-- dump date   	20140619_224641
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
56110000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
56110000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
56110000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000004	Walker A motif; other site
56110000005	ATP binding site [chemical binding]; other site
56110000006	Walker B motif; other site
56110000007	arginine finger; other site
56110000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
56110000009	DnaA box-binding interface [nucleotide binding]; other site
56110000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
56110000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
56110000012	putative DNA binding surface [nucleotide binding]; other site
56110000013	dimer interface [polypeptide binding]; other site
56110000014	beta-clamp/clamp loader binding surface; other site
56110000015	beta-clamp/translesion DNA polymerase binding surface; other site
56110000016	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
56110000017	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
56110000018	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
56110000019	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
56110000020	Predicted integral membrane protein [Function unknown]; Region: COG0762
56110000021	Photosystem II reaction centre X protein (PsbX); Region: PsbX; pfam06596
56110000022	Ycf66 protein N-terminus; Region: Ycf66_N; pfam07444
56110000023	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
56110000024	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
56110000025	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
56110000026	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
56110000027	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
56110000028	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
56110000029	Transposase domain (DUF772); Region: DUF772; pfam05598
56110000030	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
56110000031	TPR repeat; Region: TPR_11; pfam13414
56110000032	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000033	TPR motif; other site
56110000034	binding surface
56110000035	TPR repeat; Region: TPR_11; pfam13414
56110000036	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000037	binding surface
56110000038	TPR motif; other site
56110000039	TPR repeat; Region: TPR_11; pfam13414
56110000040	CHAT domain; Region: CHAT; pfam12770
56110000041	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
56110000042	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
56110000043	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
56110000044	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
56110000045	trimer interface [polypeptide binding]; other site
56110000046	active site
56110000047	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
56110000048	catalytic site [active]
56110000049	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
56110000050	Alpha-amylase/alpha-mannosidase [Carbohydrate transport and metabolism]; Region: COG1449
56110000051	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
56110000052	N-terminal catalytic domain of thermoactive amylopullulanases; glycoside hydrolase family 57 (GH57); Region: GH57N_APU; cd10796
56110000053	putative active site [active]
56110000054	catalytic site [active]
56110000055	NifU-like domain; Region: NifU; pfam01106
56110000056	Protein of unknown function (DUF3386); Region: DUF3386; pfam11866
56110000057	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110000058	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110000059	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110000060	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110000061	dimer interface [polypeptide binding]; other site
56110000062	phosphorylation site [posttranslational modification]
56110000063	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110000064	ATP binding site [chemical binding]; other site
56110000065	Mg2+ binding site [ion binding]; other site
56110000066	G-X-G motif; other site
56110000067	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
56110000068	putative active site [active]
56110000069	heme pocket [chemical binding]; other site
56110000070	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110000071	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110000072	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110000073	dimer interface [polypeptide binding]; other site
56110000074	phosphorylation site [posttranslational modification]
56110000075	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110000076	ATP binding site [chemical binding]; other site
56110000077	Mg2+ binding site [ion binding]; other site
56110000078	G-X-G motif; other site
56110000079	GTP-binding protein LepA; Provisional; Region: PRK05433
56110000080	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
56110000081	G1 box; other site
56110000082	putative GEF interaction site [polypeptide binding]; other site
56110000083	GTP/Mg2+ binding site [chemical binding]; other site
56110000084	Switch I region; other site
56110000085	G2 box; other site
56110000086	G3 box; other site
56110000087	Switch II region; other site
56110000088	G4 box; other site
56110000089	G5 box; other site
56110000090	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
56110000091	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
56110000092	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
56110000093	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110000094	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
56110000095	NAD binding site [chemical binding]; other site
56110000096	putative substrate binding site 2 [chemical binding]; other site
56110000097	putative substrate binding site 1 [chemical binding]; other site
56110000098	active site
56110000099	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
56110000100	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
56110000101	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
56110000102	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
56110000103	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
56110000104	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
56110000105	Chromate transporter; Region: Chromate_transp; pfam02417
56110000106	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
56110000107	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
56110000108	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
56110000109	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR6; cd08272
56110000110	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
56110000111	putative NAD(P) binding site [chemical binding]; other site
56110000112	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
56110000113	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
56110000114	nucleotide binding site [chemical binding]; other site
56110000115	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
56110000116	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
56110000117	E3 interaction surface; other site
56110000118	lipoyl attachment site [posttranslational modification]; other site
56110000119	e3 binding domain; Region: E3_binding; pfam02817
56110000120	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
56110000121	Protein of unknown function (DUF2869); Region: DUF2869; pfam11068
56110000122	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
56110000123	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
56110000124	acyl-activating enzyme (AAE) consensus motif; other site
56110000125	putative AMP binding site [chemical binding]; other site
56110000126	putative active site [active]
56110000127	putative CoA binding site [chemical binding]; other site
56110000128	Retropepsins; pepsin-like aspartate proteases; Region: retropepsin_like; cd00303
56110000129	inhibitor binding site; inhibition site
56110000130	catalytic motif [active]
56110000131	Catalytic residue [active]
56110000132	Active site flap [active]
56110000133	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
56110000134	Leucine-rich repeats; other site
56110000135	Substrate binding site [chemical binding]; other site
56110000136	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110000137	Leucine rich repeat; Region: LRR_8; pfam13855
56110000138	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110000139	Leucine rich repeat; Region: LRR_8; pfam13855
56110000140	Leucine rich repeat; Region: LRR_8; pfam13855
56110000141	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
56110000142	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
56110000143	Walker A/P-loop; other site
56110000144	ATP binding site [chemical binding]; other site
56110000145	Q-loop/lid; other site
56110000146	ABC transporter signature motif; other site
56110000147	Walker B; other site
56110000148	D-loop; other site
56110000149	H-loop/switch region; other site
56110000150	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
56110000151	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110000152	dimer interface [polypeptide binding]; other site
56110000153	conserved gate region; other site
56110000154	putative PBP binding loops; other site
56110000155	ABC-ATPase subunit interface; other site
56110000156	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
56110000157	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
56110000158	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
56110000159	hydrogenase nickel insertion protein HypA; Region: hypA; TIGR00100
56110000160	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
56110000161	agmatinase; Region: agmatinase; TIGR01230
56110000162	Agmatinase-like family; Region: Agmatinase-like; cd09990
56110000163	active site
56110000164	oligomer interface [polypeptide binding]; other site
56110000165	Mn binding site [ion binding]; other site
56110000166	ykkC-yxkD leader; IMG reference gene:2509419254; Oscil6304_0047
56110000167	Alpha amylase catalytic domain found in maltogenic amylases, cyclodextrin glycosyltransferase, and related proteins; Region: AmyAc_AmyMalt_CGTase_like; cd11320
56110000168	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
56110000169	Ca binding site [ion binding]; other site
56110000170	active site
56110000171	catalytic site [active]
56110000172	The family 20 carbohydrate-binding module (CBM20), also known as the starch-binding domain, is found in a large number of starch degrading enzymes including alpha-amylase, beta-amylase, glucoamylase, and CGTase (cyclodextrin glucanotransferase). CBM20 is...; Region: CBM20; cd05467
56110000173	starch-binding site 2 [chemical binding]; other site
56110000174	starch-binding site 1 [chemical binding]; other site
56110000175	NusA N-terminal domain; Region: NusA_N; pfam08529
56110000176	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
56110000177	RNA binding site [nucleotide binding]; other site
56110000178	homodimer interface [polypeptide binding]; other site
56110000179	Transcription elongation factor [Transcription]; Region: NusA; COG0195
56110000180	NusA-like KH domain; Region: KH_5; pfam13184
56110000181	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
56110000182	G-X-X-G motif; other site
56110000183	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
56110000184	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110000185	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110000186	GH3 auxin-responsive promoter; Region: GH3; pfam03321
56110000187	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
56110000188	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
56110000189	putative trimer interface [polypeptide binding]; other site
56110000190	putative CoA binding site [chemical binding]; other site
56110000191	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
56110000192	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
56110000193	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
56110000194	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
56110000195	[2Fe-2S] cluster binding site [ion binding]; other site
56110000196	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
56110000197	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
56110000198	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110000199	catalytic loop [active]
56110000200	iron binding site [ion binding]; other site
56110000201	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
56110000202	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
56110000203	[2Fe-2S] cluster binding site [ion binding]; other site
56110000204	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
56110000205	dinuclear metal binding motif [ion binding]; other site
56110000206	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
56110000207	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
56110000208	iron-sulfur cluster [ion binding]; other site
56110000209	[2Fe-2S] cluster binding site [ion binding]; other site
56110000210	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110000211	structural tetrad; other site
56110000212	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110000213	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110000214	structural tetrad; other site
56110000215	Domain of unknown function (DUF4344); Region: DUF4344; pfam14247
56110000216	Protein of unknown function (DUF3318); Region: DUF3318; pfam11780
56110000217	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
56110000218	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110000219	FeS/SAM binding site; other site
56110000220	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
56110000221	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
56110000222	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
56110000223	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
56110000224	catalytic motif [active]
56110000225	Catalytic residue [active]
56110000226	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
56110000227	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
56110000228	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
56110000229	catalytic site [active]
56110000230	subunit interface [polypeptide binding]; other site
56110000231	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
56110000232	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110000233	anti sigma factor interaction site; other site
56110000234	regulatory phosphorylation site [posttranslational modification]; other site
56110000235	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
56110000236	active site
56110000237	metal binding site [ion binding]; metal-binding site
56110000238	dimerization interface [polypeptide binding]; other site
56110000239	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
56110000240	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
56110000241	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
56110000242	Domain of unknown function (DUF1816); Region: DUF1816; pfam08846
56110000243	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110000244	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
56110000245	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
56110000246	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
56110000247	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
56110000248	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
56110000249	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
56110000250	proline aminopeptidase P II; Provisional; Region: PRK10879
56110000251	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
56110000252	active site
56110000253	Domain of unknown function (DUF4332); Region: DUF4332; pfam14229
56110000254	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
56110000255	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
56110000256	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
56110000257	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
56110000258	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
56110000259	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
56110000260	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
56110000261	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
56110000262	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110000263	hypothetical protein; Provisional; Region: PRK09946
56110000264	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
56110000265	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
56110000266	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
56110000267	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
56110000268	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
56110000269	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110000270	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110000271	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110000272	ligand binding site [chemical binding]; other site
56110000273	flexible hinge region; other site
56110000274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
56110000275	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
56110000276	putative active site [active]
56110000277	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110000278	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
56110000279	Walker A/P-loop; other site
56110000280	ATP binding site [chemical binding]; other site
56110000281	Q-loop/lid; other site
56110000282	ABC transporter signature motif; other site
56110000283	Walker B; other site
56110000284	D-loop; other site
56110000285	H-loop/switch region; other site
56110000286	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
56110000287	PLD-like domain; Region: PLDc_2; pfam13091
56110000288	putative active site [active]
56110000289	catalytic site [active]
56110000290	AAA domain; Region: AAA_11; pfam13086
56110000291	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000292	Walker A motif; other site
56110000293	ATP binding site [chemical binding]; other site
56110000294	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
56110000295	AAA domain; Region: AAA_12; pfam13087
56110000296	Protein kinase domain; Region: Pkinase; pfam00069
56110000297	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110000298	active site
56110000299	ATP binding site [chemical binding]; other site
56110000300	substrate binding site [chemical binding]; other site
56110000301	activation loop (A-loop); other site
56110000302	TPR repeat; Region: TPR_11; pfam13414
56110000303	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000304	binding surface
56110000305	TPR motif; other site
56110000306	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110000307	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000308	binding surface
56110000309	TPR motif; other site
56110000310	Tetratricopeptide repeat; Region: TPR_1; pfam00515
56110000311	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000312	binding surface
56110000313	TPR motif; other site
56110000314	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000315	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
56110000316	Walker A motif; other site
56110000317	ATP binding site [chemical binding]; other site
56110000318	Walker B motif; other site
56110000319	arginine finger; other site
56110000320	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
56110000321	active site
56110000322	catalytic triad [active]
56110000323	Peptidase family M48; Region: Peptidase_M48; cl12018
56110000324	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
56110000325	catalytic residue [active]
56110000326	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
56110000327	NADH(P)-binding; Region: NAD_binding_10; pfam13460
56110000328	NAD(P) binding site [chemical binding]; other site
56110000329	putative active site [active]
56110000330	Protein of unknown function (DUF1997); Region: DUF1997; pfam09366
56110000331	Protein of unknown function (DUF4079); Region: DUF4079; pfam13301
56110000332	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
56110000333	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
56110000334	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
56110000335	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
56110000336	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
56110000337	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
56110000338	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
56110000339	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
56110000340	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
56110000341	Uncharacterized conserved protein (DUF2358); Region: DUF2358; pfam10184
56110000342	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
56110000343	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
56110000344	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
56110000345	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
56110000346	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
56110000347	active site
56110000348	Domain of Unknown Function (DUF1206); Region: DUF1206; pfam06724
56110000349	Domain of Unknown Function (DUF1206); Region: DUF1206; pfam06724
56110000350	Domain of Unknown Function (DUF1206); Region: DUF1206; pfam06724
56110000351	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
56110000352	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110000353	putative substrate translocation pore; other site
56110000354	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110000355	putative active site [active]
56110000356	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
56110000357	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000358	binding surface
56110000359	TPR motif; other site
56110000360	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110000361	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000362	binding surface
56110000363	TPR motif; other site
56110000364	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000365	binding surface
56110000366	TPR motif; other site
56110000367	CHAT domain; Region: CHAT; pfam12770
56110000368	Prolyl 4-hydroxylase alpha subunit homologues; Region: P4Hc; smart00702
56110000369	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
56110000370	Cupin-like domain; Region: Cupin_8; pfam13621
56110000371	Cupin-like domain; Region: Cupin_8; pfam13621
56110000372	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
56110000373	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
56110000374	purine monophosphate binding site [chemical binding]; other site
56110000375	dimer interface [polypeptide binding]; other site
56110000376	putative catalytic residues [active]
56110000377	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
56110000378	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
56110000379	GrpE; Region: GrpE; pfam01025
56110000380	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
56110000381	dimer interface [polypeptide binding]; other site
56110000382	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
56110000383	molecular chaperone DnaK; Provisional; Region: PRK13411
56110000384	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
56110000385	nucleotide binding site [chemical binding]; other site
56110000386	NEF interaction site [polypeptide binding]; other site
56110000387	SBD interface [polypeptide binding]; other site
56110000388	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
56110000389	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110000390	HSP70 interaction site [polypeptide binding]; other site
56110000391	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
56110000392	Zn binding sites [ion binding]; other site
56110000393	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
56110000394	dimer interface [polypeptide binding]; other site
56110000395	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
56110000396	CPxP  motif; other site
56110000397	GTPase RsgA; Reviewed; Region: PRK12289
56110000398	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
56110000399	RNA binding site [nucleotide binding]; other site
56110000400	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
56110000401	GTPase/Zn-binding domain interface [polypeptide binding]; other site
56110000402	GTP/Mg2+ binding site [chemical binding]; other site
56110000403	G4 box; other site
56110000404	G5 box; other site
56110000405	G1 box; other site
56110000406	Switch I region; other site
56110000407	G2 box; other site
56110000408	G3 box; other site
56110000409	Switch II region; other site
56110000410	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
56110000411	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
56110000412	oligomeric interface; other site
56110000413	putative active site [active]
56110000414	homodimer interface [polypeptide binding]; other site
56110000415	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
56110000416	NACHT domain; Region: NACHT; pfam05729
56110000417	HEAT repeats; Region: HEAT_2; pfam13646
56110000418	HEAT repeats; Region: HEAT_2; pfam13646
56110000419	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
56110000420	protein binding surface [polypeptide binding]; other site
56110000421	HEAT repeats; Region: HEAT_2; pfam13646
56110000422	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
56110000423	protein binding surface [polypeptide binding]; other site
56110000424	HEAT-like repeat; Region: HEAT_EZ; pfam13513
56110000425	Uncharacterized small protein [Function unknown]; Region: COG2886
56110000426	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
56110000427	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
56110000428	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
56110000429	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110000430	putative active site [active]
56110000431	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110000432	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110000433	active site
56110000434	ATP binding site [chemical binding]; other site
56110000435	substrate binding site [chemical binding]; other site
56110000436	activation loop (A-loop); other site
56110000437	CpcD/allophycocyanin linker domain; Region: CpcD; pfam01383
56110000438	ferredoxin--NADP(+) reductase; Provisional; Region: PLN03115
56110000439	These ferredoxin reductases are related to the NADPH cytochrome p450 reductases (CYPOR), but lack the FAD-binding region connecting sub-domain. Ferredoxin-NADP+ reductase (FNR) is an FAD-containing enzyme that catalyzes the reversible electron transfer...; Region: CYPOR_like_FNR; cd06208
56110000440	dimerization interface [polypeptide binding]; other site
56110000441	FAD binding pocket [chemical binding]; other site
56110000442	FAD binding motif [chemical binding]; other site
56110000443	catalytic residues [active]
56110000444	NAD binding pocket [chemical binding]; other site
56110000445	phosphate binding motif [ion binding]; other site
56110000446	beta-alpha-beta structure motif; other site
56110000447	phosphoribulokinase; Provisional; Region: PRK07429
56110000448	Phosphoribulokinase (PRK) is an enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. This enzyme catalyzes the phosphorylation of D-ribulose 5-phosphate to form D-ribulose 1, 5-biphosphate, using ATP and NADPH...; Region: PRK; cd02026
56110000449	active site
56110000450	Thiopurine S-methyltransferase (TPMT); Region: TPMT; pfam05724
56110000451	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110000452	S-adenosylmethionine binding site [chemical binding]; other site
56110000453	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
56110000454	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000455	Walker A motif; other site
56110000456	ATP binding site [chemical binding]; other site
56110000457	Walker B motif; other site
56110000458	arginine finger; other site
56110000459	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000460	Walker A motif; other site
56110000461	ATP binding site [chemical binding]; other site
56110000462	Walker B motif; other site
56110000463	arginine finger; other site
56110000464	Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: ArsA; COG0003
56110000465	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
56110000466	P loop; other site
56110000467	Nucleotide binding site [chemical binding]; other site
56110000468	DTAP/Switch II; other site
56110000469	Switch I; other site
56110000470	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
56110000471	Anion-transporting ATPase; Region: ArsA_ATPase; pfam02374
56110000472	DTAP/Switch II; other site
56110000473	Switch I; other site
56110000474	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
56110000475	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
56110000476	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
56110000477	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
56110000478	gas vesicle protein GvpN; Region: gas_vesic_GvpN; TIGR02640
56110000479	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000480	Walker A motif; other site
56110000481	ATP binding site [chemical binding]; other site
56110000482	Walker B motif; other site
56110000483	arginine finger; other site
56110000484	gas vesicle synthesis protein GvpA; Provisional; Region: PRK09371
56110000485	Gas vesicle protein; Region: Gas_vesicle; pfam00741
56110000486	Gas vesicle protein K; Region: GvpK; pfam05121
56110000487	Gas vesicle protein; Region: Gas_vesicle; pfam00741
56110000488	Gas vesicle synthesis protein GvpL/GvpF; Region: GvpL_GvpF; pfam06386
56110000489	Gas vesicle protein G; Region: GvpG; pfam05120
56110000490	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
56110000491	Uncharacterized conserved protein [Function unknown]; Region: COG0432
56110000492	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
56110000493	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
56110000494	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110000495	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110000496	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110000497	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
56110000498	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
56110000499	HIGH motif; other site
56110000500	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
56110000501	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
56110000502	active site
56110000503	KMSKS motif; other site
56110000504	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
56110000505	tRNA binding surface [nucleotide binding]; other site
56110000506	anticodon binding site; other site
56110000507	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
56110000508	TIGR03790 family protein; Region: TIGR03790
56110000509	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
56110000510	NADPH bind site [chemical binding]; other site
56110000511	putative FMN binding site [chemical binding]; other site
56110000512	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
56110000513	putative FMN binding site [chemical binding]; other site
56110000514	NADPH bind site [chemical binding]; other site
56110000515	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
56110000516	Domain of unknown function (DUF3368); Region: DUF3368; pfam11848
56110000517	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110000518	Large family of predicted nucleotide-binding domains; Region: PINc; smart00670
56110000519	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
56110000520	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110000521	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110000522	active site
56110000523	NTP binding site [chemical binding]; other site
56110000524	metal binding triad [ion binding]; metal-binding site
56110000525	antibiotic binding site [chemical binding]; other site
56110000526	Uncharacterized conserved protein [Function unknown]; Region: COG2361
56110000527	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2402
56110000528	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000529	binding surface
56110000530	TPR motif; other site
56110000531	TPR repeat; Region: TPR_11; pfam13414
56110000532	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110000533	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110000534	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110000535	Tetratricopeptide repeat; Region: TPR_10; pfam13374
56110000536	CHAT domain; Region: CHAT; pfam12770
56110000537	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
56110000538	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110000539	catalytic residue [active]
56110000540	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
56110000541	MASE1; Region: MASE1; cl17823
56110000542	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110000543	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110000544	dimer interface [polypeptide binding]; other site
56110000545	phosphorylation site [posttranslational modification]
56110000546	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110000547	ATP binding site [chemical binding]; other site
56110000548	Mg2+ binding site [ion binding]; other site
56110000549	G-X-G motif; other site
56110000550	Response regulator receiver domain; Region: Response_reg; pfam00072
56110000551	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110000552	active site
56110000553	phosphorylation site [posttranslational modification]
56110000554	intermolecular recognition site; other site
56110000555	dimerization interface [polypeptide binding]; other site
56110000556	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110000557	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110000558	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
56110000559	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
56110000560	trmE is a tRNA modification GTPase; Region: trmE; cd04164
56110000561	G1 box; other site
56110000562	GTP/Mg2+ binding site [chemical binding]; other site
56110000563	Switch I region; other site
56110000564	G2 box; other site
56110000565	Switch II region; other site
56110000566	G3 box; other site
56110000567	G4 box; other site
56110000568	G5 box; other site
56110000569	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
56110000570	Uncharacterized protein conserved in bacteria (DUF2062); Region: DUF2062; pfam09835
56110000571	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110000572	putative active site [active]
56110000573	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110000574	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110000575	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110000576	structural tetrad; other site
56110000577	S-layer homology domain; Region: SLH; pfam00395
56110000578	S-layer homology domain; Region: SLH; pfam00395
56110000579	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110000580	structural tetrad; other site
56110000581	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110000582	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110000583	S-adenosylmethionine binding site [chemical binding]; other site
56110000584	homoserine dehydrogenase; Provisional; Region: PRK06349
56110000585	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
56110000586	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
56110000587	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
56110000588	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
56110000589	putative active site [active]
56110000590	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
56110000591	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110000592	putative active site [active]
56110000593	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
56110000594	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
56110000595	trimer interface [polypeptide binding]; other site
56110000596	active site
56110000597	substrate binding site [chemical binding]; other site
56110000598	CoA binding site [chemical binding]; other site
56110000599	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
56110000600	Uncharacterized conserved protein [Function unknown]; Region: COG3379
56110000601	Uncharacterized conserved protein [Function unknown]; Region: COG3379
56110000602	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110000603	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110000604	active site
56110000605	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110000606	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110000607	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110000608	active site
56110000609	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110000610	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110000611	coproporphyrinogen III oxidase; Provisional; Region: PRK07379
56110000612	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110000613	FeS/SAM binding site; other site
56110000614	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
56110000615	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
56110000616	putative active site [active]
56110000617	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
56110000618	nucleoside/Zn binding site; other site
56110000619	dimer interface [polypeptide binding]; other site
56110000620	catalytic motif [active]
56110000621	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
56110000622	photochlorophyllide reductase subunit L; Region: chlL; CHL00072
56110000623	This family of proteins contains bchL and chlL. Protochlorophyllide reductase catalyzes the reductive formation of chlorophyllide from protochlorophyllide during biosynthesis of chlorophylls and bacteriochlorophylls. Three genes, bchL, bchN and bchB, are...; Region: Bchl_like; cd02032
56110000624	P-loop; other site
56110000625	Pchlide_reductase_N: N protein of the NB protein complex of Protochlorophyllide (Pchlide)_reductase. Pchlide reductase catalyzes the reductive formation of chlorophyllide (chlide) from protochlorophyllide (pchlide) during biosynthesis of chlorophylls and...; Region: Pchlide_reductase_N; cd01979
56110000626	light-independent protochlorophyllide reductase, N subunit; Region: DPOR_bchN; TIGR01279
56110000627	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110000628	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110000629	active site
56110000630	ATP binding site [chemical binding]; other site
56110000631	substrate binding site [chemical binding]; other site
56110000632	activation loop (A-loop); other site
56110000633	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
56110000634	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110000635	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110000636	active site
56110000637	ATP binding site [chemical binding]; other site
56110000638	substrate binding site [chemical binding]; other site
56110000639	activation loop (A-loop); other site
56110000640	Protein of unknown function (DUF4101); Region: DUF4101; pfam13355
56110000641	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110000642	phosphopeptide binding site; other site
56110000643	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110000644	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110000645	phosphopeptide binding site; other site
56110000646	Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; Region: ABCG_EPDR; cd03213
56110000647	The Eye Pigment Precursor Transporter (EPP) Family protein; Region: 3a01204; TIGR00955
56110000648	Walker A/P-loop; other site
56110000649	ATP binding site [chemical binding]; other site
56110000650	Q-loop/lid; other site
56110000651	ABC transporter signature motif; other site
56110000652	Walker B; other site
56110000653	D-loop; other site
56110000654	H-loop/switch region; other site
56110000655	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
56110000656	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
56110000657	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110000658	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110000659	active site
56110000660	ATP binding site [chemical binding]; other site
56110000661	substrate binding site [chemical binding]; other site
56110000662	activation loop (A-loop); other site
56110000663	GIY-YIG domain found in CAXIP1-like proteins, iron-sulfur cluster assembly proteins, and similar proteins; Region: GIY-YIG_AtGrxS16_like; cd10450
56110000664	GIY-YIG motif/motif A; other site
56110000665	TPR repeat; Region: TPR_11; pfam13414
56110000666	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
56110000667	Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_9; cd06344
56110000668	putative ligand binding site [chemical binding]; other site
56110000669	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
56110000670	metal ion-dependent adhesion site (MIDAS); other site
56110000671	Putative addiction module component; Region: Unstab_antitox; pfam09720
56110000672	acetohydroxyacid synthase small subunit; Region: ilvH; CHL00100
56110000673	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
56110000674	putative valine binding site [chemical binding]; other site
56110000675	dimer interface [polypeptide binding]; other site
56110000676	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
56110000677	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
56110000678	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
56110000679	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
56110000680	nitrilase; Region: PLN02798
56110000681	putative active site [active]
56110000682	catalytic triad [active]
56110000683	dimer interface [polypeptide binding]; other site
56110000684	Tic22-like family; Region: Tic22; pfam04278
56110000685	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
56110000686	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110000687	S-adenosylmethionine binding site [chemical binding]; other site
56110000688	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
56110000689	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110000690	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110000691	dimer interface [polypeptide binding]; other site
56110000692	phosphorylation site [posttranslational modification]
56110000693	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
56110000694	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110000695	Coenzyme A binding pocket [chemical binding]; other site
56110000696	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
56110000697	dimer interface [polypeptide binding]; other site
56110000698	active site
56110000699	Schiff base residues; other site
56110000700	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
56110000701	ribosomal protein L21; Region: rpl21; CHL00075
56110000702	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
56110000703	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
56110000704	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
56110000705	chloroplast protein import component, Tic20 family; Region: 3a0901s05TIC20; TIGR00994
56110000706	Peptidase_C39 like family; Region: Peptidase_C39_2; pfam13529
56110000707	putative active site [active]
56110000708	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
56110000709	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110000710	catalytic triad [active]
56110000711	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
56110000712	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110000713	catalytic triad [active]
56110000714	cobyric acid synthase; Provisional; Region: PRK00784
56110000715	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
56110000716	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
56110000717	catalytic triad [active]
56110000718	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110000719	catalytic loop [active]
56110000720	iron binding site [ion binding]; other site
56110000721	FOG: CBS domain [General function prediction only]; Region: COG0517
56110000722	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110000723	FOG: CBS domain [General function prediction only]; Region: COG0517
56110000724	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with a PAS domain, a GGDEF (DiGuanylate-Cyclase (DGC) domain, and a DUF1 domain downstream. PAS domains have been found to bind ligands, and to act...; Region: CBS_pair_PAS_GGDEF_DUF1_assoc; cd04611
56110000725	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110000726	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110000727	dimer interface [polypeptide binding]; other site
56110000728	phosphorylation site [posttranslational modification]
56110000729	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110000730	ATP binding site [chemical binding]; other site
56110000731	Mg2+ binding site [ion binding]; other site
56110000732	G-X-G motif; other site
56110000733	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_8; cd07817
56110000734	putative hydrophobic ligand binding site [chemical binding]; other site
56110000735	9,9'-di-cis-zeta-carotene desaturase; Region: zeta_caro_desat; TIGR02732
56110000736	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110000737	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
56110000738	ACT_MalLac-Enz CD includes the N-terminal ACT domain of putative NAD-dependent malic enzyme 1, Bacillus subtilis YqkI and related domains; Region: ACT_MalLac-Enz; cd04887
56110000739	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
56110000740	Malic enzyme, N-terminal domain; Region: malic; pfam00390
56110000741	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
56110000742	putative NAD(P) binding site [chemical binding]; other site
56110000743	MASE1; Region: MASE1; pfam05231
56110000744	PAS domain S-box; Region: sensory_box; TIGR00229
56110000745	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110000746	putative active site [active]
56110000747	heme pocket [chemical binding]; other site
56110000748	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110000749	PAS domain; Region: PAS_9; pfam13426
56110000750	putative active site [active]
56110000751	heme pocket [chemical binding]; other site
56110000752	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110000753	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110000754	phosphorylation site [posttranslational modification]
56110000755	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110000756	ATP binding site [chemical binding]; other site
56110000757	Mg2+ binding site [ion binding]; other site
56110000758	G-X-G motif; other site
56110000759	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
56110000760	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
56110000761	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
56110000762	Uncharacterized conserved protein [Function unknown]; Region: COG1432
56110000763	LabA_like proteins; Region: LabA; cd10911
56110000764	putative metal binding site [ion binding]; other site
56110000765	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
56110000766	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
56110000767	active site
56110000768	HIGH motif; other site
56110000769	KMSKS motif; other site
56110000770	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
56110000771	anticodon binding site; other site
56110000772	tRNA binding surface [nucleotide binding]; other site
56110000773	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
56110000774	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
56110000775	putative acyl-acceptor binding pocket; other site
56110000776	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110000777	Protein of unknown function (DUF3370); Region: DUF3370; pfam11850
56110000778	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110000779	active site
56110000780	NTP binding site [chemical binding]; other site
56110000781	metal binding triad [ion binding]; metal-binding site
56110000782	antibiotic binding site [chemical binding]; other site
56110000783	Protein of unknown function DUF86; Region: DUF86; cl01031
56110000784	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
56110000785	Mg binding site [ion binding]; other site
56110000786	nucleotide binding site [chemical binding]; other site
56110000787	putative protofilament interface [polypeptide binding]; other site
56110000788	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
56110000789	homotrimer interaction site [polypeptide binding]; other site
56110000790	putative active site [active]
56110000791	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110000792	PAS domain; Region: PAS_9; pfam13426
56110000793	putative active site [active]
56110000794	heme pocket [chemical binding]; other site
56110000795	PAS domain; Region: PAS_9; pfam13426
56110000796	PAS fold; Region: PAS_4; pfam08448
56110000797	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110000798	putative active site [active]
56110000799	heme pocket [chemical binding]; other site
56110000800	PAS fold; Region: PAS_4; pfam08448
56110000801	PAS fold; Region: PAS_3; pfam08447
56110000802	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
56110000803	PAS domain S-box; Region: sensory_box; TIGR00229
56110000804	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110000805	putative active site [active]
56110000806	heme pocket [chemical binding]; other site
56110000807	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110000808	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110000809	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110000810	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110000811	metal binding site [ion binding]; metal-binding site
56110000812	active site
56110000813	I-site; other site
56110000814	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
56110000815	nudix motif; other site
56110000816	4-alpha-glucanotransferase; Provisional; Region: PRK14508
56110000817	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110000818	non-specific DNA binding site [nucleotide binding]; other site
56110000819	salt bridge; other site
56110000820	sequence-specific DNA binding site [nucleotide binding]; other site
56110000821	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
56110000822	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
56110000823	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
56110000824	RNA binding surface [nucleotide binding]; other site
56110000825	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
56110000826	active site
56110000827	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
56110000828	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
56110000829	phosphatidate cytidylyltransferase; Region: PLN02953
56110000830	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
56110000831	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110000832	S-adenosylmethionine binding site [chemical binding]; other site
56110000833	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
56110000834	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
56110000835	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110000836	catalytic residue [active]
56110000837	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
56110000838	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000839	binding surface
56110000840	TPR motif; other site
56110000841	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110000842	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
56110000843	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4246
56110000844	TPR repeat; Region: TPR_11; pfam13414
56110000845	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000846	binding surface
56110000847	TPR motif; other site
56110000848	TPR repeat; Region: TPR_11; pfam13414
56110000849	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000850	binding surface
56110000851	TPR motif; other site
56110000852	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000853	TPR motif; other site
56110000854	TPR repeat; Region: TPR_11; pfam13414
56110000855	binding surface
56110000856	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110000857	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110000858	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110000859	Protein of unknown function (DUF4101); Region: DUF4101; pfam13355
56110000860	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
56110000861	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
56110000862	Walker A/P-loop; other site
56110000863	ATP binding site [chemical binding]; other site
56110000864	Q-loop/lid; other site
56110000865	ABC transporter signature motif; other site
56110000866	Walker B; other site
56110000867	D-loop; other site
56110000868	H-loop/switch region; other site
56110000869	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
56110000870	Fasciclin domain; Region: Fasciclin; pfam02469
56110000871	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
56110000872	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
56110000873	active site
56110000874	homodimer interface [polypeptide binding]; other site
56110000875	catalytic site [active]
56110000876	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
56110000877	PetM family of cytochrome b6f complex subunit 7; Region: PetM; pfam08041
56110000878	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
56110000879	Domain of unknown function DUF20; Region: UPF0118; pfam01594
56110000880	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
56110000881	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
56110000882	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
56110000883	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110000884	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110000885	S-adenosylmethionine binding site [chemical binding]; other site
56110000886	Type IV pilin PilA; Region: Pilin_PilA; pfam14245
56110000887	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000888	binding surface
56110000889	TPR motif; other site
56110000890	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
56110000891	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000892	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110000893	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
56110000894	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
56110000895	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
56110000896	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
56110000897	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000898	TPR motif; other site
56110000899	binding surface
56110000900	TPR repeat; Region: TPR_11; pfam13414
56110000901	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110000902	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110000903	Methyltransferase domain; Region: Methyltransf_24; pfam13578
56110000904	Polysaccharide biosynthesis; Region: Polysacc_synt_4; cl04661
56110000905	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110000906	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110000907	TPR motif; other site
56110000908	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110000909	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
56110000910	putative metal binding site; other site
56110000911	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110000912	binding surface
56110000913	TPR motif; other site
56110000914	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
56110000915	homodimer interface [polypeptide binding]; other site
56110000916	substrate-cofactor binding pocket; other site
56110000917	Aminotransferase class IV; Region: Aminotran_4; pfam01063
56110000918	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110000919	catalytic residue [active]
56110000920	FtsH Extracellular; Region: FtsH_ext; pfam06480
56110000921	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
56110000922	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000923	Walker A motif; other site
56110000924	ATP binding site [chemical binding]; other site
56110000925	Walker B motif; other site
56110000926	arginine finger; other site
56110000927	Peptidase family M41; Region: Peptidase_M41; pfam01434
56110000928	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110000929	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110000930	active site
56110000931	ATP binding site [chemical binding]; other site
56110000932	substrate binding site [chemical binding]; other site
56110000933	activation loop (A-loop); other site
56110000934	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110000935	structural tetrad; other site
56110000936	PQQ-like domain; Region: PQQ_2; pfam13360
56110000937	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
56110000938	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
56110000939	active site
56110000940	intersubunit interface [polypeptide binding]; other site
56110000941	catalytic residue [active]
56110000942	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
56110000943	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
56110000944	Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170
56110000945	MreB/Mbl protein; Region: MreB_Mbl; pfam06723
56110000946	nucleotide binding site [chemical binding]; other site
56110000947	putative NEF/HSP70 interaction site [polypeptide binding]; other site
56110000948	SBD interface [polypeptide binding]; other site
56110000949	CHASE3 domain; Region: CHASE3; cl05000
56110000950	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
56110000951	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110000952	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110000953	dimer interface [polypeptide binding]; other site
56110000954	putative CheW interface [polypeptide binding]; other site
56110000955	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
56110000956	nucleotide binding site/active site [active]
56110000957	HIT family signature motif; other site
56110000958	catalytic residue [active]
56110000959	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG1848
56110000960	putative active site [active]
56110000961	Mg chelatase-related protein; Region: TIGR00368
56110000962	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
56110000963	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110000964	Walker A motif; other site
56110000965	ATP binding site [chemical binding]; other site
56110000966	Walker B motif; other site
56110000967	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
56110000968	adenylosuccinate lyase; Provisional; Region: PRK07380
56110000969	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
56110000970	tetramer interface [polypeptide binding]; other site
56110000971	active site
56110000972	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
56110000973	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
56110000974	PQQ-like domain; Region: PQQ_2; pfam13360
56110000975	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110000976	structural tetrad; other site
56110000977	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
56110000978	Bacterial SH3 domain; Region: SH3_3; pfam08239
56110000979	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110000980	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110000981	ligand binding site [chemical binding]; other site
56110000982	flexible hinge region; other site
56110000983	TLC ATP/ADP transporter; Region: TLC; cl03940
56110000984	HEAT repeats; Region: HEAT_2; pfam13646
56110000985	HEAT repeats; Region: HEAT_2; pfam13646
56110000986	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
56110000987	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
56110000988	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
56110000989	Protein of unknown function (DUF3747); Region: DUF3747; pfam12565
56110000990	S-layer homology domain; Region: SLH; pfam00395
56110000991	S-layer homology domain; Region: SLH; pfam00395
56110000992	Spc7 kinetochore protein; Region: Spc7; pfam08317
56110000993	AAA domain; Region: AAA_21; pfam13304
56110000994	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110000995	Walker B; other site
56110000996	D-loop; other site
56110000997	H-loop/switch region; other site
56110000998	Predicted bile acid beta-glucosidase [Carbohydrate transport and metabolism]; Region: COG4354
56110000999	beta-Glucocerebrosidase 2 N terminal; Region: GBA2_N; pfam12215
56110001000	Protein of unknown function, DUF608; Region: DUF608; pfam04685
56110001001	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110001002	Beta-propeller repeat; Region: SBBP; pfam06739
56110001003	Beta-propeller repeat; Region: SBBP; pfam06739
56110001004	Beta-propeller repeat; Region: SBBP; pfam06739
56110001005	Beta-propeller repeat; Region: SBBP; pfam06739
56110001006	Beta-propeller repeat; Region: SBBP; pfam06739
56110001007	Beta-propeller repeat; Region: SBBP; pfam06739
56110001008	Beta-propeller repeat; Region: SBBP; pfam06739
56110001009	Calx-beta domain; Region: Calx-beta; cl02522
56110001010	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
56110001011	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
56110001012	Bacterial Ig-like domain; Region: Big_5; pfam13205
56110001013	Bacterial Ig-like domain; Region: Big_5; pfam13205
56110001014	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110001015	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
56110001016	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
56110001017	Walker A/P-loop; other site
56110001018	ATP binding site [chemical binding]; other site
56110001019	Q-loop/lid; other site
56110001020	ABC transporter signature motif; other site
56110001021	Walker B; other site
56110001022	D-loop; other site
56110001023	H-loop/switch region; other site
56110001024	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
56110001025	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110001026	dimer interface [polypeptide binding]; other site
56110001027	conserved gate region; other site
56110001028	putative PBP binding loops; other site
56110001029	ABC-ATPase subunit interface; other site
56110001030	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
56110001031	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110001032	dimer interface [polypeptide binding]; other site
56110001033	putative PBP binding loops; other site
56110001034	ABC-ATPase subunit interface; other site
56110001035	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
56110001036	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
56110001037	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110001038	Protein of unknown function (DUF1622); Region: DUF1622; pfam07784
56110001039	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110001040	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110001041	active site
56110001042	ATP binding site [chemical binding]; other site
56110001043	substrate binding site [chemical binding]; other site
56110001044	activation loop (A-loop); other site
56110001045	Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]; Region: RpsA; COG0539
56110001046	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
56110001047	RNA binding site [nucleotide binding]; other site
56110001048	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
56110001049	RNA binding site [nucleotide binding]; other site
56110001050	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
56110001051	Protein phosphatase 2C; Region: PP2C; pfam00481
56110001052	active site
56110001053	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
56110001054	metal ion-dependent adhesion site (MIDAS); other site
56110001055	Protein of unknown function (DUF433); Region: DUF433; cl01030
56110001056	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
56110001057	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110001058	non-specific DNA binding site [nucleotide binding]; other site
56110001059	salt bridge; other site
56110001060	sequence-specific DNA binding site [nucleotide binding]; other site
56110001061	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110001062	non-specific DNA binding site [nucleotide binding]; other site
56110001063	salt bridge; other site
56110001064	sequence-specific DNA binding site [nucleotide binding]; other site
56110001065	Uncharacterized protein family (UPF0175); Region: UPF0175; cl01085
56110001066	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
56110001067	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
56110001068	substrate-cofactor binding pocket; other site
56110001069	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110001070	catalytic residue [active]
56110001071	TPR repeat; Region: TPR_11; pfam13414
56110001072	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001073	binding surface
56110001074	TPR motif; other site
56110001075	TPR repeat; Region: TPR_11; pfam13414
56110001076	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001077	binding surface
56110001078	TPR motif; other site
56110001079	TPR repeat; Region: TPR_11; pfam13414
56110001080	TPR repeat; Region: TPR_11; pfam13414
56110001081	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001082	binding surface
56110001083	TPR motif; other site
56110001084	TPR repeat; Region: TPR_11; pfam13414
56110001085	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
56110001086	S-layer homology domain; Region: SLH; pfam00395
56110001087	Uncharacterized conserved protein [Function unknown]; Region: COG1434
56110001088	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
56110001089	putative active site [active]
56110001090	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
56110001091	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
56110001092	M42 glutamyl aminopeptidase; Region: Peptidase_M42; pfam05343
56110001093	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
56110001094	ABC1 family; Region: ABC1; cl17513
56110001095	GAF domain; Region: GAF; pfam01590
56110001096	GAF domain; Region: GAF; pfam01590
56110001097	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110001098	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110001099	dimer interface [polypeptide binding]; other site
56110001100	phosphorylation site [posttranslational modification]
56110001101	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110001102	ATP binding site [chemical binding]; other site
56110001103	Mg2+ binding site [ion binding]; other site
56110001104	G-X-G motif; other site
56110001105	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
56110001106	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
56110001107	active site
56110001108	metal binding site [ion binding]; metal-binding site
56110001109	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
56110001110	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110001111	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001112	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001113	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001114	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001115	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001116	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001117	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001118	HNH endonuclease; Region: HNH_2; pfam13391
56110001119	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
56110001120	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110001121	S-adenosylmethionine binding site [chemical binding]; other site
56110001122	EamA-like transporter family; Region: EamA; pfam00892
56110001123	EamA-like transporter family; Region: EamA; pfam00892
56110001124	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110001125	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001126	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001127	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110001128	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001129	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001130	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110001131	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001132	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001133	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001134	Surface antigen; Region: Bac_surface_Ag; pfam01103
56110001135	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001136	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110001137	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001138	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001139	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
56110001140	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
56110001141	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
56110001142	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
56110001143	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110001144	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110001145	acyl-activating enzyme (AAE) consensus motif; other site
56110001146	AMP binding site [chemical binding]; other site
56110001147	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110001148	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
56110001149	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
56110001150	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
56110001151	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110001152	Magnesium ion binding site [ion binding]; other site
56110001153	Condensation domain; Region: Condensation; pfam00668
56110001154	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110001155	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110001156	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110001157	acyl-activating enzyme (AAE) consensus motif; other site
56110001158	AMP binding site [chemical binding]; other site
56110001159	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110001160	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110001161	S-adenosylmethionine binding site [chemical binding]; other site
56110001162	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
56110001163	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110001164	Condensation domain; Region: Condensation; pfam00668
56110001165	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110001166	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110001167	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
56110001168	acyl-activating enzyme (AAE) consensus motif; other site
56110001169	AMP binding site [chemical binding]; other site
56110001170	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110001171	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
56110001172	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
56110001173	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110001174	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
56110001175	oligomeric interface; other site
56110001176	putative active site [active]
56110001177	homodimer interface [polypeptide binding]; other site
56110001178	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110001179	CRISPR-associated (Cas) DxTHG family; Region: Cas_DxTHG; pfam09455
56110001180	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cd09732
56110001181	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cl17439
56110001182	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214
56110001183	Protein of unknown function, DUF601; Region: DUF601; pfam04642
56110001184	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214
56110001185	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214
56110001186	CRISPR/Cas system-associated protein Csm6; Region: Csm6_III-A; cd09742
56110001187	CRISPR/Cas system-associated RAMP superfamily protein Csx10; Region: Csx10; cl17558
56110001188	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214
56110001189	CRISPR-associated protein Cas10/Cmr2, subtype III-B; Region: cas_TM1794_Cmr2; TIGR02577
56110001190	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853
56110001191	CRISPR/Cas system-associated protein Csx3; Region: Csx3_III-U; cd09740
56110001192	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
56110001193	Walker A motif; other site
56110001194	ATP binding site [chemical binding]; other site
56110001195	CRISPR-associated protein, TIGR03985 family; Region: TIGR03985
56110001196	Head domain of virus receptor-binding proteins (RBP); Region: RBP-H; cl07506
56110001197	trimer interface [polypeptide binding]; other site
56110001198	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
56110001199	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
56110001200	catalytic residues [active]
56110001201	catalytic nucleophile [active]
56110001202	Presynaptic Site I dimer interface [polypeptide binding]; other site
56110001203	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
56110001204	Synaptic Flat tetramer interface [polypeptide binding]; other site
56110001205	Synaptic Site I dimer interface [polypeptide binding]; other site
56110001206	DNA binding site [nucleotide binding]
56110001207	Recombinase; Region: Recombinase; pfam07508
56110001208	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110001209	non-specific DNA binding site [nucleotide binding]; other site
56110001210	salt bridge; other site
56110001211	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
56110001212	sequence-specific DNA binding site [nucleotide binding]; other site
56110001213	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
56110001214	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110001215	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
56110001216	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
56110001217	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001218	binding surface
56110001219	TPR motif; other site
56110001220	TPR repeat; Region: TPR_11; pfam13414
56110001221	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
56110001222	PAP_fibrillin; Region: PAP_fibrillin; pfam04755
56110001223	Protein of unknown function (DUF3134); Region: DUF3134; pfam11332
56110001224	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
56110001225	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
56110001226	Mg++ binding site [ion binding]; other site
56110001227	putative catalytic motif [active]
56110001228	putative substrate binding site [chemical binding]; other site
56110001229	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110001230	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110001231	active site
56110001232	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
56110001233	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110001234	motif II; other site
56110001235	Domain of unknown function (DUF1830); Region: DUF1830; pfam08865
56110001236	SprT homologues; Region: SprT; cl01182
56110001237	HIRAN domain; Region: HIRAN; pfam08797
56110001238	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
56110001239	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110001240	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110001241	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110001242	CHASE2 domain; Region: CHASE2; pfam05226
56110001243	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110001244	cyclase homology domain; Region: CHD; cd07302
56110001245	nucleotidyl binding site; other site
56110001246	metal binding site [ion binding]; metal-binding site
56110001247	dimer interface [polypeptide binding]; other site
56110001248	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
56110001249	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
56110001250	generic binding surface II; other site
56110001251	generic binding surface I; other site
56110001252	recombinase A; Provisional; Region: recA; PRK09354
56110001253	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
56110001254	hexamer interface [polypeptide binding]; other site
56110001255	Walker A motif; other site
56110001256	ATP binding site [chemical binding]; other site
56110001257	Walker B motif; other site
56110001258	HEAT repeats; Region: HEAT_2; pfam13646
56110001259	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747
56110001260	HEAT repeats; Region: HEAT_2; pfam13646
56110001261	GTPase RsgA; Reviewed; Region: PRK01889
56110001262	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
56110001263	RNA binding site [nucleotide binding]; other site
56110001264	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
56110001265	GTPase/Zn-binding domain interface [polypeptide binding]; other site
56110001266	GTP/Mg2+ binding site [chemical binding]; other site
56110001267	G4 box; other site
56110001268	G5 box; other site
56110001269	G1 box; other site
56110001270	Switch I region; other site
56110001271	G2 box; other site
56110001272	G3 box; other site
56110001273	Switch II region; other site
56110001274	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110001275	NADH(P)-binding; Region: NAD_binding_10; pfam13460
56110001276	NAD(P) binding site [chemical binding]; other site
56110001277	Complex I intermediate-associated protein 30 (CIA30); Region: CIA30; pfam08547
56110001278	NADH(P)-binding; Region: NAD_binding_10; pfam13460
56110001279	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110001280	active site
56110001281	Protein of unknown function, DUF481; Region: DUF481; pfam04338
56110001282	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK07364
56110001283	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
56110001284	S-layer homology domain; Region: SLH; pfam00395
56110001285	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110001286	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110001287	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
56110001288	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110001289	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
56110001290	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
56110001291	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
56110001292	putative active site [active]
56110001293	adenylation catalytic residue [active]
56110001294	Protein of unknown function (DUF1092); Region: DUF1092; pfam06485
56110001295	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
56110001296	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
56110001297	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
56110001298	Cl- selectivity filter; other site
56110001299	Cl- binding residues [ion binding]; other site
56110001300	pore gating glutamate residue; other site
56110001301	dimer interface [polypeptide binding]; other site
56110001302	H+/Cl- coupling transport residue; other site
56110001303	FOG: CBS domain [General function prediction only]; Region: COG0517
56110001304	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc; cd04612
56110001305	The C-terminal domain of a subfamily of Na+ /H+ antiporter existed in bacteria and archea . Na+/H+ exchange proteins eject protons from cells, effectively eliminating excess acid from actively metabolising cells. Na+ /H+ exchange activity is also crucial...; Region: Na_H_Antiporter_C; cd01988
56110001306	Ligand Binding Site [chemical binding]; other site
56110001307	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110001308	Ligand Binding Site [chemical binding]; other site
56110001309	hypothetical protein; Validated; Region: PRK07413
56110001310	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
56110001311	Walker A motif; other site
56110001312	homodimer interface [polypeptide binding]; other site
56110001313	ATP binding site [chemical binding]; other site
56110001314	hydroxycobalamin binding site [chemical binding]; other site
56110001315	Walker B motif; other site
56110001316	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
56110001317	Walker A motif; other site
56110001318	homodimer interface [polypeptide binding]; other site
56110001319	ATP binding site [chemical binding]; other site
56110001320	hydroxycobalamin binding site [chemical binding]; other site
56110001321	Walker B motif; other site
56110001322	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
56110001323	ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only]; Region: COG1606
56110001324	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_I; cd01990
56110001325	Ligand Binding Site [chemical binding]; other site
56110001326	Predicted membrane protein [Function unknown]; Region: COG3431
56110001327	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
56110001328	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110001329	dimer interface [polypeptide binding]; other site
56110001330	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110001331	putative CheW interface [polypeptide binding]; other site
56110001332	hybrid cluster protein; Provisional; Region: PRK05290
56110001333	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
56110001334	ACS interaction site; other site
56110001335	CODH interaction site; other site
56110001336	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
56110001337	hybrid metal cluster; other site
56110001338	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110001339	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110001340	ligand binding site [chemical binding]; other site
56110001341	flexible hinge region; other site
56110001342	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110001343	putative switch regulator; other site
56110001344	non-specific DNA interactions [nucleotide binding]; other site
56110001345	DNA binding site [nucleotide binding]
56110001346	sequence specific DNA binding site [nucleotide binding]; other site
56110001347	putative cAMP binding site [chemical binding]; other site
56110001348	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
56110001349	DNA binding residues [nucleotide binding]
56110001350	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110001351	active site
56110001352	ATP binding site [chemical binding]; other site
56110001353	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110001354	substrate binding site [chemical binding]; other site
56110001355	activation loop (A-loop); other site
56110001356	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110001357	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110001358	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110001359	putative active site [active]
56110001360	putative NTP binding site [chemical binding]; other site
56110001361	putative nucleic acid binding site [nucleotide binding]; other site
56110001362	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110001363	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110001364	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110001365	active site
56110001366	HEAT repeats; Region: HEAT_2; pfam13646
56110001367	HEAT repeats; Region: HEAT_2; pfam13646
56110001368	HEAT repeats; Region: HEAT_2; pfam13646
56110001369	HEAT repeats; Region: HEAT_2; pfam13646
56110001370	HEAT repeats; Region: HEAT_2; pfam13646
56110001371	S-layer homology domain; Region: SLH; pfam00395
56110001372	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
56110001373	Transcriptional regulator [Transcription]; Region: LysR; COG0583
56110001374	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
56110001375	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
56110001376	dimerization interface [polypeptide binding]; other site
56110001377	hypothetical protein; Provisional; Region: PRK07394
56110001378	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
56110001379	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
56110001380	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
56110001381	GTP binding site; other site
56110001382	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110001383	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110001384	active site
56110001385	phosphorylation site [posttranslational modification]
56110001386	intermolecular recognition site; other site
56110001387	dimerization interface [polypeptide binding]; other site
56110001388	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110001389	DNA binding site [nucleotide binding]
56110001390	geranylgeranyl reductase; Region: ChlP; TIGR02028
56110001391	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
56110001392	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
56110001393	Haemolytic domain; Region: Haemolytic; cl00506
56110001394	Response regulator receiver domain; Region: Response_reg; pfam00072
56110001395	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110001396	active site
56110001397	phosphorylation site [posttranslational modification]
56110001398	intermolecular recognition site; other site
56110001399	dimerization interface [polypeptide binding]; other site
56110001400	PAS domain S-box; Region: sensory_box; TIGR00229
56110001401	PAS domain S-box; Region: sensory_box; TIGR00229
56110001402	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110001403	putative active site [active]
56110001404	heme pocket [chemical binding]; other site
56110001405	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110001406	cyclase homology domain; Region: CHD; cd07302
56110001407	nucleotidyl binding site; other site
56110001408	metal binding site [ion binding]; metal-binding site
56110001409	dimer interface [polypeptide binding]; other site
56110001410	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
56110001411	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_20; cd08519
56110001412	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
56110001413	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110001414	dimer interface [polypeptide binding]; other site
56110001415	conserved gate region; other site
56110001416	ABC-ATPase subunit interface; other site
56110001417	TPR repeat; Region: TPR_11; pfam13414
56110001418	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001419	binding surface
56110001420	TPR motif; other site
56110001421	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001422	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001423	binding surface
56110001424	TPR motif; other site
56110001425	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110001426	This family is most closely related to the GT1 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide; Region: GT1_Bme6_like; cd03821
56110001427	putative ADP-binding pocket [chemical binding]; other site
56110001428	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
56110001429	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110001430	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
56110001431	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
56110001432	Probable Catalytic site; other site
56110001433	metal-binding site
56110001434	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
56110001435	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14317
56110001436	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
56110001437	active site
56110001438	substrate binding site [chemical binding]; other site
56110001439	metal binding site [ion binding]; metal-binding site
56110001440	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
56110001441	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110001442	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
56110001443	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
56110001444	Probable Catalytic site; other site
56110001445	metal-binding site
56110001446	G1P_TT_long represents the long form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_long; cd04189
56110001447	glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208
56110001448	substrate binding site; other site
56110001449	metal-binding site
56110001450	Oligomer interface; other site
56110001451	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
56110001452	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
56110001453	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
56110001454	NADP binding site [chemical binding]; other site
56110001455	active site
56110001456	putative substrate binding site [chemical binding]; other site
56110001457	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
56110001458	CHASE domain; Region: CHASE; cl01369
56110001459	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110001460	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110001461	dimer interface [polypeptide binding]; other site
56110001462	phosphorylation site [posttranslational modification]
56110001463	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110001464	ATP binding site [chemical binding]; other site
56110001465	Mg2+ binding site [ion binding]; other site
56110001466	G-X-G motif; other site
56110001467	Response regulator receiver domain; Region: Response_reg; pfam00072
56110001468	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110001469	active site
56110001470	phosphorylation site [posttranslational modification]
56110001471	intermolecular recognition site; other site
56110001472	dimerization interface [polypeptide binding]; other site
56110001473	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110001474	cyclase homology domain; Region: CHD; cd07302
56110001475	nucleotidyl binding site; other site
56110001476	metal binding site [ion binding]; metal-binding site
56110001477	dimer interface [polypeptide binding]; other site
56110001478	PIN domain; Region: PIN_3; cl17397
56110001479	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
56110001480	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
56110001481	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110001482	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110001483	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110001484	ligand binding site [chemical binding]; other site
56110001485	flexible hinge region; other site
56110001486	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
56110001487	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cd02259
56110001488	putative active site [active]
56110001489	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110001490	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
56110001491	Walker A/P-loop; other site
56110001492	ATP binding site [chemical binding]; other site
56110001493	Q-loop/lid; other site
56110001494	ABC transporter signature motif; other site
56110001495	Walker B; other site
56110001496	D-loop; other site
56110001497	H-loop/switch region; other site
56110001498	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
56110001499	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
56110001500	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
56110001501	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
56110001502	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
56110001503	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
56110001504	GDP-Fucose binding site [chemical binding]; other site
56110001505	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
56110001506	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110001507	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110001508	S-adenosylmethionine binding site [chemical binding]; other site
56110001509	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110001510	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110001511	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110001512	TPR repeat; Region: TPR_11; pfam13414
56110001513	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001514	binding surface
56110001515	TPR motif; other site
56110001516	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
56110001517	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001518	binding surface
56110001519	TPR motif; other site
56110001520	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001521	binding surface
56110001522	TPR motif; other site
56110001523	Protein of unknown function (DUF3288); Region: DUF3288; pfam11691
56110001524	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110001525	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110001526	active site
56110001527	Methyltransferase domain; Region: Methyltransf_24; pfam13578
56110001528	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
56110001529	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110001530	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
56110001531	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110001532	S-adenosylmethionine binding site [chemical binding]; other site
56110001533	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110001534	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110001535	NAD(P) binding site [chemical binding]; other site
56110001536	active site
56110001537	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
56110001538	Putative zinc binding domain; Region: Methyltransf_13; pfam08421
56110001539	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110001540	Methyltransferase domain; Region: Methyltransf_12; pfam08242
56110001541	C-methyltransferase C-terminal domain; Region: Methyltransf_14; pfam08484
56110001542	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
56110001543	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110001544	NAD(P) binding site [chemical binding]; other site
56110001545	active site
56110001546	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
56110001547	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
56110001548	substrate binding site; other site
56110001549	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
56110001550	Cation efflux family; Region: Cation_efflux; cl00316
56110001551	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110001552	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110001553	active site
56110001554	ATP binding site [chemical binding]; other site
56110001555	substrate binding site [chemical binding]; other site
56110001556	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110001557	substrate binding site [chemical binding]; other site
56110001558	activation loop (A-loop); other site
56110001559	activation loop (A-loop); other site
56110001560	AAA ATPase domain; Region: AAA_16; pfam13191
56110001561	Predicted ATPase [General function prediction only]; Region: COG3899
56110001562	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110001563	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110001564	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110001565	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110001566	dimer interface [polypeptide binding]; other site
56110001567	phosphorylation site [posttranslational modification]
56110001568	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110001569	ATP binding site [chemical binding]; other site
56110001570	Mg2+ binding site [ion binding]; other site
56110001571	G-X-G motif; other site
56110001572	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
56110001573	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
56110001574	acyl-activating enzyme (AAE) consensus motif; other site
56110001575	AMP binding site [chemical binding]; other site
56110001576	PilZ domain; Region: PilZ; pfam07238
56110001577	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
56110001578	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110001579	Condensation domain; Region: Condensation; pfam00668
56110001580	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110001581	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110001582	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110001583	acyl-activating enzyme (AAE) consensus motif; other site
56110001584	AMP binding site [chemical binding]; other site
56110001585	PilZ domain; Region: PilZ; pfam07238
56110001586	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
56110001587	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110001588	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
56110001589	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
56110001590	active site
56110001591	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110001592	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
56110001593	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110001594	S-adenosylmethionine binding site [chemical binding]; other site
56110001595	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110001596	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
56110001597	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110001598	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
56110001599	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
56110001600	active site
56110001601	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
56110001602	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
56110001603	substrate binding site [chemical binding]; other site
56110001604	ATP binding site [chemical binding]; other site
56110001605	Predicted methyltransferases [General function prediction only]; Region: COG0313
56110001606	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
56110001607	putative SAM binding site [chemical binding]; other site
56110001608	putative homodimer interface [polypeptide binding]; other site
56110001609	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110001610	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110001611	Domain of unknown function DUF21; Region: DUF21; pfam01595
56110001612	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
56110001613	FOG: CBS domain [General function prediction only]; Region: COG0517
56110001614	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
56110001615	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
56110001616	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110001617	FeS/SAM binding site; other site
56110001618	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
56110001619	DEAD-like helicases superfamily; Region: DEXDc; smart00487
56110001620	ATP binding site [chemical binding]; other site
56110001621	Mg++ binding site [ion binding]; other site
56110001622	motif III; other site
56110001623	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110001624	nucleotide binding region [chemical binding]; other site
56110001625	ATP-binding site [chemical binding]; other site
56110001626	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110001627	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110001628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110001629	S-adenosylmethionine binding site [chemical binding]; other site
56110001630	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110001631	PAS fold; Region: PAS_3; pfam08447
56110001632	putative active site [active]
56110001633	heme pocket [chemical binding]; other site
56110001634	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110001635	putative active site [active]
56110001636	PAS fold; Region: PAS_3; pfam08447
56110001637	heme pocket [chemical binding]; other site
56110001638	PAS domain; Region: PAS_9; pfam13426
56110001639	PAS fold; Region: PAS_4; pfam08448
56110001640	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110001641	putative active site [active]
56110001642	heme pocket [chemical binding]; other site
56110001643	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110001644	PAS fold; Region: PAS_3; pfam08447
56110001645	putative active site [active]
56110001646	heme pocket [chemical binding]; other site
56110001647	PAS domain; Region: PAS_9; pfam13426
56110001648	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110001649	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110001650	dimer interface [polypeptide binding]; other site
56110001651	phosphorylation site [posttranslational modification]
56110001652	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110001653	ATP binding site [chemical binding]; other site
56110001654	Mg2+ binding site [ion binding]; other site
56110001655	G-X-G motif; other site
56110001656	Response regulator receiver domain; Region: Response_reg; pfam00072
56110001657	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110001658	active site
56110001659	phosphorylation site [posttranslational modification]
56110001660	intermolecular recognition site; other site
56110001661	dimerization interface [polypeptide binding]; other site
56110001662	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110001663	cyclase homology domain; Region: CHD; cd07302
56110001664	nucleotidyl binding site; other site
56110001665	metal binding site [ion binding]; metal-binding site
56110001666	dimer interface [polypeptide binding]; other site
56110001667	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001668	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001669	binding surface
56110001670	TPR motif; other site
56110001671	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001672	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001673	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001674	binding surface
56110001675	TPR motif; other site
56110001676	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001677	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001678	binding surface
56110001679	TPR motif; other site
56110001680	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001681	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001682	binding surface
56110001683	TPR motif; other site
56110001684	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001685	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001686	Tetratricopeptide repeat; Region: TPR_10; pfam13374
56110001687	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001688	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110001689	binding surface
56110001690	TPR motif; other site
56110001691	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001692	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110001693	CHAT domain; Region: CHAT; cl17868
56110001694	CHAT domain; Region: CHAT; pfam12770
56110001695	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
56110001696	AAA domain; Region: AAA_23; pfam13476
56110001697	Walker A/P-loop; other site
56110001698	ATP binding site [chemical binding]; other site
56110001699	Q-loop/lid; other site
56110001700	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
56110001701	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110001702	ABC transporter signature motif; other site
56110001703	Walker B; other site
56110001704	D-loop; other site
56110001705	H-loop/switch region; other site
56110001706	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
56110001707	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110001708	active site
56110001709	metal binding site [ion binding]; metal-binding site
56110001710	DNA binding site [nucleotide binding]
56110001711	CAAX protease self-immunity; Region: Abi; pfam02517
56110001712	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
56110001713	Beta-propeller repeat; Region: SBBP; pfam06739
56110001714	Beta-propeller repeat; Region: SBBP; pfam06739
56110001715	Beta-propeller repeat; Region: SBBP; pfam06739
56110001716	Beta-propeller repeat; Region: SBBP; pfam06739
56110001717	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
56110001718	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
56110001719	putative active site [active]
56110001720	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
56110001721	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
56110001722	tRNA; other site
56110001723	putative tRNA binding site [nucleotide binding]; other site
56110001724	putative NADP binding site [chemical binding]; other site
56110001725	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
56110001726	hypothetical protein; Provisional; Region: PRK02509
56110001727	Uncharacterized conserved protein [Function unknown]; Region: COG1615
56110001728	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14096
56110001729	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
56110001730	active site
56110001731	dimer interface [polypeptide binding]; other site
56110001732	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
56110001733	dimer interface [polypeptide binding]; other site
56110001734	active site
56110001735	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110001736	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110001737	active site
56110001738	phosphorylation site [posttranslational modification]
56110001739	intermolecular recognition site; other site
56110001740	dimerization interface [polypeptide binding]; other site
56110001741	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110001742	DNA binding residues [nucleotide binding]
56110001743	dimerization interface [polypeptide binding]; other site
56110001744	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
56110001745	classical (c) SDRs; Region: SDR_c; cd05233
56110001746	NAD(P) binding site [chemical binding]; other site
56110001747	active site
56110001748	enoyl-CoA hydratase; Region: PLN02600
56110001749	Predicted membrane protein [Function unknown]; Region: COG4270
56110001750	Protein of unknown function DUF72; Region: DUF72; pfam01904
56110001751	Domain of unknown function (DUF4297); Region: DUF4297; pfam14130
56110001752	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
56110001753	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
56110001754	S-formylglutathione hydrolase; Region: PLN02442
56110001755	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
56110001756	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
56110001757	substrate binding site [chemical binding]; other site
56110001758	catalytic Zn binding site [ion binding]; other site
56110001759	NAD binding site [chemical binding]; other site
56110001760	structural Zn binding site [ion binding]; other site
56110001761	dimer interface [polypeptide binding]; other site
56110001762	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
56110001763	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
56110001764	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
56110001765	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110001766	putative PBP binding loops; other site
56110001767	dimer interface [polypeptide binding]; other site
56110001768	ABC-ATPase subunit interface; other site
56110001769	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
56110001770	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110001771	non-specific DNA binding site [nucleotide binding]; other site
56110001772	salt bridge; other site
56110001773	sequence-specific DNA binding site [nucleotide binding]; other site
56110001774	PBP superfamily domain; Region: PBP_like; pfam12727
56110001775	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
56110001776	Low molecular weight phosphatase family; Region: LMWPc; cd00115
56110001777	active site
56110001778	hypothetical protein; Validated; Region: PRK00153
56110001779	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
56110001780	FAD binding domain; Region: FAD_binding_4; pfam01565
56110001781	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
56110001782	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
56110001783	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
56110001784	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
56110001785	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
56110001786	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
56110001787	nicotinate (nicotinamide) nucleotide adenylyltransferase; Region: TIGR00482
56110001788	active site
56110001789	(T/H)XGH motif; other site
56110001790	glyceraldehyde-3-phosphate dehydrogenase; Reviewed; Region: PRK07403
56110001791	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
56110001792	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
56110001793	thiamine monophosphate kinase; Provisional; Region: PRK05731
56110001794	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
56110001795	ATP binding site [chemical binding]; other site
56110001796	dimerization interface [polypeptide binding]; other site
56110001797	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
56110001798	Transposase [DNA replication, recombination, and repair]; Region: COG5421
56110001799	cyclophilin_TLP40_like: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) similar ot the Spinach thylakoid lumen protein TLP40. Compared to the archetypal cyclophilin Human cyclophilin A, these proteins have similar peptidylprolyl...; Region: cyclophilin_TLP40_like; cd01924
56110001800	active site
56110001801	elongation factor P; Validated; Region: PRK00529
56110001802	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
56110001803	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
56110001804	RNA binding site [nucleotide binding]; other site
56110001805	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
56110001806	RNA binding site [nucleotide binding]; other site
56110001807	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
56110001808	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
56110001809	carboxyltransferase (CT) interaction site; other site
56110001810	biotinylation site [posttranslational modification]; other site
56110001811	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110001812	dimerization interface [polypeptide binding]; other site
56110001813	putative DNA binding site [nucleotide binding]; other site
56110001814	putative Zn2+ binding site [ion binding]; other site
56110001815	Sporulation and spore germination; Region: Germane; pfam10646
56110001816	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
56110001817	HEAT repeats; Region: HEAT_2; pfam13646
56110001818	HEAT repeats; Region: HEAT_2; pfam13646
56110001819	HEAT repeats; Region: HEAT_2; pfam13646
56110001820	HEAT repeats; Region: HEAT_2; pfam13646
56110001821	HEAT repeats; Region: HEAT_2; pfam13646
56110001822	HEAT repeats; Region: HEAT_2; pfam13646
56110001823	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
56110001824	prolyl-tRNA synthetase; Provisional; Region: PRK09194
56110001825	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
56110001826	dimer interface [polypeptide binding]; other site
56110001827	motif 1; other site
56110001828	active site
56110001829	motif 2; other site
56110001830	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
56110001831	putative deacylase active site [active]
56110001832	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
56110001833	active site
56110001834	motif 3; other site
56110001835	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
56110001836	anticodon binding site; other site
56110001837	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
56110001838	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
56110001839	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110001840	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110001841	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110001842	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
56110001843	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
56110001844	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
56110001845	Acetoacetate decarboxylase (ADC); Region: ADC; cl01919
56110001846	4-alpha-glucanotransferase; Provisional; Region: PRK14508
56110001847	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110001848	putative active site [active]
56110001849	Tubulin like; Region: Tubulin_2; pfam13809
56110001850	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
56110001851	Double zinc ribbon; Region: DZR; pfam12773
56110001852	Putative restriction endonuclease; Region: Uma2; pfam05685
56110001853	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110001854	putative active site [active]
56110001855	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
56110001856	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
56110001857	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110001858	Lamin Tail Domain; Region: LTD; pfam00932
56110001859	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
56110001860	Cadherin repeat-like domain; Region: CA_like; cl15786
56110001861	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110001862	Integral membrane protein DUF92; Region: DUF92; pfam01940
56110001863	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
56110001864	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
56110001865	active site
56110001866	metal binding site [ion binding]; metal-binding site
56110001867	Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075
56110001868	Lipase (class 2); Region: Lipase_2; pfam01674
56110001869	RNA methyltransferase, RsmE family; Region: TIGR00046
56110001870	RNA methyltransferase; Region: Methyltrans_RNA; pfam04452
56110001871	Domain of unknown function (DUF389); Region: DUF389; pfam04087
56110001872	ferredoxin-sulfite reductase; Region: sir; TIGR02042
56110001873	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
56110001874	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
56110001875	GtrA-like protein; Region: GtrA; pfam04138
56110001876	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
56110001877	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
56110001878	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
56110001879	active site
56110001880	homodimer interface [polypeptide binding]; other site
56110001881	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
56110001882	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110001883	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
56110001884	4Fe-4S binding domain; Region: Fer4; pfam00037
56110001885	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
56110001886	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
56110001887	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
56110001888	Catalytic site [active]
56110001889	Domain of unknown function (DUF1825); Region: DUF1825; pfam08855
56110001890	Transglycosylase; Region: Transgly; pfam00912
56110001891	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
56110001892	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
56110001893	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
56110001894	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
56110001895	active site
56110001896	HIGH motif; other site
56110001897	dimer interface [polypeptide binding]; other site
56110001898	KMSKS motif; other site
56110001899	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
56110001900	active site
56110001901	dimer interface [polypeptide binding]; other site
56110001902	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
56110001903	Fe-S cluster binding site [ion binding]; other site
56110001904	active site
56110001905	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110001906	active site
56110001907	Transposase [DNA replication, recombination, and repair]; Region: COG5421
56110001908	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
56110001909	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
56110001910	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
56110001911	active site
56110001912	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
56110001913	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
56110001914	TPP-binding site; other site
56110001915	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
56110001916	PYR/PP interface [polypeptide binding]; other site
56110001917	dimer interface [polypeptide binding]; other site
56110001918	TPP binding site [chemical binding]; other site
56110001919	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
56110001920	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
56110001921	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
56110001922	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
56110001923	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182
56110001924	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
56110001925	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
56110001926	The C-terminal domain of a subfamily of Na+ /H+ antiporter existed in bacteria and archea . Na+/H+ exchange proteins eject protons from cells, effectively eliminating excess acid from actively metabolising cells. Na+ /H+ exchange activity is also crucial...; Region: Na_H_Antiporter_C; cd01988
56110001927	Ligand Binding Site [chemical binding]; other site
56110001928	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110001929	Ligand Binding Site [chemical binding]; other site
56110001930	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110001931	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110001932	Cornifin (SPRR) family; Region: Cornifin; pfam02389
56110001933	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110001934	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110001935	Sensory domain found in DIguanylate Cyclases & Two-component systems; Region: DICT; cl01731
56110001936	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
56110001937	HD domain; Region: HD_5; pfam13487
56110001938	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110001939	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001940	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001941	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110001942	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001943	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001944	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
56110001945	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
56110001946	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cl01898
56110001947	putative active site [active]
56110001948	Predicted aspartyl protease [Posttranslational modification, protein turnover, chaperones]; Region: COG5550; cl17622
56110001949	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001950	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001951	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110001952	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110001953	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
56110001954	NAD(P) binding pocket [chemical binding]; other site
56110001955	Protein of unknown function (DUF2997); Region: DUF2997; pfam11211
56110001956	Ycf35; Provisional; Region: ycf35; CHL00193
56110001957	4Fe-4S single cluster domain; Region: Fer4_15; pfam13459
56110001958	yiaA/B two helix domain; Region: YiaAB; cl01759
56110001959	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
56110001960	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
56110001961	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
56110001962	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
56110001963	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110001964	Walker A motif; other site
56110001965	ATP binding site [chemical binding]; other site
56110001966	Walker B motif; other site
56110001967	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
56110001968	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
56110001969	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110001970	Walker A motif; other site
56110001971	ATP binding site [chemical binding]; other site
56110001972	Walker B motif; other site
56110001973	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
56110001974	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
56110001975	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110001976	DNA binding residues [nucleotide binding]
56110001977	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110001978	HEAT repeats; Region: HEAT_2; pfam13646
56110001979	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110001980	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
56110001981	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
56110001982	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
56110001983	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
56110001984	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110001985	motif II; other site
56110001986	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
56110001987	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
56110001988	DHH family; Region: DHH; pfam01368
56110001989	DHHA1 domain; Region: DHHA1; pfam02272
56110001990	Uncharacterized conserved protein [Function unknown]; Region: COG1434
56110001991	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
56110001992	putative active site [active]
56110001993	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
56110001994	C-terminal peptidase (prc); Region: prc; TIGR00225
56110001995	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
56110001996	protein binding site [polypeptide binding]; other site
56110001997	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
56110001998	Catalytic dyad [active]
56110001999	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110002000	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
56110002001	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
56110002002	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
56110002003	MPT binding site; other site
56110002004	trimer interface [polypeptide binding]; other site
56110002005	photosystem II reaction center protein Psb28; Provisional; Region: PRK13612
56110002006	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
56110002007	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
56110002008	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110002009	catalytic residues [active]
56110002010	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK08649
56110002011	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
56110002012	active site
56110002013	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
56110002014	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
56110002015	active site
56110002016	metal binding site [ion binding]; metal-binding site
56110002017	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002018	putative active site [active]
56110002019	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002020	putative active site [active]
56110002021	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
56110002022	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
56110002023	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110002024	dimer interface [polypeptide binding]; other site
56110002025	conserved gate region; other site
56110002026	putative PBP binding loops; other site
56110002027	ABC-ATPase subunit interface; other site
56110002028	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
56110002029	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110002030	dimer interface [polypeptide binding]; other site
56110002031	conserved gate region; other site
56110002032	putative PBP binding loops; other site
56110002033	ABC-ATPase subunit interface; other site
56110002034	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
56110002035	The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513
56110002036	peptide binding site [polypeptide binding]; other site
56110002037	dimer interface [polypeptide binding]; other site
56110002038	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
56110002039	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
56110002040	tetramer interface [polypeptide binding]; other site
56110002041	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110002042	catalytic residue [active]
56110002043	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
56110002044	active site
56110002045	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
56110002046	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
56110002047	MAPEG family; Region: MAPEG; pfam01124
56110002048	GUN4-like; Region: GUN4; pfam05419
56110002049	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
56110002050	HflK protein; Region: hflK; TIGR01933
56110002051	5-oxoprolinase; Region: PLN02666
56110002052	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
56110002053	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
56110002054	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
56110002055	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
56110002056	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
56110002057	active site
56110002058	catalytic site [active]
56110002059	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
56110002060	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110002061	ATP binding site [chemical binding]; other site
56110002062	putative Mg++ binding site [ion binding]; other site
56110002063	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110002064	nucleotide binding region [chemical binding]; other site
56110002065	ATP-binding site [chemical binding]; other site
56110002066	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
56110002067	Cell division initiation protein [Cell division and chromosome partitioning]; Region: DivIVA; COG3599
56110002068	Peptidase family M48; Region: Peptidase_M48; pfam01435
56110002069	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
56110002070	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110002071	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110002072	Walker A/P-loop; other site
56110002073	ATP binding site [chemical binding]; other site
56110002074	Q-loop/lid; other site
56110002075	ABC transporter signature motif; other site
56110002076	Walker B; other site
56110002077	D-loop; other site
56110002078	H-loop/switch region; other site
56110002079	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110002080	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110002081	Predicted esterase [General function prediction only]; Region: COG0400
56110002082	putative hydrolase; Provisional; Region: PRK11460
56110002083	Protein of unknown function (DUF2555); Region: DUF2555; pfam10742
56110002084	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
56110002085	Flavoprotein; Region: Flavoprotein; pfam02441
56110002086	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
56110002087	Protein of unknown function (DUF4090); Region: DUF4090; pfam13319
56110002088	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002089	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002090	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002091	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002092	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
56110002093	Amidinotransferase; Region: Amidinotransf; cl12043
56110002094	Uncharacterized conserved protein [Function unknown]; Region: COG1915
56110002095	Saccharopine dehydrogenase N-terminal domain; Region: SDH_N_domain; cd12144
56110002096	homodimer interface [polypeptide binding]; other site
56110002097	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
56110002098	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110002099	active site
56110002100	motif I; other site
56110002101	motif II; other site
56110002102	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002103	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110002104	putative active site [active]
56110002105	heme pocket [chemical binding]; other site
56110002106	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110002107	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002108	putative active site [active]
56110002109	heme pocket [chemical binding]; other site
56110002110	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002111	putative active site [active]
56110002112	heme pocket [chemical binding]; other site
56110002113	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002114	PAS fold; Region: PAS_3; pfam08447
56110002115	putative active site [active]
56110002116	heme pocket [chemical binding]; other site
56110002117	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002118	putative active site [active]
56110002119	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110002120	heme pocket [chemical binding]; other site
56110002121	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002122	putative active site [active]
56110002123	heme pocket [chemical binding]; other site
56110002124	PAS domain S-box; Region: sensory_box; TIGR00229
56110002125	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002126	putative active site [active]
56110002127	heme pocket [chemical binding]; other site
56110002128	PAS fold; Region: PAS_4; pfam08448
56110002129	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110002130	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110002131	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110002132	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110002133	dimer interface [polypeptide binding]; other site
56110002134	phosphorylation site [posttranslational modification]
56110002135	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110002136	ATP binding site [chemical binding]; other site
56110002137	Mg2+ binding site [ion binding]; other site
56110002138	G-X-G motif; other site
56110002139	Protein of unknown function, DUF488; Region: DUF488; pfam04343
56110002140	Protein of unknown function, DUF488; Region: DUF488; pfam04343
56110002141	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
56110002142	Cadherin repeat-like domain; Region: CA_like; cl15786
56110002143	Ca2+ binding site [ion binding]; other site
56110002144	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110002145	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002146	putative active site [active]
56110002147	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
56110002148	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002149	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002150	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002151	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002152	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002153	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002154	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002155	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002156	FOG: CBS domain [General function prediction only]; Region: COG0517
56110002157	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_17; cd04630
56110002158	CP12 domain; Region: CP12; pfam02672
56110002159	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002160	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110002161	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002162	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002163	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002164	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002165	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002166	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002167	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002168	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002169	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110002170	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002171	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002172	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002173	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002174	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002175	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
56110002176	Leucine rich repeat; Region: LRR_8; pfam13855
56110002177	Leucine-rich repeats; other site
56110002178	Leucine rich repeat; Region: LRR_8; pfam13855
56110002179	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110002180	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
56110002181	G1 box; other site
56110002182	GTP/Mg2+ binding site [chemical binding]; other site
56110002183	G2 box; other site
56110002184	Switch I region; other site
56110002185	G3 box; other site
56110002186	Switch II region; other site
56110002187	G4 box; other site
56110002188	G5 box; other site
56110002189	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
56110002190	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
56110002191	putative active site [active]
56110002192	homotetrameric interface [polypeptide binding]; other site
56110002193	metal binding site [ion binding]; metal-binding site
56110002194	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
56110002195	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
56110002196	ring oligomerisation interface [polypeptide binding]; other site
56110002197	ATP/Mg binding site [chemical binding]; other site
56110002198	stacking interactions; other site
56110002199	hinge regions; other site
56110002200	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
56110002201	oligomerisation interface [polypeptide binding]; other site
56110002202	mobile loop; other site
56110002203	roof hairpin; other site
56110002204	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
56110002205	dimer interface [polypeptide binding]; other site
56110002206	[2Fe-2S] cluster binding site [ion binding]; other site
56110002207	response regulator FixJ; Provisional; Region: fixJ; PRK09390
56110002208	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110002209	active site
56110002210	phosphorylation site [posttranslational modification]
56110002211	intermolecular recognition site; other site
56110002212	dimerization interface [polypeptide binding]; other site
56110002213	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110002214	DNA binding residues [nucleotide binding]
56110002215	dimerization interface [polypeptide binding]; other site
56110002216	Uncharacterized conserved protein [Function unknown]; Region: COG1432
56110002217	LabA_like proteins; Region: LabA; cd10911
56110002218	putative metal binding site [ion binding]; other site
56110002219	2-isopropylmalate synthase; Validated; Region: PRK00915
56110002220	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
56110002221	active site
56110002222	catalytic residues [active]
56110002223	metal binding site [ion binding]; metal-binding site
56110002224	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
56110002225	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002226	putative active site [active]
56110002227	M28 Zn-Peptidases; Region: M28_like_1; cd05640
56110002228	Peptidase family M28; Region: Peptidase_M28; pfam04389
56110002229	metal binding site [ion binding]; metal-binding site
56110002230	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110002231	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110002232	active site
56110002233	phosphorylation site [posttranslational modification]
56110002234	intermolecular recognition site; other site
56110002235	dimerization interface [polypeptide binding]; other site
56110002236	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110002237	DNA binding residues [nucleotide binding]
56110002238	dimerization interface [polypeptide binding]; other site
56110002239	Response regulator receiver domain; Region: Response_reg; pfam00072
56110002240	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110002241	active site
56110002242	phosphorylation site [posttranslational modification]
56110002243	intermolecular recognition site; other site
56110002244	dimerization interface [polypeptide binding]; other site
56110002245	Protein of unknown function (DUF2721); Region: DUF2721; pfam11026
56110002246	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
56110002247	Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]; Region: COG2138
56110002248	putative active site [active]
56110002249	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), C-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_C; cd03414
56110002250	putative active site [active]
56110002251	Member of the Rhodanese Homology Domain superfamily, subgroup 2. Subgroup 2 includes uncharacterized putative rhodanese-related domains; Region: RHOD_2; cd01528
56110002252	active site residue [active]
56110002253	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110002254	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110002255	active site
56110002256	ATP binding site [chemical binding]; other site
56110002257	substrate binding site [chemical binding]; other site
56110002258	activation loop (A-loop); other site
56110002259	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110002260	GUN4-like; Region: GUN4; pfam05419
56110002261	Domain of unknown function (DUF4359); Region: DUF4359; pfam14271
56110002262	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
56110002263	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
56110002264	RNA binding surface [nucleotide binding]; other site
56110002265	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
56110002266	active site
56110002267	LabA_like proteins; Region: LabA_like; cd06167
56110002268	putative metal binding site [ion binding]; other site
56110002269	Uncharacterized conserved protein [Function unknown]; Region: COG1432
56110002270	ribonuclease III; Reviewed; Region: rnc; PRK00102
56110002271	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
56110002272	dimerization interface [polypeptide binding]; other site
56110002273	active site
56110002274	metal binding site [ion binding]; metal-binding site
56110002275	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
56110002276	dsRNA binding site [nucleotide binding]; other site
56110002277	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
56110002278	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
56110002279	catalytic residues [active]
56110002280	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
56110002281	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
56110002282	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
56110002283	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
56110002284	glycogen branching enzyme; Provisional; Region: PRK05402
56110002285	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
56110002286	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
56110002287	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
56110002288	active site
56110002289	catalytic site [active]
56110002290	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
56110002291	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
56110002292	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
56110002293	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
56110002294	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
56110002295	heat shock protein 90; Provisional; Region: PRK05218
56110002296	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110002297	ATP binding site [chemical binding]; other site
56110002298	Mg2+ binding site [ion binding]; other site
56110002299	G-X-G motif; other site
56110002300	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
56110002301	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110002302	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110002303	active site
56110002304	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110002305	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110002306	active site
56110002307	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110002308	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110002309	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110002310	active site
56110002311	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
56110002312	Clp amino terminal domain; Region: Clp_N; pfam02861
56110002313	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110002314	Walker A motif; other site
56110002315	ATP binding site [chemical binding]; other site
56110002316	Walker B motif; other site
56110002317	arginine finger; other site
56110002318	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110002319	Walker A motif; other site
56110002320	ATP binding site [chemical binding]; other site
56110002321	Walker B motif; other site
56110002322	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
56110002323	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
56110002324	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
56110002325	dimer interface [polypeptide binding]; other site
56110002326	active site
56110002327	metal binding site [ion binding]; metal-binding site
56110002328	glutathione binding site [chemical binding]; other site
56110002329	enolase; Provisional; Region: eno; PRK00077
56110002330	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
56110002331	dimer interface [polypeptide binding]; other site
56110002332	metal binding site [ion binding]; metal-binding site
56110002333	substrate binding pocket [chemical binding]; other site
56110002334	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
56110002335	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
56110002336	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110002337	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
56110002338	Coenzyme A binding pocket [chemical binding]; other site
56110002339	Fragile site-associated protein C-terminus; Region: FSA_C; pfam10479
56110002340	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110002341	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
56110002342	UGMP family protein; Validated; Region: PRK09604
56110002343	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
56110002344	Photosystem I reaction centre subunit III; Region: PSI_PsaF; cl03627
56110002345	Photosystem I reaction centre subunit IX / PsaJ; Region: PSI_PsaJ; cl03320
56110002346	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
56110002347	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
56110002348	catalytic site [active]
56110002349	G-X2-G-X-G-K; other site
56110002350	hypothetical protein; Provisional; Region: PRK04323
56110002351	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
56110002352	Domain of unknown function (DUF814); Region: DUF814; pfam05670
56110002353	Domain of unknown function (DUF4415); Region: DUF4415; pfam14384
56110002354	Protein of unknown function (DUF497); Region: DUF497; cl01108
56110002355	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
56110002356	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
56110002357	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
56110002358	Protein of unknown function (DUF497); Region: DUF497; pfam04365
56110002359	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
56110002360	D-inositol-3-phosphate glycosyltransferase; Region: mycothiol_MshA; TIGR03449
56110002361	putative ADP-binding pocket [chemical binding]; other site
56110002362	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
56110002363	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
56110002364	23S rRNA binding site [nucleotide binding]; other site
56110002365	L21 binding site [polypeptide binding]; other site
56110002366	L13 binding site [polypeptide binding]; other site
56110002367	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
56110002368	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
56110002369	substrate binding pocket [chemical binding]; other site
56110002370	membrane-bound complex binding site; other site
56110002371	hinge residues; other site
56110002372	TPR repeat; Region: TPR_11; pfam13414
56110002373	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002374	binding surface
56110002375	TPR motif; other site
56110002376	TPR repeat; Region: TPR_11; pfam13414
56110002377	Late competence development protein ComFB; Region: ComFB; pfam10719
56110002378	CHASE domain; Region: CHASE; pfam03924
56110002379	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110002380	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002381	putative active site [active]
56110002382	heme pocket [chemical binding]; other site
56110002383	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002384	putative active site [active]
56110002385	heme pocket [chemical binding]; other site
56110002386	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110002387	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110002388	dimer interface [polypeptide binding]; other site
56110002389	phosphorylation site [posttranslational modification]
56110002390	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110002391	ATP binding site [chemical binding]; other site
56110002392	Mg2+ binding site [ion binding]; other site
56110002393	G-X-G motif; other site
56110002394	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
56110002395	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
56110002396	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110002397	S-adenosylmethionine binding site [chemical binding]; other site
56110002398	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110002399	Response regulator receiver domain; Region: Response_reg; pfam00072
56110002400	active site
56110002401	phosphorylation site [posttranslational modification]
56110002402	intermolecular recognition site; other site
56110002403	dimerization interface [polypeptide binding]; other site
56110002404	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110002405	GAF domain; Region: GAF; pfam01590
56110002406	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
56110002407	dimer interface [polypeptide binding]; other site
56110002408	ssDNA binding site [nucleotide binding]; other site
56110002409	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110002410	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002411	putative active site [active]
56110002412	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002413	putative active site [active]
56110002414	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002415	putative active site [active]
56110002416	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002417	putative active site [active]
56110002418	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
56110002419	Drosophila melanogaster CG11883 and related proteins, N-terminal metallophosphatase domain; Region: MPP_CG11883_N; cd07406
56110002420	putative active site [active]
56110002421	putative metal binding site [ion binding]; other site
56110002422	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
56110002423	Phycobilisome protein; Region: Phycobilisome; cl08227
56110002424	allophycocyanin beta subunit; Region: apcB; CHL00088
56110002425	CpcD/allophycocyanin linker domain; Region: CpcD; pfam01383
56110002426	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
56110002427	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cl01898
56110002428	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
56110002429	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
56110002430	c-type cytochrome biogenensis protein; Validated; Region: ccs1; CHL00177
56110002431	ResB-like family; Region: ResB; pfam05140
56110002432	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
56110002433	basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins; Region: B_zip1; cl02576
56110002434	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002435	PAS fold; Region: PAS_3; pfam08447
56110002436	putative active site [active]
56110002437	heme pocket [chemical binding]; other site
56110002438	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110002439	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002440	putative active site [active]
56110002441	heme pocket [chemical binding]; other site
56110002442	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110002443	dimer interface [polypeptide binding]; other site
56110002444	phosphorylation site [posttranslational modification]
56110002445	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110002446	ATP binding site [chemical binding]; other site
56110002447	Mg2+ binding site [ion binding]; other site
56110002448	G-X-G motif; other site
56110002449	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110002450	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110002451	active site
56110002452	phosphorylation site [posttranslational modification]
56110002453	intermolecular recognition site; other site
56110002454	dimerization interface [polypeptide binding]; other site
56110002455	PAS domain S-box; Region: sensory_box; TIGR00229
56110002456	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110002457	putative active site [active]
56110002458	heme pocket [chemical binding]; other site
56110002459	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110002460	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110002461	metal binding site [ion binding]; metal-binding site
56110002462	active site
56110002463	I-site; other site
56110002464	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110002465	Uncharacterized conserved protein [Function unknown]; Region: COG5607
56110002466	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110002467	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110002468	non-specific DNA interactions [nucleotide binding]; other site
56110002469	DNA binding site [nucleotide binding]
56110002470	sequence specific DNA binding site [nucleotide binding]; other site
56110002471	putative cAMP binding site [chemical binding]; other site
56110002472	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
56110002473	putative active site pocket [active]
56110002474	dimerization interface [polypeptide binding]; other site
56110002475	putative catalytic residue [active]
56110002476	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
56110002477	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
56110002478	nucleotide binding region [chemical binding]; other site
56110002479	ATP-binding site [chemical binding]; other site
56110002480	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cl00327
56110002481	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
56110002482	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
56110002483	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
56110002484	FtsX-like permease family; Region: FtsX; pfam02687
56110002485	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
56110002486	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
56110002487	FtsX-like permease family; Region: FtsX; pfam02687
56110002488	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
56110002489	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110002490	Protein of unknown function (DUF98); Region: DUF98; pfam01947
56110002491	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110002492	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
56110002493	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
56110002494	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110002495	WD domain, G-beta repeat; Region: WD40; pfam00400
56110002496	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110002497	structural tetrad; other site
56110002498	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110002499	structural tetrad; other site
56110002500	WD domain, G-beta repeat; Region: WD40; pfam00400
56110002501	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110002502	salt bridge; other site
56110002503	non-specific DNA binding site [nucleotide binding]; other site
56110002504	sequence-specific DNA binding site [nucleotide binding]; other site
56110002505	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110002506	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110002507	structural tetrad; other site
56110002508	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110002509	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110002510	structural tetrad; other site
56110002511	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110002512	structural tetrad; other site
56110002513	hypothetical protein; Validated; Region: PRK00110
56110002514	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
56110002515	beta-galactosidase; Region: BGL; TIGR03356
56110002516	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
56110002517	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
56110002518	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110002519	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
56110002520	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
56110002521	arginine-tRNA ligase; Region: PLN02286
56110002522	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
56110002523	active site
56110002524	HIGH motif; other site
56110002525	KMSK motif region; other site
56110002526	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
56110002527	tRNA binding surface [nucleotide binding]; other site
56110002528	anticodon binding site; other site
56110002529	pyridine nucleotide-disulfide oxidoreductase family protein; Region: Nterm_to_SelD; TIGR03169
56110002530	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110002531	pyruvate dehydrogenase E1 component alpha subunit; Reviewed; Region: odpA; CHL00149
56110002532	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
56110002533	tetramer interface [polypeptide binding]; other site
56110002534	TPP-binding site [chemical binding]; other site
56110002535	heterodimer interface [polypeptide binding]; other site
56110002536	phosphorylation loop region [posttranslational modification]
56110002537	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110002538	HSP70 interaction site [polypeptide binding]; other site
56110002539	Protein of unknown function (DUF4101); Region: DUF4101; pfam13355
56110002540	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
56110002541	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3330
56110002542	Uncharacterized conserved protein (DUF2358); Region: DUF2358; pfam10184
56110002543	Anion-transporting ATPase; Region: ArsA_ATPase; pfam02374
56110002544	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
56110002545	P loop; other site
56110002546	Nucleotide binding site [chemical binding]; other site
56110002547	DTAP/Switch II; other site
56110002548	Switch I; other site
56110002549	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
56110002550	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
56110002551	Protein of unknown function (DUF2281); Region: DUF2281; cl02355
56110002552	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
56110002553	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
56110002554	dimerization interface [polypeptide binding]; other site
56110002555	ATP binding site [chemical binding]; other site
56110002556	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
56110002557	dimerization interface [polypeptide binding]; other site
56110002558	ATP binding site [chemical binding]; other site
56110002559	amidophosphoribosyltransferase; Provisional; Region: PRK07349
56110002560	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
56110002561	active site
56110002562	tetramer interface [polypeptide binding]; other site
56110002563	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110002564	active site
56110002565	DnaJ-class molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: CbpA; COG2214
56110002566	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110002567	HSP70 interaction site [polypeptide binding]; other site
56110002568	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
56110002569	substrate binding site [polypeptide binding]; other site
56110002570	dimer interface [polypeptide binding]; other site
56110002571	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK02862
56110002572	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
56110002573	ligand binding site; other site
56110002574	oligomer interface; other site
56110002575	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
56110002576	dimer interface [polypeptide binding]; other site
56110002577	N-terminal domain interface [polypeptide binding]; other site
56110002578	sulfate 1 binding site; other site
56110002579	Glutamate-cysteine ligase family 2(GCS2); Region: GCS2; cl00954
56110002580	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
56110002581	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
56110002582	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110002583	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110002584	Protein of unknown function (DUF3593); Region: DUF3593; pfam12159
56110002585	Protein of unknown function (DUF2499); Region: DUF2499; pfam10693
56110002586	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
56110002587	polysaccharide pyruvyl transferase CsaB; Region: S_layer_CsaB; TIGR03609
56110002588	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110002589	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110002590	cell division protein; Validated; Region: ftsH; CHL00176
56110002591	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110002592	Walker A motif; other site
56110002593	ATP binding site [chemical binding]; other site
56110002594	Walker B motif; other site
56110002595	arginine finger; other site
56110002596	Peptidase family M41; Region: Peptidase_M41; pfam01434
56110002597	Protoheme ferro-lyase (ferrochelatase) [Coenzyme metabolism]; Region: HemH; COG0276
56110002598	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
56110002599	C-terminal domain interface [polypeptide binding]; other site
56110002600	active site
56110002601	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
56110002602	active site
56110002603	N-terminal domain interface [polypeptide binding]; other site
56110002604	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
56110002605	active site
56110002606	catalytic triad [active]
56110002607	oxyanion hole [active]
56110002608	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
56110002609	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
56110002610	active site
56110002611	catalytic tetrad [active]
56110002612	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
56110002613	tetramer (dimer of dimers) interface [polypeptide binding]; other site
56110002614	active site
56110002615	dimer interface [polypeptide binding]; other site
56110002616	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110002617	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110002618	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002619	TPR repeat; Region: TPR_11; pfam13414
56110002620	binding surface
56110002621	TPR motif; other site
56110002622	Mo-dependent nitrogenase C-terminus; Region: Mo-nitro_C; pfam06967
56110002623	Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; Region: HemeO; cd00232
56110002624	heme binding pocket [chemical binding]; other site
56110002625	heme ligand [chemical binding]; other site
56110002626	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
56110002627	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
56110002628	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
56110002629	active site
56110002630	ribulose/triose binding site [chemical binding]; other site
56110002631	phosphate binding site [ion binding]; other site
56110002632	substrate (anthranilate) binding pocket [chemical binding]; other site
56110002633	product (indole) binding pocket [chemical binding]; other site
56110002634	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
56110002635	homodimer interface [polypeptide binding]; other site
56110002636	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110002637	catalytic residue [active]
56110002638	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002639	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002640	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002641	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002642	Membrane protein of unknown function; Region: DUF360; pfam04020
56110002643	5'-methylthioadenosine phosphorylase; Provisional; Region: PRK07432
56110002644	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4339
56110002645	FAD binding domain; Region: FAD_binding_4; pfam01565
56110002646	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
56110002647	Methyltransferase domain; Region: Methyltransf_24; pfam13578
56110002648	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
56110002649	active site
56110002650	catalytic triad [active]
56110002651	oxyanion hole [active]
56110002652	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
56110002653	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
56110002654	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
56110002655	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110002656	Mg2+ binding site [ion binding]; other site
56110002657	G-X-G motif; other site
56110002658	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
56110002659	anchoring element; other site
56110002660	dimer interface [polypeptide binding]; other site
56110002661	ATP binding site [chemical binding]; other site
56110002662	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
56110002663	active site
56110002664	metal binding site [ion binding]; metal-binding site
56110002665	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110002666	protein-splicing catalytic site; other site
56110002667	thioester formation/cholesterol transfer; other site
56110002668	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110002669	non-specific DNA binding site [nucleotide binding]; other site
56110002670	salt bridge; other site
56110002671	sequence-specific DNA binding site [nucleotide binding]; other site
56110002672	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
56110002673	active site
56110002674	metal binding site [ion binding]; metal-binding site
56110002675	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
56110002676	Leucine rich repeat variant; Region: LRV; pfam01816
56110002677	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110002678	MoxR-like ATPases [General function prediction only]; Region: COG0714
56110002679	Walker A motif; other site
56110002680	ATP binding site [chemical binding]; other site
56110002681	Walker B motif; other site
56110002682	arginine finger; other site
56110002683	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3864
56110002684	Putative metallopeptidase domain; Region: DUF2201_N; pfam13203
56110002685	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
56110002686	metal ion-dependent adhesion site (MIDAS); other site
56110002687	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
56110002688	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
56110002689	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110002690	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110002691	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
56110002692	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110002693	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110002694	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
56110002695	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002696	putative active site [active]
56110002697	Protein of unknown function (DUF1092); Region: DUF1092; pfam06485
56110002698	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
56110002699	putative homodimer interface [polypeptide binding]; other site
56110002700	putative active site pocket [active]
56110002701	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
56110002702	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
56110002703	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110002704	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110002705	homodimer interface [polypeptide binding]; other site
56110002706	catalytic residue [active]
56110002707	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
56110002708	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
56110002709	putative di-iron ligands [ion binding]; other site
56110002710	Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of photorespiration. Rubisco...; Region: RuBisCO_small; cd03527
56110002711	multimerization interface [polypeptide binding]; other site
56110002712	RbcX protein; Region: RcbX; pfam02341
56110002713	ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Region: rbcL; CHL00040
56110002714	Ribulose bisphosphate carboxylase large chain, Form I; Region: RuBisCO_large_I; cd08212
56110002715	homodimer interface [polypeptide binding]; other site
56110002716	active site
56110002717	heterodimer interface [polypeptide binding]; other site
56110002718	catalytic residue [active]
56110002719	metal binding site [ion binding]; metal-binding site
56110002720	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110002721	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110002722	active site
56110002723	ATP binding site [chemical binding]; other site
56110002724	substrate binding site [chemical binding]; other site
56110002725	activation loop (A-loop); other site
56110002726	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110002727	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110002728	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
56110002729	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110002730	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110002731	binding surface
56110002732	TPR motif; other site
56110002733	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110002734	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
56110002735	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
56110002736	Homeodomain-like domain; Region: HTH_23; pfam13384
56110002737	Winged helix-turn helix; Region: HTH_29; pfam13551
56110002738	Winged helix-turn helix; Region: HTH_33; pfam13592
56110002739	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110002740	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110002741	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
56110002742	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
56110002743	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110002744	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110002745	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110002746	ligand binding site [chemical binding]; other site
56110002747	flexible hinge region; other site
56110002748	Uncharacterized conserved protein [Function unknown]; Region: COG1543
56110002749	N-terminal catalytic domain of  alpha-amylase ( AmyC ) and similar proteins; Region: GH57N_AmyC_like; cd10792
56110002750	active site
56110002751	substrate binding site [chemical binding]; other site
56110002752	catalytic site [active]
56110002753	Domain of unknown function (DUF1957); Region: DUF1957; pfam09210
56110002754	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110002755	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002756	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002757	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002758	binding surface
56110002759	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110002760	TPR motif; other site
56110002761	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002762	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002763	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002764	light-harvesting-like protein 3; Provisional; Region: PLN00014
56110002765	putative glycosyl transferase; Provisional; Region: PRK10307
56110002766	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
56110002767	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
56110002768	Zn2+ binding site [ion binding]; other site
56110002769	Mg2+ binding site [ion binding]; other site
56110002770	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
56110002771	Protein of unknown function (DUF1230); Region: DUF1230; pfam06799
56110002772	L-asparaginase II; Region: Asparaginase_II; cl01842
56110002773	proton extrusion protein PcxA; Provisional; Region: PRK02507
56110002774	putative acyl transferase; Provisional; Region: PRK10502
56110002775	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
56110002776	putative trimer interface [polypeptide binding]; other site
56110002777	putative active site [active]
56110002778	putative substrate binding site [chemical binding]; other site
56110002779	putative CoA binding site [chemical binding]; other site
56110002780	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
56110002781	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110002782	dimer interface [polypeptide binding]; other site
56110002783	conserved gate region; other site
56110002784	putative PBP binding loops; other site
56110002785	ABC-ATPase subunit interface; other site
56110002786	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
56110002787	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110002788	dimer interface [polypeptide binding]; other site
56110002789	conserved gate region; other site
56110002790	putative PBP binding loops; other site
56110002791	ABC-ATPase subunit interface; other site
56110002792	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
56110002793	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
56110002794	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
56110002795	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
56110002796	Walker A/P-loop; other site
56110002797	ATP binding site [chemical binding]; other site
56110002798	Q-loop/lid; other site
56110002799	ABC transporter signature motif; other site
56110002800	Walker B; other site
56110002801	D-loop; other site
56110002802	H-loop/switch region; other site
56110002803	TOBE domain; Region: TOBE_2; pfam08402
56110002804	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
56110002805	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110002806	protein-splicing catalytic site; other site
56110002807	thioester formation/cholesterol transfer; other site
56110002808	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110002809	protein-splicing catalytic site; other site
56110002810	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110002811	protein-splicing catalytic site; other site
56110002812	thioester formation/cholesterol transfer; other site
56110002813	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
56110002814	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
56110002815	AMP binding site [chemical binding]; other site
56110002816	metal binding site [ion binding]; metal-binding site
56110002817	active site
56110002818	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
56110002819	putative active site [active]
56110002820	transaldolase; Provisional; Region: PRK03903
56110002821	catalytic residue [active]
56110002822	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
56110002823	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
56110002824	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
56110002825	glucose-6-phosphate dehydrogenase assembly protein OpcA; Region: OpcA; TIGR00534
56110002826	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110002827	Glucose-6-phosphate dehydrogenase subunit; Region: OpcA_G6PD_assem; pfam10128
56110002828	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110002829	putative active site [active]
56110002830	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
56110002831	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
56110002832	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
56110002833	catalytic triad [active]
56110002834	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
56110002835	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
56110002836	Surface antigen; Region: Bac_surface_Ag; pfam01103
56110002837	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
56110002838	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110002839	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110002840	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
56110002841	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110002842	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110002843	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
56110002844	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110002845	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110002846	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110002847	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
56110002848	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110002849	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
56110002850	GSH binding site [chemical binding]; other site
56110002851	catalytic residues [active]
56110002852	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
56110002853	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
56110002854	nucleoside/Zn binding site; other site
56110002855	dimer interface [polypeptide binding]; other site
56110002856	catalytic motif [active]
56110002857	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
56110002858	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
56110002859	putative acyl-acceptor binding pocket; other site
56110002860	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
56110002861	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110002862	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110002863	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
56110002864	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110002865	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
56110002866	Peptidase S8 family domain, uncharacterized subfamily 15; Region: Peptidases_S8_15; cd07498
56110002867	active site
56110002868	catalytic triad [active]
56110002869	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
56110002870	BolA-like protein; Region: BolA; pfam01722
56110002871	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
56110002872	putative GSH binding site [chemical binding]; other site
56110002873	catalytic residues [active]
56110002874	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110002875	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110002876	active site
56110002877	phosphorylation site [posttranslational modification]
56110002878	intermolecular recognition site; other site
56110002879	dimerization interface [polypeptide binding]; other site
56110002880	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110002881	DNA binding site [nucleotide binding]
56110002882	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
56110002883	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
56110002884	Walker A/P-loop; other site
56110002885	ATP binding site [chemical binding]; other site
56110002886	Q-loop/lid; other site
56110002887	ABC transporter signature motif; other site
56110002888	Walker B; other site
56110002889	D-loop; other site
56110002890	H-loop/switch region; other site
56110002891	Protein of unknown function (DUF4079); Region: DUF4079; pfam13301
56110002892	Domain of unknown function (DUF1830); Region: DUF1830; pfam08865
56110002893	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
56110002894	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
56110002895	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110002896	FeS/SAM binding site; other site
56110002897	Protein of unknown function (DUF433); Region: DUF433; cl01030
56110002898	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110002899	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110002900	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110002901	ligand binding site [chemical binding]; other site
56110002902	flexible hinge region; other site
56110002903	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
56110002904	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110002905	CHASE2 domain; Region: CHASE2; pfam05226
56110002906	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110002907	cyclase homology domain; Region: CHD; cd07302
56110002908	nucleotidyl binding site; other site
56110002909	metal binding site [ion binding]; metal-binding site
56110002910	dimer interface [polypeptide binding]; other site
56110002911	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110002912	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
56110002913	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
56110002914	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313
56110002915	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
56110002916	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
56110002917	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
56110002918	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110002919	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110002920	ATP binding site [chemical binding]; other site
56110002921	Mg2+ binding site [ion binding]; other site
56110002922	G-X-G motif; other site
56110002923	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110002924	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110002925	active site
56110002926	phosphorylation site [posttranslational modification]
56110002927	intermolecular recognition site; other site
56110002928	dimerization interface [polypeptide binding]; other site
56110002929	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110002930	DNA binding residues [nucleotide binding]
56110002931	dimerization interface [polypeptide binding]; other site
56110002932	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110002933	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110002934	S-adenosylmethionine binding site [chemical binding]; other site
56110002935	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110002936	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110002937	S-adenosylmethionine binding site [chemical binding]; other site
56110002938	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110002939	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110002940	S-adenosylmethionine binding site [chemical binding]; other site
56110002941	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
56110002942	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
56110002943	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110002944	Walker A motif; other site
56110002945	ATP binding site [chemical binding]; other site
56110002946	Walker B motif; other site
56110002947	arginine finger; other site
56110002948	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
56110002949	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
56110002950	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
56110002951	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
56110002952	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110002953	nucleophilic elbow; other site
56110002954	catalytic triad; other site
56110002955	Protein of unknown function (DUF1643); Region: DUF1643; pfam07799
56110002956	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
56110002957	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541
56110002958	putative metal binding site [ion binding]; other site
56110002959	thymidylate synthase; Provisional; Region: thyA; PRK00956
56110002960	Domain of unknown function (DUF955); Region: DUF955; pfam06114
56110002961	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110002962	non-specific DNA binding site [nucleotide binding]; other site
56110002963	salt bridge; other site
56110002964	sequence-specific DNA binding site [nucleotide binding]; other site
56110002965	XisI protein; Region: XisI; pfam08869
56110002966	XisH protein; Region: XisH; pfam08814
56110002967	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002968	binding surface
56110002969	TPR motif; other site
56110002970	TPR repeat; Region: TPR_11; pfam13414
56110002971	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002972	binding surface
56110002973	TPR motif; other site
56110002974	TPR repeat; Region: TPR_11; pfam13414
56110002975	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002976	binding surface
56110002977	TPR motif; other site
56110002978	TPR repeat; Region: TPR_11; pfam13414
56110002979	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002980	binding surface
56110002981	TPR motif; other site
56110002982	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110002983	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002984	binding surface
56110002985	TPR motif; other site
56110002986	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002987	binding surface
56110002988	TPR motif; other site
56110002989	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110002990	binding surface
56110002991	TPR motif; other site
56110002992	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002993	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002994	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002995	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110002996	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002997	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002998	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110002999	NPCBM-associated, NEW3 domain of alpha-galactosidase; Region: NPCBM_assoc; pfam10633
56110003000	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110003001	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110003002	structural tetrad; other site
56110003003	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110003004	Cache domain; Region: Cache_1; pfam02743
56110003005	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110003006	dimerization interface [polypeptide binding]; other site
56110003007	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110003008	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110003009	ligand binding site [chemical binding]; other site
56110003010	flexible hinge region; other site
56110003011	phage tail protein domain; Region: tail_TIGR02242
56110003012	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
56110003013	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
56110003014	Phage protein D [General function prediction only]; Region: COG3500
56110003015	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
56110003016	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313
56110003017	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110003018	active site
56110003019	substrate binding site [chemical binding]; other site
56110003020	ATP binding site [chemical binding]; other site
56110003021	activation loop (A-loop); other site
56110003022	PBP superfamily domain; Region: PBP_like_2; pfam12849
56110003023	Nitrogen fixation protein of unknown function; Region: Nif11; pfam07862
56110003024	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110003025	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003026	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
56110003027	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
56110003028	Zn2+ binding site [ion binding]; other site
56110003029	Mg2+ binding site [ion binding]; other site
56110003030	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
56110003031	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
56110003032	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110003033	dimer interface [polypeptide binding]; other site
56110003034	conserved gate region; other site
56110003035	putative PBP binding loops; other site
56110003036	ABC-ATPase subunit interface; other site
56110003037	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
56110003038	HsdM N-terminal domain; Region: HsdM_N; pfam12161
56110003039	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110003040	S-adenosylmethionine binding site [chemical binding]; other site
56110003041	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
56110003042	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
56110003043	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
56110003044	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110003045	AAA domain; Region: AAA_21; pfam13304
56110003046	Walker A/P-loop; other site
56110003047	ATP binding site [chemical binding]; other site
56110003048	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110003049	ABC transporter signature motif; other site
56110003050	Walker B; other site
56110003051	D-loop; other site
56110003052	H-loop/switch region; other site
56110003053	TIGR02646 family protein; Region: TIGR02646
56110003054	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
56110003055	DEAD-like helicases superfamily; Region: DEXDc; smart00487
56110003056	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
56110003057	ATP binding site [chemical binding]; other site
56110003058	putative Mg++ binding site [ion binding]; other site
56110003059	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
56110003060	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
56110003061	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
56110003062	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
56110003063	NADP binding site [chemical binding]; other site
56110003064	active site
56110003065	putative substrate binding site [chemical binding]; other site
56110003066	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
56110003067	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
56110003068	NADP-binding site; other site
56110003069	homotetramer interface [polypeptide binding]; other site
56110003070	homodimer interface [polypeptide binding]; other site
56110003071	active site
56110003072	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cl17442
56110003073	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
56110003074	substrate binding site [chemical binding]; other site
56110003075	Bacterial sugar transferase; Region: Bac_transf; pfam02397
56110003076	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
56110003077	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110003078	putative ADP-binding pocket [chemical binding]; other site
56110003079	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FcbT1; COG4663
56110003080	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
56110003081	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
56110003082	EamA-like transporter family; Region: EamA; cl17759
56110003083	EamA-like transporter family; Region: EamA; cl17759
56110003084	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110003085	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003086	active site
56110003087	phosphorylation site [posttranslational modification]
56110003088	intermolecular recognition site; other site
56110003089	dimerization interface [polypeptide binding]; other site
56110003090	argininosuccinate synthase; Provisional; Region: PRK13820
56110003091	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
56110003092	ANP binding site [chemical binding]; other site
56110003093	Substrate Binding Site II [chemical binding]; other site
56110003094	Substrate Binding Site I [chemical binding]; other site
56110003095	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
56110003096	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110003097	anti sigma factor interaction site; other site
56110003098	regulatory phosphorylation site [posttranslational modification]; other site
56110003099	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
56110003100	RNA polymerase sigma factor SigF; Reviewed; Region: PRK07408
56110003101	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110003102	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
56110003103	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110003104	DNA binding residues [nucleotide binding]
56110003105	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110003106	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003107	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003108	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110003109	non-specific DNA binding site [nucleotide binding]; other site
56110003110	salt bridge; other site
56110003111	sequence-specific DNA binding site [nucleotide binding]; other site
56110003112	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
56110003113	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
56110003114	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
56110003115	ABC transporter; Region: ABC_tran_2; pfam12848
56110003116	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
56110003117	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
56110003118	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
56110003119	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
56110003120	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
56110003121	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
56110003122	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
56110003123	Probable Catalytic site; other site
56110003124	metal-binding site
56110003125	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
56110003126	rRNA interaction site [nucleotide binding]; other site
56110003127	S8 interaction site; other site
56110003128	putative laminin-1 binding site; other site
56110003129	elongation factor Ts; Reviewed; Region: tsf; PRK12332
56110003130	UBA/TS-N domain; Region: UBA; pfam00627
56110003131	Elongation factor TS; Region: EF_TS; pfam00889
56110003132	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
56110003133	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
56110003134	generic binding surface II; other site
56110003135	ssDNA binding site; other site
56110003136	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110003137	putative Mg++ binding site [ion binding]; other site
56110003138	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110003139	nucleotide binding region [chemical binding]; other site
56110003140	ATP-binding site [chemical binding]; other site
56110003141	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003142	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003143	TPR motif; other site
56110003144	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003145	binding surface
56110003146	AAA ATPase domain; Region: AAA_16; pfam13191
56110003147	AAA domain; Region: AAA_22; pfam13401
56110003148	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110003149	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110003150	structural tetrad; other site
56110003151	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110003152	structural tetrad; other site
56110003153	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110003154	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
56110003155	CpeS-like protein; Region: CpeS; pfam09367
56110003156	Phycobilisome degradation protein nblA; Region: NblA; pfam04485
56110003157	biotin synthase; Region: bioB; TIGR00433
56110003158	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110003159	FeS/SAM binding site; other site
56110003160	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
56110003161	BioY family; Region: BioY; pfam02632
56110003162	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
56110003163	lipoprotein signal peptidase; Provisional; Region: PRK14787
56110003164	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110003165	phosphopeptide binding site; other site
56110003166	Transglycosylase; Region: Transgly; pfam00912
56110003167	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
56110003168	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
56110003169	Bacterial protein of unknown function (DUF937); Region: DUF937; pfam06078
56110003170	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110003171	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
56110003172	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110003173	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110003174	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003175	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003176	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003177	binding surface
56110003178	TPR motif; other site
56110003179	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003180	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110003181	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110003182	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110003183	CHASE2 domain; Region: CHASE2; pfam05226
56110003184	PAS domain; Region: PAS_9; pfam13426
56110003185	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110003186	cyclase homology domain; Region: CHD; cd07302
56110003187	nucleotidyl binding site; other site
56110003188	metal binding site [ion binding]; metal-binding site
56110003189	dimer interface [polypeptide binding]; other site
56110003190	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
56110003191	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
56110003192	G1 box; other site
56110003193	GTP/Mg2+ binding site [chemical binding]; other site
56110003194	Switch I region; other site
56110003195	G2 box; other site
56110003196	Switch II region; other site
56110003197	G3 box; other site
56110003198	G4 box; other site
56110003199	G5 box; other site
56110003200	Domain of unknown function (DUF697); Region: DUF697; pfam05128
56110003201	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003202	TPR repeat; Region: TPR_11; pfam13414
56110003203	binding surface
56110003204	TPR motif; other site
56110003205	TPR repeat; Region: TPR_11; pfam13414
56110003206	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003207	binding surface
56110003208	TPR motif; other site
56110003209	TPR repeat; Region: TPR_11; pfam13414
56110003210	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
56110003211	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
56110003212	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
56110003213	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
56110003214	Nitrogen fixation protein of unknown function; Region: Nif11; pfam07862
56110003215	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
56110003216	putative acyl-acceptor binding pocket; other site
56110003217	Helix-turn-helix domain; Region: HTH_17; cl17695
56110003218	Exoribonuclease R [Transcription]; Region: VacB; COG0557
56110003219	RNB domain; Region: RNB; pfam00773
56110003220	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
56110003221	ribosomal protein L33; Region: rpl33; CHL00104
56110003222	RDD family; Region: RDD; pfam06271
56110003223	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
56110003224	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110003225	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110003226	active site
56110003227	Protein of unknown function (DUF433); Region: DUF433; pfam04255
56110003228	HicB family; Region: HicB; pfam05534
56110003229	PIN domain; Region: PIN_3; cl17397
56110003230	Macro domain, Poa1p_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Poa1p_like; cd02901
56110003231	ADP-ribose binding site [chemical binding]; other site
56110003232	Uncharacterized conserved protein [Function unknown]; Region: COG3465
56110003233	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110003234	putative active site [active]
56110003235	Protein of unknown function (DUF4007); Region: DUF4007; pfam13182
56110003236	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110003237	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110003238	S-adenosylmethionine binding site [chemical binding]; other site
56110003239	phycobillisome linker protein; Region: apcE; CHL00091
56110003240	Phycobilisome protein; Region: Phycobilisome; cl08227
56110003241	Phycobilisome protein; Region: Phycobilisome; cl08227
56110003242	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
56110003243	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
56110003244	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
56110003245	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
56110003246	Domain of unknown function (DUF4415); Region: DUF4415; pfam14384
56110003247	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110003248	putative active site [active]
56110003249	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110003250	active site
56110003251	NTP binding site [chemical binding]; other site
56110003252	metal binding triad [ion binding]; metal-binding site
56110003253	antibiotic binding site [chemical binding]; other site
56110003254	Uncharacterized conserved protein [Function unknown]; Region: COG2361
56110003255	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110003256	NACHT domain; Region: NACHT; pfam05729
56110003257	Walker A/P-loop; other site
56110003258	ATP binding site [chemical binding]; other site
56110003259	HEAT repeats; Region: HEAT_2; pfam13646
56110003260	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
56110003261	core domain interface [polypeptide binding]; other site
56110003262	delta subunit interface [polypeptide binding]; other site
56110003263	epsilon subunit interface [polypeptide binding]; other site
56110003264	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
56110003265	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
56110003266	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
56110003267	beta subunit interaction interface [polypeptide binding]; other site
56110003268	Walker A motif; other site
56110003269	ATP binding site [chemical binding]; other site
56110003270	Walker B motif; other site
56110003271	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
56110003272	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
56110003273	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
56110003274	ATP synthase CF0 B subunit; Region: atpF; CHL00019
56110003275	F0F1 ATP synthase subunit B; Validated; Region: PRK07352
56110003276	F0F1 ATP synthase subunit B'; Validated; Region: PRK07353
56110003277	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
56110003278	ATP synthase CF0 C subunit; Region: atpH; CHL00061
56110003279	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
56110003280	ATP synthase CF0 A subunit; Region: atpI; CHL00046
56110003281	ATP synthase I chain; Region: ATP_synt_I; pfam03899
56110003282	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
56110003283	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110003284	Walker A/P-loop; other site
56110003285	ATP binding site [chemical binding]; other site
56110003286	Q-loop/lid; other site
56110003287	ABC transporter signature motif; other site
56110003288	Walker B; other site
56110003289	D-loop; other site
56110003290	H-loop/switch region; other site
56110003291	TOBE domain; Region: TOBE_2; pfam08402
56110003292	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
56110003293	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110003294	dimer interface [polypeptide binding]; other site
56110003295	conserved gate region; other site
56110003296	putative PBP binding loops; other site
56110003297	ABC-ATPase subunit interface; other site
56110003298	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110003299	dimer interface [polypeptide binding]; other site
56110003300	conserved gate region; other site
56110003301	putative PBP binding loops; other site
56110003302	ABC-ATPase subunit interface; other site
56110003303	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
56110003304	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
56110003305	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
56110003306	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
56110003307	S-layer homology domain; Region: SLH; pfam00395
56110003308	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
56110003309	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
56110003310	dimer interface [polypeptide binding]; other site
56110003311	[2Fe-2S] cluster binding site [ion binding]; other site
56110003312	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
56110003313	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
56110003314	dimerization interface [polypeptide binding]; other site
56110003315	DPS ferroxidase diiron center [ion binding]; other site
56110003316	ion pore; other site
56110003317	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
56110003318	metal binding site 2 [ion binding]; metal-binding site
56110003319	putative DNA binding helix; other site
56110003320	metal binding site 1 [ion binding]; metal-binding site
56110003321	dimer interface [polypeptide binding]; other site
56110003322	structural Zn2+ binding site [ion binding]; other site
56110003323	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
56110003324	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
56110003325	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
56110003326	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
56110003327	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
56110003328	ATP-grasp domain; Region: ATP-grasp_4; cl17255
56110003329	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
56110003330	IMP binding site; other site
56110003331	dimer interface [polypeptide binding]; other site
56110003332	interdomain contacts; other site
56110003333	partial ornithine binding site; other site
56110003334	RNA polymerase sigma factor SigD; Validated; Region: PRK07405
56110003335	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
56110003336	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110003337	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
56110003338	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110003339	DNA binding residues [nucleotide binding]
56110003340	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110003341	putative active site [active]
56110003342	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110003343	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
56110003344	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110003345	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110003346	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110003347	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003348	dimer interface [polypeptide binding]; other site
56110003349	phosphorylation site [posttranslational modification]
56110003350	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003351	ATP binding site [chemical binding]; other site
56110003352	Mg2+ binding site [ion binding]; other site
56110003353	G-X-G motif; other site
56110003354	Response regulator receiver domain; Region: Response_reg; pfam00072
56110003355	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003356	active site
56110003357	phosphorylation site [posttranslational modification]
56110003358	intermolecular recognition site; other site
56110003359	dimerization interface [polypeptide binding]; other site
56110003360	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110003361	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003362	active site
56110003363	phosphorylation site [posttranslational modification]
56110003364	intermolecular recognition site; other site
56110003365	CHASE domain; Region: CHASE; cl01369
56110003366	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003367	PAS fold; Region: PAS_3; pfam08447
56110003368	putative active site [active]
56110003369	heme pocket [chemical binding]; other site
56110003370	PAS domain S-box; Region: sensory_box; TIGR00229
56110003371	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003372	putative active site [active]
56110003373	heme pocket [chemical binding]; other site
56110003374	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110003375	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
56110003376	putative active site [active]
56110003377	heme pocket [chemical binding]; other site
56110003378	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003379	dimer interface [polypeptide binding]; other site
56110003380	phosphorylation site [posttranslational modification]
56110003381	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003382	ATP binding site [chemical binding]; other site
56110003383	Mg2+ binding site [ion binding]; other site
56110003384	G-X-G motif; other site
56110003385	chaperone protein DnaJ; Provisional; Region: PRK14299
56110003386	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110003387	HSP70 interaction site [polypeptide binding]; other site
56110003388	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
56110003389	dimer interface [polypeptide binding]; other site
56110003390	molecular chaperone DnaK; Provisional; Region: PRK13410
56110003391	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
56110003392	nucleotide binding site [chemical binding]; other site
56110003393	NEF interaction site [polypeptide binding]; other site
56110003394	SBD interface [polypeptide binding]; other site
56110003395	phenylalanyl-tRNA synthetase subunit alpha; Provisional; Region: pheS; PRK04172
56110003396	VanW like protein; Region: VanW; pfam04294
56110003397	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
56110003398	Methyltransferase domain; Region: Methyltransf_26; pfam13659
56110003399	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
56110003400	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110003401	cofactor binding site; other site
56110003402	DNA binding site [nucleotide binding]
56110003403	substrate interaction site [chemical binding]; other site
56110003404	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110003405	Response regulator receiver domain; Region: Response_reg; pfam00072
56110003406	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003407	active site
56110003408	phosphorylation site [posttranslational modification]
56110003409	intermolecular recognition site; other site
56110003410	dimerization interface [polypeptide binding]; other site
56110003411	phytoene desaturase; Region: phytoene_desat; TIGR02731
56110003412	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110003413	Elongation factor TS; Region: EF_TS; pfam00889
56110003414	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
56110003415	active site lid residues [active]
56110003416	substrate binding pocket [chemical binding]; other site
56110003417	catalytic residues [active]
56110003418	substrate-Mg2+ binding site; other site
56110003419	aspartate-rich region 1; other site
56110003420	aspartate-rich region 2; other site
56110003421	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110003422	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
56110003423	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
56110003424	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
56110003425	Tic20-like protein; Region: Tic20; pfam09685
56110003426	Tic20-like protein; Region: Tic20; pfam09685
56110003427	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110003428	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110003429	active site
56110003430	ATP binding site [chemical binding]; other site
56110003431	substrate binding site [chemical binding]; other site
56110003432	activation loop (A-loop); other site
56110003433	PQQ-like domain; Region: PQQ_2; pfam13360
56110003434	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110003435	structural tetrad; other site
56110003436	phycocyanin beta subunit; Reviewed; Region: cpcB; CHL00171
56110003437	phycocyanin, alpha subunit; Region: phycocy_alpha; TIGR01338
56110003438	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
56110003439	CpcD/allophycocyanin linker domain; Region: CpcD; pfam01383
56110003440	CpcD/allophycocyanin linker domain; Region: CpcD; pfam01383
56110003441	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
56110003442	E-Z type HEAT repeats; Region: EZ_HEAT; smart00567
56110003443	HEAT repeats; Region: HEAT_2; pfam13646
56110003444	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110003445	S-adenosylmethionine binding site [chemical binding]; other site
56110003446	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
56110003447	isocitrate dehydrogenase; Validated; Region: PRK07362
56110003448	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
56110003449	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
56110003450	Response regulator receiver domain; Region: Response_reg; pfam00072
56110003451	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003452	active site
56110003453	phosphorylation site [posttranslational modification]
56110003454	intermolecular recognition site; other site
56110003455	dimerization interface [polypeptide binding]; other site
56110003456	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110003457	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110003458	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
56110003459	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110003460	anti sigma factor interaction site; other site
56110003461	regulatory phosphorylation site [posttranslational modification]; other site
56110003462	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
56110003463	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
56110003464	dimer interface [polypeptide binding]; other site
56110003465	anticodon binding site; other site
56110003466	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
56110003467	homodimer interface [polypeptide binding]; other site
56110003468	motif 1; other site
56110003469	active site
56110003470	motif 2; other site
56110003471	GAD domain; Region: GAD; pfam02938
56110003472	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
56110003473	active site
56110003474	motif 3; other site
56110003475	PAS fold; Region: PAS_4; pfam08448
56110003476	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003477	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110003478	putative active site [active]
56110003479	heme pocket [chemical binding]; other site
56110003480	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003481	dimer interface [polypeptide binding]; other site
56110003482	phosphorylation site [posttranslational modification]
56110003483	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003484	ATP binding site [chemical binding]; other site
56110003485	Mg2+ binding site [ion binding]; other site
56110003486	G-X-G motif; other site
56110003487	shikimate kinase; Reviewed; Region: aroK; PRK00131
56110003488	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
56110003489	ADP binding site [chemical binding]; other site
56110003490	magnesium binding site [ion binding]; other site
56110003491	putative shikimate binding site; other site
56110003492	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
56110003493	feedback inhibition sensing region; other site
56110003494	homohexameric interface [polypeptide binding]; other site
56110003495	nucleotide binding site [chemical binding]; other site
56110003496	N-acetyl-L-glutamate binding site [chemical binding]; other site
56110003497	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110003498	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
56110003499	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110003500	Walker A motif; other site
56110003501	ATP binding site [chemical binding]; other site
56110003502	Walker B motif; other site
56110003503	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
56110003504	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
56110003505	G1 box; other site
56110003506	putative GEF interaction site [polypeptide binding]; other site
56110003507	GTP/Mg2+ binding site [chemical binding]; other site
56110003508	Switch I region; other site
56110003509	G2 box; other site
56110003510	G3 box; other site
56110003511	Switch II region; other site
56110003512	G4 box; other site
56110003513	G5 box; other site
56110003514	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
56110003515	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
56110003516	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003517	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110003518	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003519	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003520	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003521	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003522	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110003523	Stage II sporulation protein; Region: SpoIID; pfam08486
56110003524	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
56110003525	ribonuclease Z; Region: RNase_Z; TIGR02651
56110003526	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
56110003527	homotrimer interface [polypeptide binding]; other site
56110003528	Walker A motif; other site
56110003529	GTP binding site [chemical binding]; other site
56110003530	Walker B motif; other site
56110003531	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110003532	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110003533	active site
56110003534	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110003535	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
56110003536	putative metal binding site; other site
56110003537	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110003538	Probable transposase; Region: OrfB_IS605; pfam01385
56110003539	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110003540	Protein of unknown function (DUF1517); Region: DUF1517; pfam07466
56110003541	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
56110003542	thiS-thiF/thiG interaction site; other site
56110003543	thiamine-phosphate pyrophosphorylase; Provisional; Region: PRK02615
56110003544	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
56110003545	thiamine phosphate binding site [chemical binding]; other site
56110003546	active site
56110003547	pyrophosphate binding site [ion binding]; other site
56110003548	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
56110003549	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
56110003550	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
56110003551	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
56110003552	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
56110003553	Sm and related proteins; Region: Sm_like; cl00259
56110003554	heptamer interface [polypeptide binding]; other site
56110003555	Sm1 motif; other site
56110003556	hexamer interface [polypeptide binding]; other site
56110003557	RNA binding site [nucleotide binding]; other site
56110003558	Sm2 motif; other site
56110003559	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
56110003560	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
56110003561	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
56110003562	TrkA-N domain; Region: TrkA_N; pfam02254
56110003563	TrkA-C domain; Region: TrkA_C; pfam02080
56110003564	TrkA-C domain; Region: TrkA_C; pfam02080
56110003565	YtkA-like; Region: YtkA; pfam13115
56110003566	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110003567	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110003568	Late competence development protein ComFB; Region: ComFB; pfam10719
56110003569	Response regulator receiver domain; Region: Response_reg; pfam00072
56110003570	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003571	active site
56110003572	phosphorylation site [posttranslational modification]
56110003573	intermolecular recognition site; other site
56110003574	dimerization interface [polypeptide binding]; other site
56110003575	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110003576	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
56110003577	dimer interface [polypeptide binding]; other site
56110003578	phosphorylation site [posttranslational modification]
56110003579	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003580	ATP binding site [chemical binding]; other site
56110003581	Mg2+ binding site [ion binding]; other site
56110003582	G-X-G motif; other site
56110003583	Response regulator receiver domain; Region: Response_reg; pfam00072
56110003584	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003585	active site
56110003586	phosphorylation site [posttranslational modification]
56110003587	intermolecular recognition site; other site
56110003588	dimerization interface [polypeptide binding]; other site
56110003589	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003590	dimer interface [polypeptide binding]; other site
56110003591	phosphorylation site [posttranslational modification]
56110003592	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003593	ATP binding site [chemical binding]; other site
56110003594	Mg2+ binding site [ion binding]; other site
56110003595	G-X-G motif; other site
56110003596	FOG: CBS domain [General function prediction only]; Region: COG0517
56110003597	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110003598	FOG: CBS domain [General function prediction only]; Region: COG0517
56110003599	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with a PAS domain, a GGDEF (DiGuanylate-Cyclase (DGC) domain, and a DUF1 domain downstream. PAS domains have been found to bind ligands, and to act...; Region: CBS_pair_PAS_GGDEF_DUF1_assoc; cd04611
56110003600	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110003601	GAF domain; Region: GAF; pfam01590
56110003602	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003603	PAS fold; Region: PAS_3; pfam08447
56110003604	putative active site [active]
56110003605	heme pocket [chemical binding]; other site
56110003606	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003607	PAS domain; Region: PAS_9; pfam13426
56110003608	putative active site [active]
56110003609	heme pocket [chemical binding]; other site
56110003610	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003611	PAS fold; Region: PAS_3; pfam08447
56110003612	putative active site [active]
56110003613	heme pocket [chemical binding]; other site
56110003614	PAS fold; Region: PAS_4; pfam08448
56110003615	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003616	putative active site [active]
56110003617	heme pocket [chemical binding]; other site
56110003618	PAS fold; Region: PAS_4; pfam08448
56110003619	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003620	putative active site [active]
56110003621	heme pocket [chemical binding]; other site
56110003622	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110003623	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110003624	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003625	PAS fold; Region: PAS_3; pfam08447
56110003626	putative active site [active]
56110003627	heme pocket [chemical binding]; other site
56110003628	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110003629	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110003630	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003631	dimer interface [polypeptide binding]; other site
56110003632	phosphorylation site [posttranslational modification]
56110003633	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003634	ATP binding site [chemical binding]; other site
56110003635	Mg2+ binding site [ion binding]; other site
56110003636	G-X-G motif; other site
56110003637	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110003638	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003639	active site
56110003640	phosphorylation site [posttranslational modification]
56110003641	intermolecular recognition site; other site
56110003642	dimerization interface [polypeptide binding]; other site
56110003643	Predicted protease of the Abi (CAAX) family [General function prediction only]; Region: COG4449
56110003644	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110003645	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003646	active site
56110003647	phosphorylation site [posttranslational modification]
56110003648	intermolecular recognition site; other site
56110003649	dimerization interface [polypeptide binding]; other site
56110003650	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110003651	DNA binding residues [nucleotide binding]
56110003652	dimerization interface [polypeptide binding]; other site
56110003653	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
56110003654	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
56110003655	active site
56110003656	nucleotide binding site [chemical binding]; other site
56110003657	HIGH motif; other site
56110003658	KMSKS motif; other site
56110003659	GUN4-like; Region: GUN4; pfam05419
56110003660	Transposase domain (DUF772); Region: DUF772; pfam05598
56110003661	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110003662	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
56110003663	putative bicarbonate transporter, IctB family; Region: 2A73; TIGR00947
56110003664	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110003665	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003666	dimer interface [polypeptide binding]; other site
56110003667	phosphorylation site [posttranslational modification]
56110003668	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003669	ATP binding site [chemical binding]; other site
56110003670	Mg2+ binding site [ion binding]; other site
56110003671	G-X-G motif; other site
56110003672	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
56110003673	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
56110003674	dsRNA-specific ribonuclease [Transcription]; Region: Rnc; COG0571
56110003675	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
56110003676	dimerization interface [polypeptide binding]; other site
56110003677	active site
56110003678	metal binding site [ion binding]; metal-binding site
56110003679	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
56110003680	dsRNA binding site [nucleotide binding]; other site
56110003681	Putative transcription activator [Transcription]; Region: TenA; COG0819
56110003682	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
56110003683	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
56110003684	oligomer interface [polypeptide binding]; other site
56110003685	metal binding site [ion binding]; metal-binding site
56110003686	metal binding site [ion binding]; metal-binding site
56110003687	Cl binding site [ion binding]; other site
56110003688	aspartate ring; other site
56110003689	basic sphincter; other site
56110003690	putative hydrophobic gate; other site
56110003691	periplasmic entrance; other site
56110003692	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003693	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003694	binding surface
56110003695	TPR motif; other site
56110003696	TPR repeat; Region: TPR_11; pfam13414
56110003697	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003698	binding surface
56110003699	TPR motif; other site
56110003700	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003701	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003702	binding surface
56110003703	TPR motif; other site
56110003704	CHAT domain; Region: CHAT; pfam12770
56110003705	Growth inhibitor [Signal transduction mechanisms]; Region: MazF; COG2337
56110003706	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110003707	putative active site [active]
56110003708	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110003709	putative active site [active]
56110003710	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
56110003711	Clp amino terminal domain; Region: Clp_N; pfam02861
56110003712	Clp amino terminal domain; Region: Clp_N; pfam02861
56110003713	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110003714	Walker A motif; other site
56110003715	ATP binding site [chemical binding]; other site
56110003716	Walker B motif; other site
56110003717	arginine finger; other site
56110003718	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110003719	Walker A motif; other site
56110003720	ATP binding site [chemical binding]; other site
56110003721	Walker B motif; other site
56110003722	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
56110003723	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110003724	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110003725	structural tetrad; other site
56110003726	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110003727	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
56110003728	cofactor binding site; other site
56110003729	DNA binding site [nucleotide binding]
56110003730	substrate interaction site [chemical binding]; other site
56110003731	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110003732	Clp protease ATP binding subunit; Region: clpC; CHL00095
56110003733	Clp amino terminal domain; Region: Clp_N; pfam02861
56110003734	Clp amino terminal domain; Region: Clp_N; pfam02861
56110003735	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110003736	Walker A motif; other site
56110003737	ATP binding site [chemical binding]; other site
56110003738	Walker B motif; other site
56110003739	arginine finger; other site
56110003740	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110003741	Walker A motif; other site
56110003742	ATP binding site [chemical binding]; other site
56110003743	Walker B motif; other site
56110003744	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
56110003745	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110003746	Predicted nuclease of restriction endonuclease-like fold [General function prediction only]; Region: COG3372
56110003747	Protein of unknown function (DUF790); Region: DUF790; pfam05626
56110003748	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110003749	Coenzyme A binding pocket [chemical binding]; other site
56110003750	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
56110003751	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
56110003752	GIY-YIG motif/motif A; other site
56110003753	active site
56110003754	catalytic site [active]
56110003755	putative DNA binding site [nucleotide binding]; other site
56110003756	metal binding site [ion binding]; metal-binding site
56110003757	UvrB/uvrC motif; Region: UVR; pfam02151
56110003758	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
56110003759	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
56110003760	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110003761	putative active site [active]
56110003762	Double zinc ribbon; Region: DZR; pfam12773
56110003763	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110003764	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110003765	active site
56110003766	ATP binding site [chemical binding]; other site
56110003767	substrate binding site [chemical binding]; other site
56110003768	activation loop (A-loop); other site
56110003769	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110003770	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110003771	structural tetrad; other site
56110003772	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
56110003773	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110003774	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110003775	active site
56110003776	ATP binding site [chemical binding]; other site
56110003777	substrate binding site [chemical binding]; other site
56110003778	activation loop (A-loop); other site
56110003779	PQQ-like domain; Region: PQQ_2; pfam13360
56110003780	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110003781	structural tetrad; other site
56110003782	Predicted membrane protein [Function unknown]; Region: COG1808
56110003783	BON domain; Region: BON; pfam04972
56110003784	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
56110003785	Predicted membrane protein [Function unknown]; Region: COG4325
56110003786	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
56110003787	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
56110003788	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
56110003789	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
56110003790	ligand-binding site [chemical binding]; other site
56110003791	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
56110003792	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
56110003793	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110003794	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003795	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110003796	TPR motif; other site
56110003797	binding surface
56110003798	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
56110003799	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
56110003800	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110003801	dimerization interface [polypeptide binding]; other site
56110003802	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110003803	dimer interface [polypeptide binding]; other site
56110003804	putative CheW interface [polypeptide binding]; other site
56110003805	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
56110003806	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110003807	putative binding surface; other site
56110003808	active site
56110003809	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
56110003810	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003811	ATP binding site [chemical binding]; other site
56110003812	Mg2+ binding site [ion binding]; other site
56110003813	G-X-G motif; other site
56110003814	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
56110003815	Response regulator receiver domain; Region: Response_reg; pfam00072
56110003816	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003817	active site
56110003818	phosphorylation site [posttranslational modification]
56110003819	intermolecular recognition site; other site
56110003820	dimerization interface [polypeptide binding]; other site
56110003821	chemotaxis-specific methylesterase; Provisional; Region: PRK12555
56110003822	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003823	active site
56110003824	phosphorylation site [posttranslational modification]
56110003825	intermolecular recognition site; other site
56110003826	dimerization interface [polypeptide binding]; other site
56110003827	CheB methylesterase; Region: CheB_methylest; pfam01339
56110003828	Response regulator receiver domain; Region: Response_reg; pfam00072
56110003829	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003830	active site
56110003831	phosphorylation site [posttranslational modification]
56110003832	intermolecular recognition site; other site
56110003833	dimerization interface [polypeptide binding]; other site
56110003834	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003835	dimer interface [polypeptide binding]; other site
56110003836	phosphorylation site [posttranslational modification]
56110003837	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003838	ATP binding site [chemical binding]; other site
56110003839	Mg2+ binding site [ion binding]; other site
56110003840	G-X-G motif; other site
56110003841	acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK07418
56110003842	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
56110003843	PYR/PP interface [polypeptide binding]; other site
56110003844	dimer interface [polypeptide binding]; other site
56110003845	TPP binding site [chemical binding]; other site
56110003846	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
56110003847	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
56110003848	TPP-binding site [chemical binding]; other site
56110003849	dimer interface [polypeptide binding]; other site
56110003850	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
56110003851	TPR repeat; Region: TPR_11; pfam13414
56110003852	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003853	binding surface
56110003854	TPR motif; other site
56110003855	TPR repeat; Region: TPR_11; pfam13414
56110003856	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003857	binding surface
56110003858	TPR motif; other site
56110003859	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110003860	Ferredoxin [Energy production and conversion]; Region: COG1146
56110003861	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
56110003862	PAS domain; Region: PAS_9; pfam13426
56110003863	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110003864	GAF domain; Region: GAF; pfam01590
56110003865	PAS domain; Region: PAS_9; pfam13426
56110003866	PAS fold; Region: PAS_4; pfam08448
56110003867	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110003868	putative active site [active]
56110003869	heme pocket [chemical binding]; other site
56110003870	PAS fold; Region: PAS_3; pfam08447
56110003871	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
56110003872	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110003873	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110003874	dimer interface [polypeptide binding]; other site
56110003875	phosphorylation site [posttranslational modification]
56110003876	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110003877	ATP binding site [chemical binding]; other site
56110003878	Mg2+ binding site [ion binding]; other site
56110003879	G-X-G motif; other site
56110003880	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292
56110003881	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
56110003882	dimer interface [polypeptide binding]; other site
56110003883	motif 1; other site
56110003884	active site
56110003885	motif 2; other site
56110003886	motif 3; other site
56110003887	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110003888	HSP70 interaction site [polypeptide binding]; other site
56110003889	TPR repeat; Region: TPR_11; pfam13414
56110003890	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003891	binding surface
56110003892	TPR motif; other site
56110003893	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
56110003894	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
56110003895	active site
56110003896	dimerization interface [polypeptide binding]; other site
56110003897	Staphylococcal nuclease homologues; Region: SNc; smart00318
56110003898	Catalytic site; other site
56110003899	Staphylococcal nuclease homologue; Region: SNase; pfam00565
56110003900	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
56110003901	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110003902	catalytic loop [active]
56110003903	iron binding site [ion binding]; other site
56110003904	Predicted permeases [General function prediction only]; Region: RarD; COG2962
56110003905	EamA-like transporter family; Region: EamA; pfam00892
56110003906	EamA-like transporter family; Region: EamA; pfam00892
56110003907	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
56110003908	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
56110003909	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110003910	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
56110003911	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
56110003912	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
56110003913	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
56110003914	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110003915	Walker A motif; other site
56110003916	ATP binding site [chemical binding]; other site
56110003917	Walker B motif; other site
56110003918	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
56110003919	Clp protease; Region: CLP_protease; pfam00574
56110003920	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
56110003921	oligomer interface [polypeptide binding]; other site
56110003922	active site residues [active]
56110003923	trigger factor; Provisional; Region: tig; PRK01490
56110003924	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
56110003925	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
56110003926	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
56110003927	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
56110003928	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
56110003929	dihydrodipicolinate synthase; Region: dapA; TIGR00674
56110003930	dimer interface [polypeptide binding]; other site
56110003931	active site
56110003932	catalytic residue [active]
56110003933	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
56110003934	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
56110003935	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
56110003936	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
56110003937	Domain of unknown function (DUF3578); Region: DUF3578; pfam12102
56110003938	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110003939	active site
56110003940	magnesium chelatase subunit H; Provisional; Region: PRK12493
56110003941	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
56110003942	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
56110003943	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
56110003944	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
56110003945	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
56110003946	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
56110003947	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
56110003948	Ligand binding site; other site
56110003949	Putative Catalytic site; other site
56110003950	DXD motif; other site
56110003951	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
56110003952	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110003953	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110003954	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003955	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003956	TPR motif; other site
56110003957	binding surface
56110003958	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003959	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003960	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003961	TPR motif; other site
56110003962	binding surface
56110003963	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003964	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003965	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003966	binding surface
56110003967	TPR motif; other site
56110003968	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003969	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110003970	TPR motif; other site
56110003971	binding surface
56110003972	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110003973	CHAT domain; Region: CHAT; pfam12770
56110003974	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110003975	S-adenosylmethionine binding site [chemical binding]; other site
56110003976	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
56110003977	PRC-barrel domain; Region: PRC; pfam05239
56110003978	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3861
56110003979	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110003980	putative binding surface; other site
56110003981	active site
56110003982	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003983	active site
56110003984	Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]; Region: PleD; COG3706
56110003985	phosphorylation site [posttranslational modification]
56110003986	intermolecular recognition site; other site
56110003987	dimerization interface [polypeptide binding]; other site
56110003988	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110003989	active site
56110003990	phosphorylation site [posttranslational modification]
56110003991	intermolecular recognition site; other site
56110003992	dimerization interface [polypeptide binding]; other site
56110003993	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110003994	metal binding site [ion binding]; metal-binding site
56110003995	active site
56110003996	I-site; other site
56110003997	Transposase domain (DUF772); Region: DUF772; pfam05598
56110003998	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110003999	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110004000	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110004001	active site
56110004002	phosphorylation site [posttranslational modification]
56110004003	intermolecular recognition site; other site
56110004004	dimerization interface [polypeptide binding]; other site
56110004005	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110004006	DNA binding site [nucleotide binding]
56110004007	ATP synthase CF1 epsilon subunit; Region: atpE; CHL00063
56110004008	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
56110004009	gamma subunit interface [polypeptide binding]; other site
56110004010	epsilon subunit interface [polypeptide binding]; other site
56110004011	LBP interface [polypeptide binding]; other site
56110004012	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
56110004013	EamA-like transporter family; Region: EamA; pfam00892
56110004014	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
56110004015	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
56110004016	nucleotide binding pocket [chemical binding]; other site
56110004017	K-X-D-G motif; other site
56110004018	catalytic site [active]
56110004019	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
56110004020	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
56110004021	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
56110004022	Dimer interface [polypeptide binding]; other site
56110004023	BRCT sequence motif; other site
56110004024	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
56110004025	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
56110004026	Walker A/P-loop; other site
56110004027	ATP binding site [chemical binding]; other site
56110004028	Q-loop/lid; other site
56110004029	ABC transporter signature motif; other site
56110004030	Walker B; other site
56110004031	D-loop; other site
56110004032	H-loop/switch region; other site
56110004033	DevC protein; Region: devC; TIGR01185
56110004034	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
56110004035	FtsX-like permease family; Region: FtsX; pfam02687
56110004036	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II/unknown domain fusion protein; Provisional; Region: PRK09319
56110004037	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
56110004038	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
56110004039	dimerization interface [polypeptide binding]; other site
56110004040	active site
56110004041	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
56110004042	PAS domain S-box; Region: sensory_box; TIGR00229
56110004043	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004044	putative active site [active]
56110004045	heme pocket [chemical binding]; other site
56110004046	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004047	PAS fold; Region: PAS_3; pfam08447
56110004048	putative active site [active]
56110004049	heme pocket [chemical binding]; other site
56110004050	PAS fold; Region: PAS_4; pfam08448
56110004051	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004052	putative active site [active]
56110004053	heme pocket [chemical binding]; other site
56110004054	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004055	PAS domain; Region: PAS_9; pfam13426
56110004056	putative active site [active]
56110004057	heme pocket [chemical binding]; other site
56110004058	PAS domain; Region: PAS_9; pfam13426
56110004059	PAS domain S-box; Region: sensory_box; TIGR00229
56110004060	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004061	putative active site [active]
56110004062	heme pocket [chemical binding]; other site
56110004063	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110004064	dimer interface [polypeptide binding]; other site
56110004065	phosphorylation site [posttranslational modification]
56110004066	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004067	ATP binding site [chemical binding]; other site
56110004068	Mg2+ binding site [ion binding]; other site
56110004069	G-X-G motif; other site
56110004070	Response regulator receiver domain; Region: Response_reg; pfam00072
56110004071	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110004072	active site
56110004073	phosphorylation site [posttranslational modification]
56110004074	intermolecular recognition site; other site
56110004075	dimerization interface [polypeptide binding]; other site
56110004076	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110004077	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110004078	active site
56110004079	phosphorylation site [posttranslational modification]
56110004080	intermolecular recognition site; other site
56110004081	dimerization interface [polypeptide binding]; other site
56110004082	PAS fold; Region: PAS_4; pfam08448
56110004083	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004084	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110004085	putative active site [active]
56110004086	heme pocket [chemical binding]; other site
56110004087	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110004088	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004089	putative active site [active]
56110004090	heme pocket [chemical binding]; other site
56110004091	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110004092	dimer interface [polypeptide binding]; other site
56110004093	phosphorylation site [posttranslational modification]
56110004094	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004095	ATP binding site [chemical binding]; other site
56110004096	Mg2+ binding site [ion binding]; other site
56110004097	G-X-G motif; other site
56110004098	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110004099	Response regulator receiver domain; Region: Response_reg; pfam00072
56110004100	active site
56110004101	phosphorylation site [posttranslational modification]
56110004102	intermolecular recognition site; other site
56110004103	dimerization interface [polypeptide binding]; other site
56110004104	TPR repeat; Region: TPR_11; pfam13414
56110004105	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004106	binding surface
56110004107	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110004108	TPR motif; other site
56110004109	Methyltransferase domain; Region: Methyltransf_24; pfam13578
56110004110	aspartate aminotransferase; Provisional; Region: PRK05764
56110004111	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110004112	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110004113	homodimer interface [polypeptide binding]; other site
56110004114	catalytic residue [active]
56110004115	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
56110004116	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
56110004117	putative active site; other site
56110004118	catalytic residue [active]
56110004119	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
56110004120	30S subunit binding site; other site
56110004121	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
56110004122	DNA-binding site [nucleotide binding]; DNA binding site
56110004123	RNA-binding motif; other site
56110004124	Bacterial SH3 domain; Region: SH3_3; cl17532
56110004125	Bacterial SH3 domain; Region: SH3_3; pfam08239
56110004126	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
56110004127	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
56110004128	putative NAD(P) binding site [chemical binding]; other site
56110004129	putative active site [active]
56110004130	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110004131	putative active site [active]
56110004132	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110004133	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110004134	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110004135	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004136	structural tetrad; other site
56110004137	PQQ-like domain; Region: PQQ_2; pfam13360
56110004138	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110004139	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110004140	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110004141	structural tetrad; other site
56110004142	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110004143	TPR repeat; Region: TPR_11; pfam13414
56110004144	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004145	TPR motif; other site
56110004146	binding surface
56110004147	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110004148	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004149	binding surface
56110004150	TPR motif; other site
56110004151	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110004152	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004153	TPR motif; other site
56110004154	TPR repeat; Region: TPR_11; pfam13414
56110004155	binding surface
56110004156	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110004157	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004158	binding surface
56110004159	TPR motif; other site
56110004160	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004161	structural tetrad; other site
56110004162	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
56110004163	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110004164	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110004165	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110004166	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110004167	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110004168	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004169	binding surface
56110004170	TPR motif; other site
56110004171	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004172	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004173	binding surface
56110004174	TPR motif; other site
56110004175	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004176	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004177	binding surface
56110004178	TPR motif; other site
56110004179	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004180	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004181	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004182	binding surface
56110004183	TPR motif; other site
56110004184	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004185	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004186	TPR motif; other site
56110004187	binding surface
56110004188	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004189	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004190	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004191	binding surface
56110004192	TPR motif; other site
56110004193	CHAT domain; Region: CHAT; cl17868
56110004194	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110004195	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
56110004196	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004197	TPR motif; other site
56110004198	binding surface
56110004199	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
56110004200	substrate binding site; other site
56110004201	dimer interface; other site
56110004202	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
56110004203	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
56110004204	putative active site [active]
56110004205	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
56110004206	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110004207	active site
56110004208	motif I; other site
56110004209	motif II; other site
56110004210	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
56110004211	Bacterial sugar transferase; Region: Bac_transf; pfam02397
56110004212	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
56110004213	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
56110004214	Protein of unknown function (DUF565); Region: DUF565; pfam04483
56110004215	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
56110004216	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
56110004217	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110004218	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110004219	dimer interface [polypeptide binding]; other site
56110004220	phosphorylation site [posttranslational modification]
56110004221	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004222	ATP binding site [chemical binding]; other site
56110004223	Mg2+ binding site [ion binding]; other site
56110004224	G-X-G motif; other site
56110004225	Response regulator receiver domain; Region: Response_reg; pfam00072
56110004226	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110004227	active site
56110004228	phosphorylation site [posttranslational modification]
56110004229	intermolecular recognition site; other site
56110004230	dimerization interface [polypeptide binding]; other site
56110004231	KaiA domain; Region: KaiA; pfam07688
56110004232	KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part...; Region: KaiB_like; cd02978
56110004233	tetramer interface [polypeptide binding]; other site
56110004234	dimer interface [polypeptide binding]; other site
56110004235	circadian clock protein KaiC; Region: circ_KaiC; TIGR02655
56110004236	KaiC is a circadian clock protein primarily found in cyanobacteria KaiC is a RecA-like ATPase, having both Walker A and Walker B motifs. A related protein is found in archaea; Region: KaiC; cd01124
56110004237	Walker A motif; other site
56110004238	ATP binding site [chemical binding]; other site
56110004239	Walker B motif; other site
56110004240	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110004241	ATP binding site [chemical binding]; other site
56110004242	Walker B motif; other site
56110004243	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110004244	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110004245	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110004246	Protein of unknown function (DUF938); Region: DUF938; pfam06080
56110004247	Rieske non-heme iron oxygenase (RO) family, Pheophorbide a oxygenase (PaO) subfamily, N-terminal Rieske domain of the oxygenase alpha subunit; composed of the oxygenase alpha subunits of a small subfamily of enzymes found in plants as well as oxygenic...; Region: Rieske_RO_Alpha_PaO; cd03480
56110004248	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
56110004249	Pheophorbide a oxygenase; Region: PaO; pfam08417
56110004250	NB-ARC domain; Region: NB-ARC; pfam00931
56110004251	WD domain, G-beta repeat; Region: WD40; pfam00400
56110004252	WD40 repeats; Region: WD40; smart00320
56110004253	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110004254	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004255	structural tetrad; other site
56110004256	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004257	structural tetrad; other site
56110004258	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
56110004259	DNA methylase; Region: N6_N4_Mtase; pfam01555
56110004260	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004261	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110004262	putative active site [active]
56110004263	heme pocket [chemical binding]; other site
56110004264	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004265	putative active site [active]
56110004266	heme pocket [chemical binding]; other site
56110004267	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004268	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110004269	putative active site [active]
56110004270	heme pocket [chemical binding]; other site
56110004271	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004272	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110004273	putative active site [active]
56110004274	heme pocket [chemical binding]; other site
56110004275	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004276	putative active site [active]
56110004277	heme pocket [chemical binding]; other site
56110004278	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004279	PAS fold; Region: PAS_3; pfam08447
56110004280	putative active site [active]
56110004281	heme pocket [chemical binding]; other site
56110004282	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004283	PAS fold; Region: PAS_4; pfam08448
56110004284	putative active site [active]
56110004285	heme pocket [chemical binding]; other site
56110004286	PAS domain S-box; Region: sensory_box; TIGR00229
56110004287	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110004288	putative active site [active]
56110004289	heme pocket [chemical binding]; other site
56110004290	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110004291	GAF domain; Region: GAF; pfam01590
56110004292	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110004293	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110004294	dimer interface [polypeptide binding]; other site
56110004295	phosphorylation site [posttranslational modification]
56110004296	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004297	ATP binding site [chemical binding]; other site
56110004298	Mg2+ binding site [ion binding]; other site
56110004299	G-X-G motif; other site
56110004300	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cl11615
56110004301	switch II binding region; other site
56110004302	Rac1 P-loop interaction site [polypeptide binding]; other site
56110004303	GTP binding residues [chemical binding]; other site
56110004304	switch I binding region; other site
56110004305	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
56110004306	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110004307	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110004308	flavoprotein, HI0933 family; Region: TIGR00275
56110004309	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
56110004310	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
56110004311	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
56110004312	NADP binding site [chemical binding]; other site
56110004313	active site
56110004314	putative substrate binding site [chemical binding]; other site
56110004315	Rubredoxin [Energy production and conversion]; Region: COG1773
56110004316	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
56110004317	iron binding site [ion binding]; other site
56110004318	ChaB; Region: ChaB; cl01887
56110004319	Domain of unknown function (DUF4112); Region: DUF4112; pfam13430
56110004320	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
56110004321	metal ion-dependent adhesion site (MIDAS); other site
56110004322	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
56110004323	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
56110004324	metal-binding site [ion binding]
56110004325	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
56110004326	Soluble P-type ATPase [General function prediction only]; Region: COG4087
56110004327	Plastocyanin domain containing protein [General function prediction only]; Region: COG4633
56110004328	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
56110004329	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
56110004330	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110004331	catalytic loop [active]
56110004332	iron binding site [ion binding]; other site
56110004333	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110004334	Ligand Binding Site [chemical binding]; other site
56110004335	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110004336	Ligand Binding Site [chemical binding]; other site
56110004337	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
56110004338	active site
56110004339	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110004340	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02755
56110004341	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
56110004342	RNA binding site [nucleotide binding]; other site
56110004343	active site
56110004344	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
56110004345	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
56110004346	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
56110004347	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110004348	Homeodomain-like domain; Region: HTH_23; pfam13384
56110004349	Winged helix-turn helix; Region: HTH_29; pfam13551
56110004350	Homeodomain-like domain; Region: HTH_32; pfam13565
56110004351	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110004352	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110004353	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
56110004354	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
56110004355	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
56110004356	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110004357	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110004358	HEAT repeats; Region: HEAT_2; pfam13646
56110004359	HEAT repeats; Region: HEAT_2; pfam13646
56110004360	HEAT repeats; Region: HEAT_2; pfam13646
56110004361	HEAT repeats; Region: HEAT_2; pfam13646
56110004362	Survival protein SurE; Region: SurE; cl00448
56110004363	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110004364	atypical (a) SDRs, subgroup 1; Region: SDR_a1; cd05265
56110004365	putative NAD(P) binding site [chemical binding]; other site
56110004366	active site
56110004367	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
56110004368	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
56110004369	Bacterial sugar transferase; Region: Bac_transf; pfam02397
56110004370	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
56110004371	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110004372	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110004373	ligand binding site [chemical binding]; other site
56110004374	flexible hinge region; other site
56110004375	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110004376	putative switch regulator; other site
56110004377	non-specific DNA interactions [nucleotide binding]; other site
56110004378	DNA binding site [nucleotide binding]
56110004379	sequence specific DNA binding site [nucleotide binding]; other site
56110004380	putative cAMP binding site [chemical binding]; other site
56110004381	Predicted membrane protein (DUF2232); Region: DUF2232; cl01728
56110004382	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
56110004383	putative dimer interface [polypeptide binding]; other site
56110004384	active site pocket [active]
56110004385	putative cataytic base [active]
56110004386	CpeS-like protein; Region: CpeS; pfam09367
56110004387	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
56110004388	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
56110004389	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
56110004390	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
56110004391	active site
56110004392	catalytic tetrad [active]
56110004393	Bifunctional nuclease; Region: DNase-RNase; pfam02577
56110004394	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
56110004395	Lumazine binding domain; Region: Lum_binding; pfam00677
56110004396	Lumazine binding domain; Region: Lum_binding; pfam00677
56110004397	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110004398	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110004399	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
56110004400	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
56110004401	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
56110004402	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
56110004403	P-loop containing region of AAA domain; Region: AAA_29; cl17516
56110004404	AAA domain; Region: AAA_21; pfam13304
56110004405	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110004406	ABC transporter signature motif; other site
56110004407	Walker B; other site
56110004408	D-loop; other site
56110004409	H-loop/switch region; other site
56110004410	TIGR02646 family protein; Region: TIGR02646
56110004411	C factor cell-cell signaling protein; Provisional; Region: PRK09009
56110004412	carbonyl reductase sniffer-like, classical (c) SDRs; Region: carb_red_sniffer_like_SDR_c; cd05325
56110004413	NADP binding site [chemical binding]; other site
56110004414	homodimer interface [polypeptide binding]; other site
56110004415	active site
56110004416	Protein of unknown function (DUF3353); Region: DUF3353; pfam11833
56110004417	Clp protease ATP binding subunit; Region: clpC; CHL00095
56110004418	Clp amino terminal domain; Region: Clp_N; pfam02861
56110004419	Clp amino terminal domain; Region: Clp_N; pfam02861
56110004420	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110004421	Walker A motif; other site
56110004422	ATP binding site [chemical binding]; other site
56110004423	Walker B motif; other site
56110004424	arginine finger; other site
56110004425	UvrB/uvrC motif; Region: UVR; pfam02151
56110004426	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110004427	Walker A motif; other site
56110004428	ATP binding site [chemical binding]; other site
56110004429	Walker B motif; other site
56110004430	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
56110004431	Bacterial OB fold (BOF) protein; Region: BOF; cl01196
56110004432	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110004433	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110004434	active site
56110004435	phosphorylation site [posttranslational modification]
56110004436	intermolecular recognition site; other site
56110004437	dimerization interface [polypeptide binding]; other site
56110004438	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110004439	DNA binding site [nucleotide binding]
56110004440	CHASE3 domain; Region: CHASE3; pfam05227
56110004441	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110004442	dimer interface [polypeptide binding]; other site
56110004443	phosphorylation site [posttranslational modification]
56110004444	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004445	ATP binding site [chemical binding]; other site
56110004446	Mg2+ binding site [ion binding]; other site
56110004447	G-X-G motif; other site
56110004448	serine hydroxymethyltransferase; Provisional; Region: PLN03226
56110004449	Cupin superfamily protein; Region: Cupin_4; pfam08007
56110004450	Cupin-like domain; Region: Cupin_8; pfam13621
56110004451	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
56110004452	generic binding surface II; other site
56110004453	generic binding surface I; other site
56110004454	chlorophyll a/b binding light-harvesting protein; Region: PS_antenn_a_b; TIGR03041
56110004455	flavodoxin FldA; Validated; Region: PRK09267
56110004456	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110004457	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
56110004458	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
56110004459	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110004460	active site
56110004461	metal binding site [ion binding]; metal-binding site
56110004462	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110004463	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
56110004464	ligand binding site [chemical binding]; other site
56110004465	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110004466	non-specific DNA interactions [nucleotide binding]; other site
56110004467	DNA binding site [nucleotide binding]
56110004468	sequence specific DNA binding site [nucleotide binding]; other site
56110004469	putative cAMP binding site [chemical binding]; other site
56110004470	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
56110004471	pyruvate kinase; Validated; Region: PRK08187
56110004472	domain interfaces; other site
56110004473	active site
56110004474	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
56110004475	Domain of unknown function (DUF389); Region: DUF389; cl00781
56110004476	Transposase; Region: DEDD_Tnp_IS110; pfam01548
56110004477	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
56110004478	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110004479	non-specific DNA binding site [nucleotide binding]; other site
56110004480	salt bridge; other site
56110004481	sequence-specific DNA binding site [nucleotide binding]; other site
56110004482	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110004483	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110004484	Zonular occludens toxin (Zot); Region: Zot; cl17485
56110004485	Replication initiation factor; Region: Rep_trans; pfam02486
56110004486	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
56110004487	Walker A/P-loop; other site
56110004488	ATP binding site [chemical binding]; other site
56110004489	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
56110004490	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
56110004491	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
56110004492	ABC transporter signature motif; other site
56110004493	Walker B; other site
56110004494	D-loop; other site
56110004495	H-loop/switch region; other site
56110004496	PRC-barrel domain; Region: PRC; pfam05239
56110004497	PRC-barrel domain; Region: PRC; pfam05239
56110004498	NADH dehydrogenase transmembrane subunit; Region: NdhL; pfam10716
56110004499	Protein of unknown function (DUF3007); Region: DUF3007; pfam11460
56110004500	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
56110004501	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
56110004502	substrate binding site [chemical binding]; other site
56110004503	active site
56110004504	catalytic residues [active]
56110004505	heterodimer interface [polypeptide binding]; other site
56110004506	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110004507	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
56110004508	protein binding site [polypeptide binding]; other site
56110004509	Protein of unknown function (DUF760); Region: DUF760; pfam05542
56110004510	Protein of unknown function (DUF3122); Region: DUF3122; pfam11320
56110004511	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110004512	FeS/SAM binding site; other site
56110004513	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110004514	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110004515	active site
56110004516	ATP binding site [chemical binding]; other site
56110004517	substrate binding site [chemical binding]; other site
56110004518	activation loop (A-loop); other site
56110004519	AAA ATPase domain; Region: AAA_16; pfam13191
56110004520	Predicted ATPase [General function prediction only]; Region: COG3899
56110004521	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110004522	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110004523	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004524	ATP binding site [chemical binding]; other site
56110004525	Mg2+ binding site [ion binding]; other site
56110004526	G-X-G motif; other site
56110004527	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
56110004528	extended (e) SDRs; Region: SDR_e; cd08946
56110004529	NAD(P) binding site [chemical binding]; other site
56110004530	active site
56110004531	substrate binding site [chemical binding]; other site
56110004532	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
56110004533	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
56110004534	substrate binding site [chemical binding]; other site
56110004535	active site
56110004536	Restriction endonuclease XhoI; Region: XhoI; pfam04555
56110004537	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110004538	non-specific DNA binding site [nucleotide binding]; other site
56110004539	salt bridge; other site
56110004540	sequence-specific DNA binding site [nucleotide binding]; other site
56110004541	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110004542	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110004543	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
56110004544	dimer interface [polypeptide binding]; other site
56110004545	catalytic triad [active]
56110004546	HEAT repeats; Region: HEAT_2; pfam13646
56110004547	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
56110004548	HEAT repeats; Region: HEAT_2; pfam13646
56110004549	protein binding surface [polypeptide binding]; other site
56110004550	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
56110004551	EamA-like transporter family; Region: EamA; pfam00892
56110004552	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
56110004553	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
56110004554	tandem repeat interface [polypeptide binding]; other site
56110004555	oligomer interface [polypeptide binding]; other site
56110004556	active site residues [active]
56110004557	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
56110004558	homotrimer interaction site [polypeptide binding]; other site
56110004559	active site
56110004560	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
56110004561	Beta-carotene hydroxylase (CrtR), the carotenoid zeaxanthin biosynthetic enzyme catalyzes the addition of hydroxyl groups to the beta-ionone rings of beta-carotene to form zeaxanthin and is found in bacteria and red algae. Carotenoids are important...; Region: CrtR_beta-carotene-hydroxylase; cd03514
56110004562	putative di-iron ligands [ion binding]; other site
56110004563	pyruvate kinase; Provisional; Region: PRK06354
56110004564	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
56110004565	domain interfaces; other site
56110004566	active site
56110004567	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
56110004568	Predicted acyl esterases [General function prediction only]; Region: COG2936
56110004569	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
56110004570	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
56110004571	Permeases of the major facilitator superfamily [General function prediction only]; Region: COG2270
56110004572	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
56110004573	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
56110004574	[2Fe-2S] cluster binding site [ion binding]; other site
56110004575	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
56110004576	hydrophobic ligand binding site; other site
56110004577	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
56110004578	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
56110004579	S-layer homology domain; Region: SLH; pfam00395
56110004580	S-layer homology domain; Region: SLH; pfam00395
56110004581	S-layer homology domain; Region: SLH; pfam00395
56110004582	Domain of unknown function (DUF1802); Region: DUF1802; pfam08819
56110004583	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
56110004584	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
56110004585	active site
56110004586	catalytic tetrad [active]
56110004587	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110004588	NACHT domain; Region: NACHT; pfam05729
56110004589	Walker A motif; other site
56110004590	ATP binding site [chemical binding]; other site
56110004591	Walker B motif; other site
56110004592	HEAT repeats; Region: HEAT_2; pfam13646
56110004593	HEAT repeats; Region: HEAT_2; pfam13646
56110004594	HEAT repeats; Region: HEAT_2; pfam13646
56110004595	HEAT repeats; Region: HEAT_2; pfam13646
56110004596	HEAT repeats; Region: HEAT_2; pfam13646
56110004597	HEAT repeats; Region: HEAT_2; pfam13646
56110004598	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
56110004599	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110004600	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110004601	active site
56110004602	Sucrose synthase; Region: Sucrose_synth; pfam00862
56110004603	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110004604	putative active site [active]
56110004605	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
56110004606	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
56110004607	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110004608	sequence-specific DNA binding site [nucleotide binding]; other site
56110004609	salt bridge; other site
56110004610	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110004611	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110004612	active site
56110004613	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
56110004614	active site
56110004615	oligomerization interface [polypeptide binding]; other site
56110004616	metal binding site [ion binding]; metal-binding site
56110004617	Predicted metal-dependent membrane protease [General function prediction only]; Region: COG1266
56110004618	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
56110004619	catalytic core [active]
56110004620	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
56110004621	catalytic core [active]
56110004622	dihydroorotase; Provisional; Region: PRK07369
56110004623	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
56110004624	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
56110004625	active site
56110004626	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
56110004627	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110004628	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
56110004629	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
56110004630	active site
56110004631	Beta-propeller repeat; Region: SBBP; pfam06739
56110004632	Beta-propeller repeat; Region: SBBP; pfam06739
56110004633	Beta-propeller repeat; Region: SBBP; pfam06739
56110004634	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
56110004635	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110004636	type 2 lantibiotic, mersacidin/lichenicidin family; Region: lanti_MRSA_kill; TIGR03898
56110004637	Transposase domain (DUF772); Region: DUF772; pfam05598
56110004638	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110004639	type 2 lantibiotic biosynthesis protein LanM; Region: lanti_2_LanM; TIGR03897
56110004640	LanM-like proteins. LanM is a bifunctional enzyme, involved in the synthesis of class II lantibiotics. It is responsible for both the dehydration and the cyclization of the precursor-peptide during lantibiotic synthesis. The C-terminal domain shows...; Region: LanM-like; cd04792
56110004641	active site
56110004642	zinc binding site [ion binding]; other site
56110004643	NAD(P)H-quinone oxidoreductase subunit 2; Provisional; Region: PRK02504
56110004644	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110004645	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
56110004646	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
56110004647	active site
56110004648	interdomain interaction site; other site
56110004649	putative metal-binding site [ion binding]; other site
56110004650	nucleotide binding site [chemical binding]; other site
56110004651	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
56110004652	domain I; other site
56110004653	DNA binding groove [nucleotide binding]
56110004654	phosphate binding site [ion binding]; other site
56110004655	domain II; other site
56110004656	domain III; other site
56110004657	nucleotide binding site [chemical binding]; other site
56110004658	catalytic site [active]
56110004659	domain IV; other site
56110004660	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
56110004661	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
56110004662	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
56110004663	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
56110004664	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110004665	putative active site [active]
56110004666	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110004667	putative active site [active]
56110004668	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110004669	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110004670	active site
56110004671	ATP binding site [chemical binding]; other site
56110004672	substrate binding site [chemical binding]; other site
56110004673	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110004674	substrate binding site [chemical binding]; other site
56110004675	activation loop (A-loop); other site
56110004676	activation loop (A-loop); other site
56110004677	AAA ATPase domain; Region: AAA_16; pfam13191
56110004678	Predicted ATPase [General function prediction only]; Region: COG3899
56110004679	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110004680	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110004681	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110004682	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
56110004683	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004684	ATP binding site [chemical binding]; other site
56110004685	Mg2+ binding site [ion binding]; other site
56110004686	G-X-G motif; other site
56110004687	MASE1; Region: MASE1; pfam05231
56110004688	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110004689	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
56110004690	dimer interface [polypeptide binding]; other site
56110004691	phosphorylation site [posttranslational modification]
56110004692	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110004693	ATP binding site [chemical binding]; other site
56110004694	Mg2+ binding site [ion binding]; other site
56110004695	G-X-G motif; other site
56110004696	cell division protein MukB; Provisional; Region: mukB; PRK04863
56110004697	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
56110004698	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
56110004699	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
56110004700	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
56110004701	hexamer interface [polypeptide binding]; other site
56110004702	ligand binding site [chemical binding]; other site
56110004703	putative active site [active]
56110004704	NAD(P) binding site [chemical binding]; other site
56110004705	light-harvesting-like protein 3; Provisional; Region: PLN00014
56110004706	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
56110004707	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
56110004708	DNA binding residues [nucleotide binding]
56110004709	dimer interface [polypeptide binding]; other site
56110004710	metal binding site [ion binding]; metal-binding site
56110004711	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004712	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110004713	structural tetrad; other site
56110004714	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
56110004715	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
56110004716	classical (c) SDRs; Region: SDR_c; cd05233
56110004717	NAD(P) binding site [chemical binding]; other site
56110004718	active site
56110004719	Domain of unknown function (DUF4212); Region: DUF4212; pfam13937
56110004720	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
56110004721	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
56110004722	Na binding site [ion binding]; other site
56110004723	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110004724	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004725	structural tetrad; other site
56110004726	Repair protein; Region: Repair_PSII; pfam04536
56110004727	Domain of unknown function (DUF1823); Region: DUF1823; pfam08853
56110004728	AAA ATPase domain; Region: AAA_16; pfam13191
56110004729	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110004730	WD domain, G-beta repeat; Region: WD40; pfam00400
56110004731	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004732	structural tetrad; other site
56110004733	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110004734	structural tetrad; other site
56110004735	Archaeal ATPase; Region: Arch_ATPase; pfam01637
56110004736	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110004737	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110004738	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
56110004739	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
56110004740	cell division protein FtsZ; Validated; Region: PRK09330
56110004741	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
56110004742	nucleotide binding site [chemical binding]; other site
56110004743	SulA interaction site; other site
56110004744	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
56110004745	dimer interface [polypeptide binding]; other site
56110004746	substrate binding site [chemical binding]; other site
56110004747	ATP binding site [chemical binding]; other site
56110004748	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110004749	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
56110004750	acyl-activating enzyme (AAE) consensus motif; other site
56110004751	AMP binding site [chemical binding]; other site
56110004752	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110004753	Acyltransferase family; Region: Acyl_transf_3; pfam01757
56110004754	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
56110004755	marine proteobacterial sortase target protein; Region: marine_srt_targ; TIGR03788
56110004756	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
56110004757	metal ion-dependent adhesion site (MIDAS); other site
56110004758	signal recognition particle protein; Provisional; Region: PRK10867
56110004759	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
56110004760	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
56110004761	GTP binding site [chemical binding]; other site
56110004762	Signal peptide binding domain; Region: SRP_SPB; pfam02978
56110004763	ribosomal protein S16; Region: rps16; CHL00005
56110004764	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
56110004765	KH domain; Region: KH_4; pfam13083
56110004766	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
56110004767	PhoH-like protein; Region: PhoH; pfam02562
56110004768	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
56110004769	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110004770	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
56110004771	Walker A/P-loop; other site
56110004772	ATP binding site [chemical binding]; other site
56110004773	Q-loop/lid; other site
56110004774	ABC transporter signature motif; other site
56110004775	Walker B; other site
56110004776	D-loop; other site
56110004777	H-loop/switch region; other site
56110004778	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
56110004779	Cytochrome c; Region: Cytochrom_C; pfam00034
56110004780	Cytochrome B6-F complex subunit 5; Region: PetG; cl03637
56110004781	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
56110004782	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110004783	S-adenosylmethionine binding site [chemical binding]; other site
56110004784	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110004785	putative active site [active]
56110004786	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110004787	active site
56110004788	NTP binding site [chemical binding]; other site
56110004789	metal binding triad [ion binding]; metal-binding site
56110004790	antibiotic binding site [chemical binding]; other site
56110004791	Uncharacterized conserved protein [Function unknown]; Region: COG2361
56110004792	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
56110004793	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
56110004794	Cytochrome P450; Region: p450; cl12078
56110004795	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
56110004796	TMAO/DMSO reductase; Reviewed; Region: PRK05363
56110004797	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
56110004798	Moco binding site; other site
56110004799	metal coordination site [ion binding]; other site
56110004800	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
56110004801	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
56110004802	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
56110004803	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
56110004804	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
56110004805	hinge; other site
56110004806	active site
56110004807	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
56110004808	Putative addiction module component; Region: Unstab_antitox; cl09921
56110004809	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
56110004810	Uncharacterized conserved protein [Function unknown]; Region: COG0062
56110004811	putative carbohydrate kinase; Provisional; Region: PRK10565
56110004812	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
56110004813	putative substrate binding site [chemical binding]; other site
56110004814	putative ATP binding site [chemical binding]; other site
56110004815	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
56110004816	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
56110004817	sulfate adenylyltransferase; Reviewed; Region: sat; PRK04149
56110004818	ATP-sulfurylase; Region: ATPS; cd00517
56110004819	active site
56110004820	HXXH motif; other site
56110004821	flexible loop; other site
56110004822	Caspase domain; Region: Peptidase_C14; pfam00656
56110004823	Domain of unknown function (DUF4384); Region: DUF4384; pfam14326
56110004824	4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263
56110004825	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
56110004826	dimer interface [polypeptide binding]; other site
56110004827	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
56110004828	active site
56110004829	Fe binding site [ion binding]; other site
56110004830	LabA_like proteins; Region: LabA_like; cd06167
56110004831	putative metal binding site [ion binding]; other site
56110004832	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
56110004833	GAF domain; Region: GAF; cl17456
56110004834	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
56110004835	Chain length determinant protein; Region: Wzz; cl15801
56110004836	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
56110004837	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
56110004838	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
56110004839	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
56110004840	SLBB domain; Region: SLBB; pfam10531
56110004841	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
56110004842	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
56110004843	SLBB domain; Region: SLBB; pfam10531
56110004844	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
56110004845	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
56110004846	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
56110004847	NAD(P) binding site [chemical binding]; other site
56110004848	homodimer interface [polypeptide binding]; other site
56110004849	substrate binding site [chemical binding]; other site
56110004850	active site
56110004851	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110004852	putative active site [active]
56110004853	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110004854	active site
56110004855	metal binding triad [ion binding]; metal-binding site
56110004856	antibiotic binding site [chemical binding]; other site
56110004857	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110004858	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
56110004859	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
56110004860	Mg++ binding site [ion binding]; other site
56110004861	putative catalytic motif [active]
56110004862	putative substrate binding site [chemical binding]; other site
56110004863	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110004864	active site
56110004865	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110004866	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
56110004867	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
56110004868	Mg++ binding site [ion binding]; other site
56110004869	putative catalytic motif [active]
56110004870	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
56110004871	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110004872	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110004873	S-adenosylmethionine binding site [chemical binding]; other site
56110004874	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110004875	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110004876	NAD(P) binding site [chemical binding]; other site
56110004877	active site
56110004878	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110004879	ExoA is involved in the biosynthesis of succinoglycan; Region: Succinoglycan_BP_ExoA; cd02525
56110004880	Ligand binding site; other site
56110004881	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110004882	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110004883	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
56110004884	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
56110004885	type 2 lantibiotic biosynthesis protein LanM; Region: lanti_2_LanM; TIGR03897
56110004886	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110004887	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110004888	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110004889	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
56110004890	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110004891	putative ADP-binding pocket [chemical binding]; other site
56110004892	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
56110004893	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110004894	S-adenosylmethionine binding site [chemical binding]; other site
56110004895	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110004896	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110004897	S-adenosylmethionine binding site [chemical binding]; other site
56110004898	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
56110004899	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
56110004900	trimer interface [polypeptide binding]; other site
56110004901	active site
56110004902	substrate binding site [chemical binding]; other site
56110004903	CoA binding site [chemical binding]; other site
56110004904	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
56110004905	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
56110004906	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
56110004907	inhibitor-cofactor binding pocket; inhibition site
56110004908	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110004909	catalytic residue [active]
56110004910	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110004911	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
56110004912	Domain of unknown function (DUF3368); Region: DUF3368; pfam11848
56110004913	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110004914	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
56110004915	putative trimer interface [polypeptide binding]; other site
56110004916	Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132
56110004917	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
56110004918	putative CoA binding site [chemical binding]; other site
56110004919	putative trimer interface [polypeptide binding]; other site
56110004920	putative active site [active]
56110004921	putative substrate binding site [chemical binding]; other site
56110004922	putative CoA binding site [chemical binding]; other site
56110004923	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
56110004924	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
56110004925	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
56110004926	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110004927	Transposase domain (DUF772); Region: DUF772; pfam05598
56110004928	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
56110004929	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110004930	putative active site [active]
56110004931	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110004932	Homeodomain-like domain; Region: HTH_23; pfam13384
56110004933	Winged helix-turn helix; Region: HTH_29; pfam13551
56110004934	Winged helix-turn helix; Region: HTH_33; pfam13592
56110004935	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110004936	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110004937	TPR repeat; Region: TPR_11; pfam13414
56110004938	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004939	binding surface
56110004940	TPR motif; other site
56110004941	Domain of unknown function (DUF4344); Region: DUF4344; pfam14247
56110004942	Domain of unknown function (DUF4344); Region: DUF4344; pfam14247
56110004943	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110004944	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110004945	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110004946	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110004947	NB-ARC domain; Region: NB-ARC; pfam00931
56110004948	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110004949	binding surface
56110004950	TPR motif; other site
56110004951	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110004952	Uncharacterized conserved protein [Function unknown]; Region: COG4278
56110004953	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110004954	CHAT domain; Region: CHAT; cl17868
56110004955	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110004956	Coenzyme A binding pocket [chemical binding]; other site
56110004957	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110004958	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110004959	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110004960	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
56110004961	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
56110004962	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110004963	active site
56110004964	NTP binding site [chemical binding]; other site
56110004965	metal binding triad [ion binding]; metal-binding site
56110004966	antibiotic binding site [chemical binding]; other site
56110004967	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110004968	putative active site [active]
56110004969	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
56110004970	L-iditol 2-dehydrogenase; Region: iditol_2_DH_like; cd08235
56110004971	putative NAD(P) binding site [chemical binding]; other site
56110004972	catalytic Zn binding site [ion binding]; other site
56110004973	Protein of unknown function (DUF2281); Region: DUF2281; cl02355
56110004974	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
56110004975	putative active site [active]
56110004976	Protein of unknown function (DUF2281); Region: DUF2281; cl02355
56110004977	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
56110004978	heterocyst differentiation control protein; Reviewed; Region: hetR; PRK13245
56110004979	sulfate transport protein; Provisional; Region: cysT; CHL00187
56110004980	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110004981	dimer interface [polypeptide binding]; other site
56110004982	conserved gate region; other site
56110004983	putative PBP binding loops; other site
56110004984	ABC-ATPase subunit interface; other site
56110004985	sulfate transport protein; Provisional; Region: cysT; CHL00187
56110004986	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110004987	dimer interface [polypeptide binding]; other site
56110004988	conserved gate region; other site
56110004989	putative PBP binding loops; other site
56110004990	ABC-ATPase subunit interface; other site
56110004991	ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118
56110004992	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
56110004993	Walker A/P-loop; other site
56110004994	ATP binding site [chemical binding]; other site
56110004995	Q-loop/lid; other site
56110004996	ABC transporter signature motif; other site
56110004997	Walker B; other site
56110004998	D-loop; other site
56110004999	H-loop/switch region; other site
56110005000	TOBE-like domain; Region: TOBE_3; pfam12857
56110005001	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
56110005002	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
56110005003	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
56110005004	ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: Sbp; COG1613
56110005005	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
56110005006	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110005007	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110005008	structural tetrad; other site
56110005009	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
56110005010	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
56110005011	FtsX-like permease family; Region: FtsX; pfam02687
56110005012	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
56110005013	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
56110005014	Walker A/P-loop; other site
56110005015	ATP binding site [chemical binding]; other site
56110005016	Q-loop/lid; other site
56110005017	ABC transporter signature motif; other site
56110005018	Walker B; other site
56110005019	D-loop; other site
56110005020	H-loop/switch region; other site
56110005021	Response regulator receiver domain; Region: Response_reg; pfam00072
56110005022	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005023	active site
56110005024	phosphorylation site [posttranslational modification]
56110005025	intermolecular recognition site; other site
56110005026	dimerization interface [polypeptide binding]; other site
56110005027	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110005028	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110005029	metal binding site [ion binding]; metal-binding site
56110005030	active site
56110005031	I-site; other site
56110005032	HEAT repeats; Region: HEAT_2; pfam13646
56110005033	HEAT repeats; Region: HEAT_2; pfam13646
56110005034	HEAT repeats; Region: HEAT_2; pfam13646
56110005035	E-Z type HEAT repeats; Region: EZ_HEAT; smart00567
56110005036	FOG: CBS domain [General function prediction only]; Region: COG0517
56110005037	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection...; Region: CBS_pair_BON_assoc; cd04586
56110005038	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
56110005039	dimer interface [polypeptide binding]; other site
56110005040	[2Fe-2S] cluster binding site [ion binding]; other site
56110005041	hydrolase, alpha/beta fold family protein; Region: PLN02824
56110005042	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
56110005043	catalytic site [active]
56110005044	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
56110005045	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
56110005046	putative active site [active]
56110005047	putative metal binding site [ion binding]; other site
56110005048	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
56110005049	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
56110005050	NAD binding site [chemical binding]; other site
56110005051	substrate binding site [chemical binding]; other site
56110005052	homodimer interface [polypeptide binding]; other site
56110005053	active site
56110005054	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110005055	Predicted membrane protein [Function unknown]; Region: COG4083; cl15694
56110005056	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
56110005057	cyanosortase-associated protein; Region: cyanosort_assoc; TIGR04153
56110005058	Protein of unknown function (DUF456); Region: DUF456; pfam04306
56110005059	Protein of unknown function (DUF2930); Region: DUF2930; pfam11152
56110005060	Ycf27; Reviewed; Region: orf27; CHL00148
56110005061	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005062	active site
56110005063	phosphorylation site [posttranslational modification]
56110005064	intermolecular recognition site; other site
56110005065	dimerization interface [polypeptide binding]; other site
56110005066	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110005067	DNA binding site [nucleotide binding]
56110005068	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110005069	Walker A motif; other site
56110005070	ATP binding site [chemical binding]; other site
56110005071	DNA repair protein RadA; Provisional; Region: PRK11823
56110005072	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110005073	Walker B motif; other site
56110005074	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
56110005075	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110005076	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110005077	structural tetrad; other site
56110005078	Uncharacterized protein, putative amidase [General function prediction only]; Region: COG1402
56110005079	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110005080	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005081	active site
56110005082	phosphorylation site [posttranslational modification]
56110005083	intermolecular recognition site; other site
56110005084	dimerization interface [polypeptide binding]; other site
56110005085	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110005086	DNA binding site [nucleotide binding]
56110005087	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110005088	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110005089	dimer interface [polypeptide binding]; other site
56110005090	phosphorylation site [posttranslational modification]
56110005091	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110005092	ATP binding site [chemical binding]; other site
56110005093	Mg2+ binding site [ion binding]; other site
56110005094	G-X-G motif; other site
56110005095	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
56110005096	PhoU domain; Region: PhoU; pfam01895
56110005097	PhoU domain; Region: PhoU; pfam01895
56110005098	Predicted phosphatase [General function prediction only]; Region: PhoX; COG3211
56110005099	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK07428
56110005100	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
56110005101	dimerization interface [polypeptide binding]; other site
56110005102	active site
56110005103	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
56110005104	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
56110005105	metal binding site [ion binding]; metal-binding site
56110005106	dimer interface [polypeptide binding]; other site
56110005107	AAA domain; Region: AAA_26; pfam13500
56110005108	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
56110005109	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110005110	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110005111	active site
56110005112	ATP binding site [chemical binding]; other site
56110005113	substrate binding site [chemical binding]; other site
56110005114	activation loop (A-loop); other site
56110005115	Yqey-like protein; Region: YqeY; pfam09424
56110005116	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02812
56110005117	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
56110005118	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110005119	active site
56110005120	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
56110005121	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
56110005122	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
56110005123	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
56110005124	Predicted aspartyl protease [Posttranslational modification, protein turnover, chaperones]; Region: COG5550; cl17622
56110005125	Chloramphenicol (Cm) phosphotransferase (CPT). Cm-inactivating enzyme; modifies the primary (C-3) hydroxyl of the antibiotic. Related structurally to shikimate kinase II; Region: CPT; cl17391
56110005126	P-loop motif; other site
56110005127	ATP binding site [chemical binding]; other site
56110005128	Chloramphenicol (Cm) binding site [chemical binding]; other site
56110005129	catalytic residue [active]
56110005130	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
56110005131	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
56110005132	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
56110005133	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110005134	non-specific DNA binding site [nucleotide binding]; other site
56110005135	salt bridge; other site
56110005136	sequence-specific DNA binding site [nucleotide binding]; other site
56110005137	Clp amino terminal domain; Region: Clp_N; pfam02861
56110005138	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
56110005139	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
56110005140	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
56110005141	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
56110005142	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
56110005143	N-terminal domain interface [polypeptide binding]; other site
56110005144	dimer interface [polypeptide binding]; other site
56110005145	substrate binding pocket (H-site) [chemical binding]; other site
56110005146	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
56110005147	dimer interface [polypeptide binding]; other site
56110005148	[2Fe-2S] cluster binding site [ion binding]; other site
56110005149	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110005150	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110005151	S-adenosylmethionine binding site [chemical binding]; other site
56110005152	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
56110005153	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
56110005154	dimer interface [polypeptide binding]; other site
56110005155	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110005156	catalytic residue [active]
56110005157	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
56110005158	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
56110005159	dimer interface [polypeptide binding]; other site
56110005160	decamer (pentamer of dimers) interface [polypeptide binding]; other site
56110005161	catalytic triad [active]
56110005162	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR_like; cd08242
56110005163	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
56110005164	putative NAD(P) binding site [chemical binding]; other site
56110005165	catalytic Zn binding site [ion binding]; other site
56110005166	structural Zn binding site [ion binding]; other site
56110005167	SOUL heme-binding protein; Region: SOUL; pfam04832
56110005168	nitrogen fixation negative regulator NifL; Region: nifL_nitrog; TIGR02938
56110005169	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005170	putative active site [active]
56110005171	heme pocket [chemical binding]; other site
56110005172	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005173	putative active site [active]
56110005174	heme pocket [chemical binding]; other site
56110005175	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110005176	dimer interface [polypeptide binding]; other site
56110005177	phosphorylation site [posttranslational modification]
56110005178	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110005179	ATP binding site [chemical binding]; other site
56110005180	Mg2+ binding site [ion binding]; other site
56110005181	G-X-G motif; other site
56110005182	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
56110005183	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
56110005184	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
56110005185	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
56110005186	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110005187	catalytic residue [active]
56110005188	RecB family nuclease, putative, TM0106 family; Region: TIGR03491
56110005189	RNase_H superfamily; Region: RNase_H_2; pfam13482
56110005190	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
56110005191	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110005192	putative active site [active]
56110005193	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110005194	putative active site [active]
56110005195	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110005196	putative active site [active]
56110005197	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
56110005198	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
56110005199	HIGH motif; other site
56110005200	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
56110005201	active site
56110005202	KMSKS motif; other site
56110005203	Domain of unknown function (DUF4308); Region: DUF4308; pfam14159
56110005204	cell division protein; Validated; Region: ftsH; CHL00176
56110005205	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110005206	Walker A motif; other site
56110005207	ATP binding site [chemical binding]; other site
56110005208	Walker B motif; other site
56110005209	arginine finger; other site
56110005210	Peptidase family M41; Region: Peptidase_M41; pfam01434
56110005211	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110005212	Ligand Binding Site [chemical binding]; other site
56110005213	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
56110005214	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
56110005215	Surface antigen; Region: Bac_surface_Ag; pfam01103
56110005216	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
56110005217	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
56110005218	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110005219	ATP binding site [chemical binding]; other site
56110005220	putative Mg++ binding site [ion binding]; other site
56110005221	Uncharacterized conserved protein [Function unknown]; Region: COG2361
56110005222	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110005223	active site
56110005224	NTP binding site [chemical binding]; other site
56110005225	metal binding triad [ion binding]; metal-binding site
56110005226	antibiotic binding site [chemical binding]; other site
56110005227	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
56110005228	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
56110005229	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
56110005230	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
56110005231	HsdM N-terminal domain; Region: HsdM_N; pfam12161
56110005232	Methyltransferase domain; Region: Methyltransf_26; pfam13659
56110005233	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2402
56110005234	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110005235	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
56110005236	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
56110005237	Ion transport protein; Region: Ion_trans; pfam00520
56110005238	Ion channel; Region: Ion_trans_2; pfam07885
56110005239	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005240	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110005241	putative active site [active]
56110005242	heme pocket [chemical binding]; other site
56110005243	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110005244	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005245	putative active site [active]
56110005246	heme pocket [chemical binding]; other site
56110005247	PAS fold; Region: PAS_4; pfam08448
56110005248	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110005249	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110005250	dimer interface [polypeptide binding]; other site
56110005251	phosphorylation site [posttranslational modification]
56110005252	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110005253	ATP binding site [chemical binding]; other site
56110005254	Mg2+ binding site [ion binding]; other site
56110005255	G-X-G motif; other site
56110005256	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005257	PAS domain; Region: PAS_9; pfam13426
56110005258	putative active site [active]
56110005259	heme pocket [chemical binding]; other site
56110005260	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110005261	GAF domain; Region: GAF; pfam01590
56110005262	PAS domain S-box; Region: sensory_box; TIGR00229
56110005263	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005264	putative active site [active]
56110005265	heme pocket [chemical binding]; other site
56110005266	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110005267	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110005268	metal binding site [ion binding]; metal-binding site
56110005269	active site
56110005270	I-site; other site
56110005271	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110005272	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110005273	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
56110005274	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
56110005275	UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: GalU; COG1210
56110005276	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
56110005277	active site
56110005278	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
56110005279	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110005280	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110005281	dimerization interface [polypeptide binding]; other site
56110005282	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110005283	dimer interface [polypeptide binding]; other site
56110005284	phosphorylation site [posttranslational modification]
56110005285	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110005286	ATP binding site [chemical binding]; other site
56110005287	Mg2+ binding site [ion binding]; other site
56110005288	G-X-G motif; other site
56110005289	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110005290	non-specific DNA binding site [nucleotide binding]; other site
56110005291	salt bridge; other site
56110005292	sequence-specific DNA binding site [nucleotide binding]; other site
56110005293	Domain of unknown function (DUF955); Region: DUF955; cl01076
56110005294	Uncharacterized conserved protein [Function unknown]; Region: COG3937
56110005295	YCII-related domain; Region: YCII; cl00999
56110005296	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110005297	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110005298	structural tetrad; other site
56110005299	Type IV pilin PilA; Region: Pilin_PilA; pfam14245
56110005300	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
56110005301	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
56110005302	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
56110005303	PBP superfamily domain; Region: PBP_like_2; cl17296
56110005304	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110005305	non-specific DNA binding site [nucleotide binding]; other site
56110005306	salt bridge; other site
56110005307	sequence-specific DNA binding site [nucleotide binding]; other site
56110005308	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
56110005309	active site
56110005310	O-succinylbenzoic acid--CoA ligase; Reviewed; Region: PRK07445
56110005311	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
56110005312	acyl-activating enzyme (AAE) consensus motif; other site
56110005313	putative AMP binding site [chemical binding]; other site
56110005314	putative active site [active]
56110005315	putative CoA binding site [chemical binding]; other site
56110005316	O-succinylbenzoate synthase; Provisional; Region: PRK02714
56110005317	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
56110005318	active site
56110005319	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
56110005320	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Provisional; Region: PRK07419
56110005321	UbiA prenyltransferase family; Region: UbiA; pfam01040
56110005322	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
56110005323	Cytochrome P450; Region: p450; pfam00067
56110005324	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
56110005325	chorismate binding enzyme; Region: Chorismate_bind; cl10555
56110005326	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
56110005327	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
56110005328	dimer interface [polypeptide binding]; other site
56110005329	tetramer interface [polypeptide binding]; other site
56110005330	PYR/PP interface [polypeptide binding]; other site
56110005331	TPP binding site [chemical binding]; other site
56110005332	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
56110005333	TPP-binding site; other site
56110005334	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
56110005335	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
56110005336	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
56110005337	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110005338	catalytic residue [active]
56110005339	YacP-like NYN domain; Region: NYN_YacP; pfam05991
56110005340	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
56110005341	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
56110005342	Walker A/P-loop; other site
56110005343	ATP binding site [chemical binding]; other site
56110005344	Q-loop/lid; other site
56110005345	ABC transporter signature motif; other site
56110005346	Walker B; other site
56110005347	D-loop; other site
56110005348	H-loop/switch region; other site
56110005349	hypothetical protein; Provisional; Region: PRK13683
56110005350	D2 subunit  of photosystem II (PS II); Region: Photosystem-II_D2; cd09288
56110005351	D1 interface; other site
56110005352	chlorophyll binding site; other site
56110005353	pheophytin binding site; other site
56110005354	beta carotene binding site; other site
56110005355	cytochrome b559 beta interface; other site
56110005356	quinone binding site; other site
56110005357	cytochrome b559 alpha interface; other site
56110005358	protein J interface; other site
56110005359	protein H interface; other site
56110005360	protein X interface; other site
56110005361	core light harvesting protein interface; other site
56110005362	protein L interface; other site
56110005363	CP43 interface; other site
56110005364	protein T interface; other site
56110005365	Fe binding site [ion binding]; other site
56110005366	protein M interface; other site
56110005367	Mn-stabilizing polypeptide interface; other site
56110005368	bromide binding site; other site
56110005369	cytochrome c-550 interface; other site
56110005370	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH; cd00488
56110005371	aromatic arch; other site
56110005372	DCoH dimer interaction site [polypeptide binding]; other site
56110005373	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
56110005374	DCoH tetramer interaction site [polypeptide binding]; other site
56110005375	substrate binding site [chemical binding]; other site
56110005376	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110005377	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110005378	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
56110005379	Zn2+ binding site [ion binding]; other site
56110005380	Mg2+ binding site [ion binding]; other site
56110005381	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
56110005382	S-layer homology domain; Region: SLH; pfam00395
56110005383	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
56110005384	S-layer homology domain; Region: SLH; pfam00395
56110005385	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
56110005386	Predicted transcriptional regulator [Transcription]; Region: COG1959
56110005387	Transcriptional regulator; Region: Rrf2; pfam02082
56110005388	Peptidase family S48; Region: Peptidase_S48; cl11616
56110005389	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
56110005390	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
56110005391	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
56110005392	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
56110005393	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
56110005394	SLBB domain; Region: SLBB; pfam10531
56110005395	SLBB domain; Region: SLBB; pfam10531
56110005396	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
56110005397	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
56110005398	cyanoexosortase B; Region: cyanoexo_CrtB; TIGR04156
56110005399	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
56110005400	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
56110005401	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
56110005402	inhibitor-cofactor binding pocket; inhibition site
56110005403	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110005404	catalytic residue [active]
56110005405	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110005406	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110005407	choice-of-anchor A domain; Region: choice_anch_A; TIGR04215
56110005408	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110005409	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005410	PAS domain; Region: PAS_9; pfam13426
56110005411	putative active site [active]
56110005412	heme pocket [chemical binding]; other site
56110005413	PAS domain S-box; Region: sensory_box; TIGR00229
56110005414	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005415	putative active site [active]
56110005416	heme pocket [chemical binding]; other site
56110005417	PAS fold; Region: PAS; pfam00989
56110005418	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005419	putative active site [active]
56110005420	heme pocket [chemical binding]; other site
56110005421	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110005422	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110005423	dimer interface [polypeptide binding]; other site
56110005424	phosphorylation site [posttranslational modification]
56110005425	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110005426	ATP binding site [chemical binding]; other site
56110005427	G-X-G motif; other site
56110005428	Protein of unknown function (DUF3352); Region: DUF3352; pfam11832
56110005429	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110005430	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110005431	S-adenosylmethionine binding site [chemical binding]; other site
56110005432	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110005433	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
56110005434	HSP70 interaction site [polypeptide binding]; other site
56110005435	Domain of unknown function (DUF4383); Region: DUF4383; pfam14325
56110005436	methionine sulfoxide reductase A; Provisional; Region: PRK00058
56110005437	recA bacterial DNA recombination protein; Region: RecA; cl17211
56110005438	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
56110005439	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110005440	putative active site [active]
56110005441	Bacterial SH3 domain homologues; Region: SH3b; smart00287
56110005442	Ycf46; Provisional; Region: ycf46; CHL00195
56110005443	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110005444	Walker A motif; other site
56110005445	ATP binding site [chemical binding]; other site
56110005446	Walker B motif; other site
56110005447	arginine finger; other site
56110005448	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
56110005449	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
56110005450	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
56110005451	G-X-X-G motif; other site
56110005452	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
56110005453	RxxxH motif; other site
56110005454	putative inner membrane protein translocase component YidC; Provisional; Region: PRK02654
56110005455	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
56110005456	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
56110005457	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110005458	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110005459	Probable transposase; Region: OrfB_IS605; pfam01385
56110005460	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110005461	Bacterial PH domain; Region: DUF304; pfam03703
56110005462	ribonuclease P; Reviewed; Region: rnpA; PRK03031
56110005463	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
56110005464	Protein of unknown function (DUF2808); Region: DUF2808; pfam10989
56110005465	Amidases related to nicotinamidase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PncA; COG1335
56110005466	catalytic triad [active]
56110005467	conserved cis-peptide bond; other site
56110005468	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110005469	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110005470	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110005471	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110005472	Homeodomain-like domain; Region: HTH_23; pfam13384
56110005473	Winged helix-turn helix; Region: HTH_29; pfam13551
56110005474	arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291
56110005475	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
56110005476	P loop; other site
56110005477	Nucleotide binding site [chemical binding]; other site
56110005478	DTAP/Switch II; other site
56110005479	Switch I; other site
56110005480	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
56110005481	DTAP/Switch II; other site
56110005482	Switch I; other site
56110005483	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
56110005484	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110005485	dimerization interface [polypeptide binding]; other site
56110005486	putative DNA binding site [nucleotide binding]; other site
56110005487	putative Zn2+ binding site [ion binding]; other site
56110005488	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
56110005489	FAD binding site [chemical binding]; other site
56110005490	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
56110005491	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
56110005492	active site
56110005493	HIGH motif; other site
56110005494	dimer interface [polypeptide binding]; other site
56110005495	KMSKS motif; other site
56110005496	NAD-dependent deacetylase; Provisional; Region: PRK00481
56110005497	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
56110005498	Predicted nuclease (RNAse H fold) [General function prediction only]; Region: COG4328
56110005499	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
56110005500	putative homodimer interface [polypeptide binding]; other site
56110005501	putative active site pocket [active]
56110005502	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
56110005503	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110005504	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110005505	Probable transposase; Region: OrfB_IS605; pfam01385
56110005506	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110005507	Bacterial SH3 domain; Region: SH3_3; cl17532
56110005508	Uncharacterized conserved protein [Function unknown]; Region: COG3791
56110005509	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
56110005510	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
56110005511	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
56110005512	NAD binding site [chemical binding]; other site
56110005513	homodimer interface [polypeptide binding]; other site
56110005514	active site
56110005515	substrate binding site [chemical binding]; other site
56110005516	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
56110005517	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110005518	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110005519	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110005520	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
56110005521	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110005522	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
56110005523	Walker A/P-loop; other site
56110005524	ATP binding site [chemical binding]; other site
56110005525	Q-loop/lid; other site
56110005526	ABC transporter signature motif; other site
56110005527	Walker B; other site
56110005528	D-loop; other site
56110005529	H-loop/switch region; other site
56110005530	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
56110005531	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
56110005532	minor groove reading motif; other site
56110005533	helix-hairpin-helix signature motif; other site
56110005534	substrate binding pocket [chemical binding]; other site
56110005535	active site
56110005536	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
56110005537	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
56110005538	active site
56110005539	8-oxo-dGMP binding site [chemical binding]; other site
56110005540	nudix motif; other site
56110005541	metal binding site [ion binding]; metal-binding site
56110005542	Protein of unknown function (DUF760); Region: DUF760; pfam05542
56110005543	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110005544	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110005545	active site
56110005546	ATP binding site [chemical binding]; other site
56110005547	substrate binding site [chemical binding]; other site
56110005548	activation loop (A-loop); other site
56110005549	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110005550	structural tetrad; other site
56110005551	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
56110005552	calcium/proton exchanger (cax); Region: cax; TIGR00378
56110005553	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
56110005554	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
56110005555	Alpha-amylase/alpha-mannosidase [Carbohydrate transport and metabolism]; Region: COG1449
56110005556	N-terminal putative catalytic domain of mainly uncharacterized prokaryotic proteins similar to archaeal thermoactive amylopullulanases; glycoside hydrolase family 57 (GH57); Region: GH57N_APU_like_1; cd10797
56110005557	active site
56110005558	catalytic site [active]
56110005559	Domain of unknown function (DUF3536); Region: DUF3536; pfam12055
56110005560	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
56110005561	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
56110005562	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
56110005563	active site
56110005564	Substrate binding site; other site
56110005565	Mg++ binding site; other site
56110005566	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
56110005567	putative trimer interface [polypeptide binding]; other site
56110005568	putative CoA binding site [chemical binding]; other site
56110005569	arginine decarboxylase; Provisional; Region: PRK05354
56110005570	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
56110005571	dimer interface [polypeptide binding]; other site
56110005572	active site
56110005573	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
56110005574	catalytic residues [active]
56110005575	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
56110005576	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
56110005577	active site
56110005578	multimer interface [polypeptide binding]; other site
56110005579	Integral membrane protein TerC family; Region: TerC; cl10468
56110005580	Photosystem I protein M (PsaM); Region: PsaM; pfam07465
56110005581	TPR repeat; Region: TPR_11; pfam13414
56110005582	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005583	binding surface
56110005584	TPR motif; other site
56110005585	TPR repeat; Region: TPR_11; pfam13414
56110005586	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005587	binding surface
56110005588	TPR motif; other site
56110005589	TPR repeat; Region: TPR_11; pfam13414
56110005590	carboxyl-terminal processing protease; Provisional; Region: PLN00049
56110005591	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
56110005592	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
56110005593	protein binding site [polypeptide binding]; other site
56110005594	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
56110005595	Catalytic dyad [active]
56110005596	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110005597	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110005598	Probable transposase; Region: OrfB_IS605; pfam01385
56110005599	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110005600	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
56110005601	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
56110005602	Qi binding site; other site
56110005603	intrachain domain interface; other site
56110005604	interchain domain interface [polypeptide binding]; other site
56110005605	heme bH binding site [chemical binding]; other site
56110005606	heme bL binding site [chemical binding]; other site
56110005607	Qo binding site; other site
56110005608	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
56110005609	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cd00290
56110005610	interchain domain interface [polypeptide binding]; other site
56110005611	intrachain domain interface; other site
56110005612	Qi binding site; other site
56110005613	Qo binding site; other site
56110005614	CHAT domain; Region: CHAT; pfam12770
56110005615	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110005616	phosphopeptide binding site; other site
56110005617	Response regulator receiver domain; Region: Response_reg; pfam00072
56110005618	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005619	active site
56110005620	phosphorylation site [posttranslational modification]
56110005621	intermolecular recognition site; other site
56110005622	dimerization interface [polypeptide binding]; other site
56110005623	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110005624	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110005625	metal binding site [ion binding]; metal-binding site
56110005626	active site
56110005627	I-site; other site
56110005628	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110005629	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
56110005630	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
56110005631	FMN binding site [chemical binding]; other site
56110005632	active site
56110005633	catalytic residues [active]
56110005634	substrate binding site [chemical binding]; other site
56110005635	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
56110005636	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
56110005637	Zn2+ binding site [ion binding]; other site
56110005638	Mg2+ binding site [ion binding]; other site
56110005639	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
56110005640	synthetase active site [active]
56110005641	NTP binding site [chemical binding]; other site
56110005642	metal binding site [ion binding]; metal-binding site
56110005643	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
56110005644	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
56110005645	Transcription factor zinc-finger; Region: zf-TFIIB; cl01565
56110005646	Transcription factor zinc-finger; Region: zf-TFIIB; pfam13453
56110005647	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
56110005648	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
56110005649	Walker A/P-loop; other site
56110005650	ATP binding site [chemical binding]; other site
56110005651	Q-loop/lid; other site
56110005652	ABC transporter signature motif; other site
56110005653	Walker B; other site
56110005654	D-loop; other site
56110005655	H-loop/switch region; other site
56110005656	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
56110005657	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
56110005658	Walker A/P-loop; other site
56110005659	ATP binding site [chemical binding]; other site
56110005660	Q-loop/lid; other site
56110005661	ABC transporter signature motif; other site
56110005662	Walker B; other site
56110005663	D-loop; other site
56110005664	H-loop/switch region; other site
56110005665	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
56110005666	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110005667	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110005668	S-adenosylmethionine binding site [chemical binding]; other site
56110005669	hypothetical protein; Validated; Region: PRK07411
56110005670	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
56110005671	ATP binding site [chemical binding]; other site
56110005672	substrate interface [chemical binding]; other site
56110005673	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
56110005674	active site residue [active]
56110005675	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding); Region: MPN_like; cd08070
56110005676	MPN+ (JAMM) motif; other site
56110005677	Zinc-binding site [ion binding]; other site
56110005678	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110005679	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110005680	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110005681	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
56110005682	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
56110005683	NAD(P) binding site [chemical binding]; other site
56110005684	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
56110005685	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110005686	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; pfam02660
56110005687	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
56110005688	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
56110005689	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
56110005690	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110005691	NAD(P) binding site [chemical binding]; other site
56110005692	active site
56110005693	Response regulator receiver domain; Region: Response_reg; pfam00072
56110005694	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005695	active site
56110005696	phosphorylation site [posttranslational modification]
56110005697	intermolecular recognition site; other site
56110005698	dimerization interface [polypeptide binding]; other site
56110005699	nitrogen fixation negative regulator NifL; Region: nifL_nitrog; TIGR02938
56110005700	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110005701	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110005702	dimer interface [polypeptide binding]; other site
56110005703	phosphorylation site [posttranslational modification]
56110005704	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110005705	ATP binding site [chemical binding]; other site
56110005706	Mg2+ binding site [ion binding]; other site
56110005707	G-X-G motif; other site
56110005708	Response regulator receiver domain; Region: Response_reg; pfam00072
56110005709	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005710	active site
56110005711	phosphorylation site [posttranslational modification]
56110005712	intermolecular recognition site; other site
56110005713	dimerization interface [polypeptide binding]; other site
56110005714	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110005715	putative binding surface; other site
56110005716	active site
56110005717	Response regulator receiver domain; Region: Response_reg; pfam00072
56110005718	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005719	active site
56110005720	phosphorylation site [posttranslational modification]
56110005721	intermolecular recognition site; other site
56110005722	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110005723	dimerization interface [polypeptide binding]; other site
56110005724	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110005725	dimer interface [polypeptide binding]; other site
56110005726	phosphorylation site [posttranslational modification]
56110005727	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110005728	ATP binding site [chemical binding]; other site
56110005729	Mg2+ binding site [ion binding]; other site
56110005730	G-X-G motif; other site
56110005731	acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK07418
56110005732	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
56110005733	PYR/PP interface [polypeptide binding]; other site
56110005734	dimer interface [polypeptide binding]; other site
56110005735	TPP binding site [chemical binding]; other site
56110005736	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
56110005737	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
56110005738	TPP-binding site [chemical binding]; other site
56110005739	dimer interface [polypeptide binding]; other site
56110005740	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
56110005741	CO2 hydration protein (ChpXY); Region: ChpXY; pfam10216
56110005742	NAD(P)H-quinone oxidoreductase subunit D4; Validated; Region: PRK06473
56110005743	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110005744	NAD(P)H-quinone oxidoreductase subunit F; Validated; Region: PRK07390
56110005745	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110005746	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
56110005747	Carbon dioxide concentrating mechanism (CcmK); Bacterial Micro-Compartment (BCM) domain; Region: BMC_CcmK; cd07057
56110005748	Hexamer interface [polypeptide binding]; other site
56110005749	Hexagonal pore residue; other site
56110005750	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
56110005751	Carbon dioxide concentrating mechanism (CcmK); Bacterial Micro-Compartment (BCM) domain; Region: BMC_CcmK; cd07057
56110005752	Hexamer interface [polypeptide binding]; other site
56110005753	Hexagonal pore residue; other site
56110005754	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
56110005755	Hexamer/Pentamer interface [polypeptide binding]; other site
56110005756	central pore; other site
56110005757	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
56110005758	Gamma carbonic anhydrases (CA): Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed...; Region: LbH_gamma_CA; cd00710
56110005759	trimer interface [polypeptide binding]; other site
56110005760	active site
56110005761	Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit and related proteins. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of...; Region: RuBisCO_small_like; cd00307
56110005762	putative multimerization interface [polypeptide binding]; other site
56110005763	Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit and related proteins. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of...; Region: RuBisCO_small_like; cd00307
56110005764	putative multimerization interface [polypeptide binding]; other site
56110005765	Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit and related proteins. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of...; Region: RuBisCO_small_like; cd00307
56110005766	putative multimerization interface [polypeptide binding]; other site
56110005767	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
56110005768	putative trimer interface [polypeptide binding]; other site
56110005769	putative CoA binding site [chemical binding]; other site
56110005770	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
56110005771	Carbon dioxide concentrating mechanism (CcmK); Bacterial Micro-Compartment (BCM) domain; Region: BMC_CcmK; cd07057
56110005772	Hexamer interface [polypeptide binding]; other site
56110005773	Hexagonal pore residue; other site
56110005774	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
56110005775	Carbon dioxide concentrating mechanism (CcmK); Bacterial Micro-Compartment (BCM) domain; Region: BMC_CcmK; cd07057
56110005776	Hexamer interface [polypeptide binding]; other site
56110005777	Hexagonal pore residue; other site
56110005778	short chain dehydrogenase; Provisional; Region: PRK06701
56110005779	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
56110005780	NAD binding site [chemical binding]; other site
56110005781	metal binding site [ion binding]; metal-binding site
56110005782	active site
56110005783	Hemerythrin-like domain; Region: Hr-like; cd12108
56110005784	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
56110005785	DNA protecting protein DprA; Region: dprA; TIGR00732
56110005786	D-inositol-3-phosphate glycosyltransferase; Region: mycothiol_MshA; TIGR03449
56110005787	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
56110005788	putative ADP-binding pocket [chemical binding]; other site
56110005789	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110005790	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110005791	Uncharacterized integral membrane protein (DUF2301); Region: DUF2301; cl02241
56110005792	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; pfam01887
56110005793	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
56110005794	pyruvate dehydrogenase E1 component beta subunit; Validated; Region: odpB; CHL00144
56110005795	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
56110005796	alpha subunit interface [polypeptide binding]; other site
56110005797	TPP binding site [chemical binding]; other site
56110005798	heterodimer interface [polypeptide binding]; other site
56110005799	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
56110005800	protein-export membrane protein SecD; Region: secD; TIGR01129
56110005801	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
56110005802	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
56110005803	Protein export membrane protein; Region: SecD_SecF; pfam02355
56110005804	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110005805	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110005806	Uncharacterized conserved protein [Function unknown]; Region: COG0327
56110005807	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
56110005808	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
56110005809	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
56110005810	The C-terminal domain of a subfamily of Na+ /H+ antiporter existed in bacteria and archea . Na+/H+ exchange proteins eject protons from cells, effectively eliminating excess acid from actively metabolising cells. Na+ /H+ exchange activity is also crucial...; Region: Na_H_Antiporter_C; cd01988
56110005811	Ligand Binding Site [chemical binding]; other site
56110005812	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
56110005813	Domain of unknown function DUF20; Region: UPF0118; pfam01594
56110005814	magnesium chelatase ATPase subunit D; Region: BchD-ChlD; TIGR02031
56110005815	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110005816	Walker B motif; other site
56110005817	arginine finger; other site
56110005818	Magnesium chelatase: Mg-chelatase catalyses the insertion of Mg into protoporphyrin IX (Proto). In chlorophyll biosynthesis, insertion of Mg2+ into protoporphyrin IX is catalysed by magnesium chelatase in an ATP-dependent reaction. Magnesium chelatase is...; Region: vWA_Magnesium_chelatase; cd01451
56110005819	metal ion-dependent adhesion site (MIDAS); other site
56110005820	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110005821	Coenzyme A binding pocket [chemical binding]; other site
56110005822	Transposase domain (DUF772); Region: DUF772; pfam05598
56110005823	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
56110005824	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
56110005825	Protein of unknown function (DUF3153); Region: DUF3153; pfam11353
56110005826	Response regulator receiver domain; Region: Response_reg; pfam00072
56110005827	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110005828	active site
56110005829	phosphorylation site [posttranslational modification]
56110005830	intermolecular recognition site; other site
56110005831	dimerization interface [polypeptide binding]; other site
56110005832	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110005833	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110005834	active site
56110005835	ATP binding site [chemical binding]; other site
56110005836	substrate binding site [chemical binding]; other site
56110005837	activation loop (A-loop); other site
56110005838	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110005839	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110005840	structural tetrad; other site
56110005841	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110005842	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110005843	active site
56110005844	ATP binding site [chemical binding]; other site
56110005845	substrate binding site [chemical binding]; other site
56110005846	activation loop (A-loop); other site
56110005847	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
56110005848	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110005849	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110005850	active site
56110005851	ATP binding site [chemical binding]; other site
56110005852	substrate binding site [chemical binding]; other site
56110005853	activation loop (A-loop); other site
56110005854	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110005855	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110005856	structural tetrad; other site
56110005857	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110005858	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110005859	active site
56110005860	ATP binding site [chemical binding]; other site
56110005861	substrate binding site [chemical binding]; other site
56110005862	activation loop (A-loop); other site
56110005863	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110005864	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110005865	structural tetrad; other site
56110005866	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
56110005867	PHP domain; Region: PHP; pfam02811
56110005868	active site
56110005869	PHP Thumb interface [polypeptide binding]; other site
56110005870	metal binding site [ion binding]; metal-binding site
56110005871	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
56110005872	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110005873	protein-splicing catalytic site; other site
56110005874	thioester formation/cholesterol transfer; other site
56110005875	DNA polymerase III subunit alpha; Reviewed; Region: PRK07373
56110005876	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
56110005877	generic binding surface I; other site
56110005878	generic binding surface II; other site
56110005879	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
56110005880	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
56110005881	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
56110005882	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
56110005883	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
56110005884	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
56110005885	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
56110005886	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
56110005887	DNA binding residues [nucleotide binding]
56110005888	Precorrin isomerase [Coenzyme metabolism]; Region: CobH; COG2082
56110005889	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
56110005890	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
56110005891	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
56110005892	Soluble P-type ATPase [General function prediction only]; Region: COG4087
56110005893	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
56110005894	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
56110005895	RNA binding surface [nucleotide binding]; other site
56110005896	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
56110005897	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
56110005898	Leucine-rich repeats; other site
56110005899	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005900	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005901	Substrate binding site [chemical binding]; other site
56110005902	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005903	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005904	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005905	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005906	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005907	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
56110005908	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005909	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005910	Substrate binding site [chemical binding]; other site
56110005911	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005912	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005913	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110005914	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110005915	allophycocyanin, beta subunit; Region: apcB; TIGR01337
56110005916	glutamine synthetase, type I; Region: GlnA; TIGR00653
56110005917	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
56110005918	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
56110005919	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110005920	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110005921	S-adenosylmethionine binding site [chemical binding]; other site
56110005922	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
56110005923	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
56110005924	Divergent AAA domain; Region: AAA_4; pfam04326
56110005925	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
56110005926	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
56110005927	Protein of unknown function (DUF2281); Region: DUF2281; cl02355
56110005928	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
56110005929	SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell...; Region: S2P-M50_SpoIVFB_CBS; cd06164
56110005930	active site
56110005931	Peptidase family M50; Region: Peptidase_M50; pfam02163
56110005932	putative substrate binding region [chemical binding]; other site
56110005933	FOG: CBS domain [General function prediction only]; Region: COG0517
56110005934	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the metalloprotease peptidase M50.  CBS is a small domain originally identified in cystathionine beta-synthase and subsequently found in a wide...; Region: CBS_pair_M50_like; cd04801
56110005935	Photosystem I psaG / psaK; Region: PSI_PSAK; cl11425
56110005936	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
56110005937	active site
56110005938	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
56110005939	homodecamer interface [polypeptide binding]; other site
56110005940	GTP cyclohydrolase I; Provisional; Region: PLN03044
56110005941	active site
56110005942	putative catalytic site residues [active]
56110005943	zinc binding site [ion binding]; other site
56110005944	GTP-CH-I/GFRP interaction surface; other site
56110005945	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
56110005946	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
56110005947	acyl-ACP reductase; Provisional; Region: PRK14982
56110005948	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
56110005949	NAD(P) binding pocket [chemical binding]; other site
56110005950	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
56110005951	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
56110005952	B12 binding site [chemical binding]; other site
56110005953	Domain of unknown function (DUF4070); Region: DUF4070; pfam13282
56110005954	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
56110005955	dinuclear metal binding motif [ion binding]; other site
56110005956	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
56110005957	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110005958	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110005959	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
56110005960	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
56110005961	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
56110005962	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110005963	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110005964	active site
56110005965	ATP binding site [chemical binding]; other site
56110005966	substrate binding site [chemical binding]; other site
56110005967	activation loop (A-loop); other site
56110005968	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
56110005969	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110005970	putative active site [active]
56110005971	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
56110005972	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110005973	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110005974	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110005975	TPR repeat; Region: TPR_11; pfam13414
56110005976	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005977	binding surface
56110005978	TPR motif; other site
56110005979	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005980	binding surface
56110005981	TPR motif; other site
56110005982	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110005983	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005984	binding surface
56110005985	TPR motif; other site
56110005986	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005987	TPR motif; other site
56110005988	binding surface
56110005989	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005990	binding surface
56110005991	TPR motif; other site
56110005992	TPR repeat; Region: TPR_11; pfam13414
56110005993	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005994	binding surface
56110005995	TPR motif; other site
56110005996	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110005997	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110005998	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110005999	binding surface
56110006000	TPR motif; other site
56110006001	TPR repeat; Region: TPR_11; pfam13414
56110006002	Domain of unknown function (DUF3598); Region: DUF3598; pfam12204
56110006003	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
56110006004	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
56110006005	TIGR02588 family protein; Region: TIGR02588
56110006006	Putative integral membrane protein (DUF2391); Region: DUF2391; pfam09622
56110006007	ribosomal protein S14; Region: rps14; CHL00074
56110006008	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
56110006009	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110006010	Walker A/P-loop; other site
56110006011	ATP binding site [chemical binding]; other site
56110006012	PAS domain S-box; Region: sensory_box; TIGR00229
56110006013	PAS domain S-box; Region: sensory_box; TIGR00229
56110006014	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006015	putative active site [active]
56110006016	heme pocket [chemical binding]; other site
56110006017	PAS domain; Region: PAS_9; pfam13426
56110006018	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006019	GAF domain; Region: GAF; pfam01590
56110006020	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006021	dimer interface [polypeptide binding]; other site
56110006022	phosphorylation site [posttranslational modification]
56110006023	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006024	ATP binding site [chemical binding]; other site
56110006025	Mg2+ binding site [ion binding]; other site
56110006026	G-X-G motif; other site
56110006027	Response regulator receiver domain; Region: Response_reg; pfam00072
56110006028	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006029	active site
56110006030	phosphorylation site [posttranslational modification]
56110006031	intermolecular recognition site; other site
56110006032	dimerization interface [polypeptide binding]; other site
56110006033	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110006034	putative binding surface; other site
56110006035	active site
56110006036	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006037	active site
56110006038	phosphorylation site [posttranslational modification]
56110006039	intermolecular recognition site; other site
56110006040	dimerization interface [polypeptide binding]; other site
56110006041	GAF domain; Region: GAF; cl17456
56110006042	GAF domain; Region: GAF_2; pfam13185
56110006043	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110006044	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006045	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006046	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
56110006047	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
56110006048	minor groove reading motif; other site
56110006049	helix-hairpin-helix signature motif; other site
56110006050	substrate binding pocket [chemical binding]; other site
56110006051	active site
56110006052	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
56110006053	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
56110006054	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
56110006055	active site
56110006056	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
56110006057	protein binding site [polypeptide binding]; other site
56110006058	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
56110006059	seryl-tRNA synthetase; Provisional; Region: PRK05431
56110006060	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
56110006061	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
56110006062	dimer interface [polypeptide binding]; other site
56110006063	active site
56110006064	motif 1; other site
56110006065	motif 2; other site
56110006066	motif 3; other site
56110006067	FOG: CBS domain [General function prediction only]; Region: COG0517
56110006068	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110006069	FOG: CBS domain [General function prediction only]; Region: COG0517
56110006070	FOG: CBS domain [General function prediction only]; Region: COG0517
56110006071	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with a PAS domain, a GGDEF (DiGuanylate-Cyclase (DGC) domain, and a DUF1 domain downstream. PAS domains have been found to bind ligands, and to act...; Region: CBS_pair_PAS_GGDEF_DUF1_assoc; cd04611
56110006072	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
56110006073	dimer interface [polypeptide binding]; other site
56110006074	phosphorylation site [posttranslational modification]
56110006075	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006076	ATP binding site [chemical binding]; other site
56110006077	Mg2+ binding site [ion binding]; other site
56110006078	G-X-G motif; other site
56110006079	2TM domain; Region: 2TM; pfam13239
56110006080	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4370
56110006081	conserved hypothetical protein; Region: TIGR03492
56110006082	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110006083	putative active site [active]
56110006084	Ub domain fused to Mut7-C; Region: Ub-Mut7C; pfam14451
56110006085	Uncharacterized conserved protein [Function unknown]; Region: COG1656
56110006086	Protein of unknown function DUF82; Region: DUF82; pfam01927
56110006087	2-phosphosulfolactate phosphatase; Provisional; Region: PRK00886
56110006088	Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Region: COG2045
56110006089	Alkaline and neutral invertase; Region: Glyco_hydro_100; pfam12899
56110006090	Repair protein; Region: Repair_PSII; pfam04536
56110006091	Repair protein; Region: Repair_PSII; pfam04536
56110006092	Repair protein; Region: Repair_PSII; pfam04536
56110006093	LemA family; Region: LemA; cl00742
56110006094	Protein of unknown function, DUF399; Region: DUF399; pfam04187
56110006095	Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate inositol monophosphate or similar substrates; Region: Bacterial_IMPase_like_2; cd01643
56110006096	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
56110006097	active site
56110006098	PUCC protein; Region: PUCC; pfam03209
56110006099	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110006100	putative substrate translocation pore; other site
56110006101	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110006102	Calx-beta domain; Region: Calx-beta; cl02522
56110006103	Domains in Na-Ca exchangers and integrin-beta4; Region: Calx_beta; smart00237
56110006104	Calx-beta domain; Region: Calx-beta; cl02522
56110006105	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110006106	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110006107	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110006108	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
56110006109	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
56110006110	active site
56110006111	catalytic tetrad [active]
56110006112	PAS domain S-box; Region: sensory_box; TIGR00229
56110006113	PAS domain; Region: PAS; smart00091
56110006114	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006115	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
56110006116	dimer interface [polypeptide binding]; other site
56110006117	phosphorylation site [posttranslational modification]
56110006118	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006119	ATP binding site [chemical binding]; other site
56110006120	Mg2+ binding site [ion binding]; other site
56110006121	G-X-G motif; other site
56110006122	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006123	putative active site [active]
56110006124	heme pocket [chemical binding]; other site
56110006125	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006126	GAF domain; Region: GAF_3; pfam13492
56110006127	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006128	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006129	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006130	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006131	dimer interface [polypeptide binding]; other site
56110006132	phosphorylation site [posttranslational modification]
56110006133	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006134	ATP binding site [chemical binding]; other site
56110006135	Mg2+ binding site [ion binding]; other site
56110006136	G-X-G motif; other site
56110006137	phosphoglycolate phosphatase; Provisional; Region: PRK13225
56110006138	NurA nuclease; Region: NurA; smart00933
56110006139	Exonuclease VII small subunit [DNA replication, recombination, and repair]; Region: XseB; COG1722
56110006140	Predicted metal-binding protein (DUF2103); Region: DUF2103; cl01651
56110006141	ATP-dependent Clp protease adaptor; Reviewed; Region: clpS; PRK13019
56110006142	Response regulator receiver domain; Region: Response_reg; pfam00072
56110006143	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006144	active site
56110006145	phosphorylation site [posttranslational modification]
56110006146	intermolecular recognition site; other site
56110006147	dimerization interface [polypeptide binding]; other site
56110006148	Heme NO binding associated; Region: HNOBA; pfam07701
56110006149	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110006150	cyclase homology domain; Region: CHD; cd07302
56110006151	nucleotidyl binding site; other site
56110006152	metal binding site [ion binding]; metal-binding site
56110006153	dimer interface [polypeptide binding]; other site
56110006154	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006155	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110006156	putative active site [active]
56110006157	heme pocket [chemical binding]; other site
56110006158	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006159	putative active site [active]
56110006160	heme pocket [chemical binding]; other site
56110006161	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110006162	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006163	putative active site [active]
56110006164	heme pocket [chemical binding]; other site
56110006165	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110006166	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006167	putative active site [active]
56110006168	heme pocket [chemical binding]; other site
56110006169	PAS domain S-box; Region: sensory_box; TIGR00229
56110006170	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006171	putative active site [active]
56110006172	heme pocket [chemical binding]; other site
56110006173	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006174	dimer interface [polypeptide binding]; other site
56110006175	phosphorylation site [posttranslational modification]
56110006176	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006177	ATP binding site [chemical binding]; other site
56110006178	Mg2+ binding site [ion binding]; other site
56110006179	G-X-G motif; other site
56110006180	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110006181	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006182	active site
56110006183	phosphorylation site [posttranslational modification]
56110006184	intermolecular recognition site; other site
56110006185	dimerization interface [polypeptide binding]; other site
56110006186	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
56110006187	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
56110006188	Walker A/P-loop; other site
56110006189	ATP binding site [chemical binding]; other site
56110006190	Q-loop/lid; other site
56110006191	ABC transporter signature motif; other site
56110006192	Walker B; other site
56110006193	D-loop; other site
56110006194	H-loop/switch region; other site
56110006195	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110006196	dimer interface [polypeptide binding]; other site
56110006197	conserved gate region; other site
56110006198	ABC-ATPase subunit interface; other site
56110006199	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
56110006200	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
56110006201	active site
56110006202	dimer interface [polypeptide binding]; other site
56110006203	metal binding site [ion binding]; metal-binding site
56110006204	tellurite resistance protein terB; Region: terB; cd07176
56110006205	putative metal binding site [ion binding]; other site
56110006206	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110006207	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110006208	active site
56110006209	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
56110006210	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
56110006211	C-terminal domain interface [polypeptide binding]; other site
56110006212	GSH binding site (G-site) [chemical binding]; other site
56110006213	dimer interface [polypeptide binding]; other site
56110006214	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
56110006215	N-terminal domain interface [polypeptide binding]; other site
56110006216	dimer interface [polypeptide binding]; other site
56110006217	substrate binding pocket (H-site) [chemical binding]; other site
56110006218	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110006219	active site
56110006220	Transposase; Region: HTH_Tnp_1; cl17663
56110006221	Homeodomain-like domain; Region: HTH_23; pfam13384
56110006222	Winged helix-turn helix; Region: HTH_29; pfam13551
56110006223	Winged helix-turn helix; Region: HTH_33; pfam13592
56110006224	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110006225	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110006226	mycothiol synthase; Region: mycothiol_MshD; TIGR03448
56110006227	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110006228	Coenzyme A binding pocket [chemical binding]; other site
56110006229	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
56110006230	metal ion-dependent adhesion site (MIDAS); other site
56110006231	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
56110006232	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
56110006233	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
56110006234	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
56110006235	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
56110006236	beta-phosphoglucomutase; Region: bPGM; TIGR01990
56110006237	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
56110006238	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110006239	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250
56110006240	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
56110006241	active site
56110006242	Zn binding site [ion binding]; other site
56110006243	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110006244	putative active site [active]
56110006245	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
56110006246	HsdM N-terminal domain; Region: HsdM_N; pfam12161
56110006247	Methyltransferase domain; Region: Methyltransf_26; pfam13659
56110006248	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
56110006249	Fic family protein [Function unknown]; Region: COG3177
56110006250	Fic/DOC family; Region: Fic; pfam02661
56110006251	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110006252	putative active site [active]
56110006253	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110006254	active site
56110006255	NTP binding site [chemical binding]; other site
56110006256	metal binding triad [ion binding]; metal-binding site
56110006257	antibiotic binding site [chemical binding]; other site
56110006258	Protein of unknown function DUF86; Region: DUF86; cl01031
56110006259	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
56110006260	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
56110006261	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110006262	ATP binding site [chemical binding]; other site
56110006263	putative Mg++ binding site [ion binding]; other site
56110006264	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110006265	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006266	active site
56110006267	ATP binding site [chemical binding]; other site
56110006268	substrate binding site [chemical binding]; other site
56110006269	activation loop (A-loop); other site
56110006270	PAS domain; Region: PAS; smart00091
56110006271	PAS fold; Region: PAS; pfam00989
56110006272	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110006273	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110006274	metal binding site [ion binding]; metal-binding site
56110006275	active site
56110006276	I-site; other site
56110006277	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110006278	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110006279	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
56110006280	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_9; cd07245
56110006281	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
56110006282	dimer interface [polypeptide binding]; other site
56110006283	putative metal binding site [ion binding]; other site
56110006284	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
56110006285	Resolvase, N terminal domain; Region: Resolvase; smart00857
56110006286	catalytic residues [active]
56110006287	Recombinase; Region: Recombinase; pfam07508
56110006288	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
56110006289	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006290	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006291	dimer interface [polypeptide binding]; other site
56110006292	phosphorylation site [posttranslational modification]
56110006293	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006294	ATP binding site [chemical binding]; other site
56110006295	Mg2+ binding site [ion binding]; other site
56110006296	G-X-G motif; other site
56110006297	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
56110006298	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
56110006299	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110006300	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
56110006301	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
56110006302	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
56110006303	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
56110006304	dimer interface [polypeptide binding]; other site
56110006305	motif 1; other site
56110006306	active site
56110006307	motif 2; other site
56110006308	motif 3; other site
56110006309	Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600
56110006310	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
56110006311	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
56110006312	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
56110006313	Walker A/P-loop; other site
56110006314	ATP binding site [chemical binding]; other site
56110006315	Q-loop/lid; other site
56110006316	ABC transporter signature motif; other site
56110006317	Walker B; other site
56110006318	D-loop; other site
56110006319	H-loop/switch region; other site
56110006320	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
56110006321	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110006322	dimer interface [polypeptide binding]; other site
56110006323	conserved gate region; other site
56110006324	putative PBP binding loops; other site
56110006325	ABC-ATPase subunit interface; other site
56110006326	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
56110006327	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
56110006328	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110006329	putative active site [active]
56110006330	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
56110006331	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110006332	Coenzyme A binding pocket [chemical binding]; other site
56110006333	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110006334	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110006335	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110006336	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
56110006337	Coenzyme A binding pocket [chemical binding]; other site
56110006338	ChrR Cupin-like domain; Region: Cupin_7; pfam12973
56110006339	SnoaL-like domain; Region: SnoaL_3; pfam13474
56110006340	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
56110006341	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
56110006342	tetramer interface [polypeptide binding]; other site
56110006343	active site
56110006344	Mg2+/Mn2+ binding site [ion binding]; other site
56110006345	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
56110006346	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02649
56110006347	ATP-NAD kinase; Region: NAD_kinase; pfam01513
56110006348	Ycf39; Provisional; Region: ycf39; CHL00194
56110006349	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
56110006350	NAD(P) binding site [chemical binding]; other site
56110006351	putative active site [active]
56110006352	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
56110006353	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
56110006354	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006355	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110006356	active site
56110006357	ATP binding site [chemical binding]; other site
56110006358	substrate binding site [chemical binding]; other site
56110006359	activation loop (A-loop); other site
56110006360	AAA ATPase domain; Region: AAA_16; pfam13191
56110006361	Predicted ATPase [General function prediction only]; Region: COG3899
56110006362	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006363	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006364	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110006365	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110006366	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006367	active site
56110006368	ATP binding site [chemical binding]; other site
56110006369	substrate binding site [chemical binding]; other site
56110006370	Protein kinase domain; Region: Pkinase; pfam00069
56110006371	activation loop (A-loop); other site
56110006372	Predicted ATPase [General function prediction only]; Region: COG3899
56110006373	AAA ATPase domain; Region: AAA_16; pfam13191
56110006374	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110006375	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006376	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006377	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110006378	cyclase homology domain; Region: CHD; cd07302
56110006379	nucleotidyl binding site; other site
56110006380	metal binding site [ion binding]; metal-binding site
56110006381	dimer interface [polypeptide binding]; other site
56110006382	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006383	active site
56110006384	ATP binding site [chemical binding]; other site
56110006385	substrate binding site [chemical binding]; other site
56110006386	Tyrosine kinase, catalytic domain; Region: TyrKc; smart00219
56110006387	activation loop (A-loop); other site
56110006388	AAA ATPase domain; Region: AAA_16; pfam13191
56110006389	Predicted ATPase [General function prediction only]; Region: COG3899
56110006390	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110006391	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006392	GAF domain; Region: GAF_2; pfam13185
56110006393	PAS domain; Region: PAS_9; pfam13426
56110006394	cyclase homology domain; Region: CHD; cd07302
56110006395	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110006396	nucleotidyl binding site; other site
56110006397	metal binding site [ion binding]; metal-binding site
56110006398	dimer interface [polypeptide binding]; other site
56110006399	lipoyl synthase; Provisional; Region: PRK12928
56110006400	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110006401	FeS/SAM binding site; other site
56110006402	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110006403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006404	active site
56110006405	phosphorylation site [posttranslational modification]
56110006406	intermolecular recognition site; other site
56110006407	dimerization interface [polypeptide binding]; other site
56110006408	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
56110006409	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
56110006410	putative ribose interaction site [chemical binding]; other site
56110006411	putative ADP binding site [chemical binding]; other site
56110006412	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
56110006413	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
56110006414	ATP binding site [chemical binding]; other site
56110006415	Mg2+ binding site [ion binding]; other site
56110006416	G-X-G motif; other site
56110006417	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
56110006418	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
56110006419	putative dimer interface [polypeptide binding]; other site
56110006420	putative anticodon binding site; other site
56110006421	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
56110006422	homodimer interface [polypeptide binding]; other site
56110006423	motif 1; other site
56110006424	motif 2; other site
56110006425	active site
56110006426	motif 3; other site
56110006427	Predicted permeases [General function prediction only]; Region: COG0795
56110006428	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
56110006429	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
56110006430	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
56110006431	Walker A/P-loop; other site
56110006432	ATP binding site [chemical binding]; other site
56110006433	Q-loop/lid; other site
56110006434	ABC transporter signature motif; other site
56110006435	Walker B; other site
56110006436	D-loop; other site
56110006437	H-loop/switch region; other site
56110006438	OstA-like protein; Region: OstA; pfam03968
56110006439	Domains in Na-Ca exchangers and integrin-beta4; Region: Calx_beta; smart00237
56110006440	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110006441	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006442	active site
56110006443	phosphorylation site [posttranslational modification]
56110006444	intermolecular recognition site; other site
56110006445	dimerization interface [polypeptide binding]; other site
56110006446	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110006447	DNA binding site [nucleotide binding]
56110006448	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006449	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006450	dimer interface [polypeptide binding]; other site
56110006451	phosphorylation site [posttranslational modification]
56110006452	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006453	ATP binding site [chemical binding]; other site
56110006454	Mg2+ binding site [ion binding]; other site
56110006455	G-X-G motif; other site
56110006456	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
56110006457	catalytic triad [active]
56110006458	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
56110006459	Domain of unknown function (DUF309); Region: DUF309; pfam03745
56110006460	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110006461	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110006462	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006463	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006464	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006465	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006466	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006467	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110006468	homoserine kinase; Provisional; Region: PRK01212
56110006469	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
56110006470	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
56110006471	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
56110006472	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
56110006473	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
56110006474	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
56110006475	homodimer interface [polypeptide binding]; other site
56110006476	substrate-cofactor binding pocket; other site
56110006477	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110006478	catalytic residue [active]
56110006479	NAD(P)H-quinone oxidoreductase subunit 4; Provisional; Region: PRK12561
56110006480	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110006481	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
56110006482	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
56110006483	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110006484	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110006485	Phosphotransferase enzyme family; Region: APH; pfam01636
56110006486	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
56110006487	active site
56110006488	ATP binding site [chemical binding]; other site
56110006489	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
56110006490	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110006491	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110006492	active site
56110006493	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110006494	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110006495	active site
56110006496	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
56110006497	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
56110006498	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
56110006499	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
56110006500	VPS10 domain; Region: VPS10; smart00602
56110006501	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
56110006502	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
56110006503	Protein of unknown function DUF86; Region: DUF86; cl01031
56110006504	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110006505	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110006506	dimer interface [polypeptide binding]; other site
56110006507	putative CheW interface [polypeptide binding]; other site
56110006508	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
56110006509	putative rRNA binding site [nucleotide binding]; other site
56110006510	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
56110006511	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
56110006512	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110006513	catalytic residue [active]
56110006514	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
56110006515	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110006516	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
56110006517	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
56110006518	catalytic site [active]
56110006519	putative active site [active]
56110006520	putative substrate binding site [chemical binding]; other site
56110006521	RNA polymerase sigma factor SigF; Reviewed; Region: PRK07408
56110006522	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110006523	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
56110006524	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110006525	DNA binding residues [nucleotide binding]
56110006526	Protein of unknown function (DUF3285); Region: DUF3285; pfam11688
56110006527	metal-binding heat shock protein; Provisional; Region: PRK00016
56110006528	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
56110006529	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
56110006530	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
56110006531	glutamine binding [chemical binding]; other site
56110006532	catalytic triad [active]
56110006533	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
56110006534	Beta-lactamase superfamily domain; Region: Lactamase_B_3; pfam13483
56110006535	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
56110006536	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
56110006537	Walker A/P-loop; other site
56110006538	ATP binding site [chemical binding]; other site
56110006539	Q-loop/lid; other site
56110006540	ABC transporter signature motif; other site
56110006541	Walker B; other site
56110006542	D-loop; other site
56110006543	H-loop/switch region; other site
56110006544	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110006545	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110006546	Probable transposase; Region: OrfB_IS605; pfam01385
56110006547	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110006548	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
56110006549	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
56110006550	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110006551	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110006552	binding surface
56110006553	TPR motif; other site
56110006554	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110006555	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110006556	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110006557	TPR motif; other site
56110006558	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110006559	binding surface
56110006560	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110006561	CHAT domain; Region: CHAT; pfam12770
56110006562	MgtC family; Region: MgtC; pfam02308
56110006563	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
56110006564	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
56110006565	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
56110006566	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
56110006567	AMIN domain; Region: AMIN; pfam11741
56110006568	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
56110006569	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
56110006570	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
56110006571	IHF dimer interface [polypeptide binding]; other site
56110006572	IHF - DNA interface [nucleotide binding]; other site
56110006573	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
56110006574	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110006575	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110006576	homodimer interface [polypeptide binding]; other site
56110006577	catalytic residue [active]
56110006578	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
56110006579	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110006580	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
56110006581	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
56110006582	Domain of unknown function DUF21; Region: DUF21; pfam01595
56110006583	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
56110006584	Transporter associated domain; Region: CorC_HlyC; smart01091
56110006585	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
56110006586	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
56110006587	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110006588	ATP binding site [chemical binding]; other site
56110006589	putative Mg++ binding site [ion binding]; other site
56110006590	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110006591	nucleotide binding region [chemical binding]; other site
56110006592	ATP-binding site [chemical binding]; other site
56110006593	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
56110006594	GTPase CgtA; Reviewed; Region: obgE; PRK12297
56110006595	TIGR04255 family protein; Region: sporadTIGR04255
56110006596	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
56110006597	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
56110006598	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
56110006599	precorrin-8X methylmutase; Validated; Region: PRK05953
56110006600	Precorrin-8X methylmutase; Region: CbiC; pfam02570
56110006601	dihydrodipicolinate reductase; Provisional; Region: PRK00048
56110006602	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
56110006603	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
56110006604	CHASE2 domain; Region: CHASE2; pfam05226
56110006605	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110006606	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110006607	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110006608	metal binding site [ion binding]; metal-binding site
56110006609	active site
56110006610	I-site; other site
56110006611	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110006612	Mg-protoporyphyrin IX chelatase; Region: chlI; CHL00081
56110006613	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
56110006614	Walker A motif; other site
56110006615	ATP binding site [chemical binding]; other site
56110006616	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
56110006617	active site
56110006618	putative DNA-binding cleft [nucleotide binding]; other site
56110006619	dimer interface [polypeptide binding]; other site
56110006620	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
56110006621	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
56110006622	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110006623	phosphopeptide binding site; other site
56110006624	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
56110006625	Active_site [active]
56110006626	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
56110006627	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
56110006628	Cytochrome P450; Region: p450; cl12078
56110006629	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
56110006630	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
56110006631	PemK-like protein; Region: PemK; pfam02452
56110006632	DNA polymerase III subunit delta'; Validated; Region: PRK07399
56110006633	AAA ATPase domain; Region: AAA_16; pfam13191
56110006634	DNA polymerase III subunit delta'; Validated; Region: PRK08485
56110006635	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
56110006636	FAD binding domain; Region: FAD_binding_4; pfam01565
56110006637	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
56110006638	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
56110006639	Cysteine-rich domain; Region: CCG; pfam02754
56110006640	Cysteine-rich domain; Region: CCG; pfam02754
56110006641	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110006642	binding surface
56110006643	TPR repeat; Region: TPR_11; pfam13414
56110006644	TPR motif; other site
56110006645	Protein kinase domain; Region: Pkinase; pfam00069
56110006646	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006647	active site
56110006648	ATP binding site [chemical binding]; other site
56110006649	substrate binding site [chemical binding]; other site
56110006650	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110006651	substrate binding site [chemical binding]; other site
56110006652	activation loop (A-loop); other site
56110006653	activation loop (A-loop); other site
56110006654	AAA ATPase domain; Region: AAA_16; pfam13191
56110006655	Predicted ATPase [General function prediction only]; Region: COG3899
56110006656	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006657	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006658	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006659	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006660	ATP binding site [chemical binding]; other site
56110006661	Mg2+ binding site [ion binding]; other site
56110006662	G-X-G motif; other site
56110006663	Protein kinase domain; Region: Pkinase; pfam00069
56110006664	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006665	active site
56110006666	ATP binding site [chemical binding]; other site
56110006667	substrate binding site [chemical binding]; other site
56110006668	activation loop (A-loop); other site
56110006669	AAA ATPase domain; Region: AAA_16; pfam13191
56110006670	Predicted ATPase [General function prediction only]; Region: COG3899
56110006671	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006672	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006673	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006674	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006675	ATP binding site [chemical binding]; other site
56110006676	Mg2+ binding site [ion binding]; other site
56110006677	G-X-G motif; other site
56110006678	Protein kinase domain; Region: Pkinase; pfam00069
56110006679	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006680	active site
56110006681	ATP binding site [chemical binding]; other site
56110006682	substrate binding site [chemical binding]; other site
56110006683	activation loop (A-loop); other site
56110006684	AAA ATPase domain; Region: AAA_16; pfam13191
56110006685	Predicted ATPase [General function prediction only]; Region: COG3899
56110006686	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006687	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006688	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006689	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006690	ATP binding site [chemical binding]; other site
56110006691	Mg2+ binding site [ion binding]; other site
56110006692	G-X-G motif; other site
56110006693	Protein kinase domain; Region: Pkinase; pfam00069
56110006694	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006695	active site
56110006696	ATP binding site [chemical binding]; other site
56110006697	substrate binding site [chemical binding]; other site
56110006698	activation loop (A-loop); other site
56110006699	AAA ATPase domain; Region: AAA_16; pfam13191
56110006700	Predicted ATPase [General function prediction only]; Region: COG3899
56110006701	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006702	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006703	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006704	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006705	ATP binding site [chemical binding]; other site
56110006706	Mg2+ binding site [ion binding]; other site
56110006707	G-X-G motif; other site
56110006708	Protein kinase domain; Region: Pkinase; pfam00069
56110006709	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006710	active site
56110006711	ATP binding site [chemical binding]; other site
56110006712	substrate binding site [chemical binding]; other site
56110006713	activation loop (A-loop); other site
56110006714	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110006715	AAA ATPase domain; Region: AAA_16; pfam13191
56110006716	Predicted ATPase [General function prediction only]; Region: COG3899
56110006717	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006718	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006719	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006720	dimer interface [polypeptide binding]; other site
56110006721	phosphorylation site [posttranslational modification]
56110006722	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006723	ATP binding site [chemical binding]; other site
56110006724	Mg2+ binding site [ion binding]; other site
56110006725	G-X-G motif; other site
56110006726	Protein kinase domain; Region: Pkinase; pfam00069
56110006727	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006728	active site
56110006729	ATP binding site [chemical binding]; other site
56110006730	substrate binding site [chemical binding]; other site
56110006731	activation loop (A-loop); other site
56110006732	AAA ATPase domain; Region: AAA_16; pfam13191
56110006733	Predicted ATPase [General function prediction only]; Region: COG3899
56110006734	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006735	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006736	PAS domain S-box; Region: sensory_box; TIGR00229
56110006737	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006738	putative active site [active]
56110006739	heme pocket [chemical binding]; other site
56110006740	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006741	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006742	ATP binding site [chemical binding]; other site
56110006743	Mg2+ binding site [ion binding]; other site
56110006744	G-X-G motif; other site
56110006745	Protein kinase domain; Region: Pkinase; pfam00069
56110006746	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006747	active site
56110006748	ATP binding site [chemical binding]; other site
56110006749	substrate binding site [chemical binding]; other site
56110006750	activation loop (A-loop); other site
56110006751	AAA ATPase domain; Region: AAA_16; pfam13191
56110006752	Predicted ATPase [General function prediction only]; Region: COG3899
56110006753	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006754	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006755	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006756	dimer interface [polypeptide binding]; other site
56110006757	phosphorylation site [posttranslational modification]
56110006758	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006759	ATP binding site [chemical binding]; other site
56110006760	Mg2+ binding site [ion binding]; other site
56110006761	G-X-G motif; other site
56110006762	Protein kinase domain; Region: Pkinase; pfam00069
56110006763	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006764	active site
56110006765	ATP binding site [chemical binding]; other site
56110006766	substrate binding site [chemical binding]; other site
56110006767	activation loop (A-loop); other site
56110006768	AAA ATPase domain; Region: AAA_16; pfam13191
56110006769	Predicted ATPase [General function prediction only]; Region: COG3899
56110006770	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006771	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006772	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006773	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006774	ATP binding site [chemical binding]; other site
56110006775	Mg2+ binding site [ion binding]; other site
56110006776	G-X-G motif; other site
56110006777	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110006778	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006779	active site
56110006780	ATP binding site [chemical binding]; other site
56110006781	substrate binding site [chemical binding]; other site
56110006782	activation loop (A-loop); other site
56110006783	AAA ATPase domain; Region: AAA_16; pfam13191
56110006784	Predicted ATPase [General function prediction only]; Region: COG3899
56110006785	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006786	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006787	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006788	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006789	ATP binding site [chemical binding]; other site
56110006790	Mg2+ binding site [ion binding]; other site
56110006791	G-X-G motif; other site
56110006792	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02705
56110006793	XdhC Rossmann domain; Region: XdhC_C; pfam13478
56110006794	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
56110006795	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
56110006796	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
56110006797	CHASE domain; Region: CHASE; pfam03924
56110006798	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110006799	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110006800	dimer interface [polypeptide binding]; other site
56110006801	phosphorylation site [posttranslational modification]
56110006802	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006803	ATP binding site [chemical binding]; other site
56110006804	Mg2+ binding site [ion binding]; other site
56110006805	G-X-G motif; other site
56110006806	TPR repeat; Region: TPR_11; pfam13414
56110006807	TPR repeat; Region: TPR_11; pfam13414
56110006808	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110006809	binding surface
56110006810	TPR motif; other site
56110006811	TPR repeat; Region: TPR_11; pfam13414
56110006812	TPR repeat; Region: TPR_11; pfam13414
56110006813	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110006814	binding surface
56110006815	TPR motif; other site
56110006816	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110006817	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
56110006818	elongation factor G; Reviewed; Region: PRK12740
56110006819	G1 box; other site
56110006820	putative GEF interaction site [polypeptide binding]; other site
56110006821	GTP/Mg2+ binding site [chemical binding]; other site
56110006822	Switch I region; other site
56110006823	G2 box; other site
56110006824	G3 box; other site
56110006825	Switch II region; other site
56110006826	G4 box; other site
56110006827	G5 box; other site
56110006828	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
56110006829	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
56110006830	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
56110006831	CHASE3 domain; Region: CHASE3; cl05000
56110006832	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110006833	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110006834	dimer interface [polypeptide binding]; other site
56110006835	putative CheW interface [polypeptide binding]; other site
56110006836	CHASE3 domain; Region: CHASE3; pfam05227
56110006837	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110006838	putative CheW interface [polypeptide binding]; other site
56110006839	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110006840	putative binding surface; other site
56110006841	active site
56110006842	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
56110006843	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
56110006844	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006845	ATP binding site [chemical binding]; other site
56110006846	Mg2+ binding site [ion binding]; other site
56110006847	G-X-G motif; other site
56110006848	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
56110006849	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110006850	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006851	active site
56110006852	phosphorylation site [posttranslational modification]
56110006853	intermolecular recognition site; other site
56110006854	dimerization interface [polypeptide binding]; other site
56110006855	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
56110006856	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006857	active site
56110006858	phosphorylation site [posttranslational modification]
56110006859	intermolecular recognition site; other site
56110006860	dimerization interface [polypeptide binding]; other site
56110006861	CheB methylesterase; Region: CheB_methylest; pfam01339
56110006862	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
56110006863	putative active site [active]
56110006864	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110006865	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110006866	active site
56110006867	ATP binding site [chemical binding]; other site
56110006868	substrate binding site [chemical binding]; other site
56110006869	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110006870	substrate binding site [chemical binding]; other site
56110006871	activation loop (A-loop); other site
56110006872	activation loop (A-loop); other site
56110006873	AAA ATPase domain; Region: AAA_16; pfam13191
56110006874	Predicted ATPase [General function prediction only]; Region: COG3899
56110006875	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110006876	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006877	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110006878	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110006879	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110006880	putative active site [active]
56110006881	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
56110006882	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110006883	putative binding surface; other site
56110006884	active site
56110006885	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
56110006886	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
56110006887	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110006888	ATP binding site [chemical binding]; other site
56110006889	Mg2+ binding site [ion binding]; other site
56110006890	G-X-G motif; other site
56110006891	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
56110006892	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006893	Response regulator receiver domain; Region: Response_reg; pfam00072
56110006894	active site
56110006895	phosphorylation site [posttranslational modification]
56110006896	intermolecular recognition site; other site
56110006897	dimerization interface [polypeptide binding]; other site
56110006898	PAS domain S-box; Region: sensory_box; TIGR00229
56110006899	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006900	putative active site [active]
56110006901	heme pocket [chemical binding]; other site
56110006902	PAS domain S-box; Region: sensory_box; TIGR00229
56110006903	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006904	putative active site [active]
56110006905	heme pocket [chemical binding]; other site
56110006906	PAS fold; Region: PAS_4; pfam08448
56110006907	PAS domain S-box; Region: sensory_box; TIGR00229
56110006908	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006909	putative active site [active]
56110006910	heme pocket [chemical binding]; other site
56110006911	PAS domain S-box; Region: sensory_box; TIGR00229
56110006912	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006913	putative active site [active]
56110006914	heme pocket [chemical binding]; other site
56110006915	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006916	PAS domain; Region: PAS_9; pfam13426
56110006917	putative active site [active]
56110006918	heme pocket [chemical binding]; other site
56110006919	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110006920	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110006921	dimer interface [polypeptide binding]; other site
56110006922	putative CheW interface [polypeptide binding]; other site
56110006923	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006924	PAS domain; Region: PAS_9; pfam13426
56110006925	putative active site [active]
56110006926	heme pocket [chemical binding]; other site
56110006927	PAS fold; Region: PAS_4; pfam08448
56110006928	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006929	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110006930	putative active site [active]
56110006931	heme pocket [chemical binding]; other site
56110006932	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110006933	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006934	putative active site [active]
56110006935	heme pocket [chemical binding]; other site
56110006936	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006937	putative active site [active]
56110006938	heme pocket [chemical binding]; other site
56110006939	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110006940	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110006941	dimer interface [polypeptide binding]; other site
56110006942	putative CheW interface [polypeptide binding]; other site
56110006943	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
56110006944	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
56110006945	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
56110006946	AAA ATPase domain; Region: AAA_16; pfam13191
56110006947	Response regulator receiver domain; Region: Response_reg; pfam00072
56110006948	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110006949	active site
56110006950	phosphorylation site [posttranslational modification]
56110006951	intermolecular recognition site; other site
56110006952	dimerization interface [polypeptide binding]; other site
56110006953	thiamine biosynthesis protein ThiC; Provisional; Region: PRK13352
56110006954	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
56110006955	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
56110006956	Methyltransferase domain; Region: Methyltransf_26; pfam13659
56110006957	probable polyamine oxidase; Region: PLN02268
56110006958	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110006959	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
56110006960	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110006961	GAF domain; Region: GAF; pfam01590
56110006962	PAS fold; Region: PAS_4; pfam08448
56110006963	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110006964	putative active site [active]
56110006965	heme pocket [chemical binding]; other site
56110006966	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110006967	cyclase homology domain; Region: CHD; cd07302
56110006968	nucleotidyl binding site; other site
56110006969	metal binding site [ion binding]; metal-binding site
56110006970	dimer interface [polypeptide binding]; other site
56110006971	Predicted aspartyl protease [Posttranslational modification, protein turnover, chaperones]; Region: COG5550; cl17622
56110006972	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
56110006973	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
56110006974	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
56110006975	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110006976	active site
56110006977	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110006978	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110006979	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
56110006980	putative active site [active]
56110006981	putative NTP binding site [chemical binding]; other site
56110006982	putative nucleic acid binding site [nucleotide binding]; other site
56110006983	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110006984	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110006985	active site
56110006986	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
56110006987	Domain of unknown function DUF21; Region: DUF21; pfam01595
56110006988	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
56110006989	Transporter associated domain; Region: CorC_HlyC; smart01091
56110006990	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
56110006991	Ligand Binding Site [chemical binding]; other site
56110006992	Transposase domain (DUF772); Region: DUF772; pfam05598
56110006993	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110006994	Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169
56110006995	Predicted membrane protein [Function unknown]; Region: COG2119
56110006996	Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169
56110006997	Flagellin N-methylase; Region: FliB; pfam03692
56110006998	hypothetical protein; Provisional; Region: PRK13686
56110006999	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007000	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007001	active site
56110007002	phosphorylation site [posttranslational modification]
56110007003	intermolecular recognition site; other site
56110007004	dimerization interface [polypeptide binding]; other site
56110007005	PAS fold; Region: PAS; pfam00989
56110007006	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007007	putative active site [active]
56110007008	heme pocket [chemical binding]; other site
56110007009	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110007010	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
56110007011	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110007012	non-specific DNA interactions [nucleotide binding]; other site
56110007013	DNA binding site [nucleotide binding]
56110007014	sequence specific DNA binding site [nucleotide binding]; other site
56110007015	putative cAMP binding site [chemical binding]; other site
56110007016	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
56110007017	DHH family; Region: DHH; pfam01368
56110007018	DHHA1 domain; Region: DHHA1; pfam02272
56110007019	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110007020	Right handed beta helix region; Region: Beta_helix; pfam13229
56110007021	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
56110007022	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110007023	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
56110007024	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110007025	Phycobilisome protein; Region: Phycobilisome; cl08227
56110007026	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
56110007027	23S rRNA (uracil-5-)-methyltransferase RumA; Region: rumA; TIGR00479
56110007028	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110007029	S-adenosylmethionine binding site [chemical binding]; other site
56110007030	Uncharacterized conserved protein [Function unknown]; Region: COG3339
56110007031	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
56110007032	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
56110007033	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
56110007034	trimer interface [polypeptide binding]; other site
56110007035	active site
56110007036	UDP-GlcNAc binding site [chemical binding]; other site
56110007037	lipid binding site [chemical binding]; lipid-binding site
56110007038	AbrB-like transcriptional regulator; Region: AbrB-like; pfam14250
56110007039	mce related protein; Region: MCE; pfam02470
56110007040	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
56110007041	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
56110007042	Walker A/P-loop; other site
56110007043	ATP binding site [chemical binding]; other site
56110007044	Q-loop/lid; other site
56110007045	ABC transporter signature motif; other site
56110007046	Walker B; other site
56110007047	D-loop; other site
56110007048	H-loop/switch region; other site
56110007049	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
56110007050	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
56110007051	putative substrate binding pocket [chemical binding]; other site
56110007052	dimer interface [polypeptide binding]; other site
56110007053	phosphate binding site [ion binding]; other site
56110007054	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
56110007055	dihydroorotase; Provisional; Region: PRK07575
56110007056	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
56110007057	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
56110007058	active site
56110007059	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
56110007060	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
56110007061	Catalytic site [active]
56110007062	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110007063	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007064	ATP binding site [chemical binding]; other site
56110007065	G-X-G motif; other site
56110007066	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007067	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110007068	putative active site [active]
56110007069	heme pocket [chemical binding]; other site
56110007070	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110007071	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007072	putative active site [active]
56110007073	heme pocket [chemical binding]; other site
56110007074	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007075	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110007076	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110007077	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110007078	metal binding site [ion binding]; metal-binding site
56110007079	active site
56110007080	I-site; other site
56110007081	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
56110007082	ABC1 family; Region: ABC1; cl17513
56110007083	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
56110007084	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
56110007085	inhibitor-cofactor binding pocket; inhibition site
56110007086	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110007087	catalytic residue [active]
56110007088	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
56110007089	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
56110007090	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
56110007091	probable non-F420 flavinoid oxidoreductase; Region: flavin_revert; TIGR03885
56110007092	Glycoside hydrolase family 15, N-terminal domain; Region: GH15_N; cd07430
56110007093	Domain interface; other site
56110007094	glucan 1,4-alpha-glucosidase; Region: glucan_glucosid; TIGR01535
56110007095	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
56110007096	Succinyl-CoA synthetase, beta subunit [Energy production and conversion]; Region: SucC; COG0045
56110007097	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
56110007098	CoA-ligase; Region: Ligase_CoA; pfam00549
56110007099	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
56110007100	CoA binding domain; Region: CoA_binding; smart00881
56110007101	CoA-ligase; Region: Ligase_CoA; pfam00549
56110007102	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG2607
56110007103	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110007104	Walker A motif; other site
56110007105	ATP binding site [chemical binding]; other site
56110007106	Walker B motif; other site
56110007107	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
56110007108	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
56110007109	Predicted integral membrane protein [Function unknown]; Region: COG5637
56110007110	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_8; cd07817
56110007111	putative hydrophobic ligand binding site [chemical binding]; other site
56110007112	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
56110007113	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
56110007114	NAD binding site [chemical binding]; other site
56110007115	catalytic Zn binding site [ion binding]; other site
56110007116	structural Zn binding site [ion binding]; other site
56110007117	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
56110007118	RimM N-terminal domain; Region: RimM; pfam01782
56110007119	PRC-barrel domain; Region: PRC; pfam05239
56110007120	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110007121	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110007122	active site
56110007123	ATP binding site [chemical binding]; other site
56110007124	substrate binding site [chemical binding]; other site
56110007125	activation loop (A-loop); other site
56110007126	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110007127	AAA ATPase domain; Region: AAA_16; pfam13191
56110007128	Predicted ATPase [General function prediction only]; Region: COG3899
56110007129	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007130	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110007131	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110007132	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110007133	dimer interface [polypeptide binding]; other site
56110007134	phosphorylation site [posttranslational modification]
56110007135	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007136	ATP binding site [chemical binding]; other site
56110007137	Mg2+ binding site [ion binding]; other site
56110007138	G-X-G motif; other site
56110007139	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110007140	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007141	active site
56110007142	phosphorylation site [posttranslational modification]
56110007143	intermolecular recognition site; other site
56110007144	dimerization interface [polypeptide binding]; other site
56110007145	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007146	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007147	active site
56110007148	phosphorylation site [posttranslational modification]
56110007149	intermolecular recognition site; other site
56110007150	dimerization interface [polypeptide binding]; other site
56110007151	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110007152	dimer interface [polypeptide binding]; other site
56110007153	phosphorylation site [posttranslational modification]
56110007154	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007155	ATP binding site [chemical binding]; other site
56110007156	Mg2+ binding site [ion binding]; other site
56110007157	G-X-G motif; other site
56110007158	Mannosyltransferase putative; Region: Mannosyl_trans3; pfam11051
56110007159	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110007160	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
56110007161	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
56110007162	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
56110007163	NAD(P) binding site [chemical binding]; other site
56110007164	ferrochelatase; Reviewed; Region: hemH; PRK00035
56110007165	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
56110007166	active site
56110007167	C-terminal domain interface [polypeptide binding]; other site
56110007168	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
56110007169	active site
56110007170	N-terminal domain interface [polypeptide binding]; other site
56110007171	Chlorophyll A-B binding protein; Region: Chloroa_b-bind; pfam00504
56110007172	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110007173	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110007174	S-adenosylmethionine binding site [chemical binding]; other site
56110007175	Protein of unknown function (DUF3365); Region: DUF3365; pfam11845
56110007176	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110007177	cyclase homology domain; Region: CHD; cd07302
56110007178	nucleotidyl binding site; other site
56110007179	metal binding site [ion binding]; metal-binding site
56110007180	dimer interface [polypeptide binding]; other site
56110007181	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
56110007182	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
56110007183	motif 1; other site
56110007184	active site
56110007185	motif 2; other site
56110007186	motif 3; other site
56110007187	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
56110007188	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
56110007189	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110007190	cofactor binding site; other site
56110007191	DNA binding site [nucleotide binding]
56110007192	substrate interaction site [chemical binding]; other site
56110007193	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110007194	active site
56110007195	NTP binding site [chemical binding]; other site
56110007196	metal binding triad [ion binding]; metal-binding site
56110007197	antibiotic binding site [chemical binding]; other site
56110007198	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
56110007199	Phosphotransferase enzyme family; Region: APH; pfam01636
56110007200	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
56110007201	active site
56110007202	ATP binding site [chemical binding]; other site
56110007203	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
56110007204	substrate binding site [chemical binding]; other site
56110007205	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
56110007206	tartrate dehydrogenase; Region: TTC; TIGR02089
56110007207	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
56110007208	active site
56110007209	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
56110007210	Peptidase family M9 N-terminal; Region: Peptidase_M9_N; pfam08453
56110007211	Transcriptional regulator PadR-like family; Region: PadR; cl17335
56110007212	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
56110007213	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
56110007214	active site
56110007215	substrate binding site [chemical binding]; other site
56110007216	catalytic site [active]
56110007217	DEAD-like helicases superfamily; Region: DEXDc; smart00487
56110007218	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110007219	ATP binding site [chemical binding]; other site
56110007220	putative Mg++ binding site [ion binding]; other site
56110007221	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110007222	nucleotide binding region [chemical binding]; other site
56110007223	ATP-binding site [chemical binding]; other site
56110007224	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
56110007225	Part of AAA domain; Region: AAA_19; pfam13245
56110007226	Family description; Region: UvrD_C_2; pfam13538
56110007227	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
56110007228	hypothetical protein; Reviewed; Region: PRK09588
56110007229	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
56110007230	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
56110007231	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
56110007232	Archease protein family (MTH1598/TM1083); Region: Archease; pfam01951
56110007233	S-layer homology domain; Region: SLH; pfam00395
56110007234	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007235	TPR repeat; Region: TPR_11; pfam13414
56110007236	binding surface
56110007237	TPR motif; other site
56110007238	TPR repeat; Region: TPR_11; pfam13414
56110007239	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007240	binding surface
56110007241	TPR motif; other site
56110007242	TPR repeat; Region: TPR_11; pfam13414
56110007243	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110007244	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007245	binding surface
56110007246	TPR motif; other site
56110007247	TPR repeat; Region: TPR_11; pfam13414
56110007248	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007249	binding surface
56110007250	TPR motif; other site
56110007251	TPR repeat; Region: TPR_11; pfam13414
56110007252	TPR repeat; Region: TPR_11; pfam13414
56110007253	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007254	binding surface
56110007255	TPR motif; other site
56110007256	Protein of unknown function (DUF563); Region: DUF563; pfam04577
56110007257	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110007258	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007259	binding surface
56110007260	TPR motif; other site
56110007261	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007262	binding surface
56110007263	TPR motif; other site
56110007264	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007265	binding surface
56110007266	TPR motif; other site
56110007267	Protein of unknown function (DUF563); Region: DUF563; pfam04577
56110007268	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007269	binding surface
56110007270	TPR motif; other site
56110007271	TPR repeat; Region: TPR_11; pfam13414
56110007272	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007273	binding surface
56110007274	TPR motif; other site
56110007275	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007276	binding surface
56110007277	TPR motif; other site
56110007278	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
56110007279	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110007280	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
56110007281	active site
56110007282	putative homodimer interface [polypeptide binding]; other site
56110007283	SAM binding site [chemical binding]; other site
56110007284	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
56110007285	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110007286	S-adenosylmethionine binding site [chemical binding]; other site
56110007287	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
56110007288	DNA polymerase III subunit delta; Validated; Region: PRK07452
56110007289	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
56110007290	Domain of unknown function (DUF4168); Region: DUF4168; pfam13767
56110007291	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110007292	putative active site [active]
56110007293	photosystem II 47 kDa protein; Region: psbB; CHL00062
56110007294	photosystem II reaction center protein T; Reviewed; Region: psbT; PRK11875
56110007295	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
56110007296	ATP cone domain; Region: ATP-cone; pfam03477
56110007297	30S ribosomal protein S1; Reviewed; Region: PRK07400
56110007298	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
56110007299	RNA binding site [nucleotide binding]; other site
56110007300	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
56110007301	RNA binding site [nucleotide binding]; other site
56110007302	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
56110007303	RNA binding site [nucleotide binding]; other site
56110007304	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
56110007305	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110007306	motif II; other site
56110007307	S-adenosylmethionine synthetase; Validated; Region: PRK05250
56110007308	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
56110007309	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
56110007310	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
56110007311	Protein of unknown function (DUF3352); Region: DUF3352; pfam11832
56110007312	Alpha/beta hydrolase of unknown function (DUF1400); Region: DUF1400; pfam07176
56110007313	Alpha/beta hydrolase of unknown function (DUF1400); Region: DUF1400; pfam07176
56110007314	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
56110007315	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
56110007316	metal binding site [ion binding]; metal-binding site
56110007317	dimer interface [polypeptide binding]; other site
56110007318	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
56110007319	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
56110007320	putative active site [active]
56110007321	catalytic site [active]
56110007322	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007323	TPR repeat; Region: TPR_11; pfam13414
56110007324	binding surface
56110007325	TPR motif; other site
56110007326	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007327	binding surface
56110007328	TPR motif; other site
56110007329	TPR repeat; Region: TPR_11; pfam13414
56110007330	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007331	binding surface
56110007332	TPR motif; other site
56110007333	TPR repeat; Region: TPR_11; pfam13414
56110007334	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
56110007335	Domain of unknown function (DUF3368); Region: DUF3368; pfam11848
56110007336	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110007337	Uncharacterized conserved protein [Function unknown]; Region: COG2968
56110007338	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
56110007339	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
56110007340	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
56110007341	ligand binding site [chemical binding]; other site
56110007342	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
56110007343	Part of AAA domain; Region: AAA_19; pfam13245
56110007344	Family description; Region: UvrD_C_2; pfam13538
56110007345	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
56110007346	D-xylulose kinase; Region: XylB; TIGR01312
56110007347	nucleotide binding site [chemical binding]; other site
56110007348	acetyl-CoA synthetase; Provisional; Region: PRK00174
56110007349	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
56110007350	active site
56110007351	CoA binding site [chemical binding]; other site
56110007352	acyl-activating enzyme (AAE) consensus motif; other site
56110007353	AMP binding site [chemical binding]; other site
56110007354	acetate binding site [chemical binding]; other site
56110007355	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
56110007356	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110007357	catalytic loop [active]
56110007358	iron binding site [ion binding]; other site
56110007359	Protein of unknown function (DUF3326); Region: DUF3326; pfam11805
56110007360	CAAX protease self-immunity; Region: Abi; pfam02517
56110007361	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
56110007362	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
56110007363	active site
56110007364	substrate binding site [chemical binding]; other site
56110007365	cosubstrate binding site; other site
56110007366	catalytic site [active]
56110007367	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110007368	putative active site [active]
56110007369	Dynamin family; Region: Dynamin_N; pfam00350
56110007370	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
56110007371	G1 box; other site
56110007372	GTP/Mg2+ binding site [chemical binding]; other site
56110007373	Switch I region; other site
56110007374	G2 box; other site
56110007375	Switch II region; other site
56110007376	G3 box; other site
56110007377	G4 box; other site
56110007378	G5 box; other site
56110007379	Domain of unknown function (DUF697); Region: DUF697; pfam05128
56110007380	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110007381	G3 box; other site
56110007382	Switch II region; other site
56110007383	GTP/Mg2+ binding site [chemical binding]; other site
56110007384	G4 box; other site
56110007385	G5 box; other site
56110007386	Domain of unknown function (DUF697); Region: DUF697; pfam05128
56110007387	Prokaryotic metallothionein; Region: Metallothio_Pro; pfam02069
56110007388	ribosomal protein S4; Reviewed; Region: rps4; CHL00113
56110007389	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
56110007390	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
56110007391	RNA binding surface [nucleotide binding]; other site
56110007392	molybdenum cofactor biosynthesis protein A, bacterial; Region: moaA; TIGR02666
56110007393	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110007394	FeS/SAM binding site; other site
56110007395	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
56110007396	PPOX class probable FMN-dependent enzyme, alr4036 family; Region: PPOX_FMN_cyano; TIGR04026
56110007397	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxase_2; pfam12766
56110007398	GAF domain; Region: GAF; cl17456
56110007399	GAF domain; Region: GAF_2; pfam13185
56110007400	PAS domain S-box; Region: sensory_box; TIGR00229
56110007401	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007402	putative active site [active]
56110007403	heme pocket [chemical binding]; other site
56110007404	PAS domain S-box; Region: sensory_box; TIGR00229
56110007405	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007406	putative active site [active]
56110007407	heme pocket [chemical binding]; other site
56110007408	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007409	GAF domain; Region: GAF; pfam01590
56110007410	PAS domain S-box; Region: sensory_box; TIGR00229
56110007411	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007412	putative active site [active]
56110007413	heme pocket [chemical binding]; other site
56110007414	GAF domain; Region: GAF; cl17456
56110007415	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110007416	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110007417	metal binding site [ion binding]; metal-binding site
56110007418	active site
56110007419	I-site; other site
56110007420	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110007421	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
56110007422	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
56110007423	metal-binding site [ion binding]
56110007424	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
56110007425	Soluble P-type ATPase [General function prediction only]; Region: COG4087
56110007426	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
56110007427	Thioredoxin; Region: Thioredoxin_4; pfam13462
56110007428	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
56110007429	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
56110007430	putative ligand binding site [chemical binding]; other site
56110007431	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110007432	dimerization interface [polypeptide binding]; other site
56110007433	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110007434	dimer interface [polypeptide binding]; other site
56110007435	phosphorylation site [posttranslational modification]
56110007436	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007437	ATP binding site [chemical binding]; other site
56110007438	Mg2+ binding site [ion binding]; other site
56110007439	G-X-G motif; other site
56110007440	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007441	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007442	structural tetrad; other site
56110007443	CsbD-like; Region: CsbD; pfam05532
56110007444	CsbD-like; Region: CsbD; pfam05532
56110007445	excinuclease ABC subunit B; Provisional; Region: PRK05298
56110007446	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110007447	ATP binding site [chemical binding]; other site
56110007448	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110007449	nucleotide binding region [chemical binding]; other site
56110007450	ATP-binding site [chemical binding]; other site
56110007451	Ultra-violet resistance protein B; Region: UvrB; pfam12344
56110007452	Uncharacterized protein conserved in bacteria (DUF2237); Region: DUF2237; pfam09996
56110007453	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110007454	putative active site [active]
56110007455	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; pfam04014
56110007456	Caspase domain; Region: Peptidase_C14; pfam00656
56110007457	AAA ATPase domain; Region: AAA_16; pfam13191
56110007458	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007459	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007460	structural tetrad; other site
56110007461	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007462	structural tetrad; other site
56110007463	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007464	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110007465	TPR repeat; Region: TPR_11; pfam13414
56110007466	Tetratricopeptide repeat; Region: TPR_2; pfam07719
56110007467	TPR repeat; Region: TPR_11; pfam13414
56110007468	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007469	binding surface
56110007470	TPR motif; other site
56110007471	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110007472	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110007473	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110007474	putative active site [active]
56110007475	putative NTP binding site [chemical binding]; other site
56110007476	putative nucleic acid binding site [nucleotide binding]; other site
56110007477	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110007478	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110007479	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110007480	active site
56110007481	Uncharacterized conserved protein [Function unknown]; Region: COG1565
56110007482	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
56110007483	NAD(P)H-quinone oxidoreductase subunit H; Validated; Region: PRK07415
56110007484	MraW methylase family; Region: Methyltransf_5; cl17771
56110007485	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
56110007486	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110007487	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007488	active site
56110007489	phosphorylation site [posttranslational modification]
56110007490	intermolecular recognition site; other site
56110007491	dimerization interface [polypeptide binding]; other site
56110007492	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007493	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110007494	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110007495	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110007496	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
56110007497	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
56110007498	Mg2+ binding site [ion binding]; other site
56110007499	G-X-G motif; other site
56110007500	SnoaL-like domain; Region: SnoaL_2; pfam12680
56110007501	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007502	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007503	structural tetrad; other site
56110007504	Transposase domain (DUF772); Region: DUF772; pfam05598
56110007505	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
56110007506	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110007507	cofactor binding site; other site
56110007508	DNA binding site [nucleotide binding]
56110007509	substrate interaction site [chemical binding]; other site
56110007510	ICEA Protein; Region: ICEA; pfam05315
56110007511	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110007512	non-specific DNA binding site [nucleotide binding]; other site
56110007513	salt bridge; other site
56110007514	sequence-specific DNA binding site [nucleotide binding]; other site
56110007515	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110007516	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110007517	active site
56110007518	ATP binding site [chemical binding]; other site
56110007519	substrate binding site [chemical binding]; other site
56110007520	activation loop (A-loop); other site
56110007521	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007522	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007523	structural tetrad; other site
56110007524	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
56110007525	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007526	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007527	active site
56110007528	phosphorylation site [posttranslational modification]
56110007529	intermolecular recognition site; other site
56110007530	dimerization interface [polypeptide binding]; other site
56110007531	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110007532	DNA binding residues [nucleotide binding]
56110007533	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110007534	FOG: CBS domain [General function prediction only]; Region: COG0517
56110007535	FOG: CBS domain [General function prediction only]; Region: COG0517
56110007536	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with a PAS domain, a GGDEF (DiGuanylate-Cyclase (DGC) domain, and a DUF1 domain downstream. PAS domains have been found to bind ligands, and to act...; Region: CBS_pair_PAS_GGDEF_DUF1_assoc; cd04611
56110007537	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007538	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110007539	PAS domain S-box; Region: sensory_box; TIGR00229
56110007540	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007541	putative active site [active]
56110007542	heme pocket [chemical binding]; other site
56110007543	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007544	PAS fold; Region: PAS_3; pfam08447
56110007545	putative active site [active]
56110007546	heme pocket [chemical binding]; other site
56110007547	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007548	PAS domain; Region: PAS_9; pfam13426
56110007549	putative active site [active]
56110007550	heme pocket [chemical binding]; other site
56110007551	PAS domain S-box; Region: sensory_box; TIGR00229
56110007552	PAS domain; Region: PAS_8; pfam13188
56110007553	PAS domain S-box; Region: sensory_box; TIGR00229
56110007554	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007555	putative active site [active]
56110007556	heme pocket [chemical binding]; other site
56110007557	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007558	PAS domain; Region: PAS_9; pfam13426
56110007559	putative active site [active]
56110007560	heme pocket [chemical binding]; other site
56110007561	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
56110007562	Histidine kinase; Region: HisKA_2; pfam07568
56110007563	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007564	ATP binding site [chemical binding]; other site
56110007565	Mg2+ binding site [ion binding]; other site
56110007566	G-X-G motif; other site
56110007567	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110007568	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007569	active site
56110007570	phosphorylation site [posttranslational modification]
56110007571	intermolecular recognition site; other site
56110007572	dimerization interface [polypeptide binding]; other site
56110007573	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110007574	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110007575	dimer interface [polypeptide binding]; other site
56110007576	phosphorylation site [posttranslational modification]
56110007577	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007578	ATP binding site [chemical binding]; other site
56110007579	Mg2+ binding site [ion binding]; other site
56110007580	G-X-G motif; other site
56110007581	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007582	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007583	active site
56110007584	phosphorylation site [posttranslational modification]
56110007585	intermolecular recognition site; other site
56110007586	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110007587	dimerization interface [polypeptide binding]; other site
56110007588	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110007589	dimer interface [polypeptide binding]; other site
56110007590	phosphorylation site [posttranslational modification]
56110007591	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007592	ATP binding site [chemical binding]; other site
56110007593	Mg2+ binding site [ion binding]; other site
56110007594	G-X-G motif; other site
56110007595	Hypothetical chloroplast protein Ycf34; Region: Ycf34; pfam10718
56110007596	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
56110007597	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
56110007598	active site
56110007599	NTP binding site [chemical binding]; other site
56110007600	metal binding triad [ion binding]; metal-binding site
56110007601	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
56110007602	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
56110007603	CHAT domain; Region: CHAT; pfam12770
56110007604	AAA ATPase domain; Region: AAA_16; pfam13191
56110007605	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007606	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007607	structural tetrad; other site
56110007608	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007609	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007610	structural tetrad; other site
56110007611	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110007612	Protein kinase domain; Region: Pkinase; pfam00069
56110007613	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110007614	active site
56110007615	ATP binding site [chemical binding]; other site
56110007616	substrate binding site [chemical binding]; other site
56110007617	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110007618	substrate binding site [chemical binding]; other site
56110007619	activation loop (A-loop); other site
56110007620	activation loop (A-loop); other site
56110007621	AAA ATPase domain; Region: AAA_16; pfam13191
56110007622	Predicted ATPase [General function prediction only]; Region: COG3899
56110007623	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007624	GAF domain; Region: GAF; pfam01590
56110007625	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110007626	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110007627	Protein kinase domain; Region: Pkinase; pfam00069
56110007628	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110007629	active site
56110007630	ATP binding site [chemical binding]; other site
56110007631	substrate binding site [chemical binding]; other site
56110007632	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110007633	substrate binding site [chemical binding]; other site
56110007634	activation loop (A-loop); other site
56110007635	activation loop (A-loop); other site
56110007636	AAA ATPase domain; Region: AAA_16; pfam13191
56110007637	Predicted ATPase [General function prediction only]; Region: COG3899
56110007638	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007639	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110007640	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110007641	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110007642	Protein kinase domain; Region: Pkinase; pfam00069
56110007643	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110007644	active site
56110007645	ATP binding site [chemical binding]; other site
56110007646	substrate binding site [chemical binding]; other site
56110007647	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110007648	substrate binding site [chemical binding]; other site
56110007649	activation loop (A-loop); other site
56110007650	activation loop (A-loop); other site
56110007651	AAA ATPase domain; Region: AAA_16; pfam13191
56110007652	Predicted ATPase [General function prediction only]; Region: COG3899
56110007653	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110007654	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110007655	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110007656	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110007657	Catalase-like heme-binding proteins similar to the uncharacterized y4iL; Region: y4iL_like; cd08152
56110007658	putative heme binding pocket [chemical binding]; other site
56110007659	CHAT domain; Region: CHAT; cl17868
56110007660	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
56110007661	Walker A/P-loop; other site
56110007662	ATP binding site [chemical binding]; other site
56110007663	Q-loop/lid; other site
56110007664	Walker B; other site
56110007665	D-loop; other site
56110007666	WD40 repeats; Region: WD40; smart00320
56110007667	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007668	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007669	structural tetrad; other site
56110007670	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007671	structural tetrad; other site
56110007672	CHAT domain; Region: CHAT; pfam12770
56110007673	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
56110007674	Walker A/P-loop; other site
56110007675	ATP binding site [chemical binding]; other site
56110007676	Q-loop/lid; other site
56110007677	Walker B; other site
56110007678	D-loop; other site
56110007679	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110007680	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007681	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007682	structural tetrad; other site
56110007683	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007684	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007685	structural tetrad; other site
56110007686	Lipoxygenase; Region: Lipoxygenase; pfam00305
56110007687	Predicted NAD/FAD-dependent oxidoreductase [General function prediction only]; Region: COG3380
56110007688	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110007689	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
56110007690	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
56110007691	O-Antigen ligase; Region: Wzy_C; pfam04932
56110007692	Transposase domain (DUF772); Region: DUF772; pfam05598
56110007693	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110007694	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110007695	putative active site [active]
56110007696	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007697	binding surface
56110007698	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110007699	TPR motif; other site
56110007700	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110007701	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110007702	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110007703	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110007704	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110007705	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110007706	CHASE2 domain; Region: CHASE2; pfam05226
56110007707	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007708	PAS domain; Region: PAS_9; pfam13426
56110007709	putative active site [active]
56110007710	heme pocket [chemical binding]; other site
56110007711	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110007712	cyclase homology domain; Region: CHD; cd07302
56110007713	nucleotidyl binding site; other site
56110007714	metal binding site [ion binding]; metal-binding site
56110007715	dimer interface [polypeptide binding]; other site
56110007716	TPR repeat; Region: TPR_11; pfam13414
56110007717	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3322
56110007718	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110007719	dimerization interface [polypeptide binding]; other site
56110007720	Heme NO binding associated; Region: HNOBA; pfam07701
56110007721	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110007722	cyclase homology domain; Region: CHD; cd07302
56110007723	nucleotidyl binding site; other site
56110007724	metal binding site [ion binding]; metal-binding site
56110007725	dimer interface [polypeptide binding]; other site
56110007726	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
56110007727	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
56110007728	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110007729	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007730	putative active site [active]
56110007731	heme pocket [chemical binding]; other site
56110007732	PAS domain S-box; Region: sensory_box; TIGR00229
56110007733	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007734	putative active site [active]
56110007735	heme pocket [chemical binding]; other site
56110007736	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110007737	cyclase homology domain; Region: CHD; cd07302
56110007738	nucleotidyl binding site; other site
56110007739	metal binding site [ion binding]; metal-binding site
56110007740	dimer interface [polypeptide binding]; other site
56110007741	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110007742	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007743	putative active site [active]
56110007744	heme pocket [chemical binding]; other site
56110007745	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110007746	dimer interface [polypeptide binding]; other site
56110007747	phosphorylation site [posttranslational modification]
56110007748	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007749	ATP binding site [chemical binding]; other site
56110007750	Mg2+ binding site [ion binding]; other site
56110007751	G-X-G motif; other site
56110007752	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110007753	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007754	active site
56110007755	phosphorylation site [posttranslational modification]
56110007756	intermolecular recognition site; other site
56110007757	dimerization interface [polypeptide binding]; other site
56110007758	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007759	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007760	active site
56110007761	phosphorylation site [posttranslational modification]
56110007762	intermolecular recognition site; other site
56110007763	dimerization interface [polypeptide binding]; other site
56110007764	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110007765	putative binding surface; other site
56110007766	active site
56110007767	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007768	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007769	active site
56110007770	phosphorylation site [posttranslational modification]
56110007771	intermolecular recognition site; other site
56110007772	dimerization interface [polypeptide binding]; other site
56110007773	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110007774	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110007775	metal binding site [ion binding]; metal-binding site
56110007776	active site
56110007777	I-site; other site
56110007778	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110007779	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007780	PAS domain; Region: PAS_9; pfam13426
56110007781	putative active site [active]
56110007782	heme pocket [chemical binding]; other site
56110007783	PAS fold; Region: PAS_4; pfam08448
56110007784	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007785	putative active site [active]
56110007786	heme pocket [chemical binding]; other site
56110007787	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110007788	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007789	PAS fold; Region: PAS_3; pfam08447
56110007790	putative active site [active]
56110007791	heme pocket [chemical binding]; other site
56110007792	PAS domain S-box; Region: sensory_box; TIGR00229
56110007793	PAS domain S-box; Region: sensory_box; TIGR00229
56110007794	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110007795	putative active site [active]
56110007796	heme pocket [chemical binding]; other site
56110007797	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110007798	dimer interface [polypeptide binding]; other site
56110007799	phosphorylation site [posttranslational modification]
56110007800	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007801	ATP binding site [chemical binding]; other site
56110007802	Mg2+ binding site [ion binding]; other site
56110007803	G-X-G motif; other site
56110007804	cheY-homologous receiver domain; Region: REC; smart00448
56110007805	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007806	phosphorylation site [posttranslational modification]
56110007807	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007808	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007809	active site
56110007810	phosphorylation site [posttranslational modification]
56110007811	intermolecular recognition site; other site
56110007812	dimerization interface [polypeptide binding]; other site
56110007813	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110007814	putative binding surface; other site
56110007815	active site
56110007816	Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases); Region: Rab; cd00154
56110007817	Rab subfamily motif 1 (RabSF1); other site
56110007818	G1 box; other site
56110007819	GTP/Mg2+ binding site [chemical binding]; other site
56110007820	Rab subfamily motif 2 (RabSF2); other site
56110007821	Switch I region; other site
56110007822	G2 box; other site
56110007823	effector interaction site; other site
56110007824	GDI interaction site; other site
56110007825	Rab family motif 1 (RabF1); other site
56110007826	GEF interaction site [polypeptide binding]; other site
56110007827	Rab family motif 2 (RabF2); other site
56110007828	G3 box; other site
56110007829	Switch II region; other site
56110007830	Rab family motif 3 (RabF3); other site
56110007831	Rab family motif 4 (RabF4); other site
56110007832	Rab family motif 5 (RabF5); other site
56110007833	Rab subfamily motif 3 (RabSF3); other site
56110007834	G4 box; other site
56110007835	G5 box; other site
56110007836	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
56110007837	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
56110007838	ligand binding site [chemical binding]; other site
56110007839	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
56110007840	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
56110007841	GatB domain; Region: GatB_Yqey; smart00845
56110007842	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
56110007843	heterotetramer interface [polypeptide binding]; other site
56110007844	active site pocket [active]
56110007845	cleavage site
56110007846	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
56110007847	active site
56110007848	catalytic triad [active]
56110007849	oxyanion hole [active]
56110007850	photosystem I P700 chlorophyll a apoprotein A2; Provisional; Region: psaB; PRK13199
56110007851	photosystem I reaction center subunit VIII; Reviewed; Region: psaI; PRK11877
56110007852	photosystem I reaction center protein subunit XI; Provisional; Region: PRK00704
56110007853	glutathione reductase; Validated; Region: PRK06116
56110007854	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110007855	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
56110007856	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007857	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007858	active site
56110007859	phosphorylation site [posttranslational modification]
56110007860	intermolecular recognition site; other site
56110007861	dimerization interface [polypeptide binding]; other site
56110007862	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
56110007863	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
56110007864	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110007865	putative binding surface; other site
56110007866	active site
56110007867	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
56110007868	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110007869	ATP binding site [chemical binding]; other site
56110007870	Mg2+ binding site [ion binding]; other site
56110007871	G-X-G motif; other site
56110007872	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
56110007873	Response regulator receiver domain; Region: Response_reg; pfam00072
56110007874	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110007875	active site
56110007876	phosphorylation site [posttranslational modification]
56110007877	intermolecular recognition site; other site
56110007878	dimerization interface [polypeptide binding]; other site
56110007879	Uncharacterized conserved protein [Function unknown]; Region: COG3379
56110007880	Uncharacterized conserved protein [Function unknown]; Region: COG3379
56110007881	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110007882	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110007883	active site
56110007884	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110007885	putative active site [active]
56110007886	YcfA-like protein; Region: YcfA; pfam07927
56110007887	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
56110007888	Uncharacterized conserved protein [Function unknown]; Region: COG3791
56110007889	Maf-like protein; Region: Maf; pfam02545
56110007890	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
56110007891	active site
56110007892	dimer interface [polypeptide binding]; other site
56110007893	PsbP; Region: PsbP; pfam01789
56110007894	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
56110007895	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
56110007896	ATP-grasp domain; Region: ATP-grasp; pfam02222
56110007897	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
56110007898	Double zinc ribbon; Region: DZR; pfam12773
56110007899	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110007900	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110007901	active site
56110007902	ATP binding site [chemical binding]; other site
56110007903	substrate binding site [chemical binding]; other site
56110007904	activation loop (A-loop); other site
56110007905	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007906	TPR motif; other site
56110007907	binding surface
56110007908	TPR repeat; Region: TPR_11; pfam13414
56110007909	TPR repeat; Region: TPR_11; pfam13414
56110007910	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110007911	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110007912	structural tetrad; other site
56110007913	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110007914	putative active site [active]
56110007915	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
56110007916	Glycoprotease family; Region: Peptidase_M22; pfam00814
56110007917	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110007918	active site
56110007919	Thf1-like protein; Reviewed; Region: PRK13266
56110007920	photosystem II biogenesis protein Psp29; Region: PS_II_psb29; TIGR03060
56110007921	CpeT/CpcT family (DUF1001); Region: CpeT; pfam06206
56110007922	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110007923	anti sigma factor interaction site; other site
56110007924	regulatory phosphorylation site [posttranslational modification]; other site
56110007925	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
56110007926	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
56110007927	antiporter inner membrane protein; Provisional; Region: PRK11670
56110007928	Domain of unknown function DUF59; Region: DUF59; pfam01883
56110007929	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
56110007930	Walker A motif; other site
56110007931	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
56110007932	Protein of unknown function (DUF3252); Region: DUF3252; pfam11623
56110007933	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
56110007934	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
56110007935	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
56110007936	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cl04270
56110007937	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110007938	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110007939	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110007940	This family is most closely related to the GT1 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II); Region: GT1_ExpE7_like; cd03823
56110007941	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110007942	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110007943	S-adenosylmethionine binding site [chemical binding]; other site
56110007944	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
56110007945	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110007946	active site
56110007947	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
56110007948	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110007949	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110007950	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
56110007951	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110007952	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
56110007953	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
56110007954	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110007955	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
56110007956	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110007957	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110007958	active site
56110007959	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
56110007960	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
56110007961	putative ADP-binding pocket [chemical binding]; other site
56110007962	Putative methyltransferase; Region: Methyltransf_4; cl17290
56110007963	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110007964	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110007965	S-adenosylmethionine binding site [chemical binding]; other site
56110007966	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110007967	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110007968	colanic acid exporter; Provisional; Region: PRK10459
56110007969	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
56110007970	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
56110007971	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
56110007972	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
56110007973	SLBB domain; Region: SLBB; pfam10531
56110007974	Chain length determinant protein; Region: Wzz; pfam02706
56110007975	polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Region: pepcterm_ChnLen; TIGR03007
56110007976	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
56110007977	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
56110007978	Transposase domain (DUF772); Region: DUF772; pfam05598
56110007979	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
56110007980	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
56110007981	RNA binding site [nucleotide binding]; other site
56110007982	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
56110007983	RNA binding site [nucleotide binding]; other site
56110007984	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
56110007985	RNA binding site [nucleotide binding]; other site
56110007986	Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not...; Region: ZnMc_serralysin_like; cd04277
56110007987	active site
56110007988	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
56110007989	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
56110007990	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
56110007991	Predicted transcriptional regulators [Transcription]; Region: COG1725
56110007992	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
56110007993	DNA-binding site [nucleotide binding]; DNA binding site
56110007994	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110007995	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110007996	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110007997	TPR repeat; Region: TPR_11; pfam13414
56110007998	binding surface
56110007999	TPR motif; other site
56110008000	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008001	binding surface
56110008002	TPR repeat; Region: TPR_11; pfam13414
56110008003	TPR motif; other site
56110008004	TPR repeat; Region: TPR_11; pfam13414
56110008005	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110008006	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110008007	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110008008	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110008009	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
56110008010	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
56110008011	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110008012	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
56110008013	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
56110008014	catalytic triad [active]
56110008015	HEAT repeats; Region: HEAT_2; pfam13646
56110008016	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
56110008017	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
56110008018	intersubunit interface [polypeptide binding]; other site
56110008019	active site
56110008020	zinc binding site [ion binding]; other site
56110008021	Na+ binding site [ion binding]; other site
56110008022	Aldose 1-epimerase, similar to Synechocystis Slr1438; Region: Aldose_epim_Slr1438; cd09025
56110008023	active site
56110008024	catalytic residues [active]
56110008025	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
56110008026	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
56110008027	putative active site [active]
56110008028	putative metal binding site [ion binding]; other site
56110008029	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110008030	S-adenosylmethionine binding site [chemical binding]; other site
56110008031	RRXRR protein; Region: RRXRR; pfam14239
56110008032	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110008033	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110008034	active site
56110008035	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
56110008036	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110008037	motif II; other site
56110008038	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110008039	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
56110008040	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
56110008041	substrate binding pocket [chemical binding]; other site
56110008042	membrane-bound complex binding site; other site
56110008043	hinge residues; other site
56110008044	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
56110008045	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
56110008046	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
56110008047	putative dimer interface [polypeptide binding]; other site
56110008048	N-terminal domain interface [polypeptide binding]; other site
56110008049	putative substrate binding pocket (H-site) [chemical binding]; other site
56110008050	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
56110008051	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110008052	dimer interface [polypeptide binding]; other site
56110008053	conserved gate region; other site
56110008054	putative PBP binding loops; other site
56110008055	ABC-ATPase subunit interface; other site
56110008056	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
56110008057	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110008058	dimer interface [polypeptide binding]; other site
56110008059	conserved gate region; other site
56110008060	putative PBP binding loops; other site
56110008061	ABC-ATPase subunit interface; other site
56110008062	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110008063	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110008064	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
56110008065	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
56110008066	Walker A/P-loop; other site
56110008067	ATP binding site [chemical binding]; other site
56110008068	Q-loop/lid; other site
56110008069	ABC transporter signature motif; other site
56110008070	Walker B; other site
56110008071	D-loop; other site
56110008072	H-loop/switch region; other site
56110008073	Uncharacterized conserved protein [Function unknown]; Region: COG4095
56110008074	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110008075	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110008076	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
56110008077	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110008078	FeS/SAM binding site; other site
56110008079	Cysteine-rich CPXCG; Region: Cys_rich_CPXG; pfam14255
56110008080	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
56110008081	putative hydrophobic ligand binding site [chemical binding]; other site
56110008082	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008083	PAS domain; Region: PAS_9; pfam13426
56110008084	putative active site [active]
56110008085	heme pocket [chemical binding]; other site
56110008086	PAS domain; Region: PAS_9; pfam13426
56110008087	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008088	putative active site [active]
56110008089	heme pocket [chemical binding]; other site
56110008090	PAS domain S-box; Region: sensory_box; TIGR00229
56110008091	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008092	putative active site [active]
56110008093	heme pocket [chemical binding]; other site
56110008094	PAS domain S-box; Region: sensory_box; TIGR00229
56110008095	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008096	putative active site [active]
56110008097	heme pocket [chemical binding]; other site
56110008098	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110008099	GAF domain; Region: GAF; pfam01590
56110008100	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110008101	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110008102	dimer interface [polypeptide binding]; other site
56110008103	phosphorylation site [posttranslational modification]
56110008104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110008105	ATP binding site [chemical binding]; other site
56110008106	Mg2+ binding site [ion binding]; other site
56110008107	G-X-G motif; other site
56110008108	ncharacterized protein conserved in bacteria [Function unknown]; Region: SpoIIIAA; COG3854
56110008109	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110008110	Walker A motif; other site
56110008111	ATP binding site [chemical binding]; other site
56110008112	Walker B motif; other site
56110008113	R3H domain of a group of proteins with unknown function, who also contain a AAA-ATPase (AAA) domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is...; Region: R3H_AAA; cd02645
56110008114	RxxxH motif; other site
56110008115	4Fe-4S binding domain; Region: Fer4; pfam00037
56110008116	Iron-Sulfur binding protein C terminal; Region: LdpA_C; pfam12617
56110008117	VWA ORF176 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_ORF176_type; cd01457
56110008118	metal ion-dependent adhesion site (MIDAS); other site
56110008119	VWA ORF176 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_ORF176_type; cd01457
56110008120	metal ion-dependent adhesion site (MIDAS); other site
56110008121	VWA ORF176 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_ORF176_type; cd01457
56110008122	metal ion-dependent adhesion site (MIDAS); other site
56110008123	NADH-quinone oxidoreductase cyanobacterial subunit N; Region: NdhN; pfam11909
56110008124	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
56110008125	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
56110008126	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
56110008127	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
56110008128	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
56110008129	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
56110008130	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
56110008131	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
56110008132	putative translocon binding site; other site
56110008133	protein-rRNA interface [nucleotide binding]; other site
56110008134	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
56110008135	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
56110008136	G-X-X-G motif; other site
56110008137	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
56110008138	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
56110008139	23S rRNA interface [nucleotide binding]; other site
56110008140	5S rRNA interface [nucleotide binding]; other site
56110008141	putative antibiotic binding site [chemical binding]; other site
56110008142	L25 interface [polypeptide binding]; other site
56110008143	L27 interface [polypeptide binding]; other site
56110008144	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
56110008145	putative translocon interaction site; other site
56110008146	23S rRNA interface [nucleotide binding]; other site
56110008147	signal recognition particle (SRP54) interaction site; other site
56110008148	L23 interface [polypeptide binding]; other site
56110008149	trigger factor interaction site; other site
56110008150	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
56110008151	ribosomal protein L14; Region: rpl14; CHL00057
56110008152	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
56110008153	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
56110008154	RNA binding site [nucleotide binding]; other site
56110008155	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
56110008156	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
56110008157	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
56110008158	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
56110008159	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
56110008160	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
56110008161	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
56110008162	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
56110008163	5S rRNA interface [nucleotide binding]; other site
56110008164	L5 interface [polypeptide binding]; other site
56110008165	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
56110008166	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
56110008167	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
56110008168	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
56110008169	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
56110008170	SecY translocase; Region: SecY; pfam00344
56110008171	adenylate kinase; Provisional; Region: adk; PRK02496
56110008172	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
56110008173	AMP-binding site [chemical binding]; other site
56110008174	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
56110008175	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
56110008176	rRNA binding site [nucleotide binding]; other site
56110008177	predicted 30S ribosome binding site; other site
56110008178	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
56110008179	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
56110008180	30S ribosomal protein S13; Region: bact_S13; TIGR03631
56110008181	30S ribosomal protein S11; Validated; Region: PRK05309
56110008182	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
56110008183	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
56110008184	alphaNTD homodimer interface [polypeptide binding]; other site
56110008185	alphaNTD - beta interaction site [polypeptide binding]; other site
56110008186	alphaNTD - beta' interaction site [polypeptide binding]; other site
56110008187	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
56110008188	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
56110008189	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
56110008190	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
56110008191	dimerization interface 3.5A [polypeptide binding]; other site
56110008192	active site
56110008193	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
56110008194	23S rRNA interface [nucleotide binding]; other site
56110008195	L3 interface [polypeptide binding]; other site
56110008196	ribosomal protein S9; Region: rps9; CHL00079
56110008197	ribosomal protein L31; Validated; Region: rpl31; CHL00136
56110008198	peptide chain release factor 1; Validated; Region: prfA; PRK00591
56110008199	This domain is found in peptide chain release factors; Region: PCRF; smart00937
56110008200	RF-1 domain; Region: RF-1; pfam00472
56110008201	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
56110008202	Predicted ATPase [General function prediction only]; Region: COG4637
56110008203	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110008204	Walker A/P-loop; other site
56110008205	ATP binding site [chemical binding]; other site
56110008206	radical SAM/Cys-rich domain protein; Region: rSAM_SeCys; TIGR04167
56110008207	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110008208	FeS/SAM binding site; other site
56110008209	Protein of unknown function (DUF3641); Region: DUF3641; pfam12345
56110008210	Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; Region: PRX_like2; cd02970
56110008211	putative catalytic residues [active]
56110008212	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
56110008213	catalytic residues [active]
56110008214	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
56110008215	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
56110008216	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
56110008217	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110008218	catalytic residues [active]
56110008219	mercuric reductase; Validated; Region: PRK06370
56110008220	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110008221	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
56110008222	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110008223	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110008224	S-adenosylmethionine binding site [chemical binding]; other site
56110008225	Uncharacterized conserved protein [Function unknown]; Region: COG0398
56110008226	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
56110008227	Uncharacterized conserved protein (DUF2267); Region: DUF2267; cl02314
56110008228	light-harvesting-like protein 3; Provisional; Region: PLN00014
56110008229	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110008230	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110008231	Cadherin repeat-like domain; Region: CA_like; cl15786
56110008232	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
56110008233	Ca2+ binding site [ion binding]; other site
56110008234	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
56110008235	Cadherin repeat-like domain; Region: CA_like; cl15786
56110008236	Ca2+ binding site [ion binding]; other site
56110008237	conserved repeat domain; Region: B_ant_repeat; TIGR01451
56110008238	Integrin alpha (beta-propellor repeats); Region: Int_alpha; smart00191
56110008239	Integrin alpha (beta-propellor repeats); Region: Int_alpha; smart00191
56110008240	Integrin alpha (beta-propellor repeats); Region: Int_alpha; smart00191
56110008241	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110008242	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110008243	active site
56110008244	phosphorylation site [posttranslational modification]
56110008245	intermolecular recognition site; other site
56110008246	dimerization interface [polypeptide binding]; other site
56110008247	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110008248	DNA binding site [nucleotide binding]
56110008249	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
56110008250	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110008251	dimer interface [polypeptide binding]; other site
56110008252	phosphorylation site [posttranslational modification]
56110008253	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110008254	ATP binding site [chemical binding]; other site
56110008255	Mg2+ binding site [ion binding]; other site
56110008256	G-X-G motif; other site
56110008257	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only]; Region: COG5553
56110008258	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110008259	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
56110008260	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110008261	anti sigma factor interaction site; other site
56110008262	regulatory phosphorylation site [posttranslational modification]; other site
56110008263	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
56110008264	Bacterial sugar transferase; Region: Bac_transf; pfam02397
56110008265	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
56110008266	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110008267	Mg2+ binding site [ion binding]; other site
56110008268	G-X-G motif; other site
56110008269	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110008270	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008271	putative active site [active]
56110008272	heme pocket [chemical binding]; other site
56110008273	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
56110008274	putative active site [active]
56110008275	heme pocket [chemical binding]; other site
56110008276	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110008277	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110008278	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110008279	anti sigma factor interaction site; other site
56110008280	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
56110008281	regulatory phosphorylation site [posttranslational modification]; other site
56110008282	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110008283	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110008284	active site
56110008285	phosphorylation site [posttranslational modification]
56110008286	intermolecular recognition site; other site
56110008287	dimerization interface [polypeptide binding]; other site
56110008288	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110008289	DNA binding site [nucleotide binding]
56110008290	PBP superfamily domain; Region: PBP_like_2; cl17296
56110008291	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
56110008292	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110008293	dimer interface [polypeptide binding]; other site
56110008294	conserved gate region; other site
56110008295	putative PBP binding loops; other site
56110008296	ABC-ATPase subunit interface; other site
56110008297	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110008298	dimer interface [polypeptide binding]; other site
56110008299	conserved gate region; other site
56110008300	ABC-ATPase subunit interface; other site
56110008301	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
56110008302	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
56110008303	Walker A/P-loop; other site
56110008304	ATP binding site [chemical binding]; other site
56110008305	Q-loop/lid; other site
56110008306	ABC transporter signature motif; other site
56110008307	Walker B; other site
56110008308	D-loop; other site
56110008309	H-loop/switch region; other site
56110008310	Lysyl-tRNA synthetase (class I) [Translation, ribosomal structure and biogenesis]; Region: LysS; COG1384
56110008311	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
56110008312	active site
56110008313	nucleotide binding site [chemical binding]; other site
56110008314	HIGH motif; other site
56110008315	KMSKS motif; other site
56110008316	PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase family, and catalyses the hydrolysis of 3'-phosphoadenosine-5'-phosphate (PAP) to AMP. In Saccharomyces cerevisiae, HAL2 (MET22) is involved in methionine...; Region: PAP_phosphatase; cd01517
56110008317	active site
56110008318	putative lithium-binding site [ion binding]; other site
56110008319	substrate binding site [chemical binding]; other site
56110008320	Peptidase family M48; Region: Peptidase_M48; cl12018
56110008321	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
56110008322	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
56110008323	putative catalytic cysteine [active]
56110008324	M28 Zn-Peptidases; Region: M28_like_1; cd05640
56110008325	Peptidase family M28; Region: Peptidase_M28; pfam04389
56110008326	metal binding site [ion binding]; metal-binding site
56110008327	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
56110008328	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
56110008329	active site
56110008330	nucleophile elbow; other site
56110008331	phosphate transporter ATP-binding protein; Provisional; Region: PRK14243
56110008332	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
56110008333	Walker A/P-loop; other site
56110008334	ATP binding site [chemical binding]; other site
56110008335	Q-loop/lid; other site
56110008336	ABC transporter signature motif; other site
56110008337	Walker B; other site
56110008338	D-loop; other site
56110008339	H-loop/switch region; other site
56110008340	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
56110008341	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110008342	dimer interface [polypeptide binding]; other site
56110008343	conserved gate region; other site
56110008344	putative PBP binding loops; other site
56110008345	ABC-ATPase subunit interface; other site
56110008346	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
56110008347	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110008348	dimer interface [polypeptide binding]; other site
56110008349	conserved gate region; other site
56110008350	putative PBP binding loops; other site
56110008351	ABC-ATPase subunit interface; other site
56110008352	phosphate ABC transporter, phosphate-binding protein; Region: 3a0107s03; TIGR00975
56110008353	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
56110008354	Low molecular weight phosphatase family; Region: LMWPc; cd00115
56110008355	active site
56110008356	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
56110008357	arsenical-resistance protein; Region: acr3; TIGR00832
56110008358	phosphate binding protein; Region: ptsS_2; TIGR02136
56110008359	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110008360	dimerization interface [polypeptide binding]; other site
56110008361	putative DNA binding site [nucleotide binding]; other site
56110008362	putative Zn2+ binding site [ion binding]; other site
56110008363	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
56110008364	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
56110008365	homodimer interface [polypeptide binding]; other site
56110008366	metal binding site [ion binding]; metal-binding site
56110008367	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
56110008368	homodimer interface [polypeptide binding]; other site
56110008369	active site
56110008370	putative chemical substrate binding site [chemical binding]; other site
56110008371	metal binding site [ion binding]; metal-binding site
56110008372	XisI protein; Region: XisI; pfam08869
56110008373	XisH protein; Region: XisH; pfam08814
56110008374	Uncharacterized metal-binding protein (DUF2227); Region: DUF2227; pfam09988
56110008375	hypothetical protein; Reviewed; Region: PRK00024
56110008376	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
56110008377	MPN+ (JAMM) motif; other site
56110008378	Zinc-binding site [ion binding]; other site
56110008379	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
56110008380	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
56110008381	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
56110008382	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110008383	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
56110008384	catalytic residues [active]
56110008385	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
56110008386	Peptidase S8 family domain in Protein convertases; Region: Peptidases_S8_Protein_convertases_Kexins_Furin-lik; cd04059
56110008387	active site
56110008388	catalytic triad [active]
56110008389	calcium binding site 2 [ion binding]; other site
56110008390	calcium binding site 3 [ion binding]; other site
56110008391	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
56110008392	Calx-beta domain; Region: Calx-beta; cl02522
56110008393	Calx-beta domain; Region: Calx-beta; cl02522
56110008394	Calx-beta domain; Region: Calx-beta; cl02522
56110008395	Calx-beta domain; Region: Calx-beta; cl02522
56110008396	Family description; Region: VCBS; pfam13517
56110008397	Family description; Region: VCBS; pfam13517
56110008398	Family description; Region: VCBS; pfam13517
56110008399	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
56110008400	Interdomain contacts; other site
56110008401	Cytokine receptor motif; other site
56110008402	Beta-propeller repeat; Region: SBBP; pfam06739
56110008403	FOG: WD40-like repeat [Function unknown]; Region: COG1520
56110008404	Beta-propeller repeat; Region: SBBP; pfam06739
56110008405	Beta-propeller repeat; Region: SBBP; pfam06739
56110008406	Beta-propeller repeat; Region: SBBP; pfam06739
56110008407	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110008408	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110008409	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
56110008410	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
56110008411	Surface antigen; Region: Bac_surface_Ag; pfam01103
56110008412	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008413	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110008414	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110008415	CHAT domain; Region: CHAT; cl17868
56110008416	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110008417	CHASE2 domain; Region: CHASE2; pfam05226
56110008418	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110008419	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
56110008420	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
56110008421	Transposase [DNA replication, recombination, and repair]; Region: COG5421
56110008422	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
56110008423	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
56110008424	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
56110008425	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
56110008426	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
56110008427	Transposase [DNA replication, recombination, and repair]; Region: COG5421
56110008428	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
56110008429	ligand binding site [chemical binding]; other site
56110008430	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110008431	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110008432	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
56110008433	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
56110008434	CHAT domain; Region: CHAT; cl17868
56110008435	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110008436	cyclase homology domain; Region: CHD; cd07302
56110008437	nucleotidyl binding site; other site
56110008438	metal binding site [ion binding]; metal-binding site
56110008439	dimer interface [polypeptide binding]; other site
56110008440	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
56110008441	photosystem I assembly protein Ycf3; Provisional; Region: PRK02603
56110008442	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008443	binding surface
56110008444	TPR motif; other site
56110008445	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
56110008446	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
56110008447	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
56110008448	cytochrome c-550; Provisional; Region: psbV; cl17239
56110008449	cytochrome c-550; Provisional; Region: psbV; cl17239
56110008450	cytochrome c-550; Provisional; Region: psbV; PRK13621
56110008451	FOG: CBS domain [General function prediction only]; Region: COG0517
56110008452	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110008453	FOG: CBS domain [General function prediction only]; Region: COG0517
56110008454	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110008455	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110008456	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110008457	metal binding site [ion binding]; metal-binding site
56110008458	active site
56110008459	I-site; other site
56110008460	Cytochrome c; Region: Cytochrom_C; cl11414
56110008461	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
56110008462	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
56110008463	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110008464	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110008465	S-adenosylmethionine binding site [chemical binding]; other site
56110008466	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110008467	S-adenosylmethionine binding site [chemical binding]; other site
56110008468	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110008469	S-adenosylmethionine binding site [chemical binding]; other site
56110008470	Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170
56110008471	rod shape-determining protein MreB; Provisional; Region: PRK13930
56110008472	nucleotide binding site [chemical binding]; other site
56110008473	putative NEF/HSP70 interaction site [polypeptide binding]; other site
56110008474	SBD interface [polypeptide binding]; other site
56110008475	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110008476	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110008477	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008478	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008479	binding surface
56110008480	TPR motif; other site
56110008481	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008482	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008483	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008484	binding surface
56110008485	TPR motif; other site
56110008486	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008487	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008488	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008489	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008490	binding surface
56110008491	TPR motif; other site
56110008492	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008493	CHAT domain; Region: CHAT; pfam12770
56110008494	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
56110008495	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008496	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008497	binding surface
56110008498	TPR motif; other site
56110008499	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008500	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008501	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008502	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008503	binding surface
56110008504	TPR motif; other site
56110008505	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008506	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008507	CHAT domain; Region: CHAT; pfam12770
56110008508	Caspase domain; Region: Peptidase_C14; pfam00656
56110008509	Domain of unknown function (DUF4384); Region: DUF4384; pfam14326
56110008510	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110008511	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110008512	Predicted membrane protein [Function unknown]; Region: COG3374
56110008513	Protein of unknown function (DUF981); Region: DUF981; pfam06168
56110008514	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
56110008515	Predicted membrane protein [Function unknown]; Region: COG1971
56110008516	Domain of unknown function DUF; Region: DUF204; pfam02659
56110008517	Domain of unknown function DUF; Region: DUF204; pfam02659
56110008518	aspartate aminotransferase; Provisional; Region: PRK05957
56110008519	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110008520	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110008521	homodimer interface [polypeptide binding]; other site
56110008522	catalytic residue [active]
56110008523	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
56110008524	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
56110008525	active site
56110008526	trimer interface [polypeptide binding]; other site
56110008527	allosteric site; other site
56110008528	active site lid [active]
56110008529	hexamer (dimer of trimers) interface [polypeptide binding]; other site
56110008530	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
56110008531	active site
56110008532	catalytic triad [active]
56110008533	oxyanion hole [active]
56110008534	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
56110008535	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110008536	catalytic triad [active]
56110008537	TPR repeat; Region: TPR_11; pfam13414
56110008538	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008539	binding surface
56110008540	TPR motif; other site
56110008541	TPR repeat; Region: TPR_11; pfam13414
56110008542	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110008543	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
56110008544	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
56110008545	ABC-ATPase subunit  interface; other site
56110008546	dimer interface [polypeptide binding]; other site
56110008547	putative PBP binding regions; other site
56110008548	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
56110008549	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
56110008550	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
56110008551	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
56110008552	metal binding site [ion binding]; metal-binding site
56110008553	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110008554	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
56110008555	ligand binding site [chemical binding]; other site
56110008556	flexible hinge region; other site
56110008557	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110008558	putative switch regulator; other site
56110008559	non-specific DNA interactions [nucleotide binding]; other site
56110008560	DNA binding site [nucleotide binding]
56110008561	sequence specific DNA binding site [nucleotide binding]; other site
56110008562	putative cAMP binding site [chemical binding]; other site
56110008563	HupE / UreJ protein; Region: HupE_UreJ; pfam04955
56110008564	cobalamin biosynthesis protein CobW; Region: CobW; TIGR02475
56110008565	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
56110008566	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
56110008567	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
56110008568	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110008569	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110008570	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110008571	active site
56110008572	phosphorylation site [posttranslational modification]
56110008573	intermolecular recognition site; other site
56110008574	dimerization interface [polypeptide binding]; other site
56110008575	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110008576	DNA binding site [nucleotide binding]
56110008577	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
56110008578	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110008579	dimerization interface [polypeptide binding]; other site
56110008580	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110008581	dimer interface [polypeptide binding]; other site
56110008582	phosphorylation site [posttranslational modification]
56110008583	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110008584	ATP binding site [chemical binding]; other site
56110008585	Mg2+ binding site [ion binding]; other site
56110008586	G-X-G motif; other site
56110008587	YcfA-like protein; Region: YcfA; pfam07927
56110008588	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
56110008589	Protein of unknown function (DUF2281); Region: DUF2281; pfam10047
56110008590	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
56110008591	oligomeric interface; other site
56110008592	putative active site [active]
56110008593	homodimer interface [polypeptide binding]; other site
56110008594	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110008595	putative active site [active]
56110008596	Predicted aspartyl protease [Posttranslational modification, protein turnover, chaperones]; Region: COG5550; cl17622
56110008597	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110008598	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
56110008599	Domain of unknown function (DUF3368); Region: DUF3368; pfam11848
56110008600	Domain of unknown function (DUF3825); Region: DUF3825; pfam12873
56110008601	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110008602	Walker A motif; other site
56110008603	ATP binding site [chemical binding]; other site
56110008604	Walker B motif; other site
56110008605	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
56110008606	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
56110008607	putative catalytic cysteine [active]
56110008608	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
56110008609	putative active site [active]
56110008610	metal binding site [ion binding]; metal-binding site
56110008611	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110008612	active site
56110008613	NTP binding site [chemical binding]; other site
56110008614	metal binding triad [ion binding]; metal-binding site
56110008615	Uncharacterized conserved protein [Function unknown]; Region: COG4938
56110008616	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110008617	Walker A/P-loop; other site
56110008618	ATP binding site [chemical binding]; other site
56110008619	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110008620	Walker B; other site
56110008621	D-loop; other site
56110008622	H-loop/switch region; other site
56110008623	Protein of unknown function (DUF3696); Region: DUF3696; pfam12476
56110008624	Protein of unknown function DUF262; Region: DUF262; pfam03235
56110008625	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
56110008626	Fasciclin domain; Region: Fasciclin; pfam02469
56110008627	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
56110008628	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
56110008629	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110008630	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
56110008631	putative metal binding site; other site
56110008632	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008633	binding surface
56110008634	TPR motif; other site
56110008635	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008636	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008637	binding surface
56110008638	TPR repeat; Region: TPR_11; pfam13414
56110008639	TPR motif; other site
56110008640	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110008641	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110008642	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
56110008643	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
56110008644	GTP/Mg2+ binding site [chemical binding]; other site
56110008645	G4 box; other site
56110008646	G5 box; other site
56110008647	G1 box; other site
56110008648	Switch I region; other site
56110008649	G2 box; other site
56110008650	G3 box; other site
56110008651	Switch II region; other site
56110008652	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110008653	Ligand Binding Site [chemical binding]; other site
56110008654	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
56110008655	Phosphoglycerate kinase; Region: PGK; pfam00162
56110008656	substrate binding site [chemical binding]; other site
56110008657	hinge regions; other site
56110008658	ADP binding site [chemical binding]; other site
56110008659	catalytic site [active]
56110008660	AAA domain; Region: AAA_21; pfam13304
56110008661	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110008662	Walker B; other site
56110008663	D-loop; other site
56110008664	H-loop/switch region; other site
56110008665	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
56110008666	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
56110008667	dimer interface [polypeptide binding]; other site
56110008668	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110008669	catalytic residue [active]
56110008670	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
56110008671	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
56110008672	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
56110008673	Walker A/P-loop; other site
56110008674	ATP binding site [chemical binding]; other site
56110008675	Q-loop/lid; other site
56110008676	ABC transporter signature motif; other site
56110008677	Walker B; other site
56110008678	D-loop; other site
56110008679	H-loop/switch region; other site
56110008680	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
56110008681	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
56110008682	Walker A/P-loop; other site
56110008683	ATP binding site [chemical binding]; other site
56110008684	Q-loop/lid; other site
56110008685	ABC transporter signature motif; other site
56110008686	Walker B; other site
56110008687	D-loop; other site
56110008688	H-loop/switch region; other site
56110008689	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
56110008690	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
56110008691	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
56110008692	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
56110008693	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
56110008694	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110008695	putative active site [active]
56110008696	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110008697	TPR repeat; Region: TPR_11; pfam13414
56110008698	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008699	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008700	binding surface
56110008701	TPR motif; other site
56110008702	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008703	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008704	binding surface
56110008705	TPR motif; other site
56110008706	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008707	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008708	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008709	binding surface
56110008710	TPR motif; other site
56110008711	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008712	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008713	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008714	binding surface
56110008715	TPR motif; other site
56110008716	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110008717	CHAT domain; Region: CHAT; pfam12770
56110008718	Domain of unknown function (DUF1795); Region: DUF1795; cl02256
56110008719	Transposase IS200 like; Region: Y1_Tnp; pfam01797
56110008720	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110008721	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110008722	active site
56110008723	ATP binding site [chemical binding]; other site
56110008724	substrate binding site [chemical binding]; other site
56110008725	activation loop (A-loop); other site
56110008726	Domain of unknown function (DUF1795); Region: DUF1795; cl02256
56110008727	DNA photolyase; Region: DNA_photolyase; pfam00875
56110008728	cryptochrome, DASH family; Region: crypto_DASH; TIGR02765
56110008729	NAD(P)H-quinone oxidoreductase subunit 4; Provisional; Region: PRK02546
56110008730	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110008731	NAD(P)H-quinone oxidoreductase subunit F; Validated; Region: PRK07376
56110008732	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
56110008733	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110008734	NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus; Region: Oxidored_q1_C; pfam01010
56110008735	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
56110008736	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110008737	catalytic residues [active]
56110008738	AbrB-like transcriptional regulator; Region: AbrB-like; pfam14250
56110008739	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
56110008740	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
56110008741	active site
56110008742	metal binding site [ion binding]; metal-binding site
56110008743	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110008744	putative active site [active]
56110008745	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
56110008746	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
56110008747	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; cl15441
56110008748	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110008749	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110008750	active site
56110008751	ATP binding site [chemical binding]; other site
56110008752	substrate binding site [chemical binding]; other site
56110008753	activation loop (A-loop); other site
56110008754	Protein kinase domain; Region: Pkinase; pfam00069
56110008755	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110008756	active site
56110008757	ATP binding site [chemical binding]; other site
56110008758	substrate binding site [chemical binding]; other site
56110008759	activation loop (A-loop); other site
56110008760	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110008761	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008762	binding surface
56110008763	TPR motif; other site
56110008764	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008765	binding surface
56110008766	TPR motif; other site
56110008767	TPR repeat; Region: TPR_11; pfam13414
56110008768	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008769	binding surface
56110008770	TPR motif; other site
56110008771	TPR repeat; Region: TPR_11; pfam13414
56110008772	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
56110008773	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
56110008774	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
56110008775	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
56110008776	C-terminal peptidase (prc); Region: prc; TIGR00225
56110008777	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
56110008778	protein binding site [polypeptide binding]; other site
56110008779	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
56110008780	Catalytic dyad [active]
56110008781	AAA domain; Region: AAA_33; pfam13671
56110008782	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110008783	G1 box; other site
56110008784	GTP/Mg2+ binding site [chemical binding]; other site
56110008785	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110008786	dimer interface [polypeptide binding]; other site
56110008787	phosphorylation site [posttranslational modification]
56110008788	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110008789	ATP binding site [chemical binding]; other site
56110008790	Mg2+ binding site [ion binding]; other site
56110008791	G-X-G motif; other site
56110008792	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008793	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008794	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110008795	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008796	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008797	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008798	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008799	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
56110008800	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
56110008801	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110008802	Walker A motif; other site
56110008803	ATP binding site [chemical binding]; other site
56110008804	Walker B motif; other site
56110008805	arginine finger; other site
56110008806	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
56110008807	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
56110008808	ThiF family; Region: ThiF; pfam00899
56110008809	ATP binding site [chemical binding]; other site
56110008810	substrate interface [chemical binding]; other site
56110008811	Cache domain; Region: Cache_1; pfam02743
56110008812	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
56110008813	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110008814	dimerization interface [polypeptide binding]; other site
56110008815	PAS domain S-box; Region: sensory_box; TIGR00229
56110008816	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008817	putative active site [active]
56110008818	heme pocket [chemical binding]; other site
56110008819	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008820	PAS fold; Region: PAS_3; pfam08447
56110008821	putative active site [active]
56110008822	heme pocket [chemical binding]; other site
56110008823	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008824	PAS fold; Region: PAS_3; pfam08447
56110008825	putative active site [active]
56110008826	heme pocket [chemical binding]; other site
56110008827	PAS domain S-box; Region: sensory_box; TIGR00229
56110008828	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008829	putative active site [active]
56110008830	heme pocket [chemical binding]; other site
56110008831	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110008832	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110008833	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008834	putative active site [active]
56110008835	heme pocket [chemical binding]; other site
56110008836	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110008837	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008838	putative active site [active]
56110008839	heme pocket [chemical binding]; other site
56110008840	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008841	putative active site [active]
56110008842	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110008843	heme pocket [chemical binding]; other site
56110008844	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110008845	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110008846	putative active site [active]
56110008847	heme pocket [chemical binding]; other site
56110008848	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110008849	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110008850	dimer interface [polypeptide binding]; other site
56110008851	phosphorylation site [posttranslational modification]
56110008852	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110008853	ATP binding site [chemical binding]; other site
56110008854	Mg2+ binding site [ion binding]; other site
56110008855	G-X-G motif; other site
56110008856	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110008857	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110008858	active site
56110008859	phosphorylation site [posttranslational modification]
56110008860	intermolecular recognition site; other site
56110008861	dimerization interface [polypeptide binding]; other site
56110008862	Response regulator receiver domain; Region: Response_reg; pfam00072
56110008863	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110008864	active site
56110008865	phosphorylation site [posttranslational modification]
56110008866	intermolecular recognition site; other site
56110008867	dimerization interface [polypeptide binding]; other site
56110008868	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110008869	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110008870	dimer interface [polypeptide binding]; other site
56110008871	phosphorylation site [posttranslational modification]
56110008872	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110008873	ATP binding site [chemical binding]; other site
56110008874	Mg2+ binding site [ion binding]; other site
56110008875	G-X-G motif; other site
56110008876	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110008877	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110008878	active site
56110008879	phosphorylation site [posttranslational modification]
56110008880	intermolecular recognition site; other site
56110008881	dimerization interface [polypeptide binding]; other site
56110008882	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
56110008883	cytosine deaminase; Provisional; Region: PRK09230
56110008884	active site
56110008885	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110008886	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008887	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110008888	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008889	binding surface
56110008890	TPR repeat; Region: TPR_11; pfam13414
56110008891	TPR motif; other site
56110008892	TPR repeat; Region: TPR_11; pfam13414
56110008893	TPR repeat; Region: TPR_11; pfam13414
56110008894	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008895	binding surface
56110008896	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110008897	TPR motif; other site
56110008898	TPR repeat; Region: TPR_11; pfam13414
56110008899	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008900	binding surface
56110008901	TPR motif; other site
56110008902	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110008903	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008904	binding surface
56110008905	TPR motif; other site
56110008906	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008907	binding surface
56110008908	TPR motif; other site
56110008909	TPR repeat; Region: TPR_11; pfam13414
56110008910	Domain of unknown function (DUF4278); Region: DUF4278; pfam14105
56110008911	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
56110008912	SmpB-tmRNA interface; other site
56110008913	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
56110008914	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110008915	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110008916	Phytochrome region; Region: PHY; pfam00360
56110008917	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110008918	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110008919	metal binding site [ion binding]; metal-binding site
56110008920	active site
56110008921	I-site; other site
56110008922	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110008923	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
56110008924	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
56110008925	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
56110008926	D-inositol-3-phosphate glycosyltransferase; Region: mycothiol_MshA; TIGR03449
56110008927	putative ADP-binding pocket [chemical binding]; other site
56110008928	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
56110008929	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110008930	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110008931	Probable transposase; Region: OrfB_IS605; pfam01385
56110008932	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110008933	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
56110008934	NlpC/P60 family; Region: NLPC_P60; pfam00877
56110008935	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110008936	Major Facilitator Superfamily; Region: MFS_1; pfam07690
56110008937	putative substrate translocation pore; other site
56110008938	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
56110008939	trimer interface [polypeptide binding]; other site
56110008940	dimer interface [polypeptide binding]; other site
56110008941	putative active site [active]
56110008942	2TM domain; Region: 2TM; pfam13239
56110008943	Protein of unknown function (DUF3181); Region: DUF3181; pfam11378
56110008944	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
56110008945	catalytic core [active]
56110008946	citrate synthase; Provisional; Region: PRK14036
56110008947	Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_1_1; cd06112
56110008948	dimer interface [polypeptide binding]; other site
56110008949	active site
56110008950	citrylCoA binding site [chemical binding]; other site
56110008951	oxalacetate/citrate binding site [chemical binding]; other site
56110008952	coenzyme A binding site [chemical binding]; other site
56110008953	catalytic triad [active]
56110008954	NADH dehydrogenase; Region: NADHdh; cl00469
56110008955	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
56110008956	NADH-plastoquinone oxidoreductase subunit I protein; Region: ndhI; TIGR00403
56110008957	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
56110008958	NADH dehydrogenase subunit 6; Region: ndhG; CHL00016
56110008959	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
56110008960	NADH dehydrogenase subunit 4L; Region: ndhE; CHL00015
56110008961	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02645
56110008962	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
56110008963	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5381
56110008964	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
56110008965	photosystem II protein Psb27; Region: PS_II_psb27; TIGR03044
56110008966	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
56110008967	phosphoglyceromutase; Provisional; Region: PRK05434
56110008968	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
56110008969	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
56110008970	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
56110008971	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110008972	binding surface
56110008973	TPR repeat; Region: TPR_11; pfam13414
56110008974	TPR motif; other site
56110008975	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
56110008976	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110008977	putative active site [active]
56110008978	Protein of unknown function (DUF3370); Region: DUF3370; pfam11850
56110008979	NlpC/P60 family; Region: NLPC_P60; cl17555
56110008980	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
56110008981	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110008982	motif II; other site
56110008983	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110008984	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110008985	ligand binding site [chemical binding]; other site
56110008986	flexible hinge region; other site
56110008987	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
56110008988	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110008989	Walker A motif; other site
56110008990	ATP binding site [chemical binding]; other site
56110008991	Walker B motif; other site
56110008992	Polyferredoxin [Energy production and conversion]; Region: NapH; COG0348
56110008993	4Fe-4S binding domain; Region: Fer4_5; pfam12801
56110008994	4Fe-4S binding domain; Region: Fer4_5; pfam12801
56110008995	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
56110008996	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
56110008997	nucleotide binding site [chemical binding]; other site
56110008998	SulA interaction site; other site
56110008999	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110009000	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
56110009001	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110009002	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
56110009003	Pirin-related protein [General function prediction only]; Region: COG1741
56110009004	Pirin; Region: Pirin; pfam02678
56110009005	Predicted transcriptional regulators [Transcription]; Region: COG1733
56110009006	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110009007	dimerization interface [polypeptide binding]; other site
56110009008	putative DNA binding site [nucleotide binding]; other site
56110009009	putative Zn2+ binding site [ion binding]; other site
56110009010	FOG: CBS domain [General function prediction only]; Region: COG0517
56110009011	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110009012	FOG: CBS domain [General function prediction only]; Region: COG0517
56110009013	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with a PAS domain, a GGDEF (DiGuanylate-Cyclase (DGC) domain, and a DUF1 domain downstream. PAS domains have been found to bind ligands, and to act...; Region: CBS_pair_PAS_GGDEF_DUF1_assoc; cd04611
56110009014	PAS domain; Region: PAS_9; pfam13426
56110009015	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009016	putative active site [active]
56110009017	heme pocket [chemical binding]; other site
56110009018	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110009019	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110009020	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110009021	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110009022	metal binding site [ion binding]; metal-binding site
56110009023	active site
56110009024	I-site; other site
56110009025	recombination factor protein RarA/unknown domain fusion protein; Reviewed; Region: PRK13341
56110009026	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110009027	Walker A motif; other site
56110009028	ATP binding site [chemical binding]; other site
56110009029	Walker B motif; other site
56110009030	arginine finger; other site
56110009031	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
56110009032	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
56110009033	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
56110009034	active site
56110009035	metal binding site [ion binding]; metal-binding site
56110009036	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
56110009037	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
56110009038	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
56110009039	catalytic residues [active]
56110009040	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
56110009041	dimanganese center [ion binding]; other site
56110009042	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110009043	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110009044	ligand binding site [chemical binding]; other site
56110009045	flexible hinge region; other site
56110009046	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
56110009047	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
56110009048	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
56110009049	protein binding site [polypeptide binding]; other site
56110009050	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009051	putative active site [active]
56110009052	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009053	putative active site [active]
56110009054	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14457
56110009055	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110009056	FeS/SAM binding site; other site
56110009057	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110009058	cyclase homology domain; Region: CHD; cd07302
56110009059	nucleotidyl binding site; other site
56110009060	metal binding site [ion binding]; metal-binding site
56110009061	dimer interface [polypeptide binding]; other site
56110009062	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
56110009063	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110009064	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110009065	ligand binding site [chemical binding]; other site
56110009066	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110009067	flexible hinge region; other site
56110009068	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009069	dimer interface [polypeptide binding]; other site
56110009070	phosphorylation site [posttranslational modification]
56110009071	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009072	ATP binding site [chemical binding]; other site
56110009073	Mg2+ binding site [ion binding]; other site
56110009074	G-X-G motif; other site
56110009075	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK05952
56110009076	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
56110009077	dimer interface [polypeptide binding]; other site
56110009078	active site
56110009079	cyclophilin_TLP40_like: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) similar ot the Spinach thylakoid lumen protein TLP40. Compared to the archetypal cyclophilin Human cyclophilin A, these proteins have similar peptidylprolyl...; Region: cyclophilin_TLP40_like; cd01924
56110009080	active site
56110009081	photosystem I assembly protein Ycf4; Provisional; Region: PRK02542
56110009082	D2 subunit  of photosystem II (PS II); Region: Photosystem-II_D2; cd09288
56110009083	D1 interface; other site
56110009084	chlorophyll binding site; other site
56110009085	pheophytin binding site; other site
56110009086	beta carotene binding site; other site
56110009087	cytochrome b559 beta interface; other site
56110009088	quinone binding site; other site
56110009089	cytochrome b559 alpha interface; other site
56110009090	protein J interface; other site
56110009091	protein H interface; other site
56110009092	protein X interface; other site
56110009093	core light harvesting protein interface; other site
56110009094	protein L interface; other site
56110009095	CP43 interface; other site
56110009096	protein T interface; other site
56110009097	Fe binding site [ion binding]; other site
56110009098	protein M interface; other site
56110009099	Mn-stabilizing polypeptide interface; other site
56110009100	bromide binding site; other site
56110009101	cytochrome c-550 interface; other site
56110009102	photosystem II 44 kDa protein; Region: psbC; CHL00035
56110009103	photosystem II 44 kDa subunit reaction center protein (also called P6 protein, CP43), bacterial and chloroplast; Region: psbC; TIGR01153
56110009104	Proto-chlorophyllide reductase 57 kD subunit; Region: PCP_red; pfam08369
56110009105	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
56110009106	Protein of unknown function (DUF1385); Region: DUF1385; cl01595
56110009107	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
56110009108	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110009109	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009110	active site
56110009111	phosphorylation site [posttranslational modification]
56110009112	intermolecular recognition site; other site
56110009113	dimerization interface [polypeptide binding]; other site
56110009114	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110009115	DNA binding site [nucleotide binding]
56110009116	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009117	dimer interface [polypeptide binding]; other site
56110009118	phosphorylation site [posttranslational modification]
56110009119	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009120	ATP binding site [chemical binding]; other site
56110009121	Mg2+ binding site [ion binding]; other site
56110009122	G-X-G motif; other site
56110009123	Uncharacterized conserved protein [Function unknown]; Region: COG4279
56110009124	SWIM zinc finger; Region: SWIM; pfam04434
56110009125	SNF2 Helicase protein; Region: DUF3670; pfam12419
56110009126	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
56110009127	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110009128	ATP binding site [chemical binding]; other site
56110009129	putative Mg++ binding site [ion binding]; other site
56110009130	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110009131	nucleotide binding region [chemical binding]; other site
56110009132	ATP-binding site [chemical binding]; other site
56110009133	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110009134	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110009135	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110009136	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
56110009137	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
56110009138	RNase E interface [polypeptide binding]; other site
56110009139	trimer interface [polypeptide binding]; other site
56110009140	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
56110009141	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
56110009142	RNase E interface [polypeptide binding]; other site
56110009143	trimer interface [polypeptide binding]; other site
56110009144	active site
56110009145	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
56110009146	putative nucleic acid binding region [nucleotide binding]; other site
56110009147	G-X-X-G motif; other site
56110009148	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
56110009149	RNA binding site [nucleotide binding]; other site
56110009150	domain interface; other site
56110009151	Domain of unknown function (DUF4327); Region: DUF4327; pfam14217
56110009152	triosephosphate isomerase; Provisional; Region: PRK14565
56110009153	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
56110009154	substrate binding site [chemical binding]; other site
56110009155	dimer interface [polypeptide binding]; other site
56110009156	catalytic triad [active]
56110009157	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110009158	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110009159	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110009160	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
56110009161	dihydropteroate synthase; Region: DHPS; TIGR01496
56110009162	substrate binding pocket [chemical binding]; other site
56110009163	dimer interface [polypeptide binding]; other site
56110009164	inhibitor binding site; inhibition site
56110009165	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
56110009166	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
56110009167	Alpha/beta hydrolase of unknown function (DUF1400); Region: DUF1400; pfam07176
56110009168	Predicted dienelactone hydrolase [General function prediction only]; Region: COG4188
56110009169	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110009170	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110009171	DDE_Tnp_1-like zinc-ribbon; Region: Tnp_zf-ribbon_2; pfam13842
56110009172	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110009173	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110009174	active site
56110009175	ATP binding site [chemical binding]; other site
56110009176	substrate binding site [chemical binding]; other site
56110009177	activation loop (A-loop); other site
56110009178	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110009179	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110009180	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110009181	structural tetrad; other site
56110009182	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110009183	structural tetrad; other site
56110009184	Myxococcus xanthus DevT and related proteins, metallophosphatase domain; Region: MPP_DevT; cd07397
56110009185	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110009186	putative active site [active]
56110009187	putative metal binding site [ion binding]; other site
56110009188	quinolinate synthetase; Provisional; Region: PRK09375
56110009189	tellurium resistance terB-like protein; Region: terB_like; cd07177
56110009190	metal binding site [ion binding]; metal-binding site
56110009191	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110009192	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110009193	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110009194	putative active site [active]
56110009195	putative NTP binding site [chemical binding]; other site
56110009196	putative nucleic acid binding site [nucleotide binding]; other site
56110009197	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110009198	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110009199	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110009200	active site
56110009201	Homeodomain-like domain; Region: HTH_23; pfam13384
56110009202	Winged helix-turn helix; Region: HTH_29; pfam13551
56110009203	Winged helix-turn helix; Region: HTH_33; pfam13592
56110009204	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110009205	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110009206	Protein of unknown function (DUF4079); Region: DUF4079; pfam13301
56110009207	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
56110009208	dimer interface [polypeptide binding]; other site
56110009209	motif 1; other site
56110009210	active site
56110009211	motif 2; other site
56110009212	motif 3; other site
56110009213	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110009214	HNH endonuclease; Region: HNH; pfam01844
56110009215	active site
56110009216	Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain [DNA replication, recombination, and repair]; Region: COG1107
56110009217	Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612
56110009218	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
56110009219	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110009220	Walker A/P-loop; other site
56110009221	ATP binding site [chemical binding]; other site
56110009222	Q-loop/lid; other site
56110009223	ABC transporter signature motif; other site
56110009224	Walker B; other site
56110009225	D-loop; other site
56110009226	H-loop/switch region; other site
56110009227	Tryptophan-rich protein (DUF2389); Region: DUF2389; pfam09493
56110009228	Rhomboid family; Region: Rhomboid; pfam01694
56110009229	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
56110009230	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
56110009231	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
56110009232	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
56110009233	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
56110009234	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110009235	Predicted transcriptional regulators [Transcription]; Region: COG1695
56110009236	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
56110009237	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
56110009238	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110009239	putative active site [active]
56110009240	putative metal binding site [ion binding]; other site
56110009241	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
56110009242	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110009243	P-loop; other site
56110009244	Magnesium ion binding site [ion binding]; other site
56110009245	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
56110009246	putative FeS-containing Cyanobacterial-specific oxidoreductase; Region: cyano_FeS_chp; TIGR03279
56110009247	Protein of unknown function (DUF512); Region: DUF512; pfam04459
56110009248	Protein kinase domain; Region: Pkinase; pfam00069
56110009249	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110009250	active site
56110009251	ATP binding site [chemical binding]; other site
56110009252	substrate binding site [chemical binding]; other site
56110009253	activation loop (A-loop); other site
56110009254	AAA ATPase domain; Region: AAA_16; pfam13191
56110009255	Predicted ATPase [General function prediction only]; Region: COG3899
56110009256	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110009257	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110009258	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110009259	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009260	ATP binding site [chemical binding]; other site
56110009261	Mg2+ binding site [ion binding]; other site
56110009262	G-X-G motif; other site
56110009263	Bacitracin resistance protein BacA; Region: BacA; pfam02673
56110009264	Protein of unknown function (DUF3120); Region: DUF3120; pfam11318
56110009265	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110009266	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110009267	phosphopeptide binding site; other site
56110009268	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110009269	cyclase homology domain; Region: CHD; cd07302
56110009270	nucleotidyl binding site; other site
56110009271	metal binding site [ion binding]; metal-binding site
56110009272	dimer interface [polypeptide binding]; other site
56110009273	Photosystem II 12 kDa extrinsic protein (PsbU); Region: PsbU; pfam06514
56110009274	L-aspartate oxidase; Provisional; Region: PRK07395
56110009275	L-aspartate oxidase; Provisional; Region: PRK06175
56110009276	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
56110009277	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110009278	CHASE2 domain; Region: CHASE2; pfam05226
56110009279	PAS domain S-box; Region: sensory_box; TIGR00229
56110009280	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009281	putative active site [active]
56110009282	heme pocket [chemical binding]; other site
56110009283	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110009284	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110009285	metal binding site [ion binding]; metal-binding site
56110009286	active site
56110009287	I-site; other site
56110009288	Vitamin K epoxide reductase family in bacteria and plants; Region: VKOR_1; cd12916
56110009289	substrate binding site [chemical binding]; other site
56110009290	putative active site [active]
56110009291	redox center [active]
56110009292	Protein Disulfide Isomerase (PDIa) family, redox active TRX domains; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family include PDI...; Region: PDI_a_family; cd02961
56110009293	catalytic residues [active]
56110009294	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cd04722
56110009295	phosphate binding site [ion binding]; other site
56110009296	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
56110009297	Protein of unknown function DUF58; Region: DUF58; pfam01882
56110009298	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
56110009299	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
56110009300	active site
56110009301	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110009302	TPR motif; other site
56110009303	Protein of unknown function (DUF1257); Region: DUF1257; pfam06868
56110009304	Ycf46; Provisional; Region: ycf46; CHL00195
56110009305	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110009306	Walker A motif; other site
56110009307	ATP binding site [chemical binding]; other site
56110009308	Walker B motif; other site
56110009309	arginine finger; other site
56110009310	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110009311	AAA domain; Region: AAA_22; pfam13401
56110009312	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
56110009313	metal ion-dependent adhesion site (MIDAS); other site
56110009314	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
56110009315	Domain of unknown function (DUF3368); Region: DUF3368; pfam11848
56110009316	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110009317	Protein of unknown function (DUF4058); Region: DUF4058; pfam13267
56110009318	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
56110009319	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
56110009320	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
56110009321	active site
56110009322	dimer interface [polypeptide binding]; other site
56110009323	motif 1; other site
56110009324	motif 2; other site
56110009325	motif 3; other site
56110009326	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
56110009327	anticodon binding site; other site
56110009328	Protein of unknown function (DUF2605); Region: DUF2605; pfam10792
56110009329	Protein of unknown function (DUF2973); Region: DUF2973; pfam11189
56110009330	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009331	putative active site [active]
56110009332	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_29; cd04688
56110009333	nudix motif; other site
56110009334	Protein of unknown function (DUF3531); Region: DUF3531; pfam12049
56110009335	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110009336	TPR motif; other site
56110009337	TPR repeat; Region: TPR_11; pfam13414
56110009338	binding surface
56110009339	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
56110009340	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
56110009341	Walker A/P-loop; other site
56110009342	ATP binding site [chemical binding]; other site
56110009343	Q-loop/lid; other site
56110009344	ABC transporter signature motif; other site
56110009345	Walker B; other site
56110009346	D-loop; other site
56110009347	H-loop/switch region; other site
56110009348	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
56110009349	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110009350	S-adenosylmethionine binding site [chemical binding]; other site
56110009351	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009352	PAS domain; Region: PAS_9; pfam13426
56110009353	putative active site [active]
56110009354	heme pocket [chemical binding]; other site
56110009355	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110009356	GAF domain; Region: GAF_3; pfam13492
56110009357	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110009358	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110009359	metal binding site [ion binding]; metal-binding site
56110009360	active site
56110009361	I-site; other site
56110009362	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
56110009363	Chemotaxis phosphatase CheX; Region: CheX; cl15816
56110009364	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
56110009365	Response regulator receiver domain; Region: Response_reg; pfam00072
56110009366	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009367	active site
56110009368	phosphorylation site [posttranslational modification]
56110009369	intermolecular recognition site; other site
56110009370	dimerization interface [polypeptide binding]; other site
56110009371	Transcriptional regulator [Transcription]; Region: LysR; COG0583
56110009372	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
56110009373	The C-terminal substrate binding of LysR-type transcriptional regulator (CbbR) of RubisCO operon, which is involved in the carbon dioxide fixation, contains the type 2 periplasmic binding fold; Region: PBP2_CbbR_RubisCO_like; cd08419
56110009374	putative dimerization interface [polypeptide binding]; other site
56110009375	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
56110009376	active site
56110009377	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110009378	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110009379	Probable transposase; Region: OrfB_IS605; pfam01385
56110009380	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009381	putative active site [active]
56110009382	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009383	putative active site [active]
56110009384	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009385	putative active site [active]
56110009386	putative high light inducible protein; Region: PHA02337
56110009387	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110009388	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110009389	binding surface
56110009390	TPR motif; other site
56110009391	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110009392	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110009393	binding surface
56110009394	TPR motif; other site
56110009395	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110009396	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110009397	binding surface
56110009398	TPR motif; other site
56110009399	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110009400	CHAT domain; Region: CHAT; pfam12770
56110009401	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
56110009402	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4719
56110009403	conserved repeat domain; Region: B_ant_repeat; TIGR01451
56110009404	cell surface protein SprA; Region: surface_SprA; TIGR04189
56110009405	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
56110009406	FlgD Ig-like domain; Region: FlgD_ig; pfam13860
56110009407	Domain of unknown function DUF11; Region: DUF11; pfam01345
56110009408	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110009409	S-adenosylmethionine binding site [chemical binding]; other site
56110009410	MORN repeat; Region: MORN; cl14787
56110009411	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
56110009412	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
56110009413	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
56110009414	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
56110009415	glutathione synthetase; Provisional; Region: PRK05246
56110009416	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
56110009417	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
56110009418	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
56110009419	GSH binding site [chemical binding]; other site
56110009420	catalytic residues [active]
56110009421	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110009422	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110009423	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110009424	putative active site [active]
56110009425	putative NTP binding site [chemical binding]; other site
56110009426	putative nucleic acid binding site [nucleotide binding]; other site
56110009427	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110009428	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110009429	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110009430	active site
56110009431	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
56110009432	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
56110009433	HflX GTPase family; Region: HflX; cd01878
56110009434	G1 box; other site
56110009435	GTP/Mg2+ binding site [chemical binding]; other site
56110009436	Switch I region; other site
56110009437	G2 box; other site
56110009438	G3 box; other site
56110009439	Switch II region; other site
56110009440	G4 box; other site
56110009441	G5 box; other site
56110009442	Protein of unknown function (DUF433); Region: DUF433; cl01030
56110009443	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009444	putative active site [active]
56110009445	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110009446	putative active site [active]
56110009447	L,L-diaminopimelate aminotransferase; Validated; Region: PRK07590
56110009448	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110009449	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110009450	homodimer interface [polypeptide binding]; other site
56110009451	catalytic residue [active]
56110009452	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110009453	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110009454	S-adenosylmethionine binding site [chemical binding]; other site
56110009455	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
56110009456	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
56110009457	superoxide dismutase; Provisional; Region: PRK10925
56110009458	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
56110009459	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
56110009460	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
56110009461	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
56110009462	Uncharacterized conserved protein [Function unknown]; Region: COG4715
56110009463	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
56110009464	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
56110009465	substrate binding site [chemical binding]; other site
56110009466	dimer interface [polypeptide binding]; other site
56110009467	ATP binding site [chemical binding]; other site
56110009468	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
56110009469	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110009470	active site
56110009471	phosphoenolpyruvate synthase; Region: PEP_synth; TIGR01418
56110009472	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
56110009473	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
56110009474	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
56110009475	Protein of unknown function (DUF1361); Region: DUF1361; cl01784
56110009476	Protein of unknown function (DUF1361); Region: DUF1361; pfam07099
56110009477	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2402
56110009478	major vault protein; Provisional; Region: PTZ00491
56110009479	Major Vault Protein repeat; Region: Vault; pfam01505
56110009480	Major Vault Protein repeat; Region: Vault; pfam01505
56110009481	Major Vault Protein repeat; Region: Vault; pfam01505
56110009482	Major Vault Protein repeat; Region: Vault; pfam01505
56110009483	Shoulder domain; Region: MVP_shoulder; pfam11978
56110009484	CHAT domain; Region: CHAT; pfam12770
56110009485	urease subunit alpha; Reviewed; Region: ureC; PRK13207
56110009486	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
56110009487	subunit interactions [polypeptide binding]; other site
56110009488	active site
56110009489	flap region; other site
56110009490	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
56110009491	4-aminobutyrate aminotransferase; Provisional; Region: PRK05769
56110009492	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
56110009493	inhibitor-cofactor binding pocket; inhibition site
56110009494	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110009495	catalytic residue [active]
56110009496	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
56110009497	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009498	PAS domain; Region: PAS_9; pfam13426
56110009499	putative active site [active]
56110009500	heme pocket [chemical binding]; other site
56110009501	PAS domain S-box; Region: sensory_box; TIGR00229
56110009502	PAS domain; Region: PAS_8; pfam13188
56110009503	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009504	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110009505	putative active site [active]
56110009506	heme pocket [chemical binding]; other site
56110009507	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009508	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110009509	putative active site [active]
56110009510	heme pocket [chemical binding]; other site
56110009511	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009512	putative active site [active]
56110009513	heme pocket [chemical binding]; other site
56110009514	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110009515	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110009516	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009517	dimer interface [polypeptide binding]; other site
56110009518	phosphorylation site [posttranslational modification]
56110009519	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009520	ATP binding site [chemical binding]; other site
56110009521	Mg2+ binding site [ion binding]; other site
56110009522	G-X-G motif; other site
56110009523	Response regulator receiver domain; Region: Response_reg; pfam00072
56110009524	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009525	active site
56110009526	phosphorylation site [posttranslational modification]
56110009527	intermolecular recognition site; other site
56110009528	dimerization interface [polypeptide binding]; other site
56110009529	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110009530	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009531	dimer interface [polypeptide binding]; other site
56110009532	phosphorylation site [posttranslational modification]
56110009533	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009534	ATP binding site [chemical binding]; other site
56110009535	Mg2+ binding site [ion binding]; other site
56110009536	G-X-G motif; other site
56110009537	Response regulator receiver domain; Region: Response_reg; pfam00072
56110009538	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009539	active site
56110009540	phosphorylation site [posttranslational modification]
56110009541	intermolecular recognition site; other site
56110009542	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110009543	dimerization interface [polypeptide binding]; other site
56110009544	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009545	dimer interface [polypeptide binding]; other site
56110009546	phosphorylation site [posttranslational modification]
56110009547	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009548	ATP binding site [chemical binding]; other site
56110009549	Mg2+ binding site [ion binding]; other site
56110009550	G-X-G motif; other site
56110009551	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009552	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110009553	active site
56110009554	phosphorylation site [posttranslational modification]
56110009555	intermolecular recognition site; other site
56110009556	dimerization interface [polypeptide binding]; other site
56110009557	Response regulator receiver domain; Region: Response_reg; pfam00072
56110009558	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009559	active site
56110009560	phosphorylation site [posttranslational modification]
56110009561	intermolecular recognition site; other site
56110009562	dimerization interface [polypeptide binding]; other site
56110009563	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
56110009564	CheC-like family; Region: CheC; pfam04509
56110009565	PAS fold; Region: PAS_4; pfam08448
56110009566	PAS fold; Region: PAS_3; pfam08447
56110009567	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009568	putative active site [active]
56110009569	heme pocket [chemical binding]; other site
56110009570	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110009571	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009572	putative active site [active]
56110009573	heme pocket [chemical binding]; other site
56110009574	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009575	dimer interface [polypeptide binding]; other site
56110009576	phosphorylation site [posttranslational modification]
56110009577	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009578	ATP binding site [chemical binding]; other site
56110009579	Mg2+ binding site [ion binding]; other site
56110009580	G-X-G motif; other site
56110009581	Response regulator receiver domain; Region: Response_reg; pfam00072
56110009582	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009583	active site
56110009584	phosphorylation site [posttranslational modification]
56110009585	intermolecular recognition site; other site
56110009586	dimerization interface [polypeptide binding]; other site
56110009587	Predicted flavoprotein [General function prediction only]; Region: COG0431
56110009588	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
56110009589	putative alpha-glucosidase; Provisional; Region: PRK10658
56110009590	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
56110009591	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
56110009592	trimer interface [polypeptide binding]; other site
56110009593	active site
56110009594	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
56110009595	catalytic site [active]
56110009596	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
56110009597	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
56110009598	NAD(P) binding site [chemical binding]; other site
56110009599	catalytic residues [active]
56110009600	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
56110009601	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110009602	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
56110009603	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
56110009604	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110009605	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
56110009606	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
56110009607	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110009608	Ligand Binding Site [chemical binding]; other site
56110009609	Mg2+ transporter (mgtE); Region: mgtE; TIGR00400
56110009610	MgtE intracellular N domain; Region: MgtE_N; smart00924
56110009611	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
56110009612	Divalent cation transporter; Region: MgtE; pfam01769
56110009613	Mg2+ transporter (mgtE); Region: mgtE; TIGR00400
56110009614	MgtE intracellular N domain; Region: MgtE_N; smart00924
56110009615	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
56110009616	Divalent cation transporter; Region: MgtE; pfam01769
56110009617	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110009618	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110009619	structural tetrad; other site
56110009620	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
56110009621	Histone deacetylase class IV also known as histone deacetylase 11; Region: HDAC_classIV; cd09993
56110009622	putative active site [active]
56110009623	Zn binding site [ion binding]; other site
56110009624	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
56110009625	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
56110009626	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
56110009627	putative dimer interface [polypeptide binding]; other site
56110009628	N-terminal domain interface [polypeptide binding]; other site
56110009629	putative substrate binding pocket (H-site) [chemical binding]; other site
56110009630	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
56110009631	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
56110009632	Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001
56110009633	inhibitor-cofactor binding pocket; inhibition site
56110009634	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110009635	catalytic residue [active]
56110009636	Condensation domain; Region: Condensation; pfam00668
56110009637	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110009638	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110009639	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110009640	acyl-activating enzyme (AAE) consensus motif; other site
56110009641	AMP binding site [chemical binding]; other site
56110009642	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110009643	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110009644	S-adenosylmethionine binding site [chemical binding]; other site
56110009645	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
56110009646	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009647	thioester reductase domain; Region: Thioester-redct; TIGR01746
56110009648	extended (e) SDRs, subgroup 1; Region: SDR_e1; cd05235
56110009649	putative NAD(P) binding site [chemical binding]; other site
56110009650	active site
56110009651	putative substrate binding site [chemical binding]; other site
56110009652	Condensation domain; Region: Condensation; pfam00668
56110009653	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110009654	Nonribosomal peptide synthase; Region: NRPS; pfam08415
56110009655	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
56110009656	acyl-activating enzyme (AAE) consensus motif; other site
56110009657	AMP binding site [chemical binding]; other site
56110009658	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009659	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
56110009660	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
56110009661	active site
56110009662	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
56110009663	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
56110009664	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009665	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
56110009666	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110009667	catalytic residue [active]
56110009668	Condensation domain; Region: Condensation; pfam00668
56110009669	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110009670	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110009671	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110009672	acyl-activating enzyme (AAE) consensus motif; other site
56110009673	AMP binding site [chemical binding]; other site
56110009674	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009675	Condensation domain; Region: Condensation; pfam00668
56110009676	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110009677	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
56110009678	acyl-activating enzyme (AAE) consensus motif; other site
56110009679	AMP binding site [chemical binding]; other site
56110009680	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009681	Condensation domain; Region: Condensation; pfam00668
56110009682	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110009683	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110009684	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110009685	acyl-activating enzyme (AAE) consensus motif; other site
56110009686	AMP binding site [chemical binding]; other site
56110009687	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009688	Condensation domain; Region: Condensation; pfam00668
56110009689	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
56110009690	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
56110009691	acyl-activating enzyme (AAE) consensus motif; other site
56110009692	AMP binding site [chemical binding]; other site
56110009693	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009694	Condensation domain; Region: Condensation; pfam00668
56110009695	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110009696	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110009697	The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116
56110009698	acyl-activating enzyme (AAE) consensus motif; other site
56110009699	AMP binding site [chemical binding]; other site
56110009700	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110009701	Condensation domain; Region: Condensation; pfam00668
56110009702	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
56110009703	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110009704	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
56110009705	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
56110009706	acyl-CoA synthetase; Validated; Region: PRK05850
56110009707	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
56110009708	acyl-activating enzyme (AAE) consensus motif; other site
56110009709	active site
56110009710	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
56110009711	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
56110009712	H+ Antiporter protein; Region: 2A0121; TIGR00900
56110009713	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110009714	putative substrate translocation pore; other site
56110009715	AMIN domain; Region: AMIN; pfam11741
56110009716	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
56110009717	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
56110009718	N-terminal plug; other site
56110009719	ligand-binding site [chemical binding]; other site
56110009720	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
56110009721	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
56110009722	intersubunit interface [polypeptide binding]; other site
56110009723	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
56110009724	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
56110009725	ABC-ATPase subunit  interface; other site
56110009726	dimer interface [polypeptide binding]; other site
56110009727	putative PBP binding regions; other site
56110009728	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
56110009729	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
56110009730	ABC-ATPase subunit  interface; other site
56110009731	dimer interface [polypeptide binding]; other site
56110009732	putative PBP binding regions; other site
56110009733	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
56110009734	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
56110009735	Walker A/P-loop; other site
56110009736	ATP binding site [chemical binding]; other site
56110009737	Q-loop/lid; other site
56110009738	ABC transporter signature motif; other site
56110009739	Walker B; other site
56110009740	D-loop; other site
56110009741	H-loop/switch region; other site
56110009742	TRX-like [2Fe-2S] Ferredoxin (Fd) family, Sucrase subfamily; composed of proteins with similarity to a novel plant enzyme, isolated from potato, which contains a Fd-like domain and exhibits sucrolytic activity. The putative active site of the Fd-like...; Region: TRX_Fd_Sucrase; cd03062
56110009743	putative dimer interface [polypeptide binding]; other site
56110009744	putative [2Fe-2S] cluster binding site [ion binding]; other site
56110009745	Penicillin amidase; Region: Penicil_amidase; pfam01804
56110009746	Cephalosporin acylase (CA) belongs to a family of beta-lactam acylases that includes penicillin G acylase (PGA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_CA; cd01936
56110009747	active site
56110009748	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
56110009749	carotene isomerase; Region: carot_isom; TIGR02730
56110009750	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110009751	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110009752	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110009753	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110009754	putative active site [active]
56110009755	putative NTP binding site [chemical binding]; other site
56110009756	putative nucleic acid binding site [nucleotide binding]; other site
56110009757	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110009758	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110009759	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110009760	active site
56110009761	SnoaL-like domain; Region: SnoaL_2; pfam12680
56110009762	NB-ARC domain; Region: NB-ARC; pfam00931
56110009763	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110009764	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110009765	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110009766	structural tetrad; other site
56110009767	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110009768	structural tetrad; other site
56110009769	glucose-1-dehydrogenase; Provisional; Region: PRK08936
56110009770	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
56110009771	NAD binding site [chemical binding]; other site
56110009772	homodimer interface [polypeptide binding]; other site
56110009773	active site
56110009774	bifunctional sterol desaturase/short chain dehydrogenase; Validated; Region: PRK07424
56110009775	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
56110009776	short chain dehydrogenase; Provisional; Region: PRK12367
56110009777	NAD(P) binding site [chemical binding]; other site
56110009778	Uncharacterized conserved protein [Function unknown]; Region: COG4748
56110009779	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
56110009780	D5 N terminal like; Region: D5_N; pfam08706
56110009781	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
56110009782	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110009783	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110009784	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110009785	putative active site [active]
56110009786	putative NTP binding site [chemical binding]; other site
56110009787	putative nucleic acid binding site [nucleotide binding]; other site
56110009788	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110009789	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110009790	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110009791	active site
56110009792	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110009793	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110009794	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110009795	putative active site [active]
56110009796	putative NTP binding site [chemical binding]; other site
56110009797	putative nucleic acid binding site [nucleotide binding]; other site
56110009798	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110009799	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110009800	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110009801	active site
56110009802	Protein of unknown function (DUF1049); Region: DUF1049; pfam06305
56110009803	aromatic acid decarboxylase; Validated; Region: PRK05920
56110009804	Flavoprotein; Region: Flavoprotein; pfam02441
56110009805	Exoribonuclease R [Transcription]; Region: VacB; COG0557
56110009806	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
56110009807	RNB domain; Region: RNB; pfam00773
56110009808	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
56110009809	RNA binding site [nucleotide binding]; other site
56110009810	Clp protease; Region: CLP_protease; pfam00574
56110009811	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
56110009812	oligomer interface [polypeptide binding]; other site
56110009813	active site residues [active]
56110009814	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
56110009815	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
56110009816	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
56110009817	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
56110009818	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
56110009819	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
56110009820	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
56110009821	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110009822	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110009823	aspartate aminotransferase; Provisional; Region: PRK05942
56110009824	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110009825	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110009826	homodimer interface [polypeptide binding]; other site
56110009827	catalytic residue [active]
56110009828	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
56110009829	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
56110009830	putative active site [active]
56110009831	metal binding site [ion binding]; metal-binding site
56110009832	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cl01898
56110009833	putative active site [active]
56110009834	Protein of function (DUF2518); Region: DUF2518; pfam10726
56110009835	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
56110009836	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
56110009837	trimerization site [polypeptide binding]; other site
56110009838	active site
56110009839	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
56110009840	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
56110009841	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110009842	HAMP domain; Region: HAMP; pfam00672
56110009843	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
56110009844	dimer interface [polypeptide binding]; other site
56110009845	phosphorylation site [posttranslational modification]
56110009846	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009847	ATP binding site [chemical binding]; other site
56110009848	Mg2+ binding site [ion binding]; other site
56110009849	G-X-G motif; other site
56110009850	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
56110009851	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
56110009852	N- and C-terminal domain interface [polypeptide binding]; other site
56110009853	active site
56110009854	MgATP binding site [chemical binding]; other site
56110009855	catalytic site [active]
56110009856	metal binding site [ion binding]; metal-binding site
56110009857	glycerol binding site [chemical binding]; other site
56110009858	homotetramer interface [polypeptide binding]; other site
56110009859	homodimer interface [polypeptide binding]; other site
56110009860	FBP binding site [chemical binding]; other site
56110009861	protein IIAGlc interface [polypeptide binding]; other site
56110009862	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
56110009863	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
56110009864	FMN binding site [chemical binding]; other site
56110009865	active site
56110009866	catalytic residues [active]
56110009867	substrate binding site [chemical binding]; other site
56110009868	AAA domain; Region: AAA_33; pfam13671
56110009869	WYL domain; Region: WYL; pfam13280
56110009870	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
56110009871	catalytic center binding site [active]
56110009872	ATP binding site [chemical binding]; other site
56110009873	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
56110009874	metal-binding site [ion binding]
56110009875	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
56110009876	dimer interface [polypeptide binding]; other site
56110009877	ADP-ribose binding site [chemical binding]; other site
56110009878	active site
56110009879	nudix motif; other site
56110009880	metal binding site [ion binding]; metal-binding site
56110009881	Fic family protein [Function unknown]; Region: COG3177
56110009882	Fic/DOC family; Region: Fic; pfam02661
56110009883	deoxyribodipyrimidine photo-lyase, 8-HDF type; Region: photolyase_8HDF; TIGR03556
56110009884	DNA photolyase; Region: DNA_photolyase; pfam00875
56110009885	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110009886	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110009887	NAD(P) binding site [chemical binding]; other site
56110009888	active site
56110009889	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
56110009890	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
56110009891	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
56110009892	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
56110009893	HicB family; Region: HicB; pfam05534
56110009894	PemK-like protein; Region: PemK; pfam02452
56110009895	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110009896	dimerization interface [polypeptide binding]; other site
56110009897	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009898	putative active site [active]
56110009899	heme pocket [chemical binding]; other site
56110009900	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009901	dimer interface [polypeptide binding]; other site
56110009902	phosphorylation site [posttranslational modification]
56110009903	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009904	ATP binding site [chemical binding]; other site
56110009905	Mg2+ binding site [ion binding]; other site
56110009906	G-X-G motif; other site
56110009907	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110009908	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110009909	active site
56110009910	phosphorylation site [posttranslational modification]
56110009911	intermolecular recognition site; other site
56110009912	dimerization interface [polypeptide binding]; other site
56110009913	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110009914	DNA binding site [nucleotide binding]
56110009915	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009916	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110009917	putative active site [active]
56110009918	heme pocket [chemical binding]; other site
56110009919	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009920	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110009921	putative active site [active]
56110009922	heme pocket [chemical binding]; other site
56110009923	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009924	putative active site [active]
56110009925	heme pocket [chemical binding]; other site
56110009926	hypothetical protein; Provisional; Region: PRK13560
56110009927	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009928	putative active site [active]
56110009929	heme pocket [chemical binding]; other site
56110009930	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110009931	putative active site [active]
56110009932	heme pocket [chemical binding]; other site
56110009933	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110009934	dimer interface [polypeptide binding]; other site
56110009935	phosphorylation site [posttranslational modification]
56110009936	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110009937	ATP binding site [chemical binding]; other site
56110009938	Mg2+ binding site [ion binding]; other site
56110009939	G-X-G motif; other site
56110009940	Cytochrome c; Region: Cytochrom_C; cl11414
56110009941	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
56110009942	Fatty acid desaturase; Region: FA_desaturase; pfam00487
56110009943	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
56110009944	putative di-iron ligands [ion binding]; other site
56110009945	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
56110009946	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
56110009947	active site
56110009948	catalytic tetrad [active]
56110009949	SnoaL-like domain; Region: SnoaL_3; pfam13474
56110009950	SnoaL-like domain; Region: SnoaL_2; pfam12680
56110009951	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
56110009952	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
56110009953	oligomeric interface; other site
56110009954	putative active site [active]
56110009955	homodimer interface [polypeptide binding]; other site
56110009956	N-terminal putative catalytic domain of uncharacterized HKD family nucleases fused to putative helicases from the Snf2-like family; Region: PLDc_N_Snf2_like; cd09178
56110009957	PLD-like domain; Region: PLDc_2; pfam13091
56110009958	putative homodimer interface [polypeptide binding]; other site
56110009959	putative active site [active]
56110009960	catalytic site [active]
56110009961	DEAD-like helicases superfamily; Region: DEXDc; smart00487
56110009962	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110009963	ATP binding site [chemical binding]; other site
56110009964	putative Mg++ binding site [ion binding]; other site
56110009965	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110009966	nucleotide binding region [chemical binding]; other site
56110009967	ATP-binding site [chemical binding]; other site
56110009968	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
56110009969	RNA polymerase sigma factor, cyanobacterial RpoD-like family; Region: Sig70-cyanoRpoD; TIGR02997
56110009970	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110009971	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
56110009972	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110009973	DNA binding residues [nucleotide binding]
56110009974	Domain of unknown function (DUF3854); Region: DUF3854; pfam12965
56110009975	D5 N terminal like; Region: D5_N; smart00885
56110009976	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
56110009977	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
56110009978	active site
56110009979	catalytic residues [active]
56110009980	DNA binding site [nucleotide binding]
56110009981	Int/Topo IB signature motif; other site
56110009982	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
56110009983	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
56110009984	ring oligomerisation interface [polypeptide binding]; other site
56110009985	ATP/Mg binding site [chemical binding]; other site
56110009986	stacking interactions; other site
56110009987	hinge regions; other site
56110009988	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110009989	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
56110009990	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110009991	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110009992	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
56110009993	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110009994	Protein kinase domain; Region: Pkinase; pfam00069
56110009995	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110009996	active site
56110009997	ATP binding site [chemical binding]; other site
56110009998	substrate binding site [chemical binding]; other site
56110009999	activation loop (A-loop); other site
56110010000	AAA ATPase domain; Region: AAA_16; pfam13191
56110010001	Predicted ATPase [General function prediction only]; Region: COG3899
56110010002	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010003	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010004	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110010005	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010006	ATP binding site [chemical binding]; other site
56110010007	Mg2+ binding site [ion binding]; other site
56110010008	G-X-G motif; other site
56110010009	Domain of unknown function (DUF1830); Region: DUF1830; pfam08865
56110010010	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
56110010011	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
56110010012	NAD(P) binding site [chemical binding]; other site
56110010013	homotetramer interface [polypeptide binding]; other site
56110010014	homodimer interface [polypeptide binding]; other site
56110010015	active site
56110010016	Repair protein; Region: Repair_PSII; pfam04536
56110010017	Domain of unknown function (DUF4346); Region: DUF4346; pfam14251
56110010018	sucrose-phosphate synthase, putative, glycosyltransferase domain; Region: sucr_P_syn_N; TIGR02472
56110010019	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
56110010020	putative ADP-binding pocket [chemical binding]; other site
56110010021	aspartate kinase; Provisional; Region: PRK07431
56110010022	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
56110010023	putative nucleotide binding site [chemical binding]; other site
56110010024	putative catalytic residues [active]
56110010025	putative Mg ion binding site [ion binding]; other site
56110010026	putative aspartate binding site [chemical binding]; other site
56110010027	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
56110010028	putative allosteric regulatory site; other site
56110010029	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
56110010030	putative allosteric regulatory residue; other site
56110010031	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
56110010032	putative allosteric regulatory site; other site
56110010033	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
56110010034	putative allosteric regulatory residue; other site
56110010035	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
56110010036	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
56110010037	putative active site [active]
56110010038	oxyanion strand; other site
56110010039	catalytic triad [active]
56110010040	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cl00237
56110010041	putative substrate binding pocket [chemical binding]; other site
56110010042	catalytic triad [active]
56110010043	AB domain interface; other site
56110010044	Uncharacterized conserved protein [Function unknown]; Region: COG2308
56110010045	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
56110010046	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
56110010047	Predicted proteasome-type protease [Posttranslational modification, protein turnover, chaperones]; Region: COG3484
56110010048	Bacterial proteasome, beta subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; Region: proteasome_beta_bacterial; cd03765
56110010049	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110010050	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010051	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010052	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010053	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
56110010054	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
56110010055	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110010056	non-specific DNA binding site [nucleotide binding]; other site
56110010057	salt bridge; other site
56110010058	sequence-specific DNA binding site [nucleotide binding]; other site
56110010059	Domain of unknown function (DUF955); Region: DUF955; pfam06114
56110010060	Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890
56110010061	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110010062	S-adenosylmethionine binding site [chemical binding]; other site
56110010063	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
56110010064	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110010065	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
56110010066	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110010067	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110010068	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
56110010069	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
56110010070	homotetramer interface [polypeptide binding]; other site
56110010071	ligand binding site [chemical binding]; other site
56110010072	catalytic site [active]
56110010073	NAD binding site [chemical binding]; other site
56110010074	Uncharacterized ABC-type transport system, permease components [General function prediction only]; Region: COG3932
56110010075	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
56110010076	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110010077	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
56110010078	cofactor binding site; other site
56110010079	DNA binding site [nucleotide binding]
56110010080	substrate interaction site [chemical binding]; other site
56110010081	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
56110010082	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
56110010083	FtsX-like permease family; Region: FtsX; pfam02687
56110010084	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
56110010085	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
56110010086	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110010087	Predicted transcriptional regulators [Transcription]; Region: COG1510
56110010088	MarR family; Region: MarR; pfam01047
56110010089	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
56110010090	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
56110010091	Protein of unknown function (DUF1517); Region: DUF1517; cl01807
56110010092	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110010093	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010094	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010095	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010096	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010097	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010098	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010099	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010100	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010101	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110010102	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010103	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010104	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010105	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010106	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010107	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010108	arogenate dehydrogenase; Reviewed; Region: PRK07417
56110010109	prephenate dehydrogenase; Validated; Region: PRK08507
56110010110	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
56110010111	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
56110010112	Protein of unknown function (DUF2839); Region: DUF2839; pfam10999
56110010113	Domain of unknown function (DUF1815); Region: DUF1815; pfam08844
56110010114	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110010115	Creatinine amidohydrolase; Region: Creatininase; pfam02633
56110010116	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010117	GAF domain; Region: GAF; pfam01590
56110010118	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010119	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010120	His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388
56110010121	dimer interface [polypeptide binding]; other site
56110010122	phosphorylation site [posttranslational modification]
56110010123	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010124	ATP binding site [chemical binding]; other site
56110010125	G-X-G motif; other site
56110010126	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
56110010127	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110010128	Coenzyme A binding pocket [chemical binding]; other site
56110010129	L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434
56110010130	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
56110010131	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
56110010132	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
56110010133	ABC-ATPase subunit  interface; other site
56110010134	dimer interface [polypeptide binding]; other site
56110010135	putative PBP binding regions; other site
56110010136	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
56110010137	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
56110010138	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
56110010139	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
56110010140	intersubunit interface [polypeptide binding]; other site
56110010141	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
56110010142	dimer interface [polypeptide binding]; other site
56110010143	active site
56110010144	aspartate-rich active site metal binding site; other site
56110010145	allosteric magnesium binding site [ion binding]; other site
56110010146	Schiff base residues; other site
56110010147	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
56110010148	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
56110010149	P-loop, Walker A motif; other site
56110010150	Base recognition motif; other site
56110010151	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
56110010152	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110010153	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110010154	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110010155	structural tetrad; other site
56110010156	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
56110010157	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
56110010158	homodecamer interface [polypeptide binding]; other site
56110010159	GTP cyclohydrolase I; Provisional; Region: PLN03044
56110010160	active site
56110010161	putative catalytic site residues [active]
56110010162	zinc binding site [ion binding]; other site
56110010163	GTP-CH-I/GFRP interaction surface; other site
56110010164	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
56110010165	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
56110010166	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
56110010167	Putative restriction endonuclease; Region: Uma2; pfam05685
56110010168	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
56110010169	FeoA domain; Region: FeoA; pfam04023
56110010170	FeoA domain; Region: FeoA; pfam04023
56110010171	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
56110010172	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
56110010173	G1 box; other site
56110010174	GTP/Mg2+ binding site [chemical binding]; other site
56110010175	Switch I region; other site
56110010176	G2 box; other site
56110010177	G3 box; other site
56110010178	Switch II region; other site
56110010179	G4 box; other site
56110010180	G5 box; other site
56110010181	Nucleoside recognition; Region: Gate; pfam07670
56110010182	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
56110010183	FeoC like transcriptional regulator; Region: FeoC; pfam09012
56110010184	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
56110010185	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
56110010186	Soluble P-type ATPase [General function prediction only]; Region: COG4087
56110010187	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
56110010188	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110010189	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010190	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010191	active site
56110010192	phosphorylation site [posttranslational modification]
56110010193	intermolecular recognition site; other site
56110010194	dimerization interface [polypeptide binding]; other site
56110010195	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110010196	active site
56110010197	ATP binding site [chemical binding]; other site
56110010198	substrate binding site [chemical binding]; other site
56110010199	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110010200	activation loop (A-loop); other site
56110010201	AAA ATPase domain; Region: AAA_16; pfam13191
56110010202	Predicted ATPase [General function prediction only]; Region: COG3899
56110010203	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010204	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010205	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110010206	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010207	putative active site [active]
56110010208	heme pocket [chemical binding]; other site
56110010209	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010210	dimer interface [polypeptide binding]; other site
56110010211	phosphorylation site [posttranslational modification]
56110010212	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010213	ATP binding site [chemical binding]; other site
56110010214	Mg2+ binding site [ion binding]; other site
56110010215	G-X-G motif; other site
56110010216	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010217	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010218	active site
56110010219	phosphorylation site [posttranslational modification]
56110010220	intermolecular recognition site; other site
56110010221	dimerization interface [polypeptide binding]; other site
56110010222	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010223	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110010224	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110010225	active site
56110010226	ATP binding site [chemical binding]; other site
56110010227	substrate binding site [chemical binding]; other site
56110010228	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110010229	substrate binding site [chemical binding]; other site
56110010230	activation loop (A-loop); other site
56110010231	activation loop (A-loop); other site
56110010232	AAA ATPase domain; Region: AAA_16; pfam13191
56110010233	Predicted ATPase [General function prediction only]; Region: COG3899
56110010234	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010235	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010236	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110010237	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010238	putative active site [active]
56110010239	heme pocket [chemical binding]; other site
56110010240	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010241	dimer interface [polypeptide binding]; other site
56110010242	phosphorylation site [posttranslational modification]
56110010243	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010244	ATP binding site [chemical binding]; other site
56110010245	Mg2+ binding site [ion binding]; other site
56110010246	G-X-G motif; other site
56110010247	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010248	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010249	active site
56110010250	phosphorylation site [posttranslational modification]
56110010251	intermolecular recognition site; other site
56110010252	dimerization interface [polypeptide binding]; other site
56110010253	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010254	phosphorylation site [posttranslational modification]
56110010255	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010256	GAF domain; Region: GAF; pfam01590
56110010257	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010258	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010259	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110010260	His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388
56110010261	dimer interface [polypeptide binding]; other site
56110010262	phosphorylation site [posttranslational modification]
56110010263	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010264	ATP binding site [chemical binding]; other site
56110010265	Mg2+ binding site [ion binding]; other site
56110010266	G-X-G motif; other site
56110010267	RNA polymerase sigma factor; Provisional; Region: PRK12518
56110010268	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110010269	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110010270	DNA binding residues [nucleotide binding]
56110010271	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
56110010272	dimer interface [polypeptide binding]; other site
56110010273	Protein of unknown function (DUF1611); Region: DUF1611; pfam07755
56110010274	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
56110010275	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
56110010276	active site
56110010277	Chlorophyll A-B binding protein; Region: Chloroa_b-bind; cl02879
56110010278	succinate dehydrogenase iron-sulfur subunit; Provisional; Region: PRK12577
56110010279	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
56110010280	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010281	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010282	active site
56110010283	phosphorylation site [posttranslational modification]
56110010284	intermolecular recognition site; other site
56110010285	dimerization interface [polypeptide binding]; other site
56110010286	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
56110010287	dimer interface [polypeptide binding]; other site
56110010288	phosphorylation site [posttranslational modification]
56110010289	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010290	ATP binding site [chemical binding]; other site
56110010291	Mg2+ binding site [ion binding]; other site
56110010292	G-X-G motif; other site
56110010293	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010294	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010295	active site
56110010296	phosphorylation site [posttranslational modification]
56110010297	intermolecular recognition site; other site
56110010298	dimerization interface [polypeptide binding]; other site
56110010299	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110010300	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110010301	metal binding site [ion binding]; metal-binding site
56110010302	active site
56110010303	I-site; other site
56110010304	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010305	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010306	active site
56110010307	phosphorylation site [posttranslational modification]
56110010308	intermolecular recognition site; other site
56110010309	dimerization interface [polypeptide binding]; other site
56110010310	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010311	dimer interface [polypeptide binding]; other site
56110010312	phosphorylation site [posttranslational modification]
56110010313	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010314	ATP binding site [chemical binding]; other site
56110010315	Mg2+ binding site [ion binding]; other site
56110010316	G-X-G motif; other site
56110010317	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010318	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010319	active site
56110010320	phosphorylation site [posttranslational modification]
56110010321	intermolecular recognition site; other site
56110010322	dimerization interface [polypeptide binding]; other site
56110010323	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010324	GAF domain; Region: GAF; pfam01590
56110010325	PAS domain S-box; Region: sensory_box; TIGR00229
56110010326	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010327	putative active site [active]
56110010328	heme pocket [chemical binding]; other site
56110010329	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010330	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010331	PAS domain S-box; Region: sensory_box; TIGR00229
56110010332	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010333	putative active site [active]
56110010334	heme pocket [chemical binding]; other site
56110010335	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010336	GAF domain; Region: GAF; pfam01590
56110010337	PAS fold; Region: PAS_4; pfam08448
56110010338	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010339	putative active site [active]
56110010340	heme pocket [chemical binding]; other site
56110010341	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110010342	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010343	putative active site [active]
56110010344	heme pocket [chemical binding]; other site
56110010345	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010346	putative active site [active]
56110010347	heme pocket [chemical binding]; other site
56110010348	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010349	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010350	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010351	dimer interface [polypeptide binding]; other site
56110010352	phosphorylation site [posttranslational modification]
56110010353	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010354	ATP binding site [chemical binding]; other site
56110010355	Mg2+ binding site [ion binding]; other site
56110010356	G-X-G motif; other site
56110010357	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010358	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010359	active site
56110010360	phosphorylation site [posttranslational modification]
56110010361	intermolecular recognition site; other site
56110010362	dimerization interface [polypeptide binding]; other site
56110010363	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
56110010364	NlpC/P60 family; Region: NLPC_P60; pfam00877
56110010365	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110010366	anti sigma factor interaction site; other site
56110010367	regulatory phosphorylation site [posttranslational modification]; other site
56110010368	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
56110010369	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110010370	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
56110010371	gamma-beta subunit interface [polypeptide binding]; other site
56110010372	alpha-beta subunit interface [polypeptide binding]; other site
56110010373	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
56110010374	alpha-gamma subunit interface [polypeptide binding]; other site
56110010375	beta-gamma subunit interface [polypeptide binding]; other site
56110010376	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
56110010377	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
56110010378	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
56110010379	Walker A/P-loop; other site
56110010380	ATP binding site [chemical binding]; other site
56110010381	Q-loop/lid; other site
56110010382	ABC transporter signature motif; other site
56110010383	Walker B; other site
56110010384	D-loop; other site
56110010385	H-loop/switch region; other site
56110010386	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
56110010387	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
56110010388	Walker A/P-loop; other site
56110010389	ATP binding site [chemical binding]; other site
56110010390	Q-loop/lid; other site
56110010391	ABC transporter signature motif; other site
56110010392	Walker B; other site
56110010393	D-loop; other site
56110010394	H-loop/switch region; other site
56110010395	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
56110010396	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
56110010397	TM-ABC transporter signature motif; other site
56110010398	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
56110010399	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
56110010400	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
56110010401	TM-ABC transporter signature motif; other site
56110010402	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
56110010403	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
56110010404	putative ligand binding site [chemical binding]; other site
56110010405	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
56110010406	G1 box; other site
56110010407	GTP/Mg2+ binding site [chemical binding]; other site
56110010408	G2 box; other site
56110010409	Switch I region; other site
56110010410	G3 box; other site
56110010411	Switch II region; other site
56110010412	G4 box; other site
56110010413	G5 box; other site
56110010414	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
56110010415	UreF; Region: UreF; pfam01730
56110010416	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
56110010417	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
56110010418	dimer interface [polypeptide binding]; other site
56110010419	catalytic residues [active]
56110010420	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110010421	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110010422	dimerization interface [polypeptide binding]; other site
56110010423	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010424	dimer interface [polypeptide binding]; other site
56110010425	phosphorylation site [posttranslational modification]
56110010426	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010427	ATP binding site [chemical binding]; other site
56110010428	Mg2+ binding site [ion binding]; other site
56110010429	G-X-G motif; other site
56110010430	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110010431	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110010432	metal binding site [ion binding]; metal-binding site
56110010433	active site
56110010434	I-site; other site
56110010435	GST_N family, unknown subfamily 4; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_4; cd03056
56110010436	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
56110010437	putative C-terminal domain interface [polypeptide binding]; other site
56110010438	putative GSH binding site (G-site) [chemical binding]; other site
56110010439	putative dimer interface [polypeptide binding]; other site
56110010440	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
56110010441	N-terminal domain interface [polypeptide binding]; other site
56110010442	dimer interface [polypeptide binding]; other site
56110010443	substrate binding pocket (H-site) [chemical binding]; other site
56110010444	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110010445	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110010446	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
56110010447	protein binding site [polypeptide binding]; other site
56110010448	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
56110010449	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Region: LPLAT_MGAT-like; cd07987
56110010450	putative acyl-acceptor binding pocket; other site
56110010451	DNA polymerase III, alpha subunit (gram-positive type) [DNA replication, recombination, and repair]; Region: PolC; COG2176
56110010452	Uncharacterized conserved protein [Function unknown]; Region: COG3937
56110010453	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
56110010454	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
56110010455	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110010456	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
56110010457	cofactor binding site; other site
56110010458	DNA binding site [nucleotide binding]
56110010459	substrate interaction site [chemical binding]; other site
56110010460	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
56110010461	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110010462	Walker A motif; other site
56110010463	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110010464	protein-splicing catalytic site; other site
56110010465	thioester formation/cholesterol transfer; other site
56110010466	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110010467	non-specific DNA binding site [nucleotide binding]; other site
56110010468	salt bridge; other site
56110010469	sequence-specific DNA binding site [nucleotide binding]; other site
56110010470	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110010471	protein-splicing catalytic site; other site
56110010472	replicative DNA helicase; Region: DnaB; TIGR00665
56110010473	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
56110010474	ATP binding site [chemical binding]; other site
56110010475	Walker B motif; other site
56110010476	DNA binding loops [nucleotide binding]
56110010477	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
56110010478	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
56110010479	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
56110010480	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
56110010481	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
56110010482	Beta-lactamase; Region: Beta-lactamase; pfam00144
56110010483	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2402
56110010484	Amino acid permease; Region: AA_permease_2; pfam13520
56110010485	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010486	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110010487	putative active site [active]
56110010488	heme pocket [chemical binding]; other site
56110010489	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010490	dimer interface [polypeptide binding]; other site
56110010491	phosphorylation site [posttranslational modification]
56110010492	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010493	ATP binding site [chemical binding]; other site
56110010494	Mg2+ binding site [ion binding]; other site
56110010495	G-X-G motif; other site
56110010496	Uncharacterized conserved protein [Function unknown]; Region: COG2433
56110010497	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010498	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110010499	binding surface
56110010500	TPR motif; other site
56110010501	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010502	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110010503	TPR motif; other site
56110010504	binding surface
56110010505	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010506	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010507	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110010508	TPR motif; other site
56110010509	binding surface
56110010510	TPR repeat; Region: TPR_11; pfam13414
56110010511	CHAT domain; Region: CHAT; pfam12770
56110010512	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; pfam04014
56110010513	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110010514	putative active site [active]
56110010515	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
56110010516	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110010517	putative active site [active]
56110010518	Cupin domain; Region: Cupin_2; cl17218
56110010519	Macrolide 2'-Phosphotransferase (MPH2'). MPH2' is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase; Region: MPH2' cd05152
56110010520	Phosphotransferase enzyme family; Region: APH; pfam01636
56110010521	putative active site [active]
56110010522	putative substrate binding site [chemical binding]; other site
56110010523	ATP binding site [chemical binding]; other site
56110010524	Bacterial Ig-like domain; Region: Big_5; pfam13205
56110010525	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
56110010526	MG2 domain; Region: A2M_N; pfam01835
56110010527	Alpha-2-macroglobulin family; Region: A2M; pfam00207
56110010528	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
56110010529	surface patch; other site
56110010530	specificity defining residues; other site
56110010531	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
56110010532	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
56110010533	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
56110010534	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
56110010535	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010536	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010537	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010538	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010539	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110010540	TPR motif; other site
56110010541	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010542	binding surface
56110010543	Tetratricopeptide repeat; Region: TPR_10; pfam13374
56110010544	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010545	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110010546	binding surface
56110010547	TPR motif; other site
56110010548	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110010549	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
56110010550	active site
56110010551	catalytic triad [active]
56110010552	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110010553	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
56110010554	Walker A motif; other site
56110010555	ATP binding site [chemical binding]; other site
56110010556	Walker B motif; other site
56110010557	arginine finger; other site
56110010558	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
56110010559	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
56110010560	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
56110010561	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
56110010562	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
56110010563	recombination protein RecR; Reviewed; Region: recR; PRK00076
56110010564	Helix-hairpin-helix DNA-binding motif class 1; Region: HhH1; smart00278
56110010565	RecR protein; Region: RecR; pfam02132
56110010566	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
56110010567	putative active site [active]
56110010568	putative metal-binding site [ion binding]; other site
56110010569	tetramer interface [polypeptide binding]; other site
56110010570	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
56110010571	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
56110010572	ligand binding site [chemical binding]; other site
56110010573	Gram-negative bacterial tonB protein; Region: TonB; cl10048
56110010574	Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075
56110010575	PGAP1-like protein; Region: PGAP1; pfam07819
56110010576	Predicted permease, cadmium resistance protein [Inorganic ion transport and metabolism]; Region: CadD; COG4300
56110010577	Cadmium resistance transporter; Region: Cad; pfam03596
56110010578	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
56110010579	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
56110010580	TrkA-N domain; Region: TrkA_N; pfam02254
56110010581	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110010582	active site
56110010583	Predicted membrane protein [Function unknown]; Region: COG2324
56110010584	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996
56110010585	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110010586	Coenzyme A binding pocket [chemical binding]; other site
56110010587	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
56110010588	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cl00257
56110010589	IHF - DNA interface [nucleotide binding]; other site
56110010590	IHF dimer interface [polypeptide binding]; other site
56110010591	Major Facilitator Superfamily; Region: MFS_1; pfam07690
56110010592	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110010593	putative substrate translocation pore; other site
56110010594	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
56110010595	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
56110010596	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
56110010597	metal binding site [ion binding]; metal-binding site
56110010598	glutamate-1-semialdehyde 2,1-aminomutase; Region: PLN02482
56110010599	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
56110010600	inhibitor-cofactor binding pocket; inhibition site
56110010601	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110010602	catalytic residue [active]
56110010603	SnoaL-like domain; Region: SnoaL_3; pfam13474
56110010604	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010605	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010606	active site
56110010607	phosphorylation site [posttranslational modification]
56110010608	intermolecular recognition site; other site
56110010609	dimerization interface [polypeptide binding]; other site
56110010610	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010611	dimer interface [polypeptide binding]; other site
56110010612	phosphorylation site [posttranslational modification]
56110010613	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010614	ATP binding site [chemical binding]; other site
56110010615	Mg2+ binding site [ion binding]; other site
56110010616	G-X-G motif; other site
56110010617	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010618	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010619	active site
56110010620	phosphorylation site [posttranslational modification]
56110010621	intermolecular recognition site; other site
56110010622	dimerization interface [polypeptide binding]; other site
56110010623	PAS fold; Region: PAS_3; pfam08447
56110010624	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010625	putative active site [active]
56110010626	heme pocket [chemical binding]; other site
56110010627	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010628	GAF domain; Region: GAF; pfam01590
56110010629	PAS domain S-box; Region: sensory_box; TIGR00229
56110010630	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010631	putative active site [active]
56110010632	heme pocket [chemical binding]; other site
56110010633	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110010634	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010635	putative active site [active]
56110010636	heme pocket [chemical binding]; other site
56110010637	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010638	dimer interface [polypeptide binding]; other site
56110010639	phosphorylation site [posttranslational modification]
56110010640	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010641	ATP binding site [chemical binding]; other site
56110010642	Mg2+ binding site [ion binding]; other site
56110010643	G-X-G motif; other site
56110010644	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110010645	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010646	active site
56110010647	phosphorylation site [posttranslational modification]
56110010648	intermolecular recognition site; other site
56110010649	dimerization interface [polypeptide binding]; other site
56110010650	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110010651	active site
56110010652	ATP binding site [chemical binding]; other site
56110010653	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110010654	substrate binding site [chemical binding]; other site
56110010655	activation loop (A-loop); other site
56110010656	AAA ATPase domain; Region: AAA_16; pfam13191
56110010657	Predicted ATPase [General function prediction only]; Region: COG3899
56110010658	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010659	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010660	PAS fold; Region: PAS_4; pfam08448
56110010661	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010662	putative active site [active]
56110010663	heme pocket [chemical binding]; other site
56110010664	PAS domain S-box; Region: sensory_box; TIGR00229
56110010665	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010666	putative active site [active]
56110010667	heme pocket [chemical binding]; other site
56110010668	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010669	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110010670	putative active site [active]
56110010671	heme pocket [chemical binding]; other site
56110010672	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
56110010673	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010674	PAS fold; Region: PAS_3; pfam08447
56110010675	putative active site [active]
56110010676	heme pocket [chemical binding]; other site
56110010677	PAS domain S-box; Region: sensory_box; TIGR00229
56110010678	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010679	putative active site [active]
56110010680	heme pocket [chemical binding]; other site
56110010681	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010682	dimer interface [polypeptide binding]; other site
56110010683	phosphorylation site [posttranslational modification]
56110010684	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010685	ATP binding site [chemical binding]; other site
56110010686	Mg2+ binding site [ion binding]; other site
56110010687	G-X-G motif; other site
56110010688	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010689	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010690	active site
56110010691	phosphorylation site [posttranslational modification]
56110010692	intermolecular recognition site; other site
56110010693	dimerization interface [polypeptide binding]; other site
56110010694	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110010695	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010696	active site
56110010697	phosphorylation site [posttranslational modification]
56110010698	intermolecular recognition site; other site
56110010699	dimerization interface [polypeptide binding]; other site
56110010700	PAS domain S-box; Region: sensory_box; TIGR00229
56110010701	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010702	putative active site [active]
56110010703	heme pocket [chemical binding]; other site
56110010704	PAS fold; Region: PAS; pfam00989
56110010705	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010706	putative active site [active]
56110010707	heme pocket [chemical binding]; other site
56110010708	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010709	PAS fold; Region: PAS_3; pfam08447
56110010710	putative active site [active]
56110010711	heme pocket [chemical binding]; other site
56110010712	PAS domain S-box; Region: sensory_box; TIGR00229
56110010713	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010714	putative active site [active]
56110010715	heme pocket [chemical binding]; other site
56110010716	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110010717	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010718	putative active site [active]
56110010719	heme pocket [chemical binding]; other site
56110010720	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010721	dimer interface [polypeptide binding]; other site
56110010722	phosphorylation site [posttranslational modification]
56110010723	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010724	ATP binding site [chemical binding]; other site
56110010725	Mg2+ binding site [ion binding]; other site
56110010726	G-X-G motif; other site
56110010727	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110010728	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010729	active site
56110010730	phosphorylation site [posttranslational modification]
56110010731	intermolecular recognition site; other site
56110010732	dimerization interface [polypeptide binding]; other site
56110010733	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110010734	DNA binding site [nucleotide binding]
56110010735	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
56110010736	putative binding surface; other site
56110010737	active site
56110010738	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010739	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010740	active site
56110010741	phosphorylation site [posttranslational modification]
56110010742	intermolecular recognition site; other site
56110010743	dimerization interface [polypeptide binding]; other site
56110010744	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010745	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010746	active site
56110010747	phosphorylation site [posttranslational modification]
56110010748	intermolecular recognition site; other site
56110010749	dimerization interface [polypeptide binding]; other site
56110010750	Coenzyme Q (ubiquinone) biosynthesis protein Coq4; Region: Coq4; cl02093
56110010751	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
56110010752	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110010753	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110010754	putative active site [active]
56110010755	antitoxin MqsA for MqsR toxin; Region: MqsA; cl15819
56110010756	toxin interface [polypeptide binding]; other site
56110010757	Zn binding site [ion binding]; other site
56110010758	Superfamily II helicase [General function prediction only]; Region: COG1204
56110010759	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110010760	ATP binding site [chemical binding]; other site
56110010761	putative Mg++ binding site [ion binding]; other site
56110010762	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
56110010763	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
56110010764	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
56110010765	active site
56110010766	dimer interface [polypeptide binding]; other site
56110010767	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
56110010768	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
56110010769	active site
56110010770	FMN binding site [chemical binding]; other site
56110010771	substrate binding site [chemical binding]; other site
56110010772	3Fe-4S cluster binding site [ion binding]; other site
56110010773	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
56110010774	domain interface; other site
56110010775	Protein of unknown function (DUF433); Region: DUF433; pfam04255
56110010776	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
56110010777	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DinB; COG2318
56110010778	DinB superfamily; Region: DinB_2; pfam12867
56110010779	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
56110010780	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
56110010781	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
56110010782	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010783	PAS domain; Region: PAS_9; pfam13426
56110010784	putative active site [active]
56110010785	heme pocket [chemical binding]; other site
56110010786	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010787	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010788	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010789	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110010790	putative active site [active]
56110010791	heme pocket [chemical binding]; other site
56110010792	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010793	putative active site [active]
56110010794	heme pocket [chemical binding]; other site
56110010795	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110010796	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010797	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010798	PAS fold; Region: PAS_3; pfam08447
56110010799	putative active site [active]
56110010800	heme pocket [chemical binding]; other site
56110010801	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110010802	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110010803	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010804	dimer interface [polypeptide binding]; other site
56110010805	phosphorylation site [posttranslational modification]
56110010806	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010807	ATP binding site [chemical binding]; other site
56110010808	Mg2+ binding site [ion binding]; other site
56110010809	G-X-G motif; other site
56110010810	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110010811	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010812	active site
56110010813	phosphorylation site [posttranslational modification]
56110010814	intermolecular recognition site; other site
56110010815	dimerization interface [polypeptide binding]; other site
56110010816	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010817	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010818	active site
56110010819	phosphorylation site [posttranslational modification]
56110010820	intermolecular recognition site; other site
56110010821	dimerization interface [polypeptide binding]; other site
56110010822	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110010823	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110010824	metal binding site [ion binding]; metal-binding site
56110010825	active site
56110010826	I-site; other site
56110010827	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110010828	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110010829	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110010830	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110010831	putative active site [active]
56110010832	putative NTP binding site [chemical binding]; other site
56110010833	putative nucleic acid binding site [nucleotide binding]; other site
56110010834	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110010835	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110010836	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110010837	active site
56110010838	Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; Region: PRX_like2; cd02970
56110010839	putative catalytic residues [active]
56110010840	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
56110010841	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
56110010842	dimer interface [polypeptide binding]; other site
56110010843	decamer (pentamer of dimers) interface [polypeptide binding]; other site
56110010844	catalytic triad [active]
56110010845	peroxidatic and resolving cysteines [active]
56110010846	CHASE4 domain; Region: CHASE4; pfam05228
56110010847	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110010848	dimerization interface [polypeptide binding]; other site
56110010849	PAS domain S-box; Region: sensory_box; TIGR00229
56110010850	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110010851	putative active site [active]
56110010852	heme pocket [chemical binding]; other site
56110010853	GAF domain; Region: GAF_3; pfam13492
56110010854	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110010855	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110010856	dimer interface [polypeptide binding]; other site
56110010857	phosphorylation site [posttranslational modification]
56110010858	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110010859	ATP binding site [chemical binding]; other site
56110010860	Mg2+ binding site [ion binding]; other site
56110010861	G-X-G motif; other site
56110010862	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010863	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010864	active site
56110010865	phosphorylation site [posttranslational modification]
56110010866	intermolecular recognition site; other site
56110010867	dimerization interface [polypeptide binding]; other site
56110010868	Response regulator receiver domain; Region: Response_reg; pfam00072
56110010869	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010870	active site
56110010871	phosphorylation site [posttranslational modification]
56110010872	intermolecular recognition site; other site
56110010873	dimerization interface [polypeptide binding]; other site
56110010874	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110010875	putative binding surface; other site
56110010876	active site
56110010877	carotene isomerase; Region: carot_isom; TIGR02730
56110010878	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110010879	RAB proteins geranylgeranyltransferase component A (RAB escort protein) [Posttranslational modification, protein turnover, chaperones]; Region: MRS6; cl17678
56110010880	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010881	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110010882	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010883	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010884	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010885	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110010886	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
56110010887	ParB-like nuclease domain; Region: ParBc; pfam02195
56110010888	ribonuclease E; Reviewed; Region: rne; PRK10811
56110010889	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
56110010890	Chain length determinant protein; Region: Wzz; pfam02706
56110010891	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
56110010892	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110010893	Magnesium ion binding site [ion binding]; other site
56110010894	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110010895	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110010896	NAD(P) binding site [chemical binding]; other site
56110010897	active site
56110010898	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110010899	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
56110010900	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110010901	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110010902	Walker A/P-loop; other site
56110010903	ATP binding site [chemical binding]; other site
56110010904	Q-loop/lid; other site
56110010905	ABC transporter signature motif; other site
56110010906	Walker B; other site
56110010907	D-loop; other site
56110010908	H-loop/switch region; other site
56110010909	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
56110010910	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
56110010911	substrate binding site; other site
56110010912	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
56110010913	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
56110010914	NAD binding site [chemical binding]; other site
56110010915	homotetramer interface [polypeptide binding]; other site
56110010916	homodimer interface [polypeptide binding]; other site
56110010917	substrate binding site [chemical binding]; other site
56110010918	active site
56110010919	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
56110010920	Putative zinc binding domain; Region: Methyltransf_13; pfam08421
56110010921	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110010922	Methyltransferase domain; Region: Methyltransf_12; pfam08242
56110010923	C-methyltransferase C-terminal domain; Region: Methyltransf_14; pfam08484
56110010924	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110010925	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
56110010926	NAD(P) binding site [chemical binding]; other site
56110010927	active site
56110010928	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110010929	Methyltransferase domain; Region: Methyltransf_12; pfam08242
56110010930	C-methyltransferase C-terminal domain; Region: Methyltransf_14; pfam08484
56110010931	Cephalosporin hydroxylase; Region: CmcI; pfam04989
56110010932	Transposase [DNA replication, recombination, and repair]; Region: COG5421
56110010933	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110010934	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110010935	active site
56110010936	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110010937	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110010938	active site
56110010939	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110010940	This family is most closely related to the GT1 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis; Region: GT1_WbnK_like; cd03807
56110010941	putative ADP-binding pocket [chemical binding]; other site
56110010942	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
56110010943	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
56110010944	active site
56110010945	dimer interface [polypeptide binding]; other site
56110010946	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
56110010947	Ligand Binding Site [chemical binding]; other site
56110010948	Molecular Tunnel; other site
56110010949	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
56110010950	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110010951	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110010952	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110010953	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
56110010954	putative ADP-binding pocket [chemical binding]; other site
56110010955	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
56110010956	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
56110010957	Mg++ binding site [ion binding]; other site
56110010958	putative catalytic motif [active]
56110010959	substrate binding site [chemical binding]; other site
56110010960	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
56110010961	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
56110010962	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
56110010963	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
56110010964	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
56110010965	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110010966	putative NAD(P) binding site [chemical binding]; other site
56110010967	active site
56110010968	putative substrate binding site [chemical binding]; other site
56110010969	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
56110010970	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
56110010971	C-terminal domain interface [polypeptide binding]; other site
56110010972	GSH binding site (G-site) [chemical binding]; other site
56110010973	dimer interface [polypeptide binding]; other site
56110010974	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
56110010975	N-terminal domain interface [polypeptide binding]; other site
56110010976	putative dimer interface [polypeptide binding]; other site
56110010977	active site
56110010978	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
56110010979	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110010980	putative active site [active]
56110010981	putative metal binding site [ion binding]; other site
56110010982	Serpin (serine protease inhibitor); Region: Serpin; pfam00079
56110010983	reactive center loop; other site
56110010984	SERine Proteinase INhibitors (serpins), prokaryotic subgroup. Little information about specific functions is available for this subgroup, most likely they are inhibitory members of the serpin superfamily. In general, serpins exhibit conformational...; Region: bacterial_SERPIN; cd02049
56110010985	reactive center loop; other site
56110010986	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110010987	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110010988	active site
56110010989	phosphorylation site [posttranslational modification]
56110010990	intermolecular recognition site; other site
56110010991	dimerization interface [polypeptide binding]; other site
56110010992	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110010993	DNA binding site [nucleotide binding]
56110010994	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
56110010995	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
56110010996	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110010997	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
56110010998	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
56110010999	Walker A/P-loop; other site
56110011000	ATP binding site [chemical binding]; other site
56110011001	Q-loop/lid; other site
56110011002	ABC transporter signature motif; other site
56110011003	Walker B; other site
56110011004	D-loop; other site
56110011005	H-loop/switch region; other site
56110011006	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011007	binding surface
56110011008	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110011009	TPR motif; other site
56110011010	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011011	binding surface
56110011012	TPR motif; other site
56110011013	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011014	binding surface
56110011015	TPR motif; other site
56110011016	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011017	binding surface
56110011018	TPR motif; other site
56110011019	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110011020	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011021	binding surface
56110011022	TPR motif; other site
56110011023	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011024	binding surface
56110011025	TPR motif; other site
56110011026	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011027	binding surface
56110011028	TPR motif; other site
56110011029	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
56110011030	Aspartase; Region: Aspartase; cd01357
56110011031	active sites [active]
56110011032	tetramer interface [polypeptide binding]; other site
56110011033	Uncharacterized conserved protein [Function unknown]; Region: COG2006
56110011034	Domain of unknown function (DUF362); Region: DUF362; pfam04015
56110011035	CHAT domain; Region: CHAT; pfam12770
56110011036	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
56110011037	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
56110011038	catalytic motif [active]
56110011039	Zn binding site [ion binding]; other site
56110011040	RibD C-terminal domain; Region: RibD_C; cl17279
56110011041	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
56110011042	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110011043	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
56110011044	catalytic triad [active]
56110011045	dimer interface [polypeptide binding]; other site
56110011046	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
56110011047	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
56110011048	D1 subunit  of photosystem II (PS II); Region: Photosystem-II_D1; cd09289
56110011049	protein I interface; other site
56110011050	D2 interface; other site
56110011051	protein T interface; other site
56110011052	chlorophyll binding site; other site
56110011053	beta carotene binding site; other site
56110011054	pheophytin binding site; other site
56110011055	manganese-stabilizing polypeptide interface; other site
56110011056	CP43 interface; other site
56110011057	protein L interface; other site
56110011058	oxygen evolving complex binding site; other site
56110011059	bromide binding site; other site
56110011060	quinone binding site; other site
56110011061	Fe binding site [ion binding]; other site
56110011062	core light harvesting interface; other site
56110011063	cytochrome b559 alpha subunit interface; other site
56110011064	cytochrome c-550 interface; other site
56110011065	protein J interface; other site
56110011066	GAF domain; Region: GAF_3; pfam13492
56110011067	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110011068	PAS domain; Region: PAS_9; pfam13426
56110011069	putative active site [active]
56110011070	heme pocket [chemical binding]; other site
56110011071	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110011072	PAS fold; Region: PAS_3; pfam08447
56110011073	putative active site [active]
56110011074	heme pocket [chemical binding]; other site
56110011075	PAS fold; Region: PAS_4; pfam08448
56110011076	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110011077	dimer interface [polypeptide binding]; other site
56110011078	phosphorylation site [posttranslational modification]
56110011079	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110011080	ATP binding site [chemical binding]; other site
56110011081	Mg2+ binding site [ion binding]; other site
56110011082	G-X-G motif; other site
56110011083	Response regulator receiver domain; Region: Response_reg; pfam00072
56110011084	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110011085	active site
56110011086	phosphorylation site [posttranslational modification]
56110011087	intermolecular recognition site; other site
56110011088	dimerization interface [polypeptide binding]; other site
56110011089	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110011090	putative binding surface; other site
56110011091	active site
56110011092	Response regulator receiver domain; Region: Response_reg; pfam00072
56110011093	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110011094	active site
56110011095	phosphorylation site [posttranslational modification]
56110011096	intermolecular recognition site; other site
56110011097	dimerization interface [polypeptide binding]; other site
56110011098	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110011099	dimer interface [polypeptide binding]; other site
56110011100	phosphorylation site [posttranslational modification]
56110011101	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110011102	ATP binding site [chemical binding]; other site
56110011103	Mg2+ binding site [ion binding]; other site
56110011104	G-X-G motif; other site
56110011105	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
56110011106	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
56110011107	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110011108	catalytic residue [active]
56110011109	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110011110	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
56110011111	CHAT domain; Region: CHAT; cl17868
56110011112	SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell...; Region: S2P-M50_SpoIVFB_CBS; cd06164
56110011113	Peptidase family M50; Region: Peptidase_M50; pfam02163
56110011114	active site
56110011115	putative substrate binding region [chemical binding]; other site
56110011116	FOG: CBS domain [General function prediction only]; Region: COG0517
56110011117	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the metalloprotease peptidase M50.  CBS is a small domain originally identified in cystathionine beta-synthase and subsequently found in a wide...; Region: CBS_pair_M50_like; cd04801
56110011118	Mo-dependent nitrogenase C-terminus; Region: Mo-nitro_C; pfam06967
56110011119	Uncharacterized conserved protein [Function unknown]; Region: COG4715
56110011120	tetratricopeptide repeat protein; Provisional; Region: PRK11788
56110011121	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110011122	Uncharacterized conserved protein [Function unknown]; Region: COG4715
56110011123	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110011124	putative active site [active]
56110011125	AAA ATPase domain; Region: AAA_16; pfam13191
56110011126	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011127	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011128	binding surface
56110011129	TPR motif; other site
56110011130	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011131	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011132	TPR motif; other site
56110011133	binding surface
56110011134	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011135	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011136	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011137	binding surface
56110011138	TPR motif; other site
56110011139	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011140	AAA domain; Region: AAA_33; pfam13671
56110011141	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
56110011142	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
56110011143	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
56110011144	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
56110011145	Protein kinase domain; Region: Pkinase; pfam00069
56110011146	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110011147	active site
56110011148	ATP binding site [chemical binding]; other site
56110011149	substrate binding site [chemical binding]; other site
56110011150	activation loop (A-loop); other site
56110011151	GUN4-like; Region: GUN4; pfam05419
56110011152	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
56110011153	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
56110011154	glutaminase active site [active]
56110011155	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
56110011156	dimer interface [polypeptide binding]; other site
56110011157	active site
56110011158	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
56110011159	dimer interface [polypeptide binding]; other site
56110011160	active site
56110011161	photosystem I subunit VII; Region: psaC; CHL00065
56110011162	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
56110011163	Heterodisulfide reductase, subunit B [Energy production and conversion]; Region: HdrB; COG2048
56110011164	Cysteine-rich domain; Region: CCG; pfam02754
56110011165	Cysteine-rich domain; Region: CCG; pfam02754
56110011166	acyl carrier protein; Provisional; Region: acpP; PRK00982
56110011167	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
56110011168	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
56110011169	dimer interface [polypeptide binding]; other site
56110011170	active site
56110011171	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
56110011172	transketolase; Region: PLN02790
56110011173	TPP-binding site [chemical binding]; other site
56110011174	dimer interface [polypeptide binding]; other site
56110011175	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
56110011176	PYR/PP interface [polypeptide binding]; other site
56110011177	dimer interface [polypeptide binding]; other site
56110011178	TPP binding site [chemical binding]; other site
56110011179	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
56110011180	sucrose synthase; Region: sucr_synth; TIGR02470
56110011181	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
56110011182	putative ADP-binding pocket [chemical binding]; other site
56110011183	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110011184	Calx-beta domain; Region: Calx-beta; cl02522
56110011185	Calx-beta domain; Region: Calx-beta; cl02522
56110011186	Calx-beta domain; Region: Calx-beta; cl02522
56110011187	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
56110011188	active site
56110011189	catalytic residues [active]
56110011190	metal binding site [ion binding]; metal-binding site
56110011191	carotene isomerase; Region: carot_isom; TIGR02730
56110011192	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110011193	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110011194	active site
56110011195	YGGT family; Region: YGGT; pfam02325
56110011196	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
56110011197	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
56110011198	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
56110011199	shikimate binding site; other site
56110011200	NAD(P) binding site [chemical binding]; other site
56110011201	Sensors of blue-light using FAD; Region: BLUF; pfam04940
56110011202	cyclase homology domain; Region: CHD; cd07302
56110011203	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110011204	nucleotidyl binding site; other site
56110011205	metal binding site [ion binding]; metal-binding site
56110011206	dimer interface [polypeptide binding]; other site
56110011207	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
56110011208	active site
56110011209	catalytic triad [active]
56110011210	oxyanion hole [active]
56110011211	Alkaline and neutral invertase; Region: Glyco_hydro_100; pfam12899
56110011212	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
56110011213	adaptive-response sensory kinase; Validated; Region: PRK09303
56110011214	KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part...; Region: KaiB_like; cd02978
56110011215	tetramer interface [polypeptide binding]; other site
56110011216	dimer interface [polypeptide binding]; other site
56110011217	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110011218	ATP binding site [chemical binding]; other site
56110011219	Mg2+ binding site [ion binding]; other site
56110011220	G-X-G motif; other site
56110011221	Predicted membrane protein (DUF2079); Region: DUF2079; pfam09852
56110011222	Predicted membrane protein [Function unknown]; Region: COG3463
56110011223	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110011224	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110011225	Cache domain; Region: Cache_1; pfam02743
56110011226	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110011227	dimerization interface [polypeptide binding]; other site
56110011228	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110011229	cyclase homology domain; Region: CHD; cd07302
56110011230	nucleotidyl binding site; other site
56110011231	metal binding site [ion binding]; metal-binding site
56110011232	dimer interface [polypeptide binding]; other site
56110011233	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
56110011234	Predicted ATPase [General function prediction only]; Region: COG4637
56110011235	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110011236	Walker A/P-loop; other site
56110011237	ATP binding site [chemical binding]; other site
56110011238	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
56110011239	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
56110011240	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110011241	ATP binding site [chemical binding]; other site
56110011242	putative Mg++ binding site [ion binding]; other site
56110011243	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110011244	nucleotide binding region [chemical binding]; other site
56110011245	ATP-binding site [chemical binding]; other site
56110011246	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
56110011247	HRDC domain; Region: HRDC; pfam00570
56110011248	HRDC domain; Region: HRDC; pfam00570
56110011249	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2343
56110011250	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110011251	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110011252	active site
56110011253	ATP binding site [chemical binding]; other site
56110011254	substrate binding site [chemical binding]; other site
56110011255	activation loop (A-loop); other site
56110011256	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011257	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110011258	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011259	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011260	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
56110011261	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
56110011262	putative tRNA-binding site [nucleotide binding]; other site
56110011263	B3/4 domain; Region: B3_4; pfam03483
56110011264	tRNA synthetase B5 domain; Region: B5; smart00874
56110011265	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
56110011266	dimer interface [polypeptide binding]; other site
56110011267	motif 1; other site
56110011268	motif 3; other site
56110011269	motif 2; other site
56110011270	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
56110011271	YCII-related domain; Region: YCII; cl00999
56110011272	Double zinc ribbon; Region: DZR; pfam12773
56110011273	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
56110011274	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
56110011275	Protein phosphatase 2C; Region: PP2C; pfam00481
56110011276	active site
56110011277	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110011278	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110011279	phosphopeptide binding site; other site
56110011280	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110011281	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110011282	active site
56110011283	ATP binding site [chemical binding]; other site
56110011284	substrate binding site [chemical binding]; other site
56110011285	activation loop (A-loop); other site
56110011286	Domain of unknown function (DUF4327); Region: DUF4327; pfam14217
56110011287	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
56110011288	DNA binding residues [nucleotide binding]
56110011289	AAA ATPase domain; Region: AAA_16; pfam13191
56110011290	NACHT domain; Region: NACHT; pfam05729
56110011291	Protein of unknown function (DUF3419); Region: DUF3419; cl15422
56110011292	putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional; Region: PRK12344
56110011293	Desulfobacterium autotrophicum LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA3; cd07941
56110011294	active site
56110011295	catalytic residues [active]
56110011296	metal binding site [ion binding]; metal-binding site
56110011297	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
56110011298	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
56110011299	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110011300	catalytic loop [active]
56110011301	iron binding site [ion binding]; other site
56110011302	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
56110011303	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
56110011304	ThiS interaction site; other site
56110011305	putative active site [active]
56110011306	tetramer interface [polypeptide binding]; other site
56110011307	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011308	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011309	binding surface
56110011310	TPR motif; other site
56110011311	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011312	DEAD-like helicases superfamily; Region: DEXDc; smart00487
56110011313	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110011314	ATP binding site [chemical binding]; other site
56110011315	putative Mg++ binding site [ion binding]; other site
56110011316	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110011317	nucleotide binding region [chemical binding]; other site
56110011318	ATP-binding site [chemical binding]; other site
56110011319	DSHCT (NUC185) domain; Region: DSHCT; pfam08148
56110011320	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4634
56110011321	Uncharacterized conserved protein [Function unknown]; Region: COG2442
56110011322	TPR repeat; Region: TPR_11; pfam13414
56110011323	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011324	binding surface
56110011325	TPR motif; other site
56110011326	TPR repeat; Region: TPR_11; pfam13414
56110011327	TPR repeat; Region: TPR_11; pfam13414
56110011328	DEAD-like helicases superfamily; Region: DEXDc; smart00487
56110011329	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110011330	ATP binding site [chemical binding]; other site
56110011331	putative Mg++ binding site [ion binding]; other site
56110011332	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110011333	putative active site [active]
56110011334	T5orf172 domain; Region: T5orf172; pfam10544
56110011335	Predicted ATPase [General function prediction only]; Region: COG4637
56110011336	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110011337	Walker A/P-loop; other site
56110011338	ATP binding site [chemical binding]; other site
56110011339	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
56110011340	ABC transporter signature motif; other site
56110011341	Walker B; other site
56110011342	D-loop; other site
56110011343	H-loop/switch region; other site
56110011344	XisI protein; Region: XisI; pfam08869
56110011345	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
56110011346	Methyltransferase domain; Region: Methyltransf_26; pfam13659
56110011347	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
56110011348	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
56110011349	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
56110011350	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
56110011351	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
56110011352	Putative amidoligase enzyme (DUF2126); Region: DUF2126; pfam09899
56110011353	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4196
56110011354	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
56110011355	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
56110011356	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110011357	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110011358	CHAT domain; Region: CHAT; pfam12770
56110011359	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110011360	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110011361	CHAT domain; Region: CHAT; cl17868
56110011362	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110011363	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110011364	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110011365	active site
56110011366	phosphorylation site [posttranslational modification]
56110011367	intermolecular recognition site; other site
56110011368	dimerization interface [polypeptide binding]; other site
56110011369	magnesium chelatase subunit H; Provisional; Region: PLN03241
56110011370	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
56110011371	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110011372	putative active site [active]
56110011373	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
56110011374	Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136
56110011375	NAD(P) binding site [chemical binding]; other site
56110011376	catalytic residues [active]
56110011377	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
56110011378	bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and...; Region: arch_bact_SO_family_Moco; cd02109
56110011379	Moco binding site; other site
56110011380	metal coordination site [ion binding]; other site
56110011381	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
56110011382	TrkA-N domain; Region: TrkA_N; pfam02254
56110011383	TrkA-C domain; Region: TrkA_C; pfam02080
56110011384	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
56110011385	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
56110011386	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
56110011387	NMT1-like family; Region: NMT1_2; pfam13379
56110011388	CHASE3 domain; Region: CHASE3; pfam05227
56110011389	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110011390	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110011391	dimer interface [polypeptide binding]; other site
56110011392	putative CheW interface [polypeptide binding]; other site
56110011393	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110011394	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110011395	S-adenosylmethionine binding site [chemical binding]; other site
56110011396	tocopherol phytyltransferase; Reviewed; Region: ubiA; PRK12887
56110011397	UbiA prenyltransferase family; Region: UbiA; pfam01040
56110011398	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011399	binding surface
56110011400	TPR motif; other site
56110011401	TPR repeat; Region: TPR_11; pfam13414
56110011402	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011403	binding surface
56110011404	TPR motif; other site
56110011405	TPR repeat; Region: TPR_11; pfam13414
56110011406	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
56110011407	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110011408	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011409	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011410	TPR motif; other site
56110011411	TPR repeat; Region: TPR_11; pfam13414
56110011412	binding surface
56110011413	TPR repeat; Region: TPR_11; pfam13414
56110011414	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011415	binding surface
56110011416	TPR motif; other site
56110011417	TPR repeat; Region: TPR_11; pfam13414
56110011418	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110011419	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110011420	TPR repeat; Region: TPR_11; pfam13414
56110011421	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011422	binding surface
56110011423	TPR motif; other site
56110011424	TPR repeat; Region: TPR_11; pfam13414
56110011425	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011426	binding surface
56110011427	TPR repeat; Region: TPR_11; pfam13414
56110011428	TPR motif; other site
56110011429	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011430	binding surface
56110011431	TPR repeat; Region: TPR_11; pfam13414
56110011432	TPR motif; other site
56110011433	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
56110011434	TPR repeat; Region: TPR_11; pfam13414
56110011435	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011436	binding surface
56110011437	TPR motif; other site
56110011438	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110011439	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110011440	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110011441	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
56110011442	HEPN domain; Region: HEPN; cl00824
56110011443	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110011444	active site
56110011445	NTP binding site [chemical binding]; other site
56110011446	metal binding triad [ion binding]; metal-binding site
56110011447	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110011448	active site
56110011449	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
56110011450	active site
56110011451	SAM binding site [chemical binding]; other site
56110011452	homodimer interface [polypeptide binding]; other site
56110011453	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
56110011454	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
56110011455	active site
56110011456	S-layer homology domain; Region: SLH; pfam00395
56110011457	S-layer homology domain; Region: SLH; pfam00395
56110011458	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
56110011459	Sulfatase; Region: Sulfatase; cl17466
56110011460	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
56110011461	dephospho-CoA kinase; Region: TIGR00152
56110011462	CoA-binding site [chemical binding]; other site
56110011463	ATP-binding [chemical binding]; other site
56110011464	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
56110011465	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110011466	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
56110011467	Sensory domain found in DIguanylate Cyclases & Two-component systems; Region: DICT; cl01731
56110011468	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110011469	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110011470	dimer interface [polypeptide binding]; other site
56110011471	phosphorylation site [posttranslational modification]
56110011472	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110011473	ATP binding site [chemical binding]; other site
56110011474	Mg2+ binding site [ion binding]; other site
56110011475	G-X-G motif; other site
56110011476	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
56110011477	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
56110011478	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
56110011479	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
56110011480	Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768
56110011481	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
56110011482	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
56110011483	Active Sites [active]
56110011484	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
56110011485	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
56110011486	active site
56110011487	metal binding site [ion binding]; metal-binding site
56110011488	DNA binding site [nucleotide binding]
56110011489	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
56110011490	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
56110011491	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
56110011492	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
56110011493	active site
56110011494	catalytic tetrad [active]
56110011495	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110011496	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110011497	active site
56110011498	ATP binding site [chemical binding]; other site
56110011499	substrate binding site [chemical binding]; other site
56110011500	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110011501	active site
56110011502	ATP binding site [chemical binding]; other site
56110011503	substrate binding site [chemical binding]; other site
56110011504	activation loop (A-loop); other site
56110011505	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
56110011506	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
56110011507	ligand binding site [chemical binding]; other site
56110011508	flagellar motor protein MotS; Reviewed; Region: PRK06742
56110011509	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
56110011510	ligand binding site [chemical binding]; other site
56110011511	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
56110011512	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
56110011513	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110011514	CHAT domain; Region: CHAT; cl17868
56110011515	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110011516	CHASE2 domain; Region: CHASE2; pfam05226
56110011517	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110011518	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011519	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011520	binding surface
56110011521	TPR motif; other site
56110011522	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011523	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011524	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011525	binding surface
56110011526	TPR motif; other site
56110011527	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011528	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011529	binding surface
56110011530	TPR motif; other site
56110011531	TPR repeat; Region: TPR_11; pfam13414
56110011532	CHAT domain; Region: CHAT; pfam12770
56110011533	RNA binding activity-knot of a chromodomain; Region: Tudor-knot; pfam11717
56110011534	RNA binding activity-knot of a chromodomain; Region: Tudor-knot; pfam11717
56110011535	threonine dehydratase; Reviewed; Region: PRK09224
56110011536	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
56110011537	tetramer interface [polypeptide binding]; other site
56110011538	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110011539	catalytic residue [active]
56110011540	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
56110011541	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
56110011542	putative Ile/Val binding site [chemical binding]; other site
56110011543	TIGR03032 family protein; Region: TIGR03032
56110011544	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110011545	Family description; Region: VCBS; pfam13517
56110011546	Family description; Region: VCBS; pfam13517
56110011547	Family description; Region: VCBS; pfam13517
56110011548	Family description; Region: VCBS; pfam13517
56110011549	Family description; Region: VCBS; pfam13517
56110011550	FG-GAP repeat; Region: FG-GAP; pfam01839
56110011551	Family description; Region: VCBS; pfam13517
56110011552	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
56110011553	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
56110011554	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
56110011555	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
56110011556	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
56110011557	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
56110011558	Cadherin repeat-like domain; Region: CA_like; cl15786
56110011559	Ca2+ binding site [ion binding]; other site
56110011560	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110011561	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110011562	putative active site [active]
56110011563	S-layer homology domain; Region: SLH; pfam00395
56110011564	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
56110011565	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110011566	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110011567	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110011568	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
56110011569	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
56110011570	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110011571	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110011572	DNA binding residues [nucleotide binding]
56110011573	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
56110011574	MoaE homodimer interface [polypeptide binding]; other site
56110011575	MoaD interaction [polypeptide binding]; other site
56110011576	active site residues [active]
56110011577	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
56110011578	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
56110011579	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
56110011580	Sporulation and spore germination; Region: Germane; pfam10646
56110011581	SnoaL-like domain; Region: SnoaL_2; pfam12680
56110011582	TniQ; Region: TniQ; pfam06527
56110011583	Helix-turn-helix domain; Region: HTH_28; pfam13518
56110011584	Winged helix-turn helix; Region: HTH_29; pfam13551
56110011585	Homeodomain-like domain; Region: HTH_32; pfam13565
56110011586	Integrase core domain; Region: rve; pfam00665
56110011587	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
56110011588	Domain of unknown function (DUF1993); Region: DUF1993; cl01567
56110011589	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
56110011590	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110011591	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011592	WD40 repeats; Region: WD40; smart00320
56110011593	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110011594	structural tetrad; other site
56110011595	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110011596	structural tetrad; other site
56110011597	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110011598	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110011599	active site
56110011600	ATP binding site [chemical binding]; other site
56110011601	substrate binding site [chemical binding]; other site
56110011602	activation loop (A-loop); other site
56110011603	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110011604	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110011605	structural tetrad; other site
56110011606	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110011607	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110011608	dimer interface [polypeptide binding]; other site
56110011609	phosphorylation site [posttranslational modification]
56110011610	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110011611	ATP binding site [chemical binding]; other site
56110011612	Mg2+ binding site [ion binding]; other site
56110011613	G-X-G motif; other site
56110011614	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110011615	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110011616	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110011617	metal binding site [ion binding]; metal-binding site
56110011618	active site
56110011619	I-site; other site
56110011620	Predicted permease; Region: DUF318; cl17795
56110011621	Predicted permease; Region: DUF318; cl17795
56110011622	TIGR03943 family protein; Region: TIGR03943
56110011623	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011624	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110011625	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011626	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011627	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011628	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110011629	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011630	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011631	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110011632	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011633	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011634	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011635	Protein of unknown function (DUF3082); Region: DUF3082; pfam11282
56110011636	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK02534
56110011637	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
56110011638	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
56110011639	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
56110011640	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110011641	S-adenosylmethionine binding site [chemical binding]; other site
56110011642	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
56110011643	active site residue [active]
56110011644	Glycogen debranching enzyme N terminal; Region: GDE_N; pfam12439
56110011645	glycogen debranching enzyme, archaeal type, putative; Region: gde_arch; TIGR01561
56110011646	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
56110011647	Domain of unknown function (DUF4281); Region: DUF4281; pfam14108
56110011648	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
56110011649	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
56110011650	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
56110011651	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
56110011652	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
56110011653	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
56110011654	TPR repeat; Region: TPR_11; pfam13414
56110011655	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011656	binding surface
56110011657	TPR motif; other site
56110011658	TPR repeat; Region: TPR_11; pfam13414
56110011659	TPR repeat; Region: TPR_11; pfam13414
56110011660	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011661	binding surface
56110011662	TPR motif; other site
56110011663	TPR repeat; Region: TPR_11; pfam13414
56110011664	TPR repeat; Region: TPR_11; pfam13414
56110011665	Protein of unknown function (DUF563); Region: DUF563; pfam04577
56110011666	septum formation inhibitor; Reviewed; Region: minC; PRK00513
56110011667	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
56110011668	septum-site determining protein; Validated; Region: minD; CHL00175
56110011669	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
56110011670	Switch I; other site
56110011671	Switch II; other site
56110011672	cell division topological specificity factor MinE; Provisional; Region: PRK13988
56110011673	ATP synthase CF1 beta subunit; Region: atpB; CHL00060
56110011674	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
56110011675	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
56110011676	alpha subunit interaction interface [polypeptide binding]; other site
56110011677	Walker A motif; other site
56110011678	ATP binding site [chemical binding]; other site
56110011679	Walker B motif; other site
56110011680	inhibitor binding site; inhibition site
56110011681	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
56110011682	ATP synthase CF1 epsilon subunit; Region: atpE; CHL00063
56110011683	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
56110011684	gamma subunit interface [polypeptide binding]; other site
56110011685	epsilon subunit interface [polypeptide binding]; other site
56110011686	LBP interface [polypeptide binding]; other site
56110011687	Protein of unknown function (DUF3177); Region: DUF3177; pfam11375
56110011688	CP12 domain; Region: CP12; pfam02672
56110011689	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4398
56110011690	FIST N domain; Region: FIST; pfam08495
56110011691	FIST C domain; Region: FIST_C; pfam10442
56110011692	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
56110011693	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
56110011694	active site
56110011695	metal binding site [ion binding]; metal-binding site
56110011696	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
56110011697	TRAP-type mannitol/chloroaromatic compound transport system, small permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FcbT2; COG4665
56110011698	TRAP-type mannitol/chloroaromatic compound transport system, large permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FcbT3; COG4664
56110011699	DctM-like transporters; Region: DctM; pfam06808
56110011700	Domain of unknown function (DUF4278); Region: DUF4278; pfam14105
56110011701	NDF6 (NDH-dependent flow 6); Provisional; Region: PLN00180
56110011702	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
56110011703	active site
56110011704	DNA binding site [nucleotide binding]
56110011705	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
56110011706	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
56110011707	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
56110011708	Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_9; cd06344
56110011709	putative ligand binding site [chemical binding]; other site
56110011710	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
56110011711	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110011712	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
56110011713	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
56110011714	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011715	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011716	binding surface
56110011717	TPR motif; other site
56110011718	TPR repeat; Region: TPR_11; pfam13414
56110011719	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011720	binding surface
56110011721	TPR motif; other site
56110011722	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011723	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011724	Tetratricopeptide repeat; Region: TPR_10; pfam13374
56110011725	CHAT domain; Region: CHAT; pfam12770
56110011726	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110011727	putative active site [active]
56110011728	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
56110011729	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
56110011730	Putative restriction endonuclease; Region: Uma2; pfam05685
56110011731	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
56110011732	metal ion-dependent adhesion site (MIDAS); other site
56110011733	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
56110011734	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
56110011735	active site
56110011736	ATP binding site [chemical binding]; other site
56110011737	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110011738	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110011739	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
56110011740	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
56110011741	active site
56110011742	homodimer interface [polypeptide binding]; other site
56110011743	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
56110011744	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110011745	Walker A motif; other site
56110011746	ATP binding site [chemical binding]; other site
56110011747	Walker B motif; other site
56110011748	KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part...; Region: KaiB_like; cd02978
56110011749	tetramer interface [polypeptide binding]; other site
56110011750	dimer interface [polypeptide binding]; other site
56110011751	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
56110011752	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
56110011753	Nucleoside recognition; Region: Gate; pfam07670
56110011754	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
56110011755	TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA...; Region: TlpA_like_DipZ_like; cd03012
56110011756	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110011757	catalytic residues [active]
56110011758	Bacterial SH3 domain; Region: SH3_3; cl17532
56110011759	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
56110011760	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
56110011761	active site
56110011762	metal binding site [ion binding]; metal-binding site
56110011763	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
56110011764	CTP synthetase; Validated; Region: pyrG; PRK05380
56110011765	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
56110011766	Catalytic site [active]
56110011767	active site
56110011768	UTP binding site [chemical binding]; other site
56110011769	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
56110011770	active site
56110011771	putative oxyanion hole; other site
56110011772	catalytic triad [active]
56110011773	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
56110011774	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
56110011775	nucleotide binding site [chemical binding]; other site
56110011776	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
56110011777	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110011778	dimer interface [polypeptide binding]; other site
56110011779	conserved gate region; other site
56110011780	ABC-ATPase subunit interface; other site
56110011781	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110011782	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
56110011783	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110011784	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
56110011785	NAD(P) binding site [chemical binding]; other site
56110011786	active site
56110011787	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110011788	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110011789	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110011790	GAF domain; Region: GAF; pfam01590
56110011791	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110011792	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110011793	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110011794	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110011795	dimer interface [polypeptide binding]; other site
56110011796	phosphorylation site [posttranslational modification]
56110011797	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110011798	ATP binding site [chemical binding]; other site
56110011799	Mg2+ binding site [ion binding]; other site
56110011800	G-X-G motif; other site
56110011801	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
56110011802	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110011803	Walker A/P-loop; other site
56110011804	ATP binding site [chemical binding]; other site
56110011805	Q-loop/lid; other site
56110011806	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110011807	ABC transporter signature motif; other site
56110011808	Walker B; other site
56110011809	D-loop; other site
56110011810	H-loop/switch region; other site
56110011811	GAF domain; Region: GAF_2; pfam13185
56110011812	GAF domain; Region: GAF; pfam01590
56110011813	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110011814	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110011815	dimer interface [polypeptide binding]; other site
56110011816	phosphorylation site [posttranslational modification]
56110011817	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110011818	ATP binding site [chemical binding]; other site
56110011819	Mg2+ binding site [ion binding]; other site
56110011820	G-X-G motif; other site
56110011821	Protein of unknown function (DUF3155); Region: DUF3155; pfam11352
56110011822	Protein of unknown function (DUF3529); Region: DUF3529; pfam12046
56110011823	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
56110011824	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
56110011825	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
56110011826	active site
56110011827	catalytic site [active]
56110011828	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
56110011829	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110011830	putative catalytic residue [active]
56110011831	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110011832	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011833	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011834	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011835	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011836	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011837	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110011838	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110011839	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
56110011840	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
56110011841	DNA binding residues [nucleotide binding]
56110011842	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
56110011843	catalytic residues [active]
56110011844	catalytic nucleophile [active]
56110011845	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110011846	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110011847	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
56110011848	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
56110011849	putative active site [active]
56110011850	catalytic triad [active]
56110011851	putative dimer interface [polypeptide binding]; other site
56110011852	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
56110011853	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
56110011854	CAP-like domain; other site
56110011855	active site
56110011856	primary dimer interface [polypeptide binding]; other site
56110011857	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110011858	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110011859	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110011860	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110011861	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110011862	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110011863	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
56110011864	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII; cd09992
56110011865	active site
56110011866	Zn binding site [ion binding]; other site
56110011867	Uncharacterized conserved protein [Function unknown]; Region: COG1479
56110011868	Protein of unknown function DUF262; Region: DUF262; pfam03235
56110011869	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
56110011870	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
56110011871	The C-terminal domain of a subfamily of Na+ /H+ antiporter existed in bacteria and archea . Na+/H+ exchange proteins eject protons from cells, effectively eliminating excess acid from actively metabolising cells. Na+ /H+ exchange activity is also crucial...; Region: Na_H_Antiporter_C; cd01988
56110011872	Ligand Binding Site [chemical binding]; other site
56110011873	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110011874	Ligand Binding Site [chemical binding]; other site
56110011875	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
56110011876	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
56110011877	Zn2+ binding site [ion binding]; other site
56110011878	Mg2+ binding site [ion binding]; other site
56110011879	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110011880	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110011881	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
56110011882	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
56110011883	Surface antigen; Region: Bac_surface_Ag; pfam01103
56110011884	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011885	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011886	binding surface
56110011887	TPR motif; other site
56110011888	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011889	CHAT domain; Region: CHAT; cl17868
56110011890	Myosin head (motor domain); Region: Myosin_head; pfam00063
56110011891	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110011892	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110011893	active site
56110011894	ATP binding site [chemical binding]; other site
56110011895	substrate binding site [chemical binding]; other site
56110011896	activation loop (A-loop); other site
56110011897	TPR repeat; Region: TPR_11; pfam13414
56110011898	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011899	binding surface
56110011900	TPR motif; other site
56110011901	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011902	binding surface
56110011903	TPR repeat; Region: TPR_11; pfam13414
56110011904	TPR motif; other site
56110011905	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110011906	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110011907	active site
56110011908	ATP binding site [chemical binding]; other site
56110011909	substrate binding site [chemical binding]; other site
56110011910	activation loop (A-loop); other site
56110011911	AAA ATPase domain; Region: AAA_16; pfam13191
56110011912	NACHT domain; Region: NACHT; pfam05729
56110011913	Homeodomain-like domain; Region: HTH_23; pfam13384
56110011914	Winged helix-turn helix; Region: HTH_29; pfam13551
56110011915	Winged helix-turn helix; Region: HTH_33; pfam13592
56110011916	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110011917	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110011918	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
56110011919	active site
56110011920	4Fe-4S binding domain; Region: Fer4_5; pfam12801
56110011921	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110011922	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110011923	phosphopeptide binding site; other site
56110011924	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
56110011925	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
56110011926	FAD binding pocket [chemical binding]; other site
56110011927	FAD binding motif [chemical binding]; other site
56110011928	phosphate binding motif [ion binding]; other site
56110011929	beta-alpha-beta structure motif; other site
56110011930	NAD binding pocket [chemical binding]; other site
56110011931	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110011932	catalytic loop [active]
56110011933	iron binding site [ion binding]; other site
56110011934	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011935	Tetratricopeptide repeat; Region: TPR_10; cl17452
56110011936	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011937	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110011938	binding surface
56110011939	TPR motif; other site
56110011940	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110011941	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
56110011942	putative active site [active]
56110011943	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110011944	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110011945	active site
56110011946	ATP binding site [chemical binding]; other site
56110011947	substrate binding site [chemical binding]; other site
56110011948	activation loop (A-loop); other site
56110011949	Uncharacterized conserved protein [Function unknown]; Region: COG1262
56110011950	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
56110011951	Protein kinase domain; Region: Pkinase; pfam00069
56110011952	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110011953	active site
56110011954	ATP binding site [chemical binding]; other site
56110011955	substrate binding site [chemical binding]; other site
56110011956	activation loop (A-loop); other site
56110011957	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110011958	putative active site [active]
56110011959	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cl01898
56110011960	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110011961	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110011962	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
56110011963	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110011964	S-adenosylmethionine binding site [chemical binding]; other site
56110011965	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
56110011966	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
56110011967	dimer interface [polypeptide binding]; other site
56110011968	ssDNA binding site [nucleotide binding]; other site
56110011969	tetramer (dimer of dimers) interface [polypeptide binding]; other site
56110011970	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
56110011971	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
56110011972	active site
56110011973	Substrate binding site; other site
56110011974	Mg++ binding site; other site
56110011975	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
56110011976	putative CoA binding site [chemical binding]; other site
56110011977	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
56110011978	GTP-mannose-1-phosphate guanyltransferase (MPG1 transferase), also known as GDP-mannose pyrophosphorylase, is a bifunctional enzyme with both phosphomannose isomerase (PMI) activity and GDP-mannose phosphorylase (GMP) activity.  The protein contains an...; Region: MPG1_transferase; cd05805
56110011979	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110011980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110011981	S-adenosylmethionine binding site [chemical binding]; other site
56110011982	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
56110011983	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
56110011984	Walker A/P-loop; other site
56110011985	ATP binding site [chemical binding]; other site
56110011986	Q-loop/lid; other site
56110011987	ABC transporter signature motif; other site
56110011988	Walker B; other site
56110011989	D-loop; other site
56110011990	H-loop/switch region; other site
56110011991	TOBE domain; Region: TOBE_2; pfam08402
56110011992	putative high light inducible protein; Region: PHA02337
56110011993	RNA polymerase sigma factor RpoD; Validated; Region: PRK07406
56110011994	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
56110011995	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110011996	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
56110011997	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110011998	DNA binding residues [nucleotide binding]
56110011999	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
56110012000	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
56110012001	NodB motif; other site
56110012002	active site
56110012003	catalytic site [active]
56110012004	metal binding site [ion binding]; metal-binding site
56110012005	Protein kinase domain; Region: Pkinase; pfam00069
56110012006	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012007	active site
56110012008	substrate binding site [chemical binding]; other site
56110012009	ATP binding site [chemical binding]; other site
56110012010	activation loop (A-loop); other site
56110012011	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110012012	CHASE2 domain; Region: CHASE2; pfam05226
56110012013	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110012014	cyclase homology domain; Region: CHD; cd07302
56110012015	nucleotidyl binding site; other site
56110012016	metal binding site [ion binding]; metal-binding site
56110012017	dimer interface [polypeptide binding]; other site
56110012018	FecR protein; Region: FecR; pfam04773
56110012019	Helix-turn-helix domain; Region: HTH_25; pfam13413
56110012020	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110012021	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
56110012022	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
56110012023	threonine synthase; Reviewed; Region: PRK06721
56110012024	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
56110012025	homodimer interface [polypeptide binding]; other site
56110012026	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110012027	catalytic residue [active]
56110012028	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
56110012029	The Delta12 Fatty Acid Desaturase (Delta12-FADS)-like CD includes the integral-membrane enzymes, delta-12 acyl-lipid desaturases, oleate 12-hydroxylases, omega3 and omega6 fatty acid desaturases, and other related proteins, found in a wide range of...; Region: Delta12-FADS-like; cd03507
56110012030	putative di-iron ligands [ion binding]; other site
56110012031	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
56110012032	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
56110012033	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110012034	TRX domain, novel NADPH thioredoxin reductase (NTR) family; composed of fusion proteins found only in oxygenic photosynthetic organisms containing both TRX and NTR domains. The TRX domain functions as a protein disulfide reductase via the reversible...; Region: TRX_NTR; cd02949
56110012035	catalytic residues [active]
56110012036	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110012037	S-adenosylmethionine binding site [chemical binding]; other site
56110012038	ubiquinone biosynthesis methyltransferase; Region: PLN02232
56110012039	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
56110012040	putative ADP-ribose binding site [chemical binding]; other site
56110012041	putative active site [active]
56110012042	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
56110012043	dimer interface [polypeptide binding]; other site
56110012044	ADP-ribose binding site [chemical binding]; other site
56110012045	active site
56110012046	nudix motif; other site
56110012047	metal binding site [ion binding]; metal-binding site
56110012048	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2343
56110012049	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110012050	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012051	active site
56110012052	ATP binding site [chemical binding]; other site
56110012053	substrate binding site [chemical binding]; other site
56110012054	activation loop (A-loop); other site
56110012055	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110012056	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012057	active site
56110012058	ATP binding site [chemical binding]; other site
56110012059	substrate binding site [chemical binding]; other site
56110012060	activation loop (A-loop); other site
56110012061	GUN4-like; Region: GUN4; pfam05419
56110012062	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110012063	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012064	active site
56110012065	ATP binding site [chemical binding]; other site
56110012066	substrate binding site [chemical binding]; other site
56110012067	substrate binding site [chemical binding]; other site
56110012068	activation loop (A-loop); other site
56110012069	activation loop (A-loop); other site
56110012070	GUN4-like; Region: GUN4; pfam05419
56110012071	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
56110012072	DNA protecting protein DprA; Region: dprA; TIGR00732
56110012073	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
56110012074	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
56110012075	HIGH motif; other site
56110012076	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
56110012077	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
56110012078	active site
56110012079	KMSKS motif; other site
56110012080	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
56110012081	tRNA binding surface [nucleotide binding]; other site
56110012082	anticodon binding site; other site
56110012083	Domain of unknown function (DUF4308); Region: DUF4308; pfam14159
56110012084	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
56110012085	FOG: CBS domain [General function prediction only]; Region: COG0517
56110012086	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110012087	PAS domain; Region: PAS_9; pfam13426
56110012088	PAS domain S-box; Region: sensory_box; TIGR00229
56110012089	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012090	putative active site [active]
56110012091	heme pocket [chemical binding]; other site
56110012092	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012093	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012094	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110012095	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110012096	metal binding site [ion binding]; metal-binding site
56110012097	active site
56110012098	I-site; other site
56110012099	Tocopherol cyclase; Region: Tocopherol_cycl; pfam14249
56110012100	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110012101	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110012102	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110012103	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110012104	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110012105	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110012106	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110012107	putative active site [active]
56110012108	putative NTP binding site [chemical binding]; other site
56110012109	putative nucleic acid binding site [nucleotide binding]; other site
56110012110	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110012111	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110012112	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110012113	active site
56110012114	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
56110012115	This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible...; Region: PGM_like2; cd05800
56110012116	active site
56110012117	substrate binding site [chemical binding]; other site
56110012118	metal binding site [ion binding]; metal-binding site
56110012119	AMIN domain; Region: AMIN; pfam11741
56110012120	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
56110012121	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
56110012122	Sulfate transporter family; Region: Sulfate_transp; pfam00916
56110012123	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
56110012124	Protein of unknown function (DUF3172); Region: DUF3172; pfam11371
56110012125	Predicted permease [General function prediction only]; Region: COG3329
56110012126	Late competence development protein ComFB; Region: ComFB; pfam10719
56110012127	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110012128	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012129	active site
56110012130	ATP binding site [chemical binding]; other site
56110012131	substrate binding site [chemical binding]; other site
56110012132	activation loop (A-loop); other site
56110012133	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110012134	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110012135	structural tetrad; other site
56110012136	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012137	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012138	active site
56110012139	phosphorylation site [posttranslational modification]
56110012140	intermolecular recognition site; other site
56110012141	dimerization interface [polypeptide binding]; other site
56110012142	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012143	dimer interface [polypeptide binding]; other site
56110012144	phosphorylation site [posttranslational modification]
56110012145	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012146	ATP binding site [chemical binding]; other site
56110012147	Mg2+ binding site [ion binding]; other site
56110012148	G-X-G motif; other site
56110012149	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012150	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012151	active site
56110012152	phosphorylation site [posttranslational modification]
56110012153	intermolecular recognition site; other site
56110012154	dimerization interface [polypeptide binding]; other site
56110012155	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110012156	cyclase homology domain; Region: CHD; cd07302
56110012157	nucleotidyl binding site; other site
56110012158	metal binding site [ion binding]; metal-binding site
56110012159	dimer interface [polypeptide binding]; other site
56110012160	Protein kinase domain; Region: Pkinase; pfam00069
56110012161	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012162	active site
56110012163	ATP binding site [chemical binding]; other site
56110012164	substrate binding site [chemical binding]; other site
56110012165	activation loop (A-loop); other site
56110012166	AAA ATPase domain; Region: AAA_16; pfam13191
56110012167	Predicted ATPase [General function prediction only]; Region: COG3899
56110012168	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012169	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012170	PAS domain S-box; Region: sensory_box; TIGR00229
56110012171	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012172	PAS fold; Region: PAS_3; pfam08447
56110012173	putative active site [active]
56110012174	heme pocket [chemical binding]; other site
56110012175	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110012176	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012177	putative active site [active]
56110012178	heme pocket [chemical binding]; other site
56110012179	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012180	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110012181	putative active site [active]
56110012182	heme pocket [chemical binding]; other site
56110012183	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012184	putative active site [active]
56110012185	heme pocket [chemical binding]; other site
56110012186	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012187	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012188	dimer interface [polypeptide binding]; other site
56110012189	phosphorylation site [posttranslational modification]
56110012190	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012191	ATP binding site [chemical binding]; other site
56110012192	Mg2+ binding site [ion binding]; other site
56110012193	G-X-G motif; other site
56110012194	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110012195	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012196	active site
56110012197	phosphorylation site [posttranslational modification]
56110012198	intermolecular recognition site; other site
56110012199	dimerization interface [polypeptide binding]; other site
56110012200	Protein kinase domain; Region: Pkinase; pfam00069
56110012201	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012202	active site
56110012203	ATP binding site [chemical binding]; other site
56110012204	substrate binding site [chemical binding]; other site
56110012205	activation loop (A-loop); other site
56110012206	AAA ATPase domain; Region: AAA_16; pfam13191
56110012207	Predicted ATPase [General function prediction only]; Region: COG3899
56110012208	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012209	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012210	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110012211	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012212	putative active site [active]
56110012213	heme pocket [chemical binding]; other site
56110012214	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110012215	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012216	putative active site [active]
56110012217	heme pocket [chemical binding]; other site
56110012218	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012219	dimer interface [polypeptide binding]; other site
56110012220	phosphorylation site [posttranslational modification]
56110012221	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012222	ATP binding site [chemical binding]; other site
56110012223	Mg2+ binding site [ion binding]; other site
56110012224	G-X-G motif; other site
56110012225	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110012226	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012227	active site
56110012228	phosphorylation site [posttranslational modification]
56110012229	intermolecular recognition site; other site
56110012230	dimerization interface [polypeptide binding]; other site
56110012231	PAS domain S-box; Region: sensory_box; TIGR00229
56110012232	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012233	putative active site [active]
56110012234	heme pocket [chemical binding]; other site
56110012235	PAS domain S-box; Region: sensory_box; TIGR00229
56110012236	PAS domain; Region: PAS; smart00091
56110012237	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110012238	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110012239	metal binding site [ion binding]; metal-binding site
56110012240	active site
56110012241	I-site; other site
56110012242	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110012243	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
56110012244	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012245	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012246	dimer interface [polypeptide binding]; other site
56110012247	phosphorylation site [posttranslational modification]
56110012248	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012249	ATP binding site [chemical binding]; other site
56110012250	Mg2+ binding site [ion binding]; other site
56110012251	G-X-G motif; other site
56110012252	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
56110012253	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
56110012254	putative ligand binding site [chemical binding]; other site
56110012255	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012256	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012257	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
56110012258	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012259	ATP binding site [chemical binding]; other site
56110012260	G-X-G motif; other site
56110012261	Cache domain; Region: Cache_1; pfam02743
56110012262	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110012263	dimerization interface [polypeptide binding]; other site
56110012264	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110012265	cyclase homology domain; Region: CHD; cd07302
56110012266	nucleotidyl binding site; other site
56110012267	metal binding site [ion binding]; metal-binding site
56110012268	dimer interface [polypeptide binding]; other site
56110012269	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110012270	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110012271	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110012272	putative active site [active]
56110012273	putative NTP binding site [chemical binding]; other site
56110012274	putative nucleic acid binding site [nucleotide binding]; other site
56110012275	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110012276	CHASE domain; Region: CHASE; pfam03924
56110012277	Heme NO binding associated; Region: HNOBA; pfam07701
56110012278	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110012279	cyclase homology domain; Region: CHD; cd07302
56110012280	nucleotidyl binding site; other site
56110012281	metal binding site [ion binding]; metal-binding site
56110012282	dimer interface [polypeptide binding]; other site
56110012283	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
56110012284	Double zinc ribbon; Region: DZR; pfam12773
56110012285	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
56110012286	active site
56110012287	Cyanobacterial and plastid NDH-1 subunit M; Region: NdhM; pfam10664
56110012288	Tellurite resistance protein TerB; Region: TerB; cl17311
56110012289	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
56110012290	intracellular protease, PfpI family; Region: PfpI; TIGR01382
56110012291	proposed catalytic triad [active]
56110012292	conserved cys residue [active]
56110012293	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
56110012294	dinuclear metal binding motif [ion binding]; other site
56110012295	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
56110012296	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
56110012297	dimerization interface [polypeptide binding]; other site
56110012298	DPS ferroxidase diiron center [ion binding]; other site
56110012299	ion pore; other site
56110012300	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
56110012301	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110012302	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012303	active site
56110012304	phosphorylation site [posttranslational modification]
56110012305	intermolecular recognition site; other site
56110012306	dimerization interface [polypeptide binding]; other site
56110012307	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110012308	DNA binding residues [nucleotide binding]
56110012309	dimerization interface [polypeptide binding]; other site
56110012310	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012311	putative active site [active]
56110012312	PAS fold; Region: PAS_3; pfam08447
56110012313	heme pocket [chemical binding]; other site
56110012314	PAS domain; Region: PAS_9; pfam13426
56110012315	PAS fold; Region: PAS_4; pfam08448
56110012316	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012317	putative active site [active]
56110012318	heme pocket [chemical binding]; other site
56110012319	PAS domain S-box; Region: sensory_box; TIGR00229
56110012320	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012321	putative active site [active]
56110012322	heme pocket [chemical binding]; other site
56110012323	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012324	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012325	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012326	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012327	dimer interface [polypeptide binding]; other site
56110012328	phosphorylation site [posttranslational modification]
56110012329	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012330	ATP binding site [chemical binding]; other site
56110012331	Mg2+ binding site [ion binding]; other site
56110012332	G-X-G motif; other site
56110012333	Orange carotenoid protein, N-terminal; Region: Carot_N; pfam09150
56110012334	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012335	active site
56110012336	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012337	phosphorylation site [posttranslational modification]
56110012338	intermolecular recognition site; other site
56110012339	dimerization interface [polypeptide binding]; other site
56110012340	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012341	dimer interface [polypeptide binding]; other site
56110012342	phosphorylation site [posttranslational modification]
56110012343	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012344	ATP binding site [chemical binding]; other site
56110012345	Mg2+ binding site [ion binding]; other site
56110012346	G-X-G motif; other site
56110012347	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
56110012348	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110012349	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
56110012350	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110012351	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110012352	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
56110012353	metal binding site 2 [ion binding]; metal-binding site
56110012354	putative DNA binding helix; other site
56110012355	metal binding site 1 [ion binding]; metal-binding site
56110012356	dimer interface [polypeptide binding]; other site
56110012357	structural Zn2+ binding site [ion binding]; other site
56110012358	RNA polymerase sigma factor SigC; Validated; Region: PRK07598
56110012359	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110012360	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
56110012361	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110012362	DNA binding residues [nucleotide binding]
56110012363	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional; Region: PRK14619
56110012364	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
56110012365	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
56110012366	lipoyl synthase; Provisional; Region: PRK05481
56110012367	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
56110012368	FeS/SAM binding site; other site
56110012369	Domain of unknown function (DUF1802); Region: DUF1802; cl01755
56110012370	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
56110012371	Domain of unknown function (DUF4278); Region: DUF4278; pfam14105
56110012372	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
56110012373	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110012374	motif II; other site
56110012375	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
56110012376	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
56110012377	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110012378	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110012379	Peptidase_C39 like family; Region: Peptidase_C39_2; pfam13529
56110012380	putative active site [active]
56110012381	Domain of unknown function (DUF4394); Region: DUF4394; pfam14339
56110012382	Domain of unknown function (DUF4394); Region: DUF4394; pfam14339
56110012383	PBP superfamily domain; Region: PBP_like_2; cl17296
56110012384	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
56110012385	Domain of unknown function DUF20; Region: UPF0118; pfam01594
56110012386	Domain of unknown function DUF39; Region: DUF39; pfam01837
56110012387	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110012388	binding surface
56110012389	TPR motif; other site
56110012390	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110012391	TPR motif; other site
56110012392	binding surface
56110012393	Stress responsive A/B Barrel Domain; Region: Dabb; pfam07876
56110012394	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK05945
56110012395	L-aspartate oxidase; Provisional; Region: PRK06175
56110012396	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
56110012397	TPR repeat; Region: TPR_11; pfam13414
56110012398	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110012399	binding surface
56110012400	TPR motif; other site
56110012401	TPR repeat; Region: TPR_11; pfam13414
56110012402	TPR repeat; Region: TPR_11; pfam13414
56110012403	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110012404	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110012405	active site
56110012406	ATP binding site [chemical binding]; other site
56110012407	substrate binding site [chemical binding]; other site
56110012408	activation loop (A-loop); other site
56110012409	Protein of unknown function (DUF2811); Region: DUF2811; pfam10929
56110012410	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110012411	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012412	active site
56110012413	phosphorylation site [posttranslational modification]
56110012414	intermolecular recognition site; other site
56110012415	dimerization interface [polypeptide binding]; other site
56110012416	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110012417	DNA binding site [nucleotide binding]
56110012418	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012419	active site
56110012420	phosphorylation site [posttranslational modification]
56110012421	intermolecular recognition site; other site
56110012422	dimerization interface [polypeptide binding]; other site
56110012423	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012424	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012425	dimer interface [polypeptide binding]; other site
56110012426	phosphorylation site [posttranslational modification]
56110012427	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012428	ATP binding site [chemical binding]; other site
56110012429	Mg2+ binding site [ion binding]; other site
56110012430	G-X-G motif; other site
56110012431	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; pfam09912
56110012432	TPR repeat; Region: TPR_11; pfam13414
56110012433	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110012434	binding surface
56110012435	TPR motif; other site
56110012436	TPR repeat; Region: TPR_11; pfam13414
56110012437	TPR repeat; Region: TPR_11; pfam13414
56110012438	TPR repeat; Region: TPR_11; pfam13414
56110012439	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110012440	binding surface
56110012441	TPR motif; other site
56110012442	TPR repeat; Region: TPR_11; pfam13414
56110012443	Bacterial Ig-like domain; Region: Big_5; pfam13205
56110012444	NAD(P)H-quinone oxidoreductase subunit F; Validated; Region: PRK07390
56110012445	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110012446	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
56110012447	active site clefts [active]
56110012448	zinc binding site [ion binding]; other site
56110012449	dimer interface [polypeptide binding]; other site
56110012450	NAD(P)H-quinone oxidoreductase subunit M; Validated; Region: PRK07363
56110012451	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110012452	CO2 hydration protein (ChpXY); Region: ChpXY; cl10905
56110012453	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
56110012454	Fasciclin domain; Region: Fasciclin; pfam02469
56110012455	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
56110012456	Mitochondrial biogenesis AIM24; Region: AIM24; cl00884
56110012457	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
56110012458	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
56110012459	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
56110012460	ATP-grasp ribosomal peptide maturase, SAV_5884 family; Region: GRASP_SAV_5884; TIGR04187
56110012461	ATP-grasp domain; Region: ATP-grasp_4; cl17255
56110012462	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110012463	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110012464	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
56110012465	inhibitor binding site; inhibition site
56110012466	catalytic motif [active]
56110012467	Catalytic residue [active]
56110012468	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
56110012469	Uncharacterized conserved protein [Function unknown]; Region: COG2442
56110012470	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
56110012471	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
56110012472	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
56110012473	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
56110012474	ABC transporter; Region: ABC_tran_2; pfam12848
56110012475	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
56110012476	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
56110012477	putative active site [active]
56110012478	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
56110012479	Protein of unknown function (DUF3318); Region: DUF3318; pfam11780
56110012480	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
56110012481	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
56110012482	Ligand binding site; other site
56110012483	Putative Catalytic site; other site
56110012484	DXD motif; other site
56110012485	FO synthase subunit 2; Reviewed; Region: PRK07360
56110012486	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110012487	FeS/SAM binding site; other site
56110012488	Protein of unknown function (DUF3352); Region: DUF3352; pfam11832
56110012489	cytochrome c biogenesis protein; Region: ccsA; CHL00045
56110012490	cytochrome c biogenesis protein; Region: ccsA; CHL00045
56110012491	KGK domain; Region: KGK; pfam08872
56110012492	KGK domain; Region: KGK; pfam08872
56110012493	Peptidase S8 family domain in Protein convertases; Region: Peptidases_S8_Protein_convertases_Kexins_Furin-lik; cd04059
56110012494	calcium binding site 1 [ion binding]; other site
56110012495	active site
56110012496	catalytic triad [active]
56110012497	calcium binding site 2 [ion binding]; other site
56110012498	calcium binding site 3 [ion binding]; other site
56110012499	Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG4935
56110012500	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
56110012501	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110012502	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
56110012503	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
56110012504	Ligand Binding Site [chemical binding]; other site
56110012505	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
56110012506	Domain of unknown function (DUF4388); Region: DUF4388; pfam14332
56110012507	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012508	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012509	active site
56110012510	phosphorylation site [posttranslational modification]
56110012511	intermolecular recognition site; other site
56110012512	dimerization interface [polypeptide binding]; other site
56110012513	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012514	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012515	active site
56110012516	phosphorylation site [posttranslational modification]
56110012517	intermolecular recognition site; other site
56110012518	dimerization interface [polypeptide binding]; other site
56110012519	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
56110012520	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110012521	binding surface
56110012522	TPR repeat; Region: TPR_11; pfam13414
56110012523	TPR motif; other site
56110012524	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110012525	dimerization interface [polypeptide binding]; other site
56110012526	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110012527	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110012528	dimer interface [polypeptide binding]; other site
56110012529	putative CheW interface [polypeptide binding]; other site
56110012530	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110012531	putative binding surface; other site
56110012532	active site
56110012533	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
56110012534	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
56110012535	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012536	ATP binding site [chemical binding]; other site
56110012537	Mg2+ binding site [ion binding]; other site
56110012538	G-X-G motif; other site
56110012539	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
56110012540	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012541	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012542	active site
56110012543	phosphorylation site [posttranslational modification]
56110012544	intermolecular recognition site; other site
56110012545	dimerization interface [polypeptide binding]; other site
56110012546	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012547	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012548	active site
56110012549	phosphorylation site [posttranslational modification]
56110012550	intermolecular recognition site; other site
56110012551	dimerization interface [polypeptide binding]; other site
56110012552	PAS domain S-box; Region: sensory_box; TIGR00229
56110012553	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012554	dimer interface [polypeptide binding]; other site
56110012555	phosphorylation site [posttranslational modification]
56110012556	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012557	ATP binding site [chemical binding]; other site
56110012558	Mg2+ binding site [ion binding]; other site
56110012559	G-X-G motif; other site
56110012560	FOG: CBS domain [General function prediction only]; Region: COG0517
56110012561	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110012562	FOG: CBS domain [General function prediction only]; Region: COG0517
56110012563	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with a PAS domain, a GGDEF (DiGuanylate-Cyclase (DGC) domain, and a DUF1 domain downstream. PAS domains have been found to bind ligands, and to act...; Region: CBS_pair_PAS_GGDEF_DUF1_assoc; cd04611
56110012564	PAS fold; Region: PAS_4; pfam08448
56110012565	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012566	putative active site [active]
56110012567	heme pocket [chemical binding]; other site
56110012568	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012569	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110012570	putative active site [active]
56110012571	heme pocket [chemical binding]; other site
56110012572	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012573	putative active site [active]
56110012574	heme pocket [chemical binding]; other site
56110012575	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012576	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012577	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012578	PAS fold; Region: PAS_3; pfam08447
56110012579	putative active site [active]
56110012580	heme pocket [chemical binding]; other site
56110012581	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012582	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012583	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012584	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012585	dimer interface [polypeptide binding]; other site
56110012586	phosphorylation site [posttranslational modification]
56110012587	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012588	ATP binding site [chemical binding]; other site
56110012589	Mg2+ binding site [ion binding]; other site
56110012590	G-X-G motif; other site
56110012591	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110012592	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012593	active site
56110012594	phosphorylation site [posttranslational modification]
56110012595	intermolecular recognition site; other site
56110012596	dimerization interface [polypeptide binding]; other site
56110012597	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110012598	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110012599	TPR motif; other site
56110012600	binding surface
56110012601	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
56110012602	catalytic residue [active]
56110012603	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
56110012604	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110012605	Walker A/P-loop; other site
56110012606	ATP binding site [chemical binding]; other site
56110012607	Q-loop/lid; other site
56110012608	ABC transporter signature motif; other site
56110012609	Walker B; other site
56110012610	D-loop; other site
56110012611	H-loop/switch region; other site
56110012612	ABC transporter; Region: ABC_tran_2; pfam12848
56110012613	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
56110012614	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
56110012615	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
56110012616	active site
56110012617	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
56110012618	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
56110012619	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
56110012620	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012621	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012622	active site
56110012623	phosphorylation site [posttranslational modification]
56110012624	intermolecular recognition site; other site
56110012625	dimerization interface [polypeptide binding]; other site
56110012626	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012627	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012628	PAS domain S-box; Region: sensory_box; TIGR00229
56110012629	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012630	putative active site [active]
56110012631	heme pocket [chemical binding]; other site
56110012632	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110012633	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012634	putative active site [active]
56110012635	heme pocket [chemical binding]; other site
56110012636	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012637	dimer interface [polypeptide binding]; other site
56110012638	phosphorylation site [posttranslational modification]
56110012639	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012640	ATP binding site [chemical binding]; other site
56110012641	Mg2+ binding site [ion binding]; other site
56110012642	G-X-G motif; other site
56110012643	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
56110012644	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
56110012645	Uncharacterized subfamily of  glycoside hydrolase family 57 (GH57); Region: GH57N_like_1; cd10798
56110012646	active site
56110012647	catalytic site [active]
56110012648	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110012649	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012650	PAS domain; Region: PAS_9; pfam13426
56110012651	putative active site [active]
56110012652	heme pocket [chemical binding]; other site
56110012653	PAS domain S-box; Region: sensory_box; TIGR00229
56110012654	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012655	putative active site [active]
56110012656	heme pocket [chemical binding]; other site
56110012657	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012658	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012659	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
56110012660	Histidine kinase; Region: HisKA_2; pfam07568
56110012661	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012662	ATP binding site [chemical binding]; other site
56110012663	Mg2+ binding site [ion binding]; other site
56110012664	G-X-G motif; other site
56110012665	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110012666	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012667	active site
56110012668	phosphorylation site [posttranslational modification]
56110012669	intermolecular recognition site; other site
56110012670	dimerization interface [polypeptide binding]; other site
56110012671	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012672	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012673	dimer interface [polypeptide binding]; other site
56110012674	phosphorylation site [posttranslational modification]
56110012675	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012676	ATP binding site [chemical binding]; other site
56110012677	Mg2+ binding site [ion binding]; other site
56110012678	G-X-G motif; other site
56110012679	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
56110012680	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110012681	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
56110012682	Walker A/P-loop; other site
56110012683	ATP binding site [chemical binding]; other site
56110012684	Q-loop/lid; other site
56110012685	ABC transporter signature motif; other site
56110012686	Walker B; other site
56110012687	D-loop; other site
56110012688	H-loop/switch region; other site
56110012689	Topoisomerase II-associated protein PAT1; Region: PAT1; pfam09770
56110012690	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
56110012691	ATP-grasp domain; Region: ATP-grasp; pfam02222
56110012692	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
56110012693	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
56110012694	domain interfaces; other site
56110012695	active site
56110012696	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
56110012697	AMP-binding enzyme; Region: AMP-binding; pfam00501
56110012698	acyl-activating enzyme (AAE) consensus motif; other site
56110012699	AMP binding site [chemical binding]; other site
56110012700	active site
56110012701	CoA binding site [chemical binding]; other site
56110012702	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
56110012703	MviN-like protein; Region: MVIN; pfam03023
56110012704	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
56110012705	polyphosphate:AMP phosphotransferase; Region: poly_P_AMP_trns; TIGR03708
56110012706	Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971
56110012707	Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971
56110012708	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110012709	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012710	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012711	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012712	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012713	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012714	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012715	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
56110012716	putative active site [active]
56110012717	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
56110012718	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
56110012719	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110012720	Walker A/P-loop; other site
56110012721	ATP binding site [chemical binding]; other site
56110012722	Q-loop/lid; other site
56110012723	ABC transporter signature motif; other site
56110012724	Walker B; other site
56110012725	D-loop; other site
56110012726	H-loop/switch region; other site
56110012727	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
56110012728	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
56110012729	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
56110012730	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012731	PAS fold; Region: PAS_3; pfam08447
56110012732	putative active site [active]
56110012733	heme pocket [chemical binding]; other site
56110012734	PAS fold; Region: PAS_4; pfam08448
56110012735	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
56110012736	putative active site [active]
56110012737	heme pocket [chemical binding]; other site
56110012738	PAS fold; Region: PAS_4; pfam08448
56110012739	PAS fold; Region: PAS_3; pfam08447
56110012740	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012741	heme pocket [chemical binding]; other site
56110012742	putative active site [active]
56110012743	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012744	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012745	ATP binding site [chemical binding]; other site
56110012746	Mg2+ binding site [ion binding]; other site
56110012747	G-X-G motif; other site
56110012748	MgtC family; Region: MgtC; pfam02308
56110012749	Domain of unknown function (DUF1830); Region: DUF1830; pfam08865
56110012750	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110012751	putative binding surface; other site
56110012752	active site
56110012753	mycothiol synthase; Region: mycothiol_MshD; TIGR03448
56110012754	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110012755	Coenzyme A binding pocket [chemical binding]; other site
56110012756	M28 Zn-Peptidases; Region: M28_like_1; cd05640
56110012757	Peptidase family M28; Region: Peptidase_M28; pfam04389
56110012758	metal binding site [ion binding]; metal-binding site
56110012759	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
56110012760	PAS domain S-box; Region: sensory_box; TIGR00229
56110012761	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012762	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012763	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110012764	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110012765	metal binding site [ion binding]; metal-binding site
56110012766	active site
56110012767	I-site; other site
56110012768	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110012769	Predicted membrane protein/domain [Function unknown]; Region: COG1714
56110012770	Uncharacterized membrane protein [Function unknown]; Region: SpoIIM; COG1300
56110012771	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
56110012772	Protein of unknown function DUF58; Region: DUF58; pfam01882
56110012773	von Willebrand factor (vWF) type A domain; Region: VWA; smart00327
56110012774	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
56110012775	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110012776	Walker A motif; other site
56110012777	ATP binding site [chemical binding]; other site
56110012778	Walker B motif; other site
56110012779	arginine finger; other site
56110012780	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
56110012781	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
56110012782	Protein of unknown function (DUF550); Region: DUF550; pfam04447
56110012783	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
56110012784	putative active site [active]
56110012785	homotetrameric interface [polypeptide binding]; other site
56110012786	metal binding site [ion binding]; metal-binding site
56110012787	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
56110012788	Uncharacterized conserved protein [Function unknown]; Region: COG3339
56110012789	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110012790	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110012791	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012792	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012793	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110012794	NADH dehydrogenase subunit J; Provisional; Region: PRK12494
56110012795	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
56110012796	NADH dehydrogenase subunit K; Region: ndhK; CHL00023
56110012797	NADH dehydrogenase subunit 3; Region: ndhC; CHL00022
56110012798	Rubredoxin [Energy production and conversion]; Region: COG1773
56110012799	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
56110012800	iron binding site [ion binding]; other site
56110012801	Ycf48-like protein; Provisional; Region: PRK13684
56110012802	cytochrome b559 subunit alpha; Provisional; Region: psbE; PRK02557
56110012803	Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits; Region: Cytochrom_B559; pfam00283
56110012804	Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit; Region: Cytochrom_B559a; pfam00284
56110012805	cytochrome b559 subunit beta; Provisional; Region: psbF; PRK02561
56110012806	PsbL protein; Region: PsbL; cl03581
56110012807	photosystem II reaction center protein J; Provisional; Region: PRK02565
56110012808	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110012809	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
56110012810	Fatty acid desaturase; Region: FA_desaturase; pfam00487
56110012811	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cd01060
56110012812	putative di-iron ligands [ion binding]; other site
56110012813	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
56110012814	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
56110012815	GDP-Fucose binding site [chemical binding]; other site
56110012816	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012817	GAF domain; Region: GAF; pfam01590
56110012818	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012819	PAS fold; Region: PAS_3; pfam08447
56110012820	putative active site [active]
56110012821	heme pocket [chemical binding]; other site
56110012822	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110012823	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110012824	metal binding site [ion binding]; metal-binding site
56110012825	active site
56110012826	I-site; other site
56110012827	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110012828	HsdM N-terminal domain; Region: HsdM_N; pfam12161
56110012829	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
56110012830	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
56110012831	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
56110012832	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
56110012833	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
56110012834	RsbT co-antagonist protein rsbRD N-terminal domain; Region: RsbRD_N; pfam14361
56110012835	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012836	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012837	phosphorylation site [posttranslational modification]
56110012838	dimer interface [polypeptide binding]; other site
56110012839	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012840	ATP binding site [chemical binding]; other site
56110012841	Mg2+ binding site [ion binding]; other site
56110012842	G-X-G motif; other site
56110012843	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110012844	putative active site [active]
56110012845	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
56110012846	putative active site [active]
56110012847	Mo-dependent nitrogenase C-terminus; Region: Mo-nitro_C; pfam06967
56110012848	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
56110012849	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
56110012850	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
56110012851	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
56110012852	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
56110012853	substrate binding pocket [chemical binding]; other site
56110012854	chain length determination region; other site
56110012855	substrate-Mg2+ binding site; other site
56110012856	catalytic residues [active]
56110012857	aspartate-rich region 1; other site
56110012858	active site lid residues [active]
56110012859	aspartate-rich region 2; other site
56110012860	glutamate racemase; Provisional; Region: PRK00865
56110012861	AMIN domain; Region: AMIN; pfam11741
56110012862	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
56110012863	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
56110012864	active site
56110012865	metal binding site [ion binding]; metal-binding site
56110012866	LL-diaminopimelate aminotransferase; Provisional; Region: PRK09276
56110012867	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110012868	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110012869	homodimer interface [polypeptide binding]; other site
56110012870	catalytic residue [active]
56110012871	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110012872	anti sigma factor interaction site; other site
56110012873	regulatory phosphorylation site [posttranslational modification]; other site
56110012874	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
56110012875	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
56110012876	B12 binding site [chemical binding]; other site
56110012877	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110012878	FeS/SAM binding site; other site
56110012879	Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; cl02090
56110012880	radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936
56110012881	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
56110012882	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
56110012883	homodimer interface [polypeptide binding]; other site
56110012884	oligonucleotide binding site [chemical binding]; other site
56110012885	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
56110012886	RNA/DNA hybrid binding site [nucleotide binding]; other site
56110012887	active site
56110012888	NACHT domain; Region: NACHT; pfam05729
56110012889	AAA domain; Region: AAA_14; pfam13173
56110012890	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
56110012891	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
56110012892	dimerization interface [polypeptide binding]; other site
56110012893	putative ATP binding site [chemical binding]; other site
56110012894	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
56110012895	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
56110012896	bifunctional pantoate ligase/cytidylate kinase; Provisional; Region: PRK13477
56110012897	Pantoate-beta-alanine ligase; Region: PanC; cd00560
56110012898	active site
56110012899	ATP-binding site [chemical binding]; other site
56110012900	pantoate-binding site; other site
56110012901	HXXH motif; other site
56110012902	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
56110012903	CMP-binding site; other site
56110012904	The sites determining sugar specificity; other site
56110012905	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
56110012906	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
56110012907	NodB motif; other site
56110012908	active site
56110012909	catalytic site [active]
56110012910	metal binding site [ion binding]; metal-binding site
56110012911	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110012912	structural tetrad; other site
56110012913	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110012914	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110012915	structural tetrad; other site
56110012916	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012917	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110012918	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110012919	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110012920	dimer interface [polypeptide binding]; other site
56110012921	phosphorylation site [posttranslational modification]
56110012922	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110012923	ATP binding site [chemical binding]; other site
56110012924	Mg2+ binding site [ion binding]; other site
56110012925	G-X-G motif; other site
56110012926	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012927	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012928	active site
56110012929	phosphorylation site [posttranslational modification]
56110012930	intermolecular recognition site; other site
56110012931	dimerization interface [polypeptide binding]; other site
56110012932	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012933	active site
56110012934	phosphorylation site [posttranslational modification]
56110012935	intermolecular recognition site; other site
56110012936	dimerization interface [polypeptide binding]; other site
56110012937	Response regulator receiver domain; Region: Response_reg; pfam00072
56110012938	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110012939	active site
56110012940	phosphorylation site [posttranslational modification]
56110012941	intermolecular recognition site; other site
56110012942	dimerization interface [polypeptide binding]; other site
56110012943	PAS fold; Region: PAS_4; pfam08448
56110012944	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110012945	putative active site [active]
56110012946	heme pocket [chemical binding]; other site
56110012947	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110012948	GAF domain; Region: GAF; pfam01590
56110012949	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110012950	cyclase homology domain; Region: CHD; cd07302
56110012951	nucleotidyl binding site; other site
56110012952	metal binding site [ion binding]; metal-binding site
56110012953	dimer interface [polypeptide binding]; other site
56110012954	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
56110012955	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
56110012956	active site
56110012957	dimer interface [polypeptide binding]; other site
56110012958	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
56110012959	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
56110012960	active site
56110012961	FMN binding site [chemical binding]; other site
56110012962	substrate binding site [chemical binding]; other site
56110012963	3Fe-4S cluster binding site [ion binding]; other site
56110012964	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
56110012965	domain interface; other site
56110012966	Cupin domain; Region: Cupin_2; cl17218
56110012967	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
56110012968	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
56110012969	S17 interaction site [polypeptide binding]; other site
56110012970	S8 interaction site; other site
56110012971	16S rRNA interaction site [nucleotide binding]; other site
56110012972	streptomycin interaction site [chemical binding]; other site
56110012973	23S rRNA interaction site [nucleotide binding]; other site
56110012974	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
56110012975	ribosomal protein S7; Region: rps7; CHL00053
56110012976	elongation factor G; Reviewed; Region: PRK00007
56110012977	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
56110012978	G1 box; other site
56110012979	putative GEF interaction site [polypeptide binding]; other site
56110012980	GTP/Mg2+ binding site [chemical binding]; other site
56110012981	Switch I region; other site
56110012982	G2 box; other site
56110012983	G3 box; other site
56110012984	Switch II region; other site
56110012985	G4 box; other site
56110012986	G5 box; other site
56110012987	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
56110012988	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
56110012989	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
56110012990	elongation factor Tu; Region: tufA; CHL00071
56110012991	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
56110012992	G1 box; other site
56110012993	GEF interaction site [polypeptide binding]; other site
56110012994	GTP/Mg2+ binding site [chemical binding]; other site
56110012995	Switch I region; other site
56110012996	G2 box; other site
56110012997	G3 box; other site
56110012998	Switch II region; other site
56110012999	G4 box; other site
56110013000	G5 box; other site
56110013001	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
56110013002	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
56110013003	Antibiotic Binding Site [chemical binding]; other site
56110013004	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
56110013005	Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only]; Region: COG2802
56110013006	prephenate dehydratase; Provisional; Region: PRK11898
56110013007	Prephenate dehydratase; Region: PDT; pfam00800
56110013008	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
56110013009	putative L-Phe binding site [chemical binding]; other site
56110013010	Protein of unknown function (DUF1997); Region: DUF1997; pfam09366
56110013011	Protein of unknown function (DUF1997); Region: DUF1997; pfam09366
56110013012	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110013013	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110013014	Homeodomain-like domain; Region: HTH_32; pfam13565
56110013015	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
56110013016	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
56110013017	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013018	active site
56110013019	phosphorylation site [posttranslational modification]
56110013020	intermolecular recognition site; other site
56110013021	dimerization interface [polypeptide binding]; other site
56110013022	CheB methylesterase; Region: CheB_methylest; pfam01339
56110013023	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
56110013024	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
56110013025	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
56110013026	PAS domain; Region: PAS_9; pfam13426
56110013027	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
56110013028	protein binding surface [polypeptide binding]; other site
56110013029	HEAT repeats; Region: HEAT_2; pfam13646
56110013030	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
56110013031	protein binding surface [polypeptide binding]; other site
56110013032	HEAT repeats; Region: HEAT_2; pfam13646
56110013033	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
56110013034	HEAT repeats; Region: HEAT_2; pfam13646
56110013035	HEAT repeats; Region: HEAT_2; pfam13646
56110013036	HEAT repeats; Region: HEAT_2; pfam13646
56110013037	HEAT repeats; Region: HEAT_2; pfam13646
56110013038	HEAT repeats; Region: HEAT_2; pfam13646
56110013039	HEAT repeats; Region: HEAT_2; pfam13646
56110013040	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110013041	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110013042	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110013043	dimer interface [polypeptide binding]; other site
56110013044	putative CheW interface [polypeptide binding]; other site
56110013045	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110013046	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
56110013047	Response regulator receiver domain; Region: Response_reg; pfam00072
56110013048	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013049	active site
56110013050	phosphorylation site [posttranslational modification]
56110013051	intermolecular recognition site; other site
56110013052	dimerization interface [polypeptide binding]; other site
56110013053	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
56110013054	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110013055	active site
56110013056	motif I; other site
56110013057	motif II; other site
56110013058	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110013059	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
56110013060	DALR anticodon binding domain; Region: DALR_1; smart00836
56110013061	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110013062	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110013063	putative switch regulator; other site
56110013064	non-specific DNA interactions [nucleotide binding]; other site
56110013065	DNA binding site [nucleotide binding]
56110013066	sequence specific DNA binding site [nucleotide binding]; other site
56110013067	putative cAMP binding site [chemical binding]; other site
56110013068	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013069	PAS domain; Region: PAS_9; pfam13426
56110013070	putative active site [active]
56110013071	heme pocket [chemical binding]; other site
56110013072	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110013073	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110013074	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110013075	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110013076	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013077	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110013078	putative active site [active]
56110013079	heme pocket [chemical binding]; other site
56110013080	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013081	dimer interface [polypeptide binding]; other site
56110013082	phosphorylation site [posttranslational modification]
56110013083	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013084	ATP binding site [chemical binding]; other site
56110013085	Mg2+ binding site [ion binding]; other site
56110013086	G-X-G motif; other site
56110013087	PBP superfamily domain; Region: PBP_like_2; cl17296
56110013088	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110013089	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110013090	active site
56110013091	ATP binding site [chemical binding]; other site
56110013092	substrate binding site [chemical binding]; other site
56110013093	activation loop (A-loop); other site
56110013094	LysR transcriptional regulator; Provisional; Region: rbcR; CHL00180
56110013095	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
56110013096	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
56110013097	putative dimerization interface [polypeptide binding]; other site
56110013098	Predicted membrane protein [Function unknown]; Region: COG4094
56110013099	CHASE3 domain; Region: CHASE3; pfam05227
56110013100	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110013101	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110013102	dimer interface [polypeptide binding]; other site
56110013103	putative CheW interface [polypeptide binding]; other site
56110013104	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
56110013105	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110013106	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110013107	dimer interface [polypeptide binding]; other site
56110013108	putative CheW interface [polypeptide binding]; other site
56110013109	CHASE3 domain; Region: CHASE3; pfam05227
56110013110	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110013111	dimer interface [polypeptide binding]; other site
56110013112	putative CheW interface [polypeptide binding]; other site
56110013113	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
56110013114	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
56110013115	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
56110013116	Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138
56110013117	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110013118	S-adenosylmethionine binding site [chemical binding]; other site
56110013119	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013120	binding surface
56110013121	TPR repeat; Region: TPR_11; pfam13414
56110013122	TPR motif; other site
56110013123	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110013124	Response regulator receiver domain; Region: Response_reg; pfam00072
56110013125	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013126	active site
56110013127	phosphorylation site [posttranslational modification]
56110013128	intermolecular recognition site; other site
56110013129	dimerization interface [polypeptide binding]; other site
56110013130	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
56110013131	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
56110013132	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
56110013133	N-acetyl-D-glucosamine binding site [chemical binding]; other site
56110013134	catalytic residue [active]
56110013135	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110013136	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110013137	S-adenosylmethionine binding site [chemical binding]; other site
56110013138	multifunctional aminopeptidase A; Provisional; Region: PRK00913
56110013139	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
56110013140	interface (dimer of trimers) [polypeptide binding]; other site
56110013141	Substrate-binding/catalytic site; other site
56110013142	Zn-binding sites [ion binding]; other site
56110013143	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
56110013144	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
56110013145	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
56110013146	active site
56110013147	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
56110013148	Cupin domain; Region: Cupin_2; pfam07883
56110013149	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110013150	GAF domain; Region: GAF; pfam01590
56110013151	PAS domain S-box; Region: sensory_box; TIGR00229
56110013152	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013153	putative active site [active]
56110013154	heme pocket [chemical binding]; other site
56110013155	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110013156	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013157	putative active site [active]
56110013158	heme pocket [chemical binding]; other site
56110013159	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110013160	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110013161	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013162	PAS fold; Region: PAS_3; pfam08447
56110013163	putative active site [active]
56110013164	heme pocket [chemical binding]; other site
56110013165	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013166	PAS fold; Region: PAS_3; pfam08447
56110013167	putative active site [active]
56110013168	heme pocket [chemical binding]; other site
56110013169	PAS fold; Region: PAS_4; pfam08448
56110013170	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110013171	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013172	dimer interface [polypeptide binding]; other site
56110013173	phosphorylation site [posttranslational modification]
56110013174	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013175	ATP binding site [chemical binding]; other site
56110013176	Mg2+ binding site [ion binding]; other site
56110013177	G-X-G motif; other site
56110013178	Response regulator receiver domain; Region: Response_reg; pfam00072
56110013179	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013180	active site
56110013181	phosphorylation site [posttranslational modification]
56110013182	intermolecular recognition site; other site
56110013183	dimerization interface [polypeptide binding]; other site
56110013184	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110013185	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013186	active site
56110013187	phosphorylation site [posttranslational modification]
56110013188	intermolecular recognition site; other site
56110013189	dimerization interface [polypeptide binding]; other site
56110013190	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110013191	putative binding surface; other site
56110013192	active site
56110013193	Response regulator receiver domain; Region: Response_reg; pfam00072
56110013194	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013195	active site
56110013196	phosphorylation site [posttranslational modification]
56110013197	intermolecular recognition site; other site
56110013198	dimerization interface [polypeptide binding]; other site
56110013199	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110013200	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013201	putative active site [active]
56110013202	heme pocket [chemical binding]; other site
56110013203	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013204	dimer interface [polypeptide binding]; other site
56110013205	phosphorylation site [posttranslational modification]
56110013206	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013207	ATP binding site [chemical binding]; other site
56110013208	Mg2+ binding site [ion binding]; other site
56110013209	G-X-G motif; other site
56110013210	Response regulator receiver domain; Region: Response_reg; pfam00072
56110013211	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013212	active site
56110013213	phosphorylation site [posttranslational modification]
56110013214	intermolecular recognition site; other site
56110013215	dimerization interface [polypeptide binding]; other site
56110013216	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110013217	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013218	dimer interface [polypeptide binding]; other site
56110013219	phosphorylation site [posttranslational modification]
56110013220	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013221	ATP binding site [chemical binding]; other site
56110013222	Mg2+ binding site [ion binding]; other site
56110013223	G-X-G motif; other site
56110013224	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110013225	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013226	active site
56110013227	phosphorylation site [posttranslational modification]
56110013228	intermolecular recognition site; other site
56110013229	dimerization interface [polypeptide binding]; other site
56110013230	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110013231	DNA binding site [nucleotide binding]
56110013232	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110013233	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013234	dimer interface [polypeptide binding]; other site
56110013235	phosphorylation site [posttranslational modification]
56110013236	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013237	ATP binding site [chemical binding]; other site
56110013238	Mg2+ binding site [ion binding]; other site
56110013239	G-X-G motif; other site
56110013240	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
56110013241	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
56110013242	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110013243	dimer interface [polypeptide binding]; other site
56110013244	conserved gate region; other site
56110013245	putative PBP binding loops; other site
56110013246	ABC-ATPase subunit interface; other site
56110013247	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110013248	dimer interface [polypeptide binding]; other site
56110013249	conserved gate region; other site
56110013250	putative PBP binding loops; other site
56110013251	ABC-ATPase subunit interface; other site
56110013252	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
56110013253	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
56110013254	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110013255	Major Facilitator Superfamily; Region: MFS_1; pfam07690
56110013256	putative substrate translocation pore; other site
56110013257	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK08579
56110013258	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
56110013259	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
56110013260	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
56110013261	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
56110013262	putative active site [active]
56110013263	putative substrate binding site [chemical binding]; other site
56110013264	putative cosubstrate binding site; other site
56110013265	catalytic site [active]
56110013266	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
56110013267	YibE/F-like protein; Region: YibE_F; cl02259
56110013268	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
56110013269	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
56110013270	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
56110013271	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110013272	Walker A/P-loop; other site
56110013273	ATP binding site [chemical binding]; other site
56110013274	Q-loop/lid; other site
56110013275	ABC transporter signature motif; other site
56110013276	Walker B; other site
56110013277	D-loop; other site
56110013278	H-loop/switch region; other site
56110013279	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
56110013280	S-layer homology domain; Region: SLH; pfam00395
56110013281	S-layer homology domain; Region: SLH; pfam00395
56110013282	S-layer homology domain; Region: SLH; pfam00395
56110013283	S-layer homology domain; Region: SLH; pfam00395
56110013284	S-layer homology domain; Region: SLH; pfam00395
56110013285	PAS domain S-box; Region: sensory_box; TIGR00229
56110013286	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013287	putative active site [active]
56110013288	heme pocket [chemical binding]; other site
56110013289	PAS fold; Region: PAS_4; pfam08448
56110013290	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110013291	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110013292	metal binding site [ion binding]; metal-binding site
56110013293	active site
56110013294	I-site; other site
56110013295	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110013296	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
56110013297	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
56110013298	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
56110013299	active site
56110013300	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
56110013301	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110013302	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013303	putative active site [active]
56110013304	heme pocket [chemical binding]; other site
56110013305	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013306	putative active site [active]
56110013307	heme pocket [chemical binding]; other site
56110013308	PAS domain S-box; Region: sensory_box; TIGR00229
56110013309	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013310	putative active site [active]
56110013311	heme pocket [chemical binding]; other site
56110013312	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013313	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110013314	putative active site [active]
56110013315	heme pocket [chemical binding]; other site
56110013316	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013317	putative active site [active]
56110013318	heme pocket [chemical binding]; other site
56110013319	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013320	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110013321	putative active site [active]
56110013322	heme pocket [chemical binding]; other site
56110013323	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013324	putative active site [active]
56110013325	heme pocket [chemical binding]; other site
56110013326	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110013327	GAF domain; Region: GAF_2; pfam13185
56110013328	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110013329	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013330	dimer interface [polypeptide binding]; other site
56110013331	phosphorylation site [posttranslational modification]
56110013332	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013333	ATP binding site [chemical binding]; other site
56110013334	Mg2+ binding site [ion binding]; other site
56110013335	G-X-G motif; other site
56110013336	Response regulator receiver domain; Region: Response_reg; pfam00072
56110013337	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013338	active site
56110013339	phosphorylation site [posttranslational modification]
56110013340	intermolecular recognition site; other site
56110013341	dimerization interface [polypeptide binding]; other site
56110013342	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
56110013343	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
56110013344	substrate binding site [chemical binding]; other site
56110013345	hexamer interface [polypeptide binding]; other site
56110013346	metal binding site [ion binding]; metal-binding site
56110013347	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
56110013348	active site
56110013349	catalytic residues [active]
56110013350	Transcriptional regulator [Transcription]; Region: LytR; COG1316
56110013351	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
56110013352	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110013353	Sec-independent translocase component C; Provisional; Region: tatC; CHL00182
56110013354	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013355	PAS fold; Region: PAS_3; pfam08447
56110013356	putative active site [active]
56110013357	heme pocket [chemical binding]; other site
56110013358	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110013359	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013360	dimer interface [polypeptide binding]; other site
56110013361	phosphorylation site [posttranslational modification]
56110013362	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013363	ATP binding site [chemical binding]; other site
56110013364	Mg2+ binding site [ion binding]; other site
56110013365	G-X-G motif; other site
56110013366	Protein of unknown function (DUF3067); Region: DUF3067; pfam11267
56110013367	cytochrome b6-f complex iron-sulfur subunit; Provisional; Region: PRK13474
56110013368	Cytochrome B6-F complex Fe-S subunit; Region: CytB6-F_Fe-S; pfam08802
56110013369	Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The cytochrome b6f complex from Mastigocladus laminosus, a thermophilic cyanobacterium; Region: Rieske_cytochrome_b6f; cd03471
56110013370	cytochrome b subunit interaction site [polypeptide binding]; other site
56110013371	[2Fe-2S] cluster binding site [ion binding]; other site
56110013372	apocytochrome f; Reviewed; Region: PRK02693
56110013373	cytochrome f; Region: petA; CHL00037
56110013374	Conserved nitrate reductase-associated protein (Nitr_red_assoc); Region: Nitr_red_assoc; pfam09655
56110013375	haloalkane dehalogenase; Provisional; Region: PRK03592
56110013376	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
56110013377	photosystem II protein PsbQ; Region: PS_II_psbQ_bact; TIGR03042
56110013378	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
56110013379	hydroxyglutarate oxidase; Provisional; Region: PRK11728
56110013380	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110013381	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110013382	phosphopeptide binding site; other site
56110013383	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110013384	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110013385	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110013386	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
56110013387	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
56110013388	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
56110013389	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110013390	P-loop; other site
56110013391	Magnesium ion binding site [ion binding]; other site
56110013392	hydrolase, alpha/beta fold family protein; Region: PLN02824
56110013393	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110013394	substrate binding site [chemical binding]; other site
56110013395	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110013396	activation loop (A-loop); other site
56110013397	Caspase domain; Region: Peptidase_C14; pfam00656
56110013398	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110013399	phosphopeptide binding site; other site
56110013400	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110013401	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110013402	active site
56110013403	ATP binding site [chemical binding]; other site
56110013404	substrate binding site [chemical binding]; other site
56110013405	activation loop (A-loop); other site
56110013406	TPR repeat; Region: TPR_11; pfam13414
56110013407	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013408	TPR motif; other site
56110013409	binding surface
56110013410	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013411	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013412	binding surface
56110013413	TPR motif; other site
56110013414	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110013415	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110013416	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110013417	active site
56110013418	ATP binding site [chemical binding]; other site
56110013419	substrate binding site [chemical binding]; other site
56110013420	activation loop (A-loop); other site
56110013421	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110013422	TPR motif; other site
56110013423	binding surface
56110013424	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110013425	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013426	TPR motif; other site
56110013427	binding surface
56110013428	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013429	binding surface
56110013430	TPR motif; other site
56110013431	TPR repeat; Region: TPR_11; pfam13414
56110013432	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110013433	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110013434	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110013435	active site
56110013436	ATP binding site [chemical binding]; other site
56110013437	substrate binding site [chemical binding]; other site
56110013438	activation loop (A-loop); other site
56110013439	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110013440	phosphopeptide binding site; other site
56110013441	Protein phosphatase 2C; Region: PP2C; pfam00481
56110013442	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
56110013443	active site
56110013444	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
56110013445	Double zinc ribbon; Region: DZR; pfam12773
56110013446	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110013447	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110013448	phosphopeptide binding site; other site
56110013449	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
56110013450	metal ion-dependent adhesion site (MIDAS); other site
56110013451	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
56110013452	metal ion-dependent adhesion site (MIDAS); other site
56110013453	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
56110013454	Protein of unknown function (DUF4101); Region: DUF4101; pfam13355
56110013455	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
56110013456	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
56110013457	metal ion-dependent adhesion site (MIDAS); other site
56110013458	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110013459	AAA-like domain; Region: AAA_10; pfam12846
56110013460	Walker A motif; other site
56110013461	ATP binding site [chemical binding]; other site
56110013462	Walker B motif; other site
56110013463	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
56110013464	active site
56110013465	catalytic residues [active]
56110013466	DNA binding site [nucleotide binding]
56110013467	Int/Topo IB signature motif; other site
56110013468	NACHT domain; Region: NACHT; pfam05729
56110013469	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110013470	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110013471	active site
56110013472	ATP binding site [chemical binding]; other site
56110013473	substrate binding site [chemical binding]; other site
56110013474	activation loop (A-loop); other site
56110013475	TPR repeat; Region: TPR_11; pfam13414
56110013476	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013477	binding surface
56110013478	TPR motif; other site
56110013479	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110013480	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
56110013481	Walker A motif; other site
56110013482	ATP binding site [chemical binding]; other site
56110013483	CHAT domain; Region: CHAT; cl17868
56110013484	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110013485	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110013486	structural tetrad; other site
56110013487	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
56110013488	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
56110013489	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110013490	dimerization interface [polypeptide binding]; other site
56110013491	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
56110013492	putative active site [active]
56110013493	heme pocket [chemical binding]; other site
56110013494	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013495	dimer interface [polypeptide binding]; other site
56110013496	phosphorylation site [posttranslational modification]
56110013497	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013498	ATP binding site [chemical binding]; other site
56110013499	Mg2+ binding site [ion binding]; other site
56110013500	G-X-G motif; other site
56110013501	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
56110013502	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110013503	dimerization interface [polypeptide binding]; other site
56110013504	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013505	dimer interface [polypeptide binding]; other site
56110013506	phosphorylation site [posttranslational modification]
56110013507	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013508	ATP binding site [chemical binding]; other site
56110013509	Mg2+ binding site [ion binding]; other site
56110013510	G-X-G motif; other site
56110013511	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110013512	Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; Region: CysPc; cl00051
56110013513	catalytic site [active]
56110013514	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
56110013515	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110013516	CHAT domain; Region: CHAT; cl17868
56110013517	TPR repeat; Region: TPR_11; pfam13414
56110013518	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013519	binding surface
56110013520	TPR motif; other site
56110013521	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013522	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110013523	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110013524	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
56110013525	active site
56110013526	catalytic residues [active]
56110013527	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
56110013528	Calx-beta domain; Region: Calx-beta; cl02522
56110013529	A bacterial subgroup of the C-type lectin-like (CTLD) domain; a subgroup of bacterial protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins; Region: CLECT_VCBS; cd03603
56110013530	ligand binding surface [chemical binding]; other site
56110013531	Calx-beta domain; Region: Calx-beta; cl02522
56110013532	A bacterial subgroup of the C-type lectin-like (CTLD) domain; a subgroup of bacterial protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins; Region: CLECT_VCBS; cd03603
56110013533	ligand binding surface [chemical binding]; other site
56110013534	Calx-beta domain; Region: Calx-beta; cl02522
56110013535	Calx-beta domain; Region: Calx-beta; cl02522
56110013536	Beta-propeller repeat; Region: SBBP; pfam06739
56110013537	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110013538	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
56110013539	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
56110013540	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
56110013541	Surface antigen; Region: Bac_surface_Ag; pfam01103
56110013542	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013543	TPR motif; other site
56110013544	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013545	binding surface
56110013546	CHAT domain; Region: CHAT; cl17868
56110013547	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110013548	CHAT domain; Region: CHAT; cl17868
56110013549	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110013550	CHASE2 domain; Region: CHASE2; pfam05226
56110013551	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110013552	Protein of unknown function (DUF952); Region: DUF952; cl01393
56110013553	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110013554	DNA binding residues [nucleotide binding]
56110013555	Predicted hydrocarbon binding protein (contains V4R domain) [General function prediction only]; Region: COG1719
56110013556	V4R domain; Region: V4R; pfam02830
56110013557	Phycobilisome protein; Region: Phycobilisome; cl08227
56110013558	Predicted hydrocarbon binding protein (contains V4R domain) [General function prediction only]; Region: COG1719
56110013559	V4R domain; Region: V4R; pfam02830
56110013560	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110013561	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110013562	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110013563	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110013564	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110013565	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013566	dimer interface [polypeptide binding]; other site
56110013567	phosphorylation site [posttranslational modification]
56110013568	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013569	ATP binding site [chemical binding]; other site
56110013570	Mg2+ binding site [ion binding]; other site
56110013571	G-X-G motif; other site
56110013572	GAF domain; Region: GAF; pfam01590
56110013573	Phytochrome region; Region: PHY; pfam00360
56110013574	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110013575	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110013576	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013577	dimer interface [polypeptide binding]; other site
56110013578	phosphorylation site [posttranslational modification]
56110013579	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013580	ATP binding site [chemical binding]; other site
56110013581	Mg2+ binding site [ion binding]; other site
56110013582	G-X-G motif; other site
56110013583	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
56110013584	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
56110013585	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110013586	hydroxyglutarate oxidase; Provisional; Region: PRK11728
56110013587	ribosome recycling factor; Reviewed; Region: frr; PRK00083
56110013588	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
56110013589	hinge region; other site
56110013590	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
56110013591	putative nucleotide binding site [chemical binding]; other site
56110013592	uridine monophosphate binding site [chemical binding]; other site
56110013593	homohexameric interface [polypeptide binding]; other site
56110013594	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
56110013595	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110013596	putative catalytic residue [active]
56110013597	hydrolase, alpha/beta fold family protein; Region: PLN02824
56110013598	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
56110013599	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
56110013600	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
56110013601	Sulfate transporter family; Region: Sulfate_transp; pfam00916
56110013602	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
56110013603	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
56110013604	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110013605	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110013606	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110013607	putative active site [active]
56110013608	putative NTP binding site [chemical binding]; other site
56110013609	putative nucleic acid binding site [nucleotide binding]; other site
56110013610	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110013611	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110013612	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110013613	active site
56110013614	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
56110013615	Glucose inhibited division protein A; Region: GIDA; pfam01134
56110013616	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_2; cd06160
56110013617	Peptidase family M50; Region: Peptidase_M50; pfam02163
56110013618	active site
56110013619	putative substrate binding region [chemical binding]; other site
56110013620	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
56110013621	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110013622	S-adenosylmethionine binding site [chemical binding]; other site
56110013623	AAA ATPase domain; Region: AAA_16; pfam13191
56110013624	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110013625	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110013626	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110013627	structural tetrad; other site
56110013628	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110013629	structural tetrad; other site
56110013630	hypothetical protein; Provisional; Region: PRK11770
56110013631	Domain of unknown function (DUF307); Region: DUF307; pfam03733
56110013632	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
56110013633	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
56110013634	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
56110013635	CHAT domain; Region: CHAT; pfam12770
56110013636	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013637	TPR motif; other site
56110013638	binding surface
56110013639	TPR repeat; Region: TPR_11; pfam13414
56110013640	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
56110013641	active site
56110013642	catalytic triad [active]
56110013643	RDD family; Region: RDD; pfam06271
56110013644	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
56110013645	ABC exporter ATP-binding subunit, DevA family; Region: heterocyst_DevA; TIGR02982
56110013646	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
56110013647	Walker A/P-loop; other site
56110013648	ATP binding site [chemical binding]; other site
56110013649	Q-loop/lid; other site
56110013650	ABC transporter signature motif; other site
56110013651	Walker B; other site
56110013652	D-loop; other site
56110013653	H-loop/switch region; other site
56110013654	DevC protein; Region: devC; TIGR01185
56110013655	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
56110013656	FtsX-like permease family; Region: FtsX; pfam02687
56110013657	ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971
56110013658	ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971
56110013659	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110013660	acetylornithine aminotransferase; Provisional; Region: PRK02627
56110013661	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
56110013662	inhibitor-cofactor binding pocket; inhibition site
56110013663	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110013664	catalytic residue [active]
56110013665	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
56110013666	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
56110013667	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
56110013668	TrkA-N domain; Region: TrkA_N; pfam02254
56110013669	TrkA-C domain; Region: TrkA_C; pfam02080
56110013670	Ion channel; Region: Ion_trans_2; pfam07885
56110013671	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
56110013672	TrkA-N domain; Region: TrkA_N; pfam02254
56110013673	TrkA-C domain; Region: TrkA_C; pfam02080
56110013674	TPR repeat; Region: TPR_11; pfam13414
56110013675	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013676	binding surface
56110013677	TPR repeat; Region: TPR_11; pfam13414
56110013678	TPR motif; other site
56110013679	TPR repeat; Region: TPR_11; pfam13414
56110013680	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013681	binding surface
56110013682	TPR motif; other site
56110013683	TPR repeat; Region: TPR_11; pfam13414
56110013684	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013685	binding surface
56110013686	TPR motif; other site
56110013687	Domain of unknown function (DUF1818); Region: DUF1818; pfam08848
56110013688	DNA-directed RNA polymerase subunit omega; Provisional; Region: ycf61; CHL00191
56110013689	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_3; cd01835
56110013690	active site
56110013691	catalytic triad [active]
56110013692	oxyanion hole [active]
56110013693	Transcriptional regulator [Transcription]; Region: LytR; COG1316
56110013694	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
56110013695	PAS fold; Region: PAS_3; pfam08447
56110013696	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013697	heme pocket [chemical binding]; other site
56110013698	putative active site [active]
56110013699	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110013700	GAF domain; Region: GAF; pfam01590
56110013701	PAS fold; Region: PAS_3; pfam08447
56110013702	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013703	putative active site [active]
56110013704	heme pocket [chemical binding]; other site
56110013705	PAS fold; Region: PAS_4; pfam08448
56110013706	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013707	putative active site [active]
56110013708	PAS fold; Region: PAS; pfam00989
56110013709	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013710	putative active site [active]
56110013711	heme pocket [chemical binding]; other site
56110013712	PAS domain S-box; Region: sensory_box; TIGR00229
56110013713	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013714	putative active site [active]
56110013715	heme pocket [chemical binding]; other site
56110013716	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110013717	PAS domain; Region: PAS; smart00091
56110013718	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110013719	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110013720	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013721	putative active site [active]
56110013722	heme pocket [chemical binding]; other site
56110013723	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013724	dimer interface [polypeptide binding]; other site
56110013725	phosphorylation site [posttranslational modification]
56110013726	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013727	ATP binding site [chemical binding]; other site
56110013728	Mg2+ binding site [ion binding]; other site
56110013729	G-X-G motif; other site
56110013730	Response regulator receiver domain; Region: Response_reg; pfam00072
56110013731	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110013732	active site
56110013733	phosphorylation site [posttranslational modification]
56110013734	intermolecular recognition site; other site
56110013735	dimerization interface [polypeptide binding]; other site
56110013736	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
56110013737	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
56110013738	Substrate binding site; other site
56110013739	Cupin domain; Region: Cupin_2; cl17218
56110013740	Cupin domain; Region: Cupin_2; cl17218
56110013741	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
56110013742	ABC1 family; Region: ABC1; pfam03109
56110013743	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
56110013744	active site
56110013745	ATP binding site [chemical binding]; other site
56110013746	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
56110013747	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013748	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013749	binding surface
56110013750	TPR motif; other site
56110013751	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013752	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013753	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013754	binding surface
56110013755	TPR motif; other site
56110013756	CHAT domain; Region: CHAT; pfam12770
56110013757	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110013758	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
56110013759	lipoyl attachment site [posttranslational modification]; other site
56110013760	glycine dehydrogenase; Provisional; Region: PRK05367
56110013761	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
56110013762	tetramer interface [polypeptide binding]; other site
56110013763	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110013764	catalytic residue [active]
56110013765	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
56110013766	tetramer interface [polypeptide binding]; other site
56110013767	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110013768	catalytic residue [active]
56110013769	Procyclic acidic repetitive protein (PARP); Region: Trypan_PARP; pfam05887
56110013770	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110013771	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110013772	active site
56110013773	ATP binding site [chemical binding]; other site
56110013774	substrate binding site [chemical binding]; other site
56110013775	activation loop (A-loop); other site
56110013776	GUN4-like; Region: GUN4; pfam05419
56110013777	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110013778	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110013779	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110013780	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
56110013781	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
56110013782	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
56110013783	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110013784	catalytic loop [active]
56110013785	iron binding site [ion binding]; other site
56110013786	Sporulation protein and related proteins [Cell division and chromosome partitioning]; Region: SpoIID; COG2385
56110013787	Stage II sporulation protein; Region: SpoIID; pfam08486
56110013788	ParB-like nuclease domain; Region: ParBc; cl02129
56110013789	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
56110013790	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
56110013791	dimerization interface [polypeptide binding]; other site
56110013792	DPS ferroxidase diiron center [ion binding]; other site
56110013793	ion pore; other site
56110013794	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
56110013795	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cl03075
56110013796	dimer interface [polypeptide binding]; other site
56110013797	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
56110013798	Protein of unknown function (DUF1350); Region: DUF1350; pfam07082
56110013799	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110013800	putative active site [active]
56110013801	AAA ATPase domain; Region: AAA_16; pfam13191
56110013802	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013803	TPR motif; other site
56110013804	binding surface
56110013805	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013806	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013807	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013808	binding surface
56110013809	TPR motif; other site
56110013810	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013811	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013812	binding surface
56110013813	TPR motif; other site
56110013814	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013815	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013816	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013817	binding surface
56110013818	TPR motif; other site
56110013819	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013820	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013821	binding surface
56110013822	TPR motif; other site
56110013823	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013824	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110013825	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110013826	binding surface
56110013827	TPR motif; other site
56110013828	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
56110013829	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
56110013830	quinone interaction residues [chemical binding]; other site
56110013831	active site
56110013832	catalytic residues [active]
56110013833	FMN binding site [chemical binding]; other site
56110013834	substrate binding site [chemical binding]; other site
56110013835	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12902
56110013836	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
56110013837	Dihaem cytochrome c; Region: DHC; pfam09626
56110013838	MoxR-like ATPases [General function prediction only]; Region: COG0714
56110013839	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110013840	Walker A motif; other site
56110013841	ATP binding site [chemical binding]; other site
56110013842	Walker B motif; other site
56110013843	arginine finger; other site
56110013844	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
56110013845	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
56110013846	active site
56110013847	Riboflavin kinase; Region: Flavokinase; smart00904
56110013848	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
56110013849	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
56110013850	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
56110013851	Cl- selectivity filter; other site
56110013852	Cl- binding residues [ion binding]; other site
56110013853	pore gating glutamate residue; other site
56110013854	dimer interface [polypeptide binding]; other site
56110013855	FOG: CBS domain [General function prediction only]; Region: COG0517
56110013856	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in bacteria and archaea. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; Region: CBS_pair_EriC_assoc_bac_arch; cd04593
56110013857	AbrB-like transcriptional regulator; Region: AbrB-like; pfam14250
56110013858	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110013859	Probable transposase; Region: OrfB_IS605; pfam01385
56110013860	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110013861	Rrf2 family protein; Region: rrf2_super; TIGR00738
56110013862	Transcriptional regulator; Region: Rrf2; pfam02082
56110013863	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
56110013864	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
56110013865	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110013866	active site
56110013867	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
56110013868	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
56110013869	homotetramer interface [polypeptide binding]; other site
56110013870	FMN binding site [chemical binding]; other site
56110013871	homodimer contacts [polypeptide binding]; other site
56110013872	putative active site [active]
56110013873	putative substrate binding site [chemical binding]; other site
56110013874	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110013875	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110013876	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110013877	putative active site [active]
56110013878	putative NTP binding site [chemical binding]; other site
56110013879	putative nucleic acid binding site [nucleotide binding]; other site
56110013880	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110013881	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110013882	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110013883	active site
56110013884	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
56110013885	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
56110013886	tandem repeat interface [polypeptide binding]; other site
56110013887	oligomer interface [polypeptide binding]; other site
56110013888	active site residues [active]
56110013889	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
56110013890	tandem repeat interface [polypeptide binding]; other site
56110013891	oligomer interface [polypeptide binding]; other site
56110013892	active site residues [active]
56110013893	Predicted transcriptional regulator [Transcription]; Region: COG2345
56110013894	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110013895	putative DNA binding site [nucleotide binding]; other site
56110013896	putative Zn2+ binding site [ion binding]; other site
56110013897	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110013898	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110013899	active site
56110013900	KGK domain; Region: KGK; pfam08872
56110013901	KGK domain; Region: KGK; pfam08872
56110013902	Predicted GTPases (dynamin-related) [General function prediction only]; Region: COG0699
56110013903	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110013904	G1 box; other site
56110013905	GTP/Mg2+ binding site [chemical binding]; other site
56110013906	G2 box; other site
56110013907	Switch I region; other site
56110013908	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110013909	G3 box; other site
56110013910	Switch II region; other site
56110013911	G4 box; other site
56110013912	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
56110013913	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
56110013914	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
56110013915	active site
56110013916	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
56110013917	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
56110013918	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
56110013919	catalytic residues [active]
56110013920	Amino acid permease; Region: AA_permease; pfam00324
56110013921	Predicted ferric reductase [Inorganic ion transport and metabolism]; Region: COG4097
56110013922	Ferric reductase like transmembrane component; Region: Ferric_reduct; pfam01794
56110013923	NAD(P) binding domain of  ferredoxin reductase-like proteins catalyze electron transfer between an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) domain, which varies in orientation with respect to the NAD(P)...; Region: FNR_like_3; cd06198
56110013924	FAD binding pocket [chemical binding]; other site
56110013925	FAD binding motif [chemical binding]; other site
56110013926	phosphate binding motif [ion binding]; other site
56110013927	beta-alpha-beta structure motif; other site
56110013928	NAD binding pocket [chemical binding]; other site
56110013929	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110013930	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013931	putative active site [active]
56110013932	heme pocket [chemical binding]; other site
56110013933	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110013934	dimer interface [polypeptide binding]; other site
56110013935	phosphorylation site [posttranslational modification]
56110013936	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110013937	ATP binding site [chemical binding]; other site
56110013938	Mg2+ binding site [ion binding]; other site
56110013939	G-X-G motif; other site
56110013940	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
56110013941	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
56110013942	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
56110013943	PAS fold; Region: PAS; pfam00989
56110013944	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013945	putative active site [active]
56110013946	heme pocket [chemical binding]; other site
56110013947	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110013948	PAS domain; Region: PAS_9; pfam13426
56110013949	putative active site [active]
56110013950	heme pocket [chemical binding]; other site
56110013951	Protein of unknown function (DUF3148); Region: DUF3148; pfam11347
56110013952	putative lipid kinase; Reviewed; Region: PRK00861
56110013953	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
56110013954	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
56110013955	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
56110013956	active site
56110013957	(T/H)XGH motif; other site
56110013958	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
56110013959	Predicted membrane protein (DUF2157); Region: DUF2157; cl10480
56110013960	GDYXXLXY protein; Region: GDYXXLXY; cl02066
56110013961	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
56110013962	Protein of unknown function (DUF433); Region: DUF433; pfam04255
56110013963	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4634
56110013964	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
56110013965	DEAD/DEAH box helicase; Region: DEAD; pfam00270
56110013966	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
56110013967	oligomeric interface; other site
56110013968	putative active site [active]
56110013969	homodimer interface [polypeptide binding]; other site
56110013970	AAA ATPase domain; Region: AAA_16; pfam13191
56110013971	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
56110013972	Walker A motif; other site
56110013973	ATP binding site [chemical binding]; other site
56110013974	Walker B motif; other site
56110013975	Nucleopolyhedrovirus P10 protein; Region: NPV_P10; pfam05531
56110013976	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
56110013977	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
56110013978	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110013979	Coenzyme A binding pocket [chemical binding]; other site
56110013980	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
56110013981	active site
56110013982	Domain of unknown function (DUF955); Region: DUF955; pfam06114
56110013983	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
56110013984	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110013985	non-specific DNA binding site [nucleotide binding]; other site
56110013986	salt bridge; other site
56110013987	sequence-specific DNA binding site [nucleotide binding]; other site
56110013988	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
56110013989	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
56110013990	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
56110013991	Transposase domain (DUF772); Region: DUF772; pfam05598
56110013992	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
56110013993	Piwi-like: PIWI domain. Domain found in proteins involved in RNA silencing. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The...; Region: Piwi-like; cl00628
56110013994	5' RNA guide strand anchoring site; other site
56110013995	active site
56110013996	Uncharacterized small protein [Function unknown]; Region: COG2886
56110013997	5-methyltetrahydrofolate--homocysteine methyltransferase; Region: metH; TIGR02082
56110013998	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
56110013999	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
56110014000	substrate binding pocket [chemical binding]; other site
56110014001	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
56110014002	B12 binding site [chemical binding]; other site
56110014003	cobalt ligand [ion binding]; other site
56110014004	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
56110014005	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK08389
56110014006	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK07234
56110014007	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110014008	Na+/H+ antiporter subunit; Region: PhaG_MnhG_YufB; pfam03334
56110014009	hypothetical protein; Provisional; Region: PRK07377
56110014010	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12567
56110014011	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110014012	AAA domain; Region: AAA_23; pfam13476
56110014013	AAA domain; Region: AAA_21; pfam13304
56110014014	Walker A/P-loop; other site
56110014015	ATP binding site [chemical binding]; other site
56110014016	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
56110014017	Walker B; other site
56110014018	D-loop; other site
56110014019	H-loop/switch region; other site
56110014020	Uncharacterized conserved protein [Function unknown]; Region: COG4279
56110014021	SWIM zinc finger; Region: SWIM; pfam04434
56110014022	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
56110014023	SNF2 Helicase protein; Region: DUF3670; pfam12419
56110014024	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110014025	ATP binding site [chemical binding]; other site
56110014026	putative Mg++ binding site [ion binding]; other site
56110014027	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110014028	nucleotide binding region [chemical binding]; other site
56110014029	ATP-binding site [chemical binding]; other site
56110014030	short chain dehydrogenase; Provisional; Region: PRK08303
56110014031	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110014032	NAD(P) binding site [chemical binding]; other site
56110014033	active site
56110014034	hypothetical protein; Provisional; Region: PRK09256
56110014035	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
56110014036	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110014037	Class I aldolases; Region: Aldolase_Class_I; cl17187
56110014038	catalytic residue [active]
56110014039	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
56110014040	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110014041	FeS/SAM binding site; other site
56110014042	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
56110014043	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
56110014044	putative NAD(P) binding site [chemical binding]; other site
56110014045	homodimer interface [polypeptide binding]; other site
56110014046	homotetramer interface [polypeptide binding]; other site
56110014047	active site
56110014048	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
56110014049	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
56110014050	Catalytic site [active]
56110014051	RDD family; Region: RDD; pfam06271
56110014052	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110014053	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014054	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014055	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014056	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014057	Predicted GTPase [General function prediction only]; Region: COG3596
56110014058	YfjP GTPase; Region: YfjP; cd11383
56110014059	G1 box; other site
56110014060	GTP/Mg2+ binding site [chemical binding]; other site
56110014061	Switch I region; other site
56110014062	G2 box; other site
56110014063	Switch II region; other site
56110014064	G3 box; other site
56110014065	G4 box; other site
56110014066	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
56110014067	The Delta12 Fatty Acid Desaturase (Delta12-FADS)-like CD includes the integral-membrane enzymes, delta-12 acyl-lipid desaturases, oleate 12-hydroxylases, omega3 and omega6 fatty acid desaturases, and other related proteins, found in a wide range of...; Region: Delta12-FADS-like; cd03507
56110014068	putative di-iron ligands [ion binding]; other site
56110014069	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
56110014070	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
56110014071	Domain of unknown function (DUF4070); Region: DUF4070; pfam13282
56110014072	Domains in Na-Ca exchangers and integrin-beta4; Region: Calx_beta; smart00237
56110014073	Calx-beta domain; Region: Calx-beta; cl02522
56110014074	Calx-beta domain; Region: Calx-beta; cl02522
56110014075	Calx-beta domain; Region: Calx-beta; pfam03160
56110014076	Calx-beta domain; Region: Calx-beta; cl02522
56110014077	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
56110014078	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
56110014079	HIGH motif; other site
56110014080	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
56110014081	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
56110014082	active site
56110014083	KMSKS motif; other site
56110014084	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
56110014085	tRNA binding surface [nucleotide binding]; other site
56110014086	CRISPR/Cas system-associated protein Csx3; Region: Csx3_III-U; cd09740
56110014087	CRISPR/Cas system-associated protein Csx3; Region: Csx3_III-U; cl09837
56110014088	CRISPR-associated protein, TIGR03985 family; Region: TIGR03985
56110014089	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cl11817
56110014090	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853
56110014091	CRISPR-associated protein (Cas_Cmr3); Region: Cas_Cmr3; pfam09700
56110014092	CRISPR/Cas system-associated RAMP superfamily protein Cmr3; Region: Cmr3_III-B; cl12075
56110014093	CRISPR/Cas system-associated RAMP superfamily protein Cmr4; Region: Cmr4_III-B; cl17440
56110014094	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214
56110014095	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110014096	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110014097	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110014098	CHASE2 domain; Region: CHASE2; pfam05226
56110014099	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110014100	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110014101	dimer interface [polypeptide binding]; other site
56110014102	phosphorylation site [posttranslational modification]
56110014103	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110014104	ATP binding site [chemical binding]; other site
56110014105	Mg2+ binding site [ion binding]; other site
56110014106	G-X-G motif; other site
56110014107	Response regulator receiver domain; Region: Response_reg; pfam00072
56110014108	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110014109	active site
56110014110	phosphorylation site [posttranslational modification]
56110014111	intermolecular recognition site; other site
56110014112	dimerization interface [polypeptide binding]; other site
56110014113	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110014114	cyclase homology domain; Region: CHD; cd07302
56110014115	nucleotidyl binding site; other site
56110014116	metal binding site [ion binding]; metal-binding site
56110014117	dimer interface [polypeptide binding]; other site
56110014118	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110014119	binding surface
56110014120	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110014121	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014122	binding surface
56110014123	TPR motif; other site
56110014124	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110014125	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110014126	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014127	binding surface
56110014128	TPR motif; other site
56110014129	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110014130	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110014131	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110014132	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110014133	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110014134	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110014135	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110014136	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110014137	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110014138	Phosphoketolase [Carbohydrate transport and metabolism]; Region: COG3957
56110014139	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
56110014140	TPP-binding site [chemical binding]; other site
56110014141	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
56110014142	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110014143	putative active site [active]
56110014144	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110014145	putative active site [active]
56110014146	HindIII restriction endonuclease; Region: RE_HindIII; pfam09518
56110014147	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
56110014148	DNA methylase; Region: N6_N4_Mtase; pfam01555
56110014149	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
56110014150	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
56110014151	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110014152	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110014153	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014154	putative active site [active]
56110014155	heme pocket [chemical binding]; other site
56110014156	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014157	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110014158	putative active site [active]
56110014159	heme pocket [chemical binding]; other site
56110014160	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014161	putative active site [active]
56110014162	heme pocket [chemical binding]; other site
56110014163	PAS fold; Region: PAS_4; pfam08448
56110014164	hypothetical protein; Provisional; Region: PRK13560
56110014165	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014166	putative active site [active]
56110014167	heme pocket [chemical binding]; other site
56110014168	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014169	putative active site [active]
56110014170	heme pocket [chemical binding]; other site
56110014171	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014172	putative active site [active]
56110014173	heme pocket [chemical binding]; other site
56110014174	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110014175	dimer interface [polypeptide binding]; other site
56110014176	phosphorylation site [posttranslational modification]
56110014177	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110014178	ATP binding site [chemical binding]; other site
56110014179	Mg2+ binding site [ion binding]; other site
56110014180	G-X-G motif; other site
56110014181	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110014182	Response regulator receiver domain; Region: Response_reg; pfam00072
56110014183	active site
56110014184	phosphorylation site [posttranslational modification]
56110014185	intermolecular recognition site; other site
56110014186	dimerization interface [polypeptide binding]; other site
56110014187	Response regulator receiver domain; Region: Response_reg; pfam00072
56110014188	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110014189	active site
56110014190	phosphorylation site [posttranslational modification]
56110014191	intermolecular recognition site; other site
56110014192	dimerization interface [polypeptide binding]; other site
56110014193	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110014194	GAF domain; Region: GAF_3; pfam13492
56110014195	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110014196	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110014197	metal binding site [ion binding]; metal-binding site
56110014198	active site
56110014199	I-site; other site
56110014200	50S ribosome-binding GTPase; Region: MMR_HSR1; pfam01926
56110014201	G1 box; other site
56110014202	GTP/Mg2+ binding site [chemical binding]; other site
56110014203	G2 box; other site
56110014204	Switch I region; other site
56110014205	G3 box; other site
56110014206	Switch II region; other site
56110014207	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
56110014208	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
56110014209	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
56110014210	DHH family; Region: DHH; pfam01368
56110014211	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110014212	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110014213	active site
56110014214	HAMP domain; Region: HAMP; pfam00672
56110014215	Heme NO binding associated; Region: HNOBA; pfam07701
56110014216	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
56110014217	cyclase homology domain; Region: CHD; cd07302
56110014218	nucleotidyl binding site; other site
56110014219	metal binding site [ion binding]; metal-binding site
56110014220	dimer interface [polypeptide binding]; other site
56110014221	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3322
56110014222	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110014223	dimerization interface [polypeptide binding]; other site
56110014224	PAS domain S-box; Region: sensory_box; TIGR00229
56110014225	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014226	putative active site [active]
56110014227	heme pocket [chemical binding]; other site
56110014228	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110014229	dimer interface [polypeptide binding]; other site
56110014230	phosphorylation site [posttranslational modification]
56110014231	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110014232	ATP binding site [chemical binding]; other site
56110014233	Mg2+ binding site [ion binding]; other site
56110014234	G-X-G motif; other site
56110014235	alanine racemase; Reviewed; Region: alr; PRK00053
56110014236	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
56110014237	active site
56110014238	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
56110014239	dimer interface [polypeptide binding]; other site
56110014240	substrate binding site [chemical binding]; other site
56110014241	catalytic residues [active]
56110014242	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3146
56110014243	Protein of unknown function, DUF482; Region: DUF482; pfam04339
56110014244	RibD C-terminal domain; Region: RibD_C; cl17279
56110014245	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
56110014246	hypothetical protein; Validated; Region: PRK00029
56110014247	Uncharacterized conserved protein [Function unknown]; Region: COG0397
56110014248	CP12 domain; Region: CP12; pfam02672
56110014249	Haemolytic domain; Region: Haemolytic; pfam01809
56110014250	Dolichol kinase [Lipid metabolism]; Region: SEC59; COG0170
56110014251	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
56110014252	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
56110014253	active site
56110014254	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
56110014255	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
56110014256	active site
56110014257	(T/H)XGH motif; other site
56110014258	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
56110014259	nudix motif; other site
56110014260	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
56110014261	NAD synthetase; Provisional; Region: PRK13981
56110014262	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
56110014263	multimer interface [polypeptide binding]; other site
56110014264	active site
56110014265	catalytic triad [active]
56110014266	protein interface 1 [polypeptide binding]; other site
56110014267	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
56110014268	homodimer interface [polypeptide binding]; other site
56110014269	NAD binding pocket [chemical binding]; other site
56110014270	ATP binding pocket [chemical binding]; other site
56110014271	Mg binding site [ion binding]; other site
56110014272	active-site loop [active]
56110014273	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110014274	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014275	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014276	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014277	binding surface
56110014278	TPR repeat; Region: TPR_11; pfam13414
56110014279	TPR motif; other site
56110014280	topology modulation protein; Reviewed; Region: PRK08118
56110014281	AAA domain; Region: AAA_17; pfam13207
56110014282	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
56110014283	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
56110014284	domain interfaces; other site
56110014285	active site
56110014286	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
56110014287	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
56110014288	glycogen synthase; Provisional; Region: glgA; PRK00654
56110014289	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
56110014290	ADP-binding pocket [chemical binding]; other site
56110014291	homodimer interface [polypeptide binding]; other site
56110014292	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
56110014293	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110014294	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110014295	4-hydroxybenzoate polyprenyltransferase; Reviewed; Region: ubiA; PRK12870
56110014296	UbiA prenyltransferase family; Region: UbiA; pfam01040
56110014297	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
56110014298	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
56110014299	HNH endonuclease; Region: HNH_2; pfam13391
56110014300	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
56110014301	Permease; Region: Permease; cl00510
56110014302	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
56110014303	Protein of unknown function (DUF3119); Region: DUF3119; pfam11317
56110014304	Prefoldin subunit; Region: Prefoldin_2; pfam01920
56110014305	Protein of unknown function (DUF3086); Region: DUF3086; pfam11285
56110014306	membrane protein; Provisional; Region: PRK14419
56110014307	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110014308	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110014309	active site
56110014310	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110014311	non-specific DNA binding site [nucleotide binding]; other site
56110014312	salt bridge; other site
56110014313	sequence-specific DNA binding site [nucleotide binding]; other site
56110014314	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110014315	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
56110014316	cofactor binding site; other site
56110014317	DNA binding site [nucleotide binding]
56110014318	substrate interaction site [chemical binding]; other site
56110014319	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
56110014320	pyrroline-5-carboxylate reductase; Region: PLN02688
56110014321	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
56110014322	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
56110014323	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
56110014324	catalytic residue [active]
56110014325	Protein of unknown function (DUF3539); Region: DUF3539; pfam12058
56110014326	anthranilate synthase component I-like protein; Validated; Region: PRK05940
56110014327	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
56110014328	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
56110014329	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
56110014330	GTP-binding protein Der; Reviewed; Region: PRK00093
56110014331	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
56110014332	G1 box; other site
56110014333	GTP/Mg2+ binding site [chemical binding]; other site
56110014334	Switch I region; other site
56110014335	G2 box; other site
56110014336	Switch II region; other site
56110014337	G3 box; other site
56110014338	G4 box; other site
56110014339	G5 box; other site
56110014340	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
56110014341	G1 box; other site
56110014342	GTP/Mg2+ binding site [chemical binding]; other site
56110014343	Switch I region; other site
56110014344	G2 box; other site
56110014345	G3 box; other site
56110014346	Switch II region; other site
56110014347	G4 box; other site
56110014348	G5 box; other site
56110014349	Putative restriction endonuclease; Region: Uma2; pfam05685
56110014350	D1 subunit  of photosystem II (PS II); Region: Photosystem-II_D1; cd09289
56110014351	protein I interface; other site
56110014352	D2 interface; other site
56110014353	protein T interface; other site
56110014354	chlorophyll binding site; other site
56110014355	beta carotene binding site; other site
56110014356	pheophytin binding site; other site
56110014357	manganese-stabilizing polypeptide interface; other site
56110014358	CP43 interface; other site
56110014359	protein L interface; other site
56110014360	oxygen evolving complex binding site; other site
56110014361	bromide binding site; other site
56110014362	quinone binding site; other site
56110014363	Fe binding site [ion binding]; other site
56110014364	core light harvesting interface; other site
56110014365	cytochrome b559 alpha subunit interface; other site
56110014366	cytochrome c-550 interface; other site
56110014367	protein J interface; other site
56110014368	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110014369	Coenzyme A binding pocket [chemical binding]; other site
56110014370	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
56110014371	D1 subunit  of photosystem II (PS II); Region: Photosystem-II_D1; cd09289
56110014372	protein I interface; other site
56110014373	D2 interface; other site
56110014374	protein T interface; other site
56110014375	chlorophyll binding site; other site
56110014376	beta carotene binding site; other site
56110014377	pheophytin binding site; other site
56110014378	manganese-stabilizing polypeptide interface; other site
56110014379	CP43 interface; other site
56110014380	protein L interface; other site
56110014381	oxygen evolving complex binding site; other site
56110014382	bromide binding site; other site
56110014383	quinone binding site; other site
56110014384	Fe binding site [ion binding]; other site
56110014385	core light harvesting interface; other site
56110014386	cytochrome b559 alpha subunit interface; other site
56110014387	cytochrome c-550 interface; other site
56110014388	protein J interface; other site
56110014389	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
56110014390	30S subunit binding site; other site
56110014391	Lipoate-protein ligase B [Coenzyme metabolism]; Region: LipB; COG0321
56110014392	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
56110014393	DevC protein; Region: devC; TIGR01185
56110014394	FtsX-like permease family; Region: FtsX; pfam02687
56110014395	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
56110014396	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
56110014397	Walker A/P-loop; other site
56110014398	ATP binding site [chemical binding]; other site
56110014399	Q-loop/lid; other site
56110014400	ABC transporter signature motif; other site
56110014401	Walker B; other site
56110014402	D-loop; other site
56110014403	H-loop/switch region; other site
56110014404	RNA polymerase sigma factor; Validated; Region: PRK05949
56110014405	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
56110014406	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110014407	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
56110014408	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110014409	DNA binding residues [nucleotide binding]
56110014410	RRXRR protein; Region: RRXRR; pfam14239
56110014411	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
56110014412	PLD-like domain; Region: PLDc_2; pfam13091
56110014413	putative active site [active]
56110014414	catalytic site [active]
56110014415	Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium; Region: PLDc_Nuc_like_unchar1_2; cd09173
56110014416	PLD-like domain; Region: PLDc_2; pfam13091
56110014417	putative active site [active]
56110014418	catalytic site [active]
56110014419	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
56110014420	Helix-hairpin-helix motif; Region: HHH; pfam00633
56110014421	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
56110014422	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
56110014423	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110014424	catalytic residue [active]
56110014425	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
56110014426	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
56110014427	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
56110014428	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2187
56110014429	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
56110014430	AAA domain; Region: AAA_33; pfam13671
56110014431	ATP-binding site [chemical binding]; other site
56110014432	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
56110014433	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
56110014434	substrate binding site [chemical binding]; other site
56110014435	ATP binding site [chemical binding]; other site
56110014436	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
56110014437	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
56110014438	5S rRNA interface [nucleotide binding]; other site
56110014439	CTC domain interface [polypeptide binding]; other site
56110014440	L16 interface [polypeptide binding]; other site
56110014441	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
56110014442	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
56110014443	GDP-binding site [chemical binding]; other site
56110014444	ACT binding site; other site
56110014445	IMP binding site; other site
56110014446	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
56110014447	Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic organisms and catalyze  the zinc dependent irreversible deamination of adenosine nucleosides to inosine nucleosides and ammonia. The eukaryotic AMP deaminase...; Region: ADA_AMPD; cd00443
56110014448	active site
56110014449	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
56110014450	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
56110014451	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
56110014452	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110014453	dimerization interface [polypeptide binding]; other site
56110014454	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014455	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110014456	putative active site [active]
56110014457	heme pocket [chemical binding]; other site
56110014458	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014459	putative active site [active]
56110014460	heme pocket [chemical binding]; other site
56110014461	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110014462	PAS fold; Region: PAS_3; pfam08447
56110014463	putative active site [active]
56110014464	heme pocket [chemical binding]; other site
56110014465	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110014466	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110014467	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110014468	dimer interface [polypeptide binding]; other site
56110014469	phosphorylation site [posttranslational modification]
56110014470	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110014471	ATP binding site [chemical binding]; other site
56110014472	Mg2+ binding site [ion binding]; other site
56110014473	G-X-G motif; other site
56110014474	Uncharacterized conserved protein [Function unknown]; Region: COG1434
56110014475	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
56110014476	putative active site [active]
56110014477	Ferredoxin thioredoxin reductase variable alpha chain; Region: FeThRed_A; pfam02941
56110014478	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
56110014479	active site
56110014480	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
56110014481	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
56110014482	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
56110014483	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
56110014484	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
56110014485	metal binding site 2 [ion binding]; metal-binding site
56110014486	putative DNA binding helix; other site
56110014487	metal binding site 1 [ion binding]; metal-binding site
56110014488	dimer interface [polypeptide binding]; other site
56110014489	structural Zn2+ binding site [ion binding]; other site
56110014490	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
56110014491	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
56110014492	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
56110014493	putative active site [active]
56110014494	catalytic triad [active]
56110014495	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
56110014496	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014497	TPR motif; other site
56110014498	binding surface
56110014499	TPR repeat; Region: TPR_11; pfam13414
56110014500	TPR repeat; Region: TPR_11; pfam13414
56110014501	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014502	binding surface
56110014503	TPR motif; other site
56110014504	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110014505	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014506	binding surface
56110014507	TPR motif; other site
56110014508	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110014509	Domain of unknown function (DUF4041); Region: DUF4041; pfam13250
56110014510	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
56110014511	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
56110014512	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
56110014513	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110014514	putative substrate translocation pore; other site
56110014515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110014516	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
56110014517	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
56110014518	catalytic triad [active]
56110014519	Domain of unknown function (DUF4336); Region: DUF4336; pfam14234
56110014520	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
56110014521	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
56110014522	C-terminal domain interface [polypeptide binding]; other site
56110014523	GSH binding site (G-site) [chemical binding]; other site
56110014524	dimer interface [polypeptide binding]; other site
56110014525	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
56110014526	N-terminal domain interface [polypeptide binding]; other site
56110014527	HAS barrel domain; Region: HAS-barrel; pfam09378
56110014528	HerA helicase [Replication, recombination, and repair]; Region: COG0433
56110014529	Domain of unknown function DUF87; Region: DUF87; pfam01935
56110014530	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
56110014531	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
56110014532	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
56110014533	homodimer interface [polypeptide binding]; other site
56110014534	Walker A motif; other site
56110014535	ATP binding site [chemical binding]; other site
56110014536	hydroxycobalamin binding site [chemical binding]; other site
56110014537	Walker B motif; other site
56110014538	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
56110014539	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
56110014540	dimer interface [polypeptide binding]; other site
56110014541	putative functional site; other site
56110014542	putative MPT binding site; other site
56110014543	Uncharacterized protein family UPF0054; Region: UPF0054; cl00402
56110014544	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
56110014545	Domain of unknown function (DUF4330); Region: DUF4330; pfam14221
56110014546	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
56110014547	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
56110014548	iron-sulfur cluster [ion binding]; other site
56110014549	[2Fe-2S] cluster binding site [ion binding]; other site
56110014550	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
56110014551	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
56110014552	Nucleoside recognition; Region: Gate; pfam07670
56110014553	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
56110014554	Domain of unknown function (DUF1995); Region: DUF1995; pfam09353
56110014555	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
56110014556	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110014557	active site
56110014558	metal binding site [ion binding]; metal-binding site
56110014559	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110014560	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110014561	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
56110014562	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110014563	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
56110014564	active site
56110014565	putative substrate binding region [chemical binding]; other site
56110014566	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
56110014567	Peptidase family M48; Region: Peptidase_M48; pfam01435
56110014568	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
56110014569	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
56110014570	dimerization interface [polypeptide binding]; other site
56110014571	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110014572	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110014573	active site
56110014574	phosphorylation site [posttranslational modification]
56110014575	intermolecular recognition site; other site
56110014576	dimerization interface [polypeptide binding]; other site
56110014577	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
56110014578	DNA binding site [nucleotide binding]
56110014579	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
56110014580	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110014581	dimer interface [polypeptide binding]; other site
56110014582	phosphorylation site [posttranslational modification]
56110014583	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110014584	ATP binding site [chemical binding]; other site
56110014585	Mg2+ binding site [ion binding]; other site
56110014586	G-X-G motif; other site
56110014587	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
56110014588	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
56110014589	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
56110014590	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
56110014591	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110014592	Domain of unknown function (DUF4263); Region: DUF4263; pfam14082
56110014593	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
56110014594	Protein export membrane protein; Region: SecD_SecF; cl14618
56110014595	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
56110014596	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
56110014597	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014598	binding surface
56110014599	TPR motif; other site
56110014600	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110014601	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014602	binding surface
56110014603	TPR motif; other site
56110014604	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014605	binding surface
56110014606	TPR motif; other site
56110014607	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
56110014608	Predicted membrane protein [Function unknown]; Region: COG2149
56110014609	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
56110014610	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
56110014611	Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3670
56110014612	Retinal pigment epithelial membrane protein; Region: RPE65; pfam03055
56110014613	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
56110014614	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
56110014615	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110014616	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110014617	Probable transposase; Region: OrfB_IS605; pfam01385
56110014618	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110014619	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110014620	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
56110014621	DXD motif; other site
56110014622	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
56110014623	RNA/DNA hybrid binding site [nucleotide binding]; other site
56110014624	active site
56110014625	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110014626	Walker A motif; other site
56110014627	ATP binding site [chemical binding]; other site
56110014628	Walker B motif; other site
56110014629	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110014630	protein-splicing catalytic site; other site
56110014631	thioester formation/cholesterol transfer; other site
56110014632	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
56110014633	Intein/homing endonuclease [DNA replication, recombination, and repair]; Region: COG1372
56110014634	protein-splicing catalytic site; other site
56110014635	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14948
56110014636	DNA polymerase III subunit delta'; Validated; Region: PRK08485
56110014637	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
56110014638	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014639	binding surface
56110014640	TPR repeat; Region: TPR_11; pfam13414
56110014641	TPR motif; other site
56110014642	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014643	TPR motif; other site
56110014644	TPR repeat; Region: TPR_11; pfam13414
56110014645	binding surface
56110014646	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014647	binding surface
56110014648	TPR motif; other site
56110014649	TPR repeat; Region: TPR_11; pfam13414
56110014650	Predicted transcriptional regulators [Transcription]; Region: COG1695
56110014651	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
56110014652	Protein of unknown function (DUF3611); Region: DUF3611; pfam12263
56110014653	Helix-turn-helix domain; Region: HTH_25; pfam13413
56110014654	Protein of unknown function (DUF3727); Region: DUF3727; pfam12527
56110014655	YceG-like family; Region: YceG; pfam02618
56110014656	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
56110014657	dimerization interface [polypeptide binding]; other site
56110014658	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
56110014659	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110014660	active site
56110014661	motif I; other site
56110014662	motif II; other site
56110014663	gamma-glutamyl kinase; Provisional; Region: PRK05429
56110014664	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
56110014665	nucleotide binding site [chemical binding]; other site
56110014666	homotetrameric interface [polypeptide binding]; other site
56110014667	putative phosphate binding site [ion binding]; other site
56110014668	putative allosteric binding site; other site
56110014669	PUA domain; Region: PUA; pfam01472
56110014670	Domain of unknown function (DUF4327); Region: DUF4327; pfam14217
56110014671	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
56110014672	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
56110014673	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
56110014674	Protein of unknown function (DUF751); Region: DUF751; pfam05421
56110014675	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
56110014676	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
56110014677	Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain; Region: MPP_ACP5; cd07378
56110014678	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110014679	active site
56110014680	metal binding site [ion binding]; metal-binding site
56110014681	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
56110014682	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
56110014683	putative active site cavity [active]
56110014684	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110014685	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110014686	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110014687	dimer interface [polypeptide binding]; other site
56110014688	phosphorylation site [posttranslational modification]
56110014689	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110014690	ATP binding site [chemical binding]; other site
56110014691	Mg2+ binding site [ion binding]; other site
56110014692	G-X-G motif; other site
56110014693	Response regulator receiver domain; Region: Response_reg; pfam00072
56110014694	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110014695	active site
56110014696	phosphorylation site [posttranslational modification]
56110014697	intermolecular recognition site; other site
56110014698	dimerization interface [polypeptide binding]; other site
56110014699	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989
56110014700	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
56110014701	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989
56110014702	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
56110014703	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110014704	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110014705	AAA domain; Region: AAA_21; pfam13304
56110014706	Walker A/P-loop; other site
56110014707	Walker A/P-loop; other site
56110014708	ATP binding site [chemical binding]; other site
56110014709	ATP binding site [chemical binding]; other site
56110014710	Uncharacterized conserved protein [Function unknown]; Region: COG4278
56110014711	TIGR04222 domain; Region: near_uncomplex
56110014712	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
56110014713	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
56110014714	putative substrate binding site [chemical binding]; other site
56110014715	putative ATP binding site [chemical binding]; other site
56110014716	Domain of unknown function (DUF4168); Region: DUF4168; pfam13767
56110014717	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110014718	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110014719	DNA binding residues [nucleotide binding]
56110014720	dimerization interface [polypeptide binding]; other site
56110014721	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
56110014722	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
56110014723	dimer interface [polypeptide binding]; other site
56110014724	motif 1; other site
56110014725	active site
56110014726	motif 2; other site
56110014727	motif 3; other site
56110014728	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
56110014729	anticodon binding site; other site
56110014730	Nitric oxide reductase large subunit [Inorganic ion transport and metabolism]; Region: NorB; COG3256
56110014731	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
56110014732	L11 interface [polypeptide binding]; other site
56110014733	putative EF-Tu interaction site [polypeptide binding]; other site
56110014734	putative EF-G interaction site [polypeptide binding]; other site
56110014735	imidazoleglycerol-phosphate dehydratase; Region: PLN02800
56110014736	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
56110014737	putative active site pocket [active]
56110014738	4-fold oligomerization interface [polypeptide binding]; other site
56110014739	metal binding residues [ion binding]; metal-binding site
56110014740	3-fold/trimer interface [polypeptide binding]; other site
56110014741	enoyl-(acyl carrier protein) reductase; Validated; Region: PRK07370
56110014742	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
56110014743	NAD binding site [chemical binding]; other site
56110014744	homotetramer interface [polypeptide binding]; other site
56110014745	homodimer interface [polypeptide binding]; other site
56110014746	substrate binding site [chemical binding]; other site
56110014747	active site
56110014748	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110014749	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
56110014750	ligand binding site [chemical binding]; other site
56110014751	flexible hinge region; other site
56110014752	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
56110014753	putative switch regulator; other site
56110014754	non-specific DNA interactions [nucleotide binding]; other site
56110014755	DNA binding site [nucleotide binding]
56110014756	sequence specific DNA binding site [nucleotide binding]; other site
56110014757	putative cAMP binding site [chemical binding]; other site
56110014758	Protein of unknown function (DUF3084); Region: DUF3084; pfam11283
56110014759	Uncharacterized protein conserved in bacteria with the myosin-like domain [Function unknown]; Region: COG4372
56110014760	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
56110014761	Protein of unknown function (DUF3146); Region: DUF3146; pfam11344
56110014762	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
56110014763	putative active site [active]
56110014764	catalytic residue [active]
56110014765	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
56110014766	photosystem II reaction center protein H; Provisional; Region: psbH; PRK02624
56110014767	photosystem II reaction center protein N; Provisional; Region: psbN; PRK13183
56110014768	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110014769	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110014770	active site
56110014771	short chain dehydrogenase; Provisional; Region: PRK08303
56110014772	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110014773	NAD(P) binding site [chemical binding]; other site
56110014774	active site
56110014775	TPR repeat; Region: TPR_11; pfam13414
56110014776	TPR repeat; Region: TPR_11; pfam13414
56110014777	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014778	binding surface
56110014779	TPR motif; other site
56110014780	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014781	binding surface
56110014782	TPR repeat; Region: TPR_11; pfam13414
56110014783	TPR motif; other site
56110014784	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
56110014785	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110014786	binding surface
56110014787	TPR motif; other site
56110014788	HEAT repeats; Region: HEAT_2; pfam13646
56110014789	HEAT repeats; Region: HEAT_2; pfam13646
56110014790	argininosuccinate lyase; Provisional; Region: PRK00855
56110014791	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
56110014792	active sites [active]
56110014793	tetramer interface [polypeptide binding]; other site
56110014794	GAF domain; Region: GAF_3; pfam13492
56110014795	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110014796	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110014797	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
56110014798	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
56110014799	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
56110014800	P loop; other site
56110014801	GTP binding site [chemical binding]; other site
56110014802	transcription antitermination protein NusB; Provisional; Region: nusB; PRK09634
56110014803	putative RNA binding site [nucleotide binding]; other site
56110014804	Uncharacterized conserved protein [Function unknown]; Region: COG2928
56110014805	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
56110014806	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110014807	putative metal binding site; other site
56110014808	transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282
56110014809	GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Region: GT_2_like_a; cd02522
56110014810	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
56110014811	Probable Catalytic site; other site
56110014812	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
56110014813	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
56110014814	putative active site [active]
56110014815	RRXRR protein; Region: RRXRR; pfam14239
56110014816	Double zinc ribbon; Region: DZR; pfam12773
56110014817	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
56110014818	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
56110014819	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110014820	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110014821	phosphopeptide binding site; other site
56110014822	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110014823	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110014824	phosphopeptide binding site; other site
56110014825	Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957
56110014826	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110014827	photochlorophyllide reductase subunit B; Region: chlB; CHL00076
56110014828	Pchlide_reductase_B: B protein of the NB protein complex of Protochlorophyllide (Pchlide)_reductase. Pchlide reductase catalyzes the reductive formation of chlorophyllide (chlide) from protochlorophyllide (pchlide) during biosynthesis of chlorophylls and...; Region: Pchlide_reductase_B; cd01981
56110014829	Proto-chlorophyllide reductase 57 kD subunit; Region: PCP_red; pfam08369
56110014830	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
56110014831	5-methylcytosine-specific restriction enzyme subunit McrB; Provisional; Region: PRK11331
56110014832	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110014833	active site
56110014834	NTP binding site [chemical binding]; other site
56110014835	metal binding triad [ion binding]; metal-binding site
56110014836	antibiotic binding site [chemical binding]; other site
56110014837	ribonuclease PH; Reviewed; Region: rph; PRK00173
56110014838	Ribonuclease PH; Region: RNase_PH_bact; cd11362
56110014839	hexamer interface [polypeptide binding]; other site
56110014840	active site
56110014841	adenylate kinase; Reviewed; Region: adk; PRK00279
56110014842	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
56110014843	AMP-binding site [chemical binding]; other site
56110014844	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
56110014845	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
56110014846	cob(I)yrinic acid a,c-diamide adenosyltransferase; Validated; Region: PRK07414
56110014847	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
56110014848	catalytic motif [active]
56110014849	Zn binding site [ion binding]; other site
56110014850	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
56110014851	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
56110014852	trimer interface [polypeptide binding]; other site
56110014853	active site
56110014854	Thymidylate synthase complementing protein; Region: Thy1; cl03630
56110014855	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cl17442
56110014856	protein-splicing catalytic site; other site
56110014857	thioester formation/cholesterol transfer; other site
56110014858	Hint (Hedgehog/Intein) domain C-terminal region; Region: HintC; smart00305
56110014859	Thymidylate synthase complementing protein; Region: Thy1; cl03630
56110014860	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
56110014861	active site
56110014862	dimerization interface [polypeptide binding]; other site
56110014863	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
56110014864	TrkA-N domain; Region: TrkA_N; pfam02254
56110014865	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
56110014866	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
56110014867	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
56110014868	Phosphoenolpyruvate carboxylase; Region: PEPcase; pfam00311
56110014869	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
56110014870	C-3',4' desaturase CrtD; Region: desat_CrtD; TIGR02733
56110014871	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110014872	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110014873	anti sigma factor interaction site; other site
56110014874	regulatory phosphorylation site [posttranslational modification]; other site
56110014875	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
56110014876	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
56110014877	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
56110014878	PEP-CTERM family integral membrane protein; Region: PEP_integral; TIGR02921
56110014879	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
56110014880	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
56110014881	Mg-protoporphyrin IX methyl transferase; Validated; Region: PRK07580
56110014882	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110014883	S-adenosylmethionine binding site [chemical binding]; other site
56110014884	Magnesium-protoporphyrin IX methyltransferase C-terminus; Region: Mg-por_mtran_C; pfam07109
56110014885	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
56110014886	active site
56110014887	dimer interfaces [polypeptide binding]; other site
56110014888	catalytic residues [active]
56110014889	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
56110014890	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
56110014891	active site
56110014892	dimer interface [polypeptide binding]; other site
56110014893	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
56110014894	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
56110014895	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
56110014896	active site
56110014897	catalytic triad [active]
56110014898	oxyanion hole [active]
56110014899	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Provisional; Region: PRK13371
56110014900	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Region: ispH_lytB; TIGR00216
56110014901	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
56110014902	NACHT domain; Region: NACHT; pfam05729
56110014903	Walker A motif; other site
56110014904	ATP binding site [chemical binding]; other site
56110014905	Walker B motif; other site
56110014906	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
56110014907	Mechanosensitive ion channel; Region: MS_channel; pfam00924
56110014908	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110014909	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110014910	S-adenosylmethionine binding site [chemical binding]; other site
56110014911	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14333
56110014912	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
56110014913	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110014914	FeS/SAM binding site; other site
56110014915	TRAM domain; Region: TRAM; pfam01938
56110014916	Domain of unknown function (DUF4365); Region: DUF4365; pfam14280
56110014917	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110014918	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110014919	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110014920	putative active site [active]
56110014921	putative NTP binding site [chemical binding]; other site
56110014922	putative nucleic acid binding site [nucleotide binding]; other site
56110014923	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110014924	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110014925	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110014926	active site
56110014927	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
56110014928	active site
56110014929	ATP binding site [chemical binding]; other site
56110014930	Phosphotransferase enzyme family; Region: APH; pfam01636
56110014931	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110014932	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110014933	structural tetrad; other site
56110014934	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
56110014935	Beta-lactamase superfamily domain; Region: Lactamase_B_3; pfam13483
56110014936	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
56110014937	putative active site pocket [active]
56110014938	dimerization interface [polypeptide binding]; other site
56110014939	putative catalytic residue [active]
56110014940	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
56110014941	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
56110014942	active site
56110014943	catalytic residues [active]
56110014944	ergothioneine biosynthesis protein EgtC; Region: TIGR03442
56110014945	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
56110014946	putative active site [active]
56110014947	putative dimer interface [polypeptide binding]; other site
56110014948	ergothioneine biosynthesis protein EgtB; Region: egtB_TIGR03440
56110014949	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
56110014950	dimethylhistidine N-methyltransferase; Region: egtD_ergothio; TIGR03438
56110014951	Uncharacterized conserved protein (DUF2260); Region: DUF2260; pfam10017
56110014952	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; cl00614
56110014953	ABC-2 type transporter; Region: ABC2_membrane; cl17235
56110014954	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
56110014955	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
56110014956	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110014957	Walker A/P-loop; other site
56110014958	ATP binding site [chemical binding]; other site
56110014959	Q-loop/lid; other site
56110014960	ABC transporter signature motif; other site
56110014961	Walker B; other site
56110014962	D-loop; other site
56110014963	H-loop/switch region; other site
56110014964	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110014965	putative active site [active]
56110014966	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
56110014967	UbiA prenyltransferase family; Region: UbiA; pfam01040
56110014968	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
56110014969	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
56110014970	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
56110014971	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
56110014972	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
56110014973	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
56110014974	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
56110014975	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386
56110014976	Subunit I/III interface [polypeptide binding]; other site
56110014977	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110014978	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
56110014979	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
56110014980	dimer interface [polypeptide binding]; other site
56110014981	putative CheW interface [polypeptide binding]; other site
56110014982	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110014983	HSP70 interaction site [polypeptide binding]; other site
56110014984	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014985	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110014986	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014987	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110014988	Ycf66 protein N-terminus; Region: Ycf66_N; pfam07444
56110014989	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
56110014990	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
56110014991	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
56110014992	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
56110014993	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
56110014994	maltose O-acetyltransferase; Provisional; Region: PRK10092
56110014995	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
56110014996	active site
56110014997	substrate binding site [chemical binding]; other site
56110014998	trimer interface [polypeptide binding]; other site
56110014999	CoA binding site [chemical binding]; other site
56110015000	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
56110015001	putative active site [active]
56110015002	putative metal binding residues [ion binding]; other site
56110015003	signature motif; other site
56110015004	putative dimer interface [polypeptide binding]; other site
56110015005	putative phosphate binding site [ion binding]; other site
56110015006	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110015007	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110015008	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110015009	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110015010	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110015011	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110015012	structural tetrad; other site
56110015013	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
56110015014	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK02746
56110015015	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
56110015016	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
56110015017	Domain of unknown function (DUF4336); Region: DUF4336; pfam14234
56110015018	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
56110015019	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
56110015020	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
56110015021	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
56110015022	dimer interface [polypeptide binding]; other site
56110015023	catalytic triad [active]
56110015024	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
56110015025	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110015026	non-specific DNA binding site [nucleotide binding]; other site
56110015027	salt bridge; other site
56110015028	sequence-specific DNA binding site [nucleotide binding]; other site
56110015029	Homeodomain-like domain; Region: HTH_23; pfam13384
56110015030	Winged helix-turn helix; Region: HTH_29; pfam13551
56110015031	Homeodomain-like domain; Region: HTH_32; pfam13565
56110015032	Caspase domain; Region: Peptidase_C14; pfam00656
56110015033	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110015034	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110015035	structural tetrad; other site
56110015036	YcxB-like protein; Region: YcxB; pfam14317
56110015037	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
56110015038	active site
56110015039	hydrophilic channel; other site
56110015040	dimerization interface [polypeptide binding]; other site
56110015041	catalytic residues [active]
56110015042	active site lid [active]
56110015043	Protein of unknown function (DUF2488); Region: Ycf54; pfam10674
56110015044	Deoxyxylulose-5-phosphate synthase [Coenzyme metabolism / Lipid metabolism]; Region: Dxs; COG1154
56110015045	Divergent PAP2 family; Region: DUF212; pfam02681
56110015046	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
56110015047	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
56110015048	substrate binding pocket [chemical binding]; other site
56110015049	chain length determination region; other site
56110015050	substrate-Mg2+ binding site; other site
56110015051	catalytic residues [active]
56110015052	aspartate-rich region 1; other site
56110015053	active site lid residues [active]
56110015054	aspartate-rich region 2; other site
56110015055	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14186
56110015056	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
56110015057	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
56110015058	homodimer interface [polypeptide binding]; other site
56110015059	NADP binding site [chemical binding]; other site
56110015060	substrate binding site [chemical binding]; other site
56110015061	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110015062	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
56110015063	cofactor binding site; other site
56110015064	DNA binding site [nucleotide binding]
56110015065	substrate interaction site [chemical binding]; other site
56110015066	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110015067	Proline dehydrogenase; Region: Pro_dh; pfam01619
56110015068	Delta(1)-pyrroline-5-carboxylate dehydrogenase, RocA; Region: ALDH_PutA-P5CDH-RocA; cd07124
56110015069	delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; Region: D1pyr5carbox2; TIGR01237
56110015070	Glutamate binding site [chemical binding]; other site
56110015071	homodimer interface [polypeptide binding]; other site
56110015072	NAD binding site [chemical binding]; other site
56110015073	catalytic residues [active]
56110015074	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
56110015075	Protein of unknown function (DUF3584); Region: DUF3584; pfam12128
56110015076	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110015077	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110015078	phosphopeptide binding site; other site
56110015079	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110015080	Switch II region; other site
56110015081	G4 box; other site
56110015082	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110015083	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110015084	active site
56110015085	ATP binding site [chemical binding]; other site
56110015086	substrate binding site [chemical binding]; other site
56110015087	activation loop (A-loop); other site
56110015088	Protein kinase domain; Region: Pkinase; pfam00069
56110015089	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110015090	active site
56110015091	ATP binding site [chemical binding]; other site
56110015092	substrate binding site [chemical binding]; other site
56110015093	activation loop (A-loop); other site
56110015094	Protein kinase domain; Region: Pkinase; pfam00069
56110015095	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110015096	active site
56110015097	ATP binding site [chemical binding]; other site
56110015098	substrate binding site [chemical binding]; other site
56110015099	activation loop (A-loop); other site
56110015100	Type IV pilin PilA; Region: Pilin_PilA; pfam14245
56110015101	Protein kinase domain; Region: Pkinase; pfam00069
56110015102	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110015103	active site
56110015104	ATP binding site [chemical binding]; other site
56110015105	substrate binding site [chemical binding]; other site
56110015106	activation loop (A-loop); other site
56110015107	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110015108	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
56110015109	phosphopeptide binding site; other site
56110015110	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110015111	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110015112	structural tetrad; other site
56110015113	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
56110015114	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
56110015115	putative phosphate acyltransferase; Provisional; Region: PRK05331
56110015116	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
56110015117	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
56110015118	dimer interface [polypeptide binding]; other site
56110015119	active site
56110015120	CoA binding pocket [chemical binding]; other site
56110015121	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
56110015122	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
56110015123	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
56110015124	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
56110015125	putative acyl-acceptor binding pocket; other site
56110015126	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
56110015127	Uncharacterized conserved protein [Function unknown]; Region: COG1434
56110015128	putative active site [active]
56110015129	LAGLIDADG DNA endonuclease family; Region: LAGLIDADG_2; pfam03161
56110015130	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
56110015131	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110015132	P-loop; other site
56110015133	Magnesium ion binding site [ion binding]; other site
56110015134	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110015135	Magnesium ion binding site [ion binding]; other site
56110015136	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
56110015137	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
56110015138	CRISPR/Cas system-associated protein Csc1; Region: Csc1_I-D; cd09711
56110015139	CRISPR type I-D/CYANO-associated protein Csc1; Region: cas_Csc1; TIGR03159
56110015140	CRISPR/Cas system-associated protein Csc2; Region: Csc2_I-D; cl11869
56110015141	CRISPR/Cas system-associated protein Cas10d; Region: Cas10d_I-D; cd09712
56110015142	CRISPR type I-D/CYANO-associated protein Csc3/Cas10d; Region: cas_Csc3; TIGR03174
56110015143	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
56110015144	CRISPR-associated helicase Cas3, subtype CYANO; Region: cas3_cyano; TIGR03158
56110015145	Transposase domain (DUF772); Region: DUF772; pfam05598
56110015146	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110015147	WYL domain; Region: WYL; pfam13280
56110015148	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
56110015149	homotrimer interaction site [polypeptide binding]; other site
56110015150	zinc binding site [ion binding]; other site
56110015151	CDP-binding sites; other site
56110015152	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
56110015153	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_4; cd08500
56110015154	NCAIR mutase (PurE)-related proteins [General function prediction only]; Region: COG1691
56110015155	AIR carboxylase; Region: AIRC; smart01001
56110015156	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110015157	putative active site [active]
56110015158	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110015159	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110015160	H+ Antiporter protein; Region: 2A0121; TIGR00900
56110015161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110015162	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
56110015163	Recombination protein O N terminal; Region: RecO_N; pfam11967
56110015164	Recombination protein O C terminal; Region: RecO_C; pfam02565
56110015165	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
56110015166	intersubunit interface [polypeptide binding]; other site
56110015167	active site
56110015168	catalytic residue [active]
56110015169	AMIN domain; Region: AMIN; pfam11741
56110015170	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
56110015171	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
56110015172	active site
56110015173	metal binding site [ion binding]; metal-binding site
56110015174	AMIN domain; Region: AMIN; pfam11741
56110015175	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
56110015176	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
56110015177	active site
56110015178	metal binding site [ion binding]; metal-binding site
56110015179	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_23; cd04682
56110015180	nudix motif; other site
56110015181	ChaB; Region: ChaB; cl01887
56110015182	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; pfam10013
56110015183	Taspase1_like domains; Taspase1 catalyzes the cleavage of the mix lineage leukemia (MLL) nuclear protein and transcription factor TFIIA. Taspase1 is a threonine aspartase, a member of the Ntn hydrolase superfamily and the type 2 asparaginase family. A...; Region: Taspase1_like; cd04514
56110015184	active site
56110015185	dimer interface [polypeptide binding]; other site
56110015186	catalytic nucleophile [active]
56110015187	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110015188	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14360
56110015189	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
56110015190	Substrate binding site; other site
56110015191	Mg++ binding site; other site
56110015192	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
56110015193	active site
56110015194	substrate binding site [chemical binding]; other site
56110015195	CoA binding site [chemical binding]; other site
56110015196	Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]; Region: COG3437
56110015197	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015198	active site
56110015199	phosphorylation site [posttranslational modification]
56110015200	intermolecular recognition site; other site
56110015201	dimerization interface [polypeptide binding]; other site
56110015202	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
56110015203	Zn2+ binding site [ion binding]; other site
56110015204	Mg2+ binding site [ion binding]; other site
56110015205	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
56110015206	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110015207	S-adenosylmethionine binding site [chemical binding]; other site
56110015208	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
56110015209	Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism]; Region: COG2971
56110015210	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
56110015211	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
56110015212	Zn binding site [ion binding]; other site
56110015213	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110015214	anti sigma factor interaction site; other site
56110015215	regulatory phosphorylation site [posttranslational modification]; other site
56110015216	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5381
56110015217	Cache domain; Region: Cache_1; pfam02743
56110015218	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
56110015219	dimerization interface [polypeptide binding]; other site
56110015220	PAS domain; Region: PAS_9; pfam13426
56110015221	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110015222	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110015223	Protein of unknown function (DUF561); Region: DUF561; pfam04481
56110015224	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
56110015225	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
56110015226	active site residue [active]
56110015227	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
56110015228	active site residue [active]
56110015229	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
56110015230	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
56110015231	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
56110015232	substrate binding site [chemical binding]; other site
56110015233	ATP binding site [chemical binding]; other site
56110015234	Myo-inositol-1-phosphate synthase [Lipid metabolism]; Region: INO1; COG1260
56110015235	Myo-inositol-1-phosphate synthase; Region: NAD_binding_5; cl00554
56110015236	histidinol-phosphate aminotransferase; Provisional; Region: PRK02610
56110015237	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110015238	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110015239	homodimer interface [polypeptide binding]; other site
56110015240	catalytic residue [active]
56110015241	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110015242	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
56110015243	Coenzyme A binding pocket [chemical binding]; other site
56110015244	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015245	GAF domain; Region: GAF; pfam01590
56110015246	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015247	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110015248	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015249	dimer interface [polypeptide binding]; other site
56110015250	phosphorylation site [posttranslational modification]
56110015251	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015252	ATP binding site [chemical binding]; other site
56110015253	Mg2+ binding site [ion binding]; other site
56110015254	G-X-G motif; other site
56110015255	Response regulator receiver domain; Region: Response_reg; pfam00072
56110015256	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015257	active site
56110015258	phosphorylation site [posttranslational modification]
56110015259	intermolecular recognition site; other site
56110015260	dimerization interface [polypeptide binding]; other site
56110015261	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015262	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110015263	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110015264	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110015265	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015266	dimer interface [polypeptide binding]; other site
56110015267	phosphorylation site [posttranslational modification]
56110015268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015269	ATP binding site [chemical binding]; other site
56110015270	Mg2+ binding site [ion binding]; other site
56110015271	G-X-G motif; other site
56110015272	Response regulator receiver domain; Region: Response_reg; pfam00072
56110015273	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015274	active site
56110015275	phosphorylation site [posttranslational modification]
56110015276	intermolecular recognition site; other site
56110015277	dimerization interface [polypeptide binding]; other site
56110015278	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110015279	cyclase homology domain; Region: CHD; cd07302
56110015280	nucleotidyl binding site; other site
56110015281	metal binding site [ion binding]; metal-binding site
56110015282	dimer interface [polypeptide binding]; other site
56110015283	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
56110015284	Ycf39; Provisional; Region: ycf39; CHL00194
56110015285	NAD(P) binding site [chemical binding]; other site
56110015286	putative active site [active]
56110015287	Putative phosphatase (DUF442); Region: DUF442; cl17385
56110015288	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
56110015289	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
56110015290	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
56110015291	active site residue [active]
56110015292	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
56110015293	active site residue [active]
56110015294	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
56110015295	putative catalytic site [active]
56110015296	putative phosphate binding site [ion binding]; other site
56110015297	active site
56110015298	metal binding site A [ion binding]; metal-binding site
56110015299	DNA binding site [nucleotide binding]
56110015300	putative AP binding site [nucleotide binding]; other site
56110015301	putative metal binding site B [ion binding]; other site
56110015302	acetolactate synthase; Reviewed; Region: PRK08322
56110015303	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
56110015304	PYR/PP interface [polypeptide binding]; other site
56110015305	dimer interface [polypeptide binding]; other site
56110015306	TPP binding site [chemical binding]; other site
56110015307	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
56110015308	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
56110015309	TPP-binding site [chemical binding]; other site
56110015310	dimer interface [polypeptide binding]; other site
56110015311	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
56110015312	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
56110015313	NAD(P) binding site [chemical binding]; other site
56110015314	catalytic residues [active]
56110015315	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
56110015316	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
56110015317	NADP-binding site; other site
56110015318	homotetramer interface [polypeptide binding]; other site
56110015319	substrate binding site [chemical binding]; other site
56110015320	homodimer interface [polypeptide binding]; other site
56110015321	active site
56110015322	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
56110015323	active site
56110015324	catalytic site [active]
56110015325	substrate binding site [chemical binding]; other site
56110015326	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
56110015327	catalytic site [active]
56110015328	putative active site [active]
56110015329	putative substrate binding site [chemical binding]; other site
56110015330	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
56110015331	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
56110015332	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
56110015333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
56110015334	phenylalanyl-tRNA synthetase subunit alpha; Provisional; Region: pheS; PRK04172
56110015335	Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism]; Region: OtsA; COG0380
56110015336	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
56110015337	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110015338	P-loop; other site
56110015339	Magnesium ion binding site [ion binding]; other site
56110015340	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110015341	Magnesium ion binding site [ion binding]; other site
56110015342	AAA domain; Region: AAA_22; pfam13401
56110015343	AAA ATPase domain; Region: AAA_16; pfam13191
56110015344	Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism]; Region: OtsA; COG0380
56110015345	TrkA-N domain; Region: TrkA_N; pfam02254
56110015346	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
56110015347	TrkA-N domain; Region: TrkA_N; pfam02254
56110015348	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
56110015349	Suppression of tumorigenicity 7; Region: ST7; cd11557
56110015350	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
56110015351	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
56110015352	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015353	PAS domain; Region: PAS_9; pfam13426
56110015354	putative active site [active]
56110015355	heme pocket [chemical binding]; other site
56110015356	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015357	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015358	PAS fold; Region: PAS_3; pfam08447
56110015359	putative active site [active]
56110015360	heme pocket [chemical binding]; other site
56110015361	PAS domain S-box; Region: sensory_box; TIGR00229
56110015362	PAS domain S-box; Region: sensory_box; TIGR00229
56110015363	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015364	putative active site [active]
56110015365	heme pocket [chemical binding]; other site
56110015366	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015367	PAS domain; Region: PAS_9; pfam13426
56110015368	putative active site [active]
56110015369	heme pocket [chemical binding]; other site
56110015370	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110015371	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110015372	metal binding site [ion binding]; metal-binding site
56110015373	active site
56110015374	I-site; other site
56110015375	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110015376	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
56110015377	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
56110015378	substrate binding site [chemical binding]; other site
56110015379	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
56110015380	substrate binding site [chemical binding]; other site
56110015381	ligand binding site [chemical binding]; other site
56110015382	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110015383	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110015384	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110015385	Domain of unknown function (DUF1817); Region: DUF1817; pfam08847
56110015386	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
56110015387	metal binding site 2 [ion binding]; metal-binding site
56110015388	putative DNA binding helix; other site
56110015389	metal binding site 1 [ion binding]; metal-binding site
56110015390	dimer interface [polypeptide binding]; other site
56110015391	structural Zn2+ binding site [ion binding]; other site
56110015392	Response regulator receiver domain; Region: Response_reg; pfam00072
56110015393	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015394	active site
56110015395	phosphorylation site [posttranslational modification]
56110015396	intermolecular recognition site; other site
56110015397	dimerization interface [polypeptide binding]; other site
56110015398	Protein of unknown function (DUF3685); Region: DUF3685; pfam12452
56110015399	TPR repeat; Region: TPR_11; pfam13414
56110015400	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015401	binding surface
56110015402	TPR motif; other site
56110015403	TPR repeat; Region: TPR_11; pfam13414
56110015404	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015405	binding surface
56110015406	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110015407	TPR motif; other site
56110015408	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015409	binding surface
56110015410	TPR motif; other site
56110015411	TPR repeat; Region: TPR_11; pfam13414
56110015412	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015413	binding surface
56110015414	TPR motif; other site
56110015415	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110015416	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110015417	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110015418	CHASE2 domain; Region: CHASE2; pfam05226
56110015419	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110015420	cyclase homology domain; Region: CHD; cd07302
56110015421	nucleotidyl binding site; other site
56110015422	metal binding site [ion binding]; metal-binding site
56110015423	dimer interface [polypeptide binding]; other site
56110015424	photosystem II S4 domain protein; Region: PS_II_S4; TIGR03069
56110015425	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
56110015426	RNA binding surface [nucleotide binding]; other site
56110015427	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
56110015428	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110015429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015430	active site
56110015431	phosphorylation site [posttranslational modification]
56110015432	intermolecular recognition site; other site
56110015433	dimerization interface [polypeptide binding]; other site
56110015434	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110015435	DNA binding residues [nucleotide binding]
56110015436	dimerization interface [polypeptide binding]; other site
56110015437	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110015438	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015439	dimer interface [polypeptide binding]; other site
56110015440	phosphorylation site [posttranslational modification]
56110015441	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015442	ATP binding site [chemical binding]; other site
56110015443	Mg2+ binding site [ion binding]; other site
56110015444	G-X-G motif; other site
56110015445	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
56110015446	Transposase domain (DUF772); Region: DUF772; pfam05598
56110015447	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110015448	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
56110015449	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
56110015450	Soluble P-type ATPase [General function prediction only]; Region: COG4087
56110015451	K+-transporting ATPase, c chain; Region: KdpC; cl00944
56110015452	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
56110015453	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
56110015454	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
56110015455	Ligand Binding Site [chemical binding]; other site
56110015456	Transposase IS200 like; Region: Y1_Tnp; cl00848
56110015457	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
56110015458	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
56110015459	ligand binding site [chemical binding]; other site
56110015460	NAD binding site [chemical binding]; other site
56110015461	dimerization interface [polypeptide binding]; other site
56110015462	catalytic site [active]
56110015463	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
56110015464	putative L-serine binding site [chemical binding]; other site
56110015465	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
56110015466	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110015467	S-adenosylmethionine binding site [chemical binding]; other site
56110015468	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
56110015469	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
56110015470	catalytic residues [active]
56110015471	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
56110015472	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110015473	putative NAD(P) binding site [chemical binding]; other site
56110015474	Domain of unknown function (DUF1816); Region: DUF1816; pfam08846
56110015475	Response regulator receiver domain; Region: Response_reg; pfam00072
56110015476	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015477	active site
56110015478	phosphorylation site [posttranslational modification]
56110015479	intermolecular recognition site; other site
56110015480	dimerization interface [polypeptide binding]; other site
56110015481	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015482	PAS domain; Region: PAS_9; pfam13426
56110015483	putative active site [active]
56110015484	heme pocket [chemical binding]; other site
56110015485	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015486	GAF domain; Region: GAF; pfam01590
56110015487	PAS domain S-box; Region: sensory_box; TIGR00229
56110015488	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015489	putative active site [active]
56110015490	heme pocket [chemical binding]; other site
56110015491	PAS domain S-box; Region: sensory_box; TIGR00229
56110015492	PAS domain S-box; Region: sensory_box; TIGR00229
56110015493	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015494	putative active site [active]
56110015495	heme pocket [chemical binding]; other site
56110015496	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015497	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110015498	putative active site [active]
56110015499	heme pocket [chemical binding]; other site
56110015500	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015501	putative active site [active]
56110015502	heme pocket [chemical binding]; other site
56110015503	PAS domain S-box; Region: sensory_box; TIGR00229
56110015504	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015505	putative active site [active]
56110015506	heme pocket [chemical binding]; other site
56110015507	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110015508	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015509	putative active site [active]
56110015510	heme pocket [chemical binding]; other site
56110015511	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015512	dimer interface [polypeptide binding]; other site
56110015513	phosphorylation site [posttranslational modification]
56110015514	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015515	ATP binding site [chemical binding]; other site
56110015516	Mg2+ binding site [ion binding]; other site
56110015517	G-X-G motif; other site
56110015518	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027
56110015519	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
56110015520	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
56110015521	putative dimer interface [polypeptide binding]; other site
56110015522	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110015523	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110015524	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
56110015525	protein binding site [polypeptide binding]; other site
56110015526	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110015527	putative active site [active]
56110015528	Beta-lactamase class D [Defense mechanisms]; Region: COG2602
56110015529	PAS fold; Region: PAS_4; pfam08448
56110015530	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015531	GAF domain; Region: GAF; pfam01590
56110015532	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015533	PAS domain; Region: PAS_9; pfam13426
56110015534	putative active site [active]
56110015535	heme pocket [chemical binding]; other site
56110015536	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110015537	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015538	dimer interface [polypeptide binding]; other site
56110015539	phosphorylation site [posttranslational modification]
56110015540	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015541	ATP binding site [chemical binding]; other site
56110015542	Mg2+ binding site [ion binding]; other site
56110015543	G-X-G motif; other site
56110015544	Protein of unknown function (DUF2949); Region: DUF2949; pfam11165
56110015545	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
56110015546	marine proteobacterial sortase target protein; Region: marine_srt_targ; TIGR03788
56110015547	vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; Region: vWA_interalpha_trypsin_inhibitor; cd01461
56110015548	metal ion-dependent adhesion site (MIDAS); other site
56110015549	Proteobacterial lipase chaperone protein; Region: Lipase_chap; cl02224
56110015550	AAA domain; Region: AAA_31; pfam13614
56110015551	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110015552	P-loop; other site
56110015553	Magnesium ion binding site [ion binding]; other site
56110015554	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110015555	Magnesium ion binding site [ion binding]; other site
56110015556	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110015557	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110015558	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110015559	putative active site [active]
56110015560	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110015561	putative active site [active]
56110015562	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015563	GAF domain; Region: GAF; pfam01590
56110015564	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015565	dimer interface [polypeptide binding]; other site
56110015566	phosphorylation site [posttranslational modification]
56110015567	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015568	ATP binding site [chemical binding]; other site
56110015569	Mg2+ binding site [ion binding]; other site
56110015570	G-X-G motif; other site
56110015571	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015572	active site
56110015573	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110015574	phosphorylation site [posttranslational modification]
56110015575	intermolecular recognition site; other site
56110015576	dimerization interface [polypeptide binding]; other site
56110015577	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015578	dimer interface [polypeptide binding]; other site
56110015579	phosphorylation site [posttranslational modification]
56110015580	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015581	ATP binding site [chemical binding]; other site
56110015582	Mg2+ binding site [ion binding]; other site
56110015583	G-X-G motif; other site
56110015584	GAF domain; Region: GAF_2; pfam13185
56110015585	GAF domain; Region: GAF; pfam01590
56110015586	PAS domain; Region: PAS_8; pfam13188
56110015587	PAS fold; Region: PAS; pfam00989
56110015588	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015589	putative active site [active]
56110015590	heme pocket [chemical binding]; other site
56110015591	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110015592	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015593	active site
56110015594	phosphorylation site [posttranslational modification]
56110015595	intermolecular recognition site; other site
56110015596	dimerization interface [polypeptide binding]; other site
56110015597	Helix-turn-helix domain; Region: HTH_37; pfam13744
56110015598	Helix-turn-helix domain; Region: HTH_37; pfam13744
56110015599	non-specific DNA binding site [nucleotide binding]; other site
56110015600	salt bridge; other site
56110015601	sequence-specific DNA binding site [nucleotide binding]; other site
56110015602	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
56110015603	light-dependent protochlorophyllide reductase; Region: LPOR; TIGR01289
56110015604	light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs; Region: LPOR_like_SDR_c_like; cd09810
56110015605	putative NAD(P) binding site [chemical binding]; other site
56110015606	active site
56110015607	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110015608	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
56110015609	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110015610	linker region; other site
56110015611	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110015612	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015613	binding surface
56110015614	TPR motif; other site
56110015615	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110015616	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110015617	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015618	binding surface
56110015619	TPR motif; other site
56110015620	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015621	binding surface
56110015622	TPR motif; other site
56110015623	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110015624	CHAT domain; Region: CHAT; pfam12770
56110015625	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110015626	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110015627	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110015628	Protein of unknown function (DUF2949); Region: DUF2949; pfam11165
56110015629	GMP synthase; Reviewed; Region: guaA; PRK00074
56110015630	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
56110015631	AMP/PPi binding site [chemical binding]; other site
56110015632	candidate oxyanion hole; other site
56110015633	catalytic triad [active]
56110015634	potential glutamine specificity residues [chemical binding]; other site
56110015635	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
56110015636	ATP Binding subdomain [chemical binding]; other site
56110015637	Ligand Binding sites [chemical binding]; other site
56110015638	Dimerization subdomain; other site
56110015639	Protein of unknown function (DUF3352); Region: DUF3352; pfam11832
56110015640	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
56110015641	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
56110015642	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
56110015643	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases; Region: MORN; smart00698
56110015644	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
56110015645	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
56110015646	MORN repeat; Region: MORN; cl14787
56110015647	MORN repeat; Region: MORN; cl14787
56110015648	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
56110015649	substrate binding site [chemical binding]; other site
56110015650	1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]; Region: GlgB; COG0296
56110015651	N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; Region: E_set_AMPKbeta_like_N; cd02859
56110015652	glycogen binding site [chemical binding]; other site
56110015653	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
56110015654	active site
56110015655	catalytic site [active]
56110015656	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
56110015657	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
56110015658	Putative catalytic domain, repeat 1, of Pseudomonas aeruginosa cardiolipin synthase and similar proteins; Region: PLDc_PaCLS_like_1; cd09155
56110015659	putative active site [active]
56110015660	catalytic site [active]
56110015661	Putative catalytic domain, repeat 2, of Pseudomonas aeruginosa cardiolipin synthase and similar proteins; Region: PLDc_PaCLS_like_2; cd09161
56110015662	putative active site [active]
56110015663	catalytic site [active]
56110015664	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
56110015665	putative catalytic site [active]
56110015666	putative metal binding site [ion binding]; other site
56110015667	putative phosphate binding site [ion binding]; other site
56110015668	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
56110015669	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
56110015670	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110015671	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110015672	structural tetrad; other site
56110015673	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110015674	structural tetrad; other site
56110015675	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110015676	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
56110015677	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
56110015678	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
56110015679	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110015680	primosomal protein N' Region: priA; TIGR00595
56110015681	ATP binding site [chemical binding]; other site
56110015682	putative Mg++ binding site [ion binding]; other site
56110015683	helicase superfamily c-terminal domain; Region: HELICc; smart00490
56110015684	ATP-binding site [chemical binding]; other site
56110015685	GUN4-like; Region: GUN4; pfam05419
56110015686	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
56110015687	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110015688	Coenzyme A binding pocket [chemical binding]; other site
56110015689	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015690	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110015691	putative active site [active]
56110015692	heme pocket [chemical binding]; other site
56110015693	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015694	phosphorylation site [posttranslational modification]
56110015695	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015696	ATP binding site [chemical binding]; other site
56110015697	Mg2+ binding site [ion binding]; other site
56110015698	G-X-G motif; other site
56110015699	Photosystem II protein Y (PsbY); Region: PsbY; pfam06298
56110015700	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
56110015701	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
56110015702	trimer interface [polypeptide binding]; other site
56110015703	putative metal binding site [ion binding]; other site
56110015704	Protein of unknown function (DUF2396); Region: DUF2396; pfam09654
56110015705	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
56110015706	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
56110015707	active site
56110015708	metal binding site [ion binding]; metal-binding site
56110015709	Uncharacterized copper-binding protein [Inorganic ion transport and metabolism]; Region: COG4454
56110015710	methionine aminopeptidase; Provisional; Region: PRK12318
56110015711	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
56110015712	active site
56110015713	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; COG0382
56110015714	UbiA prenyltransferase family; Region: UbiA; pfam01040
56110015715	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
56110015716	Amidase; Region: Amidase; pfam01425
56110015717	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110015718	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110015719	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110015720	ketol-acid reductoisomerase; Provisional; Region: PRK05479
56110015721	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
56110015722	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
56110015723	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
56110015724	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110015725	HSP70 interaction site [polypeptide binding]; other site
56110015726	Protein of unknown function (DUF3143); Region: DUF3143; pfam11341
56110015727	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
56110015728	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
56110015729	catalytic residue [active]
56110015730	putative FPP diphosphate  binding site; other site
56110015731	putative FPP binding hydrophobic cleft; other site
56110015732	dimer interface [polypeptide binding]; other site
56110015733	putative IPP diphosphate binding site; other site
56110015734	Uncharacterized conserved protein [Function unknown]; Region: COG1624
56110015735	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
56110015736	diaminopimelate decarboxylase; Region: lysA; TIGR01048
56110015737	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
56110015738	active site
56110015739	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
56110015740	substrate binding site [chemical binding]; other site
56110015741	catalytic residues [active]
56110015742	dimer interface [polypeptide binding]; other site
56110015743	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
56110015744	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110015745	Coenzyme A binding pocket [chemical binding]; other site
56110015746	Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156
56110015747	active site
56110015748	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
56110015749	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
56110015750	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
56110015751	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
56110015752	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
56110015753	Walker A/P-loop; other site
56110015754	ATP binding site [chemical binding]; other site
56110015755	Q-loop/lid; other site
56110015756	ABC transporter signature motif; other site
56110015757	Walker B; other site
56110015758	D-loop; other site
56110015759	H-loop/switch region; other site
56110015760	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
56110015761	putative carbohydrate binding site [chemical binding]; other site
56110015762	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
56110015763	ABC-2 type transporter; Region: ABC2_membrane; cl17235
56110015764	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110015765	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
56110015766	active site
56110015767	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110015768	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
56110015769	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
56110015770	putative ADP-binding pocket [chemical binding]; other site
56110015771	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110015772	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110015773	active site
56110015774	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110015775	Domain of unknown function (DUF4335); Region: DUF4335; pfam14233
56110015776	Protein of unknown function (DUF3038); Region: DUF3038; pfam11237
56110015777	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
56110015778	MutS domain III; Region: MutS_III; pfam05192
56110015779	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110015780	Walker A/P-loop; other site
56110015781	ATP binding site [chemical binding]; other site
56110015782	Q-loop/lid; other site
56110015783	ABC transporter signature motif; other site
56110015784	Walker B; other site
56110015785	D-loop; other site
56110015786	H-loop/switch region; other site
56110015787	Smr domain; Region: Smr; pfam01713
56110015788	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
56110015789	active site
56110015790	Fe-S cluster binding site [ion binding]; other site
56110015791	PAS domain; Region: PAS_9; pfam13426
56110015792	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015793	PAS fold; Region: PAS_3; pfam08447
56110015794	putative active site [active]
56110015795	heme pocket [chemical binding]; other site
56110015796	PAS domain S-box; Region: sensory_box; TIGR00229
56110015797	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015798	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110015799	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110015800	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015801	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110015802	putative active site [active]
56110015803	heme pocket [chemical binding]; other site
56110015804	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015805	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110015806	putative active site [active]
56110015807	heme pocket [chemical binding]; other site
56110015808	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015809	putative active site [active]
56110015810	heme pocket [chemical binding]; other site
56110015811	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110015812	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015813	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110015814	putative active site [active]
56110015815	heme pocket [chemical binding]; other site
56110015816	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110015817	putative active site [active]
56110015818	heme pocket [chemical binding]; other site
56110015819	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110015820	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015821	dimer interface [polypeptide binding]; other site
56110015822	phosphorylation site [posttranslational modification]
56110015823	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015824	ATP binding site [chemical binding]; other site
56110015825	Mg2+ binding site [ion binding]; other site
56110015826	G-X-G motif; other site
56110015827	Response regulator receiver domain; Region: Response_reg; pfam00072
56110015828	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015829	active site
56110015830	phosphorylation site [posttranslational modification]
56110015831	intermolecular recognition site; other site
56110015832	dimerization interface [polypeptide binding]; other site
56110015833	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110015834	non-specific DNA binding site [nucleotide binding]; other site
56110015835	salt bridge; other site
56110015836	sequence-specific DNA binding site [nucleotide binding]; other site
56110015837	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
56110015838	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
56110015839	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
56110015840	dimer interface [polypeptide binding]; other site
56110015841	[2Fe-2S] cluster binding site [ion binding]; other site
56110015842	tocopherol O-methyltransferase; Region: PLN02244
56110015843	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110015844	S-adenosylmethionine binding site [chemical binding]; other site
56110015845	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110015846	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
56110015847	haemagglutination activity domain; Region: Haemagg_act; pfam05860
56110015848	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4995
56110015849	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110015850	CHASE2 domain; Region: CHASE2; pfam05226
56110015851	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015852	dimer interface [polypeptide binding]; other site
56110015853	phosphorylation site [posttranslational modification]
56110015854	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015855	ATP binding site [chemical binding]; other site
56110015856	Mg2+ binding site [ion binding]; other site
56110015857	G-X-G motif; other site
56110015858	Response regulator receiver domain; Region: Response_reg; pfam00072
56110015859	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015860	active site
56110015861	phosphorylation site [posttranslational modification]
56110015862	intermolecular recognition site; other site
56110015863	dimerization interface [polypeptide binding]; other site
56110015864	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110015865	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110015866	dimer interface [polypeptide binding]; other site
56110015867	phosphorylation site [posttranslational modification]
56110015868	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110015869	ATP binding site [chemical binding]; other site
56110015870	Mg2+ binding site [ion binding]; other site
56110015871	G-X-G motif; other site
56110015872	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110015873	Dynamin family; Region: Dynamin_N; pfam00350
56110015874	G1 box; other site
56110015875	GTP/Mg2+ binding site [chemical binding]; other site
56110015876	G2 box; other site
56110015877	Switch I region; other site
56110015878	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
56110015879	G3 box; other site
56110015880	Switch II region; other site
56110015881	GTP/Mg2+ binding site [chemical binding]; other site
56110015882	G4 box; other site
56110015883	G5 box; other site
56110015884	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
56110015885	Dynamin family; Region: Dynamin_N; pfam00350
56110015886	G1 box; other site
56110015887	GTP/Mg2+ binding site [chemical binding]; other site
56110015888	G2 box; other site
56110015889	Switch I region; other site
56110015890	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
56110015891	G3 box; other site
56110015892	Switch II region; other site
56110015893	GTP/Mg2+ binding site [chemical binding]; other site
56110015894	G4 box; other site
56110015895	G5 box; other site
56110015896	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
56110015897	putative active site [active]
56110015898	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
56110015899	Dynamin family; Region: Dynamin_N; pfam00350
56110015900	G1 box; other site
56110015901	GTP/Mg2+ binding site [chemical binding]; other site
56110015902	G2 box; other site
56110015903	Switch I region; other site
56110015904	G3 box; other site
56110015905	Switch II region; other site
56110015906	G4 box; other site
56110015907	G5 box; other site
56110015908	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110015909	HSP70 interaction site [polypeptide binding]; other site
56110015910	C factor cell-cell signaling protein; Provisional; Region: PRK09009
56110015911	carbonyl reductase sniffer-like, classical (c) SDRs; Region: carb_red_sniffer_like_SDR_c; cd05325
56110015912	NADP binding site [chemical binding]; other site
56110015913	homodimer interface [polypeptide binding]; other site
56110015914	active site
56110015915	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
56110015916	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
56110015917	Mg++ binding site [ion binding]; other site
56110015918	putative catalytic motif [active]
56110015919	substrate binding site [chemical binding]; other site
56110015920	competence damage-inducible protein A; Provisional; Region: PRK00549
56110015921	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
56110015922	putative MPT binding site; other site
56110015923	Competence-damaged protein; Region: CinA; pfam02464
56110015924	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
56110015925	Dehydroquinase class II; Region: DHquinase_II; pfam01220
56110015926	trimer interface [polypeptide binding]; other site
56110015927	active site
56110015928	dimer interface [polypeptide binding]; other site
56110015929	NAD(P)H-quinone oxidoreductase subunit 4; Provisional; Region: PRK12561
56110015930	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
56110015931	HEAT repeats; Region: HEAT_2; pfam13646
56110015932	NACHT domain; Region: NACHT; pfam05729
56110015933	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110015934	Walker A motif; other site
56110015935	ATP binding site [chemical binding]; other site
56110015936	Walker B motif; other site
56110015937	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
56110015938	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015939	binding surface
56110015940	TPR motif; other site
56110015941	TPR repeat; Region: TPR_11; pfam13414
56110015942	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110015943	binding surface
56110015944	TPR motif; other site
56110015945	TPR repeat; Region: TPR_11; pfam13414
56110015946	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110015947	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110015948	active site
56110015949	phosphorylation site [posttranslational modification]
56110015950	intermolecular recognition site; other site
56110015951	dimerization interface [polypeptide binding]; other site
56110015952	DNA gyrase subunit A; Validated; Region: PRK05560
56110015953	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
56110015954	CAP-like domain; other site
56110015955	active site
56110015956	primary dimer interface [polypeptide binding]; other site
56110015957	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110015958	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110015959	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
56110015960	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
56110015961	MoaE interaction surface [polypeptide binding]; other site
56110015962	MoeB interaction surface [polypeptide binding]; other site
56110015963	thiocarboxylated glycine; other site
56110015964	threonine synthase; Validated; Region: PRK07591
56110015965	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
56110015966	homodimer interface [polypeptide binding]; other site
56110015967	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110015968	catalytic residue [active]
56110015969	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
56110015970	MoaE interaction surface [polypeptide binding]; other site
56110015971	MoeB interaction surface [polypeptide binding]; other site
56110015972	thiocarboxylated glycine; other site
56110015973	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
56110015974	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
56110015975	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110015976	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110015977	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110015978	active site
56110015979	ATP binding site [chemical binding]; other site
56110015980	substrate binding site [chemical binding]; other site
56110015981	activation loop (A-loop); other site
56110015982	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
56110015983	von Willebrand factor (vWF) type A domain; Region: VWA; smart00327
56110015984	metal ion-dependent adhesion site (MIDAS); other site
56110015985	AAA ATPase domain; Region: AAA_16; pfam13191
56110015986	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
56110015987	Walker A motif; other site
56110015988	ATP binding site [chemical binding]; other site
56110015989	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110015990	putative active site [active]
56110015991	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110015992	putative active site [active]
56110015993	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
56110015994	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
56110015995	HSP70 interaction site [polypeptide binding]; other site
56110015996	TPR repeat; Region: TPR_11; pfam13414
56110015997	Tetratricopeptide repeat; Region: TPR_2; pfam07719
56110015998	Clp protease; Region: CLP_protease; pfam00574
56110015999	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
56110016000	oligomer interface [polypeptide binding]; other site
56110016001	active site residues [active]
56110016002	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
56110016003	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
56110016004	oligomer interface [polypeptide binding]; other site
56110016005	active site residues [active]
56110016006	GTPase CgtA; Reviewed; Region: obgE; PRK12299
56110016007	GTP1/OBG; Region: GTP1_OBG; pfam01018
56110016008	Obg GTPase; Region: Obg; cd01898
56110016009	G1 box; other site
56110016010	GTP/Mg2+ binding site [chemical binding]; other site
56110016011	Switch I region; other site
56110016012	G2 box; other site
56110016013	G3 box; other site
56110016014	Switch II region; other site
56110016015	G4 box; other site
56110016016	G5 box; other site
56110016017	tellurium resistance terB-like protein; Region: terB_like; cd07177
56110016018	metal binding site [ion binding]; metal-binding site
56110016019	Mo-dependent nitrogenase C-terminus; Region: Mo-nitro_C; pfam06967
56110016020	hypothetical protein; Provisional; Region: PRK02724
56110016021	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
56110016022	haloacid dehalogenase superfamily, subfamily IA hydrolase, TIGR01548; Region: HAD-SF-IA-hyp1
56110016023	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016024	binding surface
56110016025	TPR motif; other site
56110016026	TPR repeat; Region: TPR_11; pfam13414
56110016027	TPR repeat; Region: TPR_11; pfam13414
56110016028	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016029	TPR motif; other site
56110016030	binding surface
56110016031	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
56110016032	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110016033	Walker A motif; other site
56110016034	ATP binding site [chemical binding]; other site
56110016035	Walker B motif; other site
56110016036	arginine finger; other site
56110016037	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
56110016038	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110016039	S-adenosylmethionine binding site [chemical binding]; other site
56110016040	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
56110016041	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
56110016042	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
56110016043	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
56110016044	Walker A/P-loop; other site
56110016045	ATP binding site [chemical binding]; other site
56110016046	Q-loop/lid; other site
56110016047	ABC transporter signature motif; other site
56110016048	Walker B; other site
56110016049	D-loop; other site
56110016050	H-loop/switch region; other site
56110016051	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
56110016052	putative carbohydrate binding site [chemical binding]; other site
56110016053	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3551
56110016054	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110016055	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110016056	active site
56110016057	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
56110016058	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; Region: GT2_RfbC_Mx_like; cd04184
56110016059	Probable Catalytic site; other site
56110016060	metal-binding site
56110016061	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110016062	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
56110016063	Probable Catalytic site; other site
56110016064	metal-binding site
56110016065	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110016066	Methyltransferase domain; Region: Methyltransf_23; pfam13489
56110016067	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
56110016068	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110016069	This family is most closely related to the GT1 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II); Region: GT1_ExpC_like; cd03818
56110016070	putative ADP-binding pocket [chemical binding]; other site
56110016071	Predicted permease; Region: DUF318; cl17795
56110016072	Predicted permease; Region: DUF318; cl17795
56110016073	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
56110016074	Putative phosphatase (DUF442); Region: DUF442; cl17385
56110016075	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
56110016076	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
56110016077	DNA binding residues [nucleotide binding]
56110016078	dimer interface [polypeptide binding]; other site
56110016079	metal binding site [ion binding]; metal-binding site
56110016080	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
56110016081	Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit and related proteins. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of...; Region: RuBisCO_small_like; cd00307
56110016082	putative multimerization interface [polypeptide binding]; other site
56110016083	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
56110016084	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
56110016085	G1 box; other site
56110016086	putative GEF interaction site [polypeptide binding]; other site
56110016087	GTP/Mg2+ binding site [chemical binding]; other site
56110016088	Switch I region; other site
56110016089	G2 box; other site
56110016090	G3 box; other site
56110016091	Switch II region; other site
56110016092	G4 box; other site
56110016093	G5 box; other site
56110016094	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
56110016095	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
56110016096	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
56110016097	Sulfate transporter family; Region: Sulfate_transp; pfam00916
56110016098	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
56110016099	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110016100	Ligand Binding Site [chemical binding]; other site
56110016101	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110016102	Ligand Binding Site [chemical binding]; other site
56110016103	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
56110016104	high affinity sulphate transporter 1; Region: sulP; TIGR00815
56110016105	Sulfate transporter family; Region: Sulfate_transp; pfam00916
56110016106	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
56110016107	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
56110016108	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
56110016109	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
56110016110	putative active site [active]
56110016111	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016112	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016113	active site
56110016114	ATP binding site [chemical binding]; other site
56110016115	substrate binding site [chemical binding]; other site
56110016116	activation loop (A-loop); other site
56110016117	Uncharacterized conserved protein [Function unknown]; Region: COG1262
56110016118	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
56110016119	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016120	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016121	active site
56110016122	ATP binding site [chemical binding]; other site
56110016123	substrate binding site [chemical binding]; other site
56110016124	activation loop (A-loop); other site
56110016125	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
56110016126	ATP-grasp domain; Region: ATP-grasp_4; cl17255
56110016127	SIR2-like domain; Region: SIR2_2; pfam13289
56110016128	Archaeal ATPase; Region: Arch_ATPase; pfam01637
56110016129	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110016130	Walker A motif; other site
56110016131	ATP binding site [chemical binding]; other site
56110016132	Walker B motif; other site
56110016133	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
56110016134	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
56110016135	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
56110016136	active site
56110016137	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14950
56110016138	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
56110016139	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
56110016140	dimerization interface [polypeptide binding]; other site
56110016141	domain crossover interface; other site
56110016142	redox-dependent activation switch; other site
56110016143	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
56110016144	catalytic residues [active]
56110016145	succinyldiaminopimelate transaminase; Validated; Region: PRK07366
56110016146	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
56110016147	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110016148	homodimer interface [polypeptide binding]; other site
56110016149	catalytic residue [active]
56110016150	PEP-CTERM protein-sorting domain; Region: PEP_exosort; TIGR02595
56110016151	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
56110016152	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
56110016153	Zn binding site [ion binding]; other site
56110016154	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110016155	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110016156	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110016157	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110016158	Domain of unknown function (DUF4351); Region: DUF4351; pfam14261
56110016159	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016160	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016161	active site
56110016162	ATP binding site [chemical binding]; other site
56110016163	substrate binding site [chemical binding]; other site
56110016164	activation loop (A-loop); other site
56110016165	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
56110016166	pseudouridine synthase; Region: TIGR00093
56110016167	active site
56110016168	hydrolase, alpha/beta fold family protein; Region: PLN02824
56110016169	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
56110016170	2-dehydropantoate 2-reductase; Provisional; Region: PRK06249
56110016171	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
56110016172	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
56110016173	hypothetical protein; Provisional; Region: PRK06208
56110016174	intersubunit interface [polypeptide binding]; other site
56110016175	active site
56110016176	Zn2+ binding site [ion binding]; other site
56110016177	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
56110016178	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
56110016179	Homeodomain-like domain; Region: HTH_23; pfam13384
56110016180	Winged helix-turn helix; Region: HTH_29; pfam13551
56110016181	Homeodomain-like domain; Region: HTH_32; pfam13565
56110016182	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110016183	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110016184	Amidohydrolase; Region: Amidohydro_2; pfam04909
56110016185	bacteriocin biosynthesis cyclodehydratase domain; Region: cyclo_dehyd_2; TIGR03882
56110016186	YcaO-like family; Region: YcaO; pfam02624
56110016187	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
56110016188	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
56110016189	Winged helix-turn helix; Region: HTH_29; pfam13551
56110016190	Homeodomain-like domain; Region: HTH_32; pfam13565
56110016191	Winged helix-turn helix; Region: HTH_33; pfam13592
56110016192	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110016193	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110016194	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110016195	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110016196	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110016197	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
56110016198	RsbT co-antagonist protein rsbRD N-terminal domain; Region: RsbRD_N; pfam14361
56110016199	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110016200	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016201	dimer interface [polypeptide binding]; other site
56110016202	phosphorylation site [posttranslational modification]
56110016203	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016204	ATP binding site [chemical binding]; other site
56110016205	Mg2+ binding site [ion binding]; other site
56110016206	G-X-G motif; other site
56110016207	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587
56110016208	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
56110016209	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586
56110016210	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110016211	Walker A/P-loop; other site
56110016212	ATP binding site [chemical binding]; other site
56110016213	Q-loop/lid; other site
56110016214	ABC transporter signature motif; other site
56110016215	Walker B; other site
56110016216	D-loop; other site
56110016217	H-loop/switch region; other site
56110016218	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
56110016219	recombination protein F; Reviewed; Region: recF; PRK00064
56110016220	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
56110016221	Walker A/P-loop; other site
56110016222	ATP binding site [chemical binding]; other site
56110016223	Q-loop/lid; other site
56110016224	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110016225	ABC transporter signature motif; other site
56110016226	Walker B; other site
56110016227	D-loop; other site
56110016228	H-loop/switch region; other site
56110016229	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110016230	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110016231	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
56110016232	Predicted ATPase of the ABC class; Region: ABC_ATPase; pfam09818
56110016233	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110016234	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110016235	S-adenosylmethionine binding site [chemical binding]; other site
56110016236	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
56110016237	active site
56110016238	SAM binding site [chemical binding]; other site
56110016239	homodimer interface [polypeptide binding]; other site
56110016240	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016241	dimer interface [polypeptide binding]; other site
56110016242	phosphorylation site [posttranslational modification]
56110016243	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016244	ATP binding site [chemical binding]; other site
56110016245	Mg2+ binding site [ion binding]; other site
56110016246	G-X-G motif; other site
56110016247	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
56110016248	anti sigma factor interaction site; other site
56110016249	regulatory phosphorylation site [posttranslational modification]; other site
56110016250	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5381
56110016251	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
56110016252	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
56110016253	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
56110016254	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
56110016255	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110016256	Walker A motif; other site
56110016257	ATP binding site [chemical binding]; other site
56110016258	Walker B motif; other site
56110016259	arginine finger; other site
56110016260	stage V sporulation protein K; Region: spore_V_K; TIGR02881
56110016261	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110016262	Walker A motif; other site
56110016263	ATP binding site [chemical binding]; other site
56110016264	Walker B motif; other site
56110016265	arginine finger; other site
56110016266	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
56110016267	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
56110016268	metal binding site [ion binding]; metal-binding site
56110016269	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
56110016270	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
56110016271	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110016272	dimerization interface [polypeptide binding]; other site
56110016273	putative DNA binding site [nucleotide binding]; other site
56110016274	putative Zn2+ binding site [ion binding]; other site
56110016275	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
56110016276	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
56110016277	ABC-ATPase subunit  interface; other site
56110016278	dimer interface [polypeptide binding]; other site
56110016279	putative PBP binding regions; other site
56110016280	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
56110016281	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
56110016282	putative active site; other site
56110016283	catalytic triad [active]
56110016284	putative dimer interface [polypeptide binding]; other site
56110016285	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
56110016286	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
56110016287	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
56110016288	proline aminopeptidase P II; Provisional; Region: PRK10879
56110016289	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
56110016290	active site
56110016291	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016292	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110016293	putative active site [active]
56110016294	heme pocket [chemical binding]; other site
56110016295	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016296	putative active site [active]
56110016297	heme pocket [chemical binding]; other site
56110016298	GAF domain; Region: GAF; cl17456
56110016299	GAF domain; Region: GAF_2; pfam13185
56110016300	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110016301	GAF domain; Region: GAF_3; pfam13492
56110016302	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110016303	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016304	dimer interface [polypeptide binding]; other site
56110016305	phosphorylation site [posttranslational modification]
56110016306	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016307	ATP binding site [chemical binding]; other site
56110016308	Mg2+ binding site [ion binding]; other site
56110016309	G-X-G motif; other site
56110016310	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110016311	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110016312	active site
56110016313	phosphorylation site [posttranslational modification]
56110016314	intermolecular recognition site; other site
56110016315	dimerization interface [polypeptide binding]; other site
56110016316	KGK domain; Region: KGK; pfam08872
56110016317	PAP_fibrillin; Region: PAP_fibrillin; pfam04755
56110016318	methionine sulfoxide reductase B; Provisional; Region: PRK00222
56110016319	SelR domain; Region: SelR; pfam01641
56110016320	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
56110016321	PAS fold; Region: PAS_4; pfam08448
56110016322	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016323	putative active site [active]
56110016324	heme pocket [chemical binding]; other site
56110016325	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110016326	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016327	putative active site [active]
56110016328	heme pocket [chemical binding]; other site
56110016329	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016330	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110016331	putative active site [active]
56110016332	heme pocket [chemical binding]; other site
56110016333	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016334	putative active site [active]
56110016335	heme pocket [chemical binding]; other site
56110016336	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016337	putative active site [active]
56110016338	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110016339	heme pocket [chemical binding]; other site
56110016340	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110016341	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016342	putative active site [active]
56110016343	heme pocket [chemical binding]; other site
56110016344	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016345	heme pocket [chemical binding]; other site
56110016346	putative active site [active]
56110016347	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110016348	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016349	putative active site [active]
56110016350	heme pocket [chemical binding]; other site
56110016351	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016352	dimer interface [polypeptide binding]; other site
56110016353	phosphorylation site [posttranslational modification]
56110016354	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016355	ATP binding site [chemical binding]; other site
56110016356	Mg2+ binding site [ion binding]; other site
56110016357	G-X-G motif; other site
56110016358	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110016359	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110016360	active site
56110016361	phosphorylation site [posttranslational modification]
56110016362	intermolecular recognition site; other site
56110016363	dimerization interface [polypeptide binding]; other site
56110016364	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
56110016365	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
56110016366	Uncharacterized family 1; belongs to a superfamily containing the transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this family was previously known as part of DUF156; Region: CsoR-like_DUF156_1; cd10158
56110016367	putative homodimer interface [polypeptide binding]; other site
56110016368	putative homotetramer interface [polypeptide binding]; other site
56110016369	putative metal binding site [ion binding]; other site
56110016370	putative homodimer-homodimer interface [polypeptide binding]; other site
56110016371	putative allosteric switch controlling residues; other site
56110016372	Membrane protein of unknown function; Region: DUF360; cl00850
56110016373	Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408
56110016374	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
56110016375	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110016376	This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802
56110016377	putative ADP-binding pocket [chemical binding]; other site
56110016378	Protein of unknown function (DUF760); Region: DUF760; pfam05542
56110016379	Bacterial Micro-Compartment (BMC)-like domain 1 repeat 1; Region: BMC_like_1_repeat1; cd07051
56110016380	putative hexamer interface [polypeptide binding]; other site
56110016381	putative hexagonal pore; other site
56110016382	Bacterial Micro-Compartment (BMC) domain; Region: BMC; cl01982
56110016383	Hexamer interface [polypeptide binding]; other site
56110016384	Hexagonal pore residue; other site
56110016385	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
56110016386	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
56110016387	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
56110016388	dimer interface [polypeptide binding]; other site
56110016389	active site
56110016390	glycine-pyridoxal phosphate binding site [chemical binding]; other site
56110016391	folate binding site [chemical binding]; other site
56110016392	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
56110016393	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
56110016394	substrate binding site [chemical binding]; other site
56110016395	ligand binding site [chemical binding]; other site
56110016396	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
56110016397	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
56110016398	substrate binding site [chemical binding]; other site
56110016399	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
56110016400	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
56110016401	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
56110016402	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
56110016403	RNA binding site [nucleotide binding]; other site
56110016404	circadian clock protein KaiC; Reviewed; Region: PRK09302
56110016405	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110016406	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110016407	Walker A motif; other site
56110016408	Walker A motif; other site
56110016409	ATP binding site [chemical binding]; other site
56110016410	Walker B motif; other site
56110016411	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
56110016412	Walker A motif; other site
56110016413	ATP binding site [chemical binding]; other site
56110016414	Walker B motif; other site
56110016415	KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part...; Region: KaiB_like; cd02978
56110016416	tetramer interface [polypeptide binding]; other site
56110016417	dimer interface [polypeptide binding]; other site
56110016418	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
56110016419	Carbon dioxide concentrating mechanism (CcmK); Bacterial Micro-Compartment (BCM) domain; Region: BMC_CcmK; cd07057
56110016420	Hexamer interface [polypeptide binding]; other site
56110016421	Hexagonal pore residue; other site
56110016422	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
56110016423	Bacterial Micro-Compartment (BMC) domain; Region: BMC; cl01982
56110016424	Hexamer interface [polypeptide binding]; other site
56110016425	Hexagonal pore residue; other site
56110016426	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
56110016427	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110016428	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110016429	S-adenosylmethionine binding site [chemical binding]; other site
56110016430	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110016431	dimerization interface [polypeptide binding]; other site
56110016432	putative DNA binding site [nucleotide binding]; other site
56110016433	putative Zn2+ binding site [ion binding]; other site
56110016434	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
56110016435	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
56110016436	metal-binding site [ion binding]
56110016437	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
56110016438	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
56110016439	metal-binding site [ion binding]
56110016440	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
56110016441	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
56110016442	metal-binding site [ion binding]
56110016443	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
56110016444	Soluble P-type ATPase [General function prediction only]; Region: COG4087
56110016445	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
56110016446	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110016447	dimer interface [polypeptide binding]; other site
56110016448	conserved gate region; other site
56110016449	putative PBP binding loops; other site
56110016450	ABC-ATPase subunit interface; other site
56110016451	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110016452	active site
56110016453	Protein of unknown function (DUF3038); Region: DUF3038; pfam11237
56110016454	Domain of unknown function (DUF4335); Region: DUF4335; pfam14233
56110016455	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
56110016456	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
56110016457	putative active site [active]
56110016458	substrate binding site [chemical binding]; other site
56110016459	putative cosubstrate binding site; other site
56110016460	catalytic site [active]
56110016461	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
56110016462	substrate binding site [chemical binding]; other site
56110016463	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
56110016464	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016465	active site
56110016466	ATP binding site [chemical binding]; other site
56110016467	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016468	substrate binding site [chemical binding]; other site
56110016469	activation loop (A-loop); other site
56110016470	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110016471	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110016472	putative active site [active]
56110016473	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
56110016474	A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292
56110016475	NAD binding site [chemical binding]; other site
56110016476	dimer interface [polypeptide binding]; other site
56110016477	substrate binding site [chemical binding]; other site
56110016478	tetramer (dimer of dimers) interface [polypeptide binding]; other site
56110016479	Photosystem I reaction centre subunit IV / PsaE; Region: PSI_PsaE; pfam02427
56110016480	formamidopyrimidine-DNA glycosylase; Provisional; Region: PRK13945
56110016481	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
56110016482	DNA binding site [nucleotide binding]
56110016483	catalytic residue [active]
56110016484	H2TH interface [polypeptide binding]; other site
56110016485	putative catalytic residues [active]
56110016486	turnover-facilitating residue; other site
56110016487	intercalation triad [nucleotide binding]; other site
56110016488	8OG recognition residue [nucleotide binding]; other site
56110016489	putative reading head residues; other site
56110016490	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
56110016491	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
56110016492	Cyanobacterial and plant NDH-1 subunit O; Region: NdhO; pfam11910
56110016493	malate dehydrogenase; Reviewed; Region: PRK06223
56110016494	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
56110016495	NAD(P) binding site [chemical binding]; other site
56110016496	dimer interface [polypeptide binding]; other site
56110016497	tetramer (dimer of dimers) interface [polypeptide binding]; other site
56110016498	substrate binding site [chemical binding]; other site
56110016499	AAA ATPase domain; Region: AAA_16; pfam13191
56110016500	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
56110016501	Beta-lactamase; Region: Beta-lactamase; pfam00144
56110016502	PAS domain S-box; Region: sensory_box; TIGR00229
56110016503	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016504	putative active site [active]
56110016505	heme pocket [chemical binding]; other site
56110016506	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110016507	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016508	putative active site [active]
56110016509	heme pocket [chemical binding]; other site
56110016510	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016511	putative active site [active]
56110016512	heme pocket [chemical binding]; other site
56110016513	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110016514	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110016515	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016516	dimer interface [polypeptide binding]; other site
56110016517	phosphorylation site [posttranslational modification]
56110016518	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016519	ATP binding site [chemical binding]; other site
56110016520	Mg2+ binding site [ion binding]; other site
56110016521	G-X-G motif; other site
56110016522	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016523	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016524	active site
56110016525	ATP binding site [chemical binding]; other site
56110016526	substrate binding site [chemical binding]; other site
56110016527	activation loop (A-loop); other site
56110016528	AAA ATPase domain; Region: AAA_16; pfam13191
56110016529	Predicted ATPase [General function prediction only]; Region: COG3899
56110016530	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110016531	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110016532	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110016533	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016534	dimer interface [polypeptide binding]; other site
56110016535	phosphorylation site [posttranslational modification]
56110016536	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016537	ATP binding site [chemical binding]; other site
56110016538	Mg2+ binding site [ion binding]; other site
56110016539	G-X-G motif; other site
56110016540	ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) [Nucleotide transport and metabolism]; Region: APA2; COG4360
56110016541	ATP adenylyltransferase; Region: ATP_transf; pfam09830
56110016542	DNA phosphorothioation system restriction enzyme; Region: dnd_restrict_1; TIGR04095
56110016543	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110016544	ATP binding site [chemical binding]; other site
56110016545	putative Mg++ binding site [ion binding]; other site
56110016546	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110016547	nucleotide binding region [chemical binding]; other site
56110016548	ATP-binding site [chemical binding]; other site
56110016549	DNA sulfur modification protein DndD; Region: DNA_S_dndD; TIGR03185
56110016550	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110016551	Walker A/P-loop; other site
56110016552	ATP binding site [chemical binding]; other site
56110016553	dnd system-associated protein 4; Region: dnd_assoc_4; TIGR04062
56110016554	DGQHR domain; Region: DGQHR; TIGR03187
56110016555	DNA-sulfur modification-associated; Region: DndB; cl17621
56110016556	DNA-sulfur modification-associated; Region: DndB; cl17621
56110016557	DGQHR domain; Region: DGQHR; TIGR03187
56110016558	DNA-sulfur modification-associated; Region: DndB; pfam14072
56110016559	hypothetical protein; Provisional; Region: PRK06850
56110016560	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
56110016561	Active Sites [active]
56110016562	DNA sulfur modification protein DndD; Region: DNA_S_dndD; TIGR03185
56110016563	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110016564	Walker A/P-loop; other site
56110016565	ATP binding site [chemical binding]; other site
56110016566	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110016567	ABC transporter signature motif; other site
56110016568	Walker B; other site
56110016569	D-loop; other site
56110016570	H-loop/switch region; other site
56110016571	Domain of unknown function (DUF1832); Region: DUF1832; pfam08870
56110016572	Protein of unknown function (DUF1499); Region: DUF1499; cl01841
56110016573	DNA phosphorothioation-associated putative methyltransferase; Region: dnd_rel_methyl; TIGR04096
56110016574	DNA phosphorothioation-associated putative methyltransferase; Region: dnd_rel_methyl; TIGR04096
56110016575	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110016576	putative active site [active]
56110016577	bifunctional orotidine 5'-phosphate decarboxylase/orotate phosphoribosyltransferase protein; Validated; Region: PRK05500
56110016578	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
56110016579	active site
56110016580	dimer interface [polypeptide binding]; other site
56110016581	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110016582	active site
56110016583	Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]; Region: COG4251
56110016584	GAF domain; Region: GAF; pfam01590
56110016585	Phytochrome region; Region: PHY; pfam00360
56110016586	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016587	ATP binding site [chemical binding]; other site
56110016588	Mg2+ binding site [ion binding]; other site
56110016589	G-X-G motif; other site
56110016590	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
56110016591	PLD-like domain; Region: PLDc_2; pfam13091
56110016592	putative active site [active]
56110016593	catalytic site [active]
56110016594	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
56110016595	PLD-like domain; Region: PLDc_2; pfam13091
56110016596	putative active site [active]
56110016597	catalytic site [active]
56110016598	HAMP domain; Region: HAMP; pfam00672
56110016599	dimerization interface [polypeptide binding]; other site
56110016600	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016601	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110016602	putative active site [active]
56110016603	heme pocket [chemical binding]; other site
56110016604	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016605	dimer interface [polypeptide binding]; other site
56110016606	phosphorylation site [posttranslational modification]
56110016607	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016608	ATP binding site [chemical binding]; other site
56110016609	Mg2+ binding site [ion binding]; other site
56110016610	G-X-G motif; other site
56110016611	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110016612	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110016613	active site
56110016614	phosphorylation site [posttranslational modification]
56110016615	intermolecular recognition site; other site
56110016616	dimerization interface [polypeptide binding]; other site
56110016617	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
56110016618	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
56110016619	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
56110016620	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
56110016621	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
56110016622	active site
56110016623	substrate-binding site [chemical binding]; other site
56110016624	metal-binding site [ion binding]
56110016625	ATP binding site [chemical binding]; other site
56110016626	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
56110016627	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
56110016628	active site
56110016629	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
56110016630	Pyruvate formate lyase 1; Region: PFL1; cd01678
56110016631	coenzyme A binding site [chemical binding]; other site
56110016632	active site
56110016633	catalytic residues [active]
56110016634	glycine loop; other site
56110016635	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
56110016636	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110016637	FeS/SAM binding site; other site
56110016638	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
56110016639	CoA binding domain; Region: CoA_binding_2; pfam13380
56110016640	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
56110016641	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
56110016642	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
56110016643	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110016644	Coenzyme A binding pocket [chemical binding]; other site
56110016645	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
56110016646	oligomeric interface; other site
56110016647	putative active site [active]
56110016648	homodimer interface [polypeptide binding]; other site
56110016649	Uncharacterized protein family (UPF0150); Region: UPF0150; cl00691
56110016650	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
56110016651	Uncharacterized conserved protein [Function unknown]; Region: COG5464
56110016652	Protein of unknown function (DUF2887); Region: DUF2887; pfam11103
56110016653	ornithine carbamoyltransferase; Provisional; Region: PRK00779
56110016654	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
56110016655	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
56110016656	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
56110016657	Na binding site [ion binding]; other site
56110016658	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
56110016659	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110016660	Coenzyme A binding pocket [chemical binding]; other site
56110016661	DNA methylase; Region: N6_N4_Mtase; cl17433
56110016662	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
56110016663	hypothetical protein; Provisional; Region: PRK04194
56110016664	tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Region: TIGR00057
56110016665	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
56110016666	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
56110016667	PHP domain; Region: PHP; pfam02811
56110016668	active site
56110016669	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
56110016670	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110016671	active site
56110016672	phosphorylation site [posttranslational modification]
56110016673	intermolecular recognition site; other site
56110016674	dimerization interface [polypeptide binding]; other site
56110016675	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
56110016676	DNA binding residues [nucleotide binding]
56110016677	dimerization interface [polypeptide binding]; other site
56110016678	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
56110016679	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
56110016680	ABC1 family; Region: ABC1; pfam03109
56110016681	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
56110016682	active site
56110016683	ATP binding site [chemical binding]; other site
56110016684	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110016685	cyclase homology domain; Region: CHD; cd07302
56110016686	nucleotidyl binding site; other site
56110016687	metal binding site [ion binding]; metal-binding site
56110016688	dimer interface [polypeptide binding]; other site
56110016689	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110016690	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110016691	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110016692	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110016693	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016694	PAS domain; Region: PAS_9; pfam13426
56110016695	putative active site [active]
56110016696	heme pocket [chemical binding]; other site
56110016697	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110016698	cyclase homology domain; Region: CHD; cd07302
56110016699	nucleotidyl binding site; other site
56110016700	metal binding site [ion binding]; metal-binding site
56110016701	dimer interface [polypeptide binding]; other site
56110016702	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
56110016703	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
56110016704	Walker A/P-loop; other site
56110016705	ATP binding site [chemical binding]; other site
56110016706	Q-loop/lid; other site
56110016707	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
56110016708	ABC transporter signature motif; other site
56110016709	Walker B; other site
56110016710	D-loop; other site
56110016711	H-loop/switch region; other site
56110016712	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
56110016713	dimer interface [polypeptide binding]; other site
56110016714	substrate binding site [chemical binding]; other site
56110016715	metal binding sites [ion binding]; metal-binding site
56110016716	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
56110016717	tetramerization interface [polypeptide binding]; other site
56110016718	active site
56110016719	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
56110016720	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
56110016721	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110016722	Probable transposase; Region: OrfB_IS605; pfam01385
56110016723	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
56110016724	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110016725	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110016726	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110016727	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110016728	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110016729	Tetrapyrrole (Corrin/Porphyrin) Methylases; Region: TP_methylase; pfam00590
56110016730	active site
56110016731	homodimer interface [polypeptide binding]; other site
56110016732	SAM binding site [chemical binding]; other site
56110016733	TPR repeat; Region: TPR_11; pfam13414
56110016734	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016735	binding surface
56110016736	TPR motif; other site
56110016737	TPR repeat; Region: TPR_11; pfam13414
56110016738	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016739	binding surface
56110016740	TPR motif; other site
56110016741	TPR repeat; Region: TPR_11; pfam13414
56110016742	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110016743	binding surface
56110016744	TPR motif; other site
56110016745	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110016746	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016747	TPR motif; other site
56110016748	binding surface
56110016749	TPR repeat; Region: TPR_11; pfam13414
56110016750	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016751	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110016752	TPR motif; other site
56110016753	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
56110016754	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016755	active site
56110016756	ATP binding site [chemical binding]; other site
56110016757	substrate binding site [chemical binding]; other site
56110016758	activation loop (A-loop); other site
56110016759	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110016760	AAA ATPase domain; Region: AAA_16; pfam13191
56110016761	Predicted ATPase [General function prediction only]; Region: COG3899
56110016762	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110016763	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110016764	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
56110016765	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110016766	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
56110016767	active site
56110016768	catalytic triad [active]
56110016769	oxyanion hole [active]
56110016770	DNA primase; Validated; Region: dnaG; PRK05667
56110016771	CHC2 zinc finger; Region: zf-CHC2; pfam01807
56110016772	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
56110016773	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
56110016774	active site
56110016775	metal binding site [ion binding]; metal-binding site
56110016776	interdomain interaction site; other site
56110016777	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
56110016778	apolar tunnel; other site
56110016779	heme binding site [chemical binding]; other site
56110016780	dimerization interface [polypeptide binding]; other site
56110016781	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
56110016782	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
56110016783	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
56110016784	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110016785	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
56110016786	NAD(P) binding site [chemical binding]; other site
56110016787	active site
56110016788	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
56110016789	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
56110016790	homodimer interface [polypeptide binding]; other site
56110016791	active site
56110016792	TDP-binding site; other site
56110016793	acceptor substrate-binding pocket; other site
56110016794	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110016795	active site
56110016796	Glycosyl transferase family 21; Region: Glyco_transf_21; pfam13506
56110016797	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110016798	active site
56110016799	Glycosyl transferase family 21; Region: Glyco_transf_21; pfam13506
56110016800	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK07204
56110016801	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
56110016802	dimer interface [polypeptide binding]; other site
56110016803	active site
56110016804	CoA binding pocket [chemical binding]; other site
56110016805	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110016806	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110016807	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110016808	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110016809	hypothetical protein; Reviewed; Region: PRK12497
56110016810	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
56110016811	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
56110016812	ribosomal protein L32; Validated; Region: rpl32; CHL00152
56110016813	Psb28 protein; Region: Psb28; cl04326
56110016814	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
56110016815	Nitrogen regulatory protein P-II; Region: P-II; smart00938
56110016816	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
56110016817	active site
56110016818	dimerization interface [polypeptide binding]; other site
56110016819	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
56110016820	This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible...; Region: PGM_like2; cd05800
56110016821	active site
56110016822	substrate binding site [chemical binding]; other site
56110016823	metal binding site [ion binding]; metal-binding site
56110016824	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
56110016825	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
56110016826	Manganese-stabilising protein / photosystem II polypeptide; Region: MSP; pfam01716
56110016827	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016828	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016829	active site
56110016830	ATP binding site [chemical binding]; other site
56110016831	substrate binding site [chemical binding]; other site
56110016832	activation loop (A-loop); other site
56110016833	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110016834	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110016835	structural tetrad; other site
56110016836	Protein of unknown function (DUF1822); Region: DUF1822; pfam08852
56110016837	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
56110016838	putative efflux protein, MATE family; Region: matE; TIGR00797
56110016839	cation binding site [ion binding]; other site
56110016840	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110016841	putative active site [active]
56110016842	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
56110016843	Transposase; Region: DDE_Tnp_ISL3; pfam01610
56110016844	Transposase domain (DUF772); Region: DUF772; pfam05598
56110016845	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110016846	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
56110016847	Domain of unknown function (DUF3368); Region: DUF3368; pfam11848
56110016848	Uncharacterized small protein [Function unknown]; Region: COG2886
56110016849	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016850	binding surface
56110016851	TPR motif; other site
56110016852	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110016853	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016854	TPR motif; other site
56110016855	binding surface
56110016856	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110016857	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016858	binding surface
56110016859	TPR motif; other site
56110016860	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110016861	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110016862	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016863	binding surface
56110016864	TPR motif; other site
56110016865	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110016866	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110016867	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110016868	TPR motif; other site
56110016869	binding surface
56110016870	FlxA-like protein; Region: FlxA; pfam14282
56110016871	CHAT domain; Region: CHAT; pfam12770
56110016872	Predicted transcription regulator containing HTH domain [Transcription]; Region: COG5499
56110016873	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
56110016874	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
56110016875	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
56110016876	Protein of unknown function (DUF1517); Region: DUF1517; pfam07466
56110016877	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
56110016878	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
56110016879	proposed catalytic triad [active]
56110016880	active site nucleophile [active]
56110016881	cyanophycin synthetase; Region: cya_phycin_syn; TIGR02068
56110016882	ATP-grasp domain; Region: ATP-grasp_4; cl17255
56110016883	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
56110016884	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
56110016885	phycocyanobilin:ferredoxin oxidoreductase; Validated; Region: PRK02816
56110016886	acylphosphatase; Provisional; Region: PRK14423
56110016887	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110016888	putative active site [active]
56110016889	Domain of unknown function DUF29; Region: DUF29; pfam01724
56110016890	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
56110016891	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
56110016892	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
56110016893	catalytic residue [active]
56110016894	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
56110016895	FeS assembly protein SufD; Region: sufD; TIGR01981
56110016896	sulfate ABC transporter protein; Validated; Region: ycf16; CHL00131
56110016897	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
56110016898	Walker A/P-loop; other site
56110016899	ATP binding site [chemical binding]; other site
56110016900	Q-loop/lid; other site
56110016901	ABC transporter signature motif; other site
56110016902	Walker B; other site
56110016903	D-loop; other site
56110016904	H-loop/switch region; other site
56110016905	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
56110016906	putative ABC transporter; Region: ycf24; CHL00085
56110016907	ferredoxin thioreductase subunit beta; Validated; Region: ftrB; CHL00165
56110016908	iron-sulfur cluster biosynthesis transcriptional regulator SufR; Region: SufR_cyano; TIGR02702
56110016909	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
56110016910	putative DNA binding site [nucleotide binding]; other site
56110016911	putative Zn2+ binding site [ion binding]; other site
56110016912	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
56110016913	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
56110016914	ligand binding site [chemical binding]; other site
56110016915	homodimer interface [polypeptide binding]; other site
56110016916	NAD(P) binding site [chemical binding]; other site
56110016917	trimer interface B [polypeptide binding]; other site
56110016918	trimer interface A [polypeptide binding]; other site
56110016919	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
56110016920	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
56110016921	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
56110016922	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
56110016923	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110016924	catalytic loop [active]
56110016925	iron binding site [ion binding]; other site
56110016926	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016927	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016928	active site
56110016929	ATP binding site [chemical binding]; other site
56110016930	substrate binding site [chemical binding]; other site
56110016931	activation loop (A-loop); other site
56110016932	Gas vesicle synthesis protein GvpL/GvpF; Region: GvpL_GvpF; pfam06386
56110016933	Phycobilisome protein; Region: Phycobilisome; cl08227
56110016934	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
56110016935	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110016936	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110016937	active site
56110016938	ATP binding site [chemical binding]; other site
56110016939	substrate binding site [chemical binding]; other site
56110016940	activation loop (A-loop); other site
56110016941	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
56110016942	AAA ATPase domain; Region: AAA_16; pfam13191
56110016943	Predicted ATPase [General function prediction only]; Region: COG3899
56110016944	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110016945	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110016946	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110016947	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016948	dimer interface [polypeptide binding]; other site
56110016949	phosphorylation site [posttranslational modification]
56110016950	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016951	ATP binding site [chemical binding]; other site
56110016952	Mg2+ binding site [ion binding]; other site
56110016953	G-X-G motif; other site
56110016954	Response regulator receiver domain; Region: Response_reg; pfam00072
56110016955	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110016956	active site
56110016957	phosphorylation site [posttranslational modification]
56110016958	intermolecular recognition site; other site
56110016959	dimerization interface [polypeptide binding]; other site
56110016960	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110016961	cyclase homology domain; Region: CHD; cd07302
56110016962	nucleotidyl binding site; other site
56110016963	metal binding site [ion binding]; metal-binding site
56110016964	dimer interface [polypeptide binding]; other site
56110016965	Archaeal ATPase; Region: Arch_ATPase; pfam01637
56110016966	AAA ATPase domain; Region: AAA_16; pfam13191
56110016967	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110016968	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110016969	structural tetrad; other site
56110016970	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110016971	structural tetrad; other site
56110016972	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110016973	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
56110016974	heat shock protein HtpX; Provisional; Region: PRK03982
56110016975	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
56110016976	ligand binding site [chemical binding]; other site
56110016977	PAS domain S-box; Region: sensory_box; TIGR00229
56110016978	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016979	putative active site [active]
56110016980	heme pocket [chemical binding]; other site
56110016981	PAS domain; Region: PAS_8; pfam13188
56110016982	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110016983	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016984	putative active site [active]
56110016985	heme pocket [chemical binding]; other site
56110016986	PAS domain S-box; Region: sensory_box; TIGR00229
56110016987	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110016988	putative active site [active]
56110016989	heme pocket [chemical binding]; other site
56110016990	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110016991	dimer interface [polypeptide binding]; other site
56110016992	phosphorylation site [posttranslational modification]
56110016993	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110016994	ATP binding site [chemical binding]; other site
56110016995	Mg2+ binding site [ion binding]; other site
56110016996	G-X-G motif; other site
56110016997	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110016998	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110016999	active site
56110017000	phosphorylation site [posttranslational modification]
56110017001	intermolecular recognition site; other site
56110017002	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110017003	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017004	dimer interface [polypeptide binding]; other site
56110017005	phosphorylation site [posttranslational modification]
56110017006	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017007	ATP binding site [chemical binding]; other site
56110017008	G-X-G motif; other site
56110017009	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110017010	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017011	active site
56110017012	phosphorylation site [posttranslational modification]
56110017013	intermolecular recognition site; other site
56110017014	dimerization interface [polypeptide binding]; other site
56110017015	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017016	GAF domain; Region: GAF; pfam01590
56110017017	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110017018	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017019	dimer interface [polypeptide binding]; other site
56110017020	phosphorylation site [posttranslational modification]
56110017021	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017022	ATP binding site [chemical binding]; other site
56110017023	Mg2+ binding site [ion binding]; other site
56110017024	G-X-G motif; other site
56110017025	Ycf46; Provisional; Region: ycf46; CHL00195
56110017026	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110017027	Walker A motif; other site
56110017028	ATP binding site [chemical binding]; other site
56110017029	Walker B motif; other site
56110017030	arginine finger; other site
56110017031	Protein of unknown function (DUF1257); Region: DUF1257; pfam06868
56110017032	Protein of unknown function (DUF1257); Region: DUF1257; cl06088
56110017033	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
56110017034	Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170
56110017035	nucleotide binding site [chemical binding]; other site
56110017036	putative NEF/HSP70 interaction site [polypeptide binding]; other site
56110017037	SBD interface [polypeptide binding]; other site
56110017038	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cl03075
56110017039	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
56110017040	Protein of unknown function (DUF2997); Region: DUF2997; pfam11211
56110017041	PhoD-like phosphatase; Region: PhoD; pfam09423
56110017042	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
56110017043	putative active site [active]
56110017044	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
56110017045	Domain of unknown function (DUF4325); Region: DUF4325; pfam14213
56110017046	Uncharacterized protein conserved in bacteria (DUF2191); Region: DUF2191; pfam09957
56110017047	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
56110017048	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
56110017049	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
56110017050	Macrophage migration inhibitory factor (MIF); Region: MIF; pfam01187
56110017051	Flavin reductase like domain; Region: Flavin_Reduct; pfam01613
56110017052	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
56110017053	active site
56110017054	SAM binding site [chemical binding]; other site
56110017055	homodimer interface [polypeptide binding]; other site
56110017056	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
56110017057	Uncharacterized conserved protein [Function unknown]; Region: COG2912
56110017058	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
56110017059	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017060	TPR motif; other site
56110017061	binding surface
56110017062	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cd07812
56110017063	hydrophobic ligand binding site; other site
56110017064	Conserved TM helix; Region: TM_helix; pfam05552
56110017065	Conserved TM helix; Region: TM_helix; pfam05552
56110017066	Conserved TM helix; Region: TM_helix; pfam05552
56110017067	Dynamin family; Region: Dynamin_N; pfam00350
56110017068	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
56110017069	G1 box; other site
56110017070	GTP/Mg2+ binding site [chemical binding]; other site
56110017071	Switch I region; other site
56110017072	G2 box; other site
56110017073	Switch II region; other site
56110017074	G3 box; other site
56110017075	G4 box; other site
56110017076	Domain of unknown function (DUF697); Region: DUF697; pfam05128
56110017077	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
56110017078	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
56110017079	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
56110017080	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
56110017081	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
56110017082	active site
56110017083	catalytic site [active]
56110017084	substrate binding site [chemical binding]; other site
56110017085	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
56110017086	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110017087	Coenzyme A binding pocket [chemical binding]; other site
56110017088	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
56110017089	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
56110017090	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
56110017091	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
56110017092	Coenzyme Q (ubiquinone) biosynthesis protein Coq4; Region: Coq4; cl02093
56110017093	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110017094	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110017095	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110017096	putative active site [active]
56110017097	putative NTP binding site [chemical binding]; other site
56110017098	putative nucleic acid binding site [nucleotide binding]; other site
56110017099	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110017100	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110017101	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110017102	active site
56110017103	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
56110017104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017105	ATP binding site [chemical binding]; other site
56110017106	Mg2+ binding site [ion binding]; other site
56110017107	G-X-G motif; other site
56110017108	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
56110017109	ATP binding site [chemical binding]; other site
56110017110	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
56110017111	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110017112	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
56110017113	active site
56110017114	catalytic residues [active]
56110017115	Bacterial SH3 domain; Region: SH3_3; pfam08239
56110017116	Protein kinase domain; Region: Pkinase; pfam00069
56110017117	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110017118	active site
56110017119	ATP binding site [chemical binding]; other site
56110017120	substrate binding site [chemical binding]; other site
56110017121	activation loop (A-loop); other site
56110017122	AAA ATPase domain; Region: AAA_16; pfam13191
56110017123	Predicted ATPase [General function prediction only]; Region: COG3899
56110017124	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017125	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017126	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017127	ATP binding site [chemical binding]; other site
56110017128	Mg2+ binding site [ion binding]; other site
56110017129	G-X-G motif; other site
56110017130	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
56110017131	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
56110017132	6-phosphofructokinase; Provisional; Region: PRK03202
56110017133	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
56110017134	active site
56110017135	ADP/pyrophosphate binding site [chemical binding]; other site
56110017136	dimerization interface [polypeptide binding]; other site
56110017137	allosteric effector site; other site
56110017138	fructose-1,6-bisphosphate binding site; other site
56110017139	Nuclease A inhibitor-like protein; Region: NuiA; pfam07924
56110017140	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
56110017141	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
56110017142	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
56110017143	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
56110017144	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
56110017145	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
56110017146	PsaD; Region: PsaD; pfam02531
56110017147	Sensory domain found in DIguanylate Cyclases & Two-component systems; Region: DICT; cl01731
56110017148	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017149	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110017150	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017151	dimer interface [polypeptide binding]; other site
56110017152	phosphorylation site [posttranslational modification]
56110017153	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017154	ATP binding site [chemical binding]; other site
56110017155	Mg2+ binding site [ion binding]; other site
56110017156	G-X-G motif; other site
56110017157	Ribbon-helix-helix domain; Region: RHH_4; cl01775
56110017158	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
56110017159	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
56110017160	Calcium binding; Region: Calci_bind_CcbP; pfam11535
56110017161	HEAT repeats; Region: HEAT_2; pfam13646
56110017162	HEAT repeats; Region: HEAT_2; pfam13646
56110017163	E-Z type HEAT repeats; Region: EZ_HEAT; smart00567
56110017164	HEAT repeats; Region: HEAT_2; pfam13646
56110017165	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
56110017166	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
56110017167	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
56110017168	active site
56110017169	Predicted permeases [General function prediction only]; Region: COG0679
56110017170	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
56110017171	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
56110017172	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
56110017173	binding surface
56110017174	Tetratricopeptide repeat; Region: TPR_9; pfam13371
56110017175	TPR motif; other site
56110017176	Peptidase family M48; Region: Peptidase_M48; cl12018
56110017177	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
56110017178	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
56110017179	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
56110017180	Tetramer interface [polypeptide binding]; other site
56110017181	active site
56110017182	FMN-binding site [chemical binding]; other site
56110017183	PAS fold; Region: PAS_3; pfam08447
56110017184	PAS domain S-box; Region: sensory_box; TIGR00229
56110017185	PAS domain S-box; Region: sensory_box; TIGR00229
56110017186	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017187	putative active site [active]
56110017188	heme pocket [chemical binding]; other site
56110017189	PAS domain S-box; Region: sensory_box; TIGR00229
56110017190	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017191	putative active site [active]
56110017192	heme pocket [chemical binding]; other site
56110017193	PAS fold; Region: PAS_3; pfam08447
56110017194	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017195	putative active site [active]
56110017196	heme pocket [chemical binding]; other site
56110017197	PAS fold; Region: PAS_4; pfam08448
56110017198	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017199	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017200	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110017201	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017202	dimer interface [polypeptide binding]; other site
56110017203	phosphorylation site [posttranslational modification]
56110017204	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017205	ATP binding site [chemical binding]; other site
56110017206	Mg2+ binding site [ion binding]; other site
56110017207	G-X-G motif; other site
56110017208	D1 subunit  of photosystem II (PS II); Region: Photosystem-II_D1; cd09289
56110017209	protein I interface; other site
56110017210	D2 interface; other site
56110017211	protein T interface; other site
56110017212	chlorophyll binding site; other site
56110017213	beta carotene binding site; other site
56110017214	pheophytin binding site; other site
56110017215	manganese-stabilizing polypeptide interface; other site
56110017216	CP43 interface; other site
56110017217	protein L interface; other site
56110017218	oxygen evolving complex binding site; other site
56110017219	bromide binding site; other site
56110017220	quinone binding site; other site
56110017221	Fe binding site [ion binding]; other site
56110017222	core light harvesting interface; other site
56110017223	cytochrome b559 alpha subunit interface; other site
56110017224	cytochrome c-550 interface; other site
56110017225	protein J interface; other site
56110017226	FO synthase subunit 1; Reviewed; Region: cofG; PRK06245
56110017227	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110017228	FeS/SAM binding site; other site
56110017229	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
56110017230	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110017231	active site
56110017232	metal binding site [ion binding]; metal-binding site
56110017233	hexamer interface [polypeptide binding]; other site
56110017234	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
56110017235	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
56110017236	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
56110017237	DNA binding residues [nucleotide binding]
56110017238	alpha-glucosidase; Provisional; Region: PRK10137
56110017239	Mannosyl oligosaccharide glucosidase; Region: Glyco_hydro_63; pfam03200
56110017240	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
56110017241	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
56110017242	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
56110017243	Ferritin-like; Region: Ferritin-like; pfam12902
56110017244	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017245	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110017246	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017247	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017248	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
56110017249	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
56110017250	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
56110017251	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
56110017252	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
56110017253	Glyoxal oxidase N-terminus; Region: Glyoxal_oxid_N; pfam07250
56110017254	C-terminal Early set domain associated with the catalytic domain of galactose oxidase; Region: E_set_GO_C; cd02851
56110017255	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
56110017256	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
56110017257	Aerobic Cyclase System Fe-containing subunit (ACSF), ferritin-like diiron-binding domain; Region: ACSF; cd01047
56110017258	diiron binding motif [ion binding]; other site
56110017259	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
56110017260	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110017261	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110017262	active site
56110017263	ATP binding site [chemical binding]; other site
56110017264	substrate binding site [chemical binding]; other site
56110017265	activation loop (A-loop); other site
56110017266	TM2 domain; Region: TM2; cl00984
56110017267	Protein of unknown function (DUF2996); Region: DUF2996; pfam11210
56110017268	CpeS-like protein; Region: CpeS; pfam09367
56110017269	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110017270	FOG: CBS domain [General function prediction only]; Region: COG0517
56110017271	FOG: CBS domain [General function prediction only]; Region: COG0517
56110017272	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with a PAS domain, a GGDEF (DiGuanylate-Cyclase (DGC) domain, and a DUF1 domain downstream. PAS domains have been found to bind ligands, and to act...; Region: CBS_pair_PAS_GGDEF_DUF1_assoc; cd04611
56110017273	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017274	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017275	PAS domain S-box; Region: sensory_box; TIGR00229
56110017276	PAS domain; Region: PAS; smart00091
56110017277	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017278	GAF domain; Region: GAF_3; pfam13492
56110017279	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
56110017280	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110017281	metal binding site [ion binding]; metal-binding site
56110017282	active site
56110017283	I-site; other site
56110017284	OstA-like protein; Region: OstA; cl00844
56110017285	Protein of unknown function (DUF3769); Region: DUF3769; pfam12600
56110017286	photosystem II reaction center I protein I; Provisional; Region: psbI; PRK02655
56110017287	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
56110017288	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
56110017289	active site
56110017290	catalytic site [active]
56110017291	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
56110017292	PRC-barrel domain; Region: PRC; pfam05239
56110017293	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3861
56110017294	S-layer homology domain; Region: SLH; pfam00395
56110017295	S-layer homology domain; Region: SLH; pfam00395
56110017296	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110017297	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017298	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110017299	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017300	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017301	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
56110017302	RuvA N terminal domain; Region: RuvA_N; pfam01330
56110017303	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
56110017304	sucrose-6F-phosphate phosphohydrolase; Region: SPP_plant-cyano; TIGR01485
56110017305	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110017306	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
56110017307	active site
56110017308	metal binding site [ion binding]; metal-binding site
56110017309	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
56110017310	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
56110017311	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110017312	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110017313	structural tetrad; other site
56110017314	Domain of unknown function (DUF4404); Region: DUF4404; pfam14357
56110017315	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110017316	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110017317	structural tetrad; other site
56110017318	PAS fold; Region: PAS_4; pfam08448
56110017319	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017320	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110017321	putative active site [active]
56110017322	heme pocket [chemical binding]; other site
56110017323	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017324	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110017325	putative active site [active]
56110017326	heme pocket [chemical binding]; other site
56110017327	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110017328	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017329	putative active site [active]
56110017330	heme pocket [chemical binding]; other site
56110017331	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017332	putative active site [active]
56110017333	heme pocket [chemical binding]; other site
56110017334	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017335	GAF domain; Region: GAF; cl17456
56110017336	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017337	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017338	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017339	dimer interface [polypeptide binding]; other site
56110017340	phosphorylation site [posttranslational modification]
56110017341	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017342	ATP binding site [chemical binding]; other site
56110017343	Mg2+ binding site [ion binding]; other site
56110017344	G-X-G motif; other site
56110017345	Response regulator receiver domain; Region: Response_reg; pfam00072
56110017346	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017347	active site
56110017348	phosphorylation site [posttranslational modification]
56110017349	intermolecular recognition site; other site
56110017350	dimerization interface [polypeptide binding]; other site
56110017351	Response regulator receiver domain; Region: Response_reg; pfam00072
56110017352	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017353	active site
56110017354	phosphorylation site [posttranslational modification]
56110017355	intermolecular recognition site; other site
56110017356	dimerization interface [polypeptide binding]; other site
56110017357	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110017358	putative binding surface; other site
56110017359	active site
56110017360	Protein of unknown function (DUF3571); Region: DUF3571; pfam12095
56110017361	Protein of unknown function (DUF2854); Region: DUF2854; pfam11016
56110017362	polyphosphate kinase; Provisional; Region: PRK05443
56110017363	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
56110017364	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
56110017365	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
56110017366	putative domain interface [polypeptide binding]; other site
56110017367	putative active site [active]
56110017368	catalytic site [active]
56110017369	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
56110017370	putative domain interface [polypeptide binding]; other site
56110017371	putative active site [active]
56110017372	catalytic site [active]
56110017373	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
56110017374	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
56110017375	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
56110017376	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
56110017377	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
56110017378	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
56110017379	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
56110017380	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
56110017381	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
56110017382	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
56110017383	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
56110017384	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017385	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017386	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017387	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017388	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110017389	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017390	ATP binding site [chemical binding]; other site
56110017391	Mg2+ binding site [ion binding]; other site
56110017392	G-X-G motif; other site
56110017393	pantothenate kinase; Reviewed; Region: PRK13331
56110017394	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
56110017395	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
56110017396	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
56110017397	nucleophilic elbow; other site
56110017398	catalytic site [active]
56110017399	catalytic triad; other site
56110017400	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
56110017401	nudix motif; other site
56110017402	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110017403	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110017404	structural tetrad; other site
56110017405	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110017406	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110017407	structural tetrad; other site
56110017408	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
56110017409	16S/18S rRNA binding site [nucleotide binding]; other site
56110017410	S13e-L30e interaction site [polypeptide binding]; other site
56110017411	25S rRNA binding site [nucleotide binding]; other site
56110017412	Protein of unknown function (DUF3464); Region: DUF3464; pfam11947
56110017413	3-deoxy-7-phosphoheptulonate synthase; Provisional; Region: PRK13396
56110017414	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
56110017415	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
56110017416	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110017417	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110017418	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110017419	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
56110017420	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
56110017421	Uncharacterized ACR (DUF711); Region: DUF711; pfam05167
56110017422	Biofilm formation and stress response factor; Region: BsmA; cl01794
56110017423	CHAT domain; Region: CHAT; pfam12770
56110017424	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017425	binding surface
56110017426	TPR motif; other site
56110017427	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017428	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017429	binding surface
56110017430	TPR motif; other site
56110017431	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017432	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017433	binding surface
56110017434	TPR motif; other site
56110017435	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017436	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017437	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017438	binding surface
56110017439	TPR motif; other site
56110017440	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017441	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017442	binding surface
56110017443	TPR motif; other site
56110017444	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017445	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017446	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017447	TPR motif; other site
56110017448	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017449	binding surface
56110017450	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
56110017451	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
56110017452	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110017453	Q-loop/lid; other site
56110017454	ABC transporter signature motif; other site
56110017455	Walker B; other site
56110017456	D-loop; other site
56110017457	H-loop/switch region; other site
56110017458	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017459	putative active site [active]
56110017460	heme pocket [chemical binding]; other site
56110017461	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110017462	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017463	dimer interface [polypeptide binding]; other site
56110017464	phosphorylation site [posttranslational modification]
56110017465	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017466	ATP binding site [chemical binding]; other site
56110017467	Mg2+ binding site [ion binding]; other site
56110017468	G-X-G motif; other site
56110017469	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110017470	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017471	active site
56110017472	phosphorylation site [posttranslational modification]
56110017473	intermolecular recognition site; other site
56110017474	dimerization interface [polypeptide binding]; other site
56110017475	Transposase domain (DUF772); Region: DUF772; pfam05598
56110017476	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
56110017477	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
56110017478	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
56110017479	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
56110017480	active site
56110017481	HIGH motif; other site
56110017482	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
56110017483	KMSKS motif; other site
56110017484	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
56110017485	tRNA binding surface [nucleotide binding]; other site
56110017486	anticodon binding site; other site
56110017487	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110017488	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110017489	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
56110017490	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110017491	Methyltransferase domain; Region: Methyltransf_31; pfam13847
56110017492	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110017493	S-adenosylmethionine binding site [chemical binding]; other site
56110017494	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
56110017495	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
56110017496	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
56110017497	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
56110017498	putative active site [active]
56110017499	dimerization interface [polypeptide binding]; other site
56110017500	putative tRNAtyr binding site [nucleotide binding]; other site
56110017501	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
56110017502	rod shape-determining protein MreC; Provisional; Region: PRK13922
56110017503	rod shape-determining protein MreC; Region: MreC; pfam04085
56110017504	rod shape-determining protein MreB; Provisional; Region: PRK13927
56110017505	MreB and similar proteins; Region: MreB_like; cd10225
56110017506	nucleotide binding site [chemical binding]; other site
56110017507	Mg binding site [ion binding]; other site
56110017508	putative protofilament interaction site [polypeptide binding]; other site
56110017509	RodZ interaction site [polypeptide binding]; other site
56110017510	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
56110017511	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
56110017512	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
56110017513	NAD(P) binding site [chemical binding]; other site
56110017514	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
56110017515	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
56110017516	substrate binding site [chemical binding]; other site
56110017517	glutamase interaction surface [polypeptide binding]; other site
56110017518	Protein of unknown function (DUF2862); Region: DUF2862; pfam11061
56110017519	Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: ArsA; COG0003
56110017520	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
56110017521	P loop; other site
56110017522	Nucleotide binding site [chemical binding]; other site
56110017523	DTAP/Switch II; other site
56110017524	Switch I; other site
56110017525	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
56110017526	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
56110017527	UbiA prenyltransferase family; Region: UbiA; pfam01040
56110017528	Transglycosylase; Region: Transgly; pfam00912
56110017529	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
56110017530	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
56110017531	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110017532	AAA domain; Region: AAA_21; pfam13304
56110017533	Walker A/P-loop; other site
56110017534	ATP binding site [chemical binding]; other site
56110017535	16S rRNA methyltransferase B; Provisional; Region: PRK14901
56110017536	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
56110017537	putative RNA binding site [nucleotide binding]; other site
56110017538	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110017539	S-adenosylmethionine binding site [chemical binding]; other site
56110017540	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
56110017541	PAS domain; Region: PAS; smart00091
56110017542	PAS fold; Region: PAS_4; pfam08448
56110017543	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017544	PAS domain; Region: PAS_9; pfam13426
56110017545	putative active site [active]
56110017546	heme pocket [chemical binding]; other site
56110017547	PAS domain S-box; Region: sensory_box; TIGR00229
56110017548	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017549	putative active site [active]
56110017550	heme pocket [chemical binding]; other site
56110017551	PAS domain S-box; Region: sensory_box; TIGR00229
56110017552	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017553	putative active site [active]
56110017554	heme pocket [chemical binding]; other site
56110017555	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110017556	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017557	putative active site [active]
56110017558	heme pocket [chemical binding]; other site
56110017559	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017560	dimer interface [polypeptide binding]; other site
56110017561	phosphorylation site [posttranslational modification]
56110017562	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017563	ATP binding site [chemical binding]; other site
56110017564	Mg2+ binding site [ion binding]; other site
56110017565	G-X-G motif; other site
56110017566	Response regulator receiver domain; Region: Response_reg; pfam00072
56110017567	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017568	active site
56110017569	phosphorylation site [posttranslational modification]
56110017570	intermolecular recognition site; other site
56110017571	dimerization interface [polypeptide binding]; other site
56110017572	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110017573	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017574	active site
56110017575	phosphorylation site [posttranslational modification]
56110017576	intermolecular recognition site; other site
56110017577	dimerization interface [polypeptide binding]; other site
56110017578	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110017579	putative binding surface; other site
56110017580	active site
56110017581	Protein of unknown function (DUF3616); Region: DUF3616; pfam12275
56110017582	Coenzyme F420-reducing hydrogenase, beta subunit [Energy production and conversion]; Region: FrhB; COG1035
56110017583	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Region: FrhB_FdhB_N; pfam04422
56110017584	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; Region: FrhB_FdhB_C; pfam04432
56110017585	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110017586	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017587	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017588	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017589	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017590	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017591	Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones]; Region: COG4067
56110017592	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
56110017593	RimK-like ATP-grasp domain; Region: RimK; pfam08443
56110017594	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_1; cd06251
56110017595	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
56110017596	putative active site [active]
56110017597	Zn binding site [ion binding]; other site
56110017598	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
56110017599	Aluminium resistance protein; Region: Alum_res; pfam06838
56110017600	Fatty acid desaturase; Region: FA_desaturase; pfam00487
56110017601	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
56110017602	Di-iron ligands [ion binding]; other site
56110017603	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
56110017604	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
56110017605	putative catalytic cysteine [active]
56110017606	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
56110017607	homopentamer interface [polypeptide binding]; other site
56110017608	active site
56110017609	photosystem II reaction center protein Z; Provisional; Region: psbZ; PRK02576
56110017610	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
56110017611	DHH family; Region: DHH; pfam01368
56110017612	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110017613	FOG: CBS domain [General function prediction only]; Region: COG0517
56110017614	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with an upstream DHH domain which performs a phosphoesterase function and a downstream polyA polymerase domain. CBS is a small domain originally...; Region: CBS_pair_DHH_polyA_Pol_assoc; cd04595
56110017615	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
56110017616	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
56110017617	active site
56110017618	NTP binding site [chemical binding]; other site
56110017619	metal binding triad [ion binding]; metal-binding site
56110017620	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
56110017621	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
56110017622	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017623	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110017624	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017625	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017626	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017627	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110017628	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017629	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017630	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
56110017631	phosphopeptide binding site; other site
56110017632	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017633	GTP-binding protein YchF; Reviewed; Region: PRK09601
56110017634	YchF GTPase; Region: YchF; cd01900
56110017635	G1 box; other site
56110017636	GTP/Mg2+ binding site [chemical binding]; other site
56110017637	Switch I region; other site
56110017638	G2 box; other site
56110017639	Switch II region; other site
56110017640	G3 box; other site
56110017641	G4 box; other site
56110017642	G5 box; other site
56110017643	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
56110017644	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110017645	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110017646	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110017647	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110017648	active site
56110017649	ATP binding site [chemical binding]; other site
56110017650	substrate binding site [chemical binding]; other site
56110017651	activation loop (A-loop); other site
56110017652	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
56110017653	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
56110017654	hinge; other site
56110017655	active site
56110017656	Neisseria meningitidis TspB protein; Region: Neisseria_TspB; pfam05616
56110017657	Domain of unknown function (DUF4308); Region: DUF4308; pfam14159
56110017658	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
56110017659	Clostridial hydrophobic W; Region: ChW; pfam07538
56110017660	cobalamin synthase; Reviewed; Region: cobS; PRK00235
56110017661	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
56110017662	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
56110017663	Photosystem II 4 kDa reaction centre component; Region: PsbK; pfam02533
56110017664	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
56110017665	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
56110017666	putative C-terminal domain interface [polypeptide binding]; other site
56110017667	putative GSH binding site (G-site) [chemical binding]; other site
56110017668	putative dimer interface [polypeptide binding]; other site
56110017669	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
56110017670	N-terminal domain interface [polypeptide binding]; other site
56110017671	dimer interface [polypeptide binding]; other site
56110017672	substrate binding pocket (H-site) [chemical binding]; other site
56110017673	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017674	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017675	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110017676	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017677	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110017678	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017679	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017680	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017681	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110017682	DNA polymerase I; Provisional; Region: PRK05755
56110017683	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
56110017684	active site
56110017685	metal binding site 1 [ion binding]; metal-binding site
56110017686	putative 5' ssDNA interaction site; other site
56110017687	metal binding site 3; metal-binding site
56110017688	metal binding site 2 [ion binding]; metal-binding site
56110017689	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
56110017690	putative DNA binding site [nucleotide binding]; other site
56110017691	putative metal binding site [ion binding]; other site
56110017692	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
56110017693	active site
56110017694	catalytic site [active]
56110017695	substrate binding site [chemical binding]; other site
56110017696	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
56110017697	active site
56110017698	DNA binding site [nucleotide binding]
56110017699	catalytic site [active]
56110017700	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
56110017701	propionate/acetate kinase; Provisional; Region: PRK12379
56110017702	putative phosphoketolase; Provisional; Region: PRK05261
56110017703	XFP N-terminal domain; Region: XFP_N; pfam09364
56110017704	XFP C-terminal domain; Region: XFP_C; pfam09363
56110017705	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
56110017706	MOSC domain; Region: MOSC; pfam03473
56110017707	Iron permease FTR1 family; Region: FTR1; cl00475
56110017708	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
56110017709	dinuclear metal binding motif [ion binding]; other site
56110017710	Ferritin-like domain; Region: Ferritin; pfam00210
56110017711	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
56110017712	dinuclear metal binding motif [ion binding]; other site
56110017713	Domain of unknown function (DUF4198); Region: DUF4198; pfam10670
56110017714	cobalt transport protein CbiM; Validated; Region: PRK06265
56110017715	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
56110017716	cobalt ABC transporter, permease protein CbiQ; Region: CbiQ_TIGR; TIGR02454
56110017717	Ion transport protein; Region: Ion_trans; pfam00520
56110017718	Ion channel; Region: Ion_trans_2; pfam07885
56110017719	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
56110017720	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
56110017721	Walker A/P-loop; other site
56110017722	ATP binding site [chemical binding]; other site
56110017723	Q-loop/lid; other site
56110017724	ABC transporter signature motif; other site
56110017725	Walker B; other site
56110017726	D-loop; other site
56110017727	H-loop/switch region; other site
56110017728	Predicted membrane protein [Function unknown]; Region: COG1950
56110017729	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
56110017730	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110017731	cofactor binding site; other site
56110017732	DNA binding site [nucleotide binding]
56110017733	substrate interaction site [chemical binding]; other site
56110017734	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
56110017735	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
56110017736	ABC-2 type transporter; Region: ABC2_membrane; cl17235
56110017737	Uncharacterized ACR, YggU family COG1872; Region: DUF167; pfam02594
56110017738	3-hydroxyanthranilic acid dioxygenase; Region: 3-HAO; cl17399
56110017739	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
56110017740	intracellular protease, PfpI family; Region: PfpI; TIGR01382
56110017741	conserved cys residue [active]
56110017742	PetN; Region: PetN; pfam03742
56110017743	Domain of unknown function (DUF4347); Region: DUF4347; pfam14252
56110017744	Beta-propeller repeat; Region: SBBP; pfam06739
56110017745	Beta-propeller repeat; Region: SBBP; pfam06739
56110017746	Beta-propeller repeat; Region: SBBP; pfam06739
56110017747	Calx-beta domain; Region: Calx-beta; cl02522
56110017748	Calx-beta domain; Region: Calx-beta; cl02522
56110017749	Calx-beta domain; Region: Calx-beta; cl02522
56110017750	Calx-beta domain; Region: Calx-beta; cl02522
56110017751	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
56110017752	Family description; Region: UvrD_C_2; pfam13538
56110017753	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
56110017754	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110017755	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110017756	active site
56110017757	ATP binding site [chemical binding]; other site
56110017758	substrate binding site [chemical binding]; other site
56110017759	activation loop (A-loop); other site
56110017760	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110017761	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110017762	active site
56110017763	ATP binding site [chemical binding]; other site
56110017764	substrate binding site [chemical binding]; other site
56110017765	activation loop (A-loop); other site
56110017766	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110017767	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110017768	active site
56110017769	ATP binding site [chemical binding]; other site
56110017770	substrate binding site [chemical binding]; other site
56110017771	activation loop (A-loop); other site
56110017772	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
56110017773	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
56110017774	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
56110017775	putative active site [active]
56110017776	Protein of unknown function (DUF3110); Region: DUF3110; pfam11360
56110017777	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
56110017778	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
56110017779	Family of unknown function (DUF490); Region: DUF490; pfam04357
56110017780	AAA ATPase domain; Region: AAA_16; pfam13191
56110017781	E3 ubiquitin-protein ligase UBR4; Region: E3_UbLigase_R4; pfam13764
56110017782	Domain of unknown function (DUF4258); Region: DUF4258; pfam14076
56110017783	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
56110017784	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110017785	dimer interface [polypeptide binding]; other site
56110017786	conserved gate region; other site
56110017787	putative PBP binding loops; other site
56110017788	ABC-ATPase subunit interface; other site
56110017789	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110017790	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017791	active site
56110017792	phosphorylation site [posttranslational modification]
56110017793	intermolecular recognition site; other site
56110017794	dimerization interface [polypeptide binding]; other site
56110017795	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
56110017796	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017797	putative active site [active]
56110017798	heme pocket [chemical binding]; other site
56110017799	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017800	dimer interface [polypeptide binding]; other site
56110017801	phosphorylation site [posttranslational modification]
56110017802	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017803	ATP binding site [chemical binding]; other site
56110017804	Mg2+ binding site [ion binding]; other site
56110017805	G-X-G motif; other site
56110017806	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
56110017807	Histidine kinase; Region: HisKA_2; pfam07568
56110017808	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017809	ATP binding site [chemical binding]; other site
56110017810	Mg2+ binding site [ion binding]; other site
56110017811	G-X-G motif; other site
56110017812	Transposase domain (DUF772); Region: DUF772; pfam05598
56110017813	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
56110017814	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110017815	FOG: CBS domain [General function prediction only]; Region: COG0517
56110017816	FOG: CBS domain [General function prediction only]; Region: COG0517
56110017817	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
56110017818	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017819	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110017820	putative active site [active]
56110017821	heme pocket [chemical binding]; other site
56110017822	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017823	putative active site [active]
56110017824	heme pocket [chemical binding]; other site
56110017825	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017826	PAS fold; Region: PAS_3; pfam08447
56110017827	putative active site [active]
56110017828	heme pocket [chemical binding]; other site
56110017829	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017830	PAS domain; Region: PAS_9; pfam13426
56110017831	putative active site [active]
56110017832	heme pocket [chemical binding]; other site
56110017833	PAS fold; Region: PAS_4; pfam08448
56110017834	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017835	PAS fold; Region: PAS_3; pfam08447
56110017836	putative active site [active]
56110017837	heme pocket [chemical binding]; other site
56110017838	Response regulator receiver domain; Region: Response_reg; pfam00072
56110017839	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017840	active site
56110017841	phosphorylation site [posttranslational modification]
56110017842	intermolecular recognition site; other site
56110017843	dimerization interface [polypeptide binding]; other site
56110017844	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
56110017845	metal binding site [ion binding]; metal-binding site
56110017846	active site
56110017847	I-site; other site
56110017848	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
56110017849	Response regulator receiver domain; Region: Response_reg; pfam00072
56110017850	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017851	active site
56110017852	phosphorylation site [posttranslational modification]
56110017853	intermolecular recognition site; other site
56110017854	dimerization interface [polypeptide binding]; other site
56110017855	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110017856	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017857	dimer interface [polypeptide binding]; other site
56110017858	phosphorylation site [posttranslational modification]
56110017859	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
56110017860	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
56110017861	Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980
56110017862	ribosome maturation protein RimP; Reviewed; Region: PRK00092
56110017863	Sm and related proteins; Region: Sm_like; cl00259
56110017864	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
56110017865	putative oligomer interface [polypeptide binding]; other site
56110017866	putative RNA binding site [nucleotide binding]; other site
56110017867	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
56110017868	NusA N-terminal domain; Region: NusA_N; pfam08529
56110017869	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
56110017870	RNA binding site [nucleotide binding]; other site
56110017871	homodimer interface [polypeptide binding]; other site
56110017872	NusA-like KH domain; Region: KH_5; pfam13184
56110017873	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
56110017874	G-X-X-G motif; other site
56110017875	Protein of unknown function (DUF448); Region: DUF448; pfam04296
56110017876	putative RNA binding cleft [nucleotide binding]; other site
56110017877	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
56110017878	translation initiation factor IF-2; Region: IF-2; TIGR00487
56110017879	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
56110017880	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
56110017881	G1 box; other site
56110017882	putative GEF interaction site [polypeptide binding]; other site
56110017883	GTP/Mg2+ binding site [chemical binding]; other site
56110017884	Switch I region; other site
56110017885	G2 box; other site
56110017886	G3 box; other site
56110017887	Switch II region; other site
56110017888	G4 box; other site
56110017889	G5 box; other site
56110017890	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
56110017891	Translation-initiation factor 2; Region: IF-2; pfam11987
56110017892	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
56110017893	Alpha/beta hydrolase of unknown function (DUF1400); Region: DUF1400; pfam07176
56110017894	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
56110017895	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
56110017896	S-layer homology domain; Region: SLH; pfam00395
56110017897	S-layer homology domain; Region: SLH; pfam00395
56110017898	S-layer homology domain; Region: SLH; pfam00395
56110017899	Protein of unknown function (DUF3493); Region: DUF3493; pfam11998
56110017900	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_2; cd06160
56110017901	Peptidase family M50; Region: Peptidase_M50; pfam02163
56110017902	active site
56110017903	putative substrate binding region [chemical binding]; other site
56110017904	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110017905	S-adenosylmethionine binding site [chemical binding]; other site
56110017906	PAS domain; Region: PAS_9; pfam13426
56110017907	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017908	putative active site [active]
56110017909	heme pocket [chemical binding]; other site
56110017910	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017911	GAF domain; Region: GAF; pfam01590
56110017912	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017913	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017914	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017915	dimer interface [polypeptide binding]; other site
56110017916	phosphorylation site [posttranslational modification]
56110017917	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017918	ATP binding site [chemical binding]; other site
56110017919	Mg2+ binding site [ion binding]; other site
56110017920	G-X-G motif; other site
56110017921	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110017922	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017923	active site
56110017924	phosphorylation site [posttranslational modification]
56110017925	intermolecular recognition site; other site
56110017926	dimerization interface [polypeptide binding]; other site
56110017927	Response regulator receiver domain; Region: Response_reg; pfam00072
56110017928	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017929	active site
56110017930	phosphorylation site [posttranslational modification]
56110017931	intermolecular recognition site; other site
56110017932	dimerization interface [polypeptide binding]; other site
56110017933	PAS domain S-box; Region: sensory_box; TIGR00229
56110017934	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110017935	putative active site [active]
56110017936	heme pocket [chemical binding]; other site
56110017937	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110017938	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110017939	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110017940	dimer interface [polypeptide binding]; other site
56110017941	phosphorylation site [posttranslational modification]
56110017942	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110017943	ATP binding site [chemical binding]; other site
56110017944	Mg2+ binding site [ion binding]; other site
56110017945	G-X-G motif; other site
56110017946	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110017947	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
56110017948	active site
56110017949	phosphorylation site [posttranslational modification]
56110017950	intermolecular recognition site; other site
56110017951	dimerization interface [polypeptide binding]; other site
56110017952	Response regulator receiver domain; Region: Response_reg; pfam00072
56110017953	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110017954	active site
56110017955	phosphorylation site [posttranslational modification]
56110017956	intermolecular recognition site; other site
56110017957	dimerization interface [polypeptide binding]; other site
56110017958	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
56110017959	putative binding surface; other site
56110017960	active site
56110017961	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
56110017962	Ligand binding site; other site
56110017963	Putative Catalytic site; other site
56110017964	DXD motif; other site
56110017965	Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993
56110017966	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) [Signal transduction mechanisms]; Region: COG3476
56110017967	PQQ-like domain; Region: PQQ_2; pfam13360
56110017968	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110017969	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110017970	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
56110017971	S-layer homology domain; Region: SLH; pfam00395
56110017972	S-layer homology domain; Region: SLH; pfam00395
56110017973	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
56110017974	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
56110017975	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017976	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017977	binding surface
56110017978	TPR motif; other site
56110017979	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017980	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017981	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017982	binding surface
56110017983	TPR motif; other site
56110017984	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017985	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017986	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017987	TPR motif; other site
56110017988	binding surface
56110017989	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017990	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017991	binding surface
56110017992	TPR motif; other site
56110017993	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017994	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110017995	binding surface
56110017996	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110017997	TPR motif; other site
56110017998	CHAT domain; Region: CHAT; pfam12770
56110017999	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018000	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018001	binding surface
56110018002	TPR motif; other site
56110018003	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018004	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018005	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018006	binding surface
56110018007	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018008	TPR motif; other site
56110018009	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018010	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018011	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018012	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018013	binding surface
56110018014	TPR motif; other site
56110018015	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018016	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018017	binding surface
56110018018	TPR motif; other site
56110018019	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018020	CHAT domain; Region: CHAT; pfam12770
56110018021	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018022	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018023	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018024	binding surface
56110018025	TPR motif; other site
56110018026	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018027	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018028	binding surface
56110018029	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018030	TPR motif; other site
56110018031	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018032	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018033	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018034	binding surface
56110018035	TPR motif; other site
56110018036	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018037	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018038	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018039	TPR motif; other site
56110018040	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018041	binding surface
56110018042	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018043	CHAT domain; Region: CHAT; pfam12770
56110018044	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018045	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018046	binding surface
56110018047	TPR motif; other site
56110018048	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018049	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018050	binding surface
56110018051	TPR motif; other site
56110018052	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018053	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018054	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018055	binding surface
56110018056	TPR motif; other site
56110018057	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018058	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018059	binding surface
56110018060	TPR motif; other site
56110018061	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018062	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018063	binding surface
56110018064	TPR motif; other site
56110018065	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018066	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018067	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018068	binding surface
56110018069	TPR motif; other site
56110018070	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018071	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018072	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018073	binding surface
56110018074	TPR motif; other site
56110018075	CHAT domain; Region: CHAT; pfam12770
56110018076	Domain of Unknown Function (DUF928); Region: DUF928; pfam06051
56110018077	Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252
56110018078	CHASE2 domain; Region: CHASE2; pfam05226
56110018079	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110018080	cyclase homology domain; Region: CHD; cd07302
56110018081	nucleotidyl binding site; other site
56110018082	metal binding site [ion binding]; metal-binding site
56110018083	dimer interface [polypeptide binding]; other site
56110018084	HEAT repeats; Region: HEAT_2; pfam13646
56110018085	HEAT repeat; Region: HEAT; pfam02985
56110018086	HEAT repeats; Region: HEAT_2; pfam13646
56110018087	E-Z type HEAT repeats; Region: EZ_HEAT; smart00567
56110018088	HEAT repeats; Region: HEAT_2; pfam13646
56110018089	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110018090	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110018091	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110018092	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like; cd07473
56110018093	catalytic triad [active]
56110018094	putative active site [active]
56110018095	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110018096	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like; cd07473
56110018097	catalytic triad [active]
56110018098	putative active site [active]
56110018099	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
56110018100	Leishmanolysin; Region: Peptidase_M8; pfam01457
56110018101	DNA methylase; Region: N6_N4_Mtase; cl17433
56110018102	Methyltransferase domain; Region: Methyltransf_26; pfam13659
56110018103	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
56110018104	6-phosphofructokinase, eukaryotic type; Region: 6PF1K_euk; TIGR02478
56110018105	active site
56110018106	ADP/pyrophosphate binding site [chemical binding]; other site
56110018107	dimerization interface [polypeptide binding]; other site
56110018108	allosteric effector site; other site
56110018109	fructose-1,6-bisphosphate binding site; other site
56110018110	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110018111	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110018112	active site
56110018113	ATP binding site [chemical binding]; other site
56110018114	substrate binding site [chemical binding]; other site
56110018115	activation loop (A-loop); other site
56110018116	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
56110018117	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
56110018118	Uncharacterized conserved protein [Function unknown]; Region: COG1262
56110018119	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
56110018120	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110018121	putative active site [active]
56110018122	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110018123	putative active site [active]
56110018124	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2402
56110018125	putative active site [active]
56110018126	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
56110018127	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
56110018128	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110018129	active site
56110018130	ATP binding site [chemical binding]; other site
56110018131	substrate binding site [chemical binding]; other site
56110018132	activation loop (A-loop); other site
56110018133	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
56110018134	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
56110018135	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
56110018136	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110018137	SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from...; Region: XynB_like; cd01833
56110018138	active site
56110018139	catalytic triad [active]
56110018140	oxyanion hole [active]
56110018141	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
56110018142	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
56110018143	Domain of unknown function (DUF4278); Region: DUF4278; pfam14105
56110018144	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
56110018145	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
56110018146	catalytic residues [active]
56110018147	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110018148	active site
56110018149	phosphorylation site [posttranslational modification]
56110018150	intermolecular recognition site; other site
56110018151	PAS domain; Region: PAS; smart00091
56110018152	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110018153	putative active site [active]
56110018154	heme pocket [chemical binding]; other site
56110018155	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110018156	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110018157	putative active site [active]
56110018158	heme pocket [chemical binding]; other site
56110018159	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110018160	heme pocket [chemical binding]; other site
56110018161	putative active site [active]
56110018162	PAS domain; Region: PAS_9; pfam13426
56110018163	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110018164	PAS domain; Region: PAS_9; pfam13426
56110018165	putative active site [active]
56110018166	heme pocket [chemical binding]; other site
56110018167	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110018168	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110018169	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
56110018170	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110018171	dimer interface [polypeptide binding]; other site
56110018172	phosphorylation site [posttranslational modification]
56110018173	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110018174	ATP binding site [chemical binding]; other site
56110018175	Mg2+ binding site [ion binding]; other site
56110018176	G-X-G motif; other site
56110018177	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110018178	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110018179	active site
56110018180	phosphorylation site [posttranslational modification]
56110018181	intermolecular recognition site; other site
56110018182	dimerization interface [polypeptide binding]; other site
56110018183	type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521
56110018184	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018185	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
56110018186	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
56110018187	ATP binding site [chemical binding]; other site
56110018188	putative Mg++ binding site [ion binding]; other site
56110018189	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
56110018190	nucleotide binding region [chemical binding]; other site
56110018191	ATP-binding site [chemical binding]; other site
56110018192	GTPase Era; Reviewed; Region: era; PRK00089
56110018193	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
56110018194	G1 box; other site
56110018195	GTP/Mg2+ binding site [chemical binding]; other site
56110018196	Switch I region; other site
56110018197	G2 box; other site
56110018198	Switch II region; other site
56110018199	G3 box; other site
56110018200	G4 box; other site
56110018201	KH domain; Region: KH_2; pfam07650
56110018202	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110018203	putative active site [active]
56110018204	Uncharacterized protein family (UPF0231); Region: UPF0231; cl11474
56110018205	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
56110018206	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
56110018207	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
56110018208	PAS domain S-box; Region: sensory_box; TIGR00229
56110018209	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110018210	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110018211	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
56110018212	putative active site [active]
56110018213	heme pocket [chemical binding]; other site
56110018214	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
56110018215	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110018216	putative active site [active]
56110018217	heme pocket [chemical binding]; other site
56110018218	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110018219	dimer interface [polypeptide binding]; other site
56110018220	phosphorylation site [posttranslational modification]
56110018221	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110018222	ATP binding site [chemical binding]; other site
56110018223	Mg2+ binding site [ion binding]; other site
56110018224	G-X-G motif; other site
56110018225	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
56110018226	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110018227	active site
56110018228	phosphorylation site [posttranslational modification]
56110018229	intermolecular recognition site; other site
56110018230	dimerization interface [polypeptide binding]; other site
56110018231	Response regulator receiver domain; Region: Response_reg; pfam00072
56110018232	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110018233	active site
56110018234	phosphorylation site [posttranslational modification]
56110018235	intermolecular recognition site; other site
56110018236	dimerization interface [polypeptide binding]; other site
56110018237	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110018238	dimer interface [polypeptide binding]; other site
56110018239	phosphorylation site [posttranslational modification]
56110018240	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110018241	ATP binding site [chemical binding]; other site
56110018242	Mg2+ binding site [ion binding]; other site
56110018243	G-X-G motif; other site
56110018244	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
56110018245	peripheral dimer interface [polypeptide binding]; other site
56110018246	core dimer interface [polypeptide binding]; other site
56110018247	L10 interface [polypeptide binding]; other site
56110018248	L11 interface [polypeptide binding]; other site
56110018249	putative EF-Tu interaction site [polypeptide binding]; other site
56110018250	putative EF-G interaction site [polypeptide binding]; other site
56110018251	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
56110018252	23S rRNA interface [nucleotide binding]; other site
56110018253	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
56110018254	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
56110018255	mRNA/rRNA interface [nucleotide binding]; other site
56110018256	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
56110018257	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
56110018258	23S rRNA interface [nucleotide binding]; other site
56110018259	L7/L12 interface [polypeptide binding]; other site
56110018260	putative thiostrepton binding site; other site
56110018261	L25 interface [polypeptide binding]; other site
56110018262	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
56110018263	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
56110018264	putative homodimer interface [polypeptide binding]; other site
56110018265	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
56110018266	heterodimer interface [polypeptide binding]; other site
56110018267	homodimer interface [polypeptide binding]; other site
56110018268	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
56110018269	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
56110018270	deoxyhypusine synthase-like protein; Provisional; Region: PRK00770
56110018271	deoxyhypusine synthase; Region: dhys; TIGR00321
56110018272	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
56110018273	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
56110018274	putative dimer interface [polypeptide binding]; other site
56110018275	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
56110018276	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
56110018277	nucleotide binding site [chemical binding]; other site
56110018278	NEF interaction site [polypeptide binding]; other site
56110018279	SBD interface [polypeptide binding]; other site
56110018280	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110018281	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018282	TPR repeat; Region: TPR_11; pfam13414
56110018283	binding surface
56110018284	TPR motif; other site
56110018285	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110018286	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110018287	Circadian oscillating protein COP23; Region: COP23; pfam14218
56110018288	ParB-like nuclease domain; Region: ParBc; pfam02195
56110018289	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
56110018290	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
56110018291	Catalytic site [active]
56110018292	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110018293	active site
56110018294	NTP binding site [chemical binding]; other site
56110018295	metal binding triad [ion binding]; metal-binding site
56110018296	antibiotic binding site [chemical binding]; other site
56110018297	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
56110018298	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
56110018299	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
56110018300	trimer interface [polypeptide binding]; other site
56110018301	active site
56110018302	substrate binding site [chemical binding]; other site
56110018303	CoA binding site [chemical binding]; other site
56110018304	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
56110018305	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
56110018306	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110018307	dimer interface [polypeptide binding]; other site
56110018308	conserved gate region; other site
56110018309	putative PBP binding loops; other site
56110018310	ABC-ATPase subunit interface; other site
56110018311	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
56110018312	Domain of unknown function DUF20; Region: UPF0118; pfam01594
56110018313	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
56110018314	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
56110018315	HlyD family secretion protein; Region: HlyD_3; pfam13437
56110018316	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
56110018317	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
56110018318	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
56110018319	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
56110018320	putative active site [active]
56110018321	putative NTP binding site [chemical binding]; other site
56110018322	putative nucleic acid binding site [nucleotide binding]; other site
56110018323	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
56110018324	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110018325	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110018326	active site
56110018327	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
56110018328	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110018329	putative active site [active]
56110018330	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110018331	putative active site [active]
56110018332	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110018333	putative active site [active]
56110018334	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110018335	NACHT domain; Region: NACHT; pfam05729
56110018336	Walker A motif; other site
56110018337	ATP binding site [chemical binding]; other site
56110018338	Walker B motif; other site
56110018339	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
56110018340	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
56110018341	protein binding surface [polypeptide binding]; other site
56110018342	Homeodomain-like domain; Region: HTH_23; pfam13384
56110018343	Winged helix-turn helix; Region: HTH_29; pfam13551
56110018344	Winged helix-turn helix; Region: HTH_33; pfam13592
56110018345	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110018346	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110018347	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
56110018348	putative active site [active]
56110018349	photosystem I P700 chlorophyll a apoprotein A1; Region: psaA; CHL00056
56110018350	photosystem I P700 chlorophyll a apoprotein A2; Provisional; Region: psaB; PRK13199
56110018351	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
56110018352	non-specific DNA binding site [nucleotide binding]; other site
56110018353	salt bridge; other site
56110018354	sequence-specific DNA binding site [nucleotide binding]; other site
56110018355	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
56110018356	active site
56110018357	catalytic triad [active]
56110018358	oxyanion hole [active]
56110018359	Protein of unknown function (DUF433); Region: DUF433; pfam04255
56110018360	Protein of unknown function (DUF2281); Region: DUF2281; cl02355
56110018361	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018362	TPR motif; other site
56110018363	binding surface
56110018364	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018365	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018366	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018367	TPR motif; other site
56110018368	binding surface
56110018369	CHAT domain; Region: CHAT; pfam12770
56110018370	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
56110018371	oligomeric interface; other site
56110018372	putative active site [active]
56110018373	homodimer interface [polypeptide binding]; other site
56110018374	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
56110018375	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
56110018376	Coenzyme A binding pocket [chemical binding]; other site
56110018377	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110018378	This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802
56110018379	putative ADP-binding pocket [chemical binding]; other site
56110018380	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell envelope biogenesis, outer membrane]; Region: PbpC; COG4953
56110018381	Transglycosylase; Region: Transgly; pfam00912
56110018382	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
56110018383	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
56110018384	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
56110018385	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110018386	active site
56110018387	phosphorylation site [posttranslational modification]
56110018388	intermolecular recognition site; other site
56110018389	dimerization interface [polypeptide binding]; other site
56110018390	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
56110018391	dimer interface [polypeptide binding]; other site
56110018392	phosphorylation site [posttranslational modification]
56110018393	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
56110018394	ATP binding site [chemical binding]; other site
56110018395	Mg2+ binding site [ion binding]; other site
56110018396	G-X-G motif; other site
56110018397	Response regulator receiver domain; Region: Response_reg; pfam00072
56110018398	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
56110018399	active site
56110018400	phosphorylation site [posttranslational modification]
56110018401	intermolecular recognition site; other site
56110018402	dimerization interface [polypeptide binding]; other site
56110018403	glycogen synthase; Provisional; Region: glgA; PRK00654
56110018404	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
56110018405	ADP-binding pocket [chemical binding]; other site
56110018406	homodimer interface [polypeptide binding]; other site
56110018407	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
56110018408	active site
56110018409	NTP binding site [chemical binding]; other site
56110018410	metal binding triad [ion binding]; metal-binding site
56110018411	antibiotic binding site [chemical binding]; other site
56110018412	Protein of unknown function DUF86; Region: DUF86; pfam01934
56110018413	WYL domain; Region: WYL; pfam13280
56110018414	CRISPR/Cas system-associated protein Csc2; Region: Csc2_I-D; cl11869
56110018415	CRISPR/Cas system-associated protein Csc1; Region: Csc1_I-D; cd09711
56110018416	CRISPR type I-D/CYANO-associated protein Csc1; Region: cas_Csc1; TIGR03159
56110018417	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
56110018418	CRISPR-associated helicase Cas3, subtype CYANO; Region: cas3_cyano; TIGR03158
56110018419	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cl11443
56110018420	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
56110018421	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cd09637
56110018422	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cd09634
56110018423	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
56110018424	Predicted membrane protein [Function unknown]; Region: COG4244
56110018425	Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3670
56110018426	Retinal pigment epithelial membrane protein; Region: RPE65; pfam03055
56110018427	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110018428	Major Facilitator Superfamily; Region: MFS_1; pfam07690
56110018429	putative substrate translocation pore; other site
56110018430	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
56110018431	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
56110018432	active site
56110018433	substrate binding site [chemical binding]; other site
56110018434	Mg2+ binding site [ion binding]; other site
56110018435	Nuclease A inhibitor-like protein; Region: NuiA; pfam07924
56110018436	Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170
56110018437	nucleotide binding site [chemical binding]; other site
56110018438	putative NEF/HSP70 interaction site [polypeptide binding]; other site
56110018439	SBD interface [polypeptide binding]; other site
56110018440	Fibrinogen alpha/beta chain family; Region: Fib_alpha; pfam08702
56110018441	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018442	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110018443	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018444	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018445	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110018446	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018447	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018448	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018449	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
56110018450	Catalytic domain of Protein Kinases; Region: PKc; cd00180
56110018451	active site
56110018452	ATP binding site [chemical binding]; other site
56110018453	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
56110018454	substrate binding site [chemical binding]; other site
56110018455	activation loop (A-loop); other site
56110018456	phosphoenolpyruvate synthase; Validated; Region: PRK06464
56110018457	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
56110018458	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
56110018459	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
56110018460	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
56110018461	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; pfam02571
56110018462	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
56110018463	active site
56110018464	putative homodimer interface [polypeptide binding]; other site
56110018465	SAM binding site [chemical binding]; other site
56110018466	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
56110018467	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110018468	S-adenosylmethionine binding site [chemical binding]; other site
56110018469	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
56110018470	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
56110018471	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
56110018472	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
56110018473	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
56110018474	precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285
56110018475	Precorrin-8X methylmutase; Region: CbiC; pfam02570
56110018476	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
56110018477	active site
56110018478	SAM binding site [chemical binding]; other site
56110018479	homodimer interface [polypeptide binding]; other site
56110018480	Cobalamin biosynthesis protein CbiG [Coenzyme metabolism]; Region: CbiG; COG2073
56110018481	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
56110018482	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
56110018483	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
56110018484	active site
56110018485	SAM binding site [chemical binding]; other site
56110018486	homodimer interface [polypeptide binding]; other site
56110018487	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
56110018488	nicotinamide-nucleotide adenylyltransferase, NadR type; Region: nadR_NMN_Atrans; TIGR01526
56110018489	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
56110018490	active site
56110018491	nucleotide binding site [chemical binding]; other site
56110018492	HIGH motif; other site
56110018493	KMSKS motif; other site
56110018494	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
56110018495	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
56110018496	Fatty acid desaturase; Region: FA_desaturase; pfam00487
56110018497	Di-iron ligands [ion binding]; other site
56110018498	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
56110018499	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
56110018500	FeS/SAM binding site; other site
56110018501	HemN C-terminal domain; Region: HemN_C; pfam06969
56110018502	Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; Region: HemeO; cd00232
56110018503	heme binding pocket [chemical binding]; other site
56110018504	heme ligand [chemical binding]; other site
56110018505	Aerobic Cyclase System Fe-containing subunit (ACSF), ferritin-like diiron-binding domain; Region: ACSF; cd01047
56110018506	diiron binding motif [ion binding]; other site
56110018507	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
56110018508	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110018509	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018510	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018511	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018512	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018513	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
56110018514	active site residue [active]
56110018515	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
56110018516	Predicted membrane protein (DUF2214); Region: DUF2214; pfam09980
56110018517	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
56110018518	cytochrome b6-f complex iron-sulfur subunit; Provisional; Region: PRK13474
56110018519	Cytochrome B6-F complex Fe-S subunit; Region: CytB6-F_Fe-S; pfam08802
56110018520	Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The cytochrome b6f complex from Mastigocladus laminosus, a thermophilic cyanobacterium; Region: Rieske_cytochrome_b6f; cd03471
56110018521	cytochrome b subunit interaction site [polypeptide binding]; other site
56110018522	[2Fe-2S] cluster binding site [ion binding]; other site
56110018523	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
56110018524	Uncharacterized family of ferritin-like proteins found in archaea and bacteria; Region: Ferritin_like_AB2; cd01048
56110018525	diiron binding motif [ion binding]; other site
56110018526	Heterodisulfide reductase, subunit B [Energy production and conversion]; Region: HdrB; COG2048
56110018527	Cysteine-rich domain; Region: CCG; pfam02754
56110018528	Cysteine-rich domain; Region: CCG; pfam02754
56110018529	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
56110018530	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
56110018531	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
56110018532	Heterodisulfide reductase, subunit B [Energy production and conversion]; Region: HdrB; COG2048
56110018533	Cysteine-rich domain; Region: CCG; pfam02754
56110018534	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
56110018535	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
56110018536	active site residue [active]
56110018537	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
56110018538	D1, D2 subunits of photosystem II  (PSII); M, L subunits of bacterial photosynthetic reaction center; Region: Photo_RC; cl08220
56110018539	pheophytin binding site; other site
56110018540	chlorophyll binding site; other site
56110018541	quinone binding site; other site
56110018542	Fe binding site [ion binding]; other site
56110018543	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
56110018544	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
56110018545	Homeodomain-like domain; Region: HTH_23; pfam13384
56110018546	Winged helix-turn helix; Region: HTH_29; pfam13551
56110018547	Homeodomain-like domain; Region: HTH_32; pfam13565
56110018548	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110018549	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110018550	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
56110018551	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
56110018552	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
56110018553	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
56110018554	Uncharacterized conserved protein [Function unknown]; Region: COG1262
56110018555	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
56110018556	active site clefts [active]
56110018557	zinc binding site [ion binding]; other site
56110018558	dimer interface [polypeptide binding]; other site
56110018559	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
56110018560	dimerization interface [polypeptide binding]; other site
56110018561	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
56110018562	ATP binding site [chemical binding]; other site
56110018563	bidirectional hydrogenase complex protein HoxE; Reviewed; Region: PRK07571
56110018564	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
56110018565	putative dimer interface [polypeptide binding]; other site
56110018566	[2Fe-2S] cluster binding site [ion binding]; other site
56110018567	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
56110018568	dimer interface [polypeptide binding]; other site
56110018569	[2Fe-2S] cluster binding site [ion binding]; other site
56110018570	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
56110018571	SLBB domain; Region: SLBB; pfam10531
56110018572	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
56110018573	bidirectional hydrogenase complex protein HoxU; Validated; Region: PRK07569
56110018574	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110018575	catalytic loop [active]
56110018576	iron binding site [ion binding]; other site
56110018577	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
56110018578	4Fe-4S binding domain; Region: Fer4; pfam00037
56110018579	Coenzyme F420-reducing hydrogenase, gamma subunit [Energy production and conversion]; Region: FrhG; COG1941
56110018580	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
56110018581	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
56110018582	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
56110018583	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
56110018584	dimer interface [polypeptide binding]; other site
56110018585	[2Fe-2S] cluster binding site [ion binding]; other site
56110018586	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
56110018587	PAS domain; Region: PAS_9; pfam13426
56110018588	putative active site [active]
56110018589	heme pocket [chemical binding]; other site
56110018590	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
56110018591	Endopeptidases that belong to the bidirectional NAD-linked hydrogenase group. This group of endopeptidases are highly specific carboxyl-terminal protease (HoxW protease) which releases a 24-amino-acid peptide from HoxH prior to progression of subunit...; Region: H2MP_NAD-link-bidir; cd06066
56110018592	nickel binding site [ion binding]; other site
56110018593	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
56110018594	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
56110018595	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
56110018596	Acylphosphatase; Region: Acylphosphatase; pfam00708
56110018597	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
56110018598	HypF finger; Region: zf-HYPF; pfam07503
56110018599	HypF finger; Region: zf-HYPF; pfam07503
56110018600	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
56110018601	HupF/HypC family; Region: HupF_HypC; pfam01455
56110018602	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
56110018603	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
56110018604	dimer interface [polypeptide binding]; other site
56110018605	PYR/PP interface [polypeptide binding]; other site
56110018606	TPP binding site [chemical binding]; other site
56110018607	substrate binding site [chemical binding]; other site
56110018608	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
56110018609	Domain of unknown function; Region: EKR; pfam10371
56110018610	4Fe-4S binding domain; Region: Fer4_6; pfam12837
56110018611	4Fe-4S binding domain; Region: Fer4; pfam00037
56110018612	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
56110018613	TPP-binding site [chemical binding]; other site
56110018614	dimer interface [polypeptide binding]; other site
56110018615	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK07565
56110018616	Dihydroorotate dehydrogenase (DHOD) like proteins. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD...; Region: DHOD_like; cd04739
56110018617	putative active site [active]
56110018618	putative FMN binding site [chemical binding]; other site
56110018619	putative substrate binding site [chemical binding]; other site
56110018620	DNA-directed RNA polymerase subunit beta'; Provisional; Region: rpoC2; PRK02597
56110018621	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
56110018622	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
56110018623	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
56110018624	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
56110018625	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
56110018626	Apocytochrome F, C-terminal; Region: Apocytochr_F_C; cl03168
56110018627	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
56110018628	DNA binding site [nucleotide binding]
56110018629	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
56110018630	DNA-directed RNA polymerase subunit gamma; Provisional; Region: rpoC1; PRK02625
56110018631	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
56110018632	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
56110018633	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
56110018634	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
56110018635	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
56110018636	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
56110018637	RPB1 interaction site [polypeptide binding]; other site
56110018638	RPB10 interaction site [polypeptide binding]; other site
56110018639	RPB11 interaction site [polypeptide binding]; other site
56110018640	RPB3 interaction site [polypeptide binding]; other site
56110018641	RPB12 interaction site [polypeptide binding]; other site
56110018642	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
56110018643	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
56110018644	active site
56110018645	ribosomal protein S20; Region: rps20; CHL00102
56110018646	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
56110018647	histidinol dehydrogenase; Region: hisD; TIGR00069
56110018648	NAD binding site [chemical binding]; other site
56110018649	dimerization interface [polypeptide binding]; other site
56110018650	product binding site; other site
56110018651	substrate binding site [chemical binding]; other site
56110018652	zinc binding site [ion binding]; other site
56110018653	catalytic residues [active]
56110018654	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110018655	Ligand Binding Site [chemical binding]; other site
56110018656	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
56110018657	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
56110018658	Protein of unknown function (DUF721); Region: DUF721; pfam05258
56110018659	NlpC/P60 family; Region: NLPC_P60; cl17555
56110018660	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
56110018661	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
56110018662	substrate binding site [chemical binding]; other site
56110018663	oxyanion hole (OAH) forming residues; other site
56110018664	trimer interface [polypeptide binding]; other site
56110018665	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
56110018666	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
56110018667	metal ion-dependent adhesion site (MIDAS); other site
56110018668	Beta-lactamase class A [Defense mechanisms]; Region: PenP; COG2367
56110018669	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
56110018670	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
56110018671	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
56110018672	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
56110018673	MutS domain I; Region: MutS_I; pfam01624
56110018674	MutS domain II; Region: MutS_II; pfam05188
56110018675	MutS domain III; Region: MutS_III; pfam05192
56110018676	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
56110018677	Walker A/P-loop; other site
56110018678	ATP binding site [chemical binding]; other site
56110018679	Q-loop/lid; other site
56110018680	ABC transporter signature motif; other site
56110018681	Walker B; other site
56110018682	D-loop; other site
56110018683	H-loop/switch region; other site
56110018684	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
56110018685	putative active site [active]
56110018686	putative metal binding site [ion binding]; other site
56110018687	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
56110018688	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
56110018689	AAA domain; Region: AAA_33; pfam13671
56110018690	ATP-binding site [chemical binding]; other site
56110018691	Gluconate-6-phosphate binding site [chemical binding]; other site
56110018692	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110018693	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1672
56110018694	Protein of unknown function, DUF258; Region: DUF258; pfam03193
56110018695	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110018696	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110018697	structural tetrad; other site
56110018698	CpeT/CpcT family (DUF1001); Region: CpeT; pfam06206
56110018699	UDP_sulfoquinovose_synthase (Arabidopsis thaliana SQD1 and related proteins), extended (e) SDRs; Region: SQD1_like_SDR_e; cd05255
56110018700	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
56110018701	NAD binding site [chemical binding]; other site
56110018702	substrate binding site [chemical binding]; other site
56110018703	active site
56110018704	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110018705	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
56110018706	RRXRR protein; Region: RRXRR; pfam14239
56110018707	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
56110018708	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
56110018709	active site
56110018710	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110018711	GAF domain; Region: GAF_2; pfam13185
56110018712	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
56110018713	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
56110018714	PAS domain; Region: PAS; smart00091
56110018715	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
56110018716	cyclase homology domain; Region: CHD; cd07302
56110018717	nucleotidyl binding site; other site
56110018718	metal binding site [ion binding]; metal-binding site
56110018719	dimer interface [polypeptide binding]; other site
56110018720	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110018721	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018722	HEAT repeats; Region: HEAT_2; pfam13646
56110018723	Protein of unknown function (DUF433); Region: DUF433; pfam04255
56110018724	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
56110018725	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
56110018726	dimer interface [polypeptide binding]; other site
56110018727	conserved gate region; other site
56110018728	putative PBP binding loops; other site
56110018729	ABC-ATPase subunit interface; other site
56110018730	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
56110018731	active site
56110018732	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
56110018733	classical (c) SDRs; Region: SDR_c; cd05233
56110018734	NAD(P) binding site [chemical binding]; other site
56110018735	active site
56110018736	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
56110018737	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
56110018738	Walker A/P-loop; other site
56110018739	ATP binding site [chemical binding]; other site
56110018740	Q-loop/lid; other site
56110018741	ABC transporter signature motif; other site
56110018742	Walker B; other site
56110018743	D-loop; other site
56110018744	H-loop/switch region; other site
56110018745	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
56110018746	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_37; cd04696
56110018747	nudix motif; other site
56110018748	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110018749	Dihydroneopterin aldolase; Region: FolB; pfam02152
56110018750	active site
56110018751	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
56110018752	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
56110018753	ATP binding site [chemical binding]; other site
56110018754	active site
56110018755	substrate binding site [chemical binding]; other site
56110018756	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
56110018757	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
56110018758	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
56110018759	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
56110018760	Surface antigen; Region: Bac_surface_Ag; pfam01103
56110018761	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
56110018762	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
56110018763	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
56110018764	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
56110018765	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
56110018766	active site
56110018767	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
56110018768	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
56110018769	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
56110018770	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
56110018771	ligand binding site [chemical binding]; other site
56110018772	flexible hinge region; other site
56110018773	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
56110018774	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
56110018775	Walker A motif; other site
56110018776	ATP binding site [chemical binding]; other site
56110018777	Walker B motif; other site
56110018778	Polyferredoxin [Energy production and conversion]; Region: NapH; COG0348
56110018779	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
56110018780	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
56110018781	dimer interface [polypeptide binding]; other site
56110018782	pyridoxal 5'-phosphate binding site [chemical binding]; other site
56110018783	catalytic residue [active]
56110018784	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
56110018785	ABC1 family; Region: ABC1; cl17513
56110018786	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
56110018787	active site
56110018788	Phycobilisome degradation protein nblA; Region: NblA; pfam04485
56110018789	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110018790	Ligand Binding Site [chemical binding]; other site
56110018791	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
56110018792	Ligand Binding Site [chemical binding]; other site
56110018793	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
56110018794	RNA/DNA hybrid binding site [nucleotide binding]; other site
56110018795	active site
56110018796	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
56110018797	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
56110018798	motif II; other site
56110018799	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
56110018800	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
56110018801	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
56110018802	catalytic site [active]
56110018803	active site
56110018804	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
56110018805	maltooligosyl trehalose synthase; Provisional; Region: PRK14511
56110018806	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
56110018807	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
56110018808	active site
56110018809	catalytic site [active]
56110018810	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
56110018811	Trehalase; Region: Trehalase; cl17346
56110018812	Domain of unknown function (DUF4342); Region: DUF4342; pfam14242
56110018813	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
56110018814	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
56110018815	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
56110018816	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
56110018817	ferredoxin-nitrite reductase; Reviewed; Region: nirA; PRK09566
56110018818	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
56110018819	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
56110018820	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
56110018821	catalytic loop [active]
56110018822	iron binding site [ion binding]; other site
56110018823	nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886
56110018824	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110018825	putative substrate translocation pore; other site
56110018826	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
56110018827	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
56110018828	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
56110018829	[4Fe-4S] binding site [ion binding]; other site
56110018830	molybdopterin cofactor binding site; other site
56110018831	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
56110018832	molybdopterin cofactor binding site; other site
56110018833	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
56110018834	putative active site [active]
56110018835	Peptidase_C39 like family; Region: Peptidase_C39_2; pfam13529
56110018836	putative active site [active]
56110018837	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
56110018838	catalytic core [active]
56110018839	glucokinase; Provisional; Region: glk; PRK00292
56110018840	glucokinase, proteobacterial type; Region: glk; TIGR00749
56110018841	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
56110018842	active site
56110018843	catalytic residues [active]
56110018844	metal binding site [ion binding]; metal-binding site
56110018845	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
56110018846	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
56110018847	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
56110018848	protein binding site [polypeptide binding]; other site
56110018849	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
56110018850	active site
56110018851	catalytic residues [active]
56110018852	DNA binding site [nucleotide binding]
56110018853	Int/Topo IB signature motif; other site
56110018854	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
56110018855	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
56110018856	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
56110018857	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
56110018858	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110018859	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
56110018860	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
56110018861	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
56110018862	Mg binding site [ion binding]; other site
56110018863	nucleotide binding site [chemical binding]; other site
56110018864	putative protofilament interface [polypeptide binding]; other site
56110018865	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
56110018866	non-specific DNA binding site [nucleotide binding]; other site
56110018867	salt bridge; other site
56110018868	sequence-specific DNA binding site [nucleotide binding]; other site
56110018869	D5 N terminal like; Region: D5_N; pfam08706
56110018870	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
56110018871	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110018872	Walker A/P-loop; other site
56110018873	ATP binding site [chemical binding]; other site
56110018874	ABC transporter signature motif; other site
56110018875	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110018876	Homeodomain-like domain; Region: HTH_23; pfam13384
56110018877	Winged helix-turn helix; Region: HTH_29; pfam13551
56110018878	Homeodomain-like domain; Region: HTH_32; pfam13565
56110018879	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110018880	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
56110018881	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110018882	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
56110018883	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
56110018884	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
56110018885	active site
56110018886	substrate binding site [chemical binding]; other site
56110018887	Mg2+ binding site [ion binding]; other site
56110018888	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018889	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018890	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
56110018891	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018892	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110018893	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018894	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018895	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018896	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018897	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
56110018898	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
56110018899	active site
56110018900	substrate binding site [chemical binding]; other site
56110018901	Mg2+ binding site [ion binding]; other site
56110018902	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018903	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
56110018904	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018905	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018906	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018907	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018908	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018909	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
56110018910	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
56110018911	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
56110018912	catalytic residues [active]
56110018913	catalytic nucleophile [active]
56110018914	Recombinase; Region: Recombinase; pfam07508
56110018915	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
56110018916	Chondroitin sulphate attachment domain; Region: Chon_Sulph_att; pfam06566
56110018917	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
56110018918	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110018919	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
56110018920	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
56110018921	active site
56110018922	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018923	TPR motif; other site
56110018924	TPR repeat; Region: TPR_11; pfam13414
56110018925	binding surface
56110018926	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018927	binding surface
56110018928	TPR repeat; Region: TPR_11; pfam13414
56110018929	TPR motif; other site
56110018930	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018931	binding surface
56110018932	TPR motif; other site
56110018933	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
56110018934	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018935	binding surface
56110018936	TPR motif; other site
56110018937	TPR repeat; Region: TPR_11; pfam13414
56110018938	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018939	binding surface
56110018940	TPR motif; other site
56110018941	TPR repeat; Region: TPR_11; pfam13414
56110018942	TPR repeat; Region: TPR_11; pfam13414
56110018943	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018944	binding surface
56110018945	TPR motif; other site
56110018946	TPR repeat; Region: TPR_11; pfam13414
56110018947	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018948	TPR motif; other site
56110018949	binding surface
56110018950	TPR repeat; Region: TPR_11; pfam13414
56110018951	Protein of unknown function (DUF563); Region: DUF563; pfam04577
56110018952	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018953	binding surface
56110018954	TPR motif; other site
56110018955	TPR repeat; Region: TPR_11; pfam13414
56110018956	TPR repeat; Region: TPR_11; pfam13414
56110018957	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018958	binding surface
56110018959	TPR motif; other site
56110018960	TPR repeat; Region: TPR_11; pfam13414
56110018961	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018962	binding surface
56110018963	TPR motif; other site
56110018964	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
56110018965	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018966	binding surface
56110018967	TPR motif; other site
56110018968	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018969	binding surface
56110018970	TPR motif; other site
56110018971	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018972	binding surface
56110018973	TPR motif; other site
56110018974	TPR repeat; Region: TPR_11; pfam13414
56110018975	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018976	binding surface
56110018977	Tetratricopeptide repeat; Region: TPR_16; pfam13432
56110018978	TPR motif; other site
56110018979	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110018980	TPR repeat; Region: TPR_11; pfam13414
56110018981	binding surface
56110018982	TPR motif; other site
56110018983	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
56110018984	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
56110018985	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
56110018986	P-loop; other site
56110018987	Magnesium ion binding site [ion binding]; other site
56110018988	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
56110018989	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
56110018990	catalytic residues [active]
56110018991	catalytic nucleophile [active]
56110018992	Recombinase; Region: Recombinase; pfam07508
56110018993	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
56110018994	Transposase domain (DUF772); Region: DUF772; pfam05598
56110018995	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
56110018996	Peptidase family M23; Region: Peptidase_M23; pfam01551
56110018997	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
56110018998	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
56110018999	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
56110019000	Mg binding site [ion binding]; other site
56110019001	nucleotide binding site [chemical binding]; other site
56110019002	putative protofilament interface [polypeptide binding]; other site
56110019003	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
56110019004	non-specific DNA binding site [nucleotide binding]; other site
56110019005	salt bridge; other site
56110019006	sequence-specific DNA binding site [nucleotide binding]; other site
56110019007	D5 N terminal like; Region: D5_N; pfam08706
56110019008	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
56110019009	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
56110019010	Walker A/P-loop; other site
56110019011	ATP binding site [chemical binding]; other site
56110019012	ABC transporter signature motif; other site
56110019013	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
56110019014	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
56110019015	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
56110019016	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110019017	WD40 repeats; Region: WD40; smart00320
56110019018	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110019019	structural tetrad; other site
56110019020	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110019021	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110019022	structural tetrad; other site
56110019023	FOG: WD40 repeat [General function prediction only]; Region: COG2319
56110019024	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110019025	structural tetrad; other site
56110019026	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
56110019027	structural tetrad; other site
56110019028	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110019029	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110019030	binding surface
56110019031	TPR motif; other site
56110019032	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110019033	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
56110019034	binding surface
56110019035	TPR motif; other site
56110019036	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110019037	Tetratricopeptide repeat; Region: TPR_12; pfam13424
56110019038	CHAT domain; Region: CHAT; pfam12770
56110019039	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
56110019040	active site
56110019041	catalytic residues [active]
56110019042	DNA binding site [nucleotide binding]
56110019043	Int/Topo IB signature motif; other site
56110019044	Prophage antirepressor [Transcription]; Region: COG3617
56110019045	BRO family, N-terminal domain; Region: Bro-N; smart01040
56110019046	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
56110019047	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
56110019048	active site
56110019049	acyl-CoA synthetase; Validated; Region: PRK05850
56110019050	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
56110019051	acyl-activating enzyme (AAE) consensus motif; other site
56110019052	active site
56110019053	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
56110019054	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
56110019055	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
56110019056	PIN domain; Region: PIN_3; pfam13470
56110019057	HicB family; Region: HicB; pfam05534
56110019058	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
56110019059	Protein of unknown function (DUF2281); Region: DUF2281; cl02355
56110019060	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2402
56110019061	putative active site [active]
56110019062	Rhodopirellula transposase DDE domain; Region: DDE_Tnp_ISAZ013; pfam07592
56110019063	DDE superfamily endonuclease; Region: DDE_3; pfam13358
56110019064	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
56110019065	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
56110019066	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
56110019067	S-adenosylmethionine binding site [chemical binding]; other site
56110019068	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; COG0382
56110019069	UbiA prenyltransferase family; Region: UbiA; pfam01040
56110019070	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
56110019071	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
56110019072	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438