC transporter signature motif; other site
709991000935	Walker B; other site
709991000936	D-loop; other site
709991000937	H-loop/switch region; other site
709991000938	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991000939	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991000940	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991000941	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991000942	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991000943	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991000944	Ion channel; Region: Ion_trans_2; pfam07885
709991000945	glutaminase; Reviewed; Region: PRK12356
709991000946	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
709991000947	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
709991000948	chorismate binding enzyme; Region: Chorismate_bind; cl10555
709991000949	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
709991000950	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
709991000951	dimer interface [polypeptide binding]; other site
709991000952	tetramer interface [polypeptide binding]; other site
709991000953	PYR/PP interface [polypeptide binding]; other site
709991000954	TPP binding site [chemical binding]; other site
709991000955	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
709991000956	TPP-binding site [chemical binding]; other site
709991000957	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
709991000958	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
709991000959	substrate binding site [chemical binding]; other site
709991000960	oxyanion hole (OAH) forming residues; other site
709991000961	trimer interface [polypeptide binding]; other site
709991000962	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
709991000963	o-succinylbenzoate synthase; Region: menC_gamma/gm+; TIGR01927
709991000964	active site
709991000965	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
709991000966	AMP binding site [chemical binding]; other site
709991000967	active site
709991000968	acyl-activating enzyme (AAE) consensus motif; other site
709991000969	CoA binding site [chemical binding]; other site
709991000970	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991000971	Major Facilitator Superfamily; Region: MFS_1; pfam07690
709991000972	putative substrate translocation pore; other site
709991000973	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
709991000974	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991000975	FeS/SAM binding site; other site
709991000976	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
709991000977	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991000978	S-adenosylmethionine binding site [chemical binding]; other site
709991000979	NHAD transporter family protein; Provisional; Region: PLN00137; cl17324
709991000980	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
709991000981	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991000982	non-specific DNA binding site [nucleotide binding]; other site
709991000983	salt bridge; other site
709991000984	sequence-specific DNA binding site [nucleotide binding]; other site
709991000985	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
709991000986	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
709991000987	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
709991000988	Domain of unknown function (DUF2027); Region: DUF2027; pfam09640
709991000989	Smr domain; Region: Smr; cl02619
709991000990	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
709991000991	peroxiredoxin; Provisional; Region: PRK13189
709991000992	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991000993	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cl00248
709991000994	substrate binding site [chemical binding]; other site
709991000995	dimerization interface [polypeptide binding]; other site
709991000996	active site
709991000997	calcium binding site [ion binding]; other site
709991000998	urocanate hydratase; Provisional; Region: PRK05414
709991000999	EamA-like transporter family; Region: EamA; cl17759
709991001000	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
709991001001	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
709991001002	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
709991001003	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
709991001004	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
709991001005	CoA binding domain; Region: CoA_binding; pfam02629
709991001006	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
709991001007	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
709991001008	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
709991001009	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
709991001010	active site
709991001011	dimer interface [polypeptide binding]; other site
709991001012	motif 1; other site
709991001013	motif 2; other site
709991001014	motif 3; other site
709991001015	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
709991001016	anticodon binding site; other site
709991001017	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
709991001018	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
709991001019	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
709991001020	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
709991001021	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
709991001022	23S rRNA binding site [nucleotide binding]; other site
709991001023	L21 binding site [polypeptide binding]; other site
709991001024	L13 binding site [polypeptide binding]; other site
709991001025	dihydrodipicolinate reductase; Provisional; Region: PRK00048
709991001026	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
709991001027	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
709991001028	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
709991001029	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
709991001030	Catalytic site [active]
709991001031	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
709991001032	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
709991001033	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
709991001034	putative active site [active]
709991001035	PhoH-like protein; Region: PhoH; pfam02562
709991001036	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
709991001037	DJ-1 family protein; Region: not_thiJ; TIGR01383
709991001038	conserved cys residue [active]
709991001039	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991001040	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991001041	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991001042	FecR protein; Region: FecR; pfam04773
709991001043	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991001044	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991001045	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
709991001046	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
709991001047	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
709991001048	Cysteine-rich domain; Region: CCG; pfam02754
709991001049	Cysteine-rich domain; Region: CCG; pfam02754
709991001050	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
709991001051	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
709991001052	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
709991001053	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
709991001054	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
709991001055	Cysteine-rich domain; Region: CCG; pfam02754
709991001056	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
709991001057	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
709991001058	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
709991001059	active site
709991001060	putative DNA-binding cleft [nucleotide binding]; other site
709991001061	dimer interface [polypeptide binding]; other site
709991001062	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
709991001063	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991001064	binding surface
709991001065	TPR motif; other site
709991001066	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991001067	binding surface
709991001068	TPR motif; other site
709991001069	seryl-tRNA synthetase; Provisional; Region: PRK05431
709991001070	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
709991001071	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
709991001072	dimer interface [polypeptide binding]; other site
709991001073	active site
709991001074	motif 1; other site
709991001075	motif 2; other site
709991001076	motif 3; other site
709991001077	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
709991001078	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
709991001079	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991001080	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
709991001081	putative active site [active]
709991001082	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
709991001083	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
709991001084	Double zinc ribbon; Region: DZR; pfam12773
709991001085	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
709991001086	Double zinc ribbon; Region: DZR; pfam12773
709991001087	TrkA-N domain; Region: TrkA_N; pfam02254
709991001088	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
709991001089	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Region: LPLAT_ABO13168-like; cd07988
709991001090	putative acyl-acceptor binding pocket; other site
709991001091	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
709991001092	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
709991001093	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
709991001094	ATP-binding site [chemical binding]; other site
709991001095	Sugar specificity; other site
709991001096	Pyrimidine base specificity; other site
709991001097	C-N hydrolase family amidase; Provisional; Region: PRK10438
709991001098	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
709991001099	active site
709991001100	catalytic triad [active]
709991001101	dimer interface [polypeptide binding]; other site
709991001102	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
709991001103	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
709991001104	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
709991001105	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991001106	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
709991001107	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
709991001108	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
709991001109	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
709991001110	RNA binding site [nucleotide binding]; other site
709991001111	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
709991001112	RNA binding site [nucleotide binding]; other site
709991001113	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
709991001114	RNA binding site [nucleotide binding]; other site
709991001115	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
709991001116	RNA binding site [nucleotide binding]; other site
709991001117	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
709991001118	RNA binding site [nucleotide binding]; other site
709991001119	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
709991001120	RNA binding site [nucleotide binding]; other site
709991001121	ribonuclease Z; Region: RNase_Z; TIGR02651
709991001122	Glycosyl hydrolase family 76; Region: Glyco_hydro_76; pfam03663
709991001123	potential frameshift: common BLAST hit: gi|150006492|ref|YP_001301236.1|  transposase
709991001124	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991001125	Transposase domain (DUF772); Region: DUF772; pfam05598
709991001126	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001127	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991001128	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991001129	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991001130	DNA binding residues [nucleotide binding]
709991001131	FecR protein; Region: FecR; pfam04773
709991001132	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991001133	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991001134	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001135	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991001136	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001137	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991001138	SusD family; Region: SusD; pfam07980
709991001139	Transposase domain (DUF772); Region: DUF772; pfam05598
709991001140	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991001141	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991001142	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991001143	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001144	catalytic residues [active]
709991001145	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
709991001146	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
709991001147	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991001148	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991001149	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001150	catalytic residues [active]
709991001151	Response regulator receiver domain; Region: Response_reg; pfam00072
709991001152	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991001153	active site
709991001154	phosphorylation site [posttranslational modification]
709991001155	intermolecular recognition site; other site
709991001156	dimerization interface [polypeptide binding]; other site
709991001157	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991001158	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
709991001159	dimer interface [polypeptide binding]; other site
709991001160	phosphorylation site [posttranslational modification]
709991001161	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991001162	ATP binding site [chemical binding]; other site
709991001163	Mg2+ binding site [ion binding]; other site
709991001164	G-X-G motif; other site
709991001165	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
709991001166	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
709991001167	Substrate binding site; other site
709991001168	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
709991001169	substrate binding site [chemical binding]; other site
709991001170	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
709991001171	active site
709991001172	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
709991001173	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
709991001174	substrate binding pocket [chemical binding]; other site
709991001175	glycerate kinase; Region: TIGR00045
709991001176	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
709991001177	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
709991001178	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991001179	nucleotide binding region [chemical binding]; other site
709991001180	ATP-binding site [chemical binding]; other site
709991001181	SEC-C motif; Region: SEC-C; pfam02810
709991001182	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
709991001183	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
709991001184	nucleoside/Zn binding site; other site
709991001185	dimer interface [polypeptide binding]; other site
709991001186	catalytic motif [active]
709991001187	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991001188	FecR protein; Region: FecR; pfam04773
709991001189	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991001190	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991001191	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001192	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991001193	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001194	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991001195	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991001196	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991001197	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991001198	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001199	catalytic residues [active]
709991001200	Cache domain; Region: Cache_1; pfam02743
709991001201	Histidine kinase; Region: His_kinase; pfam06580
709991001202	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
709991001203	active site
709991001204	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991001205	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001206	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991001207	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991001208	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991001209	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991001210	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
709991001211	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991001212	active site
709991001213	phosphorylation site [posttranslational modification]
709991001214	intermolecular recognition site; other site
709991001215	dimerization interface [polypeptide binding]; other site
709991001216	LytTr DNA-binding domain; Region: LytTR; smart00850
709991001217	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
709991001218	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991001219	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001220	catalytic residues [active]
709991001221	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991001222	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991001223	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001224	catalytic residues [active]
709991001225	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
709991001226	active site
709991001227	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991001228	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991001229	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991001230	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991001231	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001232	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991001233	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991001234	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001235	FecR protein; Region: FecR; pfam04773
709991001236	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991001237	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991001238	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991001239	DNA binding residues [nucleotide binding]
709991001240	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
709991001241	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991001242	non-specific DNA binding site [nucleotide binding]; other site
709991001243	salt bridge; other site
709991001244	sequence-specific DNA binding site [nucleotide binding]; other site
709991001245	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
709991001246	putative active site [active]
709991001247	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991001248	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001249	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001250	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991001251	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001252	Uncharacterized conserved protein [Function unknown]; Region: COG1944
709991001253	YcaO-like family; Region: YcaO; pfam02624
709991001254	Abi-like protein; Region: Abi_2; cl01988
709991001255	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
709991001256	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
709991001257	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991001258	ATP binding site [chemical binding]; other site
709991001259	putative Mg++ binding site [ion binding]; other site
709991001260	C-terminal putative phospholipase D-like domain of uncharacterized prokaryotic HKD family nucleases fused to DEAD/DEAH box helicases; Region: PLDc_C_DEXD_like; cd09126
709991001261	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991001262	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
709991001263	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
709991001264	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
709991001265	active site
709991001266	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
709991001267	active site
709991001268	oligomerization interface [polypeptide binding]; other site
709991001269	metal binding site [ion binding]; metal-binding site
709991001270	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
709991001271	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
709991001272	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
709991001273	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
709991001274	FtsH Extracellular; Region: FtsH_ext; pfam06480
709991001275	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
709991001276	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991001277	Walker A motif; other site
709991001278	ATP binding site [chemical binding]; other site
709991001279	Walker B motif; other site
709991001280	arginine finger; other site
709991001281	Peptidase family M41; Region: Peptidase_M41; pfam01434
709991001282	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
709991001283	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
709991001284	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991001285	catalytic residue [active]
709991001286	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
709991001287	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
709991001288	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
709991001289	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
709991001290	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991001291	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
709991001292	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991001293	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991001294	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991001295	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991001296	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991001297	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991001298	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991001299	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991001300	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
709991001301	AAA domain; Region: AAA_14; pfam13173
709991001302	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
709991001303	AMP-binding enzyme; Region: AMP-binding; pfam00501
709991001304	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
709991001305	acyl-activating enzyme (AAE) consensus motif; other site
709991001306	putative active site [active]
709991001307	putative AMP binding site [chemical binding]; other site
709991001308	putative CoA binding site [chemical binding]; other site
709991001309	fumarate hydratase; Provisional; Region: PRK15389
709991001310	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
709991001311	Fumarase C-terminus; Region: Fumerase_C; pfam05683
709991001312	Peptidase family M48; Region: Peptidase_M48; pfam01435
709991001313	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
709991001314	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
709991001315	DNA-binding site [nucleotide binding]; DNA binding site
709991001316	UTRA domain; Region: UTRA; pfam07702
709991001317	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
709991001318	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
709991001319	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
709991001320	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
709991001321	NVEALA protein; Region: NVEALA; pfam14055
709991001322	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991001323	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991001324	ATP binding site [chemical binding]; other site
709991001325	Mg2+ binding site [ion binding]; other site
709991001326	G-X-G motif; other site
709991001327	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
709991001328	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
709991001329	Rifin/stevor family; Region: Rifin_STEVOR; cl14106
709991001330	Domain of unknown function (DUF303); Region: DUF303; pfam03629
709991001331	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
709991001332	Domain of unknown function (DUF303); Region: DUF303; pfam03629
709991001333	competence damage-inducible protein A; Provisional; Region: PRK00549
709991001334	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
709991001335	putative MPT binding site; other site
709991001336	Competence-damaged protein; Region: CinA; pfam02464
709991001337	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
709991001338	Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342
709991001339	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991001340	Response regulator receiver domain; Region: Response_reg; pfam00072
709991001341	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991001342	active site
709991001343	phosphorylation site [posttranslational modification]
709991001344	intermolecular recognition site; other site
709991001345	dimerization interface [polypeptide binding]; other site
709991001346	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
709991001347	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
709991001348	Walker A/P-loop; other site
709991001349	ATP binding site [chemical binding]; other site
709991001350	Q-loop/lid; other site
709991001351	ABC transporter signature motif; other site
709991001352	Walker B; other site
709991001353	D-loop; other site
709991001354	H-loop/switch region; other site
709991001355	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991001356	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991001357	FtsX-like permease family; Region: FtsX; pfam02687
709991001358	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
709991001359	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991001360	binding surface
709991001361	TPR motif; other site
709991001362	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991001363	binding surface
709991001364	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991001365	TPR motif; other site
709991001366	TPR repeat; Region: TPR_11; pfam13414
709991001367	Nudix hydrolase homolog; Region: PLN02791
709991001368	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
709991001369	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991001370	recombinase A; Provisional; Region: recA; PRK09354
709991001371	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
709991001372	hexamer interface [polypeptide binding]; other site
709991001373	Walker A motif; other site
709991001374	ATP binding site [chemical binding]; other site
709991001375	Walker B motif; other site
709991001376	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
709991001377	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001378	catalytic triad [active]
709991001379	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
709991001380	CoenzymeA binding site [chemical binding]; other site
709991001381	subunit interaction site [polypeptide binding]; other site
709991001382	PHB binding site; other site
709991001383	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
709991001384	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
709991001385	Sulfotransferase family; Region: Sulfotransfer_3; pfam13469
709991001386	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
709991001387	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
709991001388	CysD dimerization site [polypeptide binding]; other site
709991001389	G1 box; other site
709991001390	putative GEF interaction site [polypeptide binding]; other site
709991001391	GTP/Mg2+ binding site [chemical binding]; other site
709991001392	Switch I region; other site
709991001393	G2 box; other site
709991001394	G3 box; other site
709991001395	Switch II region; other site
709991001396	G4 box; other site
709991001397	G5 box; other site
709991001398	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
709991001399	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
709991001400	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
709991001401	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
709991001402	Active Sites [active]
709991001403	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
709991001404	AAA domain; Region: AAA_33; pfam13671
709991001405	ligand-binding site [chemical binding]; other site
709991001406	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
709991001407	active site
709991001408	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
709991001409	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
709991001410	dimerization interface [polypeptide binding]; other site
709991001411	ATP binding site [chemical binding]; other site
709991001412	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
709991001413	dimerization interface [polypeptide binding]; other site
709991001414	ATP binding site [chemical binding]; other site
709991001415	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
709991001416	putative active site [active]
709991001417	catalytic triad [active]
709991001418	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK12461
709991001419	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
709991001420	active site
709991001421	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
709991001422	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991001423	Protein export membrane protein; Region: SecD_SecF; cl14618
709991001424	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991001425	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991001426	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991001427	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
709991001428	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
709991001429	putative ligand binding site [chemical binding]; other site
709991001430	putative NAD binding site [chemical binding]; other site
709991001431	catalytic site [active]
709991001432	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
709991001433	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
709991001434	metal binding site [ion binding]; metal-binding site
709991001435	dimer interface [polypeptide binding]; other site
709991001436	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
709991001437	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
709991001438	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
709991001439	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
709991001440	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
709991001441	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
709991001442	putative substrate binding site [chemical binding]; other site
709991001443	putative ATP binding site [chemical binding]; other site
709991001444	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
709991001445	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
709991001446	active site
709991001447	Zn binding site [ion binding]; other site
709991001448	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
709991001449	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
709991001450	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
709991001451	Ligand Binding Site [chemical binding]; other site
709991001452	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
709991001453	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
709991001454	substrate-cofactor binding pocket; other site
709991001455	para-aminobenzoate synthase component I; Validated; Region: PRK07093
709991001456	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
709991001457	Glutamine amidotransferase class-I; Region: GATase; pfam00117
709991001458	glutamine binding [chemical binding]; other site
709991001459	catalytic triad [active]
709991001460	MutS domain III; Region: MutS_III; pfam05192
709991001461	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991001462	Walker A/P-loop; other site
709991001463	ATP binding site [chemical binding]; other site
709991001464	Q-loop/lid; other site
709991001465	ABC transporter signature motif; other site
709991001466	Walker B; other site
709991001467	D-loop; other site
709991001468	H-loop/switch region; other site
709991001469	Predicted membrane protein [Function unknown]; Region: COG2860
709991001470	UPF0126 domain; Region: UPF0126; pfam03458
709991001471	UPF0126 domain; Region: UPF0126; pfam03458
709991001472	Cupin domain; Region: Cupin_2; pfam07883
709991001473	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991001474	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001475	catalytic residues [active]
709991001476	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
709991001477	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
709991001478	Conserved TM helix; Region: TM_helix; pfam05552
709991001479	Mechanosensitive ion channel; Region: MS_channel; pfam00924
709991001480	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
709991001481	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
709991001482	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991001483	active site
709991001484	HIGH motif; other site
709991001485	nucleotide binding site [chemical binding]; other site
709991001486	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
709991001487	KMSK motif region; other site
709991001488	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
709991001489	tRNA binding surface [nucleotide binding]; other site
709991001490	anticodon binding site; other site
709991001491	histidinol-phosphatase; Provisional; Region: PRK07328
709991001492	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
709991001493	active site
709991001494	dimer interface [polypeptide binding]; other site
709991001495	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
709991001496	TSCPD domain; Region: TSCPD; cl14834
709991001497	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
709991001498	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
709991001499	active site
709991001500	dimerization interface [polypeptide binding]; other site
709991001501	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
709991001502	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991001503	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
709991001504	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
709991001505	active site
709991001506	nucleophile elbow; other site
709991001507	GMP synthase; Reviewed; Region: guaA; PRK00074
709991001508	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
709991001509	AMP/PPi binding site [chemical binding]; other site
709991001510	candidate oxyanion hole; other site
709991001511	catalytic triad [active]
709991001512	potential glutamine specificity residues [chemical binding]; other site
709991001513	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
709991001514	ATP Binding subdomain [chemical binding]; other site
709991001515	Ligand Binding sites [chemical binding]; other site
709991001516	Dimerization subdomain; other site
709991001517	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
709991001518	DHH family; Region: DHH; pfam01368
709991001519	DHHA1 domain; Region: DHHA1; pfam02272
709991001520	Domain of unknown function (DUF1904); Region: DUF1904; pfam08921
709991001521	Transcriptional regulators [Transcription]; Region: MarR; COG1846
709991001522	MarR family; Region: MarR_2; pfam12802
709991001523	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
709991001524	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
709991001525	metal binding site [ion binding]; metal-binding site
709991001526	dimer interface [polypeptide binding]; other site
709991001527	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
709991001528	GAF domain; Region: GAF_2; pfam13185
709991001529	Transposase domain (DUF772); Region: DUF772; pfam05598
709991001530	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991001531	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991001532	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991001533	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991001534	DNA binding residues [nucleotide binding]
709991001535	DDE superfamily endonuclease; Region: DDE_5; pfam13546
709991001536	FecR protein; Region: FecR; pfam04773
709991001537	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991001538	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001539	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991001540	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001541	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991001542	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991001543	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991001544	catalytic residues [active]
709991001545	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
709991001546	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
709991001547	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
709991001548	dimerization interface 3.5A [polypeptide binding]; other site
709991001549	active site
709991001550	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991001551	Walker A/P-loop; other site
709991001552	ATP binding site [chemical binding]; other site
709991001553	Q-loop/lid; other site
709991001554	exonuclease subunit SbcC; Provisional; Region: PRK10246
709991001555	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991001556	ABC transporter signature motif; other site
709991001557	Walker B; other site
709991001558	D-loop; other site
709991001559	H-loop/switch region; other site
709991001560	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
709991001561	active site
709991001562	metal binding site [ion binding]; metal-binding site
709991001563	DNA binding site [nucleotide binding]
709991001564	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
709991001565	radical SAM enzyme, rSAM/lipoprotein system; Region: rSAM_w_lipo; TIGR04133
709991001566	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991001567	FeS/SAM binding site; other site
709991001568	putative lipoprotein, rSAM/lipoprotein system; Region: lipo_with_rSAM; TIGR04134
709991001569	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991001570	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991001571	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991001572	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991001573	DNA binding residues [nucleotide binding]
709991001574	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
709991001575	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
709991001576	catalytic residue [active]
709991001577	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK07565
709991001578	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
709991001579	phosphate binding site [ion binding]; other site
709991001580	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
709991001581	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
709991001582	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
709991001583	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
709991001584	ATP binding site [chemical binding]; other site
709991001585	substrate interface [chemical binding]; other site
709991001586	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
709991001587	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
709991001588	FeS/SAM binding site; other site
709991001589	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
709991001590	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
709991001591	ThiS interaction site; other site
709991001592	putative active site [active]
709991001593	tetramer interface [polypeptide binding]; other site
709991001594	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
709991001595	thiamine phosphate binding site [chemical binding]; other site
709991001596	active site
709991001597	pyrophosphate binding site [ion binding]; other site
709991001598	HMP-P kinase/thiamin-monophosphate pyrophosphorylase; Region: PLN02898
709991001599	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
709991001600	substrate binding site [chemical binding]; other site
709991001601	dimer interface [polypeptide binding]; other site
709991001602	ATP binding site [chemical binding]; other site
709991001603	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
709991001604	thiamine phosphate binding site [chemical binding]; other site
709991001605	active site
709991001606	pyrophosphate binding site [ion binding]; other site
709991001607	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
709991001608	ThiC-associated domain; Region: ThiC-associated; pfam13667
709991001609	ThiC family; Region: ThiC; pfam01964
709991001610	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
709991001611	thiS-thiF/thiG interaction site; other site
709991001612	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
709991001613	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
709991001614	Major Facilitator Superfamily; Region: MFS_1; pfam07690
709991001615	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991001616	putative substrate translocation pore; other site
709991001617	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
709991001618	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
709991001619	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
709991001620	ligand binding site [chemical binding]; other site
709991001621	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
709991001622	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
709991001623	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
709991001624	Peptidase family U32; Region: Peptidase_U32; pfam01136
709991001625	Collagenase; Region: DUF3656; pfam12392
709991001626	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
709991001627	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
709991001628	glutaminase active site [active]
709991001629	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
709991001630	dimer interface [polypeptide binding]; other site
709991001631	active site
709991001632	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
709991001633	dimer interface [polypeptide binding]; other site
709991001634	active site
709991001635	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
709991001636	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
709991001637	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001638	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
709991001639	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107
709991001640	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
709991001641	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH_2; cd04602
709991001642	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
709991001643	active site
709991001644	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
709991001645	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991001646	active site
709991001647	motif I; other site
709991001648	motif II; other site
709991001649	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
709991001650	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
709991001651	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
709991001652	Domain of unknown function (DUF4294); Region: DUF4294; pfam14127
709991001653	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
709991001654	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
709991001655	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
709991001656	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
709991001657	Bifunctional nuclease; Region: DNase-RNase; pfam02577
709991001658	UvrB/uvrC motif; Region: UVR; pfam02151
709991001659	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
709991001660	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
709991001661	active site
709991001662	dimer interface [polypeptide binding]; other site
709991001663	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
709991001664	dimer interface [polypeptide binding]; other site
709991001665	active site
709991001666	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
709991001667	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
709991001668	active site
709991001669	ADP/pyrophosphate binding site [chemical binding]; other site
709991001670	dimerization interface [polypeptide binding]; other site
709991001671	allosteric effector site; other site
709991001672	fructose-1,6-bisphosphate binding site; other site
709991001673	Formaldehyde dehydrogenases; Region: FDH_like; cd05278
709991001674	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
709991001675	catalytic Zn binding site [ion binding]; other site
709991001676	NAD(P) binding site [chemical binding]; other site
709991001677	structural Zn binding site [ion binding]; other site
709991001678	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
709991001679	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
709991001680	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
709991001681	active site
709991001682	homodimer interface [polypeptide binding]; other site
709991001683	homotetramer interface [polypeptide binding]; other site
709991001684	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
709991001685	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
709991001686	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
709991001687	propionate/acetate kinase; Provisional; Region: PRK12379
709991001688	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
709991001689	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
709991001690	putative protofilament interface [polypeptide binding]; other site
709991001691	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
709991001692	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
709991001693	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
709991001694	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
709991001695	NAD(P) binding site [chemical binding]; other site
709991001696	homotetramer interface [polypeptide binding]; other site
709991001697	homodimer interface [polypeptide binding]; other site
709991001698	active site
709991001699	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
709991001700	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991001701	binding surface
709991001702	Tetratricopeptide repeat; Region: TPR_16; pfam13432
709991001703	TPR motif; other site
709991001704	putative recombination protein RecB; Provisional; Region: PRK13909
709991001705	Family description; Region: UvrD_C_2; pfam13538
709991001706	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
709991001707	Transposase [DNA replication, recombination, and repair]; Region: COG5421
709991001708	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991001709	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001710	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991001711	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991001712	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991001713	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991001714	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991001715	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
709991001716	active site
709991001717	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
709991001718	active site
709991001719	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991001720	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991001721	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991001722	DNA binding residues [nucleotide binding]
709991001723	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
709991001724	hypothetical protein; Validated; Region: PRK02101
709991001725	butyrate kinase; Provisional; Region: PRK03011
709991001726	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
709991001727	Beta-lactamase; Region: Beta-lactamase; pfam00144
709991001728	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
709991001729	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
709991001730	homodimer interface [polypeptide binding]; other site
709991001731	substrate-cofactor binding pocket; other site
709991001732	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991001733	catalytic residue [active]
709991001734	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
709991001735	Uncharacterized conserved protein [Function unknown]; Region: COG5495
709991001736	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
709991001737	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991001738	active site
709991001739	motif I; other site
709991001740	motif II; other site
709991001741	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
709991001742	UbiA prenyltransferase family; Region: UbiA; pfam01040
709991001743	Maf-like protein; Region: Maf; pfam02545
709991001744	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
709991001745	active site
709991001746	dimer interface [polypeptide binding]; other site
709991001747	Peptidase S46; Region: Peptidase_S46; pfam10459
709991001748	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
709991001749	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
709991001750	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
709991001751	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
709991001752	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991001753	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991001754	N-terminal plug; other site
709991001755	ligand-binding site [chemical binding]; other site
709991001756	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
709991001757	metal binding site 2 [ion binding]; metal-binding site
709991001758	putative DNA binding helix; other site
709991001759	metal binding site 1 [ion binding]; metal-binding site
709991001760	dimer interface [polypeptide binding]; other site
709991001761	structural Zn2+ binding site [ion binding]; other site
709991001762	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
709991001763	Rubredoxin; Region: Rubredoxin; pfam00301
709991001764	iron binding site [ion binding]; other site
709991001765	Rubrerythrin [Energy production and conversion]; Region: COG1592
709991001766	rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046
709991001767	diiron binding motif [ion binding]; other site
709991001768	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
709991001769	catalytic core [active]
709991001770	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
709991001771	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
709991001772	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
709991001773	putative active site; other site
709991001774	catalytic residue [active]
709991001775	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
709991001776	putative SAM binding site [chemical binding]; other site
709991001777	homodimer interface [polypeptide binding]; other site
709991001778	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
709991001779	putative hydrolase; Provisional; Region: PRK02113
709991001780	DNA gyrase subunit A; Validated; Region: PRK05560
709991001781	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
709991001782	CAP-like domain; other site
709991001783	active site
709991001784	primary dimer interface [polypeptide binding]; other site
709991001785	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
709991001786	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
709991001787	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
709991001788	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
709991001789	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
709991001790	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
709991001791	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991001792	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991001793	binding surface
709991001794	TPR motif; other site
709991001795	TPR repeat; Region: TPR_11; pfam13414
709991001796	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991001797	TPR motif; other site
709991001798	binding surface
709991001799	TPR repeat; Region: TPR_11; pfam13414
709991001800	TPR repeat; Region: TPR_11; pfam13414
709991001801	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
709991001802	short chain dehydrogenase; Provisional; Region: PRK06181
709991001803	NAD(P) binding site [chemical binding]; other site
709991001804	active site
709991001805	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
709991001806	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
709991001807	YceG-like family; Region: YceG; pfam02618
709991001808	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
709991001809	dimerization interface [polypeptide binding]; other site
709991001810	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
709991001811	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
709991001812	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
709991001813	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
709991001814	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
709991001815	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
709991001816	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
709991001817	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
709991001818	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
709991001819	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
709991001820	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
709991001821	FAD binding pocket [chemical binding]; other site
709991001822	FAD binding motif [chemical binding]; other site
709991001823	phosphate binding motif [ion binding]; other site
709991001824	beta-alpha-beta structure motif; other site
709991001825	NAD binding pocket [chemical binding]; other site
709991001826	Iron coordination center [ion binding]; other site
709991001827	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
709991001828	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
709991001829	heterodimer interface [polypeptide binding]; other site
709991001830	active site
709991001831	FMN binding site [chemical binding]; other site
709991001832	homodimer interface [polypeptide binding]; other site
709991001833	substrate binding site [chemical binding]; other site
709991001834	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
709991001835	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991001836	non-specific DNA binding site [nucleotide binding]; other site
709991001837	salt bridge; other site
709991001838	sequence-specific DNA binding site [nucleotide binding]; other site
709991001839	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
709991001840	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
709991001841	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
709991001842	active site
709991001843	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
709991001844	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991001845	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991001846	DNA binding residues [nucleotide binding]
709991001847	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
709991001848	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
709991001849	purine monophosphate binding site [chemical binding]; other site
709991001850	dimer interface [polypeptide binding]; other site
709991001851	putative catalytic residues [active]
709991001852	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
709991001853	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
709991001854	rod shape-determining protein MreB; Provisional; Region: PRK13927
709991001855	MreB and similar proteins; Region: MreB_like; cd10225
709991001856	nucleotide binding site [chemical binding]; other site
709991001857	Mg binding site [ion binding]; other site
709991001858	putative protofilament interaction site [polypeptide binding]; other site
709991001859	RodZ interaction site [polypeptide binding]; other site
709991001860	rod shape-determining protein MreC; Provisional; Region: PRK13922
709991001861	rod shape-determining protein MreC; Region: MreC; pfam04085
709991001862	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
709991001863	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
709991001864	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
709991001865	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
709991001866	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
709991001867	imidazolonepropionase; Validated; Region: PRK09356
709991001868	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
709991001869	active site
709991001870	glutamate formiminotransferase; Region: FtcD; TIGR02024
709991001871	Formiminotransferase domain, N-terminal subdomain; Region: FTCD_N; pfam07837
709991001872	Formiminotransferase domain; Region: FTCD; pfam02971
709991001873	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
709991001874	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
709991001875	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
709991001876	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
709991001877	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
709991001878	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991001879	motif II; other site
709991001880	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
709991001881	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
709991001882	putative active site [active]
709991001883	putative CoA binding site [chemical binding]; other site
709991001884	nudix motif; other site
709991001885	metal binding site [ion binding]; metal-binding site
709991001886	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
709991001887	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991001888	S-adenosylmethionine binding site [chemical binding]; other site
709991001889	Protein of unknown function (DUF452); Region: DUF452; cl01062
709991001890	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
709991001891	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
709991001892	substrate-cofactor binding pocket; other site
709991001893	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991001894	catalytic residue [active]
709991001895	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06173
709991001896	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
709991001897	inhibitor-cofactor binding pocket; inhibition site
709991001898	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991001899	catalytic residue [active]
709991001900	biotin synthase; Region: bioB; TIGR00433
709991001901	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991001902	FeS/SAM binding site; other site
709991001903	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
709991001904	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
709991001905	Ligand Binding Site [chemical binding]; other site
709991001906	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
709991001907	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
709991001908	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991001909	FeS/SAM binding site; other site
709991001910	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
709991001911	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991001912	ATP binding site [chemical binding]; other site
709991001913	putative Mg++ binding site [ion binding]; other site
709991001914	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991001915	nucleotide binding region [chemical binding]; other site
709991001916	ATP-binding site [chemical binding]; other site
709991001917	peptidyl-prolyl cis-trans isomerase, EpsD family; Region: cis_trans_EpsD; TIGR02925
709991001918	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
709991001919	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
709991001920	SurA N-terminal domain; Region: SurA_N; pfam09312
709991001921	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
709991001922	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
709991001923	MoxR-like ATPases [General function prediction only]; Region: COG0714
709991001924	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991001925	Walker A motif; other site
709991001926	ATP binding site [chemical binding]; other site
709991001927	Walker B motif; other site
709991001928	arginine finger; other site
709991001929	OstA-like protein; Region: OstA_2; pfam13100
709991001930	OstA-like protein; Region: OstA; cl00844
709991001931	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991001932	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
709991001933	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
709991001934	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
709991001935	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
709991001936	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
709991001937	Potassium binding sites [ion binding]; other site
709991001938	Cesium cation binding sites [ion binding]; other site
709991001939	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
709991001940	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
709991001941	putative active site [active]
709991001942	putative metal binding site [ion binding]; other site
709991001943	Transposase domain (DUF772); Region: DUF772; pfam05598
709991001944	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991001945	Cache domain; Region: Cache_1; pfam02743
709991001946	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
709991001947	dimerization interface [polypeptide binding]; other site
709991001948	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
709991001949	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
709991001950	Sulfatase; Region: Sulfatase; pfam00884
709991001951	replicative DNA helicase; Region: DnaB; TIGR00665
709991001952	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
709991001953	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
709991001954	Walker A motif; other site
709991001955	ATP binding site [chemical binding]; other site
709991001956	Walker B motif; other site
709991001957	DNA binding loops [nucleotide binding]
709991001958	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
709991001959	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
709991001960	active site
709991001961	catalytic site [active]
709991001962	substrate binding site [chemical binding]; other site
709991001963	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
709991001964	Enoyl-(Acyl carrier protein) reductase; Region: adh_short_C2; pfam13561
709991001965	NAD binding site [chemical binding]; other site
709991001966	homotetramer interface [polypeptide binding]; other site
709991001967	homodimer interface [polypeptide binding]; other site
709991001968	substrate binding site [chemical binding]; other site
709991001969	active site
709991001970	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
709991001971	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
709991001972	Walker A/P-loop; other site
709991001973	ATP binding site [chemical binding]; other site
709991001974	Q-loop/lid; other site
709991001975	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
709991001976	ABC transporter signature motif; other site
709991001977	Walker B; other site
709991001978	D-loop; other site
709991001979	H-loop/switch region; other site
709991001980	transcription antitermination factor NusB; Region: nusB; TIGR01951
709991001981	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
709991001982	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
709991001983	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991001984	ATP binding site [chemical binding]; other site
709991001985	Mg2+ binding site [ion binding]; other site
709991001986	G-X-G motif; other site
709991001987	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
709991001988	anchoring element; other site
709991001989	dimer interface [polypeptide binding]; other site
709991001990	ATP binding site [chemical binding]; other site
709991001991	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
709991001992	active site
709991001993	putative metal-binding site [ion binding]; other site
709991001994	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
709991001995	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
709991001996	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
709991001997	META domain; Region: META; pfam03724
709991001998	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
709991001999	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
709991002000	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991002001	FeS/SAM binding site; other site
709991002002	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
709991002003	hypothetical protein; Provisional; Region: PRK00955
709991002004	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
709991002005	TPR repeat; Region: TPR_11; pfam13414
709991002006	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002007	binding surface
709991002008	TPR repeat; Region: TPR_11; pfam13414
709991002009	TPR motif; other site
709991002010	TPR repeat; Region: TPR_11; pfam13414
709991002011	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002012	binding surface
709991002013	TPR motif; other site
709991002014	TPR repeat; Region: TPR_11; pfam13414
709991002015	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991002016	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991002017	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991002018	catalytic residues [active]
709991002019	RyR domain; Region: RyR; pfam02026
709991002020	Fic/DOC family; Region: Fic; pfam02661
709991002021	TPR repeat; Region: TPR_11; pfam13414
709991002022	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
709991002023	TPR motif; other site
709991002024	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
709991002025	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
709991002026	ligand binding site [chemical binding]; other site
709991002027	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
709991002028	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
709991002029	hexamer interface [polypeptide binding]; other site
709991002030	ligand binding site [chemical binding]; other site
709991002031	putative active site [active]
709991002032	NAD(P) binding site [chemical binding]; other site
709991002033	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
709991002034	hypothetical protein; Validated; Region: PRK07883
709991002035	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
709991002036	Domain of unknown function DUF59; Region: DUF59; pfam01883
709991002037	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
709991002038	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
709991002039	Protein of unknown function DUF45; Region: DUF45; pfam01863
709991002040	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
709991002041	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
709991002042	substrate binding site [chemical binding]; other site
709991002043	active site
709991002044	catalytic residues [active]
709991002045	heterodimer interface [polypeptide binding]; other site
709991002046	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
709991002047	active site
709991002048	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
709991002049	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
709991002050	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
709991002051	putative active site [active]
709991002052	putative NTP binding site [chemical binding]; other site
709991002053	putative nucleic acid binding site [nucleotide binding]; other site
709991002054	Protein of unknown function (DUF904); Region: DUF904; pfam06005
709991002055	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cl02712
709991002056	amidase catalytic site [active]
709991002057	Zn binding residues [ion binding]; other site
709991002058	substrate binding site [chemical binding]; other site
709991002059	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
709991002060	DDE superfamily endonuclease; Region: DDE_4_2; pfam13613
709991002061	Protein of unknown function (DUF1320); Region: DUF1320; cl01818
709991002062	Protein of unknown function (DUF935); Region: DUF935; pfam06074
709991002063	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
709991002064	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
709991002065	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
709991002066	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
709991002067	chaperone protein DnaJ; Provisional; Region: PRK14289
709991002068	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
709991002069	G1 box; other site
709991002070	GTP/Mg2+ binding site [chemical binding]; other site
709991002071	G2 box; other site
709991002072	Switch I region; other site
709991002073	G3 box; other site
709991002074	Switch II region; other site
709991002075	G4 box; other site
709991002076	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; cl17818
709991002077	AAA domain; Region: AAA_22; pfam13401
709991002078	Mu B transposition protein, C terminal; Region: Phage-MuB_C; pfam09077
709991002079	Integrase core domain; Region: rve; pfam00665
709991002080	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
709991002081	active site
709991002082	ribulose/triose binding site [chemical binding]; other site
709991002083	phosphate binding site [ion binding]; other site
709991002084	substrate (anthranilate) binding pocket [chemical binding]; other site
709991002085	product (indole) binding pocket [chemical binding]; other site
709991002086	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
709991002087	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
709991002088	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
709991002089	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
709991002090	Glutamine amidotransferase class-I; Region: GATase; pfam00117
709991002091	glutamine binding [chemical binding]; other site
709991002092	catalytic triad [active]
709991002093	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
709991002094	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
709991002095	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
709991002096	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
709991002097	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
709991002098	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991002099	catalytic residue [active]
709991002100	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
709991002101	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
709991002102	Tetramer interface [polypeptide binding]; other site
709991002103	active site
709991002104	FMN-binding site [chemical binding]; other site
709991002105	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
709991002106	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
709991002107	L-aspartate oxidase; Provisional; Region: PRK06175
709991002108	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
709991002109	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
709991002110	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
709991002111	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
709991002112	dimerization interface [polypeptide binding]; other site
709991002113	active site
709991002114	Quinolinate synthetase A protein; Region: NadA; pfam02445
709991002115	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
709991002116	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
709991002117	putative tRNA-binding site [nucleotide binding]; other site
709991002118	B3/4 domain; Region: B3_4; pfam03483
709991002119	tRNA synthetase B5 domain; Region: B5; pfam03484
709991002120	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
709991002121	dimer interface [polypeptide binding]; other site
709991002122	motif 1; other site
709991002123	motif 3; other site
709991002124	motif 2; other site
709991002125	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
709991002126	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
709991002127	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
709991002128	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
709991002129	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
709991002130	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
709991002131	Domain of Unknown Function with PDB structure (DUF3858); Region: DUF3858; pfam12970
709991002132	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
709991002133	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991002134	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991002135	Walker A/P-loop; other site
709991002136	ATP binding site [chemical binding]; other site
709991002137	Q-loop/lid; other site
709991002138	ABC transporter signature motif; other site
709991002139	Walker B; other site
709991002140	D-loop; other site
709991002141	H-loop/switch region; other site
709991002142	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
709991002143	Leucine carboxyl methyltransferase; Region: LCM; pfam04072
709991002144	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991002145	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991002146	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
709991002147	dimer interface [polypeptide binding]; other site
709991002148	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991002149	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991002150	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
709991002151	Na2 binding site [ion binding]; other site
709991002152	putative substrate binding site 1 [chemical binding]; other site
709991002153	Na binding site 1 [ion binding]; other site
709991002154	putative substrate binding site 2 [chemical binding]; other site
709991002155	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
709991002156	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
709991002157	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
709991002158	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
709991002159	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
709991002160	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
709991002161	PAS fold; Region: PAS_3; pfam08447
709991002162	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991002163	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991002164	dimer interface [polypeptide binding]; other site
709991002165	phosphorylation site [posttranslational modification]
709991002166	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991002167	ATP binding site [chemical binding]; other site
709991002168	Mg2+ binding site [ion binding]; other site
709991002169	G-X-G motif; other site
709991002170	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
709991002171	active site
709991002172	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
709991002173	lipoyl synthase; Provisional; Region: PRK05481
709991002174	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991002175	FeS/SAM binding site; other site
709991002176	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
709991002177	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
709991002178	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
709991002179	minor groove reading motif; other site
709991002180	helix-hairpin-helix signature motif; other site
709991002181	substrate binding pocket [chemical binding]; other site
709991002182	active site
709991002183	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
709991002184	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
709991002185	HD domain; Region: HD_4; pfam13328
709991002186	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
709991002187	synthetase active site [active]
709991002188	NTP binding site [chemical binding]; other site
709991002189	metal binding site [ion binding]; metal-binding site
709991002190	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
709991002191	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
709991002192	Sporulation related domain; Region: SPOR; cl10051
709991002193	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
709991002194	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
709991002195	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991002196	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
709991002197	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
709991002198	TPP-binding site [chemical binding]; other site
709991002199	dimer interface [polypeptide binding]; other site
709991002200	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
709991002201	PYR/PP interface [polypeptide binding]; other site
709991002202	dimer interface [polypeptide binding]; other site
709991002203	TPP binding site [chemical binding]; other site
709991002204	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
709991002205	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002206	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002207	probable Rubsico expression protein CbbX; Region: cbbX_cfxQ; TIGR02880
709991002208	stage V sporulation protein K; Region: spore_V_K; TIGR02881
709991002209	stage V sporulation protein K; Region: spore_V_K; TIGR02881
709991002210	Homeodomain-like domain; Region: HTH_23; pfam13384
709991002211	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
709991002212	Integrase core domain; Region: rve; pfam00665
709991002213	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
709991002214	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991002215	Walker A motif; other site
709991002216	ATP binding site [chemical binding]; other site
709991002217	Walker B motif; other site
709991002218	arginine finger; other site
709991002219	Transposase domain (DUF772); Region: DUF772; pfam05598
709991002220	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991002221	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
709991002222	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
709991002223	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
709991002224	Coenzyme A binding pocket [chemical binding]; other site
709991002225	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
709991002226	EamA-like transporter family; Region: EamA; pfam00892
709991002227	EamA-like transporter family; Region: EamA; pfam00892
709991002228	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
709991002229	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
709991002230	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
709991002231	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
709991002232	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
709991002233	active site residue [active]
709991002234	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436
709991002235	CPxP  motif; other site
709991002236	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
709991002237	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991002238	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991002239	catalytic residues [active]
709991002240	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
709991002241	dimerization interface [polypeptide binding]; other site
709991002242	putative DNA binding site [nucleotide binding]; other site
709991002243	putative Zn2+ binding site [ion binding]; other site
709991002244	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
709991002245	ribosomal protein L33; Region: rpl33; CHL00104
709991002246	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
709991002247	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
709991002248	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
709991002249	active site
709991002250	Zn binding site [ion binding]; other site
709991002251	adenylate kinase; Reviewed; Region: adk; PRK00279
709991002252	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
709991002253	AMP-binding site [chemical binding]; other site
709991002254	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
709991002255	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
709991002256	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
709991002257	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
709991002258	ligand binding site [chemical binding]; other site
709991002259	Transglycosylase; Region: Transgly; pfam00912
709991002260	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
709991002261	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
709991002262	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
709991002263	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
709991002264	ZIP Zinc transporter; Region: Zip; pfam02535
709991002265	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
709991002266	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
709991002267	ApbE family; Region: ApbE; pfam02424
709991002268	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
709991002269	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
709991002270	active site
709991002271	nucleophile elbow; other site
709991002272	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
709991002273	Surface antigen; Region: Bac_surface_Ag; pfam01103
709991002274	Response regulator receiver domain; Region: Response_reg; pfam00072
709991002275	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991002276	active site
709991002277	phosphorylation site [posttranslational modification]
709991002278	intermolecular recognition site; other site
709991002279	dimerization interface [polypeptide binding]; other site
709991002280	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991002281	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
709991002282	Walker A motif; other site
709991002283	ATP binding site [chemical binding]; other site
709991002284	Walker B motif; other site
709991002285	arginine finger; other site
709991002286	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
709991002287	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
709991002288	G1 box; other site
709991002289	GTP/Mg2+ binding site [chemical binding]; other site
709991002290	Switch I region; other site
709991002291	G2 box; other site
709991002292	Switch II region; other site
709991002293	G3 box; other site
709991002294	G4 box; other site
709991002295	Uncharacterized conserved protein [Function unknown]; Region: COG1284
709991002296	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
709991002297	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
709991002298	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
709991002299	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991002300	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991002301	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
709991002302	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
709991002303	dimer interface [polypeptide binding]; other site
709991002304	active site
709991002305	CoA binding pocket [chemical binding]; other site
709991002306	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
709991002307	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002308	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991002309	natural product precursor, GG-Bacteroidales family; Region: GG_sam_targ_CFB; TIGR04149
709991002310	GLPGLI family protein; Region: GLPGLI; TIGR01200
709991002311	radical SAM peptide maturase, GG-Bacteroidales family; Region: GG_samocin_CFB; TIGR04148
709991002312	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991002313	FeS/SAM binding site; other site
709991002314	pseudo-rSAM protein, GG-Bacteroidales system; Region: pseudo_rSAM_GG; TIGR04150
709991002315	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
709991002316	DDE superfamily endonuclease; Region: DDE_5; pfam13546
709991002317	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
709991002318	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
709991002319	putative active site [active]
709991002320	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991002321	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991002322	Walker A/P-loop; other site
709991002323	ATP binding site [chemical binding]; other site
709991002324	Q-loop/lid; other site
709991002325	ABC transporter signature motif; other site
709991002326	Walker B; other site
709991002327	D-loop; other site
709991002328	H-loop/switch region; other site
709991002329	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991002330	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991002331	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002332	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991002333	FecR protein; Region: FecR; pfam04773
709991002334	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
709991002335	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
709991002336	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002337	binding surface
709991002338	TPR motif; other site
709991002339	TPR repeat; Region: TPR_11; pfam13414
709991002340	TIR domain; Region: TIR_2; pfam13676
709991002341	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991002342	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991002343	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991002344	DNA binding residues [nucleotide binding]
709991002345	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
709991002346	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_like; cd07021
709991002347	dimer interface [polypeptide binding]; other site
709991002348	active site residues [active]
709991002349	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
709991002350	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
709991002351	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
709991002352	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
709991002353	Etoposide-induced protein 2.4 (EI24); Region: EI24; cl01126
709991002354	adenylosuccinate lyase; Provisional; Region: PRK09285
709991002355	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
709991002356	tetramer interface [polypeptide binding]; other site
709991002357	active site
709991002358	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
709991002359	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991002360	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
709991002361	Walker A/P-loop; other site
709991002362	ATP binding site [chemical binding]; other site
709991002363	Q-loop/lid; other site
709991002364	ABC transporter signature motif; other site
709991002365	Walker B; other site
709991002366	D-loop; other site
709991002367	H-loop/switch region; other site
709991002368	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
709991002369	four helix bundle protein; Region: TIGR02436
709991002370	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
709991002371	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
709991002372	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
709991002373	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
709991002374	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
709991002375	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
709991002376	protein binding site [polypeptide binding]; other site
709991002377	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
709991002378	Catalytic dyad [active]
709991002379	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
709991002380	active site
709991002381	metal binding site [ion binding]; metal-binding site
709991002382	homotetramer interface [polypeptide binding]; other site
709991002383	endonuclease IV; Provisional; Region: PRK01060
709991002384	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
709991002385	AP (apurinic/apyrimidinic) site pocket; other site
709991002386	DNA interaction; other site
709991002387	Metal-binding active site; metal-binding site
709991002388	heat shock protein 90; Provisional; Region: PRK05218
709991002389	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991002390	ATP binding site [chemical binding]; other site
709991002391	Mg2+ binding site [ion binding]; other site
709991002392	G-X-G motif; other site
709991002393	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
709991002394	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
709991002395	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
709991002396	substrate binding site [chemical binding]; other site
709991002397	ligand binding site [chemical binding]; other site
709991002398	3-isopropylmalate dehydratase small subunit; Reviewed; Region: leuD; PRK00439
709991002399	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
709991002400	substrate binding site [chemical binding]; other site
709991002401	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
709991002402	active site
709991002403	catalytic residues [active]
709991002404	metal binding site [ion binding]; metal-binding site
709991002405	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
709991002406	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991002407	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991002408	ABC transporter; Region: ABC_tran_2; pfam12848
709991002409	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991002410	LytTr DNA-binding domain; Region: LytTR; smart00850
709991002411	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
709991002412	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
709991002413	Propeptide_C25; Region: Propeptide_C25; pfam08126
709991002414	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
709991002415	active site
709991002416	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
709991002417	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
709991002418	NAD binding site [chemical binding]; other site
709991002419	substrate binding site [chemical binding]; other site
709991002420	homodimer interface [polypeptide binding]; other site
709991002421	active site
709991002422	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
709991002423	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
709991002424	NADP binding site [chemical binding]; other site
709991002425	active site
709991002426	putative substrate binding site [chemical binding]; other site
709991002427	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
709991002428	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
709991002429	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
709991002430	substrate binding site; other site
709991002431	tetramer interface; other site
709991002432	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
709991002433	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
709991002434	Mg++ binding site [ion binding]; other site
709991002435	putative catalytic motif [active]
709991002436	substrate binding site [chemical binding]; other site
709991002437	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
709991002438	NAD(P) binding site [chemical binding]; other site
709991002439	homodimer interface [polypeptide binding]; other site
709991002440	substrate binding site [chemical binding]; other site
709991002441	active site
709991002442	Bacterial sugar transferase; Region: Bac_transf; pfam02397
709991002443	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
709991002444	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
709991002445	inhibitor-cofactor binding pocket; inhibition site
709991002446	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991002447	catalytic residue [active]
709991002448	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
709991002449	active site
709991002450	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
709991002451	homodimer interface [polypeptide binding]; other site
709991002452	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
709991002453	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
709991002454	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991002455	motif II; other site
709991002456	carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767
709991002457	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
709991002458	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991002459	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
709991002460	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991002461	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
709991002462	potential frameshift: common BLAST hit: gi|150006492|ref|YP_001301236.1|  transposase
709991002463	Transposase domain (DUF772); Region: DUF772; pfam05598
709991002464	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991002465	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
709991002466	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
709991002467	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
709991002468	Ligand Binding Site [chemical binding]; other site
709991002469	Molecular Tunnel; other site
709991002470	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
709991002471	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
709991002472	Protein of unknown function (DUF3990); Region: DUF3990; pfam13151
709991002473	Protein of unknown function (DUF3791); Region: DUF3791; pfam12668
709991002474	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
709991002475	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
709991002476	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
709991002477	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
709991002478	Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132
709991002479	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
709991002480	putative trimer interface [polypeptide binding]; other site
709991002481	putative active site [active]
709991002482	putative substrate binding site [chemical binding]; other site
709991002483	putative CoA binding site [chemical binding]; other site
709991002484	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
709991002485	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
709991002486	inhibitor-cofactor binding pocket; inhibition site
709991002487	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991002488	catalytic residue [active]
709991002489	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
709991002490	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
709991002491	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
709991002492	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
709991002493	dimerization interface [polypeptide binding]; other site
709991002494	putative DNA binding site [nucleotide binding]; other site
709991002495	putative Zn2+ binding site [ion binding]; other site
709991002496	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
709991002497	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
709991002498	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
709991002499	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
709991002500	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
709991002501	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
709991002502	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
709991002503	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
709991002504	active site
709991002505	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
709991002506	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991002507	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
709991002508	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
709991002509	classical (c) SDRs; Region: SDR_c; cd05233
709991002510	NAD(P) binding site [chemical binding]; other site
709991002511	active site
709991002512	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
709991002513	classical (c) SDRs; Region: SDR_c; cd05233
709991002514	NAD(P) binding site [chemical binding]; other site
709991002515	active site
709991002516	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
709991002517	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
709991002518	active site
709991002519	CoA binding site [chemical binding]; other site
709991002520	AMP binding site [chemical binding]; other site
709991002521	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
709991002522	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
709991002523	dimer interface [polypeptide binding]; other site
709991002524	active site
709991002525	CoA binding pocket [chemical binding]; other site
709991002526	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
709991002527	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
709991002528	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
709991002529	inhibitor-cofactor binding pocket; inhibition site
709991002530	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991002531	catalytic residue [active]
709991002532	Bacterial sugar transferase; Region: Bac_transf; pfam02397
709991002533	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
709991002534	NAD(P) binding site [chemical binding]; other site
709991002535	homodimer interface [polypeptide binding]; other site
709991002536	substrate binding site [chemical binding]; other site
709991002537	active site
709991002538	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
709991002539	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
709991002540	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
709991002541	SLBB domain; Region: SLBB; pfam10531
709991002542	SLBB domain; Region: SLBB; pfam10531
709991002543	SLBB domain; Region: SLBB; pfam10531
709991002544	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
709991002545	SLBB domain; Region: SLBB; pfam10531
709991002546	Transcription antiterminator [Transcription]; Region: NusG; COG0250
709991002547	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
709991002548	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
709991002549	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
709991002550	RNA binding surface [nucleotide binding]; other site
709991002551	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
709991002552	active site
709991002553	Predicted permeases [General function prediction only]; Region: COG0795
709991002554	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
709991002555	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
709991002556	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
709991002557	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
709991002558	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991002559	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
709991002560	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
709991002561	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
709991002562	metal binding site [ion binding]; metal-binding site
709991002563	dimer interface [polypeptide binding]; other site
709991002564	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
709991002565	AMP-binding enzyme; Region: AMP-binding; pfam00501
709991002566	acyl-activating enzyme (AAE) consensus motif; other site
709991002567	putative AMP binding site [chemical binding]; other site
709991002568	putative active site [active]
709991002569	putative CoA binding site [chemical binding]; other site
709991002570	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
709991002571	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
709991002572	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
709991002573	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
709991002574	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
709991002575	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
709991002576	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cd02062
709991002577	FMN binding site [chemical binding]; other site
709991002578	dimer interface [polypeptide binding]; other site
709991002579	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
709991002580	AAA domain; Region: AAA_14; pfam13173
709991002581	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
709991002582	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
709991002583	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
709991002584	Helix-turn-helix domain; Region: HTH_17; cl17695
709991002585	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
709991002586	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
709991002587	active site
709991002588	catalytic residues [active]
709991002589	DNA binding site [nucleotide binding]
709991002590	Int/Topo IB signature motif; other site
709991002591	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
709991002592	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
709991002593	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
709991002594	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
709991002595	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
709991002596	Cl- selectivity filter; other site
709991002597	Cl- binding residues [ion binding]; other site
709991002598	pore gating glutamate residue; other site
709991002599	dimer interface [polypeptide binding]; other site
709991002600	FOG: CBS domain [General function prediction only]; Region: COG0517
709991002601	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc2; cd04613
709991002602	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
709991002603	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
709991002604	putative substrate binding site [chemical binding]; other site
709991002605	putative ATP binding site [chemical binding]; other site
709991002606	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
709991002607	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991002608	putative substrate translocation pore; other site
709991002609	POT family; Region: PTR2; cl17359
709991002610	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991002611	putative substrate translocation pore; other site
709991002612	POT family; Region: PTR2; cl17359
709991002613	Transposase domain (DUF772); Region: DUF772; pfam05598
709991002614	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991002615	Domain of unknown function (DUF4374); Region: DUF4374; pfam14298
709991002616	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002617	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991002618	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991002619	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991002620	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991002621	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991002622	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991002623	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991002624	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002625	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002626	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991002627	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002628	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991002629	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991002630	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991002631	FecR protein; Region: FecR; pfam04773
709991002632	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991002633	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991002634	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991002635	DNA binding residues [nucleotide binding]
709991002636	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991002637	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991002638	catalytic residues [active]
709991002639	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
709991002640	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991002641	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002642	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991002643	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991002644	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002645	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991002646	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991002647	FecR protein; Region: FecR; pfam04773
709991002648	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991002649	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991002650	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991002651	DNA binding residues [nucleotide binding]
709991002652	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
709991002653	Predicted membrane protein [Function unknown]; Region: COG2323
709991002654	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
709991002655	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
709991002656	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991002657	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991002658	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991002659	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991002660	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
709991002661	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
709991002662	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
709991002663	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
709991002664	active site
709991002665	catalytic site [active]
709991002666	substrate binding site [chemical binding]; other site
709991002667	DNA polymerase III subunit beta; Validated; Region: PRK05643
709991002668	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
709991002669	putative DNA binding surface [nucleotide binding]; other site
709991002670	dimer interface [polypeptide binding]; other site
709991002671	beta-clamp/translesion DNA polymerase binding surface; other site
709991002672	beta-clamp/clamp loader binding surface; other site
709991002673	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
709991002674	proline aminopeptidase P II; Provisional; Region: PRK10879
709991002675	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
709991002676	active site
709991002677	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
709991002678	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
709991002679	dimer interface [polypeptide binding]; other site
709991002680	substrate binding site [chemical binding]; other site
709991002681	metal binding site [ion binding]; metal-binding site
709991002682	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
709991002683	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
709991002684	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
709991002685	putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK05641
709991002686	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
709991002687	carboxyltransferase (CT) interaction site; other site
709991002688	biotinylation site [posttranslational modification]; other site
709991002689	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
709991002690	Uncharacterized conserved protein [Function unknown]; Region: COG3189
709991002691	peptidase T; Region: peptidase-T; TIGR01882
709991002692	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
709991002693	metal binding site [ion binding]; metal-binding site
709991002694	dimer interface [polypeptide binding]; other site
709991002695	OPT oligopeptide transporter protein; Region: OPT; pfam03169
709991002696	putative oligopeptide transporter, OPT family; Region: TIGR00733
709991002697	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
709991002698	metal ion-dependent adhesion site (MIDAS); other site
709991002699	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991002700	Walker A motif; other site
709991002701	ATP binding site [chemical binding]; other site
709991002702	Walker B motif; other site
709991002703	arginine finger; other site
709991002704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991002705	H+ Antiporter protein; Region: 2A0121; TIGR00900
709991002706	putative substrate translocation pore; other site
709991002707	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
709991002708	dimer interface [polypeptide binding]; other site
709991002709	FMN binding site [chemical binding]; other site
709991002710	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
709991002711	putative FMN binding site [chemical binding]; other site
709991002712	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
709991002713	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
709991002714	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
709991002715	ADP binding site [chemical binding]; other site
709991002716	magnesium binding site [ion binding]; other site
709991002717	putative shikimate binding site; other site
709991002718	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
709991002719	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
709991002720	CAP-like domain; other site
709991002721	active site
709991002722	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
709991002723	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991002724	ATP binding site [chemical binding]; other site
709991002725	Mg2+ binding site [ion binding]; other site
709991002726	G-X-G motif; other site
709991002727	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
709991002728	anchoring element; other site
709991002729	dimer interface [polypeptide binding]; other site
709991002730	ATP binding site [chemical binding]; other site
709991002731	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
709991002732	active site
709991002733	metal binding site [ion binding]; metal-binding site
709991002734	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
709991002735	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
709991002736	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
709991002737	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002738	TPR motif; other site
709991002739	binding surface
709991002740	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
709991002741	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
709991002742	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
709991002743	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
709991002744	ligand binding site [chemical binding]; other site
709991002745	Rubrerythrin [Energy production and conversion]; Region: COG1592
709991002746	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
709991002747	binuclear metal center [ion binding]; other site
709991002748	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
709991002749	iron binding site [ion binding]; other site
709991002750	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
709991002751	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
709991002752	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002753	binding surface
709991002754	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991002755	TPR motif; other site
709991002756	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002757	binding surface
709991002758	TPR motif; other site
709991002759	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
709991002760	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
709991002761	putative acyl-acceptor binding pocket; other site
709991002762	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991002763	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
709991002764	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
709991002765	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
709991002766	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
709991002767	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991002768	putative substrate translocation pore; other site
709991002769	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991002770	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991002771	Predicted transcriptional regulators [Transcription]; Region: COG1733
709991002772	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
709991002773	intracellular protease, PfpI family; Region: PfpI; TIGR01382
709991002774	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
709991002775	conserved cys residue [active]
709991002776	Thiamine pyrophosphokinase; Region: TPK; cd07995
709991002777	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
709991002778	active site
709991002779	dimerization interface [polypeptide binding]; other site
709991002780	thiamine binding site [chemical binding]; other site
709991002781	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
709991002782	hypothetical protein; Provisional; Region: PRK10410
709991002783	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
709991002784	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
709991002785	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
709991002786	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
709991002787	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
709991002788	ligand binding site [chemical binding]; other site
709991002789	flexible hinge region; other site
709991002790	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
709991002791	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
709991002792	ligand binding site [chemical binding]; other site
709991002793	flexible hinge region; other site
709991002794	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
709991002795	putative switch regulator; other site
709991002796	non-specific DNA interactions [nucleotide binding]; other site
709991002797	DNA binding site [nucleotide binding]
709991002798	sequence specific DNA binding site [nucleotide binding]; other site
709991002799	putative cAMP binding site [chemical binding]; other site
709991002800	4Fe-4S binding domain; Region: Fer4_6; pfam12837
709991002801	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
709991002802	hybrid cluster protein; Provisional; Region: PRK05290
709991002803	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
709991002804	ACS interaction site; other site
709991002805	CODH interaction site; other site
709991002806	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
709991002807	hybrid metal cluster; other site
709991002808	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
709991002809	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
709991002810	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991002811	TIGR04076 family protein; Region: TIGR04076
709991002812	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
709991002813	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991002814	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991002815	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
709991002816	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
709991002817	active site
709991002818	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
709991002819	nudix motif; other site
709991002820	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
709991002821	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991002822	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991002823	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991002824	catalytic residues [active]
709991002825	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991002826	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991002827	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991002828	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002829	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002830	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991002831	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991002832	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002833	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991002834	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991002835	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991002836	FecR protein; Region: FecR; pfam04773
709991002837	Protein of unknown function (DUF419); Region: DUF419; pfam04237
709991002838	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
709991002839	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
709991002840	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991002841	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991002842	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cl00200
709991002843	amphipathic channel; other site
709991002844	Asn-Pro-Ala signature motifs; other site
709991002845	peptidase T; Region: peptidase-T; TIGR01882
709991002846	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
709991002847	metal binding site [ion binding]; metal-binding site
709991002848	dimer interface [polypeptide binding]; other site
709991002849	prolyl-tRNA synthetase; Provisional; Region: PRK08661
709991002850	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
709991002851	dimer interface [polypeptide binding]; other site
709991002852	motif 1; other site
709991002853	active site
709991002854	motif 2; other site
709991002855	motif 3; other site
709991002856	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
709991002857	anticodon binding site; other site
709991002858	zinc-binding site [ion binding]; other site
709991002859	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
709991002860	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
709991002861	EamA-like transporter family; Region: EamA; cl17759
709991002862	EamA-like transporter family; Region: EamA; pfam00892
709991002863	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
709991002864	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
709991002865	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991002866	FeS/SAM binding site; other site
709991002867	TRAM domain; Region: TRAM; pfam01938
709991002868	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
709991002869	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
709991002870	dihydropteroate synthase; Region: DHPS; TIGR01496
709991002871	substrate binding pocket [chemical binding]; other site
709991002872	dimer interface [polypeptide binding]; other site
709991002873	inhibitor binding site; inhibition site
709991002874	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
709991002875	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
709991002876	Predicted membrane protein [Function unknown]; Region: COG2259
709991002877	triosephosphate isomerase; Provisional; Region: PRK14567
709991002878	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
709991002879	substrate binding site [chemical binding]; other site
709991002880	dimer interface [polypeptide binding]; other site
709991002881	catalytic triad [active]
709991002882	Peptidase family M49; Region: Peptidase_M49; pfam03571
709991002883	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
709991002884	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
709991002885	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
709991002886	dimer interface [polypeptide binding]; other site
709991002887	ADP-ribose binding site [chemical binding]; other site
709991002888	active site
709991002889	nudix motif; other site
709991002890	metal binding site [ion binding]; metal-binding site
709991002891	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
709991002892	IHF dimer interface [polypeptide binding]; other site
709991002893	IHF - DNA interface [nucleotide binding]; other site
709991002894	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
709991002895	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
709991002896	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991002897	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
709991002898	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
709991002899	putative NAD(P) binding site [chemical binding]; other site
709991002900	homodimer interface [polypeptide binding]; other site
709991002901	homotetramer interface [polypeptide binding]; other site
709991002902	active site
709991002903	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14970
709991002904	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991002905	Walker A motif; other site
709991002906	ATP binding site [chemical binding]; other site
709991002907	Walker B motif; other site
709991002908	arginine finger; other site
709991002909	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
709991002910	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991002911	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991002912	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991002913	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991002914	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
709991002915	amidase catalytic site [active]
709991002916	Zn binding residues [ion binding]; other site
709991002917	substrate binding site [chemical binding]; other site
709991002918	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
709991002919	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
709991002920	Clostripain family; Region: Peptidase_C11; pfam03415
709991002921	Part of AAA domain; Region: AAA_19; pfam13245
709991002922	Family description; Region: UvrD_C_2; pfam13538
709991002923	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991002924	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002925	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991002926	FecR protein; Region: FecR; pfam04773
709991002927	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991002928	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991002929	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991002930	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991002931	DNA binding residues [nucleotide binding]
709991002932	FecR protein; Region: FecR; pfam04773
709991002933	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991002934	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991002935	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002936	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991002937	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991002938	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991002939	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991002940	Transposase domain (DUF772); Region: DUF772; pfam05598
709991002941	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991002942	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
709991002943	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
709991002944	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991002945	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991002946	SusD family; Region: SusD; pfam07980
709991002947	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991002948	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991002949	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991002950	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991002951	FecR protein; Region: FecR; pfam04773
709991002952	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991002953	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991002954	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991002955	DNA binding residues [nucleotide binding]
709991002956	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002957	binding surface
709991002958	Tetratricopeptide repeat; Region: TPR_16; pfam13432
709991002959	TPR motif; other site
709991002960	Bacterial SH3 domain; Region: SH3_3; cl17532
709991002961	Oxygen tolerance; Region: BatD; pfam13584
709991002962	TPR repeat; Region: TPR_11; pfam13414
709991002963	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991002964	binding surface
709991002965	TPR motif; other site
709991002966	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991002967	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
709991002968	metal ion-dependent adhesion site (MIDAS); other site
709991002969	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
709991002970	hypothetical protein; Provisional; Region: PRK13685
709991002971	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
709991002972	metal ion-dependent adhesion site (MIDAS); other site
709991002973	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
709991002974	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
709991002975	metal ion-dependent adhesion site (MIDAS); other site
709991002976	MoxR-like ATPases [General function prediction only]; Region: COG0714
709991002977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991002978	Walker A motif; other site
709991002979	ATP binding site [chemical binding]; other site
709991002980	Walker B motif; other site
709991002981	arginine finger; other site
709991002982	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
709991002983	DNA-binding site [nucleotide binding]; DNA binding site
709991002984	RNA-binding motif; other site
709991002985	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
709991002986	DEAD-like helicases superfamily; Region: DEXDc; smart00487
709991002987	ATP binding site [chemical binding]; other site
709991002988	Mg++ binding site [ion binding]; other site
709991002989	motif III; other site
709991002990	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991002991	nucleotide binding region [chemical binding]; other site
709991002992	ATP-binding site [chemical binding]; other site
709991002993	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
709991002994	DPS-like protein, ferritin-like diiron-binding domain; Region: DPSL; cd01052
709991002995	Ferritin-like domain; Region: Ferritin; pfam00210
709991002996	diiron binding motif [ion binding]; other site
709991002997	Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins; Region: GDPD_SaGlpQ_like; cd08601
709991002998	Glycerophosphoryl diester phosphodiesterase family; Region: GDPD; pfam03009
709991002999	active site
709991003000	catalytic site [active]
709991003001	metal binding site [ion binding]; metal-binding site
709991003002	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
709991003003	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
709991003004	putative dimer interface [polypeptide binding]; other site
709991003005	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
709991003006	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991003007	DNA binding residues [nucleotide binding]
709991003008	dimerization interface [polypeptide binding]; other site
709991003009	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
709991003010	flavodoxin FldA; Validated; Region: PRK09267
709991003011	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991003012	Pregnancy-associated plasma protein-A; Region: Peptidase_M43; cl17409
709991003013	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
709991003014	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
709991003015	Coenzyme A binding pocket [chemical binding]; other site
709991003016	Protein of unknown function (DUF3795); Region: DUF3795; pfam12675
709991003017	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991003018	S-adenosylmethionine binding site [chemical binding]; other site
709991003019	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
709991003020	Herpesvirus BLRF2 protein; Region: Herpes_BLRF2; cl17417
709991003021	CHC2 zinc finger; Region: zf-CHC2; cl17510
709991003022	Toprim-like; Region: Toprim_2; pfam13155
709991003023	active site
709991003024	metal binding site [ion binding]; metal-binding site
709991003025	AAA domain; Region: AAA_25; pfam13481
709991003026	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
709991003027	Walker B motif; other site
709991003028	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991003029	Transposase domain (DUF772); Region: DUF772; pfam05598
709991003030	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991003031	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
709991003032	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
709991003033	putative active site [active]
709991003034	putative NTP binding site [chemical binding]; other site
709991003035	putative nucleic acid binding site [nucleotide binding]; other site
709991003036	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
709991003037	Type II intron maturase; Region: Intron_maturas2; pfam01348
709991003038	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
709991003039	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
709991003040	Glutamine amidotransferase domain; Region: GATase_6; pfam13522
709991003041	active site
709991003042	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
709991003043	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
709991003044	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
709991003045	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
709991003046	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
709991003047	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
709991003048	Active Sites [active]
709991003049	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
709991003050	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
709991003051	Walker A/P-loop; other site
709991003052	ATP binding site [chemical binding]; other site
709991003053	Q-loop/lid; other site
709991003054	ABC transporter signature motif; other site
709991003055	Walker B; other site
709991003056	D-loop; other site
709991003057	H-loop/switch region; other site
709991003058	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
709991003059	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
709991003060	dimer interface [polypeptide binding]; other site
709991003061	conserved gate region; other site
709991003062	putative PBP binding loops; other site
709991003063	ABC-ATPase subunit interface; other site
709991003064	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
709991003065	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
709991003066	dimer interface [polypeptide binding]; other site
709991003067	conserved gate region; other site
709991003068	putative PBP binding loops; other site
709991003069	ABC-ATPase subunit interface; other site
709991003070	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
709991003071	Rubredoxin [Energy production and conversion]; Region: COG1773
709991003072	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
709991003073	iron binding site [ion binding]; other site
709991003074	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
709991003075	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991003076	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991003077	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991003078	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
709991003079	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
709991003080	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
709991003081	TIGR01777 family protein; Region: yfcH
709991003082	NAD(P) binding site [chemical binding]; other site
709991003083	active site
709991003084	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
709991003085	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
709991003086	ligand binding site [chemical binding]; other site
709991003087	active site
709991003088	UGI interface [polypeptide binding]; other site
709991003089	catalytic site [active]
709991003090	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
709991003091	FAD binding domain; Region: FAD_binding_4; pfam01565
709991003092	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
709991003093	MFS transport protein AraJ; Provisional; Region: PRK10091
709991003094	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991003095	putative substrate translocation pore; other site
709991003096	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
709991003097	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
709991003098	putative metal binding site [ion binding]; other site
709991003099	Predicted acetyltransferase [General function prediction only]; Region: COG2388
709991003100	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
709991003101	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
709991003102	active site
709991003103	metal binding site [ion binding]; metal-binding site
709991003104	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
709991003105	Flavin Reductases; Region: FlaRed; cl00801
709991003106	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
709991003107	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
709991003108	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991003109	putative substrate translocation pore; other site
709991003110	Urea transporter; Region: UT; cl01829
709991003111	UreD urease accessory protein; Region: UreD; cl00530
709991003112	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
709991003113	G1 box; other site
709991003114	GTP/Mg2+ binding site [chemical binding]; other site
709991003115	G2 box; other site
709991003116	Switch I region; other site
709991003117	Switch II region; other site
709991003118	G4 box; other site
709991003119	G5 box; other site
709991003120	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
709991003121	UreF; Region: UreF; pfam01730
709991003122	urease accessory protein UreE; Provisional; Region: ureE; PRK14711
709991003123	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
709991003124	dimer interface [polypeptide binding]; other site
709991003125	catalytic residues [active]
709991003126	urease subunit alpha; Reviewed; Region: ureC; PRK13207
709991003127	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
709991003128	subunit interactions [polypeptide binding]; other site
709991003129	active site
709991003130	flap region; other site
709991003131	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
709991003132	alpha-beta subunit interface [polypeptide binding]; other site
709991003133	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
709991003134	alpha-gamma subunit interface [polypeptide binding]; other site
709991003135	beta-gamma subunit interface [polypeptide binding]; other site
709991003136	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
709991003137	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991003138	N-terminal plug; other site
709991003139	ligand-binding site [chemical binding]; other site
709991003140	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
709991003141	Metal binding protein HemV-2.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: HemV-2; cd01147
709991003142	putative metal binding site [ion binding]; other site
709991003143	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
709991003144	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
709991003145	ABC-ATPase subunit  interface; other site
709991003146	dimer interface [polypeptide binding]; other site
709991003147	putative PBP binding regions; other site
709991003148	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
709991003149	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
709991003150	Walker A/P-loop; other site
709991003151	ATP binding site [chemical binding]; other site
709991003152	Q-loop/lid; other site
709991003153	ABC transporter signature motif; other site
709991003154	Walker B; other site
709991003155	D-loop; other site
709991003156	H-loop/switch region; other site
709991003157	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
709991003158	homodimer interaction site [polypeptide binding]; other site
709991003159	cofactor binding site; other site
709991003160	FmdE, Molybdenum formylmethanofuran dehydrogenase operon; Region: FmdE; pfam02663
709991003161	Homeodomain-like domain; Region: HTH_23; pfam13384
709991003162	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
709991003163	Integrase core domain; Region: rve; pfam00665
709991003164	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
709991003165	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991003166	Walker A motif; other site
709991003167	ATP binding site [chemical binding]; other site
709991003168	Walker B motif; other site
709991003169	arginine finger; other site
709991003170	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
709991003171	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
709991003172	additional DNA contacts [nucleotide binding]; other site
709991003173	mismatch recognition site; other site
709991003174	active site
709991003175	zinc binding site [ion binding]; other site
709991003176	DNA intercalation site [nucleotide binding]; other site
709991003177	Domain of unknown function (DUF2357); Region: DUF2357; pfam09823
709991003178	Protein of unknown function (DUF524); Region: DUF524; pfam04411
709991003179	Domain of unknown function (DUF3578); Region: DUF3578; pfam12102
709991003180	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
709991003181	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
709991003182	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991003183	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991003184	ATP binding site [chemical binding]; other site
709991003185	Mg2+ binding site [ion binding]; other site
709991003186	G-X-G motif; other site
709991003187	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
709991003188	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
709991003189	cofactor binding site; other site
709991003190	DNA binding site [nucleotide binding]
709991003191	substrate interaction site [chemical binding]; other site
709991003192	Fasciclin domain; Region: Fasciclin; cl02663
709991003193	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991003194	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991003195	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991003196	non-specific DNA binding site [nucleotide binding]; other site
709991003197	salt bridge; other site
709991003198	sequence-specific DNA binding site [nucleotide binding]; other site
709991003199	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991003200	non-specific DNA binding site [nucleotide binding]; other site
709991003201	salt bridge; other site
709991003202	sequence-specific DNA binding site [nucleotide binding]; other site
709991003203	ORF6N domain; Region: ORF6N; pfam10543
709991003204	ORF6N domain; Region: ORF6N; pfam10543
709991003205	Uncharacterized conserved protein [Function unknown]; Region: COG1479
709991003206	Protein of unknown function DUF262; Region: DUF262; pfam03235
709991003207	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
709991003208	Protein of unknown function DUF262; Region: DUF262; pfam03235
709991003209	Uncharacterized conserved protein [Function unknown]; Region: COG1479
709991003210	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
709991003211	homodimer interface [polypeptide binding]; other site
709991003212	chemical substrate binding site [chemical binding]; other site
709991003213	oligomer interface [polypeptide binding]; other site
709991003214	metal binding site [ion binding]; metal-binding site
709991003215	Part of AAA domain; Region: AAA_19; pfam13245
709991003216	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
709991003217	Uncharacterized conserved protein [Function unknown]; Region: COG3410
709991003218	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
709991003219	Catalytic site [active]
709991003220	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
709991003221	active site
709991003222	NTP binding site [chemical binding]; other site
709991003223	metal binding triad [ion binding]; metal-binding site
709991003224	antibiotic binding site [chemical binding]; other site
709991003225	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
709991003226	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
709991003227	Coenzyme A binding pocket [chemical binding]; other site
709991003228	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
709991003229	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-B; cd09722
709991003230	Domain of unknown function DUF83; Region: Cas_Cas4; pfam01930
709991003231	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
709991003232	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
709991003233	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
709991003234	CRISPR-associated protein Cas5, subtype I-B/HMARI; Region: cas_Cas5h; TIGR02592
709991003235	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cl12040
709991003236	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cl01465
709991003237	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cl11443
709991003238	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
709991003239	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
709991003240	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
709991003241	active site
709991003242	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991003243	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991003244	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991003245	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
709991003246	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
709991003247	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
709991003248	Protein of unknown function, DUF479; Region: DUF479; cl01203
709991003249	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
709991003250	tyrosine decarboxylase MnfA; Region: tyr_de_CO2_Arch; TIGR03812
709991003251	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991003252	catalytic residue [active]
709991003253	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
709991003254	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
709991003255	acyl-activating enzyme (AAE) consensus motif; other site
709991003256	putative AMP binding site [chemical binding]; other site
709991003257	putative active site [active]
709991003258	putative CoA binding site [chemical binding]; other site
709991003259	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
709991003260	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
709991003261	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
709991003262	acyl-activating enzyme (AAE) consensus motif; other site
709991003263	putative AMP binding site [chemical binding]; other site
709991003264	putative active site [active]
709991003265	putative CoA binding site [chemical binding]; other site
709991003266	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
709991003267	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
709991003268	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
709991003269	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
709991003270	CAAX protease self-immunity; Region: Abi; pfam02517
709991003271	Peptidase C1-like family; Region: Peptidase_C1_2; cl17447
709991003272	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
709991003273	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
709991003274	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
709991003275	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003276	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
709991003277	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991003278	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991003279	active site
709991003280	phosphorylation site [posttranslational modification]
709991003281	intermolecular recognition site; other site
709991003282	dimerization interface [polypeptide binding]; other site
709991003283	DNA binding site [nucleotide binding]
709991003284	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
709991003285	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991003286	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991003287	ATP binding site [chemical binding]; other site
709991003288	Mg2+ binding site [ion binding]; other site
709991003289	G-X-G motif; other site
709991003290	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
709991003291	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991003292	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991003293	active site
709991003294	phosphorylation site [posttranslational modification]
709991003295	intermolecular recognition site; other site
709991003296	dimerization interface [polypeptide binding]; other site
709991003297	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
709991003298	DNA binding site [nucleotide binding]
709991003299	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991003300	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991003301	ATP binding site [chemical binding]; other site
709991003302	Mg2+ binding site [ion binding]; other site
709991003303	G-X-G motif; other site
709991003304	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
709991003305	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
709991003306	Catalytic site [active]
709991003307	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
709991003308	putative bifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta; Provisional; Region: PRK12778
709991003309	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
709991003310	FAD binding pocket [chemical binding]; other site
709991003311	FAD binding motif [chemical binding]; other site
709991003312	phosphate binding motif [ion binding]; other site
709991003313	beta-alpha-beta structure motif; other site
709991003314	NAD binding pocket [chemical binding]; other site
709991003315	Iron coordination center [ion binding]; other site
709991003316	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
709991003317	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
709991003318	putative rRNA binding site [nucleotide binding]; other site
709991003319	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991003320	FtsX-like permease family; Region: FtsX; pfam02687
709991003321	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991003322	FtsX-like permease family; Region: FtsX; pfam02687
709991003323	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991003324	FtsX-like permease family; Region: FtsX; pfam02687
709991003325	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991003326	FtsX-like permease family; Region: FtsX; pfam02687
709991003327	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991003328	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991003329	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
709991003330	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
709991003331	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991003332	active site
709991003333	phosphorylation site [posttranslational modification]
709991003334	intermolecular recognition site; other site
709991003335	dimerization interface [polypeptide binding]; other site
709991003336	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991003337	Walker A motif; other site
709991003338	ATP binding site [chemical binding]; other site
709991003339	Walker B motif; other site
709991003340	arginine finger; other site
709991003341	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
709991003342	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
709991003343	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991003344	ATP binding site [chemical binding]; other site
709991003345	Mg2+ binding site [ion binding]; other site
709991003346	G-X-G motif; other site
709991003347	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
709991003348	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
709991003349	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
709991003350	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
709991003351	generic binding surface II; other site
709991003352	generic binding surface I; other site
709991003353	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
709991003354	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
709991003355	G1 box; other site
709991003356	GTP/Mg2+ binding site [chemical binding]; other site
709991003357	Switch I region; other site
709991003358	G2 box; other site
709991003359	G3 box; other site
709991003360	Switch II region; other site
709991003361	G4 box; other site
709991003362	G5 box; other site
709991003363	RmuC family; Region: RmuC; pfam02646
709991003364	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
709991003365	DEAD-like helicases superfamily; Region: DEXDc; smart00487
709991003366	ATP binding site [chemical binding]; other site
709991003367	Mg++ binding site [ion binding]; other site
709991003368	motif III; other site
709991003369	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991003370	nucleotide binding region [chemical binding]; other site
709991003371	ATP-binding site [chemical binding]; other site
709991003372	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
709991003373	RNA binding site [nucleotide binding]; other site
709991003374	cell division protein FtsZ; Validated; Region: PRK09330
709991003375	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
709991003376	nucleotide binding site [chemical binding]; other site
709991003377	SulA interaction site; other site
709991003378	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
709991003379	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
709991003380	nucleotide binding site [chemical binding]; other site
709991003381	SulA interaction site; other site
709991003382	cell division protein FtsA; Region: ftsA; TIGR01174
709991003383	Cell division protein FtsA; Region: FtsA; smart00842
709991003384	Cell division protein FtsA; Region: FtsA; pfam14450
709991003385	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
709991003386	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
709991003387	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
709991003388	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
709991003389	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
709991003390	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
709991003391	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
709991003392	active site
709991003393	homodimer interface [polypeptide binding]; other site
709991003394	cell division protein FtsW; Region: ftsW; TIGR02614
709991003395	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
709991003396	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
709991003397	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
709991003398	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
709991003399	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
709991003400	Mg++ binding site [ion binding]; other site
709991003401	putative catalytic motif [active]
709991003402	putative substrate binding site [chemical binding]; other site
709991003403	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
709991003404	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
709991003405	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
709991003406	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
709991003407	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
709991003408	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
709991003409	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
709991003410	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
709991003411	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
709991003412	MraW methylase family; Region: Methyltransf_5; cl17771
709991003413	cell division protein MraZ; Reviewed; Region: PRK00326
709991003414	MraZ protein; Region: MraZ; pfam02381
709991003415	MraZ protein; Region: MraZ; pfam02381
709991003416	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
709991003417	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
709991003418	Int/Topo IB signature motif; other site
709991003419	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991003420	Domain of unknown function, B. Theta Gene description (DUF3876); Region: DUF3876; pfam12992
709991003421	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991003422	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991003423	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991003424	zinc transporter ZupT; Provisional; Region: PRK04201
709991003425	ZIP Zinc transporter; Region: Zip; pfam02535
709991003426	Methyltransferase domain; Region: Methyltransf_31; pfam13847
709991003427	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991003428	S-adenosylmethionine binding site [chemical binding]; other site
709991003429	Domain of unknown function (DUF1858); Region: DUF1858; cl14817
709991003430	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003431	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991003432	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991003433	Phospholipid methyltransferase; Region: PEMT; cl17370
709991003434	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
709991003435	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991003436	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991003437	Walker A/P-loop; other site
709991003438	ATP binding site [chemical binding]; other site
709991003439	Q-loop/lid; other site
709991003440	ABC transporter signature motif; other site
709991003441	Walker B; other site
709991003442	D-loop; other site
709991003443	H-loop/switch region; other site
709991003444	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
709991003445	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991003446	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991003447	Walker A/P-loop; other site
709991003448	ATP binding site [chemical binding]; other site
709991003449	Q-loop/lid; other site
709991003450	ABC transporter signature motif; other site
709991003451	Walker B; other site
709991003452	D-loop; other site
709991003453	H-loop/switch region; other site
709991003454	RteC protein; Region: RteC; pfam09357
709991003455	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
709991003456	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
709991003457	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
709991003458	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
709991003459	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
709991003460	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
709991003461	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
709991003462	SmpB-tmRNA interface; other site
709991003463	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991003464	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991003465	catalytic residues [active]
709991003466	butyryl-CoA:acetate CoA-transferase; Region: butyr_acet_CoA; TIGR03948
709991003467	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
709991003468	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
709991003469	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
709991003470	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; smart00471
709991003471	Protein of unknown function (DUF969); Region: DUF969; cl01573
709991003472	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
709991003473	Yqey-like protein; Region: YqeY; pfam09424
709991003474	mutatrotase, YjhT family; Region: muta_rot_YjhT; TIGR03547
709991003475	Surface antigen; Region: Bac_surface_Ag; pfam01103
709991003476	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_7; cd13133
709991003477	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991003478	FecR protein; Region: FecR; pfam04773
709991003479	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991003480	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003481	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
709991003482	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991003483	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991003484	homodimer interface [polypeptide binding]; other site
709991003485	catalytic residue [active]
709991003486	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
709991003487	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
709991003488	N-acetyl-D-glucosamine binding site [chemical binding]; other site
709991003489	catalytic residue [active]
709991003490	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
709991003491	Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028
709991003492	active site
709991003493	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991003494	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991003495	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991003496	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
709991003497	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
709991003498	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991003499	Domain of unknown function (DUF386); Region: DUF386; cl01047
709991003500	GTPase Era; Reviewed; Region: era; PRK00089
709991003501	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
709991003502	G1 box; other site
709991003503	GTP/Mg2+ binding site [chemical binding]; other site
709991003504	Switch I region; other site
709991003505	G2 box; other site
709991003506	Switch II region; other site
709991003507	G3 box; other site
709991003508	G4 box; other site
709991003509	G5 box; other site
709991003510	KH domain; Region: KH_2; pfam07650
709991003511	GTP-binding protein Der; Reviewed; Region: PRK00093
709991003512	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
709991003513	G1 box; other site
709991003514	GTP/Mg2+ binding site [chemical binding]; other site
709991003515	Switch I region; other site
709991003516	G2 box; other site
709991003517	Switch II region; other site
709991003518	G3 box; other site
709991003519	G4 box; other site
709991003520	G5 box; other site
709991003521	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
709991003522	G1 box; other site
709991003523	GTP/Mg2+ binding site [chemical binding]; other site
709991003524	Switch I region; other site
709991003525	G2 box; other site
709991003526	G3 box; other site
709991003527	Switch II region; other site
709991003528	G4 box; other site
709991003529	G5 box; other site
709991003530	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
709991003531	ferredoxin; Validated; Region: PRK07118
709991003532	Putative Fe-S cluster; Region: FeS; cl17515
709991003533	4Fe-4S binding domain; Region: Fer4; pfam00037
709991003534	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
709991003535	SLBB domain; Region: SLBB; pfam10531
709991003536	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
709991003537	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116
709991003538	FMN-binding domain; Region: FMN_bind; cl01081
709991003539	electron transport complex RsxE subunit; Provisional; Region: PRK12405
709991003540	electron transport complex, RnfABCDGE type, A subunit; Region: rnfA; TIGR01943
709991003541	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
709991003542	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
709991003543	active site
709991003544	NTP binding site [chemical binding]; other site
709991003545	metal binding triad [ion binding]; metal-binding site
709991003546	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
709991003547	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
709991003548	Zn2+ binding site [ion binding]; other site
709991003549	Mg2+ binding site [ion binding]; other site
709991003550	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
709991003551	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
709991003552	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
709991003553	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
709991003554	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
709991003555	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
709991003556	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
709991003557	MG2 domain; Region: A2M_N; pfam01835
709991003558	Alpha-2-macroglobulin family; Region: A2M; pfam00207
709991003559	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
709991003560	surface patch; other site
709991003561	thioester region; other site
709991003562	specificity defining residues; other site
709991003563	Divergent AAA domain; Region: AAA_4; pfam04326
709991003564	MarC family integral membrane protein; Region: MarC; cl00919
709991003565	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991003566	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991003567	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991003568	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991003569	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991003570	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
709991003571	ornithine aminotransferase; Region: Orn_aminotrans; TIGR01885
709991003572	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
709991003573	inhibitor-cofactor binding pocket; inhibition site
709991003574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991003575	catalytic residue [active]
709991003576	Family of unknown function (DUF490); Region: DUF490; pfam04357
709991003577	UGMP family protein; Validated; Region: PRK09604
709991003578	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
709991003579	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
709991003580	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
709991003581	NAD binding site [chemical binding]; other site
709991003582	Protein of unknown function, DUF399; Region: DUF399; pfam04187
709991003583	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
709991003584	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
709991003585	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
709991003586	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
709991003587	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
709991003588	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
709991003589	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003590	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
709991003591	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991003592	N-terminal plug; other site
709991003593	ligand-binding site [chemical binding]; other site
709991003594	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
709991003595	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991003596	N-terminal plug; other site
709991003597	ligand-binding site [chemical binding]; other site
709991003598	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
709991003599	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991003600	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
709991003601	nudix motif; other site
709991003602	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
709991003603	NAD binding site [chemical binding]; other site
709991003604	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
709991003605	trimer interface [polypeptide binding]; other site
709991003606	active site
709991003607	hypothetical protein; Provisional; Region: PRK01184
709991003608	Archaeal adenylate kinase [Nucleotide transport and metabolism]; Region: AdkA; cl17890
709991003609	DDE superfamily endonuclease; Region: DDE_4_2; pfam13613
709991003610	DDE superfamily endonuclease; Region: DDE_4; cl17710
709991003611	DDE superfamily endonuclease; Region: DDE_4; pfam13359
709991003612	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991003613	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991003614	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003615	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991003616	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991003617	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991003618	DDE superfamily endonuclease; Region: DDE_5; pfam13546
709991003619	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991003620	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991003621	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991003622	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991003623	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991003624	Protein of unknown function, DUF399; Region: DUF399; pfam04187
709991003625	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
709991003626	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
709991003627	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
709991003628	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
709991003629	active site
709991003630	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
709991003631	active site
709991003632	DNA polymerase IV; Validated; Region: PRK02406
709991003633	DNA binding site [nucleotide binding]
709991003634	Pirin-related protein [General function prediction only]; Region: COG1741
709991003635	Pirin; Region: Pirin; pfam02678
709991003636	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
709991003637	EamA-like transporter family; Region: EamA; pfam00892
709991003638	Tyrosine phosphatase family; Region: Y_phosphatase2; pfam03162
709991003639	AAA domain; Region: AAA_11; pfam13086
709991003640	AAA domain; Region: AAA_30; pfam13604
709991003641	AAA domain; Region: AAA_12; pfam13087
709991003642	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
709991003643	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194
709991003644	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; pfam00329
709991003645	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
709991003646	NADH dehydrogenase subunit D; Validated; Region: PRK06075
709991003647	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
709991003648	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
709991003649	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
709991003650	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
709991003651	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
709991003652	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
709991003653	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
709991003654	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
709991003655	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
709991003656	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
709991003657	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
709991003658	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
709991003659	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
709991003660	2-dehydropantoate 2-reductase; Region: apbA_panE; TIGR00745
709991003661	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
709991003662	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
709991003663	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
709991003664	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
709991003665	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991003666	motif II; other site
709991003667	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
709991003668	active site
709991003669	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991003670	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
709991003671	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
709991003672	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_7; cd13133
709991003673	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991003674	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
709991003675	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991003676	motif II; other site
709991003677	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
709991003678	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991003679	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991003680	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991003681	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
709991003682	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991003683	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991003684	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991003685	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991003686	catalytic residues [active]
709991003687	Fasciclin domain; Region: Fasciclin; cl02663
709991003688	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991003689	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991003690	SusD family; Region: SusD; pfam07980
709991003691	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991003692	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991003693	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003694	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991003695	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991003696	FecR protein; Region: FecR; pfam04773
709991003697	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991003698	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991003699	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991003700	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991003701	DNA binding residues [nucleotide binding]
709991003702	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
709991003703	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
709991003704	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
709991003705	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
709991003706	acyl-activating enzyme (AAE) consensus motif; other site
709991003707	AMP binding site [chemical binding]; other site
709991003708	active site
709991003709	CoA binding site [chemical binding]; other site
709991003710	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
709991003711	core domain interface [polypeptide binding]; other site
709991003712	delta subunit interface [polypeptide binding]; other site
709991003713	epsilon subunit interface [polypeptide binding]; other site
709991003714	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
709991003715	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
709991003716	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
709991003717	beta subunit interaction interface [polypeptide binding]; other site
709991003718	Walker A motif; other site
709991003719	ATP binding site [chemical binding]; other site
709991003720	Walker B motif; other site
709991003721	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
709991003722	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
709991003723	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
709991003724	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
709991003725	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
709991003726	ATP synthase subunit C; Region: ATP-synt_C; cl00466
709991003727	ATP synthase A chain; Region: ATP-synt_A; cl00413
709991003728	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
709991003729	gamma subunit interface [polypeptide binding]; other site
709991003730	LBP interface [polypeptide binding]; other site
709991003731	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
709991003732	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
709991003733	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
709991003734	alpha subunit interaction interface [polypeptide binding]; other site
709991003735	Walker A motif; other site
709991003736	ATP binding site [chemical binding]; other site
709991003737	Walker B motif; other site
709991003738	inhibitor binding site; inhibition site
709991003739	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
709991003740	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
709991003741	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
709991003742	ATP binding site [chemical binding]; other site
709991003743	Mg++ binding site [ion binding]; other site
709991003744	motif III; other site
709991003745	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991003746	nucleotide binding region [chemical binding]; other site
709991003747	ATP-binding site [chemical binding]; other site
709991003748	Lipocalin-like domain; Region: Lipocalin_6; pfam13944
709991003749	Lipocalin-like domain; Region: Lipocalin_6; pfam13944
709991003750	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991003751	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991003752	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
709991003753	glutaminase; Provisional; Region: PRK00971
709991003754	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
709991003755	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
709991003756	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
709991003757	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1672
709991003758	AAA ATPase domain; Region: AAA_16; pfam13191
709991003759	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
709991003760	AAA domain; Region: AAA_14; pfam13173
709991003761	Nuclease-related domain; Region: NERD; pfam08378
709991003762	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
709991003763	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
709991003764	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
709991003765	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
709991003766	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
709991003767	type II secretion system protein E; Region: type_II_gspE; TIGR02533
709991003768	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
709991003769	Walker A motif; other site
709991003770	ATP binding site [chemical binding]; other site
709991003771	Walker B motif; other site
709991003772	Type IV pilin PilA; Region: Pilin_PilA; pfam14245
709991003773	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991003774	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991003775	active site
709991003776	phosphorylation site [posttranslational modification]
709991003777	intermolecular recognition site; other site
709991003778	dimerization interface [polypeptide binding]; other site
709991003779	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
709991003780	DNA binding site [nucleotide binding]
709991003781	FecR protein; Region: FecR; pfam04773
709991003782	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991003783	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991003784	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991003785	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991003786	DNA binding residues [nucleotide binding]
709991003787	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
709991003788	Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; Region: Prefoldin; cl09111
709991003789	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
709991003790	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003791	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
709991003792	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
709991003793	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
709991003794	active site
709991003795	substrate binding site [chemical binding]; other site
709991003796	coenzyme B12 binding site [chemical binding]; other site
709991003797	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
709991003798	B12 binding site [chemical binding]; other site
709991003799	cobalt ligand [ion binding]; other site
709991003800	methylmalonyl-CoA mutase, heterodimeric type, beta chain; Region: mmCoA_mut_beta; TIGR00642
709991003801	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
709991003802	heterodimer interface [polypeptide binding]; other site
709991003803	substrate interaction site [chemical binding]; other site
709991003804	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
709991003805	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991003806	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
709991003807	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
709991003808	SCP-2 sterol transfer family; Region: SCP2; pfam02036
709991003809	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
709991003810	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991003811	motif II; other site
709991003812	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
709991003813	active site
709991003814	catalytic site [active]
709991003815	substrate binding site [chemical binding]; other site
709991003816	Predicted membrane protein [Function unknown]; Region: COG1288; cl17886
709991003817	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
709991003818	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
709991003819	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
709991003820	trimer interface [polypeptide binding]; other site
709991003821	active site
709991003822	substrate binding site [chemical binding]; other site
709991003823	CoA binding site [chemical binding]; other site
709991003824	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
709991003825	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
709991003826	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991003827	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991003828	catalytic residues [active]
709991003829	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991003830	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991003831	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991003832	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991003833	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
709991003834	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991003835	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991003836	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991003837	FecR protein; Region: FecR; pfam04773
709991003838	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991003839	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991003840	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
709991003841	DNA binding residues [nucleotide binding]
709991003842	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
709991003843	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
709991003844	Glycoprotease family; Region: Peptidase_M22; pfam00814
709991003845	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
709991003846	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
709991003847	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991003848	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991003849	catalytic residues [active]
709991003850	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991003851	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991003852	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991003853	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991003854	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003855	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991003856	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991003857	FecR protein; Region: FecR; pfam04773
709991003858	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991003859	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991003860	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
709991003861	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
709991003862	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991003863	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
709991003864	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
709991003865	ligand binding site [chemical binding]; other site
709991003866	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
709991003867	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3055
709991003868	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
709991003869	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
709991003870	active site
709991003871	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
709991003872	Transglycosylase; Region: Transgly; pfam00912
709991003873	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
709991003874	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
709991003875	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
709991003876	Cytokine receptor motif; other site
709991003877	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991003878	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991003879	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
709991003880	Low molecular weight phosphatase family; Region: LMWPc; cd00115
709991003881	active site
709991003882	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
709991003883	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
709991003884	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
709991003885	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991003886	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991003887	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003888	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991003889	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991003890	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991003891	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991003892	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991003893	FecR protein; Region: FecR; pfam04773
709991003894	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991003895	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991003896	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991003897	DNA binding residues [nucleotide binding]
709991003898	Transposase domain (DUF772); Region: DUF772; pfam05598
709991003899	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991003900	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
709991003901	Domain of unknown function DUF20; Region: UPF0118; pfam01594
709991003902	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
709991003903	nudix motif; other site
709991003904	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
709991003905	RNA polymerase sigma factor, cyanobacterial RpoD-like family; Region: Sig70-cyanoRpoD; TIGR02997
709991003906	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
709991003907	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991003908	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
709991003909	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991003910	DNA binding residues [nucleotide binding]
709991003911	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
709991003912	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
709991003913	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
709991003914	protein binding site [polypeptide binding]; other site
709991003915	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
709991003916	protein binding site [polypeptide binding]; other site
709991003917	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
709991003918	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
709991003919	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
709991003920	META domain; Region: META; pfam03724
709991003921	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
709991003922	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
709991003923	lipoyl-biotinyl attachment site [posttranslational modification]; other site
709991003924	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
709991003925	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
709991003926	FMN-binding domain; Region: FMN_bind; cl01081
709991003927	Rnf-Nqr subunit, membrane protein; Region: Rnf-Nqr; cl00597
709991003928	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
709991003929	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
709991003930	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
709991003931	catalytic loop [active]
709991003932	iron binding site [ion binding]; other site
709991003933	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
709991003934	FAD binding pocket [chemical binding]; other site
709991003935	FAD binding motif [chemical binding]; other site
709991003936	phosphate binding motif [ion binding]; other site
709991003937	beta-alpha-beta structure motif; other site
709991003938	NAD binding pocket [chemical binding]; other site
709991003939	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991003940	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991003941	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991003942	catalytic residues [active]
709991003943	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
709991003944	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991003945	SusD family; Region: SusD; pfam07980
709991003946	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991003947	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991003948	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991003949	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991003950	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991003951	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991003952	FecR protein; Region: FecR; pfam04773
709991003953	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991003954	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991003955	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991003956	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991003957	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
709991003958	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
709991003959	dimer interface [polypeptide binding]; other site
709991003960	active site
709991003961	glycine-pyridoxal phosphate binding site [chemical binding]; other site
709991003962	folate binding site [chemical binding]; other site
709991003963	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
709991003964	Beta-lactamase; Region: Beta-lactamase; pfam00144
709991003965	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
709991003966	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
709991003967	active site
709991003968	(T/H)XGH motif; other site
709991003969	pyruvate carboxylase subunit B; Validated; Region: PRK09282
709991003970	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
709991003971	active site
709991003972	catalytic residues [active]
709991003973	metal binding site [ion binding]; metal-binding site
709991003974	homodimer binding site [polypeptide binding]; other site
709991003975	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
709991003976	carboxyltransferase (CT) interaction site; other site
709991003977	biotinylation site [posttranslational modification]; other site
709991003978	potassium/proton antiporter; Reviewed; Region: PRK05326
709991003979	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
709991003980	TrkA-C domain; Region: TrkA_C; pfam02080
709991003981	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
709991003982	NlpC/P60 family; Region: NLPC_P60; pfam00877
709991003983	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991003984	catalytic residues [active]
709991003985	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991003986	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991003987	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991003988	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
709991003989	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
709991003990	Coenzyme A binding pocket [chemical binding]; other site
709991003991	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991003992	catalytic residues [active]
709991003993	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
709991003994	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
709991003995	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
709991003996	ligand binding site [chemical binding]; other site
709991003997	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
709991003998	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
709991003999	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
709991004000	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
709991004001	RNA binding surface [nucleotide binding]; other site
709991004002	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
709991004003	active site
709991004004	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
709991004005	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
709991004006	dimer interface [polypeptide binding]; other site
709991004007	active site
709991004008	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
709991004009	catalytic residues [active]
709991004010	substrate binding site [chemical binding]; other site
709991004011	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
709991004012	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
709991004013	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991004014	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991004015	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991004016	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991004017	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
709991004018	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
709991004019	Cl binding site [ion binding]; other site
709991004020	oligomer interface [polypeptide binding]; other site
709991004021	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
709991004022	putative catalytic site [active]
709991004023	putative metal binding site [ion binding]; other site
709991004024	putative phosphate binding site [ion binding]; other site
709991004025	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
709991004026	RIP metalloprotease RseP; Region: TIGR00054
709991004027	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
709991004028	active site
709991004029	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
709991004030	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
709991004031	protein binding site [polypeptide binding]; other site
709991004032	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
709991004033	putative substrate binding region [chemical binding]; other site
709991004034	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
709991004035	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
709991004036	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
709991004037	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
709991004038	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
709991004039	Peptidase family M23; Region: Peptidase_M23; pfam01551
709991004040	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
709991004041	Mechanosensitive ion channel; Region: MS_channel; pfam00924
709991004042	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991004043	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991004044	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991004045	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991004046	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991004047	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
709991004048	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991004049	putative substrate translocation pore; other site
709991004050	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
709991004051	putative ligand binding site [chemical binding]; other site
709991004052	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
709991004053	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
709991004054	G1 box; other site
709991004055	putative GEF interaction site [polypeptide binding]; other site
709991004056	GTP/Mg2+ binding site [chemical binding]; other site
709991004057	Switch I region; other site
709991004058	G2 box; other site
709991004059	G3 box; other site
709991004060	Switch II region; other site
709991004061	G4 box; other site
709991004062	G5 box; other site
709991004063	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
709991004064	Predicted thioesterase [General function prediction only]; Region: COG5496
709991004065	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
709991004066	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991004067	active site
709991004068	phosphorylation site [posttranslational modification]
709991004069	intermolecular recognition site; other site
709991004070	dimerization interface [polypeptide binding]; other site
709991004071	excinuclease ABC subunit B; Provisional; Region: PRK05298
709991004072	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991004073	ATP binding site [chemical binding]; other site
709991004074	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991004075	nucleotide binding region [chemical binding]; other site
709991004076	ATP-binding site [chemical binding]; other site
709991004077	Ultra-violet resistance protein B; Region: UvrB; pfam12344
709991004078	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
709991004079	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
709991004080	dimer interface [polypeptide binding]; other site
709991004081	active site
709991004082	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
709991004083	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
709991004084	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
709991004085	metal binding site [ion binding]; metal-binding site
709991004086	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
709991004087	active site
709991004088	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991004089	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991004090	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991004091	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991004092	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991004093	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991004094	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991004095	FecR protein; Region: FecR; pfam04773
709991004096	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991004097	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991004098	IgA Peptidase M64; Region: Peptidase_M64; pfam09471
709991004099	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991004100	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991004101	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004102	catalytic residues [active]
709991004103	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991004104	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004105	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991004106	DNA binding residues [nucleotide binding]
709991004107	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
709991004108	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
709991004109	Walker A/P-loop; other site
709991004110	ATP binding site [chemical binding]; other site
709991004111	Q-loop/lid; other site
709991004112	ABC transporter signature motif; other site
709991004113	Walker B; other site
709991004114	D-loop; other site
709991004115	H-loop/switch region; other site
709991004116	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991004117	KpsF/GutQ family protein; Region: kpsF; TIGR00393
709991004118	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
709991004119	putative active site [active]
709991004120	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
709991004121	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
709991004122	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991004123	ATP binding site [chemical binding]; other site
709991004124	putative Mg++ binding site [ion binding]; other site
709991004125	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991004126	nucleotide binding region [chemical binding]; other site
709991004127	ATP-binding site [chemical binding]; other site
709991004128	RQC domain; Region: RQC; pfam09382
709991004129	HRDC domain; Region: HRDC; pfam00570
709991004130	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
709991004131	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
709991004132	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
709991004133	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
709991004134	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
709991004135	dimer interface [polypeptide binding]; other site
709991004136	putative anticodon binding site; other site
709991004137	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
709991004138	motif 1; other site
709991004139	active site
709991004140	motif 2; other site
709991004141	motif 3; other site
709991004142	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
709991004143	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991004144	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004145	catalytic residues [active]
709991004146	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991004147	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991004148	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991004149	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004150	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991004151	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991004152	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991004153	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991004154	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991004155	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991004156	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991004157	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991004158	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991004159	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991004160	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991004161	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991004162	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991004163	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991004164	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991004165	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991004166	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
709991004167	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
709991004168	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991004169	Fic/DOC family; Region: Fic; pfam02661
709991004170	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
709991004171	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
709991004172	catalytic residues [active]
709991004173	catalytic nucleophile [active]
709991004174	Presynaptic Site I dimer interface [polypeptide binding]; other site
709991004175	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
709991004176	Synaptic Flat tetramer interface [polypeptide binding]; other site
709991004177	Synaptic Site I dimer interface [polypeptide binding]; other site
709991004178	DNA binding site [nucleotide binding]
709991004179	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
709991004180	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
709991004181	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
709991004182	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
709991004183	P-loop; other site
709991004184	Magnesium ion binding site [ion binding]; other site
709991004185	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
709991004186	Magnesium ion binding site [ion binding]; other site
709991004187	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991004188	OmpA family; Region: OmpA; pfam00691
709991004189	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
709991004190	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
709991004191	DNA binding residues [nucleotide binding]
709991004192	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991004193	AAA domain; Region: AAA_22; pfam13401
709991004194	Walker A motif; other site
709991004195	ATP binding site [chemical binding]; other site
709991004196	Walker B motif; other site
709991004197	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
709991004198	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991004199	non-specific DNA binding site [nucleotide binding]; other site
709991004200	salt bridge; other site
709991004201	sequence-specific DNA binding site [nucleotide binding]; other site
709991004202	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991004203	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
709991004204	DHH family; Region: DHH; pfam01368
709991004205	DHHA1 domain; Region: DHHA1; pfam02272
709991004206	recombination protein RecR; Reviewed; Region: recR; PRK00076
709991004207	RecR protein; Region: RecR; pfam02132
709991004208	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
709991004209	putative active site [active]
709991004210	putative metal-binding site [ion binding]; other site
709991004211	tetramer interface [polypeptide binding]; other site
709991004212	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991004213	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004214	catalytic residues [active]
709991004215	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991004216	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
709991004217	Acyltransferase family; Region: Acyl_transf_3; pfam01757
709991004218	Pregnancy-associated plasma protein-A; Region: Peptidase_M43; cl17409
709991004219	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991004220	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991004221	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991004222	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991004223	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991004224	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991004225	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
709991004226	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991004227	FecR protein; Region: FecR; pfam04773
709991004228	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
709991004229	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
709991004230	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991004231	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004232	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991004233	DNA binding residues [nucleotide binding]
709991004234	Transposase domain (DUF772); Region: DUF772; pfam05598
709991004235	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991004236	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991004237	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004238	catalytic residues [active]
709991004239	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991004240	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991004241	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004242	catalytic residues [active]
709991004243	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991004244	catalytic residues [active]
709991004245	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991004246	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004247	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991004248	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991004249	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991004250	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991004251	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991004252	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991004253	FecR protein; Region: FecR; pfam04773
709991004254	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991004255	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004256	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991004257	DNA binding residues [nucleotide binding]
709991004258	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
709991004259	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
709991004260	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
709991004261	homotrimer interaction site [polypeptide binding]; other site
709991004262	putative active site [active]
709991004263	TIGR03987 family protein; Region: TIGR03987
709991004264	Rubrerythrin [Energy production and conversion]; Region: COG1592
709991004265	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
709991004266	binuclear metal center [ion binding]; other site
709991004267	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
709991004268	iron binding site [ion binding]; other site
709991004269	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991004270	Major Facilitator Superfamily; Region: MFS_1; pfam07690
709991004271	putative substrate translocation pore; other site
709991004272	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
709991004273	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
709991004274	FMN binding site [chemical binding]; other site
709991004275	substrate binding site [chemical binding]; other site
709991004276	putative catalytic residue [active]
709991004277	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991004278	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991004279	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991004280	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991004281	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991004282	Domain of unknown function (DUF4251); Region: DUF4251; pfam14059
709991004283	Domain of unknown function (DUF4251); Region: DUF4251; pfam14059
709991004284	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
709991004285	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
709991004286	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
709991004287	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
709991004288	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
709991004289	Coenzyme A binding pocket [chemical binding]; other site
709991004290	Gram-negative bacterial tonB protein; Region: TonB; cl10048
709991004291	Thermolysin metallopeptidase, alpha-helical domain; Region: Peptidase_M4_C; pfam02868
709991004292	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991004293	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004294	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991004295	DNA binding residues [nucleotide binding]
709991004296	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
709991004297	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
709991004298	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
709991004299	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991004300	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004301	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991004302	DNA binding residues [nucleotide binding]
709991004303	FecR protein; Region: FecR; pfam04773
709991004304	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991004305	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991004306	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004307	catalytic residues [active]
709991004308	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991004309	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991004310	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991004311	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991004312	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991004313	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991004314	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
709991004315	active site
709991004316	catalytic residues [active]
709991004317	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
709991004318	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991004319	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991004320	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004321	catalytic residues [active]
709991004322	putative transporter; Validated; Region: PRK03818
709991004323	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
709991004324	TrkA-C domain; Region: TrkA_C; pfam02080
709991004325	TrkA-C domain; Region: TrkA_C; pfam02080
709991004326	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
709991004327	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
709991004328	Peptidase family M23; Region: Peptidase_M23; pfam01551
709991004329	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
709991004330	active site
709991004331	catalytic motif [active]
709991004332	Zn binding site [ion binding]; other site
709991004333	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
709991004334	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
709991004335	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
709991004336	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
709991004337	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
709991004338	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
709991004339	Ligand binding site; other site
709991004340	Putative Catalytic site; other site
709991004341	DXD motif; other site
709991004342	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
709991004343	putative active site [active]
709991004344	POT family; Region: PTR2; cl17359
709991004345	POT family; Region: PTR2; cl17359
709991004346	pyruvate dehydrogenase; Provisional; Region: PRK06546
709991004347	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
709991004348	PYR/PP interface [polypeptide binding]; other site
709991004349	tetramer interface [polypeptide binding]; other site
709991004350	dimer interface [polypeptide binding]; other site
709991004351	TPP binding site [chemical binding]; other site
709991004352	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
709991004353	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
709991004354	TPP-binding site [chemical binding]; other site
709991004355	polyphosphate kinase 1; Region: poly_P_kin; TIGR03705
709991004356	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
709991004357	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
709991004358	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
709991004359	domain interface [polypeptide binding]; other site
709991004360	active site
709991004361	catalytic site [active]
709991004362	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
709991004363	putative active site [active]
709991004364	catalytic site [active]
709991004365	exopolyphosphatase; Region: exo_poly_only; TIGR03706
709991004366	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
709991004367	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
709991004368	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
709991004369	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
709991004370	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
709991004371	carboxyltransferase (CT) interaction site; other site
709991004372	biotinylation site [posttranslational modification]; other site
709991004373	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991004374	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
709991004375	Walker A/P-loop; other site
709991004376	ATP binding site [chemical binding]; other site
709991004377	Q-loop/lid; other site
709991004378	ABC transporter signature motif; other site
709991004379	Walker B; other site
709991004380	D-loop; other site
709991004381	H-loop/switch region; other site
709991004382	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
709991004383	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
709991004384	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
709991004385	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004386	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991004387	DNA binding residues [nucleotide binding]
709991004388	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
709991004389	Uncharacterized conserved protein [Function unknown]; Region: COG4198
709991004390	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
709991004391	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
709991004392	putative ligand binding site [chemical binding]; other site
709991004393	putative NAD binding site [chemical binding]; other site
709991004394	putative catalytic site [active]
709991004395	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
709991004396	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991004397	catalytic residue [active]
709991004398	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
709991004399	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
709991004400	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
709991004401	anti sigma factor interaction site; other site
709991004402	regulatory phosphorylation site [posttranslational modification]; other site
709991004403	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991004404	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991004405	active site
709991004406	phosphorylation site [posttranslational modification]
709991004407	intermolecular recognition site; other site
709991004408	dimerization interface [polypeptide binding]; other site
709991004409	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
709991004410	DNA binding site [nucleotide binding]
709991004411	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991004412	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991004413	dimer interface [polypeptide binding]; other site
709991004414	phosphorylation site [posttranslational modification]
709991004415	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991004416	ATP binding site [chemical binding]; other site
709991004417	Mg2+ binding site [ion binding]; other site
709991004418	G-X-G motif; other site
709991004419	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991004420	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991004421	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991004422	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991004423	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991004424	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991004425	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991004426	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
709991004427	active site
709991004428	motif I; other site
709991004429	motif II; other site
709991004430	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991004431	pyruvate kinase; Provisional; Region: PRK05826
709991004432	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
709991004433	domain interfaces; other site
709991004434	active site
709991004435	Dehydroquinase class II; Region: DHquinase_II; pfam01220
709991004436	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
709991004437	active site
709991004438	trimer interface [polypeptide binding]; other site
709991004439	dimer interface [polypeptide binding]; other site
709991004440	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
709991004441	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
709991004442	active site
709991004443	Int/Topo IB signature motif; other site
709991004444	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
709991004445	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
709991004446	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
709991004447	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
709991004448	Transposase domain (DUF772); Region: DUF772; pfam05598
709991004449	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991004450	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
709991004451	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991004452	non-specific DNA binding site [nucleotide binding]; other site
709991004453	salt bridge; other site
709991004454	sequence-specific DNA binding site [nucleotide binding]; other site
709991004455	HipA N-terminal domain; Region: Couple_hipA; pfam13657
709991004456	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
709991004457	HipA-like N-terminal domain; Region: HipA_N; pfam07805
709991004458	HipA-like C-terminal domain; Region: HipA_C; pfam07804
709991004459	Microscilla MS158 and related proteins, metallophosphatase domain; Region: MPP_MS158; cd07404
709991004460	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
709991004461	putative active site [active]
709991004462	putative metal binding site [ion binding]; other site
709991004463	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
709991004464	Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain; Region: MPP_AQ1575; cd07390
709991004465	putative active site [active]
709991004466	putative metal binding site [ion binding]; other site
709991004467	Archaeal ATPase; Region: Arch_ATPase; pfam01637
709991004468	AAA domain; Region: AAA_14; pfam13173
709991004469	Archaea bacterial proteins of unknown function; Region: DUF234; pfam03008
709991004470	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991004471	non-specific DNA binding site [nucleotide binding]; other site
709991004472	salt bridge; other site
709991004473	sequence-specific DNA binding site [nucleotide binding]; other site
709991004474	LlaJI restriction endonuclease; Region: RE_LlaJI; pfam09563
709991004475	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991004476	AAA domain; Region: AAA_21; pfam13304
709991004477	Walker A/P-loop; other site
709991004478	ATP binding site [chemical binding]; other site
709991004479	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991004480	ABC transporter signature motif; other site
709991004481	Walker B; other site
709991004482	D-loop; other site
709991004483	H-loop/switch region; other site
709991004484	Cytidylyltransferase family; Region: CTP_transf_1; cl17467
709991004485	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
709991004486	Domain of unknown function DUF87; Region: DUF87; pfam01935
709991004487	HerA helicase [Replication, recombination, and repair]; Region: COG0433
709991004488	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
709991004489	additional DNA contacts [nucleotide binding]; other site
709991004490	mismatch recognition site; other site
709991004491	active site
709991004492	zinc binding site [ion binding]; other site
709991004493	DNA intercalation site [nucleotide binding]; other site
709991004494	Virulence protein [General function prediction only]; Region: COG3943
709991004495	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
709991004496	Virulence protein [General function prediction only]; Region: COG3943
709991004497	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
709991004498	AAA domain; Region: AAA_25; pfam13481
709991004499	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991004500	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
709991004501	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
709991004502	Int/Topo IB signature motif; other site
709991004503	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991004504	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991004505	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
709991004506	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
709991004507	trmE is a tRNA modification GTPase; Region: trmE; cd04164
709991004508	G1 box; other site
709991004509	GTP/Mg2+ binding site [chemical binding]; other site
709991004510	Switch I region; other site
709991004511	G2 box; other site
709991004512	Switch II region; other site
709991004513	G3 box; other site
709991004514	G4 box; other site
709991004515	G5 box; other site
709991004516	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
709991004517	Domain of unknown function (DUF4251); Region: DUF4251; pfam14059
709991004518	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
709991004519	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
709991004520	substrate binding site [chemical binding]; other site
709991004521	tetramer interface [polypeptide binding]; other site
709991004522	catalytic residue [active]
709991004523	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
709991004524	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
709991004525	ATP binding site [chemical binding]; other site
709991004526	Mg++ binding site [ion binding]; other site
709991004527	motif III; other site
709991004528	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991004529	nucleotide binding region [chemical binding]; other site
709991004530	ATP-binding site [chemical binding]; other site
709991004531	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
709991004532	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
709991004533	putative active site [active]
709991004534	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
709991004535	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
709991004536	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
709991004537	putative RNA binding site [nucleotide binding]; other site
709991004538	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991004539	S-adenosylmethionine binding site [chemical binding]; other site
709991004540	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
709991004541	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
709991004542	active site
709991004543	substrate binding site [chemical binding]; other site
709991004544	metal binding site [ion binding]; metal-binding site
709991004545	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
709991004546	lipoyl attachment site [posttranslational modification]; other site
709991004547	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_7; cd13133
709991004548	putative efflux protein, MATE family; Region: matE; TIGR00797
709991004549	ornithine carbamoyltransferase; Validated; Region: PRK02102
709991004550	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
709991004551	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
709991004552	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
709991004553	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
709991004554	putative substrate binding site [chemical binding]; other site
709991004555	nucleotide binding site [chemical binding]; other site
709991004556	nucleotide binding site [chemical binding]; other site
709991004557	homodimer interface [polypeptide binding]; other site
709991004558	Septum formation initiator; Region: DivIC; pfam04977
709991004559	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
709991004560	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
709991004561	active site
709991004562	catalytic residues [active]
709991004563	metal binding site [ion binding]; metal-binding site
709991004564	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
709991004565	Competence protein; Region: Competence; pfam03772
709991004566	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
709991004567	TrkA-N domain; Region: TrkA_N; pfam02254
709991004568	TrkA-C domain; Region: TrkA_C; pfam02080
709991004569	TrkA-N domain; Region: TrkA_N; pfam02254
709991004570	TrkA-C domain; Region: TrkA_C; pfam02080
709991004571	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
709991004572	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
709991004573	MgtC family; Region: MgtC; pfam02308
709991004574	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
709991004575	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
709991004576	active site
709991004577	intersubunit interactions; other site
709991004578	catalytic residue [active]
709991004579	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
709991004580	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991004581	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991004582	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004583	catalytic residues [active]
709991004584	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991004585	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991004586	FecR protein; Region: FecR; pfam04773
709991004587	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
709991004588	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
709991004589	dimer interface [polypeptide binding]; other site
709991004590	motif 1; other site
709991004591	active site
709991004592	motif 2; other site
709991004593	motif 3; other site
709991004594	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
709991004595	anticodon binding site; other site
709991004596	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
709991004597	active sites [active]
709991004598	tetramer interface [polypeptide binding]; other site
709991004599	MG2 domain; Region: A2M_N; pfam01835
709991004600	Alpha-2-macroglobulin family; Region: A2M; pfam00207
709991004601	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
709991004602	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
709991004603	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991004604	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991004605	active site
709991004606	phosphorylation site [posttranslational modification]
709991004607	intermolecular recognition site; other site
709991004608	dimerization interface [polypeptide binding]; other site
709991004609	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
709991004610	DNA binding site [nucleotide binding]
709991004611	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991004612	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991004613	dimer interface [polypeptide binding]; other site
709991004614	phosphorylation site [posttranslational modification]
709991004615	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991004616	ATP binding site [chemical binding]; other site
709991004617	Mg2+ binding site [ion binding]; other site
709991004618	G-X-G motif; other site
709991004619	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991004620	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991004621	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991004622	catalytic residues [active]
709991004623	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991004624	TPR motif; other site
709991004625	binding surface
709991004626	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
709991004627	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
709991004628	motif 1; other site
709991004629	active site
709991004630	motif 2; other site
709991004631	motif 3; other site
709991004632	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
709991004633	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
709991004634	Peptidase family M23; Region: Peptidase_M23; pfam01551
709991004635	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
709991004636	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
709991004637	DNA binding residues [nucleotide binding]
709991004638	Uncharacterized conserved protein [Function unknown]; Region: COG0327
709991004639	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
709991004640	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
709991004641	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
709991004642	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
709991004643	Putative zinc ribbon domain; Region: DUF164; pfam02591
709991004644	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
709991004645	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991004646	active site
709991004647	HIGH motif; other site
709991004648	nucleotide binding site [chemical binding]; other site
709991004649	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
709991004650	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
709991004651	active site
709991004652	KMSKS motif; other site
709991004653	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
709991004654	tRNA binding surface [nucleotide binding]; other site
709991004655	anticodon binding site; other site
709991004656	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
709991004657	Transposase domain (DUF772); Region: DUF772; pfam05598
709991004658	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991004659	HipA N-terminal domain; Region: Couple_hipA; pfam13657
709991004660	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
709991004661	HipA-like N-terminal domain; Region: HipA_N; pfam07805
709991004662	HipA-like C-terminal domain; Region: HipA_C; pfam07804
709991004663	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991004664	non-specific DNA binding site [nucleotide binding]; other site
709991004665	salt bridge; other site
709991004666	sequence-specific DNA binding site [nucleotide binding]; other site
709991004667	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
709991004668	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991004669	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991004670	SusD family; Region: SusD; pfam07980
709991004671	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991004672	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991004673	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991004674	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991004675	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991004676	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991004677	FecR protein; Region: FecR; pfam04773
709991004678	Divergent AAA domain; Region: AAA_4; pfam04326
709991004679	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
709991004680	WYL domain; Region: WYL; cl14852
709991004681	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
709991004682	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
709991004683	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
709991004684	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
709991004685	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991004686	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991004687	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991004688	DNA binding residues [nucleotide binding]
709991004689	NAD-dependent deacetylase; Provisional; Region: PRK00481
709991004690	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
709991004691	NAD+ binding site [chemical binding]; other site
709991004692	substrate binding site [chemical binding]; other site
709991004693	Zn binding site [ion binding]; other site
709991004694	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
709991004695	TRAM domain; Region: TRAM; pfam01938
709991004696	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991004697	S-adenosylmethionine binding site [chemical binding]; other site
709991004698	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
709991004699	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
709991004700	dimerization interface [polypeptide binding]; other site
709991004701	DPS ferroxidase diiron center [ion binding]; other site
709991004702	ion pore; other site
709991004703	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
709991004704	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991004705	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
709991004706	A new structural DNA glycosylase; Region: AlkD_like; cl11434
709991004707	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
709991004708	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
709991004709	active site
709991004710	substrate-binding site [chemical binding]; other site
709991004711	metal-binding site [ion binding]
709991004712	ATP binding site [chemical binding]; other site
709991004713	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
709991004714	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
709991004715	active site
709991004716	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
709991004717	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
709991004718	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
709991004719	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
709991004720	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
709991004721	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
709991004722	trimer interface [polypeptide binding]; other site
709991004723	active site
709991004724	UDP-GlcNAc binding site [chemical binding]; other site
709991004725	lipid binding site [chemical binding]; lipid-binding site
709991004726	ribosome maturation protein RimP; Reviewed; Region: PRK00092
709991004727	Sm and related proteins; Region: Sm_like; cl00259
709991004728	transcription termination factor NusA; Region: NusA; TIGR01953
709991004729	NusA N-terminal domain; Region: NusA_N; pfam08529
709991004730	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
709991004731	RNA binding site [nucleotide binding]; other site
709991004732	homodimer interface [polypeptide binding]; other site
709991004733	NusA-like KH domain; Region: KH_5; pfam13184
709991004734	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
709991004735	G-X-X-G motif; other site
709991004736	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
709991004737	translation initiation factor IF-2; Region: IF-2; TIGR00487
709991004738	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
709991004739	G1 box; other site
709991004740	putative GEF interaction site [polypeptide binding]; other site
709991004741	GTP/Mg2+ binding site [chemical binding]; other site
709991004742	Switch I region; other site
709991004743	G2 box; other site
709991004744	G3 box; other site
709991004745	Switch II region; other site
709991004746	G4 box; other site
709991004747	G5 box; other site
709991004748	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
709991004749	Translation-initiation factor 2; Region: IF-2; pfam11987
709991004750	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
709991004751	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
709991004752	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
709991004753	putative active site [active]
709991004754	putative metal binding site [ion binding]; other site
709991004755	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
709991004756	active site
709991004757	dimer interfaces [polypeptide binding]; other site
709991004758	catalytic residues [active]
709991004759	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991004760	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991004761	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
709991004762	Protein export membrane protein; Region: SecD_SecF; cl14618
709991004763	Outer membrane efflux protein; Region: OEP; pfam02321
709991004764	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
709991004765	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991004766	motif II; other site
709991004767	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
709991004768	CoenzymeA binding site [chemical binding]; other site
709991004769	subunit interaction site [polypeptide binding]; other site
709991004770	PHB binding site; other site
709991004771	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
709991004772	DNA-binding site [nucleotide binding]; DNA binding site
709991004773	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
709991004774	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991004775	Walker A/P-loop; other site
709991004776	ATP binding site [chemical binding]; other site
709991004777	Q-loop/lid; other site
709991004778	ABC transporter signature motif; other site
709991004779	Walker B; other site
709991004780	D-loop; other site
709991004781	H-loop/switch region; other site
709991004782	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
709991004783	nucleotide binding site/active site [active]
709991004784	HIT family signature motif; other site
709991004785	catalytic residue [active]
709991004786	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
709991004787	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
709991004788	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
709991004789	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
709991004790	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
709991004791	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
709991004792	active site
709991004793	substrate binding site [chemical binding]; other site
709991004794	metal binding site [ion binding]; metal-binding site
709991004795	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991004796	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
709991004797	Walker A motif; other site
709991004798	ATP binding site [chemical binding]; other site
709991004799	Walker B motif; other site
709991004800	arginine finger; other site
709991004801	Family description; Region: UvrD_C_2; pfam13538
709991004802	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
709991004803	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
709991004804	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991004805	S-adenosylmethionine binding site [chemical binding]; other site
709991004806	glycine dehydrogenase; Provisional; Region: PRK05367
709991004807	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
709991004808	tetramer interface [polypeptide binding]; other site
709991004809	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991004810	catalytic residue [active]
709991004811	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
709991004812	tetramer interface [polypeptide binding]; other site
709991004813	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991004814	catalytic residue [active]
709991004815	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
709991004816	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.   The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_5; cd06153
709991004817	homotrimer interaction site [polypeptide binding]; other site
709991004818	putative active site [active]
709991004819	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
709991004820	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991004821	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
709991004822	Walker A/P-loop; other site
709991004823	ATP binding site [chemical binding]; other site
709991004824	Q-loop/lid; other site
709991004825	ABC transporter signature motif; other site
709991004826	Walker B; other site
709991004827	D-loop; other site
709991004828	H-loop/switch region; other site
709991004829	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
709991004830	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
709991004831	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991004832	Walker A/P-loop; other site
709991004833	ATP binding site [chemical binding]; other site
709991004834	Q-loop/lid; other site
709991004835	ABC transporter signature motif; other site
709991004836	Walker B; other site
709991004837	D-loop; other site
709991004838	H-loop/switch region; other site
709991004839	V-type ATP synthase subunit K; Provisional; Region: PRK09621
709991004840	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
709991004841	V-type ATP synthase subunit I; Validated; Region: PRK05771
709991004842	ATP synthase subunit D; Region: ATP-synt_D; cl00613
709991004843	V-type ATP synthase subunit B; Provisional; Region: PRK02118
709991004844	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
709991004845	Walker A motif homologous position; other site
709991004846	Walker B motif; other site
709991004847	V-type ATP synthase subunit A; Provisional; Region: PRK04192
709991004848	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
709991004849	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
709991004850	Walker A motif/ATP binding site; other site
709991004851	Walker B motif; other site
709991004852	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
709991004853	V-type ATP synthase subunit E; Provisional; Region: PRK01558
709991004854	TIR domain; Region: TIR_2; pfam13676
709991004855	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
709991004856	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
709991004857	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
709991004858	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
709991004859	Domain of unknown function (DUF3332); Region: DUF3332; pfam11810
709991004860	Predicted membrane protein [Function unknown]; Region: COG2855
709991004861	ParB-like nuclease domain; Region: ParBc; cl02129
709991004862	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
709991004863	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
709991004864	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
709991004865	Active Sites [active]
709991004866	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
709991004867	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
709991004868	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
709991004869	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
709991004870	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
709991004871	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991004872	Walker A/P-loop; other site
709991004873	ATP binding site [chemical binding]; other site
709991004874	Q-loop/lid; other site
709991004875	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991004876	ABC transporter signature motif; other site
709991004877	Walker B; other site
709991004878	D-loop; other site
709991004879	ABC transporter; Region: ABC_tran_2; pfam12848
709991004880	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991004881	Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; Region: ALDH_F4-17_P5CDH; cd07123
709991004882	delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Region: D1pyr5carbox1; TIGR01236
709991004883	Glutamate binding site [chemical binding]; other site
709991004884	NAD binding site [chemical binding]; other site
709991004885	catalytic residues [active]
709991004886	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
709991004887	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
709991004888	Domain of unknown function (DUF389); Region: DUF389; pfam04087
709991004889	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
709991004890	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
709991004891	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
709991004892	generic binding surface II; other site
709991004893	ssDNA binding site; other site
709991004894	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991004895	ATP binding site [chemical binding]; other site
709991004896	putative Mg++ binding site [ion binding]; other site
709991004897	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991004898	nucleotide binding region [chemical binding]; other site
709991004899	ATP-binding site [chemical binding]; other site
709991004900	Domain of unknown function (DUF3332); Region: DUF3332; pfam11810
709991004901	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
709991004902	Aspartase; Region: Aspartase; cd01357
709991004903	active sites [active]
709991004904	tetramer interface [polypeptide binding]; other site
709991004905	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
709991004906	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
709991004907	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
709991004908	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
709991004909	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
709991004910	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
709991004911	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
709991004912	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
709991004913	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
709991004914	Apocytochrome F, C-terminal; Region: Apocytochr_F_C; cl03168
709991004915	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
709991004916	DNA binding site [nucleotide binding]
709991004917	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
709991004918	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
709991004919	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
709991004920	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
709991004921	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
709991004922	RPB11 interaction site [polypeptide binding]; other site
709991004923	RPB12 interaction site [polypeptide binding]; other site
709991004924	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
709991004925	RPB3 interaction site [polypeptide binding]; other site
709991004926	RPB1 interaction site [polypeptide binding]; other site
709991004927	RPB11 interaction site [polypeptide binding]; other site
709991004928	RPB10 interaction site [polypeptide binding]; other site
709991004929	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
709991004930	core dimer interface [polypeptide binding]; other site
709991004931	peripheral dimer interface [polypeptide binding]; other site
709991004932	L10 interface [polypeptide binding]; other site
709991004933	L11 interface [polypeptide binding]; other site
709991004934	putative EF-Tu interaction site [polypeptide binding]; other site
709991004935	putative EF-G interaction site [polypeptide binding]; other site
709991004936	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
709991004937	23S rRNA interface [nucleotide binding]; other site
709991004938	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
709991004939	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
709991004940	mRNA/rRNA interface [nucleotide binding]; other site
709991004941	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
709991004942	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
709991004943	23S rRNA interface [nucleotide binding]; other site
709991004944	L7/L12 interface [polypeptide binding]; other site
709991004945	putative thiostrepton binding site; other site
709991004946	L25 interface [polypeptide binding]; other site
709991004947	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
709991004948	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
709991004949	putative homodimer interface [polypeptide binding]; other site
709991004950	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
709991004951	heterodimer interface [polypeptide binding]; other site
709991004952	homodimer interface [polypeptide binding]; other site
709991004953	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
709991004954	elongation factor Tu; Reviewed; Region: PRK12735
709991004955	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
709991004956	G1 box; other site
709991004957	GEF interaction site [polypeptide binding]; other site
709991004958	GTP/Mg2+ binding site [chemical binding]; other site
709991004959	Switch I region; other site
709991004960	G2 box; other site
709991004961	G3 box; other site
709991004962	Switch II region; other site
709991004963	G4 box; other site
709991004964	G5 box; other site
709991004965	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
709991004966	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
709991004967	Antibiotic Binding Site [chemical binding]; other site
709991004968	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cl00250
709991004969	30S subunit binding site; other site
709991004970	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
709991004971	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
709991004972	active site
709991004973	DNA binding site [nucleotide binding]
709991004974	Int/Topo IB signature motif; other site
709991004975	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
709991004976	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
709991004977	TrkA-N domain; Region: TrkA_N; pfam02254
709991004978	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
709991004979	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
709991004980	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
709991004981	Peptidase family M23; Region: Peptidase_M23; pfam01551
709991004982	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
709991004983	proteasome-activating nucleotidase; Provisional; Region: PRK03992
709991004984	Cell division protein ZapA; Region: ZapA; cl01146
709991004985	phosphodiesterase; Provisional; Region: PRK12704
709991004986	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
709991004987	Zn2+ binding site [ion binding]; other site
709991004988	Mg2+ binding site [ion binding]; other site
709991004989	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
709991004990	Mechanosensitive ion channel; Region: MS_channel; pfam00924
709991004991	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991004992	Protein export membrane protein; Region: SecD_SecF; cl14618
709991004993	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991004994	Protein export membrane protein; Region: SecD_SecF; cl14618
709991004995	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991004996	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991004997	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991004998	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
709991004999	O-Antigen ligase; Region: Wzy_C; pfam04932
709991005000	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991005001	TPR motif; other site
709991005002	binding surface
709991005003	TPR repeat; Region: TPR_11; pfam13414
709991005004	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991005005	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005006	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991005007	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991005008	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991005009	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991005010	SusD family; Region: SusD; pfam07980
709991005011	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991005012	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991005013	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991005014	ATP binding site [chemical binding]; other site
709991005015	G-X-G motif; other site
709991005016	Response regulator receiver domain; Region: Response_reg; pfam00072
709991005017	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991005018	active site
709991005019	phosphorylation site [posttranslational modification]
709991005020	intermolecular recognition site; other site
709991005021	dimerization interface [polypeptide binding]; other site
709991005022	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
709991005023	conserved cys residue [active]
709991005024	Predicted transcriptional regulator [Transcription]; Region: COG2378
709991005025	HTH domain; Region: HTH_11; pfam08279
709991005026	WYL domain; Region: WYL; pfam13280
709991005027	Helix-turn-helix domain; Region: HTH_17; cl17695
709991005028	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
709991005029	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
709991005030	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
709991005031	active site
709991005032	metal binding site [ion binding]; metal-binding site
709991005033	interdomain interaction site; other site
709991005034	Virulence-associated protein E; Region: VirE; pfam05272
709991005035	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991005036	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991005037	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991005038	SEFIR domain; Region: SEFIR; pfam08357
709991005039	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
709991005040	Int/Topo IB signature motif; other site
709991005041	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
709991005042	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
709991005043	Peptidase family C69; Region: Peptidase_C69; cl17793
709991005044	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
709991005045	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
709991005046	Ligand Binding Site [chemical binding]; other site
709991005047	PBP superfamily domain; Region: PBP_like_2; cl17296
709991005048	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
709991005049	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
709991005050	dimer interface [polypeptide binding]; other site
709991005051	conserved gate region; other site
709991005052	putative PBP binding loops; other site
709991005053	ABC-ATPase subunit interface; other site
709991005054	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
709991005055	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
709991005056	dimer interface [polypeptide binding]; other site
709991005057	conserved gate region; other site
709991005058	putative PBP binding loops; other site
709991005059	ABC-ATPase subunit interface; other site
709991005060	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
709991005061	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
709991005062	Walker A/P-loop; other site
709991005063	ATP binding site [chemical binding]; other site
709991005064	Q-loop/lid; other site
709991005065	ABC transporter signature motif; other site
709991005066	Walker B; other site
709991005067	D-loop; other site
709991005068	H-loop/switch region; other site
709991005069	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
709991005070	PhoU domain; Region: PhoU; pfam01895
709991005071	PhoU domain; Region: PhoU; pfam01895
709991005072	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991005073	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991005074	active site
709991005075	phosphorylation site [posttranslational modification]
709991005076	intermolecular recognition site; other site
709991005077	dimerization interface [polypeptide binding]; other site
709991005078	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
709991005079	DNA binding site [nucleotide binding]
709991005080	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991005081	dimer interface [polypeptide binding]; other site
709991005082	phosphorylation site [posttranslational modification]
709991005083	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991005084	ATP binding site [chemical binding]; other site
709991005085	Mg2+ binding site [ion binding]; other site
709991005086	G-X-G motif; other site
709991005087	NigD-like protein; Region: NigD; pfam12667
709991005088	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
709991005089	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
709991005090	active site
709991005091	DNA binding site [nucleotide binding]
709991005092	Int/Topo IB signature motif; other site
709991005093	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
709991005094	ATP binding site [chemical binding]; other site
709991005095	putative Mg++ binding site [ion binding]; other site
709991005096	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
709991005097	MPN+ (JAMM) motif; other site
709991005098	Zinc-binding site [ion binding]; other site
709991005099	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
709991005100	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991005101	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991005102	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991005103	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991005104	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
709991005105	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
709991005106	Substrate binding site [chemical binding]; other site
709991005107	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
709991005108	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
709991005109	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
709991005110	4Fe-4S binding domain; Region: Fer4_6; pfam12837
709991005111	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
709991005112	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
709991005113	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991005114	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
709991005115	PQQ-like domain; Region: PQQ_2; pfam13360
709991005116	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
709991005117	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
709991005118	Walker A/P-loop; other site
709991005119	ATP binding site [chemical binding]; other site
709991005120	Q-loop/lid; other site
709991005121	ABC transporter signature motif; other site
709991005122	Walker B; other site
709991005123	D-loop; other site
709991005124	H-loop/switch region; other site
709991005125	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
709991005126	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
709991005127	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
709991005128	ABC-ATPase subunit  interface; other site
709991005129	dimer interface [polypeptide binding]; other site
709991005130	putative PBP binding regions; other site
709991005131	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
709991005132	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
709991005133	putative ligand binding site [chemical binding]; other site
709991005134	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
709991005135	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
709991005136	homodimer interface [polypeptide binding]; other site
709991005137	Walker A motif; other site
709991005138	ATP binding site [chemical binding]; other site
709991005139	hydroxycobalamin binding site [chemical binding]; other site
709991005140	Walker B motif; other site
709991005141	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
709991005142	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
709991005143	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
709991005144	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
709991005145	Ligand binding site [chemical binding]; other site
709991005146	Electron transfer flavoprotein domain; Region: ETF; pfam01012
709991005147	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
709991005148	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
709991005149	FAD binding site [chemical binding]; other site
709991005150	homotetramer interface [polypeptide binding]; other site
709991005151	substrate binding pocket [chemical binding]; other site
709991005152	catalytic base [active]
709991005153	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
709991005154	substrate binding site [chemical binding]; other site
709991005155	THF binding site; other site
709991005156	zinc-binding site [ion binding]; other site
709991005157	Predicted metal-binding protein (DUF2284); Region: DUF2284; cl02248
709991005158	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
709991005159	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
709991005160	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
709991005161	putative catalytic cysteine [active]
709991005162	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
709991005163	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
709991005164	active site
709991005165	NAD binding site [chemical binding]; other site
709991005166	metal binding site [ion binding]; metal-binding site
709991005167	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
709991005168	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
709991005169	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
709991005170	NifU-like domain; Region: NifU; cl00484
709991005171	Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368
709991005172	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
709991005173	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
709991005174	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
709991005175	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
709991005176	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
709991005177	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
709991005178	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
709991005179	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
709991005180	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
709991005181	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
709991005182	carboxyltransferase (CT) interaction site; other site
709991005183	biotinylation site [posttranslational modification]; other site
709991005184	Uncharacterized conserved protein [Function unknown]; Region: COG2966
709991005185	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
709991005186	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
709991005187	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
709991005188	metal binding site 2 [ion binding]; metal-binding site
709991005189	putative DNA binding helix; other site
709991005190	metal binding site 1 [ion binding]; metal-binding site
709991005191	dimer interface [polypeptide binding]; other site
709991005192	structural Zn2+ binding site [ion binding]; other site
709991005193	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
709991005194	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
709991005195	Soluble P-type ATPase [General function prediction only]; Region: COG4087
709991005196	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
709991005197	E-class dimer interface [polypeptide binding]; other site
709991005198	P-class dimer interface [polypeptide binding]; other site
709991005199	active site
709991005200	Cu2+ binding site [ion binding]; other site
709991005201	Zn2+ binding site [ion binding]; other site
709991005202	Clp protease; Region: CLP_protease; pfam00574
709991005203	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
709991005204	oligomer interface [polypeptide binding]; other site
709991005205	active site residues [active]
709991005206	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
709991005207	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
709991005208	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991005209	Walker A motif; other site
709991005210	ATP binding site [chemical binding]; other site
709991005211	Walker B motif; other site
709991005212	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
709991005213	Transposase domain (DUF772); Region: DUF772; pfam05598
709991005214	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991005215	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
709991005216	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
709991005217	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
709991005218	active site
709991005219	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
709991005220	active site
709991005221	Ap6A binding site [chemical binding]; other site
709991005222	nudix motif; other site
709991005223	metal binding site [ion binding]; metal-binding site
709991005224	Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]; Region: COG3178
709991005225	Phosphotransferase enzyme family; Region: APH; pfam01636
709991005226	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
709991005227	peptide chain release factor 2; Validated; Region: prfB; PRK00578
709991005228	This domain is found in peptide chain release factors; Region: PCRF; smart00937
709991005229	RF-1 domain; Region: RF-1; pfam00472
709991005230	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
709991005231	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
709991005232	putative ribose interaction site [chemical binding]; other site
709991005233	putative ADP binding site [chemical binding]; other site
709991005234	imidazole glycerol phosphate synthase subunit hisH; Provisional; Region: hisH; CHL00188
709991005235	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
709991005236	predicted active site [active]
709991005237	catalytic triad [active]
709991005238	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
709991005239	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
709991005240	active site
709991005241	multimer interface [polypeptide binding]; other site
709991005242	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
709991005243	active site
709991005244	catalytic residues [active]
709991005245	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
709991005246	Helix-turn-helix domain; Region: HTH_38; pfam13936
709991005247	Integrase core domain; Region: rve; pfam00665
709991005248	galactokinase; Provisional; Region: PRK05322
709991005249	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
709991005250	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
709991005251	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
709991005252	putative transporter; Provisional; Region: PRK10484
709991005253	Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) and related proteins; solute binding domain; Region: SLC5sbd_vSGLT; cd10325
709991005254	Na binding site [ion binding]; other site
709991005255	substrate binding site [chemical binding]; other site
709991005256	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
709991005257	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
709991005258	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991005259	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
709991005260	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991005261	DNA binding residues [nucleotide binding]
709991005262	Ribosomal protein L34; Region: Ribosomal_L34; cl00370
709991005263	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
709991005264	AIR carboxylase; Region: AIRC; pfam00731
709991005265	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
709991005266	active site
709991005267	GTPase CgtA; Reviewed; Region: obgE; PRK12299
709991005268	GTP1/OBG; Region: GTP1_OBG; pfam01018
709991005269	Obg GTPase; Region: Obg; cd01898
709991005270	G1 box; other site
709991005271	GTP/Mg2+ binding site [chemical binding]; other site
709991005272	Switch I region; other site
709991005273	G2 box; other site
709991005274	G3 box; other site
709991005275	Switch II region; other site
709991005276	G4 box; other site
709991005277	G5 box; other site
709991005278	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
709991005279	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
709991005280	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
709991005281	metal binding site [ion binding]; metal-binding site
709991005282	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
709991005283	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
709991005284	substrate binding site [chemical binding]; other site
709991005285	glutamase interaction surface [polypeptide binding]; other site
709991005286	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
709991005287	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
709991005288	catalytic residues [active]
709991005289	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
709991005290	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
709991005291	putative active site [active]
709991005292	oxyanion strand; other site
709991005293	catalytic triad [active]
709991005294	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
709991005295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991005296	active site
709991005297	motif I; other site
709991005298	motif II; other site
709991005299	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
709991005300	putative active site pocket [active]
709991005301	4-fold oligomerization interface [polypeptide binding]; other site
709991005302	metal binding residues [ion binding]; metal-binding site
709991005303	3-fold/trimer interface [polypeptide binding]; other site
709991005304	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
709991005305	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991005306	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991005307	homodimer interface [polypeptide binding]; other site
709991005308	catalytic residue [active]
709991005309	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
709991005310	histidinol dehydrogenase; Region: hisD; TIGR00069
709991005311	NAD binding site [chemical binding]; other site
709991005312	dimerization interface [polypeptide binding]; other site
709991005313	product binding site; other site
709991005314	substrate binding site [chemical binding]; other site
709991005315	zinc binding site [ion binding]; other site
709991005316	catalytic residues [active]
709991005317	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
709991005318	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
709991005319	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
709991005320	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3296
709991005321	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
709991005322	O-Antigen ligase; Region: Wzy_C; pfam04932
709991005323	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
709991005324	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991005325	binding surface
709991005326	TPR motif; other site
709991005327	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
709991005328	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
709991005329	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
709991005330	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991005331	ATP binding site [chemical binding]; other site
709991005332	Mg2+ binding site [ion binding]; other site
709991005333	G-X-G motif; other site
709991005334	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991005335	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991005336	active site
709991005337	phosphorylation site [posttranslational modification]
709991005338	intermolecular recognition site; other site
709991005339	dimerization interface [polypeptide binding]; other site
709991005340	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
709991005341	DNA binding site [nucleotide binding]
709991005342	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
709991005343	RNA binding surface [nucleotide binding]; other site
709991005344	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
709991005345	putative active site [active]
709991005346	catalytic residue [active]
709991005347	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
709991005348	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
709991005349	5S rRNA interface [nucleotide binding]; other site
709991005350	CTC domain interface [polypeptide binding]; other site
709991005351	L16 interface [polypeptide binding]; other site
709991005352	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
709991005353	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
709991005354	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
709991005355	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
709991005356	NAD synthetase; Provisional; Region: PRK13981
709991005357	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
709991005358	multimer interface [polypeptide binding]; other site
709991005359	active site
709991005360	catalytic triad [active]
709991005361	protein interface 1 [polypeptide binding]; other site
709991005362	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
709991005363	homodimer interface [polypeptide binding]; other site
709991005364	NAD binding pocket [chemical binding]; other site
709991005365	ATP binding pocket [chemical binding]; other site
709991005366	Mg binding site [ion binding]; other site
709991005367	active-site loop [active]
709991005368	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
709991005369	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
709991005370	ligand binding site [chemical binding]; other site
709991005371	flexible hinge region; other site
709991005372	Uncharacterized conserved protein [Function unknown]; Region: COG1284
709991005373	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
709991005374	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
709991005375	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
709991005376	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991005377	active site
709991005378	HIGH motif; other site
709991005379	nucleotide binding site [chemical binding]; other site
709991005380	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
709991005381	KMSKS motif; other site
709991005382	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
709991005383	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
709991005384	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
709991005385	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
709991005386	substrate binding pocket [chemical binding]; other site
709991005387	membrane-bound complex binding site; other site
709991005388	hinge residues; other site
709991005389	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
709991005390	N-acetyl-D-glucosamine binding site [chemical binding]; other site
709991005391	catalytic residue [active]
709991005392	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
709991005393	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
709991005394	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
709991005395	G1 box; other site
709991005396	GTP/Mg2+ binding site [chemical binding]; other site
709991005397	Switch I region; other site
709991005398	G2 box; other site
709991005399	G3 box; other site
709991005400	Switch II region; other site
709991005401	G4 box; other site
709991005402	G5 box; other site
709991005403	Nucleoside recognition; Region: Gate; pfam07670
709991005404	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
709991005405	Nucleoside recognition; Region: Gate; pfam07670
709991005406	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
709991005407	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
709991005408	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
709991005409	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
709991005410	Ligand Binding Site [chemical binding]; other site
709991005411	Predicted membrane protein [Function unknown]; Region: COG1470
709991005412	NPCBM-associated, NEW3 domain of alpha-galactosidase; Region: NPCBM_assoc; pfam10633
709991005413	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
709991005414	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
709991005415	Walker A/P-loop; other site
709991005416	ATP binding site [chemical binding]; other site
709991005417	Q-loop/lid; other site
709991005418	ABC transporter signature motif; other site
709991005419	Walker B; other site
709991005420	D-loop; other site
709991005421	H-loop/switch region; other site
709991005422	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
709991005423	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
709991005424	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
709991005425	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
709991005426	GDP-binding site [chemical binding]; other site
709991005427	ACT binding site; other site
709991005428	IMP binding site; other site
709991005429	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
709991005430	metal binding site 2 [ion binding]; metal-binding site
709991005431	putative DNA binding helix; other site
709991005432	metal binding site 1 [ion binding]; metal-binding site
709991005433	dimer interface [polypeptide binding]; other site
709991005434	structural Zn2+ binding site [ion binding]; other site
709991005435	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
709991005436	HD domain; Region: HD_4; pfam13328
709991005437	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
709991005438	synthetase active site [active]
709991005439	NTP binding site [chemical binding]; other site
709991005440	metal binding site [ion binding]; metal-binding site
709991005441	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
709991005442	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
709991005443	glutamate racemase; Provisional; Region: PRK00865
709991005444	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
709991005445	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
709991005446	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
709991005447	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
709991005448	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
709991005449	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
709991005450	Surface antigen; Region: Bac_surface_Ag; pfam01103
709991005451	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
709991005452	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
709991005453	catalytic residue [active]
709991005454	putative FPP diphosphate  binding site; other site
709991005455	putative FPP binding hydrophobic cleft; other site
709991005456	dimer interface [polypeptide binding]; other site
709991005457	putative IPP diphosphate binding site; other site
709991005458	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
709991005459	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
709991005460	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
709991005461	FOG: CBS domain [General function prediction only]; Region: COG0517
709991005462	Domain of unknown function (DUF4301); Region: DUF4301; pfam14134
709991005463	Domain of unknown function (DUF368); Region: DUF368; pfam04018
709991005464	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
709991005465	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
709991005466	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
709991005467	shikimate binding site; other site
709991005468	NAD(P) binding site [chemical binding]; other site
709991005469	indolepyruvate ferredoxin oxidoreductase, alpha subunit; Region: IOR_alpha; TIGR03336
709991005470	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
709991005471	dimer interface [polypeptide binding]; other site
709991005472	PYR/PP interface [polypeptide binding]; other site
709991005473	TPP binding site [chemical binding]; other site
709991005474	substrate binding site [chemical binding]; other site
709991005475	Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008
709991005476	TPP-binding site; other site
709991005477	indolepyruvate oxidoreductase subunit beta; Reviewed; Region: PRK06853
709991005478	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
709991005479	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
709991005480	Ligand binding site [chemical binding]; other site
709991005481	Electron transfer flavoprotein domain; Region: ETF; pfam01012
709991005482	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
709991005483	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
709991005484	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
709991005485	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
709991005486	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
709991005487	active site
709991005488	Acyl-CoA dehydrogenase C terminal; Region: AcylCoA_dehyd_C; pfam12186
709991005489	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
709991005490	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
709991005491	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
709991005492	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
709991005493	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
709991005494	protein binding site [polypeptide binding]; other site
709991005495	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
709991005496	Domain interface; other site
709991005497	Peptide binding site; other site
709991005498	Active site tetrad [active]
709991005499	asparagine synthetase AsnA; Provisional; Region: PRK05425
709991005500	motif 1; other site
709991005501	dimer interface [polypeptide binding]; other site
709991005502	active site
709991005503	motif 2; other site
709991005504	motif 3; other site
709991005505	Metal binding protein ZntC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: ZntC; cd01018
709991005506	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
709991005507	putative metal binding residues [ion binding]; other site
709991005508	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
709991005509	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
709991005510	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
709991005511	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
709991005512	ABC-ATPase subunit  interface; other site
709991005513	dimer interface [polypeptide binding]; other site
709991005514	putative PBP binding regions; other site
709991005515	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
709991005516	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
709991005517	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
709991005518	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
709991005519	trimer interface [polypeptide binding]; other site
709991005520	active site
709991005521	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
709991005522	homotrimer interaction site [polypeptide binding]; other site
709991005523	zinc binding site [ion binding]; other site
709991005524	CDP-binding sites; other site
709991005525	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
709991005526	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
709991005527	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
709991005528	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
709991005529	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
709991005530	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
709991005531	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
709991005532	Ligand binding site; other site
709991005533	Putative Catalytic site; other site
709991005534	DXD motif; other site
709991005535	dihydroorotase; Reviewed; Region: PRK09236
709991005536	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
709991005537	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
709991005538	active site
709991005539	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
709991005540	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
709991005541	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
709991005542	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
709991005543	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
709991005544	PAS fold; Region: PAS_4; pfam08448
709991005545	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
709991005546	putative active site [active]
709991005547	heme pocket [chemical binding]; other site
709991005548	FOG: PKD repeat [General function prediction only]; Region: COG3291
709991005549	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
709991005550	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
709991005551	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
709991005552	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
709991005553	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
709991005554	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
709991005555	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
709991005556	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991005557	dimer interface [polypeptide binding]; other site
709991005558	phosphorylation site [posttranslational modification]
709991005559	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991005560	ATP binding site [chemical binding]; other site
709991005561	Mg2+ binding site [ion binding]; other site
709991005562	G-X-G motif; other site
709991005563	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
709991005564	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
709991005565	Protein of unknown function (DUF2721); Region: DUF2721; pfam11026
709991005566	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
709991005567	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
709991005568	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
709991005569	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
709991005570	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
709991005571	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
709991005572	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
709991005573	Clp amino terminal domain; Region: Clp_N; pfam02861
709991005574	Clp amino terminal domain; Region: Clp_N; pfam02861
709991005575	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991005576	Walker A motif; other site
709991005577	ATP binding site [chemical binding]; other site
709991005578	Walker B motif; other site
709991005579	arginine finger; other site
709991005580	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991005581	Walker A motif; other site
709991005582	ATP binding site [chemical binding]; other site
709991005583	Walker B motif; other site
709991005584	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
709991005585	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
709991005586	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
709991005587	RNA methyltransferase, RsmE family; Region: TIGR00046
709991005588	TIR domain; Region: TIR_2; pfam13676
709991005589	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
709991005590	elongation factor G; Reviewed; Region: PRK12740
709991005591	G1 box; other site
709991005592	putative GEF interaction site [polypeptide binding]; other site
709991005593	GTP/Mg2+ binding site [chemical binding]; other site
709991005594	Switch I region; other site
709991005595	G2 box; other site
709991005596	G3 box; other site
709991005597	Switch II region; other site
709991005598	G4 box; other site
709991005599	G5 box; other site
709991005600	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
709991005601	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
709991005602	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
709991005603	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
709991005604	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991005605	FecR protein; Region: FecR; pfam04773
709991005606	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991005607	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991005608	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005609	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991005610	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991005611	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991005612	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991005613	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
709991005614	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
709991005615	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
709991005616	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991005617	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991005618	catalytic residues [active]
709991005619	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991005620	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991005621	IgA Peptidase M64; Region: Peptidase_M64; pfam09471
709991005622	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991005623	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991005624	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991005625	DNA binding residues [nucleotide binding]
709991005626	S-adenosylmethionine synthetase; Validated; Region: PRK05250
709991005627	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
709991005628	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
709991005629	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
709991005630	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
709991005631	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
709991005632	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
709991005633	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
709991005634	PS-10 peptidase S37; Region: Peptidase_S37; pfam05576
709991005635	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991005636	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
709991005637	cation binding site [ion binding]; other site
709991005638	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
709991005639	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991005640	motif II; other site
709991005641	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005642	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991005643	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991005644	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
709991005645	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
709991005646	ligand binding site [chemical binding]; other site
709991005647	flexible hinge region; other site
709991005648	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
709991005649	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
709991005650	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
709991005651	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991005652	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991005653	catalytic residues [active]
709991005654	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991005655	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991005656	catalytic residues [active]
709991005657	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991005658	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991005659	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991005660	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991005661	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005662	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991005663	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991005664	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991005665	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991005666	FecR protein; Region: FecR; pfam04773
709991005667	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005668	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991005669	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991005670	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991005671	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991005672	DNA binding residues [nucleotide binding]
709991005673	TIR domain; Region: TIR_2; pfam13676
709991005674	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
709991005675	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases; Region: MORN; smart00698
709991005676	MORN repeat; Region: MORN; cl14787
709991005677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
709991005678	MORN repeat; Region: MORN; cl14787
709991005679	MORN repeat; Region: MORN; cl14787
709991005680	MORN repeat; Region: MORN; cl14787
709991005681	MORN repeat; Region: MORN; pfam02493
709991005682	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
709991005683	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991005684	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991005685	ABC transporter; Region: ABC_tran_2; pfam12848
709991005686	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
709991005687	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
709991005688	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
709991005689	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991005690	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991005691	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991005692	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
709991005693	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991005694	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991005695	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991005696	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
709991005697	Transposase domain (DUF772); Region: DUF772; pfam05598
709991005698	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991005699	AAA domain; Region: AAA_14; pfam13173
709991005700	AAA domain; Region: AAA_22; pfam13401
709991005701	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
709991005702	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991005703	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991005704	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
709991005705	DNA binding residues [nucleotide binding]
709991005706	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
709991005707	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
709991005708	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005709	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
709991005710	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
709991005711	Penicillinase repressor; Region: Pencillinase_R; pfam03965
709991005712	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
709991005713	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
709991005714	homodimer interface [polypeptide binding]; other site
709991005715	substrate-cofactor binding pocket; other site
709991005716	catalytic residue [active]
709991005717	Peptidase S46; Region: Peptidase_S46; pfam10459
709991005718	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
709991005719	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
709991005720	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
709991005721	FeS/SAM binding site; other site
709991005722	glutamate dehydrogenase; Provisional; Region: PRK09414
709991005723	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
709991005724	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
709991005725	NAD(P) binding site [chemical binding]; other site
709991005726	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
709991005727	Transposase [DNA replication, recombination, and repair]; Region: COG5433
709991005728	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
709991005729	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
709991005730	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
709991005731	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
709991005732	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991005733	Uncharacterized conserved protein [Function unknown]; Region: COG5361
709991005734	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
709991005735	Protein of unknown function (DUF1214); Region: DUF1214; cl08447
709991005736	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
709991005737	Transposase [DNA replication, recombination, and repair]; Region: COG5433
709991005738	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
709991005739	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
709991005740	glucosamine-6-phosphate deaminase-like protein; Validated; Region: PRK02122
709991005741	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
709991005742	active site
709991005743	trimer interface [polypeptide binding]; other site
709991005744	allosteric site; other site
709991005745	active site lid [active]
709991005746	hexamer (dimer of trimers) interface [polypeptide binding]; other site
709991005747	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
709991005748	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991005749	active site
709991005750	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
709991005751	metal-binding site [ion binding]
709991005752	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005753	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991005754	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991005755	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991005756	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991005757	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991005758	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
709991005759	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
709991005760	putative active site [active]
709991005761	putative metal binding site [ion binding]; other site
709991005762	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
709991005763	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
709991005764	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991005765	Walker A motif; other site
709991005766	ATP binding site [chemical binding]; other site
709991005767	Walker B motif; other site
709991005768	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
709991005769	inorganic pyrophosphatase; Provisional; Region: PRK00642
709991005770	dimer interface [polypeptide binding]; other site
709991005771	substrate binding site [chemical binding]; other site
709991005772	metal binding sites [ion binding]; metal-binding site
709991005773	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
709991005774	dimer interface [polypeptide binding]; other site
709991005775	active site
709991005776	Transcriptional regulator [Transcription]; Region: LysR; COG0583
709991005777	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
709991005778	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
709991005779	dimerization interface [polypeptide binding]; other site
709991005780	chaperone protein DnaJ; Provisional; Region: PRK14289
709991005781	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
709991005782	HSP70 interaction site [polypeptide binding]; other site
709991005783	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
709991005784	substrate binding site [polypeptide binding]; other site
709991005785	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
709991005786	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
709991005787	dimer interface [polypeptide binding]; other site
709991005788	GrpE; Region: GrpE; pfam01025
709991005789	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
709991005790	dimer interface [polypeptide binding]; other site
709991005791	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
709991005792	hypothetical protein; Reviewed; Region: PRK00024
709991005793	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
709991005794	MPN+ (JAMM) motif; other site
709991005795	Zinc-binding site [ion binding]; other site
709991005796	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
709991005797	Predicted methyltransferases [General function prediction only]; Region: COG0313
709991005798	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
709991005799	putative SAM binding site [chemical binding]; other site
709991005800	putative homodimer interface [polypeptide binding]; other site
709991005801	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
709991005802	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991005803	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991005804	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991005805	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991005806	catalytic residues [active]
709991005807	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991005808	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991005809	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991005810	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991005811	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005812	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991005813	FecR protein; Region: FecR; pfam04773
709991005814	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991005815	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991005816	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991005817	biotin synthase; Provisional; Region: PRK07094
709991005818	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991005819	FeS/SAM binding site; other site
709991005820	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
709991005821	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
709991005822	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
709991005823	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
709991005824	putative acyl-acceptor binding pocket; other site
709991005825	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
709991005826	Protein of unknown function (DUF721); Region: DUF721; pfam05258
709991005827	recombination protein F; Reviewed; Region: recF; PRK00064
709991005828	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991005829	Walker A/P-loop; other site
709991005830	ATP binding site [chemical binding]; other site
709991005831	Q-loop/lid; other site
709991005832	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991005833	ABC transporter signature motif; other site
709991005834	Walker B; other site
709991005835	D-loop; other site
709991005836	H-loop/switch region; other site
709991005837	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
709991005838	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
709991005839	binding surface
709991005840	TPR motif; other site
709991005841	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
709991005842	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991005843	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991005844	catalytic residues [active]
709991005845	Transposase [DNA replication, recombination, and repair]; Region: COG5421
709991005846	2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed; Region: PRK11867
709991005847	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
709991005848	TPP-binding site [chemical binding]; other site
709991005849	2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710
709991005850	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
709991005851	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
709991005852	dimer interface [polypeptide binding]; other site
709991005853	PYR/PP interface [polypeptide binding]; other site
709991005854	TPP binding site [chemical binding]; other site
709991005855	substrate binding site [chemical binding]; other site
709991005856	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
709991005857	Mechanosensitive ion channel; Region: MS_channel; pfam00924
709991005858	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
709991005859	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
709991005860	oligomer interface [polypeptide binding]; other site
709991005861	metal binding site [ion binding]; metal-binding site
709991005862	metal binding site [ion binding]; metal-binding site
709991005863	Cl binding site [ion binding]; other site
709991005864	aspartate ring; other site
709991005865	basic sphincter; other site
709991005866	putative hydrophobic gate; other site
709991005867	periplasmic entrance; other site
709991005868	enolase; Provisional; Region: eno; PRK00077
709991005869	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
709991005870	dimer interface [polypeptide binding]; other site
709991005871	metal binding site [ion binding]; metal-binding site
709991005872	substrate binding pocket [chemical binding]; other site
709991005873	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
709991005874	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
709991005875	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
709991005876	alphaNTD - beta interaction site [polypeptide binding]; other site
709991005877	alphaNTD homodimer interface [polypeptide binding]; other site
709991005878	alphaNTD - beta' interaction site [polypeptide binding]; other site
709991005879	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
709991005880	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
709991005881	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
709991005882	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
709991005883	RNA binding surface [nucleotide binding]; other site
709991005884	30S ribosomal protein S11; Validated; Region: PRK05309
709991005885	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
709991005886	30S ribosomal protein S13; Region: bact_S13; TIGR03631
709991005887	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
709991005888	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
709991005889	rRNA binding site [nucleotide binding]; other site
709991005890	predicted 30S ribosome binding site; other site
709991005891	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
709991005892	active site
709991005893	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
709991005894	SecY translocase; Region: SecY; pfam00344
709991005895	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
709991005896	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
709991005897	23S rRNA binding site [nucleotide binding]; other site
709991005898	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
709991005899	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
709991005900	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
709991005901	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
709991005902	23S rRNA interface [nucleotide binding]; other site
709991005903	5S rRNA interface [nucleotide binding]; other site
709991005904	L27 interface [polypeptide binding]; other site
709991005905	L5 interface [polypeptide binding]; other site
709991005906	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
709991005907	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
709991005908	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
709991005909	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
709991005910	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
709991005911	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
709991005912	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
709991005913	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
709991005914	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
709991005915	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
709991005916	RNA binding site [nucleotide binding]; other site
709991005917	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
709991005918	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
709991005919	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
709991005920	23S rRNA interface [nucleotide binding]; other site
709991005921	putative translocon interaction site; other site
709991005922	signal recognition particle (SRP54) interaction site; other site
709991005923	L23 interface [polypeptide binding]; other site
709991005924	trigger factor interaction site; other site
709991005925	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
709991005926	23S rRNA interface [nucleotide binding]; other site
709991005927	5S rRNA interface [nucleotide binding]; other site
709991005928	putative antibiotic binding site [chemical binding]; other site
709991005929	L25 interface [polypeptide binding]; other site
709991005930	L27 interface [polypeptide binding]; other site
709991005931	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
709991005932	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
709991005933	G-X-X-G motif; other site
709991005934	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
709991005935	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
709991005936	putative translocon binding site; other site
709991005937	protein-rRNA interface [nucleotide binding]; other site
709991005938	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
709991005939	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
709991005940	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
709991005941	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
709991005942	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
709991005943	Ribosomal protein L4/L1 family; Region: Ribosomal_L4; cl00325
709991005944	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
709991005945	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
709991005946	elongation factor G; Reviewed; Region: PRK12739
709991005947	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
709991005948	G1 box; other site
709991005949	putative GEF interaction site [polypeptide binding]; other site
709991005950	GTP/Mg2+ binding site [chemical binding]; other site
709991005951	Switch I region; other site
709991005952	G2 box; other site
709991005953	G3 box; other site
709991005954	Switch II region; other site
709991005955	G4 box; other site
709991005956	G5 box; other site
709991005957	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
709991005958	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
709991005959	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
709991005960	30S ribosomal protein S7; Validated; Region: PRK05302
709991005961	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
709991005962	S17 interaction site [polypeptide binding]; other site
709991005963	S8 interaction site; other site
709991005964	16S rRNA interaction site [nucleotide binding]; other site
709991005965	streptomycin interaction site [chemical binding]; other site
709991005966	23S rRNA interaction site [nucleotide binding]; other site
709991005967	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
709991005968	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991005969	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991005970	potential frameshift: common BLAST hit: gi|150006492|ref|YP_001301236.1|  transposase
709991005971	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991005972	Transposase domain (DUF772); Region: DUF772; pfam05598
709991005973	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991005974	FecR protein; Region: FecR; pfam04773
709991005975	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991005976	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991005977	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991005978	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991005979	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991005980	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991005981	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991005982	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991005983	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991005984	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005985	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991005986	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991005987	FecR protein; Region: FecR; pfam04773
709991005988	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991005989	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991005990	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991005991	DNA binding residues [nucleotide binding]
709991005992	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991005993	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991005994	DNA binding residues [nucleotide binding]
709991005995	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991005996	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991005997	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991005998	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991005999	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991006000	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991006001	FecR protein; Region: FecR; pfam04773
709991006002	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991006003	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991006004	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006005	catalytic residues [active]
709991006006	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991006007	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006008	catalytic residues [active]
709991006009	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
709991006010	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991006011	Walker A motif; other site
709991006012	ATP binding site [chemical binding]; other site
709991006013	Walker B motif; other site
709991006014	arginine finger; other site
709991006015	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
709991006016	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991006017	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991006018	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991006019	DNA binding residues [nucleotide binding]
709991006020	FecR protein; Region: FecR; pfam04773
709991006021	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991006022	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991006023	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006024	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991006025	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991006026	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991006027	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991006028	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991006029	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006030	catalytic residues [active]
709991006031	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991006032	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991006033	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006034	catalytic residues [active]
709991006035	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991006036	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991006037	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006038	catalytic residues [active]
709991006039	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
709991006040	Lipopolysaccharide-assembly; Region: LptE; pfam04390
709991006041	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
709991006042	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
709991006043	oligomerisation interface [polypeptide binding]; other site
709991006044	mobile loop; other site
709991006045	roof hairpin; other site
709991006046	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
709991006047	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
709991006048	ring oligomerisation interface [polypeptide binding]; other site
709991006049	ATP/Mg binding site [chemical binding]; other site
709991006050	stacking interactions; other site
709991006051	hinge regions; other site
709991006052	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
709991006053	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
709991006054	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
709991006055	PhoU domain; Region: PhoU; pfam01895
709991006056	glycyl-tRNA synthetase; Provisional; Region: PRK04173
709991006057	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
709991006058	motif 1; other site
709991006059	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
709991006060	active site
709991006061	motif 2; other site
709991006062	motif 3; other site
709991006063	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
709991006064	anticodon binding site; other site
709991006065	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991006066	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991006067	ATP binding site [chemical binding]; other site
709991006068	Mg2+ binding site [ion binding]; other site
709991006069	G-X-G motif; other site
709991006070	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
709991006071	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991006072	active site
709991006073	phosphorylation site [posttranslational modification]
709991006074	intermolecular recognition site; other site
709991006075	dimerization interface [polypeptide binding]; other site
709991006076	Porin subfamily; Region: Porin_2; pfam02530
709991006077	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
709991006078	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
709991006079	active site
709991006080	Riboflavin kinase; Region: Flavokinase; smart00904
709991006081	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
709991006082	ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Region: NrdJ_Z; TIGR02504
709991006083	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
709991006084	active site
709991006085	dimer interface [polypeptide binding]; other site
709991006086	effector binding site; other site
709991006087	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
709991006088	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
709991006089	RimM N-terminal domain; Region: RimM; pfam01782
709991006090	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
709991006091	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
709991006092	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
709991006093	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
709991006094	active site
709991006095	catalytic residues [active]
709991006096	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
709991006097	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006098	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991006099	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991006100	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
709991006101	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991006102	Walker A/P-loop; other site
709991006103	ATP binding site [chemical binding]; other site
709991006104	Q-loop/lid; other site
709991006105	ABC transporter signature motif; other site
709991006106	Walker B; other site
709991006107	D-loop; other site
709991006108	H-loop/switch region; other site
709991006109	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
709991006110	active site
709991006111	SAM binding site [chemical binding]; other site
709991006112	homodimer interface [polypeptide binding]; other site
709991006113	Calx-beta domain; Region: Calx-beta; cl02522
709991006114	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991006115	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991006116	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991006117	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991006118	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006119	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991006120	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991006121	FecR protein; Region: FecR; pfam04773
709991006122	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991006123	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991006124	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991006125	DNA binding residues [nucleotide binding]
709991006126	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
709991006127	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
709991006128	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991006129	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
709991006130	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
709991006131	putative ligand binding site [chemical binding]; other site
709991006132	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
709991006133	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
709991006134	ABC-ATPase subunit  interface; other site
709991006135	dimer interface [polypeptide binding]; other site
709991006136	putative PBP binding regions; other site
709991006137	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
709991006138	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
709991006139	Walker A/P-loop; other site
709991006140	ATP binding site [chemical binding]; other site
709991006141	Q-loop/lid; other site
709991006142	ABC transporter signature motif; other site
709991006143	Walker B; other site
709991006144	D-loop; other site
709991006145	H-loop/switch region; other site
709991006146	flavodoxin FldA; Validated; Region: PRK09267
709991006147	Protein of unknown function (DUF2023); Region: DUF2023; pfam09633
709991006148	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
709991006149	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
709991006150	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
709991006151	Transposase IS200 like; Region: Y1_Tnp; cl00848
709991006152	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
709991006153	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
709991006154	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
709991006155	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
709991006156	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
709991006157	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
709991006158	active site
709991006159	SAM binding site [chemical binding]; other site
709991006160	homodimer interface [polypeptide binding]; other site
709991006161	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
709991006162	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
709991006163	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
709991006164	active site
709991006165	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
709991006166	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
709991006167	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
709991006168	active site
709991006169	putative homodimer interface [polypeptide binding]; other site
709991006170	SAM binding site [chemical binding]; other site
709991006171	precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Region: CbiT; TIGR02469
709991006172	S-adenosylmethionine binding site [chemical binding]; other site
709991006173	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
709991006174	Chloramphenicol acetyltransferase; Region: CAT; cl02008
709991006175	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
709991006176	active site
709991006177	SAM binding site [chemical binding]; other site
709991006178	homodimer interface [polypeptide binding]; other site
709991006179	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
709991006180	Precorrin-8X methylmutase; Region: CbiC; pfam02570
709991006181	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
709991006182	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991006183	N-terminal plug; other site
709991006184	ligand-binding site [chemical binding]; other site
709991006185	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
709991006186	Cobalt chelatase (CbiK); Region: CbiK; pfam06180
709991006187	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
709991006188	active site
709991006189	C-terminal domain interface [polypeptide binding]; other site
709991006190	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
709991006191	active site
709991006192	N-terminal domain interface [polypeptide binding]; other site
709991006193	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
709991006194	HsdM N-terminal domain; Region: HsdM_N; pfam12161
709991006195	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991006196	S-adenosylmethionine binding site [chemical binding]; other site
709991006197	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
709991006198	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
709991006199	ORF6N domain; Region: ORF6N; pfam10543
709991006200	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
709991006201	AAA domain; Region: AAA_14; pfam13173
709991006202	Histidine kinase; Region: His_kinase; pfam06580
709991006203	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
709991006204	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991006205	active site
709991006206	phosphorylation site [posttranslational modification]
709991006207	intermolecular recognition site; other site
709991006208	dimerization interface [polypeptide binding]; other site
709991006209	LytTr DNA-binding domain; Region: LytTR; pfam04397
709991006210	Domain of unknown function (DUF4062); Region: DUF4062; pfam13271
709991006211	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
709991006212	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
709991006213	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
709991006214	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
709991006215	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
709991006216	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
709991006217	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
709991006218	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
709991006219	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006220	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
709991006221	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991006222	N-terminal plug; other site
709991006223	ligand-binding site [chemical binding]; other site
709991006224	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
709991006225	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
709991006226	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006227	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
709991006228	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991006229	N-terminal plug; other site
709991006230	ligand-binding site [chemical binding]; other site
709991006231	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
709991006232	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
709991006233	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
709991006234	active site
709991006235	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
709991006236	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
709991006237	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
709991006238	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
709991006239	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
709991006240	active site
709991006241	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
709991006242	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
709991006243	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
709991006244	catalytic triad [active]
709991006245	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
709991006246	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
709991006247	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991006248	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991006249	homodimer interface [polypeptide binding]; other site
709991006250	catalytic residue [active]
709991006251	cobyric acid synthase; Provisional; Region: PRK00784
709991006252	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
709991006253	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
709991006254	catalytic triad [active]
709991006255	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
709991006256	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
709991006257	catalytic core [active]
709991006258	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
709991006259	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
709991006260	Probable transposase; Region: OrfB_IS605; pfam01385
709991006261	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
709991006262	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991006263	non-specific DNA binding site [nucleotide binding]; other site
709991006264	salt bridge; other site
709991006265	sequence-specific DNA binding site [nucleotide binding]; other site
709991006266	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
709991006267	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
709991006268	ligand binding site [chemical binding]; other site
709991006269	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991006270	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991006271	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006272	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991006273	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991006274	FecR protein; Region: FecR; pfam04773
709991006275	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991006276	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991006277	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991006278	DNA binding residues [nucleotide binding]
709991006279	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
709991006280	homotrimer interface [polypeptide binding]; other site
709991006281	Walker A motif; other site
709991006282	GTP binding site [chemical binding]; other site
709991006283	Walker B motif; other site
709991006284	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
709991006285	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
709991006286	putative dimer interface [polypeptide binding]; other site
709991006287	active site pocket [active]
709991006288	putative cataytic base [active]
709991006289	cobalamin synthase; Reviewed; Region: cobS; PRK00235
709991006290	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
709991006291	catalytic core [active]
709991006292	Abi-like protein; Region: Abi_2; pfam07751
709991006293	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
709991006294	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
709991006295	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
709991006296	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
709991006297	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
709991006298	N-terminal plug; other site
709991006299	ligand-binding site [chemical binding]; other site
709991006300	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
709991006301	CoA binding domain; Region: CoA_binding_2; pfam13380
709991006302	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
709991006303	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
709991006304	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
709991006305	AMP binding site [chemical binding]; other site
709991006306	metal binding site [ion binding]; metal-binding site
709991006307	active site
709991006308	Pyrococcus aspartate kinase subunit, putative; Region: AspKin_pair; TIGR02078
709991006309	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
709991006310	nucleotide binding site [chemical binding]; other site
709991006311	substrate binding site [chemical binding]; other site
709991006312	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
709991006313	Ligand binding site; other site
709991006314	Putative Catalytic site; other site
709991006315	DXD motif; other site
709991006316	isoleucyl-tRNA synthetase; Region: ileS; TIGR00392
709991006317	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991006318	active site
709991006319	HIGH motif; other site
709991006320	nucleotide binding site [chemical binding]; other site
709991006321	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991006322	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991006323	active site
709991006324	KMSKS motif; other site
709991006325	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
709991006326	tRNA binding surface [nucleotide binding]; other site
709991006327	anticodon binding site; other site
709991006328	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
709991006329	lipoprotein signal peptidase; Provisional; Region: PRK14788
709991006330	DNA topoisomerase I; Validated; Region: PRK06599
709991006331	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
709991006332	active site
709991006333	interdomain interaction site; other site
709991006334	putative metal-binding site [ion binding]; other site
709991006335	nucleotide binding site [chemical binding]; other site
709991006336	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
709991006337	domain I; other site
709991006338	DNA binding groove [nucleotide binding]
709991006339	phosphate binding site [ion binding]; other site
709991006340	domain II; other site
709991006341	domain III; other site
709991006342	nucleotide binding site [chemical binding]; other site
709991006343	catalytic site [active]
709991006344	domain IV; other site
709991006345	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
709991006346	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
709991006347	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
709991006348	SurA N-terminal domain; Region: SurA_N_3; cl07813
709991006349	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
709991006350	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
709991006351	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991006352	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991006353	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991006354	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006355	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991006356	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991006357	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
709991006358	active site
709991006359	catalytic site [active]
709991006360	substrate binding site [chemical binding]; other site
709991006361	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
709991006362	Fic/DOC family; Region: Fic; pfam02661
709991006363	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
709991006364	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991006365	active site
709991006366	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
709991006367	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991006368	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
709991006369	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
709991006370	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
709991006371	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
709991006372	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
709991006373	active site
709991006374	homodimer interface [polypeptide binding]; other site
709991006375	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
709991006376	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991006377	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
709991006378	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
709991006379	active site
709991006380	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
709991006381	putative ADP-binding pocket [chemical binding]; other site
709991006382	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991006383	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
709991006384	active site
709991006385	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
709991006386	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
709991006387	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991006388	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991006389	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
709991006390	Peptidase family U32; Region: Peptidase_U32; pfam01136
709991006391	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
709991006392	Penicillinase repressor; Region: Pencillinase_R; pfam03965
709991006393	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
709991006394	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
709991006395	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
709991006396	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
709991006397	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
709991006398	ribosome recycling factor; Reviewed; Region: frr; PRK00083
709991006399	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
709991006400	hinge region; other site
709991006401	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
709991006402	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
709991006403	Ligand binding site; other site
709991006404	oligomer interface; other site
709991006405	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
709991006406	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
709991006407	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
709991006408	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
709991006409	dimer interface [polypeptide binding]; other site
709991006410	active site
709991006411	CoA binding pocket [chemical binding]; other site
709991006412	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
709991006413	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
709991006414	GTPase RsgA; Reviewed; Region: PRK00098
709991006415	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
709991006416	RNA binding site [nucleotide binding]; other site
709991006417	homodimer interface [polypeptide binding]; other site
709991006418	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
709991006419	GTPase/Zn-binding domain interface [polypeptide binding]; other site
709991006420	GTP/Mg2+ binding site [chemical binding]; other site
709991006421	G4 box; other site
709991006422	G5 box; other site
709991006423	G1 box; other site
709991006424	Switch I region; other site
709991006425	G2 box; other site
709991006426	G3 box; other site
709991006427	Switch II region; other site
709991006428	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
709991006429	active site
709991006430	dimerization interface [polypeptide binding]; other site
709991006431	Recombination protein O N terminal; Region: RecO_N; pfam11967
709991006432	Recombination protein O C terminal; Region: RecO_C; pfam02565
709991006433	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
709991006434	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
709991006435	Walker A/P-loop; other site
709991006436	ATP binding site [chemical binding]; other site
709991006437	Q-loop/lid; other site
709991006438	ABC transporter signature motif; other site
709991006439	Walker B; other site
709991006440	D-loop; other site
709991006441	H-loop/switch region; other site
709991006442	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
709991006443	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
709991006444	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
709991006445	Outer membrane efflux protein; Region: OEP; pfam02321
709991006446	Outer membrane efflux protein; Region: OEP; pfam02321
709991006447	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
709991006448	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991006449	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991006450	Protein export membrane protein; Region: SecD_SecF; cl14618
709991006451	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991006452	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
709991006453	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
709991006454	Walker A/P-loop; other site
709991006455	ATP binding site [chemical binding]; other site
709991006456	Q-loop/lid; other site
709991006457	ABC transporter signature motif; other site
709991006458	Walker B; other site
709991006459	D-loop; other site
709991006460	H-loop/switch region; other site
709991006461	DNA primase, catalytic core; Region: dnaG; TIGR01391
709991006462	CHC2 zinc finger; Region: zf-CHC2; pfam01807
709991006463	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
709991006464	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
709991006465	active site
709991006466	metal binding site [ion binding]; metal-binding site
709991006467	interdomain interaction site; other site
709991006468	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991006469	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991006470	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
709991006471	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991006472	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991006473	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991006474	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991006475	Uncharacterized conserved protein [Function unknown]; Region: COG1284
709991006476	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
709991006477	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
709991006478	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
709991006479	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
709991006480	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991006481	FeS/SAM binding site; other site
709991006482	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; cl01319
709991006483	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
709991006484	ATP cone domain; Region: ATP-cone; pfam03477
709991006485	Class III ribonucleotide reductase; Region: RNR_III; cd01675
709991006486	effector binding site; other site
709991006487	active site
709991006488	Zn binding site [ion binding]; other site
709991006489	glycine loop; other site
709991006490	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
709991006491	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991006492	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
709991006493	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991006494	binding surface
709991006495	TPR motif; other site
709991006496	TPR repeat; Region: TPR_11; pfam13414
709991006497	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991006498	TPR motif; other site
709991006499	binding surface
709991006500	TPR repeat; Region: TPR_11; pfam13414
709991006501	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991006502	binding surface
709991006503	TPR motif; other site
709991006504	TPR repeat; Region: TPR_11; pfam13414
709991006505	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
709991006506	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
709991006507	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
709991006508	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
709991006509	Uncharacterized BCR, COG1636; Region: DUF208; pfam02677
709991006510	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
709991006511	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
709991006512	active site
709991006513	(T/H)XGH motif; other site
709991006514	GTP-binding protein LepA; Provisional; Region: PRK05433
709991006515	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
709991006516	G1 box; other site
709991006517	putative GEF interaction site [polypeptide binding]; other site
709991006518	GTP/Mg2+ binding site [chemical binding]; other site
709991006519	Switch I region; other site
709991006520	G2 box; other site
709991006521	G3 box; other site
709991006522	Switch II region; other site
709991006523	G4 box; other site
709991006524	G5 box; other site
709991006525	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
709991006526	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
709991006527	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
709991006528	hypothetical protein; Provisional; Region: PRK11820
709991006529	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
709991006530	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
709991006531	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
709991006532	four helix bundle protein; Region: TIGR02436
709991006533	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
709991006534	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
709991006535	catalytic site [active]
709991006536	G-X2-G-X-G-K; other site
709991006537	Uncharacterized conserved protein [Function unknown]; Region: COG1359
709991006538	Uncharacterized conserved protein [Function unknown]; Region: COG1359
709991006539	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
709991006540	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
709991006541	catalytic triad [active]
709991006542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991006543	Major Facilitator Superfamily; Region: MFS_1; pfam07690
709991006544	putative substrate translocation pore; other site
709991006545	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
709991006546	OmpA family; Region: OmpA; pfam00691
709991006547	ligand binding site [chemical binding]; other site
709991006548	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
709991006549	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
709991006550	N-ethylammeline chlorohydrolase; Provisional; Region: PRK09045
709991006551	active site
709991006552	putative substrate binding pocket [chemical binding]; other site
709991006553	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
709991006554	agmatinase; Region: agmatinase; TIGR01230
709991006555	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
709991006556	putative active site [active]
709991006557	Mn binding site [ion binding]; other site
709991006558	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
709991006559	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991006560	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991006561	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991006562	DNA binding residues [nucleotide binding]
709991006563	FecR protein; Region: FecR; pfam04773
709991006564	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991006565	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991006566	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991006567	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006568	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991006569	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
709991006570	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991006571	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991006572	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991006573	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991006574	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
709991006575	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991006576	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991006577	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006578	catalytic residues [active]
709991006579	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991006580	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991006581	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006582	catalytic residues [active]
709991006583	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
709991006584	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991006585	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006586	catalytic residues [active]
709991006587	maltose O-acetyltransferase; Provisional; Region: PRK10092
709991006588	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
709991006589	active site
709991006590	substrate binding site [chemical binding]; other site
709991006591	trimer interface [polypeptide binding]; other site
709991006592	CoA binding site [chemical binding]; other site
709991006593	arginine decarboxylase; Provisional; Region: PRK05354
709991006594	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
709991006595	dimer interface [polypeptide binding]; other site
709991006596	active site
709991006597	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
709991006598	catalytic residues [active]
709991006599	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
709991006600	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
709991006601	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
709991006602	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
709991006603	Uncharacterized conserved protein [Function unknown]; Region: COG4127
709991006604	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
709991006605	non-specific DNA binding site [nucleotide binding]; other site
709991006606	salt bridge; other site
709991006607	sequence-specific DNA binding site [nucleotide binding]; other site
709991006608	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
709991006609	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991006610	dimerization interface [polypeptide binding]; other site
709991006611	DNA binding residues [nucleotide binding]
709991006612	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
709991006613	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
709991006614	DNA primase, catalytic core; Region: dnaG; TIGR01391
709991006615	CHC2 zinc finger; Region: zf-CHC2; pfam01807
709991006616	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
709991006617	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
709991006618	active site
709991006619	metal binding site [ion binding]; metal-binding site
709991006620	interdomain interaction site; other site
709991006621	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
709991006622	oligomer interface [polypeptide binding]; other site
709991006623	active site residues [active]
709991006624	elongation factor P; Provisional; Region: PRK14578
709991006625	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
709991006626	amidase catalytic site [active]
709991006627	Zn binding residues [ion binding]; other site
709991006628	substrate binding site [chemical binding]; other site
709991006629	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
709991006630	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
709991006631	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
709991006632	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
709991006633	active site
709991006634	catalytic residues [active]
709991006635	DNA binding site [nucleotide binding]
709991006636	Int/Topo IB signature motif; other site
709991006637	Ribosome-binding factor A; Region: RBFA; pfam02033
709991006638	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
709991006639	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991006640	FtsX-like permease family; Region: FtsX; pfam02687
709991006641	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
709991006642	active site
709991006643	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
709991006644	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
709991006645	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
709991006646	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
709991006647	dimer interface [polypeptide binding]; other site
709991006648	motif 1; other site
709991006649	active site
709991006650	motif 2; other site
709991006651	motif 3; other site
709991006652	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
709991006653	ligand binding site [chemical binding]; other site
709991006654	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
709991006655	Protein of unknown function (DUF3897); Region: DUF3897; pfam13036
709991006656	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
709991006657	hypothetical protein; Provisional; Region: PRK08201
709991006658	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
709991006659	metal binding site [ion binding]; metal-binding site
709991006660	putative dimer interface [polypeptide binding]; other site
709991006661	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
709991006662	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
709991006663	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
709991006664	active site
709991006665	Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044
709991006666	diiron binding motif [ion binding]; other site
709991006667	CCC1-related domain of ferritin; Region: Ferritin_CCC1_C; cd02431
709991006668	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
709991006669	Na binding site [ion binding]; other site
709991006670	leucyl-tRNA synthetase, eubacterial and mitochondrial family; Region: leuS_bact; TIGR00396
709991006671	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
709991006672	HIGH motif; other site
709991006673	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991006674	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
709991006675	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991006676	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
709991006677	active site
709991006678	KMSKS motif; other site
709991006679	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
709991006680	tRNA binding surface [nucleotide binding]; other site
709991006681	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2832
709991006682	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
709991006683	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
709991006684	FMN binding site [chemical binding]; other site
709991006685	active site
709991006686	catalytic residues [active]
709991006687	substrate binding site [chemical binding]; other site
709991006688	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
709991006689	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
709991006690	putative Zn2+ binding site [ion binding]; other site
709991006691	putative DNA binding site [nucleotide binding]; other site
709991006692	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
709991006693	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
709991006694	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991006695	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006696	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991006697	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991006698	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991006699	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991006700	Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; Region: EGF_CA; cl09941
709991006701	Ca2+ binding site [ion binding]; other site
709991006702	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991006703	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006704	catalytic residues [active]
709991006705	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
709991006706	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
709991006707	active site
709991006708	substrate binding site [chemical binding]; other site
709991006709	Mg2+ binding site [ion binding]; other site
709991006710	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
709991006711	C-terminal peptidase (prc); Region: prc; TIGR00225
709991006712	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
709991006713	protein binding site [polypeptide binding]; other site
709991006714	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
709991006715	Catalytic dyad [active]
709991006716	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
709991006717	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
709991006718	substrate binding pocket [chemical binding]; other site
709991006719	chain length determination region; other site
709991006720	substrate-Mg2+ binding site; other site
709991006721	catalytic residues [active]
709991006722	aspartate-rich region 1; other site
709991006723	active site lid residues [active]
709991006724	aspartate-rich region 2; other site
709991006725	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
709991006726	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
709991006727	dimer interface [polypeptide binding]; other site
709991006728	active site
709991006729	metal binding site [ion binding]; metal-binding site
709991006730	Predicted acetyltransferase [General function prediction only]; Region: COG2388
709991006731	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
709991006732	putative active site [active]
709991006733	dimerization interface [polypeptide binding]; other site
709991006734	putative tRNAtyr binding site [nucleotide binding]; other site
709991006735	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
709991006736	homodimer interface [polypeptide binding]; other site
709991006737	metal binding site [ion binding]; metal-binding site
709991006738	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
709991006739	Protein export membrane protein; Region: SecD_SecF; cl14618
709991006740	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
709991006741	intersubunit interface [polypeptide binding]; other site
709991006742	active site
709991006743	catalytic residue [active]
709991006744	Protein of unknown function (DUF419); Region: DUF419; pfam04237
709991006745	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
709991006746	MutS domain I; Region: MutS_I; pfam01624
709991006747	MutS domain II; Region: MutS_II; pfam05188
709991006748	MutS domain III; Region: MutS_III; pfam05192
709991006749	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
709991006750	Walker A/P-loop; other site
709991006751	ATP binding site [chemical binding]; other site
709991006752	Q-loop/lid; other site
709991006753	ABC transporter signature motif; other site
709991006754	Walker B; other site
709991006755	D-loop; other site
709991006756	H-loop/switch region; other site
709991006757	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991006758	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991006759	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006760	catalytic residues [active]
709991006761	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991006762	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006763	catalytic residues [active]
709991006764	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991006765	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991006766	catalytic residues [active]
709991006767	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991006768	SusD family; Region: SusD; pfam07980
709991006769	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991006770	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991006771	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006772	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991006773	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991006774	FecR protein; Region: FecR; pfam04773
709991006775	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991006776	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991006777	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991006778	DNA binding residues [nucleotide binding]
709991006779	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
709991006780	active site
709991006781	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
709991006782	Sporulation related domain; Region: SPOR; pfam05036
709991006783	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
709991006784	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
709991006785	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
709991006786	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
709991006787	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
709991006788	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
709991006789	putative dimer interface [polypeptide binding]; other site
709991006790	putative anticodon binding site; other site
709991006791	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
709991006792	homodimer interface [polypeptide binding]; other site
709991006793	motif 1; other site
709991006794	motif 2; other site
709991006795	active site
709991006796	motif 3; other site
709991006797	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
709991006798	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991006799	FeS/SAM binding site; other site
709991006800	HemN C-terminal domain; Region: HemN_C; pfam06969
709991006801	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991006802	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991006803	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991006804	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
709991006805	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
709991006806	23S rRNA interface [nucleotide binding]; other site
709991006807	L3 interface [polypeptide binding]; other site
709991006808	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
709991006809	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
709991006810	rRNA interaction site [nucleotide binding]; other site
709991006811	S8 interaction site; other site
709991006812	putative laminin-1 binding site; other site
709991006813	elongation factor Ts; Provisional; Region: tsf; PRK09377
709991006814	Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153
709991006815	Elongation factor TS; Region: EF_TS; pfam00889
709991006816	Elongation factor TS; Region: EF_TS; pfam00889
709991006817	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
709991006818	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; cl01627
709991006819	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; cl01627
709991006820	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991006821	active site
709991006822	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
709991006823	Sulfatase; Region: Sulfatase; pfam00884
709991006824	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
709991006825	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
709991006826	Ligand binding site; other site
709991006827	Putative Catalytic site; other site
709991006828	DXD motif; other site
709991006829	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
709991006830	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
709991006831	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
709991006832	putative nucleotide binding site [chemical binding]; other site
709991006833	uridine monophosphate binding site [chemical binding]; other site
709991006834	homohexameric interface [polypeptide binding]; other site
709991006835	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
709991006836	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
709991006837	TPP-binding site; other site
709991006838	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
709991006839	PYR/PP interface [polypeptide binding]; other site
709991006840	dimer interface [polypeptide binding]; other site
709991006841	TPP binding site [chemical binding]; other site
709991006842	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
709991006843	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
709991006844	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
709991006845	ligand binding site [chemical binding]; other site
709991006846	flexible hinge region; other site
709991006847	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
709991006848	putative switch regulator; other site
709991006849	non-specific DNA interactions [nucleotide binding]; other site
709991006850	DNA binding site [nucleotide binding]
709991006851	sequence specific DNA binding site [nucleotide binding]; other site
709991006852	putative cAMP binding site [chemical binding]; other site
709991006853	aspartate aminotransferase; Provisional; Region: PRK07568
709991006854	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991006855	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991006856	homodimer interface [polypeptide binding]; other site
709991006857	catalytic residue [active]
709991006858	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
709991006859	putative acyl-acceptor binding pocket; other site
709991006860	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
709991006861	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
709991006862	active site
709991006863	HIGH motif; other site
709991006864	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
709991006865	active site
709991006866	KMSKS motif; other site
709991006867	Tic20-like protein; Region: Tic20; pfam09685
709991006868	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
709991006869	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
709991006870	FMN binding site [chemical binding]; other site
709991006871	active site
709991006872	catalytic residues [active]
709991006873	substrate binding site [chemical binding]; other site
709991006874	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
709991006875	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991006876	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991006877	DNA binding residues [nucleotide binding]
709991006878	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991006879	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
709991006880	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
709991006881	Chorismate mutase type II; Region: CM_2; smart00830
709991006882	prephenate dehydrogenase; Validated; Region: PRK08507
709991006883	Prephenate dehydrogenase; Region: PDH; pfam02153
709991006884	LL-diaminopimelate aminotransferase; Provisional; Region: PRK09276
709991006885	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991006886	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991006887	homodimer interface [polypeptide binding]; other site
709991006888	catalytic residue [active]
709991006889	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
709991006890	Prephenate dehydratase; Region: PDT; pfam00800
709991006891	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
709991006892	putative L-Phe binding site [chemical binding]; other site
709991006893	DNA polymerase I; Provisional; Region: PRK05755
709991006894	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
709991006895	active site
709991006896	metal binding site 1 [ion binding]; metal-binding site
709991006897	putative 5' ssDNA interaction site; other site
709991006898	metal binding site 3; metal-binding site
709991006899	metal binding site 2 [ion binding]; metal-binding site
709991006900	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
709991006901	putative DNA binding site [nucleotide binding]; other site
709991006902	putative metal binding site [ion binding]; other site
709991006903	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
709991006904	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
709991006905	active site
709991006906	DNA binding site [nucleotide binding]
709991006907	catalytic site [active]
709991006908	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
709991006909	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
709991006910	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
709991006911	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
709991006912	active site
709991006913	ribonuclease P; Reviewed; Region: rnpA; PRK01903
709991006914	Haemolytic domain; Region: Haemolytic; pfam01809
709991006915	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
709991006916	C-terminal peptidase (prc); Region: prc; TIGR00225
709991006917	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
709991006918	protein binding site [polypeptide binding]; other site
709991006919	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
709991006920	Catalytic dyad [active]
709991006921	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
709991006922	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
709991006923	GIY-YIG motif/motif A; other site
709991006924	active site
709991006925	catalytic site [active]
709991006926	putative DNA binding site [nucleotide binding]; other site
709991006927	metal binding site [ion binding]; metal-binding site
709991006928	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
709991006929	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
709991006930	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
709991006931	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
709991006932	active site
709991006933	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
709991006934	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
709991006935	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
709991006936	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
709991006937	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
709991006938	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
709991006939	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991006940	ATP binding site [chemical binding]; other site
709991006941	Mg2+ binding site [ion binding]; other site
709991006942	G-X-G motif; other site
709991006943	Domain of unknown function (DUF4175); Region: DUF4175; pfam13779
709991006944	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
709991006945	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
709991006946	Peptidase family M23; Region: Peptidase_M23; pfam01551
709991006947	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
709991006948	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991006949	TPR motif; other site
709991006950	binding surface
709991006951	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991006952	binding surface
709991006953	TPR motif; other site
709991006954	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991006955	binding surface
709991006956	TPR motif; other site
709991006957	TPR repeat; Region: TPR_11; pfam13414
709991006958	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991006959	binding surface
709991006960	TPR motif; other site
709991006961	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
709991006962	trimer interface [polypeptide binding]; other site
709991006963	active site
709991006964	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
709991006965	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
709991006966	active site
709991006967	nucleotide binding site [chemical binding]; other site
709991006968	HIGH motif; other site
709991006969	KMSKS motif; other site
709991006970	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
709991006971	tetramerization interface [polypeptide binding]; other site
709991006972	active site
709991006973	pantoate--beta-alanine ligase; Region: panC; TIGR00018
709991006974	Pantoate-beta-alanine ligase; Region: PanC; cd00560
709991006975	active site
709991006976	ATP-binding site [chemical binding]; other site
709991006977	pantoate-binding site; other site
709991006978	HXXH motif; other site
709991006979	Arginine repressor [Transcription]; Region: ArgR; COG1438
709991006980	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
709991006981	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
709991006982	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
709991006983	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
709991006984	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
709991006985	catalytic site [active]
709991006986	subunit interface [polypeptide binding]; other site
709991006987	carbamoyl-phosphate synthase, large subunit; Region: CPSaseII_lrg; TIGR01369
709991006988	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
709991006989	ATP-grasp domain; Region: ATP-grasp_4; cl17255
709991006990	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
709991006991	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
709991006992	ATP-grasp domain; Region: ATP-grasp_4; cl17255
709991006993	Methylglyoxal synthase-like domain found in pyr1 and URA1-like carbamoyl phosphate synthetases (CPS), including ammonia-dependent CPS Type I, and glutamine-dependent CPS Type III. These are multidomain proteins, in which MGS is the C-terminal domain; Region: MGS_CPS_I_III; cd01423
709991006994	probable substrate binding site [chemical binding]; other site
709991006995	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991006996	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991006997	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991006998	DNA binding residues [nucleotide binding]
709991006999	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991007000	FecR protein; Region: FecR; pfam04773
709991007001	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991007002	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991007003	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991007004	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991007005	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991007006	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991007007	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
709991007008	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
709991007009	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
709991007010	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
709991007011	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991007012	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991007013	AAA domain; Region: AAA_21; pfam13304
709991007014	Walker A/P-loop; other site
709991007015	ATP binding site [chemical binding]; other site
709991007016	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991007017	Q-loop/lid; other site
709991007018	ABC transporter signature motif; other site
709991007019	Walker B; other site
709991007020	D-loop; other site
709991007021	H-loop/switch region; other site
709991007022	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
709991007023	Transglycosylase; Region: Transgly; pfam00912
709991007024	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
709991007025	DNA repair protein RadA; Provisional; Region: PRK11823
709991007026	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
709991007027	Walker A motif/ATP binding site; other site
709991007028	ATP binding site [chemical binding]; other site
709991007029	Walker B motif; other site
709991007030	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
709991007031	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
709991007032	ligand binding site [chemical binding]; other site
709991007033	OmpA family; Region: OmpA; pfam00691
709991007034	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991007035	multiple promoter invertase; Provisional; Region: mpi; PRK13413
709991007036	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
709991007037	catalytic residues [active]
709991007038	catalytic nucleophile [active]
709991007039	Presynaptic Site I dimer interface [polypeptide binding]; other site
709991007040	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
709991007041	Synaptic Flat tetramer interface [polypeptide binding]; other site
709991007042	Synaptic Site I dimer interface [polypeptide binding]; other site
709991007043	DNA binding site [nucleotide binding]
709991007044	hypothetical protein; Provisional; Region: PRK12378
709991007045	Leucine rich repeat; Region: LRR_8; pfam13855
709991007046	Transcriptional regulators [Transcription]; Region: PurR; COG1609
709991007047	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
709991007048	DNA binding site [nucleotide binding]
709991007049	domain linker motif; other site
709991007050	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
709991007051	ligand binding site [chemical binding]; other site
709991007052	dimerization interface [polypeptide binding]; other site
709991007053	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
709991007054	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
709991007055	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
709991007056	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
709991007057	catalytic residue [active]
709991007058	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
709991007059	catalytic residues [active]
709991007060	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
709991007061	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
709991007062	peroxiredoxin; Region: AhpC; TIGR03137
709991007063	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
709991007064	dimer interface [polypeptide binding]; other site
709991007065	decamer (pentamer of dimers) interface [polypeptide binding]; other site
709991007066	catalytic triad [active]
709991007067	peroxidatic and resolving cysteines [active]
709991007068	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
709991007069	active site
709991007070	Uncharacterized Fe-S center protein [General function prediction only]; Region: COG2768
709991007071	4Fe-4S binding domain; Region: Fer4; pfam00037
709991007072	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
709991007073	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
709991007074	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
709991007075	putative active site [active]
709991007076	putative catalytic site [active]
709991007077	putative DNA binding site [nucleotide binding]; other site
709991007078	putative phosphate binding site [ion binding]; other site
709991007079	metal binding site A [ion binding]; metal-binding site
709991007080	putative AP binding site [nucleotide binding]; other site
709991007081	putative metal binding site B [ion binding]; other site
709991007082	M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658
709991007083	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
709991007084	active site
709991007085	metal binding site [ion binding]; metal-binding site
709991007086	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
709991007087	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
709991007088	dimerization interface [polypeptide binding]; other site
709991007089	DPS ferroxidase diiron center [ion binding]; other site
709991007090	ion pore; other site
709991007091	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
709991007092	EamA-like transporter family; Region: EamA; pfam00892
709991007093	EamA-like transporter family; Region: EamA; pfam00892
709991007094	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
709991007095	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991007096	Uncharacterized conserved protein [Function unknown]; Region: COG3391
709991007097	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
709991007098	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991007099	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
709991007100	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
709991007101	putative ligand binding site [chemical binding]; other site
709991007102	Peptidase C10 family; Region: Peptidase_C10; pfam01640
709991007103	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991007104	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
709991007105	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
709991007106	ABC-ATPase subunit  interface; other site
709991007107	dimer interface [polypeptide binding]; other site
709991007108	putative PBP binding regions; other site
709991007109	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
709991007110	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
709991007111	Walker A/P-loop; other site
709991007112	ATP binding site [chemical binding]; other site
709991007113	Q-loop/lid; other site
709991007114	ABC transporter signature motif; other site
709991007115	Walker B; other site
709991007116	D-loop; other site
709991007117	H-loop/switch region; other site
709991007118	Predicted metal-binding protein (DUF2284); Region: DUF2284; pfam10050
709991007119	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
709991007120	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
709991007121	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991007122	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991007123	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
709991007124	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
709991007125	Outer membrane efflux protein; Region: OEP; pfam02321
709991007126	Outer membrane efflux protein; Region: OEP; pfam02321
709991007127	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
709991007128	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991007129	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
709991007130	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
709991007131	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
709991007132	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
709991007133	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
709991007134	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
709991007135	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991007136	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991007137	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991007138	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991007139	Outer membrane efflux protein; Region: OEP; pfam02321
709991007140	Outer membrane efflux protein; Region: OEP; pfam02321
709991007141	multiple promoter invertase; Provisional; Region: mpi; PRK13413
709991007142	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
709991007143	catalytic residues [active]
709991007144	catalytic nucleophile [active]
709991007145	Presynaptic Site I dimer interface [polypeptide binding]; other site
709991007146	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
709991007147	Synaptic Flat tetramer interface [polypeptide binding]; other site
709991007148	Synaptic Site I dimer interface [polypeptide binding]; other site
709991007149	DNA binding site [nucleotide binding]
709991007150	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
709991007151	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
709991007152	HlyD family secretion protein; Region: HlyD_3; pfam13437
709991007153	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
709991007154	Outer membrane efflux protein; Region: OEP; pfam02321
709991007155	Outer membrane efflux protein; Region: OEP; pfam02321
709991007156	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
709991007157	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
709991007158	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
709991007159	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
709991007160	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
709991007161	protein binding site [polypeptide binding]; other site
709991007162	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
709991007163	Domain interface; other site
709991007164	Peptide binding site; other site
709991007165	Active site tetrad [active]
709991007166	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
709991007167	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
709991007168	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
709991007169	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
709991007170	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
709991007171	Coenzyme A binding pocket [chemical binding]; other site
709991007172	argininosuccinate synthase; Provisional; Region: PRK13820
709991007173	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
709991007174	Ligand Binding Site [chemical binding]; other site
709991007175	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
709991007176	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
709991007177	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
709991007178	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
709991007179	inhibitor-cofactor binding pocket; inhibition site
709991007180	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991007181	catalytic residue [active]
709991007182	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
709991007183	nucleotide binding site [chemical binding]; other site
709991007184	N-acetyl-L-glutamate binding site [chemical binding]; other site
709991007185	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
709991007186	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like5; cd05651
709991007187	metal binding site [ion binding]; metal-binding site
709991007188	dimer interface [polypeptide binding]; other site
709991007189	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
709991007190	active sites [active]
709991007191	Lyase; Region: Lyase_1; pfam00206
709991007192	tetramer interface [polypeptide binding]; other site
709991007193	Inner membrane protein CreD; Region: CreD; pfam06123
709991007194	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
709991007195	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
709991007196	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991007197	active site
709991007198	phosphorylation site [posttranslational modification]
709991007199	intermolecular recognition site; other site
709991007200	dimerization interface [polypeptide binding]; other site
709991007201	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991007202	Walker A motif; other site
709991007203	ATP binding site [chemical binding]; other site
709991007204	Walker B motif; other site
709991007205	arginine finger; other site
709991007206	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
709991007207	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
709991007208	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
709991007209	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
709991007210	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
709991007211	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
709991007212	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
709991007213	Coagulation factor 5/8 C-terminal domain, discoidin domain; Region: FA58C; smart00231
709991007214	sugar binding site [chemical binding]; other site
709991007215	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991007216	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991007217	dimer interface [polypeptide binding]; other site
709991007218	phosphorylation site [posttranslational modification]
709991007219	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991007220	ATP binding site [chemical binding]; other site
709991007221	Mg2+ binding site [ion binding]; other site
709991007222	G-X-G motif; other site
709991007223	Response regulator receiver domain; Region: Response_reg; pfam00072
709991007224	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991007225	active site
709991007226	phosphorylation site [posttranslational modification]
709991007227	intermolecular recognition site; other site
709991007228	dimerization interface [polypeptide binding]; other site
709991007229	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
709991007230	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
709991007231	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
709991007232	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
709991007233	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
709991007234	active site
709991007235	homodimer interface [polypeptide binding]; other site
709991007236	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
709991007237	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
709991007238	active site
709991007239	glutamate dehydrogenase; Provisional; Region: PRK09414
709991007240	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
709991007241	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
709991007242	NAD(P) binding site [chemical binding]; other site
709991007243	DNA protecting protein DprA; Region: dprA; TIGR00732
709991007244	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
709991007245	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
709991007246	active site
709991007247	dimer interface [polypeptide binding]; other site
709991007248	metal binding site [ion binding]; metal-binding site
709991007249	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
709991007250	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
709991007251	hinge; other site
709991007252	active site
709991007253	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
709991007254	nucleoside/Zn binding site; other site
709991007255	dimer interface [polypeptide binding]; other site
709991007256	catalytic motif [active]
709991007257	Phosphoglycerate kinase; Region: PGK; pfam00162
709991007258	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
709991007259	substrate binding site [chemical binding]; other site
709991007260	hinge regions; other site
709991007261	ADP binding site [chemical binding]; other site
709991007262	catalytic site [active]
709991007263	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
709991007264	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
709991007265	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
709991007266	catalytic residue [active]
709991007267	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
709991007268	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
709991007269	ligand binding site [chemical binding]; other site
709991007270	flexible hinge region; other site
709991007271	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
709991007272	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
709991007273	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
709991007274	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
709991007275	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
709991007276	putative Zn2+ binding site [ion binding]; other site
709991007277	putative DNA binding site [nucleotide binding]; other site
709991007278	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
709991007279	TrkA-N domain; Region: TrkA_N; pfam02254
709991007280	TrkA-C domain; Region: TrkA_C; pfam02080
709991007281	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
709991007282	Cation transport protein; Region: TrkH; cl17365
709991007283	Protein of unknown function, DUF486; Region: DUF486; cl01236
709991007284	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991007285	AAA domain; Region: AAA_21; pfam13304
709991007286	Walker A/P-loop; other site
709991007287	ATP binding site [chemical binding]; other site
709991007288	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
709991007289	ATP binding site [chemical binding]; other site
709991007290	Q-loop/lid; other site
709991007291	ABC transporter signature motif; other site
709991007292	Walker B; other site
709991007293	D-loop; other site
709991007294	H-loop/switch region; other site
709991007295	four helix bundle protein; Region: TIGR02436
709991007296	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
709991007297	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
709991007298	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991007299	Walker A motif; other site
709991007300	ATP binding site [chemical binding]; other site
709991007301	Walker B motif; other site
709991007302	arginine finger; other site
709991007303	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
709991007304	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991007305	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991007306	dimer interface [polypeptide binding]; other site
709991007307	phosphorylation site [posttranslational modification]
709991007308	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991007309	ATP binding site [chemical binding]; other site
709991007310	Mg2+ binding site [ion binding]; other site
709991007311	G-X-G motif; other site
709991007312	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991007313	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991007314	active site
709991007315	phosphorylation site [posttranslational modification]
709991007316	intermolecular recognition site; other site
709991007317	dimerization interface [polypeptide binding]; other site
709991007318	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
709991007319	DNA binding site [nucleotide binding]
709991007320	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
709991007321	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991007322	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991007323	catalytic residues [active]
709991007324	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
709991007325	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
709991007326	Walker A/P-loop; other site
709991007327	ATP binding site [chemical binding]; other site
709991007328	Q-loop/lid; other site
709991007329	ABC transporter signature motif; other site
709991007330	Walker B; other site
709991007331	D-loop; other site
709991007332	H-loop/switch region; other site
709991007333	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
709991007334	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991007335	ATP binding site [chemical binding]; other site
709991007336	Mg2+ binding site [ion binding]; other site
709991007337	G-X-G motif; other site
709991007338	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
709991007339	ATP binding site [chemical binding]; other site
709991007340	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
709991007341	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
709991007342	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
709991007343	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
709991007344	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
709991007345	Rhomboid family; Region: Rhomboid; cl11446
709991007346	Rhomboid family; Region: Rhomboid; pfam01694
709991007347	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
709991007348	PSP1 C-terminal conserved region; Region: PSP1; cl00770
709991007349	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
709991007350	DNA polymerase III subunit delta'; Validated; Region: PRK08485
709991007351	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
709991007352	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
709991007353	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
709991007354	dimer interface [polypeptide binding]; other site
709991007355	anticodon binding site; other site
709991007356	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
709991007357	homodimer interface [polypeptide binding]; other site
709991007358	motif 1; other site
709991007359	active site
709991007360	motif 2; other site
709991007361	GAD domain; Region: GAD; pfam02938
709991007362	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
709991007363	motif 3; other site
709991007364	Colicin V production protein; Region: Colicin_V; pfam02674
709991007365	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
709991007366	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
709991007367	active site
709991007368	HIGH motif; other site
709991007369	dimer interface [polypeptide binding]; other site
709991007370	KMSKS motif; other site
709991007371	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
709991007372	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
709991007373	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
709991007374	HflX GTPase family; Region: HflX; cd01878
709991007375	G1 box; other site
709991007376	GTP/Mg2+ binding site [chemical binding]; other site
709991007377	Switch I region; other site
709991007378	G2 box; other site
709991007379	G3 box; other site
709991007380	Switch II region; other site
709991007381	G4 box; other site
709991007382	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
709991007383	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
709991007384	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
709991007385	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
709991007386	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
709991007387	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
709991007388	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
709991007389	Sulfatase; Region: Sulfatase; pfam00884
709991007390	Surface antigen; Region: Bac_surface_Ag; pfam01103
709991007391	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; cl17398
709991007392	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991007393	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991007394	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991007395	DNA binding residues [nucleotide binding]
709991007396	FecR protein; Region: FecR; pfam04773
709991007397	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991007398	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991007399	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991007400	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991007401	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991007402	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991007403	Minimal MMP-like domain found in Thermus thermophilus TTHA0227, Acidothermus cellulolyticus ACEL2062 and similar proteins; Region: MMP_TTHA0227_like; cd12927
709991007404	Domain of unknown function (DUF4302); Region: DUF4302; pfam14135
709991007405	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
709991007406	Interdomain contacts; other site
709991007407	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
709991007408	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
709991007409	G1 box; other site
709991007410	putative GEF interaction site [polypeptide binding]; other site
709991007411	GTP/Mg2+ binding site [chemical binding]; other site
709991007412	Switch I region; other site
709991007413	G2 box; other site
709991007414	G3 box; other site
709991007415	Switch II region; other site
709991007416	G4 box; other site
709991007417	G5 box; other site
709991007418	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
709991007419	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
709991007420	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
709991007421	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
709991007422	intersubunit interface [polypeptide binding]; other site
709991007423	active site
709991007424	zinc binding site [ion binding]; other site
709991007425	Na+ binding site [ion binding]; other site
709991007426	S-adenosylmethionine-dependent methyltransferase; Region: Methyltrans_SAM; pfam10672
709991007427	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991007428	TPR motif; other site
709991007429	binding surface
709991007430	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
709991007431	ligand binding site [chemical binding]; other site
709991007432	active site
709991007433	UGI interface [polypeptide binding]; other site
709991007434	catalytic site [active]
709991007435	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
709991007436	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
709991007437	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
709991007438	active site
709991007439	HIGH motif; other site
709991007440	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
709991007441	KMSKS motif; other site
709991007442	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
709991007443	tRNA binding surface [nucleotide binding]; other site
709991007444	anticodon binding site; other site
709991007445	threonine dehydratase; Validated; Region: PRK08639
709991007446	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
709991007447	tetramer interface [polypeptide binding]; other site
709991007448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991007449	catalytic residue [active]
709991007450	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
709991007451	putative Ile/Val binding site [chemical binding]; other site
709991007452	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
709991007453	tartrate dehydrogenase; Region: TTC; TIGR02089
709991007454	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
709991007455	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
709991007456	substrate binding site [chemical binding]; other site
709991007457	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
709991007458	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
709991007459	substrate binding site [chemical binding]; other site
709991007460	ligand binding site [chemical binding]; other site
709991007461	2-isopropylmalate synthase; Validated; Region: PRK00915
709991007462	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
709991007463	active site
709991007464	catalytic residues [active]
709991007465	metal binding site [ion binding]; metal-binding site
709991007466	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
709991007467	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
709991007468	ketol-acid reductoisomerase; Region: ilvC; TIGR00465
709991007469	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
709991007470	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
709991007471	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
709991007472	putative valine binding site [chemical binding]; other site
709991007473	dimer interface [polypeptide binding]; other site
709991007474	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
709991007475	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
709991007476	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
709991007477	PYR/PP interface [polypeptide binding]; other site
709991007478	dimer interface [polypeptide binding]; other site
709991007479	TPP binding site [chemical binding]; other site
709991007480	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
709991007481	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
709991007482	TPP-binding site [chemical binding]; other site
709991007483	dimer interface [polypeptide binding]; other site
709991007484	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
709991007485	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
709991007486	putative active site [active]
709991007487	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
709991007488	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
709991007489	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
709991007490	acyl-activating enzyme (AAE) consensus motif; other site
709991007491	acyl-activating enzyme (AAE) consensus motif; other site
709991007492	putative AMP binding site [chemical binding]; other site
709991007493	putative active site [active]
709991007494	putative CoA binding site [chemical binding]; other site
709991007495	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional; Region: PRK02048
709991007496	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
709991007497	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
709991007498	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991007499	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
709991007500	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
709991007501	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991007502	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991007503	ATP binding site [chemical binding]; other site
709991007504	Mg2+ binding site [ion binding]; other site
709991007505	G-X-G motif; other site
709991007506	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991007507	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991007508	active site
709991007509	phosphorylation site [posttranslational modification]
709991007510	intermolecular recognition site; other site
709991007511	dimerization interface [polypeptide binding]; other site
709991007512	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
709991007513	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
709991007514	Protein of unknown function, DUF481; Region: DUF481; cl01213
709991007515	Predicted membrane protein [Function unknown]; Region: COG2261
709991007516	GGGtGRT protein; Region: GGGtGRT; pfam14057
709991007517	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
709991007518	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
709991007519	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
709991007520	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
709991007521	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
709991007522	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
709991007523	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991007524	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991007525	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
709991007526	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
709991007527	Predicted membrane protein [Function unknown]; Region: COG2259
709991007528	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991007529	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
709991007530	substrate binding site [chemical binding]; other site
709991007531	nucleotide binding site [chemical binding]; other site
709991007532	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
709991007533	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
709991007534	dimer interface [polypeptide binding]; other site
709991007535	active site
709991007536	metal binding site [ion binding]; metal-binding site
709991007537	glutathione binding site [chemical binding]; other site
709991007538	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
709991007539	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
709991007540	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
709991007541	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991007542	Walker A/P-loop; other site
709991007543	ATP binding site [chemical binding]; other site
709991007544	Q-loop/lid; other site
709991007545	ABC transporter signature motif; other site
709991007546	Walker B; other site
709991007547	D-loop; other site
709991007548	H-loop/switch region; other site
709991007549	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
709991007550	active site
709991007551	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991007552	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991007553	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991007554	DNA binding residues [nucleotide binding]
709991007555	FecR protein; Region: FecR; pfam04773
709991007556	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991007557	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991007558	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991007559	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991007560	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991007561	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991007562	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991007563	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991007564	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
709991007565	active site
709991007566	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
709991007567	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991007568	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991007569	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991007570	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991007571	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991007572	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991007573	FecR protein; Region: FecR; pfam04773
709991007574	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991007575	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991007576	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991007577	DNA binding residues [nucleotide binding]
709991007578	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
709991007579	RNA/DNA hybrid binding site [nucleotide binding]; other site
709991007580	active site
709991007581	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
709991007582	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
709991007583	NAD(P) binding site [chemical binding]; other site
709991007584	active site
709991007585	ribonuclease R; Region: RNase_R; TIGR02063
709991007586	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
709991007587	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
709991007588	RNB domain; Region: RNB; pfam00773
709991007589	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
709991007590	RNA binding site [nucleotide binding]; other site
709991007591	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
709991007592	Carbon starvation protein CstA; Region: CstA; pfam02554
709991007593	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
709991007594	putative peptidase; Provisional; Region: PRK11649
709991007595	Peptidase family M23; Region: Peptidase_M23; pfam01551
709991007596	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
709991007597	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
709991007598	metal ion-dependent adhesion site (MIDAS); other site
709991007599	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991007600	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991007601	catalytic residues [active]
709991007602	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
709991007603	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
709991007604	active site
709991007605	PHP Thumb interface [polypeptide binding]; other site
709991007606	metal binding site [ion binding]; metal-binding site
709991007607	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
709991007608	generic binding surface I; other site
709991007609	generic binding surface II; other site
709991007610	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
709991007611	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
709991007612	active site
709991007613	substrate binding site [chemical binding]; other site
709991007614	cosubstrate binding site; other site
709991007615	catalytic site [active]
709991007616	acyl carrier protein; Provisional; Region: acpP; PRK00982
709991007617	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
709991007618	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
709991007619	dimer interface [polypeptide binding]; other site
709991007620	active site
709991007621	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
709991007622	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
709991007623	dimerization interface [polypeptide binding]; other site
709991007624	active site
709991007625	metal binding site [ion binding]; metal-binding site
709991007626	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
709991007627	dsRNA binding site [nucleotide binding]; other site
709991007628	elongation factor P; Validated; Region: PRK00529
709991007629	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
709991007630	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
709991007631	RNA binding site [nucleotide binding]; other site
709991007632	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
709991007633	RNA binding site [nucleotide binding]; other site
709991007634	RDD family; Region: RDD; pfam06271
709991007635	Integral membrane protein DUF95; Region: DUF95; pfam01944
709991007636	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
709991007637	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
709991007638	MoxR-like ATPases [General function prediction only]; Region: COG0714
709991007639	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991007640	Walker A motif; other site
709991007641	ATP binding site [chemical binding]; other site
709991007642	Walker B motif; other site
709991007643	arginine finger; other site
709991007644	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
709991007645	Protein of unknown function DUF58; Region: DUF58; pfam01882
709991007646	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991007647	H+ Antiporter protein; Region: 2A0121; TIGR00900
709991007648	putative substrate translocation pore; other site
709991007649	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
709991007650	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
709991007651	Uncharacterized protein conserved in bacteria (DUF2059); Region: DUF2059; pfam09832
709991007652	DNA topoisomerase III; Provisional; Region: PRK07726
709991007653	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
709991007654	active site
709991007655	putative interdomain interaction site [polypeptide binding]; other site
709991007656	putative metal-binding site [ion binding]; other site
709991007657	putative nucleotide binding site [chemical binding]; other site
709991007658	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
709991007659	domain I; other site
709991007660	DNA binding groove [nucleotide binding]
709991007661	phosphate binding site [ion binding]; other site
709991007662	domain II; other site
709991007663	domain III; other site
709991007664	nucleotide binding site [chemical binding]; other site
709991007665	catalytic site [active]
709991007666	domain IV; other site
709991007667	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
709991007668	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
709991007669	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
709991007670	catalytic residues [active]
709991007671	catalytic nucleophile [active]
709991007672	Presynaptic Site I dimer interface [polypeptide binding]; other site
709991007673	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
709991007674	Synaptic Flat tetramer interface [polypeptide binding]; other site
709991007675	Synaptic Site I dimer interface [polypeptide binding]; other site
709991007676	DNA binding site [nucleotide binding]
709991007677	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
709991007678	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
709991007679	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
709991007680	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
709991007681	inhibitor-cofactor binding pocket; inhibition site
709991007682	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991007683	catalytic residue [active]
709991007684	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
709991007685	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
709991007686	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
709991007687	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
709991007688	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
709991007689	classical (c) SDRs; Region: SDR_c; cd05233
709991007690	NAD(P) binding site [chemical binding]; other site
709991007691	active site
709991007692	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
709991007693	AMP-binding enzyme; Region: AMP-binding; pfam00501
709991007694	acyl-activating enzyme (AAE) consensus motif; other site
709991007695	AMP binding site [chemical binding]; other site
709991007696	active site
709991007697	CoA binding site [chemical binding]; other site
709991007698	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
709991007699	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
709991007700	Coenzyme A binding pocket [chemical binding]; other site
709991007701	Phosphopantetheine attachment site; Region: PP-binding; cl09936
709991007702	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK12880
709991007703	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
709991007704	active site
709991007705	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
709991007706	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
709991007707	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991007708	active site
709991007709	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
709991007710	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991007711	active site
709991007712	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991007713	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
709991007714	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
709991007715	NAD(P) binding site [chemical binding]; other site
709991007716	active site
709991007717	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
709991007718	active site
709991007719	NTP binding site [chemical binding]; other site
709991007720	metal binding triad [ion binding]; metal-binding site
709991007721	antibiotic binding site [chemical binding]; other site
709991007722	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
709991007723	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
709991007724	substrate binding site; other site
709991007725	tetramer interface; other site
709991007726	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
709991007727	active site
709991007728	NTP binding site [chemical binding]; other site
709991007729	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
709991007730	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
709991007731	metal binding triad [ion binding]; metal-binding site
709991007732	HEPN domain; Region: HEPN; cl00824
709991007733	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
709991007734	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
709991007735	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
709991007736	NAD binding site [chemical binding]; other site
709991007737	substrate binding site [chemical binding]; other site
709991007738	homodimer interface [polypeptide binding]; other site
709991007739	active site
709991007740	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
709991007741	transcriptional activator RfaH; Region: RfaH; TIGR01955
709991007742	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
709991007743	heterodimer interface [polypeptide binding]; other site
709991007744	homodimer interface [polypeptide binding]; other site
709991007745	Archaeal ATPase; Region: Arch_ATPase; pfam01637
709991007746	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
709991007747	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
709991007748	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
709991007749	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
709991007750	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
709991007751	active site
709991007752	homodimer interface [polypeptide binding]; other site
709991007753	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
709991007754	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
709991007755	NAD(P) binding site [chemical binding]; other site
709991007756	homodimer interface [polypeptide binding]; other site
709991007757	substrate binding site [chemical binding]; other site
709991007758	active site
709991007759	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
709991007760	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
709991007761	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
709991007762	inhibitor-cofactor binding pocket; inhibition site
709991007763	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991007764	catalytic residue [active]
709991007765	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
709991007766	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
709991007767	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991007768	catalytic residue [active]
709991007769	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
709991007770	putative trimer interface [polypeptide binding]; other site
709991007771	putative CoA binding site [chemical binding]; other site
709991007772	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
709991007773	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
709991007774	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
709991007775	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
709991007776	trimer interface [polypeptide binding]; other site
709991007777	active site
709991007778	substrate binding site [chemical binding]; other site
709991007779	CoA binding site [chemical binding]; other site
709991007780	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
709991007781	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
709991007782	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991007783	catalytic residue [active]
709991007784	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
709991007785	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991007786	active site
709991007787	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
709991007788	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u8; cd10932
709991007789	NodB motif; other site
709991007790	putative active site [active]
709991007791	putative catalytic site [active]
709991007792	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
709991007793	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
709991007794	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
709991007795	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991007796	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
709991007797	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991007798	active site
709991007799	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991007800	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991007801	active site
709991007802	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
709991007803	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
709991007804	transcriptional activator RfaH; Region: RfaH; TIGR01955
709991007805	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
709991007806	heterodimer interface [polypeptide binding]; other site
709991007807	homodimer interface [polypeptide binding]; other site
709991007808	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991007809	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991007810	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991007811	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991007812	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991007813	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991007814	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
709991007815	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991007816	catalytic residue [active]
709991007817	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991007818	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991007819	catalytic residues [active]
709991007820	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
709991007821	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991007822	motif II; other site
709991007823	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
709991007824	putative active site [active]
709991007825	putative metal binding residues [ion binding]; other site
709991007826	signature motif; other site
709991007827	putative dimer interface [polypeptide binding]; other site
709991007828	putative phosphate binding site [ion binding]; other site
709991007829	Zinc finger domain containing protein (CDGSH-type) [Function unknown]; Region: COG3369
709991007830	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
709991007831	Protein of unknown function (DUF1271); Region: DUF1271; cl01443
709991007832	CDGSH-type zinc finger. Function unknown; Region: ZnF_CDGSH; smart00704
709991007833	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
709991007834	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991007835	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991007836	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991007837	catalytic residues [active]
709991007838	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991007839	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991007840	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991007841	catalytic residues [active]
709991007842	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991007843	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991007844	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991007845	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991007846	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991007847	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
709991007848	FecR protein; Region: FecR; pfam04773
709991007849	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991007850	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991007851	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991007852	DNA binding residues [nucleotide binding]
709991007853	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
709991007854	Repair protein; Region: Repair_PSII; pfam04536
709991007855	Repair protein; Region: Repair_PSII; pfam04536
709991007856	LemA family; Region: LemA; pfam04011
709991007857	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
709991007858	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
709991007859	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
709991007860	Protein of unknown function (DUF3137); Region: DUF3137; pfam11335
709991007861	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
709991007862	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
709991007863	hypothetical protein; Provisional; Region: PRK11770
709991007864	Domain of unknown function (DUF307); Region: DUF307; pfam03733
709991007865	Domain of unknown function (DUF307); Region: DUF307; pfam03733
709991007866	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
709991007867	active site
709991007868	Uncharacterized conserved protein [Function unknown]; Region: COG2006
709991007869	Domain of unknown function (DUF362); Region: DUF362; pfam04015
709991007870	4Fe-4S binding domain; Region: Fer4_5; pfam12801
709991007871	4Fe-4S binding domain; Region: Fer4_5; pfam12801
709991007872	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
709991007873	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
709991007874	ferredoxin-type protein NapF; Region: napF; TIGR00402
709991007875	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
709991007876	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
709991007877	putative transporter; Provisional; Region: PRK11660
709991007878	Sulfate transporter family; Region: Sulfate_transp; pfam00916
709991007879	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
709991007880	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991007881	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
709991007882	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
709991007883	amidophosphoribosyltransferase; Region: purF; TIGR01134
709991007884	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
709991007885	active site
709991007886	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
709991007887	active site
709991007888	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991007889	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991007890	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991007891	DNA binding residues [nucleotide binding]
709991007892	FecR protein; Region: FecR; pfam04773
709991007893	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991007894	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991007895	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991007896	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991007897	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991007898	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991007899	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991007900	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991007901	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
709991007902	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
709991007903	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
709991007904	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
709991007905	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
709991007906	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
709991007907	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
709991007908	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
709991007909	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
709991007910	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
709991007911	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
709991007912	Domain of unknown function DUF20; Region: UPF0118; pfam01594
709991007913	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
709991007914	Found in ATP-dependent protease La (LON); Region: LON; smart00464
709991007915	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991007916	Walker A motif; other site
709991007917	ATP binding site [chemical binding]; other site
709991007918	Walker B motif; other site
709991007919	arginine finger; other site
709991007920	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
709991007921	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
709991007922	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
709991007923	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
709991007924	LrgA family; Region: LrgA; pfam03788
709991007925	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
709991007926	purine nucleoside phosphorylase; Provisional; Region: PRK08202
709991007927	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
709991007928	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
709991007929	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
709991007930	tandem repeat interface [polypeptide binding]; other site
709991007931	oligomer interface [polypeptide binding]; other site
709991007932	active site residues [active]
709991007933	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
709991007934	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
709991007935	tandem repeat interface [polypeptide binding]; other site
709991007936	oligomer interface [polypeptide binding]; other site
709991007937	active site residues [active]
709991007938	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
709991007939	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
709991007940	hinge; other site
709991007941	active site
709991007942	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
709991007943	catalytic center binding site [active]
709991007944	ATP binding site [chemical binding]; other site
709991007945	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
709991007946	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
709991007947	Part of AAA domain; Region: AAA_19; pfam13245
709991007948	Family description; Region: UvrD_C_2; pfam13538
709991007949	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
709991007950	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991007951	TPR motif; other site
709991007952	TPR repeat; Region: TPR_11; pfam13414
709991007953	binding surface
709991007954	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
709991007955	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991007956	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
709991007957	KilA-N domain; Region: KilA-N; pfam04383
709991007958	reverse gyrase; Region: rgy; TIGR01054
709991007959	AAA domain; Region: AAA_22; pfam13401
709991007960	AAA ATPase domain; Region: AAA_16; pfam13191
709991007961	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
709991007962	HAMP domain; Region: HAMP; pfam00672
709991007963	dimerization interface [polypeptide binding]; other site
709991007964	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
709991007965	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991007966	dimer interface [polypeptide binding]; other site
709991007967	phosphorylation site [posttranslational modification]
709991007968	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991007969	ATP binding site [chemical binding]; other site
709991007970	Mg2+ binding site [ion binding]; other site
709991007971	G-X-G motif; other site
709991007972	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
709991007973	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
709991007974	putative active site [active]
709991007975	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
709991007976	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
709991007977	metal binding site [ion binding]; metal-binding site
709991007978	dimer interface [polypeptide binding]; other site
709991007979	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991007980	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991007981	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
709991007982	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
709991007983	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
709991007984	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
709991007985	NAD binding site [chemical binding]; other site
709991007986	homodimer interface [polypeptide binding]; other site
709991007987	active site
709991007988	substrate binding site [chemical binding]; other site
709991007989	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
709991007990	hypothetical protein; Reviewed; Region: PRK12497
709991007991	OsmC-like protein; Region: OsmC; pfam02566
709991007992	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
709991007993	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
709991007994	NAD(P) binding site [chemical binding]; other site
709991007995	active site
709991007996	peptide chain release factor 1; Validated; Region: prfA; PRK00591
709991007997	This domain is found in peptide chain release factors; Region: PCRF; smart00937
709991007998	RF-1 domain; Region: RF-1; pfam00472
709991007999	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
709991008000	active site
709991008001	dimer interface [polypeptide binding]; other site
709991008002	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
709991008003	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991008004	active site
709991008005	motif I; other site
709991008006	motif II; other site
709991008007	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
709991008008	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
709991008009	dimer interface [polypeptide binding]; other site
709991008010	pyridoxal binding site [chemical binding]; other site
709991008011	ATP binding site [chemical binding]; other site
709991008012	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
709991008013	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
709991008014	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
709991008015	MutS domain III; Region: MutS_III; pfam05192
709991008016	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991008017	Walker A/P-loop; other site
709991008018	ATP binding site [chemical binding]; other site
709991008019	Q-loop/lid; other site
709991008020	ABC transporter signature motif; other site
709991008021	Walker B; other site
709991008022	D-loop; other site
709991008023	H-loop/switch region; other site
709991008024	MutS domain III; Region: MutS_III; pfam05192
709991008025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991008026	Walker A/P-loop; other site
709991008027	ATP binding site [chemical binding]; other site
709991008028	Q-loop/lid; other site
709991008029	ABC transporter signature motif; other site
709991008030	Walker B; other site
709991008031	D-loop; other site
709991008032	H-loop/switch region; other site
709991008033	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
709991008034	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
709991008035	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
709991008036	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
709991008037	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991008038	Walker A/P-loop; other site
709991008039	ATP binding site [chemical binding]; other site
709991008040	Q-loop/lid; other site
709991008041	ABC transporter signature motif; other site
709991008042	Walker B; other site
709991008043	D-loop; other site
709991008044	H-loop/switch region; other site
709991008045	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991008046	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991008047	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
709991008048	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991008049	Walker A motif; other site
709991008050	ATP binding site [chemical binding]; other site
709991008051	Walker B motif; other site
709991008052	arginine finger; other site
709991008053	Homeodomain-like domain; Region: HTH_23; pfam13384
709991008054	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
709991008055	Integrase core domain; Region: rve; pfam00665
709991008056	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
709991008057	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
709991008058	Transposase [DNA replication, recombination, and repair]; Region: COG5421
709991008059	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
709991008060	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991008061	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991008062	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008063	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991008064	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008065	Domain of unknown function (DUF4268); Region: DUF4268; pfam14088
709991008066	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
709991008067	RNA/DNA hybrid binding site [nucleotide binding]; other site
709991008068	active site
709991008069	GH3 auxin-responsive promoter; Region: GH3; pfam03321
709991008070	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
709991008071	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
709991008072	active site
709991008073	metal binding site [ion binding]; metal-binding site
709991008074	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991008075	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008076	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008077	DNA binding residues [nucleotide binding]
709991008078	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991008079	FecR protein; Region: FecR; pfam04773
709991008080	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991008081	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991008082	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008083	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991008084	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008085	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991008086	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991008087	SusD family; Region: SusD; pfam07980
709991008088	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
709991008089	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
709991008090	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
709991008091	active site 2 [active]
709991008092	active site 1 [active]
709991008093	Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853
709991008094	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
709991008095	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cd05188
709991008096	NAD(P) binding site [chemical binding]; other site
709991008097	lysine-2,3-aminomutase; Region: lys_2_3_AblA; TIGR03820
709991008098	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991008099	FeS/SAM binding site; other site
709991008100	Lysine-2,3-aminomutase; Region: LAM_C; pfam12544
709991008101	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991008102	Walker A/P-loop; other site
709991008103	ATP binding site [chemical binding]; other site
709991008104	Q-loop/lid; other site
709991008105	ABC transporter signature motif; other site
709991008106	Walker B; other site
709991008107	D-loop; other site
709991008108	H-loop/switch region; other site
709991008109	D-Lysine 5,6-aminomutase alpha subunit; Region: Lys-AminoMut_A; pfam09043
709991008110	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
709991008111	B12 binding domain (B12-BD). This domain binds different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide, it is found in several enzymes, such as glutamate mutase, methionine synthase...; Region: B12-binding; cd02067
709991008112	B12 binding site [chemical binding]; other site
709991008113	cobalt ligand [ion binding]; other site
709991008114	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
709991008115	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
709991008116	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
709991008117	FAD binding site [chemical binding]; other site
709991008118	homotetramer interface [polypeptide binding]; other site
709991008119	substrate binding pocket [chemical binding]; other site
709991008120	catalytic base [active]
709991008121	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
709991008122	Ligand binding site [chemical binding]; other site
709991008123	Electron transfer flavoprotein domain; Region: ETF; pfam01012
709991008124	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
709991008125	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
709991008126	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
709991008127	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
709991008128	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
709991008129	substrate binding site [chemical binding]; other site
709991008130	oxyanion hole (OAH) forming residues; other site
709991008131	trimer interface [polypeptide binding]; other site
709991008132	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
709991008133	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
709991008134	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
709991008135	hypothetical protein; Provisional; Region: PRK12705
709991008136	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991008137	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008138	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008139	DNA binding residues [nucleotide binding]
709991008140	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991008141	FecR protein; Region: FecR; pfam04773
709991008142	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008143	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008144	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
709991008145	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991008146	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991008147	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991008148	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991008149	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991008150	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991008151	HEAT repeats; Region: HEAT_2; pfam13646
709991008152	HEAT repeats; Region: HEAT_2; pfam13646
709991008153	HEAT repeats; Region: HEAT_2; pfam13646
709991008154	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991008155	catalytic residues [active]
709991008156	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991008157	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991008158	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991008159	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991008160	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008161	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991008162	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008163	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991008164	FecR protein; Region: FecR; pfam04773
709991008165	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991008166	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008167	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008168	DNA binding residues [nucleotide binding]
709991008169	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
709991008170	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
709991008171	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
709991008172	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
709991008173	TPP-binding site [chemical binding]; other site
709991008174	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
709991008175	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
709991008176	dimer interface [polypeptide binding]; other site
709991008177	PYR/PP interface [polypeptide binding]; other site
709991008178	TPP binding site [chemical binding]; other site
709991008179	substrate binding site [chemical binding]; other site
709991008180	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
709991008181	4Fe-4S binding domain; Region: Fer4; cl02805
709991008182	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
709991008183	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991008184	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
709991008185	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991008186	homodimer interface [polypeptide binding]; other site
709991008187	catalytic residue [active]
709991008188	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
709991008189	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
709991008190	FtsX-like permease family; Region: FtsX; pfam02687
709991008191	Gram-negative bacterial tonB protein; Region: TonB; cl10048
709991008192	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cd00413
709991008193	active site
709991008194	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
709991008195	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
709991008196	active site
709991008197	Bacterial Ig-like domain; Region: Big_5; pfam13205
709991008198	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
709991008199	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; cl01930
709991008200	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
709991008201	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
709991008202	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
709991008203	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
709991008204	active site
709991008205	NTP binding site [chemical binding]; other site
709991008206	metal binding triad [ion binding]; metal-binding site
709991008207	antibiotic binding site [chemical binding]; other site
709991008208	Protein of unknown function DUF86; Region: DUF86; cl01031
709991008209	Phosphoribosylaminoimidazole (AIR) synthetase [Nucleotide transport and metabolism]; Region: PurM; COG0150
709991008210	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
709991008211	dimerization interface [polypeptide binding]; other site
709991008212	ATP binding site [chemical binding]; other site
709991008213	Uncharacterized conserved protein [Function unknown]; Region: COG2128
709991008214	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
709991008215	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
709991008216	Ferritin-like domain; Region: Ferritin; pfam00210
709991008217	ferroxidase diiron center [ion binding]; other site
709991008218	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
709991008219	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
709991008220	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
709991008221	Bacitracin resistance protein BacA; Region: BacA; pfam02673
709991008222	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
709991008223	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
709991008224	RNA binding site [nucleotide binding]; other site
709991008225	active site
709991008226	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
709991008227	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
709991008228	Peptidase family M48; Region: Peptidase_M48; pfam01435
709991008229	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
709991008230	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
709991008231	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991008232	catalytic residue [active]
709991008233	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
709991008234	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
709991008235	Flavoprotein; Region: Flavoprotein; pfam02441
709991008236	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
709991008237	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
709991008238	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
709991008239	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
709991008240	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
709991008241	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
709991008242	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
709991008243	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
709991008244	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
709991008245	ligand binding site [chemical binding]; other site
709991008246	acyl-CoA esterase; Provisional; Region: PRK10673
709991008247	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
709991008248	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
709991008249	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
709991008250	L-aspartate oxidase; Provisional; Region: PRK06175
709991008251	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
709991008252	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
709991008253	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
709991008254	putative Iron-sulfur protein interface [polypeptide binding]; other site
709991008255	proximal heme binding site [chemical binding]; other site
709991008256	distal heme binding site [chemical binding]; other site
709991008257	putative dimer interface [polypeptide binding]; other site
709991008258	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
709991008259	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
709991008260	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
709991008261	Beta-lactamase; Region: Beta-lactamase; cl17358
709991008262	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991008263	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008264	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008265	catalytic residues [active]
709991008266	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
709991008267	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991008268	binding surface
709991008269	TPR repeat; Region: TPR_11; pfam13414
709991008270	TPR motif; other site
709991008271	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991008272	TPR repeat; Region: TPR_11; pfam13414
709991008273	binding surface
709991008274	TPR motif; other site
709991008275	TPR repeat; Region: TPR_11; pfam13414
709991008276	TPR repeat; Region: TPR_11; pfam13414
709991008277	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991008278	TPR motif; other site
709991008279	binding surface
709991008280	TPR repeat; Region: TPR_11; pfam13414
709991008281	TPR repeat; Region: TPR_11; pfam13414
709991008282	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991008283	binding surface
709991008284	TPR motif; other site
709991008285	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991008286	TPR motif; other site
709991008287	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991008288	binding surface
709991008289	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
709991008290	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
709991008291	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991008292	catalytic residue [active]
709991008293	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
709991008294	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
709991008295	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
709991008296	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
709991008297	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
709991008298	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
709991008299	active site
709991008300	ADP/pyrophosphate binding site [chemical binding]; other site
709991008301	dimerization interface [polypeptide binding]; other site
709991008302	allosteric effector site; other site
709991008303	fructose-1,6-bisphosphate binding site; other site
709991008304	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991008305	active site
709991008306	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
709991008307	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008308	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008309	DNA binding residues [nucleotide binding]
709991008310	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008311	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
709991008312	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
709991008313	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
709991008314	active site
709991008315	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
709991008316	Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins; Region: SRPBCC_Aha1; cd08892
709991008317	putative hydrophobic ligand binding site [chemical binding]; other site
709991008318	putative Hsp90 binding residues [polypeptide binding]; other site
709991008319	S4 domain; Region: S4_2; pfam13275
709991008320	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
709991008321	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
709991008322	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
709991008323	active site
709991008324	catalytic tetrad [active]
709991008325	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991008326	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008327	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008328	DNA binding residues [nucleotide binding]
709991008329	FecR protein; Region: FecR; pfam04773
709991008330	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008331	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008332	catalytic residues [active]
709991008333	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991008334	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008335	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008336	catalytic residues [active]
709991008337	Eukaryotic phosphomannomutase; Region: PMM; cl17107
709991008338	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
709991008339	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
709991008340	motif II; other site
709991008341	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
709991008342	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
709991008343	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
709991008344	thiamine-monophosphate kinase; Region: thiL; TIGR01379
709991008345	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
709991008346	ATP binding site [chemical binding]; other site
709991008347	dimerization interface [polypeptide binding]; other site
709991008348	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
709991008349	putative ABC transporter; Region: ycf24; CHL00085
709991008350	FeS assembly ATPase SufC; Region: sufC; TIGR01978
709991008351	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
709991008352	Walker A/P-loop; other site
709991008353	ATP binding site [chemical binding]; other site
709991008354	Q-loop/lid; other site
709991008355	ABC transporter signature motif; other site
709991008356	Walker B; other site
709991008357	D-loop; other site
709991008358	H-loop/switch region; other site
709991008359	FeS assembly protein SufD; Region: sufD; TIGR01981
709991008360	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
709991008361	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
709991008362	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
709991008363	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
709991008364	catalytic residue [active]
709991008365	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
709991008366	Domain of unknown function DUF59; Region: DUF59; cl00941
709991008367	Sporulation related domain; Region: SPOR; pfam05036
709991008368	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613
709991008369	Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149
709991008370	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
709991008371	4Fe-4S binding domain; Region: Fer4; pfam00037
709991008372	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
709991008373	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
709991008374	Protein of unknown function (DUF1450); Region: DUF1450; cl11488
709991008375	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
709991008376	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
709991008377	4Fe-4S binding domain; Region: Fer4; pfam00037
709991008378	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
709991008379	Putative Fe-S cluster; Region: FeS; cl17515
709991008380	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
709991008381	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
709991008382	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
709991008383	Protein export membrane protein; Region: SecD_SecF; pfam02355
709991008384	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
709991008385	catalytic motif [active]
709991008386	Catalytic residue [active]
709991008387	malate dehydrogenase; Reviewed; Region: PRK06223
709991008388	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
709991008389	dimer interface [polypeptide binding]; other site
709991008390	NAD(P) binding site [chemical binding]; other site
709991008391	tetramer (dimer of dimers) interface [polypeptide binding]; other site
709991008392	substrate binding site [chemical binding]; other site
709991008393	aspartate aminotransferase; Provisional; Region: PRK07568
709991008394	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991008395	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991008396	homodimer interface [polypeptide binding]; other site
709991008397	catalytic residue [active]
709991008398	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
709991008399	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_1; cd13140
709991008400	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
709991008401	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
709991008402	ATP-grasp domain; Region: ATP-grasp_4; cl17255
709991008403	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
709991008404	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
709991008405	Ligand Binding Site [chemical binding]; other site
709991008406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991008407	S-adenosylmethionine binding site [chemical binding]; other site
709991008408	GldH lipoprotein; Region: GldH_lipo; pfam14109
709991008409	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
709991008410	dimer interface [polypeptide binding]; other site
709991008411	catalytic triad [active]
709991008412	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
709991008413	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
709991008414	active site
709991008415	HIGH motif; other site
709991008416	KMSKS motif; other site
709991008417	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
709991008418	tRNA binding surface [nucleotide binding]; other site
709991008419	anticodon binding site; other site
709991008420	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
709991008421	dimer interface [polypeptide binding]; other site
709991008422	putative tRNA-binding site [nucleotide binding]; other site
709991008423	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008424	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008425	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
709991008426	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
709991008427	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
709991008428	active site
709991008429	metal binding site [ion binding]; metal-binding site
709991008430	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
709991008431	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
709991008432	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
709991008433	Nucleoside recognition; Region: Gate; pfam07670
709991008434	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
709991008435	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991008436	muropeptide transporter; Reviewed; Region: ampG; PRK11902
709991008437	putative substrate translocation pore; other site
709991008438	Stage II sporulation protein; Region: SpoIID; pfam08486
709991008439	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
709991008440	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
709991008441	nucleotide binding site/active site [active]
709991008442	HIT family signature motif; other site
709991008443	catalytic residue [active]
709991008444	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
709991008445	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
709991008446	active site
709991008447	RecX family; Region: RecX; pfam02631
709991008448	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
709991008449	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991008450	S-adenosylmethionine binding site [chemical binding]; other site
709991008451	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
709991008452	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
709991008453	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
709991008454	putative active site [active]
709991008455	catalytic site [active]
709991008456	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
709991008457	putative active site [active]
709991008458	catalytic site [active]
709991008459	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
709991008460	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
709991008461	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
709991008462	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
709991008463	active site
709991008464	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
709991008465	dimer interface [polypeptide binding]; other site
709991008466	substrate binding site [chemical binding]; other site
709991008467	catalytic residues [active]
709991008468	mutatrotase, YjhT family; Region: muta_rot_YjhT; TIGR03547
709991008469	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
709991008470	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
709991008471	Pathogenicity locus; Region: Cdd1; pfam11731
709991008472	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_10; cd07251
709991008473	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
709991008474	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991008475	Helix-turn-helix domain; Region: HTH_17; pfam12728
709991008476	Virulence-associated protein E; Region: VirE; pfam05272
709991008477	CHC2 zinc finger; Region: zf-CHC2; cl17510
709991008478	Toprim-like; Region: Toprim_2; pfam13155
709991008479	active site
709991008480	metal binding site [ion binding]; metal-binding site
709991008481	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
709991008482	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
709991008483	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
709991008484	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_1; cd12161
709991008485	putative ligand binding site [chemical binding]; other site
709991008486	putative NAD binding site [chemical binding]; other site
709991008487	catalytic site [active]
709991008488	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
709991008489	glycerol kinase; Provisional; Region: glpK; PRK00047
709991008490	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
709991008491	N- and C-terminal domain interface [polypeptide binding]; other site
709991008492	active site
709991008493	MgATP binding site [chemical binding]; other site
709991008494	catalytic site [active]
709991008495	metal binding site [ion binding]; metal-binding site
709991008496	glycerol binding site [chemical binding]; other site
709991008497	homotetramer interface [polypeptide binding]; other site
709991008498	homodimer interface [polypeptide binding]; other site
709991008499	FBP binding site [chemical binding]; other site
709991008500	protein IIAGlc interface [polypeptide binding]; other site
709991008501	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
709991008502	amphipathic channel; other site
709991008503	Asn-Pro-Ala signature motifs; other site
709991008504	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
709991008505	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
709991008506	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
709991008507	hypothetical protein; Validated; Region: PRK02101
709991008508	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
709991008509	hydroxyglutarate oxidase; Provisional; Region: PRK11728
709991008510	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
709991008511	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
709991008512	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
709991008513	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
709991008514	Cysteine-rich domain; Region: CCG; pfam02754
709991008515	Cysteine-rich domain; Region: CCG; pfam02754
709991008516	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
709991008517	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991008518	putative substrate translocation pore; other site
709991008519	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
709991008520	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
709991008521	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
709991008522	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
709991008523	putative substrate translocation pore; other site
709991008524	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
709991008525	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
709991008526	active site
709991008527	catalytic site [active]
709991008528	Phosphate-selective porin [Inorganic ion transport and metabolism]; Region: OprP; COG3746
709991008529	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
709991008530	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
709991008531	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
709991008532	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
709991008533	ATP binding site [chemical binding]; other site
709991008534	putative Mg++ binding site [ion binding]; other site
709991008535	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
709991008536	nucleotide binding region [chemical binding]; other site
709991008537	ATP-binding site [chemical binding]; other site
709991008538	TRCF domain; Region: TRCF; pfam03461
709991008539	Type III pantothenate kinase; Region: Pan_kinase; cl17198
709991008540	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117; cl01200
709991008541	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
709991008542	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
709991008543	Domain of unknown function DUF21; Region: DUF21; pfam01595
709991008544	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
709991008545	Transporter associated domain; Region: CorC_HlyC; smart01091
709991008546	Transposase domain (DUF772); Region: DUF772; pfam05598
709991008547	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991008548	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
709991008549	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
709991008550	Substrate binding site; other site
709991008551	Permease; Region: Permease; pfam02405
709991008552	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
709991008553	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
709991008554	Walker A/P-loop; other site
709991008555	ATP binding site [chemical binding]; other site
709991008556	Q-loop/lid; other site
709991008557	ABC transporter signature motif; other site
709991008558	Walker B; other site
709991008559	D-loop; other site
709991008560	H-loop/switch region; other site
709991008561	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
709991008562	PspC domain; Region: PspC; pfam04024
709991008563	Predicted transcriptional regulators [Transcription]; Region: COG1695
709991008564	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
709991008565	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
709991008566	phosphoglyceromutase; Provisional; Region: PRK05434
709991008567	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
709991008568	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
709991008569	active site
709991008570	NTP binding site [chemical binding]; other site
709991008571	metal binding triad [ion binding]; metal-binding site
709991008572	antibiotic binding site [chemical binding]; other site
709991008573	Protein of unknown function DUF86; Region: DUF86; cl01031
709991008574	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
709991008575	active site
709991008576	NTP binding site [chemical binding]; other site
709991008577	metal binding triad [ion binding]; metal-binding site
709991008578	antibiotic binding site [chemical binding]; other site
709991008579	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
709991008580	Predicted permeases [General function prediction only]; Region: COG0701
709991008581	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008582	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991008583	catalytic residues [active]
709991008584	Family description; Region: DsbD_2; pfam13386
709991008585	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991008586	catalytic residues [active]
709991008587	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
709991008588	dimerization interface [polypeptide binding]; other site
709991008589	putative DNA binding site [nucleotide binding]; other site
709991008590	putative Zn2+ binding site [ion binding]; other site
709991008591	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
709991008592	AAA domain; Region: AAA_14; pfam13173
709991008593	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
709991008594	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
709991008595	metal-binding site [ion binding]
709991008596	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
709991008597	Soluble P-type ATPase [General function prediction only]; Region: COG4087
709991008598	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
709991008599	metal-binding site [ion binding]
709991008600	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
709991008601	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991008602	DDE superfamily endonuclease; Region: DDE_5; pfam13546
709991008603	BRO family, N-terminal domain; Region: Bro-N; smart01040
709991008604	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
709991008605	putative FMN binding site [chemical binding]; other site
709991008606	NADPH bind site [chemical binding]; other site
709991008607	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
709991008608	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
709991008609	active site
709991008610	metal binding site [ion binding]; metal-binding site
709991008611	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
709991008612	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
709991008613	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991008614	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008615	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991008616	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991008617	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008618	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991008619	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
709991008620	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
709991008621	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991008622	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991008623	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991008624	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
709991008625	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
709991008626	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
709991008627	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
709991008628	signal recognition particle protein; Provisional; Region: PRK10867
709991008629	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
709991008630	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
709991008631	P loop; other site
709991008632	GTP binding site [chemical binding]; other site
709991008633	Signal peptide binding domain; Region: SRP_SPB; pfam02978
709991008634	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
709991008635	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
709991008636	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
709991008637	homodimer interface [polypeptide binding]; other site
709991008638	NADP binding site [chemical binding]; other site
709991008639	substrate binding site [chemical binding]; other site
709991008640	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
709991008641	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
709991008642	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
709991008643	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
709991008644	MarC family integral membrane protein; Region: MarC; pfam01914
709991008645	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991008646	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008647	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
709991008648	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
709991008649	hypothetical protein; Provisional; Region: PRK10621
709991008650	FecR protein; Region: FecR; pfam04773
709991008651	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991008652	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991008653	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008654	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991008655	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
709991008656	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008657	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991008658	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991008659	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991008660	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008661	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008662	catalytic residues [active]
709991008663	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
709991008664	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008665	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008666	catalytic residues [active]
709991008667	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991008668	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008669	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008670	DNA binding residues [nucleotide binding]
709991008671	Protein of unknown function (DUF3379); Region: DUF3379; pfam11859
709991008672	FecR protein; Region: FecR; pfam04773
709991008673	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991008674	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
709991008675	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991008676	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991008677	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991008678	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991008679	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991008680	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991008681	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991008682	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
709991008683	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008684	catalytic residues [active]
709991008685	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008686	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008687	catalytic residues [active]
709991008688	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
709991008689	FAD binding site [chemical binding]; other site
709991008690	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
709991008691	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
709991008692	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
709991008693	substrate binding pocket [chemical binding]; other site
709991008694	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
709991008695	B12 binding site [chemical binding]; other site
709991008696	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
709991008697	hypothetical protein; Provisional; Region: PRK04334
709991008698	NIL domain; Region: NIL; pfam09383
709991008699	4Fe-4S binding domain; Region: Fer4; cl02805
709991008700	Domain of unknown function DUF39; Region: DUF39; pfam01837
709991008701	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991008702	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
709991008703	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
709991008704	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
709991008705	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
709991008706	Surface antigen; Region: Bac_surface_Ag; pfam01103
709991008707	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991008708	Histidine kinase; Region: HisKA_3; pfam07730
709991008709	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991008710	ATP binding site [chemical binding]; other site
709991008711	Mg2+ binding site [ion binding]; other site
709991008712	G-X-G motif; other site
709991008713	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
709991008714	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991008715	active site
709991008716	phosphorylation site [posttranslational modification]
709991008717	intermolecular recognition site; other site
709991008718	dimerization interface [polypeptide binding]; other site
709991008719	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991008720	DNA binding residues [nucleotide binding]
709991008721	dimerization interface [polypeptide binding]; other site
709991008722	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
709991008723	NTP_transferase_like_1 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_1; cd06422
709991008724	Substrate binding site; other site
709991008725	metal-binding site
709991008726	Family of unknown function (DUF490); Region: DUF490; pfam04357
709991008727	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
709991008728	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
709991008729	Surface antigen; Region: Bac_surface_Ag; pfam01103
709991008730	DEDDy 3'-5' exonuclease domain of WRN and similar proteins; Region: WRN_exo; cd06141
709991008731	catalytic site [active]
709991008732	putative active site [active]
709991008733	putative substrate binding site [chemical binding]; other site
709991008734	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991008735	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991008736	active site
709991008737	phosphorylation site [posttranslational modification]
709991008738	dimerization interface [polypeptide binding]; other site
709991008739	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991008740	dimer interface [polypeptide binding]; other site
709991008741	phosphorylation site [posttranslational modification]
709991008742	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991008743	ATP binding site [chemical binding]; other site
709991008744	Mg2+ binding site [ion binding]; other site
709991008745	G-X-G motif; other site
709991008746	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
709991008747	GAF domain; Region: GAF; cl17456
709991008748	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
709991008749	AAA domain; Region: AAA_14; pfam13173
709991008750	Archaeal ATPase; Region: Arch_ATPase; pfam01637
709991008751	Archaea bacterial proteins of unknown function; Region: DUF234; pfam03008
709991008752	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
709991008753	Protein of unknown function; Region: DUF3971; pfam13116
709991008754	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
709991008755	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
709991008756	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
709991008757	metal-binding site [ion binding]
709991008758	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
709991008759	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
709991008760	metal-binding site [ion binding]
709991008761	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
709991008762	Soluble P-type ATPase [General function prediction only]; Region: COG4087
709991008763	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_3; cd09602
709991008764	Peptidase family M1; Region: Peptidase_M1; pfam01433
709991008765	Zn binding site [ion binding]; other site
709991008766	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
709991008767	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
709991008768	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
709991008769	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
709991008770	RNA binding site [nucleotide binding]; other site
709991008771	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
709991008772	putative metal binding site [ion binding]; other site
709991008773	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991008774	Walker A/P-loop; other site
709991008775	ATP binding site [chemical binding]; other site
709991008776	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
709991008777	Q-loop/lid; other site
709991008778	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
709991008779	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991008780	Walker A/P-loop; other site
709991008781	ATP binding site [chemical binding]; other site
709991008782	Q-loop/lid; other site
709991008783	ABC transporter signature motif; other site
709991008784	Walker B; other site
709991008785	D-loop; other site
709991008786	H-loop/switch region; other site
709991008787	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
709991008788	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
709991008789	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991008790	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
709991008791	Pollen proteins Ole e I like; Region: Pollen_Ole_e_I; pfam01190
709991008792	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
709991008793	EamA-like transporter family; Region: EamA; pfam00892
709991008794	EamA-like transporter family; Region: EamA; pfam00892
709991008795	MarC family integral membrane protein; Region: MarC; cl00919
709991008796	Predicted membrane protein [Function unknown]; Region: COG1238
709991008797	Predicted membrane protein [Function unknown]; Region: COG1238
709991008798	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
709991008799	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991008800	active site
709991008801	phosphorylation site [posttranslational modification]
709991008802	intermolecular recognition site; other site
709991008803	dimerization interface [polypeptide binding]; other site
709991008804	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
709991008805	Walker A motif; other site
709991008806	ATP binding site [chemical binding]; other site
709991008807	Walker B motif; other site
709991008808	arginine finger; other site
709991008809	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
709991008810	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991008811	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008812	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008813	catalytic residues [active]
709991008814	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991008815	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991008816	catalytic residues [active]
709991008817	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
709991008818	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
709991008819	substrate-cofactor binding pocket; other site
709991008820	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991008821	catalytic residue [active]
709991008822	Predicted peptidase [General function prediction only]; Region: COG4099
709991008823	putative transposase OrfB; Reviewed; Region: PHA02517
709991008824	HTH-like domain; Region: HTH_21; pfam13276
709991008825	Integrase core domain; Region: rve; pfam00665
709991008826	Integrase core domain; Region: rve_2; pfam13333
709991008827	Homeodomain-like domain; Region: HTH_23; cl17451
709991008828	Helix-turn-helix domain; Region: HTH_28; pfam13518
709991008829	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
709991008830	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991008831	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008832	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008833	DNA binding residues [nucleotide binding]
709991008834	NigD-like protein; Region: NigD; pfam12667
709991008835	AAA domain; Region: AAA_14; pfam13173
709991008836	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
709991008837	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991008838	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008839	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991008840	DNA binding residues [nucleotide binding]
709991008841	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
709991008842	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
709991008843	catalytic motif [active]
709991008844	Zn binding site [ion binding]; other site
709991008845	RibD C-terminal domain; Region: RibD_C; cl17279
709991008846	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
709991008847	Lumazine binding domain; Region: Lum_binding; pfam00677
709991008848	Lumazine binding domain; Region: Lum_binding; pfam00677
709991008849	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
709991008850	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
709991008851	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
709991008852	dimerization interface [polypeptide binding]; other site
709991008853	active site
709991008854	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
709991008855	homopentamer interface [polypeptide binding]; other site
709991008856	active site
709991008857	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
709991008858	dimer interface [polypeptide binding]; other site
709991008859	catalytic triad [active]
709991008860	peroxidatic and resolving cysteines [active]
709991008861	membrane protein insertase; Provisional; Region: PRK01318
709991008862	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
709991008863	CTP synthetase; Validated; Region: pyrG; PRK05380
709991008864	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
709991008865	Catalytic site [active]
709991008866	active site
709991008867	UTP binding site [chemical binding]; other site
709991008868	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
709991008869	active site
709991008870	putative oxyanion hole; other site
709991008871	catalytic triad [active]
709991008872	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
709991008873	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
709991008874	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
709991008875	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
709991008876	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
709991008877	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
709991008878	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
709991008879	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
709991008880	putative acyl-acceptor binding pocket; other site
709991008881	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
709991008882	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
709991008883	Probable Catalytic site; other site
709991008884	metal-binding site
709991008885	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
709991008886	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991008887	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991008888	DNA binding residues [nucleotide binding]
709991008889	Response regulator receiver domain; Region: Response_reg; pfam00072
709991008890	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991008891	active site
709991008892	phosphorylation site [posttranslational modification]
709991008893	intermolecular recognition site; other site
709991008894	dimerization interface [polypeptide binding]; other site
709991008895	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
709991008896	DNA binding site [nucleotide binding]
709991008897	NVEALA protein; Region: NVEALA; pfam14055
709991008898	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
709991008899	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
709991008900	dimer interface [polypeptide binding]; other site
709991008901	active site
709991008902	catalytic residue [active]
709991008903	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
709991008904	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
709991008905	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
709991008906	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
709991008907	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
709991008908	Walker A/P-loop; other site
709991008909	ATP binding site [chemical binding]; other site
709991008910	Q-loop/lid; other site
709991008911	ABC transporter signature motif; other site
709991008912	Walker B; other site
709991008913	D-loop; other site
709991008914	H-loop/switch region; other site
709991008915	NVEALA protein; Region: NVEALA; pfam14055
709991008916	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991008917	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
709991008918	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991008919	ATP binding site [chemical binding]; other site
709991008920	Mg2+ binding site [ion binding]; other site
709991008921	G-X-G motif; other site
709991008922	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
709991008923	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991008924	active site
709991008925	phosphorylation site [posttranslational modification]
709991008926	intermolecular recognition site; other site
709991008927	dimerization interface [polypeptide binding]; other site
709991008928	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
709991008929	DNA binding site [nucleotide binding]
709991008930	Transcriptional regulators [Transcription]; Region: PurR; COG1609
709991008931	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
709991008932	DNA binding site [nucleotide binding]
709991008933	domain linker motif; other site
709991008934	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
709991008935	dimerization interface [polypeptide binding]; other site
709991008936	ligand binding site [chemical binding]; other site
709991008937	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
709991008938	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
709991008939	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
709991008940	Zn2+ binding site [ion binding]; other site
709991008941	Mg2+ binding site [ion binding]; other site
709991008942	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
709991008943	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
709991008944	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
709991008945	homodecamer interface [polypeptide binding]; other site
709991008946	GTP cyclohydrolase I; Provisional; Region: PLN03044
709991008947	active site
709991008948	putative catalytic site residues [active]
709991008949	zinc binding site [ion binding]; other site
709991008950	GTP-CH-I/GFRP interaction surface; other site
709991008951	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
709991008952	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991008953	non-specific DNA binding site [nucleotide binding]; other site
709991008954	salt bridge; other site
709991008955	sequence-specific DNA binding site [nucleotide binding]; other site
709991008956	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
709991008957	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
709991008958	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
709991008959	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
709991008960	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
709991008961	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
709991008962	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
709991008963	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
709991008964	hypothetical protein; Provisional; Region: PRK13665
709991008965	diaminopimelate decarboxylase; Region: lysA; TIGR01048
709991008966	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
709991008967	active site
709991008968	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
709991008969	substrate binding site [chemical binding]; other site
709991008970	catalytic residues [active]
709991008971	dimer interface [polypeptide binding]; other site
709991008972	aspartate kinase III; Validated; Region: PRK09084
709991008973	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
709991008974	putative catalytic residues [active]
709991008975	nucleotide binding site [chemical binding]; other site
709991008976	aspartate binding site [chemical binding]; other site
709991008977	ACT domains located C-terminal to the catalytic domain of  the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC-like_1; cd04912
709991008978	dimer interface [polypeptide binding]; other site
709991008979	allosteric regulatory binding pocket; other site
709991008980	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
709991008981	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
709991008982	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991008983	S-adenosylmethionine binding site [chemical binding]; other site
709991008984	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
709991008985	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991008986	S-adenosylmethionine binding site [chemical binding]; other site
709991008987	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
709991008988	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
709991008989	FAD binding domain; Region: FAD_binding_4; pfam01565
709991008990	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
709991008991	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
709991008992	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
709991008993	active site
709991008994	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
709991008995	active site 2 [active]
709991008996	active site 1 [active]
709991008997	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
709991008998	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
709991008999	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
709991009000	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
709991009001	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
709991009002	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
709991009003	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
709991009004	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
709991009005	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
709991009006	Walker A/P-loop; other site
709991009007	ATP binding site [chemical binding]; other site
709991009008	Q-loop/lid; other site
709991009009	ABC transporter signature motif; other site
709991009010	Walker B; other site
709991009011	D-loop; other site
709991009012	H-loop/switch region; other site
709991009013	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991009014	binding surface
709991009015	TPR motif; other site
709991009016	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
709991009017	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991009018	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991009019	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991009020	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991009021	catalytic residues [active]
709991009022	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991009023	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991009024	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991009025	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991009026	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991009027	trigger factor; Region: tig; TIGR00115
709991009028	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
709991009029	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
709991009030	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
709991009031	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
709991009032	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991009033	S-adenosylmethionine binding site [chemical binding]; other site
709991009034	thymidylate synthase; Reviewed; Region: thyA; PRK01827
709991009035	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
709991009036	dimerization interface [polypeptide binding]; other site
709991009037	active site
709991009038	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
709991009039	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
709991009040	Sulfatase; Region: Sulfatase; cl17466
709991009041	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991009042	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
709991009043	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
709991009044	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
709991009045	folate binding site [chemical binding]; other site
709991009046	NADP+ binding site [chemical binding]; other site
709991009047	Lipopolysaccharide kinase (Kdo/WaaP) family; Region: Kdo; cl17488
709991009048	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
709991009049	putative metal binding site; other site
709991009050	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
709991009051	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
709991009052	serine/threonine protein kinase; Provisional; Region: PRK14879
709991009053	Lipopolysaccharide kinase (Kdo/WaaP) family; Region: Kdo; cl17488
709991009054	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
709991009055	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
709991009056	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
709991009057	active site
709991009058	metal-binding site
709991009059	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
709991009060	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
709991009061	pyridoxal 5'-phosphate binding site [chemical binding]; other site
709991009062	homodimer interface [polypeptide binding]; other site
709991009063	catalytic residue [active]
709991009064	O-Antigen ligase; Region: Wzy_C; pfam04932
709991009065	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
709991009066	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
709991009067	putative active site [active]
709991009068	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
709991009069	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
709991009070	substrate binding site; other site
709991009071	dimer interface; other site
709991009072	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
709991009073	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
709991009074	NAD binding site [chemical binding]; other site
709991009075	substrate binding site [chemical binding]; other site
709991009076	homodimer interface [polypeptide binding]; other site
709991009077	active site
709991009078	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
709991009079	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
709991009080	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
709991009081	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
709991009082	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
709991009083	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
709991009084	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
709991009085	S-adenosylmethionine binding site [chemical binding]; other site
709991009086	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
709991009087	putative metal binding site [ion binding]; other site
709991009088	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
709991009089	HSP70 interaction site [polypeptide binding]; other site
709991009090	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
709991009091	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
709991009092	CoA-binding site [chemical binding]; other site
709991009093	ATP-binding [chemical binding]; other site
709991009094	hypothetical protein; Provisional; Region: PHA02941
709991009095	Preprotein translocase subunit; Region: YajC; pfam02699
709991009096	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
709991009097	AMP nucleosidase; Provisional; Region: PRK07115
709991009098	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
709991009099	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
709991009100	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
709991009101	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991009102	binding surface
709991009103	TPR motif; other site
709991009104	membrane ATPase/protein kinase; Provisional; Region: PRK09435
709991009105	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
709991009106	Walker A; other site
709991009107	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
709991009108	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
709991009109	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
709991009110	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
709991009111	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991009112	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991009113	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991009114	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991009115	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
709991009116	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
709991009117	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
709991009118	Helix-turn-helix domain; Region: HTH_18; pfam12833
709991009119	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991009120	DDE superfamily endonuclease; Region: DDE_5; pfam13546
709991009121	Family C of G-protein coupled receptors and their close homologs, the type I periplasmic-binding proteins of ATP-binding cassette transporter-like systems; Region: PBP1_ABC_transporter_GCPR_C_like; cd04509
709991009122	Receptor family ligand binding region; Region: ANF_receptor; pfam01094
709991009123	Peptidase C13 family; Region: Peptidase_C13; pfam01650
709991009124	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
709991009125	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
709991009126	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
709991009127	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
709991009128	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
709991009129	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991009130	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991009131	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
709991009132	DNA binding residues [nucleotide binding]
709991009133	FecR protein; Region: FecR; pfam04773
709991009134	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991009135	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
709991009136	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991009137	Walker A/P-loop; other site
709991009138	ATP binding site [chemical binding]; other site
709991009139	Q-loop/lid; other site
709991009140	ABC transporter signature motif; other site
709991009141	Walker B; other site
709991009142	D-loop; other site
709991009143	H-loop/switch region; other site
709991009144	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
709991009145	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
709991009146	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
709991009147	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
709991009148	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
709991009149	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
709991009150	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991009151	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991009152	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991009153	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991009154	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991009155	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991009156	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991009157	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991009158	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991009159	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991009160	DNA binding residues [nucleotide binding]
709991009161	FecR protein; Region: FecR; pfam04773
709991009162	Secretin and TonB N terminus short domain; Region: STN; pfam07660
709991009163	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991009164	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991009165	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991009166	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991009167	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991009168	starch binding outer membrane protein SusD; Region: SusD; cd08977
709991009169	Transposase domain (DUF772); Region: DUF772; pfam05598
709991009170	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
709991009171	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
709991009172	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
709991009173	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
709991009174	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
709991009175	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
709991009176	catalytic residues [active]
709991009177	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991009178	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991009179	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991009180	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991009181	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991009182	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
709991009183	FecR protein; Region: FecR; pfam04773
709991009184	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
709991009185	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
709991009186	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
709991009187	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
709991009188	DNA binding residues [nucleotide binding]
709991009189	Transposase [DNA replication, recombination, and repair]; Region: COG5421
709991009190	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
709991009191	non-specific DNA binding site [nucleotide binding]; other site
709991009192	salt bridge; other site
709991009193	sequence-specific DNA binding site [nucleotide binding]; other site
709991009194	Helix-turn-helix domain; Region: HTH_17; cl17695
709991009195	DNA primase, catalytic core; Region: dnaG; TIGR01391
709991009196	CHC2 zinc finger; Region: zf-CHC2; cl17510
709991009197	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
709991009198	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
709991009199	active site
709991009200	metal binding site [ion binding]; metal-binding site
709991009201	interdomain interaction site; other site
709991009202	polycystin cation channel protein; Region: PCC; TIGR00864
709991009203	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991009204	Receptor L domain; Region: Recep_L_domain; pfam01030
709991009205	Uncharacterized conserved protein [Function unknown]; Region: COG3391
709991009206	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
709991009207	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991009208	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
709991009209	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
709991009210	putative ligand binding site [chemical binding]; other site
709991009211	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
709991009212	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
709991009213	dimer interface [polypeptide binding]; other site
709991009214	putative PBP binding regions; other site
709991009215	ABC-ATPase subunit  interface; other site
709991009216	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
709991009217	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
709991009218	Walker A/P-loop; other site
709991009219	ATP binding site [chemical binding]; other site
709991009220	Q-loop/lid; other site
709991009221	ABC transporter signature motif; other site
709991009222	Walker B; other site
709991009223	D-loop; other site
709991009224	H-loop/switch region; other site
709991009225	Predicted metal-binding protein (DUF2284); Region: DUF2284; cl02248
709991009226	AAA domain; Region: AAA_21; pfam13304
709991009227	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
709991009228	Walker B; other site
709991009229	D-loop; other site
709991009230	H-loop/switch region; other site
709991009231	RloB-like protein; Region: RloB; pfam13707
709991009232	Predicted metal-binding protein (DUF2284); Region: DUF2284; pfam10050
709991009233	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
709991009234	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
709991009235	Walker A/P-loop; other site
709991009236	ATP binding site [chemical binding]; other site
709991009237	Q-loop/lid; other site
709991009238	ABC transporter signature motif; other site
709991009239	Walker B; other site
709991009240	D-loop; other site
709991009241	H-loop/switch region; other site
709991009242	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
709991009243	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
709991009244	ABC-ATPase subunit  interface; other site
709991009245	dimer interface [polypeptide binding]; other site
709991009246	putative PBP binding regions; other site
709991009247	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
709991009248	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
709991009249	putative ligand binding site [chemical binding]; other site
709991009250	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
709991009251	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991009252	Uncharacterized conserved protein [Function unknown]; Region: COG3391
709991009253	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
709991009254	Receptor L domain; Region: Recep_L_domain; pfam01030
709991009255	pyruvate phosphate dikinase; Provisional; Region: PRK09279
709991009256	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
709991009257	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
709991009258	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
709991009259	MG2 domain; Region: A2M_N; pfam01835
709991009260	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
709991009261	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991009262	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
709991009263	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991009264	This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335
709991009265	putative deacylase active site [active]
709991009266	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
709991009267	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
709991009268	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
709991009269	active site
709991009270	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
709991009271	Two component regulator propeller; Region: Reg_prop; pfam07494
709991009272	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
709991009273	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
709991009274	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
709991009275	dimer interface [polypeptide binding]; other site
709991009276	phosphorylation site [posttranslational modification]
709991009277	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
709991009278	ATP binding site [chemical binding]; other site
709991009279	Mg2+ binding site [ion binding]; other site
709991009280	G-X-G motif; other site
709991009281	Response regulator receiver domain; Region: Response_reg; pfam00072
709991009282	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
709991009283	active site
709991009284	phosphorylation site [posttranslational modification]
709991009285	intermolecular recognition site; other site
709991009286	dimerization interface [polypeptide binding]; other site
709991009287	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
709991009288	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
709991009289	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
709991009290	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
709991009291	FeS/SAM binding site; other site
709991009292	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
709991009293	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
709991009294	dimer interface [polypeptide binding]; other site
709991009295	active site
709991009296	glycine loop; other site
709991009297	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
709991009298	Cna protein B-type domain; Region: Cna_B_2; pfam13715
709991009299	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
709991009300	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
709991009301	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
709991009302	starch binding outer membrane protein SusD; Region: SusD; cl17845
709991009303	SusD family; Region: SusD; pfam07980
709991009304	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
709991009305	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
709991009306	O-Antigen ligase; Region: Wzy_C; pfam04932
709991009307	Tetratricopeptide repeat; Region: TPR_12; pfam13424
709991009308	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
709991009309	binding surface
709991009310	TPR motif; other site
709991009311	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
709991009312	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
709991009313	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
709991009314	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
709991009315	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
709991009316	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
709991009317	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
709991009318	IgA Peptidase M64; Region: Peptidase_M64; pfam09471
709991009319	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
709991009320	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
709991009321	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
709991009322	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
709991009323	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
709991009324	active site
709991009325	metal binding site [ion binding]; metal-binding site
709991009326	virulence factor Mce family protein; Region: Mtu_fam_mce; TIGR00996
709991009327	mce related protein; Region: MCE; pfam02470