-- dump date   	20140619_225702
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1429244000001	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1429244000002	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1429244000003	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1429244000004	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244000005	Walker A motif; other site
1429244000006	ATP binding site [chemical binding]; other site
1429244000007	Walker B motif; other site
1429244000008	arginine finger; other site
1429244000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1429244000010	DnaA box-binding interface [nucleotide binding]; other site
1429244000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1429244000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1429244000013	putative DNA binding surface [nucleotide binding]; other site
1429244000014	dimer interface [polypeptide binding]; other site
1429244000015	beta-clamp/clamp loader binding surface; other site
1429244000016	beta-clamp/translesion DNA polymerase binding surface; other site
1429244000017	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244000018	RNA binding surface [nucleotide binding]; other site
1429244000019	recombination protein F; Reviewed; Region: recF; PRK00064
1429244000020	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
1429244000021	Walker A/P-loop; other site
1429244000022	ATP binding site [chemical binding]; other site
1429244000023	Q-loop/lid; other site
1429244000024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244000025	ABC transporter signature motif; other site
1429244000026	Walker B; other site
1429244000027	D-loop; other site
1429244000028	H-loop/switch region; other site
1429244000029	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1429244000030	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244000031	Mg2+ binding site [ion binding]; other site
1429244000032	G-X-G motif; other site
1429244000033	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1429244000034	anchoring element; other site
1429244000035	dimer interface [polypeptide binding]; other site
1429244000036	ATP binding site [chemical binding]; other site
1429244000037	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1429244000038	active site
1429244000039	putative metal-binding site [ion binding]; other site
1429244000040	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1429244000041	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244000042	DNA gyrase subunit A; Validated; Region: PRK05560
1429244000043	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1429244000044	CAP-like domain; other site
1429244000045	active site
1429244000046	primary dimer interface [polypeptide binding]; other site
1429244000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244000050	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244000051	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244000052	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244000053	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1429244000054	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244000055	Zn2+ binding site [ion binding]; other site
1429244000056	Mg2+ binding site [ion binding]; other site
1429244000057	Inhibitor of sigma-G Gin; Region: Gin; pfam10764
1429244000058	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1429244000059	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244000060	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244000061	catalytic residue [active]
1429244000062	thymidylate kinase; Validated; Region: tmk; PRK00698
1429244000063	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1429244000064	TMP-binding site; other site
1429244000065	ATP-binding site [chemical binding]; other site
1429244000066	Protein of unknown function (DUF970); Region: DUF970; pfam06153
1429244000067	Protein of unknown function (DUF327); Region: DUF327; pfam03885
1429244000068	DNA polymerase III subunit delta'; Validated; Region: PRK08058
1429244000069	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1429244000070	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
1429244000071	DNA replication intiation control protein YabA; Reviewed; Region: PRK13169
1429244000072	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1429244000073	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244000074	S-adenosylmethionine binding site [chemical binding]; other site
1429244000075	Predicted methyltransferases [General function prediction only]; Region: COG0313
1429244000076	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1429244000077	putative SAM binding site [chemical binding]; other site
1429244000078	putative homodimer interface [polypeptide binding]; other site
1429244000079	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1429244000080	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
1429244000081	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244000082	Zn2+ binding site [ion binding]; other site
1429244000083	Mg2+ binding site [ion binding]; other site
1429244000084	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1429244000085	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1429244000086	active site
1429244000087	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1429244000088	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1429244000089	G5 domain; Region: G5; pfam07501
1429244000090	3D domain; Region: 3D; cl01439
1429244000091	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
1429244000092	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
1429244000093	putative active site [active]
1429244000094	putative metal binding site [ion binding]; other site
1429244000095	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
1429244000096	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1429244000097	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244000098	S-adenosylmethionine binding site [chemical binding]; other site
1429244000099	YabG peptidase U57; Region: Peptidase_U57; cl05250
1429244000100	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
1429244000101	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1429244000102	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
1429244000103	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1429244000104	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1429244000105	pur operon repressor; Provisional; Region: PRK09213
1429244000106	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
1429244000107	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244000108	active site
1429244000109	regulatory protein SpoVG; Reviewed; Region: PRK13259
1429244000110	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
1429244000111	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1429244000112	Substrate binding site; other site
1429244000113	Mg++ binding site; other site
1429244000114	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1429244000115	active site
1429244000116	substrate binding site [chemical binding]; other site
1429244000117	CoA binding site [chemical binding]; other site
1429244000118	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1429244000119	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1429244000120	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244000121	active site
1429244000122	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1429244000123	putative active site [active]
1429244000124	catalytic residue [active]
1429244000125	Protein of unknown function (DUF2757); Region: DUF2757; pfam10955
1429244000126	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1429244000127	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1429244000128	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244000129	ATP binding site [chemical binding]; other site
1429244000130	putative Mg++ binding site [ion binding]; other site
1429244000131	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244000132	nucleotide binding region [chemical binding]; other site
1429244000133	ATP-binding site [chemical binding]; other site
1429244000134	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1429244000135	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1429244000136	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
1429244000137	stage V sporulation protein T; Region: spore_V_T; TIGR02851
1429244000138	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1429244000139	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1429244000140	Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only]; Region: COG3956
1429244000141	N-terminal S-AdoMet dependent methylase domain of Bacillus subtilis YabN and related proteins; Region: YabN_N; cd11723
1429244000142	putative SAM binding site [chemical binding]; other site
1429244000143	putative homodimer interface [polypeptide binding]; other site
1429244000144	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1429244000145	homodimer interface [polypeptide binding]; other site
1429244000146	metal binding site [ion binding]; metal-binding site
1429244000147	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1429244000148	homodimer interface [polypeptide binding]; other site
1429244000149	active site
1429244000150	putative chemical substrate binding site [chemical binding]; other site
1429244000151	metal binding site [ion binding]; metal-binding site
1429244000152	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1429244000153	IHF dimer interface [polypeptide binding]; other site
1429244000154	IHF - DNA interface [nucleotide binding]; other site
1429244000155	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244000156	RNA binding surface [nucleotide binding]; other site
1429244000157	YabP family; Region: YabP; cl06766
1429244000158	Spore cortex protein YabQ (Spore_YabQ); Region: Spore_YabQ; cl09801
1429244000159	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1429244000160	Septum formation initiator; Region: DivIC; cl17659
1429244000161	hypothetical protein; Provisional; Region: PRK08582
1429244000162	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1429244000163	RNA binding site [nucleotide binding]; other site
1429244000164	stage II sporulation protein E; Region: spore_II_E; TIGR02865
1429244000165	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1429244000166	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1429244000167	metal ion-dependent adhesion site (MIDAS); other site
1429244000168	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
1429244000169	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1429244000170	active site
1429244000171	ATP binding site [chemical binding]; other site
1429244000172	substrate binding site [chemical binding]; other site
1429244000173	activation loop (A-loop); other site
1429244000174	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1429244000175	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1429244000176	Ligand Binding Site [chemical binding]; other site
1429244000177	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1429244000178	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244000179	active site
1429244000180	FtsH Extracellular; Region: FtsH_ext; pfam06480
1429244000181	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1429244000182	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244000183	Walker A motif; other site
1429244000184	ATP binding site [chemical binding]; other site
1429244000185	Walker B motif; other site
1429244000186	arginine finger; other site
1429244000187	Peptidase family M41; Region: Peptidase_M41; pfam01434
1429244000188	L-aspartate oxidase; Provisional; Region: PRK06175
1429244000189	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
1429244000190	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1429244000191	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
1429244000192	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1429244000193	dimerization interface [polypeptide binding]; other site
1429244000194	active site
1429244000195	pantothenate kinase; Reviewed; Region: PRK13318
1429244000196	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1429244000197	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1429244000198	dimerization interface [polypeptide binding]; other site
1429244000199	domain crossover interface; other site
1429244000200	redox-dependent activation switch; other site
1429244000201	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1429244000202	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1429244000203	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1429244000204	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1429244000205	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1429244000206	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1429244000207	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1429244000208	glutamine binding [chemical binding]; other site
1429244000209	catalytic triad [active]
1429244000210	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1429244000211	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
1429244000212	homodimer interface [polypeptide binding]; other site
1429244000213	substrate-cofactor binding pocket; other site
1429244000214	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244000215	catalytic residue [active]
1429244000216	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1429244000217	dihydropteroate synthase; Region: DHPS; TIGR01496
1429244000218	substrate binding pocket [chemical binding]; other site
1429244000219	dimer interface [polypeptide binding]; other site
1429244000220	inhibitor binding site; inhibition site
1429244000221	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1429244000222	homooctamer interface [polypeptide binding]; other site
1429244000223	active site
1429244000224	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1429244000225	catalytic center binding site [active]
1429244000226	ATP binding site [chemical binding]; other site
1429244000227	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1429244000228	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1429244000229	FMN binding site [chemical binding]; other site
1429244000230	active site
1429244000231	catalytic residues [active]
1429244000232	substrate binding site [chemical binding]; other site
1429244000233	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1429244000234	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1429244000235	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1429244000236	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1429244000237	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1429244000238	dimer interface [polypeptide binding]; other site
1429244000239	putative anticodon binding site; other site
1429244000240	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1429244000241	motif 1; other site
1429244000242	active site
1429244000243	motif 2; other site
1429244000244	motif 3; other site
1429244000245	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1429244000246	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1429244000247	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
1429244000248	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1429244000249	NAD binding site [chemical binding]; other site
1429244000250	homotetramer interface [polypeptide binding]; other site
1429244000251	homodimer interface [polypeptide binding]; other site
1429244000252	substrate binding site [chemical binding]; other site
1429244000253	active site
1429244000254	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1429244000255	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1429244000256	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1429244000257	Walker A/P-loop; other site
1429244000258	ATP binding site [chemical binding]; other site
1429244000259	Q-loop/lid; other site
1429244000260	ABC transporter signature motif; other site
1429244000261	Walker B; other site
1429244000262	D-loop; other site
1429244000263	H-loop/switch region; other site
1429244000264	TOBE domain; Region: TOBE; pfam03459
1429244000265	HPr kinase/phosphorylase; Provisional; Region: PRK05428
1429244000266	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1429244000267	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1429244000268	Hpr binding site; other site
1429244000269	active site
1429244000270	homohexamer subunit interaction site [polypeptide binding]; other site
1429244000271	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
1429244000272	pyrophosphatase PpaX; Provisional; Region: PRK13288
1429244000273	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244000274	active site
1429244000275	motif I; other site
1429244000276	motif II; other site
1429244000277	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1429244000278	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1429244000279	trimer interface [polypeptide binding]; other site
1429244000280	active site
1429244000281	substrate binding site [chemical binding]; other site
1429244000282	CoA binding site [chemical binding]; other site
1429244000283	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1429244000284	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1429244000285	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1429244000286	ATP phosphoribosyltransferase, regulatory subunit; Region: hisZ_biosyn_reg; TIGR00443
1429244000287	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1429244000288	dimer interface [polypeptide binding]; other site
1429244000289	motif 1; other site
1429244000290	active site
1429244000291	motif 2; other site
1429244000292	motif 3; other site
1429244000293	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
1429244000294	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
1429244000295	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1429244000296	histidinol dehydrogenase; Region: hisD; TIGR00069
1429244000297	NAD binding site [chemical binding]; other site
1429244000298	dimerization interface [polypeptide binding]; other site
1429244000299	product binding site; other site
1429244000300	substrate binding site [chemical binding]; other site
1429244000301	zinc binding site [ion binding]; other site
1429244000302	catalytic residues [active]
1429244000303	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1429244000304	putative active site pocket [active]
1429244000305	4-fold oligomerization interface [polypeptide binding]; other site
1429244000306	metal binding residues [ion binding]; metal-binding site
1429244000307	3-fold/trimer interface [polypeptide binding]; other site
1429244000308	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
1429244000309	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1429244000310	putative active site [active]
1429244000311	oxyanion strand; other site
1429244000312	catalytic triad [active]
1429244000313	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1429244000314	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1429244000315	catalytic residues [active]
1429244000316	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1429244000317	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1429244000318	substrate binding site [chemical binding]; other site
1429244000319	glutamase interaction surface [polypeptide binding]; other site
1429244000320	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1429244000321	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
1429244000322	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1429244000323	metal binding site [ion binding]; metal-binding site
1429244000324	histidinol-phosphatase; Provisional; Region: PRK07328
1429244000325	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
1429244000326	active site
1429244000327	dimer interface [polypeptide binding]; other site
1429244000328	TPR repeat; Region: TPR_11; pfam13414
1429244000329	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244000330	TPR motif; other site
1429244000331	binding surface
1429244000332	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244000333	TPR motif; other site
1429244000334	binding surface
1429244000335	HEAT repeats; Region: HEAT_2; pfam13646
1429244000336	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1429244000337	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1429244000338	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244000339	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1429244000340	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244000341	nucleotide binding site [chemical binding]; other site
1429244000342	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1429244000343	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1429244000344	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1429244000345	phosphate binding site [ion binding]; other site
1429244000346	putative substrate binding pocket [chemical binding]; other site
1429244000347	dimer interface [polypeptide binding]; other site
1429244000348	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
1429244000349	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
1429244000350	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1429244000351	dimerization domain swap beta strand [polypeptide binding]; other site
1429244000352	regulatory protein interface [polypeptide binding]; other site
1429244000353	active site
1429244000354	regulatory phosphorylation site [posttranslational modification]; other site
1429244000355	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
1429244000356	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244000357	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1429244000358	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1429244000359	Clp protease; Region: CLP_protease; pfam00574
1429244000360	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1429244000361	oligomer interface [polypeptide binding]; other site
1429244000362	active site residues [active]
1429244000363	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1429244000364	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1429244000365	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1429244000366	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1429244000367	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1429244000368	Phosphoglycerate kinase; Region: PGK; pfam00162
1429244000369	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1429244000370	substrate binding site [chemical binding]; other site
1429244000371	hinge regions; other site
1429244000372	ADP binding site [chemical binding]; other site
1429244000373	catalytic site [active]
1429244000374	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1429244000375	triosephosphate isomerase; Provisional; Region: PRK14565
1429244000376	substrate binding site [chemical binding]; other site
1429244000377	dimer interface [polypeptide binding]; other site
1429244000378	catalytic triad [active]
1429244000379	phosphoglyceromutase; Provisional; Region: PRK05434
1429244000380	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1429244000381	enolase; Provisional; Region: eno; PRK00077
1429244000382	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1429244000383	dimer interface [polypeptide binding]; other site
1429244000384	metal binding site [ion binding]; metal-binding site
1429244000385	substrate binding pocket [chemical binding]; other site
1429244000386	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1429244000387	ribonuclease R; Region: RNase_R; TIGR02063
1429244000388	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1429244000389	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1429244000390	RNB domain; Region: RNB; pfam00773
1429244000391	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1429244000392	RNA binding site [nucleotide binding]; other site
1429244000393	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1429244000394	SmpB-tmRNA interface; other site
1429244000395	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1429244000396	Predicted membrane protein [Function unknown]; Region: COG2259
1429244000397	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1429244000398	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244000399	Zn binding site [ion binding]; other site
1429244000400	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1429244000401	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244000402	Zn binding site [ion binding]; other site
1429244000403	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244000404	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244000405	dimerization interface [polypeptide binding]; other site
1429244000406	putative DNA binding site [nucleotide binding]; other site
1429244000407	putative Zn2+ binding site [ion binding]; other site
1429244000408	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1429244000409	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244000410	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1429244000411	Predicted transcriptional regulators [Transcription]; Region: COG1695
1429244000412	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1429244000413	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1429244000414	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1429244000415	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244000416	active site
1429244000417	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244000418	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244000419	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1429244000420	DNA-binding site [nucleotide binding]; DNA binding site
1429244000421	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1429244000422	putative phosphoketolase; Provisional; Region: PRK05261
1429244000423	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
1429244000424	TPP-binding site; other site
1429244000425	XFP C-terminal domain; Region: XFP_C; pfam09363
1429244000426	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244000427	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244000428	active site
1429244000429	catalytic tetrad [active]
1429244000430	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1429244000431	TFIIB zinc-binding; Region: TF_Zn_Ribbon; pfam08271
1429244000432	Repair protein; Region: Repair_PSII; pfam04536
1429244000433	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
1429244000434	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
1429244000435	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1429244000436	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1429244000437	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1429244000438	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1429244000439	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; cl01412
1429244000440	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244000441	non-specific DNA binding site [nucleotide binding]; other site
1429244000442	salt bridge; other site
1429244000443	sequence-specific DNA binding site [nucleotide binding]; other site
1429244000444	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244000445	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000446	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1429244000447	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1429244000448	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1429244000449	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1429244000450	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1429244000451	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1429244000452	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1429244000453	classical (c) SDRs; Region: SDR_c; cd05233
1429244000454	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1429244000455	NAD(P) binding site [chemical binding]; other site
1429244000456	active site
1429244000457	MFS/sugar transport protein; Region: MFS_2; pfam13347
1429244000458	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244000459	putative substrate translocation pore; other site
1429244000460	Glycosyl hydrolase family 52; Region: Glyco_hydro_52; pfam03512
1429244000461	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244000462	Phytase; Region: Phytase; cl17685
1429244000463	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244000464	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000465	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1429244000466	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1429244000467	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1429244000468	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1429244000469	MATE family multidrug exporter; Provisional; Region: PRK10189
1429244000470	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1429244000471	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1429244000472	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1429244000473	NAD(P) binding site [chemical binding]; other site
1429244000474	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244000475	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244000476	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1429244000477	putative dimerization interface [polypeptide binding]; other site
1429244000478	RDD family; Region: RDD; pfam06271
1429244000479	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1429244000480	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1429244000481	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244000482	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000483	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244000484	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000485	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244000486	active site
1429244000487	phosphorylation site [posttranslational modification]
1429244000488	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1429244000489	active site
1429244000490	P-loop; other site
1429244000491	phosphorylation site [posttranslational modification]
1429244000492	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1429244000493	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1429244000494	alpha-mannosidase; Provisional; Region: PRK09819
1429244000495	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1429244000496	active site
1429244000497	metal binding site [ion binding]; metal-binding site
1429244000498	catalytic site [active]
1429244000499	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1429244000500	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1429244000501	HTH domain; Region: HTH_11; pfam08279
1429244000502	Mga helix-turn-helix domain; Region: Mga; pfam05043
1429244000503	PRD domain; Region: PRD; pfam00874
1429244000504	PRD domain; Region: PRD; pfam00874
1429244000505	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1429244000506	active site
1429244000507	P-loop; other site
1429244000508	phosphorylation site [posttranslational modification]
1429244000509	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244000510	active site
1429244000511	phosphorylation site [posttranslational modification]
1429244000512	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1429244000513	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1429244000514	Domain of unknown function (DUF1963); Region: DUF1963; cl01600
1429244000515	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244000516	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1429244000517	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1429244000518	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1429244000519	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1429244000520	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1429244000521	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244000522	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000523	dimer interface [polypeptide binding]; other site
1429244000524	conserved gate region; other site
1429244000525	putative PBP binding loops; other site
1429244000526	ABC-ATPase subunit interface; other site
1429244000527	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000528	dimer interface [polypeptide binding]; other site
1429244000529	conserved gate region; other site
1429244000530	putative PBP binding loops; other site
1429244000531	ABC-ATPase subunit interface; other site
1429244000532	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244000533	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1429244000534	dimerization interface [polypeptide binding]; other site
1429244000535	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244000536	Histidine kinase; Region: His_kinase; pfam06580
1429244000537	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1429244000538	ATP binding site [chemical binding]; other site
1429244000539	Mg2+ binding site [ion binding]; other site
1429244000540	G-X-G motif; other site
1429244000541	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
1429244000542	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244000543	active site
1429244000544	phosphorylation site [posttranslational modification]
1429244000545	intermolecular recognition site; other site
1429244000546	dimerization interface [polypeptide binding]; other site
1429244000547	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000548	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1429244000549	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1429244000550	ATP-binding site [chemical binding]; other site
1429244000551	Sugar specificity; other site
1429244000552	Pyrimidine base specificity; other site
1429244000553	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
1429244000554	Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated...; Region: PTX; cl00102
1429244000555	Pectate lyase; Region: Pec_lyase_C; cl01593
1429244000556	maltodextrin phosphorylase; Provisional; Region: PRK14985
1429244000557	SNF2 Helicase protein; Region: DUF3670; pfam12419
1429244000558	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1429244000559	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244000560	ATP binding site [chemical binding]; other site
1429244000561	putative Mg++ binding site [ion binding]; other site
1429244000562	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244000563	nucleotide binding region [chemical binding]; other site
1429244000564	ATP-binding site [chemical binding]; other site
1429244000565	SWIM zinc finger; Region: SWIM; pfam04434
1429244000566	Predicted esterase [General function prediction only]; Region: COG0400
1429244000567	putative hydrolase; Provisional; Region: PRK11460
1429244000568	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1429244000569	dimer interface [polypeptide binding]; other site
1429244000570	FMN binding site [chemical binding]; other site
1429244000571	SnoaL-like domain; Region: SnoaL_2; pfam12680
1429244000572	Sugar fermentation stimulation protein; Region: SfsA; cl00647
1429244000573	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1429244000574	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244000575	motif II; other site
1429244000576	maltose phosphorylase; Provisional; Region: PRK13807
1429244000577	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1429244000578	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1429244000579	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1429244000580	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244000581	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244000582	DNA binding site [nucleotide binding]
1429244000583	domain linker motif; other site
1429244000584	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1429244000585	putative dimerization interface [polypeptide binding]; other site
1429244000586	putative ligand binding site [chemical binding]; other site
1429244000587	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
1429244000588	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244000589	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244000590	active site turn [active]
1429244000591	phosphorylation site [posttranslational modification]
1429244000592	Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins; Region: RgfB-like; cd09079
1429244000593	putative catalytic site [active]
1429244000594	putative metal binding site [ion binding]; other site
1429244000595	putative phosphate binding site [ion binding]; other site
1429244000596	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244000597	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244000598	putative substrate translocation pore; other site
1429244000599	DinB family; Region: DinB; cl17821
1429244000600	DinB superfamily; Region: DinB_2; pfam12867
1429244000601	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244000602	MarR family; Region: MarR; pfam01047
1429244000603	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244000604	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244000605	active site
1429244000606	phosphorylation site [posttranslational modification]
1429244000607	intermolecular recognition site; other site
1429244000608	dimerization interface [polypeptide binding]; other site
1429244000609	YcbB domain; Region: YcbB; pfam08664
1429244000610	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244000611	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244000612	ATP binding site [chemical binding]; other site
1429244000613	Mg2+ binding site [ion binding]; other site
1429244000614	G-X-G motif; other site
1429244000615	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1429244000616	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1429244000617	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244000618	PAS fold; Region: PAS_3; pfam08447
1429244000619	putative active site [active]
1429244000620	heme pocket [chemical binding]; other site
1429244000621	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244000622	PAS fold; Region: PAS_3; pfam08447
1429244000623	putative active site [active]
1429244000624	heme pocket [chemical binding]; other site
1429244000625	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244000626	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244000627	dimer interface [polypeptide binding]; other site
1429244000628	putative CheW interface [polypeptide binding]; other site
1429244000629	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
1429244000630	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244000631	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1429244000632	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244000633	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000634	dimer interface [polypeptide binding]; other site
1429244000635	conserved gate region; other site
1429244000636	putative PBP binding loops; other site
1429244000637	ABC-ATPase subunit interface; other site
1429244000638	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244000639	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244000640	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000641	dimer interface [polypeptide binding]; other site
1429244000642	conserved gate region; other site
1429244000643	putative PBP binding loops; other site
1429244000644	ABC-ATPase subunit interface; other site
1429244000645	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244000646	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244000647	Walker A/P-loop; other site
1429244000648	ATP binding site [chemical binding]; other site
1429244000649	Q-loop/lid; other site
1429244000650	ABC transporter signature motif; other site
1429244000651	Walker B; other site
1429244000652	D-loop; other site
1429244000653	H-loop/switch region; other site
1429244000654	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244000655	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244000656	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244000657	Walker A/P-loop; other site
1429244000658	ATP binding site [chemical binding]; other site
1429244000659	Q-loop/lid; other site
1429244000660	ABC transporter signature motif; other site
1429244000661	Walker B; other site
1429244000662	D-loop; other site
1429244000663	H-loop/switch region; other site
1429244000664	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1429244000665	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1429244000666	sporulation sigma factor SigF; Validated; Region: PRK05572
1429244000667	Y-family of DNA polymerases; Region: PolY; cl12025
1429244000668	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1429244000669	DNA binding residues [nucleotide binding]
1429244000670	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244000671	Coenzyme A binding pocket [chemical binding]; other site
1429244000672	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1429244000673	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1429244000674	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1429244000675	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1429244000676	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244000677	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244000678	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1429244000679	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244000680	active site
1429244000681	phosphorylation site [posttranslational modification]
1429244000682	intermolecular recognition site; other site
1429244000683	dimerization interface [polypeptide binding]; other site
1429244000684	LytTr DNA-binding domain; Region: LytTR; smart00850
1429244000685	Cupin domain; Region: Cupin_2; pfam07883
1429244000686	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244000687	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000688	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000689	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244000690	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244000691	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244000692	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
1429244000693	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1429244000694	active site
1429244000695	zinc binding site [ion binding]; other site
1429244000696	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1429244000697	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1429244000698	NAD binding site [chemical binding]; other site
1429244000699	substrate binding site [chemical binding]; other site
1429244000700	catalytic Zn binding site [ion binding]; other site
1429244000701	tetramer interface [polypeptide binding]; other site
1429244000702	structural Zn binding site [ion binding]; other site
1429244000703	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244000704	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244000705	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244000706	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244000707	putative substrate translocation pore; other site
1429244000708	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244000709	active site
1429244000710	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244000711	catalytic tetrad [active]
1429244000712	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244000713	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244000714	DNA binding site [nucleotide binding]
1429244000715	domain linker motif; other site
1429244000716	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1429244000717	dimerization interface [polypeptide binding]; other site
1429244000718	ligand binding site [chemical binding]; other site
1429244000719	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1429244000720	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244000721	substrate binding [chemical binding]; other site
1429244000722	active site
1429244000723	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244000724	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1429244000725	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244000726	active site turn [active]
1429244000727	phosphorylation site [posttranslational modification]
1429244000728	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244000729	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244000730	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000731	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
1429244000732	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1429244000733	domain interfaces; other site
1429244000734	active site
1429244000735	Spore germination protein; Region: Spore_permease; cl17796
1429244000736	Spore germination protein; Region: Spore_permease; cl17796
1429244000737	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244000738	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244000739	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244000740	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1429244000741	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1429244000742	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
1429244000743	substrate binding site [chemical binding]; other site
1429244000744	active site
1429244000745	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1429244000746	cspA; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244000747	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1429244000748	DNA-binding site [nucleotide binding]; DNA binding site
1429244000749	RNA-binding motif; other site
1429244000750	Cold-inducible protein YdjO; Region: YdjO; pfam14169
1429244000751	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244000752	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1429244000753	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1429244000754	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244000755	Coenzyme A binding pocket [chemical binding]; other site
1429244000756	Predicted transcriptional regulators [Transcription]; Region: COG1725
1429244000757	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244000758	DNA-binding site [nucleotide binding]; DNA binding site
1429244000759	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1429244000760	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1429244000761	Walker A/P-loop; other site
1429244000762	ATP binding site [chemical binding]; other site
1429244000763	Q-loop/lid; other site
1429244000764	ABC transporter signature motif; other site
1429244000765	Walker B; other site
1429244000766	D-loop; other site
1429244000767	H-loop/switch region; other site
1429244000768	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1429244000769	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244000770	Protein of unknown function (DUF1453); Region: DUF1453; cl02009
1429244000771	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244000772	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244000773	DNA binding site [nucleotide binding]
1429244000774	domain linker motif; other site
1429244000775	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244000776	dimerization interface [polypeptide binding]; other site
1429244000777	ligand binding site [chemical binding]; other site
1429244000778	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1429244000779	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1429244000780	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1429244000781	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1429244000782	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244000783	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244000784	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000785	dimer interface [polypeptide binding]; other site
1429244000786	conserved gate region; other site
1429244000787	putative PBP binding loops; other site
1429244000788	ABC-ATPase subunit interface; other site
1429244000789	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244000790	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000791	dimer interface [polypeptide binding]; other site
1429244000792	conserved gate region; other site
1429244000793	putative PBP binding loops; other site
1429244000794	ABC-ATPase subunit interface; other site
1429244000795	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1429244000796	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244000797	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244000798	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244000799	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244000800	Walker A/P-loop; other site
1429244000801	ATP binding site [chemical binding]; other site
1429244000802	Q-loop/lid; other site
1429244000803	ABC transporter signature motif; other site
1429244000804	Walker B; other site
1429244000805	D-loop; other site
1429244000806	H-loop/switch region; other site
1429244000807	Cys-rich peptide radical SAM maturase CcpM; Region: rSAM_ocin_clost; TIGR04068
1429244000808	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244000809	FeS/SAM binding site; other site
1429244000810	peptide maturation system protein, TIGR04066 family; Region: nat_prod_clost
1429244000811	peptide maturation system acyl carrier-related protein; Region: ocin_ACP_rel; TIGR04069
1429244000812	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1429244000813	Peptidase S8 family domain, uncharacterized subfamily 8; Region: Peptidases_S8_8; cd07492
1429244000814	active site
1429244000815	catalytic triad [active]
1429244000816	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1429244000817	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1429244000818	HSP90 family protein; Provisional; Region: PRK14083
1429244000819	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244000820	ATP binding site [chemical binding]; other site
1429244000821	G-X-G motif; other site
1429244000822	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1429244000823	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
1429244000824	active site
1429244000825	catalytic site [active]
1429244000826	metal binding site [ion binding]; metal-binding site
1429244000827	dimer interface [polypeptide binding]; other site
1429244000828	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244000829	S-adenosylmethionine binding site [chemical binding]; other site
1429244000830	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1429244000831	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1429244000832	active site
1429244000833	tetramer interface; other site
1429244000834	Predicted membrane protein [Function unknown]; Region: COG2246
1429244000835	GtrA-like protein; Region: GtrA; pfam04138
1429244000836	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1429244000837	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1429244000838	Ligand binding site; other site
1429244000839	Putative Catalytic site; other site
1429244000840	DXD motif; other site
1429244000841	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1429244000842	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1429244000843	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244000844	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244000845	active site
1429244000846	phosphorylation site [posttranslational modification]
1429244000847	intermolecular recognition site; other site
1429244000848	dimerization interface [polypeptide binding]; other site
1429244000849	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244000850	DNA binding site [nucleotide binding]
1429244000851	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244000852	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244000853	dimerization interface [polypeptide binding]; other site
1429244000854	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244000855	dimer interface [polypeptide binding]; other site
1429244000856	phosphorylation site [posttranslational modification]
1429244000857	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244000858	ATP binding site [chemical binding]; other site
1429244000859	Mg2+ binding site [ion binding]; other site
1429244000860	G-X-G motif; other site
1429244000861	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1429244000862	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
1429244000863	Peptidase S8 family domain in Vpr-like proteins; Region: Peptidases_S8_subtilisin_Vpr-like; cd07474
1429244000864	putative active site [active]
1429244000865	catalytic triad [active]
1429244000866	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
1429244000867	PA/protease or protease-like domain interface [polypeptide binding]; other site
1429244000868	Peptidase S8 family domain in Vpr-like proteins; Region: Peptidases_S8_subtilisin_Vpr-like; cd07474
1429244000869	S-layer homology domain; Region: SLH; pfam00395
1429244000870	S-layer homology domain; Region: SLH; pfam00395
1429244000871	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
1429244000872	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1429244000873	DHHA2 domain; Region: DHHA2; pfam02833
1429244000874	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1429244000875	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1429244000876	substrate binding pocket [chemical binding]; other site
1429244000877	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244000878	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244000879	MarR family; Region: MarR; pfam01047
1429244000880	Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906
1429244000881	DNA polymerase LigD, ligase domain; Region: NHEJ_ligase_lig; TIGR02779
1429244000882	active site
1429244000883	DNA binding site [nucleotide binding]
1429244000884	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971
1429244000885	DNA binding site [nucleotide binding]
1429244000886	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244000887	Coenzyme A binding pocket [chemical binding]; other site
1429244000888	Predicted membrane protein [Function unknown]; Region: COG2322
1429244000889	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244000890	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244000891	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244000892	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000893	dimer interface [polypeptide binding]; other site
1429244000894	conserved gate region; other site
1429244000895	putative PBP binding loops; other site
1429244000896	ABC-ATPase subunit interface; other site
1429244000897	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244000898	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000899	dimer interface [polypeptide binding]; other site
1429244000900	conserved gate region; other site
1429244000901	putative PBP binding loops; other site
1429244000902	ABC-ATPase subunit interface; other site
1429244000903	beta-N-acetylglucosaminidase; Region: NAGidase; pfam07555
1429244000904	Protein of unknown function (DUF4127); Region: DUF4127; pfam13552
1429244000905	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1429244000906	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1429244000907	putative active site cavity [active]
1429244000908	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1429244000909	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1429244000910	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1429244000911	putative active site [active]
1429244000912	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1429244000913	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244000914	nucleotide binding site [chemical binding]; other site
1429244000915	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
1429244000916	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244000917	PAS domain; Region: PAS_9; pfam13426
1429244000918	putative active site [active]
1429244000919	heme pocket [chemical binding]; other site
1429244000920	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1429244000921	Histidine kinase; Region: HisKA_3; pfam07730
1429244000922	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244000923	ATP binding site [chemical binding]; other site
1429244000924	Mg2+ binding site [ion binding]; other site
1429244000925	G-X-G motif; other site
1429244000926	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244000927	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244000928	active site
1429244000929	phosphorylation site [posttranslational modification]
1429244000930	intermolecular recognition site; other site
1429244000931	dimerization interface [polypeptide binding]; other site
1429244000932	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244000933	DNA binding residues [nucleotide binding]
1429244000934	dimerization interface [polypeptide binding]; other site
1429244000935	GAF domain; Region: GAF; cl17456
1429244000936	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1429244000937	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1429244000938	ligand binding site [chemical binding]; other site
1429244000939	flexible hinge region; other site
1429244000940	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1429244000941	putative switch regulator; other site
1429244000942	non-specific DNA interactions [nucleotide binding]; other site
1429244000943	DNA binding site [nucleotide binding]
1429244000944	sequence specific DNA binding site [nucleotide binding]; other site
1429244000945	putative cAMP binding site [chemical binding]; other site
1429244000946	5S ribosomal RNA rRNA prediction is too short
1429244000947	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244000948	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244000949	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1429244000950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000951	dimer interface [polypeptide binding]; other site
1429244000952	conserved gate region; other site
1429244000953	putative PBP binding loops; other site
1429244000954	ABC-ATPase subunit interface; other site
1429244000955	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244000956	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244000957	dimer interface [polypeptide binding]; other site
1429244000958	conserved gate region; other site
1429244000959	putative PBP binding loops; other site
1429244000960	ABC-ATPase subunit interface; other site
1429244000961	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244000962	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244000963	dimerization interface [polypeptide binding]; other site
1429244000964	Histidine kinase; Region: His_kinase; pfam06580
1429244000965	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244000966	ATP binding site [chemical binding]; other site
1429244000967	Mg2+ binding site [ion binding]; other site
1429244000968	G-X-G motif; other site
1429244000969	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244000970	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244000971	active site
1429244000972	phosphorylation site [posttranslational modification]
1429244000973	intermolecular recognition site; other site
1429244000974	dimerization interface [polypeptide binding]; other site
1429244000975	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244000976	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000977	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244000978	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244000979	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244000980	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244000981	dimerization interface [polypeptide binding]; other site
1429244000982	aromatic acid decarboxylase; Validated; Region: PRK05920
1429244000983	Flavoprotein; Region: Flavoprotein; pfam02441
1429244000984	UbiD family decarboxylase; Region: TIGR00148
1429244000985	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244000986	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244000987	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
1429244000988	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
1429244000989	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
1429244000990	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
1429244000991	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1429244000992	ACT_3PGDH-like CD includes the C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-like; cd04879
1429244000993	L-serine binding site [chemical binding]; other site
1429244000994	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244000995	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244000996	Walker A/P-loop; other site
1429244000997	ATP binding site [chemical binding]; other site
1429244000998	Q-loop/lid; other site
1429244000999	ABC transporter signature motif; other site
1429244001000	Walker B; other site
1429244001001	D-loop; other site
1429244001002	H-loop/switch region; other site
1429244001003	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1429244001004	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1429244001005	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244001006	Walker A/P-loop; other site
1429244001007	ATP binding site [chemical binding]; other site
1429244001008	Q-loop/lid; other site
1429244001009	ABC transporter signature motif; other site
1429244001010	Walker B; other site
1429244001011	D-loop; other site
1429244001012	H-loop/switch region; other site
1429244001013	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1429244001014	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244001015	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001016	dimer interface [polypeptide binding]; other site
1429244001017	conserved gate region; other site
1429244001018	putative PBP binding loops; other site
1429244001019	ABC-ATPase subunit interface; other site
1429244001020	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244001021	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001022	dimer interface [polypeptide binding]; other site
1429244001023	conserved gate region; other site
1429244001024	putative PBP binding loops; other site
1429244001025	ABC-ATPase subunit interface; other site
1429244001026	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244001027	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
1429244001028	peptide binding site [polypeptide binding]; other site
1429244001029	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244001030	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244001031	dimerization interface [polypeptide binding]; other site
1429244001032	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001033	dimer interface [polypeptide binding]; other site
1429244001034	conserved gate region; other site
1429244001035	putative PBP binding loops; other site
1429244001036	ABC-ATPase subunit interface; other site
1429244001037	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1429244001038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001039	dimer interface [polypeptide binding]; other site
1429244001040	conserved gate region; other site
1429244001041	putative PBP binding loops; other site
1429244001042	ABC-ATPase subunit interface; other site
1429244001043	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244001044	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244001045	substrate binding pocket [chemical binding]; other site
1429244001046	membrane-bound complex binding site; other site
1429244001047	hinge residues; other site
1429244001048	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244001049	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244001050	Walker A/P-loop; other site
1429244001051	ATP binding site [chemical binding]; other site
1429244001052	Q-loop/lid; other site
1429244001053	ABC transporter signature motif; other site
1429244001054	Walker B; other site
1429244001055	D-loop; other site
1429244001056	H-loop/switch region; other site
1429244001057	Cupin superfamily (DUF985); Region: Cupin_5; cl01418
1429244001058	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
1429244001059	active site
1429244001060	catalytic site [active]
1429244001061	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1429244001062	Collagen binding domain; Region: Collagen_bind; pfam05737
1429244001063	Collagen binding domain; Region: Collagen_bind; pfam05737
1429244001064	Collagen binding domain; Region: Collagen_bind; pfam05737
1429244001065	Collagen binding domain; Region: Collagen_bind; pfam05737
1429244001066	Cna protein B-type domain; Region: Cna_B; pfam05738
1429244001067	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244001068	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244001069	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001070	Protein of unknown function (DUF445); Region: DUF445; pfam04286
1429244001071	conserved hypothetical protein; Region: TIGR02328
1429244001072	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; pfam03013
1429244001073	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1429244001074	dimer interface [polypeptide binding]; other site
1429244001075	FMN binding site [chemical binding]; other site
1429244001076	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244001077	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244001078	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244001079	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1429244001080	active site
1429244001081	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1429244001082	Reeler-like domain of YcnI and similar proteins; Region: YcnI_like; cd08545
1429244001083	CopC domain; Region: CopC; pfam04234
1429244001084	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1429244001085	YtkA-like; Region: YtkA; pfam13115
1429244001086	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244001087	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244001088	metal binding site [ion binding]; metal-binding site
1429244001089	active site
1429244001090	I-site; other site
1429244001091	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1429244001092	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244001093	Zn2+ binding site [ion binding]; other site
1429244001094	Mg2+ binding site [ion binding]; other site
1429244001095	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1429244001096	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001097	putative substrate translocation pore; other site
1429244001098	Staphylococcus aureus copper-sensitive operon repressor (CsoR), and related domains; this family was previously known as part of DUF156; Region: SaCsoR-like_DUF156; cd10152
1429244001099	putative homodimer interface [polypeptide binding]; other site
1429244001100	putative homotetramer interface [polypeptide binding]; other site
1429244001101	allosteric switch controlling residues; other site
1429244001102	putative metal binding site [ion binding]; other site
1429244001103	putative homodimer-homodimer interface [polypeptide binding]; other site
1429244001104	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1429244001105	metal-binding site [ion binding]
1429244001106	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1429244001107	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1429244001108	metal-binding site [ion binding]
1429244001109	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1429244001110	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1429244001111	metal-binding site [ion binding]
1429244001112	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1429244001113	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1429244001114	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1429244001115	dimer interface [polypeptide binding]; other site
1429244001116	FMN binding site [chemical binding]; other site
1429244001117	NADPH bind site [chemical binding]; other site
1429244001118	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1429244001119	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1429244001120	active site
1429244001121	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1429244001122	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1429244001123	Walker A/P-loop; other site
1429244001124	ATP binding site [chemical binding]; other site
1429244001125	Q-loop/lid; other site
1429244001126	ABC transporter signature motif; other site
1429244001127	Walker B; other site
1429244001128	D-loop; other site
1429244001129	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1429244001130	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001131	dimer interface [polypeptide binding]; other site
1429244001132	conserved gate region; other site
1429244001133	putative PBP binding loops; other site
1429244001134	ABC-ATPase subunit interface; other site
1429244001135	Domain of unknown function DUF77; Region: DUF77; pfam01910
1429244001136	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1429244001137	NMT1/THI5 like; Region: NMT1; pfam09084
1429244001138	Uncharacterized stress protein (general stress protein 26) [General function prediction only]; Region: COG3871
1429244001139	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1429244001140	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1429244001141	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1429244001142	active site
1429244001143	metal binding site [ion binding]; metal-binding site
1429244001144	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1429244001145	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1429244001146	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276
1429244001147	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1429244001148	putative NAD(P) binding site [chemical binding]; other site
1429244001149	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
1429244001150	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1429244001151	substrate binding site [chemical binding]; other site
1429244001152	activation loop (A-loop); other site
1429244001153	Strictosidine synthase; Region: Str_synth; pfam03088
1429244001154	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1429244001155	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244001156	NAD(P) binding site [chemical binding]; other site
1429244001157	active site
1429244001158	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1429244001159	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1429244001160	Ca binding site [ion binding]; other site
1429244001161	active site
1429244001162	catalytic site [active]
1429244001163	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1429244001164	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1429244001165	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244001166	active site
1429244001167	motif I; other site
1429244001168	motif II; other site
1429244001169	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1429244001170	Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs; Region: CE4_BsPdaA_like; cd10948
1429244001171	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
1429244001172	NodB motif; other site
1429244001173	active site
1429244001174	catalytic site [active]
1429244001175	Cd binding site [ion binding]; other site
1429244001176	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1429244001177	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1429244001178	Walker A/P-loop; other site
1429244001179	ATP binding site [chemical binding]; other site
1429244001180	Q-loop/lid; other site
1429244001181	ABC transporter signature motif; other site
1429244001182	Walker B; other site
1429244001183	D-loop; other site
1429244001184	H-loop/switch region; other site
1429244001185	NIL domain; Region: NIL; pfam09383
1429244001186	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001187	ABC-ATPase subunit interface; other site
1429244001188	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244001189	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1429244001190	DNA binding residues [nucleotide binding]
1429244001191	putative dimer interface [polypeptide binding]; other site
1429244001192	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244001193	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244001194	active site
1429244001195	catalytic tetrad [active]
1429244001196	S-layer homology domain; Region: SLH; pfam00395
1429244001197	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
1429244001198	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244001199	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244001200	dimer interface [polypeptide binding]; other site
1429244001201	phosphorylation site [posttranslational modification]
1429244001202	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001203	ATP binding site [chemical binding]; other site
1429244001204	Mg2+ binding site [ion binding]; other site
1429244001205	G-X-G motif; other site
1429244001206	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1429244001207	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001208	active site
1429244001209	phosphorylation site [posttranslational modification]
1429244001210	intermolecular recognition site; other site
1429244001211	dimerization interface [polypeptide binding]; other site
1429244001212	Histidine kinase; Region: His_kinase; pfam06580
1429244001213	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001214	ATP binding site [chemical binding]; other site
1429244001215	Mg2+ binding site [ion binding]; other site
1429244001216	G-X-G motif; other site
1429244001217	Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms]; Region: COG3947
1429244001218	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001219	active site
1429244001220	phosphorylation site [posttranslational modification]
1429244001221	intermolecular recognition site; other site
1429244001222	dimerization interface [polypeptide binding]; other site
1429244001223	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1429244001224	DNA binding site [nucleotide binding]
1429244001225	maltodextrin glucosidase; Provisional; Region: PRK10785
1429244001226	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1429244001227	homodimer interface [polypeptide binding]; other site
1429244001228	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1429244001229	active site
1429244001230	homodimer interface [polypeptide binding]; other site
1429244001231	catalytic site [active]
1429244001232	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1429244001233	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244001234	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001235	active site
1429244001236	phosphorylation site [posttranslational modification]
1429244001237	intermolecular recognition site; other site
1429244001238	dimerization interface [polypeptide binding]; other site
1429244001239	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244001240	DNA binding site [nucleotide binding]
1429244001241	HAMP domain; Region: HAMP; pfam00672
1429244001242	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244001243	dimerization interface [polypeptide binding]; other site
1429244001244	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244001245	dimer interface [polypeptide binding]; other site
1429244001246	phosphorylation site [posttranslational modification]
1429244001247	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001248	ATP binding site [chemical binding]; other site
1429244001249	Mg2+ binding site [ion binding]; other site
1429244001250	G-X-G motif; other site
1429244001251	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244001252	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
1429244001253	Walker A/P-loop; other site
1429244001254	ATP binding site [chemical binding]; other site
1429244001255	Q-loop/lid; other site
1429244001256	ABC transporter signature motif; other site
1429244001257	Walker B; other site
1429244001258	D-loop; other site
1429244001259	H-loop/switch region; other site
1429244001260	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
1429244001261	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244001262	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
1429244001263	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244001264	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
1429244001265	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1429244001266	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244001267	NAD binding site [chemical binding]; other site
1429244001268	dimer interface [polypeptide binding]; other site
1429244001269	substrate binding site [chemical binding]; other site
1429244001270	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244001271	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1429244001272	DNA binding residues [nucleotide binding]
1429244001273	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1429244001274	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1429244001275	active site
1429244001276	ATP binding site [chemical binding]; other site
1429244001277	substrate binding site [chemical binding]; other site
1429244001278	activation loop (A-loop); other site
1429244001279	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
1429244001280	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
1429244001281	N- and C-terminal domain interface [polypeptide binding]; other site
1429244001282	active site
1429244001283	catalytic site [active]
1429244001284	metal binding site [ion binding]; metal-binding site
1429244001285	carbohydrate binding site [chemical binding]; other site
1429244001286	ATP binding site [chemical binding]; other site
1429244001287	GntP family permease; Region: GntP_permease; pfam02447
1429244001288	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1429244001289	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1429244001290	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244001291	DNA-binding site [nucleotide binding]; DNA binding site
1429244001292	FCD domain; Region: FCD; pfam07729
1429244001293	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1429244001294	active site
1429244001295	Protein of unknown function (DUF1453); Region: DUF1453; pfam07301
1429244001296	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
1429244001297	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1429244001298	dimer interface [polypeptide binding]; other site
1429244001299	FMN binding site [chemical binding]; other site
1429244001300	Predicted integral membrane protein [Function unknown]; Region: COG0392
1429244001301	Uncharacterized conserved protein [Function unknown]; Region: COG2898
1429244001302	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1429244001303	Predicted ATPase [General function prediction only]; Region: COG3910
1429244001304	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244001305	Walker A/P-loop; other site
1429244001306	ATP binding site [chemical binding]; other site
1429244001307	Q-loop/lid; other site
1429244001308	ABC transporter signature motif; other site
1429244001309	Walker B; other site
1429244001310	D-loop; other site
1429244001311	H-loop/switch region; other site
1429244001312	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001313	putative substrate translocation pore; other site
1429244001314	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244001315	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1429244001316	Predicted transcriptional regulator [Transcription]; Region: COG4189
1429244001317	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244001318	putative DNA binding site [nucleotide binding]; other site
1429244001319	dimerization interface [polypeptide binding]; other site
1429244001320	putative Zn2+ binding site [ion binding]; other site
1429244001321	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1429244001322	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1429244001323	NAD binding site [chemical binding]; other site
1429244001324	putative active site [active]
1429244001325	substrate binding site [chemical binding]; other site
1429244001326	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1429244001327	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1429244001328	putative substrate binding site [chemical binding]; other site
1429244001329	putative ATP binding site [chemical binding]; other site
1429244001330	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1429244001331	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244001332	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1429244001333	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244001334	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244001335	dimer interface [polypeptide binding]; other site
1429244001336	putative CheW interface [polypeptide binding]; other site
1429244001337	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1429244001338	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1429244001339	dimer interface [polypeptide binding]; other site
1429244001340	putative radical transfer pathway; other site
1429244001341	diiron center [ion binding]; other site
1429244001342	tyrosyl radical; other site
1429244001343	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09209
1429244001344	ATP cone domain; Region: ATP-cone; pfam03477
1429244001345	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
1429244001346	Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867
1429244001347	Domain of unknown function DUF77; Region: DUF77; pfam01910
1429244001348	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244001349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001350	putative substrate translocation pore; other site
1429244001351	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244001352	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
1429244001353	DNA binding residues [nucleotide binding]
1429244001354	drug binding residues [chemical binding]; other site
1429244001355	dimer interface [polypeptide binding]; other site
1429244001356	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1429244001357	Protein of unknown function (DUF3231); Region: DUF3231; pfam11553
1429244001358	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244001359	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1429244001360	active site
1429244001361	SPRY domain-like in bacteria; Region: SPRY_like; cd12886
1429244001362	SPRY domain-like in bacteria; Region: SPRY_like; cd12886
1429244001363	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
1429244001364	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
1429244001365	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1429244001366	Acyl transferase domain; Region: Acyl_transf_1; cl08282
1429244001367	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1429244001368	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244001369	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244001370	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1429244001371	active site
1429244001372	NTP binding site [chemical binding]; other site
1429244001373	metal binding triad [ion binding]; metal-binding site
1429244001374	Dienelactone hydrolase family; Region: DLH; pfam01738
1429244001375	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244001376	dimerization interface [polypeptide binding]; other site
1429244001377	putative DNA binding site [nucleotide binding]; other site
1429244001378	putative Zn2+ binding site [ion binding]; other site
1429244001379	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1429244001380	O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK08248
1429244001381	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1429244001382	homodimer interface [polypeptide binding]; other site
1429244001383	substrate-cofactor binding pocket; other site
1429244001384	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244001385	catalytic residue [active]
1429244001386	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
1429244001387	active site residue [active]
1429244001388	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1429244001389	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244001390	dimerization interface [polypeptide binding]; other site
1429244001391	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1429244001392	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244001393	Zn2+ binding site [ion binding]; other site
1429244001394	Mg2+ binding site [ion binding]; other site
1429244001395	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1429244001396	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244001397	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244001398	dimer interface [polypeptide binding]; other site
1429244001399	phosphorylation site [posttranslational modification]
1429244001400	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001401	ATP binding site [chemical binding]; other site
1429244001402	Mg2+ binding site [ion binding]; other site
1429244001403	G-X-G motif; other site
1429244001404	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1429244001405	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1429244001406	NAD binding site [chemical binding]; other site
1429244001407	active site
1429244001408	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1429244001409	homotrimer interaction site [polypeptide binding]; other site
1429244001410	putative active site [active]
1429244001411	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed; Region: PRK12446
1429244001412	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1429244001413	active site
1429244001414	homodimer interface [polypeptide binding]; other site
1429244001415	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1429244001416	Sodium Bile acid symporter family; Region: SBF; pfam01758
1429244001417	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244001418	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1429244001419	putative active site [active]
1429244001420	putative FMN binding site [chemical binding]; other site
1429244001421	putative substrate binding site [chemical binding]; other site
1429244001422	putative catalytic residue [active]
1429244001423	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244001424	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244001425	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244001426	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001427	active site
1429244001428	phosphorylation site [posttranslational modification]
1429244001429	intermolecular recognition site; other site
1429244001430	dimerization interface [polypeptide binding]; other site
1429244001431	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244001432	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001433	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001434	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244001435	Cache domain; Region: Cache_1; pfam02743
1429244001436	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244001437	dimerization interface [polypeptide binding]; other site
1429244001438	Histidine kinase; Region: His_kinase; pfam06580
1429244001439	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001440	ATP binding site [chemical binding]; other site
1429244001441	Mg2+ binding site [ion binding]; other site
1429244001442	G-X-G motif; other site
1429244001443	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244001444	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001445	dimer interface [polypeptide binding]; other site
1429244001446	conserved gate region; other site
1429244001447	putative PBP binding loops; other site
1429244001448	ABC-ATPase subunit interface; other site
1429244001449	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244001450	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001451	dimer interface [polypeptide binding]; other site
1429244001452	conserved gate region; other site
1429244001453	putative PBP binding loops; other site
1429244001454	ABC-ATPase subunit interface; other site
1429244001455	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244001456	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244001457	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cl17426
1429244001458	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1429244001459	folate binding site [chemical binding]; other site
1429244001460	NADP+ binding site [chemical binding]; other site
1429244001461	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244001462	HTH domain; Region: HTH_11; pfam08279
1429244001463	WYL domain; Region: WYL; pfam13280
1429244001464	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
1429244001465	SNF2 Helicase protein; Region: DUF3670; pfam12419
1429244001466	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244001467	ATP binding site [chemical binding]; other site
1429244001468	putative Mg++ binding site [ion binding]; other site
1429244001469	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244001470	nucleotide binding region [chemical binding]; other site
1429244001471	ATP-binding site [chemical binding]; other site
1429244001472	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1429244001473	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1429244001474	Glutathionylspermidine synthase preATP-grasp; Region: GSP_synth; cl00503
1429244001475	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1429244001476	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1429244001477	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244001478	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244001479	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244001480	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1429244001481	putative NADH binding site [chemical binding]; other site
1429244001482	putative active site [active]
1429244001483	nudix motif; other site
1429244001484	putative metal binding site [ion binding]; other site
1429244001485	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001486	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244001487	putative substrate translocation pore; other site
1429244001488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001489	MarR family; Region: MarR_2; pfam12802
1429244001490	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244001491	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244001492	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244001493	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001494	putative substrate translocation pore; other site
1429244001495	Protein of unknown function (DUF3995); Region: DUF3995; pfam13160
1429244001496	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244001497	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244001498	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1429244001499	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1429244001500	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1429244001501	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1429244001502	active site
1429244001503	dimer interface [polypeptide binding]; other site
1429244001504	motif 1; other site
1429244001505	motif 2; other site
1429244001506	motif 3; other site
1429244001507	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1429244001508	anticodon binding site; other site
1429244001509	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1429244001510	synthetase active site [active]
1429244001511	NTP binding site [chemical binding]; other site
1429244001512	metal binding site [ion binding]; metal-binding site
1429244001513	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1429244001514	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1429244001515	classical (c) SDRs; Region: SDR_c; cd05233
1429244001516	NAD(P) binding site [chemical binding]; other site
1429244001517	active site
1429244001518	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1429244001519	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244001520	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244001521	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001522	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001523	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1429244001524	Melibiase; Region: Melibiase; pfam02065
1429244001525	Cupin domain; Region: Cupin_2; pfam07883
1429244001526	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244001527	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001528	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1429244001529	EamA-like transporter family; Region: EamA; pfam00892
1429244001530	EamA-like transporter family; Region: EamA; pfam00892
1429244001531	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1429244001532	dimer interface [polypeptide binding]; other site
1429244001533	putative tRNA-binding site [nucleotide binding]; other site
1429244001534	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1429244001535	Part of AAA domain; Region: AAA_19; pfam13245
1429244001536	Family description; Region: UvrD_C_2; pfam13538
1429244001537	Cold-inducible protein YdjO; Region: YdjO; pfam14169
1429244001538	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1429244001539	Predicted transcriptional regulators [Transcription]; Region: COG1378
1429244001540	Sugar-specific transcriptional regulator TrmB; Region: TrmB; pfam01978
1429244001541	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1429244001542	putative active site [active]
1429244001543	catalytic site [active]
1429244001544	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1429244001545	nudix motif; other site
1429244001546	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1429244001547	catalytic core [active]
1429244001548	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
1429244001549	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1429244001550	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1429244001551	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1429244001552	RNA polymerase sigma-70 factor, TIGR02957 family; Region: SigX4
1429244001553	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244001554	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1429244001555	DNA binding residues [nucleotide binding]
1429244001556	Predicted membrane protein [Function unknown]; Region: COG4818
1429244001557	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
1429244001558	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
1429244001559	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1429244001560	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244001561	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244001562	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1429244001563	active site
1429244001564	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244001565	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244001566	Coenzyme A binding pocket [chemical binding]; other site
1429244001567	Uncharacterized conserved protein [Function unknown]; Region: COG2461
1429244001568	Family of unknown function (DUF438); Region: DUF438; pfam04282
1429244001569	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
1429244001570	Domain of unknown function (DUF1858); Region: DUF1858; pfam08984
1429244001571	Predicted transcriptional regulators [Transcription]; Region: COG1725
1429244001572	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244001573	DNA-binding site [nucleotide binding]; DNA binding site
1429244001574	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244001575	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1429244001576	Walker A/P-loop; other site
1429244001577	ATP binding site [chemical binding]; other site
1429244001578	Q-loop/lid; other site
1429244001579	ABC transporter signature motif; other site
1429244001580	Walker B; other site
1429244001581	D-loop; other site
1429244001582	H-loop/switch region; other site
1429244001583	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1429244001584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244001585	Walker A/P-loop; other site
1429244001586	ATP binding site [chemical binding]; other site
1429244001587	Q-loop/lid; other site
1429244001588	ABC transporter signature motif; other site
1429244001589	Walker B; other site
1429244001590	D-loop; other site
1429244001591	H-loop/switch region; other site
1429244001592	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1429244001593	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1429244001594	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1429244001595	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001596	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244001597	putative substrate translocation pore; other site
1429244001598	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244001599	Coenzyme A binding pocket [chemical binding]; other site
1429244001600	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244001601	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244001602	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244001603	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244001604	dimerization interface [polypeptide binding]; other site
1429244001605	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244001606	non-specific DNA binding site [nucleotide binding]; other site
1429244001607	salt bridge; other site
1429244001608	sequence-specific DNA binding site [nucleotide binding]; other site
1429244001609	Predicted ATPase [General function prediction only]; Region: COG3903
1429244001610	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1429244001611	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1429244001612	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1429244001613	azoreductase; Reviewed; Region: PRK00170
1429244001614	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244001615	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1429244001616	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1429244001617	metal-dependent hydrolase; Provisional; Region: PRK00685
1429244001618	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1429244001619	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06501
1429244001620	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244001621	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001622	active site
1429244001623	phosphorylation site [posttranslational modification]
1429244001624	intermolecular recognition site; other site
1429244001625	dimerization interface [polypeptide binding]; other site
1429244001626	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244001627	DNA binding site [nucleotide binding]
1429244001628	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244001629	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244001630	dimerization interface [polypeptide binding]; other site
1429244001631	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244001632	dimer interface [polypeptide binding]; other site
1429244001633	phosphorylation site [posttranslational modification]
1429244001634	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001635	ATP binding site [chemical binding]; other site
1429244001636	Mg2+ binding site [ion binding]; other site
1429244001637	G-X-G motif; other site
1429244001638	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1429244001639	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1429244001640	catalytic triad [active]
1429244001641	catalytic triad [active]
1429244001642	oxyanion hole [active]
1429244001643	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1429244001644	catalytic triad [active]
1429244001645	catalytic triad [active]
1429244001646	oxyanion hole [active]
1429244001647	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_7; cd06244
1429244001648	putative active site [active]
1429244001649	Zn binding site [ion binding]; other site
1429244001650	Predicted membrane protein [Function unknown]; Region: COG2311
1429244001651	Protein of unknown function (DUF418); Region: DUF418; pfam04235
1429244001652	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244001653	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244001654	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244001655	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244001656	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244001657	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244001658	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244001659	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244001660	intersubunit interface [polypeptide binding]; other site
1429244001661	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244001662	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001663	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244001664	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244001665	intersubunit interface [polypeptide binding]; other site
1429244001666	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244001667	MarR family; Region: MarR_2; pfam12802
1429244001668	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1429244001669	Sodium Bile acid symporter family; Region: SBF; cl17470
1429244001670	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244001671	Helix-turn-helix domain; Region: HTH_18; pfam12833
1429244001672	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001673	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244001674	binding surface
1429244001675	TPR motif; other site
1429244001676	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1429244001677	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244001678	binding surface
1429244001679	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1429244001680	TPR motif; other site
1429244001681	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1429244001682	binding surface
1429244001683	TPR motif; other site
1429244001684	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244001685	TPR motif; other site
1429244001686	TPR repeat; Region: TPR_11; pfam13414
1429244001687	binding surface
1429244001688	Sugar-binding cellulase-like; Region: Cellulase-like; pfam12876
1429244001689	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
1429244001690	Beta-galactosidase, domain 2; Region: BetaGal_dom2; smart01029
1429244001691	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1429244001692	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); Region: NT5C; cl17836
1429244001693	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1429244001694	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1429244001695	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1429244001696	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1429244001697	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1429244001698	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001699	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244001700	putative substrate translocation pore; other site
1429244001701	maltose O-acetyltransferase; Provisional; Region: PRK10092
1429244001702	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1429244001703	active site
1429244001704	substrate binding site [chemical binding]; other site
1429244001705	trimer interface [polypeptide binding]; other site
1429244001706	CoA binding site [chemical binding]; other site
1429244001707	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1429244001708	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244001709	non-specific DNA binding site [nucleotide binding]; other site
1429244001710	salt bridge; other site
1429244001711	sequence-specific DNA binding site [nucleotide binding]; other site
1429244001712	Cupin domain; Region: Cupin_2; pfam07883
1429244001713	LysE type translocator; Region: LysE; cl00565
1429244001714	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1429244001715	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1429244001716	Ca binding site [ion binding]; other site
1429244001717	active site
1429244001718	catalytic site [active]
1429244001719	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
1429244001720	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244001721	active site turn [active]
1429244001722	phosphorylation site [posttranslational modification]
1429244001723	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244001724	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244001725	HPr interaction site; other site
1429244001726	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244001727	active site
1429244001728	phosphorylation site [posttranslational modification]
1429244001729	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244001730	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
1429244001731	DNA-binding site [nucleotide binding]; DNA binding site
1429244001732	UTRA domain; Region: UTRA; pfam07702
1429244001733	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1429244001734	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001735	active site
1429244001736	phosphorylation site [posttranslational modification]
1429244001737	intermolecular recognition site; other site
1429244001738	dimerization interface [polypeptide binding]; other site
1429244001739	LytTr DNA-binding domain; Region: LytTR; pfam04397
1429244001740	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1429244001741	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244001742	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244001743	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244001744	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244001745	Spore germination protein; Region: Spore_permease; cl17796
1429244001746	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244001747	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244001748	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244001749	DNA binding site [nucleotide binding]
1429244001750	domain linker motif; other site
1429244001751	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244001752	dimerization interface [polypeptide binding]; other site
1429244001753	ligand binding site [chemical binding]; other site
1429244001754	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1429244001755	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1429244001756	substrate binding site [chemical binding]; other site
1429244001757	hexamer interface [polypeptide binding]; other site
1429244001758	metal binding site [ion binding]; metal-binding site
1429244001759	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1429244001760	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1429244001761	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244001762	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244001763	active site turn [active]
1429244001764	phosphorylation site [posttranslational modification]
1429244001765	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244001766	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1429244001767	HPr interaction site; other site
1429244001768	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244001769	active site
1429244001770	phosphorylation site [posttranslational modification]
1429244001771	NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251
1429244001772	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244001773	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1429244001774	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1429244001775	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1429244001776	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1429244001777	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1429244001778	iron-sulfur cluster [ion binding]; other site
1429244001779	[2Fe-2S] cluster binding site [ion binding]; other site
1429244001780	BclB C-terminal domain; Region: exospore_TM; TIGR03721
1429244001781	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1429244001782	sugar binding site [chemical binding]; other site
1429244001783	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244001784	Interdomain contacts; other site
1429244001785	Cytokine receptor motif; other site
1429244001786	S-layer homology domain; Region: SLH; pfam00395
1429244001787	S-layer homology domain; Region: SLH; pfam00395
1429244001788	S-layer homology domain; Region: SLH; pfam00395
1429244001789	Phage Tail Collar Domain; Region: Collar; pfam07484
1429244001790	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244001791	Spore germination protein; Region: Spore_permease; pfam03845
1429244001792	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244001793	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244001794	Predicted transcriptional regulators [Transcription]; Region: COG1695
1429244001795	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1429244001796	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1429244001797	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; cl01382
1429244001798	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244001799	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244001800	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1429244001801	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244001802	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001803	active site
1429244001804	phosphorylation site [posttranslational modification]
1429244001805	intermolecular recognition site; other site
1429244001806	dimerization interface [polypeptide binding]; other site
1429244001807	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244001808	DNA binding site [nucleotide binding]
1429244001809	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244001810	dimerization interface [polypeptide binding]; other site
1429244001811	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244001812	dimer interface [polypeptide binding]; other site
1429244001813	phosphorylation site [posttranslational modification]
1429244001814	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001815	ATP binding site [chemical binding]; other site
1429244001816	Mg2+ binding site [ion binding]; other site
1429244001817	G-X-G motif; other site
1429244001818	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1429244001819	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1429244001820	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1429244001821	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1429244001822	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1429244001823	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1429244001824	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244001825	Predicted flavoprotein [General function prediction only]; Region: COG0431
1429244001826	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1429244001827	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1429244001828	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1429244001829	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1429244001830	oligomerization interface [polypeptide binding]; other site
1429244001831	active site
1429244001832	metal binding site [ion binding]; metal-binding site
1429244001833	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1429244001834	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1429244001835	dimer interface [polypeptide binding]; other site
1429244001836	FMN binding site [chemical binding]; other site
1429244001837	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1429244001838	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244001839	Zn binding site [ion binding]; other site
1429244001840	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1429244001841	Zn binding site [ion binding]; other site
1429244001842	SWIM zinc finger; Region: SWIM; pfam04434
1429244001843	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
1429244001844	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
1429244001845	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244001846	ATP binding site [chemical binding]; other site
1429244001847	putative Mg++ binding site [ion binding]; other site
1429244001848	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244001849	nucleotide binding region [chemical binding]; other site
1429244001850	ATP-binding site [chemical binding]; other site
1429244001851	Macrolide 2'-Phosphotransferase (MPH2'). MPH2' is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase; Region: MPH2' cd05152
1429244001852	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244001853	putative active site [active]
1429244001854	putative substrate binding site [chemical binding]; other site
1429244001855	ATP binding site [chemical binding]; other site
1429244001856	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_2; cd06160
1429244001857	Peptidase family M50; Region: Peptidase_M50; pfam02163
1429244001858	active site
1429244001859	putative substrate binding region [chemical binding]; other site
1429244001860	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244001861	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001862	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244001863	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001864	MFS/sugar transport protein; Region: MFS_2; pfam13347
1429244001865	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001866	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1429244001867	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1429244001868	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1429244001869	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244001870	HAMP domain; Region: HAMP; pfam00672
1429244001871	Histidine kinase; Region: His_kinase; pfam06580
1429244001872	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244001873	ATP binding site [chemical binding]; other site
1429244001874	Mg2+ binding site [ion binding]; other site
1429244001875	G-X-G motif; other site
1429244001876	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244001877	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244001878	active site
1429244001879	phosphorylation site [posttranslational modification]
1429244001880	intermolecular recognition site; other site
1429244001881	dimerization interface [polypeptide binding]; other site
1429244001882	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001883	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244001884	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244001885	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244001886	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244001887	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001888	dimer interface [polypeptide binding]; other site
1429244001889	conserved gate region; other site
1429244001890	putative PBP binding loops; other site
1429244001891	ABC-ATPase subunit interface; other site
1429244001892	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244001893	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244001894	dimer interface [polypeptide binding]; other site
1429244001895	conserved gate region; other site
1429244001896	putative PBP binding loops; other site
1429244001897	ABC-ATPase subunit interface; other site
1429244001898	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1429244001899	metal coordination site [ion binding]; other site
1429244001900	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1429244001901	calcium mediated ligand binding site; other site
1429244001902	intermolecular salt bridges; other site
1429244001903	chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; Region: chaperonin_like; cl02777
1429244001904	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244001905	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244001906	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244001907	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1429244001908	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244001909	DNA-binding site [nucleotide binding]; DNA binding site
1429244001910	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244001911	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244001912	homodimer interface [polypeptide binding]; other site
1429244001913	catalytic residue [active]
1429244001914	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900
1429244001915	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244001916	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244001917	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244001918	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1429244001919	DNA binding residues [nucleotide binding]
1429244001920	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244001921	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001922	putative substrate translocation pore; other site
1429244001923	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1429244001924	Ligand Binding Site [chemical binding]; other site
1429244001925	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1429244001926	Uncharacterized ALDH (y4uC) with similarity to Tortula ruralis aldehyde dehydrogenase ALDH21A1; Region: ALDH_y4uC; cd07149
1429244001927	NAD(P) binding site [chemical binding]; other site
1429244001928	catalytic residues [active]
1429244001929	short chain dehydrogenase; Provisional; Region: PRK06523
1429244001930	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244001931	NAD(P) binding site [chemical binding]; other site
1429244001932	active site
1429244001933	SnoaL-like domain; Region: SnoaL_2; pfam12680
1429244001934	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244001935	HTH domain; Region: HTH_11; pfam08279
1429244001936	WYL domain; Region: WYL; pfam13280
1429244001937	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1429244001938	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244001939	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1429244001940	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1429244001941	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244001942	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1429244001943	DNA binding residues [nucleotide binding]
1429244001944	putative dimer interface [polypeptide binding]; other site
1429244001945	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1429244001946	phosphate binding site [ion binding]; other site
1429244001947	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1429244001948	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244001949	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244001950	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
1429244001951	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244001952	DNA binding residues [nucleotide binding]
1429244001953	dimer interface [polypeptide binding]; other site
1429244001954	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1429244001955	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1429244001956	GAF domain; Region: GAF_2; pfam13185
1429244001957	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244001958	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244001959	Cobalt transport protein; Region: CbiQ; cl00463
1429244001960	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; cl01943
1429244001961	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1429244001962	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1429244001963	Walker A/P-loop; other site
1429244001964	ATP binding site [chemical binding]; other site
1429244001965	Q-loop/lid; other site
1429244001966	ABC transporter signature motif; other site
1429244001967	Walker B; other site
1429244001968	D-loop; other site
1429244001969	H-loop/switch region; other site
1429244001970	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1429244001971	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1429244001972	Walker A/P-loop; other site
1429244001973	ATP binding site [chemical binding]; other site
1429244001974	Q-loop/lid; other site
1429244001975	ABC transporter signature motif; other site
1429244001976	Walker B; other site
1429244001977	D-loop; other site
1429244001978	H-loop/switch region; other site
1429244001979	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244001980	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244001981	putative substrate translocation pore; other site
1429244001982	Levansucrase/Invertase; Region: Glyco_hydro_68; pfam02435
1429244001983	active site
1429244001984	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1429244001985	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244001986	substrate binding [chemical binding]; other site
1429244001987	active site
1429244001988	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244001989	MarR family; Region: MarR_2; cl17246
1429244001990	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244001991	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1429244001992	LysE type translocator; Region: LysE; pfam01810
1429244001993	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1429244001994	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1429244001995	putative active site [active]
1429244001996	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1429244001997	dimer interface [polypeptide binding]; other site
1429244001998	active site
1429244001999	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1429244002000	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1429244002001	substrate binding site [chemical binding]; other site
1429244002002	ATP binding site [chemical binding]; other site
1429244002003	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1429244002004	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244002005	DNA-binding site [nucleotide binding]; DNA binding site
1429244002006	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1429244002007	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1429244002008	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244002009	active site
1429244002010	Predicted membrane protein [Function unknown]; Region: COG1288
1429244002011	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1429244002012	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1429244002013	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244002014	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1429244002015	PAS fold; Region: PAS_4; pfam08448
1429244002016	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244002017	dimer interface [polypeptide binding]; other site
1429244002018	phosphorylation site [posttranslational modification]
1429244002019	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244002020	ATP binding site [chemical binding]; other site
1429244002021	Mg2+ binding site [ion binding]; other site
1429244002022	G-X-G motif; other site
1429244002023	bacillithiol system oxidoreductase, YphP/YqiW family; Region: YphP_YqiW; TIGR04191
1429244002024	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1429244002025	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1429244002026	homodimer interface [polypeptide binding]; other site
1429244002027	NAD binding pocket [chemical binding]; other site
1429244002028	ATP binding pocket [chemical binding]; other site
1429244002029	Mg binding site [ion binding]; other site
1429244002030	active-site loop [active]
1429244002031	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1429244002032	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1429244002033	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
1429244002034	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1429244002035	minor groove reading motif; other site
1429244002036	helix-hairpin-helix signature motif; other site
1429244002037	substrate binding pocket [chemical binding]; other site
1429244002038	active site
1429244002039	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1429244002040	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1429244002041	DNA binding and oxoG recognition site [nucleotide binding]
1429244002042	Esterase/lipase [General function prediction only]; Region: COG1647
1429244002043	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1429244002044	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1429244002045	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1429244002046	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1429244002047	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1429244002048	putative deacylase active site [active]
1429244002049	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1429244002050	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244002051	non-specific DNA binding site [nucleotide binding]; other site
1429244002052	salt bridge; other site
1429244002053	sequence-specific DNA binding site [nucleotide binding]; other site
1429244002054	Cupin domain; Region: Cupin_2; pfam07883
1429244002055	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1429244002056	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1429244002057	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1429244002058	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244002059	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244002060	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244002061	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244002062	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1429244002063	Melibiase; Region: Melibiase; pfam02065
1429244002064	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1429244002065	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244002066	active site turn [active]
1429244002067	phosphorylation site [posttranslational modification]
1429244002068	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244002069	DinB family; Region: DinB; cl17821
1429244002070	DinB superfamily; Region: DinB_2; pfam12867
1429244002071	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1429244002072	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1429244002073	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1429244002074	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244002075	Coenzyme A binding pocket [chemical binding]; other site
1429244002076	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1429244002077	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1429244002078	Catalytic site [active]
1429244002079	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1429244002080	RNA/DNA hybrid binding site [nucleotide binding]; other site
1429244002081	active site
1429244002082	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1429244002083	DNA binding site [nucleotide binding]
1429244002084	active site
1429244002085	Domain of unknown function (DUF3552); Region: DUF3552; pfam12072
1429244002086	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1429244002087	homodecamer interface [polypeptide binding]; other site
1429244002088	GTP cyclohydrolase I; Provisional; Region: PLN03044
1429244002089	active site
1429244002090	putative catalytic site residues [active]
1429244002091	zinc binding site [ion binding]; other site
1429244002092	GTP-CH-I/GFRP interaction surface; other site
1429244002093	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1429244002094	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1429244002095	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1429244002096	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1429244002097	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1429244002098	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1429244002099	nucleophilic elbow; other site
1429244002100	catalytic triad; other site
1429244002101	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1429244002102	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1429244002103	Bacterial transcriptional regulator; Region: IclR; pfam01614
1429244002104	ThiC-associated domain; Region: ThiC-associated; pfam13667
1429244002105	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1429244002106	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1429244002107	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1429244002108	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1429244002109	aconitate hydratase; Validated; Region: PRK09277
1429244002110	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1429244002111	substrate binding site [chemical binding]; other site
1429244002112	ligand binding site [chemical binding]; other site
1429244002113	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1429244002114	substrate binding site [chemical binding]; other site
1429244002115	Putative amidase domain; Region: Amidase_6; pfam12671
1429244002116	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1429244002117	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1429244002118	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1429244002119	putative UV damage endonuclease; Provisional; Region: uvsE; PRK02308
1429244002120	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1429244002121	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1429244002122	active site
1429244002123	dimerization interface [polypeptide binding]; other site
1429244002124	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244002125	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244002126	dimerization interface [polypeptide binding]; other site
1429244002127	Histidine kinase; Region: His_kinase; pfam06580
1429244002128	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244002129	ATP binding site [chemical binding]; other site
1429244002130	Mg2+ binding site [ion binding]; other site
1429244002131	G-X-G motif; other site
1429244002132	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
1429244002133	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244002134	active site
1429244002135	phosphorylation site [posttranslational modification]
1429244002136	intermolecular recognition site; other site
1429244002137	dimerization interface [polypeptide binding]; other site
1429244002138	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244002139	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244002140	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244002141	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002142	dimer interface [polypeptide binding]; other site
1429244002143	conserved gate region; other site
1429244002144	putative PBP binding loops; other site
1429244002145	ABC-ATPase subunit interface; other site
1429244002146	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244002147	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002148	dimer interface [polypeptide binding]; other site
1429244002149	conserved gate region; other site
1429244002150	putative PBP binding loops; other site
1429244002151	ABC-ATPase subunit interface; other site
1429244002152	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1429244002153	active site
1429244002154	catalytic triad [active]
1429244002155	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1429244002156	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
1429244002157	active site
1429244002158	zinc binding site [ion binding]; other site
1429244002159	Anabaena sensory rhodopsin transducer; Region: ASRT; pfam07100
1429244002160	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1429244002161	EamA-like transporter family; Region: EamA; pfam00892
1429244002162	EamA-like transporter family; Region: EamA; pfam00892
1429244002163	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK12389
1429244002164	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1429244002165	inhibitor-cofactor binding pocket; inhibition site
1429244002166	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244002167	catalytic residue [active]
1429244002168	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1429244002169	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586
1429244002170	ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; Region: ABC_NatA_like; cd03267
1429244002171	Walker A/P-loop; other site
1429244002172	ATP binding site [chemical binding]; other site
1429244002173	Q-loop/lid; other site
1429244002174	ABC transporter signature motif; other site
1429244002175	Walker B; other site
1429244002176	D-loop; other site
1429244002177	H-loop/switch region; other site
1429244002178	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587
1429244002179	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
1429244002180	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
1429244002181	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1429244002182	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1429244002183	catalytic triad [active]
1429244002184	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244002185	H+ Antiporter protein; Region: 2A0121; TIGR00900
1429244002186	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244002187	putative substrate translocation pore; other site
1429244002188	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1429244002189	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1429244002190	GMP synthase; Reviewed; Region: guaA; PRK00074
1429244002191	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1429244002192	AMP/PPi binding site [chemical binding]; other site
1429244002193	candidate oxyanion hole; other site
1429244002194	catalytic triad [active]
1429244002195	potential glutamine specificity residues [chemical binding]; other site
1429244002196	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1429244002197	ATP Binding subdomain [chemical binding]; other site
1429244002198	Ligand Binding sites [chemical binding]; other site
1429244002199	Dimerization subdomain; other site
1429244002200	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E_like proteins; Region: GAT1_Peptidase_E_like; cd03129
1429244002201	catalytic triad [active]
1429244002202	active site nucleophile [active]
1429244002203	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244002204	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244002205	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244002206	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244002207	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1429244002208	dimerization interface [polypeptide binding]; other site
1429244002209	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
1429244002210	active site
1429244002211	catalytic triad [active]
1429244002212	oxyanion hole [active]
1429244002213	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1429244002214	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1429244002215	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1429244002216	putative NAD(P) binding site [chemical binding]; other site
1429244002217	SnoaL-like domain; Region: SnoaL_2; pfam12680
1429244002218	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1429244002219	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK12879
1429244002220	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1429244002221	dimer interface [polypeptide binding]; other site
1429244002222	active site
1429244002223	CoA binding pocket [chemical binding]; other site
1429244002224	DNA topoisomerase III; Provisional; Region: PRK07726
1429244002225	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1429244002226	active site
1429244002227	putative interdomain interaction site [polypeptide binding]; other site
1429244002228	putative metal-binding site [ion binding]; other site
1429244002229	putative nucleotide binding site [chemical binding]; other site
1429244002230	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1429244002231	domain I; other site
1429244002232	DNA binding groove [nucleotide binding]
1429244002233	phosphate binding site [ion binding]; other site
1429244002234	domain II; other site
1429244002235	domain III; other site
1429244002236	nucleotide binding site [chemical binding]; other site
1429244002237	catalytic site [active]
1429244002238	domain IV; other site
1429244002239	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1429244002240	active site
1429244002241	homotetramer interface [polypeptide binding]; other site
1429244002242	homodimer interface [polypeptide binding]; other site
1429244002243	Protein of unknown function (DUF4023); Region: DUF4023; pfam13215
1429244002244	Protein of unknown function (DUF1294); Region: DUF1294; cl01311
1429244002245	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1429244002246	Ligand Binding Site [chemical binding]; other site
1429244002247	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1429244002248	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1429244002249	ATP-grasp domain; Region: ATP-grasp; pfam02222
1429244002250	adenylosuccinate lyase; Provisional; Region: PRK07492
1429244002251	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1429244002252	tetramer interface [polypeptide binding]; other site
1429244002253	active site
1429244002254	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1429244002255	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
1429244002256	ATP binding site [chemical binding]; other site
1429244002257	active site
1429244002258	substrate binding site [chemical binding]; other site
1429244002259	phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed; Region: PRK05974
1429244002260	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
1429244002261	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1429244002262	putative active site [active]
1429244002263	catalytic triad [active]
1429244002264	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
1429244002265	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1429244002266	dimerization interface [polypeptide binding]; other site
1429244002267	ATP binding site [chemical binding]; other site
1429244002268	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1429244002269	dimerization interface [polypeptide binding]; other site
1429244002270	ATP binding site [chemical binding]; other site
1429244002271	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
1429244002272	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1429244002273	active site
1429244002274	tetramer interface [polypeptide binding]; other site
1429244002275	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244002276	active site
1429244002277	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1429244002278	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1429244002279	dimerization interface [polypeptide binding]; other site
1429244002280	putative ATP binding site [chemical binding]; other site
1429244002281	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1429244002282	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1429244002283	active site
1429244002284	substrate binding site [chemical binding]; other site
1429244002285	cosubstrate binding site; other site
1429244002286	catalytic site [active]
1429244002287	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1429244002288	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1429244002289	purine monophosphate binding site [chemical binding]; other site
1429244002290	dimer interface [polypeptide binding]; other site
1429244002291	putative catalytic residues [active]
1429244002292	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1429244002293	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1429244002294	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1429244002295	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1429244002296	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1429244002297	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244002298	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244002299	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1429244002300	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244002301	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244002302	substrate binding pocket [chemical binding]; other site
1429244002303	membrane-bound complex binding site; other site
1429244002304	hinge residues; other site
1429244002305	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1429244002306	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002307	dimer interface [polypeptide binding]; other site
1429244002308	conserved gate region; other site
1429244002309	putative PBP binding loops; other site
1429244002310	ABC-ATPase subunit interface; other site
1429244002311	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244002312	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244002313	Walker A/P-loop; other site
1429244002314	ATP binding site [chemical binding]; other site
1429244002315	Q-loop/lid; other site
1429244002316	ABC transporter signature motif; other site
1429244002317	Walker B; other site
1429244002318	D-loop; other site
1429244002319	H-loop/switch region; other site
1429244002320	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1429244002321	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1429244002322	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1429244002323	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244002324	ABC-ATPase subunit  interface; other site
1429244002325	dimer interface [polypeptide binding]; other site
1429244002326	putative PBP binding regions; other site
1429244002327	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244002328	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244002329	ABC-ATPase subunit  interface; other site
1429244002330	dimer interface [polypeptide binding]; other site
1429244002331	putative PBP binding regions; other site
1429244002332	ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FecB; COG4594
1429244002333	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1429244002334	siderophore binding site; other site
1429244002335	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1429244002336	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244002337	active site
1429244002338	phosphorylation site [posttranslational modification]
1429244002339	intermolecular recognition site; other site
1429244002340	dimerization interface [polypeptide binding]; other site
1429244002341	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1429244002342	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1429244002343	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244002344	ATP binding site [chemical binding]; other site
1429244002345	Mg2+ binding site [ion binding]; other site
1429244002346	G-X-G motif; other site
1429244002347	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1429244002348	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244002349	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244002350	active site
1429244002351	catalytic tetrad [active]
1429244002352	Predicted integral membrane protein [Function unknown]; Region: COG5658
1429244002353	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
1429244002354	SdpI/YhfL protein family; Region: SdpI; pfam13630
1429244002355	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244002356	dimerization interface [polypeptide binding]; other site
1429244002357	putative DNA binding site [nucleotide binding]; other site
1429244002358	putative Zn2+ binding site [ion binding]; other site
1429244002359	Predicted esterase [General function prediction only]; Region: COG0400
1429244002360	small acid-soluble spore protein Tlp; Provisional; Region: PRK03830
1429244002361	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244002362	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244002363	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002364	dimer interface [polypeptide binding]; other site
1429244002365	conserved gate region; other site
1429244002366	putative PBP binding loops; other site
1429244002367	ABC-ATPase subunit interface; other site
1429244002368	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244002369	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002370	dimer interface [polypeptide binding]; other site
1429244002371	conserved gate region; other site
1429244002372	putative PBP binding loops; other site
1429244002373	ABC-ATPase subunit interface; other site
1429244002374	threonine dehydratase; Validated; Region: PRK08639
1429244002375	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1429244002376	tetramer interface [polypeptide binding]; other site
1429244002377	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244002378	catalytic residue [active]
1429244002379	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1429244002380	putative Ile/Val binding site [chemical binding]; other site
1429244002381	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
1429244002382	substrate binding site [chemical binding]; other site
1429244002383	active site
1429244002384	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244002385	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244002386	ABC-ATPase subunit  interface; other site
1429244002387	dimer interface [polypeptide binding]; other site
1429244002388	putative PBP binding regions; other site
1429244002389	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1429244002390	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244002391	ABC-ATPase subunit  interface; other site
1429244002392	dimer interface [polypeptide binding]; other site
1429244002393	putative PBP binding regions; other site
1429244002394	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244002395	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244002396	intersubunit interface [polypeptide binding]; other site
1429244002397	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1429244002398	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244002399	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1429244002400	putative active site [active]
1429244002401	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1429244002402	metal binding site [ion binding]; metal-binding site
1429244002403	Protein of unknown function (DUF3048); Region: DUF3048; pfam11258
1429244002404	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
1429244002405	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1429244002406	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244002407	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244002408	substrate binding pocket [chemical binding]; other site
1429244002409	membrane-bound complex binding site; other site
1429244002410	hinge residues; other site
1429244002411	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1429244002412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002413	dimer interface [polypeptide binding]; other site
1429244002414	conserved gate region; other site
1429244002415	putative PBP binding loops; other site
1429244002416	ABC-ATPase subunit interface; other site
1429244002417	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244002418	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244002419	Walker A/P-loop; other site
1429244002420	ATP binding site [chemical binding]; other site
1429244002421	Q-loop/lid; other site
1429244002422	ABC transporter signature motif; other site
1429244002423	Walker B; other site
1429244002424	D-loop; other site
1429244002425	H-loop/switch region; other site
1429244002426	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244002427	Coenzyme A binding pocket [chemical binding]; other site
1429244002428	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1429244002429	Uncharacterized bacterial subfamily of the Thermotoga maritima CorA-like family; Region: TmCorA-like_u2; cd12831
1429244002430	oligomer interface [polypeptide binding]; other site
1429244002431	metal binding site [ion binding]; metal-binding site
1429244002432	metal binding site [ion binding]; metal-binding site
1429244002433	putative Cl binding site [ion binding]; other site
1429244002434	aspartate ring; other site
1429244002435	basic sphincter; other site
1429244002436	hydrophobic gate; other site
1429244002437	periplasmic entrance; other site
1429244002438	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4496
1429244002439	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
1429244002440	putative active site [active]
1429244002441	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
1429244002442	putative active site [active]
1429244002443	putative lipid kinase; Reviewed; Region: PRK13337
1429244002444	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1429244002445	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
1429244002446	23S rRNA (uracil-5-)-methyltransferase RumA; Region: rumA; TIGR00479
1429244002447	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244002448	S-adenosylmethionine binding site [chemical binding]; other site
1429244002449	Virulence protein [General function prediction only]; Region: COG3943
1429244002450	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1429244002451	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
1429244002452	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1429244002453	FMN binding site [chemical binding]; other site
1429244002454	active site
1429244002455	catalytic residues [active]
1429244002456	substrate binding site [chemical binding]; other site
1429244002457	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244002458	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244002459	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244002460	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1429244002461	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
1429244002462	active site
1429244002463	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244002464	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244002465	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244002466	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244002467	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1429244002468	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Region: TIGR02336
1429244002469	Lacto-N-biose phosphorylase; Region: Lact_bio_phlase; pfam09508
1429244002470	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244002471	HTH domain; Region: HTH_11; pfam08279
1429244002472	WYL domain; Region: WYL; pfam13280
1429244002473	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1429244002474	dimer interface [polypeptide binding]; other site
1429244002475	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1429244002476	hypothetical protein; Validated; Region: PRK00029
1429244002477	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
1429244002478	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244002479	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244002480	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244002481	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244002482	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244002483	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244002484	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733
1429244002485	short chain dehydrogenase; Provisional; Region: PRK06197
1429244002486	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244002487	NAD(P) binding site [chemical binding]; other site
1429244002488	active site
1429244002489	MarR family; Region: MarR; pfam01047
1429244002490	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1429244002491	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244002492	Coenzyme A binding pocket [chemical binding]; other site
1429244002493	putative transport protein YifK; Provisional; Region: PRK10746
1429244002494	Domain of unknown function (DUF1980); Region: DUF1980; cl01492
1429244002495	Protein of unknown function (DUF3953); Region: DUF3953; pfam13129
1429244002496	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1429244002497	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1429244002498	putative NAD(P) binding site [chemical binding]; other site
1429244002499	putative substrate binding site [chemical binding]; other site
1429244002500	catalytic Zn binding site [ion binding]; other site
1429244002501	structural Zn binding site [ion binding]; other site
1429244002502	dimer interface [polypeptide binding]; other site
1429244002503	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244002504	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1429244002505	DNA binding residues [nucleotide binding]
1429244002506	putative dimer interface [polypeptide binding]; other site
1429244002507	S-layer homology domain; Region: SLH; pfam00395
1429244002508	S-layer homology domain; Region: SLH; pfam00395
1429244002509	Domain of Unknown Function with PDB structure (DUF3863); Region: DUF3863; pfam12979
1429244002510	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1429244002511	dimer interface [polypeptide binding]; other site
1429244002512	FMN binding site [chemical binding]; other site
1429244002513	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244002514	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244002515	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244002516	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244002517	intersubunit interface [polypeptide binding]; other site
1429244002518	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
1429244002519	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
1429244002520	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1429244002521	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1429244002522	homodimer interface [polypeptide binding]; other site
1429244002523	NADP binding site [chemical binding]; other site
1429244002524	substrate binding site [chemical binding]; other site
1429244002525	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
1429244002526	The Delta12 Fatty Acid Desaturase (Delta12-FADS)-like CD includes the integral-membrane enzymes, delta-12 acyl-lipid desaturases, oleate 12-hydroxylases, omega3 and omega6 fatty acid desaturases, and other related proteins, found in a wide range of...; Region: Delta12-FADS-like; cd03507
1429244002527	putative di-iron ligands [ion binding]; other site
1429244002528	Predicted transcriptional regulators [Transcription]; Region: COG1695
1429244002529	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1429244002530	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
1429244002531	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1429244002532	Histidine kinase; Region: HisKA_3; pfam07730
1429244002533	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244002534	ATP binding site [chemical binding]; other site
1429244002535	Mg2+ binding site [ion binding]; other site
1429244002536	G-X-G motif; other site
1429244002537	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244002538	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244002539	active site
1429244002540	phosphorylation site [posttranslational modification]
1429244002541	intermolecular recognition site; other site
1429244002542	dimerization interface [polypeptide binding]; other site
1429244002543	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244002544	DNA binding residues [nucleotide binding]
1429244002545	dimerization interface [polypeptide binding]; other site
1429244002546	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1429244002547	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1429244002548	Substrate-binding site [chemical binding]; other site
1429244002549	Substrate specificity [chemical binding]; other site
1429244002550	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1429244002551	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1429244002552	Substrate-binding site [chemical binding]; other site
1429244002553	Substrate specificity [chemical binding]; other site
1429244002554	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244002555	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244002556	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1429244002557	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1429244002558	Walker A/P-loop; other site
1429244002559	ATP binding site [chemical binding]; other site
1429244002560	Q-loop/lid; other site
1429244002561	ABC transporter signature motif; other site
1429244002562	Walker B; other site
1429244002563	D-loop; other site
1429244002564	H-loop/switch region; other site
1429244002565	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1429244002566	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
1429244002567	dimer interface [polypeptide binding]; other site
1429244002568	conserved gate region; other site
1429244002569	ABC-ATPase subunit interface; other site
1429244002570	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1429244002571	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244002572	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
1429244002573	metal binding site [ion binding]; metal-binding site
1429244002574	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1429244002575	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1429244002576	active site
1429244002577	metal binding site [ion binding]; metal-binding site
1429244002578	Uncharacterized conserved protein [Function unknown]; Region: RtcB; COG1690
1429244002579	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
1429244002580	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1429244002581	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1429244002582	shikimate binding site; other site
1429244002583	NAD(P) binding site [chemical binding]; other site
1429244002584	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244002585	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244002586	putative substrate translocation pore; other site
1429244002587	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244002588	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244002589	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1429244002590	putative dimerization interface [polypeptide binding]; other site
1429244002591	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244002592	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244002593	putative substrate translocation pore; other site
1429244002594	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1429244002595	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1429244002596	active site
1429244002597	catalytic residue [active]
1429244002598	dimer interface [polypeptide binding]; other site
1429244002599	shikimate kinase; Reviewed; Region: aroK; PRK00131
1429244002600	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1429244002601	ADP binding site [chemical binding]; other site
1429244002602	magnesium binding site [ion binding]; other site
1429244002603	putative shikimate binding site; other site
1429244002604	Pectate lyase; Region: Pectate_lyase; pfam03211
1429244002605	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244002606	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1429244002607	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1429244002608	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244002609	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244002610	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244002611	putative substrate translocation pore; other site
1429244002612	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1429244002613	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1429244002614	dimer interface [polypeptide binding]; other site
1429244002615	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244002616	catalytic residue [active]
1429244002617	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244002618	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244002619	active site
1429244002620	catalytic tetrad [active]
1429244002621	WYL domain; Region: WYL; pfam13280
1429244002622	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244002623	WYL domain; Region: WYL; pfam13280
1429244002624	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1429244002625	RNA repair, ligase-Pnkp-associating, region of Hen1; Region: Hen1_L; pfam12623
1429244002626	3' terminal RNA ribose 2'-O-methyltransferase Hen1; Region: bacter_Hen1; TIGR04074
1429244002627	polynucleotide kinase-phosphatase; Region: bacter_Pnkp; TIGR04075
1429244002628	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1429244002629	G1 box; other site
1429244002630	GTP/Mg2+ binding site [chemical binding]; other site
1429244002631	Switch I region; other site
1429244002632	G3 box; other site
1429244002633	Switch II region; other site
1429244002634	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1429244002635	active site
1429244002636	metal binding site [ion binding]; metal-binding site
1429244002637	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1429244002638	active site
1429244002639	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
1429244002640	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1429244002641	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1429244002642	Walker A/P-loop; other site
1429244002643	ATP binding site [chemical binding]; other site
1429244002644	Q-loop/lid; other site
1429244002645	ABC transporter signature motif; other site
1429244002646	Walker B; other site
1429244002647	D-loop; other site
1429244002648	H-loop/switch region; other site
1429244002649	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1429244002650	Walker A/P-loop; other site
1429244002651	ATP binding site [chemical binding]; other site
1429244002652	Q-loop/lid; other site
1429244002653	ABC transporter signature motif; other site
1429244002654	Walker B; other site
1429244002655	D-loop; other site
1429244002656	H-loop/switch region; other site
1429244002657	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1429244002658	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1429244002659	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244002660	Walker A/P-loop; other site
1429244002661	ATP binding site [chemical binding]; other site
1429244002662	Q-loop/lid; other site
1429244002663	ABC transporter signature motif; other site
1429244002664	Walker B; other site
1429244002665	D-loop; other site
1429244002666	H-loop/switch region; other site
1429244002667	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002668	dimer interface [polypeptide binding]; other site
1429244002669	conserved gate region; other site
1429244002670	ABC-ATPase subunit interface; other site
1429244002671	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1429244002672	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1429244002673	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1429244002674	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244002675	Coenzyme A binding pocket [chemical binding]; other site
1429244002676	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244002677	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244002678	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244002679	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1429244002680	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1429244002681	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
1429244002682	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1429244002683	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1429244002684	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1429244002685	S-layer homology domain; Region: SLH; pfam00395
1429244002686	S-layer homology domain; Region: SLH; pfam00395
1429244002687	S-layer homology domain; Region: SLH; pfam00395
1429244002688	S-layer homology domain; Region: SLH; pfam00395
1429244002689	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
1429244002690	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
1429244002691	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244002692	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1429244002693	siderophore binding site; other site
1429244002694	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244002695	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244002696	ABC-ATPase subunit  interface; other site
1429244002697	dimer interface [polypeptide binding]; other site
1429244002698	putative PBP binding regions; other site
1429244002699	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1429244002700	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244002701	ABC-ATPase subunit  interface; other site
1429244002702	dimer interface [polypeptide binding]; other site
1429244002703	putative PBP binding regions; other site
1429244002704	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244002705	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244002706	Walker A/P-loop; other site
1429244002707	ATP binding site [chemical binding]; other site
1429244002708	Q-loop/lid; other site
1429244002709	ABC transporter signature motif; other site
1429244002710	Walker B; other site
1429244002711	D-loop; other site
1429244002712	H-loop/switch region; other site
1429244002713	siderophore-iron reductase FhuF; Region: Fe_III_red_FhuF; TIGR03951
1429244002714	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1429244002715	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1429244002716	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1429244002717	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1429244002718	IucA / IucC family; Region: IucA_IucC; pfam04183
1429244002719	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1429244002720	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1429244002721	IucA / IucC family; Region: IucA_IucC; pfam04183
1429244002722	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1429244002723	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1429244002724	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1429244002725	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme PvsE; Region: PLPDE_III_PvsE_like; cd06843
1429244002726	dimer interface [polypeptide binding]; other site
1429244002727	active site
1429244002728	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1429244002729	catalytic residues [active]
1429244002730	substrate binding site [chemical binding]; other site
1429244002731	IucA / IucC family; Region: IucA_IucC; pfam04183
1429244002732	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1429244002733	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
1429244002734	hypothetical protein; Provisional; Region: PRK13660
1429244002735	Rhamnogalacturonan lyase of the polysaccharide lyase family 11; Region: RGL11; cd10318
1429244002736	metal binding site [ion binding]; metal-binding site
1429244002737	active site
1429244002738	YvrJ protein family; Region: YvrJ; pfam12841
1429244002739	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1429244002740	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244002741	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1429244002742	active site
1429244002743	motif I; other site
1429244002744	motif II; other site
1429244002745	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1429244002746	WXG100 family type VII secretion target; Region: WXG100_ESAT6; TIGR03930
1429244002747	tellurite resistance protein terB; Region: terB; cd07176
1429244002748	putative metal binding site [ion binding]; other site
1429244002749	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1429244002750	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1429244002751	putative metal binding site [ion binding]; other site
1429244002752	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1429244002753	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1429244002754	putative metal binding site [ion binding]; other site
1429244002755	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1429244002756	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1429244002757	putative metal binding site [ion binding]; other site
1429244002758	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1429244002759	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1429244002760	putative metal binding site [ion binding]; other site
1429244002761	Uncharacterized protein involved in stress response [General function prediction only]; Region: COG4110
1429244002762	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1429244002763	putative metal binding site [ion binding]; other site
1429244002764	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1429244002765	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1429244002766	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244002767	active site
1429244002768	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
1429244002769	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
1429244002770	sucrose-phosphate phosphatase subfamily; Region: SPP-subfamily; TIGR01482
1429244002771	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1429244002772	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1429244002773	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
1429244002774	zinc binding site [ion binding]; other site
1429244002775	Domain of unknown function (DUF3899); Region: DUF3899; pfam13038
1429244002776	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1429244002777	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1429244002778	peptide binding site [polypeptide binding]; other site
1429244002779	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244002780	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002781	dimer interface [polypeptide binding]; other site
1429244002782	conserved gate region; other site
1429244002783	putative PBP binding loops; other site
1429244002784	ABC-ATPase subunit interface; other site
1429244002785	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244002786	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002787	dimer interface [polypeptide binding]; other site
1429244002788	conserved gate region; other site
1429244002789	putative PBP binding loops; other site
1429244002790	ABC-ATPase subunit interface; other site
1429244002791	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244002792	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244002793	substrate binding pocket [chemical binding]; other site
1429244002794	membrane-bound complex binding site; other site
1429244002795	hinge residues; other site
1429244002796	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002797	dimer interface [polypeptide binding]; other site
1429244002798	conserved gate region; other site
1429244002799	putative PBP binding loops; other site
1429244002800	ABC-ATPase subunit interface; other site
1429244002801	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244002802	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244002803	Walker A/P-loop; other site
1429244002804	ATP binding site [chemical binding]; other site
1429244002805	Q-loop/lid; other site
1429244002806	ABC transporter signature motif; other site
1429244002807	Walker B; other site
1429244002808	D-loop; other site
1429244002809	H-loop/switch region; other site
1429244002810	Protein of unknown function (DUF3159); Region: DUF3159; pfam11361
1429244002811	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244002812	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244002813	Protein of unknown function (DUF3782); Region: DUF3782; pfam12644
1429244002814	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244002815	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244002816	non-specific DNA binding site [nucleotide binding]; other site
1429244002817	salt bridge; other site
1429244002818	sequence-specific DNA binding site [nucleotide binding]; other site
1429244002819	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244002820	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244002821	non-specific DNA binding site [nucleotide binding]; other site
1429244002822	salt bridge; other site
1429244002823	sequence-specific DNA binding site [nucleotide binding]; other site
1429244002824	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
1429244002825	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244002826	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1429244002827	metal binding site [ion binding]; metal-binding site
1429244002828	dimer interface [polypeptide binding]; other site
1429244002829	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1429244002830	enoyl-CoA hydratase; Region: PLN02600
1429244002831	substrate binding site [chemical binding]; other site
1429244002832	oxyanion hole (OAH) forming residues; other site
1429244002833	trimer interface [polypeptide binding]; other site
1429244002834	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1429244002835	substrate binding site [chemical binding]; other site
1429244002836	trimer interface [polypeptide binding]; other site
1429244002837	oxyanion hole (OAH) forming residues; other site
1429244002838	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1429244002839	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1429244002840	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244002841	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244002842	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1429244002843	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1429244002844	tetracycline repressor protein TetR; Provisional; Region: PRK13756
1429244002845	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244002846	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1429244002847	maltose O-acetyltransferase; Provisional; Region: PRK10092
1429244002848	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1429244002849	active site
1429244002850	substrate binding site [chemical binding]; other site
1429244002851	trimer interface [polypeptide binding]; other site
1429244002852	CoA binding site [chemical binding]; other site
1429244002853	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244002854	DNA-binding site [nucleotide binding]; DNA binding site
1429244002855	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1429244002856	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244002857	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244002858	homodimer interface [polypeptide binding]; other site
1429244002859	catalytic residue [active]
1429244002860	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1429244002861	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244002862	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244002863	putative substrate translocation pore; other site
1429244002864	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1429244002865	active site
1429244002866	oligomerization interface [polypeptide binding]; other site
1429244002867	metal binding site [ion binding]; metal-binding site
1429244002868	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244002869	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1429244002870	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244002871	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244002872	active site
1429244002873	catalytic tetrad [active]
1429244002874	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244002875	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1429244002876	DNA binding residues [nucleotide binding]
1429244002877	putative dimer interface [polypeptide binding]; other site
1429244002878	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244002879	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1429244002880	putative active site [active]
1429244002881	putative FMN binding site [chemical binding]; other site
1429244002882	putative substrate binding site [chemical binding]; other site
1429244002883	putative catalytic residue [active]
1429244002884	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1429244002885	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244002886	NAD(P) binding site [chemical binding]; other site
1429244002887	active site
1429244002888	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1429244002889	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
1429244002890	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1429244002891	alpha-galactosidase; Provisional; Region: PRK15076
1429244002892	NAD binding site [chemical binding]; other site
1429244002893	sugar binding site [chemical binding]; other site
1429244002894	divalent metal binding site [ion binding]; other site
1429244002895	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244002896	dimer interface [polypeptide binding]; other site
1429244002897	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244002898	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1429244002899	Histidine kinase; Region: His_kinase; pfam06580
1429244002900	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244002901	ATP binding site [chemical binding]; other site
1429244002902	Mg2+ binding site [ion binding]; other site
1429244002903	G-X-G motif; other site
1429244002904	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244002905	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244002906	active site
1429244002907	phosphorylation site [posttranslational modification]
1429244002908	intermolecular recognition site; other site
1429244002909	dimerization interface [polypeptide binding]; other site
1429244002910	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1429244002911	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244002912	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244002913	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244002914	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244002915	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002916	dimer interface [polypeptide binding]; other site
1429244002917	conserved gate region; other site
1429244002918	putative PBP binding loops; other site
1429244002919	ABC-ATPase subunit interface; other site
1429244002920	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244002921	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244002922	dimer interface [polypeptide binding]; other site
1429244002923	conserved gate region; other site
1429244002924	putative PBP binding loops; other site
1429244002925	ABC-ATPase subunit interface; other site
1429244002926	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1429244002927	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1429244002928	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1429244002929	active site
1429244002930	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1429244002931	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1429244002932	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
1429244002933	Proline racemase; Region: Pro_racemase; pfam05544
1429244002934	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1429244002935	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1429244002936	inhibitor site; inhibition site
1429244002937	active site
1429244002938	dimer interface [polypeptide binding]; other site
1429244002939	catalytic residue [active]
1429244002940	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1429244002941	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1429244002942	NAD(P) binding site [chemical binding]; other site
1429244002943	catalytic residues [active]
1429244002944	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1429244002945	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510
1429244002946	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1429244002947	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1429244002948	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1429244002949	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1429244002950	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244002951	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244002952	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244002953	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244002954	dimerization interface [polypeptide binding]; other site
1429244002955	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244002956	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
1429244002957	metal binding site [ion binding]; metal-binding site
1429244002958	Predicted membrane protein [Function unknown]; Region: COG1288
1429244002959	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1429244002960	Rhamnogalacturonan lyase of the polysaccharide lyase family 11; Region: RGL11; cd10318
1429244002961	Rhamnogalacturonan lyase of the polysaccharide lyase family 11; Region: RGL11; cd10318
1429244002962	metal binding site [ion binding]; metal-binding site
1429244002963	active site
1429244002964	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244002965	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244002966	DNA binding site [nucleotide binding]
1429244002967	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1429244002968	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244002969	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
1429244002970	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
1429244002971	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
1429244002972	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244002973	active site
1429244002974	substrate binding [chemical binding]; other site
1429244002975	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244002976	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
1429244002977	nitrogenase cofactor biosynthesis protein NifB; Region: nifB; TIGR01290
1429244002978	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244002979	FeS/SAM binding site; other site
1429244002980	NifB belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme as part of...; Region: NifB; cd00852
1429244002981	nitrogenase reductase; Reviewed; Region: nifH; PRK13234
1429244002982	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
1429244002983	Nucleotide-binding sites [chemical binding]; other site
1429244002984	Walker A motif; other site
1429244002985	Switch I region of nucleotide binding site; other site
1429244002986	Fe4S4 binding sites [ion binding]; other site
1429244002987	Switch II region of nucleotide binding site; other site
1429244002988	Nitrogenase_MoFe_alpha_II: Nitrogenase MoFe protein, beta subunit. A group of proteins similar to the alpha subunit of the MoFe protein of the molybdenum (Mo-) nitrogenase. The nitrogenase enzyme catalyzes the ATP-dependent reduction of dinitrogen to...; Region: Nitrogenase_MoFe_alpha; cd01976
1429244002989	nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Region: nifE; TIGR01283
1429244002990	MoFe protein alpha/beta subunit interactions; other site
1429244002991	Alpha subunit P cluster binding residues; other site
1429244002992	FeMoco binding residues [chemical binding]; other site
1429244002993	MoFe protein alpha subunit/Fe protein contacts; other site
1429244002994	MoFe protein dimer/ dimer interactions; other site
1429244002995	nitrogenase molybdenum-iron protein beta chain; Region: nifK; TIGR01286
1429244002996	Domain of unknown function (DUF3364); Region: DUF3364; pfam11844
1429244002997	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1429244002998	nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Region: nifE; TIGR01283
1429244002999	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1429244003000	Nitrogenase_nifN1: A subgroup of the NifN subunit of the NifEN complex: NifN forms an alpha2beta2 tetramer with NifE.  NifN and nifE are structurally homologous to nitrogenase MoFe protein beta and alpha subunits respectively.  NifEN participates in the...; Region: Nitrogenase_NifN_1; cd01966
1429244003001	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1429244003002	NifX belongs to a family of iron-molybdenum cluster-binding proteins that includes NifB,  and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  The protein...; Region: NifX; cd00853
1429244003003	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
1429244003004	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1429244003005	ATP binding site [chemical binding]; other site
1429244003006	substrate interface [chemical binding]; other site
1429244003007	trans-homoaconitate synthase; Reviewed; Region: aksA; PRK11858
1429244003008	Streptomyces rubellomurinus FrbC and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_NifV; cd07939
1429244003009	active site
1429244003010	catalytic residues [active]
1429244003011	metal binding site [ion binding]; metal-binding site
1429244003012	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244003013	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244003014	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244003015	Walker A/P-loop; other site
1429244003016	ATP binding site [chemical binding]; other site
1429244003017	Q-loop/lid; other site
1429244003018	ABC transporter signature motif; other site
1429244003019	Walker B; other site
1429244003020	D-loop; other site
1429244003021	H-loop/switch region; other site
1429244003022	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244003023	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244003024	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1429244003025	Walker A/P-loop; other site
1429244003026	ATP binding site [chemical binding]; other site
1429244003027	Q-loop/lid; other site
1429244003028	ABC transporter signature motif; other site
1429244003029	Walker B; other site
1429244003030	D-loop; other site
1429244003031	H-loop/switch region; other site
1429244003032	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1429244003033	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
1429244003034	conserved cys residue [active]
1429244003035	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244003036	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244003037	putative substrate translocation pore; other site
1429244003038	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244003039	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244003040	Cupin domain; Region: Cupin_2; pfam07883
1429244003041	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244003042	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003043	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003044	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1429244003045	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244003046	putative substrate translocation pore; other site
1429244003047	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244003048	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244003049	active site
1429244003050	phosphorylation site [posttranslational modification]
1429244003051	intermolecular recognition site; other site
1429244003052	dimerization interface [polypeptide binding]; other site
1429244003053	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244003054	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003055	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003056	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244003057	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244003058	dimerization interface [polypeptide binding]; other site
1429244003059	Histidine kinase; Region: His_kinase; pfam06580
1429244003060	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244003061	ATP binding site [chemical binding]; other site
1429244003062	Mg2+ binding site [ion binding]; other site
1429244003063	G-X-G motif; other site
1429244003064	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1429244003065	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1429244003066	ligand binding site [chemical binding]; other site
1429244003067	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1429244003068	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244003069	active site
1429244003070	motif I; other site
1429244003071	motif II; other site
1429244003072	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244003073	alpha-galactosidase; Provisional; Region: PRK15076
1429244003074	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1429244003075	NAD binding site [chemical binding]; other site
1429244003076	sugar binding site [chemical binding]; other site
1429244003077	divalent metal binding site [ion binding]; other site
1429244003078	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244003079	dimer interface [polypeptide binding]; other site
1429244003080	Cellobiohydrolase A (1,4-beta-cellobiosidase A) [Carbohydrate transport and metabolism]; Region: CelA; COG5297
1429244003081	Glycosyl hydrolases family 6; Region: Glyco_hydro_6; pfam01341
1429244003082	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244003083	Interdomain contacts; other site
1429244003084	Cytokine receptor motif; other site
1429244003085	Cellulose binding domain; Region: CBM_3; pfam00942
1429244003086	NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These...; Region: nuc_hydro_CaPnhB; cd02650
1429244003087	active site
1429244003088	PAS domain S-box; Region: sensory_box; TIGR00229
1429244003089	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244003090	putative active site [active]
1429244003091	heme pocket [chemical binding]; other site
1429244003092	PAS domain S-box; Region: sensory_box; TIGR00229
1429244003093	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244003094	putative active site [active]
1429244003095	heme pocket [chemical binding]; other site
1429244003096	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244003097	PAS fold; Region: PAS_3; pfam08447
1429244003098	putative active site [active]
1429244003099	heme pocket [chemical binding]; other site
1429244003100	PAS domain S-box; Region: sensory_box; TIGR00229
1429244003101	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244003102	putative active site [active]
1429244003103	heme pocket [chemical binding]; other site
1429244003104	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1429244003105	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244003106	putative active site [active]
1429244003107	heme pocket [chemical binding]; other site
1429244003108	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244003109	dimer interface [polypeptide binding]; other site
1429244003110	phosphorylation site [posttranslational modification]
1429244003111	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244003112	ATP binding site [chemical binding]; other site
1429244003113	Mg2+ binding site [ion binding]; other site
1429244003114	G-X-G motif; other site
1429244003115	Predicted transcriptional regulators [Transcription]; Region: COG1725
1429244003116	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244003117	DNA-binding site [nucleotide binding]; DNA binding site
1429244003118	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244003119	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1429244003120	Walker A/P-loop; other site
1429244003121	ATP binding site [chemical binding]; other site
1429244003122	Q-loop/lid; other site
1429244003123	ABC transporter signature motif; other site
1429244003124	Walker B; other site
1429244003125	D-loop; other site
1429244003126	H-loop/switch region; other site
1429244003127	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
1429244003128	Methyltransferase domain; Region: Methyltransf_11; pfam08241
1429244003129	PBP superfamily domain; Region: PBP_like_2; cl17296
1429244003130	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
1429244003131	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244003132	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244003133	active site
1429244003134	catalytic tetrad [active]
1429244003135	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1429244003136	active site
1429244003137	SUMO-1 interface [polypeptide binding]; other site
1429244003138	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1429244003139	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1429244003140	hexamer interface [polypeptide binding]; other site
1429244003141	ligand binding site [chemical binding]; other site
1429244003142	putative active site [active]
1429244003143	NAD(P) binding site [chemical binding]; other site
1429244003144	DRTGG domain; Region: DRTGG; pfam07085
1429244003145	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1429244003146	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1429244003147	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244003148	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1429244003149	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1429244003150	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
1429244003151	active site
1429244003152	catalytic triad [active]
1429244003153	oxyanion hole [active]
1429244003154	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1429244003155	Domain of unknown function DUF21; Region: DUF21; pfam01595
1429244003156	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1429244003157	Transporter associated domain; Region: CorC_HlyC; smart01091
1429244003158	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1429244003159	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244003160	dimerization interface [polypeptide binding]; other site
1429244003161	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244003162	dimer interface [polypeptide binding]; other site
1429244003163	putative CheW interface [polypeptide binding]; other site
1429244003164	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; pfam09529
1429244003165	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1429244003166	classical (c) SDRs; Region: SDR_c; cd05233
1429244003167	NAD(P) binding site [chemical binding]; other site
1429244003168	active site
1429244003169	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
1429244003170	MgtC family; Region: MgtC; pfam02308
1429244003171	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1429244003172	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1429244003173	active site
1429244003174	Protein of unknown function (DUF3886); Region: DUF3886; pfam13025
1429244003175	drug efflux system protein MdtG; Provisional; Region: PRK09874
1429244003176	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244003177	putative substrate translocation pore; other site
1429244003178	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1429244003179	EamA-like transporter family; Region: EamA; pfam00892
1429244003180	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1429244003181	EamA-like transporter family; Region: EamA; pfam00892
1429244003182	Predicted transcriptional regulators [Transcription]; Region: COG1378
1429244003183	Sugar-specific transcriptional regulator TrmB; Region: TrmB; pfam01978
1429244003184	Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins; Region: PLDc_like_TrmB_middle; cd09124
1429244003185	C-terminal domain interface [polypeptide binding]; other site
1429244003186	sugar binding site [chemical binding]; other site
1429244003187	Protein of unknown function (DUF1593); Region: DUF1593; pfam07632
1429244003188	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed; Region: PRK12595
1429244003189	Chorismate mutase type II; Region: CM_2; cl00693
1429244003190	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1429244003191	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1429244003192	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
1429244003193	putative active site [active]
1429244003194	catalytic triad [active]
1429244003195	putative dimer interface [polypeptide binding]; other site
1429244003196	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244003197	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244003198	Coenzyme A binding pocket [chemical binding]; other site
1429244003199	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244003200	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244003201	dimer interface [polypeptide binding]; other site
1429244003202	phosphorylation site [posttranslational modification]
1429244003203	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244003204	ATP binding site [chemical binding]; other site
1429244003205	Mg2+ binding site [ion binding]; other site
1429244003206	G-X-G motif; other site
1429244003207	NHLP leader peptide domain; Region: TOMM_pelo; TIGR03793
1429244003208	Catalytic NodB homology domain of Streptomyces lividans acetylxylan esterase and its bacterial homologs; Region: CE4_SlAXE_like; cd10953
1429244003209	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1429244003210	NodB motif; other site
1429244003211	active site
1429244003212	catalytic site [active]
1429244003213	Zn binding site [ion binding]; other site
1429244003214	dimer interface [polypeptide binding]; other site
1429244003215	Carbohydrate Binding Module families 36 (CBM36) and 6 (CBM6); appended mainly to glycoside hydrolase family 11 (GH11) domains; xylan binding; Region: CBM6_36_xylanase-like; cd04078
1429244003216	Ca binding site [ion binding]; other site
1429244003217	Ca binding site (active) [ion binding]; other site
1429244003218	ligand binding site [chemical binding]; other site
1429244003219	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
1429244003220	Carbohydrate Binding Module families 36 (CBM36) and 6 (CBM6); appended mainly to glycoside hydrolase family 11 (GH11) domains; xylan binding; Region: CBM6_36_xylanase-like; cd04078
1429244003221	Ca binding site [ion binding]; other site
1429244003222	Ca binding site (active) [ion binding]; other site
1429244003223	ligand binding site [chemical binding]; other site
1429244003224	Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600
1429244003225	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244003226	MarR family; Region: MarR_2; pfam12802
1429244003227	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1429244003228	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1429244003229	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003230	non-specific DNA binding site [nucleotide binding]; other site
1429244003231	salt bridge; other site
1429244003232	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003233	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1429244003234	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244003235	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1429244003236	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1429244003237	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_2; cd06310
1429244003238	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1429244003239	putative ligand binding site [chemical binding]; other site
1429244003240	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244003241	Cache domain; Region: Cache_1; pfam02743
1429244003242	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244003243	dimerization interface [polypeptide binding]; other site
1429244003244	Histidine kinase; Region: His_kinase; pfam06580
1429244003245	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244003246	ATP binding site [chemical binding]; other site
1429244003247	Mg2+ binding site [ion binding]; other site
1429244003248	G-X-G motif; other site
1429244003249	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244003250	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244003251	active site
1429244003252	phosphorylation site [posttranslational modification]
1429244003253	intermolecular recognition site; other site
1429244003254	dimerization interface [polypeptide binding]; other site
1429244003255	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244003256	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003257	hydroxylamine reductase; Provisional; Region: PRK12310
1429244003258	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1429244003259	ACS interaction site; other site
1429244003260	CODH interaction site; other site
1429244003261	metal cluster binding site [ion binding]; other site
1429244003262	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003263	non-specific DNA binding site [nucleotide binding]; other site
1429244003264	salt bridge; other site
1429244003265	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003266	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1429244003267	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1429244003268	Part of AAA domain; Region: AAA_19; pfam13245
1429244003269	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
1429244003270	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1429244003271	putative ligand binding site [chemical binding]; other site
1429244003272	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1429244003273	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1429244003274	Walker A/P-loop; other site
1429244003275	ATP binding site [chemical binding]; other site
1429244003276	Q-loop/lid; other site
1429244003277	ABC transporter signature motif; other site
1429244003278	Walker B; other site
1429244003279	D-loop; other site
1429244003280	H-loop/switch region; other site
1429244003281	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1429244003282	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1429244003283	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1429244003284	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1429244003285	TM-ABC transporter signature motif; other site
1429244003286	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1429244003287	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1429244003288	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1429244003289	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244003290	putative DNA binding site [nucleotide binding]; other site
1429244003291	putative Zn2+ binding site [ion binding]; other site
1429244003292	AsnC family; Region: AsnC_trans_reg; pfam01037
1429244003293	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1429244003294	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244003295	EcsC protein family; Region: EcsC; pfam12787
1429244003296	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244003297	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244003298	putative substrate translocation pore; other site
1429244003299	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244003300	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1429244003301	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1429244003302	active site
1429244003303	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1429244003304	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244003305	active site turn [active]
1429244003306	phosphorylation site [posttranslational modification]
1429244003307	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244003308	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1429244003309	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1429244003310	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1429244003311	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1429244003312	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244003313	substrate binding [chemical binding]; other site
1429244003314	active site
1429244003315	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244003316	Cupin domain; Region: Cupin_2; pfam07883
1429244003317	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244003318	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003319	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003320	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
1429244003321	7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: Bsubt_queE; TIGR03365
1429244003322	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244003323	FeS/SAM binding site; other site
1429244003324	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1429244003325	active site
1429244003326	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1429244003327	Ligand Binding Site [chemical binding]; other site
1429244003328	Mitochondrial biogenesis AIM24; Region: AIM24; cl00884
1429244003329	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
1429244003330	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244003331	HTH domain; Region: HTH_11; pfam08279
1429244003332	WYL domain; Region: WYL; pfam13280
1429244003333	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
1429244003334	active site
1429244003335	catalytic site [active]
1429244003336	substrate binding site [chemical binding]; other site
1429244003337	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1429244003338	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1429244003339	active site
1429244003340	metal binding site [ion binding]; metal-binding site
1429244003341	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1429244003342	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244003343	Domain of unknown function (DUF955); Region: DUF955; pfam06114
1429244003344	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244003345	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003346	non-specific DNA binding site [nucleotide binding]; other site
1429244003347	salt bridge; other site
1429244003348	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003349	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
1429244003350	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
1429244003351	Protein of unknown function (DUF2001); Region: DUF2001; pfam09393
1429244003352	Phage XkdN-like protein; Region: XkdN; pfam08890
1429244003353	Uncharacterized protein containing LysM domain [Function unknown]; Region: XkdP; COG1652
1429244003354	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244003355	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
1429244003356	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1429244003357	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
1429244003358	Holin family; Region: Phage_holin_4; pfam05105
1429244003359	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cd00599
1429244003360	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1429244003361	active site
1429244003362	Condensation domain; Region: Condensation; pfam00668
1429244003363	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244003364	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244003365	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1429244003366	acyl-activating enzyme (AAE) consensus motif; other site
1429244003367	AMP binding site [chemical binding]; other site
1429244003368	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003369	Condensation domain; Region: Condensation; pfam00668
1429244003370	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003371	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1429244003372	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244003373	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244003374	ABC-type siderophore export system, fused ATPase and permease components [Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism]; Region: PvdE; COG4615
1429244003375	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244003376	Walker A/P-loop; other site
1429244003377	ATP binding site [chemical binding]; other site
1429244003378	ABC transporter signature motif; other site
1429244003379	Walker B; other site
1429244003380	D-loop; other site
1429244003381	H-loop/switch region; other site
1429244003382	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1429244003383	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1429244003384	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1429244003385	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1429244003386	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1429244003387	Condensation domain; Region: Condensation; pfam00668
1429244003388	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003389	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1244
1429244003390	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1429244003391	FeS/SAM binding site; other site
1429244003392	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244003393	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1429244003394	acyl-activating enzyme (AAE) consensus motif; other site
1429244003395	AMP binding site [chemical binding]; other site
1429244003396	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003397	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244003398	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1429244003399	active site
1429244003400	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244003401	S-adenosylmethionine binding site [chemical binding]; other site
1429244003402	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244003403	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1429244003404	active site
1429244003405	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1429244003406	putative NADP binding site [chemical binding]; other site
1429244003407	active site
1429244003408	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003409	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244003410	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1429244003411	active site
1429244003412	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003413	Condensation domain; Region: Condensation; pfam00668
1429244003414	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003415	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244003416	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1429244003417	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244003418	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244003419	homodimer interface [polypeptide binding]; other site
1429244003420	catalytic residue [active]
1429244003421	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244003422	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1429244003423	acyl-activating enzyme (AAE) consensus motif; other site
1429244003424	AMP binding site [chemical binding]; other site
1429244003425	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003426	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244003427	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1429244003428	active site
1429244003429	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1429244003430	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1429244003431	putative NADP binding site [chemical binding]; other site
1429244003432	active site
1429244003433	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003434	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1429244003435	Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192
1429244003436	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
1429244003437	Condensation domain; Region: Condensation; pfam00668
1429244003438	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003439	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244003440	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1429244003441	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244003442	acyl-activating enzyme (AAE) consensus motif; other site
1429244003443	AMP binding site [chemical binding]; other site
1429244003444	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003445	Condensation domain; Region: Condensation; pfam00668
1429244003446	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003447	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244003448	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244003449	acyl-activating enzyme (AAE) consensus motif; other site
1429244003450	AMP binding site [chemical binding]; other site
1429244003451	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003452	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1429244003453	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1429244003454	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1429244003455	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244003456	active site
1429244003457	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1429244003458	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1429244003459	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1429244003460	putative NADP binding site [chemical binding]; other site
1429244003461	active site
1429244003462	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003463	Condensation domain; Region: Condensation; pfam00668
1429244003464	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003465	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244003466	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1429244003467	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244003468	acyl-activating enzyme (AAE) consensus motif; other site
1429244003469	AMP binding site [chemical binding]; other site
1429244003470	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003471	Condensation domain; Region: Condensation; pfam00668
1429244003472	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003473	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244003474	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244003475	acyl-activating enzyme (AAE) consensus motif; other site
1429244003476	AMP binding site [chemical binding]; other site
1429244003477	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003478	Condensation domain; Region: Condensation; pfam00668
1429244003479	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244003480	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244003481	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1429244003482	acyl-activating enzyme (AAE) consensus motif; other site
1429244003483	AMP binding site [chemical binding]; other site
1429244003484	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244003485	Thioesterase domain; Region: Thioesterase; pfam00975
1429244003486	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244003487	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1429244003488	peptide binding site [polypeptide binding]; other site
1429244003489	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244003490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244003491	dimer interface [polypeptide binding]; other site
1429244003492	conserved gate region; other site
1429244003493	putative PBP binding loops; other site
1429244003494	ABC-ATPase subunit interface; other site
1429244003495	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244003496	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244003497	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244003498	dimer interface [polypeptide binding]; other site
1429244003499	conserved gate region; other site
1429244003500	putative PBP binding loops; other site
1429244003501	ABC-ATPase subunit interface; other site
1429244003502	dGTP triphosphohydrolase [Nucleotide transport and metabolism]; Region: Dgt; COG0232
1429244003503	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244003504	Zn2+ binding site [ion binding]; other site
1429244003505	Mg2+ binding site [ion binding]; other site
1429244003506	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1429244003507	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1429244003508	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1429244003509	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1429244003510	THUMP domain, predicted to bind RNA; Region: THUMP; cl12076
1429244003511	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244003512	S-adenosylmethionine binding site [chemical binding]; other site
1429244003513	Putative D-isomer specific 2-hydroxyacid dehydrogenase; Region: 2-Hacid_dh_1; cd05300
1429244003514	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1429244003515	NAD binding site [chemical binding]; other site
1429244003516	ligand binding site [chemical binding]; other site
1429244003517	catalytic site [active]
1429244003518	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
1429244003519	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1429244003520	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1429244003521	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1429244003522	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1429244003523	metal-dependent hydrolase; Provisional; Region: PRK00685
1429244003524	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244003525	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244003526	DNA binding residues [nucleotide binding]
1429244003527	dimerization interface [polypeptide binding]; other site
1429244003528	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
1429244003529	Chain length determinant protein; Region: Wzz; cl15801
1429244003530	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1429244003531	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1429244003532	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1429244003533	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1429244003534	active site
1429244003535	tetramer interface; other site
1429244003536	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1429244003537	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1429244003538	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244003539	active site
1429244003540	O-Antigen ligase; Region: Wzy_C; pfam04932
1429244003541	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1429244003542	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1429244003543	O-Antigen ligase; Region: Wzy_C; pfam04932
1429244003544	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1429244003545	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1429244003546	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244003547	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1429244003548	putative metal binding site; other site
1429244003549	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244003550	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244003551	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244003552	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244003553	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244003554	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
1429244003555	putative ADP-binding pocket [chemical binding]; other site
1429244003556	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1429244003557	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1429244003558	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1429244003559	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1429244003560	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244003561	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1429244003562	active site
1429244003563	Cupin domain; Region: Cupin_2; cl17218
1429244003564	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
1429244003565	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
1429244003566	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1429244003567	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003568	non-specific DNA binding site [nucleotide binding]; other site
1429244003569	salt bridge; other site
1429244003570	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003571	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
1429244003572	Chain length determinant protein; Region: Wzz; cl15801
1429244003573	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1429244003574	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1429244003575	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1429244003576	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1429244003577	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1429244003578	NADP binding site [chemical binding]; other site
1429244003579	active site
1429244003580	putative substrate binding site [chemical binding]; other site
1429244003581	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1429244003582	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1429244003583	NADP-binding site; other site
1429244003584	homotetramer interface [polypeptide binding]; other site
1429244003585	substrate binding site [chemical binding]; other site
1429244003586	homodimer interface [polypeptide binding]; other site
1429244003587	active site
1429244003588	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1429244003589	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1429244003590	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244003591	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244003592	This family is most closely related to the GT1 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II); Region: GT1_ExpE7_like; cd03823
1429244003593	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244003594	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1429244003595	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1429244003596	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1429244003597	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1429244003598	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1429244003599	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1429244003600	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1429244003601	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244003602	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244003603	Walker A/P-loop; other site
1429244003604	ATP binding site [chemical binding]; other site
1429244003605	Q-loop/lid; other site
1429244003606	ABC transporter signature motif; other site
1429244003607	Walker B; other site
1429244003608	D-loop; other site
1429244003609	H-loop/switch region; other site
1429244003610	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1429244003611	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244003612	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1429244003613	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1429244003614	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1429244003615	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1429244003616	TATA element modulatory factor 1 TATA binding; Region: TMF_TATA_bd; pfam12325
1429244003617	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1429244003618	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244003619	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1429244003620	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1429244003621	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1429244003622	putative active site [active]
1429244003623	catalytic site [active]
1429244003624	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1429244003625	putative active site [active]
1429244003626	catalytic site [active]
1429244003627	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1429244003628	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244003629	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244003630	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1429244003631	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
1429244003632	nucleotide binding site [chemical binding]; other site
1429244003633	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
1429244003634	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1429244003635	active site
1429244003636	dimer interface [polypeptide binding]; other site
1429244003637	Glutamine amidotransferase domain; Region: GATase_6; pfam13522
1429244003638	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1429244003639	Ligand Binding Site [chemical binding]; other site
1429244003640	Molecular Tunnel; other site
1429244003641	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
1429244003642	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
1429244003643	active site
1429244003644	metal-binding site [ion binding]
1429244003645	active site
1429244003646	nucleotide-binding site [chemical binding]; other site
1429244003647	nucleotide-binding site [chemical binding]; other site
1429244003648	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
1429244003649	Transglutaminase-like superfamily; Region: Transglut_core3; pfam13471
1429244003650	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244003651	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244003652	Walker A/P-loop; other site
1429244003653	ATP binding site [chemical binding]; other site
1429244003654	Q-loop/lid; other site
1429244003655	ABC transporter signature motif; other site
1429244003656	Walker B; other site
1429244003657	D-loop; other site
1429244003658	H-loop/switch region; other site
1429244003659	Ku protein, prokaryotic; Region: Ku_bact; TIGR02772
1429244003660	Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku...; Region: KU_like; cd00789
1429244003661	putative DNA binding site [nucleotide binding]; other site
1429244003662	putative homodimer interface [polypeptide binding]; other site
1429244003663	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1429244003664	homotrimer interaction site [polypeptide binding]; other site
1429244003665	putative active site [active]
1429244003666	Small acid-soluble spore protein H family; Region: SspH; cl06949
1429244003667	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1429244003668	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1429244003669	acetoacetate decarboxylase; Provisional; Region: PRK02265
1429244003670	putative acyltransferase; Provisional; Region: PRK05790
1429244003671	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1429244003672	dimer interface [polypeptide binding]; other site
1429244003673	active site
1429244003674	Isochorismatase family; Region: Isochorismatase; pfam00857
1429244003675	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
1429244003676	catalytic triad [active]
1429244003677	conserved cis-peptide bond; other site
1429244003678	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1429244003679	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1429244003680	Glycoprotease family; Region: Peptidase_M22; pfam00814
1429244003681	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1429244003682	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244003683	Coenzyme A binding pocket [chemical binding]; other site
1429244003684	UGMP family protein; Validated; Region: PRK09604
1429244003685	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1429244003686	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1429244003687	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1429244003688	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244003689	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244003690	ABC transporter; Region: ABC_tran_2; pfam12848
1429244003691	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244003692	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1429244003693	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1429244003694	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1429244003695	trimer interface [polypeptide binding]; other site
1429244003696	dimer interface [polypeptide binding]; other site
1429244003697	putative active site [active]
1429244003698	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1429244003699	MPT binding site; other site
1429244003700	trimer interface [polypeptide binding]; other site
1429244003701	twin arginine translocase protein A; Provisional; Region: tatA; PRK14861
1429244003702	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1429244003703	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1429244003704	oligomerisation interface [polypeptide binding]; other site
1429244003705	mobile loop; other site
1429244003706	roof hairpin; other site
1429244003707	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1429244003708	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1429244003709	ring oligomerisation interface [polypeptide binding]; other site
1429244003710	ATP/Mg binding site [chemical binding]; other site
1429244003711	stacking interactions; other site
1429244003712	hinge regions; other site
1429244003713	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
1429244003714	Int/Topo IB signature motif; other site
1429244003715	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244003716	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003717	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003718	salt bridge; other site
1429244003719	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1429244003720	Catalytic site [active]
1429244003721	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244003722	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003723	non-specific DNA binding site [nucleotide binding]; other site
1429244003724	salt bridge; other site
1429244003725	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003726	Helix-turn-helix domain; Region: HTH_17; pfam12728
1429244003727	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
1429244003728	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1429244003729	HNH endonuclease; Region: HNH_3; pfam13392
1429244003730	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1429244003731	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1429244003732	dimer interface [polypeptide binding]; other site
1429244003733	ssDNA binding site [nucleotide binding]; other site
1429244003734	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244003735	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
1429244003736	hypothetical protein; Provisional; Region: PRK06921
1429244003737	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244003738	Walker A motif; other site
1429244003739	ATP binding site [chemical binding]; other site
1429244003740	Walker B motif; other site
1429244003741	arginine finger; other site
1429244003742	Protein of unknown function (DUF1064); Region: DUF1064; pfam06356
1429244003743	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1429244003744	DNA methylase; Region: N6_N4_Mtase; pfam01555
1429244003745	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1429244003746	KTSC domain; Region: KTSC; pfam13619
1429244003747	Uncharacterized conserved protein [Function unknown]; Region: COG5484
1429244003748	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1429244003749	Phage terminase large subunit; Region: Terminase_3; cl12054
1429244003750	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
1429244003751	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
1429244003752	NAD+--asparagine ADP-ribosyltransferase [Signal transduction mechanisms]; Region: COG5585
1429244003753	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1429244003754	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
1429244003755	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1429244003756	Head-Tail Connector Protein gp15 of Bacteriophage SPP1 and similar proteins; Region: gp15; cd08055
1429244003757	Bacteriophage protein of unknown function (DUF646); Region: DUF646; cl12124
1429244003758	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
1429244003759	Protein of unknown function (DUF2001); Region: DUF2001; pfam09393
1429244003760	Phage XkdN-like protein; Region: XkdN; pfam08890
1429244003761	Phage-related protein [Function unknown]; Region: COG5412
1429244003762	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244003763	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244003764	Protein of unknown function (DUF2577); Region: DUF2577; pfam10844
1429244003765	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
1429244003766	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1429244003767	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
1429244003768	Holin family; Region: Phage_holin_4; pfam05105
1429244003769	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1429244003770	amidase catalytic site [active]
1429244003771	Zn binding residues [ion binding]; other site
1429244003772	substrate binding site [chemical binding]; other site
1429244003773	Phage holin protein (Holin_LLH); Region: Holin_LLH; cl09890
1429244003774	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1429244003775	active site
1429244003776	catalytic residues [active]
1429244003777	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1429244003778	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244003779	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1429244003780	DNA binding residues [nucleotide binding]
1429244003781	putative dimer interface [polypeptide binding]; other site
1429244003782	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244003783	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244003784	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244003785	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003786	Predicted peptidase [General function prediction only]; Region: COG4099
1429244003787	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244003788	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
1429244003789	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1429244003790	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244003791	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244003792	dimer interface [polypeptide binding]; other site
1429244003793	putative PBP binding loops; other site
1429244003794	ABC-ATPase subunit interface; other site
1429244003795	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244003796	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244003797	dimer interface [polypeptide binding]; other site
1429244003798	conserved gate region; other site
1429244003799	putative PBP binding loops; other site
1429244003800	ABC-ATPase subunit interface; other site
1429244003801	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244003802	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1429244003803	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244003804	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244003805	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244003806	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244003807	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1429244003808	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1429244003809	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1429244003810	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1429244003811	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244003812	dimer interface [polypeptide binding]; other site
1429244003813	conserved gate region; other site
1429244003814	putative PBP binding loops; other site
1429244003815	ABC-ATPase subunit interface; other site
1429244003816	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1429244003817	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1429244003818	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
1429244003819	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1429244003820	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1429244003821	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1429244003822	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
1429244003823	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1429244003824	Walker A/P-loop; other site
1429244003825	ATP binding site [chemical binding]; other site
1429244003826	Q-loop/lid; other site
1429244003827	ABC transporter signature motif; other site
1429244003828	Walker B; other site
1429244003829	D-loop; other site
1429244003830	H-loop/switch region; other site
1429244003831	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1429244003832	Predicted transcriptional regulators [Transcription]; Region: COG1510
1429244003833	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1429244003834	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1429244003835	substrate binding pocket [chemical binding]; other site
1429244003836	catalytic triad [active]
1429244003837	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244003838	dimerization interface [polypeptide binding]; other site
1429244003839	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244003840	dimer interface [polypeptide binding]; other site
1429244003841	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1429244003842	putative CheW interface [polypeptide binding]; other site
1429244003843	EamA-like transporter family; Region: EamA; pfam00892
1429244003844	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244003845	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
1429244003846	Walker A/P-loop; other site
1429244003847	ATP binding site [chemical binding]; other site
1429244003848	Q-loop/lid; other site
1429244003849	ABC transporter signature motif; other site
1429244003850	Walker B; other site
1429244003851	D-loop; other site
1429244003852	H-loop/switch region; other site
1429244003853	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244003854	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244003855	dimer interface [polypeptide binding]; other site
1429244003856	phosphorylation site [posttranslational modification]
1429244003857	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244003858	ATP binding site [chemical binding]; other site
1429244003859	Mg2+ binding site [ion binding]; other site
1429244003860	G-X-G motif; other site
1429244003861	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244003862	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244003863	active site
1429244003864	phosphorylation site [posttranslational modification]
1429244003865	intermolecular recognition site; other site
1429244003866	dimerization interface [polypeptide binding]; other site
1429244003867	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244003868	DNA binding site [nucleotide binding]
1429244003869	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1429244003870	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1429244003871	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1429244003872	Potassium binding sites [ion binding]; other site
1429244003873	Cesium cation binding sites [ion binding]; other site
1429244003874	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003875	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244003876	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244003877	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244003878	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244003879	intersubunit interface [polypeptide binding]; other site
1429244003880	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244003881	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244003882	intersubunit interface [polypeptide binding]; other site
1429244003883	LysE type translocator; Region: LysE; cl00565
1429244003884	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
1429244003885	alanine racemase; Reviewed; Region: alr; PRK00053
1429244003886	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1429244003887	active site
1429244003888	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1429244003889	dimer interface [polypeptide binding]; other site
1429244003890	substrate binding site [chemical binding]; other site
1429244003891	catalytic residues [active]
1429244003892	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1429244003893	PemK-like protein; Region: PemK; pfam02452
1429244003894	hypothetical protein; Provisional; Region: PRK04351
1429244003895	SprT homologues; Region: SprT; cl01182
1429244003896	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244003897	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1429244003898	active site
1429244003899	motif I; other site
1429244003900	motif II; other site
1429244003901	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244003902	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1429244003903	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1429244003904	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1429244003905	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244003906	dimerization interface [polypeptide binding]; other site
1429244003907	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244003908	putative DNA binding site [nucleotide binding]; other site
1429244003909	putative Zn2+ binding site [ion binding]; other site
1429244003910	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244003911	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003912	non-specific DNA binding site [nucleotide binding]; other site
1429244003913	salt bridge; other site
1429244003914	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003915	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244003916	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244003917	non-specific DNA binding site [nucleotide binding]; other site
1429244003918	salt bridge; other site
1429244003919	sequence-specific DNA binding site [nucleotide binding]; other site
1429244003920	Predicted transcriptional regulator with an HTH domain [Transcription]; Region: COG4800
1429244003921	UreF; Region: UreF; pfam01730
1429244003922	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1429244003923	catalytic residues [active]
1429244003924	dimer interface [polypeptide binding]; other site
1429244003925	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1429244003926	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1429244003927	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1429244003928	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1429244003929	K+-transporting ATPase, c chain [Inorganic ion transport and metabolism]; Region: KdpC; COG2156
1429244003930	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244003931	Coenzyme A binding pocket [chemical binding]; other site
1429244003932	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1429244003933	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244003934	Coenzyme A binding pocket [chemical binding]; other site
1429244003935	manganese transport protein MntH; Reviewed; Region: PRK00701
1429244003936	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1429244003937	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1429244003938	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
1429244003939	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1429244003940	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244003941	intersubunit interface [polypeptide binding]; other site
1429244003942	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1429244003943	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1429244003944	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1429244003945	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244003946	dimer interface [polypeptide binding]; other site
1429244003947	ABC-ATPase subunit  interface; other site
1429244003948	putative PBP binding regions; other site
1429244003949	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1429244003950	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244003951	ABC-ATPase subunit  interface; other site
1429244003952	dimer interface [polypeptide binding]; other site
1429244003953	putative PBP binding regions; other site
1429244003954	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1429244003955	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1429244003956	Ligand Binding Site [chemical binding]; other site
1429244003957	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1429244003958	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1429244003959	Ligand Binding Site [chemical binding]; other site
1429244003960	AAA domain; Region: AAA_31; pfam13614
1429244003961	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
1429244003962	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1429244003963	ATP binding site [chemical binding]; other site
1429244003964	Walker A motif; other site
1429244003965	hexamer interface [polypeptide binding]; other site
1429244003966	Walker B motif; other site
1429244003967	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
1429244003968	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1429244003969	Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400
1429244003970	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1429244003971	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1429244003972	phosphopeptide binding site; other site
1429244003973	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1429244003974	TIGR01777 family protein; Region: yfcH
1429244003975	putative NAD(P) binding site [chemical binding]; other site
1429244003976	putative active site [active]
1429244003977	endonuclease IV; Provisional; Region: PRK01060
1429244003978	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1429244003979	AP (apurinic/apyrimidinic) site pocket; other site
1429244003980	DNA interaction; other site
1429244003981	Metal-binding active site; metal-binding site
1429244003982	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1429244003983	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1429244003984	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1429244003985	putative active site [active]
1429244003986	putative substrate binding site [chemical binding]; other site
1429244003987	putative cosubstrate binding site; other site
1429244003988	catalytic site [active]
1429244003989	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1429244003990	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1429244003991	TPP-binding site [chemical binding]; other site
1429244003992	dimer interface [polypeptide binding]; other site
1429244003993	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1429244003994	PYR/PP interface [polypeptide binding]; other site
1429244003995	dimer interface [polypeptide binding]; other site
1429244003996	TPP binding site [chemical binding]; other site
1429244003997	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1429244003998	Protein of unknown function (DUF1255); Region: DUF1255; pfam06865
1429244003999	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1429244004000	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1429244004001	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1429244004002	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1429244004003	active site
1429244004004	dimer interface [polypeptide binding]; other site
1429244004005	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1429244004006	dimer interface [polypeptide binding]; other site
1429244004007	active site
1429244004008	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1429244004009	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1429244004010	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1429244004011	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244004012	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244004013	WHG domain; Region: WHG; pfam13305
1429244004014	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
1429244004015	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1429244004016	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1429244004017	Walker A/P-loop; other site
1429244004018	ATP binding site [chemical binding]; other site
1429244004019	Q-loop/lid; other site
1429244004020	ABC transporter signature motif; other site
1429244004021	Walker B; other site
1429244004022	D-loop; other site
1429244004023	H-loop/switch region; other site
1429244004024	TOBE domain; Region: TOBE_2; pfam08402
1429244004025	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1429244004026	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1429244004027	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244004028	DNA-binding site [nucleotide binding]; DNA binding site
1429244004029	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244004030	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244004031	homodimer interface [polypeptide binding]; other site
1429244004032	catalytic residue [active]
1429244004033	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1429244004034	EamA-like transporter family; Region: EamA; pfam00892
1429244004035	EamA-like transporter family; Region: EamA; pfam00892
1429244004036	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244004037	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1429244004038	active site
1429244004039	motif I; other site
1429244004040	motif II; other site
1429244004041	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244004042	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1429244004043	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
1429244004044	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1429244004045	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
1429244004046	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244004047	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244004048	homodimer interface [polypeptide binding]; other site
1429244004049	catalytic residue [active]
1429244004050	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
1429244004051	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1429244004052	catalytic core [active]
1429244004053	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244004054	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1429244004055	cobalamin binding residues [chemical binding]; other site
1429244004056	putative BtuC binding residues; other site
1429244004057	dimer interface [polypeptide binding]; other site
1429244004058	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244004059	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244004060	ABC-ATPase subunit  interface; other site
1429244004061	dimer interface [polypeptide binding]; other site
1429244004062	putative PBP binding regions; other site
1429244004063	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244004064	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244004065	Walker A/P-loop; other site
1429244004066	ATP binding site [chemical binding]; other site
1429244004067	Q-loop/lid; other site
1429244004068	ABC transporter signature motif; other site
1429244004069	Walker B; other site
1429244004070	D-loop; other site
1429244004071	H-loop/switch region; other site
1429244004072	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1429244004073	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1429244004074	putative dimer interface [polypeptide binding]; other site
1429244004075	active site pocket [active]
1429244004076	putative cataytic base [active]
1429244004077	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1429244004078	homotrimer interface [polypeptide binding]; other site
1429244004079	Walker A motif; other site
1429244004080	GTP binding site [chemical binding]; other site
1429244004081	Walker B motif; other site
1429244004082	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1429244004083	cobyric acid synthase; Provisional; Region: PRK00784
1429244004084	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1429244004085	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1429244004086	catalytic triad [active]
1429244004087	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244004088	dimerization interface [polypeptide binding]; other site
1429244004089	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244004090	dimer interface [polypeptide binding]; other site
1429244004091	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244004092	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244004093	dimer interface [polypeptide binding]; other site
1429244004094	putative CheW interface [polypeptide binding]; other site
1429244004095	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244004096	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1429244004097	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244004098	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244004099	PRD domain; Region: PRD; pfam00874
1429244004100	PRD domain; Region: PRD; pfam00874
1429244004101	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244004102	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244004103	active site turn [active]
1429244004104	phosphorylation site [posttranslational modification]
1429244004105	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244004106	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244004107	HPr interaction site; other site
1429244004108	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244004109	active site
1429244004110	phosphorylation site [posttranslational modification]
1429244004111	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1429244004112	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1429244004113	Uncharacterized member of the PurR regulon [General function prediction only]; Region: yhhQ; COG1738
1429244004114	S-layer homology domain; Region: SLH; pfam00395
1429244004115	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1429244004116	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244004117	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1429244004118	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1429244004119	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1429244004120	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1429244004121	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244004122	rod shape-determining protein MreC; Provisional; Region: PRK13922
1429244004123	stage II sporulation protein E; Region: spore_II_E; TIGR02865
1429244004124	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244004125	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980
1429244004126	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1429244004127	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1429244004128	DNA binding residues [nucleotide binding]
1429244004129	Glutaredoxin-like domain (DUF836); Region: DUF836; cl17650
1429244004130	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1429244004131	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1429244004132	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1429244004133	active site
1429244004134	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244004135	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1429244004136	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244004137	Coenzyme A binding pocket [chemical binding]; other site
1429244004138	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
1429244004139	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1429244004140	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1429244004141	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1429244004142	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244004143	motif II; other site
1429244004144	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1429244004145	active site
1429244004146	ATP binding site [chemical binding]; other site
1429244004147	substrate binding site [chemical binding]; other site
1429244004148	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1429244004149	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
1429244004150	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1429244004151	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1429244004152	putative NAD(P) binding site [chemical binding]; other site
1429244004153	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1429244004154	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1429244004155	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1429244004156	active site
1429244004157	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
1429244004158	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244004159	ATP binding site [chemical binding]; other site
1429244004160	putative Mg++ binding site [ion binding]; other site
1429244004161	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244004162	nucleotide binding region [chemical binding]; other site
1429244004163	ATP-binding site [chemical binding]; other site
1429244004164	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1429244004165	HRDC domain; Region: HRDC; pfam00570
1429244004166	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
1429244004167	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1429244004168	Protein of unknown function (DUF4080); Region: DUF4080; pfam13311
1429244004169	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1429244004170	Alkaline phosphatase homologues; Region: alkPPc; smart00098
1429244004171	active site
1429244004172	dimer interface [polypeptide binding]; other site
1429244004173	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1429244004174	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1429244004175	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244004176	S-adenosylmethionine binding site [chemical binding]; other site
1429244004177	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244004178	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244004179	PRD domain; Region: PRD; pfam00874
1429244004180	PRD domain; Region: PRD; pfam00874
1429244004181	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244004182	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244004183	active site turn [active]
1429244004184	phosphorylation site [posttranslational modification]
1429244004185	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244004186	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244004187	HPr interaction site; other site
1429244004188	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244004189	active site
1429244004190	phosphorylation site [posttranslational modification]
1429244004191	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1429244004192	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244004193	Coenzyme A binding pocket [chemical binding]; other site
1429244004194	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
1429244004195	putative active site [active]
1429244004196	nucleotide binding site [chemical binding]; other site
1429244004197	nudix motif; other site
1429244004198	putative metal binding site [ion binding]; other site
1429244004199	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1429244004200	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244004201	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1429244004202	active site
1429244004203	ATP binding site [chemical binding]; other site
1429244004204	Predicted acetyltransferase [General function prediction only]; Region: COG3981
1429244004205	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244004206	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1429244004207	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1429244004208	HEAT repeats; Region: HEAT_2; pfam13646
1429244004209	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1429244004210	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244004211	Zn2+ binding site [ion binding]; other site
1429244004212	Mg2+ binding site [ion binding]; other site
1429244004213	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1429244004214	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
1429244004215	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244004216	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244004217	DNA binding residues [nucleotide binding]
1429244004218	dimerization interface [polypeptide binding]; other site
1429244004219	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244004220	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244004221	S-adenosylmethionine binding site [chemical binding]; other site
1429244004222	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
1429244004223	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244004224	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1429244004225	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244004226	motif II; other site
1429244004227	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244004228	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244004229	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
1429244004230	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1429244004231	active site
1429244004232	catalytic triad [active]
1429244004233	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1429244004234	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244004235	S-adenosylmethionine binding site [chemical binding]; other site
1429244004236	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244004237	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244004238	GIY-YIG domain of LuxR and ArsR family transcriptional regulators, and uncharacterized hypothetical proteins found in bacteria; Region: GIY-YIG_LuxR_like; cd10451
1429244004239	GIY-YIG motif/motif A; other site
1429244004240	Uncharacterized protein conserved in bacteria (DUF2087); Region: DUF2087; pfam09860
1429244004241	HEAT repeats; Region: HEAT_2; pfam13646
1429244004242	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1429244004243	non-specific DNA binding site [nucleotide binding]; other site
1429244004244	salt bridge; other site
1429244004245	sequence-specific DNA binding site [nucleotide binding]; other site
1429244004246	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244004247	non-specific DNA binding site [nucleotide binding]; other site
1429244004248	salt bridge; other site
1429244004249	sequence-specific DNA binding site [nucleotide binding]; other site
1429244004250	H+ Antiporter protein; Region: 2A0121; TIGR00900
1429244004251	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244004252	putative substrate translocation pore; other site
1429244004253	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1429244004254	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1429244004255	TPP-binding site [chemical binding]; other site
1429244004256	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1429244004257	dimer interface [polypeptide binding]; other site
1429244004258	PYR/PP interface [polypeptide binding]; other site
1429244004259	TPP binding site [chemical binding]; other site
1429244004260	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1429244004261	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1429244004262	E3 interaction surface; other site
1429244004263	lipoyl attachment site [posttranslational modification]; other site
1429244004264	e3 binding domain; Region: E3_binding; pfam02817
1429244004265	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1429244004266	metal-dependent hydrolase; Provisional; Region: PRK13291
1429244004267	DinB superfamily; Region: DinB_2; pfam12867
1429244004268	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1429244004269	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1429244004270	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1429244004271	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1429244004272	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244004273	S-adenosylmethionine binding site [chemical binding]; other site
1429244004274	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1429244004275	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244004276	S-adenosylmethionine binding site [chemical binding]; other site
1429244004277	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
1429244004278	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
1429244004279	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
1429244004280	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1429244004281	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1429244004282	active site
1429244004283	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1429244004284	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
1429244004285	DXD motif; other site
1429244004286	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1429244004287	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1429244004288	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1429244004289	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1429244004290	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1429244004291	23S rRNA binding site [nucleotide binding]; other site
1429244004292	L21 binding site [polypeptide binding]; other site
1429244004293	L13 binding site [polypeptide binding]; other site
1429244004294	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1429244004295	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1429244004296	ligand binding site [chemical binding]; other site
1429244004297	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
1429244004298	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244004299	Walker A/P-loop; other site
1429244004300	ATP binding site [chemical binding]; other site
1429244004301	Q-loop/lid; other site
1429244004302	ABC transporter signature motif; other site
1429244004303	Walker B; other site
1429244004304	D-loop; other site
1429244004305	H-loop/switch region; other site
1429244004306	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1429244004307	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1429244004308	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1429244004309	TM-ABC transporter signature motif; other site
1429244004310	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1429244004311	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1429244004312	TM-ABC transporter signature motif; other site
1429244004313	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1429244004314	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244004315	Coenzyme A binding pocket [chemical binding]; other site
1429244004316	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
1429244004317	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1429244004318	PYR/PP interface [polypeptide binding]; other site
1429244004319	dimer interface [polypeptide binding]; other site
1429244004320	TPP binding site [chemical binding]; other site
1429244004321	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1429244004322	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1429244004323	TPP-binding site [chemical binding]; other site
1429244004324	dimer interface [polypeptide binding]; other site
1429244004325	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1429244004326	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1429244004327	putative valine binding site [chemical binding]; other site
1429244004328	dimer interface [polypeptide binding]; other site
1429244004329	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1429244004330	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1429244004331	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1429244004332	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1429244004333	2-isopropylmalate synthase; Validated; Region: PRK00915
1429244004334	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1429244004335	active site
1429244004336	catalytic residues [active]
1429244004337	metal binding site [ion binding]; metal-binding site
1429244004338	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1429244004339	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1429244004340	tartrate dehydrogenase; Region: TTC; TIGR02089
1429244004341	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1429244004342	dimer interface [polypeptide binding]; other site
1429244004343	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1429244004344	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1429244004345	catalytic triad [active]
1429244004346	peroxidatic and resolving cysteines [active]
1429244004347	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244004348	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244004349	putative active site [active]
1429244004350	heme pocket [chemical binding]; other site
1429244004351	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244004352	dimer interface [polypeptide binding]; other site
1429244004353	phosphorylation site [posttranslational modification]
1429244004354	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244004355	ATP binding site [chemical binding]; other site
1429244004356	Mg2+ binding site [ion binding]; other site
1429244004357	G-X-G motif; other site
1429244004358	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244004359	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244004360	metal binding site [ion binding]; metal-binding site
1429244004361	active site
1429244004362	I-site; other site
1429244004363	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1429244004364	Pectate lyase [Carbohydrate transport and metabolism]; Region: PelB; COG3866
1429244004365	Pectate lyase; Region: Pec_lyase_C; cl01593
1429244004366	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1429244004367	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244004368	Walker A/P-loop; other site
1429244004369	ATP binding site [chemical binding]; other site
1429244004370	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244004371	ABC transporter signature motif; other site
1429244004372	Walker B; other site
1429244004373	D-loop; other site
1429244004374	ABC transporter; Region: ABC_tran_2; pfam12848
1429244004375	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244004376	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1429244004377	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1429244004378	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1429244004379	dimer interface [polypeptide binding]; other site
1429244004380	motif 1; other site
1429244004381	active site
1429244004382	motif 2; other site
1429244004383	motif 3; other site
1429244004384	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1429244004385	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1429244004386	putative tRNA-binding site [nucleotide binding]; other site
1429244004387	B3/4 domain; Region: B3_4; pfam03483
1429244004388	tRNA synthetase B5 domain; Region: B5; smart00874
1429244004389	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1429244004390	dimer interface [polypeptide binding]; other site
1429244004391	motif 1; other site
1429244004392	motif 3; other site
1429244004393	motif 2; other site
1429244004394	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
1429244004395	Cell division protein ZapA; Region: ZapA; cl01146
1429244004396	Membrane protein of unknown function; Region: DUF360; pfam04020
1429244004397	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1429244004398	MutS domain III; Region: MutS_III; pfam05192
1429244004399	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
1429244004400	Walker A/P-loop; other site
1429244004401	ATP binding site [chemical binding]; other site
1429244004402	Q-loop/lid; other site
1429244004403	ABC transporter signature motif; other site
1429244004404	Walker B; other site
1429244004405	D-loop; other site
1429244004406	H-loop/switch region; other site
1429244004407	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
1429244004408	Smr domain; Region: Smr; pfam01713
1429244004409	Predicted membrane protein [Function unknown]; Region: COG3766
1429244004410	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1429244004411	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1429244004412	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244004413	putative substrate translocation pore; other site
1429244004414	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1429244004415	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1429244004416	Coat F domain; Region: Coat_F; pfam07875
1429244004417	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1429244004418	AsnC family; Region: AsnC_trans_reg; pfam01037
1429244004419	hypothetical protein; Validated; Region: PRK07682
1429244004420	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244004421	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244004422	homodimer interface [polypeptide binding]; other site
1429244004423	catalytic residue [active]
1429244004424	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1429244004425	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1429244004426	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1429244004427	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244004428	RNA binding surface [nucleotide binding]; other site
1429244004429	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1429244004430	active site
1429244004431	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
1429244004432	ArsC family; Region: ArsC; pfam03960
1429244004433	putative ArsC-like catalytic residues; other site
1429244004434	putative TRX-like catalytic residues [active]
1429244004435	5'-3' exonuclease; Region: 53EXOc; smart00475
1429244004436	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1429244004437	active site
1429244004438	metal binding site 1 [ion binding]; metal-binding site
1429244004439	putative 5' ssDNA interaction site; other site
1429244004440	metal binding site 3; metal-binding site
1429244004441	metal binding site 2 [ion binding]; metal-binding site
1429244004442	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1429244004443	putative DNA binding site [nucleotide binding]; other site
1429244004444	putative metal binding site [ion binding]; other site
1429244004445	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1429244004446	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244004447	nucleotide binding site [chemical binding]; other site
1429244004448	HRDC domain; Region: HRDC; pfam00570
1429244004449	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1429244004450	Thermotoga maritima CorA-like family; Region: TmCorA-like; cd12822
1429244004451	oligomer interface [polypeptide binding]; other site
1429244004452	metal binding site [ion binding]; metal-binding site
1429244004453	metal binding site [ion binding]; metal-binding site
1429244004454	putative Cl binding site [ion binding]; other site
1429244004455	aspartate ring; other site
1429244004456	basic sphincter; other site
1429244004457	hydrophobic gate; other site
1429244004458	periplasmic entrance; other site
1429244004459	Homoserine O-succinyltransferase; Region: HTS; pfam04204
1429244004460	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1429244004461	proposed active site lysine [active]
1429244004462	conserved cys residue [active]
1429244004463	cystathionine gamma-synthase; Reviewed; Region: PRK08247
1429244004464	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1429244004465	homodimer interface [polypeptide binding]; other site
1429244004466	substrate-cofactor binding pocket; other site
1429244004467	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244004468	catalytic residue [active]
1429244004469	cystathionine beta-lyase; Provisional; Region: PRK08064
1429244004470	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1429244004471	homodimer interface [polypeptide binding]; other site
1429244004472	substrate-cofactor binding pocket; other site
1429244004473	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244004474	catalytic residue [active]
1429244004475	menaquinone biosynthesis protein, SCO4550 family; Region: mena_SCO4550; TIGR03699
1429244004476	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244004477	FeS/SAM binding site; other site
1429244004478	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1429244004479	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1429244004480	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1429244004481	Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism]; Region: COG0490
1429244004482	TrkA-C domain; Region: TrkA_C; pfam02080
1429244004483	YtxC-like family; Region: YtxC; pfam08812
1429244004484	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1429244004485	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1429244004486	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1429244004487	protein binding site [polypeptide binding]; other site
1429244004488	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244004489	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244004490	active site
1429244004491	phosphorylation site [posttranslational modification]
1429244004492	intermolecular recognition site; other site
1429244004493	dimerization interface [polypeptide binding]; other site
1429244004494	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244004495	DNA binding site [nucleotide binding]
1429244004496	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244004497	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244004498	dimerization interface [polypeptide binding]; other site
1429244004499	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244004500	dimer interface [polypeptide binding]; other site
1429244004501	phosphorylation site [posttranslational modification]
1429244004502	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244004503	ATP binding site [chemical binding]; other site
1429244004504	Mg2+ binding site [ion binding]; other site
1429244004505	G-X-G motif; other site
1429244004506	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1429244004507	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1429244004508	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
1429244004509	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1429244004510	glutamine synthetase, type I; Region: GlnA; TIGR00653
1429244004511	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1429244004512	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1429244004513	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1429244004514	homodimer interface [polypeptide binding]; other site
1429244004515	substrate-cofactor binding pocket; other site
1429244004516	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244004517	catalytic residue [active]
1429244004518	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1429244004519	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1429244004520	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1429244004521	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1429244004522	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244004523	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244004524	active site
1429244004525	phosphorylation site [posttranslational modification]
1429244004526	intermolecular recognition site; other site
1429244004527	dimerization interface [polypeptide binding]; other site
1429244004528	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244004529	DNA binding residues [nucleotide binding]
1429244004530	dimerization interface [polypeptide binding]; other site
1429244004531	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244004532	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1429244004533	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244004534	homodimer interface [polypeptide binding]; other site
1429244004535	catalytic residue [active]
1429244004536	Uncharacterized conserved protein (DUF2161); Region: DUF2161; cl02298
1429244004537	Putative Ser protein kinase [Signal transduction mechanisms]; Region: PrkA; COG2766
1429244004538	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1429244004539	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1429244004540	heme-binding site [chemical binding]; other site
1429244004541	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244004542	dimer interface [polypeptide binding]; other site
1429244004543	putative CheW interface [polypeptide binding]; other site
1429244004544	spore coat protein YsxE; Region: spore_ysxE; TIGR02904
1429244004545	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244004546	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244004547	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1429244004548	active site
1429244004549	ATP binding site [chemical binding]; other site
1429244004550	Predicted membrane protein [Function unknown]; Region: COG3212
1429244004551	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1429244004552	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1429244004553	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1429244004554	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244004555	HAMP domain; Region: HAMP; pfam00672
1429244004556	dimerization interface [polypeptide binding]; other site
1429244004557	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244004558	dimer interface [polypeptide binding]; other site
1429244004559	phosphorylation site [posttranslational modification]
1429244004560	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244004561	ATP binding site [chemical binding]; other site
1429244004562	Mg2+ binding site [ion binding]; other site
1429244004563	G-X-G motif; other site
1429244004564	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244004565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244004566	active site
1429244004567	phosphorylation site [posttranslational modification]
1429244004568	intermolecular recognition site; other site
1429244004569	dimerization interface [polypeptide binding]; other site
1429244004570	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244004571	DNA binding site [nucleotide binding]
1429244004572	hypothetical protein; Provisional; Region: PRK10481
1429244004573	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1429244004574	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1429244004575	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1429244004576	DRTGG domain; Region: DRTGG; pfam07085
1429244004577	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1429244004578	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1429244004579	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244004580	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244004581	active site
1429244004582	phosphorylation site [posttranslational modification]
1429244004583	intermolecular recognition site; other site
1429244004584	dimerization interface [polypeptide binding]; other site
1429244004585	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244004586	DNA binding site [nucleotide binding]
1429244004587	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244004588	HAMP domain; Region: HAMP; pfam00672
1429244004589	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244004590	dimer interface [polypeptide binding]; other site
1429244004591	phosphorylation site [posttranslational modification]
1429244004592	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244004593	ATP binding site [chemical binding]; other site
1429244004594	Mg2+ binding site [ion binding]; other site
1429244004595	G-X-G motif; other site
1429244004596	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
1429244004597	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1429244004598	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1429244004599	[2Fe-2S] cluster binding site [ion binding]; other site
1429244004600	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1429244004601	hydrophobic ligand binding site; other site
1429244004602	SpoVR like protein; Region: SpoVR; pfam04293
1429244004603	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1429244004604	sporulation protein YhbH; Region: spore_yhbH; TIGR02877
1429244004605	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244004606	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244004607	active site
1429244004608	phosphorylation site [posttranslational modification]
1429244004609	intermolecular recognition site; other site
1429244004610	dimerization interface [polypeptide binding]; other site
1429244004611	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244004612	DNA binding site [nucleotide binding]
1429244004613	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244004614	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244004615	dimer interface [polypeptide binding]; other site
1429244004616	phosphorylation site [posttranslational modification]
1429244004617	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244004618	ATP binding site [chemical binding]; other site
1429244004619	Mg2+ binding site [ion binding]; other site
1429244004620	G-X-G motif; other site
1429244004621	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244004622	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
1429244004623	Walker A/P-loop; other site
1429244004624	ATP binding site [chemical binding]; other site
1429244004625	Q-loop/lid; other site
1429244004626	ABC transporter signature motif; other site
1429244004627	Walker B; other site
1429244004628	D-loop; other site
1429244004629	H-loop/switch region; other site
1429244004630	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
1429244004631	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244004632	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
1429244004633	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244004634	Lanthionine synthetase C-like protein; Region: LANC_like; pfam05147
1429244004635	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
1429244004636	active site
1429244004637	zinc binding site [ion binding]; other site
1429244004638	Lanthionine synthetase C-like protein; Region: LANC_like; pfam05147
1429244004639	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
1429244004640	active site
1429244004641	zinc binding site [ion binding]; other site
1429244004642	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244004643	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244004644	DNA binding site [nucleotide binding]
1429244004645	Lantibiotic dehydratase, N terminus; Region: Lant_dehyd_N; pfam04737
1429244004646	Lantibiotic dehydratase, C terminus; Region: Lant_dehyd_C; pfam04738
1429244004647	thiopeptide-type bacteriocin biosynthesis domain; Region: thiopep_ocin; TIGR03891
1429244004648	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244004649	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244004650	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244004651	Walker A/P-loop; other site
1429244004652	ATP binding site [chemical binding]; other site
1429244004653	Q-loop/lid; other site
1429244004654	ABC transporter signature motif; other site
1429244004655	Walker B; other site
1429244004656	D-loop; other site
1429244004657	H-loop/switch region; other site
1429244004658	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
1429244004659	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1429244004660	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
1429244004661	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244004662	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244004663	putative substrate translocation pore; other site
1429244004664	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1429244004665	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244004666	non-specific DNA binding site [nucleotide binding]; other site
1429244004667	salt bridge; other site
1429244004668	sequence-specific DNA binding site [nucleotide binding]; other site
1429244004669	Cupin domain; Region: Cupin_2; pfam07883
1429244004670	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1429244004671	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
1429244004672	active site
1429244004673	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
1429244004674	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1429244004675	putative sugar binding sites [chemical binding]; other site
1429244004676	Q-X-W motif; other site
1429244004677	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1429244004678	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1429244004679	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1429244004680	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1429244004681	active site
1429244004682	S-layer homology domain; Region: SLH; pfam00395
1429244004683	S-layer homology domain; Region: SLH; pfam00395
1429244004684	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1429244004685	active site
1429244004686	EDD domain protein, DegV family; Region: DegV; TIGR00762
1429244004687	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1429244004688	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
1429244004689	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1429244004690	active site
1429244004691	NTP binding site [chemical binding]; other site
1429244004692	metal binding triad [ion binding]; metal-binding site
1429244004693	KNTase C-terminal domain; Region: KNTase_C; pfam07827
1429244004694	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1429244004695	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1429244004696	ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FecB; COG4594
1429244004697	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1429244004698	siderophore binding site; other site
1429244004699	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244004700	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244004701	ABC-ATPase subunit  interface; other site
1429244004702	dimer interface [polypeptide binding]; other site
1429244004703	putative PBP binding regions; other site
1429244004704	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1429244004705	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244004706	ABC-ATPase subunit  interface; other site
1429244004707	dimer interface [polypeptide binding]; other site
1429244004708	putative PBP binding regions; other site
1429244004709	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244004710	dimerization interface [polypeptide binding]; other site
1429244004711	putative DNA binding site [nucleotide binding]; other site
1429244004712	putative Zn2+ binding site [ion binding]; other site
1429244004713	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244004714	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244004715	putative substrate translocation pore; other site
1429244004716	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244004717	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1429244004718	active site
1429244004719	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244004720	Coenzyme A binding pocket [chemical binding]; other site
1429244004721	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244004722	non-specific DNA binding site [nucleotide binding]; other site
1429244004723	salt bridge; other site
1429244004724	sequence-specific DNA binding site [nucleotide binding]; other site
1429244004725	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244004726	non-specific DNA binding site [nucleotide binding]; other site
1429244004727	salt bridge; other site
1429244004728	sequence-specific DNA binding site [nucleotide binding]; other site
1429244004729	AAA domain; Region: AAA_13; pfam13166
1429244004730	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1429244004731	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
1429244004732	Proteins of 100 residues with WXG; Region: WXG100; pfam06013
1429244004733	Restriction endonuclease; Region: Mrr_cat; pfam04471
1429244004734	WXG100 family type VII secretion target; Region: WXG100_ESAT6; TIGR03930
1429244004735	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1429244004736	Domain of unknown function (DUF1805); Region: DUF1805; cl01339
1429244004737	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1429244004738	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
1429244004739	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1429244004740	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244004741	Ferritin-like domain; Region: Ferritin; pfam00210
1429244004742	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1429244004743	dimerization interface [polypeptide binding]; other site
1429244004744	DPS ferroxidase diiron center [ion binding]; other site
1429244004745	ion pore; other site
1429244004746	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1429244004747	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1429244004748	Walker A/P-loop; other site
1429244004749	ATP binding site [chemical binding]; other site
1429244004750	Q-loop/lid; other site
1429244004751	ABC transporter signature motif; other site
1429244004752	Walker B; other site
1429244004753	D-loop; other site
1429244004754	H-loop/switch region; other site
1429244004755	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
1429244004756	FeS assembly protein SufD; Region: sufD; TIGR01981
1429244004757	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1429244004758	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1429244004759	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244004760	catalytic residue [active]
1429244004761	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1429244004762	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1429244004763	trimerization site [polypeptide binding]; other site
1429244004764	active site
1429244004765	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1429244004766	FeS assembly protein SufB; Region: sufB; TIGR01980
1429244004767	YmaF family; Region: YmaF; pfam12788
1429244004768	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1429244004769	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244004770	Zn2+ binding site [ion binding]; other site
1429244004771	Mg2+ binding site [ion binding]; other site
1429244004772	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1429244004773	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1429244004774	active site
1429244004775	metal binding site [ion binding]; metal-binding site
1429244004776	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1429244004777	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1429244004778	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244004779	Zn2+ binding site [ion binding]; other site
1429244004780	Mg2+ binding site [ion binding]; other site
1429244004781	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1429244004782	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244004783	FeS/SAM binding site; other site
1429244004784	YfkB-like domain; Region: YfkB; pfam08756
1429244004785	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1429244004786	Domain of unknown function DUF21; Region: DUF21; pfam01595
1429244004787	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1429244004788	Transporter associated domain; Region: CorC_HlyC; smart01091
1429244004789	Spore coat associated protein JA (CotJA); Region: CotJA; pfam11007
1429244004790	CotJB protein; Region: CotJB; pfam12652
1429244004791	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1429244004792	dimanganese center [ion binding]; other site
1429244004793	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244004794	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1429244004795	putative metal binding site; other site
1429244004796	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244004797	binding surface
1429244004798	TPR motif; other site
1429244004799	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244004800	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244004801	active site
1429244004802	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1429244004803	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1429244004804	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244004805	S-adenosylmethionine binding site [chemical binding]; other site
1429244004806	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1429244004807	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244004808	motif II; other site
1429244004809	alpha-L-glutamate ligases, RimK family; Region: rimK_fam; TIGR00768
1429244004810	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244004811	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244004812	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244004813	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244004814	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244004815	hypothetical protein; Provisional; Region: PRK13676
1429244004816	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
1429244004817	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244004818	DNA-binding site [nucleotide binding]; DNA binding site
1429244004819	DRTGG domain; Region: DRTGG; pfam07085
1429244004820	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1429244004821	Thioesterase superfamily; Region: 4HBT; pfam03061
1429244004822	Sporulation protein YtrH; Region: Spore_YtrH; pfam14034
1429244004823	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1429244004824	tetramer interfaces [polypeptide binding]; other site
1429244004825	binuclear metal-binding site [ion binding]; other site
1429244004826	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1429244004827	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
1429244004828	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1429244004829	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1429244004830	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1429244004831	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
1429244004832	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1429244004833	domain interfaces; other site
1429244004834	active site
1429244004835	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244004836	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244004837	putative DNA binding site [nucleotide binding]; other site
1429244004838	putative Zn2+ binding site [ion binding]; other site
1429244004839	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244004840	dimerization interface [polypeptide binding]; other site
1429244004841	PBP superfamily domain; Region: PBP_like_2; cl17296
1429244004842	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1429244004843	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1429244004844	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244004845	dimer interface [polypeptide binding]; other site
1429244004846	conserved gate region; other site
1429244004847	putative PBP binding loops; other site
1429244004848	ABC-ATPase subunit interface; other site
1429244004849	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1429244004850	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244004851	dimer interface [polypeptide binding]; other site
1429244004852	conserved gate region; other site
1429244004853	putative PBP binding loops; other site
1429244004854	ABC-ATPase subunit interface; other site
1429244004855	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1429244004856	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1429244004857	Walker A/P-loop; other site
1429244004858	ATP binding site [chemical binding]; other site
1429244004859	Q-loop/lid; other site
1429244004860	ABC transporter signature motif; other site
1429244004861	Walker B; other site
1429244004862	D-loop; other site
1429244004863	H-loop/switch region; other site
1429244004864	Pectic acid lyase; Region: Pec_lyase; pfam09492
1429244004865	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1429244004866	active site
1429244004867	FxsA cytoplasmic membrane protein; Region: FxsA; pfam04186
1429244004868	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1429244004869	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1429244004870	Bacillus subtilis (Bs) citrate synthase (CS)-II_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BSuCS-II_like; cd06110
1429244004871	dimer interface [polypeptide binding]; other site
1429244004872	Citrate synthase; Region: Citrate_synt; pfam00285
1429244004873	active site
1429244004874	citrylCoA binding site [chemical binding]; other site
1429244004875	oxalacetate/citrate binding site [chemical binding]; other site
1429244004876	coenzyme A binding site [chemical binding]; other site
1429244004877	catalytic triad [active]
1429244004878	isocitrate dehydrogenase; Validated; Region: PRK06451
1429244004879	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1429244004880	malate dehydrogenase; Reviewed; Region: PRK06223
1429244004881	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1429244004882	NAD(P) binding site [chemical binding]; other site
1429244004883	dimer interface [polypeptide binding]; other site
1429244004884	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244004885	substrate binding site [chemical binding]; other site
1429244004886	short chain dehydrogenase; Provisional; Region: PRK06701
1429244004887	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1429244004888	NAD binding site [chemical binding]; other site
1429244004889	metal binding site [ion binding]; metal-binding site
1429244004890	active site
1429244004891	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1429244004892	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244004893	dimerization interface [polypeptide binding]; other site
1429244004894	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1429244004895	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244004896	dimer interface [polypeptide binding]; other site
1429244004897	phosphorylation site [posttranslational modification]
1429244004898	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244004899	ATP binding site [chemical binding]; other site
1429244004900	Mg2+ binding site [ion binding]; other site
1429244004901	G-X-G motif; other site
1429244004902	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244004903	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244004904	active site
1429244004905	phosphorylation site [posttranslational modification]
1429244004906	intermolecular recognition site; other site
1429244004907	dimerization interface [polypeptide binding]; other site
1429244004908	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244004909	DNA binding site [nucleotide binding]
1429244004910	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1429244004911	FOG: CBS domain [General function prediction only]; Region: COG0517
1429244004912	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244004913	dimer interface [polypeptide binding]; other site
1429244004914	putative CheW interface [polypeptide binding]; other site
1429244004915	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1429244004916	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1429244004917	Walker A/P-loop; other site
1429244004918	ATP binding site [chemical binding]; other site
1429244004919	Q-loop/lid; other site
1429244004920	ABC transporter signature motif; other site
1429244004921	Walker B; other site
1429244004922	D-loop; other site
1429244004923	H-loop/switch region; other site
1429244004924	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1429244004925	PhoU domain; Region: PhoU; pfam01895
1429244004926	PhoU domain; Region: PhoU; pfam01895
1429244004927	DNA polymerase I; Provisional; Region: PRK05755
1429244004928	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1429244004929	active site
1429244004930	metal binding site 1 [ion binding]; metal-binding site
1429244004931	putative 5' ssDNA interaction site; other site
1429244004932	metal binding site 3; metal-binding site
1429244004933	metal binding site 2 [ion binding]; metal-binding site
1429244004934	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1429244004935	putative DNA binding site [nucleotide binding]; other site
1429244004936	putative metal binding site [ion binding]; other site
1429244004937	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
1429244004938	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1429244004939	active site
1429244004940	DNA binding site [nucleotide binding]
1429244004941	catalytic site [active]
1429244004942	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1429244004943	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1429244004944	DNA binding site [nucleotide binding]
1429244004945	catalytic residue [active]
1429244004946	H2TH interface [polypeptide binding]; other site
1429244004947	putative catalytic residues [active]
1429244004948	turnover-facilitating residue; other site
1429244004949	intercalation triad [nucleotide binding]; other site
1429244004950	8OG recognition residue [nucleotide binding]; other site
1429244004951	putative reading head residues; other site
1429244004952	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1429244004953	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1429244004954	putative sporulation protein YtaF; Region: spore_YtaF; TIGR02840
1429244004955	Domain of unknown function DUF; Region: DUF204; pfam02659
1429244004956	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1429244004957	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1429244004958	CoA-binding site [chemical binding]; other site
1429244004959	ATP-binding [chemical binding]; other site
1429244004960	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1429244004961	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1429244004962	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1429244004963	catalytic residue [active]
1429244004964	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1429244004965	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1429244004966	ATP cone domain; Region: ATP-cone; pfam03477
1429244004967	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1429244004968	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1429244004969	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244004970	Coenzyme A binding pocket [chemical binding]; other site
1429244004971	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244004972	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1429244004973	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1429244004974	DNA binding residues [nucleotide binding]
1429244004975	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
1429244004976	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244004977	FeS/SAM binding site; other site
1429244004978	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1429244004979	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244004980	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244004981	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1429244004982	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244004983	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1429244004984	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244004985	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244004986	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244004987	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244004988	intersubunit interface [polypeptide binding]; other site
1429244004989	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1429244004990	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244004991	dimerization interface [polypeptide binding]; other site
1429244004992	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244004993	dimer interface [polypeptide binding]; other site
1429244004994	putative CheW interface [polypeptide binding]; other site
1429244004995	Domain of unknown function (DUF4183); Region: DUF4183; pfam13799
1429244004996	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
1429244004997	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1429244004998	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1429244004999	ligand binding site [chemical binding]; other site
1429244005000	flexible hinge region; other site
1429244005001	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1429244005002	putative switch regulator; other site
1429244005003	non-specific DNA interactions [nucleotide binding]; other site
1429244005004	DNA binding site [nucleotide binding]
1429244005005	sequence specific DNA binding site [nucleotide binding]; other site
1429244005006	putative cAMP binding site [chemical binding]; other site
1429244005007	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1429244005008	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1429244005009	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1429244005010	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1429244005011	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1429244005012	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1429244005013	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1429244005014	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1429244005015	putative substrate binding site [chemical binding]; other site
1429244005016	putative ATP binding site [chemical binding]; other site
1429244005017	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1429244005018	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244005019	active site
1429244005020	phosphorylation site [posttranslational modification]
1429244005021	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1429244005022	active site
1429244005023	P-loop; other site
1429244005024	phosphorylation site [posttranslational modification]
1429244005025	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1429244005026	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244005027	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244005028	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244005029	dimerization interface [polypeptide binding]; other site
1429244005030	active site 1 [active]
1429244005031	dimer interface [polypeptide binding]; other site
1429244005032	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1429244005033	hexamer interface [polypeptide binding]; other site
1429244005034	active site 2 [active]
1429244005035	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1429244005036	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1429244005037	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244005038	DNA-binding site [nucleotide binding]; DNA binding site
1429244005039	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1429244005040	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1429244005041	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1429244005042	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1429244005043	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1429244005044	GntP family permease; Region: GntP_permease; pfam02447
1429244005045	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244005046	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244005047	PRD domain; Region: PRD; pfam00874
1429244005048	PRD domain; Region: PRD; pfam00874
1429244005049	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244005050	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244005051	active site turn [active]
1429244005052	phosphorylation site [posttranslational modification]
1429244005053	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244005054	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244005055	HPr interaction site; other site
1429244005056	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244005057	active site
1429244005058	phosphorylation site [posttranslational modification]
1429244005059	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244005060	beta-galactosidase; Region: BGL; TIGR03356
1429244005061	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244005062	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244005063	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244005064	dimerization interface [polypeptide binding]; other site
1429244005065	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1429244005066	substrate binding site [chemical binding]; other site
1429244005067	THF binding site; other site
1429244005068	zinc-binding site [ion binding]; other site
1429244005069	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244005070	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244005071	non-specific DNA binding site [nucleotide binding]; other site
1429244005072	salt bridge; other site
1429244005073	sequence-specific DNA binding site [nucleotide binding]; other site
1429244005074	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244005075	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244005076	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1429244005077	outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300
1429244005078	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1429244005079	heat shock protein 90; Provisional; Region: PRK05218
1429244005080	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244005081	ATP binding site [chemical binding]; other site
1429244005082	Mg2+ binding site [ion binding]; other site
1429244005083	G-X-G motif; other site
1429244005084	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
1429244005085	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
1429244005086	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244005087	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
1429244005088	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
1429244005089	dimer interface [polypeptide binding]; other site
1429244005090	active site
1429244005091	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1429244005092	catalytic residues [active]
1429244005093	substrate binding site [chemical binding]; other site
1429244005094	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1429244005095	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244005096	Coenzyme A binding pocket [chemical binding]; other site
1429244005097	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1429244005098	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244005099	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244005100	dimerization interface [polypeptide binding]; other site
1429244005101	putative DNA binding site [nucleotide binding]; other site
1429244005102	putative Zn2+ binding site [ion binding]; other site
1429244005103	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
1429244005104	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
1429244005105	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
1429244005106	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
1429244005107	Glycerol-1-phosphate dehydrogenase (G1PDH) catalyzes the reversible reduction of dihydroxyacetone phosphate (DHAP) to glycerol-1-phosphate (G1P) in an NADH-dependent manner; Region: G1PDH; cd08175
1429244005108	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1429244005109	active site
1429244005110	metal binding site [ion binding]; metal-binding site
1429244005111	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1429244005112	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244005113	DNA-binding site [nucleotide binding]; DNA binding site
1429244005114	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1429244005115	Ligand-binding domain of DNA transcription repressor specific for arabinose (AraR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AraR; cd01541
1429244005116	putative dimerization interface [polypeptide binding]; other site
1429244005117	putative ligand binding site [chemical binding]; other site
1429244005118	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1429244005119	ribulokinase; Provisional; Region: PRK04123
1429244005120	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1429244005121	N- and C-terminal domain interface [polypeptide binding]; other site
1429244005122	active site
1429244005123	MgATP binding site [chemical binding]; other site
1429244005124	catalytic site [active]
1429244005125	metal binding site [ion binding]; metal-binding site
1429244005126	carbohydrate binding site [chemical binding]; other site
1429244005127	homodimer interface [polypeptide binding]; other site
1429244005128	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1429244005129	non-specific DNA binding site [nucleotide binding]; other site
1429244005130	salt bridge; other site
1429244005131	sequence-specific DNA binding site [nucleotide binding]; other site
1429244005132	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1429244005133	RHS Repeat; Region: RHS_repeat; pfam05593
1429244005134	RHS Repeat; Region: RHS_repeat; pfam05593
1429244005135	RHS Repeat; Region: RHS_repeat; pfam05593
1429244005136	RHS Repeat; Region: RHS_repeat; pfam05593
1429244005137	RHS Repeat; Region: RHS_repeat; cl11982
1429244005138	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1429244005139	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244005140	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1429244005141	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1429244005142	NodB motif; other site
1429244005143	active site
1429244005144	catalytic site [active]
1429244005145	Zn binding site [ion binding]; other site
1429244005146	Holin family; Region: Phage_holin_4; pfam05105
1429244005147	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
1429244005148	Uncharacterized conserved protein [Function unknown]; Region: COG2445
1429244005149	Predicted transcriptional regulator [Transcription]; Region: COG2345
1429244005150	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244005151	putative DNA binding site [nucleotide binding]; other site
1429244005152	putative Zn2+ binding site [ion binding]; other site
1429244005153	YtxH-like protein; Region: YtxH; pfam12732
1429244005154	glutamate racemase; Provisional; Region: PRK00865
1429244005155	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244005156	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244005157	Peptidase M14 carboxypeptidase family-like domain of Endopeptidase I; Region: M14_Endopeptidase_I; cd06229
1429244005158	putative active site [active]
1429244005159	Zn binding site [ion binding]; other site
1429244005160	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1429244005161	Protein of unknown function (DUF1450); Region: DUF1450; cl11488
1429244005162	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1429244005163	Sulfatase; Region: Sulfatase; pfam00884
1429244005164	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1429244005165	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1429244005166	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1429244005167	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1429244005168	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1429244005169	drug efflux system protein MdtG; Provisional; Region: PRK09874
1429244005170	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005171	putative substrate translocation pore; other site
1429244005172	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1429244005173	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1429244005174	substrate binding site [chemical binding]; other site
1429244005175	active site
1429244005176	ferrochelatase; Provisional; Region: PRK12435
1429244005177	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1429244005178	C-terminal domain interface [polypeptide binding]; other site
1429244005179	active site
1429244005180	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1429244005181	active site
1429244005182	N-terminal domain interface [polypeptide binding]; other site
1429244005183	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
1429244005184	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1429244005185	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
1429244005186	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1429244005187	putative active site [active]
1429244005188	putative metal binding site [ion binding]; other site
1429244005189	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1429244005190	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1429244005191	active site
1429244005192	catalytic site [active]
1429244005193	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1429244005194	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1429244005195	Integral membrane protein DUF92; Region: DUF92; pfam01940
1429244005196	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244005197	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244005198	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1429244005199	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244005200	Walker A/P-loop; other site
1429244005201	ATP binding site [chemical binding]; other site
1429244005202	Q-loop/lid; other site
1429244005203	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244005204	ABC transporter signature motif; other site
1429244005205	Walker B; other site
1429244005206	D-loop; other site
1429244005207	ABC transporter; Region: ABC_tran_2; pfam12848
1429244005208	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244005209	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244005210	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244005211	active site
1429244005212	catalytic tetrad [active]
1429244005213	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1429244005214	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244005215	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1429244005216	dimerization interface [polypeptide binding]; other site
1429244005217	substrate binding pocket [chemical binding]; other site
1429244005218	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1429244005219	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
1429244005220	putative oligomer interface [polypeptide binding]; other site
1429244005221	putative active site [active]
1429244005222	metal binding site [ion binding]; metal-binding site
1429244005223	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
1429244005224	oligoendopeptidase F; Region: pepF; TIGR00181
1429244005225	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1429244005226	active site
1429244005227	Zn binding site [ion binding]; other site
1429244005228	cspA; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244005229	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1429244005230	DNA-binding site [nucleotide binding]; DNA binding site
1429244005231	RNA-binding motif; other site
1429244005232	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1429244005233	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1429244005234	Protein of unknown function (DUF2600); Region: DUF2600; pfam10776
1429244005235	6-phosphofructokinase; Provisional; Region: PRK03202
1429244005236	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1429244005237	active site
1429244005238	ADP/pyrophosphate binding site [chemical binding]; other site
1429244005239	dimerization interface [polypeptide binding]; other site
1429244005240	allosteric effector site; other site
1429244005241	fructose-1,6-bisphosphate binding site; other site
1429244005242	Protein of unknown function (DUF3906); Region: DUF3906; pfam13046
1429244005243	multidrug efflux protein; Reviewed; Region: PRK01766
1429244005244	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1429244005245	cation binding site [ion binding]; other site
1429244005246	Putative glycosyl hydrolase domain; Region: DUF4015; pfam13200
1429244005247	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1429244005248	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244005249	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244005250	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1429244005251	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1429244005252	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1429244005253	ATP binding site [chemical binding]; other site
1429244005254	Mg++ binding site [ion binding]; other site
1429244005255	motif III; other site
1429244005256	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244005257	nucleotide binding region [chemical binding]; other site
1429244005258	ATP-binding site [chemical binding]; other site
1429244005259	Protein of unknown function, DUF624; Region: DUF624; cl02369
1429244005260	Protein of unknown function (DUF1499); Region: DUF1499; cl01841
1429244005261	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1429244005262	dimer interface [polypeptide binding]; other site
1429244005263	catalytic triad [active]
1429244005264	peroxidatic and resolving cysteines [active]
1429244005265	Rhomboid family; Region: Rhomboid; pfam01694
1429244005266	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244005267	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244005268	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1429244005269	putative dimerization interface [polypeptide binding]; other site
1429244005270	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
1429244005271	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1429244005272	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244005273	DNA binding residues [nucleotide binding]
1429244005274	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1429244005275	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1429244005276	metal binding triad; other site
1429244005277	hypothetical protein; Provisional; Region: PRK07740
1429244005278	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1429244005279	active site
1429244005280	catalytic site [active]
1429244005281	substrate binding site [chemical binding]; other site
1429244005282	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1429244005283	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1429244005284	catalytic residues [active]
1429244005285	putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional; Region: PRK12344
1429244005286	Desulfobacterium autotrophicum LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA3; cd07941
1429244005287	active site
1429244005288	catalytic residues [active]
1429244005289	metal binding site [ion binding]; metal-binding site
1429244005290	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1429244005291	DNA polymerase IV; Validated; Region: PRK01810
1429244005292	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1429244005293	active site
1429244005294	DNA binding site [nucleotide binding]
1429244005295	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1429244005296	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
1429244005297	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1429244005298	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1429244005299	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1429244005300	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1429244005301	quinone interaction residues [chemical binding]; other site
1429244005302	active site
1429244005303	catalytic residues [active]
1429244005304	FMN binding site [chemical binding]; other site
1429244005305	substrate binding site [chemical binding]; other site
1429244005306	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1429244005307	synthetase active site [active]
1429244005308	NTP binding site [chemical binding]; other site
1429244005309	metal binding site [ion binding]; metal-binding site
1429244005310	Domain of unknown function (DUF309); Region: DUF309; pfam03745
1429244005311	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244005312	catalytic residues [active]
1429244005313	NOL1/NOP2/sun family; Region: Nol1_Nop2_Fmu; pfam01189
1429244005314	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244005315	S-adenosylmethionine binding site [chemical binding]; other site
1429244005316	Uncharacterized conserved protein [Function unknown]; Region: COG3270
1429244005317	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1429244005318	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244005319	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1429244005320	RNA binding surface [nucleotide binding]; other site
1429244005321	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1429244005322	active site
1429244005323	uracil binding [chemical binding]; other site
1429244005324	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244005325	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244005326	metal binding site [ion binding]; metal-binding site
1429244005327	active site
1429244005328	I-site; other site
1429244005329	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244005330	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244005331	Uncharacterized membrane protein [Function unknown]; Region: COG3949
1429244005332	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1429244005333	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1429244005334	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244005335	active site
1429244005336	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1429244005337	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1429244005338	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005339	putative substrate translocation pore; other site
1429244005340	Helix-Turn-Helix DNA binding domain of the BltR transcription regulator; Region: HTH_BltR; cd04782
1429244005341	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244005342	DNA binding residues [nucleotide binding]
1429244005343	dimer interface [polypeptide binding]; other site
1429244005344	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1429244005345	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1429244005346	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1429244005347	NodB motif; other site
1429244005348	putative active site [active]
1429244005349	putative catalytic site [active]
1429244005350	Zn binding site [ion binding]; other site
1429244005351	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1429244005352	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1429244005353	active site
1429244005354	metal binding site [ion binding]; metal-binding site
1429244005355	YqzE-like protein; Region: YqzE; pfam14038
1429244005356	Bacterial protein YqhG of unknown function; Region: YqhG; pfam11079
1429244005357	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1429244005358	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244005359	ATP binding site [chemical binding]; other site
1429244005360	putative Mg++ binding site [ion binding]; other site
1429244005361	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244005362	nucleotide binding region [chemical binding]; other site
1429244005363	ATP-binding site [chemical binding]; other site
1429244005364	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244005365	salt bridge; other site
1429244005366	non-specific DNA binding site [nucleotide binding]; other site
1429244005367	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244005368	sequence-specific DNA binding site [nucleotide binding]; other site
1429244005369	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1429244005370	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1429244005371	dimer interface [polypeptide binding]; other site
1429244005372	active site
1429244005373	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
1429244005374	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244005375	Coenzyme A binding pocket [chemical binding]; other site
1429244005376	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244005377	HTH domain; Region: HTH_11; pfam08279
1429244005378	WYL domain; Region: WYL; pfam13280
1429244005379	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
1429244005380	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
1429244005381	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005382	putative substrate translocation pore; other site
1429244005383	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244005384	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244005385	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
1429244005386	hypothetical protein; Validated; Region: PRK07682
1429244005387	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244005388	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244005389	homodimer interface [polypeptide binding]; other site
1429244005390	catalytic residue [active]
1429244005391	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244005392	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
1429244005393	Protein of unknown function (DUF1361); Region: DUF1361; cl01784
1429244005394	Predicted transcriptional regulator [Transcription]; Region: COG4189
1429244005395	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244005396	dimerization interface [polypeptide binding]; other site
1429244005397	putative DNA binding site [nucleotide binding]; other site
1429244005398	putative Zn2+ binding site [ion binding]; other site
1429244005399	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244005400	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244005401	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244005402	putative PBP binding loops; other site
1429244005403	dimer interface [polypeptide binding]; other site
1429244005404	ABC-ATPase subunit interface; other site
1429244005405	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244005406	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244005407	dimer interface [polypeptide binding]; other site
1429244005408	conserved gate region; other site
1429244005409	putative PBP binding loops; other site
1429244005410	ABC-ATPase subunit interface; other site
1429244005411	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
1429244005412	substrate binding site [chemical binding]; other site
1429244005413	active site
1429244005414	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1429244005415	active site
1429244005416	Protein of unknown function (DUF3024); Region: DUF3024; pfam11225
1429244005417	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244005418	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1429244005419	NAD(P) binding site [chemical binding]; other site
1429244005420	active site
1429244005421	hypothetical protein; Provisional; Region: PRK06922
1429244005422	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244005423	S-adenosylmethionine binding site [chemical binding]; other site
1429244005424	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
1429244005425	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1429244005426	dimer interface [polypeptide binding]; other site
1429244005427	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244005428	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244005429	MarR family; Region: MarR; pfam01047
1429244005430	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005431	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244005432	putative substrate translocation pore; other site
1429244005433	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1429244005434	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1429244005435	dimer interface [polypeptide binding]; other site
1429244005436	putative radical transfer pathway; other site
1429244005437	diiron center [ion binding]; other site
1429244005438	tyrosyl radical; other site
1429244005439	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07632
1429244005440	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1429244005441	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1429244005442	active site
1429244005443	dimer interface [polypeptide binding]; other site
1429244005444	catalytic residues [active]
1429244005445	effector binding site; other site
1429244005446	R2 peptide binding site; other site
1429244005447	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1429244005448	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1429244005449	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244005450	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244005451	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244005452	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244005453	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244005454	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244005455	DNA binding site [nucleotide binding]
1429244005456	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1429244005457	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
1429244005458	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1429244005459	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1429244005460	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244005461	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1429244005462	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244005463	nucleotide binding site [chemical binding]; other site
1429244005464	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005465	phenyl proprionate permease family protein; Region: 2A0127; TIGR00902
1429244005466	putative substrate translocation pore; other site
1429244005467	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244005468	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244005469	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244005470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244005471	dimer interface [polypeptide binding]; other site
1429244005472	conserved gate region; other site
1429244005473	putative PBP binding loops; other site
1429244005474	ABC-ATPase subunit interface; other site
1429244005475	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244005476	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244005477	dimer interface [polypeptide binding]; other site
1429244005478	conserved gate region; other site
1429244005479	ABC-ATPase subunit interface; other site
1429244005480	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1429244005481	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1429244005482	Metal-binding active site; metal-binding site
1429244005483	Protein of unknown function (DUF1361); Region: DUF1361; cl01784
1429244005484	Uncharacterized conserved protein (DUF2196); Region: DUF2196; pfam09962
1429244005485	Predicted membrane protein (DUF2238); Region: DUF2238; pfam09997
1429244005486	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244005487	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
1429244005488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005489	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244005490	putative substrate translocation pore; other site
1429244005491	Predicted membrane protein [Function unknown]; Region: COG4129
1429244005492	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1429244005493	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
1429244005494	Part of AAA domain; Region: AAA_19; pfam13245
1429244005495	Family description; Region: UvrD_C_2; pfam13538
1429244005496	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1429244005497	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244005498	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244005499	active site
1429244005500	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1429244005501	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244005502	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244005503	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244005504	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244005505	dimerization interface [polypeptide binding]; other site
1429244005506	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244005507	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244005508	dimer interface [polypeptide binding]; other site
1429244005509	putative CheW interface [polypeptide binding]; other site
1429244005510	galactoside permease; Reviewed; Region: lacY; PRK09528
1429244005511	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005512	putative substrate translocation pore; other site
1429244005513	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
1429244005514	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244005515	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244005516	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244005517	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244005518	putative alpha-glucosidase; Provisional; Region: PRK10658
1429244005519	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1429244005520	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1429244005521	active site
1429244005522	homotrimer interface [polypeptide binding]; other site
1429244005523	catalytic site [active]
1429244005524	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1429244005525	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244005526	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244005527	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1429244005528	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1429244005529	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244005530	dimerization interface [polypeptide binding]; other site
1429244005531	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244005532	dimer interface [polypeptide binding]; other site
1429244005533	putative CheW interface [polypeptide binding]; other site
1429244005534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005535	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244005536	putative substrate translocation pore; other site
1429244005537	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005538	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244005539	putative substrate translocation pore; other site
1429244005540	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244005541	MarR family; Region: MarR; pfam01047
1429244005542	MarR family; Region: MarR_2; cl17246
1429244005543	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1429244005544	active site
1429244005545	intersubunit interactions; other site
1429244005546	catalytic residue [active]
1429244005547	HTH domain; Region: HTH_11; pfam08279
1429244005548	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1429244005549	FOG: CBS domain [General function prediction only]; Region: COG0517
1429244005550	TraX protein; Region: TraX; pfam05857
1429244005551	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
1429244005552	putative active site [active]
1429244005553	putative metal binding site [ion binding]; other site
1429244005554	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244005555	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1429244005556	acyl-activating enzyme (AAE) consensus motif; other site
1429244005557	AMP binding site [chemical binding]; other site
1429244005558	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244005559	extended (e) SDRs, subgroup 1; Region: SDR_e1; cd05235
1429244005560	thioester reductase domain; Region: Thioester-redct; TIGR01746
1429244005561	putative NAD(P) binding site [chemical binding]; other site
1429244005562	active site
1429244005563	putative substrate binding site [chemical binding]; other site
1429244005564	HAMP domain; Region: HAMP; pfam00672
1429244005565	dimerization interface [polypeptide binding]; other site
1429244005566	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244005567	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244005568	dimer interface [polypeptide binding]; other site
1429244005569	putative CheW interface [polypeptide binding]; other site
1429244005570	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244005571	Coenzyme A binding pocket [chemical binding]; other site
1429244005572	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1429244005573	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244005574	active site
1429244005575	dimer interface [polypeptide binding]; other site
1429244005576	VanZ like family; Region: VanZ; pfam04892
1429244005577	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244005578	MarR family; Region: MarR; pfam01047
1429244005579	MarR family; Region: MarR_2; cl17246
1429244005580	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
1429244005581	B12 binding domain; Region: B12-binding_2; pfam02607
1429244005582	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cd02065
1429244005583	B12 binding site [chemical binding]; other site
1429244005584	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244005585	dimer interface [polypeptide binding]; other site
1429244005586	phosphorylation site [posttranslational modification]
1429244005587	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244005588	ATP binding site [chemical binding]; other site
1429244005589	Mg2+ binding site [ion binding]; other site
1429244005590	G-X-G motif; other site
1429244005591	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244005592	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244005593	active site
1429244005594	phosphorylation site [posttranslational modification]
1429244005595	intermolecular recognition site; other site
1429244005596	dimerization interface [polypeptide binding]; other site
1429244005597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005598	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244005599	putative substrate translocation pore; other site
1429244005600	Bacterial protein of unknown function (DUF925); Region: DUF925; pfam06042
1429244005601	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244005602	Coenzyme A binding pocket [chemical binding]; other site
1429244005603	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1429244005604	active site
1429244005605	oxyanion hole [active]
1429244005606	catalytic triad [active]
1429244005607	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244005608	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244005609	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1429244005610	Protein export membrane protein; Region: SecD_SecF; cl14618
1429244005611	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1429244005612	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244005613	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244005614	TPR repeat; Region: TPR_11; pfam13414
1429244005615	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244005616	binding surface
1429244005617	TPR motif; other site
1429244005618	Uncharacterized conserved protein [Function unknown]; Region: COG5646
1429244005619	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244005620	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244005621	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244005622	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1429244005623	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1429244005624	NlpC/P60 family; Region: NLPC_P60; pfam00877
1429244005625	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1429244005626	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1429244005627	dimer interface [polypeptide binding]; other site
1429244005628	active site
1429244005629	metal binding site [ion binding]; metal-binding site
1429244005630	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1429244005631	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244005632	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244005633	Old yellow enzyme (OYE)-related FMN binding domain, group 5.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_5_FMN; cd04747
1429244005634	putative active site [active]
1429244005635	putative FMN binding site [chemical binding]; other site
1429244005636	putative substrate binding site [chemical binding]; other site
1429244005637	putative catalytic residue [active]
1429244005638	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244005639	MarR family; Region: MarR_2; pfam12802
1429244005640	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1429244005641	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244005642	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1429244005643	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244005644	Coenzyme A binding pocket [chemical binding]; other site
1429244005645	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1429244005646	MarR family; Region: MarR_2; pfam12802
1429244005647	EDD domain protein, DegV family; Region: DegV; TIGR00762
1429244005648	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1429244005649	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244005650	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244005651	putative substrate translocation pore; other site
1429244005652	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1429244005653	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1429244005654	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1429244005655	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1429244005656	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244005657	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244005658	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244005659	Amino acid permease; Region: AA_permease_2; pfam13520
1429244005660	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1429244005661	Accessory gene regulator B; Region: AgrB; pfam04647
1429244005662	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1429244005663	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244005664	S-adenosylmethionine binding site [chemical binding]; other site
1429244005665	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1429244005666	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1429244005667	active site
1429244005668	(T/H)XGH motif; other site
1429244005669	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
1429244005670	Nucleoside recognition; Region: Gate; pfam07670
1429244005671	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
1429244005672	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1429244005673	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1429244005674	hypothetical protein; Provisional; Region: PRK13670
1429244005675	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
1429244005676	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1429244005677	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1429244005678	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
1429244005679	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1429244005680	active site 2 [active]
1429244005681	active site 1 [active]
1429244005682	putative phosphate acyltransferase; Provisional; Region: PRK05331
1429244005683	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1429244005684	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1429244005685	dimer interface [polypeptide binding]; other site
1429244005686	active site
1429244005687	CoA binding pocket [chemical binding]; other site
1429244005688	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1429244005689	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1429244005690	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1429244005691	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1429244005692	NAD(P) binding site [chemical binding]; other site
1429244005693	homotetramer interface [polypeptide binding]; other site
1429244005694	homodimer interface [polypeptide binding]; other site
1429244005695	active site
1429244005696	acyl carrier protein; Provisional; Region: acpP; PRK00982
1429244005697	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1429244005698	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1429244005699	dimer interface [polypeptide binding]; other site
1429244005700	active site
1429244005701	ribonuclease III; Reviewed; Region: rnc; PRK00102
1429244005702	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1429244005703	dimerization interface [polypeptide binding]; other site
1429244005704	active site
1429244005705	metal binding site [ion binding]; metal-binding site
1429244005706	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1429244005707	dsRNA binding site [nucleotide binding]; other site
1429244005708	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1429244005709	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1429244005710	Walker A/P-loop; other site
1429244005711	ATP binding site [chemical binding]; other site
1429244005712	Q-loop/lid; other site
1429244005713	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1429244005714	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1429244005715	ABC transporter signature motif; other site
1429244005716	Walker B; other site
1429244005717	D-loop; other site
1429244005718	H-loop/switch region; other site
1429244005719	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1429244005720	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1429244005721	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1429244005722	P loop; other site
1429244005723	GTP binding site [chemical binding]; other site
1429244005724	Haemolysin-III related; Region: HlyIII; cl03831
1429244005725	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1429244005726	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
1429244005727	putative DNA-binding protein; Validated; Region: PRK00118
1429244005728	signal recognition particle protein; Provisional; Region: PRK10867
1429244005729	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1429244005730	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1429244005731	P loop; other site
1429244005732	GTP binding site [chemical binding]; other site
1429244005733	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1429244005734	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1429244005735	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1429244005736	hypothetical protein; Provisional; Region: PRK00468
1429244005737	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1429244005738	RimM N-terminal domain; Region: RimM; pfam01782
1429244005739	PRC-barrel domain; Region: PRC; pfam05239
1429244005740	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1429244005741	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1429244005742	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1429244005743	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1429244005744	Catalytic site [active]
1429244005745	conjugal transfer pilin processing protease TraF; Provisional; Region: PRK13838
1429244005746	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1429244005747	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
1429244005748	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
1429244005749	GTP/Mg2+ binding site [chemical binding]; other site
1429244005750	G4 box; other site
1429244005751	G5 box; other site
1429244005752	G1 box; other site
1429244005753	Switch I region; other site
1429244005754	G2 box; other site
1429244005755	G3 box; other site
1429244005756	Switch II region; other site
1429244005757	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1429244005758	RNA/DNA hybrid binding site [nucleotide binding]; other site
1429244005759	active site
1429244005760	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1429244005761	hypothetical protein; Reviewed; Region: PRK12497
1429244005762	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1429244005763	putative FMN binding site [chemical binding]; other site
1429244005764	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1429244005765	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1429244005766	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1429244005767	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1429244005768	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1429244005769	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244005770	MarR family; Region: MarR; pfam01047
1429244005771	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1429244005772	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1429244005773	CoA-ligase; Region: Ligase_CoA; pfam00549
1429244005774	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1429244005775	CoA binding domain; Region: CoA_binding; pfam02629
1429244005776	CoA-ligase; Region: Ligase_CoA; pfam00549
1429244005777	DNA protecting protein DprA; Region: dprA; TIGR00732
1429244005778	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1429244005779	DNA topoisomerase I; Validated; Region: PRK05582
1429244005780	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1429244005781	active site
1429244005782	interdomain interaction site; other site
1429244005783	putative metal-binding site [ion binding]; other site
1429244005784	nucleotide binding site [chemical binding]; other site
1429244005785	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1429244005786	domain I; other site
1429244005787	DNA binding groove [nucleotide binding]
1429244005788	phosphate binding site [ion binding]; other site
1429244005789	domain II; other site
1429244005790	domain III; other site
1429244005791	nucleotide binding site [chemical binding]; other site
1429244005792	catalytic site [active]
1429244005793	domain IV; other site
1429244005794	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1429244005795	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1429244005796	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1429244005797	Glucose inhibited division protein A; Region: GIDA; pfam01134
1429244005798	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1429244005799	active site
1429244005800	HslU subunit interaction site [polypeptide binding]; other site
1429244005801	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1429244005802	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244005803	Walker A motif; other site
1429244005804	ATP binding site [chemical binding]; other site
1429244005805	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1429244005806	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1429244005807	Flagellar basal body protein [Cell motility and secretion]; Region: FlgB; COG1815
1429244005808	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1429244005809	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1429244005810	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1429244005811	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
1429244005812	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1429244005813	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1429244005814	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1429244005815	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1429244005816	FliG C-terminal domain; Region: FliG_C; pfam01706
1429244005817	Flagellar assembly protein FliH; Region: FliH; pfam02108
1429244005818	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07721
1429244005819	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1429244005820	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1429244005821	Walker A motif/ATP binding site; other site
1429244005822	Walker B motif; other site
1429244005823	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1429244005824	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK07720
1429244005825	Uncharacterized conserved protein [Function unknown]; Region: COG3334
1429244005826	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1429244005827	flagellar basal body rod modification protein; Provisional; Region: flgD; PRK09618
1429244005828	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1429244005829	Protein of unknown function (DUF3766); Region: DUF3766; cl11797
1429244005830	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12636
1429244005831	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1429244005832	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1429244005833	Flagellar protein (FlbD); Region: FlbD; pfam06289
1429244005834	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
1429244005835	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1429244005836	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1429244005837	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
1429244005838	CheC-like family; Region: CheC; pfam04509
1429244005839	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1429244005840	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244005841	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244005842	active site
1429244005843	phosphorylation site [posttranslational modification]
1429244005844	intermolecular recognition site; other site
1429244005845	dimerization interface [polypeptide binding]; other site
1429244005846	Flagellar biosynthesis protein, FliO; Region: FliO; cl01247
1429244005847	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1429244005848	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1429244005849	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1429244005850	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1429244005851	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1429244005852	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1429244005853	FHIPEP family; Region: FHIPEP; pfam00771
1429244005854	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
1429244005855	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1429244005856	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1429244005857	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1429244005858	P-loop; other site
1429244005859	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244005860	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244005861	active site
1429244005862	phosphorylation site [posttranslational modification]
1429244005863	intermolecular recognition site; other site
1429244005864	dimerization interface [polypeptide binding]; other site
1429244005865	CheB methylesterase; Region: CheB_methylest; pfam01339
1429244005866	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1429244005867	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1429244005868	putative binding surface; other site
1429244005869	active site
1429244005870	P2 response regulator binding domain; Region: P2; pfam07194
1429244005871	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1429244005872	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244005873	ATP binding site [chemical binding]; other site
1429244005874	Mg2+ binding site [ion binding]; other site
1429244005875	G-X-G motif; other site
1429244005876	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1429244005877	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1429244005878	putative CheA interaction surface; other site
1429244005879	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
1429244005880	CheC-like family; Region: CheC; pfam04509
1429244005881	CheC-like family; Region: CheC; pfam04509
1429244005882	Chemotaxis protein; stimulates methylation of MCP proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheD; COG1871
1429244005883	RNA polymerase sigma factor SigD; Validated; Region: PRK07670
1429244005884	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244005885	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1429244005886	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244005887	DNA binding residues [nucleotide binding]
1429244005888	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1429244005889	YceG-like family; Region: YceG; pfam02618
1429244005890	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1429244005891	rRNA interaction site [nucleotide binding]; other site
1429244005892	S8 interaction site; other site
1429244005893	putative laminin-1 binding site; other site
1429244005894	elongation factor Ts; Reviewed; Region: tsf; PRK12332
1429244005895	UBA/TS-N domain; Region: UBA; pfam00627
1429244005896	Elongation factor TS; Region: EF_TS; pfam00889
1429244005897	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1429244005898	putative nucleotide binding site [chemical binding]; other site
1429244005899	uridine monophosphate binding site [chemical binding]; other site
1429244005900	homohexameric interface [polypeptide binding]; other site
1429244005901	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1429244005902	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1429244005903	hinge region; other site
1429244005904	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1429244005905	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1429244005906	catalytic residue [active]
1429244005907	putative FPP diphosphate  binding site; other site
1429244005908	putative FPP binding hydrophobic cleft; other site
1429244005909	dimer interface [polypeptide binding]; other site
1429244005910	putative IPP diphosphate binding site; other site
1429244005911	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1429244005912	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1429244005913	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1429244005914	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1429244005915	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1429244005916	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1429244005917	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1429244005918	RIP metalloprotease RseP; Region: TIGR00054
1429244005919	active site
1429244005920	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1429244005921	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1429244005922	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1429244005923	putative substrate binding region [chemical binding]; other site
1429244005924	prolyl-tRNA synthetase; Provisional; Region: PRK08661
1429244005925	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
1429244005926	dimer interface [polypeptide binding]; other site
1429244005927	motif 1; other site
1429244005928	active site
1429244005929	motif 2; other site
1429244005930	motif 3; other site
1429244005931	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
1429244005932	anticodon binding site; other site
1429244005933	zinc-binding site [ion binding]; other site
1429244005934	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1429244005935	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
1429244005936	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
1429244005937	generic binding surface II; other site
1429244005938	generic binding surface I; other site
1429244005939	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1429244005940	active site
1429244005941	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1429244005942	active site
1429244005943	catalytic site [active]
1429244005944	substrate binding site [chemical binding]; other site
1429244005945	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
1429244005946	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1429244005947	Sm and related proteins; Region: Sm_like; cl00259
1429244005948	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1429244005949	putative oligomer interface [polypeptide binding]; other site
1429244005950	putative RNA binding site [nucleotide binding]; other site
1429244005951	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1429244005952	NusA N-terminal domain; Region: NusA_N; pfam08529
1429244005953	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1429244005954	RNA binding site [nucleotide binding]; other site
1429244005955	homodimer interface [polypeptide binding]; other site
1429244005956	NusA-like KH domain; Region: KH_5; pfam13184
1429244005957	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1429244005958	G-X-X-G motif; other site
1429244005959	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
1429244005960	putative RNA binding cleft [nucleotide binding]; other site
1429244005961	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
1429244005962	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1429244005963	translation initiation factor IF-2; Region: IF-2; TIGR00487
1429244005964	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1429244005965	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1429244005966	G1 box; other site
1429244005967	putative GEF interaction site [polypeptide binding]; other site
1429244005968	GTP/Mg2+ binding site [chemical binding]; other site
1429244005969	Switch I region; other site
1429244005970	G2 box; other site
1429244005971	G3 box; other site
1429244005972	Switch II region; other site
1429244005973	G4 box; other site
1429244005974	G5 box; other site
1429244005975	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1429244005976	Translation-initiation factor 2; Region: IF-2; pfam11987
1429244005977	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1429244005978	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1429244005979	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1429244005980	DHH family; Region: DHH; pfam01368
1429244005981	DHHA1 domain; Region: DHHA1; pfam02272
1429244005982	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
1429244005983	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1429244005984	RNA binding site [nucleotide binding]; other site
1429244005985	active site
1429244005986	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1429244005987	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1429244005988	active site
1429244005989	Riboflavin kinase; Region: Flavokinase; smart00904
1429244005990	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1429244005991	16S/18S rRNA binding site [nucleotide binding]; other site
1429244005992	S13e-L30e interaction site [polypeptide binding]; other site
1429244005993	25S rRNA binding site [nucleotide binding]; other site
1429244005994	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1429244005995	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1429244005996	RNase E interface [polypeptide binding]; other site
1429244005997	trimer interface [polypeptide binding]; other site
1429244005998	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1429244005999	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1429244006000	RNase E interface [polypeptide binding]; other site
1429244006001	trimer interface [polypeptide binding]; other site
1429244006002	active site
1429244006003	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1429244006004	putative nucleic acid binding region [nucleotide binding]; other site
1429244006005	G-X-X-G motif; other site
1429244006006	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1429244006007	RNA binding site [nucleotide binding]; other site
1429244006008	domain interface; other site
1429244006009	probable sporulation protein, polysaccharide deacetylase family; Region: spore_ylxY; TIGR02873
1429244006010	Putative catalytic NodB homology domain of uncharacterized protein YlxY from Bacillus subtilis and its bacterial homologs; Region: CE4_BsYlxY_like; cd10950
1429244006011	NodB motif; other site
1429244006012	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1429244006013	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1429244006014	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1429244006015	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1429244006016	trimer interface [polypeptide binding]; other site
1429244006017	active site
1429244006018	dipicolinate synthase subunit A; Reviewed; Region: PRK08306
1429244006019	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1429244006020	NAD binding site [chemical binding]; other site
1429244006021	dipicolinate synthase subunit B; Reviewed; Region: spoVFB; PRK08305
1429244006022	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1429244006023	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1429244006024	aspartate kinase I; Reviewed; Region: PRK08210
1429244006025	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1429244006026	nucleotide binding site [chemical binding]; other site
1429244006027	substrate binding site [chemical binding]; other site
1429244006028	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_1; cd04914
1429244006029	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1429244006030	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1429244006031	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1429244006032	dimer interface [polypeptide binding]; other site
1429244006033	active site
1429244006034	catalytic residue [active]
1429244006035	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1429244006036	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244006037	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1429244006038	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1429244006039	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1429244006040	active site
1429244006041	YlzJ-like protein; Region: YlzJ; pfam14035
1429244006042	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1429244006043	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1429244006044	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1429244006045	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1429244006046	spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869
1429244006047	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1429244006048	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1429244006049	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1429244006050	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1429244006051	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1429244006052	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1429244006053	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1429244006054	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1429244006055	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244006056	NAD(P) binding site [chemical binding]; other site
1429244006057	active site
1429244006058	Protein of unknown function (DUF3243); Region: DUF3243; pfam11588
1429244006059	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1429244006060	Protein of unknown function (DUF3388); Region: DUF3388; pfam11868
1429244006061	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1429244006062	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244006063	non-specific DNA binding site [nucleotide binding]; other site
1429244006064	salt bridge; other site
1429244006065	sequence-specific DNA binding site [nucleotide binding]; other site
1429244006066	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1429244006067	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1429244006068	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1429244006069	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1429244006070	competence damage-inducible protein A; Provisional; Region: PRK00549
1429244006071	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1429244006072	putative MPT binding site; other site
1429244006073	Competence-damaged protein; Region: CinA; pfam02464
1429244006074	recombinase A; Provisional; Region: recA; PRK09354
1429244006075	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1429244006076	hexamer interface [polypeptide binding]; other site
1429244006077	Walker A motif; other site
1429244006078	ATP binding site [chemical binding]; other site
1429244006079	Walker B motif; other site
1429244006080	RecX family; Region: RecX; cl00936
1429244006081	Domain of unknown function (DUF3552); Region: DUF3552; pfam12072
1429244006082	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1429244006083	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244006084	Zn2+ binding site [ion binding]; other site
1429244006085	Mg2+ binding site [ion binding]; other site
1429244006086	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
1429244006087	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1429244006088	putative active site [active]
1429244006089	metal binding site [ion binding]; metal-binding site
1429244006090	homodimer binding site [polypeptide binding]; other site
1429244006091	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
1429244006092	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1429244006093	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1429244006094	active site
1429244006095	dimer interface [polypeptide binding]; other site
1429244006096	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
1429244006097	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1429244006098	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1429244006099	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1429244006100	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14327
1429244006101	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1429244006102	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244006103	FeS/SAM binding site; other site
1429244006104	Protein of unknown function (DUF964); Region: DUF964; cl01483
1429244006105	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1429244006106	Thioesterase-like superfamily; Region: 4HBT_3; pfam13622
1429244006107	CoenzymeA binding site [chemical binding]; other site
1429244006108	subunit interaction site [polypeptide binding]; other site
1429244006109	PHB binding site; other site
1429244006110	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1429244006111	nudix motif; other site
1429244006112	Isochorismatase family; Region: Isochorismatase; pfam00857
1429244006113	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1429244006114	catalytic triad [active]
1429244006115	conserved cis-peptide bond; other site
1429244006116	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1429244006117	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1429244006118	active site
1429244006119	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1429244006120	MPT binding site; other site
1429244006121	trimer interface [polypeptide binding]; other site
1429244006122	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
1429244006123	dimerization interface [polypeptide binding]; other site
1429244006124	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
1429244006125	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1429244006126	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1429244006127	active site
1429244006128	HIGH motif; other site
1429244006129	KMSK motif region; other site
1429244006130	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1429244006131	tRNA binding surface [nucleotide binding]; other site
1429244006132	anticodon binding site; other site
1429244006133	S-layer homology domain; Region: SLH; pfam00395
1429244006134	PrcB C-terminal; Region: PrcB_C; pfam14343
1429244006135	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244006136	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244006137	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1429244006138	Walker A/P-loop; other site
1429244006139	ATP binding site [chemical binding]; other site
1429244006140	Q-loop/lid; other site
1429244006141	ABC transporter signature motif; other site
1429244006142	Walker B; other site
1429244006143	D-loop; other site
1429244006144	H-loop/switch region; other site
1429244006145	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244006146	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1429244006147	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244006148	Walker A/P-loop; other site
1429244006149	ATP binding site [chemical binding]; other site
1429244006150	Q-loop/lid; other site
1429244006151	ABC transporter signature motif; other site
1429244006152	Walker B; other site
1429244006153	D-loop; other site
1429244006154	H-loop/switch region; other site
1429244006155	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4841
1429244006156	Predicted membrane protein [Function unknown]; Region: COG2707
1429244006157	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
1429244006158	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
1429244006159	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244006160	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244006161	putative DNA binding site [nucleotide binding]; other site
1429244006162	dimerization interface [polypeptide binding]; other site
1429244006163	putative Zn2+ binding site [ion binding]; other site
1429244006164	Uncharacterized protein conserved in bacteria (DUF2087); Region: DUF2087; cl01589
1429244006165	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1429244006166	ribosome small subunit-dependent GTPase A; Region: TIGR00157
1429244006167	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1429244006168	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1429244006169	GTP/Mg2+ binding site [chemical binding]; other site
1429244006170	G4 box; other site
1429244006171	G5 box; other site
1429244006172	G1 box; other site
1429244006173	Switch I region; other site
1429244006174	G2 box; other site
1429244006175	G3 box; other site
1429244006176	Switch II region; other site
1429244006177	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1429244006178	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1429244006179	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
1429244006180	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1429244006181	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1429244006182	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1429244006183	Proteins of 100 residues with WXG; Region: WXG100; pfam06013
1429244006184	WXG100 family type VII secretion target; Region: WXG100_ESAT6; TIGR03930
1429244006185	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1429244006186	metal ion-dependent adhesion site (MIDAS); other site
1429244006187	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
1429244006188	active site
1429244006189	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1429244006190	classical (c) SDRs; Region: SDR_c; cd05233
1429244006191	NAD(P) binding site [chemical binding]; other site
1429244006192	active site
1429244006193	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1429244006194	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1429244006195	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
1429244006196	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1429244006197	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-C; cd09651
1429244006198	CRISPR/Cas system-associated protein Cas8c; Region: Cas8c_I-C; cd09757
1429244006199	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cl01465
1429244006200	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1429244006201	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
1429244006202	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
1429244006203	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
1429244006204	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1429244006205	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244006206	DNA-binding site [nucleotide binding]; DNA binding site
1429244006207	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244006208	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244006209	homodimer interface [polypeptide binding]; other site
1429244006210	catalytic residue [active]
1429244006211	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1429244006212	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1429244006213	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1429244006214	hypothetical protein; Validated; Region: PRK07682
1429244006215	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244006216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244006217	homodimer interface [polypeptide binding]; other site
1429244006218	catalytic residue [active]
1429244006219	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
1429244006220	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
1429244006221	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244006222	salt bridge; other site
1429244006223	non-specific DNA binding site [nucleotide binding]; other site
1429244006224	sequence-specific DNA binding site [nucleotide binding]; other site
1429244006225	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1429244006226	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1429244006227	Domain of unknown function (DUF1992); Region: DUF1992; cl08096
1429244006228	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1429244006229	active site
1429244006230	HIGH motif; other site
1429244006231	nucleotide binding site [chemical binding]; other site
1429244006232	active site
1429244006233	KMSKS motif; other site
1429244006234	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1429244006235	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244006236	ATP binding site [chemical binding]; other site
1429244006237	putative Mg++ binding site [ion binding]; other site
1429244006238	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244006239	nucleotide binding region [chemical binding]; other site
1429244006240	ATP-binding site [chemical binding]; other site
1429244006241	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
1429244006242	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1429244006243	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1429244006244	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1429244006245	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1429244006246	trimer interface [polypeptide binding]; other site
1429244006247	active site
1429244006248	substrate binding site [chemical binding]; other site
1429244006249	CoA binding site [chemical binding]; other site
1429244006250	Replication terminator protein; Region: RTP; pfam02334
1429244006251	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244006252	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244006253	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244006254	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1429244006255	DivIVA protein; Region: DivIVA; pfam05103
1429244006256	DivIVA domain; Region: DivI1A_domain; TIGR03544
1429244006257	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1429244006258	Rrf2 family protein; Region: rrf2_super; TIGR00738
1429244006259	Transcriptional regulator; Region: Rrf2; pfam02082
1429244006260	Transcriptional regulator; Region: Rrf2; cl17282
1429244006261	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1429244006262	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1429244006263	active site
1429244006264	metal binding site [ion binding]; metal-binding site
1429244006265	homotetramer interface [polypeptide binding]; other site
1429244006266	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
1429244006267	dimer interface [polypeptide binding]; other site
1429244006268	[2Fe-2S] cluster binding site [ion binding]; other site
1429244006269	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
1429244006270	dimer interface [polypeptide binding]; other site
1429244006271	FMN binding site [chemical binding]; other site
1429244006272	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1429244006273	cobyric acid synthase; Provisional; Region: PRK00784
1429244006274	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244006275	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244006276	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1429244006277	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1429244006278	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1429244006279	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
1429244006280	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1429244006281	Uncharacterized conserved protein [Function unknown]; Region: COG2135
1429244006282	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244006283	benzoate transport; Region: 2A0115; TIGR00895
1429244006284	putative substrate translocation pore; other site
1429244006285	OsmC-like protein; Region: OsmC; cl00767
1429244006286	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1429244006287	azoreductase; Provisional; Region: PRK13556
1429244006288	glutamate racemase; Provisional; Region: PRK00865
1429244006289	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244006290	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; cl17810
1429244006291	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
1429244006292	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1429244006293	active site
1429244006294	metal binding site [ion binding]; metal-binding site
1429244006295	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1429244006296	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1429244006297	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
1429244006298	active site
1429244006299	catalytic residues [active]
1429244006300	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
1429244006301	acetolactate synthase; Reviewed; Region: PRK08617
1429244006302	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1429244006303	PYR/PP interface [polypeptide binding]; other site
1429244006304	dimer interface [polypeptide binding]; other site
1429244006305	TPP binding site [chemical binding]; other site
1429244006306	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1429244006307	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1429244006308	TPP-binding site [chemical binding]; other site
1429244006309	dimer interface [polypeptide binding]; other site
1429244006310	Glucuronate isomerase; Region: UxaC; pfam02614
1429244006311	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1429244006312	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1429244006313	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244006314	putative substrate translocation pore; other site
1429244006315	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244006316	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244006317	DNA binding site [nucleotide binding]
1429244006318	domain linker motif; other site
1429244006319	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244006320	dimerization interface [polypeptide binding]; other site
1429244006321	ligand binding site [chemical binding]; other site
1429244006322	pyruvate dehydrogenase; Provisional; Region: PRK09124
1429244006323	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1429244006324	PYR/PP interface [polypeptide binding]; other site
1429244006325	dimer interface [polypeptide binding]; other site
1429244006326	tetramer interface [polypeptide binding]; other site
1429244006327	TPP binding site [chemical binding]; other site
1429244006328	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1429244006329	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1429244006330	TPP-binding site [chemical binding]; other site
1429244006331	altronate oxidoreductase; Provisional; Region: PRK03643
1429244006332	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1429244006333	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1429244006334	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1429244006335	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1429244006336	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1429244006337	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244006338	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244006339	dimer interface [polypeptide binding]; other site
1429244006340	conserved gate region; other site
1429244006341	ABC-ATPase subunit interface; other site
1429244006342	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244006343	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244006344	dimer interface [polypeptide binding]; other site
1429244006345	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1429244006346	ABC-ATPase subunit interface; other site
1429244006347	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244006348	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244006349	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244006350	dimerization interface [polypeptide binding]; other site
1429244006351	Histidine kinase; Region: His_kinase; pfam06580
1429244006352	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244006353	ATP binding site [chemical binding]; other site
1429244006354	Mg2+ binding site [ion binding]; other site
1429244006355	G-X-G motif; other site
1429244006356	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244006357	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244006358	active site
1429244006359	phosphorylation site [posttranslational modification]
1429244006360	intermolecular recognition site; other site
1429244006361	dimerization interface [polypeptide binding]; other site
1429244006362	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244006363	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244006364	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244006365	Protein of unknown function (DUF3891); Region: DUF3891; pfam13030
1429244006366	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
1429244006367	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1429244006368	ligand binding site; other site
1429244006369	oligomer interface; other site
1429244006370	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1429244006371	dimer interface [polypeptide binding]; other site
1429244006372	N-terminal domain interface [polypeptide binding]; other site
1429244006373	sulfate 1 binding site; other site
1429244006374	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
1429244006375	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1429244006376	ligand binding site; other site
1429244006377	oligomer interface; other site
1429244006378	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1429244006379	dimer interface [polypeptide binding]; other site
1429244006380	N-terminal domain interface [polypeptide binding]; other site
1429244006381	sulfate 1 binding site; other site
1429244006382	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1429244006383	homodimer interface [polypeptide binding]; other site
1429244006384	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
1429244006385	active site pocket [active]
1429244006386	Uncharacterized protein conserved in bacteria (DUF2062); Region: DUF2062; pfam09835
1429244006387	Predicted membrane protein [Function unknown]; Region: COG1511
1429244006388	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1429244006389	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1429244006390	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244006391	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244006392	active site
1429244006393	catalytic tetrad [active]
1429244006394	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1429244006395	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1429244006396	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1429244006397	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1429244006398	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244006399	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244006400	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244006401	dimerization interface [polypeptide binding]; other site
1429244006402	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1429244006403	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244006404	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
1429244006405	Walker A/P-loop; other site
1429244006406	ATP binding site [chemical binding]; other site
1429244006407	Q-loop/lid; other site
1429244006408	ABC transporter signature motif; other site
1429244006409	Walker B; other site
1429244006410	D-loop; other site
1429244006411	H-loop/switch region; other site
1429244006412	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1429244006413	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1429244006414	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244006415	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244006416	active site
1429244006417	phosphorylation site [posttranslational modification]
1429244006418	intermolecular recognition site; other site
1429244006419	dimerization interface [polypeptide binding]; other site
1429244006420	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244006421	DNA binding site [nucleotide binding]
1429244006422	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244006423	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244006424	dimer interface [polypeptide binding]; other site
1429244006425	phosphorylation site [posttranslational modification]
1429244006426	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244006427	ATP binding site [chemical binding]; other site
1429244006428	Mg2+ binding site [ion binding]; other site
1429244006429	G-X-G motif; other site
1429244006430	Predicted membrane protein [Function unknown]; Region: COG2323
1429244006431	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1429244006432	catalytic residues [active]
1429244006433	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1429244006434	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1429244006435	active site
1429244006436	non-prolyl cis peptide bond; other site
1429244006437	FMN reductase, SsuE family; Region: FMN_reduc_SsuE; TIGR03567
1429244006438	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244006439	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244006440	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244006441	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244006442	dimerization interface [polypeptide binding]; other site
1429244006443	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244006444	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244006445	substrate binding pocket [chemical binding]; other site
1429244006446	membrane-bound complex binding site; other site
1429244006447	hinge residues; other site
1429244006448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244006449	dimer interface [polypeptide binding]; other site
1429244006450	conserved gate region; other site
1429244006451	putative PBP binding loops; other site
1429244006452	ABC-ATPase subunit interface; other site
1429244006453	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1429244006454	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244006455	dimer interface [polypeptide binding]; other site
1429244006456	conserved gate region; other site
1429244006457	putative PBP binding loops; other site
1429244006458	ABC-ATPase subunit interface; other site
1429244006459	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244006460	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244006461	Walker A/P-loop; other site
1429244006462	ATP binding site [chemical binding]; other site
1429244006463	Q-loop/lid; other site
1429244006464	ABC transporter signature motif; other site
1429244006465	Walker B; other site
1429244006466	D-loop; other site
1429244006467	H-loop/switch region; other site
1429244006468	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1429244006469	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1429244006470	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
1429244006471	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244006472	metal binding site [ion binding]; metal-binding site
1429244006473	dimer interface [polypeptide binding]; other site
1429244006474	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1429244006475	CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain; Region: CRD_FZ; cl02447
1429244006476	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244006477	dimerization interface [polypeptide binding]; other site
1429244006478	putative DNA binding site [nucleotide binding]; other site
1429244006479	putative Zn2+ binding site [ion binding]; other site
1429244006480	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244006481	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1429244006482	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244006483	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244006484	dimer interface [polypeptide binding]; other site
1429244006485	conserved gate region; other site
1429244006486	putative PBP binding loops; other site
1429244006487	ABC-ATPase subunit interface; other site
1429244006488	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244006489	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244006490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244006491	dimer interface [polypeptide binding]; other site
1429244006492	conserved gate region; other site
1429244006493	putative PBP binding loops; other site
1429244006494	ABC-ATPase subunit interface; other site
1429244006495	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244006496	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244006497	Walker A/P-loop; other site
1429244006498	ATP binding site [chemical binding]; other site
1429244006499	Q-loop/lid; other site
1429244006500	ABC transporter signature motif; other site
1429244006501	Walker B; other site
1429244006502	D-loop; other site
1429244006503	H-loop/switch region; other site
1429244006504	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244006505	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244006506	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244006507	Walker A/P-loop; other site
1429244006508	ATP binding site [chemical binding]; other site
1429244006509	Q-loop/lid; other site
1429244006510	ABC transporter signature motif; other site
1429244006511	Walker B; other site
1429244006512	D-loop; other site
1429244006513	H-loop/switch region; other site
1429244006514	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244006515	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1429244006516	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1429244006517	Cation efflux family; Region: Cation_efflux; pfam01545
1429244006518	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
1429244006519	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1429244006520	RDD family; Region: RDD; pfam06271
1429244006521	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244006522	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244006523	intersubunit interface [polypeptide binding]; other site
1429244006524	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1429244006525	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1429244006526	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1429244006527	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1429244006528	dimer interface [polypeptide binding]; other site
1429244006529	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244006530	catalytic residue [active]
1429244006531	cystathionine beta-lyase; Provisional; Region: PRK07671
1429244006532	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1429244006533	homodimer interface [polypeptide binding]; other site
1429244006534	substrate-cofactor binding pocket; other site
1429244006535	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244006536	catalytic residue [active]
1429244006537	Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: LpqC; COG3509
1429244006538	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1429244006539	classical (c) SDRs; Region: SDR_c; cd05233
1429244006540	NAD(P) binding site [chemical binding]; other site
1429244006541	active site
1429244006542	Nucleolar RNA-binding protein, Nop10p family; Region: Nop10p; cl00977
1429244006543	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1429244006544	metal ion-dependent adhesion site (MIDAS); other site
1429244006545	Tubulin like; Region: Tubulin_2; pfam13809
1429244006546	Tubulin like; Region: Tubulin_2; pfam13809
1429244006547	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1429244006548	metal ion-dependent adhesion site (MIDAS); other site
1429244006549	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1429244006550	MarR family; Region: MarR_2; pfam12802
1429244006551	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244006552	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244006553	putative substrate translocation pore; other site
1429244006554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244006555	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1429244006556	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1429244006557	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1429244006558	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1429244006559	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1429244006560	TIGR03943 family protein; Region: TIGR03943
1429244006561	Predicted permeases [General function prediction only]; Region: COG0701
1429244006562	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1429244006563	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1429244006564	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1429244006565	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244006566	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244006567	ABC-ATPase subunit  interface; other site
1429244006568	dimer interface [polypeptide binding]; other site
1429244006569	putative PBP binding regions; other site
1429244006570	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244006571	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244006572	Walker A/P-loop; other site
1429244006573	ATP binding site [chemical binding]; other site
1429244006574	Q-loop/lid; other site
1429244006575	ABC transporter signature motif; other site
1429244006576	Walker B; other site
1429244006577	D-loop; other site
1429244006578	H-loop/switch region; other site
1429244006579	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
1429244006580	Metal binding protein TroA_a.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148
1429244006581	putative ligand binding residues [chemical binding]; other site
1429244006582	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1429244006583	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244006584	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1429244006585	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244006586	ABC-ATPase subunit  interface; other site
1429244006587	dimer interface [polypeptide binding]; other site
1429244006588	putative PBP binding regions; other site
1429244006589	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1429244006590	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
1429244006591	metal binding site [ion binding]; metal-binding site
1429244006592	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244006593	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244006594	active site
1429244006595	phosphorylation site [posttranslational modification]
1429244006596	intermolecular recognition site; other site
1429244006597	dimerization interface [polypeptide binding]; other site
1429244006598	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244006599	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1429244006600	WYL domain; Region: WYL; cl14852
1429244006601	YolD-like protein; Region: YolD; pfam08863
1429244006602	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1429244006603	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244006604	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244006605	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244006606	NAD(P) binding site [chemical binding]; other site
1429244006607	active site
1429244006608	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244006609	Streptomycin adenylyltransferase; Region: Adenyl_transf; pfam04439
1429244006610	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244006611	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244006612	S-adenosylmethionine binding site [chemical binding]; other site
1429244006613	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1429244006614	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1429244006615	dimerization interface [polypeptide binding]; other site
1429244006616	domain crossover interface; other site
1429244006617	redox-dependent activation switch; other site
1429244006618	Predicted transcriptional regulator [Transcription]; Region: COG1959
1429244006619	Transcriptional regulator; Region: Rrf2; pfam02082
1429244006620	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1429244006621	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1429244006622	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1429244006623	short chain dehydrogenase; Validated; Region: PRK08324
1429244006624	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
1429244006625	active site
1429244006626	intersubunit interface [polypeptide binding]; other site
1429244006627	Zn2+ binding site [ion binding]; other site
1429244006628	rhamnulose-1-phosphate aldolase/alcohol dehydrogenase, classical (c) SDRs; Region: R1PA_ADH_SDR_c; cd08943
1429244006629	putative NAD(P) binding site [chemical binding]; other site
1429244006630	active site
1429244006631	L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype; Region: L_rham_iso_rhiz; TIGR02629
1429244006632	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1429244006633	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1429244006634	N- and C-terminal domain interface [polypeptide binding]; other site
1429244006635	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
1429244006636	active site
1429244006637	putative catalytic site [active]
1429244006638	metal binding site [ion binding]; metal-binding site
1429244006639	ATP binding site [chemical binding]; other site
1429244006640	carbohydrate binding site [chemical binding]; other site
1429244006641	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1429244006642	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1429244006643	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1429244006644	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
1429244006645	Cysteine-rich domain; Region: CCG; pfam02754
1429244006646	Cysteine-rich domain; Region: CCG; pfam02754
1429244006647	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
1429244006648	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1429244006649	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1429244006650	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1429244006651	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1429244006652	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244006653	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244006654	DNA binding site [nucleotide binding]
1429244006655	domain linker motif; other site
1429244006656	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1429244006657	putative dimerization interface [polypeptide binding]; other site
1429244006658	putative ligand binding site [chemical binding]; other site
1429244006659	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244006660	beta-galactosidase; Region: BGL; TIGR03356
1429244006661	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1429244006662	EamA-like transporter family; Region: EamA; pfam00892
1429244006663	EamA-like transporter family; Region: EamA; pfam00892
1429244006664	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244006665	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244006666	PRD domain; Region: PRD; pfam00874
1429244006667	PRD domain; Region: PRD; pfam00874
1429244006668	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244006669	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244006670	active site turn [active]
1429244006671	phosphorylation site [posttranslational modification]
1429244006672	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244006673	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1429244006674	HPr interaction site; other site
1429244006675	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244006676	active site
1429244006677	phosphorylation site [posttranslational modification]
1429244006678	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244006679	beta-galactosidase; Region: BGL; TIGR03356
1429244006680	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1429244006681	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244006682	dimerization interface [polypeptide binding]; other site
1429244006683	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244006684	dimer interface [polypeptide binding]; other site
1429244006685	phosphorylation site [posttranslational modification]
1429244006686	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244006687	ATP binding site [chemical binding]; other site
1429244006688	Mg2+ binding site [ion binding]; other site
1429244006689	G-X-G motif; other site
1429244006690	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244006691	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244006692	active site
1429244006693	phosphorylation site [posttranslational modification]
1429244006694	intermolecular recognition site; other site
1429244006695	dimerization interface [polypeptide binding]; other site
1429244006696	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244006697	DNA binding site [nucleotide binding]
1429244006698	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1429244006699	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1429244006700	CHRD domain; Region: CHRD; pfam07452
1429244006701	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1429244006702	active site
1429244006703	catalytic triad [active]
1429244006704	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1429244006705	DNA binding site [nucleotide binding]
1429244006706	active site
1429244006707	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1429244006708	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244006709	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1429244006710	Walker A/P-loop; other site
1429244006711	ATP binding site [chemical binding]; other site
1429244006712	Q-loop/lid; other site
1429244006713	ABC transporter signature motif; other site
1429244006714	Walker B; other site
1429244006715	D-loop; other site
1429244006716	H-loop/switch region; other site
1429244006717	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1429244006718	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1429244006719	FtsX-like permease family; Region: FtsX; pfam02687
1429244006720	HTH domain; Region: HTH_11; pfam08279
1429244006721	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1429244006722	FOG: CBS domain [General function prediction only]; Region: COG0517
1429244006723	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
1429244006724	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1429244006725	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1429244006726	putative active site [active]
1429244006727	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1429244006728	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244006729	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244006730	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244006731	Walker A/P-loop; other site
1429244006732	ATP binding site [chemical binding]; other site
1429244006733	Q-loop/lid; other site
1429244006734	ABC transporter signature motif; other site
1429244006735	Walker B; other site
1429244006736	D-loop; other site
1429244006737	H-loop/switch region; other site
1429244006738	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244006739	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244006740	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
1429244006741	Walker A/P-loop; other site
1429244006742	ATP binding site [chemical binding]; other site
1429244006743	Q-loop/lid; other site
1429244006744	ABC transporter signature motif; other site
1429244006745	Walker B; other site
1429244006746	D-loop; other site
1429244006747	H-loop/switch region; other site
1429244006748	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244006749	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1429244006750	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1429244006751	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1429244006752	acyl-activating enzyme (AAE) consensus motif; other site
1429244006753	AMP binding site [chemical binding]; other site
1429244006754	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244006755	Condensation domain; Region: Condensation; pfam00668
1429244006756	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244006757	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244006758	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1429244006759	acyl-activating enzyme (AAE) consensus motif; other site
1429244006760	AMP binding site [chemical binding]; other site
1429244006761	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244006762	Condensation domain; Region: Condensation; pfam00668
1429244006763	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244006764	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1429244006765	Condensation domain; Region: Condensation; pfam00668
1429244006766	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244006767	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1429244006768	acyl-activating enzyme (AAE) consensus motif; other site
1429244006769	AMP binding site [chemical binding]; other site
1429244006770	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244006771	Thioesterase domain; Region: Thioesterase; pfam00975
1429244006772	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244006773	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244006774	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
1429244006775	generic binding surface II; other site
1429244006776	generic binding surface I; other site
1429244006777	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1429244006778	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1429244006779	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1429244006780	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1429244006781	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1429244006782	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
1429244006783	HTH domain; Region: HTH_11; pfam08279
1429244006784	3H domain; Region: 3H; pfam02829
1429244006785	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244006786	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1429244006787	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244006788	catalytic residue [active]
1429244006789	quinolinate synthetase; Provisional; Region: PRK09375
1429244006790	FOG: WD40-like repeat [Function unknown]; Region: COG1520
1429244006791	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
1429244006792	PQQ-like domain; Region: PQQ_2; pfam13360
1429244006793	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1429244006794	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1429244006795	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1429244006796	active site
1429244006797	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1429244006798	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1429244006799	active site
1429244006800	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244006801	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244006802	active site
1429244006803	phosphorylation site [posttranslational modification]
1429244006804	intermolecular recognition site; other site
1429244006805	dimerization interface [polypeptide binding]; other site
1429244006806	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244006807	DNA binding site [nucleotide binding]
1429244006808	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244006809	HAMP domain; Region: HAMP; pfam00672
1429244006810	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244006811	dimer interface [polypeptide binding]; other site
1429244006812	phosphorylation site [posttranslational modification]
1429244006813	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244006814	ATP binding site [chemical binding]; other site
1429244006815	Mg2+ binding site [ion binding]; other site
1429244006816	G-X-G motif; other site
1429244006817	NlpC/P60 family; Region: NLPC_P60; pfam00877
1429244006818	This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802
1429244006819	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
1429244006820	putative ADP-binding pocket [chemical binding]; other site
1429244006821	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1429244006822	Predicted deacylase [General function prediction only]; Region: COG3608
1429244006823	active site
1429244006824	Zn binding site [ion binding]; other site
1429244006825	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244006826	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1429244006827	active site
1429244006828	Cupin domain; Region: Cupin_2; cl17218
1429244006829	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244006830	DinB superfamily; Region: DinB_2; pfam12867
1429244006831	Protein of unknown function (DUF1572); Region: DUF1572; pfam07609
1429244006832	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
1429244006833	CGNR zinc finger; Region: zf-CGNR; pfam11706
1429244006834	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244006835	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244006836	Walker A/P-loop; other site
1429244006837	ATP binding site [chemical binding]; other site
1429244006838	Q-loop/lid; other site
1429244006839	ABC transporter signature motif; other site
1429244006840	Walker B; other site
1429244006841	D-loop; other site
1429244006842	H-loop/switch region; other site
1429244006843	Predicted permeases [General function prediction only]; Region: COG0679
1429244006844	hypothetical protein; Validated; Region: PRK01415
1429244006845	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1429244006846	active site residue [active]
1429244006847	alpha-galactosidase; Region: PLN02808; cl17638
1429244006848	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1429244006849	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1429244006850	substrate binding site [chemical binding]; other site
1429244006851	ATP binding site [chemical binding]; other site
1429244006852	AAA domain; Region: AAA_17; pfam13207
1429244006853	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1429244006854	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1429244006855	dimer interface [polypeptide binding]; other site
1429244006856	motif 1; other site
1429244006857	active site
1429244006858	motif 2; other site
1429244006859	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1429244006860	putative deacylase active site [active]
1429244006861	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1429244006862	active site
1429244006863	motif 3; other site
1429244006864	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1429244006865	anticodon binding site; other site
1429244006866	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1429244006867	hypothetical protein; Provisional; Region: PRK12378
1429244006868	bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404
1429244006869	Cupin; Region: Cupin_1; smart00835
1429244006870	Cupin; Region: Cupin_1; smart00835
1429244006871	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1429244006872	putative deacylase active site [active]
1429244006873	hypothetical protein; Provisional; Region: PRK06771
1429244006874	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1429244006875	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244006876	nucleotide binding site [chemical binding]; other site
1429244006877	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
1429244006878	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244006879	beta-galactosidase; Region: BGL; TIGR03356
1429244006880	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
1429244006881	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244006882	putative metal binding site [ion binding]; other site
1429244006883	maltose O-acetyltransferase; Provisional; Region: PRK10092
1429244006884	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1429244006885	active site
1429244006886	substrate binding site [chemical binding]; other site
1429244006887	trimer interface [polypeptide binding]; other site
1429244006888	CoA binding site [chemical binding]; other site
1429244006889	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1429244006890	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1429244006891	active site
1429244006892	metal binding site [ion binding]; metal-binding site
1429244006893	homotetramer interface [polypeptide binding]; other site
1429244006894	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
1429244006895	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1429244006896	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1429244006897	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
1429244006898	putative active site; other site
1429244006899	catalytic triad [active]
1429244006900	putative dimer interface [polypeptide binding]; other site
1429244006901	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244006902	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1429244006903	active site
1429244006904	FMN binding site [chemical binding]; other site
1429244006905	substrate binding site [chemical binding]; other site
1429244006906	putative catalytic residue [active]
1429244006907	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1429244006908	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244006909	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244006910	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1429244006911	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244006912	active site
1429244006913	substrate binding site [chemical binding]; other site
1429244006914	ATP binding site [chemical binding]; other site
1429244006915	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244006916	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244006917	intersubunit interface [polypeptide binding]; other site
1429244006918	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244006919	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244006920	ABC-ATPase subunit  interface; other site
1429244006921	dimer interface [polypeptide binding]; other site
1429244006922	putative PBP binding regions; other site
1429244006923	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244006924	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244006925	ABC-ATPase subunit  interface; other site
1429244006926	dimer interface [polypeptide binding]; other site
1429244006927	putative PBP binding regions; other site
1429244006928	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1429244006929	dimer interface [polypeptide binding]; other site
1429244006930	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244006931	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1429244006932	catalytic core [active]
1429244006933	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1429244006934	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244006935	RNA binding surface [nucleotide binding]; other site
1429244006936	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1429244006937	probable active site [active]
1429244006938	Spore germination protein; Region: Spore_permease; cl17796
1429244006939	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244006940	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244006941	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244006942	LysE type translocator; Region: LysE; cl00565
1429244006943	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244006944	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244006945	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244006946	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1429244006947	oligomerization interface [polypeptide binding]; other site
1429244006948	active site
1429244006949	metal binding site [ion binding]; metal-binding site
1429244006950	TAP-like protein; Region: Abhydrolase_4; pfam08386
1429244006951	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1429244006952	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244006953	NAD(P) binding site [chemical binding]; other site
1429244006954	active site
1429244006955	Helix-Turn-Helix DNA binding domain of the BltR transcription regulator; Region: HTH_BltR; cd04782
1429244006956	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244006957	DNA binding residues [nucleotide binding]
1429244006958	dimer interface [polypeptide binding]; other site
1429244006959	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1429244006960	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244006961	MarR family; Region: MarR_2; pfam12802
1429244006962	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1429244006963	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1429244006964	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244006965	Protein of unknown function (DUF3782); Region: DUF3782; pfam12644
1429244006966	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244006967	S-adenosylmethionine binding site [chemical binding]; other site
1429244006968	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244006969	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244006970	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244006971	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244006972	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244006973	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244006974	intersubunit interface [polypeptide binding]; other site
1429244006975	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1429244006976	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244006977	siderophore binding site; other site
1429244006978	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244006979	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244006980	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1429244006981	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1429244006982	oligomer interface [polypeptide binding]; other site
1429244006983	active site residues [active]
1429244006984	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1429244006985	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244006986	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244006987	DNA binding residues [nucleotide binding]
1429244006988	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1429244006989	Domain of unknown function (DUF4303); Region: DUF4303; pfam14136
1429244006990	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1429244006991	active site
1429244006992	Mor transcription activator family; Region: Mor; cl02360
1429244006993	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1429244006994	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
1429244006995	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
1429244006996	catalytic residues [active]
1429244006997	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1429244006998	Cache domain; Region: Cache_1; pfam02743
1429244006999	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244007000	dimerization interface [polypeptide binding]; other site
1429244007001	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244007002	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244007003	dimer interface [polypeptide binding]; other site
1429244007004	putative CheW interface [polypeptide binding]; other site
1429244007005	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244007006	dimer interface [polypeptide binding]; other site
1429244007007	phosphorylation site [posttranslational modification]
1429244007008	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007009	ATP binding site [chemical binding]; other site
1429244007010	Mg2+ binding site [ion binding]; other site
1429244007011	G-X-G motif; other site
1429244007012	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007013	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244007014	active site
1429244007015	phosphorylation site [posttranslational modification]
1429244007016	dimerization interface [polypeptide binding]; other site
1429244007017	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1429244007018	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007019	active site
1429244007020	phosphorylation site [posttranslational modification]
1429244007021	intermolecular recognition site; other site
1429244007022	dimerization interface [polypeptide binding]; other site
1429244007023	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244007024	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007025	active site
1429244007026	phosphorylation site [posttranslational modification]
1429244007027	intermolecular recognition site; other site
1429244007028	dimerization interface [polypeptide binding]; other site
1429244007029	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244007030	DNA binding site [nucleotide binding]
1429244007031	diaminobutyrate--2-oxoglutarate aminotransferase; Validated; Region: PRK09264
1429244007032	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1429244007033	inhibitor-cofactor binding pocket; inhibition site
1429244007034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244007035	catalytic residue [active]
1429244007036	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1429244007037	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244007038	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244007039	metal binding site [ion binding]; metal-binding site
1429244007040	active site
1429244007041	I-site; other site
1429244007042	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1429244007043	N-terminal domain of cellobiose phosphorylase (CBP) and similar proteins; Region: GH94N_CBP_like; cd11754
1429244007044	catalytic domain interface [polypeptide binding]; other site
1429244007045	homodimer interface [polypeptide binding]; other site
1429244007046	putative active site [active]
1429244007047	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1429244007048	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1429244007049	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
1429244007050	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1429244007051	Ferritin-like domain; Region: Ferritin; pfam00210
1429244007052	ferroxidase diiron center [ion binding]; other site
1429244007053	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1429244007054	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244007055	Coenzyme A binding pocket [chemical binding]; other site
1429244007056	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
1429244007057	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1429244007058	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1429244007059	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1429244007060	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244007061	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
1429244007062	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
1429244007063	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1429244007064	acyl-activating enzyme (AAE) consensus motif; other site
1429244007065	AMP binding site [chemical binding]; other site
1429244007066	active site
1429244007067	CoA binding site [chemical binding]; other site
1429244007068	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1429244007069	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1429244007070	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244007071	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244007072	Protein of unknown function with HXXEE motif; Region: HXXEE; pfam13787
1429244007073	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244007074	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244007075	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1429244007076	CPxP  motif; other site
1429244007077	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1429244007078	active site residue [active]
1429244007079	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
1429244007080	Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155
1429244007081	putative homodimer interface [polypeptide binding]; other site
1429244007082	putative homotetramer interface [polypeptide binding]; other site
1429244007083	putative metal binding site [ion binding]; other site
1429244007084	putative homodimer-homodimer interface [polypeptide binding]; other site
1429244007085	putative allosteric switch controlling residues; other site
1429244007086	Predicted membrane protein [Function unknown]; Region: COG2323
1429244007087	Spore germination protein; Region: Spore_permease; cl17796
1429244007088	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244007089	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244007090	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244007091	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1429244007092	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1429244007093	homodimer interface [polypeptide binding]; other site
1429244007094	substrate-cofactor binding pocket; other site
1429244007095	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244007096	catalytic residue [active]
1429244007097	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244007098	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1429244007099	HTH domain; Region: HTH_11; pfam08279
1429244007100	Mga helix-turn-helix domain; Region: Mga; pfam05043
1429244007101	PRD domain; Region: PRD; pfam00874
1429244007102	PRD domain; Region: PRD; pfam00874
1429244007103	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1429244007104	active site
1429244007105	P-loop; other site
1429244007106	phosphorylation site [posttranslational modification]
1429244007107	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244007108	active site
1429244007109	phosphorylation site [posttranslational modification]
1429244007110	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1429244007111	active site
1429244007112	P-loop; other site
1429244007113	phosphorylation site [posttranslational modification]
1429244007114	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1429244007115	active site
1429244007116	methionine cluster; other site
1429244007117	phosphorylation site [posttranslational modification]
1429244007118	metal binding site [ion binding]; metal-binding site
1429244007119	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1429244007120	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1429244007121	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1429244007122	beta-galactosidase; Region: BGL; TIGR03356
1429244007123	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1429244007124	Melibiase; Region: Melibiase; pfam02065
1429244007125	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244007126	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244007127	DNA binding site [nucleotide binding]
1429244007128	domain linker motif; other site
1429244007129	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1429244007130	putative dimerization interface [polypeptide binding]; other site
1429244007131	putative ligand binding site [chemical binding]; other site
1429244007132	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244007133	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244007134	dimerization interface [polypeptide binding]; other site
1429244007135	Histidine kinase; Region: His_kinase; pfam06580
1429244007136	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007137	ATP binding site [chemical binding]; other site
1429244007138	Mg2+ binding site [ion binding]; other site
1429244007139	G-X-G motif; other site
1429244007140	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244007141	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007142	active site
1429244007143	phosphorylation site [posttranslational modification]
1429244007144	intermolecular recognition site; other site
1429244007145	dimerization interface [polypeptide binding]; other site
1429244007146	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007147	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007148	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244007149	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244007150	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007151	dimer interface [polypeptide binding]; other site
1429244007152	conserved gate region; other site
1429244007153	putative PBP binding loops; other site
1429244007154	ABC-ATPase subunit interface; other site
1429244007155	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244007156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007157	dimer interface [polypeptide binding]; other site
1429244007158	conserved gate region; other site
1429244007159	putative PBP binding loops; other site
1429244007160	ABC-ATPase subunit interface; other site
1429244007161	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244007162	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007163	active site
1429244007164	phosphorylation site [posttranslational modification]
1429244007165	intermolecular recognition site; other site
1429244007166	dimerization interface [polypeptide binding]; other site
1429244007167	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244007168	DNA binding site [nucleotide binding]
1429244007169	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244007170	His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388
1429244007171	dimer interface [polypeptide binding]; other site
1429244007172	phosphorylation site [posttranslational modification]
1429244007173	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007174	ATP binding site [chemical binding]; other site
1429244007175	Mg2+ binding site [ion binding]; other site
1429244007176	G-X-G motif; other site
1429244007177	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244007178	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1429244007179	Walker A/P-loop; other site
1429244007180	ATP binding site [chemical binding]; other site
1429244007181	Q-loop/lid; other site
1429244007182	ABC transporter signature motif; other site
1429244007183	Walker B; other site
1429244007184	D-loop; other site
1429244007185	H-loop/switch region; other site
1429244007186	FtsX-like permease family; Region: FtsX; pfam02687
1429244007187	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1429244007188	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1429244007189	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1429244007190	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244007191	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244007192	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244007193	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1429244007194	Walker A/P-loop; other site
1429244007195	ATP binding site [chemical binding]; other site
1429244007196	Q-loop/lid; other site
1429244007197	ABC transporter signature motif; other site
1429244007198	Walker B; other site
1429244007199	D-loop; other site
1429244007200	H-loop/switch region; other site
1429244007201	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1429244007202	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1429244007203	FtsX-like permease family; Region: FtsX; pfam02687
1429244007204	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1429244007205	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1429244007206	NodB motif; other site
1429244007207	active site
1429244007208	catalytic site [active]
1429244007209	Zn binding site [ion binding]; other site
1429244007210	RNA polymerase sigma factor SigX; Provisional; Region: PRK09639
1429244007211	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244007212	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244007213	DNA binding residues [nucleotide binding]
1429244007214	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1429244007215	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac2_AmyA; cd11316
1429244007216	Ca binding site [ion binding]; other site
1429244007217	active site
1429244007218	catalytic site [active]
1429244007219	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1429244007220	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1429244007221	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1429244007222	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244007223	motif II; other site
1429244007224	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1429244007225	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1429244007226	NAD(P) binding site [chemical binding]; other site
1429244007227	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1429244007228	4-aminobutyrate aminotransferase; Provisional; Region: PRK05769
1429244007229	inhibitor-cofactor binding pocket; inhibition site
1429244007230	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244007231	catalytic residue [active]
1429244007232	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244007233	putative substrate translocation pore; other site
1429244007234	Cupin domain; Region: Cupin_2; pfam07883
1429244007235	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007236	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007237	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007238	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244007239	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244007240	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244007241	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
1429244007242	Helix-turn-helix domain; Region: HTH_18; pfam12833
1429244007243	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007244	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1429244007245	classical (c) SDRs; Region: SDR_c; cd05233
1429244007246	NAD(P) binding site [chemical binding]; other site
1429244007247	active site
1429244007248	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1429244007249	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244007250	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244007251	Coenzyme A binding pocket [chemical binding]; other site
1429244007252	S-layer homology domain; Region: SLH; pfam00395
1429244007253	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244007254	putative substrate translocation pore; other site
1429244007255	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244007256	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244007257	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244007258	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1429244007259	dimerization interface [polypeptide binding]; other site
1429244007260	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244007261	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007262	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007263	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007264	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1429244007265	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1429244007266	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1429244007267	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1429244007268	Predicted transcriptional regulator [Transcription]; Region: COG4189
1429244007269	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244007270	putative DNA binding site [nucleotide binding]; other site
1429244007271	dimerization interface [polypeptide binding]; other site
1429244007272	putative Zn2+ binding site [ion binding]; other site
1429244007273	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1429244007274	beta-D-glucuronidase; Provisional; Region: PRK10150
1429244007275	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1429244007276	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1429244007277	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244007278	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244007279	dimerization interface [polypeptide binding]; other site
1429244007280	putative DNA binding site [nucleotide binding]; other site
1429244007281	putative Zn2+ binding site [ion binding]; other site
1429244007282	Arginase-like amidino hydrolase family; Region: Arginase-like_1; cd09999
1429244007283	active site
1429244007284	Mn binding site [ion binding]; other site
1429244007285	Putative cyclase; Region: Cyclase; cl00814
1429244007286	Putative cyclase; Region: Cyclase; cl00814
1429244007287	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
1429244007288	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1429244007289	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1429244007290	dimer interface [polypeptide binding]; other site
1429244007291	active site
1429244007292	catalytic residue [active]
1429244007293	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244007294	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244007295	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244007296	dimerization interface [polypeptide binding]; other site
1429244007297	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244007298	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1429244007299	active site
1429244007300	FMN binding site [chemical binding]; other site
1429244007301	substrate binding site [chemical binding]; other site
1429244007302	homotetramer interface [polypeptide binding]; other site
1429244007303	catalytic residue [active]
1429244007304	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1429244007305	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244007306	active site
1429244007307	FMN binding site [chemical binding]; other site
1429244007308	substrate binding site [chemical binding]; other site
1429244007309	putative catalytic residue [active]
1429244007310	Spore germination protein; Region: Spore_permease; cl17796
1429244007311	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244007312	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244007313	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244007314	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244007315	MarR family; Region: MarR; pfam01047
1429244007316	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244007317	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244007318	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244007319	Walker A/P-loop; other site
1429244007320	ATP binding site [chemical binding]; other site
1429244007321	Q-loop/lid; other site
1429244007322	ABC transporter signature motif; other site
1429244007323	Walker B; other site
1429244007324	D-loop; other site
1429244007325	H-loop/switch region; other site
1429244007326	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244007327	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244007328	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1429244007329	Walker A/P-loop; other site
1429244007330	ATP binding site [chemical binding]; other site
1429244007331	Q-loop/lid; other site
1429244007332	ABC transporter signature motif; other site
1429244007333	Walker B; other site
1429244007334	D-loop; other site
1429244007335	H-loop/switch region; other site
1429244007336	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1429244007337	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
1429244007338	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1429244007339	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244007340	DNA-binding site [nucleotide binding]; DNA binding site
1429244007341	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244007342	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244007343	homodimer interface [polypeptide binding]; other site
1429244007344	catalytic residue [active]
1429244007345	AzlC protein; Region: AzlC; cl00570
1429244007346	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
1429244007347	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244007348	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244007349	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007350	dimer interface [polypeptide binding]; other site
1429244007351	conserved gate region; other site
1429244007352	putative PBP binding loops; other site
1429244007353	ABC-ATPase subunit interface; other site
1429244007354	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1429244007355	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1429244007356	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
1429244007357	Walker A/P-loop; other site
1429244007358	ATP binding site [chemical binding]; other site
1429244007359	Q-loop/lid; other site
1429244007360	ABC transporter signature motif; other site
1429244007361	Walker B; other site
1429244007362	D-loop; other site
1429244007363	H-loop/switch region; other site
1429244007364	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007365	putative PBP binding loops; other site
1429244007366	dimer interface [polypeptide binding]; other site
1429244007367	ABC-ATPase subunit interface; other site
1429244007368	Quinone oxidoreductase (QOR); Region: quinone_oxidoreductase_like_1; cd08243
1429244007369	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1429244007370	putative NAD(P) binding site [chemical binding]; other site
1429244007371	Right handed beta helix region; Region: Beta_helix; pfam13229
1429244007372	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244007373	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007374	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007375	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244007376	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244007377	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244007378	dimerization interface [polypeptide binding]; other site
1429244007379	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1429244007380	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244007381	beta-galactosidase; Region: BGL; TIGR03356
1429244007382	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244007383	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244007384	active site turn [active]
1429244007385	phosphorylation site [posttranslational modification]
1429244007386	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244007387	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244007388	HPr interaction site; other site
1429244007389	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244007390	active site
1429244007391	phosphorylation site [posttranslational modification]
1429244007392	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1429244007393	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1429244007394	inhibitor site; inhibition site
1429244007395	active site
1429244007396	dimer interface [polypeptide binding]; other site
1429244007397	catalytic residue [active]
1429244007398	Predicted membrane protein [Function unknown]; Region: COG2364
1429244007399	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244007400	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1429244007401	MarR family; Region: MarR; pfam01047
1429244007402	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1429244007403	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244007404	Coenzyme A binding pocket [chemical binding]; other site
1429244007405	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1429244007406	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1429244007407	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1429244007408	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1429244007409	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244007410	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1429244007411	classical (c) SDRs; Region: SDR_c; cd05233
1429244007412	NAD(P) binding site [chemical binding]; other site
1429244007413	active site
1429244007414	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; Region: 2-Hacid_dh_C; pfam02826
1429244007415	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007416	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007417	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244007418	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244007419	intersubunit interface [polypeptide binding]; other site
1429244007420	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244007421	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1429244007422	substrate binding site [chemical binding]; other site
1429244007423	nickel ABC transporter, permease subunit NikB; Region: nickel_nikB; TIGR02789
1429244007424	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007425	dimer interface [polypeptide binding]; other site
1429244007426	conserved gate region; other site
1429244007427	putative PBP binding loops; other site
1429244007428	ABC-ATPase subunit interface; other site
1429244007429	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1429244007430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007431	dimer interface [polypeptide binding]; other site
1429244007432	conserved gate region; other site
1429244007433	putative PBP binding loops; other site
1429244007434	ABC-ATPase subunit interface; other site
1429244007435	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1429244007436	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244007437	Walker A/P-loop; other site
1429244007438	ATP binding site [chemical binding]; other site
1429244007439	Q-loop/lid; other site
1429244007440	ABC transporter signature motif; other site
1429244007441	Walker B; other site
1429244007442	D-loop; other site
1429244007443	H-loop/switch region; other site
1429244007444	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1429244007445	nickel import ATP-binding protein NikE; Region: nickel_nikE; TIGR02769
1429244007446	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244007447	Walker A/P-loop; other site
1429244007448	ATP binding site [chemical binding]; other site
1429244007449	Q-loop/lid; other site
1429244007450	ABC transporter signature motif; other site
1429244007451	Walker B; other site
1429244007452	D-loop; other site
1429244007453	H-loop/switch region; other site
1429244007454	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244007455	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244007456	putative substrate translocation pore; other site
1429244007457	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1429244007458	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1429244007459	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244007460	NAD(P) binding site [chemical binding]; other site
1429244007461	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244007462	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244007463	Transcriptional regulator; Region: Rrf2; pfam02082
1429244007464	Rrf2 family protein; Region: rrf2_super; TIGR00738
1429244007465	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1429244007466	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244007467	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244007468	DNA binding site [nucleotide binding]
1429244007469	domain linker motif; other site
1429244007470	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
1429244007471	dimerization interface [polypeptide binding]; other site
1429244007472	ligand binding site [chemical binding]; other site
1429244007473	sodium binding site [ion binding]; other site
1429244007474	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1429244007475	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1429244007476	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1429244007477	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1429244007478	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244007479	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1429244007480	active site
1429244007481	motif I; other site
1429244007482	motif II; other site
1429244007483	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244007484	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1429244007485	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244007486	Walker A motif; other site
1429244007487	ATP binding site [chemical binding]; other site
1429244007488	Walker B motif; other site
1429244007489	arginine finger; other site
1429244007490	Transcriptional antiterminator [Transcription]; Region: COG3933
1429244007491	PRD domain; Region: PRD; pfam00874
1429244007492	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1429244007493	active pocket/dimerization site; other site
1429244007494	active site
1429244007495	phosphorylation site [posttranslational modification]
1429244007496	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1429244007497	active pocket/dimerization site; other site
1429244007498	active site
1429244007499	phosphorylation site [posttranslational modification]
1429244007500	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1429244007501	active site
1429244007502	phosphorylation site [posttranslational modification]
1429244007503	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1429244007504	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
1429244007505	Glycosyl hydrolases family 32 N-terminal domain; Region: Glyco_hydro_32N; pfam00251
1429244007506	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244007507	substrate binding [chemical binding]; other site
1429244007508	active site
1429244007509	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
1429244007510	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244007511	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
1429244007512	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1429244007513	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1429244007514	putative substrate binding site [chemical binding]; other site
1429244007515	putative ATP binding site [chemical binding]; other site
1429244007516	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244007517	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244007518	DNA binding site [nucleotide binding]
1429244007519	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1429244007520	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244007521	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007522	dimer interface [polypeptide binding]; other site
1429244007523	conserved gate region; other site
1429244007524	putative PBP binding loops; other site
1429244007525	ABC-ATPase subunit interface; other site
1429244007526	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244007527	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007528	dimer interface [polypeptide binding]; other site
1429244007529	conserved gate region; other site
1429244007530	putative PBP binding loops; other site
1429244007531	ABC-ATPase subunit interface; other site
1429244007532	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244007533	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
1429244007534	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244007535	substrate binding [chemical binding]; other site
1429244007536	active site
1429244007537	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244007538	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244007539	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244007540	PRD domain; Region: PRD; pfam00874
1429244007541	PRD domain; Region: PRD; pfam00874
1429244007542	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244007543	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244007544	active site turn [active]
1429244007545	phosphorylation site [posttranslational modification]
1429244007546	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244007547	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1429244007548	HPr interaction site; other site
1429244007549	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244007550	active site
1429244007551	phosphorylation site [posttranslational modification]
1429244007552	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244007553	beta-galactosidase; Region: BGL; TIGR03356
1429244007554	EthD domain; Region: EthD; pfam07110
1429244007555	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244007556	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007557	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1429244007558	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244007559	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1429244007560	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1429244007561	NAD binding site [chemical binding]; other site
1429244007562	substrate binding site [chemical binding]; other site
1429244007563	putative active site [active]
1429244007564	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1429244007565	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
1429244007566	catalytic residues [active]
1429244007567	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244007568	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244007569	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1429244007570	Arginase-like amidino hydrolase family; Region: Arginase-like_1; cd09999
1429244007571	active site
1429244007572	Mn binding site [ion binding]; other site
1429244007573	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244007574	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007575	active site
1429244007576	phosphorylation site [posttranslational modification]
1429244007577	intermolecular recognition site; other site
1429244007578	dimerization interface [polypeptide binding]; other site
1429244007579	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244007580	DNA binding site [nucleotide binding]
1429244007581	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244007582	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244007583	dimerization interface [polypeptide binding]; other site
1429244007584	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244007585	dimer interface [polypeptide binding]; other site
1429244007586	phosphorylation site [posttranslational modification]
1429244007587	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007588	ATP binding site [chemical binding]; other site
1429244007589	Mg2+ binding site [ion binding]; other site
1429244007590	G-X-G motif; other site
1429244007591	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244007592	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1429244007593	Walker A/P-loop; other site
1429244007594	ATP binding site [chemical binding]; other site
1429244007595	Q-loop/lid; other site
1429244007596	ABC transporter signature motif; other site
1429244007597	Walker B; other site
1429244007598	D-loop; other site
1429244007599	H-loop/switch region; other site
1429244007600	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1429244007601	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1429244007602	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1429244007603	FtsX-like permease family; Region: FtsX; pfam02687
1429244007604	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1429244007605	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1429244007606	active site
1429244007607	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
1429244007608	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007609	active site
1429244007610	phosphorylation site [posttranslational modification]
1429244007611	intermolecular recognition site; other site
1429244007612	dimerization interface [polypeptide binding]; other site
1429244007613	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007614	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007615	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244007616	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
1429244007617	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244007618	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007619	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1429244007620	ABC-ATPase subunit interface; other site
1429244007621	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244007622	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007623	ABC-ATPase subunit interface; other site
1429244007624	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
1429244007625	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1429244007626	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1429244007627	Histidine kinase; Region: HisKA_3; pfam07730
1429244007628	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007629	ATP binding site [chemical binding]; other site
1429244007630	Mg2+ binding site [ion binding]; other site
1429244007631	G-X-G motif; other site
1429244007632	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1429244007633	classical (c) SDRs; Region: SDR_c; cd05233
1429244007634	NAD(P) binding site [chemical binding]; other site
1429244007635	active site
1429244007636	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244007637	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
1429244007638	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244007639	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007640	ABC-ATPase subunit interface; other site
1429244007641	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244007642	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007643	dimer interface [polypeptide binding]; other site
1429244007644	conserved gate region; other site
1429244007645	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1429244007646	ABC-ATPase subunit interface; other site
1429244007647	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244007648	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007649	active site
1429244007650	phosphorylation site [posttranslational modification]
1429244007651	intermolecular recognition site; other site
1429244007652	dimerization interface [polypeptide binding]; other site
1429244007653	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007654	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007655	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244007656	HAMP domain; Region: HAMP; pfam00672
1429244007657	dimerization interface [polypeptide binding]; other site
1429244007658	Histidine kinase; Region: His_kinase; pfam06580
1429244007659	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007660	ATP binding site [chemical binding]; other site
1429244007661	Mg2+ binding site [ion binding]; other site
1429244007662	G-X-G motif; other site
1429244007663	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007664	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007665	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007666	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1429244007667	classical (c) SDRs; Region: SDR_c; cd05233
1429244007668	NAD(P) binding site [chemical binding]; other site
1429244007669	active site
1429244007670	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1429244007671	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
1429244007672	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1429244007673	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1429244007674	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1429244007675	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1429244007676	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1429244007677	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1429244007678	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1429244007679	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1429244007680	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1429244007681	Putative carbohydrate binding domain; Region: CBM_X; cl05621
1429244007682	N-terminal domain of glycoside hydrolase family 94 and related domains; Region: GH94N_like; cl17067
1429244007683	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1429244007684	Cytochrome P450; Region: p450; cl12078
1429244007685	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1429244007686	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1429244007687	NAD(P) binding site [chemical binding]; other site
1429244007688	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1429244007689	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244007690	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1429244007691	catalytic residues [active]
1429244007692	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244007693	dimerization interface [polypeptide binding]; other site
1429244007694	putative DNA binding site [nucleotide binding]; other site
1429244007695	putative Zn2+ binding site [ion binding]; other site
1429244007696	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1429244007697	active site residue [active]
1429244007698	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244007699	catalytic residues [active]
1429244007700	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1429244007701	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD_like; cd08296
1429244007702	putative NAD(P) binding site [chemical binding]; other site
1429244007703	putative substrate binding site [chemical binding]; other site
1429244007704	catalytic Zn binding site [ion binding]; other site
1429244007705	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244007706	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244007707	DNA binding site [nucleotide binding]
1429244007708	domain linker motif; other site
1429244007709	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1429244007710	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244007711	dimerization interface [polypeptide binding]; other site
1429244007712	putative DNA binding site [nucleotide binding]; other site
1429244007713	putative Zn2+ binding site [ion binding]; other site
1429244007714	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1429244007715	active site residue [active]
1429244007716	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1429244007717	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1429244007718	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244007719	OsmC-like protein; Region: OsmC; cl00767
1429244007720	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244007721	catalytic residues [active]
1429244007722	Old yellow enzyme (OYE)-related FMN binding domain, group 5.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_5_FMN; cd04747
1429244007723	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244007724	putative active site [active]
1429244007725	putative FMN binding site [chemical binding]; other site
1429244007726	putative substrate binding site [chemical binding]; other site
1429244007727	putative catalytic residue [active]
1429244007728	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1429244007729	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1429244007730	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1429244007731	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
1429244007732	catalytic residues [active]
1429244007733	OsmC-like protein; Region: OsmC; pfam02566
1429244007734	Spore germination protein; Region: Spore_permease; pfam03845
1429244007735	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244007736	OsmC-like protein; Region: OsmC; pfam02566
1429244007737	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244007738	MarR family; Region: MarR_2; pfam12802
1429244007739	23S ribosomal RNA 16S or 23S rRNA prediction is too short
1429244007740	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244007741	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244007742	dimerization interface [polypeptide binding]; other site
1429244007743	Histidine kinase; Region: His_kinase; pfam06580
1429244007744	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007745	ATP binding site [chemical binding]; other site
1429244007746	Mg2+ binding site [ion binding]; other site
1429244007747	G-X-G motif; other site
1429244007748	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007749	active site
1429244007750	phosphorylation site [posttranslational modification]
1429244007751	intermolecular recognition site; other site
1429244007752	dimerization interface [polypeptide binding]; other site
1429244007753	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244007754	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007755	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244007756	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007757	dimer interface [polypeptide binding]; other site
1429244007758	conserved gate region; other site
1429244007759	ABC-ATPase subunit interface; other site
1429244007760	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244007761	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007762	dimer interface [polypeptide binding]; other site
1429244007763	conserved gate region; other site
1429244007764	putative PBP binding loops; other site
1429244007765	ABC-ATPase subunit interface; other site
1429244007766	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244007767	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
1429244007768	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
1429244007769	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1429244007770	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1429244007771	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1429244007772	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1429244007773	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1429244007774	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1429244007775	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1429244007776	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1429244007777	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1429244007778	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1429244007779	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1429244007780	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1429244007781	Pectate lyase [Carbohydrate transport and metabolism]; Region: PelB; COG3866
1429244007782	Autoinducer synthetase; Region: Autoind_synth; cl17404
1429244007783	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244007784	Coenzyme A binding pocket [chemical binding]; other site
1429244007785	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244007786	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244007787	DNA binding site [nucleotide binding]
1429244007788	domain linker motif; other site
1429244007789	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
1429244007790	dimerization interface [polypeptide binding]; other site
1429244007791	ligand binding site [chemical binding]; other site
1429244007792	sodium binding site [ion binding]; other site
1429244007793	galactoside permease; Reviewed; Region: lacY; PRK09528
1429244007794	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244007795	putative substrate translocation pore; other site
1429244007796	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1429244007797	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244007798	substrate binding [chemical binding]; other site
1429244007799	active site
1429244007800	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244007801	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1429244007802	Ku protein, prokaryotic; Region: Ku_bact; TIGR02772
1429244007803	Ku-core domain; includes the central DNA-binding beta-barrels, polypeptide rings, and the C-terminal arm of Ku proteins. The Ku protein consists of two tightly associated homologous subunits, Ku70 and Ku80, and was originally identified as an autoantigen...; Region: KU; cl02666
1429244007804	DNA binding site [nucleotide binding]
1429244007805	heterodimer interface [polypeptide binding]; other site
1429244007806	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244007807	non-specific DNA binding site [nucleotide binding]; other site
1429244007808	salt bridge; other site
1429244007809	sequence-specific DNA binding site [nucleotide binding]; other site
1429244007810	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244007811	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244007812	salt bridge; other site
1429244007813	non-specific DNA binding site [nucleotide binding]; other site
1429244007814	sequence-specific DNA binding site [nucleotide binding]; other site
1429244007815	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
1429244007816	AAA ATPase domain; Region: AAA_16; pfam13191
1429244007817	AAA domain; Region: AAA_22; pfam13401
1429244007818	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
1429244007819	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1429244007820	active site
1429244007821	DNA binding site [nucleotide binding]
1429244007822	Int/Topo IB signature motif; other site
1429244007823	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244007824	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1429244007825	active site
1429244007826	ATP binding site [chemical binding]; other site
1429244007827	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244007828	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1429244007829	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1429244007830	nucleophilic elbow; other site
1429244007831	catalytic triad; other site
1429244007832	Condensation domain; Region: Condensation; pfam00668
1429244007833	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007834	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244007835	acyl-activating enzyme (AAE) consensus motif; other site
1429244007836	AMP binding site [chemical binding]; other site
1429244007837	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244007838	Condensation domain; Region: Condensation; pfam00668
1429244007839	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007840	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244007841	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244007842	acyl-activating enzyme (AAE) consensus motif; other site
1429244007843	AMP binding site [chemical binding]; other site
1429244007844	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244007845	Condensation domain; Region: Condensation; pfam00668
1429244007846	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007847	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244007848	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244007849	acyl-activating enzyme (AAE) consensus motif; other site
1429244007850	AMP binding site [chemical binding]; other site
1429244007851	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244007852	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1429244007853	Condensation domain; Region: Condensation; pfam00668
1429244007854	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007855	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244007856	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244007857	acyl-activating enzyme (AAE) consensus motif; other site
1429244007858	AMP binding site [chemical binding]; other site
1429244007859	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244007860	Condensation domain; Region: Condensation; pfam00668
1429244007861	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007862	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244007863	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244007864	acyl-activating enzyme (AAE) consensus motif; other site
1429244007865	AMP binding site [chemical binding]; other site
1429244007866	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244007867	Condensation domain; Region: Condensation; pfam00668
1429244007868	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007869	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244007870	acyl-activating enzyme (AAE) consensus motif; other site
1429244007871	AMP binding site [chemical binding]; other site
1429244007872	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244007873	Condensation domain; Region: Condensation; pfam00668
1429244007874	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007875	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1429244007876	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1429244007877	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244007878	active site
1429244007879	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
1429244007880	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1429244007881	beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 2, complex (x); Region: KR_2_FAS_SDR_x; cd08955
1429244007882	KR domain; Region: KR; pfam08659
1429244007883	putative NADP binding site [chemical binding]; other site
1429244007884	active site
1429244007885	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1429244007886	Condensation domain; Region: Condensation; pfam00668
1429244007887	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244007888	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244007889	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244007890	acyl-activating enzyme (AAE) consensus motif; other site
1429244007891	AMP binding site [chemical binding]; other site
1429244007892	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244007893	diaminobutyrate--2-oxoglutarate aminotransferase; Validated; Region: PRK09264
1429244007894	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1429244007895	inhibitor-cofactor binding pocket; inhibition site
1429244007896	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244007897	catalytic residue [active]
1429244007898	chitin-binding domain of Chi A1-like proteins; Region: ChiA1_BD; cd12214
1429244007899	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1429244007900	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1429244007901	catalytic residue [active]
1429244007902	Isochorismatase family; Region: Isochorismatase; pfam00857
1429244007903	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1429244007904	catalytic triad [active]
1429244007905	conserved cis-peptide bond; other site
1429244007906	Uncharacterized protein conserved in bacteria C-term(DUF2220); Region: DUF2220; pfam09983
1429244007907	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1429244007908	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1429244007909	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244007910	active site
1429244007911	phosphorylation site [posttranslational modification]
1429244007912	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1429244007913	PRD domain; Region: PRD; pfam00874
1429244007914	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1429244007915	active site
1429244007916	P-loop; other site
1429244007917	phosphorylation site [posttranslational modification]
1429244007918	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244007919	active site
1429244007920	phosphorylation site [posttranslational modification]
1429244007921	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
1429244007922	tetramer interface [polypeptide binding]; other site
1429244007923	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1429244007924	active site
1429244007925	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1429244007926	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1429244007927	putative NAD(P) binding site [chemical binding]; other site
1429244007928	catalytic Zn binding site [ion binding]; other site
1429244007929	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1429244007930	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1429244007931	substrate binding site [chemical binding]; other site
1429244007932	hexamer interface [polypeptide binding]; other site
1429244007933	metal binding site [ion binding]; metal-binding site
1429244007934	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1429244007935	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1429244007936	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1429244007937	active site
1429244007938	P-loop; other site
1429244007939	phosphorylation site [posttranslational modification]
1429244007940	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1429244007941	classical (c) SDRs; Region: SDR_c; cd05233
1429244007942	NAD(P) binding site [chemical binding]; other site
1429244007943	active site
1429244007944	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244007945	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244007946	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
1429244007947	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1429244007948	dimer interface [polypeptide binding]; other site
1429244007949	FMN binding site [chemical binding]; other site
1429244007950	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244007951	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244007952	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1429244007953	active site
1429244007954	DNA binding site [nucleotide binding]
1429244007955	Int/Topo IB signature motif; other site
1429244007956	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1429244007957	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1429244007958	Ca binding site [ion binding]; other site
1429244007959	active site
1429244007960	catalytic site [active]
1429244007961	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244007962	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007963	conserved gate region; other site
1429244007964	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1429244007965	ABC-ATPase subunit interface; other site
1429244007966	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244007967	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244007968	dimer interface [polypeptide binding]; other site
1429244007969	conserved gate region; other site
1429244007970	ABC-ATPase subunit interface; other site
1429244007971	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244007972	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244007973	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
1429244007974	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007975	active site
1429244007976	phosphorylation site [posttranslational modification]
1429244007977	intermolecular recognition site; other site
1429244007978	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244007979	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244007980	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244007981	active site
1429244007982	phosphorylation site [posttranslational modification]
1429244007983	intermolecular recognition site; other site
1429244007984	dimerization interface [polypeptide binding]; other site
1429244007985	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244007986	DNA binding site [nucleotide binding]
1429244007987	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
1429244007988	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1429244007989	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1429244007990	Ligand Binding Site [chemical binding]; other site
1429244007991	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1429244007992	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244007993	dimer interface [polypeptide binding]; other site
1429244007994	phosphorylation site [posttranslational modification]
1429244007995	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244007996	ATP binding site [chemical binding]; other site
1429244007997	Mg2+ binding site [ion binding]; other site
1429244007998	G-X-G motif; other site
1429244007999	Epoxide hydrolase N terminus; Region: EHN; pfam06441
1429244008000	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244008001	Glycosyl hydrolase family 43; Region: GH43_AXH_1; cd09003
1429244008002	substrate binding site [chemical binding]; other site
1429244008003	active site
1429244008004	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
1429244008005	metal binding site [ion binding]; metal-binding site
1429244008006	ligand binding site [chemical binding]; other site
1429244008007	Carbohydrate Binding Module families 36 (CBM36) and 6 (CBM6); appended mainly to glycoside hydrolase family 11 (GH11) domains; xylan binding; Region: CBM6_36_xylanase-like; cd04078
1429244008008	Ca binding site [ion binding]; other site
1429244008009	Ca binding site (active) [ion binding]; other site
1429244008010	ligand binding site [chemical binding]; other site
1429244008011	amidase; Validated; Region: PRK06565
1429244008012	Amidase; Region: Amidase; cl11426
1429244008013	Amidase; Region: Amidase; cl11426
1429244008014	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1429244008015	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1429244008016	active site
1429244008017	non-prolyl cis peptide bond; other site
1429244008018	phosphoenolpyruvate synthase; Validated; Region: PRK06241
1429244008019	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1429244008020	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1429244008021	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1429244008022	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244008023	DNA-binding site [nucleotide binding]; DNA binding site
1429244008024	FCD domain; Region: FCD; pfam07729
1429244008025	mannonate dehydratase; Provisional; Region: PRK03906
1429244008026	mannonate dehydratase; Region: uxuA; TIGR00695
1429244008027	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1429244008028	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1429244008029	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1429244008030	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1429244008031	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1429244008032	putative NAD(P) binding site [chemical binding]; other site
1429244008033	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244008034	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1429244008035	FMN binding site [chemical binding]; other site
1429244008036	active site
1429244008037	substrate binding site [chemical binding]; other site
1429244008038	catalytic residue [active]
1429244008039	classical (c) SDRs; Region: SDR_c; cd05233
1429244008040	NAD(P) binding site [chemical binding]; other site
1429244008041	active site
1429244008042	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244008043	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244008044	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244008045	active site
1429244008046	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244008047	catalytic tetrad [active]
1429244008048	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244008049	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244008050	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1429244008051	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244008052	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244008053	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244008054	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244008055	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244008056	DNA binding site [nucleotide binding]
1429244008057	domain linker motif; other site
1429244008058	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244008059	ligand binding site [chemical binding]; other site
1429244008060	dimerization interface [polypeptide binding]; other site
1429244008061	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244008062	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244008063	active site
1429244008064	catalytic tetrad [active]
1429244008065	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1429244008066	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244008067	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244008068	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244008069	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244008070	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244008071	active site
1429244008072	catalytic tetrad [active]
1429244008073	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1429244008074	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244008075	NAD(P) binding site [chemical binding]; other site
1429244008076	active site
1429244008077	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1429244008078	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1429244008079	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244008080	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244008081	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244008082	putative oxidoreductase; Provisional; Region: PRK10206
1429244008083	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244008084	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244008085	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1429244008086	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1429244008087	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1429244008088	putative active site [active]
1429244008089	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1429244008090	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244008091	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1429244008092	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1429244008093	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1429244008094	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1429244008095	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
1429244008096	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244008097	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244008098	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244008099	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244008100	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244008101	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244008102	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244008103	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244008104	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1429244008105	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244008106	DNA binding residues [nucleotide binding]
1429244008107	putative dimer interface [polypeptide binding]; other site
1429244008108	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244008109	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244008110	active site
1429244008111	catalytic tetrad [active]
1429244008112	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244008113	Interdomain contacts; other site
1429244008114	Cytokine receptor motif; other site
1429244008115	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244008116	integral membrane protein; Region: integ_memb_HG; TIGR03954
1429244008117	YolD-like protein; Region: YolD; pfam08863
1429244008118	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244008119	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244008120	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244008121	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1429244008122	putative substrate translocation pore; other site
1429244008123	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_3; cd08490
1429244008124	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1429244008125	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244008126	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244008127	dimer interface [polypeptide binding]; other site
1429244008128	conserved gate region; other site
1429244008129	putative PBP binding loops; other site
1429244008130	ABC-ATPase subunit interface; other site
1429244008131	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1429244008132	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244008133	dimer interface [polypeptide binding]; other site
1429244008134	conserved gate region; other site
1429244008135	putative PBP binding loops; other site
1429244008136	ABC-ATPase subunit interface; other site
1429244008137	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1429244008138	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244008139	Walker A/P-loop; other site
1429244008140	ATP binding site [chemical binding]; other site
1429244008141	Q-loop/lid; other site
1429244008142	ABC transporter signature motif; other site
1429244008143	Walker B; other site
1429244008144	D-loop; other site
1429244008145	H-loop/switch region; other site
1429244008146	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1429244008147	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244008148	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1429244008149	Walker A/P-loop; other site
1429244008150	ATP binding site [chemical binding]; other site
1429244008151	Q-loop/lid; other site
1429244008152	ABC transporter signature motif; other site
1429244008153	Walker B; other site
1429244008154	D-loop; other site
1429244008155	H-loop/switch region; other site
1429244008156	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1429244008157	putative efflux protein, MATE family; Region: matE; TIGR00797
1429244008158	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1429244008159	AAA domain; Region: AAA_33; pfam13671
1429244008160	ligand-binding site [chemical binding]; other site
1429244008161	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4295
1429244008162	Uncharacterized protein conserved in bacteria (DUF2263); Region: DUF2263; pfam10021
1429244008163	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
1429244008164	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
1429244008165	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1429244008166	nudix motif; other site
1429244008167	Domain of unknown function (DUF1835); Region: DUF1835; pfam08874
1429244008168	Protein of unknown function; Region: DUF3658; pfam12395
1429244008169	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1429244008170	glutaminase A; Region: Gln_ase; TIGR03814
1429244008171	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
1429244008172	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
1429244008173	putative metal binding site [ion binding]; other site
1429244008174	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1429244008175	active site
1429244008176	Predicted membrane protein [Function unknown]; Region: COG2259
1429244008177	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1429244008178	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244008179	non-specific DNA binding site [nucleotide binding]; other site
1429244008180	salt bridge; other site
1429244008181	sequence-specific DNA binding site [nucleotide binding]; other site
1429244008182	Cupin domain; Region: Cupin_2; pfam07883
1429244008183	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
1429244008184	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
1429244008185	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1429244008186	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244008187	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
1429244008188	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1429244008189	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1429244008190	NAD(P) binding site [chemical binding]; other site
1429244008191	putative active site [active]
1429244008192	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1429244008193	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244008194	NAD(P) binding site [chemical binding]; other site
1429244008195	active site
1429244008196	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244008197	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1429244008198	active site
1429244008199	FMN binding site [chemical binding]; other site
1429244008200	substrate binding site [chemical binding]; other site
1429244008201	homotetramer interface [polypeptide binding]; other site
1429244008202	catalytic residue [active]
1429244008203	Cytochrome P450; Region: p450; cl12078
1429244008204	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1429244008205	MarR family; Region: MarR_2; pfam12802
1429244008206	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1429244008207	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1429244008208	catalytic residues [active]
1429244008209	catalytic nucleophile [active]
1429244008210	Presynaptic Site I dimer interface [polypeptide binding]; other site
1429244008211	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1429244008212	Synaptic Flat tetramer interface [polypeptide binding]; other site
1429244008213	Synaptic Site I dimer interface [polypeptide binding]; other site
1429244008214	DNA binding site [nucleotide binding]
1429244008215	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1429244008216	DNA-binding interface [nucleotide binding]; DNA binding site
1429244008217	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1429244008218	potassium/proton antiporter; Reviewed; Region: PRK05326
1429244008219	TrkA-C domain; Region: TrkA_C; pfam02080
1429244008220	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1429244008221	Class II fumarases; Region: Fumarase_classII; cd01362
1429244008222	active site
1429244008223	tetramer interface [polypeptide binding]; other site
1429244008224	2-isopropylmalate synthase; Validated; Region: PRK00915
1429244008225	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1429244008226	active site
1429244008227	catalytic residues [active]
1429244008228	metal binding site [ion binding]; metal-binding site
1429244008229	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1429244008230	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1429244008231	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244008232	DNA-binding site [nucleotide binding]; DNA binding site
1429244008233	FCD domain; Region: FCD; pfam07729
1429244008234	aldose 1-epimerase superfamily; Region: Aldose_epim; cd01081
1429244008235	active site
1429244008236	catalytic residues [active]
1429244008237	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244008238	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1429244008239	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1429244008240	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1429244008241	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1429244008242	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1429244008243	dimer interface [polypeptide binding]; other site
1429244008244	active site
1429244008245	metal binding site [ion binding]; metal-binding site
1429244008246	biotin synthase; Validated; Region: PRK06256
1429244008247	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244008248	FeS/SAM binding site; other site
1429244008249	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1429244008250	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1429244008251	Domain of unknown function DUF21; Region: DUF21; pfam01595
1429244008252	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1429244008253	Transporter associated domain; Region: CorC_HlyC; smart01091
1429244008254	Spore coat protein (Spore_GerQ); Region: Spore_GerQ; pfam09671
1429244008255	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1429244008256	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1429244008257	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244008258	NAD(P) binding site [chemical binding]; other site
1429244008259	active site
1429244008260	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1429244008261	Ycf48-like protein; Provisional; Region: PRK13684
1429244008262	Ycf48-like protein; Provisional; Region: PRK13684
1429244008263	amino acid transporter; Region: 2A0306; TIGR00909
1429244008264	Spore germination protein; Region: Spore_permease; cl17796
1429244008265	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
1429244008266	A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292
1429244008267	NAD binding site [chemical binding]; other site
1429244008268	dimer interface [polypeptide binding]; other site
1429244008269	substrate binding site [chemical binding]; other site
1429244008270	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244008271	Protein of unknown function (DUF3900); Region: DUF3900; pfam13039
1429244008272	Domain of unknown function (DUF3898); Region: DUF3898; pfam13037
1429244008273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244008274	H+ Antiporter protein; Region: 2A0121; TIGR00900
1429244008275	putative substrate translocation pore; other site
1429244008276	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244008277	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244008278	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244008279	dimerization interface [polypeptide binding]; other site
1429244008280	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244008281	dimer interface [polypeptide binding]; other site
1429244008282	phosphorylation site [posttranslational modification]
1429244008283	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244008284	ATP binding site [chemical binding]; other site
1429244008285	Mg2+ binding site [ion binding]; other site
1429244008286	G-X-G motif; other site
1429244008287	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244008288	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244008289	active site
1429244008290	phosphorylation site [posttranslational modification]
1429244008291	intermolecular recognition site; other site
1429244008292	dimerization interface [polypeptide binding]; other site
1429244008293	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244008294	DNA binding site [nucleotide binding]
1429244008295	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1429244008296	active site
1429244008297	P-loop; other site
1429244008298	phosphorylation site [posttranslational modification]
1429244008299	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1429244008300	Coenzyme A transferase; Region: CoA_trans; smart00882
1429244008301	Coenzyme A transferase; Region: CoA_trans; cl17247
1429244008302	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1429244008303	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244008304	putative substrate translocation pore; other site
1429244008305	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1429244008306	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1429244008307	FMN binding site [chemical binding]; other site
1429244008308	substrate binding site [chemical binding]; other site
1429244008309	putative catalytic residue [active]
1429244008310	PAS domain; Region: PAS_9; pfam13426
1429244008311	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1429244008312	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244008313	Walker A motif; other site
1429244008314	ATP binding site [chemical binding]; other site
1429244008315	Walker B motif; other site
1429244008316	arginine finger; other site
1429244008317	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1429244008318	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1429244008319	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244008320	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1429244008321	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244008322	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244008323	Walker A/P-loop; other site
1429244008324	ATP binding site [chemical binding]; other site
1429244008325	Q-loop/lid; other site
1429244008326	ABC transporter signature motif; other site
1429244008327	Walker B; other site
1429244008328	D-loop; other site
1429244008329	H-loop/switch region; other site
1429244008330	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244008331	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1429244008332	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244008333	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244008334	active site
1429244008335	phosphorylation site [posttranslational modification]
1429244008336	intermolecular recognition site; other site
1429244008337	dimerization interface [polypeptide binding]; other site
1429244008338	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244008339	DNA binding site [nucleotide binding]
1429244008340	DNA-binding domain of DNA mismatch repair MUTS family; Region: MUTSd; smart00533
1429244008341	MutS domain III; Region: MutS_III; pfam05192
1429244008342	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244008343	Walker A/P-loop; other site
1429244008344	ATP binding site [chemical binding]; other site
1429244008345	Q-loop/lid; other site
1429244008346	ABC transporter signature motif; other site
1429244008347	Walker B; other site
1429244008348	D-loop; other site
1429244008349	H-loop/switch region; other site
1429244008350	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1429244008351	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244008352	nucleotide binding site [chemical binding]; other site
1429244008353	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1429244008354	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1429244008355	active site
1429244008356	motif I; other site
1429244008357	motif II; other site
1429244008358	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1429244008359	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1429244008360	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1429244008361	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1429244008362	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1429244008363	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1429244008364	active site
1429244008365	DNA binding site [nucleotide binding]
1429244008366	Int/Topo IB signature motif; other site
1429244008367	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244008368	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244008369	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244008370	ABC-ATPase subunit  interface; other site
1429244008371	dimer interface [polypeptide binding]; other site
1429244008372	putative PBP binding regions; other site
1429244008373	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244008374	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244008375	ABC-ATPase subunit  interface; other site
1429244008376	dimer interface [polypeptide binding]; other site
1429244008377	putative PBP binding regions; other site
1429244008378	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244008379	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244008380	intersubunit interface [polypeptide binding]; other site
1429244008381	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244008382	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244008383	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1429244008384	Walker A/P-loop; other site
1429244008385	ATP binding site [chemical binding]; other site
1429244008386	Q-loop/lid; other site
1429244008387	ABC transporter signature motif; other site
1429244008388	Walker B; other site
1429244008389	D-loop; other site
1429244008390	H-loop/switch region; other site
1429244008391	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244008392	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244008393	intersubunit interface [polypeptide binding]; other site
1429244008394	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1429244008395	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1429244008396	ligand binding site [chemical binding]; other site
1429244008397	dimerization interface [polypeptide binding]; other site
1429244008398	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1429244008399	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1429244008400	TM-ABC transporter signature motif; other site
1429244008401	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1429244008402	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1429244008403	Walker A/P-loop; other site
1429244008404	ATP binding site [chemical binding]; other site
1429244008405	Q-loop/lid; other site
1429244008406	ABC transporter signature motif; other site
1429244008407	Walker B; other site
1429244008408	D-loop; other site
1429244008409	H-loop/switch region; other site
1429244008410	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1429244008411	D-ribose pyranase; Provisional; Region: PRK11797
1429244008412	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1429244008413	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1429244008414	substrate binding site [chemical binding]; other site
1429244008415	dimer interface [polypeptide binding]; other site
1429244008416	ATP binding site [chemical binding]; other site
1429244008417	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244008418	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244008419	DNA binding site [nucleotide binding]
1429244008420	domain linker motif; other site
1429244008421	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1429244008422	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1429244008423	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
1429244008424	catalytic residues [active]
1429244008425	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1429244008426	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344
1429244008427	putative NAD(P) binding site [chemical binding]; other site
1429244008428	putative active site [active]
1429244008429	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244008430	Predicted permeases [General function prediction only]; Region: COG0679
1429244008431	BNR repeat-like domain; Region: BNR_2; pfam13088
1429244008432	Carbohydrate binding domain X2; Region: CBM_X2; pfam03442
1429244008433	Cellulose binding domain; Region: CBM_3; pfam00942
1429244008434	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244008435	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1429244008436	metal binding site [ion binding]; metal-binding site
1429244008437	dimer interface [polypeptide binding]; other site
1429244008438	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244008439	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244008440	Walker A/P-loop; other site
1429244008441	ATP binding site [chemical binding]; other site
1429244008442	Q-loop/lid; other site
1429244008443	ABC transporter signature motif; other site
1429244008444	Walker B; other site
1429244008445	D-loop; other site
1429244008446	H-loop/switch region; other site
1429244008447	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244008448	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1429244008449	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244008450	Walker A/P-loop; other site
1429244008451	ATP binding site [chemical binding]; other site
1429244008452	Q-loop/lid; other site
1429244008453	ABC transporter signature motif; other site
1429244008454	Walker B; other site
1429244008455	D-loop; other site
1429244008456	H-loop/switch region; other site
1429244008457	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244008458	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1429244008459	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244008460	dimer interface [polypeptide binding]; other site
1429244008461	conserved gate region; other site
1429244008462	ABC-ATPase subunit interface; other site
1429244008463	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244008464	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244008465	dimer interface [polypeptide binding]; other site
1429244008466	conserved gate region; other site
1429244008467	putative PBP binding loops; other site
1429244008468	ABC-ATPase subunit interface; other site
1429244008469	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244008470	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
1429244008471	Predicted acetyltransferase [General function prediction only]; Region: COG5628
1429244008472	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
1429244008473	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1429244008474	active site
1429244008475	DNA binding site [nucleotide binding]
1429244008476	Int/Topo IB signature motif; other site
1429244008477	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1429244008478	Walker A motif; other site
1429244008479	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1429244008480	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1429244008481	dimer interface [polypeptide binding]; other site
1429244008482	putative functional site; other site
1429244008483	putative MPT binding site; other site
1429244008484	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
1429244008485	putative hydrophobic ligand binding site [chemical binding]; other site
1429244008486	Domain of unknown function (DUF4247); Region: DUF4247; pfam14042
1429244008487	Domain of unknown function (DUF4178); Region: DUF4178; pfam13785
1429244008488	Predicted membrane protein [Function unknown]; Region: COG3766
1429244008489	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1429244008490	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244008491	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1429244008492	active site
1429244008493	FMN binding site [chemical binding]; other site
1429244008494	substrate binding site [chemical binding]; other site
1429244008495	homotetramer interface [polypeptide binding]; other site
1429244008496	catalytic residue [active]
1429244008497	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
1429244008498	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1429244008499	NodB motif; other site
1429244008500	active site
1429244008501	catalytic site [active]
1429244008502	metal binding site [ion binding]; metal-binding site
1429244008503	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244008504	3D domain; Region: 3D; cl01439
1429244008505	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244008506	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244008507	Walker A/P-loop; other site
1429244008508	ATP binding site [chemical binding]; other site
1429244008509	Q-loop/lid; other site
1429244008510	ABC transporter signature motif; other site
1429244008511	Walker B; other site
1429244008512	D-loop; other site
1429244008513	H-loop/switch region; other site
1429244008514	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244008515	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244008516	substrate binding pocket [chemical binding]; other site
1429244008517	membrane-bound complex binding site; other site
1429244008518	hinge residues; other site
1429244008519	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1429244008520	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244008521	dimer interface [polypeptide binding]; other site
1429244008522	conserved gate region; other site
1429244008523	putative PBP binding loops; other site
1429244008524	ABC-ATPase subunit interface; other site
1429244008525	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244008526	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
1429244008527	metal binding site [ion binding]; metal-binding site
1429244008528	Uncharacterized conserved protein [Function unknown]; Region: COG4278
1429244008529	glycogen synthase; Provisional; Region: glgA; PRK00654
1429244008530	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1429244008531	ADP-binding pocket [chemical binding]; other site
1429244008532	homodimer interface [polypeptide binding]; other site
1429244008533	glycogen branching enzyme; Provisional; Region: PRK12313
1429244008534	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1429244008535	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1429244008536	active site
1429244008537	catalytic site [active]
1429244008538	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1429244008539	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
1429244008540	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1429244008541	ligand binding site; other site
1429244008542	oligomer interface; other site
1429244008543	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1429244008544	N-terminal domain interface [polypeptide binding]; other site
1429244008545	sulfate 1 binding site; other site
1429244008546	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244008547	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244008548	dimerization interface [polypeptide binding]; other site
1429244008549	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244008550	dimer interface [polypeptide binding]; other site
1429244008551	phosphorylation site [posttranslational modification]
1429244008552	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244008553	ATP binding site [chemical binding]; other site
1429244008554	Mg2+ binding site [ion binding]; other site
1429244008555	G-X-G motif; other site
1429244008556	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244008557	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244008558	active site
1429244008559	phosphorylation site [posttranslational modification]
1429244008560	intermolecular recognition site; other site
1429244008561	dimerization interface [polypeptide binding]; other site
1429244008562	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244008563	DNA binding site [nucleotide binding]
1429244008564	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
1429244008565	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244008566	Walker A/P-loop; other site
1429244008567	ATP binding site [chemical binding]; other site
1429244008568	Q-loop/lid; other site
1429244008569	ABC transporter signature motif; other site
1429244008570	Walker B; other site
1429244008571	D-loop; other site
1429244008572	H-loop/switch region; other site
1429244008573	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244008574	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244008575	putative substrate translocation pore; other site
1429244008576	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1429244008577	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244008578	motif II; other site
1429244008579	DNA topoisomerase III; Provisional; Region: PRK07726
1429244008580	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1429244008581	active site
1429244008582	putative interdomain interaction site [polypeptide binding]; other site
1429244008583	putative metal-binding site [ion binding]; other site
1429244008584	putative nucleotide binding site [chemical binding]; other site
1429244008585	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1429244008586	domain I; other site
1429244008587	DNA binding groove [nucleotide binding]
1429244008588	phosphate binding site [ion binding]; other site
1429244008589	domain II; other site
1429244008590	domain III; other site
1429244008591	nucleotide binding site [chemical binding]; other site
1429244008592	catalytic site [active]
1429244008593	domain IV; other site
1429244008594	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1429244008595	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
1429244008596	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244008597	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1429244008598	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1429244008599	folate binding site [chemical binding]; other site
1429244008600	NADP+ binding site [chemical binding]; other site
1429244008601	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1429244008602	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1429244008603	dimerization interface [polypeptide binding]; other site
1429244008604	active site
1429244008605	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1429244008606	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1429244008607	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244008608	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1429244008609	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
1429244008610	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1429244008611	E3 interaction surface; other site
1429244008612	lipoyl attachment site [posttranslational modification]; other site
1429244008613	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1429244008614	E3 interaction surface; other site
1429244008615	lipoyl attachment site [posttranslational modification]; other site
1429244008616	e3 binding domain; Region: E3_binding; pfam02817
1429244008617	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1429244008618	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1429244008619	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1429244008620	alpha subunit interface [polypeptide binding]; other site
1429244008621	TPP binding site [chemical binding]; other site
1429244008622	heterodimer interface [polypeptide binding]; other site
1429244008623	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1429244008624	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1429244008625	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1429244008626	TPP-binding site [chemical binding]; other site
1429244008627	heterodimer interface [polypeptide binding]; other site
1429244008628	tetramer interface [polypeptide binding]; other site
1429244008629	phosphorylation loop region [posttranslational modification]
1429244008630	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1429244008631	Putative esterase; Region: Esterase; pfam00756
1429244008632	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1429244008633	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1429244008634	active site
1429244008635	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
1429244008636	Thiamine pyrophosphokinase; Region: TPK; cd07995
1429244008637	active site
1429244008638	dimerization interface [polypeptide binding]; other site
1429244008639	thiamine binding site [chemical binding]; other site
1429244008640	NlpC/P60 family; Region: NLPC_P60; pfam00877
1429244008641	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244008642	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244008643	active site
1429244008644	phosphorylation site [posttranslational modification]
1429244008645	dimerization interface [polypeptide binding]; other site
1429244008646	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244008647	DNA binding site [nucleotide binding]
1429244008648	thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688
1429244008649	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1429244008650	ATP binding site [chemical binding]; other site
1429244008651	substrate interface [chemical binding]; other site
1429244008652	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1429244008653	ThiS interaction site; other site
1429244008654	putative active site [active]
1429244008655	tetramer interface [polypeptide binding]; other site
1429244008656	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1429244008657	thiS-thiF/thiG interaction site; other site
1429244008658	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
1429244008659	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1429244008660	active site
1429244008661	thiamine phosphate binding site [chemical binding]; other site
1429244008662	pyrophosphate binding site [ion binding]; other site
1429244008663	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1429244008664	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244008665	Walker A/P-loop; other site
1429244008666	ATP binding site [chemical binding]; other site
1429244008667	Q-loop/lid; other site
1429244008668	ABC transporter signature motif; other site
1429244008669	Walker B; other site
1429244008670	D-loop; other site
1429244008671	H-loop/switch region; other site
1429244008672	ABC transporter; Region: ABC_tran_2; pfam12848
1429244008673	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244008674	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
1429244008675	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1429244008676	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1429244008677	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1429244008678	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1429244008679	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1429244008680	active site
1429244008681	ATP binding site [chemical binding]; other site
1429244008682	substrate binding site [chemical binding]; other site
1429244008683	activation loop (A-loop); other site
1429244008684	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1429244008685	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244008686	S-adenosylmethionine binding site [chemical binding]; other site
1429244008687	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244008688	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1429244008689	Walker A/P-loop; other site
1429244008690	ATP binding site [chemical binding]; other site
1429244008691	Q-loop/lid; other site
1429244008692	ABC transporter signature motif; other site
1429244008693	Walker B; other site
1429244008694	D-loop; other site
1429244008695	H-loop/switch region; other site
1429244008696	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244008697	catalytic residues [active]
1429244008698	AP endonuclease family 2; Region: AP2Ec; smart00518
1429244008699	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1429244008700	AP (apurinic/apyrimidinic) site pocket; other site
1429244008701	DNA interaction; other site
1429244008702	Metal-binding active site; metal-binding site
1429244008703	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
1429244008704	N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases; Region: FpgNei_N; cl03119
1429244008705	DNA binding site [nucleotide binding]
1429244008706	catalytic residue [active]
1429244008707	H2TH interface [polypeptide binding]; other site
1429244008708	putative catalytic residues [active]
1429244008709	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1429244008710	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244008711	Haloacid Dehalogenase Superfamily Class (subfamily) IIA; Region: HAD-SF-IIA; TIGR01460
1429244008712	active site
1429244008713	motif I; other site
1429244008714	motif II; other site
1429244008715	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244008716	ribonuclease Z; Region: RNase_Z; TIGR02651
1429244008717	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1429244008718	5-methyltetrahydrofolate--homocysteine methyltransferase; Region: metH; TIGR02082
1429244008719	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
1429244008720	substrate binding pocket [chemical binding]; other site
1429244008721	dimer interface [polypeptide binding]; other site
1429244008722	inhibitor binding site; inhibition site
1429244008723	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1429244008724	B12 binding site [chemical binding]; other site
1429244008725	cobalt ligand [ion binding]; other site
1429244008726	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1429244008727	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
1429244008728	Cupin domain; Region: Cupin_2; pfam07883
1429244008729	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1429244008730	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244008731	motif II; other site
1429244008732	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1429244008733	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244008734	LexA repressor; Validated; Region: PRK00215
1429244008735	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244008736	putative DNA binding site [nucleotide binding]; other site
1429244008737	putative Zn2+ binding site [ion binding]; other site
1429244008738	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1429244008739	Catalytic site [active]
1429244008740	PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; Region: PLAT; cl00011
1429244008741	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
1429244008742	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
1429244008743	Kelch motif; Region: Kelch_1; pfam01344
1429244008744	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
1429244008745	Kelch domain; Region: Kelch; smart00612
1429244008746	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
1429244008747	Kelch domain; Region: Kelch; smart00612
1429244008748	Kelch motif; Region: Kelch_1; pfam01344
1429244008749	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1429244008750	beta-galactosidase; Region: BGL; TIGR03356
1429244008751	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244008752	HPr interaction site; other site
1429244008753	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244008754	active site
1429244008755	phosphorylation site [posttranslational modification]
1429244008756	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
1429244008757	active site turn [active]
1429244008758	phosphorylation site [posttranslational modification]
1429244008759	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1429244008760	MepB protein; Region: MepB; cl01985
1429244008761	DinB family; Region: DinB; cl17821
1429244008762	DinB superfamily; Region: DinB_2; pfam12867
1429244008763	glutamine synthetase, type I; Region: GlnA; TIGR00653
1429244008764	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1429244008765	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1429244008766	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
1429244008767	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244008768	DNA binding residues [nucleotide binding]
1429244008769	putative dimer interface [polypeptide binding]; other site
1429244008770	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
1429244008771	Aluminium resistance protein; Region: Alum_res; pfam06838
1429244008772	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1429244008773	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1429244008774	HflX GTPase family; Region: HflX; cd01878
1429244008775	G1 box; other site
1429244008776	GTP/Mg2+ binding site [chemical binding]; other site
1429244008777	Switch I region; other site
1429244008778	G2 box; other site
1429244008779	G3 box; other site
1429244008780	Switch II region; other site
1429244008781	G4 box; other site
1429244008782	G5 box; other site
1429244008783	stage V sporulation protein K; Region: spore_V_K; TIGR02881
1429244008784	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244008785	Walker A motif; other site
1429244008786	ATP binding site [chemical binding]; other site
1429244008787	Walker B motif; other site
1429244008788	arginine finger; other site
1429244008789	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1429244008790	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1429244008791	putative active site [active]
1429244008792	Protein of unknown function (DUF402); Region: DUF402; cl00979
1429244008793	Transglycosylase; Region: Transgly; pfam00912
1429244008794	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1429244008795	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1429244008796	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244008797	Interdomain contacts; other site
1429244008798	Cytokine receptor motif; other site
1429244008799	bacterial Hfq-like; Region: Hfq; cd01716
1429244008800	hexamer interface [polypeptide binding]; other site
1429244008801	Sm1 motif; other site
1429244008802	RNA binding site [nucleotide binding]; other site
1429244008803	Sm2 motif; other site
1429244008804	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1429244008805	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1429244008806	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244008807	S-adenosylmethionine binding site [chemical binding]; other site
1429244008808	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
1429244008809	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244008810	ATP binding site [chemical binding]; other site
1429244008811	Mg2+ binding site [ion binding]; other site
1429244008812	G-X-G motif; other site
1429244008813	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1429244008814	ATP binding site [chemical binding]; other site
1429244008815	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1429244008816	Phage phiEco32-like COOH.NH2 ligase-type 2; Region: COOH-NH2_lig; pfam14395
1429244008817	Outer spore coat protein E (CotE); Region: CotE; pfam10628
1429244008818	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244008819	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244008820	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244008821	dimerization interface [polypeptide binding]; other site
1429244008822	putative transporter; Provisional; Region: PRK11021
1429244008823	Predicted membrane protein [Function unknown]; Region: COG4129
1429244008824	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1429244008825	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
1429244008826	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1429244008827	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244008828	dimer interface [polypeptide binding]; other site
1429244008829	conserved gate region; other site
1429244008830	putative PBP binding loops; other site
1429244008831	ABC-ATPase subunit interface; other site
1429244008832	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1429244008833	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1429244008834	Walker A/P-loop; other site
1429244008835	ATP binding site [chemical binding]; other site
1429244008836	Q-loop/lid; other site
1429244008837	ABC transporter signature motif; other site
1429244008838	Walker B; other site
1429244008839	D-loop; other site
1429244008840	H-loop/switch region; other site
1429244008841	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1429244008842	NMT1-like family; Region: NMT1_2; pfam13379
1429244008843	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1429244008844	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1429244008845	active site
1429244008846	Zn binding site [ion binding]; other site
1429244008847	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
1429244008848	active site clefts [active]
1429244008849	zinc binding site [ion binding]; other site
1429244008850	dimer interface [polypeptide binding]; other site
1429244008851	Predicted transcriptional regulators [Transcription]; Region: COG1695
1429244008852	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1429244008853	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1429244008854	Protein of unknown function (DUF2653); Region: DUF2653; pfam10850
1429244008855	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
1429244008856	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244008857	FeS/SAM binding site; other site
1429244008858	coproporphyrinogen III oxidase; Validated; Region: PRK08208
1429244008859	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244008860	FeS/SAM binding site; other site
1429244008861	HemN C-terminal domain; Region: HemN_C; pfam06969
1429244008862	Sulfatase; Region: Sulfatase; cl17466
1429244008863	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1429244008864	Substrate binding site [chemical binding]; other site
1429244008865	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1429244008866	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244008867	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244008868	putative membrane fusion protein; Region: TIGR02828
1429244008869	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1429244008870	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244008871	putative substrate translocation pore; other site
1429244008872	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1429244008873	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1429244008874	E3 interaction surface; other site
1429244008875	lipoyl attachment site [posttranslational modification]; other site
1429244008876	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244008877	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1429244008878	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1429244008879	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1429244008880	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1429244008881	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1429244008882	active site
1429244008883	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244008884	MarR family; Region: MarR; pfam01047
1429244008885	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1429244008886	MarR family; Region: MarR; pfam01047
1429244008887	DNA gyrase subunit A; Validated; Region: PRK05560
1429244008888	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1429244008889	CAP-like domain; other site
1429244008890	active site
1429244008891	primary dimer interface [polypeptide binding]; other site
1429244008892	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244008893	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244008894	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244008895	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1429244008896	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244008897	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
1429244008898	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244008899	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244008900	Walker A/P-loop; other site
1429244008901	ATP binding site [chemical binding]; other site
1429244008902	Q-loop/lid; other site
1429244008903	ABC transporter signature motif; other site
1429244008904	Walker B; other site
1429244008905	D-loop; other site
1429244008906	H-loop/switch region; other site
1429244008907	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1429244008908	active site
1429244008909	catalytic triad [active]
1429244008910	oxyanion hole [active]
1429244008911	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
1429244008912	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
1429244008913	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1429244008914	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244008915	Coenzyme A binding pocket [chemical binding]; other site
1429244008916	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1429244008917	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244008918	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1429244008919	ATP-grasp domain; Region: ATP-grasp; pfam02222
1429244008920	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244008921	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244008922	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1429244008923	Walker A/P-loop; other site
1429244008924	ATP binding site [chemical binding]; other site
1429244008925	Q-loop/lid; other site
1429244008926	ABC transporter signature motif; other site
1429244008927	Walker B; other site
1429244008928	D-loop; other site
1429244008929	H-loop/switch region; other site
1429244008930	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244008931	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244008932	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244008933	Walker A/P-loop; other site
1429244008934	ATP binding site [chemical binding]; other site
1429244008935	Q-loop/lid; other site
1429244008936	ABC transporter signature motif; other site
1429244008937	Walker B; other site
1429244008938	D-loop; other site
1429244008939	H-loop/switch region; other site
1429244008940	Protein of unknown function, DUF258; Region: DUF258; pfam03193
1429244008941	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1429244008942	Dynamin family; Region: Dynamin_N; pfam00350
1429244008943	G1 box; other site
1429244008944	GTP/Mg2+ binding site [chemical binding]; other site
1429244008945	G2 box; other site
1429244008946	Switch I region; other site
1429244008947	G3 box; other site
1429244008948	Switch II region; other site
1429244008949	G4 box; other site
1429244008950	G5 box; other site
1429244008951	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1429244008952	Dynamin family; Region: Dynamin_N; pfam00350
1429244008953	G1 box; other site
1429244008954	GTP/Mg2+ binding site [chemical binding]; other site
1429244008955	G2 box; other site
1429244008956	Switch I region; other site
1429244008957	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1429244008958	G3 box; other site
1429244008959	Switch II region; other site
1429244008960	GTP/Mg2+ binding site [chemical binding]; other site
1429244008961	G4 box; other site
1429244008962	G5 box; other site
1429244008963	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1429244008964	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1429244008965	minor groove reading motif; other site
1429244008966	helix-hairpin-helix signature motif; other site
1429244008967	substrate binding pocket [chemical binding]; other site
1429244008968	active site
1429244008969	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
1429244008970	Sporulation and spore germination; Region: Germane; pfam10646
1429244008971	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244008972	AMIN domain; Region: AMIN; pfam11741
1429244008973	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1429244008974	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1429244008975	active site
1429244008976	metal binding site [ion binding]; metal-binding site
1429244008977	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244008978	AMIN domain; Region: AMIN; pfam11741
1429244008979	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1429244008980	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1429244008981	active site
1429244008982	metal binding site [ion binding]; metal-binding site
1429244008983	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1429244008984	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1429244008985	substrate binding site [chemical binding]; other site
1429244008986	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1429244008987	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1429244008988	substrate binding site [chemical binding]; other site
1429244008989	ligand binding site [chemical binding]; other site
1429244008990	L-aspartate oxidase; Provisional; Region: PRK06175
1429244008991	Kelch domain; Region: Kelch; smart00612
1429244008992	Kelch motif; Region: Kelch_1; pfam01344
1429244008993	Kelch domain; Region: Kelch; smart00612
1429244008994	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
1429244008995	Kelch domain; Region: Kelch; smart00612
1429244008996	Kelch motif; Region: Kelch_1; pfam01344
1429244008997	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
1429244008998	Galactose oxidase, central domain; Region: Kelch_3; cl02701
1429244008999	SPRY domain-like in bacteria; Region: SPRY_like; cd12886
1429244009000	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1429244009001	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244009002	salt bridge; other site
1429244009003	non-specific DNA binding site [nucleotide binding]; other site
1429244009004	sequence-specific DNA binding site [nucleotide binding]; other site
1429244009005	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244009006	non-specific DNA binding site [nucleotide binding]; other site
1429244009007	salt bridge; other site
1429244009008	sequence-specific DNA binding site [nucleotide binding]; other site
1429244009009	YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function.  YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase.   Other enzymes with this fold include the peroxisomal...; Region: YdeM; cd03454
1429244009010	putative active site [active]
1429244009011	putative catalytic site [active]
1429244009012	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1429244009013	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244009014	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
1429244009015	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1429244009016	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1429244009017	[4Fe-4S] binding site [ion binding]; other site
1429244009018	molybdopterin cofactor binding site; other site
1429244009019	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1429244009020	molybdopterin cofactor binding site; other site
1429244009021	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1429244009022	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1429244009023	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
1429244009024	4Fe-4S binding domain; Region: Fer4; pfam00037
1429244009025	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
1429244009026	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
1429244009027	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1429244009028	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1429244009029	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1429244009030	Aspartase; Region: Aspartase; cd01357
1429244009031	active sites [active]
1429244009032	tetramer interface [polypeptide binding]; other site
1429244009033	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
1429244009034	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
1429244009035	G1 box; other site
1429244009036	GTP/Mg2+ binding site [chemical binding]; other site
1429244009037	Switch I region; other site
1429244009038	G2 box; other site
1429244009039	Switch II region; other site
1429244009040	G3 box; other site
1429244009041	G4 box; other site
1429244009042	G5 box; other site
1429244009043	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613
1429244009044	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244009045	FeS/SAM binding site; other site
1429244009046	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1429244009047	biotin synthase; Provisional; Region: PRK07094
1429244009048	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244009049	FeS/SAM binding site; other site
1429244009050	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1429244009051	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1429244009052	Alkaline phosphatase homologues; Region: alkPPc; smart00098
1429244009053	active site
1429244009054	dimer interface [polypeptide binding]; other site
1429244009055	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244009056	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1429244009057	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244009058	catalytic residue [active]
1429244009059	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1429244009060	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244009061	Walker A/P-loop; other site
1429244009062	ATP binding site [chemical binding]; other site
1429244009063	Q-loop/lid; other site
1429244009064	ABC transporter signature motif; other site
1429244009065	Walker B; other site
1429244009066	D-loop; other site
1429244009067	H-loop/switch region; other site
1429244009068	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1429244009069	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1429244009070	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244009071	Walker A/P-loop; other site
1429244009072	ATP binding site [chemical binding]; other site
1429244009073	Q-loop/lid; other site
1429244009074	ABC transporter signature motif; other site
1429244009075	Walker B; other site
1429244009076	D-loop; other site
1429244009077	H-loop/switch region; other site
1429244009078	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1429244009079	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244009080	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244009081	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244009082	dimer interface [polypeptide binding]; other site
1429244009083	conserved gate region; other site
1429244009084	putative PBP binding loops; other site
1429244009085	ABC-ATPase subunit interface; other site
1429244009086	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244009087	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244009088	dimer interface [polypeptide binding]; other site
1429244009089	conserved gate region; other site
1429244009090	putative PBP binding loops; other site
1429244009091	ABC-ATPase subunit interface; other site
1429244009092	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244009093	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1429244009094	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244009095	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244009096	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244009097	dimerization interface [polypeptide binding]; other site
1429244009098	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244009099	non-specific DNA binding site [nucleotide binding]; other site
1429244009100	salt bridge; other site
1429244009101	sequence-specific DNA binding site [nucleotide binding]; other site
1429244009102	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1429244009103	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583
1429244009104	putative active site [active]
1429244009105	catalytic triad [active]
1429244009106	putative dimer interface [polypeptide binding]; other site
1429244009107	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244009108	gamma-glutamyl kinase; Provisional; Region: PRK05429
1429244009109	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1429244009110	nucleotide binding site [chemical binding]; other site
1429244009111	homotetrameric interface [polypeptide binding]; other site
1429244009112	putative phosphate binding site [ion binding]; other site
1429244009113	putative allosteric binding site; other site
1429244009114	PUA domain; Region: PUA; pfam01472
1429244009115	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1429244009116	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1429244009117	putative catalytic cysteine [active]
1429244009118	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1429244009119	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1429244009120	2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Reviewed; Region: mtnW; PRK09549
1429244009121	2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Region: RLP_DK-MTP-1-P-enolase; cd08209
1429244009122	dimer interface [polypeptide binding]; other site
1429244009123	active site
1429244009124	catalytic residue [active]
1429244009125	metal binding site [ion binding]; metal-binding site
1429244009126	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1429244009127	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244009128	active site
1429244009129	motif I; other site
1429244009130	motif II; other site
1429244009131	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1429244009132	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
1429244009133	intersubunit interface [polypeptide binding]; other site
1429244009134	active site
1429244009135	Zn2+ binding site [ion binding]; other site
1429244009136	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1429244009137	RNA polymerase sigma factor SigW; Reviewed; Region: PRK09642
1429244009138	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244009139	DNA binding residues [nucleotide binding]
1429244009140	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
1429244009141	Helix-turn-helix domain; Region: HTH_36; pfam13730
1429244009142	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1429244009143	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1429244009144	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
1429244009145	putative dimer interface [polypeptide binding]; other site
1429244009146	putative anticodon binding site; other site
1429244009147	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1429244009148	homodimer interface [polypeptide binding]; other site
1429244009149	motif 1; other site
1429244009150	motif 2; other site
1429244009151	active site
1429244009152	motif 3; other site
1429244009153	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1429244009154	propionate/acetate kinase; Provisional; Region: PRK12379
1429244009155	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1429244009156	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
1429244009157	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1429244009158	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1429244009159	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244009160	Walker A motif; other site
1429244009161	ATP binding site [chemical binding]; other site
1429244009162	Walker B motif; other site
1429244009163	arginine finger; other site
1429244009164	Peptidase family M41; Region: Peptidase_M41; pfam01434
1429244009165	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
1429244009166	N-ethylammeline chlorohydrolase; Provisional; Region: PRK06038
1429244009167	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1429244009168	active site
1429244009169	putative substrate binding pocket [chemical binding]; other site
1429244009170	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1429244009171	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1429244009172	CoA binding domain; Region: CoA_binding; pfam02629
1429244009173	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
1429244009174	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1429244009175	active site
1429244009176	catalytic site [active]
1429244009177	substrate binding site [chemical binding]; other site
1429244009178	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1429244009179	ATP binding site [chemical binding]; other site
1429244009180	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244009181	putative Mg++ binding site [ion binding]; other site
1429244009182	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1429244009183	TPR repeat; Region: TPR_11; pfam13414
1429244009184	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244009185	binding surface
1429244009186	TPR motif; other site
1429244009187	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1429244009188	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1429244009189	tetramerization interface [polypeptide binding]; other site
1429244009190	active site
1429244009191	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1429244009192	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1429244009193	active site
1429244009194	ATP-binding site [chemical binding]; other site
1429244009195	pantoate-binding site; other site
1429244009196	HXXH motif; other site
1429244009197	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1429244009198	oligomerization interface [polypeptide binding]; other site
1429244009199	active site
1429244009200	metal binding site [ion binding]; metal-binding site
1429244009201	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1429244009202	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1429244009203	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1429244009204	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
1429244009205	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1429244009206	active site
1429244009207	NTP binding site [chemical binding]; other site
1429244009208	metal binding triad [ion binding]; metal-binding site
1429244009209	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1429244009210	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1429244009211	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
1429244009212	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
1429244009213	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
1429244009214	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1429244009215	active site
1429244009216	dimer interfaces [polypeptide binding]; other site
1429244009217	catalytic residues [active]
1429244009218	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1429244009219	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1429244009220	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1429244009221	TPR repeat; Region: TPR_11; pfam13414
1429244009222	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244009223	binding surface
1429244009224	TPR motif; other site
1429244009225	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1429244009226	TPR motif; other site
1429244009227	binding surface
1429244009228	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
1429244009229	homodimer interface [polypeptide binding]; other site
1429244009230	metal binding site [ion binding]; metal-binding site
1429244009231	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1429244009232	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244009233	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244009234	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1429244009235	Sporulation protein YpjB (SpoYpjB); Region: Spore_YpjB; cl09800
1429244009236	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244009237	Coenzyme A binding pocket [chemical binding]; other site
1429244009238	Protein of unknown function (DUF1405); Region: DUF1405; cl01798
1429244009239	IDEAL domain; Region: IDEAL; cl07452
1429244009240	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1429244009241	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1429244009242	trimer interface [polypeptide binding]; other site
1429244009243	putative metal binding site [ion binding]; other site
1429244009244	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1429244009245	catalytic core [active]
1429244009246	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1429244009247	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244009248	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244009249	DNA binding residues [nucleotide binding]
1429244009250	prephenate dehydrogenase; Validated; Region: PRK08507
1429244009251	prephenate dehydrogenase; Validated; Region: PRK06545
1429244009252	C-terminal ACT domain of the monofunctional, NAD dependent, prephenate dehydrogenase (PDH); Region: ACT_PDH-BS; cd04909
1429244009253	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
1429244009254	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244009255	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244009256	homodimer interface [polypeptide binding]; other site
1429244009257	catalytic residue [active]
1429244009258	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1429244009259	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1429244009260	substrate binding site [chemical binding]; other site
1429244009261	active site
1429244009262	catalytic residues [active]
1429244009263	heterodimer interface [polypeptide binding]; other site
1429244009264	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1429244009265	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1429244009266	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244009267	catalytic residue [active]
1429244009268	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1429244009269	active site
1429244009270	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1429244009271	active site
1429244009272	ribulose/triose binding site [chemical binding]; other site
1429244009273	phosphate binding site [ion binding]; other site
1429244009274	substrate (anthranilate) binding pocket [chemical binding]; other site
1429244009275	product (indole) binding pocket [chemical binding]; other site
1429244009276	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1429244009277	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1429244009278	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1429244009279	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
1429244009280	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1429244009281	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1429244009282	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
1429244009283	homotrimer interaction site [polypeptide binding]; other site
1429244009284	active site
1429244009285	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1429244009286	active site
1429244009287	dimer interface [polypeptide binding]; other site
1429244009288	metal binding site [ion binding]; metal-binding site
1429244009289	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1429244009290	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1429244009291	Tetramer interface [polypeptide binding]; other site
1429244009292	active site
1429244009293	FMN-binding site [chemical binding]; other site
1429244009294	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1429244009295	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1429244009296	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244009297	S-adenosylmethionine binding site [chemical binding]; other site
1429244009298	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1429244009299	active site
1429244009300	multimer interface [polypeptide binding]; other site
1429244009301	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1429244009302	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1429244009303	substrate binding pocket [chemical binding]; other site
1429244009304	chain length determination region; other site
1429244009305	substrate-Mg2+ binding site; other site
1429244009306	catalytic residues [active]
1429244009307	aspartate-rich region 1; other site
1429244009308	active site lid residues [active]
1429244009309	aspartate-rich region 2; other site
1429244009310	Menaquinone biosynthesis; Region: VitK2_biosynth; pfam02621
1429244009311	aromatic acid decarboxylase; Validated; Region: PRK05920
1429244009312	Flavoprotein; Region: Flavoprotein; pfam02441
1429244009313	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1429244009314	UbiA prenyltransferase family; Region: UbiA; pfam01040
1429244009315	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1429244009316	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244009317	S-adenosylmethionine binding site [chemical binding]; other site
1429244009318	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1; Region: HEPPP_synt_1; pfam07307
1429244009319	Tryptophan RNA-binding attenuator protein; Region: TrpBP; cl03437
1429244009320	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1429244009321	IHF - DNA interface [nucleotide binding]; other site
1429244009322	IHF dimer interface [polypeptide binding]; other site
1429244009323	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1429244009324	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1429244009325	Walker A/P-loop; other site
1429244009326	ATP binding site [chemical binding]; other site
1429244009327	Q-loop/lid; other site
1429244009328	ABC transporter signature motif; other site
1429244009329	Walker B; other site
1429244009330	D-loop; other site
1429244009331	H-loop/switch region; other site
1429244009332	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1429244009333	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
1429244009334	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1429244009335	putative ligand binding site [chemical binding]; other site
1429244009336	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1429244009337	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR4; cd08270
1429244009338	putative NAD(P) binding site [chemical binding]; other site
1429244009339	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1429244009340	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1429244009341	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1429244009342	stage IV sporulation protein A; Region: spore_IV_A; TIGR02836
1429244009343	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1429244009344	G1 box; other site
1429244009345	GTP/Mg2+ binding site [chemical binding]; other site
1429244009346	G2 box; other site
1429244009347	Switch I region; other site
1429244009348	G3 box; other site
1429244009349	Switch II region; other site
1429244009350	G4 box; other site
1429244009351	G5 box; other site
1429244009352	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1429244009353	catalytic loop [active]
1429244009354	iron binding site [ion binding]; other site
1429244009355	Stage VI sporulation protein F; Region: SpoVIF; pfam14069
1429244009356	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1429244009357	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1429244009358	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1429244009359	membrane protein; Provisional; Region: PRK14405
1429244009360	GTP-binding protein Der; Reviewed; Region: PRK00093
1429244009361	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1429244009362	G1 box; other site
1429244009363	GTP/Mg2+ binding site [chemical binding]; other site
1429244009364	Switch I region; other site
1429244009365	G2 box; other site
1429244009366	Switch II region; other site
1429244009367	G3 box; other site
1429244009368	G4 box; other site
1429244009369	G5 box; other site
1429244009370	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1429244009371	G1 box; other site
1429244009372	GTP/Mg2+ binding site [chemical binding]; other site
1429244009373	Switch I region; other site
1429244009374	G2 box; other site
1429244009375	G3 box; other site
1429244009376	Switch II region; other site
1429244009377	G4 box; other site
1429244009378	G5 box; other site
1429244009379	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
1429244009380	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1429244009381	RNA binding site [nucleotide binding]; other site
1429244009382	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1429244009383	RNA binding site [nucleotide binding]; other site
1429244009384	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1429244009385	RNA binding site [nucleotide binding]; other site
1429244009386	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1429244009387	RNA binding site [nucleotide binding]; other site
1429244009388	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1429244009389	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1429244009390	putative acyl-acceptor binding pocket; other site
1429244009391	cytidylate kinase; Provisional; Region: cmk; PRK00023
1429244009392	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1429244009393	CMP-binding site; other site
1429244009394	The sites determining sugar specificity; other site
1429244009395	Flagellar protein YcgR; Region: YcgR_2; pfam12945
1429244009396	PilZ domain; Region: PilZ; pfam07238
1429244009397	germination protein YpeB; Region: spore_YpeB; TIGR02889
1429244009398	Protease prsW family; Region: PrsW-protease; pfam13367
1429244009399	Negative regulator of genetic competence (MecA); Region: MecA; cl02022
1429244009400	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1429244009401	NodB motif; other site
1429244009402	active site
1429244009403	catalytic site [active]
1429244009404	metal binding site [ion binding]; metal-binding site
1429244009405	CAAX protease self-immunity; Region: Abi; pfam02517
1429244009406	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244009407	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
1429244009408	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1429244009409	ligand binding site [chemical binding]; other site
1429244009410	NAD binding site [chemical binding]; other site
1429244009411	dimerization interface [polypeptide binding]; other site
1429244009412	catalytic site [active]
1429244009413	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
1429244009414	putative L-serine binding site [chemical binding]; other site
1429244009415	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244009416	dimerization interface [polypeptide binding]; other site
1429244009417	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1429244009418	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1429244009419	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244009420	dimer interface [polypeptide binding]; other site
1429244009421	phosphorylation site [posttranslational modification]
1429244009422	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244009423	ATP binding site [chemical binding]; other site
1429244009424	Mg2+ binding site [ion binding]; other site
1429244009425	G-X-G motif; other site
1429244009426	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244009427	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244009428	active site
1429244009429	phosphorylation site [posttranslational modification]
1429244009430	intermolecular recognition site; other site
1429244009431	dimerization interface [polypeptide binding]; other site
1429244009432	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244009433	DNA binding site [nucleotide binding]
1429244009434	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1429244009435	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244009436	RNA binding surface [nucleotide binding]; other site
1429244009437	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1429244009438	active site
1429244009439	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
1429244009440	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
1429244009441	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1429244009442	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1429244009443	transglutaminase; Provisional; Region: tgl; PRK03187
1429244009444	Sporulation protein YtfJ (Spore_YtfJ); Region: Spore_YtfJ; cl01596
1429244009445	Protein of unknown function (DUF2953); Region: DUF2953; pfam11167
1429244009446	Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612
1429244009447	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
1429244009448	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1429244009449	homopentamer interface [polypeptide binding]; other site
1429244009450	active site
1429244009451	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1429244009452	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1429244009453	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1429244009454	Lumazine binding domain; Region: Lum_binding; pfam00677
1429244009455	Lumazine binding domain; Region: Lum_binding; pfam00677
1429244009456	IDEAL domain; Region: IDEAL; cl07452
1429244009457	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
1429244009458	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1429244009459	dimer interface [polypeptide binding]; other site
1429244009460	PYR/PP interface [polypeptide binding]; other site
1429244009461	TPP binding site [chemical binding]; other site
1429244009462	substrate binding site [chemical binding]; other site
1429244009463	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
1429244009464	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
1429244009465	TPP-binding site [chemical binding]; other site
1429244009466	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546
1429244009467	pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional; Region: PRK14028
1429244009468	4Fe-4S binding domain; Region: Fer4; pfam00037
1429244009469	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1429244009470	active site
1429244009471	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1429244009472	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1429244009473	active site
1429244009474	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1429244009475	substrate binding site [chemical binding]; other site
1429244009476	catalytic residues [active]
1429244009477	dimer interface [polypeptide binding]; other site
1429244009478	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244009479	Stage V sporulation protein AB; Region: SpoVAB; pfam13782
1429244009480	Stage V sporulation protein AA; Region: SporV_AA; pfam12164
1429244009481	sporulation sigma factor SigF; Validated; Region: PRK05572
1429244009482	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244009483	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1429244009484	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244009485	DNA binding residues [nucleotide binding]
1429244009486	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1429244009487	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244009488	ATP binding site [chemical binding]; other site
1429244009489	Mg2+ binding site [ion binding]; other site
1429244009490	G-X-G motif; other site
1429244009491	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1429244009492	anti sigma factor interaction site; other site
1429244009493	regulatory phosphorylation site [posttranslational modification]; other site
1429244009494	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1429244009495	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1429244009496	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1429244009497	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1429244009498	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1429244009499	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1429244009500	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1429244009501	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1429244009502	active site
1429244009503	Int/Topo IB signature motif; other site
1429244009504	Protein of unknown function (DUF4227); Region: DUF4227; pfam14004
1429244009505	ferric uptake regulator; Provisional; Region: fur; PRK09462
1429244009506	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1429244009507	metal binding site 2 [ion binding]; metal-binding site
1429244009508	putative DNA binding helix; other site
1429244009509	metal binding site 1 [ion binding]; metal-binding site
1429244009510	dimer interface [polypeptide binding]; other site
1429244009511	structural Zn2+ binding site [ion binding]; other site
1429244009512	Integral membrane protein DUF95; Region: DUF95; cl00572
1429244009513	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1429244009514	dimer interface [polypeptide binding]; other site
1429244009515	ADP-ribose binding site [chemical binding]; other site
1429244009516	active site
1429244009517	nudix motif; other site
1429244009518	metal binding site [ion binding]; metal-binding site
1429244009519	Protein of unknown function (DUF3936); Region: DUF3936; pfam13072
1429244009520	M20 Peptidase T like enzymes specifically cleave tripeptides; Region: M20_peptT_like; cd05683
1429244009521	peptidase T-like protein; Region: PepT-like; TIGR01883
1429244009522	metal binding site [ion binding]; metal-binding site
1429244009523	putative dimer interface [polypeptide binding]; other site
1429244009524	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1429244009525	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1429244009526	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1429244009527	E3 interaction surface; other site
1429244009528	lipoyl attachment site [posttranslational modification]; other site
1429244009529	e3 binding domain; Region: E3_binding; pfam02817
1429244009530	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1429244009531	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1429244009532	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1429244009533	alpha subunit interface [polypeptide binding]; other site
1429244009534	TPP binding site [chemical binding]; other site
1429244009535	heterodimer interface [polypeptide binding]; other site
1429244009536	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1429244009537	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
1429244009538	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1429244009539	tetramer interface [polypeptide binding]; other site
1429244009540	TPP-binding site [chemical binding]; other site
1429244009541	heterodimer interface [polypeptide binding]; other site
1429244009542	phosphorylation loop region [posttranslational modification]
1429244009543	dihydrolipoamide dehydrogenase; Validated; Region: PRK05976
1429244009544	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1429244009545	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244009546	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1429244009547	thymidine kinase; Provisional; Region: PRK04296
1429244009548	Sporulation control protein [General function prediction only]; Region: Spo0M; COG4326
1429244009549	SpoOM protein; Region: Spo0M; pfam07070
1429244009550	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1429244009551	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244009552	dimerization interface [polypeptide binding]; other site
1429244009553	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244009554	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244009555	dimer interface [polypeptide binding]; other site
1429244009556	putative CheW interface [polypeptide binding]; other site
1429244009557	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244009558	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244009559	S-adenosylmethionine binding site [chemical binding]; other site
1429244009560	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
1429244009561	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244009562	active site
1429244009563	phosphorylation site [posttranslational modification]
1429244009564	intermolecular recognition site; other site
1429244009565	dimerization interface [polypeptide binding]; other site
1429244009566	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
1429244009567	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1429244009568	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
1429244009569	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1429244009570	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1429244009571	Walker A/P-loop; other site
1429244009572	ATP binding site [chemical binding]; other site
1429244009573	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1429244009574	ABC transporter signature motif; other site
1429244009575	Walker B; other site
1429244009576	D-loop; other site
1429244009577	H-loop/switch region; other site
1429244009578	arginine repressor; Provisional; Region: PRK04280
1429244009579	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1429244009580	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1429244009581	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1429244009582	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244009583	RNA binding surface [nucleotide binding]; other site
1429244009584	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1429244009585	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1429244009586	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1429244009587	TPP-binding site; other site
1429244009588	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1429244009589	PYR/PP interface [polypeptide binding]; other site
1429244009590	dimer interface [polypeptide binding]; other site
1429244009591	TPP binding site [chemical binding]; other site
1429244009592	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1429244009593	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1429244009594	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1429244009595	substrate binding pocket [chemical binding]; other site
1429244009596	chain length determination region; other site
1429244009597	substrate-Mg2+ binding site; other site
1429244009598	catalytic residues [active]
1429244009599	aspartate-rich region 1; other site
1429244009600	active site lid residues [active]
1429244009601	aspartate-rich region 2; other site
1429244009602	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1429244009603	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1429244009604	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1429244009605	generic binding surface II; other site
1429244009606	generic binding surface I; other site
1429244009607	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
1429244009608	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1429244009609	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1429244009610	homodimer interface [polypeptide binding]; other site
1429244009611	NADP binding site [chemical binding]; other site
1429244009612	substrate binding site [chemical binding]; other site
1429244009613	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1429244009614	putative RNA binding site [nucleotide binding]; other site
1429244009615	Small integral membrane protein (DUF2273); Region: DUF2273; pfam10031
1429244009616	Asp23 family; Region: Asp23; cl00574
1429244009617	Asp23 family; Region: Asp23; pfam03780
1429244009618	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1429244009619	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1429244009620	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1429244009621	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1429244009622	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1429244009623	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1429244009624	carboxyltransferase (CT) interaction site; other site
1429244009625	biotinylation site [posttranslational modification]; other site
1429244009626	SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685
1429244009627	stage III sporulation protein AG; Region: spore_III_AG; TIGR02830
1429244009628	Stage III sporulation protein AF (Spore_III_AF); Region: Spore_III_AF; cl17562
1429244009629	Stage III sporulation protein AF (Spore_III_AF); Region: Spore_III_AF; cl17562
1429244009630	Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; pfam09546
1429244009631	Stage III sporulation protein AC/AD protein family; Region: SpoIIIAC; cl05961
1429244009632	Stage III sporulation protein AC/AD protein family; Region: SpoIIIAC; cl05961
1429244009633	stage III sporulation protein SpoAB; Provisional; Region: PRK08307
1429244009634	stage III sporulation protein AA; Region: spore_III_AA; TIGR02858
1429244009635	NTPase; Region: NTPase_1; cl17478
1429244009636	aspartate kinase; Reviewed; Region: PRK06635
1429244009637	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
1429244009638	putative catalytic residues [active]
1429244009639	putative nucleotide binding site [chemical binding]; other site
1429244009640	putative aspartate binding site [chemical binding]; other site
1429244009641	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1429244009642	putative allosteric regulatory site; other site
1429244009643	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1429244009644	elongation factor P; Validated; Region: PRK00529
1429244009645	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1429244009646	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1429244009647	RNA binding site [nucleotide binding]; other site
1429244009648	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1429244009649	RNA binding site [nucleotide binding]; other site
1429244009650	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1429244009651	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1429244009652	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1429244009653	active site
1429244009654	Conserved membrane protein YqhR; Region: YqhR; pfam11085
1429244009655	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244009656	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1429244009657	siderophore binding site; other site
1429244009658	Predicted metal-dependent enzyme [General function prediction only]; Region: COG3872
1429244009659	Oxygen tolerance; Region: BatD; pfam13584
1429244009660	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1429244009661	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
1429244009662	active site
1429244009663	nucleophile elbow; other site
1429244009664	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244009665	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1429244009666	manganese transport transcriptional regulator; Provisional; Region: PRK03902
1429244009667	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1429244009668	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1429244009669	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
1429244009670	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244009671	FeS/SAM binding site; other site
1429244009672	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1429244009673	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1429244009674	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1429244009675	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1429244009676	active site
1429244009677	HIGH motif; other site
1429244009678	KMSKS motif; other site
1429244009679	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1429244009680	tRNA binding surface [nucleotide binding]; other site
1429244009681	anticodon binding site; other site
1429244009682	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1429244009683	dimer interface [polypeptide binding]; other site
1429244009684	putative tRNA-binding site [nucleotide binding]; other site
1429244009685	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244009686	Haemolytic domain; Region: Haemolytic; pfam01809
1429244009687	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1429244009688	metal binding site 2 [ion binding]; metal-binding site
1429244009689	putative DNA binding helix; other site
1429244009690	metal binding site 1 [ion binding]; metal-binding site
1429244009691	dimer interface [polypeptide binding]; other site
1429244009692	structural Zn2+ binding site [ion binding]; other site
1429244009693	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244009694	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
1429244009695	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244009696	FeS/SAM binding site; other site
1429244009697	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1429244009698	Pyruvate formate lyase 1; Region: PFL1; cd01678
1429244009699	coenzyme A binding site [chemical binding]; other site
1429244009700	active site
1429244009701	catalytic residues [active]
1429244009702	glycine loop; other site
1429244009703	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1429244009704	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1429244009705	putative catalytic cysteine [active]
1429244009706	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1429244009707	putative active site [active]
1429244009708	metal binding site [ion binding]; metal-binding site
1429244009709	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1429244009710	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1429244009711	ligand binding site [chemical binding]; other site
1429244009712	flexible hinge region; other site
1429244009713	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1429244009714	putative switch regulator; other site
1429244009715	non-specific DNA interactions [nucleotide binding]; other site
1429244009716	DNA binding site [nucleotide binding]
1429244009717	sequence specific DNA binding site [nucleotide binding]; other site
1429244009718	putative cAMP binding site [chemical binding]; other site
1429244009719	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244009720	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244009721	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1429244009722	conserved cys residue [active]
1429244009723	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1429244009724	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1429244009725	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244009726	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244009727	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244009728	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1429244009729	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244009730	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244009731	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244009732	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244009733	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244009734	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244009735	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1429244009736	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1429244009737	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244009738	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244009739	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
1429244009740	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1429244009741	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1429244009742	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1429244009743	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1429244009744	SelR domain; Region: SelR; pfam01641
1429244009745	Protein of unknown function (DUF2837); Region: DUF2837; pfam10997
1429244009746	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4876
1429244009747	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1429244009748	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244009749	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244009750	EamA-like transporter family; Region: EamA; pfam00892
1429244009751	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1429244009752	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244009753	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244009754	Transglycosylase; Region: Transgly; pfam00912
1429244009755	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1429244009756	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1429244009757	DNA polymerase IV; Reviewed; Region: PRK03103
1429244009758	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1429244009759	active site
1429244009760	DNA binding site [nucleotide binding]
1429244009761	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1429244009762	Stage VI sporulation protein F; Region: SpoVIF; pfam14069
1429244009763	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1429244009764	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1429244009765	generic binding surface II; other site
1429244009766	ssDNA binding site; other site
1429244009767	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244009768	ATP binding site [chemical binding]; other site
1429244009769	putative Mg++ binding site [ion binding]; other site
1429244009770	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244009771	nucleotide binding region [chemical binding]; other site
1429244009772	ATP-binding site [chemical binding]; other site
1429244009773	EDD domain protein, DegV family; Region: DegV; TIGR00762
1429244009774	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1429244009775	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
1429244009776	DAK2 domain; Region: Dak2; pfam02734
1429244009777	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1429244009778	Stage V sporulation protein family; Region: SpoV; cl15455
1429244009779	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1429244009780	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1429244009781	substrate binding site [chemical binding]; other site
1429244009782	hexamer interface [polypeptide binding]; other site
1429244009783	metal binding site [ion binding]; metal-binding site
1429244009784	GTPase RsgA; Reviewed; Region: PRK00098
1429244009785	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1429244009786	RNA binding site [nucleotide binding]; other site
1429244009787	homodimer interface [polypeptide binding]; other site
1429244009788	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1429244009789	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1429244009790	GTP/Mg2+ binding site [chemical binding]; other site
1429244009791	G4 box; other site
1429244009792	G5 box; other site
1429244009793	G1 box; other site
1429244009794	Switch I region; other site
1429244009795	G2 box; other site
1429244009796	G3 box; other site
1429244009797	Switch II region; other site
1429244009798	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1429244009799	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1429244009800	active site
1429244009801	ATP binding site [chemical binding]; other site
1429244009802	substrate binding site [chemical binding]; other site
1429244009803	activation loop (A-loop); other site
1429244009804	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
1429244009805	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1429244009806	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1429244009807	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1429244009808	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1429244009809	active site
1429244009810	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
1429244009811	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244009812	FeS/SAM binding site; other site
1429244009813	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1429244009814	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1429244009815	putative RNA binding site [nucleotide binding]; other site
1429244009816	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244009817	S-adenosylmethionine binding site [chemical binding]; other site
1429244009818	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1429244009819	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1429244009820	putative active site [active]
1429244009821	substrate binding site [chemical binding]; other site
1429244009822	putative cosubstrate binding site; other site
1429244009823	catalytic site [active]
1429244009824	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1429244009825	substrate binding site [chemical binding]; other site
1429244009826	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1429244009827	active site
1429244009828	catalytic residues [active]
1429244009829	metal binding site [ion binding]; metal-binding site
1429244009830	primosomal protein N' Region: priA; TIGR00595
1429244009831	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244009832	ATP binding site [chemical binding]; other site
1429244009833	putative Mg++ binding site [ion binding]; other site
1429244009834	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244009835	nucleotide binding region [chemical binding]; other site
1429244009836	ATP-binding site [chemical binding]; other site
1429244009837	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1429244009838	Flavoprotein; Region: Flavoprotein; pfam02441
1429244009839	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1429244009840	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1429244009841	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1429244009842	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1429244009843	catalytic site [active]
1429244009844	G-X2-G-X-G-K; other site
1429244009845	hypothetical protein; Provisional; Region: PRK04323
1429244009846	hypothetical protein; Provisional; Region: PRK11820
1429244009847	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1429244009848	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1429244009849	bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645
1429244009850	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
1429244009851	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1429244009852	FAD binding site [chemical binding]; other site
1429244009853	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1429244009854	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1429244009855	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1429244009856	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1429244009857	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1429244009858	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1429244009859	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1429244009860	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244009861	motif II; other site
1429244009862	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1429244009863	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
1429244009864	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1429244009865	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1429244009866	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1429244009867	active site
1429244009868	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1429244009869	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; cl11453
1429244009870	Protein of unknown function (DUF964); Region: DUF964; pfam06133
1429244009871	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
1429244009872	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
1429244009873	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1429244009874	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244009875	ATP binding site [chemical binding]; other site
1429244009876	putative Mg++ binding site [ion binding]; other site
1429244009877	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244009878	nucleotide binding region [chemical binding]; other site
1429244009879	ATP-binding site [chemical binding]; other site
1429244009880	FOG: CBS domain [General function prediction only]; Region: COG0517
1429244009881	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622
1429244009882	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244009883	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1429244009884	metal binding site [ion binding]; metal-binding site
1429244009885	dimer interface [polypeptide binding]; other site
1429244009886	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1429244009887	Asp23 family; Region: Asp23; pfam03780
1429244009888	calcium/proton exchanger (cax); Region: cax; TIGR00378
1429244009889	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1429244009890	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1429244009891	hypothetical protein; Provisional; Region: PRK13666
1429244009892	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1429244009893	regulatory protein interface [polypeptide binding]; other site
1429244009894	regulatory phosphorylation site [posttranslational modification]; other site
1429244009895	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1429244009896	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1429244009897	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1429244009898	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1429244009899	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244009900	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244009901	metal binding site [ion binding]; metal-binding site
1429244009902	active site
1429244009903	I-site; other site
1429244009904	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1429244009905	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1429244009906	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244009907	RNA binding surface [nucleotide binding]; other site
1429244009908	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244009909	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244009910	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244009911	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1429244009912	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1429244009913	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1429244009914	active site
1429244009915	HIGH motif; other site
1429244009916	dimer interface [polypeptide binding]; other site
1429244009917	KMSKS motif; other site
1429244009918	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244009919	RNA binding surface [nucleotide binding]; other site
1429244009920	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244009921	Transglycosylase; Region: Transgly; pfam00912
1429244009922	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1429244009923	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1429244009924	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244009925	Interdomain contacts; other site
1429244009926	Cytokine receptor motif; other site
1429244009927	acetyl-CoA synthetase; Provisional; Region: PRK04319
1429244009928	Domain of unknown function (DUF3448); Region: DUF3448; pfam11930
1429244009929	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1429244009930	acyl-activating enzyme (AAE) consensus motif; other site
1429244009931	AMP binding site [chemical binding]; other site
1429244009932	active site
1429244009933	CoA binding site [chemical binding]; other site
1429244009934	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244009935	Coenzyme A binding pocket [chemical binding]; other site
1429244009936	catabolite control protein A; Region: ccpA; TIGR01481
1429244009937	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244009938	DNA binding site [nucleotide binding]
1429244009939	domain linker motif; other site
1429244009940	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
1429244009941	dimerization interface [polypeptide binding]; other site
1429244009942	effector binding site; other site
1429244009943	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
1429244009944	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1429244009945	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1429244009946	proposed catalytic triad [active]
1429244009947	conserved cys residue [active]
1429244009948	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1429244009949	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1429244009950	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1429244009951	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1429244009952	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1429244009953	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244009954	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244009955	active site turn [active]
1429244009956	phosphorylation site [posttranslational modification]
1429244009957	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244009958	HPr interaction site; other site
1429244009959	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244009960	active site
1429244009961	phosphorylation site [posttranslational modification]
1429244009962	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1429244009963	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1429244009964	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1429244009965	hinge; other site
1429244009966	active site
1429244009967	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1429244009968	active site residue [active]
1429244009969	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1429244009970	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1429244009971	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1429244009972	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493
1429244009973	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
1429244009974	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244009975	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244009976	putative substrate translocation pore; other site
1429244009977	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1429244009978	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1429244009979	homodimer interface [polypeptide binding]; other site
1429244009980	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244009981	catalytic residue [active]
1429244009982	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1429244009983	Protein of unknown function (DUF1292); Region: DUF1292; pfam06949
1429244009984	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1429244009985	Protein of unknown function (DUF3892); Region: DUF3892; pfam13031
1429244009986	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244009987	Small subunit of nitrite reductase (NirD) family, Rieske domain; composed of proteins similar to the Bacillus subtilis small subunit of assimilatory nitrite reductase containing a Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain...; Region: Rieske_NirD_small_Bacillus; cd03530
1429244009988	[2Fe-2S] cluster binding site [ion binding]; other site
1429244009989	NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251
1429244009990	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244009991	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1429244009992	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1429244009993	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1429244009994	ANTAR domain; Region: ANTAR; pfam03861
1429244009995	Anthranilate phosphoribosyltransferase [Amino acid transport and metabolism]; Region: TrpD; COG0547
1429244009996	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1429244009997	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1429244009998	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1429244009999	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1429244010000	[4Fe-4S] binding site [ion binding]; other site
1429244010001	molybdopterin cofactor binding site; other site
1429244010002	This CD includes formate dehydrogenases (Fdh) H and N; nitrate reductases, Nap and Nas; and other related proteins. Formate dehydrogenase H is a component of the anaerobic formate hydrogen lyase complex  and catalyzes the reversible oxidation of formate...; Region: MopB_CT_Fdh-Nap-like; cd00508
1429244010003	molybdopterin cofactor binding site; other site
1429244010004	NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251
1429244010005	Domain of unknown function (DUF4313); Region: DUF4313; pfam14190
1429244010006	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244010007	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1429244010008	PilZ domain; Region: PilZ; cl01260
1429244010009	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1429244010010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244010011	putative substrate translocation pore; other site
1429244010012	malate dehydrogenase; Provisional; Region: PRK13529
1429244010013	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1429244010014	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1429244010015	NAD(P) binding site [chemical binding]; other site
1429244010016	Membrane transport protein; Region: Mem_trans; cl09117
1429244010017	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244010018	dimerization interface [polypeptide binding]; other site
1429244010019	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244010020	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244010021	dimer interface [polypeptide binding]; other site
1429244010022	putative CheW interface [polypeptide binding]; other site
1429244010023	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
1429244010024	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1429244010025	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1429244010026	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1429244010027	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1429244010028	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244010029	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010030	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1429244010031	ABC-ATPase subunit interface; other site
1429244010032	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244010033	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244010034	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244010035	active site
1429244010036	phosphorylation site [posttranslational modification]
1429244010037	intermolecular recognition site; other site
1429244010038	dimerization interface [polypeptide binding]; other site
1429244010039	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244010040	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244010041	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244010042	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244010043	dimerization interface [polypeptide binding]; other site
1429244010044	Histidine kinase; Region: His_kinase; pfam06580
1429244010045	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244010046	ATP binding site [chemical binding]; other site
1429244010047	Mg2+ binding site [ion binding]; other site
1429244010048	G-X-G motif; other site
1429244010049	Deoxyribonuclease NucA/NucB; Region: DNase_NucA_NucB; pfam14040
1429244010050	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1429244010051	ligand binding site [chemical binding]; other site
1429244010052	active site
1429244010053	UGI interface [polypeptide binding]; other site
1429244010054	catalytic site [active]
1429244010055	S-layer homology domain; Region: SLH; pfam00395
1429244010056	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
1429244010057	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1429244010058	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1429244010059	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244010060	beta-galactosidase; Region: BGL; TIGR03356
1429244010061	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1429244010062	active site
1429244010063	P-loop; other site
1429244010064	phosphorylation site [posttranslational modification]
1429244010065	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1429244010066	methionine cluster; other site
1429244010067	active site
1429244010068	phosphorylation site [posttranslational modification]
1429244010069	metal binding site [ion binding]; metal-binding site
1429244010070	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1429244010071	HTH domain; Region: HTH_11; pfam08279
1429244010072	Mga helix-turn-helix domain; Region: Mga; pfam05043
1429244010073	PRD domain; Region: PRD; pfam00874
1429244010074	PRD domain; Region: PRD; pfam00874
1429244010075	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1429244010076	active site
1429244010077	P-loop; other site
1429244010078	phosphorylation site [posttranslational modification]
1429244010079	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244010080	active site
1429244010081	phosphorylation site [posttranslational modification]
1429244010082	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244010083	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244010084	DNA binding site [nucleotide binding]
1429244010085	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244010086	ligand binding site [chemical binding]; other site
1429244010087	dimerization interface [polypeptide binding]; other site
1429244010088	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
1429244010089	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1429244010090	substrate binding site [chemical binding]; other site
1429244010091	trimer interface [polypeptide binding]; other site
1429244010092	Mn binding site [ion binding]; other site
1429244010093	transketolase; Reviewed; Region: PRK05899
1429244010094	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1429244010095	TPP-binding site [chemical binding]; other site
1429244010096	dimer interface [polypeptide binding]; other site
1429244010097	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1429244010098	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1429244010099	PYR/PP interface [polypeptide binding]; other site
1429244010100	dimer interface [polypeptide binding]; other site
1429244010101	TPP binding site [chemical binding]; other site
1429244010102	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1429244010103	glycerol kinase; Provisional; Region: glpK; PRK00047
1429244010104	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1429244010105	N- and C-terminal domain interface [polypeptide binding]; other site
1429244010106	active site
1429244010107	MgATP binding site [chemical binding]; other site
1429244010108	catalytic site [active]
1429244010109	metal binding site [ion binding]; metal-binding site
1429244010110	glycerol binding site [chemical binding]; other site
1429244010111	homotetramer interface [polypeptide binding]; other site
1429244010112	homodimer interface [polypeptide binding]; other site
1429244010113	FBP binding site [chemical binding]; other site
1429244010114	protein IIAGlc interface [polypeptide binding]; other site
1429244010115	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244010116	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244010117	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244010118	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1429244010119	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1429244010120	dimer interface [polypeptide binding]; other site
1429244010121	anticodon binding site; other site
1429244010122	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1429244010123	homodimer interface [polypeptide binding]; other site
1429244010124	motif 1; other site
1429244010125	active site
1429244010126	motif 2; other site
1429244010127	GAD domain; Region: GAD; pfam02938
1429244010128	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1429244010129	active site
1429244010130	motif 3; other site
1429244010131	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1429244010132	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1429244010133	2-Nitropropane dioxygenase (NPD)-like domain, associated with the (acyl-carrier-protein) S-malonyltransferase  FabD. NPD is part of the nitroalkaneoxidizing enzyme family, that catalyzes oxidative denitrification of nitroalkanes to their corresponding...; Region: NPD_FabD; cd04742
1429244010134	FMN binding site [chemical binding]; other site
1429244010135	substrate binding site [chemical binding]; other site
1429244010136	putative catalytic residue [active]
1429244010137	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1429244010138	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
1429244010139	hypothetical protein; Provisional; Region: PRK06194
1429244010140	classical (c) SDRs; Region: SDR_c; cd05233
1429244010141	NAD(P) binding site [chemical binding]; other site
1429244010142	active site
1429244010143	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1429244010144	putative NADP binding site [chemical binding]; other site
1429244010145	KR domain; Region: KR; pfam08659
1429244010146	active site
1429244010147	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244010148	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1429244010149	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244010150	active site
1429244010151	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1429244010152	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1429244010153	KR domain; Region: KR; pfam08659
1429244010154	putative NADP binding site [chemical binding]; other site
1429244010155	active site
1429244010156	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244010157	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1429244010158	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244010159	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244010160	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1429244010161	active site
1429244010162	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1429244010163	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1429244010164	substrate binding site [chemical binding]; other site
1429244010165	oxyanion hole (OAH) forming residues; other site
1429244010166	trimer interface [polypeptide binding]; other site
1429244010167	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1429244010168	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244010169	active site
1429244010170	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1429244010171	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1429244010172	putative NADP binding site [chemical binding]; other site
1429244010173	KR domain; Region: KR; pfam08659
1429244010174	active site
1429244010175	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1429244010176	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1429244010177	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244010178	active site
1429244010179	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1429244010180	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1429244010181	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1429244010182	putative NADP binding site [chemical binding]; other site
1429244010183	active site
1429244010184	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1429244010185	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244010186	S-adenosylmethionine binding site [chemical binding]; other site
1429244010187	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1429244010188	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1429244010189	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1429244010190	active site
1429244010191	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1429244010192	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1429244010193	substrate binding site [chemical binding]; other site
1429244010194	oxyanion hole (OAH) forming residues; other site
1429244010195	trimer interface [polypeptide binding]; other site
1429244010196	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1429244010197	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1429244010198	substrate binding site [chemical binding]; other site
1429244010199	oxyanion hole (OAH) forming residues; other site
1429244010200	trimer interface [polypeptide binding]; other site
1429244010201	3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism]; Region: PksG; COG3425
1429244010202	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1429244010203	dimer interface [polypeptide binding]; other site
1429244010204	active site
1429244010205	polyketide beta-ketoacyl:acyl carrier protein synthase; Validated; Region: PRK07103
1429244010206	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1429244010207	dimer interface [polypeptide binding]; other site
1429244010208	active site
1429244010209	acyl carrier protein; Validated; Region: PRK07117
1429244010210	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
1429244010211	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1429244010212	Transcription antiterminator [Transcription]; Region: NusG; COG0250
1429244010213	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cd08000
1429244010214	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1429244010215	heterodimer interface [polypeptide binding]; other site
1429244010216	homodimer interface [polypeptide binding]; other site
1429244010217	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1429244010218	hypothetical protein; Provisional; Region: PRK02237
1429244010219	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
1429244010220	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1429244010221	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1429244010222	dimer interface [polypeptide binding]; other site
1429244010223	active site
1429244010224	metal binding site [ion binding]; metal-binding site
1429244010225	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244010226	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244010227	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
1429244010228	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1429244010229	dimer interface [polypeptide binding]; other site
1429244010230	active site
1429244010231	CoA binding pocket [chemical binding]; other site
1429244010232	spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869
1429244010233	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1429244010234	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1429244010235	Cupin; Region: Cupin_1; smart00835
1429244010236	Sm and related proteins; Region: Sm_like; cl00259
1429244010237	Sm1 motif; other site
1429244010238	Protein of unknown function (DUF2642); Region: DUF2642; pfam10842
1429244010239	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244010240	AMIN domain; Region: AMIN; pfam11741
1429244010241	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cd00599
1429244010242	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1429244010243	active site
1429244010244	Predicted membrane protein [Function unknown]; Region: COG2855
1429244010245	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244010246	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244010247	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1429244010248	putative dimerization interface [polypeptide binding]; other site
1429244010249	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1429244010250	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
1429244010251	inhibitor binding site; inhibition site
1429244010252	active site
1429244010253	Pectinesterase; Region: Pectinesterase; pfam01095
1429244010254	putative pectinesterase; Region: PLN02432; cl01911
1429244010255	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1429244010256	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
1429244010257	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1429244010258	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244010259	Protein of unknown function, DUF624; Region: DUF624; cl02369
1429244010260	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244010261	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010262	dimer interface [polypeptide binding]; other site
1429244010263	conserved gate region; other site
1429244010264	ABC-ATPase subunit interface; other site
1429244010265	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244010266	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010267	dimer interface [polypeptide binding]; other site
1429244010268	conserved gate region; other site
1429244010269	putative PBP binding loops; other site
1429244010270	ABC-ATPase subunit interface; other site
1429244010271	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244010272	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244010273	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244010274	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1429244010275	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244010276	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1429244010277	active site
1429244010278	catalytic triad [active]
1429244010279	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244010280	Coenzyme A binding pocket [chemical binding]; other site
1429244010281	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244010282	active site
1429244010283	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1429244010284	active site
1429244010285	dimer interface [polypeptide binding]; other site
1429244010286	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1429244010287	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1429244010288	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1429244010289	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1429244010290	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1429244010291	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1429244010292	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1429244010293	IMP binding site; other site
1429244010294	dimer interface [polypeptide binding]; other site
1429244010295	interdomain contacts; other site
1429244010296	partial ornithine binding site; other site
1429244010297	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1429244010298	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1429244010299	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1429244010300	catalytic site [active]
1429244010301	subunit interface [polypeptide binding]; other site
1429244010302	dihydroorotase; Validated; Region: pyrC; PRK09357
1429244010303	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244010304	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1429244010305	active site
1429244010306	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1429244010307	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1429244010308	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1429244010309	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1429244010310	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244010311	active site
1429244010312	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1429244010313	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244010314	RNA binding surface [nucleotide binding]; other site
1429244010315	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1429244010316	active site
1429244010317	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1429244010318	lipoprotein signal peptidase; Provisional; Region: PRK14787
1429244010319	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1429244010320	Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: IleS; COG0060
1429244010321	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1429244010322	active site
1429244010323	HIGH motif; other site
1429244010324	nucleotide binding site [chemical binding]; other site
1429244010325	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1429244010326	active site
1429244010327	KMSKS motif; other site
1429244010328	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1429244010329	tRNA binding surface [nucleotide binding]; other site
1429244010330	anticodon binding site; other site
1429244010331	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244010332	DivIVA protein; Region: DivIVA; pfam05103
1429244010333	DivIVA domain; Region: DivI1A_domain; TIGR03544
1429244010334	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
1429244010335	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1429244010336	RNA binding surface [nucleotide binding]; other site
1429244010337	YGGT family; Region: YGGT; pfam02325
1429244010338	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
1429244010339	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1429244010340	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1429244010341	catalytic residue [active]
1429244010342	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1429244010343	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1429244010344	sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888
1429244010345	sporulation sigma factor SigG; Reviewed; Region: PRK08215
1429244010346	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244010347	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1429244010348	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244010349	DNA binding residues [nucleotide binding]
1429244010350	sporulation sigma factor SigE; Reviewed; Region: PRK08301
1429244010351	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244010352	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244010353	DNA binding residues [nucleotide binding]
1429244010354	Sporulation factor SpoIIGA; Region: Peptidase_U4; pfam03419
1429244010355	sigma-E processing peptidase SpoIIGA; Region: spore_II_GA; TIGR02854
1429244010356	cell division protein FtsZ; Validated; Region: PRK09330
1429244010357	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1429244010358	nucleotide binding site [chemical binding]; other site
1429244010359	SulA interaction site; other site
1429244010360	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
1429244010361	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244010362	nucleotide binding site [chemical binding]; other site
1429244010363	SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491
1429244010364	Cell division protein FtsA; Region: FtsA; pfam14450
1429244010365	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
1429244010366	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1429244010367	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1429244010368	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1429244010369	hinge; other site
1429244010370	active site
1429244010371	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1429244010372	FAD binding domain; Region: FAD_binding_4; pfam01565
1429244010373	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1429244010374	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1429244010375	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1429244010376	active site
1429244010377	homodimer interface [polypeptide binding]; other site
1429244010378	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1429244010379	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
1429244010380	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1429244010381	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1429244010382	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1429244010383	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1429244010384	Mg++ binding site [ion binding]; other site
1429244010385	putative catalytic motif [active]
1429244010386	putative substrate binding site [chemical binding]; other site
1429244010387	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1429244010388	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1429244010389	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1429244010390	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1429244010391	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1429244010392	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1429244010393	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1429244010394	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1429244010395	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
1429244010396	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1429244010397	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1429244010398	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cd06573
1429244010399	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
1429244010400	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1429244010401	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1429244010402	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
1429244010403	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1429244010404	Cell division protein FtsL; Region: FtsL; cl11433
1429244010405	MraW methylase family; Region: Methyltransf_5; pfam01795
1429244010406	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1429244010407	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001
1429244010408	MraZ protein; Region: MraZ; pfam02381
1429244010409	MraZ protein; Region: MraZ; pfam02381
1429244010410	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1429244010411	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
1429244010412	homotetramer interface [polypeptide binding]; other site
1429244010413	ligand binding site [chemical binding]; other site
1429244010414	catalytic site [active]
1429244010415	NAD binding site [chemical binding]; other site
1429244010416	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
1429244010417	bacillithiol biosynthesis cysteine-adding enzyme BshC; Region: thiol_BshC; TIGR03998
1429244010418	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1429244010419	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244010420	Walker A/P-loop; other site
1429244010421	ATP binding site [chemical binding]; other site
1429244010422	Q-loop/lid; other site
1429244010423	ABC transporter signature motif; other site
1429244010424	Walker B; other site
1429244010425	D-loop; other site
1429244010426	H-loop/switch region; other site
1429244010427	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1429244010428	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244010429	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244010430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010431	dimer interface [polypeptide binding]; other site
1429244010432	conserved gate region; other site
1429244010433	putative PBP binding loops; other site
1429244010434	ABC-ATPase subunit interface; other site
1429244010435	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244010436	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010437	dimer interface [polypeptide binding]; other site
1429244010438	conserved gate region; other site
1429244010439	putative PBP binding loops; other site
1429244010440	ABC-ATPase subunit interface; other site
1429244010441	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1429244010442	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1429244010443	peptide binding site [polypeptide binding]; other site
1429244010444	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1429244010445	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1429244010446	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1429244010447	putative spore coat protein regulator protein YlbO; Provisional; Region: PRK13923
1429244010448	transcription factor, RsfA family; Region: DNA_bind_RsfA; TIGR02894
1429244010449	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
1429244010450	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
1429244010451	putative active site [active]
1429244010452	PhoH-like protein; Region: PhoH; pfam02562
1429244010453	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1429244010454	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1429244010455	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1429244010456	putative GEF interaction site [polypeptide binding]; other site
1429244010457	G1 box; other site
1429244010458	GTP/Mg2+ binding site [chemical binding]; other site
1429244010459	Switch I region; other site
1429244010460	G2 box; other site
1429244010461	G3 box; other site
1429244010462	Switch II region; other site
1429244010463	G4 box; other site
1429244010464	G5 box; other site
1429244010465	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1429244010466	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1429244010467	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
1429244010468	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
1429244010469	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
1429244010470	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1429244010471	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1429244010472	Ligand Binding Site [chemical binding]; other site
1429244010473	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1429244010474	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1429244010475	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244010476	catalytic residue [active]
1429244010477	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1429244010478	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1429244010479	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1429244010480	catalytic residue [active]
1429244010481	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
1429244010482	Protein of unknown function (DUF3907); Region: DUF3907; pfam13047
1429244010483	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
1429244010484	type VII secretion-associated serine protease mycosin; Region: T7SS_mycosin; TIGR03921
1429244010485	active site
1429244010486	catalytic triad [active]
1429244010487	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1429244010488	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244010489	DNA-binding site [nucleotide binding]; DNA binding site
1429244010490	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244010491	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244010492	homodimer interface [polypeptide binding]; other site
1429244010493	catalytic residue [active]
1429244010494	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1429244010495	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244010496	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244010497	homodimer interface [polypeptide binding]; other site
1429244010498	catalytic residue [active]
1429244010499	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1429244010500	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1429244010501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1429244010502	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1429244010503	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1429244010504	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
1429244010505	Family of unknown function (DUF633); Region: DUF633; pfam04816
1429244010506	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
1429244010507	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
1429244010508	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1429244010509	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1429244010510	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244010511	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1429244010512	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244010513	DNA binding residues [nucleotide binding]
1429244010514	DNA primase; Validated; Region: dnaG; PRK05667
1429244010515	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1429244010516	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1429244010517	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1429244010518	active site
1429244010519	metal binding site [ion binding]; metal-binding site
1429244010520	interdomain interaction site; other site
1429244010521	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1429244010522	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
1429244010523	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1429244010524	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1429244010525	dimer interface [polypeptide binding]; other site
1429244010526	motif 1; other site
1429244010527	active site
1429244010528	motif 2; other site
1429244010529	motif 3; other site
1429244010530	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244010531	Recombination protein O N terminal; Region: RecO_N; pfam11967
1429244010532	DNA repair protein RecO; Region: reco; TIGR00613
1429244010533	Recombination protein O C terminal; Region: RecO_C; pfam02565
1429244010534	YqzL-like protein; Region: YqzL; pfam14006
1429244010535	GTPase Era; Reviewed; Region: era; PRK00089
1429244010536	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1429244010537	G1 box; other site
1429244010538	GTP/Mg2+ binding site [chemical binding]; other site
1429244010539	Switch I region; other site
1429244010540	G2 box; other site
1429244010541	Switch II region; other site
1429244010542	G3 box; other site
1429244010543	G4 box; other site
1429244010544	G5 box; other site
1429244010545	KH domain; Region: KH_2; pfam07650
1429244010546	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
1429244010547	metal-binding heat shock protein; Provisional; Region: PRK00016
1429244010548	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
1429244010549	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244010550	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244010551	Zn2+ binding site [ion binding]; other site
1429244010552	Mg2+ binding site [ion binding]; other site
1429244010553	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1429244010554	PhoH-like protein; Region: PhoH; pfam02562
1429244010555	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
1429244010556	Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898
1429244010557	YabP family; Region: YabP; cl06766
1429244010558	amino acid transporter; Region: 2A0306; TIGR00909
1429244010559	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1429244010560	hypothetical protein; Provisional; Region: PRK13665
1429244010561	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
1429244010562	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_like; cd07021
1429244010563	dimer interface [polypeptide binding]; other site
1429244010564	active site residues [active]
1429244010565	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
1429244010566	Yqey-like protein; Region: YqeY; pfam09424
1429244010567	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1429244010568	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1429244010569	nucleotide binding site/active site [active]
1429244010570	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1429244010571	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244010572	DNA-binding site [nucleotide binding]; DNA binding site
1429244010573	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244010574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244010575	homodimer interface [polypeptide binding]; other site
1429244010576	catalytic residue [active]
1429244010577	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1429244010578	AAA domain; Region: AAA_23; pfam13476
1429244010579	Walker A/P-loop; other site
1429244010580	ATP binding site [chemical binding]; other site
1429244010581	Q-loop/lid; other site
1429244010582	ABC transporter signature motif; other site
1429244010583	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1429244010584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244010585	ABC transporter signature motif; other site
1429244010586	Walker B; other site
1429244010587	D-loop; other site
1429244010588	H-loop/switch region; other site
1429244010589	exonuclease subunit SbcD; Provisional; Region: PRK10966
1429244010590	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1429244010591	active site
1429244010592	metal binding site [ion binding]; metal-binding site
1429244010593	DNA binding site [nucleotide binding]
1429244010594	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1429244010595	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1429244010596	Part of AAA domain; Region: AAA_19; pfam13245
1429244010597	Family description; Region: UvrD_C_2; pfam13538
1429244010598	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1429244010599	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1429244010600	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1429244010601	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1429244010602	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1429244010603	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1429244010604	putative RNA binding site [nucleotide binding]; other site
1429244010605	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244010606	S-adenosylmethionine binding site [chemical binding]; other site
1429244010607	Na/Pi-cotransporter; Region: NaPi_cotrn_rel; TIGR00704
1429244010608	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1429244010609	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1429244010610	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
1429244010611	active site
1429244010612	Ap6A binding site [chemical binding]; other site
1429244010613	nudix motif; other site
1429244010614	metal binding site [ion binding]; metal-binding site
1429244010615	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1429244010616	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1429244010617	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244010618	FeS/SAM binding site; other site
1429244010619	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1429244010620	RNA methyltransferase, RsmE family; Region: TIGR00046
1429244010621	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1429244010622	Peptidase family M50; Region: Peptidase_M50; pfam02163
1429244010623	active site
1429244010624	putative substrate binding region [chemical binding]; other site
1429244010625	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1429244010626	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244010627	S-adenosylmethionine binding site [chemical binding]; other site
1429244010628	YfhD-like protein; Region: YfhD; pfam14151
1429244010629	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1429244010630	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1429244010631	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244010632	active site
1429244010633	phosphorylation site [posttranslational modification]
1429244010634	intermolecular recognition site; other site
1429244010635	dimerization interface [polypeptide binding]; other site
1429244010636	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1429244010637	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244010638	ATP binding site [chemical binding]; other site
1429244010639	Mg2+ binding site [ion binding]; other site
1429244010640	G-X-G motif; other site
1429244010641	chaperone protein DnaJ; Provisional; Region: PRK14280
1429244010642	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1429244010643	HSP70 interaction site [polypeptide binding]; other site
1429244010644	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1429244010645	substrate binding site [polypeptide binding]; other site
1429244010646	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1429244010647	Zn binding sites [ion binding]; other site
1429244010648	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1429244010649	dimer interface [polypeptide binding]; other site
1429244010650	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1429244010651	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1429244010652	nucleotide binding site [chemical binding]; other site
1429244010653	NEF interaction site [polypeptide binding]; other site
1429244010654	SBD interface [polypeptide binding]; other site
1429244010655	GrpE; Region: GrpE; pfam01025
1429244010656	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1429244010657	dimer interface [polypeptide binding]; other site
1429244010658	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1429244010659	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1429244010660	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
1429244010661	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244010662	Coenzyme A binding pocket [chemical binding]; other site
1429244010663	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1429244010664	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244010665	FeS/SAM binding site; other site
1429244010666	HemN C-terminal domain; Region: HemN_C; pfam06969
1429244010667	GTP-binding protein LepA; Provisional; Region: PRK05433
1429244010668	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1429244010669	G1 box; other site
1429244010670	putative GEF interaction site [polypeptide binding]; other site
1429244010671	GTP/Mg2+ binding site [chemical binding]; other site
1429244010672	Switch I region; other site
1429244010673	G2 box; other site
1429244010674	G3 box; other site
1429244010675	Switch II region; other site
1429244010676	G4 box; other site
1429244010677	G5 box; other site
1429244010678	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1429244010679	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1429244010680	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1429244010681	Stage II sporulation protein P (SpoIIP); Region: SpoIIP; pfam07454
1429244010682	stage II sporulation protein P; Region: spore_II_P; TIGR02867
1429244010683	germination protease; Provisional; Region: PRK02858
1429244010684	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1429244010685	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1429244010686	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1429244010687	Putative zinc-finger; Region: zf-HC2; pfam13490
1429244010688	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1429244010689	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244010690	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244010691	DNA binding residues [nucleotide binding]
1429244010692	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244010693	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244010694	intersubunit interface [polypeptide binding]; other site
1429244010695	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1429244010696	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1429244010697	Competence protein; Region: Competence; pfam03772
1429244010698	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1429244010699	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1429244010700	catalytic motif [active]
1429244010701	Zn binding site [ion binding]; other site
1429244010702	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1429244010703	Helix-hairpin-helix motif; Region: HHH; pfam00633
1429244010704	late competence protein ComER; Validated; Region: PRK07680
1429244010705	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1429244010706	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1429244010707	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1429244010708	HIGH motif; other site
1429244010709	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1429244010710	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1429244010711	active site
1429244010712	KMSKS motif; other site
1429244010713	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1429244010714	tRNA binding surface [nucleotide binding]; other site
1429244010715	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244010716	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cl01268
1429244010717	trimer interface [polypeptide binding]; other site
1429244010718	putative substrate binding pocket [chemical binding]; other site
1429244010719	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1429244010720	active site 1 [active]
1429244010721	dimer interface [polypeptide binding]; other site
1429244010722	hexamer interface [polypeptide binding]; other site
1429244010723	active site 2 [active]
1429244010724	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1429244010725	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244010726	S-adenosylmethionine binding site [chemical binding]; other site
1429244010727	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1429244010728	S1 domain; Region: S1_2; pfam13509
1429244010729	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1429244010730	RNA binding site [nucleotide binding]; other site
1429244010731	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
1429244010732	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244010733	Zn2+ binding site [ion binding]; other site
1429244010734	Mg2+ binding site [ion binding]; other site
1429244010735	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1429244010736	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1429244010737	active site
1429244010738	(T/H)XGH motif; other site
1429244010739	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
1429244010740	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1429244010741	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1429244010742	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1429244010743	shikimate binding site; other site
1429244010744	NAD(P) binding site [chemical binding]; other site
1429244010745	GTPase YqeH; Provisional; Region: PRK13796
1429244010746	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
1429244010747	GTP/Mg2+ binding site [chemical binding]; other site
1429244010748	G4 box; other site
1429244010749	G5 box; other site
1429244010750	G1 box; other site
1429244010751	Switch I region; other site
1429244010752	G2 box; other site
1429244010753	G3 box; other site
1429244010754	Switch II region; other site
1429244010755	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
1429244010756	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244010757	active site
1429244010758	motif I; other site
1429244010759	motif II; other site
1429244010760	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1429244010761	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1429244010762	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
1429244010763	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1429244010764	Protein of unknown function DUF58; Region: DUF58; pfam01882
1429244010765	MoxR-like ATPases [General function prediction only]; Region: COG0714
1429244010766	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244010767	Walker A motif; other site
1429244010768	ATP binding site [chemical binding]; other site
1429244010769	Walker B motif; other site
1429244010770	arginine finger; other site
1429244010771	stage V sporulation protein AE; Region: spore_V_AE; TIGR02839
1429244010772	stage V sporulation protein AD; Validated; Region: PRK08304
1429244010773	stage V sporulation protein AD; Provisional; Region: PRK12404
1429244010774	SpoVA protein; Region: SpoVA; cl04298
1429244010775	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1429244010776	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1429244010777	oligomer interface [polypeptide binding]; other site
1429244010778	active site
1429244010779	metal binding site [ion binding]; metal-binding site
1429244010780	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1429244010781	Endoglucanase C-terminal domain/subunit and related proteins [Carbohydrate transport and metabolism]; Region: COG4305
1429244010782	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1429244010783	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244010784	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244010785	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244010786	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
1429244010787	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244010788	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010789	dimer interface [polypeptide binding]; other site
1429244010790	conserved gate region; other site
1429244010791	putative PBP binding loops; other site
1429244010792	ABC-ATPase subunit interface; other site
1429244010793	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244010794	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010795	dimer interface [polypeptide binding]; other site
1429244010796	conserved gate region; other site
1429244010797	ABC-ATPase subunit interface; other site
1429244010798	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1429244010799	extended (e) SDRs; Region: SDR_e; cd08946
1429244010800	NAD(P) binding site [chemical binding]; other site
1429244010801	active site
1429244010802	substrate binding site [chemical binding]; other site
1429244010803	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1429244010804	EamA-like transporter family; Region: EamA; pfam00892
1429244010805	EamA-like transporter family; Region: EamA; pfam00892
1429244010806	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1429244010807	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1429244010808	putative active site [active]
1429244010809	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1429244010810	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244010811	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244010812	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH; cl00942
1429244010813	DCoH dimer interaction site [polypeptide binding]; other site
1429244010814	aromatic arch; other site
1429244010815	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
1429244010816	DCoH tetramer interaction site [polypeptide binding]; other site
1429244010817	substrate binding site [chemical binding]; other site
1429244010818	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1429244010819	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1429244010820	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244010821	sporulation sigma factor SigK; Reviewed; Region: PRK05803
1429244010822	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244010823	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244010824	DNA binding residues [nucleotide binding]
1429244010825	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1429244010826	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244010827	Interdomain contacts; other site
1429244010828	Cytokine receptor motif; other site
1429244010829	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244010830	Interdomain contacts; other site
1429244010831	Cytokine receptor motif; other site
1429244010832	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244010833	Interdomain contacts; other site
1429244010834	Cytokine receptor motif; other site
1429244010835	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244010836	Interdomain contacts; other site
1429244010837	Cytokine receptor motif; other site
1429244010838	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244010839	Interdomain contacts; other site
1429244010840	Cytokine receptor motif; other site
1429244010841	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244010842	Interdomain contacts; other site
1429244010843	Cytokine receptor motif; other site
1429244010844	S-layer homology domain; Region: SLH; pfam00395
1429244010845	S-layer homology domain; Region: SLH; pfam00395
1429244010846	S-layer homology domain; Region: SLH; pfam00395
1429244010847	MG2 domain; Region: A2M_N; pfam01835
1429244010848	MG2 domain; Region: A2M_N; pfam01835
1429244010849	AAA domain; Region: AAA_33; pfam13671
1429244010850	hypothetical protein; Provisional; Region: PRK06762
1429244010851	Domain of unknown function (DUF4395); Region: DUF4395; pfam14340
1429244010852	Uncharacterized conserved protein (DUF2294); Region: DUF2294; cl02390
1429244010853	MarR family; Region: MarR_2; cl17246
1429244010854	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244010855	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1429244010856	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244010857	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244010858	active site
1429244010859	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1429244010860	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010861	dimer interface [polypeptide binding]; other site
1429244010862	ABC-ATPase subunit interface; other site
1429244010863	putative PBP binding loops; other site
1429244010864	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1429244010865	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1429244010866	thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688
1429244010867	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1429244010868	ATP binding site [chemical binding]; other site
1429244010869	substrate interface [chemical binding]; other site
1429244010870	Ubiquitin-like proteins; Region: UBQ; cl00155
1429244010871	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1429244010872	MoaE homodimer interface [polypeptide binding]; other site
1429244010873	MoaD interaction [polypeptide binding]; other site
1429244010874	active site residues [active]
1429244010875	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1429244010876	MoaE interaction surface [polypeptide binding]; other site
1429244010877	MoeB interaction surface [polypeptide binding]; other site
1429244010878	thiocarboxylated glycine; other site
1429244010879	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1429244010880	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1429244010881	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244010882	FeS/SAM binding site; other site
1429244010883	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1429244010884	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1429244010885	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1429244010886	catalytic loop [active]
1429244010887	iron binding site [ion binding]; other site
1429244010888	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1429244010889	4Fe-4S binding domain; Region: Fer4; pfam00037
1429244010890	4Fe-4S binding domain; Region: Fer4; pfam00037
1429244010891	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1429244010892	[4Fe-4S] binding site [ion binding]; other site
1429244010893	molybdopterin cofactor binding site; other site
1429244010894	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1429244010895	molybdopterin cofactor binding site; other site
1429244010896	Uncharacterized conserved protein [Function unknown]; Region: COG2427
1429244010897	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
1429244010898	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1429244010899	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244010900	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244010901	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244010902	dimerization interface [polypeptide binding]; other site
1429244010903	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244010904	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244010905	dimer interface [polypeptide binding]; other site
1429244010906	putative CheW interface [polypeptide binding]; other site
1429244010907	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1429244010908	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1429244010909	ligand binding site [chemical binding]; other site
1429244010910	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1429244010911	Cytochrome P450; Region: p450; pfam00067
1429244010912	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
1429244010913	Flavodoxin; Region: Flavodoxin_1; pfam00258
1429244010914	These bifunctional proteins fuse N-terminal cytochrome p450 with a cytochrome p450 reductase (CYPOR). NADPH cytochrome p450 reductase serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine...; Region: bifunctional_CYPOR; cd06206
1429244010915	FAD binding pocket [chemical binding]; other site
1429244010916	FAD binding motif [chemical binding]; other site
1429244010917	catalytic residues [active]
1429244010918	NAD binding pocket [chemical binding]; other site
1429244010919	phosphate binding motif [ion binding]; other site
1429244010920	beta-alpha-beta structure motif; other site
1429244010921	Restriction endonuclease; Region: Mrr_cat; pfam04471
1429244010922	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1429244010923	Aspartase; Region: Aspartase; cd01357
1429244010924	active sites [active]
1429244010925	tetramer interface [polypeptide binding]; other site
1429244010926	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1429244010927	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244010928	Coenzyme A binding pocket [chemical binding]; other site
1429244010929	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
1429244010930	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244010931	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
1429244010932	generic binding surface I; other site
1429244010933	generic binding surface II; other site
1429244010934	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
1429244010935	putative active site [active]
1429244010936	putative catalytic site [active]
1429244010937	putative Mg binding site IVb [ion binding]; other site
1429244010938	putative phosphate binding site [ion binding]; other site
1429244010939	putative DNA binding site [nucleotide binding]; other site
1429244010940	putative Mg binding site IVa [ion binding]; other site
1429244010941	S-layer homology domain; Region: SLH; pfam00395
1429244010942	S-layer homology domain; Region: SLH; pfam00395
1429244010943	aminotransferase A; Validated; Region: PRK07683
1429244010944	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244010945	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244010946	homodimer interface [polypeptide binding]; other site
1429244010947	catalytic residue [active]
1429244010948	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1429244010949	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244010950	H-loop/switch region; other site
1429244010951	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1429244010952	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1429244010953	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010954	dimer interface [polypeptide binding]; other site
1429244010955	conserved gate region; other site
1429244010956	putative PBP binding loops; other site
1429244010957	ABC-ATPase subunit interface; other site
1429244010958	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244010959	dimer interface [polypeptide binding]; other site
1429244010960	ABC-ATPase subunit interface; other site
1429244010961	putative PBP binding loops; other site
1429244010962	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1429244010963	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244010964	Walker A/P-loop; other site
1429244010965	ATP binding site [chemical binding]; other site
1429244010966	Q-loop/lid; other site
1429244010967	ABC transporter signature motif; other site
1429244010968	Walker B; other site
1429244010969	D-loop; other site
1429244010970	H-loop/switch region; other site
1429244010971	TOBE domain; Region: TOBE_2; pfam08402
1429244010972	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
1429244010973	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244010974	metal binding site [ion binding]; metal-binding site
1429244010975	putative dimer interface [polypeptide binding]; other site
1429244010976	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
1429244010977	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
1429244010978	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1429244010979	trimer interface [polypeptide binding]; other site
1429244010980	active site
1429244010981	substrate binding site [chemical binding]; other site
1429244010982	CoA binding site [chemical binding]; other site
1429244010983	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1429244010984	EamA-like transporter family; Region: EamA; pfam00892
1429244010985	EamA-like transporter family; Region: EamA; pfam00892
1429244010986	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1429244010987	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1429244010988	active site residue [active]
1429244010989	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1429244010990	active site residue [active]
1429244010991	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244010992	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244010993	S-adenosylmethionine binding site [chemical binding]; other site
1429244010994	DinB superfamily; Region: DinB_2; pfam12867
1429244010995	Mycothiol maleylpyruvate isomerase N-terminal domain; Region: MDMPI_N; pfam11716
1429244010996	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244010997	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244010998	Coenzyme A binding pocket [chemical binding]; other site
1429244010999	Helix-turn-helix domain; Region: HTH_17; pfam12728
1429244011000	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244011001	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1429244011002	Coenzyme A binding pocket [chemical binding]; other site
1429244011003	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244011004	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1429244011005	Coenzyme A binding pocket [chemical binding]; other site
1429244011006	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1429244011007	non-specific DNA binding site [nucleotide binding]; other site
1429244011008	salt bridge; other site
1429244011009	sequence-specific DNA binding site [nucleotide binding]; other site
1429244011010	Protein of unknown function (DUF3782); Region: DUF3782; pfam12644
1429244011011	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1429244011012	non-specific DNA binding site [nucleotide binding]; other site
1429244011013	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1429244011014	salt bridge; other site
1429244011015	sequence-specific DNA binding site [nucleotide binding]; other site
1429244011016	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1429244011017	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
1429244011018	putative active site [active]
1429244011019	putative NTP binding site [chemical binding]; other site
1429244011020	putative nucleic acid binding site [nucleotide binding]; other site
1429244011021	Cache domain; Region: Cache_1; pfam02743
1429244011022	HAMP domain; Region: HAMP; pfam00672
1429244011023	dimerization interface [polypeptide binding]; other site
1429244011024	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244011025	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244011026	dimer interface [polypeptide binding]; other site
1429244011027	putative CheW interface [polypeptide binding]; other site
1429244011028	Astacin (Peptidase family M12A); Region: Astacin; pfam01400
1429244011029	Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to...; Region: ZnMc_astacin_like; cd04280
1429244011030	active site
1429244011031	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1429244011032	catalytic core [active]
1429244011033	Endoribonuclease XendoU; Region: XendoU; pfam09412
1429244011034	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1429244011035	Peptidase S8 family domain in CspA-like proteins; Region: Peptidases_S8_CspA-like; cd07478
1429244011036	active site
1429244011037	catalytic triad [active]
1429244011038	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244011039	Coenzyme A binding pocket [chemical binding]; other site
1429244011040	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1429244011041	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1429244011042	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1429244011043	urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425
1429244011044	allophanate hydrolase; Provisional; Region: PRK08186
1429244011045	Amidase; Region: Amidase; cl11426
1429244011046	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1429244011047	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1429244011048	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1429244011049	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1429244011050	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244011051	dimer interface [polypeptide binding]; other site
1429244011052	conserved gate region; other site
1429244011053	putative PBP binding loops; other site
1429244011054	ABC-ATPase subunit interface; other site
1429244011055	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1429244011056	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1429244011057	Walker A/P-loop; other site
1429244011058	ATP binding site [chemical binding]; other site
1429244011059	Q-loop/lid; other site
1429244011060	ABC transporter signature motif; other site
1429244011061	Walker B; other site
1429244011062	D-loop; other site
1429244011063	H-loop/switch region; other site
1429244011064	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1429244011065	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1429244011066	NMT1/THI5 like; Region: NMT1; pfam09084
1429244011067	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
1429244011068	Isochorismatase family; Region: Isochorismatase; pfam00857
1429244011069	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1429244011070	catalytic triad [active]
1429244011071	conserved cis-peptide bond; other site
1429244011072	Isochorismatase family; Region: Isochorismatase; pfam00857
1429244011073	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1429244011074	catalytic triad [active]
1429244011075	conserved cis-peptide bond; other site
1429244011076	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1429244011077	amidohydrolase; Region: amidohydrolases; TIGR01891
1429244011078	putative metal binding site [ion binding]; other site
1429244011079	Predicted transcriptional regulator [Transcription]; Region: COG2345
1429244011080	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244011081	Coenzyme A binding pocket [chemical binding]; other site
1429244011082	Protein of unknown function (DUF1697); Region: DUF1697; cl01557
1429244011083	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1429244011084	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1429244011085	substrate binding pocket [chemical binding]; other site
1429244011086	chain length determination region; other site
1429244011087	substrate-Mg2+ binding site; other site
1429244011088	catalytic residues [active]
1429244011089	aspartate-rich region 1; other site
1429244011090	active site lid residues [active]
1429244011091	aspartate-rich region 2; other site
1429244011092	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
1429244011093	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
1429244011094	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1429244011095	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244011096	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244011097	dimer interface [polypeptide binding]; other site
1429244011098	putative CheW interface [polypeptide binding]; other site
1429244011099	Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545
1429244011100	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1429244011101	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244011102	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011103	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011104	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244011105	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244011106	intersubunit interface [polypeptide binding]; other site
1429244011107	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1429244011108	Protein of unknown function DUF2625; Region: DUF2625; cl08177
1429244011109	Phosphotransferase enzyme family; Region: APH; pfam01636
1429244011110	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1429244011111	active site
1429244011112	ATP binding site [chemical binding]; other site
1429244011113	substrate binding site [chemical binding]; other site
1429244011114	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244011115	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244011116	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244011117	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244011118	putative substrate translocation pore; other site
1429244011119	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
1429244011120	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1429244011121	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1429244011122	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244011123	Walker A/P-loop; other site
1429244011124	ATP binding site [chemical binding]; other site
1429244011125	Q-loop/lid; other site
1429244011126	ABC transporter signature motif; other site
1429244011127	Walker B; other site
1429244011128	D-loop; other site
1429244011129	H-loop/switch region; other site
1429244011130	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244011131	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244011132	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244011133	Walker A/P-loop; other site
1429244011134	ATP binding site [chemical binding]; other site
1429244011135	Q-loop/lid; other site
1429244011136	ABC transporter signature motif; other site
1429244011137	Walker B; other site
1429244011138	D-loop; other site
1429244011139	H-loop/switch region; other site
1429244011140	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244011141	Protein of unknown function (DUF1177); Region: DUF1177; pfam06675
1429244011142	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08651
1429244011143	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1429244011144	metal binding site [ion binding]; metal-binding site
1429244011145	dimer interface [polypeptide binding]; other site
1429244011146	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244011147	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1429244011148	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244011149	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244011150	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244011151	dimer interface [polypeptide binding]; other site
1429244011152	conserved gate region; other site
1429244011153	putative PBP binding loops; other site
1429244011154	ABC-ATPase subunit interface; other site
1429244011155	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244011156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244011157	dimer interface [polypeptide binding]; other site
1429244011158	conserved gate region; other site
1429244011159	putative PBP binding loops; other site
1429244011160	ABC-ATPase subunit interface; other site
1429244011161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244011162	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244011163	putative substrate translocation pore; other site
1429244011164	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244011165	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011166	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244011167	PAS domain; Region: PAS_9; pfam13426
1429244011168	putative active site [active]
1429244011169	heme pocket [chemical binding]; other site
1429244011170	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244011171	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244011172	metal binding site [ion binding]; metal-binding site
1429244011173	active site
1429244011174	I-site; other site
1429244011175	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244011176	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1429244011177	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244011178	SnoaL-like domain; Region: SnoaL_2; pfam12680
1429244011179	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1429244011180	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244011181	dimer interface [polypeptide binding]; other site
1429244011182	putative CheW interface [polypeptide binding]; other site
1429244011183	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1429244011184	beta-galactosidase; Region: BGL; TIGR03356
1429244011185	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244011186	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244011187	PRD domain; Region: PRD; pfam00874
1429244011188	PRD domain; Region: PRD; pfam00874
1429244011189	molybdenum cofactor biosynthesis protein A, bacterial; Region: moaA; TIGR02666
1429244011190	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244011191	FeS/SAM binding site; other site
1429244011192	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1429244011193	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1429244011194	MoaE interaction surface [polypeptide binding]; other site
1429244011195	MoeB interaction surface [polypeptide binding]; other site
1429244011196	thiocarboxylated glycine; other site
1429244011197	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1429244011198	MoaE homodimer interface [polypeptide binding]; other site
1429244011199	MoaD interaction [polypeptide binding]; other site
1429244011200	active site residues [active]
1429244011201	thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688
1429244011202	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1429244011203	ATP binding site [chemical binding]; other site
1429244011204	substrate interface [chemical binding]; other site
1429244011205	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1429244011206	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244011207	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244011208	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244011209	active site
1429244011210	phosphorylation site [posttranslational modification]
1429244011211	intermolecular recognition site; other site
1429244011212	dimerization interface [polypeptide binding]; other site
1429244011213	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244011214	DNA binding residues [nucleotide binding]
1429244011215	dimerization interface [polypeptide binding]; other site
1429244011216	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1429244011217	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1429244011218	Histidine kinase; Region: HisKA_3; pfam07730
1429244011219	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244011220	ATP binding site [chemical binding]; other site
1429244011221	Mg2+ binding site [ion binding]; other site
1429244011222	G-X-G motif; other site
1429244011223	GAF domain; Region: GAF_3; pfam13492
1429244011224	Nitrate reductase gamma subunit; Region: Nitrate_red_gam; pfam02665
1429244011225	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1429244011226	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1429244011227	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1429244011228	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1429244011229	[4Fe-4S] binding site [ion binding]; other site
1429244011230	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1429244011231	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1429244011232	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1429244011233	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1429244011234	molybdopterin cofactor binding site; other site
1429244011235	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1429244011236	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244011237	putative PBP binding loops; other site
1429244011238	ABC-ATPase subunit interface; other site
1429244011239	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1429244011240	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1429244011241	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
1429244011242	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1429244011243	Hemerythrin-like domain; Region: Hr-like; cd12108
1429244011244	Fe binding site [ion binding]; other site
1429244011245	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
1429244011246	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1429244011247	radical SAM protein, BA_1875 family; Region: sam_11; TIGR04053
1429244011248	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244011249	FeS/SAM binding site; other site
1429244011250	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1429244011251	YwiC-like protein; Region: YwiC; pfam14256
1429244011252	Domain of unknown function (DUF1963); Region: DUF1963; pfam09234
1429244011253	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1429244011254	FtsZ protein binding site [polypeptide binding]; other site
1429244011255	phosphatidylinositol phosphate kinase; Provisional; Region: PLN03185
1429244011256	WXG100 family type VII secretion target; Region: WXG100_ESAT6; TIGR03930
1429244011257	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1429244011258	transaminase; Reviewed; Region: PRK08068
1429244011259	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244011260	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244011261	homodimer interface [polypeptide binding]; other site
1429244011262	catalytic residue [active]
1429244011263	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1429244011264	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1429244011265	Protein of unknown function (DUF1541); Region: DUF1541; pfam07563
1429244011266	Protein of unknown function (DUF1541); Region: DUF1541; pfam07563
1429244011267	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244011268	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244011269	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1429244011270	metal ion-dependent adhesion site (MIDAS); other site
1429244011271	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
1429244011272	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
1429244011273	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1429244011274	DNA binding site [nucleotide binding]
1429244011275	active site
1429244011276	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1429244011277	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1429244011278	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011279	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011280	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1429244011281	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1429244011282	tetramer interface [polypeptide binding]; other site
1429244011283	active site
1429244011284	Mg2+/Mn2+ binding site [ion binding]; other site
1429244011285	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1429244011286	catalytic residue [active]
1429244011287	Predicted acetyltransferase [General function prediction only]; Region: COG3393
1429244011288	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244011289	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244011290	putative substrate translocation pore; other site
1429244011291	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244011292	putative DNA binding site [nucleotide binding]; other site
1429244011293	dimerization interface [polypeptide binding]; other site
1429244011294	putative Zn2+ binding site [ion binding]; other site
1429244011295	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1429244011296	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244011297	NAD(P) binding site [chemical binding]; other site
1429244011298	active site
1429244011299	Agrobacterium tumefaciens protein Atu4866; Region: Atu4866; pfam11512
1429244011300	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1429244011301	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011302	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244011303	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244011304	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244011305	DNA binding site [nucleotide binding]
1429244011306	domain linker motif; other site
1429244011307	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244011308	ligand binding site [chemical binding]; other site
1429244011309	dimerization interface [polypeptide binding]; other site
1429244011310	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1429244011311	(2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233
1429244011312	putative NAD(P) binding site [chemical binding]; other site
1429244011313	catalytic Zn binding site [ion binding]; other site
1429244011314	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244011315	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011316	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011317	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1429244011318	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
1429244011319	putative ligand binding residues [chemical binding]; other site
1429244011320	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1429244011321	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1429244011322	putative metal binding site [ion binding]; other site
1429244011323	VanZ like family; Region: VanZ; pfam04892
1429244011324	RDD family; Region: RDD; pfam06271
1429244011325	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1429244011326	dimer interface [polypeptide binding]; other site
1429244011327	FMN binding site [chemical binding]; other site
1429244011328	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1429244011329	active site 1 [active]
1429244011330	dimer interface [polypeptide binding]; other site
1429244011331	hexamer interface [polypeptide binding]; other site
1429244011332	active site 2 [active]
1429244011333	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244011334	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244011335	dimerization interface [polypeptide binding]; other site
1429244011336	putative DNA binding site [nucleotide binding]; other site
1429244011337	putative Zn2+ binding site [ion binding]; other site
1429244011338	glutamate dehydrogenase; Provisional; Region: PRK09414
1429244011339	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1429244011340	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1429244011341	NAD(P) binding site [chemical binding]; other site
1429244011342	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1429244011343	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1429244011344	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244011345	catalytic residue [active]
1429244011346	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1429244011347	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1429244011348	AAA domain; Region: AAA_23; pfam13476
1429244011349	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244011350	Walker A/P-loop; other site
1429244011351	ATP binding site [chemical binding]; other site
1429244011352	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
1429244011353	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244011354	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
1429244011355	DGC domain; Region: DGC; pfam08859
1429244011356	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244011357	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244011358	catalytic residue [active]
1429244011359	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244011360	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1429244011361	Horizontally Transferred TransMembrane Domain; Region: HTTM; smart00752
1429244011362	Protein of unknown function, DUF393; Region: DUF393; pfam04134
1429244011363	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246
1429244011364	putative dimer interface [polypeptide binding]; other site
1429244011365	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244011366	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_3; cd03140
1429244011367	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1429244011368	conserved cys residue [active]
1429244011369	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244011370	HTH domain; Region: HTH_11; pfam08279
1429244011371	WYL domain; Region: WYL; pfam13280
1429244011372	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244011373	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1429244011374	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244011375	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244011376	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
1429244011377	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244011378	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244011379	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244011380	dimer interface [polypeptide binding]; other site
1429244011381	conserved gate region; other site
1429244011382	putative PBP binding loops; other site
1429244011383	ABC-ATPase subunit interface; other site
1429244011384	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244011385	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244011386	dimer interface [polypeptide binding]; other site
1429244011387	conserved gate region; other site
1429244011388	putative PBP binding loops; other site
1429244011389	ABC-ATPase subunit interface; other site
1429244011390	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244011391	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244011392	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244011393	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244011394	active site
1429244011395	phosphorylation site [posttranslational modification]
1429244011396	intermolecular recognition site; other site
1429244011397	dimerization interface [polypeptide binding]; other site
1429244011398	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011399	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244011400	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011401	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1429244011402	dimerization interface [polypeptide binding]; other site
1429244011403	Histidine kinase; Region: His_kinase; pfam06580
1429244011404	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244011405	ATP binding site [chemical binding]; other site
1429244011406	Mg2+ binding site [ion binding]; other site
1429244011407	G-X-G motif; other site
1429244011408	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244011409	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244011410	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1429244011411	HEAT repeats; Region: HEAT_2; pfam13646
1429244011412	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cl00425
1429244011413	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1429244011414	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1429244011415	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244011416	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244011417	DNA binding site [nucleotide binding]
1429244011418	domain linker motif; other site
1429244011419	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
1429244011420	putative dimerization interface [polypeptide binding]; other site
1429244011421	putative ligand binding site [chemical binding]; other site
1429244011422	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1429244011423	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
1429244011424	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1429244011425	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244011426	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244011427	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244011428	Domain of unknown function (DUF4183); Region: DUF4183; pfam13799
1429244011429	Domain of unknown function (DUF4183); Region: DUF4183; pfam13799
1429244011430	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1429244011431	Spore germination protein; Region: Spore_permease; cl17796
1429244011432	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244011433	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244011434	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244011435	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1429244011436	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1429244011437	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
1429244011438	Pectate lyase [Carbohydrate transport and metabolism]; Region: PelB; COG3866
1429244011439	Amb_all domain; Region: Amb_all; smart00656
1429244011440	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244011441	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244011442	Walker A/P-loop; other site
1429244011443	ATP binding site [chemical binding]; other site
1429244011444	Q-loop/lid; other site
1429244011445	ABC transporter signature motif; other site
1429244011446	Walker B; other site
1429244011447	D-loop; other site
1429244011448	H-loop/switch region; other site
1429244011449	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1429244011450	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244011451	HAMP domain; Region: HAMP; pfam00672
1429244011452	dimerization interface [polypeptide binding]; other site
1429244011453	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244011454	dimer interface [polypeptide binding]; other site
1429244011455	phosphorylation site [posttranslational modification]
1429244011456	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244011457	ATP binding site [chemical binding]; other site
1429244011458	Mg2+ binding site [ion binding]; other site
1429244011459	G-X-G motif; other site
1429244011460	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244011461	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244011462	active site
1429244011463	phosphorylation site [posttranslational modification]
1429244011464	intermolecular recognition site; other site
1429244011465	dimerization interface [polypeptide binding]; other site
1429244011466	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244011467	DNA binding site [nucleotide binding]
1429244011468	H-type lectin domain; Region: H_lectin; pfam09458
1429244011469	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
1429244011470	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
1429244011471	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
1429244011472	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
1429244011473	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
1429244011474	Domain of unknown function (DUF4190); Region: DUF4190; pfam13828
1429244011475	Optic atrophy 3 protein (OPA3); Region: OPA3; pfam07047
1429244011476	type VII secretion-associated serine protease mycosin; Region: T7SS_mycosin; TIGR03921
1429244011477	Peptidase S8 family domain in BacillopeptidaseF-like proteins; Region: Peptidases_S8_BacillopeptidaseF-like; cd07481
1429244011478	active site
1429244011479	catalytic triad [active]
1429244011480	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
1429244011481	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4412
1429244011482	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
1429244011483	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1429244011484	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1429244011485	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1429244011486	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
1429244011487	Peptidase S8 family domain in BacillopeptidaseF-like proteins; Region: Peptidases_S8_BacillopeptidaseF-like; cd07481
1429244011488	active site
1429244011489	catalytic triad [active]
1429244011490	putative transporter; Provisional; Region: PRK11660
1429244011491	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1429244011492	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1429244011493	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1429244011494	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244011495	dimerization interface [polypeptide binding]; other site
1429244011496	putative DNA binding site [nucleotide binding]; other site
1429244011497	putative Zn2+ binding site [ion binding]; other site
1429244011498	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1429244011499	Uncharacterized protein family (UPF0262); Region: UPF0262; cl11489
1429244011500	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244011501	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1429244011502	Walker A motif; other site
1429244011503	ATP binding site [chemical binding]; other site
1429244011504	Walker B motif; other site
1429244011505	arginine finger; other site
1429244011506	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244011507	putative substrate translocation pore; other site
1429244011508	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244011509	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244011510	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244011511	Walker A/P-loop; other site
1429244011512	ATP binding site [chemical binding]; other site
1429244011513	Q-loop/lid; other site
1429244011514	ABC transporter signature motif; other site
1429244011515	Walker B; other site
1429244011516	D-loop; other site
1429244011517	H-loop/switch region; other site
1429244011518	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1429244011519	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244011520	dimer interface [polypeptide binding]; other site
1429244011521	conserved gate region; other site
1429244011522	putative PBP binding loops; other site
1429244011523	ABC-ATPase subunit interface; other site
1429244011524	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244011525	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244011526	substrate binding pocket [chemical binding]; other site
1429244011527	membrane-bound complex binding site; other site
1429244011528	hinge residues; other site
1429244011529	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244011530	H+ Antiporter protein; Region: 2A0121; TIGR00900
1429244011531	putative substrate translocation pore; other site
1429244011532	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
1429244011533	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244011534	Domain of unknown function (DUF3817); Region: DUF3817; pfam12823
1429244011535	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1429244011536	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1429244011537	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1429244011538	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
1429244011539	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1429244011540	Cellulose binding domain; Region: CBM_3; pfam00942
1429244011541	dihydroxyacetone kinase; Provisional; Region: PRK14479
1429244011542	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
1429244011543	DAK2 domain; Region: Dak2; pfam02734
1429244011544	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1429244011545	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1429244011546	dimer interface [polypeptide binding]; other site
1429244011547	active site
1429244011548	metal binding site [ion binding]; metal-binding site
1429244011549	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
1429244011550	Sensory domain found in PocR; Region: PocR; pfam10114
1429244011551	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244011552	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011553	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011554	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
1429244011555	SUKH-3 immunity protein; Region: SUKH-3; pfam14433
1429244011556	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
1429244011557	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244011558	RDD family; Region: RDD; pfam06271
1429244011559	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1429244011560	nucleotide binding site [chemical binding]; other site
1429244011561	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
1429244011562	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
1429244011563	active site
1429244011564	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1429244011565	phosphopeptide binding site; other site
1429244011566	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
1429244011567	phosphopeptide binding site; other site
1429244011568	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
1429244011569	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1429244011570	HSP70 interaction site [polypeptide binding]; other site
1429244011571	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1429244011572	metal ion-dependent adhesion site (MIDAS); other site
1429244011573	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
1429244011574	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1429244011575	active site
1429244011576	ATP binding site [chemical binding]; other site
1429244011577	substrate binding site [chemical binding]; other site
1429244011578	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1429244011579	activation loop (A-loop); other site
1429244011580	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1429244011581	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244011582	putative substrate translocation pore; other site
1429244011583	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1429244011584	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244011585	active site
1429244011586	phosphorylation site [posttranslational modification]
1429244011587	intermolecular recognition site; other site
1429244011588	dimerization interface [polypeptide binding]; other site
1429244011589	LytTr DNA-binding domain; Region: LytTR; smart00850
1429244011590	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1429244011591	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1429244011592	GAF domain; Region: GAF; cl17456
1429244011593	Histidine kinase; Region: His_kinase; pfam06580
1429244011594	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244011595	ATP binding site [chemical binding]; other site
1429244011596	Mg2+ binding site [ion binding]; other site
1429244011597	G-X-G motif; other site
1429244011598	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1429244011599	putative dimer interface [polypeptide binding]; other site
1429244011600	catalytic triad [active]
1429244011601	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
1429244011602	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244011603	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244011604	dimer interface [polypeptide binding]; other site
1429244011605	putative CheW interface [polypeptide binding]; other site
1429244011606	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1429244011607	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1429244011608	5S rRNA interface [nucleotide binding]; other site
1429244011609	CTC domain interface [polypeptide binding]; other site
1429244011610	L16 interface [polypeptide binding]; other site
1429244011611	pullulanase, type I; Region: pulA_typeI; TIGR02104
1429244011612	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
1429244011613	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
1429244011614	Ca binding site [ion binding]; other site
1429244011615	active site
1429244011616	catalytic site [active]
1429244011617	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
1429244011618	carbohydrate binding site [chemical binding]; other site
1429244011619	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
1429244011620	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244011621	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244011622	Walker A/P-loop; other site
1429244011623	ATP binding site [chemical binding]; other site
1429244011624	Q-loop/lid; other site
1429244011625	ABC transporter signature motif; other site
1429244011626	Walker B; other site
1429244011627	D-loop; other site
1429244011628	H-loop/switch region; other site
1429244011629	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2832
1429244011630	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244011631	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1429244011632	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244011633	Walker A/P-loop; other site
1429244011634	ATP binding site [chemical binding]; other site
1429244011635	Q-loop/lid; other site
1429244011636	ABC transporter signature motif; other site
1429244011637	Walker B; other site
1429244011638	D-loop; other site
1429244011639	H-loop/switch region; other site
1429244011640	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1429244011641	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1429244011642	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1429244011643	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244011644	active site
1429244011645	phosphorylation site [posttranslational modification]
1429244011646	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1429244011647	HTH domain; Region: HTH_11; pfam08279
1429244011648	PRD domain; Region: PRD; pfam00874
1429244011649	PRD domain; Region: PRD; pfam00874
1429244011650	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1429244011651	active site
1429244011652	P-loop; other site
1429244011653	phosphorylation site [posttranslational modification]
1429244011654	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
1429244011655	active site
1429244011656	phosphorylation site [posttranslational modification]
1429244011657	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1429244011658	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1429244011659	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1429244011660	active site
1429244011661	P-loop; other site
1429244011662	phosphorylation site [posttranslational modification]
1429244011663	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1429244011664	lipoyl attachment site [posttranslational modification]; other site
1429244011665	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1429244011666	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1429244011667	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
1429244011668	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1429244011669	tetramer interface [polypeptide binding]; other site
1429244011670	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244011671	catalytic residue [active]
1429244011672	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1429244011673	tetramer interface [polypeptide binding]; other site
1429244011674	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244011675	catalytic residue [active]
1429244011676	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1429244011677	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1429244011678	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1429244011679	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1429244011680	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1429244011681	dimerization domain swap beta strand [polypeptide binding]; other site
1429244011682	regulatory protein interface [polypeptide binding]; other site
1429244011683	active site
1429244011684	regulatory phosphorylation site [posttranslational modification]; other site
1429244011685	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244011686	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1429244011687	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244011688	active site turn [active]
1429244011689	phosphorylation site [posttranslational modification]
1429244011690	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244011691	HPr interaction site; other site
1429244011692	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244011693	active site
1429244011694	phosphorylation site [posttranslational modification]
1429244011695	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244011696	CAT RNA binding domain; Region: CAT_RBD; pfam03123
1429244011697	PRD domain; Region: PRD; pfam00874
1429244011698	PRD domain; Region: PRD; pfam00874
1429244011699	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1429244011700	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1429244011701	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1429244011702	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1429244011703	dimer interface [polypeptide binding]; other site
1429244011704	active site
1429244011705	metal binding site [ion binding]; metal-binding site
1429244011706	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
1429244011707	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
1429244011708	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
1429244011709	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1429244011710	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1429244011711	NAD binding site [chemical binding]; other site
1429244011712	homodimer interface [polypeptide binding]; other site
1429244011713	active site
1429244011714	substrate binding site [chemical binding]; other site
1429244011715	galactokinase; Provisional; Region: PRK05322
1429244011716	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1429244011717	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1429244011718	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1429244011719	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244011720	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011721	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244011722	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244011723	NAD-dependent deacetylase; Provisional; Region: PRK00481
1429244011724	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1429244011725	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1429244011726	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244011727	motif II; other site
1429244011728	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1429244011729	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1429244011730	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1429244011731	General stress protein [General function prediction only]; Region: GsiB; COG3729
1429244011732	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1429244011733	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1429244011734	Catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases; Region: CE4_NodB_like_3; cd10959
1429244011735	NodB motif; other site
1429244011736	putative active site [active]
1429244011737	putative catalytic site [active]
1429244011738	putative Zn binding site [ion binding]; other site
1429244011739	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1429244011740	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1429244011741	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1429244011742	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1429244011743	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1429244011744	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244011745	dimerization interface [polypeptide binding]; other site
1429244011746	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244011747	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244011748	dimer interface [polypeptide binding]; other site
1429244011749	putative CheW interface [polypeptide binding]; other site
1429244011750	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1429244011751	Peptidase family U32; Region: Peptidase_U32; pfam01136
1429244011752	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1429244011753	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1429244011754	Peptidase family U32; Region: Peptidase_U32; pfam01136
1429244011755	YceG-like family; Region: YceG; pfam02618
1429244011756	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1429244011757	dimerization interface [polypeptide binding]; other site
1429244011758	hypothetical protein; Provisional; Region: PRK13678
1429244011759	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
1429244011760	hypothetical protein; Provisional; Region: PRK05473
1429244011761	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1429244011762	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1429244011763	motif 1; other site
1429244011764	active site
1429244011765	motif 2; other site
1429244011766	motif 3; other site
1429244011767	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1429244011768	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1429244011769	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1429244011770	Cache domain; Region: Cache_1; pfam02743
1429244011771	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1429244011772	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244011773	dimerization interface [polypeptide binding]; other site
1429244011774	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244011775	dimer interface [polypeptide binding]; other site
1429244011776	putative CheW interface [polypeptide binding]; other site
1429244011777	PRC-barrel domain; Region: PRC; pfam05239
1429244011778	PRC-barrel domain; Region: PRC; pfam05239
1429244011779	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1429244011780	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1429244011781	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244011782	catalytic residue [active]
1429244011783	Predicted transcriptional regulator [Transcription]; Region: COG1959
1429244011784	Transcriptional regulator; Region: Rrf2; pfam02082
1429244011785	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1429244011786	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1429244011787	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
1429244011788	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
1429244011789	CrcB-like protein; Region: CRCB; pfam02537
1429244011790	recombination factor protein RarA; Reviewed; Region: PRK13342
1429244011791	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244011792	Walker A motif; other site
1429244011793	ATP binding site [chemical binding]; other site
1429244011794	Walker B motif; other site
1429244011795	arginine finger; other site
1429244011796	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1429244011797	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
1429244011798	Part of AAA domain; Region: AAA_19; pfam13245
1429244011799	Family description; Region: UvrD_C_2; pfam13538
1429244011800	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244011801	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244011802	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244011803	Walker A/P-loop; other site
1429244011804	ATP binding site [chemical binding]; other site
1429244011805	Q-loop/lid; other site
1429244011806	ABC transporter signature motif; other site
1429244011807	Walker B; other site
1429244011808	D-loop; other site
1429244011809	H-loop/switch region; other site
1429244011810	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1429244011811	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1429244011812	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1429244011813	putative ATP binding site [chemical binding]; other site
1429244011814	putative substrate interface [chemical binding]; other site
1429244011815	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1429244011816	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1429244011817	dimer interface [polypeptide binding]; other site
1429244011818	anticodon binding site; other site
1429244011819	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1429244011820	homodimer interface [polypeptide binding]; other site
1429244011821	motif 1; other site
1429244011822	active site
1429244011823	motif 2; other site
1429244011824	GAD domain; Region: GAD; pfam02938
1429244011825	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1429244011826	active site
1429244011827	motif 3; other site
1429244011828	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1429244011829	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1429244011830	dimer interface [polypeptide binding]; other site
1429244011831	motif 1; other site
1429244011832	active site
1429244011833	motif 2; other site
1429244011834	motif 3; other site
1429244011835	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1429244011836	anticodon binding site; other site
1429244011837	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1429244011838	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1429244011839	proposed catalytic triad [active]
1429244011840	conserved cys residue [active]
1429244011841	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1429244011842	putative active site [active]
1429244011843	dimerization interface [polypeptide binding]; other site
1429244011844	putative tRNAtyr binding site [nucleotide binding]; other site
1429244011845	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1429244011846	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244011847	Zn2+ binding site [ion binding]; other site
1429244011848	Mg2+ binding site [ion binding]; other site
1429244011849	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1429244011850	synthetase active site [active]
1429244011851	NTP binding site [chemical binding]; other site
1429244011852	metal binding site [ion binding]; metal-binding site
1429244011853	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1429244011854	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1429244011855	uracil transporter; Provisional; Region: PRK10720
1429244011856	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244011857	active site
1429244011858	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1429244011859	DHH family; Region: DHH; pfam01368
1429244011860	DHHA1 domain; Region: DHHA1; pfam02272
1429244011861	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
1429244011862	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1429244011863	Cation efflux family; Region: Cation_efflux; pfam01545
1429244011864	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1429244011865	Protein export membrane protein; Region: SecD_SecF; pfam02355
1429244011866	protein-export membrane protein SecD; Region: secD; TIGR01129
1429244011867	Class I aldolases; Region: Aldolase_Class_I; cl17187
1429244011868	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1429244011869	Post-transcriptional regulator; Region: Post_transc_reg; pfam13797
1429244011870	stage V sporulation protein B; Region: spore_V_B; TIGR02900
1429244011871	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1429244011872	Predicted membrane protein [Function unknown]; Region: COG2323
1429244011873	putative membrane protein, TIGR04086 family; Region: TIGR04086_membr
1429244011874	Preprotein translocase subunit; Region: YajC; pfam02699
1429244011875	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1429244011876	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1429244011877	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1429244011878	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1429244011879	Sporulation related domain; Region: SPOR; cl10051
1429244011880	Stage II sporulation protein; Region: SpoIID; pfam08486
1429244011881	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1429244011882	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1429244011883	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244011884	Walker A motif; other site
1429244011885	ATP binding site [chemical binding]; other site
1429244011886	Walker B motif; other site
1429244011887	arginine finger; other site
1429244011888	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1429244011889	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1429244011890	RuvA N terminal domain; Region: RuvA_N; pfam01330
1429244011891	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1429244011892	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1429244011893	active site
1429244011894	putative DNA-binding cleft [nucleotide binding]; other site
1429244011895	dimer interface [polypeptide binding]; other site
1429244011896	BofC C-terminal domain; Region: BofC_C; pfam08955
1429244011897	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244011898	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1429244011899	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244011900	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1429244011901	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
1429244011902	homodimer interface [polypeptide binding]; other site
1429244011903	substrate-cofactor binding pocket; other site
1429244011904	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244011905	catalytic residue [active]
1429244011906	prephenate dehydratase; Provisional; Region: PRK11898
1429244011907	Prephenate dehydratase; Region: PDT; pfam00800
1429244011908	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1429244011909	putative L-Phe binding site [chemical binding]; other site
1429244011910	homoserine kinase; Provisional; Region: PRK01212
1429244011911	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1429244011912	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1429244011913	homoserine dehydrogenase; Provisional; Region: PRK06349
1429244011914	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1429244011915	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1429244011916	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1429244011917	hypothetical protein; Provisional; Region: PRK04435
1429244011918	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1429244011919	GTPase CgtA; Reviewed; Region: obgE; PRK12297
1429244011920	GTP1/OBG; Region: GTP1_OBG; pfam01018
1429244011921	Obg GTPase; Region: Obg; cd01898
1429244011922	G1 box; other site
1429244011923	GTP/Mg2+ binding site [chemical binding]; other site
1429244011924	Switch I region; other site
1429244011925	G2 box; other site
1429244011926	G3 box; other site
1429244011927	Switch II region; other site
1429244011928	G4 box; other site
1429244011929	G5 box; other site
1429244011930	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1429244011931	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1429244011932	Protein of unknown function (DUF464); Region: DUF464; pfam04327
1429244011933	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1429244011934	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1429244011935	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1429244011936	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1429244011937	homodimer interface [polypeptide binding]; other site
1429244011938	oligonucleotide binding site [chemical binding]; other site
1429244011939	SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F...; Region: S2P-M50_SpoIVFB; cd06161
1429244011940	Peptidase family M50; Region: Peptidase_M50; pfam02163
1429244011941	active site
1429244011942	putative substrate binding region [chemical binding]; other site
1429244011943	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244011944	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1429244011945	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1429244011946	Switch I; other site
1429244011947	Switch II; other site
1429244011948	septum formation inhibitor; Reviewed; Region: minC; PRK00513
1429244011949	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1429244011950	rod shape-determining protein MreD; Region: MreD; cl01087
1429244011951	rod shape-determining protein MreC; Provisional; Region: PRK13922
1429244011952	rod shape-determining protein MreC; Region: MreC; pfam04085
1429244011953	rod shape-determining protein MreB; Provisional; Region: PRK13927
1429244011954	MreB and similar proteins; Region: MreB_like; cd10225
1429244011955	nucleotide binding site [chemical binding]; other site
1429244011956	Mg binding site [ion binding]; other site
1429244011957	putative protofilament interaction site [polypeptide binding]; other site
1429244011958	RodZ interaction site [polypeptide binding]; other site
1429244011959	hypothetical protein; Reviewed; Region: PRK00024
1429244011960	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1429244011961	MPN+ (JAMM) motif; other site
1429244011962	Zinc-binding site [ion binding]; other site
1429244011963	Maf-like protein; Reviewed; Region: PRK00078
1429244011964	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1429244011965	active site
1429244011966	dimer interface [polypeptide binding]; other site
1429244011967	Sporulation related domain; Region: SPOR; pfam05036
1429244011968	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1429244011969	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1429244011970	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1429244011971	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1429244011972	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1429244011973	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1429244011974	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1429244011975	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1429244011976	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1429244011977	active site
1429244011978	HIGH motif; other site
1429244011979	nucleotide binding site [chemical binding]; other site
1429244011980	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1429244011981	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1429244011982	active site
1429244011983	KMSKS motif; other site
1429244011984	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1429244011985	tRNA binding surface [nucleotide binding]; other site
1429244011986	anticodon binding site; other site
1429244011987	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1429244011988	stage VI sporulation protein D; Region: spore_VI_D; TIGR02907
1429244011989	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244011990	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1429244011991	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1429244011992	active site
1429244011993	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1429244011994	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1429244011995	inhibitor-cofactor binding pocket; inhibition site
1429244011996	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244011997	catalytic residue [active]
1429244011998	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1429244011999	dimer interface [polypeptide binding]; other site
1429244012000	active site
1429244012001	Schiff base residues; other site
1429244012002	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1429244012003	active site
1429244012004	SAM binding site [chemical binding]; other site
1429244012005	homodimer interface [polypeptide binding]; other site
1429244012006	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1429244012007	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1429244012008	active site
1429244012009	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1429244012010	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1429244012011	domain interfaces; other site
1429244012012	active site
1429244012013	precorrin-2 dehydrogenase; Reviewed; Region: PRK06718
1429244012014	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1429244012015	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1429244012016	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1429244012017	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1429244012018	tRNA; other site
1429244012019	putative tRNA binding site [nucleotide binding]; other site
1429244012020	putative NADP binding site [chemical binding]; other site
1429244012021	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1429244012022	S-adenosylmethionine decarboxylase proenzyme; Validated; Region: PRK01706
1429244012023	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1429244012024	G1 box; other site
1429244012025	GTP/Mg2+ binding site [chemical binding]; other site
1429244012026	Switch I region; other site
1429244012027	G2 box; other site
1429244012028	G3 box; other site
1429244012029	Switch II region; other site
1429244012030	G4 box; other site
1429244012031	G5 box; other site
1429244012032	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1429244012033	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244012034	Walker A motif; other site
1429244012035	ATP binding site [chemical binding]; other site
1429244012036	Walker B motif; other site
1429244012037	arginine finger; other site
1429244012038	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1429244012039	ATP-dependent protease LonB; Region: spore_lonB; TIGR02902
1429244012040	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244012041	Walker A motif; other site
1429244012042	ATP binding site [chemical binding]; other site
1429244012043	Walker B motif; other site
1429244012044	arginine finger; other site
1429244012045	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1429244012046	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1429244012047	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1429244012048	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1429244012049	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1429244012050	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1429244012051	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244012052	Walker A motif; other site
1429244012053	ATP binding site [chemical binding]; other site
1429244012054	Walker B motif; other site
1429244012055	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1429244012056	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1429244012057	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1429244012058	oligomer interface [polypeptide binding]; other site
1429244012059	active site residues [active]
1429244012060	trigger factor; Provisional; Region: tig; PRK01490
1429244012061	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1429244012062	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1429244012063	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1429244012064	active site
1429244012065	putative catalytic site [active]
1429244012066	DNA binding site [nucleotide binding]
1429244012067	putative phosphate binding site [ion binding]; other site
1429244012068	metal binding site A [ion binding]; metal-binding site
1429244012069	AP binding site [nucleotide binding]; other site
1429244012070	metal binding site B [ion binding]; metal-binding site
1429244012071	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
1429244012072	beta-galactosidase; Region: BGL; TIGR03356
1429244012073	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244012074	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244012075	dimer interface [polypeptide binding]; other site
1429244012076	conserved gate region; other site
1429244012077	putative PBP binding loops; other site
1429244012078	ABC-ATPase subunit interface; other site
1429244012079	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244012080	dimer interface [polypeptide binding]; other site
1429244012081	conserved gate region; other site
1429244012082	putative PBP binding loops; other site
1429244012083	ABC-ATPase subunit interface; other site
1429244012084	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1429244012085	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244012086	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244012087	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244012088	DNA binding site [nucleotide binding]
1429244012089	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244012090	dimerization interface [polypeptide binding]; other site
1429244012091	ligand binding site [chemical binding]; other site
1429244012092	glycerol kinase; Provisional; Region: glpK; PRK00047
1429244012093	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1429244012094	N- and C-terminal domain interface [polypeptide binding]; other site
1429244012095	active site
1429244012096	MgATP binding site [chemical binding]; other site
1429244012097	catalytic site [active]
1429244012098	metal binding site [ion binding]; metal-binding site
1429244012099	glycerol binding site [chemical binding]; other site
1429244012100	homotetramer interface [polypeptide binding]; other site
1429244012101	homodimer interface [polypeptide binding]; other site
1429244012102	FBP binding site [chemical binding]; other site
1429244012103	protein IIAGlc interface [polypeptide binding]; other site
1429244012104	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1429244012105	amphipathic channel; other site
1429244012106	Asn-Pro-Ala signature motifs; other site
1429244012107	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
1429244012108	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244012109	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244012110	active site turn [active]
1429244012111	phosphorylation site [posttranslational modification]
1429244012112	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1429244012113	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
1429244012114	phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK01293
1429244012115	malonate decarboxylase, beta subunit; Region: malonate_beta; TIGR03133
1429244012116	malonate decarboxylase, gamma subunit; Region: malonate_gamma; TIGR03134
1429244012117	Malonate decarboxylase delta subunit (MdcD); Region: ACP; cl06082
1429244012118	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
1429244012119	malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110
1429244012120	Coenzyme A transferase; Region: CoA_trans; cl17247
1429244012121	malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131
1429244012122	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244012123	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244012124	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1429244012125	dimerization interface [polypeptide binding]; other site
1429244012126	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244012127	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244012128	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244012129	dimer interface [polypeptide binding]; other site
1429244012130	conserved gate region; other site
1429244012131	putative PBP binding loops; other site
1429244012132	ABC-ATPase subunit interface; other site
1429244012133	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244012134	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244012135	dimer interface [polypeptide binding]; other site
1429244012136	conserved gate region; other site
1429244012137	putative PBP binding loops; other site
1429244012138	ABC-ATPase subunit interface; other site
1429244012139	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1429244012140	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1429244012141	dimer interface [polypeptide binding]; other site
1429244012142	active site
1429244012143	metal binding site [ion binding]; metal-binding site
1429244012144	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1429244012145	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1429244012146	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244012147	beta-galactosidase; Region: BGL; TIGR03356
1429244012148	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244012149	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244012150	DNA binding site [nucleotide binding]
1429244012151	domain linker motif; other site
1429244012152	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1429244012153	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244012154	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244012155	PRD domain; Region: PRD; pfam00874
1429244012156	PRD domain; Region: PRD; pfam00874
1429244012157	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1429244012158	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244012159	active site turn [active]
1429244012160	phosphorylation site [posttranslational modification]
1429244012161	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244012162	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244012163	HPr interaction site; other site
1429244012164	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244012165	active site
1429244012166	phosphorylation site [posttranslational modification]
1429244012167	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244012168	catalytic residues [active]
1429244012169	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244012170	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1429244012171	active site
1429244012172	Cupin domain; Region: Cupin_2; cl17218
1429244012173	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244012174	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244012175	active site
1429244012176	phosphorylation site [posttranslational modification]
1429244012177	intermolecular recognition site; other site
1429244012178	dimerization interface [polypeptide binding]; other site
1429244012179	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244012180	DNA binding site [nucleotide binding]
1429244012181	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1429244012182	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244012183	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
1429244012184	ATP binding site [chemical binding]; other site
1429244012185	Mg2+ binding site [ion binding]; other site
1429244012186	G-X-G motif; other site
1429244012187	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244012188	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244012189	active site
1429244012190	phosphorylation site [posttranslational modification]
1429244012191	intermolecular recognition site; other site
1429244012192	dimerization interface [polypeptide binding]; other site
1429244012193	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244012194	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244012195	active site
1429244012196	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244012197	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244012198	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244012199	active site
1429244012200	malate dehydrogenase; Provisional; Region: PRK13529
1429244012201	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1429244012202	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1429244012203	NAD(P) binding site [chemical binding]; other site
1429244012204	Putative transcription activator [Transcription]; Region: TenA; COG0819
1429244012205	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1429244012206	substrate binding site [chemical binding]; other site
1429244012207	multimerization interface [polypeptide binding]; other site
1429244012208	ATP binding site [chemical binding]; other site
1429244012209	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1429244012210	dimer interface [polypeptide binding]; other site
1429244012211	substrate binding site [chemical binding]; other site
1429244012212	ATP binding site [chemical binding]; other site
1429244012213	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1429244012214	thiamine phosphate binding site [chemical binding]; other site
1429244012215	active site
1429244012216	pyrophosphate binding site [ion binding]; other site
1429244012217	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1429244012218	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244012219	non-specific DNA binding site [nucleotide binding]; other site
1429244012220	salt bridge; other site
1429244012221	sequence-specific DNA binding site [nucleotide binding]; other site
1429244012222	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244012223	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244012224	DNA binding site [nucleotide binding]
1429244012225	domain linker motif; other site
1429244012226	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1429244012227	putative dimerization interface [polypeptide binding]; other site
1429244012228	putative ligand binding site [chemical binding]; other site
1429244012229	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1429244012230	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1429244012231	NAD binding site [chemical binding]; other site
1429244012232	sugar binding site [chemical binding]; other site
1429244012233	divalent metal binding site [ion binding]; other site
1429244012234	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244012235	dimer interface [polypeptide binding]; other site
1429244012236	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1429244012237	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1429244012238	FMN binding site [chemical binding]; other site
1429244012239	substrate binding site [chemical binding]; other site
1429244012240	putative catalytic residue [active]
1429244012241	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244012242	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244012243	Tic20-like protein; Region: Tic20; pfam09685
1429244012244	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1429244012245	active site
1429244012246	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
1429244012247	dimer interface [polypeptide binding]; other site
1429244012248	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1429244012249	Ligand Binding Site [chemical binding]; other site
1429244012250	Molecular Tunnel; other site
1429244012251	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1429244012252	active site
1429244012253	dimerization interface [polypeptide binding]; other site
1429244012254	ribonuclease PH; Reviewed; Region: rph; PRK00173
1429244012255	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1429244012256	hexamer interface [polypeptide binding]; other site
1429244012257	active site
1429244012258	Spore germination protein [General function prediction only]; Region: COG5401
1429244012259	Sporulation and spore germination; Region: Germane; pfam10646
1429244012260	Sporulation and spore germination; Region: Germane; pfam10646
1429244012261	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1429244012262	tetramer interfaces [polypeptide binding]; other site
1429244012263	binuclear metal-binding site [ion binding]; other site
1429244012264	putative acetyltransferase; Provisional; Region: PRK03624
1429244012265	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244012266	Coenzyme A binding pocket [chemical binding]; other site
1429244012267	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1429244012268	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244012269	NAD(P) binding site [chemical binding]; other site
1429244012270	active site
1429244012271	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244012272	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244012273	WHG domain; Region: WHG; pfam13305
1429244012274	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1429244012275	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1429244012276	NAD binding site [chemical binding]; other site
1429244012277	putative active site [active]
1429244012278	substrate binding site [chemical binding]; other site
1429244012279	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244012280	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244012281	S-adenosylmethionine binding site [chemical binding]; other site
1429244012282	Protein of unknown function DUF72; Region: DUF72; pfam01904
1429244012283	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1429244012284	putative metal binding site; other site
1429244012285	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244012286	binding surface
1429244012287	TPR motif; other site
1429244012288	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1429244012289	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244012290	S-adenosylmethionine binding site [chemical binding]; other site
1429244012291	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
1429244012292	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244012293	NAD(P) binding site [chemical binding]; other site
1429244012294	active site
1429244012295	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1429244012296	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1429244012297	Putative rhamnosyl transferase; Region: Rhamno_transf; pfam11316
1429244012298	Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Region: Endoglucanase_E_like; cd01831
1429244012299	active site
1429244012300	catalytic triad [active]
1429244012301	oxyanion hole [active]
1429244012302	Cache domain; Region: Cache_1; pfam02743
1429244012303	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244012304	dimerization interface [polypeptide binding]; other site
1429244012305	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244012306	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244012307	dimer interface [polypeptide binding]; other site
1429244012308	putative CheW interface [polypeptide binding]; other site
1429244012309	Putative motility protein; Region: YjfB_motility; pfam14070
1429244012310	hypothetical protein; Provisional; Region: PRK08201
1429244012311	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
1429244012312	metal binding site [ion binding]; metal-binding site
1429244012313	putative dimer interface [polypeptide binding]; other site
1429244012314	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1429244012315	Methyltransferase domain; Region: Methyltransf_25; pfam13649
1429244012316	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244012317	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244012318	DNA binding residues [nucleotide binding]
1429244012319	dimerization interface [polypeptide binding]; other site
1429244012320	Imelysin; Region: Peptidase_M75; pfam09375
1429244012321	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1429244012322	High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672
1429244012323	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Btrk Decarboxylase; Region: PLPDE_III_Btrk_like; cd06839
1429244012324	pyridoxal-dependent decarboxylase, exosortase A system-associated; Region: dCO2ase_PEP1; TIGR03099
1429244012325	dimer interface [polypeptide binding]; other site
1429244012326	active site
1429244012327	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1429244012328	catalytic residues [active]
1429244012329	substrate binding site [chemical binding]; other site
1429244012330	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244012331	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244012332	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane]; Region: MurG; COG0707
1429244012333	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
1429244012334	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587
1429244012335	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586
1429244012336	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244012337	Walker A/P-loop; other site
1429244012338	ATP binding site [chemical binding]; other site
1429244012339	Q-loop/lid; other site
1429244012340	ABC transporter signature motif; other site
1429244012341	Walker B; other site
1429244012342	D-loop; other site
1429244012343	H-loop/switch region; other site
1429244012344	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244012345	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1429244012346	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244012347	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1429244012348	FeS/SAM binding site; other site
1429244012349	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1429244012350	acyl carrier protein; Provisional; Region: PRK07081
1429244012351	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1429244012352	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1429244012353	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1429244012354	putative active site [active]
1429244012355	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1429244012356	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1429244012357	active site
1429244012358	trimer interface [polypeptide binding]; other site
1429244012359	allosteric site; other site
1429244012360	active site lid [active]
1429244012361	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1429244012362	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1429244012363	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1429244012364	active site
1429244012365	dimer interface [polypeptide binding]; other site
1429244012366	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
1429244012367	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
1429244012368	PGAP1-like protein; Region: PGAP1; pfam07819
1429244012369	YvrJ protein family; Region: YvrJ; pfam12841
1429244012370	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
1429244012371	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
1429244012372	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
1429244012373	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244012374	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
1429244012375	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1429244012376	Walker A/P-loop; other site
1429244012377	ATP binding site [chemical binding]; other site
1429244012378	Q-loop/lid; other site
1429244012379	ABC transporter signature motif; other site
1429244012380	Walker B; other site
1429244012381	D-loop; other site
1429244012382	H-loop/switch region; other site
1429244012383	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1429244012384	putative metal binding site; other site
1429244012385	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1429244012386	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244012387	binding surface
1429244012388	TPR motif; other site
1429244012389	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244012390	active site
1429244012391	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1429244012392	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244012393	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1429244012394	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244012395	active site turn [active]
1429244012396	phosphorylation site [posttranslational modification]
1429244012397	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244012398	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244012399	HPr interaction site; other site
1429244012400	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244012401	active site
1429244012402	phosphorylation site [posttranslational modification]
1429244012403	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244012404	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
1429244012405	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244012406	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244012407	DNA binding site [nucleotide binding]
1429244012408	domain linker motif; other site
1429244012409	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1429244012410	ligand binding site [chemical binding]; other site
1429244012411	dimerization interface [polypeptide binding]; other site
1429244012412	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1429244012413	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1429244012414	Rrf2 family protein; Region: rrf2_super; TIGR00738
1429244012415	Transcriptional regulator; Region: Rrf2; pfam02082
1429244012416	HTH domain; Region: HTH_11; pfam08279
1429244012417	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1429244012418	Mga helix-turn-helix domain; Region: Mga; pfam05043
1429244012419	PRD domain; Region: PRD; pfam00874
1429244012420	PRD domain; Region: PRD; pfam00874
1429244012421	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1429244012422	active site
1429244012423	P-loop; other site
1429244012424	phosphorylation site [posttranslational modification]
1429244012425	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244012426	active site
1429244012427	phosphorylation site [posttranslational modification]
1429244012428	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1429244012429	active site
1429244012430	methionine cluster; other site
1429244012431	phosphorylation site [posttranslational modification]
1429244012432	metal binding site [ion binding]; metal-binding site
1429244012433	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1429244012434	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1429244012435	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244012436	beta-galactosidase; Region: BGL; TIGR03356
1429244012437	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1429244012438	active site
1429244012439	P-loop; other site
1429244012440	phosphorylation site [posttranslational modification]
1429244012441	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1429244012442	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244012443	NAD(P) binding site [chemical binding]; other site
1429244012444	active site
1429244012445	Putative papain-like cysteine peptidase (DUF1796); Region: DUF1796; pfam08795
1429244012446	Putative papain-like cysteine peptidase (DUF1796); Region: DUF1796; pfam08795
1429244012447	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244012448	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244012449	BNR repeat-like domain; Region: BNR_2; pfam13088
1429244012450	BNR repeat-like domain; Region: BNR_2; pfam13088
1429244012451	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
1429244012452	Asp-box motif; other site
1429244012453	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1429244012454	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244012455	active site
1429244012456	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244012457	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244012458	active site
1429244012459	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244012460	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1429244012461	NAD(P) binding site [chemical binding]; other site
1429244012462	active site
1429244012463	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
1429244012464	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1429244012465	NADP binding site [chemical binding]; other site
1429244012466	active site
1429244012467	putative substrate binding site [chemical binding]; other site
1429244012468	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1429244012469	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1429244012470	active site
1429244012471	homodimer interface [polypeptide binding]; other site
1429244012472	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244012473	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244012474	DUF based on E. rectale Gene description (DUF3880); Region: DUF3880; pfam12996
1429244012475	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1429244012476	DUF based on E. rectale Gene description (DUF3880); Region: DUF3880; pfam12996
1429244012477	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1429244012478	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1429244012479	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1429244012480	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244012481	active site
1429244012482	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244012483	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1429244012484	active site
1429244012485	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1429244012486	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1429244012487	Probable Catalytic site; other site
1429244012488	metal-binding site
1429244012489	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244012490	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244012491	active site
1429244012492	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244012493	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1429244012494	active site
1429244012495	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
1429244012496	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1429244012497	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1429244012498	active site
1429244012499	Zn binding site [ion binding]; other site
1429244012500	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
1429244012501	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1429244012502	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1429244012503	active site
1429244012504	Zn binding site [ion binding]; other site
1429244012505	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1429244012506	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1429244012507	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244012508	Phosphatidylserine decarboxylase; Region: PS_Dcarbxylase; cl03656
1429244012509	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244012510	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244012511	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244012512	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1429244012513	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1429244012514	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244012515	homodimer interface [polypeptide binding]; other site
1429244012516	catalytic residue [active]
1429244012517	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1429244012518	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244012519	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244012520	dimer interface [polypeptide binding]; other site
1429244012521	phosphorylation site [posttranslational modification]
1429244012522	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244012523	ATP binding site [chemical binding]; other site
1429244012524	Mg2+ binding site [ion binding]; other site
1429244012525	G-X-G motif; other site
1429244012526	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
1429244012527	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1429244012528	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1429244012529	Walker A/P-loop; other site
1429244012530	ATP binding site [chemical binding]; other site
1429244012531	Q-loop/lid; other site
1429244012532	ABC transporter signature motif; other site
1429244012533	Walker B; other site
1429244012534	D-loop; other site
1429244012535	H-loop/switch region; other site
1429244012536	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1429244012537	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1429244012538	ATP binding site [chemical binding]; other site
1429244012539	Mg++ binding site [ion binding]; other site
1429244012540	motif III; other site
1429244012541	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244012542	nucleotide binding region [chemical binding]; other site
1429244012543	ATP-binding site [chemical binding]; other site
1429244012544	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1429244012545	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244012546	NAD(P) binding site [chemical binding]; other site
1429244012547	active site
1429244012548	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
1429244012549	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
1429244012550	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244012551	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244012552	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244012553	dimerization interface [polypeptide binding]; other site
1429244012554	histidinol-phosphatase; Provisional; Region: PRK07328
1429244012555	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
1429244012556	active site
1429244012557	dimer interface [polypeptide binding]; other site
1429244012558	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1429244012559	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1429244012560	synthetase active site [active]
1429244012561	NTP binding site [chemical binding]; other site
1429244012562	metal binding site [ion binding]; metal-binding site
1429244012563	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244012564	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244012565	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1429244012566	NAD(P) binding site [chemical binding]; other site
1429244012567	active site
1429244012568	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244012569	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244012570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244012571	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244012572	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244012573	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244012574	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244012575	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1429244012576	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1429244012577	active site
1429244012578	metal binding site [ion binding]; metal-binding site
1429244012579	phosphodiesterase YaeI; Provisional; Region: PRK11340
1429244012580	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1429244012581	putative active site [active]
1429244012582	putative metal binding site [ion binding]; other site
1429244012583	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; pfam02522
1429244012584	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK08640
1429244012585	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1429244012586	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08641
1429244012587	L-aspartate oxidase; Provisional; Region: PRK06175
1429244012588	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1429244012589	Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis...; Region: SQR_TypeB_1_TM; cd03497
1429244012590	putative Iron-sulfur protein interface [polypeptide binding]; other site
1429244012591	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
1429244012592	proximal heme binding site [chemical binding]; other site
1429244012593	distal heme binding site [chemical binding]; other site
1429244012594	putative dimer interface [polypeptide binding]; other site
1429244012595	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244012596	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244012597	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244012598	dimerization interface [polypeptide binding]; other site
1429244012599	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1429244012600	TrkA-N domain; Region: TrkA_N; pfam02254
1429244012601	TrkA-C domain; Region: TrkA_C; pfam02080
1429244012602	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1429244012603	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1429244012604	CAAX protease self-immunity; Region: Abi; pfam02517
1429244012605	excinuclease ABC subunit C; Provisional; Region: uvrC; PRK14666
1429244012606	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1429244012607	GIY-YIG motif/motif A; other site
1429244012608	active site
1429244012609	catalytic site [active]
1429244012610	putative DNA binding site [nucleotide binding]; other site
1429244012611	metal binding site [ion binding]; metal-binding site
1429244012612	UvrB/uvrC motif; Region: UVR; pfam02151
1429244012613	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1429244012614	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244012615	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1429244012616	catalytic residues [active]
1429244012617	primosomal protein DnaI; Reviewed; Region: PRK08939
1429244012618	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
1429244012619	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244012620	Walker A motif; other site
1429244012621	ATP binding site [chemical binding]; other site
1429244012622	Walker B motif; other site
1429244012623	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
1429244012624	putative heme peroxidase; Provisional; Region: PRK12276
1429244012625	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1429244012626	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1429244012627	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1429244012628	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1429244012629	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244012630	Outer membrane efflux protein; Region: OEP; pfam02321
1429244012631	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1429244012632	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244012633	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244012634	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244012635	putative DNA binding site [nucleotide binding]; other site
1429244012636	putative Zn2+ binding site [ion binding]; other site
1429244012637	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1429244012638	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244012639	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1429244012640	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1429244012641	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244012642	Sporulation inhibitor A; Region: Sda; pfam08970
1429244012643	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244012644	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1429244012645	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1429244012646	polyphosphate kinase; Provisional; Region: PRK05443
1429244012647	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1429244012648	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1429244012649	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
1429244012650	putative domain interface [polypeptide binding]; other site
1429244012651	putative active site [active]
1429244012652	catalytic site [active]
1429244012653	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1429244012654	putative domain interface [polypeptide binding]; other site
1429244012655	putative active site [active]
1429244012656	catalytic site [active]
1429244012657	hypothetical protein; Provisional; Region: PRK08236
1429244012658	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
1429244012659	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1429244012660	Uncharacterized conserved protein [Function unknown]; Region: COG3339
1429244012661	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1429244012662	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
1429244012663	putative sugar binding sites [chemical binding]; other site
1429244012664	Q-X-W motif; other site
1429244012665	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244012666	Interdomain contacts; other site
1429244012667	Cytokine receptor motif; other site
1429244012668	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1429244012669	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1429244012670	EamA-like transporter family; Region: EamA; pfam00892
1429244012671	EamA-like transporter family; Region: EamA; pfam00892
1429244012672	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244012673	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244012674	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244012675	dimerization interface [polypeptide binding]; other site
1429244012676	Predicted membrane protein [Function unknown]; Region: COG2323
1429244012677	Uncharacterized conserved protein [Function unknown]; Region: COG1633
1429244012678	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1429244012679	dinuclear metal binding motif [ion binding]; other site
1429244012680	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1429244012681	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244012682	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244012683	DNA binding residues [nucleotide binding]
1429244012684	Domain of unknown function (DUF1835); Region: DUF1835; pfam08874
1429244012685	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1429244012686	putative menaquinone biosynthesis protein, SCO4494 family; Region: mena_SCO4494; TIGR03700
1429244012687	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244012688	FeS/SAM binding site; other site
1429244012689	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1429244012690	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244012691	hypothetical protein; Provisional; Region: PRK13669
1429244012692	NifU-like domain; Region: NifU; cl00484
1429244012693	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK12825
1429244012694	classical (c) SDRs; Region: SDR_c; cd05233
1429244012695	NAD(P) binding site [chemical binding]; other site
1429244012696	active site
1429244012697	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1429244012698	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1429244012699	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244012700	conserved gate region; other site
1429244012701	ABC-ATPase subunit interface; other site
1429244012702	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1429244012703	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1429244012704	Walker A/P-loop; other site
1429244012705	ATP binding site [chemical binding]; other site
1429244012706	Q-loop/lid; other site
1429244012707	ABC transporter signature motif; other site
1429244012708	Walker B; other site
1429244012709	D-loop; other site
1429244012710	H-loop/switch region; other site
1429244012711	NIL domain; Region: NIL; pfam09383
1429244012712	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
1429244012713	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
1429244012714	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1429244012715	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
1429244012716	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244012717	catalytic residues [active]
1429244012718	Protein of unknown function (DUF2515); Region: DUF2515; pfam10720
1429244012719	stage V sporulation protein B; Region: spore_V_B; TIGR02900
1429244012720	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1429244012721	Protein of unknown function (DUF456); Region: DUF456; pfam04306
1429244012722	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244012723	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1429244012724	active site
1429244012725	motif I; other site
1429244012726	motif II; other site
1429244012727	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244012728	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1429244012729	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1429244012730	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1429244012731	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1429244012732	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1429244012733	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1429244012734	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1429244012735	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1429244012736	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244012737	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244012738	putative substrate translocation pore; other site
1429244012739	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1429244012740	active site
1429244012741	metal binding site [ion binding]; metal-binding site
1429244012742	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1429244012743	UbiA prenyltransferase family; Region: UbiA; pfam01040
1429244012744	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1429244012745	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1429244012746	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1429244012747	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1429244012748	active site
1429244012749	HIGH motif; other site
1429244012750	dimer interface [polypeptide binding]; other site
1429244012751	KMSKS motif; other site
1429244012752	T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244012753	aldose 1-epimerase superfamily; Region: Aldose_epim; cd01081
1429244012754	active site
1429244012755	catalytic residues [active]
1429244012756	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1429244012757	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
1429244012758	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1429244012759	active site
1429244012760	Zn binding site [ion binding]; other site
1429244012761	YycC-like protein; Region: YycC; pfam14174
1429244012762	Uncharacterized protein conserved in bacteria (DUF2225); Region: DUF2225; pfam09986
1429244012763	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655
1429244012764	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
1429244012765	apolar tunnel; other site
1429244012766	heme binding site [chemical binding]; other site
1429244012767	dimerization interface [polypeptide binding]; other site
1429244012768	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
1429244012769	Nucleoside recognition; Region: Gate; pfam07670
1429244012770	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
1429244012771	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1429244012772	Protein of unknown function (DUF1027); Region: DUF1027; pfam06265
1429244012773	lipoyl synthase; Provisional; Region: PRK05481
1429244012774	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244012775	FeS/SAM binding site; other site
1429244012776	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1429244012777	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244012778	Sporulation protein YunB (Spo_YunB); Region: Spore_YunB; cl09783
1429244012779	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244012780	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244012781	active site
1429244012782	catalytic tetrad [active]
1429244012783	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244012784	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244012785	dimer interface [polypeptide binding]; other site
1429244012786	conserved gate region; other site
1429244012787	putative PBP binding loops; other site
1429244012788	ABC-ATPase subunit interface; other site
1429244012789	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244012790	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244012791	dimer interface [polypeptide binding]; other site
1429244012792	conserved gate region; other site
1429244012793	putative PBP binding loops; other site
1429244012794	ABC-ATPase subunit interface; other site
1429244012795	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244012796	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244012797	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244012798	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244012799	dimerization interface [polypeptide binding]; other site
1429244012800	Histidine kinase; Region: His_kinase; pfam06580
1429244012801	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244012802	ATP binding site [chemical binding]; other site
1429244012803	Mg2+ binding site [ion binding]; other site
1429244012804	G-X-G motif; other site
1429244012805	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244012806	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244012807	active site
1429244012808	phosphorylation site [posttranslational modification]
1429244012809	intermolecular recognition site; other site
1429244012810	dimerization interface [polypeptide binding]; other site
1429244012811	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244012812	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244012813	A new structural DNA glycosylase; Region: AlkD_like; cd06561
1429244012814	active site
1429244012815	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1429244012816	endonuclease III; Region: ENDO3c; smart00478
1429244012817	minor groove reading motif; other site
1429244012818	helix-hairpin-helix signature motif; other site
1429244012819	substrate binding pocket [chemical binding]; other site
1429244012820	active site
1429244012821	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1429244012822	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244012823	FeS/SAM binding site; other site
1429244012824	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1429244012825	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1429244012826	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1429244012827	DNA binding site [nucleotide binding]
1429244012828	active site
1429244012829	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1429244012830	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1429244012831	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244012832	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244012833	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1429244012834	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1429244012835	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1429244012836	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1429244012837	active site turn [active]
1429244012838	phosphorylation site [posttranslational modification]
1429244012839	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1429244012840	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1429244012841	HPr interaction site; other site
1429244012842	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244012843	active site
1429244012844	phosphorylation site [posttranslational modification]
1429244012845	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244012846	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244012847	PRD domain; Region: PRD; pfam00874
1429244012848	PRD domain; Region: PRD; pfam00874
1429244012849	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1429244012850	beta-galactosidase; Region: BGL; TIGR03356
1429244012851	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1429244012852	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1429244012853	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1429244012854	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1429244012855	TrkA-N domain; Region: TrkA_N; pfam02254
1429244012856	TrkA-C domain; Region: TrkA_C; pfam02080
1429244012857	Small, acid-soluble spore protein I; Region: SSPI; cl07940
1429244012858	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1429244012859	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1429244012860	G1 box; other site
1429244012861	putative GEF interaction site [polypeptide binding]; other site
1429244012862	GTP/Mg2+ binding site [chemical binding]; other site
1429244012863	Switch I region; other site
1429244012864	G2 box; other site
1429244012865	G3 box; other site
1429244012866	Switch II region; other site
1429244012867	G4 box; other site
1429244012868	G5 box; other site
1429244012869	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1429244012870	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1429244012871	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1429244012872	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1429244012873	Protein of unknown function (DUF1779); Region: DUF1779; pfam08680
1429244012874	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244012875	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244012876	DNA binding residues [nucleotide binding]
1429244012877	dimerization interface [polypeptide binding]; other site
1429244012878	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1429244012879	Histidine kinase; Region: HisKA_3; pfam07730
1429244012880	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244012881	ATP binding site [chemical binding]; other site
1429244012882	Mg2+ binding site [ion binding]; other site
1429244012883	G-X-G motif; other site
1429244012884	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
1429244012885	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1429244012886	PspC domain; Region: PspC; pfam04024
1429244012887	PspA/IM30 family; Region: PspA_IM30; pfam04012
1429244012888	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244012889	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244012890	putative substrate translocation pore; other site
1429244012891	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244012892	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244012893	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1429244012894	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1429244012895	FeS assembly protein SufB; Region: sufB; TIGR01980
1429244012896	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
1429244012897	FeS assembly protein SufD; Region: sufD; TIGR01981
1429244012898	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1429244012899	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1429244012900	Walker A/P-loop; other site
1429244012901	ATP binding site [chemical binding]; other site
1429244012902	Q-loop/lid; other site
1429244012903	ABC transporter signature motif; other site
1429244012904	Walker B; other site
1429244012905	D-loop; other site
1429244012906	H-loop/switch region; other site
1429244012907	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244012908	MarR family; Region: MarR; pfam01047
1429244012909	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1429244012910	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244012911	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1429244012912	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1429244012913	active site
1429244012914	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1429244012915	metal binding site 2 [ion binding]; metal-binding site
1429244012916	putative DNA binding helix; other site
1429244012917	metal binding site 1 [ion binding]; metal-binding site
1429244012918	dimer interface [polypeptide binding]; other site
1429244012919	structural Zn2+ binding site [ion binding]; other site
1429244012920	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
1429244012921	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1429244012922	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1429244012923	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1429244012924	MgtC family; Region: MgtC; pfam02308
1429244012925	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244012926	Coenzyme A binding pocket [chemical binding]; other site
1429244012927	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1429244012928	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1429244012929	GatB domain; Region: GatB_Yqey; smart00845
1429244012930	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1429244012931	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1429244012932	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1429244012933	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1429244012934	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1429244012935	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1429244012936	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1429244012937	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244012938	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244012939	S-adenosylmethionine binding site [chemical binding]; other site
1429244012940	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1429244012941	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
1429244012942	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1429244012943	Protein of unknown function (DUF1256); Region: DUF1256; cl06087
1429244012944	Protein of unknown function (DUF1128); Region: DUF1128; cl11553
1429244012945	Pirin-related protein [General function prediction only]; Region: COG1741
1429244012946	Pirin; Region: Pirin; pfam02678
1429244012947	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
1429244012948	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1429244012949	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1429244012950	active site
1429244012951	Escherichia coli CorA-Salmonella typhimurium ZntB_like family; Region: EcCorA_ZntB-like; cd12821
1429244012952	Cl binding site [ion binding]; other site
1429244012953	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1429244012954	oligomer interface [polypeptide binding]; other site
1429244012955	RNA polymerase sigma factor SigB; Validated; Region: PRK08583
1429244012956	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244012957	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1429244012958	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1429244012959	DNA binding residues [nucleotide binding]
1429244012960	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1429244012961	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244012962	ATP binding site [chemical binding]; other site
1429244012963	Mg2+ binding site [ion binding]; other site
1429244012964	G-X-G motif; other site
1429244012965	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1429244012966	anti sigma factor interaction site; other site
1429244012967	regulatory phosphorylation site [posttranslational modification]; other site
1429244012968	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244012969	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244012970	active site
1429244012971	phosphorylation site [posttranslational modification]
1429244012972	intermolecular recognition site; other site
1429244012973	dimerization interface [polypeptide binding]; other site
1429244012974	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244012975	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244012976	dimer interface [polypeptide binding]; other site
1429244012977	phosphorylation site [posttranslational modification]
1429244012978	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244012979	ATP binding site [chemical binding]; other site
1429244012980	Mg2+ binding site [ion binding]; other site
1429244012981	G-X-G motif; other site
1429244012982	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244012983	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244012984	active site
1429244012985	phosphorylation site [posttranslational modification]
1429244012986	intermolecular recognition site; other site
1429244012987	dimerization interface [polypeptide binding]; other site
1429244012988	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1429244012989	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1429244012990	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1429244012991	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1429244012992	HAMP domain; Region: HAMP; pfam00672
1429244012993	GAF domain; Region: GAF_3; pfam13492
1429244012994	GAF domain; Region: GAF_2; pfam13185
1429244012995	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244012996	dimer interface [polypeptide binding]; other site
1429244012997	phosphorylation site [posttranslational modification]
1429244012998	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244012999	ATP binding site [chemical binding]; other site
1429244013000	Mg2+ binding site [ion binding]; other site
1429244013001	G-X-G motif; other site
1429244013002	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244013003	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013004	active site
1429244013005	phosphorylation site [posttranslational modification]
1429244013006	intermolecular recognition site; other site
1429244013007	dimerization interface [polypeptide binding]; other site
1429244013008	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1429244013009	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013010	active site
1429244013011	phosphorylation site [posttranslational modification]
1429244013012	intermolecular recognition site; other site
1429244013013	dimerization interface [polypeptide binding]; other site
1429244013014	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244013015	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013016	active site
1429244013017	phosphorylation site [posttranslational modification]
1429244013018	intermolecular recognition site; other site
1429244013019	dimerization interface [polypeptide binding]; other site
1429244013020	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244013021	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013022	active site
1429244013023	phosphorylation site [posttranslational modification]
1429244013024	intermolecular recognition site; other site
1429244013025	dimerization interface [polypeptide binding]; other site
1429244013026	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1429244013027	Heat induced stress protein YflT; Region: YflT; pfam11181
1429244013028	Bacterial protein of unknown function (DUF948); Region: DUF948; pfam06103
1429244013029	Bacterial SH3 domain; Region: SH3_3; pfam08239
1429244013030	Bacterial SH3 domain; Region: SH3_3; pfam08239
1429244013031	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1429244013032	NlpC/P60 family; Region: NLPC_P60; pfam00877
1429244013033	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1429244013034	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1429244013035	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1429244013036	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244013037	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244013038	ABC transporter; Region: ABC_tran_2; pfam12848
1429244013039	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244013040	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244013041	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244013042	Walker A/P-loop; other site
1429244013043	ATP binding site [chemical binding]; other site
1429244013044	Q-loop/lid; other site
1429244013045	ABC transporter signature motif; other site
1429244013046	Walker B; other site
1429244013047	D-loop; other site
1429244013048	H-loop/switch region; other site
1429244013049	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244013050	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244013051	dimer interface [polypeptide binding]; other site
1429244013052	ABC-ATPase subunit  interface; other site
1429244013053	putative PBP binding regions; other site
1429244013054	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244013055	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244013056	ABC-ATPase subunit  interface; other site
1429244013057	dimer interface [polypeptide binding]; other site
1429244013058	putative PBP binding regions; other site
1429244013059	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244013060	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
1429244013061	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244013062	intersubunit interface [polypeptide binding]; other site
1429244013063	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
1429244013064	heme-binding site [chemical binding]; other site
1429244013065	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
1429244013066	heme-binding site [chemical binding]; other site
1429244013067	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
1429244013068	heme-binding site [chemical binding]; other site
1429244013069	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1429244013070	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1429244013071	intersubunit interface [polypeptide binding]; other site
1429244013072	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1429244013073	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244013074	ABC-ATPase subunit  interface; other site
1429244013075	dimer interface [polypeptide binding]; other site
1429244013076	putative PBP binding regions; other site
1429244013077	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244013078	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244013079	Walker A/P-loop; other site
1429244013080	ATP binding site [chemical binding]; other site
1429244013081	Q-loop/lid; other site
1429244013082	ABC transporter signature motif; other site
1429244013083	Walker B; other site
1429244013084	D-loop; other site
1429244013085	H-loop/switch region; other site
1429244013086	heme-degrading monooxygenase IsdG; Provisional; Region: PRK13314
1429244013087	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1429244013088	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1429244013089	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1429244013090	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1429244013091	MarR family; Region: MarR_2; cl17246
1429244013092	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244013093	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244013094	putative substrate translocation pore; other site
1429244013095	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; smart00932
1429244013096	Virulence factor; Region: Virulence_fact; pfam13769
1429244013097	HEAT repeats; Region: HEAT_2; pfam13646
1429244013098	HEAT repeats; Region: HEAT_2; pfam13646
1429244013099	E-Z type HEAT repeats; Region: EZ_HEAT; smart00567
1429244013100	lysine transporter; Provisional; Region: PRK10836
1429244013101	H+ Antiporter protein; Region: 2A0121; TIGR00900
1429244013102	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1429244013103	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1429244013104	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1429244013105	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1429244013106	G1 box; other site
1429244013107	GTP/Mg2+ binding site [chemical binding]; other site
1429244013108	Switch I region; other site
1429244013109	G2 box; other site
1429244013110	G3 box; other site
1429244013111	Switch II region; other site
1429244013112	G4 box; other site
1429244013113	G5 box; other site
1429244013114	Nucleoside recognition; Region: Gate; pfam07670
1429244013115	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1429244013116	Nucleoside recognition; Region: Gate; pfam07670
1429244013117	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1429244013118	N- and C-terminal domain interface [polypeptide binding]; other site
1429244013119	D-xylulose kinase; Region: XylB; TIGR01312
1429244013120	active site
1429244013121	MgATP binding site [chemical binding]; other site
1429244013122	catalytic site [active]
1429244013123	metal binding site [ion binding]; metal-binding site
1429244013124	xylulose binding site [chemical binding]; other site
1429244013125	homodimer interface [polypeptide binding]; other site
1429244013126	xylose isomerase; Provisional; Region: PRK05474
1429244013127	xylose isomerase; Region: xylose_isom_A; TIGR02630
1429244013128	MarR family; Region: MarR_2; pfam12802
1429244013129	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1429244013130	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1429244013131	nucleotide binding site [chemical binding]; other site
1429244013132	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1429244013133	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1429244013134	beta-galactosidase; Region: BGL; TIGR03356
1429244013135	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1429244013136	CAT RNA binding domain; Region: CAT_RBD; smart01061
1429244013137	PRD domain; Region: PRD; pfam00874
1429244013138	PRD domain; Region: PRD; pfam00874
1429244013139	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1429244013140	HPr interaction site; other site
1429244013141	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1429244013142	active site
1429244013143	phosphorylation site [posttranslational modification]
1429244013144	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1429244013145	catalytic residues [active]
1429244013146	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1429244013147	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1429244013148	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244013149	ZIP Zinc transporter; Region: Zip; pfam02535
1429244013150	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
1429244013151	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1429244013152	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244013153	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1429244013154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244013155	putative substrate translocation pore; other site
1429244013156	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1429244013157	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1429244013158	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1429244013159	motif II; other site
1429244013160	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1429244013161	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1429244013162	metal-binding site [ion binding]
1429244013163	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1429244013164	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1429244013165	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1429244013166	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244013167	dimerization interface [polypeptide binding]; other site
1429244013168	putative DNA binding site [nucleotide binding]; other site
1429244013169	putative Zn2+ binding site [ion binding]; other site
1429244013170	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244013171	Old yellow enzyme (OYE)-related FMN binding domain, group 5.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_5_FMN; cd04747
1429244013172	putative active site [active]
1429244013173	putative FMN binding site [chemical binding]; other site
1429244013174	putative substrate binding site [chemical binding]; other site
1429244013175	putative catalytic residue [active]
1429244013176	cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847
1429244013177	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1429244013178	Subunit I/III interface [polypeptide binding]; other site
1429244013179	Subunit III/IV interface [polypeptide binding]; other site
1429244013180	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1429244013181	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1429244013182	D-pathway; other site
1429244013183	Putative ubiquinol binding site [chemical binding]; other site
1429244013184	Low-spin heme (heme b) binding site [chemical binding]; other site
1429244013185	Putative water exit pathway; other site
1429244013186	Binuclear center (heme o3/CuB) [ion binding]; other site
1429244013187	K-pathway; other site
1429244013188	Putative proton exit pathway; other site
1429244013189	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1429244013190	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1429244013191	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1429244013192	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
1429244013193	beta-galactosidase; Region: BGL; TIGR03356
1429244013194	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244013195	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244013196	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244013197	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013198	dimer interface [polypeptide binding]; other site
1429244013199	conserved gate region; other site
1429244013200	putative PBP binding loops; other site
1429244013201	ABC-ATPase subunit interface; other site
1429244013202	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244013203	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013204	dimer interface [polypeptide binding]; other site
1429244013205	conserved gate region; other site
1429244013206	putative PBP binding loops; other site
1429244013207	ABC-ATPase subunit interface; other site
1429244013208	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1429244013209	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
1429244013210	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1429244013211	Walker A/P-loop; other site
1429244013212	ATP binding site [chemical binding]; other site
1429244013213	Q-loop/lid; other site
1429244013214	ABC transporter signature motif; other site
1429244013215	Walker B; other site
1429244013216	D-loop; other site
1429244013217	H-loop/switch region; other site
1429244013218	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1429244013219	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244013220	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244013221	Walker A/P-loop; other site
1429244013222	ATP binding site [chemical binding]; other site
1429244013223	Q-loop/lid; other site
1429244013224	ABC transporter signature motif; other site
1429244013225	Walker B; other site
1429244013226	D-loop; other site
1429244013227	H-loop/switch region; other site
1429244013228	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1429244013229	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1429244013230	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1429244013231	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1429244013232	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013233	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244013234	active site
1429244013235	phosphorylation site [posttranslational modification]
1429244013236	intermolecular recognition site; other site
1429244013237	dimerization interface [polypeptide binding]; other site
1429244013238	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244013239	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244013240	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244013241	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244013242	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244013243	dimerization interface [polypeptide binding]; other site
1429244013244	Histidine kinase; Region: His_kinase; pfam06580
1429244013245	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244013246	ATP binding site [chemical binding]; other site
1429244013247	Mg2+ binding site [ion binding]; other site
1429244013248	G-X-G motif; other site
1429244013249	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1429244013250	active site
1429244013251	catalytic residues [active]
1429244013252	metal binding site [ion binding]; metal-binding site
1429244013253	Uncharacterized proteins similar to Bacillus subtilis YncM; Region: YncM_like; cd13427
1429244013254	putative binding site; other site
1429244013255	putative dimer interface [polypeptide binding]; other site
1429244013256	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1429244013257	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244013258	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244013259	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1429244013260	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
1429244013261	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1429244013262	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1429244013263	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244013264	active site
1429244013265	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
1429244013266	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1429244013267	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244013268	active site
1429244013269	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244013270	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
1429244013271	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1429244013272	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1429244013273	Domain of unknown function DUF21; Region: DUF21; pfam01595
1429244013274	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1429244013275	Transporter associated domain; Region: CorC_HlyC; cl08393
1429244013276	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1429244013277	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1429244013278	catalytic residues [active]
1429244013279	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244013280	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244013281	active site
1429244013282	catalytic tetrad [active]
1429244013283	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1429244013284	Putative esterase; Region: Esterase; pfam00756
1429244013285	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1429244013286	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
1429244013287	putative ligand binding residues [chemical binding]; other site
1429244013288	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1429244013289	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244013290	Walker A/P-loop; other site
1429244013291	ATP binding site [chemical binding]; other site
1429244013292	Q-loop/lid; other site
1429244013293	ABC transporter signature motif; other site
1429244013294	Walker B; other site
1429244013295	D-loop; other site
1429244013296	H-loop/switch region; other site
1429244013297	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244013298	ABC-ATPase subunit  interface; other site
1429244013299	dimer interface [polypeptide binding]; other site
1429244013300	putative PBP binding regions; other site
1429244013301	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1429244013302	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1429244013303	ABC-ATPase subunit  interface; other site
1429244013304	dimer interface [polypeptide binding]; other site
1429244013305	putative PBP binding regions; other site
1429244013306	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244013307	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013308	active site
1429244013309	phosphorylation site [posttranslational modification]
1429244013310	intermolecular recognition site; other site
1429244013311	dimerization interface [polypeptide binding]; other site
1429244013312	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244013313	DNA binding site [nucleotide binding]
1429244013314	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244013315	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1429244013316	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244013317	ATP binding site [chemical binding]; other site
1429244013318	Mg2+ binding site [ion binding]; other site
1429244013319	G-X-G motif; other site
1429244013320	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244013321	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1429244013322	Walker A/P-loop; other site
1429244013323	ATP binding site [chemical binding]; other site
1429244013324	Q-loop/lid; other site
1429244013325	ABC transporter signature motif; other site
1429244013326	Walker B; other site
1429244013327	D-loop; other site
1429244013328	H-loop/switch region; other site
1429244013329	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1429244013330	FtsX-like permease family; Region: FtsX; pfam02687
1429244013331	FtsX-like permease family; Region: FtsX; pfam02687
1429244013332	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1429244013333	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244013334	putative DNA binding site [nucleotide binding]; other site
1429244013335	putative Zn2+ binding site [ion binding]; other site
1429244013336	AsnC family; Region: AsnC_trans_reg; pfam01037
1429244013337	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244013338	putative substrate translocation pore; other site
1429244013339	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244013340	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244013341	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244013342	Coenzyme A binding pocket [chemical binding]; other site
1429244013343	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244013344	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244013345	Coenzyme A binding pocket [chemical binding]; other site
1429244013346	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1429244013347	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244013348	Zn binding site [ion binding]; other site
1429244013349	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1429244013350	Zn binding site [ion binding]; other site
1429244013351	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
1429244013352	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
1429244013353	active site
1429244013354	Zn binding site [ion binding]; other site
1429244013355	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1429244013356	dimer interface [polypeptide binding]; other site
1429244013357	substrate binding site [chemical binding]; other site
1429244013358	ATP binding site [chemical binding]; other site
1429244013359	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1429244013360	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1429244013361	active site
1429244013362	metal binding site [ion binding]; metal-binding site
1429244013363	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1429244013364	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1429244013365	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244013366	membrane-bound complex binding site; other site
1429244013367	hinge residues; other site
1429244013368	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
1429244013369	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1429244013370	Walker A/P-loop; other site
1429244013371	ATP binding site [chemical binding]; other site
1429244013372	Q-loop/lid; other site
1429244013373	ABC transporter signature motif; other site
1429244013374	Walker B; other site
1429244013375	D-loop; other site
1429244013376	H-loop/switch region; other site
1429244013377	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1429244013378	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013379	dimer interface [polypeptide binding]; other site
1429244013380	conserved gate region; other site
1429244013381	ABC-ATPase subunit interface; other site
1429244013382	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1429244013383	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013384	dimer interface [polypeptide binding]; other site
1429244013385	conserved gate region; other site
1429244013386	putative PBP binding loops; other site
1429244013387	ABC-ATPase subunit interface; other site
1429244013388	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1429244013389	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244013390	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244013391	catalytic residue [active]
1429244013392	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013393	dimer interface [polypeptide binding]; other site
1429244013394	conserved gate region; other site
1429244013395	putative PBP binding loops; other site
1429244013396	ABC-ATPase subunit interface; other site
1429244013397	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1429244013398	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013399	dimer interface [polypeptide binding]; other site
1429244013400	conserved gate region; other site
1429244013401	putative PBP binding loops; other site
1429244013402	ABC-ATPase subunit interface; other site
1429244013403	ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: Sbp; COG1613
1429244013404	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1429244013405	Putative periplasmic lipoprotein; Region: DUF1425; cl12345
1429244013406	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1429244013407	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
1429244013408	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1429244013409	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1429244013410	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1429244013411	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1429244013412	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1429244013413	phosphopentomutase; Provisional; Region: PRK05362
1429244013414	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1429244013415	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1429244013416	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1429244013417	Nucleoside recognition; Region: Gate; pfam07670
1429244013418	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1429244013419	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1429244013420	active site
1429244013421	catalytic motif [active]
1429244013422	Zn binding site [ion binding]; other site
1429244013423	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1429244013424	intersubunit interface [polypeptide binding]; other site
1429244013425	active site
1429244013426	catalytic residue [active]
1429244013427	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1429244013428	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244013429	DNA binding residues [nucleotide binding]
1429244013430	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1429244013431	CheW-like domain; Region: CheW; pfam01584
1429244013432	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1429244013433	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1429244013434	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1429244013435	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1429244013436	catalytic motif [active]
1429244013437	Zn binding site [ion binding]; other site
1429244013438	RibD C-terminal domain; Region: RibD_C; cl17279
1429244013439	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1429244013440	dimerization interface [polypeptide binding]; other site
1429244013441	active site
1429244013442	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1429244013443	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
1429244013444	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244013445	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244013446	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244013447	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244013448	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1429244013449	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1429244013450	conserved cys residue [active]
1429244013451	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1429244013452	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
1429244013453	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1429244013454	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1429244013455	Ligand Binding Site [chemical binding]; other site
1429244013456	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1429244013457	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244013458	putative substrate translocation pore; other site
1429244013459	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244013460	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244013461	non-specific DNA binding site [nucleotide binding]; other site
1429244013462	salt bridge; other site
1429244013463	sequence-specific DNA binding site [nucleotide binding]; other site
1429244013464	Cupin domain; Region: Cupin_2; pfam07883
1429244013465	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244013466	MarR family; Region: MarR; pfam01047
1429244013467	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1429244013468	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244013469	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244013470	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1429244013471	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1429244013472	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244013473	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244013474	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1429244013475	arsenical pump membrane protein; Provisional; Region: PRK15445
1429244013476	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1429244013477	transmembrane helices; other site
1429244013478	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244013479	dimerization interface [polypeptide binding]; other site
1429244013480	putative DNA binding site [nucleotide binding]; other site
1429244013481	putative Zn2+ binding site [ion binding]; other site
1429244013482	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1429244013483	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1429244013484	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1429244013485	Platelet-activating factor acetylhydrolase, isoform II; Region: PAF-AH_p_II; pfam03403
1429244013486	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244013487	sugar efflux transporter; Region: 2A0120; TIGR00899
1429244013488	putative substrate translocation pore; other site
1429244013489	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1429244013490	glycosyltransferase, MGT family; Region: MGT; TIGR01426
1429244013491	active site
1429244013492	TDP-binding site; other site
1429244013493	acceptor substrate-binding pocket; other site
1429244013494	homodimer interface [polypeptide binding]; other site
1429244013495	Pectate lyase; Region: Pec_lyase_C; cl01593
1429244013496	putative pectinesterase; Region: PLN02432; cl01911
1429244013497	Pectinesterase; Region: Pectinesterase; pfam01095
1429244013498	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244013499	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1429244013500	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244013501	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244013502	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1429244013503	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244013504	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244013505	catalytic residue [active]
1429244013506	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244013507	MarR family; Region: MarR_2; cl17246
1429244013508	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1429244013509	Cation efflux family; Region: Cation_efflux; cl00316
1429244013510	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1429244013511	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244013512	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244013513	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244013514	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013515	active site
1429244013516	phosphorylation site [posttranslational modification]
1429244013517	intermolecular recognition site; other site
1429244013518	dimerization interface [polypeptide binding]; other site
1429244013519	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244013520	DNA binding residues [nucleotide binding]
1429244013521	dimerization interface [polypeptide binding]; other site
1429244013522	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1429244013523	Histidine kinase; Region: HisKA_3; pfam07730
1429244013524	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244013525	ATP binding site [chemical binding]; other site
1429244013526	Mg2+ binding site [ion binding]; other site
1429244013527	G-X-G motif; other site
1429244013528	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1429244013529	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1429244013530	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244013531	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244013532	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244013533	Walker A/P-loop; other site
1429244013534	ATP binding site [chemical binding]; other site
1429244013535	Q-loop/lid; other site
1429244013536	ABC transporter signature motif; other site
1429244013537	Walker B; other site
1429244013538	D-loop; other site
1429244013539	H-loop/switch region; other site
1429244013540	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244013541	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244013542	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244013543	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013544	dimer interface [polypeptide binding]; other site
1429244013545	conserved gate region; other site
1429244013546	putative PBP binding loops; other site
1429244013547	ABC-ATPase subunit interface; other site
1429244013548	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244013549	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013550	dimer interface [polypeptide binding]; other site
1429244013551	conserved gate region; other site
1429244013552	putative PBP binding loops; other site
1429244013553	ABC-ATPase subunit interface; other site
1429244013554	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244013555	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_2; cd08498
1429244013556	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1429244013557	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1429244013558	metal binding site [ion binding]; metal-binding site
1429244013559	dimer interface [polypeptide binding]; other site
1429244013560	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1429244013561	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244013562	DNA-binding site [nucleotide binding]; DNA binding site
1429244013563	FCD domain; Region: FCD; pfam07729
1429244013564	Small acid-soluble spore protein H family; Region: SspH; pfam08141
1429244013565	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1429244013566	glycosyltransferase, MGT family; Region: MGT; TIGR01426
1429244013567	active site
1429244013568	TDP-binding site; other site
1429244013569	acceptor substrate-binding pocket; other site
1429244013570	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1429244013571	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1429244013572	substrate binding [chemical binding]; other site
1429244013573	active site
1429244013574	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1429244013575	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244013576	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013577	dimer interface [polypeptide binding]; other site
1429244013578	conserved gate region; other site
1429244013579	putative PBP binding loops; other site
1429244013580	ABC-ATPase subunit interface; other site
1429244013581	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244013582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244013583	dimer interface [polypeptide binding]; other site
1429244013584	conserved gate region; other site
1429244013585	putative PBP binding loops; other site
1429244013586	ABC-ATPase subunit interface; other site
1429244013587	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244013588	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1429244013589	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244013590	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244013591	DNA binding site [nucleotide binding]
1429244013592	domain linker motif; other site
1429244013593	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
1429244013594	dimerization interface [polypeptide binding]; other site
1429244013595	ligand binding site [chemical binding]; other site
1429244013596	sodium binding site [ion binding]; other site
1429244013597	Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]; Region: SKN1; COG2273
1429244013598	lichenase, member of glycosyl hydrolase family 16; Region: GH16_lichenase; cd02175
1429244013599	active site
1429244013600	active site
1429244013601	catalytic residues [active]
1429244013602	Fn3 associated; Region: Fn3_assoc; pfam13287
1429244013603	Fn3 associated; Region: Fn3_assoc; pfam13287
1429244013604	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_2; cd11339
1429244013605	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1429244013606	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_2; cd11339
1429244013607	active site
1429244013608	catalytic site [active]
1429244013609	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
1429244013610	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244013611	Predicted integral membrane protein [Function unknown]; Region: COG0392
1429244013612	Uncharacterized conserved protein [Function unknown]; Region: COG2898
1429244013613	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1429244013614	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1429244013615	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244013616	DNA binding residues [nucleotide binding]
1429244013617	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1429244013618	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1429244013619	FtsX-like permease family; Region: FtsX; pfam02687
1429244013620	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244013621	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1429244013622	Walker A/P-loop; other site
1429244013623	ATP binding site [chemical binding]; other site
1429244013624	Q-loop/lid; other site
1429244013625	ABC transporter signature motif; other site
1429244013626	Walker B; other site
1429244013627	D-loop; other site
1429244013628	H-loop/switch region; other site
1429244013629	HlyD family secretion protein; Region: HlyD_2; pfam12700
1429244013630	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244013631	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244013632	putative membrane fusion protein; Region: TIGR02828
1429244013633	Outer membrane efflux protein; Region: OEP; pfam02321
1429244013634	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1429244013635	active site
1429244013636	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244013637	S-adenosylmethionine binding site [chemical binding]; other site
1429244013638	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244013639	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013640	active site
1429244013641	phosphorylation site [posttranslational modification]
1429244013642	intermolecular recognition site; other site
1429244013643	dimerization interface [polypeptide binding]; other site
1429244013644	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244013645	DNA binding site [nucleotide binding]
1429244013646	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244013647	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244013648	dimerization interface [polypeptide binding]; other site
1429244013649	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244013650	dimer interface [polypeptide binding]; other site
1429244013651	phosphorylation site [posttranslational modification]
1429244013652	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244013653	ATP binding site [chemical binding]; other site
1429244013654	Mg2+ binding site [ion binding]; other site
1429244013655	G-X-G motif; other site
1429244013656	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1429244013657	Catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases; Region: CE4_NodB_like_3; cd10959
1429244013658	NodB motif; other site
1429244013659	putative active site [active]
1429244013660	putative catalytic site [active]
1429244013661	putative Zn binding site [ion binding]; other site
1429244013662	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
1429244013663	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
1429244013664	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1429244013665	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1429244013666	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1429244013667	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1429244013668	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1429244013669	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1429244013670	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1429244013671	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244013672	S-adenosylmethionine binding site [chemical binding]; other site
1429244013673	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244013674	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244013675	active site
1429244013676	phosphorylation site [posttranslational modification]
1429244013677	intermolecular recognition site; other site
1429244013678	dimerization interface [polypeptide binding]; other site
1429244013679	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244013680	DNA binding site [nucleotide binding]
1429244013681	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244013682	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244013683	dimerization interface [polypeptide binding]; other site
1429244013684	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244013685	dimer interface [polypeptide binding]; other site
1429244013686	phosphorylation site [posttranslational modification]
1429244013687	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244013688	ATP binding site [chemical binding]; other site
1429244013689	Mg2+ binding site [ion binding]; other site
1429244013690	G-X-G motif; other site
1429244013691	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244013692	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244013693	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1429244013694	Walker A/P-loop; other site
1429244013695	ATP binding site [chemical binding]; other site
1429244013696	Q-loop/lid; other site
1429244013697	ABC transporter signature motif; other site
1429244013698	Walker B; other site
1429244013699	D-loop; other site
1429244013700	H-loop/switch region; other site
1429244013701	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1429244013702	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1429244013703	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244013704	Walker A/P-loop; other site
1429244013705	ATP binding site [chemical binding]; other site
1429244013706	Q-loop/lid; other site
1429244013707	ABC transporter signature motif; other site
1429244013708	Walker B; other site
1429244013709	D-loop; other site
1429244013710	H-loop/switch region; other site
1429244013711	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244013712	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1429244013713	acyl-activating enzyme (AAE) consensus motif; other site
1429244013714	AMP binding site [chemical binding]; other site
1429244013715	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244013716	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1429244013717	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244013718	AMP binding site [chemical binding]; other site
1429244013719	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244013720	Condensation domain; Region: Condensation; pfam00668
1429244013721	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244013722	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244013723	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1429244013724	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244013725	Condensation domain; Region: Condensation; pfam00668
1429244013726	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244013727	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244013728	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1429244013729	acyl-activating enzyme (AAE) consensus motif; other site
1429244013730	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244013731	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1429244013732	acyl-activating enzyme (AAE) consensus motif; other site
1429244013733	AMP binding site [chemical binding]; other site
1429244013734	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244013735	Condensation domain; Region: Condensation; pfam00668
1429244013736	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244013737	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1429244013738	Condensation domain; Region: Condensation; pfam00668
1429244013739	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244013740	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1429244013741	acyl-activating enzyme (AAE) consensus motif; other site
1429244013742	AMP binding site [chemical binding]; other site
1429244013743	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1429244013744	Condensation domain; Region: Condensation; pfam00668
1429244013745	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1429244013746	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1429244013747	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1429244013748	acyl-activating enzyme (AAE) consensus motif; other site
1429244013749	active site
1429244013750	AMP binding site [chemical binding]; other site
1429244013751	CoA binding site [chemical binding]; other site
1429244013752	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244013753	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
1429244013754	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1429244013755	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244013756	non-specific DNA binding site [nucleotide binding]; other site
1429244013757	salt bridge; other site
1429244013758	sequence-specific DNA binding site [nucleotide binding]; other site
1429244013759	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1429244013760	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1429244013761	Ligand Binding Site [chemical binding]; other site
1429244013762	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244013763	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244013764	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1429244013765	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1429244013766	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1429244013767	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1429244013768	glutaminase active site [active]
1429244013769	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1429244013770	dimer interface [polypeptide binding]; other site
1429244013771	active site
1429244013772	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1429244013773	dimer interface [polypeptide binding]; other site
1429244013774	active site
1429244013775	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
1429244013776	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1429244013777	active site
1429244013778	substrate binding site [chemical binding]; other site
1429244013779	metal binding site [ion binding]; metal-binding site
1429244013780	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
1429244013781	YbbR-like protein; Region: YbbR; pfam07949
1429244013782	YbbR-like protein; Region: YbbR; pfam07949
1429244013783	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1429244013784	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1429244013785	Putative zinc-finger; Region: zf-HC2; pfam13490
1429244013786	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
1429244013787	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1429244013788	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
1429244013789	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244013790	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244013791	DNA binding residues [nucleotide binding]
1429244013792	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1429244013793	Phosphoenolpyruvate carboxylase; Region: PEPcase; pfam00311
1429244013794	Uncharacterized membrane protein [Function unknown]; Region: SpoIIM; COG1300
1429244013795	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1429244013796	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1429244013797	Domain of unknown function DUF59; Region: DUF59; pfam01883
1429244013798	cell division ATPase MinD, archaeal; Region: minD_arch; TIGR01969
1429244013799	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1429244013800	Walker A motif; other site
1429244013801	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1429244013802	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1429244013803	active site
1429244013804	metal binding site [ion binding]; metal-binding site
1429244013805	sulfate adenylyltransferase; Reviewed; Region: sat; PRK04149
1429244013806	ATP-sulfurylase; Region: ATPS; cd00517
1429244013807	active site
1429244013808	HXXH motif; other site
1429244013809	flexible loop; other site
1429244013810	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1429244013811	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1429244013812	Active Sites [active]
1429244013813	malate dehydrogenase; Provisional; Region: PRK13529
1429244013814	Phage holin protein (Holin_LLH); Region: Holin_LLH; cl09890
1429244013815	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cd00599
1429244013816	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1429244013817	active site
1429244013818	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244013819	Holin family; Region: Phage_holin_4; cl01989
1429244013820	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; cl01817
1429244013821	Baseplate J-like protein; Region: Baseplate_J; cl01294
1429244013822	Phage P2 GpU; Region: Phage_P2_GpU; cl01391
1429244013823	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1429244013824	Phage Tail Protein X; Region: Phage_tail_X; cl02088
1429244013825	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1429244013826	Phage tail tube protein FII; Region: Phage_tube; cl01390
1429244013827	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
1429244013828	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
1429244013829	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1429244013830	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1429244013831	Phage portal protein, lambda family; Region: Phage_portal_2; pfam05136
1429244013832	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
1429244013833	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
1429244013834	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
1429244013835	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1429244013836	thiosulfate reductase PhsA; Provisional; Region: PRK15488
1429244013837	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
1429244013838	Domain of unknown function (DUF771); Region: DUF771; cl09962
1429244013839	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1429244013840	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244013841	non-specific DNA binding site [nucleotide binding]; other site
1429244013842	salt bridge; other site
1429244013843	sequence-specific DNA binding site [nucleotide binding]; other site
1429244013844	Domain of unknown function (DUF955); Region: DUF955; cl01076
1429244013845	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1429244013846	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
1429244013847	Int/Topo IB signature motif; other site
1429244013848	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1429244013849	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1429244013850	23S rRNA interface [nucleotide binding]; other site
1429244013851	L3 interface [polypeptide binding]; other site
1429244013852	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1429244013853	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1429244013854	dimerization interface 3.5A [polypeptide binding]; other site
1429244013855	active site
1429244013856	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1429244013857	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1429244013858	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1429244013859	alphaNTD - beta interaction site [polypeptide binding]; other site
1429244013860	alphaNTD homodimer interface [polypeptide binding]; other site
1429244013861	alphaNTD - beta' interaction site [polypeptide binding]; other site
1429244013862	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1429244013863	30S ribosomal protein S11; Validated; Region: PRK05309
1429244013864	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1429244013865	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1429244013866	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1429244013867	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1429244013868	rRNA binding site [nucleotide binding]; other site
1429244013869	predicted 30S ribosome binding site; other site
1429244013870	KOW motif of Ribosomal Protein L14; Region: KOW_RPL14; cd06088
1429244013871	RNA binding site [nucleotide binding]; other site
1429244013872	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1429244013873	active site
1429244013874	adenylate kinase; Reviewed; Region: adk; PRK00279
1429244013875	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1429244013876	AMP-binding site [chemical binding]; other site
1429244013877	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1429244013878	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1429244013879	SecY translocase; Region: SecY; pfam00344
1429244013880	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1429244013881	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1429244013882	23S rRNA binding site [nucleotide binding]; other site
1429244013883	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1429244013884	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1429244013885	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1429244013886	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1429244013887	5S rRNA interface [nucleotide binding]; other site
1429244013888	L27 interface [polypeptide binding]; other site
1429244013889	23S rRNA interface [nucleotide binding]; other site
1429244013890	L5 interface [polypeptide binding]; other site
1429244013891	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1429244013892	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1429244013893	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1429244013894	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1429244013895	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1429244013896	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1429244013897	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1429244013898	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1429244013899	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1429244013900	RNA binding site [nucleotide binding]; other site
1429244013901	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1429244013902	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1429244013903	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1429244013904	23S rRNA interface [nucleotide binding]; other site
1429244013905	putative translocon interaction site; other site
1429244013906	signal recognition particle (SRP54) interaction site; other site
1429244013907	L23 interface [polypeptide binding]; other site
1429244013908	trigger factor interaction site; other site
1429244013909	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1429244013910	23S rRNA interface [nucleotide binding]; other site
1429244013911	5S rRNA interface [nucleotide binding]; other site
1429244013912	putative antibiotic binding site [chemical binding]; other site
1429244013913	L25 interface [polypeptide binding]; other site
1429244013914	L27 interface [polypeptide binding]; other site
1429244013915	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1429244013916	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1429244013917	G-X-X-G motif; other site
1429244013918	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1429244013919	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1429244013920	putative translocon binding site; other site
1429244013921	protein-rRNA interface [nucleotide binding]; other site
1429244013922	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1429244013923	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1429244013924	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1429244013925	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1429244013926	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1429244013927	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1429244013928	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1429244013929	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1429244013930	elongation factor Tu; Reviewed; Region: PRK00049
1429244013931	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1429244013932	G1 box; other site
1429244013933	GEF interaction site [polypeptide binding]; other site
1429244013934	GTP/Mg2+ binding site [chemical binding]; other site
1429244013935	Switch I region; other site
1429244013936	G2 box; other site
1429244013937	G3 box; other site
1429244013938	Switch II region; other site
1429244013939	G4 box; other site
1429244013940	G5 box; other site
1429244013941	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1429244013942	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1429244013943	Antibiotic Binding Site [chemical binding]; other site
1429244013944	elongation factor G; Reviewed; Region: PRK00007
1429244013945	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1429244013946	G1 box; other site
1429244013947	putative GEF interaction site [polypeptide binding]; other site
1429244013948	GTP/Mg2+ binding site [chemical binding]; other site
1429244013949	Switch I region; other site
1429244013950	G2 box; other site
1429244013951	G3 box; other site
1429244013952	Switch II region; other site
1429244013953	G4 box; other site
1429244013954	G5 box; other site
1429244013955	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1429244013956	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1429244013957	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1429244013958	30S ribosomal protein S7; Validated; Region: PRK05302
1429244013959	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1429244013960	S17 interaction site [polypeptide binding]; other site
1429244013961	S8 interaction site; other site
1429244013962	16S rRNA interaction site [nucleotide binding]; other site
1429244013963	streptomycin interaction site [chemical binding]; other site
1429244013964	23S rRNA interaction site [nucleotide binding]; other site
1429244013965	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1429244013966	putative ribosomal protein L7Ae-like; Provisional; Region: PRK13602
1429244013967	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1429244013968	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1429244013969	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1429244013970	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1429244013971	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1429244013972	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1429244013973	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1429244013974	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1429244013975	G-loop; other site
1429244013976	DNA binding site [nucleotide binding]
1429244013977	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1429244013978	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1429244013979	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1429244013980	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1429244013981	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1429244013982	RPB10 interaction site [polypeptide binding]; other site
1429244013983	RPB1 interaction site [polypeptide binding]; other site
1429244013984	RPB11 interaction site [polypeptide binding]; other site
1429244013985	RPB3 interaction site [polypeptide binding]; other site
1429244013986	RPB12 interaction site [polypeptide binding]; other site
1429244013987	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244013988	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244013989	S-adenosylmethionine binding site [chemical binding]; other site
1429244013990	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1429244013991	core dimer interface [polypeptide binding]; other site
1429244013992	peripheral dimer interface [polypeptide binding]; other site
1429244013993	L10 interface [polypeptide binding]; other site
1429244013994	L11 interface [polypeptide binding]; other site
1429244013995	putative EF-Tu interaction site [polypeptide binding]; other site
1429244013996	putative EF-G interaction site [polypeptide binding]; other site
1429244013997	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1429244013998	23S rRNA interface [nucleotide binding]; other site
1429244013999	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1429244014000	L10 leader; Derived by automated computational analysis using gene prediction method: cmsearch.
1429244014001	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1429244014002	mRNA/rRNA interface [nucleotide binding]; other site
1429244014003	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1429244014004	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1429244014005	23S rRNA interface [nucleotide binding]; other site
1429244014006	L7/L12 interface [polypeptide binding]; other site
1429244014007	putative thiostrepton binding site; other site
1429244014008	L25 interface [polypeptide binding]; other site
1429244014009	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1429244014010	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1429244014011	putative homodimer interface [polypeptide binding]; other site
1429244014012	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1429244014013	heterodimer interface [polypeptide binding]; other site
1429244014014	homodimer interface [polypeptide binding]; other site
1429244014015	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1429244014016	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1429244014017	RNA polymerase factor sigma-70; Validated; Region: PRK08295
1429244014018	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244014019	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1429244014020	YacP-like NYN domain; Region: NYN_YacP; pfam05991
1429244014021	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1429244014022	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1429244014023	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1429244014024	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1429244014025	active site
1429244014026	metal binding site [ion binding]; metal-binding site
1429244014027	dimerization interface [polypeptide binding]; other site
1429244014028	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1429244014029	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1429244014030	active site
1429244014031	HIGH motif; other site
1429244014032	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1429244014033	KMSKS motif; other site
1429244014034	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1429244014035	tRNA binding surface [nucleotide binding]; other site
1429244014036	anticodon binding site; other site
1429244014037	serine O-acetyltransferase; Region: cysE; TIGR01172
1429244014038	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1429244014039	trimer interface [polypeptide binding]; other site
1429244014040	active site
1429244014041	substrate binding site [chemical binding]; other site
1429244014042	CoA binding site [chemical binding]; other site
1429244014043	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1429244014044	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1429244014045	HIGH motif; other site
1429244014046	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1429244014047	active site
1429244014048	KMSKS motif; other site
1429244014049	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1429244014050	homotrimer interaction site [polypeptide binding]; other site
1429244014051	zinc binding site [ion binding]; other site
1429244014052	CDP-binding sites; other site
1429244014053	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1429244014054	substrate binding site; other site
1429244014055	dimer interface; other site
1429244014056	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
1429244014057	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
1429244014058	putative active site [active]
1429244014059	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1429244014060	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
1429244014061	DNA integrity scanning protein DisA; Provisional; Region: PRK13482
1429244014062	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1429244014063	DisA bacterial checkpoint controller linker region; Region: DisA-linker; pfam10635
1429244014064	DNA repair protein RadA; Provisional; Region: PRK11823
1429244014065	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1429244014066	Walker A motif/ATP binding site; other site
1429244014067	ATP binding site [chemical binding]; other site
1429244014068	Walker B motif; other site
1429244014069	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1429244014070	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1429244014071	Clp amino terminal domain; Region: Clp_N; pfam02861
1429244014072	Clp amino terminal domain; Region: Clp_N; pfam02861
1429244014073	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244014074	Walker A motif; other site
1429244014075	ATP binding site [chemical binding]; other site
1429244014076	Walker B motif; other site
1429244014077	arginine finger; other site
1429244014078	UvrB/uvrC motif; Region: UVR; pfam02151
1429244014079	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1429244014080	Walker A motif; other site
1429244014081	ATP binding site [chemical binding]; other site
1429244014082	Walker B motif; other site
1429244014083	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1429244014084	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
1429244014085	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
1429244014086	ADP binding site [chemical binding]; other site
1429244014087	phosphagen binding site; other site
1429244014088	substrate specificity loop; other site
1429244014089	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1429244014090	UvrB/uvrC motif; Region: UVR; pfam02151
1429244014091	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
1429244014092	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
1429244014093	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
1429244014094	Coenzyme A binding pocket [chemical binding]; other site
1429244014095	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1429244014096	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1429244014097	nucleotide binding pocket [chemical binding]; other site
1429244014098	K-X-D-G motif; other site
1429244014099	catalytic site [active]
1429244014100	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1429244014101	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1429244014102	Dimer interface [polypeptide binding]; other site
1429244014103	BRCT sequence motif; other site
1429244014104	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1429244014105	Part of AAA domain; Region: AAA_19; pfam13245
1429244014106	Family description; Region: UvrD_C_2; pfam13538
1429244014107	PcrB family; Region: PcrB; pfam01884
1429244014108	PcrB_like proteins. One member of this family, a protein from Archaeoglobus fulgidus, has been characterized as a (S)-3-O-geranylgeranylglyceryl phosphate synthase (AfGGGPS). AfGGGPS catalyzes the formation of an ether linkage between...; Region: PcrB_like; cd02812
1429244014109	substrate binding site [chemical binding]; other site
1429244014110	putative active site [active]
1429244014111	dimer interface [polypeptide binding]; other site
1429244014112	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1429244014113	Uncharacterized hypothetical proteins similar to the catalytic domains of Phosphoinositide-specific phospholipaseand Glycerophosphodiester phosphodiesterases; Region: PI-PLCc_GDPD_SF_unchar1; cd08583
1429244014114	putative active site [active]
1429244014115	catalytic site [active]
1429244014116	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
1429244014117	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1429244014118	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1429244014119	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1429244014120	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1429244014121	Probable Catalytic site; other site
1429244014122	metal-binding site
1429244014123	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1429244014124	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1429244014125	NADP binding site [chemical binding]; other site
1429244014126	active site
1429244014127	putative substrate binding site [chemical binding]; other site
1429244014128	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1429244014129	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1429244014130	NAD binding site [chemical binding]; other site
1429244014131	substrate binding site [chemical binding]; other site
1429244014132	homodimer interface [polypeptide binding]; other site
1429244014133	active site
1429244014134	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1429244014135	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1429244014136	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1429244014137	substrate binding site; other site
1429244014138	tetramer interface; other site
1429244014139	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1429244014140	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1429244014141	inhibitor-cofactor binding pocket; inhibition site
1429244014142	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244014143	catalytic residue [active]
1429244014144	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1429244014145	putative formyltransferase; Provisional; Region: PRK06988
1429244014146	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1429244014147	active site
1429244014148	cosubstrate binding site; other site
1429244014149	substrate binding site [chemical binding]; other site
1429244014150	catalytic site [active]
1429244014151	Carboxy-terminal domain of Formyltransferase and similar domains; Region: FMT_C_like; cd08370
1429244014152	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1429244014153	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1429244014154	Ligand binding site; other site
1429244014155	Putative Catalytic site; other site
1429244014156	DXD motif; other site
1429244014157	Glucosyl transferase GtrII; Region: Glucos_trans_II; cl10304
1429244014158	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1429244014159	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1429244014160	active site
1429244014161	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244014162	active site
1429244014163	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
1429244014164	putative ligand binding site [chemical binding]; other site
1429244014165	putative catalytic site [active]
1429244014166	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1429244014167	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244014168	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244014169	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1429244014170	Walker A/P-loop; other site
1429244014171	ATP binding site [chemical binding]; other site
1429244014172	Q-loop/lid; other site
1429244014173	ABC transporter signature motif; other site
1429244014174	Walker B; other site
1429244014175	D-loop; other site
1429244014176	H-loop/switch region; other site
1429244014177	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
1429244014178	putative carbohydrate binding site [chemical binding]; other site
1429244014179	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1429244014180	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1429244014181	O-Antigen ligase; Region: Wzy_C; pfam04932
1429244014182	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1429244014183	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244014184	TPR motif; other site
1429244014185	binding surface
1429244014186	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1429244014187	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1429244014188	active site
1429244014189	tetramer interface; other site
1429244014190	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1429244014191	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1429244014192	Peptidase family U32; Region: Peptidase_U32; pfam01136
1429244014193	Collagenase; Region: DUF3656; pfam12392
1429244014194	Peptidase family U32; Region: Peptidase_U32; cl03113
1429244014195	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244014196	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244014197	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1429244014198	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1429244014199	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1429244014200	ferredoxin-nitrite reductase; Reviewed; Region: nirA; PRK09566
1429244014201	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1429244014202	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1429244014203	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1429244014204	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1429244014205	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1429244014206	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1429244014207	excinuclease ABC subunit B; Provisional; Region: PRK05298
1429244014208	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244014209	ATP binding site [chemical binding]; other site
1429244014210	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244014211	nucleotide binding region [chemical binding]; other site
1429244014212	ATP-binding site [chemical binding]; other site
1429244014213	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1429244014214	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1429244014215	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1429244014216	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1429244014217	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1429244014218	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1429244014219	ligand binding site [chemical binding]; other site
1429244014220	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1429244014221	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244014222	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244014223	non-specific DNA binding site [nucleotide binding]; other site
1429244014224	salt bridge; other site
1429244014225	sequence-specific DNA binding site [nucleotide binding]; other site
1429244014226	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1429244014227	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1429244014228	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244014229	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244014230	DNA binding residues [nucleotide binding]
1429244014231	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1429244014232	Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891
1429244014233	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1429244014234	Interdomain contacts; other site
1429244014235	Cytokine receptor motif; other site
1429244014236	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
1429244014237	putative metal binding site [ion binding]; other site
1429244014238	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
1429244014239	Cellulose binding domain; Region: CBM_3; pfam00942
1429244014240	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244014241	S-adenosylmethionine binding site [chemical binding]; other site
1429244014242	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1429244014243	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1429244014244	C-terminal peptidase (prc); Region: prc; TIGR00225
1429244014245	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1429244014246	protein binding site [polypeptide binding]; other site
1429244014247	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1429244014248	Catalytic dyad [active]
1429244014249	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1429244014250	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1429244014251	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1429244014252	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244014253	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1429244014254	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1429244014255	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1429244014256	ATP-binding cassette domain of the cell division transporter; Region: ABC_FtsE_transporter; cd03292
1429244014257	Walker A/P-loop; other site
1429244014258	ATP binding site [chemical binding]; other site
1429244014259	Q-loop/lid; other site
1429244014260	ABC transporter signature motif; other site
1429244014261	Walker B; other site
1429244014262	D-loop; other site
1429244014263	H-loop/switch region; other site
1429244014264	Uncharacterized vancomycin resistance protein [Defense mechanisms]; Region: COG2720
1429244014265	VanW like protein; Region: VanW; pfam04294
1429244014266	G5 domain; Region: G5; pfam07501
1429244014267	S-layer homology domain; Region: SLH; pfam00395
1429244014268	S-layer homology domain; Region: SLH; pfam00395
1429244014269	S-formylglutathione hydrolase; Region: PLN02442
1429244014270	Putative esterase; Region: Esterase; pfam00756
1429244014271	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1429244014272	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1429244014273	Predicted membrane protein [Function unknown]; Region: COG2246
1429244014274	GtrA-like protein; Region: GtrA; pfam04138
1429244014275	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1429244014276	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1429244014277	Ligand binding site; other site
1429244014278	Putative Catalytic site; other site
1429244014279	DXD motif; other site
1429244014280	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1429244014281	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1429244014282	CESA_like_2 is a member of the cellulose synthase superfamily; Region: CESA_like_2; cd06427
1429244014283	DXD motif; other site
1429244014284	argininosuccinate lyase; Provisional; Region: PRK00855
1429244014285	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1429244014286	active sites [active]
1429244014287	tetramer interface [polypeptide binding]; other site
1429244014288	argininosuccinate synthase; Provisional; Region: PRK13820
1429244014289	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1429244014290	ANP binding site [chemical binding]; other site
1429244014291	Substrate Binding Site II [chemical binding]; other site
1429244014292	Substrate Binding Site I [chemical binding]; other site
1429244014293	ornithine carbamoyltransferase; Provisional; Region: PRK00779
1429244014294	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1429244014295	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1429244014296	acetylornithine aminotransferase; Provisional; Region: PRK02627
1429244014297	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1429244014298	inhibitor-cofactor binding pocket; inhibition site
1429244014299	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244014300	catalytic residue [active]
1429244014301	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
1429244014302	nucleotide binding site [chemical binding]; other site
1429244014303	N-acetyl-L-glutamate binding site [chemical binding]; other site
1429244014304	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1429244014305	heterotetramer interface [polypeptide binding]; other site
1429244014306	active site pocket [active]
1429244014307	cleavage site
1429244014308	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1429244014309	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1429244014310	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1429244014311	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1429244014312	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244014313	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1429244014314	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1429244014315	peptide chain release factor 2; Provisional; Region: PRK06746
1429244014316	PCRF domain; Region: PCRF; pfam03462
1429244014317	RF-1 domain; Region: RF-1; pfam00472
1429244014318	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1429244014319	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1429244014320	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244014321	nucleotide binding region [chemical binding]; other site
1429244014322	ATP-binding site [chemical binding]; other site
1429244014323	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1429244014324	30S subunit binding site; other site
1429244014325	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014326	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014327	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014328	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014329	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014330	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014331	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014332	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014333	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014334	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014335	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014336	Domain of unknown function DUF11; Region: DUF11; cl17728
1429244014337	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014338	Domain of unknown function DUF11; Region: DUF11; cl17728
1429244014339	Domain of unknown function DUF11; Region: DUF11; cl17728
1429244014340	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014341	Domain of unknown function DUF11; Region: DUF11; cl17728
1429244014342	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1429244014343	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1429244014344	DNA-binding site [nucleotide binding]; DNA binding site
1429244014345	RNA-binding motif; other site
1429244014346	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1429244014347	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
1429244014348	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1429244014349	Sialic acid synthase [Cell envelope biogenesis, outer membrane]; Region: SpsE; COG2089
1429244014350	NeuB family; Region: NeuB; pfam03102
1429244014351	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1429244014352	NeuB binding interface [polypeptide binding]; other site
1429244014353	putative substrate binding site [chemical binding]; other site
1429244014354	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
1429244014355	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244014356	NAD(P) binding site [chemical binding]; other site
1429244014357	active site
1429244014358	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1429244014359	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1429244014360	inhibitor-cofactor binding pocket; inhibition site
1429244014361	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1429244014362	catalytic residue [active]
1429244014363	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1429244014364	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1429244014365	NAD binding site [chemical binding]; other site
1429244014366	homotetramer interface [polypeptide binding]; other site
1429244014367	homodimer interface [polypeptide binding]; other site
1429244014368	substrate binding site [chemical binding]; other site
1429244014369	active site
1429244014370	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1429244014371	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1429244014372	substrate binding site; other site
1429244014373	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1429244014374	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244014375	NAD(P) binding site [chemical binding]; other site
1429244014376	active site
1429244014377	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
1429244014378	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1429244014379	PYR/PP interface [polypeptide binding]; other site
1429244014380	dimer interface [polypeptide binding]; other site
1429244014381	TPP binding site [chemical binding]; other site
1429244014382	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1429244014383	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
1429244014384	TPP-binding site [chemical binding]; other site
1429244014385	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
1429244014386	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1429244014387	NAD(P) binding site [chemical binding]; other site
1429244014388	homodimer interface [polypeptide binding]; other site
1429244014389	substrate binding site [chemical binding]; other site
1429244014390	active site
1429244014391	TPR repeat; Region: TPR_11; pfam13414
1429244014392	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244014393	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244014394	active site
1429244014395	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1429244014396	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1429244014397	active site
1429244014398	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1429244014399	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1429244014400	active site
1429244014401	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244014402	S-adenosylmethionine binding site [chemical binding]; other site
1429244014403	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244014404	TPR repeat; Region: TPR_11; pfam13414
1429244014405	binding surface
1429244014406	TPR motif; other site
1429244014407	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1429244014408	putative metal binding site; other site
1429244014409	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1429244014410	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244014411	binding surface
1429244014412	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1429244014413	TPR motif; other site
1429244014414	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1429244014415	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1429244014416	active site
1429244014417	nucleotide binding site [chemical binding]; other site
1429244014418	HIGH motif; other site
1429244014419	KMSKS motif; other site
1429244014420	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1429244014421	putative metal binding site; other site
1429244014422	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1429244014423	binding surface
1429244014424	TPR motif; other site
1429244014425	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1429244014426	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1429244014427	Flagellar protein FliS; Region: FliS; cl00654
1429244014428	flagellar capping protein; Validated; Region: fliD; PRK07737
1429244014429	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1429244014430	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1429244014431	FlaG protein; Region: FlaG; pfam03646
1429244014432	flagellin; Provisional; Region: PRK12804
1429244014433	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1429244014434	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1429244014435	Global regulator protein family; Region: CsrA; pfam02599
1429244014436	FliW protein; Region: FliW; cl00740
1429244014437	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK07701
1429244014438	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1429244014439	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1429244014440	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
1429244014441	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1429244014442	FlgN protein; Region: FlgN; pfam05130
1429244014443	flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824
1429244014444	flagellar operon protein TIGR03826; Region: YvyF
1429244014445	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244014446	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1429244014447	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244014448	active site
1429244014449	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1429244014450	ATP binding site [chemical binding]; other site
1429244014451	putative Mg++ binding site [ion binding]; other site
1429244014452	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244014453	nucleotide binding region [chemical binding]; other site
1429244014454	ATP-binding site [chemical binding]; other site
1429244014455	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1429244014456	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244014457	active site
1429244014458	phosphorylation site [posttranslational modification]
1429244014459	intermolecular recognition site; other site
1429244014460	dimerization interface [polypeptide binding]; other site
1429244014461	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1429244014462	DNA binding residues [nucleotide binding]
1429244014463	dimerization interface [polypeptide binding]; other site
1429244014464	Sensor protein DegS; Region: DegS; pfam05384
1429244014465	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1429244014466	Histidine kinase; Region: HisKA_3; pfam07730
1429244014467	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244014468	ATP binding site [chemical binding]; other site
1429244014469	Mg2+ binding site [ion binding]; other site
1429244014470	G-X-G motif; other site
1429244014471	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1429244014472	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244014473	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1429244014474	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244014475	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244014476	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1429244014477	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244014478	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244014479	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1429244014480	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1429244014481	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1429244014482	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1429244014483	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1429244014484	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244014485	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1429244014486	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244014487	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1429244014488	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1429244014489	HlyD family secretion protein; Region: HlyD_3; pfam13437
1429244014490	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1429244014491	S-layer homology domain; Region: SLH; pfam00395
1429244014492	S-layer homology domain; Region: SLH; pfam00395
1429244014493	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1429244014494	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1429244014495	Mg++ binding site [ion binding]; other site
1429244014496	putative catalytic motif [active]
1429244014497	substrate binding site [chemical binding]; other site
1429244014498	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1429244014499	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1429244014500	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1429244014501	polysaccharide pyruvyl transferase CsaB; Region: S_layer_CsaB; TIGR03609
1429244014502	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1429244014503	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1429244014504	active site
1429244014505	substrate binding site [chemical binding]; other site
1429244014506	metal binding site [ion binding]; metal-binding site
1429244014507	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1429244014508	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
1429244014509	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1429244014510	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1429244014511	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1429244014512	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1429244014513	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1429244014514	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1429244014515	rod shape-determining protein Mbl; Provisional; Region: PRK13928
1429244014516	MreB and similar proteins; Region: MreB_like; cd10225
1429244014517	nucleotide binding site [chemical binding]; other site
1429244014518	Mg binding site [ion binding]; other site
1429244014519	putative protofilament interaction site [polypeptide binding]; other site
1429244014520	RodZ interaction site [polypeptide binding]; other site
1429244014521	Stage III sporulation protein D; Region: SpoIIID; pfam12116
1429244014522	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1429244014523	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244014524	Stage II sporulation protein; Region: SpoIID; pfam08486
1429244014525	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1429244014526	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1429244014527	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1429244014528	hinge; other site
1429244014529	active site
1429244014530	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
1429244014531	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1429244014532	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1429244014533	gamma subunit interface [polypeptide binding]; other site
1429244014534	epsilon subunit interface [polypeptide binding]; other site
1429244014535	LBP interface [polypeptide binding]; other site
1429244014536	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1429244014537	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1429244014538	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1429244014539	alpha subunit interaction interface [polypeptide binding]; other site
1429244014540	Walker A motif; other site
1429244014541	ATP binding site [chemical binding]; other site
1429244014542	Walker B motif; other site
1429244014543	inhibitor binding site; inhibition site
1429244014544	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1429244014545	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1429244014546	core domain interface [polypeptide binding]; other site
1429244014547	delta subunit interface [polypeptide binding]; other site
1429244014548	epsilon subunit interface [polypeptide binding]; other site
1429244014549	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1429244014550	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1429244014551	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1429244014552	beta subunit interaction interface [polypeptide binding]; other site
1429244014553	Walker A motif; other site
1429244014554	ATP binding site [chemical binding]; other site
1429244014555	Walker B motif; other site
1429244014556	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1429244014557	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1429244014558	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1429244014559	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1429244014560	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1429244014561	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1429244014562	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1429244014563	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1429244014564	ATP synthase I chain; Region: ATP_synt_I; pfam03899
1429244014565	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1429244014566	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1429244014567	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1429244014568	active site
1429244014569	homodimer interface [polypeptide binding]; other site
1429244014570	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244014571	active site
1429244014572	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244014573	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244014574	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244014575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244014576	dimer interface [polypeptide binding]; other site
1429244014577	conserved gate region; other site
1429244014578	putative PBP binding loops; other site
1429244014579	ABC-ATPase subunit interface; other site
1429244014580	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1429244014581	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244014582	dimer interface [polypeptide binding]; other site
1429244014583	conserved gate region; other site
1429244014584	putative PBP binding loops; other site
1429244014585	ABC-ATPase subunit interface; other site
1429244014586	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1429244014587	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1429244014588	dimer interface [polypeptide binding]; other site
1429244014589	active site
1429244014590	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1429244014591	folate binding site [chemical binding]; other site
1429244014592	hypothetical protein; Provisional; Region: PRK13690
1429244014593	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1429244014594	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1429244014595	active site
1429244014596	Predicted membrane protein [Function unknown]; Region: COG1971
1429244014597	Domain of unknown function DUF; Region: DUF204; pfam02659
1429244014598	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1429244014599	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1429244014600	Stage II sporulation protein R (spore_II_R); Region: Spore_II_R; pfam09551
1429244014601	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1429244014602	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244014603	S-adenosylmethionine binding site [chemical binding]; other site
1429244014604	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1429244014605	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1429244014606	RF-1 domain; Region: RF-1; pfam00472
1429244014607	GTP-binding protein YchF; Reviewed; Region: PRK09601
1429244014608	YchF GTPase; Region: YchF; cd01900
1429244014609	G1 box; other site
1429244014610	GTP/Mg2+ binding site [chemical binding]; other site
1429244014611	Switch I region; other site
1429244014612	G2 box; other site
1429244014613	Switch II region; other site
1429244014614	G3 box; other site
1429244014615	G4 box; other site
1429244014616	G5 box; other site
1429244014617	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1429244014618	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1429244014619	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244014620	Coenzyme A binding pocket [chemical binding]; other site
1429244014621	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
1429244014622	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
1429244014623	homotetramer interface [polypeptide binding]; other site
1429244014624	FMN binding site [chemical binding]; other site
1429244014625	homodimer contacts [polypeptide binding]; other site
1429244014626	putative active site [active]
1429244014627	putative substrate binding site [chemical binding]; other site
1429244014628	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1429244014629	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
1429244014630	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1429244014631	ligand binding site [chemical binding]; other site
1429244014632	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1429244014633	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1429244014634	Putative catalytic domain, repeat 1, of uncharacterized phospholipase D-like proteins; Region: PLDc_unchar2_1; cd09129
1429244014635	putative active site [active]
1429244014636	putative catalytic site [active]
1429244014637	Putative catalytic domain, repeat 2, of uncharacterized phospholipase D-like proteins; Region: PLDc_unchar2_2; cd09130
1429244014638	PLD-like domain; Region: PLDc_2; pfam13091
1429244014639	putative active site [active]
1429244014640	putative catalytic site [active]
1429244014641	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1429244014642	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1429244014643	putative active site [active]
1429244014644	catalytic site [active]
1429244014645	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1429244014646	putative active site [active]
1429244014647	catalytic site [active]
1429244014648	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244014649	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244014650	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1429244014651	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1429244014652	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1429244014653	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1429244014654	putative substrate binding site [chemical binding]; other site
1429244014655	putative ATP binding site [chemical binding]; other site
1429244014656	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1429244014657	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244014658	putative DNA binding site [nucleotide binding]; other site
1429244014659	putative Zn2+ binding site [ion binding]; other site
1429244014660	AsnC family; Region: AsnC_trans_reg; pfam01037
1429244014661	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1429244014662	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1429244014663	active site
1429244014664	metal binding site [ion binding]; metal-binding site
1429244014665	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1429244014666	Lysine efflux permease [General function prediction only]; Region: COG1279
1429244014667	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1429244014668	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1429244014669	GTP binding site; other site
1429244014670	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244014671	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1429244014672	putative substrate translocation pore; other site
1429244014673	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1429244014674	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1429244014675	active site
1429244014676	HIGH motif; other site
1429244014677	nucleotide binding site [chemical binding]; other site
1429244014678	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1429244014679	KMSKS motif; other site
1429244014680	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1429244014681	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244014682	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244014683	putative acetyltransferase; Provisional; Region: PRK03624
1429244014684	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244014685	Coenzyme A binding pocket [chemical binding]; other site
1429244014686	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1429244014687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244014688	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1429244014689	putative substrate translocation pore; other site
1429244014690	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1429244014691	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1429244014692	putative [4Fe-4S] binding site [ion binding]; other site
1429244014693	putative molybdopterin cofactor binding site [chemical binding]; other site
1429244014694	The MopB_CT_3 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is of the...; Region: MopB_CT_3; cd02786
1429244014695	putative molybdopterin cofactor binding site; other site
1429244014696	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1429244014697	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1429244014698	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244014699	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1429244014700	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1429244014701	catalytic residues [active]
1429244014702	dimer interface [polypeptide binding]; other site
1429244014703	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1429244014704	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1429244014705	Walker A/P-loop; other site
1429244014706	ATP binding site [chemical binding]; other site
1429244014707	Q-loop/lid; other site
1429244014708	ABC transporter signature motif; other site
1429244014709	Walker B; other site
1429244014710	D-loop; other site
1429244014711	H-loop/switch region; other site
1429244014712	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1429244014713	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1429244014714	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1429244014715	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1429244014716	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1429244014717	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1429244014718	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1429244014719	ATP binding site [chemical binding]; other site
1429244014720	Mg++ binding site [ion binding]; other site
1429244014721	motif III; other site
1429244014722	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244014723	nucleotide binding region [chemical binding]; other site
1429244014724	ATP-binding site [chemical binding]; other site
1429244014725	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1429244014726	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
1429244014727	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1429244014728	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1429244014729	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244014730	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244014731	WHG domain; Region: WHG; pfam13305
1429244014732	Predicted peptidase [General function prediction only]; Region: COG4099
1429244014733	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1429244014734	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1429244014735	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1429244014736	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244014737	substrate binding pocket [chemical binding]; other site
1429244014738	membrane-bound complex binding site; other site
1429244014739	hinge residues; other site
1429244014740	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244014741	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244014742	Walker A/P-loop; other site
1429244014743	ATP binding site [chemical binding]; other site
1429244014744	Q-loop/lid; other site
1429244014745	ABC transporter signature motif; other site
1429244014746	Walker B; other site
1429244014747	D-loop; other site
1429244014748	H-loop/switch region; other site
1429244014749	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244014750	dimer interface [polypeptide binding]; other site
1429244014751	conserved gate region; other site
1429244014752	ABC-ATPase subunit interface; other site
1429244014753	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244014754	dimer interface [polypeptide binding]; other site
1429244014755	conserved gate region; other site
1429244014756	putative PBP binding loops; other site
1429244014757	ABC-ATPase subunit interface; other site
1429244014758	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1429244014759	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1429244014760	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1429244014761	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1429244014762	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1429244014763	oligomeric interface; other site
1429244014764	homodimer interface [polypeptide binding]; other site
1429244014765	putative active site [active]
1429244014766	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
1429244014767	ABC1 family; Region: ABC1; pfam03109
1429244014768	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1429244014769	active site
1429244014770	ATP binding site [chemical binding]; other site
1429244014771	Uncharacterized conserved protein [Function unknown]; Region: COG3937
1429244014772	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1429244014773	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; pfam04014
1429244014774	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1429244014775	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1429244014776	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1429244014777	catalytic triad [active]
1429244014778	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1429244014779	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1429244014780	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1429244014781	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1429244014782	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1429244014783	Diphthamide biosynthesis methyltransferase [Translation, ribosomal structure and biogenesis]; Region: DPH5; COG1798
1429244014784	active site
1429244014785	SAM binding site [chemical binding]; other site
1429244014786	homodimer interface [polypeptide binding]; other site
1429244014787	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1429244014788	active site
1429244014789	SAM binding site [chemical binding]; other site
1429244014790	homodimer interface [polypeptide binding]; other site
1429244014791	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1429244014792	active site
1429244014793	putative homodimer interface [polypeptide binding]; other site
1429244014794	SAM binding site [chemical binding]; other site
1429244014795	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
1429244014796	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244014797	S-adenosylmethionine binding site [chemical binding]; other site
1429244014798	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1429244014799	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1429244014800	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
1429244014801	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1429244014802	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; pfam02571
1429244014803	Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]; Region: COG2138
1429244014804	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
1429244014805	putative active site [active]
1429244014806	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), C-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_C; cd03414
1429244014807	putative active site [active]
1429244014808	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1429244014809	active site
1429244014810	SAM binding site [chemical binding]; other site
1429244014811	homodimer interface [polypeptide binding]; other site
1429244014812	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
1429244014813	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
1429244014814	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1429244014815	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1429244014816	active site
1429244014817	Spore germination protein; Region: Spore_permease; cl17796
1429244014818	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244014819	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244014820	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244014821	Pirin-related protein [General function prediction only]; Region: COG1741
1429244014822	Pirin; Region: Pirin; pfam02678
1429244014823	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1429244014824	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244014825	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244014826	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1429244014827	putative dimerization interface [polypeptide binding]; other site
1429244014828	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1429244014829	EamA-like transporter family; Region: EamA; pfam00892
1429244014830	Cache domain; Region: Cache_1; pfam02743
1429244014831	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244014832	dimerization interface [polypeptide binding]; other site
1429244014833	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1429244014834	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244014835	dimer interface [polypeptide binding]; other site
1429244014836	putative CheW interface [polypeptide binding]; other site
1429244014837	Predicted membrane protein [Function unknown]; Region: COG2259
1429244014838	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1429244014839	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1429244014840	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244014841	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244014842	DNA binding site [nucleotide binding]
1429244014843	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1429244014844	metal binding site 2 [ion binding]; metal-binding site
1429244014845	putative DNA binding helix; other site
1429244014846	metal binding site 1 [ion binding]; metal-binding site
1429244014847	dimer interface [polypeptide binding]; other site
1429244014848	structural Zn2+ binding site [ion binding]; other site
1429244014849	Spore germination protein; Region: Spore_permease; cl17796
1429244014850	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1429244014851	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1429244014852	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1429244014853	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1429244014854	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244014855	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244014856	metal binding site [ion binding]; metal-binding site
1429244014857	active site
1429244014858	I-site; other site
1429244014859	Transcriptional regulator; Region: Rrf2; pfam02082
1429244014860	Rrf2 family protein; Region: rrf2_super; TIGR00738
1429244014861	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1429244014862	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1429244014863	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1429244014864	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
1429244014865	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1429244014866	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK14704
1429244014867	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1429244014868	effector binding site; other site
1429244014869	active site
1429244014870	Zn binding site [ion binding]; other site
1429244014871	glycine loop; other site
1429244014872	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
1429244014873	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1429244014874	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1429244014875	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1429244014876	THF binding site; other site
1429244014877	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1429244014878	substrate binding site [chemical binding]; other site
1429244014879	THF binding site; other site
1429244014880	zinc-binding site [ion binding]; other site
1429244014881	Predicted transcriptional regulators [Transcription]; Region: COG1695
1429244014882	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1429244014883	Protein of unknown function (DUF1700); Region: DUF1700; pfam08006
1429244014884	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
1429244014885	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1429244014886	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1429244014887	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07666
1429244014888	classical (c) SDRs; Region: SDR_c; cd05233
1429244014889	NAD(P) binding site [chemical binding]; other site
1429244014890	active site
1429244014891	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1429244014892	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1429244014893	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1429244014894	Nitric oxide synthase (NOS) produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N(omega)-hydroxy-L-arginine (NHA) as an...; Region: NOS_oxygenase; cd00575
1429244014895	active site
1429244014896	dimer interface [polypeptide binding]; other site
1429244014897	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1429244014898	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1429244014899	dimerization interface [polypeptide binding]; other site
1429244014900	DPS ferroxidase diiron center [ion binding]; other site
1429244014901	ion pore; other site
1429244014902	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1429244014903	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244014904	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1429244014905	active site
1429244014906	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1429244014907	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1429244014908	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244014909	Walker A/P-loop; other site
1429244014910	ATP binding site [chemical binding]; other site
1429244014911	Q-loop/lid; other site
1429244014912	ABC transporter signature motif; other site
1429244014913	Walker B; other site
1429244014914	D-loop; other site
1429244014915	H-loop/switch region; other site
1429244014916	TOBE domain; Region: TOBE_2; pfam08402
1429244014917	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1429244014918	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244014919	dimer interface [polypeptide binding]; other site
1429244014920	conserved gate region; other site
1429244014921	putative PBP binding loops; other site
1429244014922	ABC-ATPase subunit interface; other site
1429244014923	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1429244014924	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244014925	dimer interface [polypeptide binding]; other site
1429244014926	conserved gate region; other site
1429244014927	putative PBP binding loops; other site
1429244014928	ABC-ATPase subunit interface; other site
1429244014929	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1429244014930	active site
1429244014931	tetramer interface [polypeptide binding]; other site
1429244014932	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1429244014933	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1429244014934	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1429244014935	nucleophilic elbow; other site
1429244014936	catalytic triad; other site
1429244014937	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244014938	Protein of unknown function (DUF3380); Region: DUF3380; pfam11860
1429244014939	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1429244014940	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1429244014941	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
1429244014942	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244014943	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244014944	ATP binding site [chemical binding]; other site
1429244014945	Mg2+ binding site [ion binding]; other site
1429244014946	G-X-G motif; other site
1429244014947	nuc_hydro_ TvIAG:  Nucleoside hydrolases similar to the Inosine-adenosine-guanosine-preferring nucleoside hydrolase from Trypanosoma vivax.   Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base; Region: nuc_hydro_TvIAG; cd02647
1429244014948	active site
1429244014949	dimerization interface [polypeptide binding]; other site
1429244014950	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244014951	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1429244014952	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244014953	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1429244014954	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1429244014955	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244014956	putative DNA binding site [nucleotide binding]; other site
1429244014957	putative Zn2+ binding site [ion binding]; other site
1429244014958	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1429244014959	DEAD_2; Region: DEAD_2; pfam06733
1429244014960	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1429244014961	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1429244014962	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1429244014963	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1429244014964	metal binding site [ion binding]; metal-binding site
1429244014965	active site
1429244014966	I-site; other site
1429244014967	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244014968	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244014969	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1429244014970	putative dimerization interface [polypeptide binding]; other site
1429244014971	holin-like protein; Validated; Region: PRK01658
1429244014972	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1429244014973	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1429244014974	glycerol kinase; Provisional; Region: glpK; PRK00047
1429244014975	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1429244014976	N- and C-terminal domain interface [polypeptide binding]; other site
1429244014977	active site
1429244014978	MgATP binding site [chemical binding]; other site
1429244014979	catalytic site [active]
1429244014980	metal binding site [ion binding]; metal-binding site
1429244014981	glycerol binding site [chemical binding]; other site
1429244014982	homotetramer interface [polypeptide binding]; other site
1429244014983	homodimer interface [polypeptide binding]; other site
1429244014984	FBP binding site [chemical binding]; other site
1429244014985	protein IIAGlc interface [polypeptide binding]; other site
1429244014986	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
1429244014987	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1429244014988	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1429244014989	substrate binding pocket [chemical binding]; other site
1429244014990	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244014991	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1429244014992	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1429244014993	NAD binding site [chemical binding]; other site
1429244014994	substrate binding site [chemical binding]; other site
1429244014995	putative active site [active]
1429244014996	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1429244014997	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1429244014998	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1429244014999	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1429244015000	H+ Antiporter protein; Region: 2A0121; TIGR00900
1429244015001	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244015002	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244015003	DNA binding site [nucleotide binding]
1429244015004	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1429244015005	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244015006	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
1429244015007	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1429244015008	NADP binding site [chemical binding]; other site
1429244015009	homodimer interface [polypeptide binding]; other site
1429244015010	active site
1429244015011	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
1429244015012	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1429244015013	active site
1429244015014	intersubunit interface [polypeptide binding]; other site
1429244015015	catalytic residue [active]
1429244015016	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1429244015017	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1429244015018	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1429244015019	substrate binding site [chemical binding]; other site
1429244015020	ATP binding site [chemical binding]; other site
1429244015021	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244015022	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244015023	DNA binding site [nucleotide binding]
1429244015024	domain linker motif; other site
1429244015025	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
1429244015026	putative dimerization interface [polypeptide binding]; other site
1429244015027	putative ligand binding site [chemical binding]; other site
1429244015028	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1429244015029	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1429244015030	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1429244015031	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1429244015032	NAD(P) binding site [chemical binding]; other site
1429244015033	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1429244015034	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244015035	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244015036	DNA binding residues [nucleotide binding]
1429244015037	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1429244015038	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244015039	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015040	putative PBP binding loops; other site
1429244015041	dimer interface [polypeptide binding]; other site
1429244015042	ABC-ATPase subunit interface; other site
1429244015043	sulfate transport protein; Provisional; Region: cysT; CHL00187
1429244015044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015045	dimer interface [polypeptide binding]; other site
1429244015046	conserved gate region; other site
1429244015047	putative PBP binding loops; other site
1429244015048	ABC-ATPase subunit interface; other site
1429244015049	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244015050	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244015051	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1429244015052	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244015053	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1429244015054	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244015055	Walker A/P-loop; other site
1429244015056	ATP binding site [chemical binding]; other site
1429244015057	Q-loop/lid; other site
1429244015058	ABC transporter signature motif; other site
1429244015059	Walker B; other site
1429244015060	D-loop; other site
1429244015061	H-loop/switch region; other site
1429244015062	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1429244015063	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244015064	Walker A/P-loop; other site
1429244015065	ATP binding site [chemical binding]; other site
1429244015066	Q-loop/lid; other site
1429244015067	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244015068	ABC transporter signature motif; other site
1429244015069	Walker B; other site
1429244015070	D-loop; other site
1429244015071	ABC transporter; Region: ABC_tran_2; pfam12848
1429244015072	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1429244015073	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244015074	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244015075	putative substrate translocation pore; other site
1429244015076	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
1429244015077	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1429244015078	Domain of unknown function (DUF377); Region: DUF377; pfam04041
1429244015079	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
1429244015080	active site
1429244015081	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244015082	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015083	dimer interface [polypeptide binding]; other site
1429244015084	conserved gate region; other site
1429244015085	putative PBP binding loops; other site
1429244015086	ABC-ATPase subunit interface; other site
1429244015087	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015088	dimer interface [polypeptide binding]; other site
1429244015089	conserved gate region; other site
1429244015090	putative PBP binding loops; other site
1429244015091	ABC-ATPase subunit interface; other site
1429244015092	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244015093	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244015094	dimerization interface [polypeptide binding]; other site
1429244015095	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
1429244015096	putative active cleft [active]
1429244015097	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
1429244015098	active site
1429244015099	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244015100	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244015101	DNA binding site [nucleotide binding]
1429244015102	domain linker motif; other site
1429244015103	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1429244015104	Cold-inducible protein YdjO; Region: YdjO; pfam14169
1429244015105	hypothetical protein; Provisional; Region: PRK04164
1429244015106	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1429244015107	CsbD-like; Region: CsbD; pfam05532
1429244015108	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244015109	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244015110	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
1429244015111	substrate binding site [chemical binding]; other site
1429244015112	active site
1429244015113	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1429244015114	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1429244015115	Uncharacterized conserved protein [Function unknown]; Region: COG2427
1429244015116	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1429244015117	active site residue [active]
1429244015118	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1429244015119	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1429244015120	active site
1429244015121	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1429244015122	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1429244015123	active site
1429244015124	Na/Ca binding site [ion binding]; other site
1429244015125	catalytic site [active]
1429244015126	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1429244015127	catalytic core [active]
1429244015128	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1429244015129	Bax inhibitor 1 like; Region: BaxI_1; cl17691
1429244015130	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
1429244015131	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1429244015132	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1429244015133	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1429244015134	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
1429244015135	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1429244015136	DNA binding site [nucleotide binding]
1429244015137	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1429244015138	putative dimerization interface [polypeptide binding]; other site
1429244015139	putative ligand binding site [chemical binding]; other site
1429244015140	peptidase T; Region: peptidase-T; TIGR01882
1429244015141	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1429244015142	metal binding site [ion binding]; metal-binding site
1429244015143	dimer interface [polypeptide binding]; other site
1429244015144	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1429244015145	dimer interface [polypeptide binding]; other site
1429244015146	putative CheW interface [polypeptide binding]; other site
1429244015147	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1429244015148	active site
1429244015149	dimer interface [polypeptide binding]; other site
1429244015150	magnesium binding site [ion binding]; other site
1429244015151	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1429244015152	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
1429244015153	tetramer interface [polypeptide binding]; other site
1429244015154	active site
1429244015155	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1429244015156	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1429244015157	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
1429244015158	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244015159	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015160	dimer interface [polypeptide binding]; other site
1429244015161	conserved gate region; other site
1429244015162	ABC-ATPase subunit interface; other site
1429244015163	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1429244015164	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015165	dimer interface [polypeptide binding]; other site
1429244015166	conserved gate region; other site
1429244015167	ABC-ATPase subunit interface; other site
1429244015168	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244015169	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1429244015170	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244015171	HAMP domain; Region: HAMP; pfam00672
1429244015172	Histidine kinase; Region: His_kinase; pfam06580
1429244015173	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244015174	ATP binding site [chemical binding]; other site
1429244015175	Mg2+ binding site [ion binding]; other site
1429244015176	G-X-G motif; other site
1429244015177	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244015178	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
1429244015179	active site
1429244015180	phosphorylation site [posttranslational modification]
1429244015181	intermolecular recognition site; other site
1429244015182	dimerization interface [polypeptide binding]; other site
1429244015183	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015184	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244015185	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244015186	S-adenosylmethionine binding site [chemical binding]; other site
1429244015187	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1429244015188	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1429244015189	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244015190	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1429244015191	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1429244015192	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244015193	Rubredoxin [Energy production and conversion]; Region: COG1773
1429244015194	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1429244015195	iron binding site [ion binding]; other site
1429244015196	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1429244015197	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
1429244015198	ligand binding site [chemical binding]; other site
1429244015199	flexible hinge region; other site
1429244015200	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1429244015201	putative switch regulator; other site
1429244015202	non-specific DNA interactions [nucleotide binding]; other site
1429244015203	DNA binding site [nucleotide binding]
1429244015204	sequence specific DNA binding site [nucleotide binding]; other site
1429244015205	putative cAMP binding site [chemical binding]; other site
1429244015206	Predicted integral membrane protein [Function unknown]; Region: COG5542
1429244015207	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1429244015208	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244015209	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244015210	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244015211	NAD(P) binding site [chemical binding]; other site
1429244015212	active site
1429244015213	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1429244015214	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1429244015215	NAD(P) binding site [chemical binding]; other site
1429244015216	putative active site [active]
1429244015217	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244015218	WHG domain; Region: WHG; pfam13305
1429244015219	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1429244015220	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1429244015221	Walker A/P-loop; other site
1429244015222	ATP binding site [chemical binding]; other site
1429244015223	Q-loop/lid; other site
1429244015224	ABC transporter signature motif; other site
1429244015225	Walker B; other site
1429244015226	D-loop; other site
1429244015227	H-loop/switch region; other site
1429244015228	Uncharacterized protein family (UPF0014); Region: UPF0014; cl00424
1429244015229	General stress protein [General function prediction only]; Region: GsiB; COG3729
1429244015230	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244015231	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015232	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1429244015233	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
1429244015234	Beta-lactamase; Region: Beta-lactamase; pfam00144
1429244015235	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1429244015236	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1429244015237	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244015238	putative DNA binding site [nucleotide binding]; other site
1429244015239	putative Zn2+ binding site [ion binding]; other site
1429244015240	AsnC family; Region: AsnC_trans_reg; pfam01037
1429244015241	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1429244015242	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244015243	putative substrate translocation pore; other site
1429244015244	classical (c) SDRs; Region: SDR_c; cd05233
1429244015245	short chain dehydrogenase; Provisional; Region: PRK07041
1429244015246	NAD(P) binding site [chemical binding]; other site
1429244015247	active site
1429244015248	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244015249	Helix-turn-helix domain; Region: HTH_18; pfam12833
1429244015250	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015251	Glycosyl hydrolase family 52; Region: Glyco_hydro_52; pfam03512
1429244015252	Alpha-glucuronidase [Carbohydrate transport and metabolism]; Region: AguA; COG3661
1429244015253	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
1429244015254	Glycosyl hydrolase family 67 C-terminus; Region: Glyco_hydro_67C; pfam07477
1429244015255	Glycosyl hydrolase family 14; Region: Glyco_hydro_14; pfam01373
1429244015256	Carbohydrate binding domain (family 25); Region: CBM_25; pfam03423
1429244015257	Carbohydrate binding domain (family 25); Region: CBM_25; pfam03423
1429244015258	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_2; cd11339
1429244015259	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1429244015260	active site
1429244015261	catalytic site [active]
1429244015262	Aamy_C domain; Region: Aamy_C; smart00632
1429244015263	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
1429244015264	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244015265	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1429244015266	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1429244015267	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
1429244015268	Walker A/P-loop; other site
1429244015269	ATP binding site [chemical binding]; other site
1429244015270	Q-loop/lid; other site
1429244015271	ABC transporter signature motif; other site
1429244015272	Walker B; other site
1429244015273	D-loop; other site
1429244015274	H-loop/switch region; other site
1429244015275	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1429244015276	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1429244015277	active site
1429244015278	FMN binding site [chemical binding]; other site
1429244015279	substrate binding site [chemical binding]; other site
1429244015280	homotetramer interface [polypeptide binding]; other site
1429244015281	catalytic residue [active]
1429244015282	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1429244015283	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1429244015284	Response regulator receiver domain; Region: Response_reg; pfam00072
1429244015285	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244015286	active site
1429244015287	phosphorylation site [posttranslational modification]
1429244015288	intermolecular recognition site; other site
1429244015289	dimerization interface [polypeptide binding]; other site
1429244015290	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244015291	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015292	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1429244015293	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244015294	dimerization interface [polypeptide binding]; other site
1429244015295	Histidine kinase; Region: His_kinase; pfam06580
1429244015296	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244015297	ATP binding site [chemical binding]; other site
1429244015298	Mg2+ binding site [ion binding]; other site
1429244015299	G-X-G motif; other site
1429244015300	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1429244015301	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015302	dimer interface [polypeptide binding]; other site
1429244015303	conserved gate region; other site
1429244015304	putative PBP binding loops; other site
1429244015305	ABC-ATPase subunit interface; other site
1429244015306	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1429244015307	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015308	dimer interface [polypeptide binding]; other site
1429244015309	conserved gate region; other site
1429244015310	putative PBP binding loops; other site
1429244015311	ABC-ATPase subunit interface; other site
1429244015312	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1429244015313	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1429244015314	Catalytic site [active]
1429244015315	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1429244015316	Right handed beta helix region; Region: Beta_helix; pfam13229
1429244015317	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1429244015318	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1429244015319	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1429244015320	NodB motif; other site
1429244015321	active site
1429244015322	catalytic site [active]
1429244015323	Zn binding site [ion binding]; other site
1429244015324	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1429244015325	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1429244015326	catalytic triad [active]
1429244015327	catalytic triad [active]
1429244015328	oxyanion hole [active]
1429244015329	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1429244015330	putative substrate binding site 1 [chemical binding]; other site
1429244015331	Na binding site 1 [ion binding]; other site
1429244015332	putative substrate binding site 2 [chemical binding]; other site
1429244015333	Na2 binding site [ion binding]; other site
1429244015334	Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]; Region: NtpF; COG2811
1429244015335	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
1429244015336	seryl-tRNA synthetase; Provisional; Region: PRK05431
1429244015337	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1429244015338	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1429244015339	dimer interface [polypeptide binding]; other site
1429244015340	active site
1429244015341	motif 1; other site
1429244015342	motif 2; other site
1429244015343	motif 3; other site
1429244015344	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1429244015345	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1429244015346	heme-binding site [chemical binding]; other site
1429244015347	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1429244015348	FAD binding pocket [chemical binding]; other site
1429244015349	FAD binding motif [chemical binding]; other site
1429244015350	phosphate binding motif [ion binding]; other site
1429244015351	beta-alpha-beta structure motif; other site
1429244015352	NAD binding pocket [chemical binding]; other site
1429244015353	Heme binding  pocket [chemical binding]; other site
1429244015354	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
1429244015355	active site
1429244015356	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1429244015357	sugar binding site [chemical binding]; other site
1429244015358	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
1429244015359	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1429244015360	active site
1429244015361	FMN binding site [chemical binding]; other site
1429244015362	substrate binding site [chemical binding]; other site
1429244015363	putative catalytic residue [active]
1429244015364	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1429244015365	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1429244015366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1429244015367	putative substrate translocation pore; other site
1429244015368	Predicted transcriptional regulators [Transcription]; Region: COG1695
1429244015369	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1429244015370	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1429244015371	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1429244015372	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244015373	DNA-binding site [nucleotide binding]; DNA binding site
1429244015374	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1429244015375	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1429244015376	beta-galactosidase; Region: BGL; TIGR03356
1429244015377	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1429244015378	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
1429244015379	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1429244015380	active site
1429244015381	methionine cluster; other site
1429244015382	phosphorylation site [posttranslational modification]
1429244015383	metal binding site [ion binding]; metal-binding site
1429244015384	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1429244015385	active site
1429244015386	P-loop; other site
1429244015387	phosphorylation site [posttranslational modification]
1429244015388	KWG Leptospira; Region: KWG; pfam07656
1429244015389	Domain of unknown function (DUF4173); Region: DUF4173; pfam13777
1429244015390	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1429244015391	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1429244015392	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1429244015393	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244015394	non-specific DNA binding site [nucleotide binding]; other site
1429244015395	salt bridge; other site
1429244015396	sequence-specific DNA binding site [nucleotide binding]; other site
1429244015397	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244015398	HTH domain; Region: HTH_11; pfam08279
1429244015399	WYL domain; Region: WYL; pfam13280
1429244015400	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1429244015401	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1429244015402	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1429244015403	active site
1429244015404	homodimer interface [polypeptide binding]; other site
1429244015405	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1429244015406	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1429244015407	Walker A/P-loop; other site
1429244015408	ATP binding site [chemical binding]; other site
1429244015409	Q-loop/lid; other site
1429244015410	ABC transporter signature motif; other site
1429244015411	Walker B; other site
1429244015412	D-loop; other site
1429244015413	H-loop/switch region; other site
1429244015414	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015415	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1429244015416	dimer interface [polypeptide binding]; other site
1429244015417	conserved gate region; other site
1429244015418	putative PBP binding loops; other site
1429244015419	ABC-ATPase subunit interface; other site
1429244015420	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1429244015421	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1429244015422	substrate binding pocket [chemical binding]; other site
1429244015423	membrane-bound complex binding site; other site
1429244015424	hinge residues; other site
1429244015425	nickel import ATP-binding protein NikE; Region: nickel_nikE; TIGR02769
1429244015426	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244015427	Walker A/P-loop; other site
1429244015428	ATP binding site [chemical binding]; other site
1429244015429	Q-loop/lid; other site
1429244015430	ABC transporter signature motif; other site
1429244015431	Walker B; other site
1429244015432	D-loop; other site
1429244015433	H-loop/switch region; other site
1429244015434	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244015435	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1429244015436	Walker A/P-loop; other site
1429244015437	ATP binding site [chemical binding]; other site
1429244015438	Q-loop/lid; other site
1429244015439	ABC transporter signature motif; other site
1429244015440	Walker B; other site
1429244015441	D-loop; other site
1429244015442	H-loop/switch region; other site
1429244015443	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244015444	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1429244015445	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015446	dimer interface [polypeptide binding]; other site
1429244015447	conserved gate region; other site
1429244015448	putative PBP binding loops; other site
1429244015449	ABC-ATPase subunit interface; other site
1429244015450	nickel ABC transporter, permease subunit NikB; Region: nickel_nikB; TIGR02789
1429244015451	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015452	dimer interface [polypeptide binding]; other site
1429244015453	conserved gate region; other site
1429244015454	putative PBP binding loops; other site
1429244015455	ABC-ATPase subunit interface; other site
1429244015456	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244015457	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1429244015458	substrate binding site [chemical binding]; other site
1429244015459	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1429244015460	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244015461	Walker A/P-loop; other site
1429244015462	ATP binding site [chemical binding]; other site
1429244015463	Q-loop/lid; other site
1429244015464	ABC transporter signature motif; other site
1429244015465	Walker B; other site
1429244015466	D-loop; other site
1429244015467	H-loop/switch region; other site
1429244015468	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244015469	cell division ATP-binding protein FtsE; Region: FtsE; TIGR02673
1429244015470	Walker A/P-loop; other site
1429244015471	ATP binding site [chemical binding]; other site
1429244015472	Q-loop/lid; other site
1429244015473	ABC transporter signature motif; other site
1429244015474	Walker B; other site
1429244015475	D-loop; other site
1429244015476	H-loop/switch region; other site
1429244015477	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015478	dimer interface [polypeptide binding]; other site
1429244015479	conserved gate region; other site
1429244015480	putative PBP binding loops; other site
1429244015481	ABC-ATPase subunit interface; other site
1429244015482	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244015483	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015484	dimer interface [polypeptide binding]; other site
1429244015485	conserved gate region; other site
1429244015486	putative PBP binding loops; other site
1429244015487	ABC-ATPase subunit interface; other site
1429244015488	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244015489	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_3; cd08490
1429244015490	xanthine permease; Region: pbuX; TIGR03173
1429244015491	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1429244015492	active site
1429244015493	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1429244015494	N- and C-terminal domain interface [polypeptide binding]; other site
1429244015495	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
1429244015496	active site
1429244015497	putative catalytic site [active]
1429244015498	metal binding site [ion binding]; metal-binding site
1429244015499	ATP binding site [chemical binding]; other site
1429244015500	carbohydrate binding site [chemical binding]; other site
1429244015501	L-rhamnose isomerase; Provisional; Region: PRK01076
1429244015502	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1429244015503	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
1429244015504	intersubunit interface [polypeptide binding]; other site
1429244015505	active site
1429244015506	Zn2+ binding site [ion binding]; other site
1429244015507	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1429244015508	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015509	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244015510	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015511	Predicted membrane protein (DUF2157); Region: DUF2157; pfam09925
1429244015512	GDYXXLXY protein; Region: GDYXXLXY; pfam14345
1429244015513	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
1429244015514	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1429244015515	Membrane transport protein; Region: Mem_trans; cl09117
1429244015516	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1429244015517	(R)-2-Hydroxyglutarate Dehydrogenase and related dehydrogenases, NAD-binding and catalytic domains; Region: HGDH_like; cd12184
1429244015518	putative homodimer interface [polypeptide binding]; other site
1429244015519	putative ligand binding site [chemical binding]; other site
1429244015520	putative NAD binding site [chemical binding]; other site
1429244015521	catalytic site [active]
1429244015522	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1429244015523	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244015524	active site
1429244015525	phosphorylation site [posttranslational modification]
1429244015526	intermolecular recognition site; other site
1429244015527	dimerization interface [polypeptide binding]; other site
1429244015528	HTH domain; Region: HTH_11; pfam08279
1429244015529	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1429244015530	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244015531	ATP binding site [chemical binding]; other site
1429244015532	Mg2+ binding site [ion binding]; other site
1429244015533	G-X-G motif; other site
1429244015534	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1429244015535	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1429244015536	heterodimer interface [polypeptide binding]; other site
1429244015537	active site
1429244015538	FMN binding site [chemical binding]; other site
1429244015539	homodimer interface [polypeptide binding]; other site
1429244015540	substrate binding site [chemical binding]; other site
1429244015541	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1429244015542	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1429244015543	FAD binding pocket [chemical binding]; other site
1429244015544	FAD binding motif [chemical binding]; other site
1429244015545	phosphate binding motif [ion binding]; other site
1429244015546	beta-alpha-beta structure motif; other site
1429244015547	NAD binding pocket [chemical binding]; other site
1429244015548	Iron coordination center [ion binding]; other site
1429244015549	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
1429244015550	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244015551	FeS/SAM binding site; other site
1429244015552	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015553	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1429244015554	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015555	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
1429244015556	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244015557	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244015558	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244015559	dimerization interface [polypeptide binding]; other site
1429244015560	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1429244015561	classical (c) SDRs; Region: SDR_c; cd05233
1429244015562	NAD(P) binding site [chemical binding]; other site
1429244015563	active site
1429244015564	Predicted transcriptional regulators [Transcription]; Region: COG1733
1429244015565	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1429244015566	putative DNA binding site [nucleotide binding]; other site
1429244015567	putative Zn2+ binding site [ion binding]; other site
1429244015568	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1429244015569	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1429244015570	short chain dehydrogenase; Provisional; Region: PRK07041
1429244015571	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244015572	NAD(P) binding site [chemical binding]; other site
1429244015573	active site
1429244015574	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244015575	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1429244015576	catalytic residues [active]
1429244015577	dimer interface [polypeptide binding]; other site
1429244015578	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1429244015579	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244015580	DNA-binding interface [nucleotide binding]; DNA binding site
1429244015581	short chain dehydrogenase; Provisional; Region: PRK12939
1429244015582	tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs; Region: THN_reductase-like_SDR_c; cd05362
1429244015583	NADP binding site [chemical binding]; other site
1429244015584	homodimer interface [polypeptide binding]; other site
1429244015585	active site
1429244015586	substrate binding site [chemical binding]; other site
1429244015587	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1429244015588	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1429244015589	ligand binding site [chemical binding]; other site
1429244015590	flexible hinge region; other site
1429244015591	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1429244015592	non-specific DNA interactions [nucleotide binding]; other site
1429244015593	DNA binding site [nucleotide binding]
1429244015594	sequence specific DNA binding site [nucleotide binding]; other site
1429244015595	putative cAMP binding site [chemical binding]; other site
1429244015596	DinB superfamily; Region: DinB_2; pfam12867
1429244015597	Predicted transcriptional regulator [Transcription]; Region: COG2378
1429244015598	HTH domain; Region: HTH_11; pfam08279
1429244015599	WYL domain; Region: WYL; pfam13280
1429244015600	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1429244015601	GIY-YIG motif/motif A; other site
1429244015602	active site
1429244015603	catalytic site [active]
1429244015604	putative DNA binding site [nucleotide binding]; other site
1429244015605	metal binding site [ion binding]; metal-binding site
1429244015606	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244015607	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244015608	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244015609	catalytic residue [active]
1429244015610	phosphonopyruvate decarboxylase; Region: Ppyr-DeCO2ase; TIGR03297
1429244015611	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1429244015612	PYR/PP interface [polypeptide binding]; other site
1429244015613	dimer interface [polypeptide binding]; other site
1429244015614	TPP binding site [chemical binding]; other site
1429244015615	Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as...; Region: TPP_PpyrDC; cd03371
1429244015616	TPP-binding site; other site
1429244015617	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1429244015618	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1429244015619	tetramer interface [polypeptide binding]; other site
1429244015620	active site
1429244015621	Mg2+/Mn2+ binding site [ion binding]; other site
1429244015622	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1429244015623	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1429244015624	Periplasmic copper-binding protein (NosD); Region: NosD; pfam05048
1429244015625	GPR1/FUN34/yaaH family; Region: Grp1_Fun34_YaaH; cl00685
1429244015626	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244015627	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244015628	active site
1429244015629	catalytic tetrad [active]
1429244015630	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1429244015631	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1429244015632	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1429244015633	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1429244015634	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1429244015635	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1429244015636	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1429244015637	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1429244015638	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1429244015639	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1429244015640	Zn2+ binding site [ion binding]; other site
1429244015641	Mg2+ binding site [ion binding]; other site
1429244015642	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244015643	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244015644	active site
1429244015645	phosphorylation site [posttranslational modification]
1429244015646	intermolecular recognition site; other site
1429244015647	dimerization interface [polypeptide binding]; other site
1429244015648	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244015649	DNA binding site [nucleotide binding]
1429244015650	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1429244015651	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244015652	ATP binding site [chemical binding]; other site
1429244015653	Mg2+ binding site [ion binding]; other site
1429244015654	G-X-G motif; other site
1429244015655	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1429244015656	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1429244015657	Walker A/P-loop; other site
1429244015658	ATP binding site [chemical binding]; other site
1429244015659	Q-loop/lid; other site
1429244015660	ABC transporter signature motif; other site
1429244015661	Walker B; other site
1429244015662	D-loop; other site
1429244015663	H-loop/switch region; other site
1429244015664	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1429244015665	FtsX-like permease family; Region: FtsX; pfam02687
1429244015666	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1429244015667	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1429244015668	active site
1429244015669	catalytic tetrad [active]
1429244015670	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
1429244015671	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1429244015672	FeS/SAM binding site; other site
1429244015673	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1429244015674	MarR family; Region: MarR_2; pfam12802
1429244015675	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1429244015676	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244015677	NAD(P) binding site [chemical binding]; other site
1429244015678	active site
1429244015679	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
1429244015680	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1429244015681	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1429244015682	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1429244015683	catalytic residue [active]
1429244015684	Protein of unknown function (DUF1036); Region: DUF1036; cl02296
1429244015685	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1429244015686	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
1429244015687	Uncharacterized conserved protein [Function unknown]; Region: COG2013
1429244015688	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1429244015689	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1429244015690	PhnA protein; Region: PhnA; pfam03831
1429244015691	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1429244015692	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1429244015693	NADP binding site [chemical binding]; other site
1429244015694	putative lipid kinase; Reviewed; Region: PRK13337
1429244015695	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1429244015696	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1429244015697	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
1429244015698	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1429244015699	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1429244015700	active site
1429244015701	P-loop; other site
1429244015702	phosphorylation site [posttranslational modification]
1429244015703	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1429244015704	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1429244015705	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244015706	active site
1429244015707	phosphorylation site [posttranslational modification]
1429244015708	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1429244015709	HTH domain; Region: HTH_11; pfam08279
1429244015710	Mga helix-turn-helix domain; Region: Mga; pfam05043
1429244015711	PRD domain; Region: PRD; pfam00874
1429244015712	PRD domain; Region: PRD; pfam00874
1429244015713	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1429244015714	active site
1429244015715	P-loop; other site
1429244015716	phosphorylation site [posttranslational modification]
1429244015717	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1429244015718	active site
1429244015719	phosphorylation site [posttranslational modification]
1429244015720	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1429244015721	Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs; Region: carb_red_PTCR-like_SDR_c; cd05324
1429244015722	NADP binding site [chemical binding]; other site
1429244015723	substrate binding site [chemical binding]; other site
1429244015724	active site
1429244015725	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1429244015726	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244015727	DNA binding residues [nucleotide binding]
1429244015728	putative dimer interface [polypeptide binding]; other site
1429244015729	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244015730	Coenzyme A binding pocket [chemical binding]; other site
1429244015731	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244015732	Coenzyme A binding pocket [chemical binding]; other site
1429244015733	RDD family; Region: RDD; pfam06271
1429244015734	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1429244015735	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1429244015736	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1429244015737	glycerate kinase; Region: TIGR00045
1429244015738	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1429244015739	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1429244015740	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1429244015741	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244015742	DNA-binding site [nucleotide binding]; DNA binding site
1429244015743	FCD domain; Region: FCD; pfam07729
1429244015744	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
1429244015745	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
1429244015746	N- and C-terminal domain interface [polypeptide binding]; other site
1429244015747	active site
1429244015748	catalytic site [active]
1429244015749	metal binding site [ion binding]; metal-binding site
1429244015750	carbohydrate binding site [chemical binding]; other site
1429244015751	ATP binding site [chemical binding]; other site
1429244015752	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1429244015753	gluconate transporter; Region: gntP; TIGR00791
1429244015754	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1429244015755	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1429244015756	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1429244015757	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244015758	S-adenosylmethionine binding site [chemical binding]; other site
1429244015759	Small Multidrug Resistance protein; Region: Multi_Drug_Res; pfam00893
1429244015760	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244015761	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244015762	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495
1429244015763	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1429244015764	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1429244015765	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1429244015766	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
1429244015767	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244015768	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244015769	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1429244015770	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1429244015771	Coenzyme A binding pocket [chemical binding]; other site
1429244015772	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1429244015773	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1429244015774	ATP binding site [chemical binding]; other site
1429244015775	Mg++ binding site [ion binding]; other site
1429244015776	motif III; other site
1429244015777	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1429244015778	nucleotide binding region [chemical binding]; other site
1429244015779	ATP-binding site [chemical binding]; other site
1429244015780	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
1429244015781	HEAT repeats; Region: HEAT_2; pfam13646
1429244015782	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1429244015783	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1429244015784	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1429244015785	DNA binding residues [nucleotide binding]
1429244015786	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1429244015787	catalytic core [active]
1429244015788	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
1429244015789	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1429244015790	DNA binding residues [nucleotide binding]
1429244015791	dimer interface [polypeptide binding]; other site
1429244015792	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1429244015793	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244015794	S-adenosylmethionine binding site [chemical binding]; other site
1429244015795	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1429244015796	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1429244015797	dimer interface [polypeptide binding]; other site
1429244015798	ADP-ribose binding site [chemical binding]; other site
1429244015799	active site
1429244015800	nudix motif; other site
1429244015801	metal binding site [ion binding]; metal-binding site
1429244015802	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1429244015803	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1429244015804	Helix-turn-helix domain; Region: HTH_18; pfam12833
1429244015805	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1429244015806	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244015807	NAD(P) binding site [chemical binding]; other site
1429244015808	active site
1429244015809	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244015810	malate:quinone oxidoreductase; Validated; Region: PRK05257
1429244015811	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1429244015812	hypothetical protein; Provisional; Region: PRK06761
1429244015813	L-arabinose isomerase; Provisional; Region: PRK02929
1429244015814	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
1429244015815	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1429244015816	trimer interface [polypeptide binding]; other site
1429244015817	substrate binding site [chemical binding]; other site
1429244015818	Mn binding site [ion binding]; other site
1429244015819	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1429244015820	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1429244015821	intersubunit interface [polypeptide binding]; other site
1429244015822	active site
1429244015823	Zn2+ binding site [ion binding]; other site
1429244015824	L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-RBK_like; cd07778
1429244015825	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1429244015826	putative N- and C-terminal domain interface [polypeptide binding]; other site
1429244015827	putative active site [active]
1429244015828	MgATP binding site [chemical binding]; other site
1429244015829	catalytic site [active]
1429244015830	metal binding site [ion binding]; metal-binding site
1429244015831	putative carbohydrate binding site [chemical binding]; other site
1429244015832	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244015833	DNA-binding site [nucleotide binding]; DNA binding site
1429244015834	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1429244015835	Ligand-binding domain of DNA transcription repressor specific for arabinose (AraR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AraR; cd01541
1429244015836	putative dimerization interface [polypeptide binding]; other site
1429244015837	putative ligand binding site [chemical binding]; other site
1429244015838	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1429244015839	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1429244015840	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1429244015841	dimerization interface [polypeptide binding]; other site
1429244015842	NmrA-like family; Region: NmrA; pfam05368
1429244015843	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1429244015844	NAD(P) binding site [chemical binding]; other site
1429244015845	active site
1429244015846	Predicted acyl esterases [General function prediction only]; Region: COG2936
1429244015847	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1429244015848	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1429244015849	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1429244015850	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1429244015851	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1429244015852	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244015853	S-adenosylmethionine binding site [chemical binding]; other site
1429244015854	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1429244015855	Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis]; Region: FusA; COG0480
1429244015856	Tet(M)-like family includes Tet(M), Tet(O), Tet(W), and OtrA, containing tetracycline resistant proteins; Region: TetM_like; cd04168
1429244015857	G1 box; other site
1429244015858	putative GEF interaction site [polypeptide binding]; other site
1429244015859	GTP/Mg2+ binding site [chemical binding]; other site
1429244015860	Switch I region; other site
1429244015861	G2 box; other site
1429244015862	G3 box; other site
1429244015863	Switch II region; other site
1429244015864	G4 box; other site
1429244015865	G5 box; other site
1429244015866	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1429244015867	Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789
1429244015868	Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711
1429244015869	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1429244015870	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1429244015871	cofactor binding site; other site
1429244015872	DNA binding site [nucleotide binding]
1429244015873	substrate interaction site [chemical binding]; other site
1429244015874	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1429244015875	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244015876	non-specific DNA binding site [nucleotide binding]; other site
1429244015877	salt bridge; other site
1429244015878	sequence-specific DNA binding site [nucleotide binding]; other site
1429244015879	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1429244015880	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
1429244015881	polymerase nucleotide-binding site; other site
1429244015882	DNA-binding residues [nucleotide binding]; DNA binding site
1429244015883	nucleotide binding site [chemical binding]; other site
1429244015884	primase nucleotide-binding site [nucleotide binding]; other site
1429244015885	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1429244015886	MPN+ (JAMM) motif; other site
1429244015887	Zinc-binding site [ion binding]; other site
1429244015888	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1429244015889	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1429244015890	catalytic residues [active]
1429244015891	catalytic nucleophile [active]
1429244015892	Recombinase; Region: Recombinase; pfam07508
1429244015893	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1429244015894	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1429244015895	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1429244015896	catalytic residues [active]
1429244015897	catalytic nucleophile [active]
1429244015898	Presynaptic Site I dimer interface [polypeptide binding]; other site
1429244015899	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1429244015900	Synaptic Flat tetramer interface [polypeptide binding]; other site
1429244015901	Synaptic Site I dimer interface [polypeptide binding]; other site
1429244015902	DNA binding site [nucleotide binding]
1429244015903	Recombinase; Region: Recombinase; pfam07508
1429244015904	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1429244015905	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1429244015906	GTP-binding protein YchF; Reviewed; Region: PRK09601
1429244015907	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1429244015908	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244015909	non-specific DNA binding site [nucleotide binding]; other site
1429244015910	salt bridge; other site
1429244015911	sequence-specific DNA binding site [nucleotide binding]; other site
1429244015912	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1429244015913	non-specific DNA binding site [nucleotide binding]; other site
1429244015914	salt bridge; other site
1429244015915	sequence-specific DNA binding site [nucleotide binding]; other site
1429244015916	DinB superfamily; Region: DinB_2; pfam12867
1429244015917	DinB family; Region: DinB; cl17821
1429244015918	Helix-turn-helix domain; Region: HTH_18; pfam12833
1429244015919	YyzF-like protein; Region: YyzF; pfam14116
1429244015920	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244015921	S-adenosylmethionine binding site [chemical binding]; other site
1429244015922	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
1429244015923	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1429244015924	Carbohydrate binding domain X2; Region: CBM_X2; pfam03442
1429244015925	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1429244015926	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1429244015927	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1429244015928	protein binding site [polypeptide binding]; other site
1429244015929	nitrile hydratase, beta subunit; Region: nitrile_beta; TIGR03888
1429244015930	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1429244015931	YycH protein; Region: YycI; cl02015
1429244015932	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
1429244015933	YycH protein; Region: YycH; pfam07435
1429244015934	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1429244015935	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1429244015936	dimerization interface [polypeptide binding]; other site
1429244015937	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1429244015938	putative active site [active]
1429244015939	heme pocket [chemical binding]; other site
1429244015940	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1429244015941	dimer interface [polypeptide binding]; other site
1429244015942	phosphorylation site [posttranslational modification]
1429244015943	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1429244015944	ATP binding site [chemical binding]; other site
1429244015945	Mg2+ binding site [ion binding]; other site
1429244015946	G-X-G motif; other site
1429244015947	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1429244015948	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1429244015949	active site
1429244015950	phosphorylation site [posttranslational modification]
1429244015951	intermolecular recognition site; other site
1429244015952	dimerization interface [polypeptide binding]; other site
1429244015953	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1429244015954	DNA binding site [nucleotide binding]
1429244015955	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1429244015956	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1429244015957	G5 domain; Region: G5; pfam07501
1429244015958	Peptidase family M23; Region: Peptidase_M23; pfam01551
1429244015959	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1429244015960	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1429244015961	DNA-binding site [nucleotide binding]; DNA binding site
1429244015962	UTRA domain; Region: UTRA; pfam07702
1429244015963	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
1429244015964	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1429244015965	active site
1429244015966	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015967	dimer interface [polypeptide binding]; other site
1429244015968	conserved gate region; other site
1429244015969	putative PBP binding loops; other site
1429244015970	ABC-ATPase subunit interface; other site
1429244015971	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1429244015972	hypothetical protein; Provisional; Region: PRK11622
1429244015973	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1429244015974	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1429244015975	Walker A/P-loop; other site
1429244015976	ATP binding site [chemical binding]; other site
1429244015977	Q-loop/lid; other site
1429244015978	ABC transporter signature motif; other site
1429244015979	Walker B; other site
1429244015980	D-loop; other site
1429244015981	H-loop/switch region; other site
1429244015982	TOBE domain; Region: TOBE_2; pfam08402
1429244015983	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1429244015984	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244015985	dimer interface [polypeptide binding]; other site
1429244015986	conserved gate region; other site
1429244015987	putative PBP binding loops; other site
1429244015988	ABC-ATPase subunit interface; other site
1429244015989	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1429244015990	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1429244015991	GDP-binding site [chemical binding]; other site
1429244015992	ACT binding site; other site
1429244015993	IMP binding site; other site
1429244015994	replicative DNA helicase; Provisional; Region: PRK05748
1429244015995	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1429244015996	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1429244015997	Walker A motif; other site
1429244015998	ATP binding site [chemical binding]; other site
1429244015999	Walker B motif; other site
1429244016000	DNA binding loops [nucleotide binding]
1429244016001	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1429244016002	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1429244016003	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1429244016004	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
1429244016005	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1429244016006	DHH family; Region: DHH; pfam01368
1429244016007	Predicted membrane protein (DUF2232); Region: DUF2232; cl01728
1429244016008	MazG-like family; Region: MazG-like; pfam12643
1429244016009	FOG: CBS domain [General function prediction only]; Region: COG0517
1429244016010	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
1429244016011	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1429244016012	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1429244016013	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1429244016014	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1429244016015	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244016016	Walker A/P-loop; other site
1429244016017	ATP binding site [chemical binding]; other site
1429244016018	Q-loop/lid; other site
1429244016019	ABC transporter signature motif; other site
1429244016020	Walker B; other site
1429244016021	D-loop; other site
1429244016022	H-loop/switch region; other site
1429244016023	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244016024	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1429244016025	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1429244016026	Walker A/P-loop; other site
1429244016027	ATP binding site [chemical binding]; other site
1429244016028	Q-loop/lid; other site
1429244016029	ABC transporter signature motif; other site
1429244016030	Walker B; other site
1429244016031	D-loop; other site
1429244016032	H-loop/switch region; other site
1429244016033	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1429244016034	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1429244016035	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1429244016036	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244016037	dimer interface [polypeptide binding]; other site
1429244016038	conserved gate region; other site
1429244016039	putative PBP binding loops; other site
1429244016040	ABC-ATPase subunit interface; other site
1429244016041	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1429244016042	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1429244016043	dimer interface [polypeptide binding]; other site
1429244016044	conserved gate region; other site
1429244016045	putative PBP binding loops; other site
1429244016046	ABC-ATPase subunit interface; other site
1429244016047	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1429244016048	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1429244016049	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1429244016050	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1429244016051	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1429244016052	dimer interface [polypeptide binding]; other site
1429244016053	ssDNA binding site [nucleotide binding]; other site
1429244016054	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1429244016055	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1429244016056	YjzC-like protein; Region: YjzC; pfam14168
1429244016057	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
1429244016058	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1429244016059	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1429244016060	Protein of unknown function (DUF1256); Region: DUF1256; pfam06866
1429244016061	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1429244016062	ParB-like nuclease domain; Region: ParB; smart00470
1429244016063	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1429244016064	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1429244016065	P-loop; other site
1429244016066	Magnesium ion binding site [ion binding]; other site
1429244016067	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1429244016068	Magnesium ion binding site [ion binding]; other site
1429244016069	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1429244016070	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
1429244016071	ParB-like nuclease domain; Region: ParB; smart00470
1429244016072	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1429244016073	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1429244016074	S-adenosylmethionine binding site [chemical binding]; other site
1429244016075	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1429244016076	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
1429244016077	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1429244016078	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1429244016079	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1429244016080	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1429244016081	G1 box; other site
1429244016082	GTP/Mg2+ binding site [chemical binding]; other site
1429244016083	Switch I region; other site
1429244016084	G2 box; other site
1429244016085	Switch II region; other site
1429244016086	G3 box; other site
1429244016087	G4 box; other site
1429244016088	G5 box; other site
1429244016089	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1429244016090	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1429244016091	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
1429244016092	G-X-X-G motif; other site
1429244016093	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
1429244016094	RxxxH motif; other site
1429244016095	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1429244016096	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592